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Sample records for epidemiology directrices para

  1. Subvenciones para instituciones Directrices para gastos de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    División de Administración de Subvenciones ... En la Parte 2 del Acuerdo de Subvención estándar de IDRC se incluyen los límites ... pagar los costos de sustitución (tiempo libre para personal académico) de los investigadores principales.

  2. Directrices para la construcción de un repositorio temático

    Directory of Open Access Journals (Sweden)

    Doria, María Vanesa

    2013-04-01

    Full Text Available La creación de repositorios de información institucionales y/o temáticos, en nuestros días es la clave para el acceso a producción científica de manera libre y abierta. Por lo tanto, el acceso a la información a través de repositorios de información se ve favorecido por las iniciativas que propone el Acceso Abierto (AA. Para la creación de un repositorio de información en el marco de la filosofía de AA es importante contar con directrices, éstas pretenden ser una guía general de aspectos básicos dónde se detallan los pasos necesarios para la creación de un repositorio. El presente trabajo recoge las directrices para la construcción de repositorios temáticos a partir de los siguientes puntos de referencia: finalidad, funciones, políticas y actividades. Aunque existe un consenso sobre que los repositorios temáticos fueron los primeros en aparecer, existe poca información sobre desarrollo y gestión de repositorios temáticos comparado con la amplitud de información alcanzada por repositorios institucionales

  3. Directrices para el diseño curricular en la enseñanza del inglés en el siglo XXI

    OpenAIRE

    Margaret Lee Zoreda; Javier Vivaldo Lima; María Teresa Flores Revilla; Teresita del Rosario Caballero Robles; María Teresa Calderón Rosas

    2006-01-01

    La Universidad Autónoma Metropolitana-Iztapalapa considera fundamental para la enseñanza del inglés como lengua extranjera el crear condiciones para el desarrollo de competencias lingüísticas, comunicativas, interculturales, interdisciplinarias y de pensamiento crítico en dicha lengua extranjera, garantizando así el pleno desarrollo personal, profesional y social de nuestros estudiantes. En este trabajo, se presenta una semblanza de directrices multirregionales que fundamentan el ...

  4. Aplicación de directrices de calidad para la gestión y uso turístico de balnearios y playas

    Directory of Open Access Journals (Sweden)

    Claudia Toselli

    2011-01-01

    Full Text Available La aplicación de estándares de calidad es hoy un tema prioritario en las agendas del turismo internacional. Particularmente, en los últimos años, se ha dedicado mucho esfuerzo al establecimiento de códigos, criterios y sistemas de certificación turística para orientar tanto a los operadores turísticos y los actores locales, como a los propios turistas. En Argentina, ante la necesidad de abocarse a la mejora de la calidad ambiental y turística de la prestación de servicios en playas, los organismos nacionales rectores en materia de turismo, por un lado, y de medio ambiente, por el otro, aunaron esfuerzos para la elaboración de un conjunto de directrices que promovieran la gestión de calidad y el cuidado ambiental en áreas costeras y litorales fluviales, lacustres y marítimas. Estas directrices establecen una serie de lineamientos específicos al respecto, particularmente proveen un marco de referencia para la prestación de servicios en dichas áreas, y actualmente están incluidas en el Sistema Argentino de Calidad Turística. En esta línea, el objetivo de este trabajo ha sido conocer en qué grado estas directrices son aplicadas en balnearios en proceso de consolidación. Para ello se tomaron como estudio de caso dos balnearios de la provincia de Entre Ríos, ubicados en la localidad de Gualeguaychú sobre el margen del río del mismo nombre y bajo concesión por parte del sector privado. A partir de la aplicación de dichas directrices se reconoce que éstas son consideradas de manera parcial en ambos balnearios, lo cual puede encontrar explicación en la falta de obligatoriedad de las mismas. Por lo tanto, en esta directriz se indican algunas recomendaciones sobre las que los balnearios seleccionados tendrían que seguir trabajando y profundizando.

  5. Directrices para la creación de repositorios institucionales en universidades y organizaciones de educación superior

    OpenAIRE

    Bustos González, Atilio; Fernández Porcel, Antonio

    2008-01-01

    El programa ALFA de la Comisión Europea (América Latina Formación Académica) fomenta y apoya las actividades de cooperación entre universidades de ambos continentes1. Las universidades miembros de la Red ALFA Biblioteca de Babel2 asumen como parte de su misión la búsqueda de la excelencia y de la calidad educativa. En la propuesta inicial de trabajo se establecía, como uno de los resultados esperados, la redacción de un documento, a modo de directrices, sobre el desarroll...

  6. Directrices básicas para la auditoría de sistemas de gestión de calidad en instituciones de educación superior

    OpenAIRE

    Vélez C., Manuel; Vélez León, Paulo

    2008-01-01

    International audience; En las páginas siguientes, se presenta un marco de directrices básicas para la auditoría de sistemas de gestión de calidad a las instituciones de educación superior, en especial de sus programas de postgrado. En este trabajo se indaga, básicamente sobre, la conceptualización de la auditoría de sistemas y la particularización de las categorías de auditoría, además se aborda los principios de auditoría, la gestión de un programa de auditoría, las actividades básicas de l...

  7. New guidelines for cardiopulmonary resuscitation Nuevas directrices para la resucitación cardiopulmonar Novas diretrizes da ressuscitação cardiopulmonar

    Directory of Open Access Journals (Sweden)

    Maria Celia Barcellos Dalri

    2008-12-01

    Full Text Available Cardiopulmonary arrest (CPA poses a severe threat to life; cardiopulmonary resuscitation (CPR represents a challenge for research and assessment by nurses and their team. This study presents the most recent international recommendations for care in case of cardiopulmonary heart arrest, based on the 2005 Guidelines by the American Heart Association (AHA. These CPR guidelines are based on a large-scale review process, organized by the International Liaison Committee on Resuscitation (ILCOR. High-quality basic and advanced CPR maneuvers can save lives.La parada cardiorrespiratoria (PCR es una ocurrencia que presenta una grave amenaza a la vida; la resucitación cardiopulmonar (RCP representa un desafío para la investigación y la evaluación por parte del enfermero y su equipo. Este estudio presenta las más recientes recomendaciones internacionales sobre la atención a la parada cardiorrespiratoria, basada en las Directrices de 2005 de la American Heart Asociation (AHA. Esas directrices sobre RCP se fundamentan en un proceso de revisión extenso, organizado por el International Liasion Committee on Resuscitation (ILCOR. Las maniobras básicas y avanzadas de RCP ofrecidas con calidad pueden salvar vidas.A parada cardiorrespiratória (PCR é intercorrência de grave ameaça à vida; a ressuscitação cardiopulmonar (RCP representa desafio para a investigação e a avaliação por parte do enfermeiro e sua equipe. Esse estudo apresenta as mais recentes recomendações internacionais sobre atendimento da parada cardiorrespiratória, baseado nas Diretrizes de 2005 da American Heart Association (AHA. Essas diretrizes sobre RCP fundamentam-se num processo de revisão extenso, organizado pelo International Liasion Committee on Resuscitation (ILCOR. As manobras básicas e avançadas de RCP com qualidade podem salvar vidas.

  8. DIRECTRICES PARA LA CONSTRUCCIÓN DE ARTEFACTOS DE PERSISTENCIA EN EL PROCESO DE DESARROLLO DE SOFTWARE

    Directory of Open Access Journals (Sweden)

    Juan Bernardo Quintero

    2008-07-01

    Full Text Available El almacenamiento de datos es uno de los procesos que se halla en casi la totalidad de los sistemas de información. El tratamiento que se les da a las bases de datos durante el desarrollo de software resulta un factor determinante para el buen desempeño de un sistema. La acelerada evolución tecnológica y el desarrollo de la industria del software han conducido al surgimiento de diversas estrategias de modelado y numerosas técnicas de acceso a datos. En este trabajo se precisan los referentes conceptuales y prácticos para la construcción de los productos relacionados con las bases de datos, el acceso a estas y el tratamiento que se les da en la industria a los llamados artefactos de persistencia.Data storage is a process required in almost every information system nowadays; the treatment given to databases during the software development can be a determining factor in order to achieve good performance of a resulting system. The accelerated technological evolution and the progress of the software enterprises have given rise to diverse modeling strategies and several data access techniques. This work explains the practical and conceptual references for the construction of products related to databases, the access techniques to them and the handling that so-called persistence artifacts have at an industrial level.

  9. Directrices para las transacciones de referencia en la biblioteca del Instituto Nacional de Tecnología Industrial Guidelines for reference transactions in the Library of the Instituto Nacional de Tecnología Industrial

    Directory of Open Access Journals (Sweden)

    Pedro Falcato

    2004-06-01

    Full Text Available El presente artículo expone directrices para las transacciones de referencia en la Biblioteca del INTI. Se describe y justifica su generación a partir de la decisión de integrar esos procedimientos en un sistema de calidad. El objetivo es documentar prácticas consistentes que se desarrollan en el Servicio de Referencia, y establecer recomendaciones acerca de modalidades de trabajo que facilitan la interacción con los usuarios.The present article displays guidelines for reference transactions in the Library of INTI. Its creation is described and justified from the decision to include those procedures in a quality system. The aim is to document sound practices that the Reference Service develops and to set up recommendations on modalities of work that facilitate the interaction with the users.

  10. DIRECTRICES PARA LA ELABORACIÓN DE UN PLAN PARA LA MIGRACIÓN A TELEVISIÓN DIGITAL TERRESTRE (TDT) EN VENEZUELA

    OpenAIRE

    José Rafael Uzcátegui; José Francisco Torres; Nelson Pérez García; Luís Duque; Zeldívar Bruzual

    2010-01-01

    En octubre 2009, la República Bolivariana de Venezuela adoptó el estándar ISDB-Tb (Integrated Services Digital Broadcasting – Terrestrial Built On), de origen japonés, y con las mejoras introducidas por Brasil, como base para el sistema de Televisión Digital Terrestre (TDT) en Venezuela. Con la elección del estándar se inicia el camino hacia la solución de transcendentales aspectos de carácter técnico y legal que permitan la prestación de un servicio de Televisión Digital Terrestre cónsono co...

  11. Las directrices del costo como fuentes de ventajas competitivas.

    Directory of Open Access Journals (Sweden)

    José Reinel Bermeo Muñoz

    2005-01-01

    Full Text Available Este trabajo pretende describir con el mayor detalle y actualización posible el comportamiento de los costos dentro de una actividad de valor con base en los diez factores estructurales que influyen en el costo, denominados por Michael E. Porter (1985, como guías o directrices del costo en su libro La Ventaja Competitiva. Estas directrices actúan como fuentes directas para establecer y sostener el posicionamiento estratégico asumido por la empresa, para determinar la posición relativa de costos y para explicar, en gran parte, la generación temporal de valor en las diversas actividades desarrolladas a lo largo de la cadena de valor. Por esto constituyen uno de los fundamentos para explicar las diferencias de resultados entre empresas pertenecientes al mismo sector de actividad económica y fuentes de ventajas competitivas sostenibles.

  12. Enseñanza de la Guitarra Barroca como instrumento solista: un estudio para el desarrollo de directrices didàcticas.

    OpenAIRE

    Navarro González, Julián

    2008-01-01

    La tesis presenta un estudio detallado del repertorio de la guitarra barroca solista mediante el análisis de 2933 piezas bajo 68 diferentes parámetros. La investigación comienza con la definición del contexto histórico de la guitarra barroca, basado en las publicaciones hechas para el instrumento durante los siglos XVII y XVIII; posteriormente se analiza la situación actual, en donde se mencionan los centros existentes de enseñanzas de Instrumentos de Cuerda Pulsada del Renacimiento y el Barr...

  13. Communications Received from Certain Member States Regarding Guidelines for the Export of Nuclear Material, Equipment and Technology. Nuclear Transfers and Nuclear-Related Dual-Use Transfers; Comunicaciones Recibidas De Diversos Estados Miembros Relativas A Las Directrices Para La Exportacion De Tecnologia, Equipo Y Materiales Nucleares. Transferencias Nucleares Y Transferencias De Equipo, Materiales V Tecnologia Afin Al Doble Uso En Materia Nuclear

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-04-15

    The Director General has received a Note Verbale dated 5 March 1993 from the Ministry of Foreign Affairs of the Slovak Republic. The purpose of the Note Verbale is to provide information on that Governments' guidelines for Nuclear Transfers and for Transfers of of Nuclear-related Dual-use Equipment, Material and Related Technology. In the light of the wish expressed at the end of each Note Verbale, the text of the Note Verbale is annexed hereto [Spanish] El Director General ha recibido una nota verbal de fecha 5 de marzo de 1993 del Ministerio de Relaciones Exteriores de la RepUblica Eslovaca. El objetivo de la nota verbal es proporcionar informaciOn sobre las Directrices para las transferencias nucleares y las Directrices para la transferencia de equipo, materiales y tecnologia afin al doble uso en materia nuclear, de dicho Gobierno. Atendiendo a los deseos expresados al final de la nota verbal, se adjunta al presente documento el texto de la nota verbal.

  14. Novas Diretrizes Curriculares Nacionais para a formação de professores e algumas novas ficções na leitura da escola Nuevas Directrices Curriculares Nacionales para la formación de profesores y algunas nuevas ficciones en la lectura de la escuela New National Curricula Guidelines to Teacher's Training and some new fictions on the reading of the school

    Directory of Open Access Journals (Sweden)

    Rosso Ademir José

    2010-12-01

    Full Text Available Apresenta-se investigação sobre o perfil dos egressos de licenciaturas da Universidade Estadual de Ponta Grossa (UEPG, formados a partir dos novos currículos em consonância com a legislação pós-LDB (BRASIL, 1996. Seus currículos estão adaptados às novas Diretrizes para a formação de professores. O texto usa referências da teoria crítica e freiriana para a perspectiva do letramento entendido como aquisição dos conhecimentos para a docência e da capacidade de recontextualização em situações escolares, no contexto da leitura de mundo. Utiliza procedimentos metodológicos qualitativos e quantitativos em instrumento aplicado aos concluintes de 2008. A análise indica uma tendência adaptativa e não transformadora do contexto escolar. Não se pode afirmar que as alterações promovidas nos cursos tenham logrado, em geral, gerar docentes comprometidos e identificados com a Educação Básica, ou leitores competentes e dialogantes com a realidade escolar.Este texto presenta estudio sobre el perfil de egresados de la licenciatura de la UEPG - Universidad Estadual de Ponta Grossa (ciudad de Paraná, provincia brasileña, graduados a partir de los nuevos currículos según la legislación posterior a la LDB (Ley de Directrices y Bases de la educación nacional brasileña (BRASIL, 1996. Sus currículos están adaptados a las nuevas directrices para la formación de profesores. El texto utiliza referencias de la teoría crítica y también de Paulo Freire para la perspectiva del letramiento entendido como adquisición de los conocimientos para la actividad docente y de la capacidad de recontextualización en situaciones escolares, en el ámbito de la lectura de mundo. Utiliza procedimientos metodológicos cualitativos y cuantitativos en el instrumento aplicado a los concluyentes de 2008. El análisis señala una tendencia adaptativa y no transformadora del contexto escolar. No se puede afirmar que las alteraciones promovidas en los

  15. Therapeutic intervention scoring system-28 (TISS-28: diretrizes para aplicação Therapeutic intervention scoring system-28 (tiss-28: directrices para su aplicación Therapeutic intervention scoring system-28 (tiss-28: directions for application

    Directory of Open Access Journals (Sweden)

    Katia Grillo Padilha

    2005-06-01

    Full Text Available O Therapeutic Intervention Scoring System-28 (TISS-28 é um instrumento que permite dimensionar carga de trabalho de enfermagem em Unidade de Terapia Intensiva e estimar gravidade da doença. Apresenta-se nesta publicação as definições operacionais para sua aplicação, proposta por um grupo de especialistas na área, com vistas a uniformizar o significado de cada um dos itens e evitar vieses de interpretação.El Therapeutic Intervention Scoring System-28 (TISS-28 es un instrumento que permite dimensionar carga de trabajo de enfermería en una Unidad de Terapia Intensiva y estimar la gravedad de la enfermedad. Se presenta en esta publicación las definiciones operacionales para su aplicación, propuesta por un grupo de especialistas en el área, con vistas a uniformizar el significado de cada uno de los items y evitar sesgos de interpretación.Therapeutic Intervention Scoring System-28 (TISS-28 is a tool that enables the measurement of the nursing work load in Intensive Care Units and the estimate of how grave the disease is. In this study are presented the operational definitions for its application, proposed by a group of specialists in the area, with the aim of rendering uniform the meaning of each of the items and preventing interpretation biases.

  16. Lignes directrices canadiennes sur la rhinosinusite chronique

    Science.gov (United States)

    Kaplan, Alan

    2013-01-01

    Résumé Objectif Présenter un résumé clinique des lignes directrices canadiennes sur la rhinosinusite chronique (RSC) qui comporte des recommandations pertinentes aux médecins de famille. Qualité des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique dans la littérature médicale et ont rédigé une ébauche de recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en contenu de l’extérieur, ainsi que l’aval des sociétés médicales (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Canadian Society of Otolaryngology—Head and Neck Surgery, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic d’une RSC se fonde sur le type et la durée des symptômes et une constatation objective d’une inflammation de la muqueuse nasale ou des sinus paranasaux. La rhinosinusite chronique est catégorisée en fonction de la présence ou de l’absence de polypes nasaux et cette distinction entraîne des différences dans le traitement. On traite la rhinosinusite chronique avec polypes nasaux au moyen de corticostéroïdes par voie intranasale. Des antibiotiques sont recommandés quand les symptômes indiquent une infection (douleur ou purulence). Pour une RSC sans polypes nasaux, on recommande des corticostéroïdes par voie intranasale et des antibiotiques de deuxième ligne (par ex. combinaisons amoxicilline–acide clavulanique ou fluoroquinolones à activité accrue contre Gram positif). Une irrigation avec une solution saline, des stéroïdes par voie orale et des tests d’allergies pourraient être appropriées. Si le patient ne répond pas au traitement, il faudrait envisager d

  17. Diretrizes curriculares e estratégias para implantação de uma nova proposta pedagógica Directrices curriculares y estrategias para la implantación de una nueva propuesta pedagógica Curriculum directions and strategies for the implementation of a new pedagogic proposal

    Directory of Open Access Journals (Sweden)

    Josicélia Dumêt Fernandes

    2005-12-01

    Full Text Available O presente estudo busca contribuir com o movimento de transformação a ser desenvolvido nas Escolas/Cursos de Enfermagem. Essa contribuição se refere à formação de enfermeiras(os com autonomia e discernimento, para assegurar a construção do modelo de atenção à saúde, à produção de novos conhecimentos e à prestação de serviços de qualidade voltados para as necessidades de saúde da população, com resolutividade. Traz algumas reflexões conceituais e metodológicas que possam direcionar a mudança no processo de formação de enfermeiras(os, além de apontar estratégias para a implantação da nova proposta pedagógica, baseando-se no desafio da implementação das Diretrizes Curriculares Nacionais do Curso de Graduação em Enfermagem.El presente estudio busca contribuir con el movimiento de transformación a desarrollarse en las Escuelas/Cursos de Enfermería. Esa contribución se refiere a la formación de enfermeras(os con autonomía y discernimiento, para asegurar la construcción del modelo de atención a la salud, la producción de nuevos conocimientos y la prestación de servicios de calidad volcados hacia las necesidades de salud de la población, con resolutividad. Considera algunas reflexiones conceptuales y metodológicas que puedan orientar el cambio en el proceso de formación de enfermeras(os, además de señalar estrategias para la implantación de la nueva propuesta pedagógica, a partir del desafío de la implementación de las Directrices Curriculares Nacionales del Pre Grado en Enfermería.This study is aimed at contributing to the transformation movement to be developed in the Nursing Courses/Schools. The contribution refers to the formation of nurses with autonomy and discernment, to ensure the construction of the model of health attention, to the production of new knowledge and to the delivery of quality services directed to the health needs of the population. This study brings some conceptual and

  18. Directrices para la implementación de un modelo de gestión de la relación con el cliente en el sector industrial: caso DAMERA

    Directory of Open Access Journals (Sweden)

    Jose Luis Wakabayashi

    2015-10-01

    Full Text Available En la presente investigación se aplica el método de caso para analizar la implementación de un modelo de Customer Relationship Management en una empresa industrial. Para este fin se utiliza como base la propuesta de Peppers y Rogers, integrándola en las características y los tipos de demanda propios del sector industrial. A esto se suma el desarrollo de un diagnóstico con miras a evaluar la potencialidad de la empresa para implementar el modelo y la elaboración de una matriz de clasificación del cliente. Finalmente, se aplicó una encuesta a partir de la cual se identificaron las variables para la segmentación de clientes y los puntos de contacto, definiéndose así los grupos de valor para la empresa.

  19. Directrices para la implementación de un modelo de gestión de la relación con el cliente en el sector industrial: caso DAMERA

    Directory of Open Access Journals (Sweden)

    Jose Luis Wakabayashi

    2015-01-01

    Full Text Available En la presente investigación se aplica el método de caso para analizar la implementación de un modelo de Customer Relationship Management en una empresa industrial. Para este fin se utiliza como base la propuesta de Peppers y Rogers, integrándola en las características y los tipos de demanda propios del sector industrial. A esto se suma el desarrollo de un diagnóstico con miras a evaluar la potencialidad de la empresa para implementar el modelo y la elaboración de una matriz de clasificación del cliente. Finalmente, se aplicó una encuesta a partir de la cual se identificaron las variables para la segmentación de clientes y los puntos de contacto, definiéndose así los grupos de valor para la empresa. © 2015 Universidad ICESI. Publicado por Elsevier España, S.L.U. Este es un artículo Open Access bajo la licencia CC BY (http://creativecommons.org/licenses/by/4.0/.

  20. DIRECTRICES METODOLÓGICAS PARA LA OBSERVACIÓN SISTEMÁTICA DEL TIEMPO DE CLASE EN LA INVESTIGACIÓN DE LA EDUCACIÓN FÍSICA

    Directory of Open Access Journals (Sweden)

    J. Viciana

    2010-10-01

    Full Text Available

     

    La gestión del tiempo de clase es una de las competencias docentes que más preocupa a profesores en la enseñanza de la Educación Física (EF, por su importancia en la consecución del aprendizaje (Lozano y Viciana, 2002. El objetivo del presente trabajo es establecer un procedimiento común para el análisis del tiempo de clase que permita la investigación y posible réplica de estudios con el mismo criterio de observación y distinción entre categorías. Para ello, hemos recopilado una serie de consideraciones generales que
    se han de tener presentes en cualquier investigación basada en la observación del tiempo de clase, así como las principales dudas que pueden surgir en su análisis y acuerdos tomados que permitirán sistematizar los registros.
    Palabras clave: Gestión del tiempo de clase, educación física, metodología de análisis observacional.

  1. Communication Received from Certain Member States Regarding Guidelines for Transfers of Nuclear-related Dual-use Equipment, Material, Software and Related Technology; Comunicacion recibida de algunos Estados Miembros relativa a las directrices para las transferencias de equipos, materiales y programas informaticos de doble uso del ambito nuclear y tecnologia afin

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-10-12

    The Agency has received a Note Verbale from the Permanent Mission of Hungary, dated 14 June 2010, in which it requests that the Agency circulate to all Member States a letter of 7 May 2010 from the Chairman of the Nuclear Suppliers Group, Ambassador Ms. Gyorgyi Martin Zanathy, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Iceland, Ireland, Italy, Japan, Kazakhstan, Republic of Korea, Latvia, Lithuania, Luxemburg, Malta, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America,1 providing further information on those Governments' Guidelines for Nuclear Transfers [Spanish] El Organismo ha recibido una nota verbal de la Mision Permanente de Hungria, de fecha 14 de junio de 2010, en la que le solicita que distribuya a todos los Estados Miembros una carta de 7 de mayo de 2010 enviada al Director General por la Presidenta del Grupo de Suministradores Nucleares, la Sra. Embajadora Gyorgyi Martin Zanathy, en nombre de los Gobiernos de Alemania, Argentina, Australia, Austria, Belarus, Belgica, Brasil, Bulgaria, Canada, China, Chipre, Croacia, Dinamarca, Eslovaquia, Eslovenia, Espana, Estados Unidos de America, Estonia, Federacion de Rusia, Finlandia, Francia, Grecia, Hungria, Irlanda, Islandia, Italia, Japon, Kazajstan, Letonia, Lituania, Luxemburgo, Malta, Noruega, Nueva Zelandia, Paises Bajos, Polonia, Portugal, Reino Unido de Gran Bretana e Irlanda del Norte, Republica Checa, Republica de Corea, Rumania, Sudafrica, Suecia, Suiza, Turquia y Ucrania,1 por la que se proporciona mas informacion sobre las Directrices de esos Gobiernos para las transferencias nucleares.

  2. Communication Received from the Permanent Mission of Brazil regarding Certain Member States' Guidelines for the Export of Nuclear Material, Equipment and Technology; Comunicacion recibida de la Mision Permanente del Brasil relativa a las directrices de ciertos Estados Miembros para la exportacion de materiales, equipos y tecnologia nucleares

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-16

    The Agency has received a Note Verbale from the Permanent Mission of Brazil, dated 22 March 2007, in which it requests that the Agency circulate to all Member States a letter of 12 December 2006 from the Chairman of the Nuclear Suppliers Group, Ambassador Jose Artur Denot Medeiros, to the Director General, on behalf of the Governments of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Cyprus, Czech Republic, Denmark, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Kazakhstan, Republic of Korea, Latvia, Lithuania, Luxemburg, Malta, Netherlands, New Zealand, Norway, Poland, Portugal, Romania, Russian Federation, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, providing further information on those Governments' Guidelines for Nuclear Transfers [Spanish] El Organismo ha recibido una nota verbal de la Mision Permanente del Brasil, de fecha 22 de marzo de 2007, en la que le solicita que distribuya a todos los Estados Miembros una carta de 12 de diciembre de 2006 enviada al Director General por el Presidente del Grupo de Suministradores Nucleares, el Embajador Jose Artur Denot Medeiros, en nombre de los Gobiernos de Alemania, Argentina, Australia, Austria, Belarus, Belgica, Brasil, Bulgaria, Canada, Croacia, China, Chipre, Dinamarca, Eslovaquia, Eslovenia, Espana, Estados Unidos de America, Estonia, Federacion de Rusia, Finlandia, Francia, Grecia, Hungria, Irlanda, Italia, Japon, Kazajstan, Letonia, Lituania, Luxemburgo, Malta, Noruega, Nueva Zelandia, Paises Bajos, Polonia, Portugal, Reino Unido de Gran Bretana e Irlanda del Norte, Republica Checa, Republica de Corea, Rumania, Sudafrica, Suecia, Suiza, Turquia y Ucrania, por la que se proporciona mas informacion sobre las Directrices de esos Gobiernos para las transferencias nucleares.

  3. Desafíos a la epidemiología (pasos para una epidemiología "Miltoniana" Challenges to epidemiology (steps to a "Miltonian" epidemiology

    Directory of Open Access Journals (Sweden)

    Juan Samaja

    2003-06-01

    Full Text Available Se sostiene que uno de los grandes desafíos que enfrenta la Epidemiología contemporánea está situado en el campo teórico, y consiste esencialmente en la exigencia de revisar la conceptualización del objeto de la epidemiología dominante que reduce la salud de las poblaciones al comportamiento de los riesgos concebidos con abstracción de los vínculos particulares que los sujetos guardan con sus corporeidades geográficas y medioambientales. El artículo pretende reintroducir la perspectiva dialéctica que deja de lado la visión sustancialista de la realidad de las poblaciones de un lado y del medio ambiente, del otro lado, para proponer una visión estructural, funcional e histórica de ambos conceptos, desarrollando, en este sentido el espíritu de la obra del Gran Geógrafo Brasileiro.This paper argues that one of the major challenges that contemporary Epidemiology has to face is at the level of theory. In essence, it is necessary to revise the abstract conceptualization of the dominant Epidemiology object, which has reduced the health of the population to behavioral risks, without taking into account the link that people have to their geographical and environmental corporities. This article then seeks to reinsert the dialectical perspective that leaves aside the substantialist view of population reality, on one side, and that of the environment, on the other, in order to propose a structural, functional and historical perspective of both concepts, developing, in this way, the spirit of the Great Brazilian Geographer's work.

  4. Multiculturalismo, pesquisa e formação de professores: o caso das Diretrizes Curriculares para a Formação Docente Multiculturalismo, pesquisa y formación de profesores: el caso de las directrices curriculares para la formación docente Multiculturalism, research and teacher training: the case of teacher education

    Directory of Open Access Journals (Sweden)

    Ana Canen

    2005-09-01

    Full Text Available O presente artigo discute possibilidades de articulação de uma perspectiva multicultural ao componente de pesquisa na formação docente, analisando implicações de tal articulação e discutindo a extensão em que está presente no discurso das Diretrizes Curriculares de Formação de Professores (BRASIL, 2000b. Em um primeiro momento, discute o multiculturalismo e a pesquisa, como componentes da formação de professores, levantando tensões e possibilidades em sua articulação; em seguida, relata o contexto em que emergem as recentes políticas educacionais e analisa ênfases e silêncios das diretrizes curriculares nacionais de formação de professores, com relação ao papel da pesquisa e do multiculturalismo em suas formulações. Conclui, indicando a necessidade de se concretizar estratégias multiculturais na formação docente que permitam superar binômios tais como o que separa pesquisa acadêmica de pesquisa prática nessa formação.Este artículo discute las posibilidades de articulación de la perspectiva multicultural al componente de pesquisa en la formación docente, analizando implicaciones de tal articulación y discutiendo la extensión en que está presente en el discurso de las Directrices Curriculares de Formación de Profesores (BRASIL, 2000b. En un primer momento, discute el multiculturalismo y la pesquisa, como componentes de la formación de profesores, levantando tensiones y posibilidades en su articulación; a continuación, relata el contexto en que emergen las recientes políticas educativas y analiza énfasis y silencios de las directrices curriculares nacionales de formación de profesores, con relación al papel de la pesquisa y del multiculturalismo en sus formulaciones. Concluye, señalando la necesidad de concretizar estrategias multiculturales en la formación docente que permitan superar binomios tales como el que separa la pesquisa académica de la pesquisa práctica en esta formación.The present

  5. La epidemiología ocupacional como herramienta básica para la salud de los trabajadores Occupational epidemiology as a basic tool for workers' health

    Directory of Open Access Journals (Sweden)

    Caristina Robaina Aguirre

    2006-06-01

    Full Text Available Se realizó un pequeño bosquejo del desarrollo de la Epidemiología como ciencia y su importancia en salud pública en general. Se transita por las definiciones de vieja y nueva epidemiología, de enfermedades crónicas, transmisibles y no transmisibles, del concepto de epidemiología social, etc. para posteriormente hablar de la importancia de la Epidemiología Ocupacional en la Salud PúblicaA review of the development of Epidemiology as a science, and its significance in public health in general, was made. The old and new definitions of epidemiology, of chronic, transmissible and non-transmissible diseases, of social epidemiology concept, etc., are analysed to further deal with the importance of Occupational Epidemiology in Public Health.

  6. Directrices académico-docentes en el grado de CAV: Un estudio exploratorio multifuente

    Directory of Open Access Journals (Sweden)

    Marina Romeo

    2014-01-01

    Full Text Available En este artículo se presenta una experiencia de investigación en el marco de los estudios de Comunicación Audiovisual de la Universidad de Barcelona. El objetivo ha sido diseñar las directrices académico-docentes de la materia Proyectos del Grado de Comunicación Audiovisual. Durante los meses de octubre y noviembre de 2012, se realizó un estudio cualitativo descriptivo, de carácter exploratorio y con metodología multifuente para identificar aquellos aspectos que permiten el desarrollo de una propuesta didáctica caracterizada por el desarrollo de las competencias del estudiante. Se optó por realizar dos seminarios prospectivos como técnica de recogida de datos. Esta metodología es considerada especialmente útil para estudiar la generación de representaciones sociales, dado que a partir del debate grupal emerge el significado compartido acerca del tema de discusión. Los informantes fueron identificados como clave por el hecho de ser docentes, egresados y/o empleadores de Comunicación Audiovisual. El análisis de contenido muestra un cierto grado de consenso entre profesores, profesionales y egresados con respecto a los conocimientos/habilidades requeridos por los estudiantes y docentes para el desarrollo de un proyecto audiovisual. Se evidencia la conceptualización del proyecto como un proceso y un producto que requiere la puesta en práctica de conocimientos y habilidades, así como el papel relevante que estudiantes y profesores tienen frente a los empleadores. Así mismo se observa el gap existente entre las competencias descritas en la titulación y las expresadas en los seminarios prospectivos. Mientras la titulación apuesta principalmente por el desarrollo de las competencias relativas al “saber hacer”, los empleadores, docentes y egresados focalizan principalmente las relativas al “saber ser”. La principal contribución de esta experiencia es reflexionar sobre los mecanismos que permiten al profesorado diseñar de

  7. Directrices para estructurar un programa de gestión de documentos en las organicaciones

    OpenAIRE

    Zapata, Carlos Alberto

    2005-01-01

    The article treats five great subjects: the symptoms, the problems and the opportunities of the document management in the organizations; the evolution and the consolidation of the document management; the emergent tendencies in the handling of documents; the basic guidelines; the model of documentary management; the structure of a program of documentary management, as well as its implementation and development. It is worth while to emphasize the methodological Model that he proposes for the ...

  8. Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH

    Directory of Open Access Journals (Sweden)

    2001-01-01

    Full Text Available This document presents the most recent update of recommendations from the Department of Health and Human Services of the United States of America concerning the antiretroviral treatment of adolescents and adults who are infected with human immunodeficiency virus (HIV. Among the subjects covered in the document are assessment tests for the viral load, the CD4+ T cell count, and resistance to antiretrovirals; when to begin treatment and with which drugs; when to change treatment and the therapeutic options in that situation; aspects of treating adolescents and pregnant women; treatment adherence; and the drugs' principal side effects. Treatment is indicated for all patients with acute HIV infection, in those who have seroconverted in the preceding 6 months, and in symptomatic patients. With asymptomatic patients, the need for treatment depends on several real or potential risks and benefits. Treatment is usually indicated for asymptomatic individuals with CD4+ T cell counts of 55 000 copies/mL with the reverse transcriptase polymerase chain reaction test. Once treatment has begun, goals should include a maximum and durable suppression of the viral load, restoring or maintaining immune function, improving the quality of life, and reducing HIV-related morbidity and mortality. Treatment results are assessed mainly in terms of the plasma HIV RNA level, which should be undetectable (< 50 copies/mL after 4 to 6 months of treatment. Treatment failure after that period of time can be due to poor treatment adherence, drugs being incompletely suppressive, viral resistance, or other poorly known factors. Treatment should be changed if it fails despite good adherence. This change should be based on a complete analysis of the patient's therapeutic history and on the results of resistance tests.

  9. Directrices para el uso de antirretrovíricos en adolescentes y adultos infectados por VIH

    Directory of Open Access Journals (Sweden)

    2001-09-01

    Full Text Available This document presents the most recent update of recommendations from the Department of Health and Human Services of the United States of America concerning the antiretroviral treatment of adolescents and adults who are infected with human immunodeficiency virus (HIV. Among the subjects covered in the document are assessment tests for the viral load, the CD4+ T cell count, and resistance to antiretrovirals; when to begin treatment and with which drugs; when to change treatment and the therapeutic options in that situation; aspects of treating adolescents and pregnant women; treatment adherence; and the drugs' principal side effects. Treatment is indicated for all patients with acute HIV infection, in those who have seroconverted in the preceding 6 months, and in symptomatic patients. With asymptomatic patients, the need for treatment depends on several real or potential risks and benefits. Treatment is usually indicated for asymptomatic individuals with CD4+ T cell counts of 55 000 copies/mL with the reverse transcriptase polymerase chain reaction test. Once treatment has begun, goals should include a maximum and durable suppression of the viral load, restoring or maintaining immune function, improving the quality of life, and reducing HIV-related morbidity and mortality. Treatment results are assessed mainly in terms of the plasma HIV RNA level, which should be undetectable (< 50 copies/mL after 4 to 6 months of treatment. Treatment failure after that period of time can be due to poor treatment adherence, drugs being incompletely suppressive, viral resistance, or other poorly known factors. Treatment should be changed if it fails despite good adherence. This change should be based on a complete analysis of the patient's therapeutic history and on the results of resistance tests.

  10. Directrices de los Servicios de Salud para Estudiantes Migratorios (Guidelines for Health Services for Migrant Students).

    Science.gov (United States)

    California State Dept. of Education, Sacramento. Bureau of Community Services and Migrant Education.

    To promote uniformity and continuity, standards have been established for planning, implementing, and evaluating student health programs provided by grade K-12 migrant education programs throughout California. In this Spanish language edition, state-mandated health requirements, the rationale for supplemental services, methods of providing…

  11. Lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë

    Science.gov (United States)

    Kaplan, Alan

    2014-01-01

    Résumé Objectif Faire un résumé clinique des lignes directrices canadiennes sur la rhinosinusite bactérienne aiguë (RSBA) qui présente des éléments d’intérêt pour les médecins de famille. Source des données Les auteurs des lignes directrices ont effectué une recherche documentaire systématique et ont rédigé des recommandations. Une cote a été donnée à la fois en fonction de la fiabilité des données probantes et de la solidité des recommandations. On a sollicité les commentaires d’experts en la matière venant de l’extérieur, ainsi que l’aval de sociétés médicales canadiennes (Association pour la microbiologie médicale et l’infectiologie Canada, Société canadienne d’allergie et d’immunologie clinique, Société canadienne d’otorhinolaryngologie et de chirurgie cervicofaciale, Association canadienne des médecins d’urgence et Regroupement canadien des médecins de famille en santé respiratoire). Message principal Le diagnostic de la RSBA repose sur la présence de symptômes particuliers et leur durée; l’imagerie ou une culture n’est pas nécessaire dans les cas peu compliqués. Le traitement dépend de la gravité des symptômes, notamment avec des corticostéroïdes intranasaux (CSIN) recommandés comme monothérapie pour les cas de légers à modérés, quoique leurs bienfaits soient modestes. Le recours à des CSIN accompagnés d’antibiotiques est réservé aux patients qui ne répondent pas aux CSIN après 72 heures et comme traitement initial des patients dont les symptômes sont graves. Le choix de l’antibiotique doit tenir compte du pathogène soupçonné, du risque de résistance, des problèmes concomitants et des tendances locales de la résistance aux antimicrobiens. Des thérapies d’appoint comme l’irrigation nasale avec une solution saline sont recommandées. En présence de cas réfractaires au traitement, d’épisodes récurrents et de signes de complications, on devrait demander une

  12. Avaliação do perfil cinestésico-corporal de crianças com Síndrome de Down: um parâmetro para se atender à proposta das Diretrizes Curriculares Nacionais para a educação especial Evaluación del perfil cinestésico-corporal de niños con Síndrome de Down: un parámetro para atender a la propuesta de las directrices curriculares nacionales para la educación especial The evaluation of the cine-esthetic-corporal profile of children with Down's Syndrome: a parameter to attend the proposal of the national curricular guidelines for special education

    Directory of Open Access Journals (Sweden)

    Ariella Brito

    2009-06-01

    Full Text Available Este artigo teve por objetivo avaliar o perfil cinestésico-corporal de 20 crianças, com Síndrome de Down (SD, de 06 a 12 anos, residentes na Região Sul do Estado do Tocantins - Brasil. Isto com o propósito de estabelecer parâmetros cognitivo-motores que possam fundamentar práticas heterogêneas tanto no projeto político-pedagógico, como no currículo, na metodologia de ensino e na avaliação de tais entes, em conformidade com as Diretrizes Curriculares Nacionais para Educação Especial (BRASIL, 2001 e favorecer, assim, a aprendizagem e a integração social de indivíduos com tais necessidades especiais. Tal objetivo foi alcançado a partir de uma avaliação de contexto na qual foi aplicado o Inventário Portage Operacionalizado (WILLIAMS; AIELLO, 2001 e o protocolo de avaliação de habilidades motoras de Bruininks - Oseretsky (BRUININKS, 1978. Concluiu-se que indivíduos com SD apresentam um deficit de habilidades cognitivo-motoras próprias da coordenação motora fina e um limitado desenvolvimento da linguagem, seja oral ou escrita, resultando em insucesso nas tarefas escolares. Finalmente, chama-se a atenção para um importante aspecto, isto é, que alguns indivíduos portadores da SD, seja em função de um menor nível de deficiência cerebral ou mesmo de vivência motora, podem ter êxito em tarefas diversas, inclusive no ambiente escolar.Este artículo tuvo por objetivo evaluar el perfil cinestésico-corporal de 20 niños, con Síndrome de Down - SD, de 06 a 12 años, residentes en la Región Sur del estado de Tocantins - Brasil. Esto con el propósito de establecer parámetros cognitivo-motores que puedan fundamentar prácticas heterogéneas en el proyecto político-pedagógico, en el currículum, en la metodología de enseñanza y en la evaluación de tales entes, en conformidad con las Directrices Curriculares Nacionales para Educación Especial (MEC/SEESP, 1998, favoreciendo así el aprendizaje y la integración social

  13. Paisajes para un desarrollo sustentable y participativo

    Directory of Open Access Journals (Sweden)

    Rafael Mata Olmo

    2014-11-01

    Para terminar, el texto recoge una experiencia de proyecto territorial de paisaje, la del Plan Insular de Menorca (Islas Baleares, España, aprobado en 2003. Se sintetizan sus determinaciones sobre la protección de determinados terrenos por sus altos valores paisajísticos, sus directrices para que las políticas sectoriales (turismo, agricultura, infraestructuras, etc. incorporen criterios paisajísticos, y sus iniciativas para la gestión y mejora del paisaje y para el fomento del acceso público a su contemplación y disfrute.

  14. La inclusión del sufrimiento psíquico: un desafio para la epidemiologia The inclusion of mental suffering: a challenge for epidemiology

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    Ana Cecília Augsburger

    2004-08-01

    Full Text Available El artículo indaga en qué medida los criterios y las categorías utilizadas para el diagnóstico y la clasificación de los problemas de salud mental, constituyen un obstáculo teórico y metodológico para el desarrollo de la epidemiología en salud mental. Los resultados contemplan dos aspectos. (1Una reflexión teórica destinada a redefinir el objeto de estudio que históricamente la disciplina construyó para sí, analizando de manera crítica las modalidades clasificatorias para los problemas psíquicos. (2Un trabajo de campo en el que se analizan los esquemas teóricos y operativos en los que intervienen los profesionales de la salud mental. Se busca conocer en qué medida tanto las nociones más empíricas, como la formación científica que reciben los psicólogos se adecuan a las categorías propuestas para identificar y diagnosticar las patologías psíquicas (CIE ó DSM. Si el sufrimiento humano no es sólo un problema de orden biológico, sino que es producido en contextos culturales y socio históricos definidos, es necesariamente crítica la mirada sobre sistemas clasificatorios que no contemplan las dimensiones sociales, culturales o institucionales.The article examines in what extend the criteria and the categories used for diagnosis and the classification of mental health problems, are actually theoretical and methodological obstacles for the development of Epidemiology in mental health. The results lead to two main issues: (1 A theoretical consideration pointing to re-define the object of study traditionally built by the discipline itself, analyzing the classificatory schemes for psychics problems. (2 A work in the field analyzing the theoretical and operative schemes in which the professionals in mental health intervene. It tries to clarify in what extend the empirical notions and the scientific skills received by the psychologists, are the correct ones to the categories proposed to identify and diagnose the psychic

  15. Método de captura e recaptura: nova metodologia para pesquisas epidemiológicas Capture-recapture: a new methodology for epidemiological research

    Directory of Open Access Journals (Sweden)

    John Dunn

    1994-12-01

    Full Text Available O método de captura e recaptura, embora não seja novo, tem sido pouco usado em estudos epidemiológicos. Trata-se de método bem adaptável e adequado para estudar populações incomuns ou esquivas, como usuários de drogas endovenosas. Tem sido usado para estudar populações diversas como prostitutas que trabalham na rua ou volume de células vermelhas no homem. Permite ainda estimar a incidência e a prevalência de doenças de forma mais precisa do que os métodos tradicionais e com uma melhor relação custo-benefício. Devido à sua relevância dentro do campo da epidemiologia, decidiu-se realizar uma revisão sobre esse método, enfocando a história, as principais aplicações e apontando as suposições teóricas que o fundamentam. Seu potencial para futuras pesquisas epidemiológicas é promissor.Although capture-recapture method is not new, their use in epidemiological studies has so far been limited. The method was developed by animal ecologists to estimate the size of various species populations, but in recent years it has been used to measure the incidence and prevalence of a variety of non-communicable diseases. Capture-recapture allows more accurate estimates to be made than is the case with traditional methods and is more cost-effective. The method is ideally suited to studying rare or elusive populations, such as intravenous drug misusers; but they are highly adaptable and have been used to study populations as diverse as street working prostitutes and the human red-cell volume. The objectives of this review are to explain the mathematical theory behind capture-recapture, give examples of its use and application in clinical epidemiology and out line some of the modifications that have been made to the theory, which take into account the complex nature of samples used in clinical research. An increasing number of medical epidemoilogists have started to use the method, and its potencial for future epidemiological research is

  16. Hepatitis viral B y Delta en el Perú: epidemiología y bases para su control

    Directory of Open Access Journals (Sweden)

    César Cabezas

    2007-10-01

    Full Text Available El Perú está catalogado como un país de mediana endemicidad para la infección por la hepatitis B (HBV, sin embargo, esta enfermedad se está dispersando en el país por la intensa migración de áreas de alta endemicidad a zonas de baja que endemicidad. Además de los mecanismos clásicos de transmisión de la infección como la vía parenteral y la vía sexual, debe destacarse la transmisión horizontal sobre todo en población infantil de áreas hiperendémicas y la limitada ocurrencia de transmisión vertical a diferencia de Asia. Desde que se cuenta con una vacuna segura y eficaz contra la HBV, se ha desarrollado programas de vacunación piloto en el país, luego de lo cual se ha generalizado la inmunización de la población infantil primero de áreas endémicas y luego a todo el país, según la prioridad y disponibilidad de vacunas. Dada la dispersión de la infección, y para lograr un efectivo control del problema en personas susceptibles, en un menor tiempo, es necesaria la inmunización contra HBV de adolescentes, jóvenes y grupos de riesgo, intervención que es una de las más costo-efectivas en salud pública, mereciendo en el mediano y largo plazo la evaluación de su real impacto. Estos temas son los que se desarrollan en la presente revisión.

  17. Alguns pilares para a apreciação da validade de estudos epidemiológicos Pillars for assessing validity in epidemiological studies

    Directory of Open Access Journals (Sweden)

    Michael E. Reichenheim

    1998-08-01

    Full Text Available Abordagem da questão da validade dos estudos epidemiológicos. Distinguem-se seis tipos de validade. Na validade conceitual enfocam-se os elementos que sustentam a construção de um modelo teórico explicativo do fenômeno de interesse, articulado no plano do discurso e conceitos abstratos. Na validade operacional discutem-se os processos nos quais os conceitos que compõem as diferentes dimensões do modelo teórico são reduzidos a variáveis e indicadores, viabilizando sua instrumentação no nível empírico. À apresentação da validade de domínio, levanta-se a questão da intercambialidade dos indivíduos da população alvo e da população de estudo como sustentação para a generalização dos resultados. A validade de comparação dos grupos de estudo gira em torno da identificação das circunstâncias que rompem a estrutura de comparabilidade, a saber, a situação de confusão e a exclusão seletiva de elementos. À abordagem da validade de informação, aprofundam-se os problemas referentes à aferição/mensuração e os conseqüentes viéses. Visando algumas diretrizes para avaliação da validade de informação, explora-se os fundamentos das relações temporais envolvendo as ocorrências e os processos de coleta. Por fim, apresentam-se algumas importantes questões relacionadas à escolha e validade de especificação do modelo estatístico, bem como comentários sobre as estratégias mais utilizadas na seleção de variáveis e diagnóstico de modelo. Na parte final, sustenta-se que um enfrentamento sistemático das questões de validade pode servir como um dos pilares para a construção do conhecimento em epidemiologia.The article outlines several validity issues in epidemiological studies. Six types of validity are covered. Conceptual validity concerns the elements sustaining a theoretical explanatory model, which, by definition, exists only on an abstract and discursive level. Operational validity concerns the

  18. Epidemiología molecular de la rabia urbana en Colombia, 1994-2004. La rabia en ecosistemas silvestres como amenaza para la población humana

    Directory of Open Access Journals (Sweden)

    Jorge Boshell

    2004-03-01

    Full Text Available

    En Colombia la rabia ocurre en dos ciclos epidemiológicos principales: la rabia urbana con el perro como principal reservorio y transmisor principalmente a humanos, y la rabia silvestre con especies animales de la vida silvestre como los quirópteros y zorros entre otros, como reservorios y transmisores principalmente a especies ganaderas y eventualmente a humanos que se convierten en víctimas accidentales. Durante los últimos años la rabia silvestre en Colombia ha cobrado mayor relevancia como problema de salud pública que la rabia urbana, a juzgar por el número de víctimas humanas. Con el fin de perfeccionar el diagnóstico y la tipificación del virus de la rabia en Colombia, el Laboratorio Nacional de Referencia del Instituto Nacional de Salud estandarizó técnicas para amplificar y secuenciar un fragmento de ADN complementario (cADN a una fracción de 902 nucleótidos seleccionados del ARN del virus, con el fin de adelantar estudios de epidemiología molecular. La fracción mencionada contiene secuencias que codifican para los aminoácidos 447-525 de la glicoproteína y 1-35 de la proteína L. Además contiene la región intergénica no codificante conocida como Pseudogen Psi.

    Las técnicas estandarizadas fueron las siguientes: a extracción de ARN total a partir de cerebro de ratón infectado. b amplificación molecular por transcripción reversa y reacción en cadena de la polimerasa. c secuenciación del fragmento amplificado.

    Mediante estas técnicas de epidemiología molecular viral se determinó que durante 1994-2004, la rabia urbana se concentró en tres regiones geográficas definidas, con epizootias en el antiplano cundiboyacense, departamento de Arauca y la región Caribe. Las dos primeras se controlaron

  19. Profesi Epidemiologi

    Directory of Open Access Journals (Sweden)

    Buchari Lapau

    2011-01-01

    Full Text Available Makalah ini pertama kali menjelaskan perlu adanya profesi kesehatan masyarakat dalam rangka pembangunan kesehatan. Lalu dijelaskan apa profesi itu dan standar keberadaan profesi, atas dasar mana dapat ditetapkan bahwa pelayanan epidemiologi merupakan salah satu profesi. Dalam rangka pembinaan profesi kesehatan masyarakat, IAKMI dan APTKMI telah membentuk Majelis Kolegium Kesehatan Masyarakat Indonesia (MKKMI yang terdiri atas 8 kolegium antara lain Kolegium Epidemiologi, yang telah menyusun Standar Profesi Epidemiologi yang terdiri atas beberapa standar. Masing-masing standar dijelaskan mulai dari kurikulum, standar pelayanan epidmiologi, profil epidemiolog kesehatan, peran epidemiolog kesehatan, fungsi epidemiolog kesehatan, standar kompetensi epidemiologi, dan standar pendidikan profesi epidemiologi.

  20. Lignes directrices sur la prise en charge en soins primaires des céphalées chez l’adulte

    Science.gov (United States)

    Becker, Werner J.; Findlay, Ted; Moga, Carmen; Scott, N. Ann; Harstall, Christa; Taenzer, Paul

    2015-01-01

    Résumé Objectif Accroître l’utilisation d’approches éclairées par des données probantes pour diagnostiquer, investiguer et traiter en soins primaires les céphalées des patients. Qualité des données Une recherche documentaire exhaustive a été effectuée pour trouver des lignes directrices et des révisions systématiques publiées entre janvier 2000 et mai 2011. La grille d’évaluation de la qualité des recommandations pour la pratique clinique AGREE a servi à l’analyse critique des lignes directrices. Les 6 guides de pratique clinique de la plus grande qualité ont servi de base dans le processus d’adaptation. Message principal Un groupe d’élaboration multidisciplinaire de professionnels des soins primaires ont formulé 91 recommandations précises à l’aide d’un processus consensuel. Les recommandations portent sur le diagnostic, l’investigation et la prise en charge de la migraine, de la céphalée de tension, de la céphalée due à une surmédication et de la céphalée vasculaire de Horton. Conclusion Un guide de pratique clinique adapté au contexte des soins de santé au Canada a été produit en suivant un processus d’adaptation de lignes directrices dans le but d’aider les professionnels de toutes les disciplines des soins primaires à dispenser des soins éclairés par des données probantes aux patients souffrant de céphalées.

  1. Limitaciones conceptuales en epidemiología para la clasificación del comportamiento sexual masculino en el contexto de la epidemia de VIH en México

    OpenAIRE

    Uribe Salas, Felipe J.

    2008-01-01

    El papel que la epidemiología ha desempeñado en el estudio de la infección por el virus de inmunodeficiencia humana (VIH), y su diseminación entre la población, ha sido muy relevante. El marco teórico sobre la "etiología multicausal" le ha permitido la identificación de los principales "factores de riesgo" involucrados en la transmisión del VIH, en particular sobre las prácticas sexuales. Sin embargo, ese marco teórico ha tenido limitaciones epistemológicas para estudiar los elementos sociale...

  2. Software development for statistical handling of dosimetric and epidemiological data base; Programacion para la explotacion estadistica de los bancos de datos dosimetrico y epidemiologico

    Energy Technology Data Exchange (ETDEWEB)

    Amaro, M

    1990-07-01

    The dose records from different groups of occupationally exposed workers are available in a computerized data base whose main purpose is the individual dose follow-up. Apart from this objective, such a dosimetric data base can be useful to obtain statistical analysis. The type of statistical n formation that can be extracted from the data base may aim to attain mainly two kinds of objectives: - Individual and collective dose distributions and statistics. -Epidemiological statistics. The report describes the software developed to obtain the statistical reports required by the Regulatory Body, as well as any other type of dose distributions or statistics to be included in epidemiological studies A Users Guide for the operators who handle this software package, and the codes listings, are also included in the report. (Author) 2 refs.

  3. Responsabilidad social de empresas del Distrito Metropolitano de Quito (DMQ) y directrices para mejorar la orientación de sus acciones

    OpenAIRE

    Vela Witt, María Susana

    2014-01-01

    Durante el período 1986 – 2006, el Ecuador experimentó una expansión y presencia de nuevos problemas sociales, a causa del crecimiento de la población, la fuerte migración del campo a la ciudad, el crecimiento de las grandes y medianas ciudades, los bajos presupuestos estatales orientados a atender los problemas sociales, la débil institucionalidad pública, la poca atención dada al tema social por parte de los gobiernos que fueron influenciados por orientaciones político – económicas de corte...

  4. Epidemiology of human papillomavirus infections: new options for cervical cancer prevention Epidemiología de las infecciones por el papilomavirus humano: nuevas opciones para la prevención del cáncer cervical

    Directory of Open Access Journals (Sweden)

    F. Xavier Bosch

    2003-01-01

    Full Text Available In the last two decades, the cervical cancer puzzle has become a coherent description that includes the identification of human papillomavirus (HPV as the sexually transmitted etiologic agent and the characterization of the major determinants of HPV acquisition. Triage studies have consistently shown that HPV testing is more sensitive that repeated cytology in identifying underlying high-grade lesions in women with atypical scamous cells of undetermined significance (ASCUS. Studies that reflect primary screening conditions have shown that the sensitivity of HPV tests is higher than standard cytology in detecting high-grade lesions whereas the specificity is similar only in women aged 30-35 and above. HPV vaccines have an intrinsic attraction as a preventive strategy in populations with limited resources. However, vaccines designed to widespread use are still in development and testing phases. Time is ripe for exploring in depth the clinical implications of current achievements and to devise novel strategies for the prevention of cervical cancer.En las ultimas dos décadas, el enigma del cáncer cervical (CaCu ha comenzado a ser dilucidado y actualmente se ha identificado a la infección por virus de papiloma humano (VPH como su agente etiológico transmitido sexualmente, y se han caracterizado los principales determinantes de infección por VPH. Estudios epidemiológicos han mostrado consistentemente que las pruebas de determinación de ADN de VPH son más sensibles que la citología repetida para la identificación de lesiones de alto grado en mujeres con diagnóstico de células escamosas atípicas de significado indeterminado (ASCUS. Diversos estudios que evalúan el tamizaje primario en CaCu, han mostrado que la sensibilidad de las pruebas de VPH es más alta que la citología estándar para detectar lesiones de alto grado, donde la especificidad es similar sólo en mujeres con edades entre 30 y 35 años o mayores. Las vacunas de VPH tienen

  5. El concepto de materialidad: implicaciones para gerentes e inversionistas

    Directory of Open Access Journals (Sweden)

    Ahmad Hussein Juma’h

    2014-01-01

    Full Text Available Se discuten las implicaciones de la materialidad de la información financiera sobre “manejo de los ingresos”. Implica la descripción y el análisis del contenido de la Codificación de Normas Contables™. Las perspectivas profesionales fueron utilizadas para confirmar la ausencia de directrices de importancia relativa en los Principios de Contabilidad Generalmente Aceptados (en inglés, PCGA de los EE. UU. Los términos “materialidad”, “significancia” e “importancia” fueron usados para determinar la inclusión de materialidad en las codificaciones. Las principales conclusiones indican que, primero, los factores determinantes y las motivaciones internas y externas influyen en las prácticas de “manejos de ganancias” y, segundo, los PCGA de EE. UU. no cuentan con directrices bien definidas para aplicar la materialidad en la toma de decisiones.

  6. Para una epidemiología sociocultural en el estudio del cáncer cervicouterino: experiencias de investigación

    OpenAIRE

    Patricia Aranda G.; Ma. del Carmen Castro V.

    2008-01-01

    El objetivo de este trabajo es contribuir a la discusión en torno a la construcción de una epidemiología sociocultural a partir del análisis de seis investigaciones realizadas en el Programa Salud y Sociedad de El Colegio de Sonora durante los últimos diez años. Todas ellas estudian aspectos relacionados con la prevención y detección oportuna del cáncer cervicouterino desde diferentes ángulos y perspectivas. La revisión de estas experiencias nos invita a distinguir diversos acercamientos entr...

  7. Lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse

    Science.gov (United States)

    Kahan, Meldon; Mailis-Gagnon, Angela; Wilson, Lynn; Srivastava, Anita

    2011-01-01

    Résumé Objectif Présenter aux médecins de famille un résumé clinique pratique des lignes directrices canadiennes sur l’utilisation sécuritaire et efficace des opioïdes pour la douleur chronique non cancéreuse, produites par le National Opioid Use Guideline Group. Qualité des données Pour produire les lignes directrices, les chercheurs ont effectué une synthèse critique de la littérature médicale sur l’efficacité et l’innocuité des opioïdes pour la douleur chronique non cancéreuse et ont rédigé une série de recommandations. Un panel de 49 cliniciens experts de toutes les régions du Canada ont passé en revue l’ébauche et ont atteint un consensus sur 24 recommandations. Message principal Il est recommandé de faire un dépistage du risque de dépendance avant de prescrire des opioïdes. On recommande des opioïdes faibles (codéine et tramadol) pour une douleur de légère à modérée qui n’a pas répondu aux traitements de première intention. On peut essayer l’oxycodone, l’hydromorphone et la morphine chez les patients qui n’ont pas eu de soulagement avec des opioïdes plus faibles. Une faible dose initiale et une lente hausse du titrage sont recommandées, ainsi qu’une étroite surveillance du patient qu’on a d’abord renseigné. Les médecins doivent surveiller l’apparition de complications comme l’apnée du sommeil. La dose optimale est celle qui améliore le fonctionnement ou atténue les cotes d’évaluation de la douleur d’au moins 30 %. Pour la grande majorité des patients, la dose optimale sera bien en deçà de l’équivalent de 200 mg de morphine par jour. On recommande le sevrage progressif pour les patients qui n’ont pas répondu à un essai d’opioïdes adéquat. Conclusion Les opioïdes jouent un rôle important dans la prise en charge de la douleur chronique non cancéreuse, mais il faut en prescrire avec prudence pour limiter les dommages potentiels. Les nouvelles lignes directrices

  8. Raça e epidemiologia: as estratégias para construção de diferenças biológicas Race and epidemiology: strategies to build on biological differences

    Directory of Open Access Journals (Sweden)

    Josué Laguardia

    2007-03-01

    Full Text Available Nas controvérsias atuais sobre raça e diferença racial nos agravos à saúde, a epidemiologia é vista como detentora de autoridade para confirmar ou refutar a verdade científica dessas diferenças. Ao apontar as discussões sobre as limitações da epidemiologia dos fatores de risco, vertente hegemônica nas abordagens epidemiológicas, buscou-se destacar nesse artigo o caráter ideológico dos pressupostos causais e as estratégias epistemológicas que reiteram e reificam as diferenças raciais na saúde com base no determinismo biológico e no reducionismo estatístico. O objetivo deste trabalho é destacar as possibilidades de contestação de algumas interpretações dos achados epidemiológicos sobre diferenças raciais na saúde, enfatizando os aspectos políticos e ideológicos da ciência e provendo os investigadores de argumentos que ajudem a superar o racialismo que permeia algumas hipóteses causais acerca da diversidade humana e doença.In the current controversies about race and racial differences in health, epidemiology is seen as the authority that confirms or refutes the scientific truth of these differences. Pointing out the current discussions about the limitations of risk factor epidemiology, hegemonic branch of the epidemiological approaches, it is the aim of this article to highlight the ideological character of the causal assumptions and epistemological strategies that restate and reify the racial differences in health based on biological determinism and statistical reductionism. The objective of this work is to highlight the possibilities of contestation of some interpretations about epidemiological findings on racial differences in health, emphasizing the political and ideological aspects of science and providing the investigators with arguments that can help to overcome the racialism that permeates certain causal hypothesis about human diversity and disease.

  9. Epidemiology of gastric cancer and perspectives for prevention Epidemiología del cáncer gástrico y perspectivas para su prevención

    Directory of Open Access Journals (Sweden)

    NUBIA MUÑOZ

    1997-07-01

    Full Text Available The most recent estimates of the world-wide incidence of cancer indicate that gastric cancer was in 1990 the second most frequent cancer in the world (after lung cancer, with about 900 000 new cases diagnosed every year. Steady declines in the rates have been observed everywhere in the last few decades, but the absolute number of new cases per year is increasing mainly because of ageing of the population. The exact causes of the decline of gastric cancer are not well understood, but must include improvements in diet, food storage (e.g., refrigeration and, possibly, the decline of Helicobacter pylori infection. Dietary modifications and, possibly, vitamin supplements remain one of the most important tool for the prevention of gastric cancer. Control of H. pylori infection, by means of eradication or immunization, is also likely to offer great potential for the prevention of this important malignancy.Las estimaciones más recientes sobre la incidencia de cáncer a nivel mundial indican que, en 1990, el gástrico fue el segundo más frecuente (después del pulmonar, con aproximadamente 900 000 casos nuevos diagnosticados cada año. Durante las últimas décadas, las tasas de incidencia de esta enfermedad han disminuido en forma constante en casi todo el mundo; sin embargo, el número absoluto de casos nuevos por año continúa en aumento debido, primordialmente, a que la población cuenta con un mayor número de personas de edad avanzada. No se sabe con exactitud a qué se debe esta disminución de casos de cáncer gástrico, pero entre las causas se mencionan: mejoras tanto en la dieta como en la conservación de los alimentos (p.e., por medio de la refrigeración y una disminución de las infecciones por Helicobacter pylori. Las modificaciones a la dieta y, posiblemente, el consumo de complementos vitamínicos continúan siendo las alternativas más importantes para prevenir el cáncer gástrico. Asimismo, es probable que el control de la infecci

  10. Fundamentos para la creación de actividades con material real

    Directory of Open Access Journals (Sweden)

    Román Navarro Giner

    2008-01-01

    Full Text Available En esta experiencia práctica pretendemos mostrar algunas pautas para transformar cualquier material real atractivo para el profesor en actividades aplicables a la clase de español, basándonos en las directrices propuestas por el Marco común europeo de referencia para las lenguas (MCER y teniendo en cuenta los contenidos que marcan los Niveles de Referencia (en adelante, NR del Instituto Cervantes. Para ello se comentarán en primer lugar las particularidades teóricas que la actividad requiere, para ver a continuación un ejemplo de diseño de actividad en el que combinaremos un microcuento, un artículo periodístico, el concurso de un periódico en internet y el uso de la mensajería móvil.

  11. Fundamentos para la creación de actividades con material real

    Directory of Open Access Journals (Sweden)

    Román Navarro Giner

    2012-08-01

    Full Text Available En esta experiencia práctica pretendemos mostrar algunas pautas para transformar cualquier material real atractivo para el profesor en actividades aplicables a la clase de español, basándonos en las directrices propuestas por el Marco común europeo de referencia para las lenguas (MCER y teniendo en cuenta los contenidos que marcan los Niveles de Referencia (en adelante, NR del Instituto Cervantes. Para ello se comentarán en primer lugar las particularidades teóricas que la actividad requiere, para ver a continuación un ejemplo de diseño de actividad en el que combinaremos un microcuento, un artículo periodístico, el concurso de un periódico en internet y el uso de la mensajería móvil.

  12. Epidemiological causality.

    Science.gov (United States)

    Morabia, Alfredo

    2005-01-01

    Epidemiological methods, which combine population thinking and group comparisons, can primarily identify causes of disease in populations. There is therefore a tension between our intuitive notion of a cause, which we want to be deterministic and invariant at the individual level, and the epidemiological notion of causes, which are invariant only at the population level. Epidemiologists have given heretofore a pragmatic solution to this tension. Causal inference in epidemiology consists in checking the logical coherence of a causality statement and determining whether what has been found grossly contradicts what we think we already know: how strong is the association? Is there a dose-response relationship? Does the cause precede the effect? Is the effect biologically plausible? Etc. This approach to causal inference can be traced back to the English philosophers David Hume and John Stuart Mill. On the other hand, the mode of establishing causality, devised by Jakob Henle and Robert Koch, which has been fruitful in bacteriology, requires that in every instance the effect invariably follows the cause (e.g., inoculation of Koch bacillus and tuberculosis). This is incompatible with epidemiological causality which has to deal with probabilistic effects (e.g., smoking and lung cancer), and is therefore invariant only for the population.

  13. Epidemiology of snakebite accidents in the municipalities of the state of Paraíba, Brazil Epidemiologia dos acidentes ofídicos ocorridos nos municípios do Estado da Paraíba, Brasil

    Directory of Open Access Journals (Sweden)

    Rafaella Moreno Barros

    2013-05-01

    Full Text Available Accidents involving venomous animals represent an important, albeit neglected, public health issue worldwide. A descriptive study was made of snakebite cases attended and recorded between 2007 and 2010 in the health units of the municipalities of Cariri, State of Paraíba, northeastern Brazil. Data was collected from the Injury Notification Information System data banks of the Health Ministry and a total of 351 records of snakebite victims were reviewed. Victims were predominantly male farm workers over 50. The highest incidence of snakebites occurred in rural areas, between April and June of 2007 and 2010. Snakes of the genus Bothrops were responsible for most cases, and victims were mostly bitten on the feet. The majority of the victims received medical assistance within 1 to 3 hours after being bitten. The most common clinical manifestations were pain, edema and ecchymosis, which were mainly classified as mild or moderate. Two deaths were reported. It was concluded that there is a significant impact of seasonality in snakebites, the prevalence of attacks caused by Bothrops, affecting the lower limbs of adult male farmers in rural areas. The findings of this study may contribute to identify the conditions that increase the risk of snake attacks in the northeastern region.Acidentes por animais peçonhentos representam um importante, embora negligenciado, problema de saúde pública mundial. Neste sentido, foi realizado um estudo descritivo dos acidentes ofídicos atendidos e registrados, entre 2007 e 2010, nas unidades de saúde dos municípios do Cariri, Estado da Paraíba, Nordeste do Brasil. As informações foram coletadas do banco de dados do Sistema de Informação de Agravos de Notificação do Ministério da Saúde. Um total de 351 registros de vítimas de ataques por serpentes peçonhentas foram analisados. As vítimas foram predominantemente trabalhadores rurais do sexo masculino com mais de 50 anos. As maiores incidências de

  14. Aspectos de importância para a vigilância epidemiológica da poliomielite na cidade de São Paulo, Brasil Important epidemiological aspects of poliomyelitis in the city of S. Paulo, Brazil

    Directory of Open Access Journals (Sweden)

    Victório Barbosa

    1980-12-01

    Full Text Available São apresentados diversos aspectos epidemiológicos da poliomielite na Capital de São Paulo (Brasil. De sua análise resultaram algumas conclusões de importância para a manutenção do controle dessa doença em nosso meio. Verificou-se a absoluta necessidade de se manter continuamente a cobertura vacinal da população infantil, pois a diminuição de intensidade na aplicação da vacina Sabin poderá trazer o imediato recrudescimento da doença entre nós. Após um período de 4 anos de controle efetivo sobre a poliomielite, no qual ocorreram, em média, 58 casos de doença paralítica por ano, foram registrados no ano de 1971 195 casos. A situação somente voltou a ser efetivamente controlada no segundo semestre de 1975, quando os programas de imunização foram novamente incrementados. O estudo mostrou que a poliomielite continua apresentando entre nós as clássicas feições da paralisia infantil, ocorrendo cerca de 75% dos casos nos dois primeiros anos de vida das crianças. Este fato, juntamente com a evidência de que o poliovírus do tipo 1 continua prevalecendo em nosso meio, tendo causado a grande maioria dos casos de doença paralitica nos últimos anos, indica que a epidemiologia da virose ainda não foi essencialmente alterada pelos programas de vacinação. Verificou-se, que a vacinação Sabin tem sido menos eficiente em nosso meio do que nos países altamente desenvolvidos e de clima temperado, devido à interferência de uma série de fatores epidemiológicos e operacionais. No período de 1970 a 1977 8,9% dos pacientes investigados tinha recebido, no passado, 3 e 4 e mais doses de vacina oral trivalente e 43,3% tinha tomado pelo menos uma dose de vacina oral. Recomenda-se às autoridades sanitárias que o número de doses de vacina da série básica de imunização contra a poliomielite seja aumentado de três para cinco, com a finalidade de se compensar as falhas que ocorrem na prática da vacinação oral e de se poder

  15. Mathematical epidemiology

    CERN Document Server

    Driessche, Pauline; Wu, Jianhong

    2008-01-01

    Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downlo...

  16. EPRI epidemiology

    International Nuclear Information System (INIS)

    Anon.

    1991-01-01

    A fight is brewing within the electric power community over the fate of a proposed $5 to $8 million epidemiological study of the effects of radiation on US nuclear plant workers. Several industry experts, claiming the project would merely lead to confusion by producing no clear results, are trying to prevent the Electric Power Research Institute (EPRI) from funding what would be the largest ever occupational study of this kind, covering perhaps as many as 500,000 workers. Ralph Lapp, a well-known radiation physicist, says that EPRI is facing unprecedented technical dissent from within. He claims there is already plenty of evidence that nuclear utilities are among the safest places to work, at least in terms of cancer risk, and that the proposed EPRI study would raise new concerns without yielding any answers

  17. Epidemiología de campo y epidemiología social Field epidemiology and social epidemiology

    Directory of Open Access Journals (Sweden)

    Javier Segura del Pozo

    2006-03-01

    Full Text Available Mediante la comparación de la epidemiología de campo y la epidemiología social, se pretende reflexionar sobre los imaginarios no explícitos que operan en ambos ámbitos, necesariamente convergentes, sobre los obstáculos de la práctica epidemiológica actual para alcanzar su función social y sobre la necesidad de cambiar las bases epistemológicas, metodológicas y prácticas que operan en la epidemiología, empezando por la formación del epidemiólogo de campo. La epidemiología de campo tiende a la acción sin marco teórico. La epidemiología social, por el contrario, tiende a los desarrollos teóricos (reflexión e investigación sobre los determinantes sociales alejados de la acción, debido a los limitantes para cambiar las políticas públicas. Otras diferencias se sitúan en el nivel de intervención (micro/macroespacios, el objeto de intervención (control del brote frente a control de las desigualdades y en la forma de articular la comunicación con la sociedad. Se asemejan en la preocupación por el método, la predominancia de una orientación positivista y condicionada por la estadística, aunque en proceso de cierta apertura epistemológica, la tensión experimentada entre relacionarse con un mundo virtual de bases de datos o con la sociedad real, su situación en la periferia del sistema político-social-institucional-profesional y por estar abocadas a la frustración profesional. Finalmente, se formulan 10 interrogantes a los epidemiólogos de campo sobre su práctica actual, a través de los cuales se podría evaluar si están realizando una epidemiología social, y se sugieren cambios para introducir en la formación y práctica del epidemiólogo.Comparing field epidemiology and social epidemiology, we pretend to think about the no explicit images and meanings operating in both necessary convergent fields, about the obstacles present in epidemiological practice to fulfil its social function and about the necessity of

  18. Gestion del mecanismo de traspaso para trafico IP en los sistemas móviles celulares de tercera generacion

    OpenAIRE

    Ferrús Ferré, Ramón Antonio; Díaz Romero, M. del Pilar

    1999-01-01

    Entre las principales directrices que actualmente determinan la evolución de las redes de telecomunicación se encuentra la adopción progresiva de tecnologías de transmisión en modo paquete. Bajo esta perspectiva, el presente trabajo describe una posible arquitectura para la integración de diferentes redes de acceso a una plataforma troncal IP y plantea el análisis de las prestaciones de los algoritmos de traspaso en función de las entidades funcionales del plano de transmisión involucradas. ...

  19. Epidemiological changes and financial consequences of hypertension in Latin America: implications for the health system and patients in Mexico Cambios epidemiológicos y consecuencias financieras de la hipertensión en América Latina: implicaciones para el sistema de salud y los pacientes en México

    Directory of Open Access Journals (Sweden)

    Armando Arredondo

    2012-03-01

    Full Text Available The aim of this study was to assess the costs and financial consequences of epidemiological changes in hypertension in México. The cost evaluation method to estimate costs was based on instrumentation techniques. To estimate the epidemiological changes and expected cases of hypertension in 2010-2012, three probabilistic models were constructed according to the Box-Jenkins technique. Comparing the economic impact, from 2010 to 2012 there will be a 24% increase in financial requirements (p El objetivo fue identificar los costos y las consecuencias financieras de cambios epidemiológicos referentes a la hipertensión en México. El método de evaluación de los costos, para estimar los costos directos e indirectos, se basó en técnicas de instrumentación y de consenso. Para estimar los cambios epidemiológicos y de casos esperados para el período 2010-2012, tres modelos probabilísticos se construyeron de acuerdo a la técnica de Box-Jenkins. Al comparar el impacto económico en el 2010 frente a 2012 (p < 0.05, hay un incremento del 24% de las necesidades financieras. El importe total para la hipertensión en 2011 será de US$ 5.733.350.291. Se incluyen US$ 2.718.280.941 en costos directos y US$ 3.015.069.350 en costos indirectos. Si los factores de riesgo y los modelos de atención a la salud permanecen sin cambios, las consecuencias financieras serían de mayor impacto para los bolsillos de los usuarios, siguiendo en orden de importancia, los proveedores de seguridad social y los proveedores de asistencia pública.

  20. Coccidioidomycosis: epidemiology

    Directory of Open Access Journals (Sweden)

    Brown J

    2013-06-01

    Full Text Available Jennifer Brown,1 Kaitlin Benedict,2 Benjamin J Park,2 George R Thompson III1,31Department of Internal Medicine, Division of Infectious Diseases, University of California, Davis Medical Center, Sacramento, CA, USA; 2Mycotic Diseases Branch, Division of Foodborne, Waterborne, and Environmental Diseases, US Centers for Disease Control and Prevention, Atlanta, GA, USA; 3Department of Medical Microbiology and Immunology, One Shields Avenue, Tupper Hall, Coccidioidomycosis Serology Laboratory, University of California, Davis, CA, USAAbstract: Coccidioidomycosis consists of a spectrum of disease, ranging from a mild, self-limited, febrile illness to severe, life-threatening infection. It is caused by the soil-dwelling fungi, Coccidioides immitis and C. posadasii, which are present in diverse endemic areas. Climate changes and environmental factors affect the Coccidioides lifecycle and influence infection rates. The incidence of coccidioidomycosis has risen substantially over the past two decades. The vast majority of Coccidioides infections occur in the endemic zones, such as California, Arizona, Mexico, and Central America. Infections occurring outside those zones appear to be increasingly common, and pose unique clinical and public health challenges. It has long been known that elderly persons, pregnant women, and members of certain ethnic groups are at risk for severe or disseminated coccidioidomycosis. In recent years, it has become evident that persons with immunodeficiency diseases, diabetics, transplant recipients, and prisoners are also particularly vulnerable.Keywords: coccidioidomycosis, Coccidioides, epidemiology, incidence, risk factors, geography

  1. The exhibition"La France au CERN" was inaugurated by Danièle Hulin, Directrice adjointe Secteur Physique, Chimie, Sciences pour l'Ingénieur (PCSI), Ministère délégué à l'Enseignement supérieur et à la recherche.

    CERN Document Server

    Patrice Loïez

    2005-01-01

    The exhibition"La France au CERN" was inaugurated by Danièle Hulin, Directrice adjointe Secteur Physique, Chimie, Sciences pour l'Ingénieur (PCSI), Ministère délégué à l'Enseignement supérieur et à la recherche.

  2. [Eco-epidemiology: towards epidemiology of complexity].

    Science.gov (United States)

    Bizouarn, Philippe

    2016-05-01

    In order to solve public health problems posed by the epidemiology of risk factors centered on the individual and neglecting the causal processes linking the risk factors with the health outcomes, Mervyn Susser proposed a multilevel epidemiology called eco-epidemiology, addressing the interdependence of individuals and their connection with molecular, individual, societal, environmental levels of organization participating in the causal disease processes. The aim of this epidemiology is to integrate more than a level of organization in design, analysis and interpretation of health problems. After presenting the main criticisms of risk-factor epidemiology focused on the individual, we will try to show how eco-epidemiology and its development could help to understand the need for a broader and integrative epidemiology, in which studies designed to identify risk factors would be balanced by studies designed to answer other questions equally vital to public health. © 2016 médecine/sciences – Inserm.

  3. Clinical epidemiology.

    Science.gov (United States)

    Martin, S W; Bonnett, B

    1987-06-01

    Rational clinical practice requires deductive particularization of diagnostic findings, prognoses, and therapeutic responses from groups of animals (herds) to the individual animal (herd) under consideration This process utilizes concepts, skills, and methods of epidemiology, as they relate to the study of the distribution and determinants of health and disease in populations, and casts them in a clinical perspective.We briefly outline diagnostic strategies and introduce a measure of agreement, called kappa, between clinical diagnoses. This statistic is useful not only as a measure of diagnostic accuracy, but also as a means of quantifying and understanding disagreement between diagnosticians. It is disconcerting to many, clinicians included, that given a general deficit of data on sensitivity and specificity, the level of agreement between many clinical diagnoses is only moderate at best with kappa values of 0.3 to 0.6.Sensitivity, specificity, pretest odds, and posttest probability of disease are defined and related to the interpretation of clinical findings and ancillary diagnostic test results. An understanding of these features and how they relate to ruling-in or ruling-out a diagnosis, or minimizzing diagnostic errors will greatly enhance the diagnostic accuracy of the practitioner, and reduce the frequency of clinical disagreement. The approach of running multiple tests on every patient is not only wasteful and expensive, it is unlikely to improve the ability of the clinician to establish the correct diagnosis.We conclude with a discussion of how to decide on the best therapy, a discussion which centers on, and outlines the key features of, the well designed clinical trial. Like a diagnosis, the results from a clinical trial may not always be definitive, nonetheless it is the best available method of gleaning information about treatment efficacy.

  4. Epidemiological study of patients with facial trauma treated at the Antônio Targino Hospital - Campina Grande/Paraíba Estudo epidemiológico dos pacientes atendidos com trauma de face no Hospital Antônio Targino - Campina Grande/Paraíba

    Directory of Open Access Journals (Sweden)

    Josuel Raimundo Cavalcante

    2009-10-01

    Full Text Available Information contained in the present study can better explain the type of care performed in this service, which is paramount in order to plan, organize and improve medical care here. AIM: the goal of the present study was to carry out a retrospective epidemiological study concerning facial trauma from August 2006 to August 2007. MATERIALS AND METHODS: 211 charts were studied in order to collect patient data regarding the number of patients seen, gender, age, year and their origin, surgical approaches and cases. RESULTS: Among the surgical cases, facial fractures were the most prevalent (73.9%. Male patients prevailed (81.5%, in the ages between 11 and 40 years from the arid Paraíba mesoregion. The most frequent causes we motorcycle accidents, making up 64.5% of the sample, and the zygomatic-orbital complex was the most affected site. CONCLUSION: The most affected patients were males, and those from the Paraíba arid mesoregion were the ones who benefited the most from the service. Among the most frequent etiological factors we list: motorcycle accidents, physical fights and falls from one's own height.As informações contidas na presente pesquisa provêem dados para um melhor esclarecimento do tipo de atendimento realizado pelo serviço, sendo de fundamental importância para o planejamento, organização e melhoria do atendimento. OBJETIVO: Este trabalho teve como finalidade realizar um estudo epidemiológico retrospectivo dos traumas de face, no período compreendido entre agosto de 2006 a agosto de 2007. MATERIAL E MÉTODO: Foram examinados 211 prontuários e coletados dados relacionados ao número de pacientes atendidos, gênero, idade, ano e procedência, modalidades e acessos cirúrgicos realizados. RESULTADO: Dentre as modalidades cirúrgicas, as fraturas faciais foram as mais prevalentes (73,9%. Houve uma predominância de pacientes do gênero masculino (81,5%, na faixa etária compreendida entre 11 e 40 anos e oriundos da mesorregi

  5. La planificación tributaria como instrumento idóneo para maximizar los beneficios económicos: caso del subsector comercializadoras de la rana especie "catesbiana”

    OpenAIRE

    Torres Gallardo, Ana Lucía

    2016-01-01

    La presente investigación tiene como propósito aplicar la planificación tributaria como instrumento idóneo para maximizar el aprovechamiento de los beneficios e incentivos existentes en nuestro sistema tributario, aplicado al subsector ranicultor. El objetivo principal es proporcionar a los empresarios (principalmente pequeños y medianos) directrices para aprovechar los beneficios e incentivos que la ley establece, e incentivar de esta forma el emprendimiento y la asociación entre empresarios...

  6. Aspectos clínicos, epidemiológicos e patológicos da infecção natural em bovinos por Trypanosoma vivax na Paraíba Clinical, epidemiological and pathological signs of natural infection in cattle by Trypanosoma vivax in Paraíba, Brazil

    Directory of Open Access Journals (Sweden)

    Jael S. Batista

    2008-01-01

    located in the state of Paraíba, northeastern Brazil. The epidemiology, clinical signs and pathology of the disease were studied from May 2005 to November 2006. T. vivax was identified morphologically and by polymerase chain reaction test (PCR. The affected cattle presented anorexia, depression, fever, anemia, weight loss, reduction in milk production, transitory blindness, abortion and some nervous signs as nystagmus, tetany and bruxism. All cattle that presented nervous signs died. Necropsy findings were enlarged lymph and spleen, serous atrophy of the fat depots, proeminence of the splenic white pulp, hydropericardium and pericardial petechiae and ecchymoses on the epicardium. Histologically there was meningoencephalitis. The treatment of the clinical cases with diminazena aceturate was efficient with clearance of the parasite from the blood or disappearance of clinical signs in up to 2 months after the beginning of the outbreak on the two farms studied. The epidemiologic factors favoring the occurrence of the outbreak were the abundance of mechanical vectors, as tabanids and Stomoxys sp., and the introduction into the herd of cattle from farms where the disease occurred. It is suggested that the semiarid of the Brazilian Northeast is an enzootic instability region for trypanosomiasis due to its prolonged periods of drought and high temperatures, constituting during most part of the year an unfavorable environment for the development of vectors.

  7. Epidemiological methods for research with drug misusers: review of methods for studying prevalence and morbidity Métodos: epidemiológicos para pesquisa com usuários de drogas: revisão de métodos para estudo da prevalência e morbidade

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    John Dunn

    1999-04-01

    Full Text Available Epidemiological studies of drug misusers have until recently relied on two main forms of sampling: probability and convenience. The former has been used when the aim was simply to estimate the prevalence of the condition and the latter when in depth studies of the characteristics, profiles and behaviour of drug users were required, but each method has its limitations. Probability samples become impracticable when the prevalence of the condition is very low, less than 0.5% for example, or when the condition being studied is a clandestine activity such as illicit drug use. When stratified random samples are used, it may be difficult to obtain a truly representative sample, depending on the quality of the information used to develop the stratification strategy. The main limitation of studies using convenience samples is that the results cannot be generalised to the whole population of drug users due to selection bias and a lack of information concerning the sampling frame. New methods have been developed which aim to overcome some of these difficulties, for example, social network analysis, snowball sampling, capture-recapture techniques, privileged access interviewer method and contact tracing. All these methods have been applied to the study of drug misuse. The various methods are described and examples of their use given, drawn from both the Brazilian and international drug misuse literature.São descritos e discutidos os vários métodos de amostragem, de probabilidade e conveniência para estudos epidemiológicos sobre usuários de drogas, e apresentados exemplos de seu uso, com base na literatura brasileira e internacional. Os estudos epidemiológicos sobre usuários de drogas, realizados até recentemente, têm utilizado duas formas principais de amostragem: a de probabilidade e a de conveniência. A primeira tem sido utilizada quando o objetivo é apenas estimar a prevalência da condição sendo pesquisada e a segunda (conveniência quando

  8. Cervical cancer and human papillomavirus: Epidemiological evidence and perspectives for prevention Cáncer del cérvix y virus del papiloma humano: evidencia epidemiológica y perspectivas para su prevención

    Directory of Open Access Journals (Sweden)

    NUBIA MUÑOZ

    1997-07-01

    Full Text Available Cervical cancer is a major public health problem, as it is the second most common cancer in women world-wide after breast cancer. About 80% of the half a million cases estimated to occur annually in the world, occur in developing countries. The epidemiological evidence linking human papillomavirus (HPV to cervical cancer is reviewed. It is concluded that over 90% of cervical cancers can be attributed to certain HPV types. HPV 16 accounts for the highest proportion (50% followed by HPV 18 (12%, HPV 45 (8% and HPV 31 (5%. The associations with these HPV types are very b and consistent with odds ratios over 15 in all case-control studies in high- and low-risk countries for cervical cancer. However, HPV is not a sufficient cause of this malignancy; certain cofactors are necessary for a proportion of HPV persistent infections to eventually progress to cancer. These include host factors such as histocompatibilidad types and immunological response, hormonal influences and infections with other sexually transmitted agents such as Chlamydia trachomatis. In addition, results from our studies carried out in Spain and Colombia support the hypothesis that male carriers of HPV play an important role in the development of cervical cancer in their wives. The recognition of the central role of HPV in cervical cancer has far-reaching implications for the primary and secondary prevention of this malignancy. Prophylactic and therapeutic HPV vaccines are now under development and HPV typing is being integrated into screening programmes in pilot studies in a few developed countries. In developing countries, well conducted conventional screening programmes remain the best approach for the control of cervical cancer until a safe and efficient HPV vaccine can be used in the general population.El cáncer del cérvix constituye un problema importante de salud pública y es el más común en el mundo, después del de mama. Aproximadamente 80% de los 500 000 casos que se

  9. La capacidad de gobernanza de la UE para dar respuesta a la crisis económica y evaluar y prevenir las necesidades futuras del mercado de trabajo

    OpenAIRE

    Francisco González-Blanch

    2011-01-01

    La gobernanza económica es una prioridad en las políticas comunitarias especialmente hoy, ante una crisis que confiere una imprevisibilidad excepcional en el porvenir de la economía europea. El examen de las causas de la crisis ha destacado diversas debilidades del Modelo Social Europeo. Los instrumentos de gobernanza del MSE (directivas, Directrices Integradas, método abierto de coordinación, Diálogo social, aprendizaje mutuo, programas comunitarios) deben revisarse para que sean pertinentes...

  10. Sistema integrado de gestión para empresas turísticas

    Directory of Open Access Journals (Sweden)

    Alba Ligia López Rodríguez

    2009-07-01

    Full Text Available El propósito fundamental del artículo es presentar los resultados del estudio del marco de referencia teórico y práctico (primera y segunda etapa, para lograr el objetivo de investigación en una tercera etapa, la cual consiste en la formulación del modelo de un Sistema Integrado para la Gestión de Empresas Turísticas, orientado a las Mipymes articuladas en la cadena productiva como una estrategia que contribuya al desarrollo y sostenibilidad de un destino turístico de clase mundial. El proyecto se desarrolla con el método descriptivo, partiendo del análisis de la política pública del Estado colombiano, de estudios y experiencias de otros países, de directrices emanadas de organismos internacionales y de un estudio realizado en dos destinos turísticos.

  11. SISTEMA INTEGRADO DE GESTIÓN PARA EMPRESAS TURÍSTICAS

    Directory of Open Access Journals (Sweden)

    ALBA LIGIA LÓPEZ RODRÍGUEZ

    2009-01-01

    Full Text Available El propósito fundamental del artículo es presentar los resultados del estudio del marco de referencia teórico y práctico (primera y segunda etapa, para lograr el objetivo de investigación en una tercera etapa, la cual consiste en la formulación del modelo de un Sistema Integrado para la Gestión de Empresas Turísticas, orientado a las Mipymes articuladas en la cadena productiva como una estrategia que contribuya al desarrollo y sostenibilidad de un destino turístico de clase mundial. El proyecto se desarrolla con el método descriptivo, partiendo del análisis de la política pública del Estado colombiano, de estudios y experiencias de otros países, de directrices emanadas de organismos internacionales y de un estudio realizado en dos destinos turísticos.

  12. Epidemiologists working together with anthropologists: lessons from a study to evaluate the epidemiological impact of a city-wide sanitation program Los epidemiólogos y antropólogos que trabajan juntos: lecciones de un estudio para evaluar el impacto epidemiológico de un programa de saneamiento urbano Epidemiologistas e antropólogos trabalhando juntos: lições de um estudo para avaliar o impacto epidemiológico de um programa de saneamento urbano

    Directory of Open Access Journals (Sweden)

    Mauricio L. Barreto

    2013-03-01

    Full Text Available This paper discusses the role of qualitative approaches in epidemiological studies, beginning with a general discussion of epidemiological and anthropological methods. It focuses on a case study of the health impact of an environmental intervention carried out in Salvador, Bahia State, Brazil. Most of the precedent studies fields, based on primary date, use to devote little attention to the methodological and theorethical questions attached to long-term studies. Four specific aspects of this experience are highlighted: (a drawing up epidemiological study; (b construction of an observational instrument to measure hygiene habits; (c an ethnographic study that was carried out before the epidemiological study; (d observation of the effects of health intervention on health inequalities. Finally, the report details how the findings of qualitative and quantitative studies might be synthesized. It provides a critical overview of follow-up strategies, illustrated with proper examples whenever possible.En este artículo se discute el papel de los enfoques cualitativos en los estudios epidemiológicos, comenzando con una discusión general de ambos métodos. Se centra en un estudio de caso sobre el impacto en la salud de una intervención ambiental en Salvador, Bahía, Brasil. La mayoría de los estudios en esta línea, que se deriven de la fuente principal de la investigación, aporta poca discusión sobre los aspectos metodológicos y teóricos que participan en estudios a largo plazo. Cuatro aspectos específicos de esta experiencia son especialmente prominentes: (a elaboración de cuestionarios para el estudio epidemiológico; (b la construcción de un instrumento para medir los hábitos de higiene de observación; (c un estudio etnográfico que precedió a la investigación epidemiológica; (d observación de los efectos de las intervenciones sanitarias sobre las desigualdades en salud. Por último, el estudio considera en detalle cómo los resultados

  13. Epidemiology of IBD

    Science.gov (United States)

    ... IBD? Projects and Partners Data and Statistics Resources Epidemiology of the IBD Recommend on Facebook Tweet Share ... 5:1424-9. 2 Loftus EV, Jr. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental ...

  14. International Lymphoma Epidemiology Consortium

    Science.gov (United States)

    The InterLymph Consortium, or formally the International Consortium of Investigators Working on Non-Hodgkin's Lymphoma Epidemiologic Studies, is an open scientific forum for epidemiologic research in non-Hodgkin's lymphoma.

  15. Evaluation of epidemiological studies

    International Nuclear Information System (INIS)

    Breckow, J.

    1995-01-01

    The publication is intended for readers with a professional background in radiation protection who are not experts in the field of epidemiology. The potentials and the limits of epidemiology are shown and concepts and terminology of radioepidemilogic studies as well as epidemiology in general are explained, in order to provide the necessary basis for understanding or performing evaluations of epidemiologic studies. (orig./VHE) [de

  16. Ética, clínica e diretrizes: a formação do psicólogo em tempos de avaliação de cursos Ética, clínica y directrices: la formación del psicólogo en tiempos de evaluación de cursos Ethics, clinic, and directives: psychologist's qualification, in times of course assessment

    Directory of Open Access Journals (Sweden)

    João Leite Ferreira Neto

    2006-08-01

    Full Text Available O presente artigo apresenta e discute os resultados de uma pesquisa sobre a relação entre ética e clínica no contexto da formação universitária do psicólogo. A clínica é entendida como um dispositivo ético de subjetivação, a partir da análise de conceitos extraídos de Lacan e Foucault. O trabalho de campo foi realizado numa instituição particular de ensino superior, com ênfase em sua clínica-escola. Os dados obtidos são colocados em um diálogo crítico com a proposta de Diretrizes Curriculares para os cursos de Psicologia. Salienta-se a importância da ética entendida como conjunto de "práticas de si" na formação geral do psicólogo, ainda que esta ênfase não seja contemplada pelas Diretrizes. Considera-se relevante que a dimensão ética da clínica "psi" esteja presente de modo transversal, não segmentado, na formação geral do psicólogo.El presente artículo presenta y discute los resultados de una investigación sobre la relación entre ética y clínica en el contexto de la formación universitaria del psicólogo. La clínica es entendida como un dispositivo ético de subjetivación, a partir del análisis de conceptos extraídos de Lacan y Foucault. El trabajo de campo fue realizado en una institución privada de enseñanza superior, con énfasis en su clínica-escuela. Los datos obtenidos son puestos en un diálogo crítico con la propuesta de Directrices Curriculares para los cursos de Psicología. Se resalta la importancia de la ética entendida como conjunto de "prácticas de sí" en la formación general del psicólogo, aunque este énfasis no sea contemplado por las Directrices. Se considera relevante que la dimensión ética de la clínica "psi" esté presente de modo transversal, no segmentado, en la formación general del psicólogo.The current article presents and discusses the results of a research about the relation between Ethics and Clinic in the context of the university qualification granted to

  17. Ensino da enfermagem psiquiátrica/saúde mental: sua interface com a Reforma Psiquiátrica e diretrizes curriculares nacionais La enseñanza de la enfermería psiquiátrica/salud mental: su conexión con la Reforma Psiquiátrica y las directrices curriculares nacionales Teaching psychiatric nursing/mental health: its interface with the Brazilian Psychiatric Reform and national curriculum guidelines

    Directory of Open Access Journals (Sweden)

    Josicelia Dumêt Fernandes

    2009-12-01

    Full Text Available Estudo teórico acerca do processo de formação em Enfermagem Psiquiátrica e Saúde Mental, frente às crescentes mudanças no mundo globalizado e seu acelerado processo de modernização científica e tecnológica. Objetiva discutir o fazer pedagógico no ensino da Enfermagem Psiquiátrica e Saúde Mental, e sua interface com os princípios da Reforma Psiquiátrica e das Diretrizes Curriculares Nacionais dos Cursos de Graduação em Enfermagem. Para sua sustentação teórica, adota como referência alguns construtos da Reforma Psiquiátrica e das Diretrizes Curriculares Nacionais do Curso de Graduação em Enfermagem, e sua relação com fatores constituintes do fazer pedagógico na Enfermagem Psiquiátrica e Saúde Mental. Evidencia que não basta apontar questões técnicas relativas a conteúdos e ensino, procedimentos didáticos, métodos e técnicas pedagógicas; é necessário superar desafios e implementar as mudanças, pautando-se numa nova perspectiva, e ousando colocar em questão a natureza do saber e das práticas institucionais psiquiátricas.Estudio teórico acerca del proceso de formación en Enfermería Psiquiátrica y Salud Mental, frente a los crecientes cambios en el mundo globalizado y su acelerado proceso de modernización científica y tecnológica. Objetiva discutir el quehacer pedagógico en la enseñanza de Enfermería Psiquiátrica y Salud Mental, y su conexión con los principios de la Reforma Psiquiátrica y de las Directrices Curriculares Nacionales de los Cursos de Graduación en Enfermería. Para su sustentación teórica, adopta como referencia algunos constructos de la Reforma Psiquiátrica y de las Directrices Curriculares Nacionales del Curso de Graduación en Enfermería, y su relación con factores constituyentes del quehacer pedagógico en la Enfermería Psiquiátrica y Salud Mental. Evidencia que no basta apuntar cuestiones técnicas relativas a contenidos y enseñanza, procedimientos didácticos, m

  18. en epidemiología

    Directory of Open Access Journals (Sweden)

    Ana V. Diez Roux

    2008-01-01

    Full Text Available La epidemiología sociocultural se caracteriza por la integración de procesos sociales, culturales, económicos y políticos con procesos biológicos en el estudio de los determinantes de la salud. Por definición, esto implica la consideración de determinantes especificados a múltiples niveles, desde los genes hasta las características de la sociedad en su totalidad. En este artículo se analizan diversos problemas metodológicos que surgen en epidemiología (y en las ciencias sociales en general por la presencia de múltiples niveles de organización que pueden ser relevantes para entender las causas de la salud y la enfermedad. Se subraya la necesidad de investigar conjuntamente (o de integrar determinantes de la salud definidos a distintos niveles. El artículo concluye con un examen de las implicaciones de la presencia de múltiples niveles para el estudio de los determinantes sociales o culturales de la salud.

  19. Epidemiologia dos acidentes ofídicos notificados pelo Centro de Assistência e Informação Toxicológica de Campina Grande (Ceatox-CG, Paraíba Epidemiologic profile of snakebites reported by the Poison Information Center of Campina Grande, Paraíba

    Directory of Open Access Journals (Sweden)

    Josiverton de Carvalho Lemos

    2009-03-01

    Full Text Available Os acidentes causados por animais peçonhentos ainda constituem problema de Saúde Pública no Brasil. Embora a produção e a distribuição dos soros no país encontrem-se estabilizadas, há problemas relacionados à notificação de acidentes deste tipo em várias regiões. Considerando esta realidade, foi realizado um estudo transversal entre janeiro e dezembro de 2005, utilizando documentação indireta sobre os acidentes ofídicos ocorridos em Campina Grande e 80 municípios adjacentes à região, com o objetivo de conhecer o perfil epidemiológico e clínico deste tipo de caso. Todos os pacientes atendidos tiveram diagnóstico médico de acidente por serpentes realizado pelo Centro de Atendimento Toxicológico de Campina Grande (Ceatox-CG. Os dados foram coletados através da ficha de notificação do Sinan (Sistema Nacional de Notificação de Agravo do Ministério da Saúde. Para análise dos dados, foi utilizada estatística descritiva e os dados foram tabulados no programa Microsoft Excel 2003. Dos 1.443 atendimentos no Centro, 737 foram causados por animais peçonhentos e, destes, 277 foram provocados por serpentes peçonhentas e não peçonhentas. Os acidentes predominaram no sexo masculino, na faixa etária de 10 a 29 anos, principalmente em agricultores na zona rural, entre maio e novembro de 2005. O gênero Bothrops foi responsável pelo maior número de casos (71,5%, e as extremidades superior e inferior do corpo foram os locais de maior predominância de ataques. Na extremidade inferior, foi atingido principalmente o pé. Em relação à gravidade, foram mais frequentes os acidentes classificados como leves causados pelo gênero Bothrops e apenas um paciente evoluiu para óbito. A média do tempo de atendimento, em horas, foi superior a 12 horas nos acidentes considerados graves, causados pelos gêneros Bothrops e Crotalus. Nossos resultados concordam com o perfil epidemiológico nacional dos acidentes ofídicos, atingindo com

  20. Vigilancia epidemiológica para la prevención y el control de la violencia en las ciudades Epidemiologic surveillance for the prevention and control of urban violence

    Directory of Open Access Journals (Sweden)

    Alberto Concha-Eastman

    1999-04-01

    Full Text Available Violence prevention policies should be based on information, follow-up, research, and analysis, all of which increase the chances of success and make it easier to evaluate interventions. This implies, in turn, that there is a need to create surveillance, research, and prevention models for violence within the sphere of public health and epidemiology, a task that constitutes an integral part of the Pan American Health Organization's Regional Plan of Action Health and Violence. This article describes the objectives of epidemiologic surveillance systems and explains their purpose and scope, along with the barriers that stand in the way of their implementation. It also examines a number of variables and their definitions, the types of analyses and reports that should be generated, and the decisions that can be made on the basis of these reports. Finally, it discusses ethical criteria and describes the experiences of the program known as Desarrollo, Seguridad y Paz (DESEPAZ in Cali and Santa Fe de Bogota, Colombia, where an epidemiologic surveillance system against violence has been implemented.

  1. Software educativo para enfermería

    Directory of Open Access Journals (Sweden)

    Mac Gaul de Jorge, Marcia Ivonne

    2009-01-01

    Full Text Available El presente trabajo relata la experiencia de investigación del proyecto investigación del proyecto Nº 1531 del CIUNSa, "Software Educativo para Enfermería del Adulto". El equipo integra a enfermeras, quienes en el año 2003 elaboraron un material que responde a la realidad epidemiológica de nuestro país, marcadamente diferente a textos clásicos provenientes de otras regiones del mundo. Convencidos que las universidades deben dar respuestas a los problemas regionales, se están desarrollando materiales educativos que, aprovechan las ventajas que la Informática brinda (altamente interactivos y que pueden actualizarse permanentemente. Esta investigación está finalizando su etapa diagnóstica, la cual posee dos objetivos específicos para el desarrollo del producto software: uno tendiente a indagar las competencias de los alumnos de Ciencias de la Salud con relación al uso de materiales educativos informatizados; el otro, modelar el sistema informático del cual serán usuarios los alumnos y docentes, para lo cual se están realizando actividades de Ingeniería de Requerimientos que permitan establecer el contexto en el que se utilizará el software desarrollado. Creemos que el estudio diagnóstico culminado sitúa a nuestros alumnos en la misma sintonía de los desarrolladores. Sus expectativas por un recurso efectivamente didáctico coinciden con nuestras directrices de diseño.

  2. Viability of using multidimensional graphics in epidemiological data analysis: case study with respiratory diseases = Viabilidade do uso gráfico multidimensional para análise de dados epidemiológicos: estudo de caso com doenças respiratórias

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    Elisa Norberto Ferreira Santos

    2012-10-01

    Full Text Available The statistical methodology to be used in epidemiological data analysis is extremely important for obtaining reliable and plausible results that can be interpreted in the epidemiological context. In order to carry out a case study about the incidence of the main respiratory diseases in some cities with different climatic seasons, the present work aimed at studying the viability for applying the multidimensional graphic technique known as “h-plot” to identify the main variables that resulted in a higher contribution to the data dispersal. In accordance with the results obtained and discussed, we state that the h-plot graphics are viable to be applied as an alternative method as regards to the identification and collection of the variables.A metodologia estatística a ser utilizada na análise dos dados epidemiológicos é de suma importância para que os resultados obtidos sejam confiáveis e plausíveis de serem interpretados no contexto epidemiológico. Com o propósito de realizar um estudo de caso sobre a incidência das principais doenças respiratórias em algumas cidades com estações climáticas bem diferenciadas, o presente trabalho tem por objetivo estudar a viabilidade da aplicação da técnica gráfica multidimensional conhecida por “h-plot” para identificar principais variáveis que resultaram em maior contribuição na dispersão dos dados. Em consonância com os resultados obtidos e discutidos neste trabalho, recomendou-se que os gráficos h-plots são viáveis de serem aplicados como um método alternativo no que se refere à identificação e agrupamento das variáveis.

  3. Las nuevas tendencias en gestión municipal : Propuesta de un modelo de administración turística para el Municipio de La Plata, provincia de Buenos Aires

    OpenAIRE

    Molinari, Gloria Edith

    2012-01-01

    Con el presente trabajo propongo la factibilidad de aplicar un modelo de gestión comúnmente utilizado en las organizaciones privadas a los organismos públicos, en este caso dedicados a la actividad turística. Nos concentraremos en la gestión Municipal del turismo en la ciudad de La Plata. Para ello, utilicé el Manual de Directrices de Municipios Turísticos de la SECTUR, aplicado a la Dirección de Turismo de la Municipalidad de La Plata, con el fin de evaluar diferentes aspectos de l...

  4. Low dose epidemiology

    International Nuclear Information System (INIS)

    Tirmarche, M.; Hubert, P.

    1992-01-01

    Actually, epidemiological studies have to establish if the assessment of cancer risk can be verified at low chronic radiation doses. The population surveillance must be very long, the side effects and cancers of such radiation appearing much later. In France, this epidemiological study on nuclear workers have been decided recently. Before describing the experiment and french projects in epidemiology of nuclear workers, the authors present the main english and american studies

  5. Aderência de cursos de graduação em enfermagem às diretrizes curriculares nacionais na perspectiva do sistema único de saúde Adherencia de cursos de graduación en enfermería a las directrices curriculares nacionales en la perspectiva del sistema único de salud Tack in the nursing graduate courses according to the curriculum national guidelines in the perspective of the sistema único de saúde

    Directory of Open Access Journals (Sweden)

    Josicelia Dumêt Fernandes

    2013-03-01

    Full Text Available O estudo objetivou apreender, nas percepções de discentes de cursos de graduação em enfermagem, o registro da coerência didático-pedagógica desses cursos com as Diretrizes Curriculares Nacionais do Curso de Graduação em Enfermagem, na perspectiva do Sistema Único de Saúde (SUS. Estudo qualitativo, de caráter exploratório descritivo, que teve como cenário quatro cursos de graduação em enfermagem de uma cidade do nordeste do Brasil. Os sujeitos foram discentes que, por meio de entrevistas, indicaram que a articulação entre as instituições formadoras e o SUS se dá no momento da realização das práticas, assim como no ensino dos princípios e diretrizes do SUS, nos componentes curriculares e, ainda, nas atividades desenvolvidas nos projetos de pesquisa e extensão; outros indicaram, também, que não percebem tal articulação no seu processo formativo. O resultado do estudo revelou a necessidade de fortalecimento do processo de formação do enfermeiro nos cenários de práticas na rede de serviços de saúde.El estudio tiene como objetivo la comprensión, la percepción de los alumnos de los cursos de licenciatura en enfermería, el registro de la coherencia didáctica y pedagógica de estos cursos con las Directrices Curriculares Nacionales para la Graduación en Enfermería, en la perspectiva del Sistema Único de Salud (SUS. Estudio cualitativo y exploratorio, descriptivo, teniendo como escenario cuatro cursos de graduación en enfermería en una ciudad del noroeste de Brasil. Los sujetos eran estudiantes que, a través de entrevistas, indicaron que el vínculo entre las instituciones de formación y el SUS se lleva a cabo en el momento de la aplicación de prácticas, así como la enseñanza de los principios y directrices del SUS en los componentes del plan de estudios y también las actividades en los proyectos de investigación y extensión, otros han señalado, también, que no se dan cuenta de esta vinculación en

  6. Technology evaluation of a USA-Mexico health information system for epidemiological surveillance of Mexican migrant workers Evaluación tecnológica de un sistema de información de salud mexicano-estadounidense para la vigilancia epidemiológica de los trabajadores itinerantes mexicanos

    Directory of Open Access Journals (Sweden)

    Héctor Eduardo Velasco-Mondragón

    2000-03-01

    prevention, and organization of health care services for migrant workers in both Mexico and the United States. Despite the unprecedented success and potential bilateral benefits demonstrated by this project, serious structural and organizational deficits in the public health systems of both countries must be addressed before epidemiological surveillance can be achieved binationally.De 1994 a 1996, algunas organizaciones federales, estatales y no gubernamentales en México y los Estados Unidos de América han creado y puesto en marcha un Sistema de Información de Salud Binacional para la Vigilancia Epidemiológica de trabajadores itinerantes mexicanos. El sistema permitió el intercambio de información epidemiológica entre el estado de Guanajuato en México y el estado de Pensilvania en los Estados Unidos, en lo referente a la detección, prevención y tratamiento de casos, mediante la investigación de contactos en común y el manejo de personas con enfermedades transmisibles. La población destinataria se compuso de trabajadores itinerantes que viajaban entre Guanajuato y Pensilvania para trabajar principalmente en la industria de los hongos, y de sus compañeras sexuales en las comunidades mexicanas de donde provenían. Se montaron módulos de información sanitaria computadorizados para los itinerantes en Guanajuato y Pensilvania. Los datos sobre los pacientes y la vigilancia epidemiológica se codificaban y enviaban por la vía electrónica de un módulo a otro mediante el sistema de comunicaciones WONDER, perteneciente a los Centros para el Control y la Prevención de Enfermedades de los Estados Unidos. La evaluación del Sistema de Información de Salud Binacional entre Guanajuato y Pensilvania reveló que las barreras que más obstaculizan la vigilancia y el control epidemiológicos en el ámbito binacional son las siguientes: a la falta de comunicación entre los dos países; b la interrupción de la atención médica con motivo de la migración; c la poca

  7. Breast Cancer Epidemiology in Puerto Rico

    Science.gov (United States)

    2013-06-30

    Cancer Research jointly (presented by the Cancer Forum and the Latino Caucus); Impact of Social Determinants on Cancer Morbidity and Mortality and...Epidemiology b. Latino Cancer Research jointly (presented by the Cancer Forum and the Latino Caucus) c. Impact of Social Determinants on Cancer...de este estudio. Este estudio no fue disefiado para tratar sus problemas de salud. Sin embargo, su participacion en este estudio es muy importante

  8. Sostenibles legislación: directrices para incorporar los conceptos de sostenibilidad en el código de edifícios en Vitória/ES

    Directory of Open Access Journals (Sweden)

    Érika da Cunha Victor Souza

    2015-12-01

    Full Text Available This article aims to examine the legal aspects of sustainable construction proposing guidelines for incorporating sustainability concepts in the Code of public works and construction of the Vitória-ES. In the global context, sustainability is evident, reinforcing the concern about the impact generated by man to the environment directly affecting the economy, society and the planet’s future, so the importance of environmental preservation and the efficient use of natural resources (water, air, energy, materials etc.. In this sense the role of legislation is important, since the goal of the code works in the municipalities is to ensure minimum conditions of environmental comfort in the deployment of any building to be built in the city. The hypothesis is that the legislation needs to be revised and the goal is to adjust it by inserting sustainability concepts. The methodology is based on literature search applied to the subject. We conclude that the Government should contribute more effectively to the reconstruction of the cities scene, playing their role through legal instruments, more effective and active way for both construction of new buildings, the renovation and adaptation of existing ones.

  9. Communications Received from Certain Member States Regarding Guidelines for the Export of Nuclear Material, Equipment and Technology; Comunicaciones recibidas de ciertos Estados Miembros relativas a las directrices para la exportacion de materiales, equipos y tecnologia nucleares

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-12

    The Director General of the International Atomic Energy Agency has received Notes Verbales, dated 1 December 2005, from the Resident Representatives to the Agency of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Czech Republic, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, New Zealand, Poland, Portugal, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, relating to the export of nuclear material, equipment and technology [Spanish] El Director General del Organismo Internacional de Energia Atomica ha recibido notas verbales de fecha 1 de diciembre de 2005 de los Representantes Permanentes ante el Organismo de Alemania, Argentina, Australia, Austria, Belarus, Belgica, Brasil, Bulgaria, Canada, China, Croacia, Eslovenia, Espana, Estados Unidos de America, Finlandia, Francia, Grecia, Hungria, Irlanda, Italia, Japon, Letonia, Lituania, Luxemburgo, Malta, Nueva Zelandia, Paises Bajos, Polonia, Portugal, Reino Unido de Gran Bretana e Irlanda del Norte, Republica Checa, Republica de Corea, Sudafrica, Suecia, Suiza, Turquia y Ucrania relativas a la exportacion de materiales, equipo y tecnologia nucleares.

  10. Sustentabilidad en espacios colectivos de barrios vulnerables: Lineamientos para una política de espacios públicos, directrices de gestión, diseño y mantenimiento.

    Directory of Open Access Journals (Sweden)

    Luis Valenzuela

    2010-01-01

    The current discussion on housing policy focuses on reducing the negative consequences of residential segregation of the poorest households. However, the design, construction, quality and maintenance of the collective space have failed to improve despite various programs that have been applied since the 1990s. Therefore, it is proposed to generate three-dimensional conceptual guidelines to promote local management capacity for collective affairs, encourage community involvement processes in public spaces and, pursuing environmental sustainability criteria and maintenance costs for the proposals. The dimensions of management, environment and emerging community-based intervention review of experiences as they were visited Peñalolén initiatives and Maipú. Based on these cases, the proposal considers local government as the articulators of the management of these spaces, thus enhancing its ability to link with the community, points for good design and responsibility for the maintenance of these spaces.

  11. Selección del paciente para cirugía refractiva: actualización

    Directory of Open Access Journals (Sweden)

    Iramis Miranda Hernández

    Full Text Available Se realiza una búsqueda de la literatura más actualizada de los últimos cinco años enfocada en publicaciones de expertos y basada principalmente en una revisión realizada recientemente en la revista Current Opinion in Ophthalmology por un grupo de investigadores de la Universidad de Baltimore, Maryland (EE.UU. sobre las contraindicaciones actuales de la cirugía refractiva. La Academia Americana de Oftalmología publica periódicamente directrices de patrones de práctica para la cirugía refractiva láser. El propósito de esta revisión es proporcionar una actualización sobre las contraindicaciones actuales y los detalles específicos relacionados con la cirugía refractiva láser.

  12. The contribution of epidemiology

    NARCIS (Netherlands)

    Brandt, P. van den; Voorrips, L.; Hertz-Picciotto, I.; Shuker, D.; Boeing, H.; Speijers, G.; Guittard, C.; Kleiner, J.; Knowles, M.; Wolk, A.; Goldbohm, A.

    2002-01-01

    Epidemiologic studies directly contribute data on risk (or benefit) in humans as the investigated species, and in the full food intake range normally encountered by humans. This paper starts with introducing the epidemiologic approach, followed by a discussion of perceived differences between

  13. As Diretrizes Curriculares Nacionais para o Ensino Médio e as proposições sobre trabalho, ciência, tecnologia e cultura reflexões necessárias

    Directory of Open Access Journals (Sweden)

    Monica Ribeiro da Silva

    2014-01-01

    Full Text Available El estudio analiza los sentidos que adquieren el trabajo, la ciencia, la cul - tura y la tecnología en la sociedad actual y problematiza, a partir de los referenciales de la Teoría Crítica de la Sociedad, la proposición de esos elementos en los textos que definen Directrices Curriculares Nacionales para la Enseñanza Media. La indagación que motivó el análisis dice respecto a la posibilidad de concreción de las intenciones enunciadas en las directrices, a saber, las de una educación que apunta a la producción de la autonomía intelectual y moral de los individuos. El camino para la discusión anunciada se delineó al tomar obras de Theodor Adorno, Max Horkheimer and Hebert Marcuse en las cuales los autores reflexionan sobre la tecnología, la ciencia, la cultura y el trabajo y las interfaces posibles entre estos y los procesos formativos. Las conclusiones apuntan en la dirección de que esas propuestas no se deben tomar de forma instrumental para evitar que sufran un vaciamiento de sentido y pierdan, así, su potencialidad.

  14. Consommation d’alcool et lignes directrices pour la consommation d’alcool à faible risque chez les adultes : une analyse transversale de l’Alberta’s Tomorrow Project

    Directory of Open Access Journals (Sweden)

    Darren R. Brenner

    2017-01-01

    Full Text Available Introduction : La consommation modérée ou élevée d’alcool constitue un facteur de risque de mortalité toutes causes confondues et de cancer. Nous disposons de données transversales grâce aux enquêtes nationales, mais jusqu'à présent aucunes données sur la consommation d’alcool en Alberta n'étaient disponibles pour une grande cohorte prospective. Notre objectif est de définir, à la lumière des lignes directrices de prévention du cancer, les niveaux de consommation d’alcool des adultes ayant pris part à l’Alberta’s Tomorrow Project. Nous avons également analysé les liens entre la consommation d’alcool et certains autres comportements à risque, en particulier à risque élevé. Méthodologie : Entre 2001 et 2009, 31 072 hommes et femmes de 35 à 69 ans ont participé à l’Alberta’s Tomorrow Project, une grande étude de cohorte provinciale. Des données concernant la consommation d’alcool dans les 12 derniers mois ont été obtenues pour 26 842 participants ayant répondu à des questionnaires autoadministrés sur la santé et sur le mode de vie. Nous avons effectué des analyses transversales sur la consommation d’alcool quotidienne et les lignes directrices de prévention du cancer en matière de consommation d’alcool en lien avec des facteurs sociodémographiques. Nous avons aussi examiné la prévalence combinée de la consommation d’alcool, du tabagisme, de l’obésité et de diverses comorbidités. Résultats : Environ 14 % des hommes et 12 % des femmes ont déclaré consommer davantage d’alcool que ce que préconisent les recommandations en matière de prévention du cancer. Une consommation plus importante d’alcool a été rapportée chez les plus jeunes, les citadins, les personnes à revenu plus élevé et celles consommant davantage de viande rouge. En outre, le volume de consommation quotidienne d’alcool était positivement associé au tabagisme, tant chez les hommes que chez les femmes

  15. Formacion en valores: una alternativa para construir ciudadania

    Directory of Open Access Journals (Sweden)

    María Graciela Calle Márquez

    2007-01-01

    Full Text Available El breve recorrido histórico con que se inicia este artículo, sirve como punto de partida para superar etapas y mejorar la Educación en valores, recuperar aquellos que son indispensables en la construcción de la ciudadanía, conocer y defender las libertades fundamentales de creencia, expresión, publicación, reunión, manifestación o protesta civilizada y derecho de petición. La formación ciudadana tiene como directrices y coordenadas: la dignidad personal, la libertad y la justicia entre otros valores. Sin perder de vista los modelos axiológicos del viejo continente, se reflexiona sobre el pensamiento ético latinoamericano y sus inmensas posibilidades en la construcción de una persona nueva con valores esencialmente humanos, lo cual sólo se alcanza mediante la educación para la libertad, el desarrollo de potencialidades ético-morales que propicien una formación auténtica; es así como la ética y la axiología en América Latina, se enriquecen con las propuestas relevantes de los expertos, que apuntan a una educación en valores de acuerdo con el ser y la idiosincrasia latinoamericanos.

  16. Indicação de cintilografia de perfusão do miocárdio para a detecção de doença arterial coronariana, baseada em evidências ergométricas e clínico-epidemiológicas Indication of myocardial perfusion scintigraphy for coronary artery disease detection based on clinical-epidemiological and treadmill test evidences

    Directory of Open Access Journals (Sweden)

    Paulo Schiavom Duarte

    2006-10-01

    Full Text Available OBJETIVO: Avaliar quando se devem realizar exames de cintilografia de perfusão do miocárdio (CPM, baseando-se em informações objetivas obtidas do teste ergométrico e da análise dos fatores clínico-epidemiológicos para doença arterial coronária (DAC. MÉTODOS: Foram submetidos a CPM 2.100 pacientes que foram classificados segundo o resultado da cintilografia, do escore de Duke e de escore clínico-epidemiológico, baseado em Framingham. Os pacientes com cintilografia positiva foram acompanhados a fim de definir se os resultados eram verdadeiros positivos. Foram utilizadas receiver operating characteristic (ROC curvas para definir a eficiência e os melhores pontos de corte dos escores de Duke e clínico-epidemiológico, na seleção dos pacientes que deveriam ser submetidos a cintilografia. RESULTADOS: Observou-se que, restringindo a solicitação da cintilografia a pacientes com escore de Duke abaixo de 7,5 e/ou escore clínico-epidemiológico acima de 4, deixaríamos de realizar cerca de 50% dos exames com riscos mínimos de perda de diagnóstico. CONCLUSÃO: A utilização do escore de Duke e de escore clínico-epidemiológico para orientar a solicitação da CPM pode diminuir expressivamente o número de exames desnecessários.OBJECTIVE: To establish when the myocardial perfusion scintigraphy (MPS should be performed based on well-defined information obtained from treadmill test results and clinical-epidemiological parameters for coronary artery disease (CAD. METHODS: 2,100 patients who underwent MPS were classified according to the results of scintigraphy, the Duke score and a clinical-epidemiological score based on Framingham study. The patients with positive results on MPS were followed to define whether the results were true positives. Receiver operating characteristic (ROC curves were used to establish the efficiency and the best Duke and clinical-epidemiological scores to define patients that should be submitted to

  17. WHO - IPHECA: Epidemiological aspects

    International Nuclear Information System (INIS)

    Souchkevitch, G.

    1996-01-01

    In May 1991 the World Health Assembly endorsed the establishment of the International Programme on the Health Effects of the Chernobyl Accident (IPHECA) under the auspices of WHO. Five pilot projects have been carried out within IPHECA in the study territories of Belarus, Russian Federation and Ukraine in a period from 1991 to 1994. This pilot projects dealt with the detection and treatment of leukaemia and related diseases (Haematology Project), thyroid disorders (Thyroid project), brain damage during exposure 'in-utero' (Brain Damage 'in-Utero' project) and with the development of the Chernobyl registries (Epidemiological Registry Project). A fifth pilot project on oral health was performed only in Belarus. Epidemiological investigations have been an important component of all IPHECA pilot projects. Within 'Epidemiological Registry' Project such investigations have been the principal activity. But with respect to other IPHECA projects it was carried out in addition to main objectives relating to medical monitoring, early diagnosis and treatment of specific diseases included in project protocols. To support the epidemiological investigations within IPHECA, WHO supplied 41 computers in Belarus, Russian Federation and Ukraine and provided training for specialists from these countries in internationally recognized centres. The training programmes and host countries were as follows: standardization of epidemiological investigations (United Kingdom), radiation epidemiology (Russia), development of software (United Kingdom), principles of epidemiological investigations (The Czech Republic), cohort investigations (Japan)

  18. WHO - IPHECA: Epidemiological aspects

    Energy Technology Data Exchange (ETDEWEB)

    Souchkevitch, G [World Health Organization, Geneva (Swaziland)

    1996-07-01

    In May 1991 the World Health Assembly endorsed the establishment of the International Programme on the Health Effects of the Chernobyl Accident (IPHECA) under the auspices of WHO. Five pilot projects have been carried out within IPHECA in the study territories of Belarus, Russian Federation and Ukraine in a period from 1991 to 1994. This pilot projects dealt with the detection and treatment of leukaemia and related diseases (Haematology Project), thyroid disorders (Thyroid project), brain damage during exposure 'in-utero' (Brain Damage 'in-Utero' project) and with the development of the Chernobyl registries (Epidemiological Registry Project). A fifth pilot project on oral health was performed only in Belarus. Epidemiological investigations have been an important component of all IPHECA pilot projects. Within 'Epidemiological Registry' Project such investigations have been the principal activity. But with respect to other IPHECA projects it was carried out in addition to main objectives relating to medical monitoring, early diagnosis and treatment of specific diseases included in project protocols. To support the epidemiological investigations within IPHECA, WHO supplied 41 computers in Belarus, Russian Federation and Ukraine and provided training for specialists from these countries in internationally recognized centres. The training programmes and host countries were as follows: standardization of epidemiological investigations (United Kingdom), radiation epidemiology (Russia), development of software (United Kingdom), principles of epidemiological investigations (The Czech Republic), cohort investigations (Japan)

  19. Basic concepts of epidemiology

    International Nuclear Information System (INIS)

    Savitz, D.A.

    1984-01-01

    Epidemiology can be defined simply as the science of the distribution and determinants of disease in human populations. As a descriptive tool, epidemiology can aid health care service providers, for example, in allocation of resources. In its analytic capacity, the epidemiologic approach can help identify determinants of disease through the study of human populations. Epidemiology is primarily an observational rather than experimental methodology, with corresponding strengths and limitations. Relative to other approaches for assessing disease etiology and impacts of potential health hazards, epidemiology has a rather unique role that is complementary to, but independent of, both basic biologic sciences and clinical medicine. Experimental biologic sciences such as toxicology and physiology provide critical information on biologic mechanisms of disease required for causal inference. Clinical medicine often serves as the warning system that provides etiologic clues to be pursued through systematic investigation. The advantage of the epidemiologic approach is its reliance on human field experience, that is, the real world. While laboratory experimentation is uniquely well suited to defining potential hazards, it can neither determine whether human populations have actually been affected nor quantify that effect. Building all the complexities of human behavior and external factors into a laboratory study or mathematical model is impossible. By studying the world as it exists, epidemiology examines the integrated, summarized product of the myriad factors influencing health

  20. Epidemiology: Then and Now.

    Science.gov (United States)

    Kuller, Lewis H

    2016-03-01

    Twenty-five years ago, on the 75th anniversary of the Johns Hopkins Bloomberg School of Public Health, I noted that epidemiologic research was moving away from the traditional approaches used to investigate "epidemics" and their close relationship with preventive medicine. Twenty-five years later, the role of epidemiology as an important contribution to human population research, preventive medicine, and public health is under substantial pressure because of the emphasis on "big data," phenomenology, and personalized medical therapies. Epidemiology is the study of epidemics. The primary role of epidemiology is to identify the epidemics and parameters of interest of host, agent, and environment and to generate and test hypotheses in search of causal pathways. Almost all diseases have a specific distribution in relation to time, place, and person and specific "causes" with high effect sizes. Epidemiology then uses such information to develop interventions and test (through clinical trials and natural experiments) their efficacy and effectiveness. Epidemiology is dependent on new technologies to evaluate improved measurements of host (genomics), epigenetics, identification of agents (metabolomics, proteomics), new technology to evaluate both physical and social environment, and modern methods of data collection. Epidemiology does poorly in studying anything other than epidemics and collections of numerators and denominators without specific hypotheses even with improved statistical methodologies. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Uso de los datos de plumbemia para evaluar y prevenir el envenenamiento infantil por plomo en Latinoamérica Use of blood lead data in epidemiological studies to assess and prevent childhood lead poisoning in Latin America

    Directory of Open Access Journals (Sweden)

    Isabelle Romieu

    2003-01-01

    Full Text Available La exposición al plomo es una amenaza seria para la salud de los niños, que se encuentra ampliamente distribuida en la Región de América Latina. Los funcionarios de salud pública necesitan identificar fuentes de exposición al plomo, así como sus efectos en la salud, para poder diseñar, implantar y evaluar las actividades preventivas y de control. Para evaluar la magnitud del problema del plomo es necesario definir tres elementos clave: a las fuentes potenciales de exposición, b los indicadores que se utilizarán para evaluar los efectos en la salud y la exposición en el medio ambiente, y c las estrategias de muestreo de la población en riesgo. Se pueden utilizar varias estrategias con el fin de seleccionar la población blanco dependiendo de los objetivos del estudio, el tiempo límite y los recursos disponibles. Si el objetivo es evaluar la magnitud y las fuentes del problema pueden emplearse los siguientes métodos de muestreo: a el muestreo al azar basado en la población; b el muestreo al azar basado en las facilidades dentro de los hospitales, las guarderías o las escuelas; c el muestreo objetivo de los grupos de alto riesgo; d el muestreo de conveniencia (de voluntarios, y e el reporte de los casos (éste puede conducir a la identificación de las poblaciones en riesgo, además de las fuentes de exposición. Para todos los diseños de muestreo, la información debe incluir tanto el uso de un cuestionario para el informe general de los participantes y de las fuentes potenciales locales de exposición, como la recolección de las muestras biológicas. En la interpretación de los datos se debe considerar el tipo de muestreo utilizado, el porcentaje de falta de respuesta y los factores que pueden influir en las mediciones del plomo en sangre, como la edad y la variación de la temporada. Las mediciones del plomo en la sangre se deben integrar dentro de una estrategia general para la prevención de toxicidad.Exposure to lead is a

  2. Epidemiology and Radiation Protection

    International Nuclear Information System (INIS)

    1987-01-01

    Epidemiology aims at providing direct evidence of the long term health effects in humans due to potentially dangerous exposures to various nuisance agents, including ionising radiation. Inappropriate interpretation and use of the results of epidemiological studies may result in inaccurate assessments of the risks associated with radiation exposure. This report presents the proceedings of a Workshop organised by the NEA to create an opportunity for epidemiologists and radiation protection specialists to exchange their experiences and views on the problems of methodology in epidemiological research and on the application of its results to the assessment of radiation risks

  3. Estandarización de la obtención de amplificados del genoma del virus de la rabia para su uso en estudios de epidemiología molecular

    Directory of Open Access Journals (Sweden)

    Andrés Páez

    2002-03-01

    Full Text Available Con el fin de perfeccionar el diagnóstico y la tipificación del virus de la rabia en Colombia, el Laboratorio Nacional de Referencia del Instituto Nacional de Salud estandarizó técnicas para amplificar un fragmento de ADN complementario (ADNc a una fracción de 902 nucleótidos seleccionados del ARN del virus de la rabia. La fracción mencionada contiene secuencias que codifican para los aminoácidos 447-525 de la glicoproteína y 1-35 de la proteína L. Además, contiene la región intergénica no codificante conocida como Pseudogen Psi. Las técnicas estandarizadas consistieron en: 1 amplificación biológica mediante reaislamiento del virus en ratón ICR, 2 extracción del ARN total a partir del cerebro del ratón infectado, y 3 amplificación molecular utilizando la técnica de transcripción reversa y reacción en cadena de la polimerasa (RT-PCR para obtener el ADNc. La muestra del estudio constó de 30 cepas de virus de rabia obtenidas originalmente de 30 caninos y tomadas del banco del Laboratorio de Virología. Por su simplicidad, la metodología descrita en este estudio presenta grandes ventajas sobre las técnicas descritas en anteriores estudios. La tecnología propuesta es un complemento preciso de las técnicas de diagnóstico de la rabia; además, se aplica a la identificación de relaciones filogenéticas de diversos aislamientos y, por ende, se utiliza en la identificación de las dinámicas de transmisión y difusión geográfica del virus rábico.

  4. Cancer Epidemiology Cohorts

    Science.gov (United States)

    Cohort studies are fundamental for epidemiological research by helping researchers better understand the etiology of cancer and provide insights into the key determinants of this disease and its outcomes.

  5. Epidemiology & Genomics Research Program

    Science.gov (United States)

    The Epidemiology and Genomics Research Program, in the National Cancer Institute's Division of Cancer Control and Population Sciences, funds research in human populations to understand the determinants of cancer occurrence and outcomes.

  6. Sistema de vigilancia epidemiológica para el paciente diabético; el uso de tecnología computacional en la calidad de la atención médica Epidemiologic surveillance of diabetic patients; use of computer technology in the quality of medical care

    Directory of Open Access Journals (Sweden)

    Ramón Alberto Rascón-Pacheco

    2000-08-01

    Full Text Available OBJETIVO: Presentar un instrumento que permita llevar a cabo la vigilancia epidemiológica y evaluar la calidad de la atención a la diabetes mellitus en el primer nivel de atención. MATERIAL Y MÉTODOS: Este estudio se realizó del 1 de enero de 1998 al 30 de junio de 1999, en la Unidad de Investigación Epidemiológica y en Servicios de Salud, del Instituto Mexicano del Seguro Social (IMSS, en Hermosillo, Sonora. Se diseñó un formato único de reporte compuesto por los diferentes elementos que integran el sistema para la atención del paciente diabético en una Unidad de Medicina Familiar del IMSS. RESULTADOS: Se desarrolló e implementó un paquete de computación (software que permite la captura de los datos de dicho formato y la generación de reportes, de tipo individual y grupal, sobre el cumplimiento de citas, antecedentes personales patológicos y no patológicos, evolución de signos y síntomas, exámenes de laboratorio y el manejo terapéutico. CONCLUSIONES: La sistematización de datos en forma electrónica favorece la obtención de información confiable y permanente para la vigilancia de los procesos en la atención integral del paciente diabético.OBJECTIVE: To describe an instrument for epidemiologic surveillance of diabetes mellitus and evaluating the quality of care in primary health care. MATERIAL AND METHODS: The study was conducted from January 1, 1998, to June 30, 1999, at the Epidemiology and Health Services Research Unit of the Mexican Institute for Social Security (IMSS, in Hermosillo, Sonora. A single data collection form was designed, which contains items included in the diabetes care clinic of the Unit of Family Medicine of the Mexican Institute of Social Security. RESULTS: We developed and implemented a software program to enter data from the paper format and to generate individual and group reports on attendance to scheduled medical visits, medical history, evolution of signs and symptoms, laboratory tests, and

  7. Methodologic frontiers in environmental epidemiology.

    OpenAIRE

    Rothman, K J

    1993-01-01

    Environmental epidemiology comprises the epidemiologic study of those environmental factors that are outside the immediate control of the individual. Exposures of interest to environmental epidemiologists include air pollution, water pollution, occupational exposure to physical and chemical agents, as well as psychosocial elements of environmental concern. The main methodologic problem in environmental epidemiology is exposure assessment, a problem that extends through all of epidemiologic re...

  8. Condições de saneamento como indicador epidemiológico para Leishmaniose Tegumentar Americana na Amazônia sul ocidental brasileira | Sanitation conditions as an epidemiologic indicator for American Cutaneous Leishmaniasis in the Brazilian Southwestern Amazonia

    Directory of Open Access Journals (Sweden)

    Mateus Duarte Ribeiro

    2017-05-01

    Full Text Available Este estudo analisou as relações entre condições de saneamento e energia elétrica e a Leishmaniose Tegumentar Americana (LTA no estado do Acre. Utilizou-se os dados obtidos do Sistema de Informação de Agravos de Notificação entre 2001 e 2010 para correlacionar variáveis por meio da técnica de análise de componentes principais. O resultado indicou associação direta entre LTA e características inadequadas de moradia que podem ser agravantes à ocorrência dessa doença, como o abastecimento de água em rios ou lagos, o armazenamento de água da chuva, a destinação dos resíduos sólidos jogados em terrenos baldios e a falta de energia elétrica, estas em áreas rurais; em áreas rurais e urbanas, a ausência de banheiro ou esgotamento sanitário; e em áreas urbanas, em associação inversa, amenizando a ocorrência da LTA, o esgotamento sanitário utilizando fossa séptica. As associações encontradas sugerem que as condições inadequadas de saneamento contribuem para o aumento da exposição da população aos vetores da LTA. ================================================ This paper analyzes the relationship between sanitation and electricity service conditions, and American Cutaneous Leishmaniasis (ACL in Acre. For this study we considered the cases reported in the Brazilian System for Disease Notification between 2001 and 2010, using the principal component analysis. The analysis suggested a direct association between ACL and inadequate housing characteristics –that worsen the occurrence of this disease-, such as: water supply in river or lakes, rainwater storage, disposal of solid waste dumped in vacant lots, and absence of electricity service, in rural areas; and absence of bathrooms and sanitation, in both urban and rural areas. An inverse association arises, mitigating the occurrence of ACL, in urban areas, by using septic tanks for sewage. The associations found in this study suggest that inadequate housing

  9. La internalización del régimen internacional para el manejo de las relaciones laborales, por parte de las empresas transnacionales en los países periféricos. Estudio de caso: DHL Express (Ecuador) S.A.

    OpenAIRE

    Ronquillo Barzola, Gary Roberto

    2009-01-01

    Este trabajo explora las directrices globales como instrumentos, que proponen normas y principios en materia de empleo, formación, condiciones de trabajo y relaciones laborales por parte de las empresas transnacionales, propuestas en el marco de la Organización para la Cooperación y el Desarrollo Económico (OCDE) y la Organización Internacional del Trabajo (OIT), articulando como un régimen internacional del trabajo parcial, en construcción o inacabado, donde su eficacia varía ...

  10. Development of a technical scheme for the management of chemical dangerous substances in hospitable environments; Desarrollo de un esquema tecnico para la gestion de sustancias quimicas peligrosas en ambientes hospitalarios

    Energy Technology Data Exchange (ETDEWEB)

    Calleja Amador, C E

    2002-07-01

    The chemical substances that are used in the hospitals, and their remainders, represent risks for the environment, the health and security of those who work in these establishments, and of the civil population. The deficiency of a norm that establishes the directives for the handling responsible for such products in the hospitals that our country has motivated the elaboration of a technical scheme that serves as it guides for the correct manipulation, storage and safe disposition of chemical substances in the twenty-nine hospitals of the Caja Costarricense del Seguro Social, establishing Procedures of Standard Operation for its management. To development of the guideline proposal it took a sample of hospitals that includes three levels of comple complexity: national, regional and peripheral. Applying a methodology of evaluation of risks two factors of risk of hospitable were determined, the zones and the population but affected by the existence of chemical substances, which allowed to identify some operative deficiencies in the product handling diverse. The qualitative analysis of the results lead to the elaboration of a technical scheme that includes an instrument for the identification of risks, guideline for the management responsible for hospitable chemical substances, a friendly tool computations like complementary source of intelligence and the proposal of a governing group in charge of the monitoring of the fulfillment of these lineament. (Author) [Spanish] Las sustancias quimicas que se usan en los hospitales, y sus residuos, representan riesgos para el medio ambiente, para la salud y seguridad de quienes trabajan en estos establecimientos, y de la poblacion civil. La carencia de una normativa que establezca las directrices para el manejo responsable de tales productos en los hospitales de nuestro pais ha motivado la elaboracion de un esquema tecnico que sirva como guia para la correcta manipulacion, almacenamiento y disposicion segura de sustancias

  11. Análisis comparativo a las técnicas para modelar el funcionamiento de los sistemas de información

    Directory of Open Access Journals (Sweden)

    Gloria G. Madows

    2011-06-01

    Full Text Available En este trabajo se analizan las técnicas propuestas en los métodos actuales para especificar los aspectos de diálogo usuario-sistema de un producto software en el paradigma de desarrollo Orientado por Objetos. Esos métodos no ofrecen suficientes directrices acerca de cómo modelar dichos aspectos, y las técnicas disponibles necesitan algún refinamiento y elaboración para adaptar esa tarea en el proceso de especificación del software. Primero, se compara una serie de enfoques acerca de la temática; luego se describen los elementos comunes de los enfoques, y posteriormente se aplican a un conjunto de técnicas en el análisis de los requisitos funcionales.

  12. Nuevas relaciones laborales y salud de los trabajadores en Argentina: desafíos y perspectivas para la investigación New labor relations and workers' health in Argentina: challenges and perspectives for epidemiology

    Directory of Open Access Journals (Sweden)

    Jorge A. Kohen

    1997-01-01

    salaried, self-employed, and underemployed workers. The three National Meetings on Employment and Health (1992-1994 established an area of exchange between academic and workers' knowledge, with some 128 presentations, research projects, and studies, pointing to an enhanced field for epidemiological surveillance and intervention. The paper reviews the surveys performed by the National Confederation of Workers in Education and the Public Employees' Association.

  13. Análisis de costos de los métodos rápidos para diagnóstico de Tuberculosis multidrogorresistente en diferentes grupos epidemiológicos del Perú Cost analysis of rapid methods for diagnosis of multidrug resistant Tuberculosis in different epidemiologic groups in Perú

    Directory of Open Access Journals (Sweden)

    Lely Solari

    2011-09-01

    Full Text Available Objetivos. Evaluar los costos de tres métodos diagnósticos para susceptibilidad a drogas antituberculosas y comparar el costo por caso de tuberculosis multidrogorresistente (TB MDR diagnosticado con estos (MODS; GRIESS y Genotype MTBDR plus ® en cuatro grupos epidemiológicos en el Perú. Materiales y métodos. En base a cifras programáticas, se dividió a la población en cuatro grupos: pacientes nuevos de Lima/Callao; nuevos de otras provincias; los antes tratados de Lima/Callao y de otras provincias. Se calcularon los costos de cada prueba en base a la metodología estándar utilizada por el Ministerio de Salud, desde la perspectiva de los servicios de salud. Basado en ello, se calculó el costo por paciente TB MDR diagnosticado para cada grupo epidemiológico. Resultados. Los costos estimados por prueba para MODS, GRIESS, y Genotype MTBDR plus ® fueron de 14,83; 15,51 y 176,41 nuevos soles, respectivamente. El costo por paciente TB MDR diagnosticado con GRIESS y MODS fue menor a los 200 nuevos soles en tres de los cuatro grupos. El costo por TB MDR diagnosticado fue de más de 2000 nuevos soles con el Genotype MTBDR plus ® en los dos grupos de pacientes nuevos y, menores a 1000 nuevos soles en los grupos de pacientes antes tratados. Conclusiones. En grupos de alta prevalencia, como son los pacientes antes tratados, los costos por caso diagnosticado de TB MDR con las tres pruebas evaluadas fueron bajos, sin embargo, con la prueba molecular en los grupos de baja prevalencia, fueron elevados. El uso de las pruebas moleculares debe optimizarse en grupos de altas prevalencias.Objectives.To evaluate the costs of three methods for the diagnosis of drug susceptibility in tuberculosis, and to compare the cost per case of Multidrug-resistant tuberculosis (MDR TB diagnosed with these (MODS, GRIESS and Genotype MTBDR plus ® in 4 epidemiologic groups in Peru. Materials and methods.In the basis of programmatic figures, we divided the population in

  14. Against Popperized epidemiology.

    Science.gov (United States)

    Jacobsen, M

    1976-03-01

    The recommendation of Popper's philosophy of science should be adopted by epidemiologists is disputed. Reference is made to other authors who have shown that the most constructive elements in Popper's ideas have been advocated by earlier philosophers and have been used in epidemiology without abandoning inductive reasoning. It is argued that Popper's denigration of inductive methods is particularly harmful to epidemiology. Inductive reasoning and statistical inference play a key role in the science; it is suggested that unfamiliarity with these ideas contributes to widespread misunderstanding of the function of epidemiology. Attention is drawn to a common fallacy involving correlations between three random variables. The prevalence of the fallacy may be related to confusion between deductive and inductive logic.

  15. Ophthalmic epidemiology in Europe

    DEFF Research Database (Denmark)

    Delcourt, Cécile; Korobelnik, Jean-François; Buitendijk, Gabriëlle H S

    2016-01-01

    The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170,000 Euro......The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170......,000 European participants. The aim of the consortium is to promote and sustain collaboration and sharing of data and knowledge in the field of ophthalmic epidemiology in Europe, with particular focus on the harmonization of methods for future research, estimation and projection of frequency and impact...

  16. Nuclear accidents and epidemiology

    International Nuclear Information System (INIS)

    1987-01-01

    A consultation on epidemiology related to the Chernobyl accident was held in Copenhagen in May 1987 as a basis for concerted action. This was followed by a joint IAEA/WHO workshop in Vienna, which reviewed appropriate methodologies for possible long-term effects of radiation following nuclear accidents. The reports of these two meetings are included in this volume, and cover the subjects: 1) Epidemiology related to the Chernobyl nuclear accident. 2) Appropriate methodologies for studying possible long-term effects of radiation on individuals exposed in a nuclear accident. Figs and tabs

  17. Advances in radiation epidemiology

    International Nuclear Information System (INIS)

    Boice, J.

    1997-01-01

    The 1994 UNSCEAR report provides an informative review of radiation epidemiology. During the past 2 years there have been several major advances in our understanding of radiation effects based on new studies of atomic bomb survivors in Japan, of patients given diagnostic and therapeutic radiation (including iodine-131), of workers occupationally exposed, and of general populations exposed to residential radon. Laboratory approaches are also being incorporated into epidemiological investigations to learn more about the biological mechanism by which radiation causes cancer in man. (author)

  18. Epidemiologia das infecções por rotavírus no Brasil e os desafios para o seu controle Rotavirus infection in Brazil: epidemiology and challenges for control

    Directory of Open Access Journals (Sweden)

    Alexandre C. Linhares

    2000-09-01

    Full Text Available Os rotavírus causam de 600.000 a 870.000 óbitos por ano entre crianças em todo o mundo. Esses vírus foram visualizados pela primeira vez no Brasil em 1976, a partir da microscopia eletrônica das fezes de crianças diarréicas em Belém, Pará. Estudos conduzidos em hospitais registraram prevalência de diarréia por rotavírus de 12% e 42%. A par disso, investigações longitudinais assinalaram taxa média de 0,25 episódio de diarréia por criança/ano. Os tipos G1, G2, G3 e G4 representam cerca de 2/3 das amostras circulantes, porém, sustenta-se que o genótipo P[8], G5 associa-se a, no mínimo, 10% das diarréias. Estudos sobre a imunidade natural para rotavírus revelaram que 70% das crianças adquirem anticorpos já aos 4-5 anos de idade. A vacina tetravalente, de origem símio-humana (RRV-TV conferiu proteção de 35% após dois anos de estudo; contudo, o nível protetor alcançou 60% no primeiro ano de vida. A RRV-TV, no norte do Brasil, revelou eficácia de 75% frente às diarréias graves. Há poucos meses interrompeu-se o uso dessa vacina nos EUA devido à ocorrência de intussuscepção como efeito colateral. É provável que futuros experimentos no Brasil contemplem outras "candidatas" a vacina contra rotavírus, que não a RRV-TV.Worldwide, rotaviruses account for 600,000 to 870,000 deaths per year among infants and young children. In Brazil, rotaviruses were first seen in 1976 by scanning electron microscopy of stool samples from diarrheic infants in Belém, Pará. Hospital-based studies have shown that rotaviruses are associated with 12-42% of cases of acute diarrhea. In addition, community-based studies yielded an average of 0.25 rotavirus-related diarrheal episodes per child per year. G types 1 to 4 account for about two-thirds of circulating strains, but the (unusual P[8],G5 genotype has been claimed to cause over 10% of rotavirus diarrheal episodes. It has been shown that over 70% of children develop rotavirus antibodies

  19. Epidemiology of burns

    NARCIS (Netherlands)

    Dokter, Jan

    2016-01-01

    The aim of this thesis is to understand the epidemiology, treatment and outcomes of specialized burn care in The Netherlands. This thesis is mainly based on historical data of the burn centre in Rotterdam from 1986, combined with historical data from the burn centres in Groningen and Beverwijk from

  20. Translational Epidemiology in Psychiatry

    Science.gov (United States)

    Weissman, Myrna M.; Brown, Alan S.; Talati, Ardesheer

    2012-01-01

    Translational research generally refers to the application of knowledge generated by advances in basic sciences research translated into new approaches for diagnosis, prevention, and treatment of disease. This direction is called bench-to-bedside. Psychiatry has similarly emphasized the basic sciences as the starting point of translational research. This article introduces the term translational epidemiology for psychiatry research as a bidirectional concept in which the knowledge generated from the bedside or the population can also be translated to the benches of laboratory science. Epidemiologic studies are primarily observational but can generate representative samples, novel designs, and hypotheses that can be translated into more tractable experimental approaches in the clinical and basic sciences. This bedside-to-bench concept has not been explicated in psychiatry, although there are an increasing number of examples in the research literature. This article describes selected epidemiologic designs, providing examples and opportunities for translational research from community surveys and prospective, birth cohort, and family-based designs. Rapid developments in informatics, emphases on large sample collection for genetic and biomarker studies, and interest in personalized medicine—which requires information on relative and absolute risk factors—make this topic timely. The approach described has implications for providing fresh metaphors to communicate complex issues in interdisciplinary collaborations and for training in epidemiology and other sciences in psychiatry. PMID:21646577

  1. The Epidemiology of Pheochromocytoma

    DEFF Research Database (Denmark)

    Ladefoged Ebbehøj, Andreas

    2017-01-01

    Pheochromocytoma and catecholamine secreting paraganglioma (PPGL) are exceedingly rare endocrine tumours, but remain a frequent diagnostic dilemma due to their potential life-threatening nature. Reliable data on the epidemiology of PPGL is lacking and no time trends in incidence rates (IR) have...

  2. Intoxicação por agrotóxicos no Brasil: os sistemas oficiais de informação e desafios para realização de estudos epidemiológicos Pesticides poisoning in Brazil: the official notification system and challenges to conducting epidemiological studies

    Directory of Open Access Journals (Sweden)

    Neice Müller Xavier Faria

    2007-03-01

    Full Text Available O Brasil é um dos líderes mundiais em consumo de agrotóxicos e os trabalhadores expostos são numerosos e diversificados. As intoxicações agudas são a face mais visível do impacto destes produtos na saúde. A avaliação dos vários sistemas oficiais de informação que notificam os casos de intoxicações concluiu que nenhum deles responde adequadamente ao papel de sistema de vigilância. Na prática, só se registram os casos agudos e mais graves. Uma importante lacuna é a informação de exposição a agrotóxicos: a avaliação da única fonte oficial (os Receituários Agronômicos revelou muitas limitações. A revisão das publicações brasileiras aponta um crescimento quantitativo e qualitativo dos estudos nesta área, com vários tipos de abordagens. O impacto da intensa carga química e o enorme contingente de trabalhadores expostos são duas importantes razões para o desenvolvimento da pesquisa epidemiológica sobre intoxicações por agrotóxicos, que no Brasil ainda tem um vasto campo para se desenvolver.Brazil is one of the world leaders in pesticide consumption and exposed workers are numerous and diversified. Acute poisonings are just the most visible aspect of pesticide impact on human health. An assessment of many official information systems that notify pesticide poisoning concluded that none of them performed appropriately the role of a surveillance system. Only acute and severe cases are notified. One of the main gaps concerns exposure information: the only official source (the Agronomic Prescriptions has many limitations and is not available for research. A review of published articles in Brazil shows a quantitative and qualitative increase of studies in this area with many different approaches. The impact of such a high chemical burden and the huge numbers of workers exposed are two important reasons for the development of an epidemiological research on pesticide poisoning, an issue that has still a vast field to

  3. Endemic pemphigus in the peruvian Amazon: epidemiology and risk factors for the development of complications during treatment Pênfigo endêmico na Amazônia peruana: epidemiologia e fatores de risco para o desenvolvimento de complicações durante o tratamento

    Directory of Open Access Journals (Sweden)

    Willy Ramos

    2012-12-01

    Full Text Available BACKGROUND: Pemphigus is an autoimmune blistering disease. According to a report, in areas of endemic pemphigus foliaceus (EPF in Peru there are cases of pemphigus vulgaris with epidemiologic, clinical and histopathologic characteristics similar to those of "endemic pemphigus vulgaris" (EPV in Brazil. OBJECTIVES: To determine the clinical and epidemiologic characteristics of endemic pemphigus and the risk factors of patients for developing complications during treatment. METHODS: A study was carried out from July 2003 to March 2008. The study population was 60 patients with EPF and 7 patients with EPV evaluated in hospitals and clinics in the Peruvian Amazon and Lima. A multivariate analysis was carried out using binary logistic regression. RESULTS: The average age of EPF patients was 31.4 years; 55% were men; 60% presented the generalized clinical variant. Non-compliance with the treatment was seen in 57.1% of the patients. Thirty-five percent presented complications (e.g. pyodermitis and pyelonephritis during treatment. The risk factors for developing complications during treatment were non-compliance with the treatment and having the generalized clinical form. In the EPV group, the average age was 21.7 years; 71.4% were men. All patients presented with the mucocutaneous clinical variant and the initial presentation consisted of oral mucosa lesions; 71.4% presented complications during treatment, pyodermitis being the most frequent. CONCLUSIONS: Non-compliance with the treatment and the generalized clinical form are risk factors for the development of complications during treatment of patients with EPF. Peru indeed has EPV cases with epidemiologic characteristics similar to EPF. Living in a rural area may represent a risk factor for the development of complications during treatment of patients with EPV.FUNDAMENTOS: O pênfigo é uma doença auto-imune bolhosa. Segundo um relatório, em áreas de pênfigo foliáceo endêmico no Peru há casos

  4. Epidemiology applied to health physics

    International Nuclear Information System (INIS)

    1983-01-01

    The technical program of the mid-year meeting of the Health Physics Society, entitled Epidemiology Applied to Health physics, was developed to meet three objectives: (1) give health physicists a deeper understanding of the basics of epidemiological methods and their use in developing standards, regulations, and criteria and in risk assessment; (2) present current reports on recently completed or on-going epidemiology studies; and (3) encourage greater interaction between the health physics and epidemiology disciplines. Included are studies relating methods in epidemiology to radiation protection standards, risk assessment from exposure to bone-seekers, from occupational exposures in mines, mills and nuclear facilities, and from radioactivity in building materials

  5. Epidemiology and ionizing radiations

    International Nuclear Information System (INIS)

    Bourguignon, M.; Masse, R.; Slama, R.; Spira, A.; Timarche, M.; Laurier, D.; Billon, S.; Rogel, A.; Telle Lamberton, M.; Catelinois, O.; Thierry, I.; Grosche, B.; Ron, E.; Vathaire, F. de; Cherie Challine, L.; Donadieu, J.; Pirard, Ph.; Bloch, J.; Setbon, M.

    2004-01-01

    The ionizing radiations have effects on living being. The determinist effects appear since a threshold of absorbed dose of radiation is reached. In return, the stochastic effects of ionizing radiations are these ones whom apparition cannot be described except in terms of probabilities. They are in one hand, cancers and leukemia, on the other hand, lesions of the genome potentially transmissible to the descendants. That is why epidemiology, defined by specialists as the science that studies the frequency and distribution of illness in time and space, the contribution of factors that determine this frequency and this distribution among human populations. This issue gathers and synthesizes the knowledge and examines the difficulties of methodologies. It allows to give its true place to epidemiology. (N.C.)

  6. Epidemiology of Gout

    Science.gov (United States)

    Choi, Hyon

    2014-01-01

    Synopsis Gout is the most prevalent inflammatory arthritis in men. The findings of several epidemiological studies from a diverse range of countries suggest that the prevalence of gout has risen over the last few decades. Whilst incidence data are scarce, data from the US suggests that the incidence of gout is also rising. Evidence from prospective epidemiological studies has confirmed dietary factors (animal purines, alcohol and fructose), obesity, the metabolic syndrome, hypertension, diuretic use, and chronic kidney disease as clinically relevant risk factors for hyperuricemia and gout. Low-fat dairy products, coffee, and vitamin C appear to have a protective effect. Further prospective studies are required to examine other proposed risk factors for hyperuricaemia and gout such as the use of β-blockers and angiotension-II receptor antagonists (other than losartan), obstructive sleep apnoea, and osteoarthritis, and putative protective factors such as calcium-channel blockers and losartan. PMID:24703341

  7. Epidemiological studies on syncope

    DEFF Research Database (Denmark)

    Ruwald, Martin Huth

    2013-01-01

    of the patients play an essential role. In epidemiology these factors have major impact on the outcome of the patients. Until recently, even the definition of syncope differed from one study to another which has made literature reviews difficult. Traditionally the data on epidemiology of syncope has been taken...... from smaller studies from different clinical settings with wide differences in patient morbidity. Through the extensive Danish registries we examined the characteristics and prognosis of the patients hospitalized due to syncope in a nationwide study. The aims of the present thesis were to investigate......, prevalence and cardiovascular factors associated with the risk of syncope, 4) the prognosis in healthy individuals discharged after syncope, and 5) the prognosis of patients after syncope and evaluation of the CHADS2 score as a tool for short- and long-term risk prediction. The first studies of the present...

  8. The leukemias: Epidemiologic aspects

    International Nuclear Information System (INIS)

    Linet, M.S.

    1984-01-01

    Particularly geared to physicians and cancer researchers, this study of the epidemiology and etiology of leukemia analyzes the four major leukemia subtypes in terms of genetic and familial determinant factors and examines the incidence, distribution and frequency of reported leukemia clusters. Linet discusses the connection between other types of malignancies, their treatments, and the subsequent development of leukemia and evaluates the impact on leukemia onset of such environmental factors as radiation therapy, drugs, and occupational hazards

  9. Worldwide Report, Epidemiology

    Science.gov (United States)

    1985-11-22

    caused by ingesting eggs of the pork tapeworm, Taenia solium . It has been described as the most com- mon parasitic disease of the central nervous...rather difficult to detect in stool specimens and at this stage it is impossible to distinguish between T. solium and T. saginata eggs either by...Knowledge and Perspectives, pp. 25-38. Academic Press, New York. 12. Pawlowskz S. (1982). Epidemiology and prevention of Taenia saginata infec- tion. In

  10. Epidemiology and moral philosophy.

    OpenAIRE

    Westrin, C G; Nilstun, T; Smedby, B; Haglund, B

    1992-01-01

    To an increasing extent ethical controversies affect and sometimes obstruct public health work and epidemiological research. In order to improve communication between the concerned parties a model for identification and analysis of ethical conflicts in individual-based research has been worked out in co-operation between epidemiologists and moral philosophers. The model has two dimensions. One dimension specifies relevant ethical principles (as beneficence, non-maleficence, autonomy and justi...

  11. Perfil epidemiológico de nascimentos em Foz do Iguaçu/PR: indicador para planejamento do cuidado do enfermeiro Perfil epidemiológico de nacimientos en Foz do Iguaçu/PR: indicador para el cuidado de planificación del enfermero Epidemiologic profile of births in Foz do Iguaçu/PR: indicator for planning nursing care

    Directory of Open Access Journals (Sweden)

    Karen Simone Fizinus Rodrigues

    2010-09-01

    6,30% hasta 2,29% de las mujeres no realizaron prenatal y 29,01% a 56,94% de las mujeres no había completado la escuela primaria. Se concluye que el análisis realizado por la enfermera de la Declaración de Nacido Vivo es una excelente herramienta para planear las acciones que visan a la calidad de la atención a la mujer durante el embarazo, parto, puerperio y recién nacido.Study aimed at knowing the epidemiological profile of the newborns in the city of Foz do Iguaçu, Paraná, from 2000 to 2008, based on the Information of Live Birth Database, and on its main instrument, the Life Birth Certificate. It is a descriptive, retrospective research with a quantitative approach. In order to organize and apply the data, Excel® software was used. The variables included place of birth, sex, birth weight, gestational age, type of delivery, maternal age, education and number of prenatal care. Out of the total of 49.742 live births, 7.65 % to 9.01% were born with less than 2,500g; 5.42% to 7,37% were born premature; 19,21% to 24,55% were children of teenage mothers, which 5,58% to 7,13% were premature; 6,30% to 2,29% of the women did not have prenatal and 29,01% to 56,94% did not complete primary school. The conclusion was that the analysis made by the nurse from the Life Birth Certificate is an excellent tool to plan future actions that aim quality of care to the woman during pregnancy, delivery, postpartum and to the newborn.

  12. Bases epidemiológicas para análise das más oclusões morfológicas como fatores de risco no desenvolvimento das desordens temporomandibulares de origem articular Epidemiological basis for the analysis of morphologic malocclusion as a risk factor for the development of temporomandibular joint disorders

    Directory of Open Access Journals (Sweden)

    Ricardo de Souza Tesch

    2004-10-01

    Full Text Available Dentre as pesquisas empreendidas no campo da epidemiologia, um grupo específico aborda patologias de etiologia desconhecida ou não totalmente compreendidas. É dentro deste grupo que estão situadas as desordens temporomandibulares (DTM. Três estratégias observacionais básicas têm sido utilizadas para abordar o papel etiológico da má oclusão no desenvolvimento das DTM, dentro do repertório epidemiológico. São elas: estudos do tipo transversal, estudos de caso controle e estudos de coorte. Alguns experimentos clínicos são realizados com base na remoção do fator etiológico suspeito. Com base em uma revisão estruturada da literatura, a partir da metodologia empregada nos estudos selecionados, podemos concluir que a definição dos possíveis fatores etiológicos relacionados a subgrupos específicos de DTM é fundamental para que o papel das más oclusões no desenvolvimento destas desordens, embora pareça pequeno quando baseado nas evidências disponíveis, não seja subestimado. Pode ser útil a caracterização de uma oclusão normal como aquela associada como o menor risco para o desenvolvimento de problemas de DTM, mas é provavelmente inapropriada a aplicação destes parâmetros para reverter um problema intra-capsular já estabelecido. O conceito de uma oclusão de baixo fator de risco implicaria em um pequeno desvio entre RC e MIH, pequeno transpasse horizontal, transpasse vertical positivo e ausência de mordida cruzada posterior. Este conceito é compatível com o conceito de oclusão normal defendido por décadas, embora uma variação do normal ao invés de um critério absoluto deva ser permitida. Embora provavelmente seja prudente estabelecer metas morfológicas terapêuticas que busquem o que é observado em oclusões não tratadas julgadas normais ou ideais, o estabelecimento de uma oclusão que alcance todos os critérios gnatológicos, por meio de tratamento ortodôntico, talvez seja impossível e provavelmente

  13. Propuesta didáctica para el trabajo de la relajación en el área de Educación Física

    OpenAIRE

    Martín López, Sara

    2014-01-01

    Este trabajo refleja la importancia de la relajación como contenido de aprendizaje en el área de Educación Física. También, se presenta una propuesta de intervención educativa para desarrollar la relajación en esta área. Dicha propuesta se fundamenta en la búsqueda de información, análisis y reflexiones de los autores más relevantes, sobre los métodos, técnicas y directrices generales a tener en cuenta a la hora de poner en práctica el trabajo de la relajación. Grado en Educación Primaria...

  14. Concurso para viviendas en la manzana limitada por las calles Raimundo Fernández Villaverde, Alonso Cano, Maudes y Ponzano, Madrid-España

    Directory of Open Access Journals (Sweden)

    Coderch y de Sentmenat, J. A.

    1978-06-01

    Full Text Available The guideline ideas of the project for this competition have been: on the level of the detailed study - the adaptation to a residential use of the block which had been foreseen as for the construction of office buildings, on the basis of unifying the garden areas, adjusting and broadening the accesses and pedestrian crossings and striving for architectural aesthetics more in consonance with the new use; and, on the level of the dwelling - having all of the bedrooms and main living areas look on to the outside, with ventilation by interior patios solely for kitchens and stairways.

    Las ideas directrices del proyecto para este concurso han sido: a nivel del estudio de detalle, la reordenación de volúmenes, a base de unificar las zonas ajardinadas y adecuar y ampliar los accesos y pasos peatonales; y, a nivel de vivienda, conseguir que todos los dormitorios y dependencias principales.

  15. 24 mars 2016 - Le Président de la Confédération suisse, Monsieur Johann Schneider-Ammann signe le livre d'or avec la Directrice générale du CERN Fabiola Gianotti.

    CERN Multimedia

    Brice, Maximilien

    2016-01-01

    Le Président de la Confédération suisse, Monsieur Johann Schneider-Ammann signe le livre d'or avec la Directrice générale du CERN Fabiola Gianotti. De g. à d.: F. Eder, Délégué aux Relations avec les Etats-hôtes; F. Bordry, Directeur des accélérateurs et de la technologie; S. E. M. l'Ambassadeur Fasel, Représentant permanent de la Suisse auprès de l’Office des Nations Unies et des autres organisations internationales à Genève; M. Steinacher, Directeur des finances et des ressources humaines et P. Pardo, Conseiller, Mission permanente de la Suisse auprès de l’Office des Nations Unies et des autres organisations internationales à Genève.

  16. Evaluación de conformidad en la calibración del canal de medición de conductividad para aguas farmacéuticas

    Directory of Open Access Journals (Sweden)

    Adolfo Castillo Caballero

    2017-12-01

    Full Text Available Entre los sistemas críticos para la producción de productos inyectables en el Centro de Inmunología Molecular se encuentra el canal de medición de la conductividad, tanto para agua purificada como para el agua para inyección. De acuerdo con el cumplimiento de las Buenas Prácticas de Producción, estos sistemas se someten regularmente a procesos de validación, donde la calibración del canal de conductividad es una práctica obligatoria para la calificación del desempeño. Un equipo o sistema de medición para ser fiable requiere una evaluación de la conformidad, con una probabilidad mayor o igual al 95%. Para dar cumplimiento a los requisitos regulatorios y directrices actuales se propone como criterio la evaluación de la conformidad en la calibración del sistema de agua farmacéutica. Se armoniza el procedimiento de calibración y las regulaciones farmacéuticas internacionales actuales para la medición de la conductividad del agua para productos inyectables. Se definieron las características metrológicas, las fuentes de incertidumbre se cuantifican y se determinan los intervalos de aceptación, para conseguir una probabilidad de la conformidad en la calibración igual al 95% a partir del conocimiento de la capacidad de medición, con el fin de responder a los requerimientos de las agencias regulatorias internacionales para la industria biofarmacéutica.

  17. Worldwide epidemiology of fibromyalgia.

    Science.gov (United States)

    Queiroz, Luiz Paulo

    2013-08-01

    Studying the epidemiology of fibromyalgia (FM) is very important to understand the impact of this disorder on persons, families and society. The recent modified 2010 classification criteria of the American College of Rheumatology (ACR), without the need of tender points palpation, allows that larger and nationwide surveys may be done, worldwide. This article reviews the prevalence and incidence studies done in the general population, in several countries/continents, the prevalence of FM in special groups/settings, the association of FM with some sociodemographic characteristics of the population, and the comorbidity of FM with others disorders, especially with headaches.

  18. Epidemiology of Posttraumatic Osteoarthritis.

    Science.gov (United States)

    Thomas, Abbey C; Hubbard-Turner, Tricia; Wikstrom, Erik A; Palmieri-Smith, Riann M

    2017-06-02

    Osteoarthritis is a leading cause of disability whose prevalence and incidence continue to increase. History of joint injury represents an important risk factor for posttraumatic osteoarthritis and is a significant contributor to the rapidly growing percentage of the population with osteoarthritis. This review will present the epidemiology associated with posttraumatic osteoarthritis, with particular emphasis on the knee and ankle joints. It is important to understand the effect of posttraumatic osteoarthritis on the population so that sufficient resources can be devoted to countering the disease and promoting optimal long-term health for patients after joint injury.

  19. Molecular epidemiology of ascariasis

    DEFF Research Database (Denmark)

    Betson, Martha; Halstead, Fennella; Nejsum, Peter

      We are using molecular epidemiology techniques to study the population structure of Ascaris obtained from humans and pigs. Worms were obtained from human hosts on Zanzibar and in Uganda, Bangladesh, Guatemala and Nepal and Ascaris from pigs were collected from in Uganda, Tanzania, Denmark......, Guatemala and the Philippines. Genomic DNA was extracted from each worm and a 450 base pair fragment of the mitochondrial cytochrome oxidase gene subunit 1 (COI) was PCR amplified. The products were sequenced from both strands and sequences were manually edited. Fifty different Ascaris CO1 haplotypes were...

  20. Sistema de vigilância epidemiológica para acidentes do trabalho: experiência na Zona Norte do Município de São Paulo (Brasil Epidemiological vigilance system for accidents at work: first results from an experience in the Northern zone of S. Paulo City (Brazil

    Directory of Open Access Journals (Sweden)

    Ubiratan de Paula Santos

    1990-08-01

    Full Text Available No Brasil, e em São Paulo em particular, o sistema de vigilância epidemiológica restringe-se a algumas doenças transmissíveis, não havendo, na prática, vigilância referente a doenças não transmissíveis, especialmente às decorrentes do trabalho. O atual sistema de informações para acidentes e doenças do trabalho tem sido utilizado mais para o processamento de benefícios aos acidentados e acometidos por doenças do trabalho, do que para a proposta de um sistema de vigilância. Assim, foi elaborado projeto visando a utilizar os instrumentos em uso nesse sistema de notificação, para extrair informações que possam, dentro de uma abordagem epidemiológica, dar suporte ao planejamento das atividades de saúde. O projeto encontra-se em andamento no Programa de Saúde dos Trabalhadores do SUDS-R-6 (Mandaqui, Região da Grande São Paulo (Brasil, e objetiva identificar os tipos de acidentes mais comuns na região e os ambientes de trabalho nos quais esses acidentes ocorrem com mais freqüência. Os primeiros dados analisados, correspondentes ao período de outubro a novembro de 1989, mostraram uma média de 780 acidentes mensais. As mãos e os dedos foram as partes do corpo mais atingidas, cerca de 31,5% de todos os acidentes estudados, particularmente causados por máquinas e equipamentos na indústria metalúrgica. Dos acidentes registrados, 371 (15,86% foram considerados graves, com uma alta incidência de contusões e traumas com fraturas. Das CAT estudadas, 2.030 (87% foram decorrentes de acidentes típicos e 298 (12,7% de trajeto. Aproximadamente 7%, 165 casos, ocorreram em trabalhadores menores de 18 anos de idade e 10 casos tinham idade inferior a 14 anos de idade. A identificação das companhias dos ramos da construção civil, metalúrgica e indústria gráfica como aquelas que apresentam o maior número de acidentes, definiu os primeiros critérios para o planejamento das atividades do Programa de Saúde dos Trabalhadores

  1. Worldwide Report, Epidemiology, No. 327

    National Research Council Canada - National Science Library

    1983-01-01

    Partial Contents: Epidemiology, Human Diseases, Health, Malaria, AIDS, Homosexual Male, Medical Administration, Rabies, Tuberculosis, Encephalitis Statistics, Gastroenteritie, Mystery Diseases, Children, Epidemics...

  2. Epidemiology, hunger and development

    Directory of Open Access Journals (Sweden)

    Paulo H. Battaglin Machado

    2008-06-01

    Full Text Available Understanding the relationship between epidemiology and food security implies in disclosing famine causes, the way it is distributed in the society and to which extent it affects the populations. Building up from that perspective, this paper attempts to understand the famine logic throughout the various transitions accomplished in the past decades: epidemiologic, demographic, risk, nutritional and development. The reflexes of the demographic transition that took place in Brazil in the XXth century are related to the population nutritional status standard changes, that is, they shifted from malnutrition high prevalence to a significant increase in obesity. However, the paradox of this situation is due to the fact that most risk factors that bring about diseases of the modern world come from the “excess”, while millions die around the globe because of “deprivation”. The food production alone does not ensure its equitable distribution among the various groups of the society. The access alone does not lead to quality. The choices are made individually, but life style options imply in a set of correlations that go from economy to culture. It means that this field has a collective basis and encompasses environment and development.

  3. Global epidemiology of sporotrichosis.

    Science.gov (United States)

    Chakrabarti, Arunaloke; Bonifaz, Alexandro; Gutierrez-Galhardo, Maria Clara; Mochizuki, Takashi; Li, Shanshan

    2015-01-01

    Sporotrichosis is an endemic mycosis caused by the dimorphic fungus Sporothrix schenckii sensu lato. It has gained importance in recent years due to its worldwide prevalence, recognition of multiple cryptic species within the originally described species, and its distinctive ecology, distribution, and epidemiology across the globe. In this review, we describe the current knowledge of the taxonomy, ecology, prevalence, molecular epidemiology, and outbreaks due to S. schenckii sensu lato. Despite its omnipresence in the environment, this fungus has remarkably diverse modes of infection and distribution patterns across the world. We have delved into the nuances of how sporotrichosis is intimately linked to different forms of human activities, habitats, lifestyles, and environmental and zoonotic interactions. The purpose of this review is to stimulate discussion about the peculiarities of this unique fungal pathogen and increase the awareness of clinicians and microbiologists, especially in regions of high endemicity, to its emergence and evolving presentations and to kindle further research into understanding the unorthodox mechanisms by which this fungus afflicts different human populations. © The Author 2014. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  4. Clinical Epidemiology Of Stroke

    Directory of Open Access Journals (Sweden)

    Nagaraja D

    2005-01-01

    Full Text Available Stroke is a huge public health problem because of its high morbidity and disability. The epidemiology of stroke is of relevance to construct practical paradigms to tackle this major health issue in the community. Recent data have shown that about 72-86% of strokes are ischemic, 9-18% are due to hemorrhage (intracerebral of subarachnoid and the rest are undefined. The risk factors for stroke are multiple and combined. At present, stroke is no more considered as unavoidable and untreatable. It is an emergency and specialized units and teams improve outcome and lower costs. Death related to stroke is declining in many countries and in both sexes. This decrease in multifactorial. The detection and more effective treatment of hypertension may play an important factor, as well as the improved medical care and improvement in diagnostic procedures. While stroke incidence appears stable and stroke mortality is slowly declining, the absolute magnitude of stroke is likely to grow over the next 30 years. as the population ages, the absolute number of stroke victims and demands on healthcare and other support systems is likely to increase substantially in the future. Keeping this in perspective, this chapter shall focus on the epidemiology of stroke in the world and in Indian, in particular.

  5. EMPREGO DO RELAXAMENTO PARA ALÍVIO DA DOR EM ONCOLOGIA

    Directory of Open Access Journals (Sweden)

    MICHELE SALVADOR

    2008-01-01

    Full Text Available La finalidad de este estudio fue describir el uso de técnicas de relajación y sus beneficios para reducción del dolor oncológico. Se trata de una revisión de literatura, de 1993 a 2007, usando las palabras claves: dolor, relajación, cáncer y enfermería, en las bases Medline, Cinahl y Lilacs. De los 79 artículos identificados, 24 de ellos atendieron los propósitos. De estos, sólo uno era nacional; predominantemente de autores enfermeros, publicados en revistas norteamericanas de enfermería y distribuidos hasta el año 2000; dos de ellos eran relatos de experiencia, uno de directrices, un estudio de caso, 10 revisiones de literatura y 10 ensayos. Los autores emplearon las técnicas de relajación muscular progresiva, imagen guiada, biofeedback, hipnosis y meditación. Tales técnicas reducen la percepción del dolor oncológico, favorecen la disminución de narcóticos, náuseas, estrés, insomnio y actúan como auxiliar con los medicamentos; la enfermera ocupa papel relevante en su uso para aliviar el dolor.

  6. Atividades educativas para o controle de triatomíneos em área de vigilância epidemiológica do Estado do Paraná, Brasil Health education for triatomine control in an area under epidemiological surveillance in Paraná State, Brazil

    Directory of Open Access Journals (Sweden)

    Ana Lucia Falavigna-Guilherme

    2002-12-01

    Full Text Available O objetivo deste artigo é descrever um projeto de atividades de educação sanitária para a comunidade rural e profissionais de saúde de municípios em fase de vigilância epidemiológica de triatomíneos no Paraná. Uma equipe composta de técnicos da Fundação Nacional de Saúde, professores, funcionários e acadêmicos da Universidade Estadual de Maringá foi treinada, preparando um manual de orientações e elaborando um fluxo a ser seguido em caso de denúncia de triatomíneo ou de indivíduo com suspeita de infecção pelo Trypanosoma cruzi. De junho de 1996 a fevereiro de 2000, as atividades incluíram 742 famílias, 2.300 alunos e 27 professores em 18 escolas de ensino fundamental, incluindo um evento para especialistas com 40 participantes, 21 reuniões em Postos de Saúde e a entrega de um mostruário com triatomíneos. Três anos após a realização dessas atividades e aspersão de inseticida (cipermetrina 125mg i.a./m², verificou-se redução de 80,6% das unidades domiciliares infestadas por triatomíneos, além da conscientização da comunidade rural e profissionais de saúde. Foi discutida a necessidade de formação de profissionais compromissados com a inversão do modelo de saúde vigente no País.This paper describes a health education project targeting a rural community and health professionals from counties undergoing epidemiological surveillance for Chagas disease vectors in the State of Paraná, Brazil. A group of technicians from the Brazilian National Health Foundation (FUNASA was trained, together with teachers, workers, and students from the State University of Maringá, who prepared an instructions manual and drew up guidelines for reporting presence of triatomines or suspected cases of Trypanosoma cruziinfection. From June 1996 through February 2000, the activities reached 742 families, 2,300 schoolchildren, and 27 teachers from 18 elementary schools, and included a meeting between FUNASA members and 40

  7. Cancer Epidemiology Data Repository (CEDR)

    Science.gov (United States)

    In an effort to broaden access and facilitate efficient data sharing, the Epidemiology and Genomics Research Program (EGRP) has created the Cancer Epidemiology Data Repository (CEDR), a centralized, controlled-access database, where Investigators can deposit individual-level de-identified observational cancer datasets.

  8. CEDR: Comprehensive Epidemiologic Data Resource

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    The Department of Energy (DOE) and its predecessor agencies have a long history of epidemiologic research programs. The main focus of these programs has been the Health and Mortality Study of the DOE work force. This epidemiologic study began in 1964 with a feasibility study of workers at the Hanford facility. Studies of other populations exposed to radiation have also been supported, including the classic epidemiologic study of radium dial painters and studies of atomic bomb survivors. From a scientific perspective, these epidemiologic research program have been productive, highly credible, and formed the bases for many radiological protection standards. Recently, there has been concern that, although research results were available, the data on which these results were based were not easily obtained by interested investigators outside DOE. Therefore, as part of an effort to integrate and broaden access to its epidemiologic information, the DOE has developed the Comprehensive Epidemiologic Data Resource (CEDR) Program. Included in this effort is the development of a computer information system for accessing the collection of CEDR data and its related descriptive information. The epidemiologic data currently available through the CEDAR Program consist of analytic data sets, working data sets, and their associated documentation files. In general, data sets are the result of epidemiologic studies that have been conducted on various groups of workers at different DOE facilities during the past 30 years.

  9. Epidemiology of fibromyalgia.

    Science.gov (United States)

    Neumann, Lily; Buskila, Dan

    2003-10-01

    Chronic widespread pain, the cardinal symptom of fibromyalgia (FM), is common in the general population, with comparable prevalence rates of 7.3% to 12.9% across different countries. The prevalence of FM in the general population was reported to range from 0.5% to 5% and up to 15.7% in the clinic. The common association of FM with other rheumatic disorders, chronic viral infections, and systemic illnesses has been well documented in several studies. Up to 65% of patients with systemic lupus erythematosus meet the criteria for FM. FM is considered a member of the family of functional somatic syndromes. These syndromes are very common and share a similar phenomenology, epidemiologic characteristics, high rates of occurrence, a common pathogenesis, and similar management strategies. A high prevalence of FM was demonstrated among relatives of patients with FM and it may be attributed to genetic and environmental factors.

  10. [Epidemiology of osteoporosis].

    Science.gov (United States)

    Grazio, Simeon

    2006-01-01

    Osteoporosis represents a major and increasing public health problem with the aging of population. Major clinical consequences and economic burden of the disease are fractures. Many risk factors are associated with the fractures including low bone mass, hormonal disorders, personal and family history of fractures, low body weight, use of certain drugs (e.g. glucocorticoids), cigarette smoking, elevated intake of alchohol, low physical activity, insufficient level of vitamin D and low intake of calcium. This epidemiological review describes frequency, importance of risk factors and impact of osteoporosis and osteoporotic fractures. Objective measures of bone mineral density along with clinical assessment of risk factors can help identify patients who will benefit from prevention and intervention efforts and eventually reduce the morbidity and mortality associated with osteoporosis-related fractures.

  11. Temporal network epidemiology

    CERN Document Server

    Holme, Petter

    2017-01-01

    This book covers recent developments in epidemic process models and related data on temporally varying networks. It is widely recognized that contact networks are indispensable for describing, understanding, and intervening to stop the spread of infectious diseases in human and animal populations; “network epidemiology” is an umbrella term to describe this research field. More recently, contact networks have been recognized as being highly dynamic. This observation, also supported by an increasing amount of new data, has led to research on temporal networks, a rapidly growing area. Changes in network structure are often informed by epidemic (or other) dynamics, in which case they are referred to as adaptive networks. This volume gathers contributions by prominent authors working in temporal and adaptive network epidemiology, a field essential to understanding infectious diseases in real society.

  12. [Ethics and epidemiology].

    Science.gov (United States)

    Barata, Rita Barradas

    2005-01-01

    Human actions take place at the confluence of circumstances that require us to discern the proper way to act. Ethics falls within the terrain of practical knowledge, of knowledge about what is contingent. It belongs to the domain of moral judgments or value judgments. The counterpart of disenchantment with our contemporary world lies in an effort to re-establish an interest in ethics. There are basically three orders of relations between public health and human rights: the quest for balance between the collective good and individual rights; methods and techniques for identifying human rights violations and assessing their negative impact; and the tie between protecting individual rights and promoting health. The relationship between ethics and epidemiology goes beyond the ethical aspects involving research on human beings to encompass political commitments, practices within health services, and the production of knowledge.

  13. The Epidemiology of Sarcoma

    Directory of Open Access Journals (Sweden)

    Burningham Zachary

    2012-10-01

    Full Text Available Abstract Sarcomas account for over 20% of all pediatric solid malignant cancers and less than 1% of all adult solid malignant cancers. The vast majority of diagnosed sarcomas will be soft tissue sarcomas, while malignant bone tumors make up just over 10% of sarcomas. The risks for sarcoma are not well-understood. We evaluated the existing literature on the epidemiology and etiology of sarcoma. Risks for sarcoma development can be divided into environmental exposures, genetic susceptibility, and an interaction between the two. HIV-positive individuals are at an increased risk for Kaposi’s sarcoma, even though HHV8 is the causative virus. Radiation exposure from radiotherapy has been strongly associated with secondary sarcoma development in certain cancer patients. In fact, the risk of malignant bone tumors increases as the cumulative dose of radiation to the bone increases (p for trend

  14. Epidemiology of Lyme Disease

    Directory of Open Access Journals (Sweden)

    Dennis J White

    1991-01-01

    Full Text Available Investigation of the epidemiology of Lyme disease depends upon information generated from several sources. Human disease surveillance can be conducted by both passive and active means involving physicians, public health agencies and laboratories. Passive and active tick surveillance programs can document the extent of tick-borne activity, identify the geographic range of potential vector species, and determine the relative risk of exposure to Lyme disease in specific areas. Standardized laboratory services can play an important role in providing data. Epidemiologists can gain a better understanding of Lyme disease through the collection of data from such programs. The interpretation of data and provision of information to the medical and general communities are important functions of public health agencies.

  15. Participatory epidemiology: the contribution of participatory research to epidemiology

    Directory of Open Access Journals (Sweden)

    Mario Bach

    2017-02-01

    Full Text Available Abstract Background Epidemiology has contributed in many ways to identifying various risk factors for disease and to promoting population health. However, there is a continuing debate about the ability of epidemiology not only to describe, but also to provide results which can be better translated into public health practice. It has been proposed that participatory research approaches be applied to epidemiology as a way to bridge this gap between description and action. A systematic account of what constitutes participatory epidemiology practice has, however, been lacking. Methods A scoping review was carried out focused on the question of what constitutes participatory approaches to epidemiology for the purpose of demonstrating their potential for advancing epidemiologic research. Relevant databases were searched, including both the published and non-published (grey literature. The 102 identified sources were analyzed in terms of comparing common epidemiologic approaches to participatory counterparts regarding central aspects of the research process. Exemplary studies applying participatory approaches were examined more closely. Results A highly diverse, interdisciplinary body of literature was synthesized, resulting in a framework comprised of seven aspects of the research process: research goal, research question, population, context, data synthesis, research management, and dissemination of findings. The framework specifies how participatory approaches not only differ from, but also how they can enhance common approaches in epidemiology. Finally, recommendations for the further development of participatory approaches are given. These include: enhancing data collection, data analysis, and data validation; advancing capacity building for research at the local level; and developing data synthesis. Conclusion The proposed framework provides a basis for systematically developing the emergent science of participatory epidemiology.

  16. Propuesta orientativa para la recuperación de los alumnos de primer año de enseñanza media (15 años de edad, que presentan problemas de aprendizaje en Matemáticas en Brasil. Atención e importancia de necesidades socio-educativas

    Directory of Open Access Journals (Sweden)

    Ana María Ribeiro

    2010-03-01

    Full Text Available Los objetivos del estudio son identificar, en el contexto de la problemática de la repetición escolar, los factores de bajo rendimiento y, a partir de esto, establecer directrices y estrategias para programas de orientación correctiva y para la formación de profesores en matemáticas de la 1ª serie del 2º grado, en Santa Catarina, Brasil. Los datos teóricos fueron buscados en la literatura pedagógica e interdicisplinar, nacional e internacional, y los empíricos vinieron de la investigación de campo en puestos de trabajo, administración pública, currículo oficial, empresas, comercio y, principalmente, de las escuelas (alumnos repetidores, profesores de matemáticas y especialistas en educación a través de cuestionarios.

  17. Educación ambiental para la sustentabilidad en la educación secundaria

    Directory of Open Access Journals (Sweden)

    Calixto Flores, Raúl

    2015-09-01

    Full Text Available En este ensayo se analizan los programas de estudio del nivel medio básico de México en el campo de formación, exploración y comprensión del mundo natural y social, relacionado con la educación ambiental para la sustentabilidad y las implicaciones que se pueden derivar para la docencia (estos programas tienen un carácter nacional. En los programas de estudio analizados se encuentran elementos de la sustentabilidad débil, fuerte y súper fuerte. Estas categorías son propuestas por el especialista Eduardo Gudynas para diferenciar las distintas nociones de la sustentabilidad. En los resultados del análisis se observa el predominio de la sustentabilidad débil en los programas de estudio. La sustentabilidad débil se asocia más con las directrices del desarrollo sustentable que con las propuestas de la educación ambiental, por cuanto esta última propone aprovechar los recursos no sólo económicos sino también naturales con la intención de producir lo que la sociedad demanda. Esta visión ambiental, resalta la idea de cuidar los ecosistemas mediante la administración eficiente de los recursos. Como aporte del análisis realizado a los programas de estudio del nivel medio básico se destaca la importancia de incluir temas sociales y culturales en la docencia de la educación ambiental para la sustentabilidad. Esta perspectiva en la educación ambiental contribuye a la formación de una actitud crítica hacia los problemas ambientales, develando contradicciones sociales y construyendo alternativas comprometidas con el bien común.

  18. The epidemiology of endometriosis.

    Science.gov (United States)

    Cramer, Daniel W; Missmer, Stacey A

    2002-03-01

    Advances in understanding the epidemiology of endometriosis have lagged behind other diseases because of methodologic problems related to disease definition and control selection. Nevertheless, a better picture of the epidemiology of endometriosis has emerged over the past few decades. Prevalence estimates of the disease in clinic populations vary from about a 4% occurrence of largely asymptomatic endometriosis found in women undergoing tubal ligation to 50% of teenagers with intractable dysmenorrhea. General population incidence during the 1970s in this country has been suggested to be 1.6 per 1000 white females aged 15-49, while a more current study based upon hospital discharges finds endometriosis as a first listed diagnosis in 1.3 per 1000 discharges in women aged 15-44. There is a clinical impression that blacks have lower rates of endometriosis and Orientals have higher rates than whites. A variety of personal risk factors for endometriosis have also been described. Women with endometriosis may be taller and thinner. Menstrual factors reported to increase risk include dysmenorrhea, early menarche, and shorter cycle lengths. There is support for the idea that lifestyle exposures that might raise or lower estrogen levels could affect risk, including a decreased risk associated with smoking and exercise and an increased risk associated with caffeine or alcohol use. These risk factors appear to be compatible with the central importance of retrograde menstruation influenced by outflow obstruction that might affect its amount, immune factors that might affect its ability to be cleared, or hormonal stimuli that might affect its growth. In this model, dysmenorrhea could be either a disease symptom or a manifestation of outflow obstruction. Nulliparity could be either a consequence of disease or a cause since nulliparous women would not have the benefit of cervical dilation associated with labor and delivery. Since there is evidence that family history is a risk

  19. La capacidad de gobernanza de la UE para dar respuesta a la crisis económica y evaluar y prevenir las necesidades futuras del mercado de trabajo

    Directory of Open Access Journals (Sweden)

    Francisco González-Blanch

    2011-05-01

    Full Text Available La gobernanza económica es una prioridad en las políticas comunitarias especialmente hoy, ante una crisis que confiere una imprevisibilidad excepcional en el porvenir de la economía europea. El examen de las causas de la crisis ha destacado diversas debilidades del Modelo Social Europeo. Los instrumentos de gobernanza del MSE (directivas, Directrices Integradas, método abierto de coordinación, Diálogo social, aprendizaje mutuo, programas comunitarios deben revisarse para que sean pertinentes en la situación actual. La capacidad de la UE y los EEMM para prever, anticipar y adaptar las competencias requeridas a las necesidades del mercado de trabajo constituye una condición esencial para la elaboración de políticas de empleo eficaces. La evaluación puede aportar criterios e instrumentos útiles para desarrollar la capacidad de gobernanza de la política de empleo con el fin de hacer frente a las necesidades actuales del mercado de trabajo y posibles reformas.

  20. Epidemiology of prostatitis

    Science.gov (United States)

    Krieger, John N.; Lee, Shaun Wen Huey; Jeon, Jeonseong; Cheah, Phaik Yeong; Liong, Men Long; Riley, Donald E.

    2008-01-01

    Background Prostatitis describes a combination of infectious diseases (acute and chronic bacterial prostatitis), chronic pelvic pain syndrome, and asymptomatic inflammation. Materials and methods We employed evidence-based methods to review the epidemiology of prostatitis syndromes. Results The prevalence of prostatitis symptoms could be compared in five studies surveying 10 617 men. Overall, 873 participants met various criteria for prostatitis, representing an overall rate of 8.2%, with prevalence ranging from 2.2 to 9.7%. A history of sexually transmitted diseases was associated with an increased risk for prostatitis symptoms. Men reporting a history of prostatitis symptoms had a substantially increased rate of benign prostatic hyperplasia, lower urinary tract symptoms and prostate cancer. In one study, the incidence of physician-diagnosed prostatitis was 4.9 cases per 1000 person-years. Two studies suggest that about one-third of men reporting prostatitis symptoms had resolution after 1 year. Patients with previous episodes and more severe symptoms are at higher risk for chronic pelvic pain. Discussion The prevalence of prostatitis symptoms is high, comparable to rates of ischamic heart disease and diabetes. Clinical evaluation appears necessary to verify that prostatitis is responsible for patients’ symptoms. Prostatitis symptoms may increase a man’s risk for benign prostate hypertrophy, lower urinary tract symptoms and prostate cancer. We need to define natural history and consequences of prostatitis, develop better algorithms for diagnosis and treatment, and develop strategies for prevention. PMID:18164907

  1. Epidemiology of Lung Cancer

    Science.gov (United States)

    Brock, Malcolm V.; Ford, Jean G.; Samet, Jonathan M.; Spivack, Simon D.

    2013-01-01

    Background: Ever since a lung cancer epidemic emerged in the mid-1900s, the epidemiology of lung cancer has been intensively investigated to characterize its causes and patterns of occurrence. This report summarizes the key findings of this research. Methods: A detailed literature search provided the basis for a narrative review, identifying and summarizing key reports on population patterns and factors that affect lung cancer risk. Results: Established environmental risk factors for lung cancer include smoking cigarettes and other tobacco products and exposure to secondhand tobacco smoke, occupational lung carcinogens, radiation, and indoor and outdoor air pollution. Cigarette smoking is the predominant cause of lung cancer and the leading worldwide cause of cancer death. Smoking prevalence in developing nations has increased, starting new lung cancer epidemics in these nations. A positive family history and acquired lung disease are examples of host factors that are clinically useful risk indicators. Risk prediction models based on lung cancer risk factors have been developed, but further refinement is needed to provide clinically useful risk stratification. Promising biomarkers of lung cancer risk and early detection have been identified, but none are ready for broad clinical application. Conclusions: Almost all lung cancer deaths are caused by cigarette smoking, underscoring the need for ongoing efforts at tobacco control throughout the world. Further research is needed into the reasons underlying lung cancer disparities, the causes of lung cancer in never smokers, the potential role of HIV in lung carcinogenesis, and the development of biomarkers. PMID:23649439

  2. TUBERCULOSIS: EPIDEMIOLOGY AND CONTROL

    Directory of Open Access Journals (Sweden)

    Giorgia Sulis

    2014-10-01

    Full Text Available Tuberculosis (TB is a major public health concern worldwide: despite a regular, although slow, decline in incidence over the last decade, as many as 8.6 million new cases and 1.3 million deaths were estimated to have occurred in 2012. TB is by all means a poverty-related disease, mainly affecting the most vulnerable populations in the poorest countries. The presence of multidrug-resistant strains of M. tuberculosis in most countries, with some where prevalence is high, is among the major challenges for TB control, which may hinder recent achievements especially in some settings. Early TB case detection especially in resource-constrained settings and in marginalized groups remains a challenge, and about 3 million people are estimated to remain undiagnosed or not notified and untreated. The World Health Organization (WHO has recently launched the new global TB strategy for the “post-2015 era” aimed at “ending the global TB epidemic” by 2035, based on the three pillars that emphasize patient-centred TB care and prevention, bold policies and supportive systems, and intensified research and innovation. This paper aims to provide an overview of the global TB epidemiology as well as of the main challenges that must be faced to eliminate the disease as a public health problem everywhere.

  3. Epidemiology of severe trauma.

    Science.gov (United States)

    Alberdi, F; García, I; Atutxa, L; Zabarte, M

    2014-12-01

    Major injury is the sixth leading cause of death worldwide. Among those under 35 years of age, it is the leading cause of death and disability. Traffic accidents alone are the main cause, fundamentally in low- and middle-income countries. Patients over 65 years of age are an increasingly affected group. For similar levels of injury, these patients have twice the mortality rate of young individuals, due to the existence of important comorbidities and associated treatments, and are more likely to die of medical complications late during hospital admission. No worldwide, standardized definitions exist for documenting, reporting and comparing data on severely injured trauma patients. The most common trauma scores are the Abbreviated Injury Scale (AIS), the Injury Severity Score (ISS) and the Trauma and Injury severity Score (TRISS). Documenting the burden of injury also requires evaluation of the impact of post-trauma impairments, disabilities and handicaps. Trauma epidemiology helps define health service and research priorities, contributes to identify disadvantaged groups, and also facilitates the elaboration of comparable measures for outcome predictions. Copyright © 2014 Elsevier España, S.L.U. y SEMICYUC. All rights reserved.

  4. Radiobiology and Epidemiology

    International Nuclear Information System (INIS)

    Desaintes, C; Holmstock, L.

    2001-01-01

    The main objectives of research in the field of radiobiology and epidemiology performed at the Belgian Nuclear Research Centre SCK-CEN are: (1) to study cancer mortality in nuclear workers in Belgium and to co-ordinate the Belgian contribution to the 'International Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry'; (2) to elucidate the molecular basis of individual susceptibility to ionizing radiation in mammalian embryo during the early phases of its development; (3) to assess the genetic risk of maternal exposure to ionizing radiation; (4) to elucidate the cellular mechanisms leading to brain damage after prenatal irradiation; (5) to monitor the early variations of gene expression induced by ionising radiation and cytokines; (6) to evaluate the use of cytokines and natural substances for improving radiotherapy protocols; (6) to advise authorities and to provide the general population with adequate information concerning the health risk arising from radiation exposure. Progress and major achievements in these topical areas in 2000 are reported

  5. Radiobiology and Epidemiology

    Energy Technology Data Exchange (ETDEWEB)

    Desaintes, C; Holmstock, L

    2001-04-01

    The main objectives of research in the field of radiobiology and epidemiology performed at the Belgian Nuclear Research Centre SCK-CEN are: (1) to study cancer mortality in nuclear workers in Belgium and to co-ordinate the Belgian contribution to the 'International Collaborative Study of Cancer Risk among Radiation Workers in the Nuclear Industry'; (2) to elucidate the molecular basis of individual susceptibility to ionizing radiation in mammalian embryo during the early phases of its development; (3) to assess the genetic risk of maternal exposure to ionizing radiation; (4) to elucidate the cellular mechanisms leading to brain damage after prenatal irradiation; (5) to monitor the early variations of gene expression induced by ionising radiation and cytokines; (6) to evaluate the use of cytokines and natural substances for improving radiotherapy protocols; (6) to advise authorities and to provide the general population with adequate information concerning the health risk arising from radiation exposure. Progress and major achievements in these topical areas in 2000 are reported.

  6. Indoor radon epidemiological study

    Energy Technology Data Exchange (ETDEWEB)

    Kunz, E; Tomasek, L; Mueller, T [National Radiation Protection Institute, Prague (Czech Republic); Placek, V [Inst. for Expertises and Emergencies, Pribram-Kamenna (Czech Republic); Matzner, J; Heribanova, A [State Office for Nuclear Safety, Prague (Czech Republic)

    1996-12-31

    The study is a long-term prospective cohort study of lung cancer and possibility other causes of death. The study population includes inhabitants of the area, who had resided there for at three years and at least one of these between 1.1.1960 and 21.12.1989. A total of 11865 inhabitants satisfied these criteria. The cumulative exposure of each respondent is being assessed on the basis of measurements in dwellings, time spent there and estimation of previous exposure levels by a model accounting for constructional changes in buildings. One year lasting measurements of radon daughter products by integral dosimeters (Kodak film LR 115) were performed in practically all dwellings of the specified area. Radon measurements in houses in term of equilibrium concentration are compared with the results of a pilot study in Petrovice in 1990-91 which gave the stimulus for the epidemiological study. The distribution of death causes and ratio of observed (O) to expected (E) cases among collected death cases in the cohort, generally, somewhat lower ratios than one reflect the non-industrial character of the region, with the exception of lung cancer in man. The differences in the O/E ratios for lung cancer among the separate communities indicate that even in the situation of generally lower mortality, the dependence of lung cancer mortality on radon.

  7. Diretrizes brasileiras de hipertensão arterial: realidade da enfermagem em hospital especializado Directrices brasileras de hipertensión arterial: realidad de la enfermería en un hospital especializado Brazilian guidelines for arterial hypertension: the reality of nursing in a specialty hospital

    Directory of Open Access Journals (Sweden)

    Liliana Fortini Cavalheiro Boll

    2012-01-01

    Full Text Available OBJETIVO: Avaliar o conhecimento sobre a técnica da verificação da pressão arterial nos profissionais de enfermagem em uma instituição de saúde. Identificar a relação entre a qualificação profissional e o desenvolvimento correto da técnica. MÉTODOS: O pesquisador aplicou um questionário aos profissionais de enfermagem durante a verificação da pressão arterial dos pacientes, questões estas relativas às V Diretrizes Brasileiras de Hipertensão Arterial. RESULTADOS: Dos profissionais de enfermagem, técnicos e auxiliares, 8,41 %, atingiram o ponto de corte estipulado como adequado de acertos (80%. Houve relação direta entre a qualificação profissional e a quantidade de acertos. CONCLUSÃO: As V Diretrizes Brasileiras de Hipertensão Arterial não são seguidas em sua plenitude pelos profissionais de enfermagem. A ampla divulgação das diretrizes, a implementação de programas de capacitação e a monitoração da técnica devem ser incentivadas.OBJETIVO: Evaluar el conocimiento sobre la técnica de la verificación de la presión arterial en los profesionales de enfermería en una institución de salud. Identificar la relación entre la calificación profesional y el desarrollo correcto de la técnica. MÉTODOS: El investigador aplicó un cuestionario a los profesionales de enfermería durante la verificación de la presión arterial de los pacientes, preguntas que fueron relativas a las V Directrices Brasileras de Hipertensión Arterial. RESULTADOS: De los profesionales de enfermería, técnicos y auxiliares, el 8,41 %, alcanzaron el punto de corte estipulado como adecuado de aciertos (80%. Hubo relación directa entre la calificación profesional y la cantidad de aciertos. CONCLUSIÓN: Las V Directrices Brasileras de Hipertensión Arterial no son seguidas en su plenitud por los profesionales de enfermería. La amplia difusión de las directrices, la implementación de programas de capacitación y el monitoramiento de la t

  8. Investigación sobre morteros y sus tratamientos para su restauración en el Retablo del Altar Mayor de la Basílica del Pilar

    OpenAIRE

    Luxán, M. P.; Dorrego, F.; Sotolongo, R.

    2000-01-01

    El retablo de la Asunción de María está situado en el Altar Mayor de la Basílica del Pilar en Zaragoza y es una de las grandes obras del Patrimonio artístico español. La obra, esculpida en alabastro, fue realizada entre 1509 y ¡518 por Damián Forment. En este trabajo se recogen las directrices para el diseño de los morteros de reparación utilizados en la restauración del retablo. Se basaron en criterios de compatibilidad de los materiales y tratamientos existentes en el retablo, según la i...

  9. Metabolomics and Epidemiology Working Group

    Science.gov (United States)

    The Metabolomics and Epidemiology (MetEpi) Working Group promotes metabolomics analyses in population-based studies, as well as advancement in the field of metabolomics for broader biomedical and public health research.

  10. Genomic Resources for Cancer Epidemiology

    Science.gov (United States)

    This page provides links to research resources, complied by the Epidemiology and Genomics Research Program, that may be of interest to genetic epidemiologists conducting cancer research, but is not exhaustive.

  11. Occupational reproductive epidemiology: Pt. 1

    International Nuclear Information System (INIS)

    Roman, Eve; Doyle, Pat

    1993-01-01

    The authors review the current state of knowledge about possible adverse effects of hazardous paternal workplace exposures on human reproduction is scant. The methodology for studying possible association between occupational exposures and adverse reproductive events is not well developed. More detailed laboratory and epidemiological research is clearly required, and better collaboration between these two disciplines is needed. Associations suggested in the course of epidemiological research need to be tested in the laboratory, and vice versa. (author)

  12. para palmito

    Directory of Open Access Journals (Sweden)

    Francisco Paulo Chaimsohn

    2007-01-01

    Full Text Available Densidades de siembra, arreglos espaciales y fertilización en pejibaye (Bactris gasipaes cv Diamantes-10 para palmito. La investigación se llevó a cabo en la Estación Experimental Los Diamantes (Guápiles, Costa Rica, el 3 de octubre del 2003, cuyo objetivo fue la evaluación del efecto de diferentes densidades de siembra (3.333, 5.000 y 6.666 plantas/ha, arreglos espaciales, y diversos métodos de fertilización (química, orgánica, sobre el crecimiento de las plantas de pejibaye para producción de palmito. Se consideraron las variables diámetro y altura del tallo primario y el número de hojas y rebrotes como indicadores de producción. El período de evolución abarcó sólo los primeros 25 meses de crecimiento en el campo. El número de hojas, la altura y el diámetro del tallo no mostraron diferencias de respuesta relevantes. Sólo el número de rebrotes disminuyó al aumentar la densidad de la población, cuando se midió a los 15 meses de edad. El efecto de la fertilización se hizo evidente después de la primera cosecha, realizada a los 20 meses, debido al aumento de la competencia entre plantas, ahora más desarrolladas. Fue entonces cuando la fertilización química indujo la producción de un mayor número y vigor de los rebrotes. Sin embargo, las prácticas evaluadas 25 meses después de la siembra, no habían infl uido hasta ese momento en el número de palmitos cosechados, ni tampoco había afectado las características físicas de los sectores foliar y caulinar del palmito.

  13. Directrices para la gestión de residuos sólidos em ambientes de alta montaña : estudio de caso em la Cordillera de Huayhuash - Perú = Diretrizes para a gestão de resíduos sólidos em ambientes de alta montanha: estudo de caso na Cordilheira de Huayhuash - Peru

    OpenAIRE

    Omar Milton Romero Catacora

    2013-01-01

    Resumo: Este estudo teve como objetivo analisar questões relacionadas à gestão e gerenciamento de resíduos sólidos em regiões montanhosas, desde sua geração impulsionada pelo aumento desenfreado do turismo nessas regiões, até sua disposição final. Esse processo desenfreado do turismo está deixando um enorme impacto ambiental nas geleiras e nas cabeceiras de bacias hidrográficas que são regiões de abastecimento de água localizadas ao pé das montanhas. Foi realizada uma análise de padrões mais ...

  14. Una caza del tesoro para aprender la pronunciación del español

    Directory of Open Access Journals (Sweden)

    Xose Padilla García

    2012-08-01

    Full Text Available El grupo Pronuncia bien surgió en el seno del Máster de Enseñanza de español einglés como L2/LE de la Universidad de Alicante bajo la dirección del profesor Xose A.Padilla. El objetivo de nuestro grupo es elaborar instrumentos de aprendizaje quepermitan mejorar la pronunciación de estudiantes de E/LE de manera eficaz y divertida.A día de hoy, el grupo ha creado materiales didácticos dirigidos especialmente aestudiantes cuya lengua de origen sea el inglés o el italiano. La creación de lasherramientas didácticas y de evaluación propiamente dichas se basa en los principios delMétodo Verbo-Tonal (MVT, en las propuestas del enfoque comunicativo, y en el usode las nuevas tecnologías (TICs. Tenemos en cuenta, asimismo, las directrices delMarco Común Europeo de Referencia para las lenguas (MCER y los consejos del PlanCurricular del Instituto Cervantes (PCIC sobre la enseñanza del español.

  15. Una caza del tesoro para aprender la pronunciación del español

    Directory of Open Access Journals (Sweden)

    Xose Padilla García

    2009-01-01

    Full Text Available El grupo Pronuncia bien surgió en el seno del Máster de Enseñanza de español e inglés como L2/LE de la Universidad de Alicante bajo la dirección del profesor Xose A.Padilla. El objetivo de nuestro grupo es elaborar instrumentos de aprendizaje que permitan mejorar la pronunciación de estudiantes de E/LE de manera eficaz y divertida.A día de hoy, el grupo ha creado materiales didácticos dirigidos especialmente a estudiantes cuya lengua de origen sea el inglés o el italiano. La creación de las herramientas didácticas y de evaluación propiamente dichas se basa en los principios del Método Verbo-Tonal (MVT, en las propuestas del enfoque comunicativo, y en el uso de las nuevas tecnologías (TICs. Tenemos en cuenta, asimismo, las directrices del Marco Común Europeo de Referencia para las lenguas (MCER y los consejos del Plan Curricular del Instituto Cervantes (PCIC sobre la enseñanza del español.

  16. La Terapia Dialéctico Conductual para el tratamiento del Trastorno Límite de la Personalidad.

    Directory of Open Access Journals (Sweden)

    Matilde Elices

    2011-06-01

    Full Text Available La Terapia Dialéctico Conductual (TDC ha sido creada por la Dra. Marsha Linehan, para el tratamiento de pacientes con intentos suicidas recurrentes y diagnóstico de Trastorno Limite de la Personalidad (TLP. Es un modelo terapéutico perteneciente a la “tercera ola” en psicoterapias cognitivas, puesto que se basa en las ciencias del comportamiento e incluye elementos de Mindfulness y de la filosofía dialéctica. En la actualidad la TDC es el tratamiento con mayor evidencia empírica para el TLP, demostrando ser efectiva en la reducción de varios problemas asociados a este trastorno, como ser: autolesiones, intentos de autoeliminación, ideación suicida, desesperanza, depresión y comportamientos asociados a la bulimia. El objetivo de este artículo es desarrollar los fundamentos teóricos y conceptuales básicos sobre los que se construye la TDC, y exponer sus principales directrices de tratamiento. También se establecen las principales diferencias con la terapia cognitivo – conductual standard.

  17. Una metodología activa para la resolución de problemas

    Directory of Open Access Journals (Sweden)

    Miró-Julià, Margaret

    2006-01-01

    Full Text Available El objetivo de esta ponencia es presentar las conclusiones del proyecto de mejora de la calidad docente titulado “El uso de estrategias adecuadas para la resolución de problemas de Estadística” que se realizó en la Universidad de las Islas Baleares durante el curso 2005-2006. Debido a nuestra dilatada experiencia en la enseñanza de las asignaturas Estadística Económica y Métodos Matemáticos para la Economía I, II y III de los estudios que dependen de la Facultad de Economía, somos conscientes del desánimo y desinterés de nuestros alumnos. Es indiscutible que existen dificultades por parte de los profesores a la hora de enseñar, pero también existen obstáculos por parte de los alumnos para aprender. Esta problemática resulta evidente a la hora de resolver problemas. El proyecto, cuyas conclusiones presentamos, pretende ensayar nuevas formas de enseñanza/aprendizaje que responden a las recientes directrices del espacio Europeo. El proyecto está dirigido a potenciar la tarea del alumno a la hora de enfrentarse con un problema. Se basa fundamentalmente en la creación de guiones que ofrezcan al alumno las pautas a seguir a la hora de resolver problemas y que también le permitan realizar una auto-evaluación de los resultados obtenidos.

  18. INDICADORES DE SOSTENIBILIDAD PARA ÁREAS DE SEGUIMIENTO DEL PROYECTO DE RECUPERACIÓN

    Directory of Open Access Journals (Sweden)

    Thaiane Soares Montandon

    2015-07-01

    Full Text Available En los últimos años el crecimiento de la población y la acción del hombre se volvieron muchos ecosistemas, incrementando significativamente la cantidad de áreas degradadas. En vista de la necesidad de recuperar estas áreas, el gobierno brasileño determina la realización de zonas de recuperación de Proyectos Degradadas (Prads, incluyendo el monitoreo y evaluación de la zona. Este artículo se basa en dos formas de monitoreo, la SER propuesto (2004, que cuenta con directrices de recuperación universales, 9 atributos de las áreas restauradas y 3 estrategias de evaluación, aunque tiene indicadores no RAD ;. Y la propuesta MELO et al. (2010, que presenta un Proyecto Matriz de Evaluación de la Restauración, con 7 indicadores RAD. Los indicadores de sostenibilidad para estas áreas se definieron a través del Método Delphi. La aplicación de la matriz de indicadores de sostenibilidad es una herramienta importante para la planificación, seguimiento y evaluación de las áreas degradadas y el uso del método Delphi para construir la matriz asegura un trabajo de monitoreo y evaluación más eficiente y completa. DOI: http://dx.doi.org/10.12957/sustinere.2015.17326

  19. La gestión del conocimiento en las Bibliotecas Universitarias: ¿el qué, cómo y para qué?

    Directory of Open Access Journals (Sweden)

    Gerardo Sánchez Ambriz

    2013-04-01

    Full Text Available El presente artículo tiene como propósito proponer la incorporación de la teoría administrativa denominada Gestión del Conocimiento (GC, en Bibliotecas Universitarias (BU. ¿El qué, el cómo y el para qué? Representa un reto de gestión que conlleva a la implementación de diversas estrategias para el cambio y la innovación (ECI. Hipotéticamente, el diseño de estrategias de gestión posibilita que la BU en los escenarios competitivos de la sociedad de conocimiento y el tercer entorno desarrolle nuevas competencias y directrices para el aprovechamiento de sus diversos recursos con eficiencia y logren alcanzar sus objetivos con eficacia. La innovación es otra de las variables que posibilita la transformación de los servicios que son ofertados a los usuarios, también denominados “socios estratégicos”, bajo la visión de creatividad, sustentabilidad y bienestar

  20. Consideraciones teóricas para el análisis de la política industrial aplicada a la PYMI en América Latina

    Directory of Open Access Journals (Sweden)

    Mary A. Vera Colina

    2003-01-01

    Full Text Available El objetivo del documento consiste en analizar diferentes enfoques teóricos y empíricos recientes sobre la política industrial aplicada a las PYMIs en los países latinoamericanos, para lo cual se utilizó la metodología de la investigación documental de bibliografía especializada. Se presentan una serie de argumentos a favor de la intervención estatal en la promoción del desarrollo industrial y de las PYMIs, se describen propuestas para el diseño de la política industrial y se relatan algunas experiencias recientes en Latinoamérica. Los resultados del estudio indican que las nuevas propuestas van más allá del proteccionismo y se orientan a la coordinación de esfuerzos de los sectores público y privado, a promover los esquemas asociativos, el desarrollo tecnológico, la inserción en mercados internacionales y mejorar el acceso a financiamiento; los países analizados disponen de legislación que incluye los aspectos mencionados, pero aún no ejecutan completamente las políticas en ella establecidas, ni disponen de directrices integrales para el área de la innovación tecnológica.

  1. Epidemiology of idiopathic pulmonary fibrosis

    Directory of Open Access Journals (Sweden)

    Ley B

    2013-11-01

    Full Text Available Brett Ley, Harold R Collard Department of Medicine, Division of Pulmonary and Critical Care Medicine, University of California San Francisco, San Francisco, California, USA Abstract: Idiopathic pulmonary fibrosis is a chronic fibrotic lung disease of unknown cause that occurs in adults and has a poor prognosis. Its epidemiology has been difficult to study because of its rarity and evolution in diagnostic and coding practices. Though uncommon, it is likely underappreciated both in terms of its occurrence (ie, incidence, prevalence and public health impact (ie, health care costs and resource utilization. Incidence and mortality appear to be on the rise, and prevalence is expected to increase with the aging population. Potential risk factors include occupational and environmental exposures, tobacco smoking, gastroesophageal reflux, and genetic factors. An accurate understanding of its epidemiology is important, especially as novel therapies are emerging. Keywords: idiopathic pulmonary fibrosis, epidemiology, incidence, prevalence, mortality, risk factors

  2. Los huertos escolares comunitarios: fraguando espacios socioeducativos en y para la sostenibilidad

    Directory of Open Access Journals (Sweden)

    Ángela Barrón Ruiz

    2015-07-01

    Full Text Available Presentamos un proyecto educativo centrado en la conformación de una Red de huertos escolares ecológicos comunitarios, cuya finalidad es mostrar cómo tales huertos no sólo constituyen recursos educativos, sino que pueden convertirse en elementos vertebradores de cambio e innovación en la cultura escolar, permitiendo educar de un modo más integral y significativo, a la vez que capacitar a los educandos en las competencias transversales demandadas por la educación para el desarrollo sostenible. Para llevarlo a cabo se aplica una metodología de investigación-acción participativa (IAP, basada en el diálogo y la negociación como vías para que los participantes reflexionen y den solución conjunta a las diferentes necesidades y problemas que el proyecto va planteando. Los profesores universitarios, directores del proyecto, aplican con sus alumnos universitarios una metodología de Aprendizaje Servicio, poniendo en marcha, en colaboración con las diferentes instituciones participantes, un proyecto piloto inicial y una posterior red de huertos escolares comunitarios, siguiendo las directrices para la introducción de la sostenibilidad en el curriculum (CADEP-CRUE, 2005. La conclusión fundamental es que los huertos escolares, así concebidos, al integrar a la Comunidad, pueden llegar a constituir espacios socioeducativos transversales de gran valor educativo y social, dado que no sólo sirven para mejorar la intervención educativa, sino también para promover una cultura social comprometida con la sostenibilidadCómo referenciar este artículoBarrón Ruiz, Á., & Muñoz Rodríguez, J. M. (2015. Los huertos escolares comunitarios: fraguando espacios socioeducativos en y para la sostenibilidad. Foro de Educación, 13(19, 213-239. doi: http://dx.doi.org/10.14516/fde.2015.013.019.010

  3. Molecular epidemiology of human rhinoviruses

    OpenAIRE

    Savolainen-Kopra, Carita

    2006-01-01

    The first part of this work investigates the molecular epidemiology of a human enterovirus (HEV), echovirus 30 (E-30). This project is part of a series of studies performed in our research team analyzing the molecular epidemiology of HEV-B viruses. A total of 129 virus strains had been isolated in different parts of Europe. The sequence analysis was performed in three different genomic regions: 420 nucleotides (nt) in the VP4/VP2 capsid protein coding region, the entire VP1 capsid protein cod...

  4. Estrategias y herramientas pedagógicas para cualificación del Equipo de Salud de la Familia

    Directory of Open Access Journals (Sweden)

    Ivana Cristina H.C. BARRETO et al

    2007-04-01

    Full Text Available Construir efectivamente un sistema único público de salud universal, integral y igualitario, de acordo con lo que fue definido en la Constituyente para el Sistema Único de Salud de Brasil (SUS, exige de los gestores y trabajadores grandes esfuerzos en la área de la organización de los servicios y de la formación profesional. El Ministerio de la Salud de Brasil, en 2003, instiuyó la Política Nacional de Educación Permanente en Salud, como estrategia para formación y desarrollo de trabajadores para el sector, creando, desde entonces, innumeros proyectos con el objectivo de, a través del proceso educativo de los trabajadores en salud, posibilitaren la reorientación del modelo asistencial en salud. La efectividad de todos estes proyectos y programas exige, no obstante, que sea revista la estructura de formación en la área de la salud de uma manera más profunda y abrangente. La propuesta de creación de Sistemas de Salud Escuela estan en este contexto. La idea fuerza de un Sistema de Salud Escuela (SSE és crear una Estrategia de Educación Permanente en conjunto con las intituciones de enseñanza, organizaciones no guiernamentales y movimientos populares, transformando toda la red de servicios de salud existente en un determinado teritorio político-administrativo en espacios de educación contextualizada y de desarrollo profesional. Este artículo discute también la dimensión pedagógica y las directrices de um Sistema de Salud Escuela, bien como las implicaciones de ordenación en la formación de recursos humanos para el SUS.

  5. Epidemiological methods: a brief review

    International Nuclear Information System (INIS)

    Winkelstein, W. Jr.

    1983-01-01

    Epidemiology, the study of disease distributions in populations and the factors which influence these distributions, is an observational science, i.e., its data base consists of measurements made on free living individuals characterized by presence or absence of disease states and putative risk factors. Epidemiological studies are usually classified as descriptive or analytical. Descriptive studies are primarily used for planning and evaluating health programs or to generate etiological hypotheses. Analytical studies are primarily used for testing etiological hypotheses. Analytical studies are designed either as cohort investigations in which populations with and without a putative risk factor are followed through time to ascertain their differential incidence of disease, or case-control investigations in which the history of exposure to a putative risk factor is compared among persons with a disease and appropriate controls free of disease. Both descriptive and analytical epidemiological studies have been applied to health physics problems. Examples of such problems and the epidemiological methods used to explore them will be presented

  6. Glossary for econometrics and epidemiology.

    Science.gov (United States)

    Gunasekara, F Imlach; Carter, K; Blakely, T

    2008-10-01

    Epidemiologists and econometricians are often interested in similar topics-socioeconomic position and health outcomes-but the different languages that epidemiologists and economists use to interpret and discuss their results can create a barrier to mutual communication. This glossary defines key terms used in econometrics and epidemiology to assist in bridging this gap.

  7. Killing fields; The epidemiological evidence

    Energy Technology Data Exchange (ETDEWEB)

    Best, Simon

    1990-02-01

    The threat posed by low frequency fields emerged initially because a researcher, looking for environmental factors in childhood leukaemia, observed a link between low voltage, high current power lines and disease occurrence. Cellular evidence now supports the findings but epidemiology still leads the argument. (43 references). (author).

  8. Brain Tumor Epidemiology Consortium (BTEC)

    Science.gov (United States)

    The Brain Tumor Epidemiology Consortium is an open scientific forum organized to foster the development of multi-center, international and inter-disciplinary collaborations that will lead to a better understanding of the etiology, outcomes, and prevention of brain tumors.

  9. Candida infections : detection and epidemiology

    NARCIS (Netherlands)

    Borst, A. (Annemarie)

    2002-01-01

    Despite the fact that the yeast Candida is the number 4 cause of bloodstream infections in the United States and ranks number 8 in Europe, adequate detection methods are lacking. Furthermore, relatively little is known about the epidemiology of Candida. Our aim was to improve the detection and

  10. Panel 1 : Epidemiology and Diagnosis

    NARCIS (Netherlands)

    Homøe, Preben; Kværner, Kari; Casey, Janet R; Damoiseaux, Roger A M J; van Dongen, Thijs M A; Gunasekera, Hasantha; Jensen, Ramon G; Kvestad, Ellen; Morris, Peter S; Weinreich, Heather M

    Objective To create a literature review between 2011 and June 1, 2015, on advances in otitis media (OM) epidemiology and diagnosis (including relevant audiology studies). Data Sources Electronic search engines (PubMed, EMBASE, and Cochrane Library) with a predefined search strategy. Review Methods

  11. [Epidemiology of rabies in Algeria].

    Science.gov (United States)

    Benelmouffok, A; Belkaid, M; Benhassine, M

    An epidemiological study on rabies in Algeria has been carried out on data provided by the "Institut national de Santé publique" and the "Institut Pasteur d'Algérie". It showed that no region is unhurt. The animal reservoir is of the domestic type, essentially the dog. In 40% of cases, bites are due to stray dogs.

  12. TFOS DEWS II Epidemiology Report

    NARCIS (Netherlands)

    Stapleton, Fiona; Alves, Monica; Bunya, Vatinee Y.; Jalbert, Isabelle; Lekhanont, Kaevalin; Malet, Florence; Na, Kyung-Sun; Schaumberg, Debra; Uchino, Miki; Vehof, Jelle; Viso, Eloy; Vitale, Susan; Jones, Lyndon

    The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta-analysis of published prevalence data estimated the impact of age and sex. Global mapping of prevalence was

  13. Radiation epidemiology: Past and present

    International Nuclear Information System (INIS)

    Boice, J.D. Jr.

    1997-01-01

    Major advancements in radiation epidemiology have occurred during the last several years in studies of atomic bomb survivors, patients given medical radiation, and radiation workers, including underground miners. Risks associated with the Chernobyl accident, indoor radon and childhood exposure to I-131 have yet to be elucidated. Situations in the former Soviet Union around Chelyabinsk, a nuclear installation in the southern Urals, and in the Altai, which received radioactive fallout from weapons testing at Semipalatinsk, Kazakhstan, have the potential to provide information on the effects of chronic radiation exposure. Since Roentgen's discovery of x-rays just 100 years ago, a tremendous amount of knowledge has been accumulated about human health effects following irradiation. The 1994 UNSCEAR report contains the latest compilation and synthesis of radiation epidemiology. This overview will cover epidemiology from a radiation perspective. The different types of study methodologies will be described, followed by a kaleidoscope coverage of past and present studies; ending with some remaining questions in radiation epidemiology. This should set the stage for future chapters, and stimulate thinking about implications of the new data on radiation cancer risks

  14. [Occupational epidemiology: some methodological considerations].

    Science.gov (United States)

    Alvear-Galindo, María Guadalupe; del Pilar Paz-Román, María

    2006-01-01

    During the last decade, occupational epidemiology has gained a great importance, not only because of the increase of pollutants and their noxiousness, but also because it has gone from the descriptive to the analytic level. The purpose of this work is to present what has been reported on epidemiological studies, different ways of characterizing and measuring occupational exposure, by emphasizing slants of exposure and selection measurement. In the reviewed studies, an interest in improving the exposure evaluation has been shown. The mainly reported measurement slants are the ways of measuring and classifying the exposure. The main designs were transversal with the use of matrixes to improve the evaluation of exposure. Conditions of hygiene and security were considered in order to control the quality of the information. This information was analyzed with different criteria. Some of the elements that hinder the research on occupational epidemiology are a mixed exposure, small populations, lack of exposure data, low levels of exposure and long periods of illness latency. Some breakthroughs in the strategies of epidemiological analysis and some other areas of knowledge have made possible a better understanding of work and health conditions of workers.

  15. Development and application of Human Genome Epidemiology

    Science.gov (United States)

    Xu, Jingwen

    2017-12-01

    Epidemiology is a science that studies distribution of diseases and health in population and its influencing factors, it also studies how to prevent and cure disease and promote health strategies and measures. Epidemiology has developed rapidly in recent years and it is an intercross subject with various other disciplines to form a series of branch disciplines such as Genetic epidemiology, molecular epidemiology, drug epidemiology and tumor epidemiology. With the implementation and completion of Human Genome Project (HGP), Human Genome Epidemiology (HuGE) has emerged at this historic moment. In this review, the development of Human Genome Epidemiology, research content, the construction and structure of relevant network, research standards, as well as the existing results and problems are briefly outlined.

  16. About the Epidemiology and Genomics Research Program

    Science.gov (United States)

    Epidemiology is the scientific study of the causes and distribution of disease in populations. NCI-funded epidemiology research is conducted through research at institutions in the United States and internationally.

  17. Mitochondrial DNA and Cancer Epidemiology Workshop

    Science.gov (United States)

    A workshop to review the state-of-the science in the mitochondrial DNA field and its use in cancer epidemiology, and to develop a concept for a research initiative on mitochondrial DNA and cancer epidemiology.

  18. The evolving epidemiology of inflammatory bowel disease.

    LENUS (Irish Health Repository)

    Shanahan, Fergus

    2009-07-01

    Epidemiologic studies in inflammatory bowel disease (IBD) include assessments of disease burden and evolving patterns of disease presentation. Although it is hoped that sound epidemiologic studies provide aetiological clues, traditional risk factor-based epidemiology has provided limited insights into either Crohn\\'s disease or ulcerative colitis etiopathogenesis. In this update, we will summarize how the changing epidemiology of IBD associated with modernization can be reconciled with current concepts of disease mechanisms and will discuss studies of clinically significant comorbidity in IBD.

  19. History and philosophy of modern epidemiology

    DEFF Research Database (Denmark)

    Andersen, Hanne

    2012-01-01

    Epidemiological studies of chronic diseases began around the mid-20th century. Contrary to the infectious disease epidemiology which had prevailed at the beginning of the 20th century and which had focused on single agents causing individual diseases, the chronic disease epidemiology which emerge...

  20. Epidemiology of subtypes of depression

    DEFF Research Database (Denmark)

    Kessing, L V

    2007-01-01

    depression, dysthymia, and subsyndromal states; the association between stressful life events and depression appears to diminish with the number of depressive episodes. Finally, recent genetic findings are congruent with a model indicating that the majority of depressions develop in the interplay between...... genes and stressful experiences, whereas 'reactive' depressions and 'endogenous' depressions apparently exist at a lower prevalence. CONCLUSION: Further longitudinal, analytical, and genetic epidemiologic studies are needed to reveal which conditions are mild and transient, and which may be precursors......OBJECTIVE: There is a general clinical impression that depression differs qualitatively from non-depressive conditions, and that it can be identified as a categorical entity. In contrast, epidemiological studies support the view that depression is dynamic in nature and develops on a continuous...

  1. "Epidemiological criminology": coming full circle.

    Science.gov (United States)

    Akers, Timothy A; Lanier, Mark M

    2009-03-01

    Members of the public health and criminal justice disciplines often work with marginalized populations: people at high risk of drug use, health problems, incarceration, and other difficulties. As these fields increasingly overlap, distinctions between them are blurred, as numerous research reports and funding trends document. However, explicit theoretical and methodological linkages between the 2 disciplines remain rare. A new paradigm that links methods and statistical models of public health with those of their criminal justice counterparts is needed, as are increased linkages between epidemiological analogies, theories, and models and the corresponding tools of criminology. We outline disciplinary commonalities and distinctions, present policy examples that integrate similarities, and propose "epidemiological criminology" as a bridging framework.

  2. Viral marketing as epidemiological model

    OpenAIRE

    Rodrigues, Helena Sofia; Fonseca, Manuel

    2015-01-01

    In epidemiology, an epidemic is defined as the spread of an infectious disease to a large number of people in a given population within a short period of time. In the marketing context, a message is viral when it is broadly sent and received by the target market through person-to-person transmission. This specific marketing communication strategy is commonly referred as viral marketing. Due to this similarity between an epidemic and the viral marketing process and because the understanding of...

  3. Epidemiologic perspectives in radiation carcinogenesis

    International Nuclear Information System (INIS)

    Jablon, S.

    1984-01-01

    Epidemiological studies can tell much about carcinogenic effects at large doses, but not at small. To embark on large, long-term, expensive follow-up studies to learn something of scientific value about the effects of low doses-an average of three rads, say - is to waste time, effort, and money. It would be a fruitless effort even if the only problem to overcome was sampling variability - but it is not

  4. EPIDEMIOLOGICAL EVALUATION OF COLORECTAL CANCER

    OpenAIRE

    B. Shafayan M. Keyhani

    2003-01-01

    This study was carried out to analyze certain epidemiological variations in Iranian patients with colorectal cancer. (CRC): From March 1981 up to March 1993, 103 patients were analyzed retrospectively for age, gender, marital state, job, nutritional habits, presenting symptoms and histopathological features. Most of the patients with colorectal cancer were male, age range 20-75 (mean 56), 25.4 percent were long-term smokers and bleeding was the most common symptom. The rectum was the most com...

  5. Causal diagrams in systems epidemiology

    Directory of Open Access Journals (Sweden)

    Joffe Michael

    2012-03-01

    Full Text Available Abstract Methods of diagrammatic modelling have been greatly developed in the past two decades. Outside the context of infectious diseases, systematic use of diagrams in epidemiology has been mainly confined to the analysis of a single link: that between a disease outcome and its proximal determinant(s. Transmitted causes ("causes of causes" tend not to be systematically analysed. The infectious disease epidemiology modelling tradition models the human population in its environment, typically with the exposure-health relationship and the determinants of exposure being considered at individual and group/ecological levels, respectively. Some properties of the resulting systems are quite general, and are seen in unrelated contexts such as biochemical pathways. Confining analysis to a single link misses the opportunity to discover such properties. The structure of a causal diagram is derived from knowledge about how the world works, as well as from statistical evidence. A single diagram can be used to characterise a whole research area, not just a single analysis - although this depends on the degree of consistency of the causal relationships between different populations - and can therefore be used to integrate multiple datasets. Additional advantages of system-wide models include: the use of instrumental variables - now emerging as an important technique in epidemiology in the context of mendelian randomisation, but under-used in the exploitation of "natural experiments"; the explicit use of change models, which have advantages with respect to inferring causation; and in the detection and elucidation of feedback.

  6. Causal diagrams in systems epidemiology.

    Science.gov (United States)

    Joffe, Michael; Gambhir, Manoj; Chadeau-Hyam, Marc; Vineis, Paolo

    2012-03-19

    Methods of diagrammatic modelling have been greatly developed in the past two decades. Outside the context of infectious diseases, systematic use of diagrams in epidemiology has been mainly confined to the analysis of a single link: that between a disease outcome and its proximal determinant(s). Transmitted causes ("causes of causes") tend not to be systematically analysed.The infectious disease epidemiology modelling tradition models the human population in its environment, typically with the exposure-health relationship and the determinants of exposure being considered at individual and group/ecological levels, respectively. Some properties of the resulting systems are quite general, and are seen in unrelated contexts such as biochemical pathways. Confining analysis to a single link misses the opportunity to discover such properties.The structure of a causal diagram is derived from knowledge about how the world works, as well as from statistical evidence. A single diagram can be used to characterise a whole research area, not just a single analysis - although this depends on the degree of consistency of the causal relationships between different populations - and can therefore be used to integrate multiple datasets.Additional advantages of system-wide models include: the use of instrumental variables - now emerging as an important technique in epidemiology in the context of mendelian randomisation, but under-used in the exploitation of "natural experiments"; the explicit use of change models, which have advantages with respect to inferring causation; and in the detection and elucidation of feedback.

  7. Biomarkers in Prostate Cancer Epidemiology

    Directory of Open Access Journals (Sweden)

    Mudit Verma

    2011-09-01

    Full Text Available Understanding the etiology of a disease such as prostate cancer may help in identifying populations at high risk, timely intervention of the disease, and proper treatment. Biomarkers, along with exposure history and clinical data, are useful tools to achieve these goals. Individual risk and population incidence of prostate cancer result from the intervention of genetic susceptibility and exposure. Biochemical, epigenetic, genetic, and imaging biomarkers are used to identify people at high risk for developing prostate cancer. In cancer epidemiology, epigenetic biomarkers offer advantages over other types of biomarkers because they are expressed against a person’s genetic background and environmental exposure, and because abnormal events occur early in cancer development, which includes several epigenetic alterations in cancer cells. This article describes different biomarkers that have potential use in studying the epidemiology of prostate cancer. We also discuss the characteristics of an ideal biomarker for prostate cancer, and technologies utilized for biomarker assays. Among epigenetic biomarkers, most reports indicate GSTP1 hypermethylation as the diagnostic marker for prostate cancer; however, NKX2-5, CLSTN1, SPOCK2, SLC16A12, DPYS, and NSE1 also have been reported to be regulated by methylation mechanisms in prostate cancer. Current challenges in utilization of biomarkers in prostate cancer diagnosis and epidemiologic studies and potential solutions also are discussed.

  8. Panel 1: Epidemiology and Diagnosis.

    Science.gov (United States)

    Homøe, Preben; Kværner, Kari; Casey, Janet R; Damoiseaux, Roger A M J; van Dongen, Thijs M A; Gunasekera, Hasantha; Jensen, Ramon G; Kvestad, Ellen; Morris, Peter S; Weinreich, Heather M

    2017-04-01

    Objective To create a literature review between 2011 and June 1, 2015, on advances in otitis media (OM) epidemiology and diagnosis (including relevant audiology studies). Data Sources Electronic search engines (PubMed, EMBASE, and Cochrane Library) with a predefined search strategy. Review Methods Articles with appropriate epidemiologic methodology for OM, including acute mastoiditis and eustachian tube dysfunction. Items included OM worldwide and in high-risk populations, OM-related hearing loss, news in OM diagnostics, prenatal risk factors and comorbidities, postnatal risk factors, genetics, microbiological epidemiology, guidelines, and quality of life. Conclusions Diagnostic evidence and genetic studies are increasing; guidelines are introduced worldwide; and there is evidence of benefit of pneumococcal conjugate vaccines. New risk factors and comordities are identified in the study period, and quality of life is affected in children and their families. Implications for Practice Chronic suppurative OM occurs worldwide and contributes to lifelong hearing loss. Uniform definitions are still lacking and should be provided. An association between HIV and chronic suppurative OM has been found. Tympanometry is recommended for diagnosis, with or without pneumatic otoscopy. Video otoscopy, algorithms, and validated questionnaires may assist clinicians. Childhood obesity is associated with OM. Heritability accounts for 20% to 50% of OM diagnoses. OM-prone children seem to produce weaker immunologic responses to pneumococcal conjugate vaccines. Clinicians tend to individualize treatment without adhering to guidelines.

  9. Diseño de un instrumento educativo para pacientes con lumbalgia crónica inespecífica atendidos en Atención Primaria

    Directory of Open Access Journals (Sweden)

    Juan Luis Díaz-Cerrillo

    2015-02-01

    Full Text Available Evidencias científicas actuales sobre el manejo de la lumbalgia crónica inespecífica ponen de relieve los beneficios del ejercicio físico. Este objetivo es frecuentemente minado por déficits educativos en materias relacionadas con la naturaleza multifactorial y benigna del dolor lumbar inespecífico, los cuales constituyen auténticos factores de riesgo psicosocial para la cronificación. Su perversa influencia podría interferir no solo con la decisión individual de adoptar conductas de afrontamiento más adaptativas, sino también, con los mecanismos endógenos de neuromodulación del dolor. Así, las estrategias educativas y el control de dichos factores se han convertido en objetivos relevantes a incorporar en el manejo del trastorno y en las directrices de investigación. Este trabajo presenta los modelos teóricos y las bases científicas sobre los que se ha sustentado el diseño de un instrumento educativo para pacientes con lumbalgia crónica inespecífica atendidos en Fisioterapia de Atención Primaria. Su estructuración, contenido y objetivos también son presentados.

  10. Jurisdicción y medios alternativos de resolución de conflictos: una opción para las cuestiones ambientales

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Lunelli

    2014-10-01

    Full Text Available A medida que las sociedades se fueron tornando más complejas, comenzaron a surgir nuevas categorías de conflictos, como es el caso de los conflictos ambientales. Sin embargo, el sistema procesal vigente todavía se rige por un ordenamiento jurídico positivista, apegado fundamentalmente a las directrices enmarcadas en la ley, ya que en la actualidad se utiliza la misma estructura judicial para resolver todo tipo de apremios. Como resultado de ello, se observa una deficiencia, por parte del Estado, en tutelar los nuevos derechos que surgen en una sociedad en constante evolución. Dado este contexto, el presente trabajo plantea la necesidad de utilizar medios alternativos de resolución de controversias, tales como la mediación-conciliación como opciones viables para poner fin a los conflictos ambientales, y con ello obtener una solución mediante medidas específicas al caso concreto.

  11. Epidemiología de las lesiones por quemaduras Epidemiology of lesions provoked by burns

    Directory of Open Access Journals (Sweden)

    José A Viñas Díaz

    2009-12-01

    Full Text Available Las quemaduras son una causa importante de muerte accidental, solo superadas por los accidentes de automóviles. Con el objetivo de conocer algunos aspectos de la epidemiología de las quemaduras en Pediatría en la provincia de Pinar del Río (Cuba, se realizó una investigación transversal, descriptiva que abarcó 26 casos con edades comprendidas entre 0-18 años, ingresados con el diagnóstico de quemaduras no intencionales en el Servicio de Caumatología del Hospital "Abel Santamaría Cuadrado" Pinar del Río. (Cuba, durante el año 2006. Se revisaron las historias clínicas y para el tratamiento de la información se utilizó la estadística descriptiva, determinando la relación entre las variables estudiadas. Se encontró que el grupo más afectado era el menor de 15 años (96.2 %, en la cocina (42.3 %por escaldadura, por líquidos calientes (53,8%. No hubo fallecidos. La prevención es un aspecto decisivo para evitar este tipo de accidente.Burns are one of the most important causes of accidental death, only exceeded by traffic accidents. This paper is aimed at knowing issues related to the epidemiology of burns in pediatric ages in Pinar del Rio Province, Cuba. A cross-sectional, descriptive study was conducted with 26 burned children (0-18 years old admitted to the Caumatology Service at "Abel Santamaria" General University Hospital, during 2006. Clinical records were the source of information and descriptive statistics for showing frequencies and X² at 95 % of certainty was used for homogeneity. The group of ages younger than 15 years old was the most affected (96.2 %. Burns were mainly produced at the kitchen (42, 3 % by hot liquids (scalds (53.8 %, among other causes without mortality. Prevention is a decisive action to avoid this type of accident.

  12. Epidemiology

    International Nuclear Information System (INIS)

    Hubert, D.

    2009-01-01

    Because of the concern of people, a study of mortality has previously been conducted in two Pennsylvania counties located near manufacturing and reprocessing plants of nuclear materials over the period 1950-1995. No excessive mortality has been identified in the population exposed counties in comparison to control counties. The current study is the continuation of the previous study of mortality over a period of eight additional years (up to 2004) and the addition of a study of cancer incidence over the period 1990-2004 and mortality for causes out of cancer from 1996 to 2004. Method: The population of each county of the study was compared to the population of three control counties selected according to socioeconomic and demographic characteristics, the same way as in the previous study. The demographic, mortality and incidence data for the different counties have been earned at the state of Pennsylvania. Results: over the period 1996-2004, mortality from cancer (10 457 deaths) in the two counties studied was comparable to that of six control counties (relative risk .97 [95% CI .94 -. 99]) and previous results. Similarly, the incidence of cancer was similar in the counties studied (39350 cases of cancer) and the control counties (relative risk .99 [95% CI .97-1.00]). The number of deaths unrelated to cancer was 36 565, very close to the expected number (relative risk .99 [95% CI 1.01-1.01]). Conclusion: Overall, no increase in cancer or non-cancer disease could be attributed to living in counties that had manufacturing and reprocessing plants of nuclear materials. (N.C.)

  13. Amebiasis: Epidemiología y Tratamiento

    Directory of Open Access Journals (Sweden)

    Alberto Albornoz Plata

    1986-08-01

    eliminadores” o portadores sanos de quistes, los cuales sin ser enfermos sí necesitan tratamiento específico por el peligro que representan para la comunidad por poder diseminar la enfermedad y en un momento dado poder padecer la forma activa o invasora de la amebiasis; este solo aspecto complica aún más la epidemiología y la profilaxis de esta parasitosis.

    Para Colombia, por métodos coproacópicos, se han citado distintas cifras: 23.6% de acuerdo con la Investigación Nacional de Morbilidad efectuada en 1965- 1966 (2, cifra igual a la encontrada por una comisión de la Sociedad Colombiana de Gastroenterología (3 del 23.67 % sobre 138.193 observaciones verificadas en 3 zonas distintas del país; fría, templada y cálida (véase el cuadro que se anexa. Estas dos cifras guardan relación estadística con otra reciente, obtenida por el método de serodiagnsotico del 33 %encontrada en reclutas del ejército (sobre 2.963 casos por G.R. Healy...

  14. Epidemiology, molecular epidemiology, and risk factors for renal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Chiara Paglino

    2011-12-01

    Full Text Available Despite only accounting for approximately 2% of all new primary cancer cases, renal cell carcinoma (RCC incidence has dramatically increased over time. Incidence rates vary greatly according to geographic areas, so that it is extremely likely that exogenous risk factors could play an important role in the development of this cancer. Several risk factors have been linked with RCC, including cigarette smoking, obesity, hypertension (and antihypertensive drugs, chronic kidney diseases (also dialysis and transplantation, as well as the use of certain analgesics. Furthermore, although RCC has not generally been considered an occupational cancer, several types of occupationally-derived exposures have been implicated in its pathogenesis. These include exposure to asbestos, chlorinated solvents, gasoline, diesel exhaust fumes, polycyclic aromatic hydrocarbons, printing inks and dyes, cadmium and lead. Finally, families with a predisposition to the development of renal neoplasms were identified and the genes involved discovered and characterized. Therefore, there are now four well-characterized, genetically determined syndromes associated with an increased incidence of kidney tumors, i.e., Von Hippel Lindau (VHL, Hereditary Papillary Renal Carcinoma (HPRC, Birt-Hogg-Dubé Syndrome (BHD, and Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC. This review will address present knowledge about the epidemiology, molecular epidemiology and risk factors of RCC.

  15. Statistical significance of epidemiological data. Seminar: Evaluation of epidemiological studies

    International Nuclear Information System (INIS)

    Weber, K.H.

    1993-01-01

    In stochastic damages, the numbers of events, e.g. the persons who are affected by or have died of cancer, and thus the relative frequencies (incidence or mortality) are binomially distributed random variables. Their statistical fluctuations can be characterized by confidence intervals. For epidemiologic questions, especially for the analysis of stochastic damages in the low dose range, the following issues are interesting: - Is a sample (a group of persons) with a definite observed damage frequency part of the whole population? - Is an observed frequency difference between two groups of persons random or statistically significant? - Is an observed increase or decrease of the frequencies with increasing dose random or statistically significant and how large is the regression coefficient (= risk coefficient) in this case? These problems can be solved by sttistical tests. So-called distribution-free tests and tests which are not bound to the supposition of normal distribution are of particular interest, such as: - χ 2 -independence test (test in contingency tables); - Fisher-Yates-test; - trend test according to Cochran; - rank correlation test given by Spearman. These tests are explained in terms of selected epidemiologic data, e.g. of leukaemia clusters, of the cancer mortality of the Japanese A-bomb survivors especially in the low dose range as well as on the sample of the cancer mortality in the high background area in Yangjiang (China). (orig.) [de

  16. Molecular Epidemiology of Heart Failure

    Directory of Open Access Journals (Sweden)

    J. Gustav Smith, MD, PhD

    2017-12-01

    Full Text Available Heart failure (HF is the end-stage of all heart disease and arguably constitutes the greatest unmet therapeutic need in cardiovascular medicine today. Classic epidemiological studies have established clinical risk factors for HF, but the cause remains poorly understood in many cases. Biochemical analyses of small case-control series and animal models have described a plethora of molecular characteristics of HF, but a single unifying pathogenic theory is lacking. Heart failure appears to result not only from cardiac overload or injury but also from a complex interplay among genetic, neurohormonal, metabolic, inflammatory, and other biochemical factors acting on the heart. Recent development of robust, high-throughput tools in molecular biology provides opportunity for deep molecular characterization of population-representative cohorts and HF cases (molecular epidemiology, including genome sequencing, profiling of myocardial gene expression and chromatin modifications, plasma composition of proteins and metabolites, and microbiomes. The integration of such detailed information holds promise for improving understanding of HF pathophysiology in humans, identification of therapeutic targets, and definition of disease subgroups beyond the current classification based on ejection fraction which may benefit from improved individual tailoring of therapy. Challenges include: 1 the need for large cohorts with deep, uniform phenotyping; 2 access to the relevant tissues, ideally with repeated sampling to capture dynamic processes; and 3 analytical issues related to integration and analysis of complex datasets. International research consortia have formed to address these challenges and combine datasets, and cohorts with up to 1 million participants are being collected. This paper describes the molecular epidemiology of HF and provides an overview of methods and tissue types and examples of published and ongoing efforts to systematically evaluate molecular

  17. ASPECTOS AMBIENTALES EN LA EXPERIMENTACIÓN QUÍMICA PARA PREVENIR RIESGOS A LA SALUD Y AL AMBIENTE

    Directory of Open Access Journals (Sweden)

    María O. Peña O.

    2011-01-01

    Full Text Available Un aspecto ambiental se considera como cualquier material o elemento físico o químico que el hombre arroja al agua, al aire y al suelo o que interactúe con el ambiente y propicie un riesgo para la salud y para el medio ambiente. Los residuos originados durante el desarrollo de actividades relacionadas con la experimentación química, aunque en una proporción menor que en un proceso industrial, ellos pueden ser residuos peligrosos al medio ambiente. Los aspectos ambientales se asocian con las actividades de generación de residuos, derrames, emisión a la atmósfera, el consumo de recursos naturales y ruido. Este estudio tuvo como objetivo proponer directrices para identificar y clasificar a los residuos que son generados en una experimentación química e introducir aspectos de seguridad para la salud y para el medio ambiente dentro de los procedimientos analíticos. Se inició con una evaluación diagnóstica sobre el conocimiento de la normativa en materia de gestión de los residuos o desechos, dirigida a técnicos y profesores que realizan actividades en ocho laboratorios para la enseñanza de la Química. Se siguió con la selección de un procedimiento analítico, como caso estudio, para revisar y aplicar estrategias de reusar, reciclar y reducir la generación de los residuos. Se encontró un desconocimiento de la normativa ambiental, representada por el 73% de los encuestados y un escaso tratamiento de residuos. Se concluye que la extensión de aspectos ambientales en los procedimientos analíticos puede ayudar a prevenir la contaminación ambiental, a fortalecer aspectos toxicológicos, de seguridad y de prevención de riesgos laborales.

  18. Some aspects of cancer epidemiology

    International Nuclear Information System (INIS)

    Lilienfeld, A.M.

    1982-01-01

    Epidemiolgic studies have strongly suggested that a vast majority (80-90%) of cancers are caused by radiation, chemical and biologic agents; the remainder result from endogenous or genetic factors. Biologically, cancer is most probably the end result of a complex multistage process and therefore may be due to a sequence of exposures to different agents at each of these stages. This emphasizes the need to stress the study of interactions in epidemiologic studies to a greater extent than has been done thus far. Examples of the importance of interactions in several types of cancer are presented

  19. An introduction to mathematical epidemiology

    CERN Document Server

    Martcheva, Maia

    2015-01-01

    The book is a comprehensive, self-contained introduction to the mathematical modeling and analysis of infectious diseases. It includes model building, fitting to data, local and global analysis techniques. Various types of deterministic dynamical models are considered: ordinary differential equation models, delay-differential equation models, difference equation models, age-structured PDE models and diffusion models. It includes various techniques for the computation of the basic reproduction number as well as approaches to the epidemiological interpretation of the reproduction number. MATLAB code is included to facilitate the data fitting and the simulation with age-structured models.

  20. Intrathoracic neoplasia: Epidemiology and etiology

    Energy Technology Data Exchange (ETDEWEB)

    Weller, R.E.

    1992-05-01

    Neoplasms of the thorax encompass those derived from the thoracic wall, trachea, mediastinum, lungs and pleura. They represent a wide variety of lesions including benign and malignant tumors arising from many tissues. The large surface area, 60 to 90 m{sup 2} in man, represented by the respiratory epithelium and associated thoracic structures are ideal targets for carcinogens carried by inspired air. The topic of discussion in this report is the epidemiology, etiology, and mechanisms of spontaneous intrathoracic neoplasia in animals and man. Much of what we know or suspect about thoracic neoplasia in animals has been extrapolated from experimentally-induced neoplasms.

  1. Epidemiology: past, present and future.

    Science.gov (United States)

    Kesteloot, H

    2004-01-01

    Epidemiology in the past was concerned essentially by the study of infectious diseases which were the cause of huge mortalities especially since urbanisation was initiated. Epidemics of pest, typhus, cholera, influenza a.o. were common. The epidemics were halted by better hygiene, vaccination and antibiotics. Since the second world war epidemiology was dominated by an "epidemic" of new chronic diseases, especially heart disease and cancer. This was due to an increase in life span and to an increase in smoking habits and in the intake of saturated fat and a too small intake of fruit and vegetables combined with a too high intake of salt (NaCl). Gradually epidemiology evolved as the study of the causes, the distribution, the risk factors and the prevention of chronic diseases, but also including accidents, suicide, depression a.o., diseases with a mass occurrence at the population level. The importance of nutrition as a determinant of health gradually became recognized, but remains undervalued by the medical profession. Mortality at the population level follows some simple mathematical laws and can be represented accurately (r2>0.99) between the ages of 35 and 84 year by either Gompertz equations (ln mortality versus age) or by a polynomial equation (ln mortality versus age, age2). This is valid for all populations and both sexes and remains valid at times of great and rapid changes in mortality. This shows that measures for prevention should be directed towards the total population. The future of epidemiology should be directed towards the slowing of the ageing process at the population level by a healthy life style consisting of: not smoking, avoiding obesity, a fair amount of physical activity and a healthy nutrition i.e little salt, little saturated fat, an adequate amount of omega-3 fatty acids and a large amount of fruit and vegetables, with an occasional glass of red wine. This contains the secret of a long and healthy life. Conceptually it will be important

  2. Fertility and pregnancy: an epidemiologic perspective

    National Research Council Canada - National Science Library

    Wilcox, Allen J

    2010-01-01

    .... Weaving together history, biology, obstetrics, pediatrics, demography, infectious diseases, molecular genetics, and evolutionary biology, Allen Wilcox brings a fresh coherence to the epidemiologic...

  3. Clinical Epidemiology Unit - overview of research areas

    Science.gov (United States)

    Clinical Epidemiology Unit (CEU) conducts etiologic research with potential clinical and public health applications, and leads studies evaluating population-based early detection and cancer prevention strategies

  4. Epidemiology: second-rate science?

    Science.gov (United States)

    Parascandola, M

    1998-01-01

    In recent years epidemiology has come under increasing criticism in regulatory and public arenas for being "unscientific." The tobacco industry has taken advantage of this, insisting for decades that evidence linking cigarettes and lung cancer falls short of proof. Moreover, many epidemiologists remain unduly skeptical and self-conscious about the status of their own causal claims. This situation persists in part because of a widespread belief that only the laboratory can provide evidence sufficient for scientific proof. Adherents of this view erroneously believe that there is no element of uncertainty or inductive inference in the "direct observation" of the laboratory researcher and that epidemiology provides mere "circumstantial" evidence. The historical roots of this attitude can be traced to philosopher John Stuart Mill and physiologist Claude Bernard and their influence on modern experimental thinking. The author uses the debate over cigarettes and lung cancer to examine ideas of proof in medical science and public health, concluding that inductive inference from a limited sample to a larger population is an element in all empirical science.

  5. Epidemiology of Clostridium difficile Infection

    Science.gov (United States)

    DePestel, Daryl D.; Aronoff, David M.

    2014-01-01

    There has been dramatic change in the epidemiology of Clostridium difficile infection (CDI) since the turn of the 21st Century noted by a marked increase in incidence and severity, occurring at a disproportionately higher frequency in older patients. Historically considered a nosocomial infection associated with antibiotic exposure, CDI has now also emerged in the community in populations previously considered low risk. Emerging risk factors and disease recurrence represent continued challenges in the management of CDI. The increased incidence and severity associated with CDI has coincided with the emergence and rapid spread of a previously rare strain, ribotype 027. Recent data from the U.S. and Europe suggest the incidence of CDI may have reached a crescendo in recent years and is perhaps beginning to plateau. The acute-care direct costs of CDI were estimated to be $4.8 billion in 2008. However, nearly all the published studies have focused on CDI diagnosed and treated in acute-care hospital setting and fail to measure the burden outside the hospital, including recently discharged patients, outpatients, and those in long-term care facilities. Enhanced surveillance methods are needed to monitor the incidence, identify populations at risk, and characterize the molecular epidemiology of strains causing CDI. PMID:24064435

  6. Childhood vitiligo: Clinical epidemiological profile

    Directory of Open Access Journals (Sweden)

    Asmae Lahlou

    2017-07-01

    Full Text Available Objective: To study the clinical and the epidemiologic profiles of childhood vitiligo. Patients and Methods: We prospectively analyzed the clinical data of children with vitiligo presented to the dermatology derpartement at University Hospital – Fès for 5 years from May 2011 to May 2016. This study included 31 patients. All patients were assessed for the natural history, clinical characteristics, family history, and associated abnormalities of vitiligo. Results: Of the 31 children with vitiligo 9 (29,03% were boys and 21 (67.74% were girls. The mean age of onset of the vitiligo was 10 years. The mean duration of the disease was 38,9 weeks. The most common type of vitiligo was vitiligo vulgaris (49.5% followed by focal vitiligo (39%, acrofacial vitiligo (32%, and segmental vitiligo (16% The most frequent site of onset was the extremities followed by the head and the neck, then the trunk and the genitalia. Of the 31 children with vitiligo, 39% had a family history and 4 % had an antecedent of autoimmune diesease like le diabète, une thyroïdite, l’anémie et le psoriasis, retrouvé. Conclusion: Our children have a strong family history of vitiligo and they are developing the disease at a slightly older age compared with those of other studies; however, other epidemiologic features appear to be similar to those reported in the previously published studies.

  7. Epidemiologic research program: Selected bibliography

    International Nuclear Information System (INIS)

    1993-05-01

    This bibliography is a current listing of scientific reports from epidemiologic and related activities sponsored by the Department of Energy. The Office of Epidemiology and Health Surveillance now is the departmental focal point for these activities and any others relating to the study of human health effects. The Office's mission is evolving to encompass the new role of the Department in environmental restoration, weapons dismantlement and nuclear material storage, and development of new energy technologies. Publications in these areas will be included in future editions of the bibliography. The present edition brings the listing up to date, and should facilitate access to specific reports. The program has been divided into several general areas of activity: the Radiation Effects Research Foundation, which supports studies of survivors of the atomic weapons in Hiroshima and Nagasaki; mortality and morbidity studies of DOE workers; studies on internally deposited alpha emitters; medical/histologic studies; studies on the genetic aspects of radiation damage; community health surveillance studies; and the development of computational techniques and of databases to make the results as widely useful as possible

  8. Biological diversity variations of pediatric acute leukemia in Brazil: contribution of immunophenotypic profiles to epidemiological studies Diversidades biológicas da leucemia aguda em crianças no Brasil: contribuição de perfis imunofenotípicos para estudos epidemiológicos

    Directory of Open Access Journals (Sweden)

    Maria S. Pombo-de-Oliveira

    2005-03-01

    Full Text Available We describe the demographic and biological characteristics of 1,459 children with acute leukemia in Brazil to compare the effect of immunophenotypic differences with environmental factors that might be involved in the etiology of acute lymphoblastic leukemia (ALL. Combined morphological and immunological classifications were available for 96% of cases. Of these, 55% were B cell precursor ALL comprising pro-B ALL and c-ALL, 15% T-ALL and 1.6% mature B-ALL. The proportion of Bp and T-ALL differed by race with 59% of whites being Bp-ALL and 60.7% of non-whites being T-ALL. Further inspection of these data revealed that the proportions of whites in each type (Bp/T-cell ALL are almost identical in older children (60.3% and 59.3% respectively but differ substantially in younger cases (Os autores descrevem as características biológicas de 1.459 crianças com leucemias agudas no Brasil, para comparar os efeitos de diferentes perfis imunofenotípicos com fatores ambientais que podem estar associados à etiologia das leucemias linfoblásticas agudas (LLA. As classificações morfológicas e imunofenotípicas combinadas foram aplicadas em 96% dos casos. Nestes, 55% foram classificados como LLA de células B precursoras (LLA-Bp que compreendem LLA-pro-B e LLA-comum, 15% LLA-T, e 1,6% LLA-B. A proporção de LLA-Bp e LLA-T difere entre si quanto à raça, com 59% das LLA-Bp em crianças brancas, enquanto 60,7% LLA-T em crianças não-brancas. No entanto, as análises proporcionais de brancos versus não brancos para cada subtipo, quando ajustadas por idade, são semelhantes em crianças maiores de 6 anos (60,3% LLA-Bp e 59,3% LLA-T, mas diferem substancialmente em crianças menores, com 63,6% de LLA-Bp e 37,3% de LLA-T em brancos (0,0001. Estes resultados são consistentes com excesso de LLA-Bp em crianças brancas mais jovens, embora a distribuição entre LLA-Bp e LLA-T em cada região seja semelhante sem significado estatístico. As taxas de incid

  9. Communications Received from Certain Member States Regarding Guidelines for Transfers of Nuclear-related Dual-use Equipment, Materials, Software and Related Technology; Comunicaciones recibidas de diversos Estados Miembros relativas a las directrices para las transferencias de equipos, materiales y programas informaticos (software) de doble uso del ambito nuclear y tecnologia relacionada

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-04-11

    The Director General of the International Atomic Energy Agency has received Notes Verbales, dated 1 December 2005, from the Resident Representatives to the Agency of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, Croatia, Czech Republic, Estonia, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, New Zealand, Poland, Portugal, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, relating to transfers of nuclear-related dual-use equipment, materials, software and related technology [Spanish] El Director General del Organismo Internacional de Energia Atomica ha recibido Notas verbales de fecha 1 de diciembre de 2005 de los Representantes Permanentes ante el Organismo de Alemania, Argentina, Australia, Austria, Belarus, Belgica, Brasil, Bulgaria, Canada, Croacia, Eslovenia, Espana, Estados Unidos de America, Estonia, Finlandia, Francia, Grecia, Hungria, Irlanda, Italia, Japon, Letonia, Lituania, Luxemburgo, Malta, Nueva Zelandia, Paises Bajos, Polonia, Portugal, Reino Unido de Gran Bretana e Irlanda del Norte, Republica Checa, Republica de Corea, Sudafrica, Suecia, Suiza, Turquia y Ucrania relativas a las transferencias de equipos, materiales y programas informaticos de doble uso del ambito nuclear y tecnologia relacionada.

  10. Communication received from the Permanent Mission of Denmark to the Agency regarding Guidelines for the Export of Nuclear Material, Equipment and Technology; Comunicacion recibida de la Mision Permanente de Dinamarca ante el Organismo relativa a las directrices para la exportacion de materiales, equipos y tecnologia nucleares

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-01-02

    The Director General of the International Atomic Energy Agency has received Notes Verbales, dated 1 December 2005, from the Resident Representatives to the Agency of Argentina, Australia, Austria, Belarus, Belgium, Brazil, Bulgaria, Canada, China, Croatia, Czech Republic, Finland, France, Germany, Greece, Hungary, Ireland, Italy, Japan, Republic of Korea, Latvia, Lithuania, Luxembourg, Malta, the Netherlands, New Zealand, Poland, Portugal, Slovenia, South Africa, Spain, Sweden, Switzerland, Turkey, Ukraine, the United Kingdom of Great Britain and Northern Ireland and the United States of America, relating to the export of nuclear material, equipment and technology [Spanish] El Director General ha recibido una nota verbal de la Mision Permanente de Dinamarca, de fecha 1 de diciembre de 2005, en la que se facilita informacion sobre las politicas y practicas del Gobierno de Dinamarca con respecto a la exportacion de materiales, equipos y tecnologia nucleares. Atendiendo a los deseos expresados al final de la nota verbal, se adjunta al presente documento el texto de dicha nota. El apendice a que se hace referencia en la nota verbal se publico previamente como INFCIRC/254/Rev.7/pt.1.

  11. Estrategias para negociaciones exitosas.

    OpenAIRE

    José B. Parra V; Evelinda Santiago J.; Misael Murillo M.; Candy Atonal N.

    2010-01-01

    Las estrategias de negociación son herramientas para disminuir conflictos o para intercambiar bienes y servicios. Una negociación exitosa crea relaciones de solidaridad y propicia reciprocidad, cooperación y confianza para quienes tendrán relaciones permanentes de negociación con beneficios para ambas partes. Una estrategia de negociación exitosa requiere manejar el desarrollo del ambiente social del grupo de personas, con la finalidad de tener presente las fronteras que no pueden irrumpirse....

  12. The New Epidemiology--A Challenge to Health Administration. Issues in Epidemiology for Administration.

    Science.gov (United States)

    Crichton, Anne, Ed.; Neuhauser, Duncan, Ed.

    The role of epidemiology in health administration is considered in 11 articles, and three course descriptions and a bibliography are provided. Titles and authors include the following: "The Need for Creative Managerial Epidemiology" (Gary L. Filerman); "The Growing Role of Epidemiology in Health Administration" (Maureen M.…

  13. [Causal analysis approaches in epidemiology].

    Science.gov (United States)

    Dumas, O; Siroux, V; Le Moual, N; Varraso, R

    2014-02-01

    Epidemiological research is mostly based on observational studies. Whether such studies can provide evidence of causation remains discussed. Several causal analysis methods have been developed in epidemiology. This paper aims at presenting an overview of these methods: graphical models, path analysis and its extensions, and models based on the counterfactual approach, with a special emphasis on marginal structural models. Graphical approaches have been developed to allow synthetic representations of supposed causal relationships in a given problem. They serve as qualitative support in the study of causal relationships. The sufficient-component cause model has been developed to deal with the issue of multicausality raised by the emergence of chronic multifactorial diseases. Directed acyclic graphs are mostly used as a visual tool to identify possible confounding sources in a study. Structural equations models, the main extension of path analysis, combine a system of equations and a path diagram, representing a set of possible causal relationships. They allow quantifying direct and indirect effects in a general model in which several relationships can be tested simultaneously. Dynamic path analysis further takes into account the role of time. The counterfactual approach defines causality by comparing the observed event and the counterfactual event (the event that would have been observed if, contrary to the fact, the subject had received a different exposure than the one he actually received). This theoretical approach has shown limits of traditional methods to address some causality questions. In particular, in longitudinal studies, when there is time-varying confounding, classical methods (regressions) may be biased. Marginal structural models have been developed to address this issue. In conclusion, "causal models", though they were developed partly independently, are based on equivalent logical foundations. A crucial step in the application of these models is the

  14. Retos clave para lograr elevar la competitividad empresarial en México

    OpenAIRE

    Eugenio Guzman Soria; Juvencio Hernández Martínez; Daniel Hernández Soto

    2007-01-01

    La competitividad de la economía mexicana durante los últimos años refleja un claro retroceso en comparación con economías también catalogadas en desarrollo (Brasil, India, China, entre otras), lo anterior ha llevado a los especialistas nacionales a analizar y discutir las diferentes directrices económicas, tecnológicas e instituciones que ayudarían al país a revertir tal situación. Este trabajo presenta, discute y analiza las siete principales directrices sobre las cuales el gobierno, instit...

  15. Inclusão social da pessoa com deficiência: conquistas, desafios e implicações para a enfermagem La inclusión social de la persona con deficiencia: conquistas, desafíos y implicaciones para la enfermería Social inclusion of disable people: achievements, challenges and implications for the nursing area

    Directory of Open Access Journals (Sweden)

    Inacia Sátiro Xavier de França

    2009-03-01

    Full Text Available Objetivou-se compreender o discurso das pessoas com deficiência acerca da concretude do processo de inclusão social e articular o discurso desses sujeitos com as diretrizes do Decreto nº 3.298/99. Foram entrevistadas seis pessoas com deficiência física, seis auditivos e seis visuais Os dados foram padronizados e categorizados em dois núcleos de sentidos: diretrizes pré-inclusivistas da pessoa com deficiência, e diretrizes inclusivistas da pessoa com deficiência. A perspectiva metodológica foi a análise de discurso. Conclui-se que esses sujeitos conquistaram legislação que assegura direitos de cidadania, mas existem desafios no campo da saúde, educação, profissionalização e da inserção no mercado de trabalho. Os enfermeiros reabilitadores precisam conhecer a vivência desses sujeitos e dos seus familiares para ajudá-los a buscar estratégias de enfrentamento dos problemas que afetam a sua inclusão e, conseqüentemente, a sua saúde.El objetivo de la investigación fue comprender el discurso de las personas con deficiencia acerca de cuán efectivo es el proceso de inclusión social y articular el discurso de eses sujetos con las directrices del Decreto nº 3.298/99. Fueron entrevistadas seis personas con deficiencia física, seis auditivos y seis visuales Los datos fueron estandarizados y clasificados en categorías en dos núcleos de sentidos: directrices pre-inclusivistas de la persona con deficiencia, y directrices inclusivistas de la persona con deficiencia. La perspectiva metodológica fue el análisis de discurso. Se concluye que eses sujetos conquistaron una legislación que asegura derechos de ciudadanía, sin embargo existen desafíos en el campo de la salud, educación, profesionalización y de la inserción en el mercado de trabajo. Los enfermeros que actúan en rehabilitación necesitan conocer la vivencia de eses sujetos y de sus familiares para ayudarlos a buscar estrategias de enfrentamiento de los problemas

  16. Epidemiology of extremity fractures in the Netherlands

    NARCIS (Netherlands)

    Beerekamp, M. S. H.; de Muinck Keizer, R. J. O.; Schep, N. W. L.; Ubbink, D. T.; Panneman, M. J. M.; Goslings, J. C.

    2017-01-01

    Insight in epidemiologic data of extremity fractures is relevant to identify people at risk. By analyzing age- and gender specific fracture incidence and treatment patterns we may adjust future policy, take preventive measures and optimize health care management. Current epidemiologic data on

  17. Complex epidemiological approach to human mutagenesis

    International Nuclear Information System (INIS)

    Czeizel, A.

    1980-01-01

    The main characteristics of the epidemiological approach are summarised and the criteria discussed for the adoption of this approach for the detection of human mutagenesis. Mutation monitoring systems are described and results of epidemiological studies of higher risk populations are presented. (C.F.)

  18. Maritim epidemiologi på Supercourse

    DEFF Research Database (Denmark)

    Jensen, Olaf

    2015-01-01

    Maritim epidemiologi er nu kommet med i samlingen af undervisningsmidler på ”Supercourse”. Der er oprettet en særlig mappe med Maritime Epidemiology og alle der har gode bidrag inden for området opfordres hermed til at publicere her. Supercourse er en samling af foredrag beregnet til at være en r...

  19. Retrospective study of epidemiological, clinicopathological and ...

    African Journals Online (AJOL)

    Retrospective study of epidemiological, clinicopathological and biological profils of 62 colorectal cancers cases in Jijel provence (Algeria) ... Our results were often compatible with the available literature and may provide reliable and relevant data on this disease. Key words: Colorectal cancer; Epidemiology; Therapy; ...

  20. Epidemiology, diagnosis and management of food allergy

    NARCIS (Netherlands)

    Le, T.T.M.

    2013-01-01

    This thesis describes the epidemiology, diagnosis and management of food allergy. Epidemiology This thesis shows that the prevalence of self-reported adverse food reactions in children and adults was high: 17-25% for all foods and 10-11% for 24 preselected, so-called priority foods. The prevalence

  1. Nephrogenic systemic fibrosis: epidemiology update

    DEFF Research Database (Denmark)

    Marckmann, P.

    2008-01-01

    Purpose of review The aim of this article is to outline the history of nephrogenic systemic fibrosis, a new and serious disease of patients with renal failure, and to give an update on its aetiology and prevalence. Recent findings Epidemiological and histochemical studies demonstrated....... Increasingly poor renal function, aberrations in calcium-phosphate metabolism and erythropoietin treatment seem to increase the risk of the disease and its severity. Up to 25-30% of patients with renal failure exposed to gadolinium-based contrast agents may develop nephrogenic systemic disease. The figure...... that gadolinium-containing contrast agents used for magnetic resonance imaging have an essential causative role in most, if not all, cases of nephrogenic systemic fibrosis. One particular agent, gadodiamide, caused the majority of cases, but gadopentetate dimeglumine has also been implicated in several cases...

  2. Epidemiological studies in mucus hypersecretion

    DEFF Research Database (Denmark)

    Vestbo, Jørgen

    2002-01-01

    Respiratory mucus in epidemiology has mainly been studied using standardized questionnaires including questions on cough and phlegm. In chronic obstructive pulmonary disease (COPD) much controversy exists regarding the importance of mucus hypersecretion. From being the key element in the 'British...... hypothesis' it was reduced to being an innocent disorder in the 1980s but is now again recognized as a potential risk factor for an accelerated loss of lung function. Whereas early studies in mainly occupational cohorts showed no effect of chronic mucus hypersecretion on decline in lung function......, such an effect has been shown in subsequent studies on general population samples. Chronic mucus hypersecretion also increases risk of hospital admission which may be due to an increased risk of lower respiratory tract infection. In severe COPD this may explain the increased mortality associated...

  3. [Scientific journalism and epidemiological risk].

    Science.gov (United States)

    Luiz, Olinda do Carmo

    2007-01-01

    The importance of the communications media in the construction of symbols has been widely acknowledged. Many of the articles on health published in the daily newspapers mention medical studies, sourced from scientific publications focusing on new risks. The disclosure of risk studies in the mass media is also a topic for editorials and articles in scientific journals, focusing the problem of distortions and the appearance of contradictory news items. The purpose of this paper is to explore the meaning and content of disclosing scientific risk studies in large-circulation daily newspapers, analyzing news items published in Brazil and the scientific publications used as their sources during 2000. The "risk" is presented in the scientific research projects as a "black box" in the meaning of Latour, with the news items downplaying scientific disputes and underscoring associations between behavioral habits and the occurrence of diseases, emphasizing individual aspects of the epidemiological approach, to the detriment of the group.

  4. Epidemiology of acute wrist trauma

    DEFF Research Database (Denmark)

    Larsen, C F; Lauritsen, Jens

    1993-01-01

    Epidemiological data on wrist injuries in a population can be used for planning by applying them to criteria for care and thus deriving estimates of provisions for care according to currently desirable standards. In a 1-year study all patients > or = 15 years with acute wrist trauma and treated...... in the emergency room were examined according to an algorithm until a diagnosis was established. The overall incidence of wrist trauma was 69 per 10,000 inhabitants per year. Incidence of wrist trauma requiring x-ray examination was 58 per 10,000 per year. The incidence of distal radius fractures was 27 per 10...... using data from a population-based study. A completeness rate of 0.56 (95% confidence interval: 0.31-0.78) was found. An x-ray had been taken for all patients reporting a fracture thus justifying the use of fractures as an incidence measure when comparing groups of patients with wrist trauma....

  5. Epidemiology of Haemophilus ducreyi Infections.

    Science.gov (United States)

    González-Beiras, Camila; Marks, Michael; Chen, Cheng Y; Roberts, Sally; Mitjà, Oriol

    2016-01-01

    The global epidemiology of Haemophilus ducreyi infections is poorly documented because of difficulties in confirming microbiological diagnoses. We evaluated published data on the proportion of genital and nongenital skin ulcers caused by H. ducreyi before and after introduction of syndromic management for genital ulcer disease (GUD). Before 2000, the proportion of GUD caused by H. ducreyi ranged from 0.0% to 69.0% (35 studies in 25 countries). After 2000, the proportion ranged from 0.0% to 15.0% (14 studies in 13 countries). In contrast, H. ducreyi has been recently identified as a causative agent of skin ulcers in children in the tropical regions; proportions ranged from 9.0% to 60.0% (6 studies in 4 countries). We conclude that, although there has been a sustained reduction in the proportion of GUD caused by H. ducreyi, this bacterium is increasingly recognized as a major cause of nongenital cutaneous ulcers.

  6. Worldwide molecular epidemiology of HIV

    Directory of Open Access Journals (Sweden)

    Henry I Z Requejo

    2006-04-01

    Full Text Available Human immunodeficiency virus (HIV is the worldwide disseminated causative agent of acquired immunodeficiency syndrome (AIDS. HIV is a member of the Lentivirus genus of Retroviridae family and is grouped in two types named HIV-1 and HIV-2. These viruses have a notable ability to mutate and adapt to the new conditions of human environment. A large incidence of errors at the transcriptional level results in changes on the genetic bases during the reproductive cycle. The elevated genomic variability of HIV has carried important implications for the diagnosis, treatment and prevention as well as epidemiologic investigations. The present review describes important definitions and geographical distribution of subtypes, circulating recombinant forms and other genomic variations of HIV. The present study aimed at leading students of Biomedical Sciences and public health laboratory staff guidance to general and specific knowledge about the genomic variability of the HIV.

  7. EPIDEMIOLOGICAL EVALUATION OF COLORECTAL CANCER

    Directory of Open Access Journals (Sweden)

    B. Shafayan M. Keyhani

    2003-07-01

    Full Text Available This study was carried out to analyze certain epidemiological variations in Iranian patients with colorectal cancer. (CRC: From March 1981 up to March 1993, 103 patients were analyzed retrospectively for age, gender, marital state, job, nutritional habits, presenting symptoms and histopathological features. Most of the patients with colorectal cancer were male, age range 20-75 (mean 56, 25.4 percent were long-term smokers and bleeding was the most common symptom. The rectum was the most common site and moderately differentiated carcinoma was considered as the main common histopathological variety. In conclusion, increasing incidence of colorectal cancer in younger Iranian population, below 30 and late admission and diagnosis were the main findings in the present study necessitating screening programs with annual fecal occult blood tests in high risk families.

  8. On the epidemiology of influenza

    Directory of Open Access Journals (Sweden)

    Scragg Robert

    2008-02-01

    Full Text Available Abstract The epidemiology of influenza swarms with incongruities, incongruities exhaustively detailed by the late British epidemiologist, Edgar Hope-Simpson. He was the first to propose a parsimonious theory explaining why influenza is, as Gregg said, "seemingly unmindful of traditional infectious disease behavioral patterns." Recent discoveries indicate vitamin D upregulates the endogenous antibiotics of innate immunity and suggest that the incongruities explored by Hope-Simpson may be secondary to the epidemiology of vitamin D deficiency. We identify – and attempt to explain – nine influenza conundrums: (1 Why is influenza both seasonal and ubiquitous and where is the virus between epidemics? (2 Why are the epidemics so explosive? (3 Why do they end so abruptly? (4 What explains the frequent coincidental timing of epidemics in countries of similar latitude? (5 Why is the serial interval obscure? (6 Why is the secondary attack rate so low? (7 Why did epidemics in previous ages spread so rapidly, despite the lack of modern transport? (8 Why does experimental inoculation of seronegative humans fail to cause illness in all the volunteers? (9 Why has influenza mortality of the aged not declined as their vaccination rates increased? We review recent discoveries about vitamin D's effects on innate immunity, human studies attempting sick-to-well transmission, naturalistic reports of human transmission, studies of serial interval, secondary attack rates, and relevant animal studies. We hypothesize that two factors explain the nine conundrums: vitamin D's seasonal and population effects on innate immunity, and the presence of a subpopulation of "good infectors." If true, our revision of Edgar Hope-Simpson's theory has profound implications for the prevention of influenza.

  9. Global epidemiology of celiac disease

    Directory of Open Access Journals (Sweden)

    S. V. Bykova

    2018-01-01

    Full Text Available The review presents the data on the prevalence of celiac disease in various world regions. The numbers of patients with celiac disease continues to rise every year. According to some authors, this is to be related not only to improvement in diagnosis, but to other extrinsic factors, as well, that require additional studies. In the 1980s the prevalence of this disease was 1.05%, and by the beginning of 2000s, it amounted to 1.99%. In particular, from 1993 to 2002 in Britain its incidence increased from 6 to 13.3 per 100,000. Both raised awareness of doctors and conduction of epidemiological studies play a decisive role in the improvement of the diagnosis of celiac disease. The information cumulated up to now makes it possible to conclude that the highest diagnostic rates of celiac disease can be found in the risk groups. They include 1st and 2nd degree relatives of patients with celiac disease, patients with autoimmune disorders (type 1 diabetes mellitus, autoimmune thyroiditis; those with clinical signs of an intestinal disorder, such as chronic diarrhea, as well as patients with anemia, osteoporosis and high transaminase levels of unknown origin. According to the Finnish epidemiological study, the prevalence of celiac disease, depending on the risk group, may vary from 6.6 to 16.3%. The guidelines by the American College of Gastroenterology, British Society of Gastroenterology, North-American Society of Pediatric Gastroenterology, and the Russian Consensus on Diagnosis and Treatment of Celiac Disease in Adults and Children all recommend thorough examination of patients from the risk groups. Active diagnosis of celiac disease (screening has been recognized as one of the approaches to primary prevention to autoimmune disorders and cancer.

  10. VOGES-PROSKAUER AND COAGULASE TESTS TO THE LABORATORIAL DIAGNOSTIC OF Staphylococcus aureus INCLUDED IN THE EPIDEMIOLOGY OF BOVINE MASTITIS UTILIZAÇÃO DO TESTE DE VOGES-PROSKAUER E DA COAGULASE PARA O DIAGNÓSTICO LABORATORIAL DE Staphylococcus aureus ENVOLVIDOS NA EPIDEMIOLOGIA DA MASTITE BOVINA

    Directory of Open Access Journals (Sweden)

    Luiz Francisco Zafalon

    2009-12-01

    na prova de coagulase lenta com plasma de coelho e com distintos níveis de chuvas ocorridas na região da propriedade à qual os animais pertenciam. Os testes de VP e de coagulase foram realizados após o isolamento das amostras bacterianas em ágar sangue, visualização de lâminas após a realização da coloração de Gram e a verificação da produção de catalase. Todas as cepas isoladas foram confirmadas por meio da amplificação de fragmentos de DNA cromossômico específico de S. aureus. Identificou-se um total de 329 amostras como S. aureus, das quais 167 isoladas a partir do leite, 117 originaram-se de óstios e 45 de insufladores dos conjuntos de ordenha. Dentre as amostras isoladas, 85,0%, 71,1% e 69,2% de S. aureus que se originaram de leite, insufladores e óstios, respectivamente, apresentaram coagulação completa à prova de coagulase. Encontraram-se especificidades reduzidas para o teste de VP, para os diferentes graus de coagulação identificados, tanto no período com menos chuvas como no de maiores níveis pluviométricos. As sensibilidades diagnósticas identificadas para o teste de VP mostraram-se superiores em período com menor quantidade de chuvas para todas as fontes e graus de coagulação, exceto em amostras isoladas em óstios, que apresentaram coagulação incompleta, e em amostras oriundas de insufladores, que apresentaram coagulação completa. Recomenda-se o teste de VP como uma boa ferramenta diagnóstica para a identificação de S. aureus em conjunto com outros testes como o de coagulase, principalmente em amostras de leite oriundas de quartos mamários com mastite e em períodos com menor ocorrência de chuvas.


PALAVRAS-CHAVES: Bacteriologia, diagnóstico, leite, sanidade animal. 

  • Epidemiological assessment of canine brucellosis

    Directory of Open Access Journals (Sweden)

    Megid J.

    1999-01-01

    Full Text Available Observou-se brucelose canina em quatro canis diferentes. Os canis apresentaram animais com história de aborto, mortalidade em neonatos e nascimentos prematuros. A porcentagem de animais soropositivos para brucelose canina, pela prova de imunodifusão em ágar gel, variou de 4,6 a 57,1%. Observou-se correlação positiva entre porcentagem de animais positivos e aspectos reprodutivos e condições de aglomeração.

  • Epidemiological study around La Hague

    International Nuclear Information System (INIS)

    1999-01-01

    The North Cotentin is in France, the area where have been led until now, the biggest number of epidemiology studies on the effects of ionizing radiations on man, in order to assess the leukemia incidences and other cancer pathologies around nuclear facilities. The North Cotentin concentrates four nuclear installations.The objective of this file is to take stock of the situation in this field. In 1995 and 1998 have been published two sections of an epidemiology study about the incidence of leukemia in North Cotentin (J.F. Viel study for the period 1978-1992, Spira study for 1993-1997). The study of the Professor Spira does not bring to the fore a significant excess of leukemia for the period 1978-1997. The report of the professor Spira advocates several complementary epidemiology studies to precise or complete the data and lighten the causes of leukemia in North Cotentin. The studies of J.F.Viel shows that it does not exist a significant excess of cases in the studied area (25 cases for 22.8 expected cases, so a non significant difference) but notices an aggregate at the limit to be significant in the Beaumont-Hague canton (4 cases for 1.4 expected cases). J.F.Viel puts forward a relationship between the risk increase (of leukemia incidence) and some individual characteristics linked to the way of life of the studied persons: the North Cotentin beaches frequenting by the mothers or the children at least one time by month, the consumption of fish or shellfish having a local origin at least one time by week. This study suggests that it is the radioactivity, on the beaches on in fishes and shellfish that would be at the origin of the additional noticed leukemia. The authorities asked at the beginning of 1997, a scientific commission directed by the Professor Souleau to propose a new epidemiology study on the leukemia risk around La Hague. The report concludes that the leukemia incidence in the North Cotentin is in accordance with the expected incidence (25 observed

  • La enseñanza de estrategias metacognitivas para el mejoramiento de la comprensión lectora. Estado de la cuestión

    Directory of Open Access Journals (Sweden)

    Lucero Aragón Espinosa

    2009-01-01

    Full Text Available En este artículo se presenta una revisión de estudios sobre la enseñanza de estrategias metacognitivas para el mejoramiento de la comprensión lectora. Se analizaron reportes de investigación y ensayos teóricos publicados entre 1996 y 2008. Sus resultados fueron reseñados y organizados en una matriz que permitió categorizar las variables abordadas en los estudios. Los reportes de investigación revisados mostraron una mejora significativa de la comprensión lectora en los estudiantes, luego de la participación en los programas de instrucción ofrecidos. El balance plantea algunas directrices generales y específicas que podrían ser tenidas en cuenta por profesionales interesados en diseñar, implementar y evaluar programas de prevención e intervención dirigidos al mejoramiento de la comprensión lectora de los estudiantes, en contextos educativos formales.

  • An animated depiction of major depression epidemiology

    Directory of Open Access Journals (Sweden)

    Patten Scott B

    2007-06-01

    Full Text Available Abstract Background Epidemiologic estimates are now available for a variety of parameters related to major depression epidemiology (incidence, prevalence, etc.. These estimates are potentially useful for policy and planning purposes, but it is first necessary that they be synthesized into a coherent picture of the epidemiology of the condition. Several attempts to do so have been made using mathematical modeling procedures. However, this information is not easy to communicate to users of epidemiological data (clinicians, administrators, policy makers. Methods In this study, up-to-date data on major depression epidemiology were integrated using a discrete event simulation model. The mathematical model was animated in Virtual Reality Modeling Language (VRML to create a visual, rather than mathematical, depiction of the epidemiology. Results Consistent with existing literature, the model highlights potential advantages of population health strategies that emphasize access to effective long-term treatment. The paper contains a web-link to the animation. Conclusion Visual animation of epidemiological results may be an effective knowledge translation tool. In clinical practice, such animations could potentially assist with patient education and enhanced long-term compliance.

  • An animated depiction of major depression epidemiology.

    Science.gov (United States)

    Patten, Scott B

    2007-06-08

    Epidemiologic estimates are now available for a variety of parameters related to major depression epidemiology (incidence, prevalence, etc.). These estimates are potentially useful for policy and planning purposes, but it is first necessary that they be synthesized into a coherent picture of the epidemiology of the condition. Several attempts to do so have been made using mathematical modeling procedures. However, this information is not easy to communicate to users of epidemiological data (clinicians, administrators, policy makers). In this study, up-to-date data on major depression epidemiology were integrated using a discrete event simulation model. The mathematical model was animated in Virtual Reality Modeling Language (VRML) to create a visual, rather than mathematical, depiction of the epidemiology. Consistent with existing literature, the model highlights potential advantages of population health strategies that emphasize access to effective long-term treatment. The paper contains a web-link to the animation. Visual animation of epidemiological results may be an effective knowledge translation tool. In clinical practice, such animations could potentially assist with patient education and enhanced long-term compliance.

  • Epidemiological issues related to dose reconstruction

    International Nuclear Information System (INIS)

    Shore, R.E.

    1996-01-01

    When a dose reconstruction is performed around some nuclear site, a decision has to be made as to whether an epidemiologic study should be performed there and, if so, what form the study should take. The goal of this paper is to provide an overview of epidemiologic and biostatistical issues that help determine whether an epidemiologic study around a nuclear facility is worthwhile doing from a scientific standpoint. We are all aware that public health and sociopolitical concerns often assume considerable importance in these decisions, but they will not be considered here. 27 refs., 2 tabs

  • Radon epidemiology: A guide to the literature

    International Nuclear Information System (INIS)

    Marks, S.

    1988-12-01

    This document was written as a comprehensive overview of the voluminous literature on both uranium miner and residential radon epidemiology studies. This document provides the reader with a fairly complete list of radon epidemiology publications and key features of each, so that readers may further pursue only those publications of interest in the vast body of radon literature. A companion document, exploring all on-going residential radon epidemiology studies will be published by the Office of Health and Environmental Research (OHER), the Department of Energy (DOE) in the spring of 1989

  • Using epidemiological survey data to infer geographic distributions of leishmaniasis vector species Utilização dos dados de levantamentos epidemiológicos para inferir a distribuição geográfica de vetores da leishmaniose

    Directory of Open Access Journals (Sweden)

    A. Townsend Peterson

    2004-02-01

    Full Text Available An important aspect of tropical medicine is analysis of geographic aspects of risk of disease transmission, which for lack of detailed public health data must often be reduced to an understanding of the distributions of critical species such as vectors and reservoirs. We examine the applicability of a new technique, ecological niche modeling, to the challenge of understanding distributions of such species based on municipalities in the state of São Paulo in which a group of 5 Lutzomyia sandfly species have been recorded. The technique, when tested based on independent occurrence data, yielded highly significant predictions of species' distributions; minimum sample sizes for effective predictions were around 40 municipalities.Um aspecto importante da medicina tropical é a análise de aspectos geográficos relacionados com o risco de transmissão de doenças. Devido à ausência de dados detalhados de saúde pública, estas análises são freqüentemente reduzidas à compreensão da distribuição de espécies críticas como vetores e reservatórios. Neste trabalho, é examinada a aplicabilidade de uma nova técnica, a modelagem de nicho ecológico, no estudo da distribuição destas espécies nos municípios do Estado de São Paulo, onde um grupo de 5 mosquitos do gênero Lutzomyia foi encontrado. A técnica foi testada em conjuntos de dados independentes, resultando em previsões altamente significativas; a amostragem mínima para se obter previsões eficazes foi de cerca de 40 municípios.

  • Internal dosimetry for epidemiologic studies

    International Nuclear Information System (INIS)

    Groer, P.G.

    1987-01-01

    In traditional epidemiologic analyses, a single valued summary index, the standardized mortality ratio (SMR), is quite popular. The SMR is simply the ratio of the number of deaths observed in the study population to the number of deaths expected if the study population were subject to the age-specific rates of a standard population. SMRs for all causes or specific causes can be calculated. For such a simple analysis an exposed cohort is often characterized by an average organ or whole body dose or dose interval, and the necessary dose estimation effort is relatively minor. Modern statistical methods focus on the estimation of the cause-specific mortality rate λ for study populations exposed to ionizing radiations or toxic chemicals. The dependence of λ on factors other than demographic characteristics, such as race and sex, is usually described through a parametric model. Such factors, often called covariates or covariables, are incorporated in the mathematical expression for the hazard rate. The external gamma dose or the internal lung dose from inhaled uranium are good examples for covariates. This type of analysis permits the use of individual doses and gives a detailed and quantitative description of the mortality rate as a function of the covariables, but at the cost of a major dosimetric effort. The generation of the necessary dose information and also the calculational efforts become especially taxing for time-dependent covariates such as an internal, cumulative organ dose. 4 refs

  • The epidemiology of premature ejaculation.

    Science.gov (United States)

    Saitz, Theodore Robert; Serefoglu, Ege Can

    2016-08-01

    Vast advances have occurred over the past decade with regards to understanding the epidemiology, pathophysiology and management of premature ejaculation (PE); however, we still have much to learn about this common sexual problem. As a standardized evidence-based definition of PE has only recently been established, the reported prevalence rates of PE prior to this definition have been difficult to interpret. As a result, a large range of conflicting prevalence rates have been reported. In addition to the lack of a standardized definition and operational criteria, the method of recruitment for study participation and method of data collection have obviously contributed to the broad range of reported prevalence rates. The new criteria and classification of PE will allow for continued research into the diverse phenomenology, etiology and pathogenesis of the disease to be conducted. While the absolute pathophysiology and true prevalence of PE remains unclear, developing a better understanding of the true prevalence of the disease will allow for the completion of more accurate analysis and treatment of the disease.

    1. Epidemiology of Ciguatera in Florida.

      Science.gov (United States)

      Radke, Elizabeth G; Reich, Andrew; Morris, John Glenn

      2015-08-01

      Ciguatera is the most commonly reported marine food-borne illness worldwide. Because there is a biological plausibility that ciguatera may be impacted by long-term climate variability and Florida is on the northern border of the geographic distribution of ciguatera, it is important to update our understanding of its epidemiology in Florida. We performed an analysis of 291 reports in Florida from 2000 to 2011 and an e-mail survey of 5,352 recreational fishers to estimate incidence and underreporting and identify high risk demographic groups, fish types, and catch locations. Incidence was 5.6 per 100,000 adjusted for underreporting. Hispanics had the highest incidence rate (relative risk [RR] = 3.4) and were more likely to eat barracuda than non-Hispanics. The most common catch locations for ciguatera-causing fish were the Bahamas and Florida Keys. Cases caused by fish from northern Florida were infrequent. These results indicate that ciguatera incidence is higher than estimated from public health reports alone. There is little evidence that incidence or geographic range has increased because of increased seawater temperatures since earlier studies. © The American Society of Tropical Medicine and Hygiene.

    2. Foot burns: epidemiology and management.

      Science.gov (United States)

      Hemington-Gorse, S; Pellard, S; Wilson-Jones, N; Potokar, T

      2007-12-01

      This is a retrospective study of the epidemiology and management of isolated foot burns presenting to the Welsh Centre for Burns from January 1998 to December 2002. A total of 289 were treated of which 233 were included in this study. Approximately 40% were in the paediatric age group and the gender distribution varied dramatically for adults and children. In the adult group the male:female ratio was 3.5:1, however in the paediatric group the male:female ratio was more equal (1.6:1). Scald burns (65%) formed the largest group in children and scald (35%) and chemical burns (32%) in adults. Foot burns have a complication rate of 18% and prolonged hospital stay. Complications include hypertrophic scarring, graft loss/delayed healing and wound infection. Although isolated foot burns represent a small body surface area, over half require treatment as in patients to allow for initial aggressive conservative management of elevation and regular wound cleansing to avoid complications. This study suggests a protocol for the initial acute management of foot burns. This protocol states immediate referral of all foot burns to a burn centre, admission of these burns for 24-48 h for elevation, regular wound cleansing with change of dressings and prophylactic antibiotics.

    3. Epidemiology of sporotrichosis in Venezuela.

      Science.gov (United States)

      Mata-Essayag, Sofia; Delgado, Alejandro; Colella, Maria T; Landaeta-Nezer, Maria E; Rosello, Arantza; Perez de Salazar, Celina; Olaizola, Carolina; Hartung, Claudia; Magaldi, Sylvia; Velasquez, Etna

      2013-08-01

      Sporotrichosis is one of the most common subcutaneous mycoses in Venezuela. It is a granulomatous chronic infection with cutaneous or subcutaneous tissue lesions. Regional lymphatic involvement may be present; extracutaneous disease is rare. The causal fungus Sporothrix schenckii has been isolated from soil, vegetation, and animals on numerous occasions and in many localities throughout the world. The aim of this study is to describe clinical and epidemiological features of cases of sporotrichosis observed in Venezuela and review of the literature. We included the demographic data, clinical features, diagnostic methods, treatment, and follow-up of patients with sporotrichosis from 1963 to 2009, diagnosed at the Department of Medical Mycology. One-hundred and thirty-three sporotrichosis cases were diagnosed. Most patients were under the age of 30 years (66.15%). In 61.6% of them, the mode of transmission was not identified. The predominant clinical form in this population was lymphocutaneous (63.15%). Direct microscopic diagnosis was performed in 123 cases, and 57.9% yielded positive results for asteroid body. Sporotrichosis is an endemic subcutaneous mycosis in Venezuela. There are no reports to this date of disseminated forms of the disease, even amongst patients with acquired immunodeficiency syndrome. Direct microscopic examination of wet mount slides with saline solution or distilled water in the search for asteroid bodies is paramount. Saturated sodium and potassium iodine solutions continue to be extremely efficacious and affordable to most of our patients, therefore our treatment of choice. © 2013 The International Society of Dermatology.

    4. Epidemiology of cancer in children

      International Nuclear Information System (INIS)

      Greenberg, R.S.; Shuster, J.L. Jr.

      1985-01-01

      The epidemiologic features of cancers among children have stimulated abundant descriptive and analytic investigation. The descriptive work has demonstrated consistent differences in the incidence rates of these cancers by anatomic site, age, race, and gender. It is clear that the various forms of cancer during childhood have distinctive patterns of occurrence. To a large extent, the characteristic population distributions of these diseases may represent differences in the underlying etiologic processes. Analytic studies of cancer during childhood have addressed possible genetic and environmental risk factors for these diseases. The demonstration of cancers induced by transplacental exposure to diethylstilbestrol has confirmed the speculation that the prenatal environment may influence subsequent carcinogenesis. Although possible leukemogenic effects of intrauterine diagnostic irradiation remain controversial, the issue may become unimportant clinically as prenatal irradiation is replaced by other diagnostic modalities (194). To date, studies of prenatal ultrasound have provided no evidence of an overall excess of subsequent malignancies. Postnatal exposure to high doses of irradiation is known to produce considerable excesses of leukemias and other cancers. At present, there are insufficient data available to reach a firm conclusion on the possible carcinogenic effects of exposure during childhood to low doses of irradiation, fringe magnetic fields, or chemicals

    5. Epidemiology of radiogenic breast cancer

      International Nuclear Information System (INIS)

      Howe, G.R.

      1984-01-01

      The primary objective of epidemiologic studies of radiogenic breast cancer is to use empirical data from human populations exposed to radiation, in order to delineate increases in risk of breast cancer as a function of the radiation characteristics and the characteristics of the women exposed. In addition, such empirical data may be used to test hypotheses concerning the biological mechanism of radiation-induced breast cancer, and this mechanism in turn may serve as a useful model both for other radiogenic solid tumors, and for breast tumors induced by other carcinogens. Specifically, the objective may be formulated in terms of developing an appropriate relatively simple mathematical model, whose functional form may be tested and whose parameters may be estimated from the relevant human data. It is necessary to derive such a model, both because of the sampling instability of estimates based on small subgroups of populations and also because observations may not be available in populations with the characteristics of interest. These latter two restrictions are exemplified by the problem of estimating an increase in risk for individuals with relatively small exposures, and the problem of estimating lifetime risk

    6. TFOS DEWS II Epidemiology Report.

      Science.gov (United States)

      Stapleton, Fiona; Alves, Monica; Bunya, Vatinee Y; Jalbert, Isabelle; Lekhanont, Kaevalin; Malet, Florence; Na, Kyung-Sun; Schaumberg, Debra; Uchino, Miki; Vehof, Jelle; Viso, Eloy; Vitale, Susan; Jones, Lyndon

      2017-07-01

      The subcommittee reviewed the prevalence, incidence, risk factors, natural history, morbidity and questionnaires reported in epidemiological studies of dry eye disease (DED). A meta-analysis of published prevalence data estimated the impact of age and sex. Global mapping of prevalence was undertaken. The prevalence of DED ranged from 5 to 50%. The prevalence of signs was higher and more variable than symptoms. There were limited prevalence studies in youth and in populations south of the equator. The meta-analysis confirmed that prevalence increases with age, however signs showed a greater increase per decade than symptoms. Women have a higher prevalence of DED than men, although differences become significant only with age. Risk factors were categorized as modifiable/non-modifiable, and as consistent, probable or inconclusive. Asian ethnicity was a mostly consistent risk factor. The economic burden and impact of DED on vision, quality of life, work productivity, psychological and physical impact of pain, are considerable, particularly costs due to reduced work productivity. Questionnaires used to evaluate DED vary in their utility. Future research should establish the prevalence of disease of varying severity, the incidence in different populations and potential risk factors such as youth and digital device usage. Geospatial mapping might elucidate the impact of climate, environment and socioeconomic factors. Given the limited study of the natural history of treated and untreated DED, this remains an important area for future research. Copyright © 2017 Elsevier Inc. All rights reserved.

    7. Snowboard traumatology: an epidemiological study.

      Science.gov (United States)

      Pigozzi, F; Santori, N; Di Salvo, V; Parisi, A; Di-Luigi, L

      1997-06-01

      In the past 10 years, snowboarding has become a popular winter sport among young people, and the number of accidents has increased proportionately. The incidence of traumas from snowboarding is shown to be 4 to 6 for every 1000 medical examinations, which is similar to that of downhill skiing. However, other important statistical differences exist between the two sports. This study of 106 snowboarding-related injury cases analyzes the epidemiology of these injuries in Italy. Results found that 45.1% of injuries are located in the upper limbs and that significant advantages are obtained with the introduction of guards to protect the upper limbs during descent. Serious ligament injuries to the knee are more rare in snowboarding than in downhill skiing. In both sports, injuries are more common with rigid boots, which lead to a higher incidence of injury to the upper limbs. Finally, a high percentage of injury to beginners was found in this study. Training courses for those who are considering taking up the sport of snowboarding could significantly lower their risk of trauma.

    8. [Epidemiology of pain in Gabon].

      Science.gov (United States)

      Nzoghe Nguema, Pierre; Ngaka Nsafu, D

      2004-01-01

      The authors report on a prospective survey which took place from January 1999 to December 2000 - the epidemiology of pain in Gabon - to determine its distribution in the population. Ninety-eight women and eighty-four men aged 17 to 80 years old (mean age: 50) who consulted at the pain clinic were included in the study, a majority of the patients being aged between 21 and 60 years. Lower back pains and gonalgias secondary to osteo-arthritis or arthritis were more common in the North of the country, where the patients represented 57.7% of the sample, these two previous localisations along with cephalagias accounting for 52.7% of the motives for the visits. Thoracic and abdominal pains common in both men and women in the South were psychological. Patients working in the tertiary sector represented 45.3% of the patients, those of the secondary sector 24.4%, and those of the primary 20.3%. The non-steroidal anti-inflammatory analgesics (NSAI) associated with WHO grade 1 and 2 analgesics were effective in 50% of cases, some of whom also needed steroidal articular infiltration. Psychological pains were soothed by amitriptyline. A specific training of doctors and paramedics in pain treatment is necessary to improve care and assistance in this area. Copyright John Libbey Eurotext 2003.

    9. Epidemiological features of brain tumors

      Directory of Open Access Journals (Sweden)

      Živković Nenad

      2013-01-01

      Full Text Available Brain tumors account for 1.4% of all cancers and 2.4% of all cancer-related deaths. The incidence of brain tumors varies and it is higher in developed countries of Western Europe, North America, Australia and New Zealand. In Serbia, according to data from 2009, malignant brain tumors account for 2. 2 of all tumors, and from all cancer­related deaths, 3.2% is caused by malignant brain tumors. According to recent statistical reports, an overall incidence of brain tumors for benign and malignant tumors combined is 18.71 per 100,000 persons/year. The most common benign brain tumor in adults is meningioma, which is most present in women, and the most common malignant tumor is glioblastoma, which is most present in adult men. Due to high mortality, especially in patients diagnosed with glioblastoma and significant brain tumor morbidity, there is a constant interest in understanding its etiology in order to possibly prevent tumor occurrence in future and enable more efficient treatment strategies for this fatal brain disease. Despite the continuously growing number of epidemiological studies on possible factors of tumor incidence, the etiology remains unclear. The only established environmental risk factor of gliomas is ionizing radiation exposure. Exposure to radiofrequency electromagnetic fields via cell phone use has gained a lot of attention as a potential risk factor of brain tumor development. However, studies have been inconsistent and inconclusive, so more definite results are still expected.

    10. Le domaine des co-infections et des maladies concomitantes du Réseau canadien pour les essais VIH des IRSC : lignes directrices canadiennes pour la prise en charge et le traitement de la co-infection par le VIH et l’hépatite C chez les adultes

      Science.gov (United States)

      Hull, Mark; Giguère, Pierre; Klein, Marina; Shafran, Stephen; Tseng, Alice; Côté, Pierre; Poliquin, Marc; Cooper, Curtis

      2014-01-01

      HISTORIQUE : De 20 % à 30 % des Canadiens qui vivent avec le VIH sont co-infectés par le virus de l’hépatite C (VHC), lequel est responsable d’une morbidité et d’une mortalité importantes. La prise en charge du VIH et du VHC est plus complexe en raison de l’évolution accélérée de la maladie hépatique, du choix et des critères d’initiation de la thérapie antirétrovirale et du traitement anti-VHC, de la prise en charge de la santé mentale et des toxicomanies, des obstacles socioéconomiques et des interactions entre les nouvelles thérapies antivirales à action directe du VHC et les antirétroviraux OBJECTIF : Élaborer des normes nationales de prise en charge des adultes co-infectés par le VHC et le VIH dans le contexte canadien. MÉTHODOLOGIE : Le Réseau canadien pour les essais VIH des Instituts de recherche en santé du Canada a réuni un groupe d’experts possédant des compétences cliniques en co-infection par le VIH et le VHC pour réviser les publications à jour ainsi que les lignes directrices et les protocoles en place. Après une vaste sollicitation afin d’obtenir des points de vue, le groupe de travail a approuvé des recommandations consensuelles, qu’il a caractérisées au moyen d’une échelle de qualité des preuves fondée sur la classe (bienfaits par rapport aux préjudices) et sur la catégorie (degré de certitude). RÉSULTATS : Toutes les personnes co-infectées par le VIH et le VHC devraient subir une évaluation en vue de recevoir un traitement du VHC. Les personnes qui ne sont pas en mesure d’entreprendre un traitement du VHC devraient être soignées pour le VIH afin de ralentir l’évolution de la maladie hépatique. La norme de traitement du VHC de génotype 1 est un régime comprenant de l’interféron pégylé et de la ribavirine dosée en fonction du poids, associés à un inhibiteur de la protéase du VHC. Pour les génotypes 2 ou 3, une bithérapie classique est recommandée pendant 24 semaines s

    11. Epidemiología del tabaquismo en México Epidemiology of tobacco use in Mexico

      Directory of Open Access Journals (Sweden)

      Pablo Antonio Kuri-Morales

      2006-01-01

      Full Text Available El consumo de tabaco es un problema de salud pública mundial. De acuerdo con la Organización Mundial de la Salud, el tabaquismo es la segunda causa principal de muerte en el mundo, con casi cinco millones de defunciones anuales. Se requiere contar con información y análisis sobre el consumo de tabaco para tener éxito en la lucha contra el tabaquismo y así orientar de mejor manera las medidas de prevención y control. En este artículo de revisión, realizado en México en 2006, se presenta un análisis comparativo de la información de la prevalencia del tabaquismo de la Encuesta Nacional de Adicciones 2002, en relación con los resultados obtenidos en encuestas anteriores. También se presenta la información de los fumadores jóvenes y los pasivos, el consumo de tabaco en la profesión médica y el efecto sobre la mortalidad, así como aspectos relevantes de análisis de esta epidemia. Tal información epidemiológica se observa en el contexto del componente tabaquismo del Plan de Acción de Tabaquismo y el Convenio Marco para el Control del Tabaco.Tobacco use is a worldwide public health problem. According to the World Health Organization (WHO, smoking is the second principal cause of death in the world, with almost five million deaths annually. Information about tobacco consumption is essential in order to improve the focus of prevention and control measures and thereby succeed in the struggle against tobacco use. This literature review, carried out in Mexico in 2006, presents a comparative analysis of information about smoking prevalence from the National Addictions Survey 2002, as it relates to results obtained in previous surveys. This review also presents information about youth and passive smoking, tobacco consumption in the medical profession and impact on mortality as aspects relevant to the analysis of this epidemic. Epidemiological information is viewed in the context of the tobacco use component of the Plan of Action on

    12. Oro para Colombia

      OpenAIRE

      Rubio Forero, María Claudia

      2016-01-01

      Las mujeres han debido atravesar un largo camino partiendo de la discriminación hasta empezar un proceso de equidad en la sociedad y en el deporte, de esta manera llegar a ser parte de un evento como los Juegos Olímpicos. Esta tesis toma el caso de tres atletas colombianas y describe su proceso de formación para lograr dos medallas de oro para el país.

    13. Estrategias para negociaciones exitosas.

      Directory of Open Access Journals (Sweden)

      José B. Parra V

      2010-01-01

      Full Text Available Las estrategias de negociación son herramientas para disminuir conflictos o para intercambiar bienes y servicios. Una negociación exitosa crea relaciones de solidaridad y propicia reciprocidad, cooperación y confianza para quienes tendrán relaciones permanentes de negociación con beneficios para ambas partes. Una estrategia de negociación exitosa requiere manejar el desarrollo del ambiente social del grupo de personas, con la finalidad de tener presente las fronteras que no pueden irrumpirse. Otro aspecto importante, es el lenguaje corporal utilizado por las personas y las tácticas que se practican. El manejo de esta información permite diseñar diferentes modelos de negociaciones para cada caso específico. Este documento propone la utilización de la herramienta MONACO, diseñada por los autores, que es un software útil para encontrar los mejores tácticas posibles dentro de una negociación; basándose en el lenguaje corporal que muestra el negociante oponente durante cada oferta monetaria. El uso de este software da al negociador la oportunidad de manejar las negociaciones con mayor control, el negociador que usa el software puede elegir una estrategia de acuerdo a las relaciones que espera mantener con el negociador oponente.

    14. Resolución de problemas científicos desde la historia de la ciencia: retos y desafíos para promover competencias cognitivo lingüísticas en la química escolar History of Science in the resolution of scientific problems: contributions to promote linguistic cognitive strengths for school Chemistry

      Directory of Open Access Journals (Sweden)

      Johanna Patricia Camacho González

      2008-01-01

      Full Text Available En este artículo proponemos abordar el enfrentamiento a la resolución de problemas en la química escolar por parte de los y las estudiantes asumiendo situaciones a las que se han enfrentado los científicos y las científicas en determinados y contextualizados momentos de la Historia de la Ciencia. Para ello, argumentamos algunos aspectos desde la literatura especializada en Didáctica de las Ciencias, que permiten sustentar esta propuesta. A continuación, describimos un episodio histórico sobre la discusión del S. XVIII entre Lavoisier y Priestley respecto a la descomposición del aire para ser utilizada como estrategia que promueva el desarrollo de las competencias cognitivolingüísticas. Finalmente, planteamos algunas directrices para orientar al profesorado de química en el logro de estos propósitos.The objective of this article is to approach the resolution of problems in the construction of knowledge in school science. In first place, show some aspects from specialized Literature. Later, we describe a historical episode of the discussion of Lavoisier and Priestley in S.XVIII about the combustion of the air. This is to be used as a strategy that promotes linguistic cognitive strengths. Finally, we propose some methodological directives to orient professors of chemistry to profit from these findings.

    15. EPIDEMIOLOGY OF CHOLERA OUTBREAK IN KAMPALA ...

      African Journals Online (AJOL)

      hi-tech

      77 No. 7 July 2000. EPIDEMIOLOGY OF CHOLERA OUTBREAK IN KAMPALA, UGANDA ... spread much (106 cases in 1995), resulting in a low level of immunity ... An intensive social ... development of a network of community health workers,.

    16. Salmonella epidemiology: A whirlwind of change.

      Science.gov (United States)

      Besser, John M

      2018-05-01

      The field of infectious disease epidemiology for Salmonella and other enteric pathogens is undergoing some of the most profound changes since the time of Kauffman and White. Rapid advances in "big data" technologies such as genomics and metagenomics are making it possible to monitor and control salmonellosis in new and exciting ways. Epidemiological methods are becoming increasingly robust through the routine use of standardized hypothesis-generating questionnaires, iterative open-ended interviewing, informational trace-backs and new modeling techniques for describing the attribution of disease to food sources. In addition, Salmonella epidemiology is facing important challenges and new opportunities due to the rapid adoption of culture independent diagnostic test panels by clinical laboratories. Where is this unprecedented wave of change taking us? This chapter will examine emerging trends in Salmonella epidemiology, and take a peek into the not-so-distant future. Published by Elsevier Ltd.

    17. Demographic and epidemiological characteristics of HIV ...

      African Journals Online (AJOL)

      Department of Epidemiology and Medical Statistics, College of Medicine, University of Ibadan, Ibadan, Nigeria ... Methods: Analysis of data extracted from electronic records of 17, 312 .... system for the purpose of privacy and confidentiality of.

    18. Anticholinesterase pesticides: metabolism, neurotoxicity, and epidemiology

      National Research Council Canada - National Science Library

      Satoh, Tetsuo, Ph. D; Gupta, Ramesh C

      2010-01-01

      .... The early portion of the book deals with metabolism, mechanisms and biomonitoring of anticholinesterase pesticides, while the later part deals with epidemiological studies, regulatory issues, and therapeutic intervention"--Provided by publisher.

    19. Epidemiology of small intestinal atresia in Europe

      DEFF Research Database (Denmark)

      Best, Kate E; Tennant, Peter W G; Addor, Marie-Claude

      2012-01-01

      The epidemiology of congenital small intestinal atresia (SIA) has not been well studied. This study describes the presence of additional anomalies, pregnancy outcomes, total prevalence and association with maternal age in SIA cases in Europe....

    20. Epidemiology in the Era of Big Data

      Science.gov (United States)

      Mooney, Stephen J; Westreich, Daniel J; El-Sayed, Abdulrahman M

      2015-01-01

      Big Data has increasingly been promoted as a revolutionary development in the future of science, including epidemiology. However, the definition and implications of Big Data for epidemiology remain unclear. We here provide a working definition of Big Data predicated on the so-called ‘3 Vs’: variety, volume, and velocity. From this definition, we argue that Big Data has evolutionary and revolutionary implications for identifying and intervening on the determinants of population health. We suggest that as more sources of diverse data become publicly available, the ability to combine and refine these data to yield valid answers to epidemiologic questions will be invaluable. We conclude that, while epidemiology as practiced today will continue to be practiced in the Big Data future, a component of our field’s future value lies in integrating subject matter knowledge with increased technical savvy. Our training programs and our visions for future public health interventions should reflect this future. PMID:25756221

    1. Anticholinesterase pesticides: metabolism, neurotoxicity, and epidemiology

      National Research Council Canada - National Science Library

      Satoh, Tetsuo, Ph. D; Gupta, Ramesh C

      2010-01-01

      ...; and epidemiology of poisonings and fatalities in people from short- and long- term exposures to these pesticides in different occupational settings on a individual country basis as well as on a global basis...

    2. Aplicação da metodologia de relacionamento probabilístico de base de dados para a identificação de óbitos em estudos epidemiológicos The use of a probabilistic record linkage methodology in databases to identify death records in epidemiological studies

      Directory of Open Access Journals (Sweden)

      Juliana Pires Machado

      2008-03-01

      Full Text Available A crescente disponibilidade de dados de abrangência nacional, organizados em distintos sistemas de informação, requer o desenvolvimento de metodologias para o relacionamento de variáveis constantes em diferentes bases de dados. Este artigo descreve e analisa a metodologia utilizada no relacionamento das bases de dados nacionais do Sistema de Informação de Beneficiários (planos privados de assistência à saúde e do Sistema de Informação de Mortalidade. Foram analisados os registros de óbitos e os registros de beneficiários no ano de 2004, identificando-se 92.566 óbitos em beneficiários de planos privados de saúde. O rigor na especificidade, em detrimento da sensibilidade do método empregado, não gerou vieses de seleção que pudessem comprometer as análises resultantes. A razão de mortalidade padronizada aponta a subestimação do número de óbitos, além de evidenciar diferenças no risco de morte entre as populações analisadas; no entanto, as diferentes situações de vida e saúde a que estão expostas podem ter interferido nos resultados.The increasing availability of nationwide data organized in distinct information systems requires the development of linkage methodologies to identify the relationships between the same variables in different databases. This article describes and analyzes the linkage methodology between two countrywide databases: the Brazilian Mortality System and the database of the population covered by private health insurance. Death registrations and the records of individuals covered by private health insurance in 2004 were analyzed. 92,566 deaths were identified in those covered by private health insurance. The strictness in specificity instead of sensitivity in the method employed did not lead to selection biases that could have compromised the resulting analyses. The standardized mortality ratio (SMR indicates underestimation of the number of deaths, in addition to showing differences in the

    3. How to make epidemiological training infectious.

      Directory of Open Access Journals (Sweden)

      Steve E Bellan

      Full Text Available Modern infectious disease epidemiology builds on two independently developed fields: classical epidemiology and dynamical epidemiology. Over the past decade, integration of the two fields has increased in research practice, but training options within the fields remain distinct with few opportunities for integration in the classroom. The annual Clinic on the Meaningful Modeling of Epidemiological Data (MMED at the African Institute for Mathematical Sciences has begun to address this gap. MMED offers participants exposure to a broad range of concepts and techniques from both epidemiological traditions. During MMED 2010 we developed a pedagogical approach that bridges the traditional distinction between classical and dynamical epidemiology and can be used at multiple educational levels, from high school to graduate level courses. The approach is hands-on, consisting of a real-time simulation of a stochastic outbreak in course participants, including realistic data reporting, followed by a variety of mathematical and statistical analyses, stemming from both epidemiological traditions. During the exercise, dynamical epidemiologists developed empirical skills such as study design and learned concepts of bias while classical epidemiologists were trained in systems thinking and began to understand epidemics as dynamic nonlinear processes. We believe this type of integrated educational tool will prove extremely valuable in the training of future infectious disease epidemiologists. We also believe that such interdisciplinary training will be critical for local capacity building in analytical epidemiology as Africa continues to produce new cohorts of well-trained mathematicians, statisticians, and scientists. And because the lessons draw on skills and concepts from many fields in biology--from pathogen biology, evolutionary dynamics of host--pathogen interactions, and the ecology of infectious disease to bioinformatics, computational biology, and

    4. Epidemiologic methods in mastitis treatment and control.

      Science.gov (United States)

      Thurmond, M C

      1993-11-01

      Methods and concepts of epidemiology offer means whereby udder health can be monitored and evaluated. Prerequisite to a sound epidemiologic approach is development of measures of mastitis that minimize biases and that account for sensitivity and specificity of diagnostic tests. Mastitis surveillance offers an ongoing and passive system for evaluation of udder health, whereas clinical and observational trials offer a more proactive and developmental approach to improving udder health.

    5. Cultural epidemiology: An introduction and overview

      OpenAIRE

      Weiss, Mitchell Gralnick

      2001-01-01

      Although the value of interdisciplinary collaboration between epidemiology and anthropology is both widely acknowledged and hotly contested, effective international health policy and multicultural health programmes require it. The EMIC framework for cultural studies of illness was developed in response to such needs, and a cultural epidemiology emerged from that framework as an interdisciplinary field of research on locally valid representations of illness and their distributions in cultural ...

    6. Issues in epidemiological studies of radiofrequency workers

      International Nuclear Information System (INIS)

      Hocking, B.

      1985-01-01

      The paper reviews some of the issues in a proposed epidemiological study of radiofrequency workers. First a few other epidemiological studies are discussed to illustrate some of the common problems such as inadequate definition of effects and/or exposure. Then technical problems in determining dosage and responses as well as study design are reviewed, and finally the administrative aspects of ethics, industrial relations and costs are considered

    7. Epidemiological Study of Heart Failure in China

      Directory of Open Access Journals (Sweden)

      Yang Guo

      2015-10-01

      Full Text Available Heart failure (HF is a complex clinical syndrome that results from any structural or functional impairment of ventricular filling or ejection of blood. HF is one of the most important and severe end stages of many cardiovascular diseases. Epidemiological studies of HF have focused mainly on the prevalence, incidence, mortality, fatality, and distribution and temporal trends of these indicators among different populations. This review highlights important epidemiological studies of HF in China.

    8. El papel de la epidemiología en la investigación de los trastornos mentales The role of epidemiology in mental disorder research

      Directory of Open Access Journals (Sweden)

      Guilherme Borges

      2004-10-01

      Full Text Available Los trastornos mentales, incluyendo los trastornos del uso de sustancias, hacen ya parte del panorama epidemiológico de México y seguirán en el escenario nacional por las próximas décadas, incrementando incluso su presencia como causa de enfermedad, discapacidad y muerte en nuestro país. Por lo tanto, el manejo epidemiológico de estos problemas se hace urgente. Este trabajo busca plantear el campo de estudio de la epidemiología de los trastornos mentales y sus limitaciones, haciendo énfasis en los elementos comunes de ésta con otras áreas más tradicionales de la epidemiología y en las aportaciones particulares de este campo epidemiológico a la psiquiatría en general y a la epidemiología en particular. Planteamos a continuación los diseños y problemas más comunes en este campo de la epidemiología, su utilidad para acciones de prevención, y señalamos los retos que nos esperan en el futuro. Una característica distintiva de esta área es que los trastornos mentales se manifiestan en dos niveles, como conducta (por ejemplo, una conducta compulsiva de lavarse las manos y como elemento de la vida mental del sujeto (por ejemplo, el pensamiento obsesivo sobre las bacterias que se encuentran presentes en todos lados y que son una fuente constante de amenaza para algunos sujetos. Debido a esto, mucho de lo que sabemos sobre estos fenómenos proviene del autorreporte que el sujeto es capaz de hacer sobre sus sentimientos (introspección, ya sea en una conversación con un clínico entrenado o expresándolos al endosar reactivos en un cuestionario estandarizado. Otro aspecto importante a resaltar es la necesidad de hablar en plural al referirnos a los trastornos mentales. Este campo de la epidemiología presenta también un carácter particular, bifacético: por un lado, este es un problema en sí mismo, que produce sufrimiento y motiva la búsqueda de atención especializada, con manifestaciones clínicas particulares. Por otro lado

    9. Epidemiology of blindness in children.

      Science.gov (United States)

      Solebo, Ameenat Lola; Teoh, Lucinda; Rahi, Jugnoo

      2017-09-01

      An estimated 14 million of the world's children are blind. A blind child is more likely to live in socioeconomic deprivation, to be more frequently hospitalised during childhood and to die in childhood than a child not living with blindness. This update of a previous review on childhood visual impairment focuses on emerging therapies for children with severe visual disability (severe visual impairment and blindness or SVI/BL).For children in higher income countries, cerebral visual impairment and optic nerve anomalies remain the most common causes of SVI/BL, while retinopathy of prematurity (ROP) and cataract are now the most common avoidable causes. The constellation of causes of childhood blindness in lower income settings is shifting from infective and nutritional corneal opacities and congenital anomalies to more resemble the patterns seen in higher income settings. Improvements in maternal and neonatal health and investment in and maintenance of national ophthalmic care infrastructure are the key to reducing the burden of avoidable blindness. New therapeutic targets are emerging for childhood visual disorders, although the safety and efficacy of novel therapies for diseases such as ROP or retinal dystrophies are not yet clear. Population-based epidemiological research, particularly on cerebral visual impairment and optic nerve hypoplasia, is needed in order to improve understanding of risk factors and to inform and support the development of novel therapies for disorders currently considered 'untreatable'. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

    10. Cannabis Epidemiology: A Selective Review.

      Science.gov (United States)

      Anthony, James C; Lopez-Quintero, Catalina; Alshaarawy, Omayma

      2017-01-04

      Globally, the most widely used set of compounds among the internationally regulated drugs is cannabis. To review evidence from epidemiological research on cannabis, organized in relation to this field's five main rubrics: quantity, location, causes, mechanisms, and prevention/ control. The review covers a selection of evidence from standardized population surveys, official statistics, and governmental reports, as well as published articles and books identified via MEDLINE, Web of Science, and Google Scholar as of July 2016. In relation to quantity, an estimated 3% to 5% of the world population is thought to have tried a cannabis product, with at least one fairly recent use, mainly extra-medical and outside boundaries of prescribed use. Among cannabis users in the United States, roughly one in 7-8 has engaged in medical marijuana use. In relation to location, prevalence proportions reveal important variations across countries and between subgroups within countries. Regarding causes and mechanisms of starting to use cannabis, there is no compelling integrative and replicable conceptual model or theoretical formulation. Most studies of mechanisms have focused upon a 'gateway sequence' and person-to-person diffusion, with some recent work on disability-adjusted life years. A brief review of cannabis use consequences, as well as prevention and control strategies is also provided. At present, we know much about the frequency and occurrence of cannabis use, with too little replicable definitive evidence with respect to the other main rubrics. Given a changing regulatory environment for cannabis products, new institutions such as an independent International Cannabis Products Safety Commission may be required to produce evidence required to weigh benefits versus costs. It is not clear that governmentsponsored research will be sufficient to meet consumer demand for balanced points of view and truly definitive evidence. Copyright© Bentham Science Publishers; For any queries

    11. Cannabis Epidemiology: A Selective Review

      Science.gov (United States)

      Anthony, James C.; Lopez-Quintero, Catalina; Alshaarawy, Omayma

      2017-01-01

      Background Globally, the most widely used set of compounds among the internationally regulated drugs is cannabis. Objective To review evidence from epidemiological research on cannabis, organized in relation to this field’s five main rubrics: quantity, location, causes, mechanisms, and prevention/control. Method The review covers a selection of evidence from standardized population surveys, official statistics, and governmental reports, as well as published articles and books identified via MEDLINE, Web of Science, and Google Scholar as of July 2016. Results In relation to quantity, an estimated 3% to 5% of the world population is thought to have tried a cannabis product, with at least one fairly recent use, mainly extra-medical and outside boundaries of prescribed use. Among cannabis users in the United States, roughly one in 7–8 has engaged in medical marijuana use. In relation to location, prevalence proportions reveal important variations across countries and between subgroups within countries. Regarding causes and mechanisms of starting to use cannabis, there is no compelling integrative and replicable conceptual model or theoretical formulation. Most studies of mechanisms have focused upon a ‘gateway sequence’ and person-to-person diffusion, with some recent work on disability-adjusted life years. A brief review of cannabis use consequences, as well as prevention and control strategies is also provided. Conclusion At present, we know much about the frequency and occurrence of cannabis use, with too little replicable definitive evidence with respect to the other main rubrics. Given a changing regulatory environment for cannabis products, new institutions such as an independent International Cannabis Products Safety Commission may be required to produce evidence required to weigh benefits versus costs. It is not clear that government sponsored research will be sufficient to meet consumer demand for balanced points of view and truly definitive evidence

    12. Epidemiological profile of infectious keratitis

      Directory of Open Access Journals (Sweden)

      Roberta Farias

      Full Text Available Abstract Objective: To evaluate the epidemiologic aspects of cornea ulcers in a referred ophthalmology private practice center. Methods: Retrospective study over electronic files of patients treated for corneal ulcers during a period of 7 years by the same physician (RJMF at Centro de Olhos São Francisco, between june 2007 and june 2014. These patients were evaluated for risk factors such as: trauma causes, co-morbidities and contact lenses use. They were also evaluated by the microorganism found at the smears, treatment and patient's outcome. Patients that didn't return with the smears results or that didn´t have a complete follow-up were excluded from the study. Results: A total of 242 patients were fully treated during this period. 55 patients were excluded and 187 patients were included. 28.88% (54/187 were positive for gram negative bacteria, 27.81% (52/187 for filamentous fungi, 16.04% (29/187 for gram positive bacteria and only 1.07% for acanthamoeba. Twenty-four patients had negative cultures and 21 patients had combined infections (bacteria + fungi or other combination. Corneal collagen Cross-linking was effective on melting arrest in 16 of the 16 patients that we have submitted to this procedure during 2008 and 2009. Among all the patients that had corneal infection and were previously using contact lenses, 81% were infected by pseudomonas or pseudomonas associated with other gram negative bacteria. Filamentous fungi had a strong association with physical trauma. While use of saline solution for contact lenses cleaning had a strong association with gram negative bacteria and biological trauma, a strong association with combined infection. Conclusion: Gram negative bacteria (Pseudomonas followed by filamentous fungi (Fusarium sp were the most frequent etiologic agent found in our study. Cross-link was effective on corneal melting arrest. Pseudomonas aeruginosa was the most frequent isolated agent on hydrophilic contact lenses wearers.

    13. Epidemiology and costs of diabetes.

      Science.gov (United States)

      Bruno, G; Landi, A

      2011-01-01

      The prevalence of diabetes is increasing worldwide, particularly in developing countries. In the next decades, India and China are expected to provide the greatest numbers of affected people, mainly owing to the increasing incidence of this disease in those countries. Regarding developed countries, such as in Europe and the United States, the increasing trend is mainly due to the prolonged survival of both the general and the diabetic populations. From an epidemiologic point of view, the first relevant point is that almost 80% of diabetes cases could be prevented just by avoiding overweight and obesity. The estimated attributable risk of excess body weight is extremely high; no other modifiable effect has such an impact on the health of the general population. The second relevant point is that the global trend of the disease shows a tendency to onset at a younger age. The third point is that in developed countries the prevalence of diabetes is increasing mainly among the elderly, who are responsible for the highest consumption of health care resources in absolute terms. Regarding type 1 diabetes, which represents one-tenth of affected individuals, both large geographic and temporal variations in disease incidence have been found, supporting the hypothesis of as yet unknown environmental determinants. The incidence is increasing in linear fashion, not supporting the hypothesis of younger age at onset as the main explanation for this trend. Because the prevalences of both type 1 and type 2 diabetes are increasing worldwide, they will produce a profound impact on overall health care costs. Copyright © 2011 Elsevier Inc. All rights reserved.

    14. Epidemiology of acromegaly in Ecuador.

      Science.gov (United States)

      López Gavilanez, Enrique; Guerrero Franco, Kempis; Solórzano Zambrano, Narcisa; Navarro Chávez, Manuel; López Estrella, Camilo; Vaca Burbano, Luis; Marriott Díaz, Eduardo

      2016-01-01

      To assess the epidemiology of acromegaly in the city of Guayaquil, Ecuador, and to compare our results to those reported in the literature. An analysis was made of retrospective and prospective data from all patients with acromegaly attending endocrinology clinics at the 4 main hospitals of the public health network of Guayaquil from January 2000 to December 2014. Age at diagnosis, estimated delay in diagnosis, imaging studies of pituitary gland, basal growth hormone (GH) level, GH after an oral glucose tolerance test (OGTT-GH), and serum levels of insulin-like growth factor 1 (IGF-1) were recorded. Incidence and prevalence of the disease were estimated using information from the 2010 census of population and housing. Forty-eight cases were recorded in the study period in 17 males (35.4%) and 31 females (64.5%); M/F ratio=1.8:1. Mean age at diagnosis was 47.3±16.8 years (range 18-86). Delay in diagnosis was 7.3±6.3 years (range 1-30). Mean age at diagnosis was 47.9±18.2 years in males and 46.3±15.8 years in females. Delay in diagnosis was 10.2±7.9 and 5.7±3.9 years in males and females, respectively. Prevalence of acromegaly is 18.7 cases per million inhabitants, and incidence of acromegaly 1.3 cases per million people per year. Acromegaly predominates in females, and is diagnosed in the fourth decade with a delay of approximately 8 years, usually even longer in males. Incidence and prevalence are lower than reported in international series. The disease is underdiagnosed and underreported in Ecuador. Copyright © 2016 SEEN. Publicado por Elsevier España, S.L.U. All rights reserved.

    15. A epidemiologia, os valores e o significado de paradigma Epidemiology, values, and the meaning of paradigm

      Directory of Open Access Journals (Sweden)

      Djalma Agripino de Melo Filho

      1997-10-01

      Full Text Available Recentemente, o emprego do termo paradigma chegou ao âmbito epidemiológico. Este texto analisou criticamente uma classificação de 'paradigmas epidemiológicos', proposta por Almeida-Filho. Inicialmente constatou-se que os valores não foram considerados como elementos fundamentais para a construção dos paradigmas, distanciando-se, assim, da matriz kuhniana. Uma vez que a sistematização procurou unir tendências antitéticas, ela pareceu estar mais próxima da epistéme foucaultiana. Finalmente, considerou-se mais apropriada a utilização do termo hegemonia, em vez de paradigma, para sistematizar períodos epidemiológicos, pois os valores das vertentes estão comprometidos com a particularidade (principalmente classe social.Use of the term paradigm has recently reached the epidemiological milieu. This article provides a critical analysis of a classification of "epidemiological paradigms" as proposed by Almeida-Filho. It was initially ascertained that values were not considered fundamental elements for the construction of paradigms, and that they therefore distanced themselves from the Kuhnian matrix. Systematization sought to unite antithetical tendencies and thus seemed closer to the Foucaltian epistéme. Finally, hegemony was considered a more appropriate term than paradigm for systematizing epidemiological periods, since the values of the different watersheds are committed to particularity (principally social class.

    16. 16 CFR 1000.26 - Directorate for Epidemiology.

      Science.gov (United States)

      2010-01-01

      ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Directorate for Epidemiology. 1000.26... AND FUNCTIONS § 1000.26 Directorate for Epidemiology. The Directorate for Epidemiology, managed by the Associate Executive Director for Epidemiology, is responsible for the collection and analysis of data on...

    17. Considerações acerca dos fundamentos teóricos da explicação em epidemiología Considerations concerning the theoretical foundations of explanation in epidemiology

      Directory of Open Access Journals (Sweden)

      Luiz Jacintho da Silva

      1985-08-01

      Full Text Available São analisadas as condições históricas do surgimento da epidemiologia como disciplina científica, em meados do século passado. É revista a evolução das bases teóricas do processo explicativo em epidemiologia até o momento atual. Especial atenção é dada ao papel da lógica positivista de Stuart Mill como base teórica da Epidemiologia até recentemente. São discutidas as alternativas teóricas correntes e proposta maior abertura da epidemiologia a diferentes correntes filosóficas como o caminho para o estabelecimento da epidemiologia como uma ciência madura.The historical conditions surrounding the emergence, by the mid-19th century, of epidemiology as a scientific discipline, were analysed. Special consideration is given to the influence of the political milieu of Victorian England in the definition of the theoretical basis of epidemiology. The English Sanitary Movement is seen as a response of the emerging bourgeoise to problems created by industrialization and urbanization. As a consequence, epidemiology was strongly influenced by Stuart Mill's system of logic. During the latter part of the 19th century, bacteriology brought important transformations to epidemiology. However, its theoretical foundations suffered almost no change. Possibly the new challenges created by -the expanding colonial empires were the driving force in the evolution of epidemiology. As a science, it could not escape from the influence of social and political forces, It has only been recently, mainly in Latin America, that a search for alternatives to the dominating theoretical structure of epidemiology has taken place. The historical-materialist approach has given way to what is sometimes refered to as "social epidemiology". Epidemiology should be regarded as a science in which different theoretical approaches may coexist, as in history, sociology or physics.

    18. Epidemiology of low back pain.

      Science.gov (United States)

      Skovron, M L

      1992-10-01

      At present, although there have been many epidemiological studies of risk factors for low back pain, there are few risk factors established in prospective studies; and our understanding of them remains relatively crude. Individuals in jobs requiring manual materials handling, particularly repeated heavy lifting and lifting while twisting, are at increased risk of back pain leading to work absence. In addition, exposure to whole-body vibration and job requirements for static postures are associated with back pain. Individual trunk strength has not been consistently demonstrated as associated with back pain; although there is some suggestion that when work requirements for heavy lifting exceed individual capacities, back pain is more likely to occur. The pattern of peak age at onset in the 20's is consistent with back pain development early in working life. Among other individual characteristics, only cigarette smoking has consistently been associated with back pain; and the biological mechanism for this finding is not understood. Evidence with respect to spinal flexibility, aerobic capacity, educational attainment and other variables is suggestive but not consistent. There is some evidence that the individual's relation to work, expressed as job satisfaction or supervisor rating, is also related to work absence due to back pain. While it is possible to describe, however crudely, the characteristics placing people at risk for back pain leading to work absence and/or medical attention, the problem of predicting chronicity and thus identifying patients for more intensive clinical intervention remains unresolved. At this time, only age of the patient and certain clinical features of the back pain such as the presence of sciatic symptoms, duration of the current episode, and history of prior episodes are consistently demonstrated predictors. In chronic patients, there is suggestive evidence that spinal flexibility, trunk strength, and certain psychological

    19. Epidemiology of ANCA associated vasculitis

      Directory of Open Access Journals (Sweden)

      Wenche Koldingsnes

      2009-10-01

      Full Text Available ANCA associated vasculitis (AAV comprises three syndromes with systemic vasculitis (Wegener’s granulomatosis (WG, Churg Strauss syndrome (CSS and icroscopic polyangiitis (MPA, which all involve small and medium sized vessels and are associated with antibodies against cytoplasmatic antibodies in neutrophils (ANCA. Polyarteritis nodosa (PAN is included in this review as it also affects medium sized vessels, and has many clinical findings in common with the AAV.Since the recognition of ANCA, increasing data have become available on the epidemiology of these vasculitidis. WG constitutes half of the AAV and its prevalence has increased from 30/million in the late 1980’s in the USA to 160/million in this century in northern Europe. The prevalence for the whole group of primary systemic vasculitides is now 300/million in Sweden. The annual incidence of WG increased from 6.0/million to 14/million during the 1990’s in Tromsø, but it is unknown if this is a true increase or the result of an increased awareness of the diagnosis. For the whole group of AAV, the annual incidence in most more recent studies is relatively constant over time and by geographical location, ranging from 13 to 21/million. Nonetheless there are interesting differences in the prevalence of specific vasculitis between different geographical areas, as well as for sub specificities of ANCA.There seems to be a South-North gradient for WG and PR3-ANCA with high figures reported from northern Europe and southern New Zealand. In European studies WG is 90% PR3-ANCA positive. MPA which is predominantly MPO-ANCA associated are more frequent in the Mediterranean countries and also has an increasing gradient towards east-Asia, as almost all AAV in China and Japan are diagnosed as MPA, predominantly MPO-ANCA positive.There are also some ethnic and gender differences. WG is most prevalent among Caucasians in the USA and in people with European ancestors in Paris and in New Zealand, less

    20. Epidemiology of human African trypanosomiasis

      Directory of Open Access Journals (Sweden)

      Franco JR

      2014-08-01

      Full Text Available Jose R Franco,1 Pere P Simarro,1 Abdoulaye Diarra,2 Jean G Jannin1 1World Health Organization, Control of Neglected Tropical Diseases, Innovative and Intensified Disease Management, Geneva, Switzerland; 2World Health Organization, Inter Country Support Team for Central Africa, Regional Office for Africa, Libreville, Gabon Abstract: Human African trypanosomiasis (HAT, or sleeping sickness, is caused by Trypanosoma brucei gambiense, which is a chronic form of the disease present in western and central Africa, and by Trypanosoma brucei rhodesiense, which is an acute disease located in eastern and southern Africa. The rhodesiense form is a zoonosis, with the occasional infection of humans, but in the gambiense form, the human being is regarded as the main reservoir that plays a key role in the transmission cycle of the disease. The gambiense form currently assumes that 98% of the cases are declared; the Democratic Republic of the Congo is the most affected country, with more than 75% of the gambiense cases declared. The epidemiology of the disease is mediated by the interaction of the parasite (trypanosome with the vectors (tsetse flies, as well as with the human and animal hosts within a particular environment. Related to these interactions, the disease is confined in spatially limited areas called “foci”, which are located in Sub-Saharan Africa, mainly in remote rural areas. The risk of contracting HAT is, therefore, determined by the possibility of contact of a human being with an infected tsetse fly. Epidemics of HAT were described at the beginning of the 20th century; intensive activities have been set up to confront the disease, and it was under control in the 1960s, with fewer than 5,000 cases reported in the whole continent. The disease resurged at the end of the 1990s, but renewed efforts from endemic countries, cooperation agencies, and nongovernmental organizations led by the World Health Organization succeeded to raise awareness and

    1. Pasado, presente y futuro cercano de los materiales para uso en implantes óseos biodegradables

      Directory of Open Access Journals (Sweden)

      Clara Eugenia Plazas Bonilla

      2011-05-01

      Full Text Available El manejo de fracturas y defectos óseos procura la regeneración del tejido óseo respetando su anatomía y buscando recuperar su funcionalidad. El logro de este objetivo se inició en el siglo XVII con el uso de injertos de origen animal o humano, y ha llegado en la actualidad al uso de implantes, dispositivos elaborados en materiales naturales o sintéticos que comportan una gran variedad de propiedades químicas, físicas y biológicas. Las investigaciones en el área continúan encaminándose a la solución de los inconvenientes que presentan los injertos: las reacciones inmunológicas, los riesgos de contaminación, la ausencia de donantes, la necesidad de varias intervenciones quirúrgicas y el riesgo de transmisión de enfermedades. Es por ello que, tanto la investigación básica como aplicada, se han encaminado de igual forma en el ámbito de la biología del desarrollo e investigación con células madre, como en el campo del exploración de nuevos biomateriales. Esta tendencia es evidente al observar los numerosos estudios en relación con el uso de materiales metálicos, poliméricos, cerámicos y, en la actualidad, de los materiales compuestos o híbridos con uso potencial en implantes ortopédicos. Muchos de estos materiales, al cumplir con condiciones de biocompatibilidad y toxicidad, pueden ser usados en el diseño de materiales biodegradables y son el elemento de partida para el surgimiento de numerosas líneas de investigación en biomateriales. En este documento, a partir de la identificación de los períodos de avance en el estudio de biomateriales, se reseñan las bondades y restricciones de estos diferentes grupos que han sido investigados para ser usados en regeneración ósea y se plantean las directrices que a mediano plazo se han de seguir en el campo de los materiales biodegradables, temática en la que hay un extenso camino por recorrer en el ámbito de la ciencia y tecnología de los materiales.

    2. Tiempo para un cambio

      Science.gov (United States)

      Woltjer, L.

      1987-06-01

      En la reunion celebrada en diciembre dei ano pasado informe al Consejo de mi deseo de terminar mi contrato como Director General de la ESO una vez que fuera aprobado el proyecto dei VLT, que se espera sucedera hacia fines de este aAo. Cuando fue renovada mi designacion hace tres aAos, el Consejo conocia mi intencion de no completar los cinco aAos dei contrato debido a mi deseo de disponer de mas tiempo para otras actividades. Ahora, una vez terminada la fase preparatoria para el VLT, Y habiendose presentado el proyecto formalmente al Consejo el dia 31 de marzo, y esperando su muy probable aprobacion antes dei termino de este ano, me parece que el 10 de enero de 1988 presenta una excelente fecha para que se produzca un cambio en la administracion de la ESO.

    3. El enfoque epidemiologico del sistema de salud de Cuba The epidemiologic approach of the Cuban health system

      Directory of Open Access Journals (Sweden)

      Silvia Martínez Calvo

      1999-08-01

      Full Text Available El reconocimiento internacional a los logros del sistema de salud cubano, la estabilidad -en ocasiones cuestionada- de los indicadores de salud de la población, y los ingentes recursos humanos y materiales invertidos para desarrollar las políticas y estrategias sanitarias nacionales, constituyen un excelente ámbito para analizar la contribución de la Epidemiología a esos positivos resultados en el campo de la salud. Surgen dos provocadoras interrogantes: ¿Estuvo el sistema de salud epidemiológicamente orientado? ¿Las acciones realizadas consienten la propuesta de una Escuela Cubana de Epidemiología?. El propósito del trabajo es ofrecer respuestas a estas interrogantes através de una valoración crítica sobre la probable orientación epidemiológica del sistema y la incorporación o no del pensamiento epidemiológico en las estrategias sanitarias que se diseñan y desarrollan nacionalmente. Contribuye al análisis, una división arbitraria pero notoria: el Seminario sobre "Usos y perspectivas de la Epidemiología" realizado en Buenos Aires, que a partir de su fecha de realización en 1983, trazó pautas para el desempeño epidemiológico en la Región. Esa dicotomía - antes y después del Seminario- configuró los escenarios nacionales para la práctica epidemiológica en los niveles académico, investigativo y en los servicios, sostenidos en 4 pilares básicos: voluntad política, comunidad organizada y concientizada, sistema de salud con accesibilidad, cobertura total y financiamiento amplio, y por último, recursos humanos altamente calificados. El sistema de salud transita por etapas evolutivas cuyo bosquejo aporta elementos para reconocer su probable orientación epidemiológica, y su vinculación o no vinculación con las diferentes corrientes de pensamiento vigentes en cada etapa. Otro aspecto desafiante en el tema, es la propuesta de una Escuela Cubana de Epidemiología, y la valoración realizada en ese sentido, intenta

    4. Human immunodeficiency virus, AIDS, and drug consumption in South America and the Caribbean: epidemiological evidence and initiatives to curb the epidemic El virus de la inmunodeficiencia humana, el sida y el consumo de drogas en América del Sur y el Caribe: pruebas epidemiológicas e iniciativas para frenar la epidemia

      Directory of Open Access Journals (Sweden)

      Mariana A Hacker

      2005-11-01

      pertenecientes a instituciones internacionales y redes regionales cuya labor comprende medidas contra el uso indebido de sustancias o el virus de la inmunodeficiencia humana y el sida, más los resúmenes de conferencias y reuniones. RESULTADOS: Aunque sigue habiendo aspectos que se desconocen, hay cada vez más datos que apuntan al importante papel que desempeña el uso de cocaína inyectada en las epidemias que aquejan al Brasil y al Cono Sur. Las áreas caribeña y andina hasta ahora se han visto poco afectadas por la diseminación del consumo de drogas inyectadas y sus consecuencias, pero en países del Cono Sur la situación ha venido cambiando, observándose ahora una mayor prevalencia de prácticas peligrosas relacionadas con la inyección. La mayor disponibilidad actual de la heroína en el Área Andina y el abuso del crack (basuco y su impacto en la transmisión del virus de la inmunodeficiencia humana por la vía sexual en muchas ciudades se suman a los otros retos planteados. Estrategias orientadas a reducir el peligro se han establecido en la mayor parte del territorio brasileño y están cobrando impulso en la Argentina, pero en otros países de la Región sigue habiendo obstáculos en forma de leyes restrictivas y la falta de un apoyo más amplio. CONCLUSIÓN: Es menester fomentar una mayor participación de los países latinoamericanos y caribeños en los protocolos de investigación y en los debates en torno a experiencias fructíferas y fallidas, todo con el fin de reducir a un mínimo las actuales barreras que impiden adoptar medidas eficaces para frenar la epidemia de infección por el virus de la inmunodeficiencia humana y el sida en esta región.

    5. Breast Cancer Epidemiology in Puerto Rico

      Science.gov (United States)

      2014-08-01

      Preparándonos para vencer: Programa para identificar las necesidades de información y apoyo para las mujeres sobrevivientes de cáncer de mama...of recruitment. Controls were identified from participants in the Estudio Continuo de Salud (ECS), a National Health Survey in Puerto Rico, which was...menopausal at interview, as expected by the age criteria for inclusion . Eighty eight percent (88%) of the participants had their first pregnancy before age

    6. Should the history of epidemiology be taught in epidemiology training programs?

      Science.gov (United States)

      Laskaris, Zoey; Morabia, Alfredo

      2015-01-01

      Currently, there is no evidence concerning the presence of historical content in the epidemiology curricula of the United States and abroad. Similarly, it is not known how epidemiologists view this topic in the context of master's or doctoral level course work. We attempted to fill these knowledge gaps with data from 2 online surveys-Survey I administered to persons in charge of all epidemiology training programs in North America and Survey II to epidemiologists practicing around the world. A substantial minority (39%) of graduate programs in epidemiology in the United States teach a course on the history of the field. In both surveys, the most common reasons selected for teaching such a course were "To build a sense of identity as an epidemiologist" and "As a tool for achieving a deeper understanding into specific methods and concepts." The majority of respondents, from 63 countries, agreed that the history of epidemiology should be included in curricula for graduate students in epidemiology.

    7. Epidemiology of eating disorders in Africa.

      Science.gov (United States)

      van Hoeken, Daphne; Burns, Jonathan K; Hoek, Hans W

      2016-11-01

      This is the first review of studies on the epidemiology of eating disorders on the African continent. The majority of articles found through our search did not assess formal diagnoses, but only screened for eating attitudes and behaviors. Only four studies - including only one recent study - provided specific epidemiological data on anorexia nervosa, bulimia nervosa, and/or eating disorder not otherwise specified (EDNOS). No cases of anorexia nervosa according to Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria were found among a total of 1476 (young) females. The combined point-prevalence rate of bulimia nervosa is 0.87% (95% CI 0.22-1.51) and of EDNOS is 4.45% (95% CI 2.74-6.16) in young women in Africa. The epidemiological study of eating disorders in Africa is still in its infancy. Over time in total four studies providing epidemiological data on specific, formally assessed eating disorders were found. No cases of anorexia nervosa were reported in African epidemiological studies, which concurs with the very low prevalence rates of anorexia nervosa in Latin Americans and in African Americans in the USA. With the DSM-5 criteria for anorexia nervosa, some women in the African studies would have fulfilled the criteria for anorexia nervosa. The prevalence rate of bulimia nervosa in women in Africa is within the range reported for western populations, as well as African Americans and Latin Americans.

    8. Radiation carcinogenesis: Epidemiology and biological significance

      International Nuclear Information System (INIS)

      Boice, J.D.; Fraumeni, J.F.

      1984-01-01

      Epidemiologic studies of populations exposed to radiation have led to the identification of a preventable cause of cancer, but in the long run perhaps the most important contribution of radiation studies will be to provide insights into the basic processes of human carcinogenesis. In this volume, key investigators of major epidemiologic projects summarize their observations to date, including information to help assess the effects of low-level exposures. Experimentalists and theorists emphasize the relevance of laboratory and epidemiologic data in elucidating carcinogenic risks and mechanisms in man. This volume was prepared with several objectives in mind: (a) organize and synthesize knowledge on radiation carcinogenesis through epidemiologic and experimental approaches; (b) illustrate and explore ways of utilizing this information to gain insights into the fundamental mechanisms of cancer development; (c) stimulate the formation of hypotheses suited to experimental or epidemiologic testing, theoretical modeling, and multidisciplinary approaches; and (d) identify recent advances that clarify dose-response relationships and the influence of low-dose exposures, provide leads to carcinogenic mechanisms and host-environmental interactions, and suggest strategies for future research and preventive action

    9. Methodological exploratory study applied to occupational epidemiology

      Energy Technology Data Exchange (ETDEWEB)

      Carneiro, Janete C.G. Gaburo; Vasques, MOnica Heloisa B.; Fontinele, Ricardo S.; Sordi, Gian Maria A. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)]. E-mail: janetegc@ipen.br

      2007-07-01

      The utilization of epidemiologic methods and techniques has been object of practical experimentation and theoretical-methodological reflection in health planning and programming process. Occupational Epidemiology is the study of the causes and prevention of diseases and injuries from exposition and risks in the work environment. In this context, there is no intention to deplete such a complex theme but to deal with basic concepts of Occupational Epidemiology, presenting the main characteristics of the analysis methods used in epidemiology, as investigate the possible determinants of exposition (chemical, physical and biological agents). For this study, the social-demographic profile of the IPEN-CNEN/SP work force was used. The knowledge of this reference population composition is based on sex, age, educational level, marital status and different occupations, aiming to know the relation between the health aggravating factors and these variables. The methodology used refers to a non-experimental research based on a theoretical methodological practice. The work performed has an exploratory character, aiming a later survey of indicators in the health area in order to analyze possible correlations related to epidemiologic issues. (author)

    10. Methodological exploratory study applied to occupational epidemiology

      International Nuclear Information System (INIS)

      Carneiro, Janete C.G. Gaburo; Vasques, MOnica Heloisa B.; Fontinele, Ricardo S.; Sordi, Gian Maria A.

      2007-01-01

      The utilization of epidemiologic methods and techniques has been object of practical experimentation and theoretical-methodological reflection in health planning and programming process. Occupational Epidemiology is the study of the causes and prevention of diseases and injuries from exposition and risks in the work environment. In this context, there is no intention to deplete such a complex theme but to deal with basic concepts of Occupational Epidemiology, presenting the main characteristics of the analysis methods used in epidemiology, as investigate the possible determinants of exposition (chemical, physical and biological agents). For this study, the social-demographic profile of the IPEN-CNEN/SP work force was used. The knowledge of this reference population composition is based on sex, age, educational level, marital status and different occupations, aiming to know the relation between the health aggravating factors and these variables. The methodology used refers to a non-experimental research based on a theoretical methodological practice. The work performed has an exploratory character, aiming a later survey of indicators in the health area in order to analyze possible correlations related to epidemiologic issues. (author)

    11. [Epidemiological imaginary in Campania Region].

      Science.gov (United States)

      Greco, Pietro

      2012-01-01

      The interviews on the epidemiological imaginary, collected within the framework of the project Sebiorec,(1) clearly demonstrate that also in Campania, on the border between the provinces of Naples and Caserta - where the issue of waste and land devastation take forms that are unprecedented compared to any other part of Europe - there is a widespread, strong, sacrosanct demand of participation in environment and health management. The request of deliberative ecological democracy is pressing.(2) There is an urgent need to meet that plethora of rights emerging in the "knowledge society" and in the "risk society" that someone has called "rights for scientific citizenship."(3) This request of the population of Campania, net of local cultural specificity, it is quite similar to that of the people of any other region of Europe. The context in which this request of participation is expressed, however, is quite different. Not only and not just for that real or perceived social pre-modern and familist web that would replace a modern civil society in Campania and all across the Southern Italian regions, but also and especially for some structural causes that we here try to list. Campania is a unique region in Europe - in many ways different even from other regions of southern Italy - due to the conjunction of at least five factors, not independent from each other. 1) The presence of a widespread organized crime which, in many areas, metropolitan and non-metropolitan alike, and especially in the provinces of Naples and Caserta, is a sort of state against the State and has one of its main levers of power and a major source of its wealth in the illegal control of the territory, in its different dimensions (military, but also economic, social and even cultural). 2) A huge social and economic disintegration, exacerbated in the last twenty years by a process of deindustrialization (until the early nineties Naples was the fifth industrial city of Italy, today it is a desert where

    12. Para-Hermitian and para-quaternionic manifolds

      International Nuclear Information System (INIS)

      Ivanov, S.; Zamkovoy, S.

      2003-10-01

      A set of canonical para-Hermitian connections on an almost para-Hermitian manifold is defined. A Para-hermitian version of the Apostolov-Gauduchon generalization of the Goldberg-Sachs theorem in General Relativity is given. It is proved that the Nijenhuis tensor of a Nearly para-Kaehler manifolds is parallel with respect to the canonical connection. Salamon's twistor construction on quaternionic manifold is adapted to the para-quaternionic case. A locally conformally hyper-para-Kaehler (hypersymplectic) flat structure with parallel Lee form on the Kodaira-Thurston complex surfaces modeled on S 1 x SL (2, R)-tilde is constructed. Anti-self-dual locally conformally hyper-para-Kaehler (hypersymplectic) neutral metrics with non vanishing Weyl tensor are obtained on the Inoe surfaces. An example of anti-self-dual neutral metric which is not locally conformally hyper-para-Kaehler (hypersymplectic) is constructed. (author)

    13. Para-Hermitian and para-quaternionic manifolds

      Energy Technology Data Exchange (ETDEWEB)

      Ivanov, S [University of Sofia ' St. Kl. Ohridski' , Faculty of Mathematics and Informatics, Sofia (Bulgaria) and Abdus Salam International Centre for Theoretical Physics, Trieste (Italy); Zamkovoy, S [University of Sofia ' St. Kl. Ohridski' , Faculty of Mathematics and Informatics, Sofia (Bulgaria)

      2003-10-01

      A set of canonical para-Hermitian connections on an almost para-Hermitian manifold is defined. A Para-hermitian version of the Apostolov-Gauduchon generalization of the Goldberg-Sachs theorem in General Relativity is given. It is proved that the Nijenhuis tensor of a Nearly para-Kaehler manifolds is parallel with respect to the canonical connection. Salamon's twistor construction on quaternionic manifold is adapted to the para-quaternionic case. A locally conformally hyper-para-Kaehler (hypersymplectic) flat structure with parallel Lee form on the Kodaira-Thurston complex surfaces modeled on S{sup 1} x SL (2, R)-tilde is constructed. Anti-self-dual locally conformally hyper-para-Kaehler (hypersymplectic) neutral metrics with non vanishing Weyl tensor are obtained on the Inoe surfaces. An example of anti-self-dual neutral metric which is not locally conformally hyper-para-Kaehler (hypersymplectic) is constructed. (author)

    14. [Scientific, practical and educational aspects of clinical epidemiology].

      Science.gov (United States)

      Briko, N I

      2012-01-01

      This article defines clinical epidemiology and describes its goal and objectives. The author claims that clinical epidemiology is a section of epidemiology which underlies the development of evidence-based standards for diagnostics, treatment and prevention and helps to select the appropriate algorithm for each clinical case. The study provides a comprehensive overview of the relationship between clinical epidemiology and evidence-based medicine. Epidemiological research is shown to be methodological basis of clinical epidemiology and evidence-based medicine with randomized controlled trials being the "gold standard" for obtaining reliable data. The key stages in the history of clinical epidemiology are discussed and further development of clinical epidemiology and the integration of courses on clinical epidemiology in education is outlined for progress in medical research and health care practice.

    15. The Changing Epidemiology of Autism Spectrum Disorders.

      Science.gov (United States)

      Lyall, Kristen; Croen, Lisa; Daniels, Julie; Fallin, M Daniele; Ladd-Acosta, Christine; Lee, Brian K; Park, Bo Y; Snyder, Nathaniel W; Schendel, Diana; Volk, Heather; Windham, Gayle C; Newschaffer, Craig

      2017-03-20

      Autism spectrum disorder (ASD) is a complex neurodevelopmental condition with lifelong impacts. Genetic and environmental factors contribute to ASD etiology, which remains incompletely understood. Research on ASD epidemiology has made significant advances in the past decade. Current prevalence is estimated to be at least 1.5% in developed countries, with recent increases primarily among those without comorbid intellectual disability. Genetic studies have identified a number of rare de novo mutations and gained footing in the areas of polygenic risk, epigenetics, and gene-by-environment interaction. Epidemiologic investigations focused on nongenetic factors have established advanced parental age and preterm birth as ASD risk factors, indicated that prenatal exposure to air pollution and short interpregnancy interval are potential risk factors, and suggested the need for further exploration of certain prenatal nutrients, metabolic conditions, and exposure to endocrine-disrupting chemicals. We discuss future challenges and goals for ASD epidemiology as well as public health implications.

    16. Genesis of Preeclampsia: An Epidemiological Approach

      Science.gov (United States)

      Salvador-Moysén, Jaime; Martínez-López, Yolanda; Ramírez-Aranda, José M.; Aguilar-Durán, Marisela; Terrones-González, Alberto

      2012-01-01

      There are analyzed some of the main aspects related to the causality of preeclampsia, privileging two types of models: the clinic model and the epidemiologic model, first one represented by the hypothesis of the reduced placental perfusion and the second one considering the epidemiologic findings related to the high levels of psychosocial stress and its association with preeclampsia. It is reasoned out the relevance of raising the causality of the disease from an interdisciplinary perspective, integrating the valuable information generated from both types, clinical and epidemiologic, and finally a tentative explanatory model of preeclampsia is proposed, the subclinical and sociocultural aspects that predispose and trigger the disease are emphasized making aspects to stand out: the importance of reduced placental perfusion as an indicator of individual risk, and the high levels of physiological stress, as a result of the unfavorable conditions of the psychosocial surroundings (indicator of population risk) of the pregnant women. PMID:22462008

    17. Association Between Cannabis and Psychosis: Epidemiologic Evidence.

      Science.gov (United States)

      Gage, Suzanne H; Hickman, Matthew; Zammit, Stanley

      2016-04-01

      Associations between cannabis use and psychotic outcomes are consistently reported, but establishing causality from observational designs can be problematic. We review the evidence from longitudinal studies that have examined this relationship and discuss the epidemiologic evidence for and against interpreting the findings as causal. We also review the evidence identifying groups at particularly high risk of developing psychosis from using cannabis. Overall, evidence from epidemiologic studies provides strong enough evidence to warrant a public health message that cannabis use can increase the risk of psychotic disorders. However, further studies are required to determine the magnitude of this effect, to determine the effect of different strains of cannabis on risk, and to identify high-risk groups particularly susceptible to the effects of cannabis on psychosis. We also discuss complementary epidemiologic methods that can help address these questions. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

    18. Web tools for molecular epidemiology of tuberculosis.

      Science.gov (United States)

      Shabbeer, Amina; Ozcaglar, Cagri; Yener, Bülent; Bennett, Kristin P

      2012-06-01

      In this study we explore publicly available web tools designed to use molecular epidemiological data to extract information that can be employed for the effective tracking and control of tuberculosis (TB). The application of molecular methods for the epidemiology of TB complement traditional approaches used in public health. DNA fingerprinting methods are now routinely employed in TB surveillance programs and are primarily used to detect recent transmissions and in outbreak investigations. Here we present web tools that facilitate systematic analysis of Mycobacterium tuberculosis complex (MTBC) genotype information and provide a view of the genetic diversity in the MTBC population. These tools help answer questions about the characteristics of MTBC strains, such as their pathogenicity, virulence, immunogenicity, transmissibility, drug-resistance profiles and host-pathogen associativity. They provide an integrated platform for researchers to use molecular epidemiological data to address current challenges in the understanding of TB dynamics and the characteristics of MTBC. Copyright © 2011. Published by Elsevier B.V.

    19. The globalization of epidemiology: introductory remarks.

      Science.gov (United States)

      Pearce, Neil

      2004-10-01

      We are all living in the era of globalization, and like it or not, it is going to change the way we practice epidemiology, the kinds of questions we ask, and the methods we use to answer them. Increasingly, pubic health problems are being shifted from rich countries to poor countries and from rich to poor populations within Western countries. There is increasing interest and concern about the situation in non-Western populations on the part of Western epidemiologists, with regards to collaborative research, skills transfer, and 'volunteerism' to enable the 'benefits' of Western approaches to epidemiology to be shared by the non-Western world. However, most existing collaborations benefit Western epidemiologists rather than the countries in which the research is conducted. Even when research in non-Western populations is conducted as a genuine collaboration, it can too often 'export failure' from the West. On the other hand, non-Western epidemiologists are increasingly developing new and innovative approaches to health research that are more appropriate to the global public health issues they are addressing. These include recognition of the importance of context and the importance of diversity and local knowledge, and a problem-based approach to addressing the major public health problems using appropriate technology. These debates formed the background for a plenary session on 'International Epidemiology and International Health' at the recent International Epidemiological Association (IEA) meeting in Montreal, and the papers from this session are presented here. The development of a truly global epidemiology can not only better address the public health problems in non-Western populations, but can shed light on the current limitations of epidemiology in addressing the major public health problems in the West.

    20. Los alumnos de ciencias ambientales ¿disponen de habilidades para la investigación?

      OpenAIRE

      Cobos López, Juan

      2015-01-01

      La investigación en Ciencias Ambientales, requiere de conocimientos de Estadística y epidemiología. En la Universidad de Alcalá, la estadística y epidemiología (incluido en la asignatura: toxicología Ambiental y salud Pública), disponen de 6 créditos. El objetivo del estudio, es conocer habilidades para elaborar un proyecto de investigación en Ciencias Ambientales, en alumnos de 2º Curso .Universidad de Alcalá durante 2014-2015. Se diseña una encuesta, con 15 preguntas abiertas, con carácter ...

    1. Mathematical and statistical approaches to AIDS epidemiology

      CERN Document Server

      1989-01-01

      The 18 research articles of this volume discuss the major themes that have emerged from mathematical and statistical research in the epidemiology of HIV. The opening paper reviews important recent contributions. Five sections follow: Statistical Methodology and Forecasting, Infectivity and the HIV, Heterogeneity and HIV Transmission Dynamics, Social Dynamics and AIDS, and The Immune System and The HIV. In each, leading experts in AIDS epidemiology present the recent results. Some address the role of variable infectivity, heterogeneous mixing, and long periods of infectiousness in the dynamics of HIV; others concentrate on parameter estimation and short-term forecasting. The last section looks at the interaction between the HIV and the immune system.

    2. Epidemiology and natural history of vestibular schwannomas

      DEFF Research Database (Denmark)

      Stangerup, Sven-Eric; Caye-Thomasen, Per

      2012-01-01

      This article describes various epidemiologic trends for vestibular schwannomas over the last 35 years, including a brief note on terminology. Additionally, it provides information on the natural history of tumor growth and hearing level following the diagnosis of a vestibular schwannoma. A treatm......This article describes various epidemiologic trends for vestibular schwannomas over the last 35 years, including a brief note on terminology. Additionally, it provides information on the natural history of tumor growth and hearing level following the diagnosis of a vestibular schwannoma...

    3. [Epidemiology of tumors in the construction industry].

      Science.gov (United States)

      Assennato, G; Cuccaro, F

      2012-01-01

      Many epidemiological studies, mostly with a case-control design, show an increased risk of cancer, in particular lung cancer, in construction workers. Asbestos is the occupational carcinogen considered for a long time the most important in this sector, but now it covers a residual role, at least in Italy. In this review the most recent studies are considered and the presence of other carcinogens, as crystalline silica, man-made mineral fibers, diesel exhausts, metals, solvents, UV rays, must be considered in risk evaluation also, possibly, for health and epidemiologic surveillance.

    4. Using mobile technology to conduct epidemiological investigations

      Directory of Open Access Journals (Sweden)

      Onicio Batista Leal Neto

      2015-02-01

      Full Text Available INTRODUCTION : The aim of this study was to report the experience of an epidemiological field survey for which data were collected and analyzed using tablets. METHODS : The devices used Epi Info 7 (Android version, which has been modeled a database with variables of the traditional form. RESULTS : Twenty-one households were randomly selected in the study area; 75 residents were registered and completed household interviews with socioeconomic and environmental risk variables. CONCLUSIONS : This new technology is a valuable tool for collecting and analyzing data from the field, with advantageous benefits to epidemiological surveys.

    5. Epidemiology of autoimmune diseases in Denmark

      DEFF Research Database (Denmark)

      Eaton, William W.; Rose, N.R.; Kalaydijan, A.

      2007-01-01

      An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co-morbidities in i......An epidemiologic study of the autoimmune diseases taken together has not been done heretofore. The National Patient Register of Denmark is used to estimate the population prevalence of 31 possible or probable autoimmune diseases. Record linkage is used to estimate 465 pairwise co...

    6. HCV and HCC molecular epidemiology

      Directory of Open Access Journals (Sweden)

      Flor H. Pujol

      2007-02-01

      Full Text Available

      iHepatitis C virus (HCV is a member of the family Flaviviridae, responsible for the majority of the non-A non-B post-transfusion hepatitis before 1990. Around 170 millions persons in the world are thought to be infected with this virus. A high number of HCV-infected people develop cirrhosis and from these, a significant proportion progresses to hepatocellular carcinoma (HCC. Six HCV genotypes and a large number of subtypes in each genotype have been described. Infections with HCV genotype 1 are associated with the lowest therapeutic success. HCV genotypes 1, 2, and 3 have a worldwide distribution. HCV subtypes 1a and 1b are the most common genotypes in the United States and are also are predominant in Europe, while in Japan, subtype 1b is predominant. Although HCV subtypes 2a and 2b are relatively common in America, Europe, and Japan, subtype 2c is found commonly in northern Italy. HCV genotype 3a is frequent in intravenous drug abusers in Europe and the United States. HCV genotype 4 appears to be prevalent in Africa and the Middle East, and genotypes 5 and 6 seem to be confined to South Africa and Asia, respectively. HCC accounts for approximately 6% of all human cancers. Around 500,000 to 1 million cases occur annually worldwide, with HCC being the fifth common malignancy in men and the ninth in women. HCC is frequently a consequence of infection by HBV and HCV. The first line of evidences comes from epidemiologic studies. While HBV is the most frequent cause of HCC in many countries of Asia and South America, both HBV and HCV are found at similar frequencies, and eventually HCV at a higher frequency than HBV, among HCC patients in Europe, North America, and Japan. The cumulative appearance rate of HCC might be higher for HCV

    7. ParaChoice Model.

      Energy Technology Data Exchange (ETDEWEB)

      Heimer, Brandon Walter [Sandia National Lab. (SNL-CA), Livermore, CA (United States); Levinson, Rebecca Sobel [Sandia National Lab. (SNL-CA), Livermore, CA (United States); West, Todd H. [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

      2017-12-01

      Analysis with the ParaChoice model addresses three barriers from the VTO Multi-Year Program Plan: availability of alternative fuels and electric charging station infrastructure, availability of AFVs and electric drive vehicles, and consumer reluctance to purchase new technologies. In this fiscal year, we first examined the relationship between the availability of alternative fuels and station infrastructure. Specifically, we studied how electric vehicle charging infrastructure affects the ability of EVs to compete with vehicles that rely on mature, conventional petroleum-based fuels. Second, we studied how the availability of less costly AFVs promotes their representation in the LDV fleet. Third, we used ParaChoice trade space analyses to help inform which consumers are reluctant to purchase new technologies. Last, we began analysis of impacts of alternative energy technologies on Class 8 trucks to isolate those that may most efficaciously advance HDV efficiency and petroleum use reduction goals.

    8. Universidades accesibles para todos

      Directory of Open Access Journals (Sweden)

      Roxana Stupp Kupiec

      2001-01-01

      Full Text Available Este trabajo pretende hacer conciencia sobrelos factores que inciden en la construcción colectiva deuniversidades dispuestas a innovar y transformar suideología, sus políticas, el currículum, los servicios estu-diantiles, la infraestructura física y administrativa y lasestrategias de comunicación e información, bajo el para-digma de la accesibilidad en el entorno. Se hace referen-cia al marco legal internacional y nacional que orientalas acciones que deben planificarse e implementarse enlas instituciones de Educación Superior.En la construcción de universidades accesibles para to-dos se requiere de un cambio en la concepción curricu-lar. Se analizan conceptos como la flexibilidad en la for-mación y el acceso a los planes de estudio para respondera las necesidades educativas de todos los estudiantes. Para promover estas transformaciones se proponen prin-cipios y prácticas tales como la interdisciplinareidad y lainclusión del tema de la discapacidad en todas las carre-ras. Además, se presentan ejemplos de aplicación en dife-rentes áreas del perfil profesional, en la formación deldocente universitario y en actividades de proyección so-cial, vida estudiantil e investigación. En el ámbito estu-diantil, se describen algunos servicios y procesos que sehan desarrollado en la Universidad de Costa Rica

    9. Educando para la ignorancia

      Directory of Open Access Journals (Sweden)

      Miguel Durán

      1996-06-01

      Full Text Available Más que describir una situación particular, los autores buscan con este escrito motivar al estudiante para que asuma posiciones críticas; así como dar un campanazo de alerta a los profesores, en relación a los conocimientos que transmiten a sus alumnos y la forma en que lo hacen; todo con el ánimo de generar verdaderos espacios de reflexión en la universidad.

    10. Epidemiology of chronic kidney disease in children

      NARCIS (Netherlands)

      Harambat, Jérôme; van Stralen, Karlijn J.; Kim, Jon Jin; Tizard, E. Jane

      2012-01-01

      In the past 30 years there have been major improvements in the care of children with chronic kidney disease (CKD). However, most of the available epidemiological data stem from end-stage renal disease (ESRD) registries and information on the earlier stages of pediatric CKD is still limited. The

    11. Epidemiology, course, and outcome of eating disorders

      NARCIS (Netherlands)

      Smink, Frederique R. E.; van Hoeken, Daphne; Hoek, Hans W.

      2013-01-01

      Purpose of reviewTo review the recent literature about the epidemiology, course, and outcome of eating disorders in accordance with the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).Recent findingsThe residual category eating disorder not otherwise specified'

    12. Epidemiological characterization of oral cancer. Study Protocol.

      Directory of Open Access Journals (Sweden)

      Alejandra Fernández

      2015-04-01

      Full Text Available Oral cancer is a disease of high impact globally. It ranks as the sixth more frequent one among all types of cancer. In spite of being a widely known pathology and easy access to the diagnosis, the lack of epidemiological data reported in the last 10 years in Chile called attention to. At the global level, the World Health Organization (WHO has developed a project called “GLOBOCAN” in order to collect epidemiological data of the global cancer, between its data, highlights the high incidence and high rate of mortality in the male sex, parameter that shows tendency to replicate in both America and Chile. In consequence to these data, a narrative review of the literature concerning the epidemiological profile of the different forms of oral cancer in the past 15 years was done. The diagnosis of oral cancer crosses transversely the Dental Science, forcing us to establish triads of work between oral and maxillofacial surgeons, pathologists and dentists of the various specialties, so as to allow a timely research, appropriate biopsies and histopathological studies finishes with the purpose of, on the one hand, obtain timely and accurate diagnostics, in addition, maintaining the epidemiological indicators.

    13. Epidemiological studies on cutaneous leishmaniasis in Ad ...

      African Journals Online (AJOL)

      http://www.cioms.ch/publications/layout_guide2002.p df. 4. Uzun S, Durdu M, Çulha G, Allahverdiyev AM,. Memişoğlu HR. Clinical features, epidemiology, and efficacy and safety of intralesional antimony treatment of cutaneous leishmaniasis: recent experience in Turkey. J. Parasitol 2004; 90: 853-859. 5. Uzun S, Uslular C, ...

    14. THE IMPORTANCE OF EPIDEMIOLOGY IN OPTOMETRY ABSTRACT

      African Journals Online (AJOL)

      LIVINGSTON

      and determinants of health-related states or events in specified ... populations. 2. to identify etiological factors (risk factors) in ... refraction and dispensing, the detection/diagnosis and management of disease in the eye, and rehabilitation of ... Optometry, epidemiology, blindness, refractive error, frequency, distribution.

    15. Epidemiological Pattern and Management of Pediatric Asthma ...

      African Journals Online (AJOL)

      EL-HAKIM

      Egypt J Pediatr Allergy Immunol 2008; 6(2): 51-56. 51. Epidemiological Pattern and Management of Pediatric Asthma. Review of Ain Shams Pediatric Hospital Chest Clinic Data. Cairo, Egypt 1995-2004. INTRODUCTION. Bronchial asthma is a major worldwide health problem, which has received increased attention in.

    16. Epidemiology of eating disorders in Africa

      NARCIS (Netherlands)

      van Hoeken, Daphne; Burns, Jonathan K.; Hoek, Hans W.

      2016-01-01

      Purpose of reviewThis is the first review of studies on the epidemiology of eating disorders on the African continent.Recent findingsThe majority of articles found through our search did not assess formal diagnoses, but only screened for eating attitudes and behaviors. Only four studies - including

    17. Epidemiological characteristics of childhood urolithiasis in Morocco

      African Journals Online (AJOL)

      Z. El Lekhlifi

      2016-04-22

      Apr 22, 2016 ... Abstract. Objectives: Due to the increase observed in the incidence of pediatric urolithiasis in the world, and the scarcity of studies of this pathology in Morocco, we assessed whether epidemiological characteristics of pediatric urolithiasis have a similar profile like in developed countries further we tried to ...

    18. Epidemiology of eating disorders in Africa

      NARCIS (Netherlands)

      van Hoeken, Daphne; Burns, Jonathan K.; Hoek, Hans W.

      Purpose of reviewThis is the first review of studies on the epidemiology of eating disorders on the African continent.Recent findingsThe majority of articles found through our search did not assess formal diagnoses, but only screened for eating attitudes and behaviors. Only four studies - including

    19. Epidemiology, course, and outcome of eating disorders

      NARCIS (Netherlands)

      Smink, Frederique R. E.; van Hoeken, Daphne; Hoek, Hans W.

      Purpose of reviewTo review the recent literature about the epidemiology, course, and outcome of eating disorders in accordance with the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5).Recent findingsThe residual category eating disorder not otherwise specified'

    20. Epidemiology and risk factors of schizophrenia

      Czech Academy of Sciences Publication Activity Database

      Janoutová, J.; Janáčková, P.; Šerý, Omar; Zeman, T.; Ambrož, P.; Kovalová, M.; Vařechová, K.; Hosák, L.; Jiřík, V.; Janout, V.

      2016-01-01

      Roč. 37, č. 1 (2016), s. 1-8 ISSN 0172-780X R&D Projects: GA MZd NT14504 Institutional support: RVO:67985904 Keywords : schizophrenia * risk factors * epidemiology Subject RIV: FQ - Public Health Care, Social Medicine Impact factor: 0.918, year: 2016

    1. Dietary fat and obesity : An epidemiologic perspective

      NARCIS (Netherlands)

      Seidell, Jacob C.

      1998-01-01

      The observation that dietary fat has an effect on weight gain and the development of obesity that is larger than would be expected on the basis of fat's energy value is mainly experimental. Several methodologic problems limit the interpretation of epidemiologic studies of the association between

    2. Dietary fat and obesity : an epidemiologic perspective

      NARCIS (Netherlands)

      Seidell, J C

      The observation that dietary fat has an effect on weight gain and the development of obesity that is larger than would be expected on the basis of fat's energy value is mainly experimental. Several methodologic problems limit the interpretation of epidemiologic studies of the association between

    3. Epidemiological and antibiotic susceptibility profiles of infectious ...

      African Journals Online (AJOL)

      2011-09-28

      Sep 28, 2011 ... profiles of infectious bacterial diarrhoea in Juba, ... a Field Epidemiology and Laboratory Training Program (FELTP) resident, Jomo Kenyatta University of Agriculture and Technology, Nairobi, ... Teaching Hospital (JTH), Al Sabah children's hospital, .... Only 12 (4.2%) participants reached higher education.

    4. A Genetic Epidemiological Study of Behavioral Traits

      NARCIS (Netherlands)

      N. Amin (Najaf)

      2011-01-01

      textabstractHuman behavioural genetics aims to unravel the genetic and environmental contributions to variations in human behaviour. Behaviour is a complex trait, involving multiple genes that are affected by a variety of other factors. Genetic epidemiological research of behaviour goes back to

    5. The epidemiology of inflammatory bowel disease

      DEFF Research Database (Denmark)

      Burisch, Johan; Munkholm, Pia

      2015-01-01

      and cancer risks. MATERIAL AND METHODS: Gold standard epidemiology data on the disease course and prognosis of patients with inflammatory bowel disease (IBD) are based on unselected population-based cohort studies. RESULTS: The incidence of ulcerative colitis (UC) and Crohn's disease (CD) has increased...

    6. Epidemiological, clinical and developmental aspects of chronic ...

      African Journals Online (AJOL)

      Introduction: Our objective in this study was to describe both the epidemiological and clinical aspects and the difficulties of management of childhood CKD stages 3-5 in Senegal in order to express recommendations. Materials and Methods: This was a retrospective study from January 2005 to December 2013 in the ...

    7. Epidemiology of HIV-1 and emerging problems

      NARCIS (Netherlands)

      Lukashov, V. V.; de Ronde, A.; de Jong, J. J.; Goudsmit, J.

      2000-01-01

      Broad use of antiretroviral drugs is becoming a factor that is important to consider for understanding the HIV-1 epidemiology. Since 1993, we observe that a proportion of new infections within major risk groups in Amsterdam is caused by azidothymidine (AZT)-resistant viruses. After the introduction

    8. An Epidemiological Approach to Staff Burnout.

      Science.gov (United States)

      Kamis, Edna

      This paper describes a conceptual model of staff burnout in terms of independent, intervening and dependent variables. Staff burnout is defined, symptoms are presented, and the epidemiological approach to burnout is descussed. Components of the proposed model, which groups determinants of mental health into three domains, consist of: (1)…

    9. Epidemiology, occupational hygiene and health physics

      International Nuclear Information System (INIS)

      Bonnell, J.A.

      1980-01-01

      The contribution of radiation protection practices to the practice of occupational medicine and hygiene is discussed. For example, accurate studies of a number of biological systems were stimulated. It is suggested that an accurate epidemiological assessment of workers exposed at or below the recommended radiation dose limits be undertaken. (H.K.)

    10. Lessons from sea louse and salmon epidemiology.

      Science.gov (United States)

      Groner, Maya L; Rogers, Luke A; Bateman, Andrew W; Connors, Brendan M; Frazer, L Neil; Godwin, Sean C; Krkošek, Martin; Lewis, Mark A; Peacock, Stephanie J; Rees, Erin E; Revie, Crawford W; Schlägel, Ulrike E

      2016-03-05

      Effective disease management can benefit from mathematical models that identify drivers of epidemiological change and guide decision-making. This is well illustrated in the host-parasite system of sea lice and salmon, which has been modelled extensively due to the economic costs associated with sea louse infections on salmon farms and the conservation concerns associated with sea louse infections on wild salmon. Consequently, a rich modelling literature devoted to sea louse and salmon epidemiology has been developed. We provide a synthesis of the mathematical and statistical models that have been used to study the epidemiology of sea lice and salmon. These studies span both conceptual and tactical models to quantify the effects of infections on host populations and communities, describe and predict patterns of transmission and dispersal, and guide evidence-based management of wild and farmed salmon. As aquaculture production continues to increase, advances made in modelling sea louse and salmon epidemiology should inform the sustainable management of marine resources. © 2016 The Author(s).

    11. Epidemiology and clinical profile of common musculoskeletal ...

      African Journals Online (AJOL)

      Epidemiology and clinical profile of common musculoskeletal diseases in patients with diabetes mellitus at Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia. ... or worsening of MSD. Keywords: musculoskeletal complications; diabetic foot; foot care; trigger finger; Dupuytren's contracture; stiff frozen shoulder ...

    12. Ethics and epidemiological research | Cullinan | Malawi Medical ...

      African Journals Online (AJOL)

      Journal Home > Vol 8, No 2 (1992) >. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register. Ethics and epidemiological research. T Cullinan. Abstract. No Abstract. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL ...

    13. Epidemiological surveillance, virulence and public health ...

      African Journals Online (AJOL)

      gulab pandove

      Epidemiological surveillance of drinking water from Punjab, India reported occurrence of Listeria spp. in 58.67% of Municipal ... water system by direct contamination of the water or through ... sis causes fever, diarrhea, muscle pain, headache, nau- ... with a yellow background (Rhamnose positive) or blue without a yellow ...

    14. Spatial evolutionary epidemiology of spreading epidemics.

      Science.gov (United States)

      Lion, S; Gandon, S

      2016-10-26

      Most spatial models of host-parasite interactions either neglect the possibility of pathogen evolution or consider that this process is slow enough for epidemiological dynamics to reach an equilibrium on a fast timescale. Here, we propose a novel approach to jointly model the epidemiological and evolutionary dynamics of spatially structured host and pathogen populations. Starting from a multi-strain epidemiological model, we use a combination of spatial moment equations and quantitative genetics to analyse the dynamics of mean transmission and virulence in the population. A key insight of our approach is that, even in the absence of long-term evolutionary consequences, spatial structure can affect the short-term evolution of pathogens because of the build-up of spatial differentiation in mean virulence. We show that spatial differentiation is driven by a balance between epidemiological and genetic effects, and this quantity is related to the effect of kin competition discussed in previous studies of parasite evolution in spatially structured host populations. Our analysis can be used to understand and predict the transient evolutionary dynamics of pathogens and the emergence of spatial patterns of phenotypic variation. © 2016 The Author(s).

    15. The changing epidemiology of Clostridium difficile infections

      NARCIS (Netherlands)

      Freeman, J.; Bauer, M. P.; Baines, S. D.; Corver, J.; Fawley, W. N.; Goorhuis, B.; Kuijper, E. J.; Wilcox, M. H.

      2010-01-01

      The epidemiology of Clostridium difficile infection (CDI) has changed dramatically during this millennium. Infection rates have increased markedly in most countries with detailed surveillance data. There have been clear changes in the clinical presentation, response to treatment, and outcome of CDI.

    16. Premium adjustment: actuarial analysis on epidemiological models ...

      African Journals Online (AJOL)

      In this paper, we analyse insurance premium adjustment in the context of an epidemiological model where the insurer's future financial liability is greater than the premium from patients. In this situation, it becomes extremely difficult for the insurer since a negative reserve would severely increase its risk of insolvency, ...

    17. Chloroquine induced pruritus - questionnaire based epidemiological ...

      African Journals Online (AJOL)

      Chloroquine (CQ) is a very useful drug with a broad spectrum of uses (as anti malarial, anti amoebiasis and for connective tissue diseases). A major side effect preventing or limiting its utilization in blacks is chloroquine induced pruritus (CP). A descriptive cross sectional questionnaire based epidemiological study of ...

    18. INICIATIVAS PARA EL CAMBIO

      Directory of Open Access Journals (Sweden)

      César Alfonso Defrancisco-Larrañaga

      2013-07-01

      Full Text Available El planeta no atraviesa por su mejor momento en materia de conservación y renovación de sus recursos naturales. Claramente en los últimos tiempos los recursos hídricos han venido haciéndose cada vez menores; el hombre ha notado con preocupación y vivido en carne propia este fenómeno, que de no ser tratado a tiempo, podría atentar contra la existencia misma. Esto lo ha alentado a buscar métodos que sirvan como solución para contrarrestar éste mal y crear conciencia entre sus iguales, para así poder garantizar su permanencia y la de su entorno durante muchas generaciones. En países desarrollados del continente europeo y en algunos lugares de América del norte, el uso de sistemas de reutilización y tratamiento de aguas grises y aprovechamiento de las aguas lluvias se ha convertido en una constante y nos están dando las pautas para poder seguir el ejemplo y así de esta manera poder aportar a la causa ambiental y a su vez crear un ahorro en nuestros gastos mensuales de consumo.

    19. Usando Investigación-Acción para unir la práctica con la teoría en sistemas. Examinando cualitativamente la teoría de adopción de tecnología en una pyme

      Directory of Open Access Journals (Sweden)

      Alejandro Javier Cataldo Cataldo

      2016-03-01

      Full Text Available A pesar de que es bien conocida la metodología Investigación-Acción (IA, los investigadores aún recomiendan incrementar su uso en sistemas de información. En este artículo se muestra cómo IA puede ser útil para investigadores de sistemas que quieran unir la teoría con la práctica. Específicamente, se describe cómo IA fue usado para validar el modelo de Aceptación Tecnológica (TAM en una pequeña empresa chilena: mientras los investigadores ayudaban a resolver los problemas de procesos en dos áreas de la compañía, al mismo tiempo, investigaban sobre la validez de TAM. Tras finalizar dos ciclos de IA, los resultados permitieron incrementar significativamente la productividad de uno de los departamentos y, al mismo tiempo, validar solo tres de los cuatro postulados básicos de TAM. Como conclusión se puede decir que IA es un enfoque útil para cerrar la brecha entre teoría y práctica, que además calza adecuadamente para investigaciones longitudinales y reduce los esfuerzos de búsqueda y negociación de casos, pero que al mismo tiempo exige altos montos de tiempo de trabajo de campo. Este artículo entrega directrices y recomendaciones de cómo aplicar IA y puede ser de interés para investigadores y estudiantes que deseen ayudar a organizaciones y, simultáneamente, incrementar el conocimiento científico.

    20. The changing epidemiology of group B streptococcus bloodstream infection

      DEFF Research Database (Denmark)

      Ballard, Mark S; Schønheyder, Henrik C; Knudsen, Jenny Dahl

      2016-01-01

      Background Population-based studies conducted in single regions or countries have identified significant changes in the epidemiology of invasive group B streptococcus (GBS) infection. However, no studies have concurrently compared the epidemiology of GBS infections among multiple different region...

    1. Epidemiología y estrategias de control para pertussis, una enfermedad resurgente

      OpenAIRE

      Ormazabal, Maximiliano

      2015-01-01

      Muchos países han registrado durante los últimos 20 años un aumento alarmante en la incidencia de Bordetella pertussis, el principal agente causal de la enfermedad respiratoria aguda conocida con el nombre de tos convulsa, pertussis o coqueluche. Argentina, por su parte, detectó a partir del año 2003 un aumento de casos sostenido llegando a una tasa de 16/100.000 habitantes en el año 2011. En dicho año también se registró el mayor número de fallecimientos asociados a la enfermedad (76 falleci...

    2. Epidemiology and the Tobacco Epidemic: How Research on Tobacco and Health Shaped Epidemiology.

      Science.gov (United States)

      Samet, Jonathan M

      2016-03-01

      In this article, I provide a perspective on the tobacco epidemic and epidemiology, describing the impact of the tobacco-caused disease epidemic on the field of epidemiology. Although there is an enormous body of epidemiologic evidence on the associations of smoking with health, little systematic attention has been given to how decades of research have affected epidemiology and its practice. I address the many advances that resulted from epidemiologic research on smoking and health, such as demonstration of the utility of observational designs and important parameters (the odds ratio and the population attributable risk), guidelines for causal inference, and systematic review approaches. I also cover unintended and adverse consequences for the field, including the strategy of doubt creation and the recruitment of epidemiologists by the tobacco industry to serve its mission. The paradigm of evidence-based action for addressing noncommunicable diseases began with the need to address the epidemic of tobacco-caused disease, an imperative for action documented by epidemiologic research. © The Author 2016. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

    3. ADHD in the Arab World: A Review of Epidemiologic Studies

      Science.gov (United States)

      Farah, Lynn G.; Fayyad, John A.; Eapen, Valsamma; Cassir,Youmna; Salamoun, Mariana M.; Tabet, Caroline C.; Mneimneh, Zeina N.; Karam, Elie G.

      2009-01-01

      Objective: Epidemiological studies on psychiatric disorders are quite rare in the Arab World. This article reviews epidemiological studies on ADHD in all the Arab countries. Method: All epidemiological studies on ADHD conducted from 1966 through th present were reviewed. Samples were drawn from the general community, primary care clinical…

    4. Epidemiology of Schizophrenia: Review of Findings and Myths

      OpenAIRE

      Messias, Erick; Chen, Chuan-Yu; Eaton, William W.

      2007-01-01

      By describing patterns of disease distribution within populations, identifying risk factors, and finding associations, epidemiological studies have contributed to our current understanding of schizophrenia. Advanced paternal age and the association with auto-immune diseases are some of the newly described epidemiological finding in schizophrenia epidemiology, shaping our current definition of schizophrenia. Though early intervention strategies have gained momentum, primary prevention of schiz...

    5. La epidemiología ocupacional en países en desarrollo Labor epidemiology in developing countries

      Directory of Open Access Journals (Sweden)

      Caristina Robaina Aguirre

      2004-04-01

      Full Text Available En el presente artículo se analiza de forma crítica la situación epidemiológica ocupacional existente en la mayoría de los países en vías de desarrollo. Se valoran además las enfermedades que con más frecuencia afectan a nuestras poblaciones, en particular a la población trabajadora, incluyendo grupos vulnerables como mujeres y niños que se ven obligados, por razones económicas y sociales, a trabajar en condiciones anormales e inseguras. También se pone de manifiesto el papel que juegan algunos países industrializados en el aumento de la contaminación ambiental en nuestro tercer mundo, con la consiguiente repercusión para la salud de sus poblaciones.The present article analyzes in a critical way the epidemiological situation at work that exists in most of the developing countries. Also the diseases that more frequently affect our populations, mainly the working population including the vulnerable groups such as women and children who are forced to work under poor and unsafe conditions because of economic and social reasons, were assessed. The role played by some industrial nations in the rise of environmental pollution in our third world, with the resulting impact on our populations´s health was stressed.

    6. para mejorar el %R

      Directory of Open Access Journals (Sweden)

      Alfredo Díaz Mata

      2001-01-01

      Full Text Available En este trabajo se revisan dos indicadores técnicos bursátiles que están estrechamente relacionados, el oscilador estocástico %K de Lane y el oscilador %R de Williams; asimismo, se evalúa el uso de dos mecanismos asociados con el primero y que no suelen utilizarse con el %R: el proceso de frenado (slowing y el uso de un promedio móvil del propio oscilador estocástico como disparadores de señales de compra y de venta. Realizando simulaciones con 27 acciones y el Índice de Precios y Cotizaciones de la Bolsa Mexicana de Valores se verifica la hipótesis principal y se comprueba que, efectivamente, en muchos casos, el uso del proceso de frenado con el oscilador %R de Williams permite tomar mejores decisiones. Por otro lado, se concluye que de los dos disparadores de señales el que mejor funciona, tanto para %K como para %R es el uso de cotas inferior y superior. Este artículo surgió en el curso de una investigación sobre el análisis técnico bursátil de acciones que se puede realizar en su totalidad por computadora y que, esencialmente, excluye el análisis gráfico. Uno de los propósitos del estudio es determinar si es posible, y bajo qué mecanismos, establecer un sistema de análisis bursátil que le permita al inversionista tomar decisiones de inversión en acciones en la Bolsa Mexicana de Valores sin tener que emplear la considerable cantidad de tiempo que es necesario para el análisis gráfico tradicional. Durante este estudio se realizó un análisis preliminar de unos 120 indicadores técnicos para, por un lado, conocerlos con cierto detalle y, por otra parte, aislar aquellos que prometían ser de utilidad para el objetivo de la investigación. Fue en este proceso cuando se detectó que existen dos indicadores que están relacionados y que permiten un análisis por separado que tiene, cuando menos, dos ventajas. En primer lugar está el placer que da a quien gusta de estos temas encontrarse con indicadores que, de acuerdo

    7. Direct progeny detection techniques and random epidemiology

      International Nuclear Information System (INIS)

      Mayya, Y.S.; Mishra, Rosaline; Sapra, B.K.

      2015-01-01

      Over the past 40 years, there has been considerable progress in the measurements methods and their application to the estimates of risks due to radon among general populations. The previous decade saw major development in this regard. It was the direct estimate of indoor radon risk from epidemiological studies in Europe and North America. These were important findings that demonstrated the presence of lung cancer risks at residential radon levels supplementing the generally used risks estimates at high exposures obtained from uranium miner's data. The residential radon epidemiological studies largely used radon concentration as a measure of exposure. The exposure to decay products, which are primarily the dose givers, are assumed to be proportional to the measured gas concentrations. Also, the presence of thoron was neglected in these studies. Although several corrections have appeared to these assessments, the question of variability of actual decay product exposures has largely remained unaddressed. In order to circumvent this limitation, passive techniques were developed to estimate the decay product concentrations directly using deposition monitors. These are based on detecting the alpha particles from decay products deposited on an absorber mounted LR-115 detectors. Known as Direct radon, and Thoron Progeny sensors (DRPS/DTPS), these have been further refined to separate fine fraction from the coarse fraction by wire-mesh capping techniques. Large number environmental calibration exercises and field data generation has been carried out on the progeny concentrations in Indian and some European environments. The development of progeny sensors offers a new tool for future epidemiology. Since in the Indian context, there exist no radon related epidemiological estimates of risk, it is time one conducts large scale studies to seek possible correlations between DRPS/DTPS data and lung cancer risks. While epidemiological studies in High background radiation areas

    8. Inmunopotenciadores para la acuicultura

      Directory of Open Access Journals (Sweden)

      Rocmira Pérez

      2014-04-01

      Full Text Available La acuicultura es una de las actividades económicas de mayor crecimiento para la producción de alimentos. Uno de sus principales retos es la obtención de grandes volúmenes de producción con la mayor calidad posible. Esto conlleva a una reducción de la aplicación de antibióticos y productos quimioterapéuticos. Una de las estrategias más prometedoras es la aplicación de inmunopotenciadores, principalmente en los cultivos intensivos. El objetivo de este trabajo fue revisar los principales inmunopotenciadores, así como las tendencias y retos de su uso mundial. Se resumen las particularidades moleculares y funcionales de los mismos y se hace énfasis en los más estudiados: levamisol, ß-glucanos, lipopolisacárido, vitamina C, extractos de plantas y hormonas. Todos estos compuestos de naturaleza heterogénea inciden mayoritariamente en los componentes de la inmunidad innata de los peces, fortaleciendo y potenciando la resistencia a enfermedades; adicionalmente algunos de ellos tienen funciones antiestrés y favorecen su crecimiento. Se concluye que los inmunopotenciadores constituyen una estrategia viable para reducir las pérdidas por problemas sanitarios en el sector de la acuicultura; pero aún quedan por solucionar aspectos como la vía de administración y la etapa de inmunización adecuada para cada especie y tipo de cultivo.

    9. Ha vuelto para mirarnos

      OpenAIRE

      Casalderrey, Francisco

      2008-01-01

      En cada entrega analizaremos un cuadro, mirándolo con ojos matemáticos. Con esa particular mirada, fruto de nuestra propia (de)formación. Y desde ese punto de vista haremos paseos por el arte y las matemáticas. Espero que el lector, como hago yo mismo, disfrute descubriendo más allá de lo que a simple vista distinguiría cualquiera. Al fin de cuentas, el arte, como las matemáticas, han sido creados para hacernos disfrutar.

    10. Interfaces para control cerebral

      OpenAIRE

      Spinelli, Enrique Mario

      2000-01-01

      La función de una interfaz para control cerebral basada en señales de electroencefalograma (EEG), en forma general denominada BCI (Brain control Interface), es establecer un enlace directo entre el cerebro y una máquina, sin utilizar acciones motoras directas. Una BCI permite realizar operaciones simples a partir de la interpretación de las señales de EEG. Su desarrollo está principalmente orientado hacia la ayuda a personas con discapacidades motoras severas, que poseen deterioros en el sist...

    11. Comunicar para la salud

      Directory of Open Access Journals (Sweden)

      Lic. Eva Bocco

      1998-01-01

      Full Text Available Con este trabajo quiero plantearles una inquietud en torno al rol que nos cabe a los comunicadores en el área de la salud desde la perspectiva de la comunicación para la salud. ¿Se puede pensar la salud pública desvinculada de la comunicación? ¿La comunicación es posible sin la existencia de salud en la comunidad? ¿Qué puede hacer un comunicador en el ministerio de salud? ¿Puede un estado desarrollar políticas de salud sin la presencia de la comunicación?

    12. Democracia para ciudadanos ciborgs

      Directory of Open Access Journals (Sweden)

      Juan Varela

      2007-07-01

      Full Text Available Enumera los instrumentos imprescindibles de la ciberpolítica para campañas electorales en España, cuando se renovaron los cargos municipales. La política vuelve a ser personal cuando ciudadanos y políticos se hablan cara a cara y cita varios ejemplos, reconociendo la recuperación de la comunicación directa. La ciberdemocracia es muy exigente. Los políticos prefieren la magia de la imagen. La sociedad no sabe como detener la propaganda viral que bombardea a los buscadores de red.

    13. Democracia para ciudadanos ciborgs

      OpenAIRE

      Juan Varela

      2007-01-01

      Enumera los instrumentos imprescindibles de la ciberpolítica para campañas electorales en España, cuando se renovaron los cargos municipales. La política vuelve a ser personal cuando ciudadanos y políticos se hablan cara a cara y cita varios ejemplos, reconociendo la recuperación de la comunicación directa. La ciberdemocracia es muy exigente. Los políticos prefieren la magia de la imagen. La sociedad no sabe como detener la propaganda viral que bombardea a los buscadores de red.

    14. Serie: Madera para construcción Acabados para madera

      OpenAIRE

      Sáenz-Muñoz, Marta; Instituto Tecnológico de Costa Rica

      2012-01-01

      Durante mucho tiempo, la madera ha sido utilizada como material de construcción para resolver principalmente objetivos estructurales; sin embargo, actualmente, el uso de la madera ha tomado mucho auge en la estética de las construcciones, para brindar apariencia y calidez. En la actualidad, el mercado ofrece una amplia gama productos para dar diversos “acabados” a la madera, los cuales sirven para resaltar la belleza de algunas de ellas, realzar características como el color y la veta, o bien...

    15. Epidemiology of cervical cancer in Latin America.

      Science.gov (United States)

      Capote Negrin, Luis G

      2015-01-01

      The basic aspects of the descriptive epidemiology of cervical cancer in Latin America are presented. A decrease in the incidence and mortality rates has been observed in the period from 2000 to 2012 in all countries across the region, this has not occurred at the same proportions, and in many countries, observed figures of incidence and mortality are among the highest levels in the world. In Latin America, calculating a mean measure of the numbers from the GLOBOCAN data from 2000 to 2012, we can observe a difference of up to fivefold of the incidence (Puerto Rico 9,73 Vs Bolivia 50,73) and almost seven times for mortality (Puerto Rico 3,3 Vs Nicaragua 21,67). A report of the epidemiology, risk factors, and evaluation of screening procedures regarding the possible impact of the human papillomavirus (HPV) vaccine I in the prevention of cervical cancer is presented.

    16. Epidemiology of systemic mastocytosis in Denmark

      DEFF Research Database (Denmark)

      Cohen, Sarah; Hoffmann, Stine Skovbo; Vestergaard, Hanne

      2014-01-01

      Mastocytosis is a heterogeneous group of diseases characterized by abnormal proliferation of mast cells. Systemic mastocytosis (SM), in which abnormal mast cells are present in tissues beyond the skin, is divided into seven subcategories with varying degrees of severity and prognosis. Very little......%), followed by SM with subtype unknown (n = 61; 11%), SM with associated clonal haematological non-mast cell lineage disease (n = 24; 4%), aggressive SM (n = 8; 2%), and mast cell leukaemia (n = 5; 1%). The incidence rate for SM (all subtypes including urticaria pigmentosa) was 0_89 per 100 000 per year...... to be overall relatively rare with notable variation by subtype for patient characteristics, survival and epidemiological measures. Keywords: aggressive systemic mastocytosis, indolent systemic mastocytosis, urticaria pigmentosa, epidemiology, Denmark....

    17. Epidemiological Concepts Regarding Disease Monitoring and Surveillance

      Directory of Open Access Journals (Sweden)

      Christensen Jette

      2001-03-01

      Full Text Available Definitions of epidemiological concepts regarding disease monitoring and surveillance can be found in textbooks on veterinary epidemiology. This paper gives a review of how the concepts: monitoring, surveillance, and disease control strategies are defined. Monitoring and surveillance systems (MO&SS involve measurements of disease occurrence, and the design of the monitoring determines which types of disease occurrence measures can be applied. However, the knowledge of the performance of diagnostic tests (sensitivity and specificity is essential to estimate the true occurrence of the disease. The terms, disease control programme (DCP or disease eradication programme (DEP, are defined, and the steps of DCP/DEP are described to illustrate that they are a process rather than a static MO&SS.

    18. Global epidemiology of hyperthyroidism and hypothyroidism.

      Science.gov (United States)

      Taylor, Peter N; Albrecht, Diana; Scholz, Anna; Gutierrez-Buey, Gala; Lazarus, John H; Dayan, Colin M; Okosieme, Onyebuchi E

      2018-05-01

      Thyroid hormones are essential for growth, neuronal development, reproduction and regulation of energy metabolism. Hypothyroidism and hyperthyroidism are common conditions with potentially devastating health consequences that affect all populations worldwide. Iodine nutrition is a key determinant of thyroid disease risk; however, other factors, such as ageing, smoking status, genetic susceptibility, ethnicity, endocrine disruptors and the advent of novel therapeutics, including immune checkpoint inhibitors, also influence thyroid disease epidemiology. In the developed world, the prevalence of undiagnosed thyroid disease is likely falling owing to widespread thyroid function testing and relatively low thresholds for treatment initiation. However, continued vigilance against iodine deficiency remains essential in developed countries, particularly in Europe. In this report, we review the global incidence and prevalence of hyperthyroidism and hypothyroidism, highlighting geographical differences and the effect of environmental factors, such as iodine supplementation, on these data. We also highlight the pressing need for detailed epidemiological surveys of thyroid dysfunction and iodine status in developing countries.

    19. Epidemiological Criminology”: Coming Full Circle

      Science.gov (United States)

      Lanier, Mark M.

      2009-01-01

      Members of the public health and criminal justice disciplines often work with marginalized populations: people at high risk of drug use, health problems, incarceration, and other difficulties. As these fields increasingly overlap, distinctions between them are blurred, as numerous research reports and funding trends document. However, explicit theoretical and methodological linkages between the 2 disciplines remain rare. A new paradigm that links methods and statistical models of public health with those of their criminal justice counterparts is needed, as are increased linkages between epidemiological analogies, theories, and models and the corresponding tools of criminology. We outline disciplinary commonalities and distinctions, present policy examples that integrate similarities, and propose “epidemiological criminology” as a bridging framework. PMID:19150901

    20. Epidemiology and risk assessment for radiation

      International Nuclear Information System (INIS)

      Badwe, R.A.

      2014-01-01

      The hazard and exposures from radiation are known with reasonable accuracy. However, at 'low levels' uncertainty persists as to whether the dose response relationship is linear and whether there is a dose threshold, below which there is no risk. Some have proposed that 'low' exposures to radiation may be beneficial, a hypothesis referred to as 'hormesis'. Over recent decades, various expert groups have adopted linear no-threshold dose-response models for radiation and cancer, based on review of epidemiological and biological evidence. The unexpected epidemic of thyroid cancer among children following the Chernobyl disaster was noticed. The research with epidemiological data and knowledge of the radionuclides to which the children were exposed is needed. Currently a debate concerning potential risks of high frequency electromagnetic radiation from mobile phones illustrates another need for further research

    1. Fibromyalgia: Prevalence, epidemiologic profiles and economic costs.

      Science.gov (United States)

      Cabo-Meseguer, Asensi; Cerdá-Olmedo, Germán; Trillo-Mata, José Luis

      2017-11-22

      Fibromyalgia is an idiopathic chronic condition that causes widespread musculoskeletal pain, hyperalgesia and allodynia. This review aims to approach the general epidemiology of fibromyalgia according to the most recent published studies, identifying the general worldwide prevalence of the disease, its basic epidemiological profiles and its economic costs, with specific interest in the Spanish and Comunidad Valenciana cases. Fibromyalgia affects, on average, 2.10% of the world's population; 2.31% of the European population; 2.40% of the Spanish population; and 3.69% of the population in the Comunidad Valenciana. It supposes a painful loss of the quality of life of the people who suffer it and the economic costs are enormous: in Spain is has been estimated at more than 12,993 million euros annually. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

    2. Listeriosis in Mexico: Clinical and epidemiological importance

      Directory of Open Access Journals (Sweden)

      Gloria Castañeda-Ruelas

      2014-11-01

      Full Text Available Listeriosis is caused by Listeria monocytogenes, an important food-borne disease due to its clinical forms, high mortality rate, and the economic impact in both clinical and food production industries. In Mexico, the lack of epidemiological surveillance systems leads to the need of accurate data on the incidence of listeriosis and its association with food-borne disease. In this paper, we present data about the presence of this bacterium in food, reports related to clinical cases of listeriosis, and information of diseases in which L. monocytogenes may be involved. However, in most of these cases the etiology was not established. Given this, there´s a need to inform and warn the appropriate entities, to define strategies for the mandatory search of L. monocytogenes through the whole food production chain and clinical suspects, for the epidemiological importance and control of listeriosis in Mexico.

    3. "Colaborar para Competir"

      Directory of Open Access Journals (Sweden)

      Martha Liliana Hijuelos-Cárdenas

      2015-06-01

      Full Text Available De acuerdo con Michael Porter, los Clusters se definen como “Una agrupación de empresas e instituciones relacionadas entre sí, pertenecientes a un mismo sector o segmento de mercado, que se encuentran próximas geográficamente y que colaboran para ser más competitivas”. Los Clusters son en última instancia una herramienta de competitividad basada en la cooperación de sus miembros, y es una de las estrategias recientes, en el país, para incrementar la productividad y competitividad y las apuestas productivas desde el nivel local. Y es precisamente esta cercanía geográfica de las empresas de un mismo sector, lo que a la vez que genera la competencia entre ellas, también les facilita el acceso a insumos y a conocimientos específicos y en última instancia les permite promover la innovación.

    4. Principios teatrales para docentes

      Directory of Open Access Journals (Sweden)

      R. Irene Arroyo Zúñiga

      2005-01-01

      Full Text Available Este trabajo pretende dar herramientas a los docentes para que puedan utilizarlas como parte de las actividades dentro de un plan de elección, en cualquier disciplina. Además encontrará una exposición de los elementos que componen el arte de la representación escénica, como son: 1. Expresión corporal; es la capacidad de expresar emociones partiendo únicamente de nuestro cuerpo. 2. Impostación; es la habilidad de proyectar la voz sin lastimar las cuerdas vocales. 3. Dicción; es la pronunciación correcta de las palabras. 4. Actuación; es la posibilidad de crear un personaje partiendo de los recursos expresivos y de la forma natural en que el alumno acostumbra a reaccionar. Técnica de improvisación, en éste artículo propongo una serie de seis pasos que pueden ser de gran ayuda a la hora de usar el teatro como recurso didáctico. El teatro a lo largo de la historia ha sido usado para transmitir conocimientos, valores, creencias y todo aspecto inherente a los individuos y su entorno social. Por lo tanto debemos aprovechar al máximo los beneficios que nos ofrece el teatro como educadores

    5. The epidemiology of depression across cultures

      OpenAIRE

      Kessler, Ronald C.; Bromet, Evelyn J.

      2013-01-01

      Epidemiological data are reviewed on the prevalence, course, socio-demographic correlates, and societal costs of major depression throughout the world. Major depression is estimated in these surveys to be a commonly-occurring disorder. Although estimates of lifetime prevalence and course vary substantially across countries for reasons that could involve both substantive and methodological processes, the cross-national data are clear in documenting meaningful lifetime prevalence with wide vari...

    6. THE DISCOUNTED REPRODUCTIVE NUMBER FOR EPIDEMIOLOGY

      OpenAIRE

      Reluga, Timothy C.; Medlock, Jan; Galvani, Alison

      2009-01-01

      The basic reproductive number, , and the effective reproductive number, , are commonly used in mathematical epidemiology as summary statistics for the size and controllability of epidemics. However, these commonly used reproductive numbers can be misleading when applied to predict pathogen evolution because they do not incorporate the impact of the timing of events in the life-history cycle of the pathogen. To study evolution problems where the host population size is changing, measur...

    7. Epidemiology of Pediatric Sports Injuries: Individual Sports

      OpenAIRE

      2005-01-01

      The objective of the book is to review comprehensively what is known about the distribution and determinants of injury rates in a variety of individual sports, and to suggest injury prevention measures and guidelines for further research. This book provides comprehensive compilation and critical analysis of epidemiological data over children's individual sports: including equestrian, gymnastics, martial arts, skiing and snowboarding, tennis, track and field, and wrestling. This book enc...

    8. Genetic epidemiology of Down syndrome in Iran

      OpenAIRE

      Manoochehr Shariati

      2005-01-01

      Down syndrome is the most common autosomal abnormality and occurs in approximately 1 per 700 live births. Down syndrome accounts for about one third of all moderate and sever mental handicaps in school-aged children. To reveal genetic epidemiology of Down syndrome, 545 karyotypes of referred cases to the author were evaluated. The frequencies of three cytogenetic variants of Down syndrome were trisomy 21 (77.5%), mosaicism (18%) and chromosomal translocation (4.5%). Male to female ratio was 1...

    9. Epidemiology of cancer-related venous thromboembolism

      OpenAIRE

      Wun, Ted; White, Richard H.

      2009-01-01

      Recent studies have better defined the epidemiology of venous thromboembolism (VTE) in cancer patients. The incidence is highest in patients who have metastatic disease at the time of presentation and who have fast growing, biologically aggressive cancers associated with a poor prognosis. The incidence is also high in patients with haematological cancers. Other specific risk factors that affect the incidence of VTE include undergoing invasive neurosurgery, the number of underlying chronic co-...

    10. Cocoa Polyphenols: Evidence from Epidemiological Studies.

      Science.gov (United States)

      Matsumoto, Chisa

      2018-01-01

      Accumulating evidence suggests potential preventive effects of chocolate/cocoa on the risk of cardio vascular disease (CVD). However, cocoa products also contain high levels of sugar and fat, which increase CVD risk factors. Even, the identity of the substance in chocolate/cocoa that has a favorable effect on CVD and CVD risk factors remains unclear, growing evidence from experimental studies suggests that cocoa polyphenols might be a major contributor to cardiovascular-protective effects. However, epidemiological studies, which are necessary to evaluate an association between the risk of CVD and cocoa polyphenol, remain sparse. We will discuss recent evidence regarding the association between cocoa polyphenol consumption and the risks of CVD and its risk factors by reviewing recent epidemiological studies. We shall also provide some guidance for patient counseling and will discuss the public health implications for recommending cocoa polyphenol consumption to prevent CVD. Epidemiological studies evaluating the association between cocoa polyphenol itself and the risk of CVD are sparse. However, evidence from limited epidemiological studies suggests that cocoa polyphenol consumption may lower the risk of CVD. Given the potential adverse effects of the consumption of cocoa products with high fat and sugar and the fact that the most appropriate dose of cocoa polyphenol for cardio-protective effects has not yet been established, health care providers should remain cautious about recommending cocoa/cocoa polyphenol consumption to their patients to reduce the risk of CVD, taking the characteristics of individual patients into careful consideration. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

    11. Epidemiologic studies based on the Chernobyl accident

      International Nuclear Information System (INIS)

      Beebe, G.

      1996-01-01

      There are great opportunities in the post-Chernobyl experience for significant epidemiologic research, perhaps even more in the area of disaster research than in the area of the human health effects of ionizing radiation. But the potential opportunity for learning the effects of radioiodine on the thyroid is very great and has aroused widespread national and international investigative interest. The opportunities for significant epidemiologic research are, however, severely limited currently by the worsening economic situation in Belarus and Ukraine, where the greatest exposure occurred, and by the lack of personnel trained in appropriate methods of study, the lack of modern equipment, the lack of supplies, the poor communication facilities, and the difficulties of accurate dose estimation. the disadvantages may or may not outweigh the obvious advantages of large numbers, the extensive direct thyroidal measurements made shortly after the accident in 1986, the magnitude of the releases of radioiodine, and the retention of the former Soviet system of universal medical care. Both the European Commission (EC) and the World Health Organization (WHO) have been working actively to strengthen the infrastructure of Russia, Belarus, and Ukraine. New scientific knowledge has yet to emerge from the extensive epidemiologic work but information of considerable public health significance has begun to accumulate. The bulk of the thyroid cancer has been shown to be valid by international pathology review; both EC and WHO representatives have declared the increase in thyroid cancer among children to have been caused in large part by Chernobyl. No increase in leukemia has been seen in the general population. The WHO pilot studies have shown no evidence of an increase in psychologic or neurologic complications among those exposed in utero. Ongoing epidemiologic work can be described by review of the inventory that the WHO has begun to maintain and publish. 20 refs., 7 tabs

    12. Epidemiological Review of Injuries in Rugby Union

      Directory of Open Access Journals (Sweden)

      Jean-François Kaux

      2015-01-01

      Full Text Available Rugby is a sport that is growing in popularity. A contact sport par excellence, it causes a significant number of injuries. In Rugby Union, there are 30 to 91 injuries per 1000 match hours. This epidemiological review of injuries incurred by rugby players mentions the position and type of injuries, the causes, time during the match and season in which they occur and the players’ positions as well as the length of players’ absences following the injury.

    13. [Bad habits and dysgnathia: epidemiological study].

      Science.gov (United States)

      Cordasco, G; Lo Giudice, G; Dolci, E; Romeo, U; Lafronte, G

      1989-01-01

      The authors refer about an epidemiological survey in 651 children in the school-age. The aim of study is to investigate about the frequency of the bad habits and the pathogenetic relations between these and the development of the dento-maxillo-facial deformities. They point out an incidence of these bad habits in the 35,48% with a predominance of mouth breathers (45,45%). After they discuss the necessity of an early detection of anomalous neuromuscular attitudes.

    14. Epidemiology of Postherpetic Neuralgia in Korea

      Science.gov (United States)

      Hong, Myong-Joo; Kim, Yeon-Dong; Cheong, Yong-Kwan; Park, Seon-Jeong; Choi, Seung-Won; Hong, Hyon-Joo

      2016-01-01

      Abstract Postherpetic neuralgia (PHN) is a disease entity defined as persistent pain after the acute pain of herpes zoster gradually resolves. It is associated with impaired daily activities, resulting in reduced quality of life. General epidemiological data on PHN is necessary for the effective management. However, data on the epidemiology of PHN in Korea is lacking. The aim of this study was to evaluate the epidemiological features of PHN in the general population. We used population-based medical data for 51,448,491 subscribers to the Health Insurance Service in the year of 2013 to analyze of PHN epidemiology in Korea, such as the incidence, regional distribution, seasonal variation, and healthcare resource utilization. Total number of patients and medical cost on PHN were analyzed from 2009 to 2013. Findings indicate that the incidence of PHN in Korea was 2.5 per 1000 person-years, which was strongly correlated with age and sex. There were no differences in seasonal variation or regional distribution. The medical cost increased steadily over the study period. When admitted to general hospitals, patients with PHN were mainly managed in the dermatology and anesthesiology departments. The incidence and prevalence rates of PHN in Koreans appear to be considerably higher compared to those in western populations, while the sex and age predisposition was similar. Considering that the pain associated with PHN can have a marked impact on a patient's quality of life resulting in a medicosocial economic burden, anesthesiology physicians have an important role in primary care in Korea. Future research on the cost-effectiveness of the management of PHN is needed. PMID:27057902

    15. The epidemiology of tuberculosis in recent years:

      Directory of Open Access Journals (Sweden)

      Maliheh Metanat

      2012-02-01

      Full Text Available Background: Tuberculosis (TB is one of the most important health issues in developing countries. Understanding the epidemiology of tuberculosis is critical for effective disease control. The global burden of tuberculosis, risk factors for transmission, and the epidemiology of tuberculosis will be reviewed in this article.Materials and Method: We used Scopus, Embase, PubMed, World Health Organization (WHO and scientific Iranian journals from 2000 to 2011; and the last reports from Iranian ministry of health, for extracting data. Key words such as tuberculosis, epidemiology, Iran and Sistan- Balouchestan were used.Results: Descending trend of TB incidence was observed over the last 45 years in Iran. Pulmonary TB is the most prevalent kind of TB in Iran in which 53% were sputum smear positive. Extra-pulmonary TB consists 28% of TB patients. Sistan-Balouchestan and Golestan had the highest incidence and prevalence of TB among all provinces in Iran. According to the latest data from Iranian ministry of health, the incidence of TB in Zabol and Zahedan were reported 109.7 and 36.6 per 100000 populations, respectively. Conclusion: More than 80% of TB patients still belong to developing countries. Sistan-Balouchestan and Golestan had the highest incidence of TB and for achieving the goals of WHO, control and prevention of the disease should be followed seriously

    16. Savannah River Site 1996 epidemiologic surveillance report

      International Nuclear Information System (INIS)

      2000-01-01

      This report provides a summary of epidemiologic surveillance data collected from Savannah River Site from January 1, 1996 through December 31, 1996. The data were collected by a coordinator at Savannah River Site and submitted to the Epidemiologic Surveillance Data Center located at Oak Ridge Institute for Science and Education, where quality control procedures and preliminary data analyses were carried out. The analyses were interpreted and the final report prepared by the DOE Office of Epidemiologic Studies. The information in this report provides highlights of the data analyses conducted on the 1996 data collected from Savannah River Site. The main sections of the report include: work force characteristics; absences due to injury or illness lasting 5 or more consecutive workdays; workplace illnesses, injuries, and deaths that were reportable to the Occupational Safety and Health Administration (''OSHA-recordable'' events); and disabilities and deaths among current workers. The 1996 report includes a new section on time trends that provides comparative information on the health of the work force from 1994 through 1996

    17. Toward systems epidemiology of coffee and health.

      Science.gov (United States)

      Cornelis, Marilyn C

      2015-02-01

      Coffee is one of the most widely consumed beverages in the world and has been associated with many health conditions. This review examines the limitations of the classic epidemiological approach to studies of coffee and health, and describes the progress in systems epidemiology of coffee and its correlated constituent, caffeine. Implications and applications of this growing body of knowledge are also discussed. Population-based metabolomic studies of coffee replicate coffee-metabolite correlations observed in clinical settings but have also identified novel metabolites of coffee response, such as specific sphingomyelin derivatives and acylcarnitines. Genome-wide analyses of self-reported coffee and caffeine intake and serum levels of caffeine support an overwhelming role for caffeine in modulating the coffee consumption behavior. Interindividual variation in the physiological exposure or response to any of the many chemicals present in coffee may alter the persistence and magnitude of their effects. It is thus imperative that future studies of coffee and health account for this variation. Systems epidemiological approaches promise to inform causality, parse the constituents of coffee responsible for health effects, and identify the subgroups most likely to benefit from increasing or decreasing coffee consumption.

    18. Gastric cancer: epidemiology, prevention, classification, and treatment

      Directory of Open Access Journals (Sweden)

      Sitarz R

      2018-02-01

      Full Text Available Robert Sitarz,1–3 Małgorzata Skierucha,1,2 Jerzy Mielko,1 G Johan A Offerhaus,3 Ryszard Maciejewski,2 Wojciech P Polkowski1 1Department of Surgical Oncology, Medical University of Lublin, Lublin, Poland; 2Department of Human Anatomy, Medical University of Lublin, Lublin, Poland; 3Department of Pathology, University Medical Centre, Utrecht, The Netherlands Abstract: Gastric cancer is the second most common cause of cancer-related deaths in the world, the epidemiology of which has changed within last decades. A trend of steady decline in gastric cancer incidence rates is the effect of the increased standards of hygiene, conscious nutrition, and Helicobacter pylori eradication, which together constitute primary prevention. Avoidance of gastric cancer remains a priority. However, patients with higher risk should be screened for early detection and chemoprevention. Surgical resection enhanced by standardized lymphadenectomy remains the gold standard in gastric cancer therapy. This review briefly summarizes the most important aspects of gastric cancers, which include epidemiology, risk factors, classification, diagnosis, prevention, and treatment. The paper is mostly addressed to physicians who are interested in updating the state of art concerning gastric carcinoma from easily accessible and credible source. Keywords: gastric cancer, epidemiology, classification, risk factors, treatment

    19. Epidemiology of Uterine Myomas: A Review

      Directory of Open Access Journals (Sweden)

      Radmila Sparic

      2016-12-01

      Full Text Available Myomas are the most common benign tumors of the genital organs in women of childbearing age, causing significant morbidity and impairing their quality of life. In our investigation, we have reviewed the epidemiological data related to the development of myomas in order to homogenize the current data. Therefore, a MEDLINE and PubMed search, for the years 1990-2013, was conducted using a combination of keywords, such as "myoma," "leiomyoma," "fibroids," "myomectomy," "lifestyle," "cigarette," "alcohol," "vitamins," "diet," and "hysterectomy". Randomized controlled studies were selected based upon the authors’ estimation. Peer-reviewed articles examining myomas were sorted by their relevance and included in this research. Additional articles were also identified from the references of the retrieved papers and included according to authors’ estimation. Many epidemiologic factors are linked to the development of myomas; however, many are not yet fully understood. These factors include age, race, heritage, reproductive factors, sex hormones, obesity, lifestyle (diet, caffeine and alcohol consumption, smoking, physical activity and stress, environmental and other influences, such as hypertension and infection. Some of the epidemiological data is conflicting. Thus, more research is needed to understand all the risk factors that contribute to myoma formation and how they exactly influence their onset and growth.

    20. Acute kidney injury: definition, epidemiology, and outcome.

      Science.gov (United States)

      Srisawat, Nattachai; Kellum, John A

      2011-12-01

      Acute kidney injury (AKI) is a common clinical syndrome whose definition has standardized as a result of consensus by leading experts around the world. As a result of these definitions, reported AKI incidences can now be compared across different populations and settings. Evidence from population-based studies suggests that AKI is nearly as common as myocardial infarction, at least in the western world. This review aims to highlight the recent advances in AKI epidemiology as well as to suggest future directions for prevention and management. This review will focus on the recent studies exploring the AKI epidemiology in and outside the ICU. In particular, the risk of AKI in less severe sepsis is notable as is evidence linking AKI to chronic kidney disease. New emphasis on renal recovery is shaping current thinking as is the use and utility of new biomarkers. This article reviews the recent information about the definition, classification, and epidemiology of AKI. Although new biomarkers are being developed, the 'tried and true' markers of serum creatinine and urine output, disciplined by current criteria, will be important components in the definition and classification of AKI for some time to come.

    1. Chancroid epidemiology in New Orleans men.

      Science.gov (United States)

      DiCarlo, R P; Armentor, B S; Martin, D H

      1995-08-01

      Epidemiologic, clinical, and microbiologic data were collected from 299 men with nonsyphilitic genital ulcer disease. One hundred eighteen (39%) were culture-positive for Haemophilus ducreyi, 57 (19%) were culture-positive for herpes simplex virus, and 124 (41%) were culture-negative. Patients with chancroid were significantly more likely than those with genital herpes to have been frequent users of alcohol (44% vs. 23%, P = .006). They were also more likely recently to have used cocaine (25% vs. 9%, P = .013), had sex with a prostitute (17% vs. 5%, P = .035), traded drugs for sex (16% vs. 2%, P = .005), and had a sex partner who used drugs (38% vs. 13%, P = .001). Culture-negative patients were similar to chancroid patients with respect to most epidemiologic risk factors. Despite the epidemiologic similarities, the clinical features of culture-negative ulcers resembled those of culture-proven herpes ulcers more closely than they did those of culture-proven chancroid ulcers. These data establish a link between chancroid in the United States and the use of crack cocaine.

    2. Molecular epidemiology: new rules for new tools?

      Science.gov (United States)

      Merlo, Domenico Franco; Sormani, Maria Pia; Bruzzi, Paolo

      2006-08-30

      Molecular epidemiology combines biological markers and epidemiological observations in the study of the environmental and genetic determinants of cancer and other diseases. The potential advantages associated with biomarkers are manifold and include: (a) increased sensitivity and specificity to carcinogenic exposures; (b) more precise evaluation of the interplay between genetic and environmental determinants of cancer; (c) earlier detection of carcinogenic effects of exposure; (d) characterization of disease subtypes-etiologies patterns; (e) evaluation of primary prevention measures. These, in turn, may translate into better tools for etiologic research, individual risk assessment, and, ultimately, primary and secondary prevention. An area that has not received sufficient attention concerns the validation of these biomarkers as surrogate endpoints for cancer risk. Validation of a candidate biomarker's surrogacy is the demonstration that it possesses the properties required for its use as a substitute for a true endpoint. The principles underlying the validation process underwent remarkable developments and discussion in therapeutic research. However, the challenges posed by the application of these principles to epidemiological research, where the basic tool for this validation (i.e., the randomized study) is seldom possible, have not been thoroughly explored. The validation process of surrogacy must be applied rigorously to intermediate biomarkers of cancer risk before using them as risk predictors at the individual as well as at the population level.

    3. Epidemiological data and radiation risk estimates

      International Nuclear Information System (INIS)

      Cardis, E.

      2002-01-01

      The results of several major epidemiology studies on populations with particular exposure to ionizing radiation should become available during the first years of the 21. century. These studies are expected to provide answers to a number of questions concerning public health and radiation protection. Most of the populations concerned were accidentally exposed to radiation in ex-USSR or elsewhere or in a nuclear industrial context. The results will complete and test information on risk coming from studies among survivors of the Hiroshima and Nagasaki atomic bombs, particularly studies on the effects of low dose exposure and prolonged low-dose exposure, of different types of radiation, and environmental and host-related factors which could modify the risk of radiation-induced effects. These studies are thus important to assess the currently accepted scientific evidence on radiation protection for workers and the general population. In addition, supplementary information on radiation protection could be provided by formal comparisons and analyses combining data from populations with different types of exposure. Finally, in order to provide pertinent information for public health and radiation protection, future epidemiology studies should be targeted and designed to answer specific questions, concerning, for example, the risk for specific populations (children, patients, people with genetic predisposition). An integrated approach, combining epidemiology and studies on the mechanisms of radiation induction should provide particularly pertinent information. (author)

    4. Savannah River Site 1997 epidemiologic surveillance report

      International Nuclear Information System (INIS)

      2000-01-01

      This report provides a summary of epidemiologic surveillance data collected from Savannah River Site from January 1, 1997 through December 31, 1997. The data were collected by a coordinator at Savannah River Site and submitted to the Epidemiologic Surveillance Data Center located at Oak Ridge Institute for Science and Education, where quality control procedures and preliminary data analyses were carried out. The analyses were interpreted and the final report prepared by the DOE Office of Epidemiologic Studies. The information in this report provides highlights of the data analyses conducted on the 1997 data collected from Savannah River Site. The main sections of the report include: work force characteristics; absences due to injury or illness lasting 5 or more consecutive workdays; workplace illnesses, injuries, and deaths that were reportable to the Occupational Safety and Health Administration (''OSHA-recordable'' events); and disabilities and deaths among current workers. The 199 7 report includes a section on time trends that provides comparative information on the health of the work force from 1994 through 1997

    5. Methodologic assessment of radiation epidemiology studies

      International Nuclear Information System (INIS)

      Beebe, G.W.

      1983-01-01

      Epidemiologic studies of the late effects of ionizing radiation have utilized the entire spectrum of situations in which man has been exposed. These studies have provided insights into the dependence of human effects upon not only dose to target tissues but also other dimensions of exposure, host characteristics, and time following exposure. Over the past three decades studies have progressed from the mere identification of effects to their measurement. Because investigators of human effects have no control over the exposure situation, validity must be sought in the consistency of findings among independent studies and with accepted biologic principles. Because exposure may be confounded with factors that are hidden from view, bias may enter into any study of human exposure. Avoidance of bias and attainment of sufficient power to detect relationships that are real are methodologic challenges. Many methodologic issues, e.g., those associated with the definition and measurement of specific end-points, or with the selection of appropriate controls, permeate epidemiologic work in all fields. Others, especially those concerned with the measurement of exposure, the patterning of events in time after exposure, and the prediction of events beyond the scope of existing observations give radiation epidemiology its distinctive character

    6. The Training of Epidemiologists and Diversity in Epidemiology: Findings from the 2006 Congress of Epidemiology Survey

      Science.gov (United States)

      Carter-Pokras, Olivia D.; Spirtas, Robert; Bethune, Lisa; Mays, Vickie; Freeman, Vincent L.; Cozier, Yvette C.

      2013-01-01

      Purpose In the past decade, we have witnessed increasing numbers of individuals entering the field of epidemiology. With the increase also has come a diversity of training and paths by which individuals entered the field. The purpose of this survey was characterization of the epidemiology workforce, its job diversity, and continuing education needs. Methods The Minority Affairs and Membership committees of the American College of Epidemiology (ACE) prepared and administered a workforce survey to identify racial/ethnic diversity, demographic background, workplace type, credentials, income, subspecialties, and continuing education needs of epidemiologists. The survey was self-administered to attendees of the Second North American Congress of Epidemiology in June 2006. Results A sample of 397 respondents of the 1348 registered for the Congress was captured (29.5% response). Epidemiologists who participated were from 36 states and 18 countries; 54.6% were trained at the doctoral level; 19.1% earned $120,001 or more a year. A wide range of epidemiology subspecialties and continuing education needs were identified. Conclusions This preliminary snapshot of epidemiologists indicates a wide range of training mechanisms, workplace sites, and subspecialties. Results indicate a need for examination of the core graduate training needs of epidemiologist as well as responding to desired professional development needs through the provision of continuing educations efforts. PMID:19344867

    7. Investigación cualitativa y cuantitativa en epidemiología social: ¿es simplemente una cuestión de complementariedad? Qualitative and quantitative research in social epidemiology: is complementarity the only issue?

      Directory of Open Access Journals (Sweden)

      M.B. Gómez

      2003-01-01

      Full Text Available A pesar de que en los últimos años hemos asistido a una creciente aceptación de la investigación cualitativa en el campo de la epidemiología social, el papel y el ámbito de su utilización continúa siendo un campo de debate. En este trabajo presentamos algunos de los temas que han sido el centro del debate entre los investigadores a favor y en contra de la metodología cualitativa para la investigación en epidemiología social y disciplinas relacionadas de la salud pública. Entre los puntos de controversia hay problemas epistemológicos, como las limitaciones de la investigación mediante encuestas para abordar mecanismos sociales, la ausencia de un marco conceptual en los epidemiólogos para generar hipótesis relevantes para poblaciones específicas, y problemas ontológicos como el idealismo inherente a la investigación cualitativa proveniente de la antropología. Se revisan a continuación las etnografías urbanas de Elliot Liebow y una década de investigación en población afroamericana y barrios desfavorecidos en los Estados Unidos para exponer otro papel de la investigación cualitativa en epidemiología social. Así, sostenemos que la investigación cualitativa se ha utilizado en debates científicos en los que se confrontan investigadores igualitaristas con instituciones u otros investigadores con intereses económicos e ideologías opuestas. A menudo la investigación cualitativa es una potente herramienta para apoyar medidas y marcos teóricos alternativos que puedan ser incluidos en estudios poblacionales cuantitativos. Creemos que este uso de la investigación cualitativa se limita al mundo académico sin que necesariamente implique que la comunidad se pueda beneficiar de ella como sucede en el caso de la investigación para la acción.Although in recent years there has been a growing acceptance of qualitative research in social epidemiology, the role and scope of its use remain a contested terrain. We sketch some of the

    8. Bases para proyectiles dirigidos

      Directory of Open Access Journals (Sweden)

      Editorial, Equipo

      1959-03-01

      Full Text Available Aunque actualmente no se ha llegado a una línea general de métodos o sistemas que gobiernen un tipo característico de rampa y servicios auxiliares necesarios para el lanzamiento al espacio de proyectiles dirigidos a grandes alturas y distancias, las experiencias obtenidas en diferentes ensayos, utilizando distintos tipos de proyectiles y trayectorias balísticas, han sentado toda una serie de procedimientos, datos y conclusiones de gran valor balístico que, aun teniendo en cuenta la continua evolución del proyectil, sus formas, combustibles y alcances, se conocen ya, con bastante aproximación, las condiciones mínimas que ha de reunir una base dedicada a este tipo de lanzamientos.

    9. Registrar para avanzar

      Directory of Open Access Journals (Sweden)

      Laia Matarranz Torres

      2017-06-01

      Full Text Available El farmacéutico comunitario es un profesional sanitario con un enorme potencial para mejorar no solo el uso de los medicamentos (detectando, por ejemplo, resultados negativos de la medicación, sino también la prevención de enfermedades y la promoción de la salud pública. Sin duda, el desarrollo y el impulso que están teniendo los servicios profesionales farmacéuticos (SPF desde hace años pueden contribuir decisivamente a que este potencial se consolide de una forma definitiva, obteniendo el reconocimiento del conjunto del sistema sanitario, incluyendo tanto a otros profesionales de la salud (médicos, enfermería, medicina especializada… como a la Administración y, por supuesto, a los propios pacientes beneficiarios de estos servicios. Es cierto que la figura del farmacéutico y su ejercicio sanitario han estado tradicionalmente bien considerados por la población, pero no es menos verdad que la integración de la actividad asistencial de la farmacia comunitaria en el Sistema Nacional de Salud (SNS es, cuanto menos mejorable, y que, incluso, algunas manifestaciones ponen en entredicho de vez en cuando la labor científico-asistencial de las farmacias o generan dudas sobre su capacidad para formar parte de pleno derecho de los equipos de salud que deben trabajar de forma coordinado en la mejora de la atención sanitaria de los pacientes.

    10. Herpes zoster: Epidemiología y clínica Clinical and epidemiological aspects of Herpes zoster

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      Claudia Vujacich

      2008-04-01

      Full Text Available El herpes zoster (HZ constituye una enfermedad de distribución mundial; sin embargo, existen es casos datos comunicados sobre la misma en países de Latinoamérica. Con el objetivo de evaluar aspectos clínicos y epidemiológicos de esta enfermedad en nuestra población, realizamos un análisis retrospectivo de historias clínicas de un centro privado de referencia en enfermedades infecciosas en Buenos Aires, Argentina (período: 2000-2005. Se realizó un análisis estadístico univariado para evaluar los factores asociados a neuralgia posherpética en este grupo de pacientes. Sobre un total de 302 casos evaluables, el 62% correspondieron a mujeres. La mediana de edad fue de 57 años. El 16.1% de los pacientes presentó condiciones predisponentes al desarrollo de zoster. Las localizaciones más frecuentes fueron la torácica, oftálmica y lumbosacra. El 7.75% presentó compromiso de más de dos metámeras. El 94% de los pacientes recibió medicación antiviral, siendo el aciclovir la droga más utilizada. El 94% recibió alguna medicación coadyuvante (antiinflamatorios no esteroideos, antineuríticos, corticoides. La complicación más frecuente fue la neuralgia posherpética (12% y se encontró estadísticamente asociada a edad mayor de 50 años.Herpes zoster (HZ is a public health problem worldwide. Although, there is paucity of data of this disease from South American countries. The objective of this study was to evaluate clinical and epidemiological aspects of HZ in a population of patients from South America. We underwent a retrospective analysis of clinical charts of an infectious diseases reference center (period: 2000-2005. Univariate analysis was performed to assess variables related to post herpetic neuralgia (PHN. From a total of 302 cases, 62% were in women. The median age was 57 years; 16.1% of the patients had a predisposing condition for the development of HZ. Most frequent dermatomes involved were: thoracic, ophthalmic and

    11. Evaluación de las políticas contra el tabaquismo en países latinoamericanos en la era del Convenio Marco para el Control del Tabaco Evaluating tobacco control policy in Latin American countries during the era of the Framework Convention on Tobacco Control

      Directory of Open Access Journals (Sweden)

      James Francis Thrasher

      2006-01-01

      Full Text Available OBJETIVO: El Convenio Marco para el Control del Tabaco (CMCT pretende coordinar las políticas mundiales que reducen el consumo de tabaco. Con toda probabilidad, estas medidas tendrán efectos en países de ingresos medianos y bajos; no obstante, se requieren estudios de evaluación para determinar sus consecuencias y las posibles sinergias entre las directrices. MATERIAL Y MÉTODOS: El Proyecto Internacional de Evaluación de Políticas para el Control del Tabaco (ITC es una colaboración internacional para evaluar el efecto psicosocial y conductual que causan las políticas promovidas por el CMCT en adultos fumadores de nueve países. El marco de evaluación ITC utiliza diversos controles de país, con un diseño longitudinal y un modelo conceptual basado en teorías para probar las hipótesis sobre los efectos anticipados de determinadas políticas. RESULTADOS: Los resultados del análisis de datos confirman por lo general los hallazgos anteriores de investigaciones basadas en las recomendaciones del CMCT, y se refieren a las siguientes políticas: promover etiquetas de advertencia con imágenes gráficas, prohibir el uso de las descripciones "ligero" y "suave", establecer ambientes libres de humo de tabaco, incrementar los impuestos, prohibir la publicidad del cigarro e implementar nuevos métodos para evaluar los componentes del cigarro. CONCLUSIONES: Los hallazgos iniciales sugieren que los países latinoamericanos podrían aplicar métodos similares para vigilar y evaluar sus propias directrices, así como fortalecer el cuerpo de conocimiento sobre políticas en otros países.OBJECTIVE: The Framework Convention on Tobacco Control (FCTC aims to coordinate tobacco control policies around the world that reduce tobacco consumption. The FCTC's recommended policies are likely to be effective in low- and middle-income countries. Nevertheless, policy evaluation studies are needed to determine policy impact and potential synergies across policies

    12. Respaldo de la reglamentación farmacéutica cubana para la intercambiabilidad terapéutica de los medicamentos genéricos

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      Celeste Aurora Sánchez González

      2004-04-01

      Full Text Available Se realizó una caracterización de la Reglamentación Farmacéutica Cubana durante los últimos 24 años, a partir del enfoque internacional sobre los requerimientos de respaldo para la intercambiabilidad terapéutica de los medicamentos genéricos o de múltiples fuentes. Se relacionaron las normativas emitidas sobre prácticas adecuadas de fabricación y control de calidad para medicamentos y para las inspecciones como vía para implementar su cumplimiento; del registro de medicamentos como instrumento sanitario del control de la comercialización en el que son evaluadas las características del producto farmacéutico en función del cumplimiento de los estándares vigentes para demostrar su calidad, seguridad y eficacia. Fueron identificadas las regulaciones a cumplimentar para la rotulación e información de los medicamentos y en particular los lineamientos para la demostración de intercambiabilidad terapéutica y bioequivalencia, en su condición de guías específicas para los genéricos. Fueron incluidos los niveles institucionales de las autoridades de salud nacionales de los instrumentos legales para las directrices y las acciones reglamentarias que amparan de forma general la equivalencia y sustitución clínica de los productos farmacéuticos multiorigen. Se concluyó el satisfactorio nivel normativo alcanzado y se mostró una figura con el resumen cuantitativo de eventos reguladores en el tiempo que evidencian la plataforma de aseguramiento para la intercambiabilidad terapéutica de los genéricos en nuestro país.A characterization of the Cuban Pharmaceutical Regulation during the last 24 years was made, starting from the international approach on the supporting requirements for the theapeutical interchangeability of generic drugs or of multiple sources. The standards established on the adequate manufacturing practices and quality control for drugs and for inspections as a way to check their fulfillment, on the registry of drugs

    13. The para-petroleum industry

      International Nuclear Information System (INIS)

      2002-07-01

      The para-petroleum industry includes societies that realize studies and installations for the deposits exploitation. This document presents the situation of the para-petroleum industry in 2001, the world investment growth of the activity, the french societies financial results and an inventory of the main operations in the amalgamation domain. (A.L.B.)

    14. Ética e epidemiologia Ethics and epidemiology

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      Rita Barradas Barata

      2005-12-01

      Full Text Available As ações humanas acontecem na confluência de circunstâncias em meio às quais é preciso discernir o modo correto de agir. A ética situa-se no campo do saber prático, do conhecimento acerca do que é contingente. A ética é do domínio dos juízos morais ou juízos de valor. O desencantamento do mundo contemporâneo tem sua contrapartida no esforço para recompor o interesse pela ética. As relações entre saúde pública e direitos humanos são principalmente de três ordens: a busca do equilíbrio entre o bem coletivo e os direitos individuais; os métodos e técnicas para identificar as violações aos direitos humanos e avaliar seu impacto negativo; e, a vinculação entre proteção dos direitos humanos e promoção da saúde. As relações entre ética e epidemiologia vão além dos aspectos éticos relacionados à pesquisa em seres humanos. Desdobram-se em compromissos políticos, práticas nos serviços de saúde e produção de conhecimentos.Human actions take place at the confluence of circumstances that require us to discern the proper way to act. Ethics falls within the terrain of practical knowledge, of knowledge about what is contingent. It belongs to the domain of moral judgments or value judgments. The counterpart of disenchantment with our contemporary world lies in an effort to re-establish an interest in ethics. There are basically three orders of relations between public health and human rights: the quest for balance between the collective good and individual rights; methods and techniques for identifying human rights violations and assessing their negative impact; and the tie between protecting individual rights and promoting health. The relationship between ethics and epidemiology goes beyond the ethical aspects involving research on human beings to encompass political commitments, practices within health services, and the production of knowledge.

    15. Radiation epidemiology: concept, methodology and statistical resources

      International Nuclear Information System (INIS)

      Vasques, Monica H. Braga; Carneiro, Janete C. Gaburo; Sordi, Gian M.A.

      2008-01-01

      As radiation exposure is the main point of interest in radiation epidemiology, epidemiologists try to relate the risk of diseases (mainly the risk of cancer) to the different levels and patterns of humankind exposure to radiation. Statistics as a branch of mathematics is able to prove associations and infer causality. As many researches are object of methodological limits, mainly those related to both the insufficient size of the sample and descriptive analysis as well as the choice of methods and variables, this paper aims at describing firstly the main kinds of epidemiological studies. Secondly, it relates distributions and summary measures (central tendency measures, measures of dispersion and normal distributions) and hypothesis tests as well necessary for each study. It also discusses the most appropriate statistical resource to the epidemiological evaluation. Finally, the main aim of this study is both to elaborate a systematic review of the researches that have been already done in Brazil since 2000, focusing on the effects caused by the occupational exposures to ionizing radiation in order to establish positive associations between them and to analyze the risk related to the workers health. This paper has as its basis the Reports in Public Health (Public Health Books-CSP) from which several studies about the exposure effects to ionizing radiation and referred kinds of cancer (e.g.: leukemia, skin cancer, thyroid gland cancer and bone cancer) have been taken as object of analysis. The relevance of this study lies in the most applied methods of risk to establish positive associations in ionizing radiation, in the relation between workers' workplace and his health. (author)

    16. Epidemiology of Dermatophytoses in Crete, Greece.

      Science.gov (United States)

      Maraki, Sofia; Mavromanolaki, Viktoria Eirini

      2016-01-01

      Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world. A total of 2,910 clinical specimens (skin scrapings, nail clippings, and hair specimens) obtained from 2,751 patients with signs of dermatomycoses were examined using direct microscopy and culture. Overall, 294 specimens (10.1%) were proved mycologically positive for dermatophytes. The age of the patients ranged from 2 to 86 years (mean age, 37 years). Tinea corporis was the predominant clinical type of infection, followed by tinea unguium, tinea pedis, tinea capitis, tinea faciei, tinea cruris and tinea manuum. Among dermatophytes, eight species were isolated: Microsporum canis (35.8%), Trichophyton rubrum (35.1%), Trichophyton mentagrophytes (23.3%), Epidermophyton floccosum (2.5%), Microsporum gypseum (1.8%), Trichophyton violaceum (0.7%), Trichophyton verrucosum (0.4%), and Trichophyton tonsurans (0.4%). In our area, the most common dermatophyte was M. canis followed by T. rubrum. Increased migration, mass tourism, and climate changes will contribute to further changes in the epidemiology of dermatophytoses in our area. Continuing studies are necessary for determining the new epidemiological trends and to implement the appropriate control measures.

    17. Injury epidemiology in Iran: a systematic review

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      Saber Azami-Aghdash

      2017-01-01

      Full Text Available Background: Injuries are the second greatest cause of mortality in Iran. Information about the epidemiological pattern of injuries is effective in decision-making. In this regard, the aim of the current study is to elaborate on the epidemiology of injuries in Iran through a systematic review. Methods: Required data were collected searching the following key words and their Persian equivalents; trauma, injury, accident, epidemiology, prevalence, Pattern, etiology, risk factors and Iran. The following databases were searched: Google Scholar, PubMed, Scopus, MagIran, Iranian scientific information database (SID and Iran Medex. Some of the relevant journals and web sites were searched manually. The lists of references from the selected articles were also investigated. We have also searched the gray literature and consulted some experts. Results: Out of 2747 retrieved articles, 25 articles were finally included in the review. A total of 3234481 cases have been investigated. Mean (SD age among these cases was 30 (17.4 years. Males comprised 75.7% of all the patients. Only 31.1% of patients were transferred to hospital by ambulance. The most common mechanism of injuries was road traffic accidents (50.1%, followed by falls (22.3%. In road traffic accidents, motorcyclists have accounted for the majority of victims (45%. Roads were the most common accident scene for the injuries (57.5%. The most common injuries were to the head and neck. (47.3%. The mean (SD Injury Severity Score (ISS was 8.1(8.6%. The overall case-fatality proportion was 3.8% and 75% of all the mortalities related to road traffic accidents. Conclusions: The main priorities in reducing the burden of injuries include: the young, male target group, improving pre-hospital and ambulance services, preventing road traffic accidents, improving road safety and the safety of motorcyclists (compulsory helmet use, safer vehicles, dedicated motorcycle lanes.

    18. Benchcolombia, sistema de referenciación para la construcción

      Directory of Open Access Journals (Sweden)

      Luis Fernando Botero

      2007-05-01

      Full Text Available A pesar de algunos esfuerzos aislados realizados en varias empresas constructoras colombianas, con el fin de medir el desempeño de sus proyectos, no existe en Colombia actualmente una metodología unificada que permita recoger, analizar y comparar los resultados obtenidos, mediante una herramienta práctica; la cual suministre los medios apropiados para la referenciación, facilite el mejoramiento continuo del sector de la construcción y genere aprendizaje de buenas prácticas de gestión. Partiendo de la experiencia en la implementación de los principios de Lean Construction (construcción sin pérdidas, llevada a cabo durante los tres últimos años en las ciudades de Medellín, Bogotá y Manizales, con apropiación de los nuevos conceptos en gestión de la producción enfocada a la construcción y a la generación de una cultura de la medición, un grupo de importantes empresas de la ciudad de Medellín -convocadas por CIDICO (Centro de investigación y desarrollo tecnológico para la industria de la construcción, con la iniciativa de GESCÓN (grupo de investigación en gestión de la construcción, Universidad EAFIT y la cofinanciación del SENA (Servicio Nacional de Aprendizaje- se ha propuesto desarrollar e implementar un sistema de referenciación para el sector de la construcción, que permita la comparación del desempeño integral del proyecto de construcción a nivel local, nacional e internacional, pues se comparten los principios y directrices de los sistemas de referenciación establecidos con anterioridad en EEUU, Reino Unido, Chile y Brasil./ Despite the efforts that some Colombian building companies have made in order to measure the performance of their projects, there is not at this moment a unified methodology to gather, analyze, and compare the results of such projects in the country. Consequently, a practical tool to do Benchmarking, may facilitate the continuous improvement of the construction industry, and generate

    19. Social phobia: epidemiology and health care.

      Science.gov (United States)

      Wancata, Johannes; Fridl, Marion; Friedrich, Fabian

      2009-12-01

      This paper gives an overview on the epidemiology of social phobia. About 4.5% of the adult general populations suffer from social phobia, i.e. it is the most frequent of all anxiety disorders. Social phobia is clearly more frequent among women than among men. About the half of all individuals with social phobia suffer from any comorbid mental disorders. Reviews show a large variability between single studies, probably due to methodological differences. Several population surveys indicate that a marked proportion of those with social phobia do not receive adequate treatment.

    20. Epidemiology of selected gynaecological malignancies in Slovakia

      International Nuclear Information System (INIS)

      Ondrusova, M.; Psenkova, M.; Sadovsky, O.

      2015-01-01

      The study analyses selected trends of descriptive epidemiology of ovarian cancer, endometrial cancer and cervical cancer in Slovakia point to time trends in their development, enabling a prediction of the development of the indicators in the years to come. Based on the results of analyses, it was discovered that the incidence of ovarian cancer and endometrial cancer in women in Slovakia is rising continually and significantly, while mortality in both diagnoses is declining. In respect of cervical cancer, a stabilised trend in incidence was registered, with an important, but very mild drop in mortality values. (author)

    1. Comprehensive Epidemiologic Data Resource. Revision 1

      International Nuclear Information System (INIS)

      1995-05-01

      The Department of Energy has established the Comprehensive Epidemiologic Data Resource (CEDR) as a public-use data base with the goal of broadening independent access to data collected during studies of the health effects of exposure to radiation and other physical or chemical agents associated with the production of nuclear materials. This catalog is intended for use by any individual interested in obtaining information about, or access to, CEDR data. This catalog provides information that will help users identify and request data file sets of interest

    2. Epidemiology and natural history of atopic diseases

      DEFF Research Database (Denmark)

      Thomsen, Simon F

      2015-01-01

      The atopic diseases - atopic dermatitis, asthma, and hay fever - pose a great burden to the individual and society, not least, since these diseases have reached epidemic proportions during the past decades in industrialized and, more recently, in developing countries. Whereas the prevalence...... of the atopic diseases now seems to have reached a plateau in many Western countries, they are still on the increase in the developing world. This emphasizes continuing research aimed at identifying the causes, risk factors, and natural history of these diseases. Herein, the fundamental aspects of the natural...... history and epidemiology of the atopic diseases are reviewed....

    3. Comprehensive Epidemiologic Data Resource. Revision 1

      Energy Technology Data Exchange (ETDEWEB)

      NONE

      1995-05-01

      The Department of Energy has established the Comprehensive Epidemiologic Data Resource (CEDR) as a public-use data base with the goal of broadening independent access to data collected during studies of the health effects of exposure to radiation and other physical or chemical agents associated with the production of nuclear materials. This catalog is intended for use by any individual interested in obtaining information about, or access to, CEDR data. This catalog provides information that will help users identify and request data file sets of interest.

    4. Gastric cancer: epidemiology, prevention, classification, and treatment

      OpenAIRE

      Sitarz, Robert; Skierucha, Małgorzata; Mielko, Jerzy; Offerhaus, G Johan A; Maciejewski, Ryszard; Polkowski, Wojciech P

      2018-01-01

      Robert Sitarz,1–3 Małgorzata Skierucha,1,2 Jerzy Mielko,1 G Johan A Offerhaus,3 Ryszard Maciejewski,2 Wojciech P Polkowski1 1Department of Surgical Oncology, Medical University of Lublin, Lublin, Poland; 2Department of Human Anatomy, Medical University of Lublin, Lublin, Poland; 3Department of Pathology, University Medical Centre, Utrecht, The Netherlands Abstract: Gastric cancer is the second most common cause of cancer-related deaths in the world, the epidemiology of which has ch...

    5. Recommendations for epidemiological studies on COPD

      DEFF Research Database (Denmark)

      Bakke, P S; Rönmark, E; Eagan, T

      2011-01-01

      of the disease and definitions of the risk factors. Few community studies have examined phenotypes of COPD and included other ways of characterising the disease beyond that of spirometry. The objective of the present Task Force report is to present recommendations for the performance of general population...... for planning and performing an epidemiological study on COPD. The main message of the paper is that thorough planning is worth half the study. It is crucial to stick to standardised methods and good quality control during sampling. We recommend collecting biological markers, depending on the specific...

    6. Microbiology and Epidemiology of Legionnaire's Disease.

      Science.gov (United States)

      Burillo, Almudena; Pedro-Botet, María Luisa; Bouza, Emilio

      2017-03-01

      Legionnaire's disease (LD) is the pneumonic form of legionellosis caused by aerobic gram-negative bacilli of the genus Legionella. Individuals become infected when they inhale aerosolized water droplets contaminated with Legionella species. Forty years after the identification of Legionella pneumophila as the cause of the 1976 pneumonia outbreak in a hotel in Philadelphia, we have non-culture-based diagnostic tests, effective antibiotics, and preventive measures to handle LD. With a mortality rate still around 10%, underreporting, and sporadic outbreaks, there is still much work to be done. In this article, the authors review the microbiology, laboratory diagnosis, and epidemiology of LD. Copyright © 2016 Elsevier Inc. All rights reserved.

    7. Epidemiology of falls in older age.

      Science.gov (United States)

      Peel, Nancye May

      2011-03-01

      Worldwide, falls among older people are a public health concern because of their frequency and adverse consequences in terms of morbidity, mortality, and quality of life, as well as their impact on health system services and costs. This epidemiological review outlines the public health burden of falls and fall-related injuries and the impact of population aging. The magnitude of the problem is described in terms of the classification of falls and measurement of outcomes, including fall incidence rates across settings, sociodemographic determinants, international trends, and costs of falls and fall-related injuries. Finally, public health approaches to minimize falls risk and consequent demand on health care resources are suggested.

    8. Epidemiological studies on radiation workers in Korea

      International Nuclear Information System (INIS)

      Soo Yong Choi; Hai Won Chung

      2007-01-01

      Complete text of publication follows. Objectives: The aim of this study is to analyze the occupational exposure for external radiation and to evaluate radiation effects on Korean radiation workers. Methods: The National Dose Registry contains radiation exposure records for all monitored radiation workers since its creation in 1983. We are carrying out epidemiological survey for radiation workers. The items of information included personal identification, employment and dose data. The frequencies of various types of chromosome aberrations in radiation workers were compared with controls. The data were analyzed according to year, sex, age, duration of occupation, exposure dose, etc. using SPSS statistical package(version 15.0). The goodness-of-fit test for Poisson assumption and dispersion test for detecting heterogeneity for Poisson distribution were done with chromosomal aberrations among study subjects. Results: The total number of workers registered from 1983 to 2005 was 61,610. The number of workers steadily increased and the accumulated dose somewhat increased. The collective annual dose of radiation workers was 345.823 man Sv and the mean annual dose was 1.34mSv. The frequencies of chromosome aberrations in 102 workers were compared with those in 42 controls. The frequencies of all types of chromosome aberrations in the exposed subjects were higher than those in the control group. Poisson regression analysis showed that there was significant association of chromosome aberrations with radiation dose, duration of work, age and alcohol intake. We started to survey radiation workers in order to evaluate radiation effects, collected epidemiological data for 9,157 workers at present and analyzed their lifetime radiation exposure doses. Follow-up is carrying out using the Korean Mortality Data, Cancer Registry and individual investigation. Among study patients, 11 of 38 deaths were identified with cancer. Conclusions: The data on occupational doses shows that

    9. Global epidemiology of podoconiosis: A systematic review.

      Science.gov (United States)

      Deribe, Kebede; Cano, Jorge; Trueba, Mei L; Newport, Melanie J; Davey, Gail

      2018-03-01

      Podoconiosis is one of the few diseases that could potentially be eliminated within one generation. Nonetheless, the global distribution of the disease remains largely unknown. The global atlas of podoconiosis was conceived to define the epidemiology and distribution of podoconiosis through dedicated surveys and assembling the available epidemiological data. We have synthesized the published literature on the epidemiology of podoconiosis. Through systematic searches in SCOPUS and MEDLINE from inception to February 14, 2018, we identified observational and population-based studies reporting podoconiosis. To establish existence of podoconiosis, we used case reports and presence data. For a study to be included in the prevalence synthesis, it needed to be a population-based survey that involved all residents within a specific area. Studies that did not report original data were excluded. We undertook descriptive analyses of the extracted data. This study is registered with PROSPERO, number CRD42018084959. We identified 3,260 records, of which 27 studies met the inclusion criteria. Podoconiosis was described to exist or be endemic in 32 countries, 18 from the African Region, 3 from Asia and 11 from Latin America. Overall, podoconiosis prevalence ranged from 0·10% to 8.08%, was highest in the African region, and was substantially higher in adults than in children and adolescents. The highest reported prevalence values were in Africa (8.08% in Cameroon, 7.45% in Ethiopia, 4.52% in Uganda, 3.87% in Kenya and 2.51% in Tanzania). In India, a single prevalence of 0.21% was recorded from Manipur, Mizoram and Rajasthan states. None of the Latin American countries reported prevalence data. Our data suggest that podoconiosis is more widespread in the African Region than in the rest of the regions, although this could be related to the fact that most podoconiosis epidemiological research has been focused in the African continent. The assembled dataset confirms that comprehensive

    10. Global epidemiology of podoconiosis: A systematic review.

      Directory of Open Access Journals (Sweden)

      Kebede Deribe

      2018-03-01

      Full Text Available Podoconiosis is one of the few diseases that could potentially be eliminated within one generation. Nonetheless, the global distribution of the disease remains largely unknown. The global atlas of podoconiosis was conceived to define the epidemiology and distribution of podoconiosis through dedicated surveys and assembling the available epidemiological data.We have synthesized the published literature on the epidemiology of podoconiosis. Through systematic searches in SCOPUS and MEDLINE from inception to February 14, 2018, we identified observational and population-based studies reporting podoconiosis. To establish existence of podoconiosis, we used case reports and presence data. For a study to be included in the prevalence synthesis, it needed to be a population-based survey that involved all residents within a specific area. Studies that did not report original data were excluded. We undertook descriptive analyses of the extracted data. This study is registered with PROSPERO, number CRD42018084959.We identified 3,260 records, of which 27 studies met the inclusion criteria. Podoconiosis was described to exist or be endemic in 32 countries, 18 from the African Region, 3 from Asia and 11 from Latin America. Overall, podoconiosis prevalence ranged from 0·10% to 8.08%, was highest in the African region, and was substantially higher in adults than in children and adolescents. The highest reported prevalence values were in Africa (8.08% in Cameroon, 7.45% in Ethiopia, 4.52% in Uganda, 3.87% in Kenya and 2.51% in Tanzania. In India, a single prevalence of 0.21% was recorded from Manipur, Mizoram and Rajasthan states. None of the Latin American countries reported prevalence data.Our data suggest that podoconiosis is more widespread in the African Region than in the rest of the regions, although this could be related to the fact that most podoconiosis epidemiological research has been focused in the African continent. The assembled dataset confirms

    11. Low doses of radiation: epidemiological investigations

      International Nuclear Information System (INIS)

      Dikiy, N.P.; Dovbnya, A.N.; Medvedeva, E.P.

      2013-01-01

      Influence of small dozes of radiation was investigated with the help epidemiologic evidence. Correlation analysis, regression analysis and frequency analysis were used for investigating morbidity of various cancer illnesses. The pollution of the environment and the fallout of radionuclides in 1962 and 1986 years have an influence upon morbidity of cancer. Influence of small dozes of radiation on health of the population is multifactorial. Therefore depending on other adverse external conditions the influence of radiation in small dozes can be increased or is weakened. Such character of influence of radiation in small dozes proposes the differentiated approach at realization of preventive measures. Especially it concerns regions with favorable ecological conditions.

    12. The Changing Epidemiology of Pediatric Endocarditis.

      Science.gov (United States)

      Elder, Robert W; Baltimore, Robert S

      2015-09-01

      The epidemiology of infective endocarditis (IE) appears to be related to changes in the management of children with congenital heart disease (CHD) and the virtual disappearance of rheumatic heart disease. To better understand these changes, we divide the history into: I. The pre-surgical era, II. The early years of CHD surgical intervention, correlated with introduction of antibiotics, III. The modern era of cardiac interventions. Microbiologic changes include an early predominance of viridans streptococci and an overtaking by staphylococci. Additionally, there have been advances in imaging that allow earlier detection of IE and a reduction in IE-related mortality. Copyright © 2015 Elsevier Inc. All rights reserved.

    13. Thyroid disorders in India: An epidemiological perspective

      Directory of Open Access Journals (Sweden)

      Ambika Gopalakrishnan Unnikrishnan

      2011-01-01

      Full Text Available Thyroid diseases are common worldwide. In India too, there is a significant burden of thyroid diseases. According to a projection from various studies on thyroid disease, it has been estimated that about 42 million people in India suffer from thyroid diseases. This review will focus on the epidemiology of five common thyroid diseases in India: (1 hypothyroidism, (2 hyperthyroidism, (3 goiter and iodine deficiency disorders, (4 Hashimoto′s thyroiditis, and (5 thyroid cancer. This review will also briefly cover the exciting work that is in progress to ascertain the normal reference range of thyroid hormones in India, especially in pregnancy and children.

    14. Smoking, epidemiology and e-cigarettes

      OpenAIRE

      Raschke RA

      2013-01-01

      No abstract available. Article truncated at 150 words. “The true face of smoking is disease, death and horror - not the glamour and sophistication the pushers in the tobacco industry try to portray.” - David Byrne In our fellows’ conference we recently reviewed the evolution of the science of clinical epidemiology as it relates to the association of smoking and lung cancer and the concurrent history of tobacco marketing in the United States. This story begins in 1950, when Richard Doll and A...

    15. Epidemiology of congenital diaphragmatic hernia in Europe

      DEFF Research Database (Denmark)

      McGivern, Mark R.; Best, Kate E.; Rankin, Judith

      2015-01-01

      INTRODUCTION: Published prevalence rates of congenital diaphragmatic hernia (CDH) vary. This study aims to describe the epidemiology of CDH using data from high-quality, population-based registers belonging to the European Surveillance of Congenital Anomalies (EUROCAT). METHODS: Cases of CDH...... for isolated cases (ie, CDH cases that did not occur with any other congenital anomaly). There was significant variation in total and isolated CDH prevalence between registers. The proportion of cases that survived to 1 week was 69.3% (1392 cases) for total CDH cases and 72.7% (1107) for isolated cases...

    16. Epidemiología del tabaquismo en Europa

      Directory of Open Access Journals (Sweden)

      Fernández Esteve

      2002-01-01

      Full Text Available El tabaco es la causa de mortalidad prevenible más importante en los países europeos, en los que da cuenta de más de medio millón de muertes anuales. El objetivo de este trabajo es revisar la epidemiología del tabaquismo en Europa, atendiendo a la visión de conjunto sobre el impacto del tabaquismo, a la prevalencia del consumo y a su evolución en la última década, así como revisar otras características relacionadas con la difusión y mantenimiento del tabaquismo: la producción y los precios del tabaco. Treinta de cada 100 europeos adultos fuma cigarrillos a diario. En los países de la Unión Europea se estima que 1 de cada 10 adultos fumadores morirá a causa de los efectos del tabaco, razón que se eleva a 1 de cada 5 en los países del este de Europa. La prevalencia de fumadores desciende entre los hombres adultos en algunos países de la Unión Europea, mientras que aumenta en las mujeres, sobre todo jóvenes, del sur y del este de Europa. Se debe insistir en las medidas para controlar el consumo de tabaco y prevenirlo, tales como la prohibición del consumo en lugares públicos, la prohibición real de la publicidad directa e indirecta, la reducción del cultivo, o el incremento de precios. Estas acciones se deben diseñar, coordinar y desarrollar en y desde los diferentes sectores involucrados en la lucha contra el tabaco, con la participación de redes civiles impulsadas desde los diferentes niveles administrativos (local, regional, nacional con la decisiva participación de organismos y organizaciones supranacionales.

    17. Descriptive and analytic epidemiology. Bridges to cancer control

      International Nuclear Information System (INIS)

      Mettlin, C.

      1988-01-01

      Epidemiology serves as a bridge between basic science and cancer control. The two major orientations of epidemiology are descriptive and analytic. The former is useful in assessing the scope and dimensions of the cancer problem and the latter is used to assess environmental and lifestyle sources of cancer risk. A recent development in descriptive epidemiology is the use of functional measures of disease such as lost life expectancy. In analytical epidemiology, there is new or renewed interest in several lifestyle factors including diet and exercise as well as environmental factors such as involuntary tobacco exposure and radon in dwellings. Review of the evidence should consider the strengths and weaknesses of different research procedures. Each method is inconclusive by itself but, the different research designs of epidemiology collectively may represent a hierarchy of proof. Although the roles of many factors remain to be defined, the aggregate epidemiologic data continue to demonstrate the special importance of personal behavior and lifestyle in affecting cancer risk

    18. Para-bosons and Para-fermions in Quantum Mechanics

      International Nuclear Information System (INIS)

      Cattani, M.S.D.; Fernandes, N.C.

      1982-01-01

      Within the framework of the ordinary quantum mechanics, a detailed study of the energy eigenfunctions of N identical particles using the irreducible representations of the permutation group in the Hilbert space is performed. It is shown that the para-states, as occurs with the boson and fermion states, are compatible with the postulates of quantum mechanics and with the principle of indistinguishability. A mathematical support for the existence of para-bosons and para-fermions is given. Gentile's quantum statistics is, in a certain sense, justified. (Author) [pt

    19. Generating para-water from para-hydrogen: A Gedankenexperiment.

      Science.gov (United States)

      Ivanov, Konstantin L; Bodenhausen, Geoffrey

      2018-07-01

      A novel conceptual approach is described that is based on the transfer of hyperpolarization from para-hydrogen in view of generating a population imbalance between the two spin isomers of H 2 O. The approach is analogous to SABRE (Signal Amplification By Reversible Exchange) and makes use of the transfer of spin order from para-hydrogen to H 2 O in a hypothetical organometallic complex. The spin order transfer is expected to be most efficient at avoided level crossings. The highest achievable enrichment levels of para- and ortho-water are discussed. Copyright © 2018 Elsevier Inc. All rights reserved.

    20. Ophthalmic epidemiology in Europe : the "European Eye Epidemiology" (E3) consortium

      NARCIS (Netherlands)

      Delcourt, Cecile; Korobelnik, Jean-Francois; Buitendijk, Gabrielle H. S.; Foster, Paul J.; Hammond, Christopher J.; Piermarocchi, Stefano; Peto, Tunde; Jansonius, Nomdo; Mirshahi, Alireza; Hogg, Ruth E.; Bretillon, Lionel; Topouzis, Fotis; Deak, Gabor; Grauslund, Jakob; Broe, Rebecca; Souied, Eric H.; Creuzot-Garcher, Catherine; Sahel, Jose; Daien, Vincent; Lehtimaki, Terho; Hense, Hans-Werner; Prokofyeva, Elena; Oexle, Konrad; Rahi, Jugnoo S.; Cumberland, Phillippa M.; Schmitz-Valckenberg, Steffen; Fauser, Sascha; Bertelsen, Geir; Hoyng, Carel; Bergen, Arthur; Silva, Rufino; Wolf, Sebastian; Lotery, Andrew; Chakravarthy, Usha; Fletcher, Astrid; Klaver, Caroline C. W.

      The European Eye Epidemiology (E3) consortium is a recently formed consortium of 29 groups from 12 European countries. It already comprises 21 population-based studies and 20 other studies (case-control, cases only, randomized trials), providing ophthalmological data on approximately 170,000

    1. Assessment of epidemiological parameters and their use in epidemiological and forecasting models of cereal airborne diseases

      DEFF Research Database (Denmark)

      Vallavieille-Pope, C. de; Giosue, S.; Munk, L.

      2000-01-01

      Assessments of epidemiological parameters (e.g. infection efficiency, latent period, spore production) are required for the prediction of epidemic progress, for the estimation of components of partial resistance for different host plant cultivars and for the estimation of fitness components of pa...

    2. Standard epidemiological methods to understand and improve Apis mellifera health

      OpenAIRE

      Lengerich, Eugene; Spleen, Angela; Dainat, Benjamin; Cresswell, James; Baylis , Kathy; Nguyen, Bach Kim; Soroker, Victoria; Underwood, Robyn; Human, Hannelie; Le Conte, Yves; Saegerman, Claude

      2013-01-01

      In this paper, we describe the use of epidemiological methods to understand and reduce honey bee morbidity and mortality. Essential terms are presented and defined and we also give examples for their use. Defining such terms as disease, population, sensitivity, and specificity, provides a framework for epidemiological comparisons. The term population, in particular, is quite complex for an organism like the honey bee because one can view “epidemiological unit” as individual bees, colonies, ap...

    3. Para compreender a ciberliteratura

      Directory of Open Access Journals (Sweden)

      Lucia Santaella

      2012-12-01

      Full Text Available http://dx.doi.org/10.5007/1807-9288.2012v8n2p229   Mediante as mídias digitais, a configuração da literatura sofreu um salto qualitativo em todos os seus aspectos. O espaço virtual gerado pelas redes de computadores funciona como um novo meio. Abre-se com ele uma miríade de oportunidades que expandem o conceito de literatura em função da emergência de novas formas de criação literária. Disso decorre que a criação, a teoria e a crítica literárias exigem a redefinição de seus paradigmas herdados da era de Gutenberg. Tendo isso em vista, este artigo está voltado para a construção textual e hipertextual no espaço digital, o que implica uma exploração do que é ciberliteratura, em que ela se cruza e em que diverge da literatura impressa, que estratégias significantes a caracterizam e como essas estratégias são interpretadas pelos usuários na sua busca de significado.

    4. para promover la salud

      Directory of Open Access Journals (Sweden)

      Ma. del Consuelo Chapela

      2002-01-01

      Full Text Available Hablar de educación a distancia sustentada en el desarrollo de la cibernética obliga a reflexionar sobre sus definiciones, objetivos y medios, especialmente si pensamos en las necesidades de la fracción de población que no tiene acceso a las posibilidades que ofrece el desarrollo tecnológico. En este trabajo se presenta e ilustra con un ejemplo práctico, una perspectiva sobre las posibilidades de la educación a distancia desde las necesidades de la promoción de la salud entre grupos de población marginada en el mundo virtual. Se propone la creación de bibliotecas itinerantes regionales que pongan a disposición de la población con acceso limitado a la información, la tecnología comunicativa necesaria para apoyar los trabajos de promoción de la salud.

    5. Determinação de escore e nota de corte do módulo de asma do International Study of Asthma and Allergies in Childhood para discriminação de adultos asmáticos em estudos epidemiológicos Determining the score and cut-off point that would identify asthmatic adults in epidemiological studies using the asthma module of the International Study of Asthma and Allergies in Childhood questionnaire

      Directory of Open Access Journals (Sweden)

      Elayne de Fátima Maçãira

      2005-12-01

      Full Text Available OBJETIVO: Validar o questionário padronizado escrito do International Study of Asthma and Allergies in Childhood, módulo sobre asma, para pesquisa de prevalência de asma, estabelecendo seu escore e a nota de corte para discriminação de adultos asmáticos. MÉTODOS: Entrevistamos pacientes ambulatoriais adultos, 40 asmáticos e 38 controles, pareados por sexo e idade, utilizando o módulo de asma do International Study of Asthma and Allergies in Childhood, composto por oito aspectos dicotômicos de asma. Determinamos o escore e a nota de corte para discriminação de asmáticos, definindo sua sensibilidade, especificidade e índice de Youden. Validamos o método em contraposição ao diagnóstico clínico e funcional. A reprodutibilidade das questões individuais foi testada por meio de reentrevistas de metade dos pacientes após algumas semanas. RESULTADOS: O escore variou de 0 a 14 pontos. Um escore = 5 pontos permitiu discriminar pacientes asmáticos (sensibilidade = 93%, especificidade = 100% e índice de Youden = 0,93. A maioria das questões apresentou boa reprodutibilidade, observada em reentrevista após 48,2 ± 11,1 dias (Kappa e Kappa ponderado variando de 0,43 a 1,00 para as questões individuais. CONCLUSÃO: A validação de uma nota de corte permite uma interpretação alternativa às informações fornecidas pelo módulo de asma do International Study of Asthma and Allergies in Childhood, levando em conta o conjunto das informações e não somente as respostas individuais de cada questão em estudos de prevalência de asma em adultos.OBJECTIVE: To validate, for use in asthma prevalence studies, the asthma module of the standardized written questionnaire developed for use in the International Study of Asthma and Allergies in Childhood, establishing the score and cut-off point that would identify asthmatic adults. METHODS: We interviewed 78 adult outpatients (40 adult asthmatics and 38 age-matched and gender-matched controls

    6. Epidemiology and Management of Otitis Media in Children.

      Science.gov (United States)

      Giebink, G. Scott; Daly, Kathy

      1990-01-01

      This article focuses on definitions of middle ear inflammation (otitis media), the epidemiology of this disorder, brief considerations of pathophysiology and management, and possible future therapies. (DB))

    7. A biologic approach to environmental assessment and epidemiology

      National Research Council Canada - National Science Library

      Smith, Thomas J; Kriebel, David

      2010-01-01

      .... The two key fields of study on this issue, environmental epidemiology and exposure assessment, are still given separate names because of their separate historical roots and scientific traditions...

    8. Center for Surveillance, Epidemiology and Laboratory Services (CSELS)

      Data.gov (United States)

      Federal Laboratory Consortium — The mission of the Center for Surveillance, Epidemiology and Laboratory Services (CSELS) is to provide scientific service, expertise, skills, and tools in support of...

    9. Veracidad de un analizador de gasometría para determinar glucemia, respecto a un método de laboratorio convencional

      Directory of Open Access Journals (Sweden)

      Ítalo Moisés Saldaña O

      2014-07-01

      Full Text Available Objetivos: Determinar el grado de veracidad en los resultados de glucosa, medidos en un equipo de gasometría, mediante la comparación con un procedimiento de uso habitual en el laboratorio, siguiendo el procedimiento indicado en la guía EP9-A2 del Clinical and Laboratory Standards Institute (CLSI. Diseño: Estudio descriptivo con muestreo no probabilístico. Institución: Hospital Edgardo Rebagliati Martins, EsSalud, Lima, Perú. Material: Muestra sanguínea de 234 sujetos provenientes de los servicios de emergencia y la unidad de cuidados intensivos. Métodos: Se procesó glucemia en los equipos ADVIA1800 y el gasómetro ABL800.Se comparó los resultados de ambos analizadores siguiendo las directrices de la mencionada guía, además del análisis gráfico de Bland-Altman y el cálculo del coeficiente de concordancia correlación (CCC de Lin. Principales medidas de resultados: Concentración de glucosa sérica. Resultados: La media de glucemia obtenida fue 1,6 mg/dL mayor para ABL800 que para el ADVIA1800. Los dos métodos de medida seguían una relación lineal, obteniéndose un coeficiente de correlación de 0,9995, con un intervalo de confianza (IC al 95% de 0,9994 a 0,9996. Los resultados de glucosa del método de estudio fueron aceptables según los requerimientos de calidad, lo cual se confirmó con los análisis estadísticos de Bland-Altman y el valor del CCCL de 0,9995, con un IC de 95% de 0,9993 a 0,9996. Conclusiones: El analizador ABL800 resultó adecuado para la monitorización de glucemia; presentó una buena asociación lineal y veraz, cuando fue comparado con el método de referencia del laboratorio.

    10. Does terrestrial epidemiology apply to marine systems?

      Science.gov (United States)

      McCallum, Hamish I.; Kuris, Armand M.; Harvell, C. Drew; Lafferty, Kevin D.; Smith, Garriet W.; Porter, James

      2004-01-01

      Most of epidemiological theory has been developed for terrestrial systems, but the significance of disease in the ocean is now being recognized. However, the extent to which terrestrial epidemiology can be directly transferred to marine systems is uncertain. Many broad types of disease-causing organism occur both on land and in the sea, and it is clear that some emergent disease problems in marine environments are caused by pathogens moving from terrestrial to marine systems. However, marine systems are qualitatively different from terrestrial environments, and these differences affect the application of modelling and management approaches that have been developed for terrestrial systems. Phyla and body plans are more diverse in marine environments and marine organisms have different life histories and probably different disease transmission modes than many of their terrestrial counterparts. Marine populations are typically more open than terrestrial ones, with the potential for long-distance dispersal of larvae. Potentially, this might enable unusually rapid propagation of epidemics in marine systems, and there are several examples of this. Taken together, these differences will require the development of new approaches to modelling and control of infectious disease in the ocean.

    11. Role of data warehousing in healthcare epidemiology.

      Science.gov (United States)

      Wyllie, D; Davies, J

      2015-04-01

      Electronic storage of healthcare data, including individual-level risk factors for both infectious and other diseases, is increasing. These data can be integrated at hospital, regional and national levels. Data sources that contain risk factor and outcome information for a wide range of conditions offer the potential for efficient epidemiological analysis of multiple diseases. Opportunities may also arise for monitoring healthcare processes. Integrating diverse data sources presents epidemiological, practical, and ethical challenges. For example, diagnostic criteria, outcome definitions, and ascertainment methods may differ across the data sources. Data volumes may be very large, requiring sophisticated computing technology. Given the large populations involved, perhaps the most challenging aspect is how informed consent can be obtained for the development of integrated databases, particularly when it is not easy to demonstrate their potential. In this article, we discuss some of the ups and downs of recent projects as well as the potential of data warehousing for antimicrobial resistance monitoring. Copyright © 2015. Published by Elsevier Ltd.

    12. EPIDEMIOLOGY OF HUMAN RODENTICIDES POISONING IN BRAZIL

      Directory of Open Access Journals (Sweden)

      Maíra Costa Ferreira

      2013-09-01

      Full Text Available This work aims to analyze the epidemiological profile of human poisoning by rodenticides in Brazil and Regions, in the period 2000 to 2008. This is a descriptive epidemiological study based on secondary data from the National System of Toxic- harmacological Information. Calculations were performed in the incidence rate and fatality rate. The North and Northeast regions had the highest mortality rates for the period. Children from 1 to 4 years had high incidence in all regions except in Northeast, where teenagers were most affected. The rodenticide poisoning was more incident in urban areas and among females, and had attempt suicide as predominant circumstance. Although most cases have evolved for healing, there was almost 40% unconfirmed healing in the South region and 57% of ignored evolution in Southeast. Deaths caused by ingestion of rodenticides were below 5%. The rodenticide poisoning has remained in Brazil with a major public health problem and, despite the differences in the country, the poisoning profile did not change significantly between different regions.

    13. The epidemiology of bacterial meningitis in Kosovo.

      Science.gov (United States)

      Namani, Sadie A; Koci, Remzie A; Qehaja-Buçaj, Emine; Ajazaj-Berisha, Lindita; Mehmeti, Murat

      2014-07-14

      The purpose of this study was to present the epidemiologic features of bacterial meningitis in the developing country of Kosovo. Data were collected from active surveillance of bacterial meningitis cases treated at the University Clinical Center of Kosovo in the years 2000 (first post-war year) and 2010. Meningitis cases in 2000 compared with 2010 showed a 35.5% decline in incidence (from 4.8 to 3.1 cases per 100,000 population) and a decrease in the case fatality rate from 10% to 5%. In children, there was a lower mortality rate (5% versus 2%) and a lower incidence of neurological complications (13% versus 16%) as compared to adults (32% versus 10% and 16% versus 35%, respectively). Neisseria meningitidis was the most common pathogen of bacterial meningitis in both study periods. Bacterial meningitis was most prevalent in the pediatric population, and showed an increase in the median age, from three years in 2000 to seven years in 2010. A steady number of bacterial meningitis cases in adults throughout last decade (around 20 cases per year) was recorded. During the last decade, gradual changes have been observed in the epidemiology of bacterial meningitis that are unrelated to the introduction of new vaccines, but are partly due to the improvement of living conditions.

    14. Acute kidney injury: definition, diagnosis and epidemiology.

      Science.gov (United States)

      Rossaint, Jan; Zarbock, Alexander

      2016-02-01

      Acute kidney injury (AKI) is a common complication in hospitalized patients and great efforts by leading experts have been made in order to establish common definitions of AKI. The clinical use of these consensus definitions has led to a substantially improved understanding of AKI. In addition, the consensus definitions allow to compare AKI incidence and outcomes between different patient populations. As a result, it has become evident that AKI in the Western population represents a clinical syndrome with an incidence close to that of myocardial infarction. The aim of this review is to revisit the current concepts and definitions of AKI, to highlight its diagnosis, and to emphasize its epidemiological characteristics. Here, we will focus on the available literature reporting the epidemiology of AKI in critically ill patients. Sepsis, major surgery, and nephrotoxic drugs are the main causes of AKI in these patients, and its occurrence is associated with an increased risk for sustained chronic kidney injury. We also discuss the concept of renal angina as a possible future concept for improved clinical risk stratification to detect AKI. In this regard, we emphasize the importance of the use of novel biomarkers in the diagnosis of AKI, as they hold the potential to improve early diagnosis and prevention in the clinical setting.

    15. The epidemiology of dizziness and vertigo.

      Science.gov (United States)

      Neuhauser, H K

      2016-01-01

      This chapter gives an overview of the epidemiology of dizziness, vertigo, and imbalance, and of specific vestibular disorders. In the last decade, population-based epidemiologic studies have complemented previous publications from specialized settings and provided evidence for the high burden of dizziness and vertigo in the community. Dizziness (including vertigo) affects about 15% to over 20% of adults yearly in large population-based studies. Vestibular vertigo accounts for about a quarter of dizziness complaints and has a 12-month prevalence of 5% and an annual incidence of 1.4%. Its prevalence rises with age and is about two to three times higher in women than in men. Imbalance has been increasingly studied as a highly prevalent complaint particularly affecting healthy aging. Studies have documented the high prevalence of benign paroxysmal positional vertigo (BPPV) and vestibular migraine (VM), as well as of comorbid anxiety at the population level. BPPV and VM are largely underdiagnosed, while Menière's disease, which is about 10 times less frequent than BPPV, appears to be overdiagnosed. Risk factor research is only at its beginning, but has provided some interesting observations, such as the consistent association of vertigo and migraine, which has greatly contributed to the recognition of VM as a distinct vestibular syndrome. © 2016 Elsevier B.V. All rights reserved.

    16. Reproducing Epidemiologic Research and Ensuring Transparency.

      Science.gov (United States)

      Coughlin, Steven S

      2017-08-15

      Measures for ensuring that epidemiologic studies are reproducible include making data sets and software available to other researchers so they can verify published findings, conduct alternative analyses of the data, and check for statistical errors or programming errors. Recent developments related to the reproducibility and transparency of epidemiologic studies include the creation of a global platform for sharing data from clinical trials and the anticipated future extension of the global platform to non-clinical trial data. Government agencies and departments such as the US Department of Veterans Affairs Cooperative Studies Program have also enhanced their data repositories and data sharing resources. The Institute of Medicine and the International Committee of Medical Journal Editors released guidance on sharing clinical trial data. The US National Institutes of Health has updated their data-sharing policies. In this issue of the Journal, Shepherd et al. (Am J Epidemiol. 2017;186:387-392) outline a pragmatic approach for reproducible research with sensitive data for studies for which data cannot be shared because of legal or ethical restrictions. Their proposed quasi-reproducible approach facilitates the dissemination of statistical methods and codes to independent researchers. Both reproducibility and quasi-reproducibility can increase transparency for critical evaluation, further dissemination of study methods, and expedite the exchange of ideas among researchers. © The Author(s) 2017. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

    17. Satellite remote sensing in epidemiological studies.

      Science.gov (United States)

      Sorek-Hamer, Meytar; Just, Allan C; Kloog, Itai

      2016-04-01

      Particulate matter air pollution is a ubiquitous exposure linked with multiple adverse health outcomes for children and across the life course. The recent development of satellite-based remote-sensing models for air pollution enables the quantification of these risks and addresses many limitations of previous air pollution research strategies. We review the recent literature on the applications of satellite remote sensing in air quality research, with a focus on their use in epidemiological studies. Aerosol optical depth (AOD) is a focus of this review and a significant number of studies show that ground-level particulate matter can be estimated from columnar AOD. Satellite measurements have been found to be an important source of data for particulate matter model-based exposure estimates, and recently have been used in health studies to increase the spatial breadth and temporal resolution of these estimates. It is suggested that satellite-based models improve our understanding of the spatial characteristics of air quality. Although the adoption of satellite-based measures of air quality in health studies is in its infancy, it is rapidly growing. Nevertheless, further investigation is still needed in order to have a better understanding of the AOD contribution to these prediction models in order to use them with higher accuracy in epidemiological studies.

    18. Epidemiology of organising pneumonia in Iceland

      Science.gov (United States)

      Gudmundsson, G; Sveinsson, O; Isaksson, H J; Jonsson, S; Frodadottir, H; Aspelund, T

      2006-01-01

      Background Cryptogenic organising pneumonia (COP) has also been called idiopathic bronchiolitis obliterans organising pneumonia. In secondary organising pneumonia (SOP) the causes can be identified or it occurs in a characteristic clinical context. The aim of this study was to determine the incidence and epidemiological features of COP and SOP nationwide in Iceland over an extended period. Methods A retrospective study of organising pneumonia (OP) in Iceland over 20 years was conducted and the epidemiology and survival were studied. All pathological reports of patients diagnosed with or suspected of having COP or SOP in the period 1984–2003 were identified and the pathology samples were re‐evaluated using strict diagnostic criteria. Results After re‐evaluation, 104 patients fulfilled the diagnostic criteria for OP (58 COP and 46 SOP). The mean annual incidence of OP was 1.97/100 000 population (1.10/100 000 for COP and 0.87/100 000 for SOP). The mean age at diagnosis was 67 years with a wide age range. The most common causes of death were lung diseases other than OP, and only one patient died from OP. Patients with OP had a lower rate of survival than the general population, but there was no statistical difference between COP and SOP. Conclusions The incidence of OP is higher than previously reported, suggesting that OP needs to be considered as a diagnosis more often than has been done in the past. PMID:16809413

    19. Epidemiology of Isolated Acromioclavicular Joint Dislocation

      Directory of Open Access Journals (Sweden)

      Claudio Chillemi

      2013-01-01

      Full Text Available Background. Acromioclavicular (AC joint dislocation is a common shoulder problem. However, information about the basic epidemiological features of this condition is scarce. The aim of this study is to analyze the epidemiology of isolated AC dislocation in an urban population. Materials and Methods. A retrospective database search was performed to identify all patients with an AC dislocation over a 5-year period. Gender, age, affected side and traumatic mechanism were taken into account. X-rays were reviewed by two of the authors and dislocations were classified according to the Rockwood’s criteria. Results. A total of 108 patients, with a mean age of 37.5 years were diagnosed with AC dislocation. 105 (97.2% had an isolated AC dislocation, and 3 (2.8% were associated with a clavicle fracture. The estimated incidence was 1.8 per 10000 inhabitants per year and the male-female ratio was 8.5 : 1. 50.5% of all dislocations occurred in individuals between the ages of 20 and 39 years. The most common traumatic mechanism was sport injury and the most common type of dislocation was Rockwood type III. Conclusions. Age between 20 and 39 years and male sex represent significant demographic risk factors for AC dislocation.

    20. Epidemiology of Multiresistant Acinetobacter Infections in Bulgaria

      International Nuclear Information System (INIS)

      Savov, E.; Borisova, M.; Michailova, G.

      2007-01-01

      Evolution of bacteria towards resistance to antimicrobial drugs, including these with multidrug resistance, is very important issue for hospital epidemiology in all over the world. There are many papers about an increasing number of Acinetobacter baumannii blood stream and other type of infections in patients at military medical facilities in the Iraq / Kuwait region and in Afghanistan during Operation Enduring Freedom /OEF /. It has now become also a one of the major cause of hospital acquired infections in Bulgaria which due to its remarkable propensity to rapidly acquire resistance determinants to a wide range of antimicrobial drugs. According to the data obtained in Bulgaria, it can be concluded that the majority of the A.baumannii isolates was strikingly resistant, including the 3rd generation of cephalosporins, quinolones and also carbapenems, in the last years. Different methods / phenotypical and molecular methods, including PCR/ for a multidrug A.baumannii investigation and its clonality determination are needed, especially when the strains are not epidemiological related.(author)

    1. Clinical epidemiology of human AE in Europe.

      Science.gov (United States)

      Vuitton, D A; Demonmerot, F; Knapp, J; Richou, C; Grenouillet, F; Chauchet, A; Vuitton, L; Bresson-Hadni, S; Millon, L

      2015-10-30

      This review gives a critical update of the situation regarding alveolar echinococcosis (AE) in Europe in humans, based on existing publications and on findings of national and European surveillance systems. All sources point to an increase in human cases of AE in the "historic endemic areas" of Europe, namely Germany, Switzerland, Austria and France and to the emergence of human cases in countries where the disease had never been recognised until the end of the 20th century, especially in central-eastern and Baltic countries. Both increase and emergence could be only due to methodological biases; this point is discussed in the review. One explanation may be given by changes in the animal reservoir of the parasite, Echinococcus multilocularis (increase in the global population of foxes in Europe and its urbanisation, as well as a possible increased involvement of pet animals as definitive infectious hosts). The review also focuses onto 2 more original approaches: (1) how changes in therapeutic attitudes toward malignant and chronic inflammatory diseases may affect the epidemiology of AE in the future in Europe, since a recent survey of such cases in France showed the emergence of AE in patients with immune suppression since the beginning of the 21st century; (2) how setting a network of referral centres in Europe based on common studies on the care management of patients might contribute to a better knowledge of AE epidemiology in the future. Copyright © 2015. Published by Elsevier B.V.

    2. [Epidemiology of fatigue in general practice].

      Science.gov (United States)

      Fuhrer, R

      1994-11-01

      The epidemiology of fatigue is not well known in France, and this study reports on factors associated with fatigue in a sample of 3,784 general practice patients. Prevalence rates according to several definitions of fatigue are presented and factors are examined that have been reported to be associated with fatigue. Although 41.2% of the sample report having experienced symptoms of fatigue for at least three days, only 7.6% declare fatigue as a reason for consulting a doctor. Women report more symptoms of fatigue, but they do not consult more often than men for this reason. Age is strongly correlated with fatigue, but this is found only for men. Socioprofessional category bears no relationship to fatigue as a reason for consultation, however, the diagnosis of fatigue is more often attributed to professionals and upper management than it is to office staff or skilled and unskilled workers. We do find a strong relationship between depressive symptomatology as measured by the Center for Epidemiologic Studies (CES-D) and fatigue; nonetheless, fatigue is neither sensitive nor specific to the diagnosis of depression.

    3. Epidemiology of testicular cancer: an overview.

      Science.gov (United States)

      Garner, Michael J; Turner, Michelle C; Ghadirian, Parviz; Krewski, Daniel

      2005-09-01

      Testicular cancer is a rare disease, accounting for 1.1% of all malignant neoplasms in Canadian males. Despite the low overall incidence of testicular cancer, it is the most common malignancy among young men. The incidence rate of testicular cancer has been increasing since the middle of the 20th century in many western countries. However, the etiology of testicular cancer is not well understood. A search of the peer-reviewed literature was conducted to identify important articles for review and inclusion in this overview of the epidemiology of testicular cancer. Most of the established risk factors are related to early life events, including cryptorchidism, carcinoma in situ and in utero exposure to estrogens. Occupational, lifestyle, socioeconomic and other risk factors have demonstrated mixed associations with testicular cancer. Although there are few established risk factors for testicular cancer, some appear to be related to hormonal balance at various life stages. Lifestyle and occupational exposures occurring later in life may play a role in promoting the disease, although they are not likely involved in cancer initiation. In addition to summarizing the current epidemiologic evidence on risk factors for testicular cancer, we suggest future research directions that may elucidate the etiology of testicular cancer.

    4. Psoriasis: epidemiology, natural history, and differential diagnosis

      Directory of Open Access Journals (Sweden)

      Basko-Plluska JL

      2012-09-01

      Full Text Available Juliana L Basko-Plluska, Vesna Petronic-RosicDepartment of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USAAbstract: Psoriasis is a chronic, immune-mediated, inflammatory disease which affects primarily the skin and joints. It occurs worldwide, but its prevalence varies considerably between different regions of the world. Genetic susceptibility as well as environmental factors play an important role in determining the development and prognosis of psoriasis. Genome-wide association studies have identified many genetic loci as potential psoriasis susceptibility regions, including PSORS1 through PSORS7. Histocompatibility antigen (HLA studies have also identified several HLA antigens, with HLA-Cw6 being the most frequently associated antigen. Epidemiological studies identified several modifiable risk factors that may predispose individuals to developing psoriasis or exacerbate pre-existing disease. These include smoking, obesity, alcohol consumption, diet, infections, medications and stressful life events. The exact mechanism by which they trigger psoriasis remains to be elucidated; however, existing data suggest that they are linked through Th1-mediated immunological pathways. The natural history of psoriasis varies depending on the clinical subtype as well as special circumstances, including pregnancy and HIV infection. In general, psoriasis is a chronic disease with intermittent remissions and exacerbations. The differential diagnosis is vast and includes many other immune-mediated, inflammatory disorders.Keywords: psoriasis, epidemiology, natural history, differential diagnosis

    5. Para-equilibrium phase diagrams

      International Nuclear Information System (INIS)

      Pelton, Arthur D.; Koukkari, Pertti; Pajarre, Risto; Eriksson, Gunnar

      2014-01-01

      Highlights: • A rapidly cooled system may attain a state of para-equilibrium. • In this state rapidly diffusing elements reach equilibrium but others are immobile. • Application of the Phase Rule to para-equilibrium phase diagrams is discussed. • A general algorithm to calculate para-equilibrium phase diagrams is described. - Abstract: If an initially homogeneous system at high temperature is rapidly cooled, a temporary para-equilibrium state may result in which rapidly diffusing elements have reached equilibrium but more slowly diffusing elements have remained essentially immobile. The best known example occurs when homogeneous austenite is quenched. A para-equilibrium phase assemblage may be calculated thermodynamically by Gibbs free energy minimization under the constraint that the ratios of the slowly diffusing elements are the same in all phases. Several examples of calculated para-equilibrium phase diagram sections are presented and the application of the Phase Rule is discussed. Although the rules governing the geometry of these diagrams may appear at first to be somewhat different from those for full equilibrium phase diagrams, it is shown that in fact they obey exactly the same rules with the following provision. Since the molar ratios of non-diffusing elements are the same in all phases at para-equilibrium, these ratios act, as far as the geometry of the diagram is concerned, like “potential” variables (such as T, pressure or chemical potentials) rather than like “normal” composition variables which need not be the same in all phases. A general algorithm to calculate para-equilibrium phase diagrams is presented. In the limit, if a para-equilibrium calculation is performed under the constraint that no elements diffuse, then the resultant phase diagram shows the single phase with the minimum Gibbs free energy at any point on the diagram; such calculations are of interest in physical vapor deposition when deposition is so rapid that phase

    6. Marcadores para la Realidad Aumentada para fines educativos

      Directory of Open Access Journals (Sweden)

      María Reina Zarate Nava

      2013-12-01

      Full Text Available La Realidad Aumentada (AR es considerada por algunos expertos como la tecnología en crecimiento para el 2014, en diferentes sectores: ingeniería, educación, juegos y negocios, siendo este último el más usado en él 2013. Sin embargo en el sector educativo la AR se presenta en algunos proyectos que se han desarrollado para diferentes áreas de las ciencias, como Química, Física y Matemáticas, lo anterior con el objetivo de facilitar el proceso de Enseñanza-Aprendizaje. En el presente artículo se presenta el modelo de patrones utilizado para un Proyecto AR enfocado en Química, el cual presenta un conjunto de patrones que fueron valorados para facilitar el rastreo de los objetos y a su vez el entendimiento de algunos materiales de los laboratorios de Química I.

    7. Algoritmos para problemas de empacotamento

      OpenAIRE

      Eduardo Candido Xavier

      2006-01-01

      Resumo: Neste trabalho estudamos diversos problemas de empacotamento considerados NP-difíceis. Assumindo a hipótese de que P ? NP, sabemos que não existem algoritmos eficientes (complexidade de tempo polinomial) exatos para resolver tais problemas. Uma das abordagens consideradas para tratar tais problemas é a de algoritmos de aproximação, que são algoritmos eficientes e que geram soluções com garantia de qualidade. Neste trabalho apresentamos alguns algoritmos aproximados para problemas de e...

    8. Mapping epidemiology's past to inform its future: metaknowledge analysis of epidemiologic topics in leading journals, 1974-2013.

      Science.gov (United States)

      Trinquart, Ludovic; Galea, Sandro

      2015-07-15

      An empiric perspective on what epidemiology has studied over time might inform discussions about future directions for the discipline. We aimed to identify the main areas of epidemiologic inquiry and determine how they evolved over time in 5 high-impact epidemiologic journals. We analyzed the titles and abstracts of 20,895 articles that were published between 1974 and 2013. In 5 time periods that reflected approximately equal numbers of articles, we identified the main topics by clustering terms based on co-occurrence. Infectious disease and cardiovascular disease epidemiology were the prevailing topics over the 5 periods. Cancer epidemiology was a major topic from 1974 to 2001 but disappeared thereafter. Nutritional epidemiology gained relative importance from 1974 to 2013. Environmental epidemiology appeared during 1996-2001 and continued to be important, whereas 2 clusters related to methodology and meta-analysis in genetics appeared during 2008-2013. Several areas of epidemiology, including injury or psychiatric epidemiology, did not make an appearance as major topics at any time. In an ancillary analysis of 6 high-impact general medicine journals, we found patterns of epidemiologic articles that were overall consistent with the findings in epidemiologic journals. This metaknowledge investigation allowed identification of the dominant topics in and conversely those that were absent from 5 major epidemiologic journals. We discuss implications for the field. © The Author 2015. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

    9. El abordaje epidemiológico de las desigualdades en salud a nivel local The epidemiological approach to health inequalities at the local level

      Directory of Open Access Journals (Sweden)

      Marcio Alazraqui

      2007-02-01

      Full Text Available Para responder la pregunta ¿cuáles son los usos y limitaciones de la epidemiología en la reducción de las desigualdades en el nivel local? se problematiza el "papel" de la epidemiología. La hipótesis es que la epidemiología produce conocimiento útil a la gestión en el nivel local para el desarrollo de intervenciones dirigidas a la reducción de desigualdades en salud. Estas desigualdades se expresan en un espacio construido por colectivos humanos en procesos sociales e históricos. La producción de conocimiento epidemiológico en el nivel local debe estar orientada a dar soporte a las acciones de un actor social en situación y en un determinado escenario. Por eso se revalorizan los estudios ecológicos y la georreferencia. Esta producción y aplicación de conocimiento es también un fenómeno organizacional. Se entienden las organizaciones como "redes de conversaciones". Se concluye que las acciones estratégicas y las acciones comunicativas de los trabajadores de salud deben constituirse como eje central en la definición de nuevos modelos de cuidado y de gestión comprometidos con la reducción de desigualdades en salud, donde la epidemiología cumple un rol relevante.What are the advantages and limitations of epidemiology for decreasing health inequalities at the local level? To answer this question, the current article discusses the role of epidemiology. The hypothesis is that epidemiology produces useful knowledge for local management of interventions aimed at reducing health inequalities, expressed in spaces built by human communities through social and historical processes. Local production of epidemiological knowledge should support action by social actors in specific situations and contexts, thus renewing the appreciation for ecological designs and georeference studies. Such knowledge output and application are also an organizational phenomenon. Organizations can be seen as "conversational networks". In conclusion, strategic

    10. Hacia directrices y conceptos de diseño de vialidad sustentable: el caso del corredor fluvial del río Mapocho ─sección occidental─ y su entorno. / Guidelines and concepts to design sustainable transportation: the western section of the corridor of the Mapocho River and its environment.

      Directory of Open Access Journals (Sweden)

      María Patricia Henríquez Orellana

      2010-12-01

      Full Text Available Se explora un polígono donde existe un potencial de desarrollo sostenible conteniendo el tramo poniente del río Mapocho, posible de constituirse en un corredor fluvial recreacional y de transporte como uno de los elementos estructuradores metropolitanos. Se trata del uso del espacio corredor del río Mapocho y su entorno inmediato para la integración urbana-regional. La investigación FONDECYT 1090199 – 2009/2010 planteó que resolver la conformación de éste corredor requiere un fortalecimiento integral de la vialidad que mejore la accesibilidad, conectividad y conexidad del corredor, potenciando un sistema vial asociado al río, pero no perturbador del río; diversificado y articulador de actividades pertinentes junto y eventualmente sobre el territorio de la movilidad fluvial; que conecte los asentamientos de borde, contribuya a la producción de espacio público para la recreación y esparcimiento tranquilo de los habitantes, y conjuntamente en las áreas rurales facilite la coexistencia con la actividad agraria y campesina. Esto permitiría la integración plena del río a la vida metropolitana y periurbana de Santiago. Dicha acción requiere ser abordada desde un ordenamiento territorial ambientalmente sustentable y no sólo desde la ingeniería./The western section of the Mapocho river is an especial area for a future sustainable development. The author essay the possibility of this section as a recreational and transportation corridor that could be also a integration node for de city and the region.

    11. Tesauros en HTML. Un modelo de diseño y estructura para su consulta en la malla mundial (WWW.

      Directory of Open Access Journals (Sweden)

      Valle Bracero, Antonio

      2000-06-01

      Full Text Available A new model is described for outliníng and structuring thesauri for their use as an aid in the database indexing through the World Wide Web (WWW. Several models used in the different on-line help managers were studied and used as main sources on the start up: AcroRead, HTML Help, NetHelp, etc. These on line help systems are used to provide easy access for the users to the operatíon guidelines for several commercial software packages. For this work the guidelines included in the «Microsoft's HTML Help» were used.

      The format used for the prototype thesauri in the trials is the native format of the CAT (Confección Automática de Tesauros application developed in CINDOC. From this format and using the methodology outlined in this paper, an HTML file system including search indexes, location indexes and links was developed. This file system allows the user to go to the precise point of the text that refers to the search term. In that point the user will find a number of indications about the relationship between the search term and cither related items. These later ones can be also used as starting points for new searches.

      The preliminary trials made with different thesauri, both on-line and on CD-ROM have provided very good results.

      Se describe un modelo de diseño y estructura de tesauros para su consulta y utilización en tratamientos de indización de bases de datos a través de la malla mundial (WWW. Como fuentes de estudio de partida se analizaron los modelos empleados en diferentes gestores de documentación de ayuda: AcroRead, HTML Help, NetHelp, etc., utilizados para facilitar, a los usuarios de las diferentes aplicaciones, las normas de uso de las mismas. Para la elaboración del trabajo, se han adoptado las directrices expuestas en «Microsoft's HTML Help».

      El formato origen de los tesauros piloto, empleados en las pruebas, ha sido el establecido para la aplicación CAT (Confección Automática de Tesauros

    12. EPIDEMIOLOGY OF PEDIATRIC SPORTS INJURIES: INDIVIDUAL SPORTS

      Directory of Open Access Journals (Sweden)

      Dennis J. Caine

      2005-06-01

      Full Text Available The objective of the book is to review comprehensively what is known about the distribution and determinants of injury rates in a variety of individual sports, and to suggest injury prevention measures and guidelines for further research. This book provides comprehensive compilation and critical analysis of epidemiological data over children's individual sports: including equestrian, gymnastics, martial arts, skiing and snowboarding, tennis, track and field, and wrestling. This book encourages coaches and sports administrators to discuss rules, equipment standards, techniques, and athlete conditioning programs. In turn, they can inform parents about the risks and how they can help their children avoid or limit injury in sports. A common, uniform strategy and evidence-based approach to organizing and interpreting the literature is used in all chapters. All the sports-specific chapters are laid out with the same basic headings, so that it is easy for the reader to find common information across chapters. Chapter headings are: 1 Epidemiology of children's individual sports injuries, 2 Equestrian injuries, 2 Gymnastics injuries, 3 Martial arts injuries, 4 Skiing and snowboard injuries, 5 Tennis injuries, 6 Track and field injuries, 7 Wrestling injuries, 8 Injury prevention and future research. Chapter headings include: i Incidence of injury, ii Injury characteristics, iii Injury severity, iv njury risk factors, v Suggestions for injury prevention, vi Suggestions for further research. In each sports-specific chapter, an epidemiological picture has been systematically developed from the data available in prospective cohort, retrospective cohort, case-control, and cross-sectional studies. The tables are numerous, helpful and very useful. The book provides a very useful resource for sport scientist, pediatricians, family practitioners and healthcare professionals in the field of child and adolescent injury and prevention The readers are going to

    13. Radiation epidemiology: a perspective on Fukushima

      International Nuclear Information System (INIS)

      Boice, John D Jr

      2012-01-01

      For nearly 100 years, epidemiologic studies of human populations exposed to ionising radiation have provided quantitative information on health risks. High dose deterministic (tissue reaction) effects result when sufficient numbers of functioning cells are killed, such as in bone marrow depression that can lead to death. Lower dose stochastic effects are probabilistic in nature and include an increased risk of cancer later in life and heritable genetic defects, although genetic conditions in the children of irradiated parents have yet to be convincingly demonstrated. Radiation studies are of diverse populations and include not only the Japanese atomic bomb survivors, but also patients treated with radiation for malignant and non-malignant disease; patients exposed for diagnostic purposes; persons with intakes of radionuclides; workers occupationally exposed; and communities exposed to environmental and accidentally released sources of radiation. Much is known about radiation and its risks. The major unanswered question in radiation epidemiology, however, is not whether radiation causes cancer, but what the level of risk is following low dose (<100 mSv) or low dose rate exposures. Paracelsus is credited with first articulating that the 'poison is in the dose', which for radiation epidemiology translates as 'the lower the dose, the lower the risk' and, an important corollary, the lower the dose, the greater the difficulty in detecting any increase in the number of cancers possibly attributable to radiation. In contrast to the Chernobyl reactor accident, the Fukushima reactor accident has to date resulted in no deterministic effects and no worker deaths. Estimates to date of population doses suggest very low uptakes of radioactive iodine which was a major determinant of the epidemic of thyroid cancer following childhood exposures around Chernobyl. The estimates to date of population doses are also much lower (and the distribution much narrower) than the doses for

    14. Titanium dioxide: inhalation toxicology and epidemiology.

      Science.gov (United States)

      Hext, Paul M; Tomenson, John A; Thompson, Peter

      2005-08-01

      Titanium dioxide (TiO(2)) is manufactured worldwide in large quantities for use in a wide range of applications and is normally considered to be toxicologically inert. Findings of tumours in the lungs of rats exposed chronically to high concentrations of TiO(2), but not in similarly exposed mice or hamsters, suggest that the tumorigenic response may be a rat-specific phenomenon but nonetheless raises concerns for potential human health effects. With the limited toxicological understanding of species differences in response to inhaled TiO(2) and a similarly limited amount of epidemiological information with respect to TiO(2) exposure in the workplace, a consortium of TiO(2) manufacturers in Europe (under the European Chemistry Industry Council; CEFIC) and in North America (under the American Chemistry Council; ACC) initiated a programme of research to investigate inter-species differences as a result of exposure to TiO(2) and to conduct detailed epidemiological surveys of the major manufacturing sites. The toxicology studies exposed rats, mice and hamsters to pigment-grade TiO(2) (PG-TiO(2), 0, 10, 50 and 250 mg m(-3)) or ultrafine TiO(2) (UF-TiO(2), 0, 0.5, 2 and 10 mg m(-3)) for 90 days and the lung burdens and tissue responses were evaluated at the end of the exposure period and for up to 1 year after exposure. Results demonstrated clear species differences. Rats and mice had similar lung burdens and clearance rates while hamsters showed high clearance rates. At high lung particle burdens, rats showed a marked progression of histopathological lesions throughout the post-exposure period while mice and hamsters showed minimal initial lesions with recovery apparent during the post-exposure period. Lung neutrophil responses, a sensitive marker of inflammatory changes, reflected the development or recovery of the histopathological lesions. The use of surface area rather than gravimetric lung burden provided closer correlates of the burden to the biological effect

    15. La otra transición epidemiológica: hitos en el desarrollo de la epidemiología de los factores de riesgo en Colombia

      Directory of Open Access Journals (Sweden)

      Álvaro Javier Idrovo

      2008-12-01

      Full Text Available Este artículo describe la manera como emergió la epidemiología de los factores de riesgo en Colombia y algunos desarrollos posteriores. Los orígenes de la epidemiología de los factores de riesgo se relacionan con la situación sanitaria nacional de mediados del siglo XX, que muestran un cambio en el perfil de presentación de enfermedades infecciosas y nutricionales hacia un perfil con predominio de enfermedades crónicas y traumatismos. Se describen los principales hitos en la historia de la epidemiología de los factores de riesgo nacional: los estudios sobre bocio endémico, cáncer gástrico y cáncer de cuello uterino, y efectos adversos de la desnutrición infantil, y las encuestas de salud locales. El influjo que la Fundación Rockefeller y la Organización Panamericana de la Salud tuvieron sobre la enseñanza de la epidemiología en Colombia es destacado. Finalmente, se describen las principales líneas de investigación actuales y se sugieren algunas pautas de investigación para los futuros historiadores de la salud pública y la epidemiología colombiana.

    16. Epidemiology of Patellar Tendinopathy in Elite Male Soccer Players

      NARCIS (Netherlands)

      Hägglund, Martin; Zwerver, Johannes; Ekstrand, Jan

      Background: Patellar tendinopathy is common among athletes in jumping sports and in sports with prolonged repetitive stress of the knee extensor apparatus. The epidemiology in soccer is not well described. Purpose: This study was undertaken to investigate and describe the epidemiology of patellar

    17. The Rwanda Field Epidemiology and Laboratory Training Program ...

      African Journals Online (AJOL)

      The Rwanda Field Epidemiology and Laboratory Training Program (RFELTP) is a 2-year public health leadership development training program that provides applied epidemiology and public health laboratory training while the trainees provide public health service to the Ministry of Health. RFELTP is hosted at the National ...

    18. Bacterial meningitis: epidemiology, herd protection, clinical characteristics, and risk assessment

      NARCIS (Netherlands)

      Bijlsma, M.W.

      2016-01-01

      This thesis studied the epidemiology of community-acquired bacterial meningitis after the nationwide implementation of paediatric conjugate vaccines, as well as the long-term epidemiology of invasive meningococcal disease and neonatal group B streptococcal disease in the Netherlands. Furthermore,

    19. Meta-analysis in epidemiology | Yach | South African Medical Journal

      African Journals Online (AJOL)

      Meta-analysis is the structured and systematic qualitative and quantitative integration of the results of several independent studies (Le. the epidemiology of results). As in any epidemiological study, a meta-analysis needs to start with clearly stated aims and objectives. Attention needs to be paid to selection bias in selecting ...

    20. Epidemiology of injuries in female high school soccer players ...

      African Journals Online (AJOL)

      Background: Sport is a compulsory activity in schools in South Africa. Female learners participating in soccer are more vulnerable to injuries than males. Objective: This study determined the epidemiology of injuries in female high school soccer players. Methods: A cross sectional survey captured the epidemiology of ...

    1. The epidemiology and control of onchocerciasis in West-Africa

      NARCIS (Netherlands)

      J.H.F. Remme

      1989-01-01

      textabstractThe present thesis deals with research which has been undertaken since 1983 with the aim of finding answers to the three main epidemiological questions which have been discussed above, i.e. I.-What are the epidemiological patterns of ocular onchocerciasis in West Africa and what is

    2. The role of laboratory confirmations and molecular epidemiology in ...

      African Journals Online (AJOL)

      This review reports on the role of laboratory confirmation and molecular epidemiology in global eradication of measles. The role of laboratory confirmation and molecular epidemiology in defining the origins of measles outbreaks cannot be overemphasized. New serological tests based on recombinant proteins detect only a ...

    3. Molecular Epidemiology of Bovine Tuberculosis and most Common ...

      African Journals Online (AJOL)

      Even though tuberculosis is endemic in Nigeria, information on the epidemiology of the disease especially bovine tuberculosis is still very scanty. Variable Number of Tandem Repeat (VNTR) was carried out on 113 tissue samples to have an idea of not only the epidemiology of bovine tuberculosis but also the most common ...

    4. Epidemiology and effects on health of low ionizing radiation doses

      International Nuclear Information System (INIS)

      Rodriguez Artalejo, F.; Andres Manzano, B. de; Rel Calero, J. del

      1997-01-01

      This article describes the concept and aims of epidemiology, its methods and contribution to the knowledge of the effects of low ionizing radiation doses on health. The advantages of epidemiological studies for knowing the consequences of living near nuclear facilities and the effects of occupational exposure to radiations are also described. (Author) 43 refs

    5. Validity of various epidemiological approaches to assessing radon health risk

      International Nuclear Information System (INIS)

      Conrath, S.M.

      1990-01-01

      In this paper various epidemiologic study designs are defined and evaluated for their utility in assessing radon health risk. The strengths and limitations of these approaches are addressed. Common pitfalls and errors of epidemiologic method are delineated with examples of causes and remedies

    6. Epidemiological reference ranges for low-density lipoprotein ...

      African Journals Online (AJOL)

      Although there is widespread acceptance that total cholesterol (TC) value reference ranges should be based on epidemiological rather than statistical considerations, the epidemiological action limits for Iow-density lipoprotein cholesterol (LDL-C) are still incomplete and only statistical reference ranges for apolipoprotein B ...

    7. Epidemiology, public health, and the rhetoric of false positives

      DEFF Research Database (Denmark)

      Blair, Aaron; Saracci, Rodolfo; Vineis, Paolo

      2009-01-01

      BACKGROUND: As an observational science, epidemiology is regarded by some researchers as inherently flawed and open to false results. In a recent paper, Boffetta et al. [Boffetta P, McLaughlin JK, LaVecchia C, Tarone RE, Lipworth L, Blot WJ. False-positive results in cancer epidemiology: a plea f...

    8. The importance of recent results from epidemiology

      International Nuclear Information System (INIS)

      Harley, N.H.; Robbins, E.S.

      1992-01-01

      The underground miner radon epidemiology reported in the past 15 years has led to modeling of the lung cancer risk from 222 Rn exposure, quantitating the risk in present day mines, extrapolating the risk to environmental 222 Rn exposure, and relating effects of low and high LET radiation. Many countries have occupational guidelines that now better conform to the actual risks experienced in mining and some have governmental guidelines regarding environmental exposure which, when fully implemented, can impose substantial benefit but also substantial cost to society. For this reason it important to follow the health of underground mining populations to better understand the risk that has been deduced, inferred or calculated. The purpose of this report is to describe the most recent results and advances. In this examination a biological basis for a new model for 222 Rn decay product risk is developed

    9. Recommendations for epidemiological studies on COPD

      DEFF Research Database (Denmark)

      Bakke, P S; Rönmark, E; Eagan, T

      2011-01-01

      of the disease and definitions of the risk factors. Few community studies have examined phenotypes of COPD and included other ways of characterising the disease beyond that of spirometry. The objective of the present Task Force report is to present recommendations for the performance of general population...... for planning and performing an epidemiological study on COPD. The main message of the paper is that thorough planning is worth half the study. It is crucial to stick to standardised methods and good quality control during sampling. We recommend collecting biological markers, depending on the specific......The prevalence of chronic obstructive pulmonary disease (COPD) has been extensively studied, especially in Western Europe and North America. Few of these data are directly comparable because of differences between the surveys regarding composition of study populations, diagnostic criteria...

    10. Structured population models in biology and epidemiology

      CERN Document Server

      Ruan, Shigui

      2008-01-01

      This book consists of six chapters written by leading researchers in mathematical biology. These chapters present recent and important developments in the study of structured population models in biology and epidemiology. Topics include population models structured by age, size, and spatial position; size-structured models for metapopulations, macroparasitc diseases, and prion proliferation; models for transmission of microparasites between host populations living on non-coincident spatial domains; spatiotemporal patterns of disease spread; method of aggregation of variables in population dynamics; and biofilm models. It is suitable as a textbook for a mathematical biology course or a summer school at the advanced undergraduate and graduate level. It can also serve as a reference book for researchers looking for either interesting and specific problems to work on or useful techniques and discussions of some particular problems.

    11. The epidemiology of bicyclist's collision accidents

      DEFF Research Database (Denmark)

      Larsen, L. B.

      1994-01-01

      of bicyclists and risk situations. The findings should make a basis for preventive programmes in order to decrease the number and severity of bicyclists collision accidents. Data from the emergency room in a 2 year period was combined with data from questionnaires. The study group consisted of 1021 bicyclists......The number of bicyclists injured in the road traffic in collision accidents and treated at the emergency room at Odense University Hospital has increased 66% from 1980 to 1989. The aim of this study was to examine the epidemiology of bicyclist's collision accidents and identify risk groups...... injured in collision accidents, and 1502 bicyclists injured in single accidents was used as a reference group. The young bicyclists 10-19 years of age had the highest incidence of injuries caused by collision accidents. The collision accidents had different characteristics according to counterpart. One...

    12. Childhood Tuberculosis: Epidemiology, Diagnosis, Treatment, and Vaccination

      Directory of Open Access Journals (Sweden)

      Kuo-Sheng Tsai

      2013-10-01

      Full Text Available Despite the existence of a government-run tuberculosis (TB control program, the current nationwide burden of TB continues to be a public health problem in Taiwan. Intense current and previous efforts into diagnostic, therapeutic, and preventive interventions have focused on TB in adults, but childhood TB has been relatively neglected. Children are particularly vulnerable to severe disease and death following infection, and children with latent infections become reservoirs for future transmission following disease reactivation in adulthood, thus fueling future epidemics. Additional research, understanding, and prevention of childhood TB are urgently needed. This review assesses the epidemiology, diagnosis, treatment, and relevant principles of TB vaccine development and presents efficacy data for the currently licensed vaccines.

    13. Epidemiology of adverse drug reactions in Europe

      DEFF Research Database (Denmark)

      Bouvy, Jacoline C; De Bruin, Marie L; Koopmanschap, Marc A

      2015-01-01

      Adverse drug reactions (ADRs) cause considerable mortality and morbidity but no recent reviews are currently available for the European region. Therefore, we performed a review of all epidemiological studies quantifying ADRs in a European setting that were published between 1 January 2000 and 3...... September 2014. Included studies assessed the number of patients who were admitted to hospital due to an ADR, studies that assessed the number of patients who developed an ADR during hospitalization, and studies that measured ADRs in the outpatient setting. In total, 47 articles were included in the final...... review. The median percentage of hospital admissions due to an ADR was 3.5 %, based on 22 studies, and the median percentage of patients who experienced an ADR during hospitalization was 10.1 %, based on 13 studies. Only five studies were found that assessed ADRs occurring in the outpatient setting...

    14. Epidemiology of bladder cancer. A second look

      Energy Technology Data Exchange (ETDEWEB)

      Wynder, E.L.; Goldsmith, R.

      1977-09-01

      A case-control study among 574 male and 158 female bladder cancer patients and equal numbers of matched controls was conducted between 1969 and 1974 in 17 hospitals in six United States cities. We determined that cigarette smokers of both sexes were at higher relative risk than nonsmokers. Cigarette smoking was responsible for about one-half of male and one-third of female bladder cancer. There was an excess of bladder cancer patients with some previous occupational exposure, such as rubber, chemicals, and textiles. A weak association with coffee drinking, which appeared to be independent of smoking, was found for males. Users of artificial sweetners were not over-represented among the cases. The authors conclude that the epidemiologic pattern of bladder cancer cannot be fully accounted for by cigarette smoking and occupational exposure and suggest a series of metabolic studies to assess the role of additional factors, such as nutrition.

    15. AIDS: a new frontier in epidemiology.

      Science.gov (United States)

      Baker, S A

      1994-01-01

      HIV infection has become a pandemic. As such, it is the most recent inclusion to epidemiology studies. A review of past epidemics allows a different perspective on the current status of scientific knowledge regarding AIDS. HIV is a retrovirus, one of three groups identified. The other two groups are commonly referred to as HTLV I and II and do not cause AIDS. Two forms of HIV (HIV-1 and HIV-2) make up the third group, HTLV-III. As with any research, various theories are formed, tested, and often rejected. Some theories receive excessive publicity before testing, resulting in incorrect public beliefs that become myths. The cumulative number of cases of AIDS in the United States is 361,509, as of December 31, 1993. Healthcare workers experience multiple opportunities for exposure to the infection in the course of their duties. Based on data from the 1993 BMET/CE survey, several biohazard issues, as well as preventive measures, are discussed.

    16. [Epidemiology of nosocomial infections in neonates].

      Science.gov (United States)

      Lachassinne, E; Letamendia-Richard, E; Gaudelus, J

      2004-03-01

      Epidemiology of nosocomial infections in neonates has to be described according to our definitions (early onset GBS diseases excluded) and according to levels of care. Nosocomial risk exists in maternity departments (3% in postnatal beds), incidence rates are 7.5-12.7% or 1.3-8.5 per 1000 days in neonatal care units and 14.2% or 11.7 per 1000 days in neonatal intensive care units (NICU). Gram-positive cocci bloodstream infections are the most common nosocomial infections in NICU but viral gastroenteritis are more frequent in neonatal care units. Risk factors are low birthweight, small gestational age and intravascular catheter in NICU, and for viral nosocomial infections, visits and winter outbreaks.

    17. Clinical epidemiological aspects of chronic lymphoid leukaemia

      International Nuclear Information System (INIS)

      Rodriguez Brunet, Marisol; Hernandez Galano, Geldris P; Suarez Beyries, Lidia C; Duverger Magdaleon, Ernesto

      2011-01-01

      A descriptive and retrospective study of 71 patients with chronic lymphoid leukemia, attended at the Hematology Service from 'Dr Juan Bruno Zayas Alfonso' Teaching General Hospital in Santiago de Cuba was carried out from January, 2001 to November, 2006, in order to identify some clinical epidemiological variables on them, to show the therapeutical variables more used, as well as to assess survival, mortality, and the main causes of the clinical entity. Elderly, male sex, and high risk category related to advanced stage were predominant in the series. The therapeutical schedule of chlorambucil and prednisone was the most used, achieving good results in the majority of the case material. The survival of patients, in general, ranged among 1-5 years, whereas deaths occurred due to disease progression, infectious respiratory processes, pro-lymphocytic transformation, second neoplasias, and strokes. (author)

    18. Evaluation of endometrial cancer epidemiology in Romania.

      Science.gov (United States)

      Bohîlțea, R E; Furtunescu, F; Dosius, M; Cîrstoiu, M; Radoi, V; Baroș, A; Bohîlțea, L C

      2015-01-01

      Endometrial cancer represents the most frequent gynecological malignant affection in the developed countries, in which the incidence of cervical cancer has significantly decreased due to the rigorous application of screening methods and prophylaxis. According to its frequency, endometrial cancer is situated on the fourth place in the category of women's genital-mammary malignant diseases, after breast, cervical and ovarian cancer in Romania. The incidence and mortality rates due to endometrial cancer have registered an increasing trend worldwide and also in Romania, a significant decrease of the age of appearance for the entire endometrial pathology sphere being noticed. At the national level, the maximum incidence is situated between 60 and 64 years old, the mortality rate of the women under 65 years old being high in Romania. The study evaluates endometrial cancer, from an epidemiologic point of view, at the national level compared to the international statistic data.

    19. Epidemiological studies in high background radiation areas

      International Nuclear Information System (INIS)

      Akiba, Suminori

      2012-01-01

      Below the doses of 100-200 mSv of radiation exposure, no acute health effect is observed, and the late health effects such as cancer are yet unclear. The problems making the risk evaluation of low dose radiation exposure difficult are the fact that the magnitude of expected health effects are small even if the risk is assumed to increase in proportion to radiation doses. As a result, studies need to be large particular when dealing with rare disease such as cancer. In addition, the expected health effects are so small that they can easily be masked by lifestyles and environmental factors including smoking. This paper will discuss cancer risk possibly associated with low-dose and low-dose rate radiation exposure, describing epidemiological studies on the residents in the high-background radiation areas. (author)

    20. Epidemiology and antifungal resistance in invasive candidiasis

      Directory of Open Access Journals (Sweden)

      Rodloff AC

      2011-04-01

      Full Text Available Abstract The epidemiology of Candida infections has changed over the last two decades: The number of patients suffering from such infections has increased dramatically and the Candida species involved have become more numerous as Candida albicans is replaced as an infecting agent by various non-C. albicans species (NAC. At the same time, additional antifungal agents have become available. The different Candida species may vary in their susceptibility for these various antifungals. This draws more attention to in vitro susceptibility testing. Unfortunately, several different test methods exist that may deliver different results. Moreover, clinical breakpoints (CBP that classify test results into susceptible, intermediate and resistant are controver- sial between CLSI and EUCAST. Therefore, clinicians should be aware that interpretations may vary with the test system being followed by the microbiological laboratory. Thus, knowledge of actual MIC values and pharmacokinetic properties of individual antifungal agents is important in delivering appropriate therapy to patients