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Sample records for eno kussaku keikaku

  1. Drilling series. 4. ; Planning geothermal drilling (rotary type). Kussaku series. 4. ; Chinetsusei no kussaku keikaku (shutoshite rotary gata)

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    Ito, T. (S.K. Engineering Co. Ltd., Tokyo (Japan))

    1994-01-31

    The present report explained how to plan the drilling of geothermal well, and select the easing, drilling mud water and drilling rig in order to obtain the steam and hot water. The geothermal wells can be generally classified into exploration wells, production wells and reduction wells. The exploration well is a well to survey the underground strata, geological structure, and existence of steam and hot water, while the production well is a well to produce the steam and hot water. The reduction well is a well to condense the hot water produced by the production well and steam having passed through the power-generating turbine, and return them as condensate underground. The geothermal well is characterized by its high temperature, mud leakage, corrosive matter and scale, all of which make its drilling difficult and its management troublesome for the production and reduction. To plan the drilling, the order of processing are distinct conditioning of drilling differently by type of well, collection of geological survey data, programing for the casing and selection of drilling rig. The present report also gave the stress to affect the casing and standard of steel pipes to be used for the casing. 3 figs., 4 tabs.

  2. Problems in green improvement projects in recent city planning. Kinnen no toshi keikaku ni okeru ryokuchi keikaku eno kadai

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    Funabiki, T. (Ministry of Construction, Tokyo (Japan))

    1992-08-06

    The present city plans are questioned on the formation of a good city environment, improvement of mansion/building supply, due to the new city problems on the Tokyo concentration and re-increase of the land value recently. Based on the discussion of the central city planning council, various improvement of the system were made by government. As a structure plan of the city, the green area plan that the balance between the urban land use and the national land use is distributed, must be included. As the problem of the green area plan on the system of city plan, this paper explained the distinguish between city area and city adjustment area, the green master plan about the green area preservation in long time, the green area system corresponded to the policy for realizing the plan of preserving the green area mainly, and the park work and green area policy corresponded to the policy for realizing the plan of creating the green area.

  3. Low shear stress induces vascular eNOS uncoupling via autophagy-mediated eNOS phosphorylation.

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    Zhang, Jun-Xia; Qu, Xin-Liang; Chu, Peng; Xie, Du-Jiang; Zhu, Lin-Lin; Chao, Yue-Lin; Li, Li; Zhang, Jun-Jie; Chen, Shao-Liang

    2018-05-01

    Uncoupled endothelial nitric oxide synthase (eNOS) produces O 2 - instead of nitric oxide (NO). Earlier, we reported rapamycin, an autophagy inducer and inhibitor of cellular proliferation, attenuated low shear stress (SS) induced O 2 - production. Nevertheless, it is unclear whether autophagy plays a critical role in the regulation of eNOS uncoupling. Therefore, this study aimed to investigate the modulation of autophagy on eNOS uncoupling induced by low SS exposure. We found that low SS induced endothelial O 2 - burst, which was accompanied by reduced NO release. Furthermore, inhibition of eNOS by L-NAME conspicuously attenuated low SS-induced O 2 - releasing, indicating eNOS uncoupling. Autophagy markers such as LC3 II/I ratio, amount of Beclin1, as well as ULK1/Atg1 were increased during low SS exposure, whereas autophagic degradation of p62/SQSTM1 was markedly reduced, implying impaired autophagic flux. Interestingly, low SS-induced NO reduction could be reversed by rapamycin, WYE-354 or ATG5 overexpression vector via restoration of autophagic flux, but not by N-acetylcysteine or apocynin. eNOS uncoupling might be ascribed to autophagic flux blockade because phosphorylation of eNOS Thr495 by low SS or PMA stimulation was also regulated by autophagy. In contrast, eNOS acetylation was not found to be regulated by low SS and autophagy. Notably, although low SS had no influence on eNOS Ser1177 phosphorylation, whereas boosted eNOS Ser1177 phosphorylation by rapamycin were in favor of the eNOS recoupling through restoration of autophagic flux. Taken together, we reported a novel mechanism for regulation of eNOS uncoupling by low SS via autophagy-mediated eNOS phosphorylation, which is implicated in geometrical nature of atherogenesis. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Brian Eno Hollandi Festivali peakülaliseks

    Index Scriptorium Estoniae

    1999-01-01

    Inglise helilooja, videokunstnik ja muusikaprodutsent Brian Eno on 5.-26. juunini Amsterdamis toimuva avangardse Hollandi Festivali peakülaline, kelle videoinstallatsioon seatakse üles Stedelijki Muuseumis. Festivali programmist

  5. Vascular nitric oxide: Beyond eNOS

    Directory of Open Access Journals (Sweden)

    Yingzi Zhao

    2015-10-01

    Full Text Available As the first discovered gaseous signaling molecule, nitric oxide (NO affects a number of cellular processes, including those involving vascular cells. This brief review summarizes the contribution of NO to the regulation of vascular tone and its sources in the blood vessel wall. NO regulates the degree of contraction of vascular smooth muscle cells mainly by stimulating soluble guanylyl cyclase (sGC to produce cyclic guanosine monophosphate (cGMP, although cGMP-independent signaling [S-nitrosylation of target proteins, activation of sarco/endoplasmic reticulum calcium ATPase (SERCA or production of cyclic inosine monophosphate (cIMP] also can be involved. In the blood vessel wall, NO is produced mainly from l-arginine by the enzyme endothelial nitric oxide synthase (eNOS but it can also be released non-enzymatically from S-nitrosothiols or from nitrate/nitrite. Dysfunction in the production and/or the bioavailability of NO characterizes endothelial dysfunction, which is associated with cardiovascular diseases such as hypertension and atherosclerosis.

  6. Crataegus Special Extract WS 1442 Effects on eNOS and microRNA 155.

    Science.gov (United States)

    Wang, Xinwen; Liang, Yan; Shi, Jian; Zhu, Hao-Jie; Bleske, Barry E

    2018-04-16

    Increased expression of microRNA 155 (miR-155) results in a decrease in endothelial nitric oxide synthase (eNOS) expression and impaired endothelial function. Factors that have been shown to increase expression of miR-155 may be mitigated by WS 1442, an extract of hawthorn leaves and flowers ( Crataegus special extract) that contains a range of pharmacologically active substances including oligomeric proanthocyanidins and flavonoids. The purpose of this study is to determine the effect of WS 1442 on the expression of miR-155 and eNOS in the presence of tumor necrosis factor (TNF- α ). Human umbilical vein endothelial cells (HUVECs) were studied after the exposure to TNF- α , with or without simvastatin (positive control) and WS 1442. The expression levels of eNOS, phosphorylated eNOS, and miR-155 in the different HUVEC treatment groups were determined by western blot and quantitative real-time polymerase chain reaction, respectively. To evaluate the effect of WS 1442 on the eNOS activity, the medium and intracellular nitrate/nitrite (NO) concentrations were also analyzed using a colorimetric Griess assay kit. The results demonstrated that TNF- α upregulated miR-155 expression and decreased eNOS expression and NO concentrations. WS 1442 also increased miR-155 expression and decreased eNOS expression but, unlike TNF- α , increased phosphorylated eNOS expression and NO concentrations. Surprisingly, WS 1442 increased miR-155 expression; however, WS 1442 mitigated the overall negative effect of miR-155 on decreasing eNOS expression by increasing expression of phosphorylated eNOS and resulting in an increase in NO concentrations. In the setting where miR-155 may be expressed, WS 1442 may offer vascular protection by increasing the expression of phosphorylated eNOS. Georg Thieme Verlag KG Stuttgart · New York.

  7. Association between nucleotide mutation of eNOS gene and serum ...

    African Journals Online (AJOL)

    Various mutation on endothelial nitric oxide synthase (eNOs) gene cause reduced production of NO, the expansion factor (VEF) and may accelerate the process of atherosclerosis. The study was designed to investigate the frequency of T-786C polymorphism of the gene or nucleotide mutation of eNOS gene in patients ...

  8. Introduction of in vitro transcribed ENO1 mRNA into neuroblastoma cells induces cell death

    International Nuclear Information System (INIS)

    Ejeskär, Katarina; Krona, Cecilia; Carén, Helena; Zaibak, Faten; Li, Lingli; Martinsson, Tommy; Ioannou, Panayiotis A

    2005-01-01

    Neuroblastoma is a solid tumour of childhood often with an unfavourable outcome. One common genetic feature in aggressive tumours is 1p-deletion. The α-enolase (ENO1) gene is located in chromosome region 1p36.2, within the common region of deletion in neuroblastoma. One alternative translated product of the ENO1 gene, known as MBP-1, acts as a negative regulator of the c-myc oncogene, making the ENO1 gene a candidate as a tumour suppressor gene. Methods used in this study are transfection of cDNA-vectors and in vitro transcribed mRNA, cell growth assay, TUNEL-assay, real-time RT-PCR (TaqMan) for expression studies, genomic sequencing and DHPLC for mutation detection. Here we demonstrate that transfection of ENO1 cDNA into 1p-deleted neuroblastoma cell lines causes' reduced number of viable cells over time compared to a negative control and that it induces apoptosis. Interestingly, a similar but much stronger dose-dependent reduction of cell growth was observed by transfection of in vitro transcribed ENO1 mRNA into neuroblastoma cells. These effects could also be shown in non-neuroblastoma cells (293-cells), indicating ENO1 to have general tumour suppressor activity. Expression of ENO1 is detectable in primary neuroblastomas of all different stages and no difference in the level of expression can be detected between 1p-deleted and 1p-intact tumour samples. Although small numbers (11 primary neuroblastomas), there is some evidence that Stage 4 tumours has a lower level of ENO1-mRNA than Stage 2 tumours (p = 0.01). However, mutation screening of 44 primary neuroblastomas of all different stages, failed to detect any mutations. Our studies indicate that ENO1 has tumour suppressor activity and that high level of ENO1 expression has growth inhibitory effects

  9. A central role of eNOS in the protective effect of wine against metabolic syndrome.

    Science.gov (United States)

    Leighton, Federico; Miranda-Rottmann, Soledad; Urquiaga, Inés

    2006-01-01

    The positive health effects derived from moderate wine consumption are pleiotropic. They appear as improvements in cardiovascular risk factors such as plasma lipids, haemostatic mechanisms, endothelial function and antioxidant defences. The active principles would be ethanol and mainly polyphenols. Results from our and other laboratories support the unifying hypothesis that the improvements in risk factors after red wine consumption are mediated by endothelial nitric oxide synthase (eNOS). Many genes are involved, but the participation of eNOS would be a constant feature. The metabolic syndrome is a cluster of metabolic risk factors associated with high risk of cardiovascular disease (CVD). The National Cholesterol Education Programmmes Adult Treatment Panel III (NCEPATP III) clinical definition of the metabolic syndrome requires the presence of at least three risk factors, from among abdominal obesity, high plasma triacylglycerols, low plasma HDL, high blood pressure and high fasting plasma glucose. The molecular mechanisms responsible for the metabolic syndrome are not known. Since metabolic syndrome apparently affects 10-30% of the population in the world, research on its pathogenesis and control is needed. The recent finding that eNOS knockout mice present a cluster of cardiovascular risk factors comparable to those of the metabolic syndrome suggests that defects in eNOS function may cause human metabolic syndrome. These mice are hypertensive, insulin resistant and dyslipidemic. Further support for a pathogenic role of eNOS comes from the finding in humans that eNOS polymorphisms associate with insulin resistance and diabetes, with hypertension, with inflammatory and oxidative stress markers and with albuminuria. So, the data sustain the hypothesis that eNOS enhancement should reduce metabolic syndrome incidence and its consequences. Therefore red wine, since it enhances eNOS function, should be considered as a potential tool for the control of metabolic

  10. Circulating Blood eNOS Contributes to the Regulation of Systemic Blood Pressure and Nitrite Homeostasis

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    Wood, Katherine C.; Cortese-Krott, Miriam M.; Kovacic, Jason C.; Noguchi, Audrey; Liu, Virginia B.; Wang, Xunde; Raghavachari, Nalini; Boehm, Manfred; Kato, Gregory J.; Kelm, Malte; Gladwin, Mark T.

    2013-01-01

    Objective Mice genetically deficient in endothelial nitric oxide synthase (eNOS−/−) are hypertensive with lower circulating nitrite levels, indicating the importance of constitutively produced nitric oxide (NO•) to blood pressure regulation and vascular homeostasis. While the current paradigm holds that this bioactivity derives specifically from expression of eNOS in endothelium, circulating blood cells also express eNOS protein. A functional red cell eNOS that modulates vascular NO• signaling has been proposed. Approach and Results To test the hypothesis that blood cells contribute to mammalian blood pressure regulation via eNOS-dependent NO• generation, we cross-transplanted WT and eNOS−/− mice, producing chimeras competent or deficient for eNOS expression in circulating blood cells. Surprisingly, we observed a significant contribution of both endothelial and circulating blood cell eNOS to blood pressure and systemic nitrite levels, the latter being a major component of the circulating NO• reservoir. These effects were abolished by the NOS inhibitor L-NAME and repristinated by the NOS substrate L-Arginine, and were independent of platelet or leukocyte depletion. Mouse erythrocytes were also found to carry an eNOS protein and convert 14C-Arginine into 14C-Citrulline in a NOS-dependent fashion. Conclusions These are the first studies to definitively establish a role for a blood borne eNOS, using cross transplant chimera models, that contributes to the regulation of blood pressure and nitrite homeostasis. This work provides evidence suggesting that erythrocyte eNOS may mediate this effect. PMID:23702660

  11. Activation of Endothelial Nitric Oxide (eNOS Occurs through Different Membrane Domains in Endothelial Cells.

    Directory of Open Access Journals (Sweden)

    Jason Tran

    Full Text Available Endothelial cells respond to a large range of stimuli including circulating lipoproteins, growth factors and changes in haemodynamic mechanical forces to regulate the activity of endothelial nitric oxide synthase (eNOS and maintain blood pressure. While many signalling pathways have been mapped, the identities of membrane domains through which these signals are transmitted are less well characterized. Here, we manipulated bovine aortic endothelial cells (BAEC with cholesterol and the oxysterol 7-ketocholesterol (7KC. Using a range of microscopy techniques including confocal, 2-photon, super-resolution and electron microscopy, we found that sterol enrichment had differential effects on eNOS and caveolin-1 (Cav1 colocalisation, membrane order of the plasma membrane, caveolae numbers and Cav1 clustering. We found a correlation between cholesterol-induced condensation of the plasma membrane and enhanced high density lipoprotein (HDL-induced eNOS activity and phosphorylation suggesting that cholesterol domains, but not individual caveolae, mediate HDL stimulation of eNOS. Vascular endothelial growth factor (VEGF-induced and shear stress-induced eNOS activity was relatively independent of membrane order and may be predominantly controlled by the number of caveolae on the cell surface. Taken together, our data suggest that signals that activate and phosphorylate eNOS are transmitted through distinct membrane domains in endothelial cells.

  12. Aspiration toward geothermal energy utilization in regional development plan. Part 6. ; Hydrothermal fluid utilization business in Matsuo-mura of Iwate prefecture. Chiiki keikaku ni okeru 'chinetsu riyo' eno hofu. 6. ; Iwateken Matsuomura no chinetsu nessui riyo jigyo

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    Otobe, Y; Furutate, E

    1992-10-31

    Twenty six years have passed since the first geothermal power station was constructed in Matsuo-mura of Iwate Prefecture, Japan. This paper describes the history, the present situation and the future conception of the geothermal energy utilization in this village. This village includes Hachimantai of a vantage ground in the center and has the gross area of 233.8km[sup 2], the annual average temperature of 8.3 centigrade and the continuous snow cover period of about 100 days. The hot water leading facility was cooperatively constructed by Japan Metals and Chemicals, Hachimantai Hot Spring Development and Matsuo-mura. The total working expense is 539.3 million yen. Hot water sources are the condensate from the condenser of geothermal power plant and hot spring. This mixed hot water of 4.3 t/min is led to respective facilities. The hot water supplying channel has the length of 12.8km from the power station through the Hachimantai hot spring resort, Kamiyogi to Takaishino. Respective total areas of greenhouses using hydrothermal fluid in both districts are 1,075ha and the inlet temperature of hot water is 60 centigrade and kinds of crop are 5 like green pepper and others. Takaishino agricultural park has selected flower and ornamental plant culture such as poppy anemone, stock and statice which are suitable for this district of low temperature and insufficient sunshine. The planted area is 10,700m[sup 2]. 2 refs., 9 figs., 4 tabs.

  13. Mild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis.

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    Cerqueira, Fernanda M; Laurindo, Francisco R M; Kowaltowski, Alicia J

    2011-03-31

    Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR). Since treatment of mice with dinitrophenol (DNP) promotes health and lifespan benefits similar to those observed in CR, we hypothesized that it could also impact biogenesis. We found that DNP and CR increase citrate synthase activity, PGC-1α, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO• products. In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals. Overall, our results indicate that systemic mild uncoupling activates eNOS and Akt-dependent pathways leading to mitochondrial biogenesis.

  14. Mild mitochondrial uncoupling and calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis.

    Directory of Open Access Journals (Sweden)

    Fernanda M Cerqueira

    2011-03-01

    Full Text Available Enhanced mitochondrial biogenesis promoted by eNOS activation is believed to play a central role in the beneficial effects of calorie restriction (CR. Since treatment of mice with dinitrophenol (DNP promotes health and lifespan benefits similar to those observed in CR, we hypothesized that it could also impact biogenesis. We found that DNP and CR increase citrate synthase activity, PGC-1α, cytochrome c oxidase and mitofusin-2 expression, as well as fasting plasma levels of NO• products. In addition, eNOS and Akt phosphorylation in skeletal muscle and visceral adipose tissue was activated in fasting CR and DNP animals. Overall, our results indicate that systemic mild uncoupling activates eNOS and Akt-dependent pathways leading to mitochondrial biogenesis.

  15. Tidal breath eNO measurements in a cohort of unsedated hospitalized neonates-A method validation

    DEFF Research Database (Denmark)

    Schmidt, Birgitte J; Reim, Pauline S; Jensen, Andreas K

    2018-01-01

    to validate clinically feasible longitudinal online tidal eNO and V'NO in a real-life birth cohort of un-sedated, hospitalized preterm, and term neonates. METHOD: We included 149 newborns, GA 28-42 weeks. Each scheduled for six repeated, non-invasive, on-line eNO measurements with Ecomedics CLD 88sp and NO...

  16. Orthodontic force stimulates eNOS and iNOS in rat osteocytes

    NARCIS (Netherlands)

    Tan, S.D.; Xie, R.; Klein Nulend, J.; van Rheden, R.E.; Bronckers, A.L.J.J.; Kuijpers-Jagtman, A.M.; Von den Hoff, J.W.; Maltha, J.C.

    2009-01-01

    Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these

  17. Orthodontic force stimulates eNOS and iNOS in rat osteocytes.

    NARCIS (Netherlands)

    Tan, S.D.; Xie, R.; Klein-Nulend, J.; Rheden, R.E.M. van; Bronckers, A.L.; Kuijpers-Jagtman, A.M.; Hoff, J.W. Von den; Maltha, J.C.

    2009-01-01

    Mechanosensitive osteocytes are essential for bone remodeling. Nitric oxide, an important regulator of bone remodeling, is produced by osteocytes through the activity of constitutive endothelial nitric oxide synthase (eNOS) or inducible nitric oxide synthase (iNOS). We hypothesized that these

  18. Association between nucleotide mutation of eNOS gene and serum ...

    African Journals Online (AJOL)

    Galaxy

    2013-05-15

    May 15, 2013 ... spasm among Japanese (Nakayama et al., 1999; Casas et al., 2006). It is believed that these mutations might result in altered NO metabolism and impaired .... ship between T-786C mutation of eNOS gene and CAD specifically in the Iranian population. To our knowledge, this polymorphism has never been ...

  19. Association of eNOS and HSP70 gene polymorphisms with glaucoma in Pakistani cohorts.

    NARCIS (Netherlands)

    Ayub, H.; Khan, M.I.; Micheal, S.; Akhtar, F.; Ajmal, M.; Shafique, S.; Ali, S.H.; Hollander, A.I. den; Ahmed, A.; Qamar, R.

    2010-01-01

    PURPOSE: To investigate the involvement of stress-regulating genes, endothelial nitric oxide synthase (eNOS) and heat shock protein 70 (HSP70) with primary open angle glaucoma (POAG) and primary closed angle glaucoma (PCAG). METHODS: POAG and PCAG patients recruited from different areas of Pakistan

  20. A meta-analysis of eNOS and ACE gene polymorphisms and risk of pre-eclampsia in women.

    Science.gov (United States)

    Shaik, A P; Sultana, A; Bammidi, V K; Sampathirao, K; Jamil, K

    2011-10-01

    A meta-analyses of endothelial nitric oxide synthase (eNOS) and angiotensin-converting enzyme (ACE) gene polymorphisms in pre-eclampsia was performed. We shortlisted 33 studies (17 for ACE; 16 for eNOS gene polymorphisms), of which 29 articles (16 for ACE and 15 for eNOS) were analysed. Overall, 1,620 cases with pre-eclampsia and 2,158 controls were analysed for intron 16 insertion-deletion polymorphism in ACE gene. A total of 1,610 subjects with pre-eclampsia and 2,875 controls were analysed for the Glu298Asp in eNOS gene. Overall, the random-effects odds ratio (OR) with Glu298Asp in eNOS gene was 0.958 (95% confidence intervals, CI 0.747-1.228, p > 0.05), and for the insertion-deletion/ACE polymorphism was 0.987 (95% CI 0.698-1.395, p > 0.05). Significant heterogeneity was observed in the studies that evaluated polymorphisms in ACE (Q value = 55.6; I(2) = 73; p value = 0.000); and eNOS (Q value = 37.2; I(2) = 62.4; p value = 0.001) polymorphisms. No significant risk of pre-eclampsia was observed in both eNOS and ACE genes with these polymorphisms.

  1. Gender, exercise training, and eNOS expression in porcine skeletal muscle arteries.

    Science.gov (United States)

    Laughlin, M Harold; Welshons, Wade V; Sturek, Michael; Rush, James W E; Turk, James R; Taylor, Julia A; Judy, Barbara M; Henderson, Kyle K; Ganjam, V K

    2003-07-01

    Our purpose was to determine the effects of gender and exercise training on endothelial nitric oxide synthase (eNOS) and superoxide dismutase (SOD) protein content of porcine skeletal muscle arteries and to evaluate the role of 17beta-estradiol (E2) in these effects. We measured eNOS and SOD content with immunoblots and immunohistochemistry in femoral and brachial arteries of trained and sedentary male and female pigs and measured estrogen receptor (ER) mRNA and alpha-ER and beta-ER protein in aortas of male and female pigs. Results indicate that female arteries contain more eNOS than male arteries and that exercise training increases eNOS content independent of gender. Male and female pigs expressed similar levels of alpha-ER mRNA and protein and similar amounts beta-ER protein in their arteries. E2 concentrations as measured by RIA were 180 +/- 34 pg/ml in male sera and approximately 5 pg/ml in female sera, and neither was changed by training. However, bioassay indicated that biologically active estrogen equivalent to only 35 +/- 5 pg/ml was present in male sera. E2 in female pigs, whether measured by RIA or bioassay, was approximately 24 pg/ml at peak estrous and 2 pg/ml on day 5 diestrus. The free fraction of E2 in sera did not explain the low measurements, relative to RIA, of E2. We conclude that 1). gender has significant influence on eNOS and SOD content of porcine skeletal muscle arteries; 2). the effects of gender and exercise training vary among arteries of different anatomic origin; 3). male sera contains compounds that cause RIA to overestimate circulating estrogenic activity; and 4). relative to human men, the male pig is not biologically estrogenized by high levels of E2 reported by RIA, whereas in female pigs E2 levels are lower than in the blood of human women.

  2. Activation of eNOS in endothelial cells exposed to ionizing radiation involves components of the DNA damage response pathway

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    Nagane, Masaki; Yasui, Hironobu; Sakai, Yuri; Yamamori, Tohru [Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818 (Japan); Niwa, Koichi [Laboratory of Biochemistry, Department of Food and Cosmetic Science, Faculty of Bioindustry, Tokyo University of Agriculture, Abashiri 099-2493 (Japan); Hattori, Yuichi [Department of Molecular and Medical Pharmacology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194 (Japan); Kondo, Takashi [Department of Radiological Sciences, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama 930-0194 (Japan); Inanami, Osamu, E-mail: inanami@vetmed.hokudai.ac.jp [Laboratory of Radiation Biology, Department of Environmental Veterinary Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060-0818 (Japan)

    2015-01-02

    Highlights: • eNOS activity is increased in BAECs exposed to X-rays. • ATM is involved in this increased eNOS activity. • HSP90 modulates the radiation-induced activation of ATM and eNOS. - Abstract: In this study, the involvement of ataxia telangiectasia mutated (ATM) kinase and heat shock protein 90 (HSP90) in endothelial nitric oxide synthase (eNOS) activation was investigated in X-irradiated bovine aortic endothelial cells. The activity of nitric oxide synthase (NOS) and the phosphorylation of serine 1179 of eNOS (eNOS-Ser1179) were significantly increased in irradiated cells. The radiation-induced increases in NOS activity and eNOS-Ser1179 phosphorylation levels were significantly reduced by treatment with either an ATM inhibitor (Ku-60019) or an HSP90 inhibitor (geldanamycin). Geldanamycin was furthermore found to suppress the radiation-induced phosphorylation of ATM-Ser1181. Our results indicate that the radiation-induced eNOS activation in bovine aortic endothelial cells is regulated by ATM and HSP90.

  3. Towards unification of the Vorticity Confinement and Shock Capturing (TVD and ENO/WENO) methods

    Science.gov (United States)

    Sidilkover, David

    2018-04-01

    New multidimensional extensions of the TVD and finite difference ENO/WENO methods for the compressible flow equations are proposed. The novelty of the approach is in the discretization schemes that acquire by means of a single mechanism both shock-capturing and vorticity confinement capabilities. Thus, the new method can be interpreted as a unification of the two methodologies, intended initially for different purposes.

  4. Morus alba extract modulates blood pressure homeostasis through eNOS signaling.

    Science.gov (United States)

    Carrizzo, Albino; Ambrosio, Mariateresa; Damato, Antonio; Madonna, Michele; Storto, Marianna; Capocci, Luca; Campiglia, Pietro; Sommella, Eduardo; Trimarco, Valentina; Rozza, Francesco; Izzo, Raffaele; Puca, Annibale A; Vecchione, Carmine

    2016-10-01

    Morus alba is a promising phytomedicine cultivated in oriental countries that is extensively used to prevent and treat various cardiovascular problems. To date, despite its beneficial effects, the molecular mechanisms involved remain unclear. Thus, we investigate the vascular and haemodynamic effects of Morus alba extract in an experimental model focusing our attention on the molecular mechanisms involved. Through vascular reactivity studies, we demonstrate that Morus alba extract evokes endothelial vasorelaxation through a nitric oxide-dependent pathway. Our molecular analysis highlights an increase in endothelial nitric oxide synthase (eNOS) phosphorylation. In vivo administration of Morus alba extract reduces blood pressure levels exclusively in wild-type mice, whereas it fails to evoke any haemodynamic effects in eNOS-deficient mice. Molecular analyses revealed that its beneficial action on vasculature is mediated by the activation of two important proteins that act as stress sensors and chaperones: PERK and heat shock protein 90. Finally, Morus alba extract exerts antihypertensive action in an experimental model of arterial hypertension. Through its action on eNOS signaling, Morus alba extract could act as a food supplement for the regulation of cardiovascular system, mainly in clinical conditions characterized by eNOS dysfunction, such as arterial hypertension. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. A novel multiplex PCR-RFLP method for simultaneous detection of the MTHFR 677 C > T, eNOS +894 G > T and - eNOS -786 T > C variants among Malaysian Malays

    Directory of Open Access Journals (Sweden)

    Loo Keat

    2012-05-01

    Full Text Available Abstract Background Hyperhomocysteinemia as a consequence of the MTHFR 677 C > T variant is associated with cardiovascular disease and stroke. Another factor that can potentially contribute to these disorders is a depleted nitric oxide level, which can be due to the presence of eNOS +894 G > T and eNOS −786 T > C variants that make an individual more susceptible to endothelial dysfunction. A number of genotyping methods have been developed to investigate these variants. However, simultaneous detection methods using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP analysis are still lacking. In this study, a novel multiplex PCR-RFLP method for the simultaneous detection of MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C variants was developed. A total of 114 healthy Malay subjects were recruited. The MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C variants were genotyped using the novel multiplex PCR-RFLP and confirmed by DNA sequencing as well as snpBLAST. Allele frequencies of MTHFR 677 C > T and eNOS +894 G > T and eNOS −786 T > C were calculated using the Hardy Weinberg equation. Methods The 114 healthy volunteers were recruited for this study, and their DNA was extracted. Primer pair was designed using Primer 3 Software version 0.4.0 and validated against the BLAST database. The primer specificity, functionality and annealing temperature were tested using uniplex PCR methods that were later combined into a single multiplex PCR. Restriction Fragment Length Polymorphism (RFLP was performed in three separate tubes followed by agarose gel electrophoresis. PCR product residual was purified and sent for DNA sequencing. Results The allele frequencies for MTHFR 677 C > T were 0.89 (C allele and 0.11 (T allele; for eNOS +894 G > T, the allele frequencies were 0.58 (G allele and 0.43 (T allele; and for eNOS −786 T > C, the allele

  6. ENO1 promotes tumor proliferation and cell adhesion mediated drug resistance (CAM-DR) in Non-Hodgkin's Lymphomas

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Xinghua; Miao, Xiaobing; Wu, Yaxun; Li, Chunsun; Guo, Yan; Liu, Yushan; Chen, Yali; Lu, Xiaoyun [Department of Pathology, Affiliated Cancer Hospital of Nantong University, 30 North Tongyang Road, Pingchao, Nantong 226361, Jiangsu (China); Wang, Yuchan, E-mail: wangyuchannt@126.com [Department of Pathogen and Immunology, Medical College, Nantong University, 19 Qixiu Road, Nantong 226001, Jiangsu (China); He, Song, E-mail: hesongnt@126.com [Department of Pathology, Affiliated Cancer Hospital of Nantong University, 30 North Tongyang Road, Pingchao, Nantong 226361, Jiangsu (China)

    2015-07-15

    Enolases are glycolytic enzymes responsible for the ATP-generated conversion of 2-phosphoglycerate to phosphoenolpyruvate. In addition to the glycolytic function, Enolase 1 (ENO1) has been reported up-regulation in several tumor tissues. In this study, we investigated the expression and biologic function of ENO1 in Non-Hodgkin's Lymphomas (NHLs). Clinically, by western blot analysis we observed that ENO1 expression was apparently higher in diffuse large B-cell lymphoma than in the reactive lymphoid tissues. Subsequently, immunohistochemical staining of 144 NHLs suggested that the expression of ENO1 was significantly lower in the indolent lymphomas compared with the progressive lymphomas. Further, we identified ENO1 as an independent prognostic factor, and it was significantly correlated with overall survival of NHL patients. In addition, we found that ENO1 could promote cell proliferation, regulate cell cycle associated gene and PI3K/AKT signaling pathway in NHLs. Finally, we verified that ENO1 participated in the process of lymphoma cell adhesion mediated drug resistance (CAM-DR). Adhesion to FN or HS5 cells significantly protected OCI-Ly8 and Daudi cells from cytotoxicity compared with those cultured in suspension, and these effects were attenuated when transfected with ENO1-siRNA. Based on the study, we propose that inhibition of ENO1 expression may be a novel strategy for therapy for NHLs patients, and it may be a target for drug resistance. - Highlights: • ENO1 expression is reversely correlated with clinical outcomes of patients with NHLs. • ENO1 promotes the proliferation of NHL cells. • ENO1 regulates cell adhesion mediated drug resistance.

  7. KONSUMSI MIKRONUTRIEN DAN EKSPRESI GEN eNOS3 ALEL INTRO 4a4b PADA PENDERITA HIPERTENSI ETNIK MINANGKABAU

    Directory of Open Access Journals (Sweden)

    Delmi Sulastri

    2011-05-01

    Full Text Available AbstrakGen eNOS3 varian intron 4a4b merupakan salah satu gen yang berhubungan dengan kejadian hipertensi esensial. Kemampuan Gen eNOS3 varian ini untuk mensintesis enzim nitric oxide synthase (NOS berkurang sehingga sintesis Nitric oxide (NO menurun. Senyawa NO adalah suatu senyawa vasoaktif yang menyebabkan vasodilatasi pembuluh darah.Penelitian pada subjek hipertensi dan normotensi berusia 30-65 tahun bertujuan untuk melihat pengaruh mikronutrien terhadap ekspresi gen eNOS3 alel intron 4a4b. 130 subjek, diwawancara pola makannya lalu dilakukan analisis asupan mikronutrien, gen eNOS3, serta kadar NO plasma. Data yang diperoleh dianalisis menggunakan uji T dan chi-square.Kadar NO plasma penderita hipertensi adalah 26.91 + 15.40 μM/L dan normotensi 25.79 + 15.04 μM/L. 55.5% subjek hipertensi memiliki gen eNOS3 varian intron 4b dan 69% subjek normotensi mempunyai varian intron 4a4b. Kadar NO plasma rendah, (66.7% ditemukan pada subjek hipertensi dengan varian intron 4b. Tidak terdapat hubungan bermakna asupan mikronutrien dengan kadar NO plasma pada subjek hipertensi.Hasil ini tidak mendukung pengaruh konsumsi mikronutrien terhadap kadar NO plasma pada penderita hipertensi dengan gen eNOS3 varian intron 4a4b.Kata Kunci : hipertensi esensial, gen eNOS3, kadar NO plasmaAbstracteNOS 3 gene intron 4a4b allel is one of the important genes which is related to hypertesion essensial. This gene expresses the nitric oxide synthase (NOS enzyme which regulates the synthesis of Nitric oxide (NO in human body. NO causes vasodilatation, which decreases peripheral resistant and blood pressure.A research has been done based on cross sectional study on hypertension patients and those with normal blood pressure in the range of 30-65 years old. The main of this research is to evaluate the influence of micronutrient consumption on eNOS3 gene intron 4a4b allel expression in hypertension subjects in Minangkabau ethnicity. 130 subjects interviewed about micronutrient

  8. Disruption of COX-2 and eNOS does not confer protection from cardiovascular failure in lipopolysaccharide-treated conscious mice and isolated vascular rings

    DEFF Research Database (Denmark)

    Stæhr, Mette; Madsen, Kirsten; Vanhoutte, Paul M

    2011-01-01

    (NS 398), disruption of COX-2, endothelium removal, or eNOS deletion (eNOS(-/-)) did not improve vascular reactivity after LPS, while the NO synthase blockers 1400W and N(G)-nitro-l-arginine methyl ester prevented loss of tone. COX-2 and eNOS activities are not necessary for LPS-induced decreases...... in blood pressure, heart rate, and vascular reactivity. Inducible NOS activity appears crucial. COX-2 and eNOS are not obvious therapeutic targets for cardiovascular rescue during gram-negative endotoxemic shock....

  9. Alpha-enolase (ENO1 controls alpha v/beta 3 integrin expression and regulates pancreatic cancer adhesion, invasion, and metastasis

    Directory of Open Access Journals (Sweden)

    Moitza Principe

    2017-01-01

    Full Text Available Abstract Background We have previously shown that in pancreatic ductal adenocarcinoma (PDA cells, the glycolytic enzyme alpha-enolase (ENO1 also acts as a plasminogen receptor and promotes invasion and metastasis formation. Moreover, ENO1 silencing in PDA cells induces oxidative stress, senescence and profoundly modifies PDA cell metabolism. Although anti-ENO1 antibody inhibits PDA cell migration and invasion, little is known about the role of ENO1 in regulating cell-cell and cell-matrix contacts. We therefore investigated the effect of ENO1 silencing on the modulation of cell morphology, adhesion to matrix substrates, cell invasiveness, and metastatic ability. Methods The membrane and cytoskeleton modifications that occurred in ENO1-silenced (shENO1 PDA cells were investigated by a combination of confocal microscopy and atomic force microscopy (AFM. The effect of ENO1 silencing was then evaluated by phenotypic and functional experiments to identify the role of ENO1 in adhesion, migration, and invasion, as well as in senescence and apoptosis. The experimental results were then validated in a mouse model. Results We observed a significant increase in the roughness of the cell membrane due to ENO1 silencing, a feature associated with an impaired ability to migrate and invade, along with a significant downregulation of proteins involved in cell-cell and cell-matrix adhesion, including alpha v/beta 3 integrin in shENO1 PDA cells. These changes impaired the ability of shENO1 cells to adhere to Collagen I and IV and Fibronectin and caused an increase in RGD-independent adhesion to vitronectin (VN via urokinase plasminogen activator receptor (uPAR. Binding of uPAR to VN triggers integrin-mediated signals, which result in ERK1-2 and RAC activation, accumulation of ROS, and senescence. In shENO1 cancer cells, the use of an anti-uPAR antibody caused significant reduction of ROS production and senescence. Overall, a decrease of in vitro and in vivo cell

  10. Enhancing eNOS activity with simultaneous inhibition of IKKβ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice.

    Science.gov (United States)

    Krishnan, Manickam; Janardhanan, Preethi; Roman, Linda; Reddick, Robert L; Natarajan, Mohan; van Haperen, Rien; Habib, Samy L; de Crom, Rini; Mohan, Sumathy

    2015-10-01

    The balance of nitric oxide (NO) versus superoxide generation has a major role in the initiation and progression of endothelial dysfunction. Under conditions of high glucose, endothelial nitric oxide synthase (eNOS) functions as a chief source of superoxide rather than NO. In order to improve NO bioavailability within the vessel wall in type-1 diabetes, we investigated treatment strategies that improve eNOS phosphorylation and NO-dependent vasorelaxation. We evaluated methods to increase the eNOS activity by (1) feeding Ins2(Akita) spontaneously diabetic (type-1) mice with l-arginine in the presence of sepiapterin, a precursor of tetrahydrobiopterin; (2) preventing eNOS/NO deregulation by the inclusion of inhibitor kappa B kinase beta (IKKβ) inhibitor, salsalate, in the diet regimen in combination with l-arginine and sepiapterin; and (3) independently increasing eNOS expression to improve eNOS activity and associated NO production through generating Ins2(Akita) diabetic mice that overexpress human eNOS predominantly in vascular endothelial cells. Our results clearly demonstrated that diet supplementation with l-arginine, sepiapterin along with salsalate improved phosphorylation of eNOS and enhanced vasorelaxation of thoracic/abdominal aorta in type-1 diabetic mice. More interestingly, despite the overexpression of eNOS, the in-house generated transgenic eNOS-GFP (TgeNOS-GFP)-Ins2(Akita) cross mice showed an unanticipated effect of reduced eNOS phosphorylation and enhanced superoxide production. Our results demonstrate that enhancement of endogenous eNOS activity by nutritional modulation is more beneficial than increasing the endogenous expression of eNOS by gene therapy modalities.

  11. Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity.

    Directory of Open Access Journals (Sweden)

    Shubha Murthy

    Full Text Available The multifunctional Ca2+/calmodulin-dependent protein kinase II (CaMKII is a serine/threonine kinase important in transducing intracellular Ca2+ signals. While in vitro data regarding the role of CaMKII in the regulation of endothelial nitric oxide synthase (eNOS are contradictory, its role in endothelial function in vivo remains unknown. Using two novel transgenic models to express CaMKII inhibitor peptides selectively in endothelium, we examined the effect of CaMKII on eNOS activation, NO production, vasomotor tone and blood pressure. Under baseline conditions, CaMKII activation was low in the aortic wall. Consistently, systolic and diastolic blood pressure, heart rate and plasma NO levels were unaltered by endothelial CaMKII inhibition. Moreover, endothelial CaMKII inhibition had no significant effect on NO-dependent vasodilation. These results were confirmed in studies of aortic rings transduced with adenovirus expressing a CaMKII inhibitor peptide. In cultured endothelial cells, bradykinin treatment produced the anticipated rapid influx of Ca2+ and transient CaMKII and eNOS activation, whereas CaMKII inhibition blocked eNOS phosphorylation on Ser-1179 and dephosphorylation at Thr-497. Ca2+/CaM binding to eNOS and resultant NO production in vitro were decreased under CaMKII inhibition. Our results demonstrate that CaMKII plays an important role in transient bradykinin-driven eNOS activation in vitro, but does not regulate NO production, vasorelaxation or blood pressure in vivo under baseline conditions.

  12. Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis.

    Science.gov (United States)

    Musicki, Biljana; Bivalacqua, Trinity J; Champion, Hunter C; Burnett, Arthur L

    2014-02-01

    Sickle cell disease (SCD)-associated vasculopathy in the penis is characterized by aberrant nitric oxide and phosphodiesterase (PDE) 5 signaling, and by increased oxidative stress. Preliminary clinical trials show that continuous treatment with PDE5 inhibitor sildenafil unassociated with sexual activity decreases priapic activity in patients with SCD. However, the mechanism of its vasculoprotective effect in the penis remains unclear. We evaluated whether continuous administration of PDE5 inhibitor sildenafil promotes eNOS function at posttranslational levels and decreases superoxide-producing enzyme NADPH oxidase activity in the sickle cell mouse penis. SCD transgenic mice were used as an animal model of SCD. WT mice served as controls. Mice received treatment with the PDE5 inhibitor sildenafil (100 mg/kg/day) or vehicle for 3 weeks. eNOS phosphorylation on Ser-1177 (positive regulatory site), eNOS interactions with heat-shock protein 90 (HSP90) (positive regulator), phosphorylated AKT (upstream mediator of eNOS phosphorylation on Ser-1177), an NADPH oxidase catalytic subunit gp91(phox), and a marker of oxidative stress (4-hydroxy-2-nonenal [HNE]) were measured by Western blot. Effect of continuous sildenafil treatment on eNOS posttranslational activation, NADPH oxidase catalytic subunit, and oxidative stress in the penis of the sickle cell mouse. Continuous treatment with sildenafil reversed (P penis. Sildenafil treatment of WT mice did not affect any of these parameters. Our findings that sildenafil enhances eNOS activation and inhibits NADPH oxidase function in the sickle cell mouse penis offers a vasculoprotective molecular basis for the therapeutic effect of sildenafil in the penis in association with SCD. © 2013 International Society for Sexual Medicine.

  13. Partial deletion of eNOS gene causes hyperinsulinemic state, unbalance of cardiac insulin signaling pathways and coronary dysfunction independently of high fat diet.

    Directory of Open Access Journals (Sweden)

    Cecilia Vecoli

    Full Text Available Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD, affect peripheral vascular function and glucose metabolism. The relative role of eNOS gene, HFD and metabolic derangement on coronary function has not been fully elucidated. We test whether eNOS gene deficiency per se or in association with HFD modulates coronary function through mechanisms involving molecular pathways related to insulin signaling. Wild type (WT, eNOS-/- and eNOS+/- mice were studied. WT and eNOS+/- mice were fed with either standard or HF diet for 16 weeks and compared with standard diet fed eNOS-/-. Glucose and insulin tolerance tests were performed during the last week of diet. Coronary resistance (CR was measured at baseline and during infusions of acetylcholine (Ach or sodium-nitroprusside (SNP to evaluate endothelium-dependent or independent vasodilation, in the Langendorff isolated hearts. Cardiac expression of Akt and ERK genes as evaluation of two major insulin-regulated signaling pathways involved in the control of vascular tone were assessed by western blot. HFD-fed mice developed an overt diabetic state. Conversely, chow-fed genetically modified mice (in particular eNOS-/- showed a metabolic pattern characterized by normoglycemia and hyperinsulinemia with a limited degree of insulin resistance. CR was significantly higher in animals with eNOS gene deletions than in WT, independently of diet. Percent decrease in CR, during Ach infusion, was significantly lower in both eNOS-/- and eNOS+/- mice than in WT, independently of diet. SNP reduced CR in all groups except eNOS-/-. The cardiac ERK1-2/Akt ratio, increased in animals with eNOS gene deletions compared with WT, independently of diet. These results suggest that the eNOS genetic deficiency, associated or not with HFD, has a relevant effect on coronary vascular function, possibly mediated by increase in blood insulin levels and unbalance in insulin-dependent signaling in coronary vessels

  14. Environmental Aspects as Assessment Criteria in Municipal Heat Energy Decisions - Case of Eno Energy Cooperative

    Energy Technology Data Exchange (ETDEWEB)

    Puhakka, Asko [North Karelia Univ. of Applied Sciences, Joensuu (Finland)

    2006-07-15

    The aim of this paper is to provide information whether it is possible to consider the sustainable development perspectives in the decision making of the district energy decision. The new EU-directives concerning public procurements allow the use of environmental aspects as selection criteria. The focus here is on small-scale district heating systems and their fuel-supply chains. The comparable fuels included the analysis are forest chips, heavy fuel oil, light fuel oil and peat. The paper focuses to the concept of the sustainable development and establishes the indicators for ecological-, social- and economical aspects of the district heating. The indicators are utilized in the case study on the Eno Energy Cooperative. The equivalent CO{sub 2} emissions from the production and the combustion of the fuel, the employment impacts of the fuel production and the formation of the price of energy for the consumers are considered. After presenting the sustainable development indicators in the case of Eno Energy Cooperative, the investment models of heat entrepreneurship business are discussed. Finally, we also raise an attention into important aspects to be considered when establishing a local district heating scheme. The indicators used in this presentation show that the use of forest chips in energy production has positive effect through the reduced greenhouse gases. The use of wood in energy production also provides employment opportunities and is more favourable to consumers, because of the steady fuel price when compared to other alternative fuels.

  15. Vasoinhibins Prevent Bradykinin-Stimulated Endothelial Cell Proliferation by Inactivating eNOS via Reduction of both Intracellular Ca2+ Levels and eNOS Phosphorylation at Ser1179

    Directory of Open Access Journals (Sweden)

    Carmen Clapp

    2011-07-01

    Full Text Available Vasoinhibins, a family of antiangiogenic peptides derived from prolactin proteolysis, inhibit the vascular effects of several proangiogenic factors, including bradykinin (BK. Here, we report that vasoinhibins block the BK-induced proliferation of bovine umbilical vein endothelial cells. This effect is mediated by the inactivation of endothelial nitric oxide synthase (eNOS, as the NO donor DETA-NONOate reverted vasoinhibin action. It is an experimentally proven fact that the elevation of intracellular Ca2+ levels ([Ca2+]i upon BK stimulation activates eNOS, and vasoinhibins blocked the BK-mediated activation of phospholipase C and the formation of inositol 1,4,5-triphosphate leading to a reduced release of Ca2+ from intracellular stores. The [Ca2+]i rise evoked by BK also involves the influx of extracellular Ca2+ via canonical transient receptor potential (TRPC channels. Vasoinhibins likely interfere with TRPC-mediated Ca2+ entry since La3+, which is an enhancer of TRPC4 and TRPC5 channel activity, prevented vasoinhibins from blocking the stimulation by BK of endothelial cell NO production and proliferation, and vasoinhibins reduced the BK-induced increase of TRPC5 mRNA expression. Finally, vasoinhibins prevented the BK-induced phosphorylation of eNOS at Ser1179, a post-translational modification that facilitates Ca2+-calmodulin activation of eNOS. Together, our data show that vasoinhibins, by lowering NO production through the inhibition of both [Ca2+]i mobilization and eNOS phosphorylation, prevent the BK-induced stimulation of endothelial cell proliferation. Thus, vasoinhibins help to regulate BK effects on angiogenesis and vascular homeostasis.

  16. Effects of hyperbaric oxygen therapy in enhancing expressions of e-NOS, TNF-α and VEGF in wound healing

    Science.gov (United States)

    Susilo, Imam; Devi, Anita; Purwandhono, Azham; Hadi Warsito, Sunaryo

    2017-05-01

    Wound healing is a physiological process that occurs progressively through overlapping phases. Tissue oxygenation is an important part of the complex regulation for wound healing. Hyperbaric Oxygen (HBO) therapy is a method of increasing oxygen delivery to tissues. The therapy improves tissue oxygenation and stimulates the formation of H2O2 as a secondary messenger for Tumour Necrosis Factor alpha (TNF α), e-NOS, VEGF and Nuclear Factor Kappa Beta phosphorylation (NF-Kb) which play an important role in the rapid transcription of a wide variety of genes in response to extracellular stimuli. This study aims to determine the effects of Hyperbaric Oxygen therapy in enhancing the expressions of e-NOS, TNF-α, VEGF and wound healing. This study is an animal study with a ‘randomized control group of pre-test and post test design’ on 28 Wistar rats. Randomly, the rats were divided into 4 groups with 7 rats in each group. The HBO treatment group 1 received 5 sessions of HBO 2.4 ATA in 3 × 30 minutes; the HBO treatment group 2 received 10 sessions of HBO 2.4 ATA in 3 × 30 minutes; and each of the control groups were without HBO. Each of the 28 male rats were given a full thickness excisional wound of 1 × 1cm. Examinations of e-NOS, TNF-α, VEGF expressions and wound healing were performed on day-0 (pre-HBO) and day-5 HBO or on day-0 (pre-HBO) and day-10 HBO. The resultsshowthat the Hyperbaric Oxygen therapy can improve e-NOS (p=0.02), TNF-α (p= 0.02), VEGF expression (p=0.02) and wound healing (p=0.002) significantly in the provision of HBO 2.4 ATA for 3 × 30 minutes in 5 sessions over 5 consecutive days. While the 10 sessions of HBO 2.4 ATA for 3 × 30 minutes over 10 consecutive days only increase e-NOS (p=0.02), TNF-α (p=0.04), VEGF expression significantly (p=0.03) but do not improve wound healing significantly (p=0.3) compared with no HBO. The study concludes that HBO can improve the expressions of e-NOS, TNF-α, VEGF and wound healing in the provision of HBO

  17. Achievement report for fiscal 1998 on business auxiliary to New Sunshine Program. Hot water-aided power generation plant development (Development of deep-seated geothermal resources exploitation technology and development of deep-seated geothermal resources excavating technology); 1998 nendo new sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu, shinbu chinetsu shigen kussaku gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    In the general exploitation scheme, technological information is collected about cement overseas, DHM (down hole motor), etc. In the development of heat-resistant durable bits, an improved version of the 350 degrees C real bit manufactured in fiscal 1997 undergoes a test in a real bore, and is evaluated for its general performance. In the development of high-temperature cement slurries, the ultralow specific gravity cement slurry for casing cement developed in fiscal 1997 is subjected to evaluation. It is examined by chemical analysis and powder X-ray diffraction, and its fluidity, free water, rate of dehydration, and compression strength at 250 degrees C are measured. In a real bore test, a slurry of the optimum composition is prepared and then hardened, and the hardened body is kept exposed to geothermal environments for eight weeks. It is then found that the hardened body retains a compression strength of 70kgf/cm{sup 2}. In the development of a down hole motor, a scale model, real in diameter and shortened in length, is built of the motor section, and is tested in circulating water and oil at normal and high temperatures, and its behavior and performance are evaluated. (NEDO)

  18. Fiscal 1995 report on the results of the subsidy operation under the Sunshine Project on the development of a geothermal water use power plant, etc. Development of the deep geothermal resource collecting technology (development of the deep geothermal resource drilling technology); 1995 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu / shinbu chinetsu shigen kussaku gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The paper reported the results of the fiscal 1995 R and D on the development of deep geothermal resource collecting/drilling technology. In the design of a total development, the trend of technical development was examined of bits, cement and DHM overseas. Further, the simulational prediction was conducted in deep geothermal drilling. As to the development of element technology of hard high temperature strata drilling, the R and D of seal mechanism, bearing mechanism and cutter mechanism were carried out aiming at developing heat resistant/durable bits, and a bit was trially manufactured which was integrated with element parts selected by each element technology. Concerning the development of high temperature drilling mud, studies were made of the development of drilling mud materials, a mud system, etc. Relating to the development of high temperature cement slurry, the development was conducted of high temperature cement, dewatering adjusting agents, etc. As to the development of high accuracy much inclination drilling technology, in the development of high temperature use downhole motor, tests on heat resistance/durability were carried out in the mud of 12 kinds of high heat resistant stator materials. 175 figs., 137 tabs.

  19. Fiscal 1996 report on the results of the subsidy operation under the Sunshine Project on the development of a geothermal water use power plant, etc. Development of the deep geothermal resource collecting technology (development of the deep geothermal resource drilling technology); 1996 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu / shinbu chinetsu shigen kussaku gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The paper reported the results of the fiscal 1996 R and D on the development of deep geothermal resource collecting/drilling technology. In the design of a total development, the planned adjustment of actual well tests was conducted on bits and drilling mud at the time of drilling the exploration well of the Kakkonda area. As to the trend of overseas technology, examined was the developmental trend of high temperature type downhole motor products. In the development of hard high temperature strata drilling element technology, a drilling test was carried out on trially manufactured 300degC heat resistant/durable bits. In the development of high temperature drilling mud, drilling was done in the mud of thermally stable quality in the actual well experiment using the 300degC mud system. In the development of high temperature use cement and high temperature use cement slurry, a possibility was obtained of composing a slurry which has the targeted dewatering amount, compressive strength, and water permeability. In the development of high temperature downhole motor, data on characteristics of heat resistant stator materials were arranged in a relationship among the abrasion amount, thermal expansion amount and elastic recovery amount, and the database was obtained. 166 figs., 148 tabs.

  20. An Eulerian method for computation of multimaterial impact with ENO shock-capturing and sharp interfaces

    CERN Document Server

    Udaykumar, H S; Belk, D M; Vanden, K J

    2003-01-01

    A technique is presented for the numerical simulation of high-speed multimaterial impact. Of particular interest is the interaction of solid impactors with targets. The computations are performed on a fixed Cartesian mesh by casting the equations governing material deformation in Eulerian conservation law form. The advantage of the Eulerian setting is the disconnection of the mesh from the boundary deformation allowing for large distortions of the interfaces. Eigenvalue analysis reveals that the system of equations is hyperbolic for the range of materials and impact velocities of interest. High-order accurate ENO shock-capturing schemes are used along with interface tracking techniques to evolve sharp immersed boundaries. The numerical technique is designed to tackle the following physical phenomena encountered during impact: (1) high velocities of impact leading to large deformations of the impactor as well as targets; (2) nonlinear wave-propagation and the development of shocks in the materials; (3) modelin...

  1. Identification and Function Analysis of enolase Gene NlEno1 from Nilaparvata lugens (Stål) (Hemiptera:Delphacidae)

    Science.gov (United States)

    Wang, Wei-Xia; Li, Kai-Long; Chen, Yang; Lai, Feng-Xiang; Fu, Qiang

    2015-01-01

    The enolase [EC 4.2.1.11] is an essential enzyme in the glycolytic pathway catalyzing the conversion of 2-phosphoglycerate (2-PGE) to phosphoenolpyruvate (PEP). In this study, a full-length cDNA encoding α-enolase was cloned from rice brown planthopper (Nilaparvata lugens) and is provisionally designated as NlEno1. The cDNA sequence of NlEno1 was 1,851 bp with an open reading frame (ORF) of 1,305 bp and encoding 434 amino acids. The deduced protein shares high identity of 80–87% with ENO1-like protein from Hemiptera, Diptera, and Lepidoptera speices. The NlEno1 showed the highest mRNA expression level in hemolymph, followed by fat body, salivary gland, ovaries and egg, and showed trace mRNA levels in testis. The mRNA of NlEno1 showed up-regulated level in virulent N. lugens population Mudgo, IR56 and IR42 when compared with TN1 population. Injection of double-stranded RNA (dsRNA) of NlEno1 into the adults significantly down-regulated the NlEno1 mRNA level along with decreased eggs and offspring. Moreover, injection of NlEno1-dsRNA decreased mRNA level of Vitellogenin (Vg) gene. These results showed that the NlEno1, as a key glycolytic enzyme, may play roles in regulation of fecundity and adaptation of N. lugens to resistant rice varieties. PMID:26056319

  2. Endothelial dysfunction in children with obstructive sleep apnea is associated with epigenetic changes in the eNOS gene.

    Science.gov (United States)

    Kheirandish-Gozal, Leila; Khalyfa, Abdelnaby; Gozal, David; Bhattacharjee, Rakesh; Wang, Yang

    2013-04-01

    Obstructive sleep apnea (OSA) is a highly prevalent disorder that has been associated with an increased risk for cardiovascular morbidity, even in children. However, not all children with OSA manifest alterations in endothelial postocclusive hyperemia, an endothelial nitric oxide synthase (eNOS)-dependent response. Since expression of the eNOS gene is regulated by epigenetic mechanisms and OSA may cause epigenetic modifications such as DNA hypermethylation, we hypothesized that epigenetic modifications in the eNOS gene may underlie the differential vascular phenotypes in pediatric OSA. Age-, sex-, ethnicity-, and BMI-matched prepubertal children with polysomnographically confirmed OSA and either normal (OSAn) or abnormal (OSAab) postocclusive hyperemic responses, assessed as the time to attain peak reperfusion flow (Tmax) by laser Doppler flowmetry, were recruited. Blood genomic DNA was assessed for epigenetic modifications in the eNOS gene using pyrosequencing. Children with no evidence of OSA or endothelial dysfunction served as a control group. The study comprised 36 children with OSA (11 with OSAab and 25 with OSAn) and 35 children in the control group. Overall, the mean age was 7.5 ± 2.4 years, 65% were boys, and 30% were obese; mean apnea-hypopnea index was 18 ± 8.6/h of sleep for the children with OSA. Tmax was 66.7 ± 8.8 s in the OSAab group and 30.1 ± 8.3 s in the OSAn group (P < .001). Pyrosequencing of the proximal promoter region of the eNOS gene revealed no significant differences in six of the seven CpG sites. However, a CpG site located at position -171 (relative to transcription start site), approximating important transcriptional elements, displayed significantly higher methylation levels in the OSAab group as compared with the OSAn or control groups (81.5% ± 3.5%, 74.8% ± 1.4%, and 74.5% ± 1.7%, respectively; P < .001). eNOS mRNA expression levels were assessed in a separate group of children and were significantly reduced in the OSAab

  3. Estrogen Receptor Signaling and the PI3K/Akt Pathway Are Involved in Betulinic Acid-Induced eNOS Activation

    Directory of Open Access Journals (Sweden)

    Nicolas Hohmann

    2016-07-01

    Full Text Available Betulinic acid (BA is a naturally occurring pentacyclic triterpenoid with anti-inflammatory, antiviral and anti-cancer properties. Beneficial cardiovascular effects such as increased nitric oxide (NO production through enhancement of endothelial NO synthase (eNOS activity and upregulation of eNOS expression have been demonstrated for this compound. In the present study, immortalized human EA.hy 926 endothelial cells were incubated for up to 1 h with 1–100 µM BA and with the phosphatidylinositol-3-kinase (PI3K inhibitors LY294002 and wortmannin, or the estrogen receptor (ER antagonist ICI 182,780. Phosphorylation status of eNOS and total eNOS protein were analyzed by Western blotting using a serine 1177 phosphosite-specific antibody. Bioactive NO production was assessed by determination of cGMP content in rat lung fibroblasts (RFL-6 reporter cells. Short-term incubation of EA.hy 926 cells with BA resulted in eNOS phosphorylation at the serine 1177 residue in a concentration- and time-dependent manner with a half-maximal effective concentration of 0.57 µM. This was associated with an enhanced production of NO. BA-induced eNOS phosphorylation and NO production was completely blocked by pretreatment with ICI 182,780, and was attenuated by pretreatment with the PI3K inhibitors wortmannin and LY294002. These results indicate that fast non-genomic effects of ER with downstream signaling through the PI3K/Akt pathway and consecutive eNOS phosphorylation at serine 1177 are involved in BA-induced eNOS activation.

  4. Alteration in cardiac uncoupling proteins and eNOS gene expression following high-intensity interval training in favor of increasing mechanical efficiency

    OpenAIRE

    Fallahi, Ali Asghar; Shekarfroush, Shahnaz; Rahimi, Mostafa; Jalali, Amirhossain; Khoshbaten, Ali

    2016-01-01

    Objective(s): High-intensity interval training (HIIT) increases energy expenditure and mechanical energy efficiency. Although both uncoupling proteins (UCPs) and endothelial nitric oxide synthase (eNOS) affect the mechanical efficiency and antioxidant capacity, their effects are inverse. The aim of this study was to determine whether the alterations of cardiac UCP2, UCP3, and eNOS mRNA expression following HIIT are in favor of increased mechanical efficiency or decreased oxidative stress. Mat...

  5. FEATURES OF THE CLINICAL SIGNIFICANCE OF POLYMORPHIC VARIANTS OF ENOS AND AGTR2 GENES IN PATIENTS WITH CAD

    Directory of Open Access Journals (Sweden)

    A. L. Khokhlov

    2016-01-01

    Full Text Available Coronary heart disease (CHD is a major cause of mortality. Morphological substrate of CHD in most cases is atherosclerosis, which is based on structural genes polymorphism eNOS and AGTR2. The aim of the study was to study the prevalence of eNOS and AGTR2 genes in patients with coronary artery disease and the association of these genes with coronary heart disease. The study involved 187 patients aged 36 to 86 years (62,2±11,2 with different forms of CHD: stable and unstable angina, myocardial infarction and 45 people without CHD. Determination of gene polymorphisms was performed by real-time PCR analyzer of nucleic acids IQ 5 Bio-Rad. Statistical analysis was performed using Statistica 10.0. The study revealed a significant difference between the incidence of homozygous AA allelic variant gene AGTR2 group of patients with myocardial infarction and the comparison group; polymorphic variant AA AGTR2 gene is associated with earlier onset of coronary artery disease; It found that carriers of the polymorphic variant gene GA AGTR2 beginning statistically CHD occurred significantly later than in carriers of alleles GG and AA; age CHD debut TT allele carriers of the eNOS gene is associated with an earlier onset of the disease and statistically significantly different from the age of first CHD in carriers of alleles of polymorphic variants of GG and GT; revealed a positive correlation between the polymorphic allele AGTR2 gene with the presence of arterial hypertension in patients with coronary artery disease; It determined that the T allele carriers of the polymorphic gene eNOS is associated more early onset of hypertension, found the association of the polymorphic allele gene AGTR2 the need to use higher doses of ACE inhibitor — perindopril.

  6. Immunomodulatory effects of royal jelly on aorta CD3, CD68 and eNOS expression in hypercholesterolaemic rats

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    Amal Attia El-Morsy Ibrahim

    2014-08-01

    RJ administration (300 mg/kg/day with CH, produced a counteractive effect, represented in recompense of biochemical alteration, CD4 and CD8 expression. RJ intake also amended the histological picture. The immunohistochemical picture revealed a decrease in CD3, CD86 and eNOS in the aortic tissue. These findings attributed to the significant immunomodulatory effect of RJ remedy suppress deleterious effects of hypercholesterolaemia.

  7. Prevalence of endothelial nitric oxide synthase (eNOS) gene exon 7 Glu298Asp variant in North Eastern India

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    Shankarishan, Priyanka; Borah, Prasanta Kumar; Ahmed, Giasuddin; Mahanta, Jagadish

    2011-01-01

    Background & objectives Endothelial nitric oxide is a potent vasodilator and impairment of its generation brought about by gene polymorphism is considered a major predictor for several diseases. A single nucleotide polymorphism G894T within exon 7 of endothelial nitric oxide synthase (eNOS-7) gene, resulting in a replacement of glutamic acid by aspartic acid, has been studied as a putative candidate gene for cardiovascular diseases. The pattern of eNOS-7 Glu298Asp variant in the Indian population is poorly known. The present study was planned to determine the prevalence of the variant of this gene among tea garden community in Assam, North-East India with high prevalence of hypertension. Methods Study participants of both sex aged ≥18 yr were recruited randomly from temporary field clinics established in tea gardens of Dibrugarh, Assam. Genomic DNA was extracted from 409 subjects by the conventional phenol-chloroform method. The prevalence of the eNOS exon 7 Glu298Asp variant was determined by polymerase chain reaction and restriction fragment length polymorphism analysis. Results The study population was in Hardy-Weinberg Equilibrium. The frequency of the eNOS GG, GT and TT genotypes was found to be 75, 22 and 3 per cent respectively and did not show any significant difference in gender wise analysis. Interpretation & conclusions Our results showed that the prevalence of the homozygous GG genotype was high (75%) and the rare mutant genotype (homozygous, TT) was 3 per cent in a population at risk with cardiovascular disease. Such population-based data on various polymorphisms can ultimately be exploited in pharmacogenomics. PMID:21623032

  8. Substance P ameliorates tumor necrosis factor-alpha-induced endothelial cell dysfunction by regulating eNOS expression in vitro.

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    Piao, Jiyuan; Hong, Hyun Sook; Son, Youngsook

    2018-04-01

    The aim of this study was to explore the beneficial effects of SP on NO production and inflammation-induced vascular endothelium cell death. To mimic the inflammatory environment, TNF-α was treated with HUVECs, and SP was added prior to TNF-α to determine its protective effect. WST-1 assay was performed to detect cell viability. NO level in conditioned medium was measured by Griess Reagent System. The protein level of cleaved caspase-3, eNOS, and phosphorylated Akt was detected by Western blot analysis. TNF-α declined endothelial cell viability by downregulating Akt and NO production. TNF-α-induced cell death was reliably restored by NO, confirming the requirement of NO for cell survival. By contrast, pretreatment of SP attenuated TNF-α-induced cellular apoptosis, accompanied by an increase in the phosphorylation of Akt, eNOS expression, and NO production. Blockage of NK-1R, phosphorylated Akt or eNOS by CP-96345, A6730, or L-NAME entirely eliminated the effect of SP. SP can protect the vascular endothelium against inflammation-induced damage through modulation of the Akt/eNOS/NO signaling pathway. © 2018 John Wiley & Sons Ltd.

  9. Efectos ecológicos del fenómeno ENOS en Colombia

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    Yesid Carvajal

    2014-06-01

    Full Text Available El fenómeno ENOS, tiene un sustancial efecto sobre las variaciones del clima a nivel mundial; por lo tanto, no sorprende que sus efectos tengan un impacto ecológico y socioeconómico fuerte, alterando la seguridad alimentaria de los países a nivel mundial. Ante este panorama, es comprensible que haya despertado el mayor interés mundial, no sólo en los especialistas en meteorología y oceanografía sino también entre biólogos, ecólogos, físicos, matemáticos, agrónomos, hidrólogos, economistas, sociólogos y planificadores, entre otros. En el presente documento, se muestra algunos de los principales efectos ecológicos en Colombia durante las fases extremas cálida (El Niño y fría (La Niña, indicando que es una necesidad urgente, orientar la investigación en sus causas, consecuencias e impactos.

  10. Association of eNOS and ACE gene polymorphisms and plasma nitric oxide with risk of non-small cell lung cancer in South India.

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    Peddireddy, Vidyullatha; Badabagni, Siva Prasad; Gundimeda, Sandhya Devi; Mundluru, Hema Prasad

    2018-01-01

    The role of ACE and eNOS gene polymorphisms and their association with various cancers were reported. However, their role in the lung cancer is unclear. In this study, we analyzed eNOS and ACE gene polymorphisms and the risk of non-small cell lung cancer (NSCLC) in South Indian population. For the eNOS gene, the homozygous "AA" genotypic frequency was significantly associated with NSCLC with an overall risk of 3.6-fold (P = 0.006, odds ratio = 3.58, 95% confidence interval = 1.66, 7.723). The heterozygous "I/D" genotypic frequency of ACE gene was significantly higher in NSCLC patients when compared to the controls with a 2.29-fold risk for NSCLC. Multiple regression analyses indicated that gender, smoking status, and polymorphisms in eNOS and ACE genes as the strongest predicting factors for an increased susceptibility to NSCLC. We report for the first time that polymorphisms in the eNOS "A/A" (homozygous mutant) and ACE "I/D" genotypes might contribute to the increased risk of NSCLC in the South Indian population. © 2016 John Wiley & Sons Ltd.

  11. Investigation of gene expression and serum levels of PIN1 and eNOS with high blood pressure in patients with Alzheimer disease.

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    Azimi, Mina; Nikanfar, Masoud; Khakikhatibi, Fatemeh; Rahbarghazi, Reza; Nourazarian, Seyed Manuchehr; Biray Avci, Cigir; Nourazarian, Alireza

    2017-09-01

    According to evidence, Alzheimer's disease is known as one of the most serious neurodegenerative diseases, for which hypertension has been observed to be a key risk factor. Therefore, this study aims to examine the relationship between the PIN1 and eNOS genes expression, as well as serum levels and hypertension in Alzheimer's disease sufferers. Blood samples were obtained from subjects who were divided into four groups: the control group, normotensive Alzheimer's patients, the Alzheimer's sufferers group with hypertension, and the healthy group with only hypertension, considering the inhibition of confounding factors. Thereafter, eNOS and PIN1 genes expression along with serum levels were studied. Based on the obtained results, a statistically significant correlation didn't exist between serum level of PIN1 and the systolic and diastolic blood pressure, between serum level of eNOS and diastolic blood pressure in the norm tension Alzheimer's disease patients, between serum levels of PIN1, eNOS and systolic blood pressure, and between serum eNOS and systolic and diastolic blood pressure in the patients with hypertension (pdiseases in Alzheimer's disease. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Effects of atorvastatin and T-786C polymorphism of eNOS gene on plasma metabolic lipid parameters.

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    Zago, Vanessa Helena de Souza; Santos, José Eduardo Tanus dos; Danelon, Mirian Regina Gardin; Silva, Roger Marcelo Mesquita da; Panzoldo, Natália Baratella; Parra, Eliane Soler; Alexandre, Fernanda; Virgínio, Vítor Wilson de Moura; Quintão, Eder Carlos Rocha; Faria, Eliana Cotta de

    2013-01-01

    Endothelial nitric oxide synthase (eNOS) activity may be modulated by high-density lipoprotein cholesterol (HDL-C), statins or polymorphisms, such as the T-786C of eNOS. This study aimed at evaluating if the T-786C polymorphism is associated with changes of atorvastatin effects on the lipid profile, on the concentrations of metabolites of nitric oxide (NO) and of high sensitivity C-reactive protein (hsCRP). Thirty male volunteers, asymptomatic, aged between 18 and 56 years were genotyped and classified according to absence (TT, n = 15) or presence (CC, n = 15) of the polymorphism. They were randomly selected for the use of placebo or atorvastatin (10 mg/day/14 days). After each treatment lipids, lipoproteins, HDL2 and HDL3 composition, cholesteryl ester transfer protein (CETP) activity, metabolites of NO and hsCRP were evaluated. The comparisons between genotypes after placebo showed an increase in CETP activity in a polymorphism-dependent way (TT, 12±7; CC, 22±12; p < 0.05). The interaction analyses between treatments indicated that atorvastatin has an effect on cholesterol, LDL, nitrite and lipid-protein ratios (HDL2 and HDL3) (p < 0.001) in both genotypes. Interestingly, we observed genotype/drug interactions on CETP (p < 0.07) and lipoprotein (a) (Lp(a)) (p < 0.056), leading to a borderline decrease in CETP, but with no effect on Lp(a). HsCRP showed no alteration. These results suggest that statin treatment may be relevant for primary prevention of atherosclerosis in patients with the T-786C polymorphism of eNOS, considering the effects on lipid metabolism.

  13. eNOS se correlaciona com a biogênese mitocondrial em corações com cardiopatia congênita e cianose eNOS correlates with mitochondrial biogenesis in hearts of congenital heart disease with cyanosis

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    Juan Xiao

    2012-09-01

    Full Text Available FUNDAMENTO: O programa de biogênese mitocondrial no coração parece apresentar remodelação adaptativa após estresse biomecânico e oxidativo. Os mecanismos adaptativos que protegem o metabolismo do miocárdio durante a hipóxia são coordenados, em parte, pelo óxido nítrico (NO. OBJETIVO: Observar a biogênese mitocondrial e expressão do óxido nítrico sintase (NOS em corações de cardiopatia congênita com cianose; discutir a resposta mitocondrial à hipóxia crônica do miocárdio. MÉTODOS: Foram investigados 20 pacientes com defeitos cardíacos cianóticos (n = 10 ou acianóticos (n = 10. Foram estudadas amostras do miocárdio na via de saída ventricular direita, tomadas durante a operação. A análise morfométrica de mitocôndrias foi realizada por microscopia eletrônica de transmissão. A relação mtDNA/nDNA foi determinada com PCR em tempo real. Os níveis de transcrição da subunidade I da citocromo c oxidase (COXI, coativador-1α do receptor γ ativado por proliferador de peroxissoma (PGC-1α, o fator respiratório nuclear 1 (NRF1, e fator de transcrição mitocondrial A (Tfam foram detectados por reação em cadeia da polimerase via transcriptase reversa (RT-PCR ativado por fluorescência em tempo real. Os níveis proteicos de COXI e nNOS, iNOS e eNOS foram medidos por técnica de Western Blot. RESULTADOS: A densidade volumétrica mitocondrial (Vv e a densidade numérica (Nv foram significativamente elevadas em pacientes com cianose, em comparação com a cardiopatia congênita acianótica. MtDNA elevada e suprarregulação dos níveis de COXI, PGC-1 α, NRF1 e Tfam mRNA foram observadas em pacientes cianóticos. Os níveis de proteína de COXI e eNOS foram significativamente maiores no miocárdio de pacientes cianóticos que nos de acianóticos. Os níveis de transcrição do PGC-1α se correlacionam com os níveis de eNOS. CONCLUSÃO: A biogênese mitocondrial é ativada no miocárdio da via de saída ventricular na

  14. Relationship between endothelial nitric oxide synthase (eNOS) and natural history of intracranial aneurysms: meta-analysis.

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    Paschoal, Eric Homero Albuquerque; Yamaki, Vitor Nagai; Teixeira, Renan Kleber Costa; Paschoal Junior, Fernando Mendes; Jong-A-Liem, Glaucia Suzanna; Teixeira, Manoel Jacobsen; Yamada, Elizabeth Sumi; Ribeiro-Dos-Santos, Ândrea; Bor-Seng-Shu, Edson

    2018-01-01

    The aneurysmal subarachnoid hemorrhage is a major public health problem described as a sudden drastic event with no warning symptoms and high morbidity and mortality rates. The role of the endothelial isoform of nitric oxide synthase gene polymorphism in intracranial aneurysms (IAs) is still a matter of controversy with divergent findings among European, American, and Asian populations. Our study purposed to test the association between intracranial aneurysms formation and nitric oxide gene polymorphisms through a systematic review and meta-analysis. Systematic search on Medline, Lilacs, and EMBASE was performed. The primary search resulted in 139 papers, out of which 9 met our inclusion criteria after a full text analysis. The dominant T786C model found a significant association with IA (OR 1.22, 95 % CI 1.04-1.44, p = 0.01), so did studies of the recessive T786C model (OR 0.37, 95 % CI 0.30-0.45, p < 0.0001) but with opposite effect. Our findings support the presence of the T786C polymorphism as a predictor for the development of intracranial aneurysm in the cerebral vascular system. More studies are necessary in order to elucidate the pathways of the endothelial nitric oxide synthase (eNOS) in cerebrovascular diseases and in defining how different allelic combinations of the eNOS gene single-nucleotide polymorphism (SNP) could favor this pathological process.

  15. Prunella vulgaris Suppresses HG-Induced Vascular Inflammation via Nrf2/HO-1/eNOS Activation

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    Ho Sub Lee

    2012-01-01

    Full Text Available Vascular inflammation is an important factor which can promote diabetic complications. In this study, the inhibitory effects of aqueous extract from Prunella vulgaris (APV on high glucose (HG-induced expression of cell adhesion molecules in human umbilical vein endothelial cells (HUVEC are reported. APV decreased HG-induced expression of intercellular adhesion molecule-1 (ICAM-1, vascular cell adhesion molecule-1 (VCAM-1, and E-selectin. APV also dose-dependently inhibited HG-induced adhesion of HL-60 monocytic cells. APV suppressed p65 NF-κB activation in HG-treated cells. APV significantly inhibited the formation of intracellular reactive oxygen species (ROS. HG-stimulated HUVEC secreted gelatinases, however, APV inhibited it. APV induced Akt phosphorylation as well as activation of heme oxygenase-1 (HO-1, eNOS, and nuclear factor E2-related factor 2 (Nrf2, which may protect vascular inflammation caused by HG. In conclusion, APV exerts anti-inflammatory effect via inhibition of ROS/NF-κB pathway by inducing HO-1 and eNOS expression mediated by Nrf2, thereby suggesting that Prunella vulgaris may be a possible therapeutic approach to the inhibition of diabetic vascular diseases.

  16. Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS

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    Mohamed A. Morsy

    2014-01-01

    Full Text Available Gentamicin, an aminoglycoside antibiotic, is used for the treatment of serious Gram-negative infections. However, its usefulness is limited by its nephrotoxicity. Sildenafil, a selective phosphodiesterase-5 inhibitor, was reported to prevent or decrease tissue injury. The aim of this study is to evaluate the potential protective effects of sildenafil on gentamicin-induced nephrotoxicity in rats. Male Wistar rats were injected with gentamicin (100 mg/kg/day, i.p. for 6 days with and without sildenafil. Sildenafil administration resulted in nephroprotective effect in gentamicin-intoxicated rats as it significantly decreased serum creatinine and urea, urinary albumin, and renal malondialdehyde and nitrite/nitrate levels, with a concomitant increase in renal catalase and superoxide dismutase activities compared to gentamicin-treated rats. Moreover, immunohistochemical examination revealed that sildenafil treatment markedly reduced inducible nitric oxide synthase (iNOS expression, while expression of endothelial nitric oxide synthase (eNOS was markedly enhanced. The protective effects of sildenafil were verified histopathologically. In conclusion, sildenafil protects rats against gentamicin-induced nephrotoxicity possibly, in part, through its antioxidant activity, inhibition of iNOS expression, and induction of eNOS production.

  17. NOX4-dependent Hydrogen peroxide promotes shear stress-induced SHP2 sulfenylation and eNOS activation.

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    Sánchez-Gómez, Francisco J; Calvo, Enrique; Bretón-Romero, Rosa; Fierro-Fernández, Marta; Anilkumar, Narayana; Shah, Ajay M; Schröder, Katrin; Brandes, Ralf P; Vázquez, Jesús; Lamas, Santiago

    2015-12-01

    Laminar shear stress (LSS) triggers signals that ultimately result in atheroprotection and vasodilatation. Early responses are related to the activation of specific signaling cascades. We investigated the participation of redox-mediated modifications and in particular the role of hydrogen peroxide (H2O2) in the sulfenylation of redox-sensitive phosphatases. Exposure of vascular endothelial cells to short periods of LSS (12 dyn/cm(2)) resulted in the generation of superoxide radical anion as detected by the formation of 2-hydroxyethidium by HPLC and its subsequent conversion to H2O2, which was corroborated by the increase in the fluorescence of the specific peroxide sensor HyPer. By using biotinylated dimedone we detected increased total protein sulfenylation in the bovine proteome, which was dependent on NADPH oxidase 4 (NOX4)-mediated generation of peroxide. Mass spectrometry analysis allowed us to identify the phosphatase SHP2 as a protein susceptible to sulfenylation under LSS. Given the dependence of FAK activity on SHP2 function, we explored the role of FAK under LSS conditions. FAK activation and subsequent endothelial NO synthase (eNOS) phosphorylation were promoted by LSS and both processes were dependent on NOX4, as demonstrated in lung endothelial cells isolated from NOX4-null mice. These results support the idea that LSS elicits redox-sensitive signal transduction responses involving NOX4-dependent generation of hydrogen peroxide, SHP2 sulfenylation, and ulterior FAK-mediated eNOS activation. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Enolase 1 (ENO1 and protein disulfide-isomerase associated 3 (PDIA3 regulate Wnt/β-catenin-driven trans-differentiation of murine alveolar epithelial cells

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    Kathrin Mutze

    2015-08-01

    Full Text Available The alveolar epithelium represents a major site of tissue destruction during lung injury. It consists of alveolar epithelial type I (ATI and type II (ATII cells. ATII cells are capable of self-renewal and exert progenitor function for ATI cells upon alveolar epithelial injury. Cell differentiation pathways enabling this plasticity and allowing for proper repair, however, are poorly understood. Here, we applied proteomics, expression analysis and functional studies in primary murine ATII cells to identify proteins and molecular mechanisms involved in alveolar epithelial plasticity. Mass spectrometry of cultured ATII cells revealed a reduction of carbonyl reductase 2 (CBR2 and an increase in enolase 1 (ENO1 and protein disulfide-isomerase associated 3 (PDIA3 protein expression during ATII-to-ATI cell trans-differentiation. This was accompanied by increased Wnt/β-catenin signaling, as analyzed by qRT-PCR and immunoblotting. Notably, ENO1 and PDIA3, along with T1α (podoplanin; an ATI cell marker, exhibited decreased protein expression upon pharmacological and molecular Wnt/β-catenin inhibition in cultured ATII cells, whereas CBR2 levels were stabilized. Moreover, we analyzed primary ATII cells from mice with bleomycin-induced lung injury, a model exhibiting activated Wnt/β-catenin signaling in vivo. We observed reduced CBR2 significantly correlating with surfactant protein C (SFTPC, whereas ENO1 and PDIA3 along with T1α were increased in injured ATII cells. Finally, siRNA-mediated knockdown of ENO1, as well as PDIA3, in primary ATII cells led to reduced T1α expression, indicating diminished cell trans-differentiation. Our data thus identified proteins involved in ATII-to-ATI cell trans-differentiation and suggest a Wnt/β-catenin-driven functional role of ENO1 and PDIA3 in alveolar epithelial cell plasticity in lung injury and repair.

  19. Alteration in cardiac uncoupling proteins and eNOS gene expression following high-intensity interval training in favor of increasing mechanical efficiency.

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    Fallahi, Ali Asghar; Shekarfroush, Shahnaz; Rahimi, Mostafa; Jalali, Amirhossain; Khoshbaten, Ali

    2016-03-01

    High-intensity interval training (HIIT) increases energy expenditure and mechanical energy efficiency. Although both uncoupling proteins (UCPs) and endothelial nitric oxide synthase (eNOS) affect the mechanical efficiency and antioxidant capacity, their effects are inverse. The aim of this study was to determine whether the alterations of cardiac UCP2, UCP3, and eNOS mRNA expression following HIIT are in favor of increased mechanical efficiency or decreased oxidative stress. Wistar rats were divided into five groups: control group (n=12), HIIT for an acute bout (AT1), short term HIIT for 3 and 5 sessions (ST3 and ST5), long-term training for 8 weeks (LT) (6 in each group). The rats of the training groups were made to run on a treadmill for 60 min in three stages: 6 min running for warm-up, 7 intervals of 7 min running on treadmill with a slope of 5° to 20° (4 min with an intensity of 80-110% VO2max and 3 min at 50-60% VO2max), and 5-min running for cool-down. The control group did not participate in any exercise program. Rats were sacrificed and the hearts were extracted to analyze the levels of UCP2, UCP3 and eNOS mRNA by RT-PCR. UCP3 expression was increased significantly following an acute training bout. Repeated HIIT for 8 weeks resulted in a significant decrease in UCPs mRNA and a significant increase in eNOS expression in cardiac muscle. This study indicates that Long term HIIT through decreasing UCPs mRNA and increasing eNOS mRNA expression may enhance energy efficiency and physical performance.

  20. Eno-culture and Identity: The installation as a new methodology in Artistic Research and Heritage Education

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    Ruth Marañón Martínez de la Puente

    2018-03-01

    Full Text Available The aesthetic experience and the artistic knowledge always have been connected with the Heritage Education, due to the great importance in rewarding pedagogic processes, specially, in non-formal spaces. In our research, the installation (with its features and competences has turned into the most interesting educational tool to transform the reality of our work’s context: Rioja Alavesa. Thus, across the workshops "Instálate" (organized inside different wineries of the region, we worked the Wine Cultural Heritage (Eno-culture, the Artistic Research and the knowledge based on the sensitive experience. In this article, we showed the results of this experience, proposing the installation as a new interesting and practical method of Artistic Research in Heritage Education. In conclusion, we propose the art-installation as a different key to work the identity, contemporary art, culture and heritage.

  1. Chronic aerobic exercise associated to dietary modification improve endothelial function and eNOS expression in high fat fed hamsters.

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    Beatriz C S Boa

    Full Text Available Obesity is epidemic in the western world and central adipose tissue deposition points to increased cardiovascular morbidity and mortality, independently of any association between obesity and other cardiovascular risk factors. Physical exercise has been used as non-pharmacological treatment to significantly reverse/attenuate obesity comorbidities. In this study we have investigated effects of exercise and/or dietary modification on microcirculatory function, body composition, serum glucose, iNOS and eNOS expression on 120 male hamsters treated for 12 weeks with high fat chow (HF, n = 30 starting on the 21st day of birth. From week 12 to 20, animals were randomly separated in HF (no treatment change, return to standard chow (HFSC, n = 30, high fat chow associated to an aerobic exercise training program (AET (HFEX, n = 30 and return to standard chow+AET (HFSCEX, n = 30. Microvascular reactivity in response to acetylcholine and sodium nitroprusside and macromolecular permeability increase induced by 30 minutes ischemia followed by reperfusion were assessed on the cheek pouch preparation. Total body fat and aorta eNOS and iNOS expression by immunoblotting assay were evaluated on the experimental day. Compared to HFSC and HFSCEX groups, HF and HFEX ones presented increased visceral fat [(mean±SEM (HF4.9±1.5 g and (HFEX4.7±0.9 g vs. (HFSC*3.0±0.7 g and (HFSCEX*1.9±0.4 g/100 g BW]; impaired endothelial-dependent vasodilatation [Ach 10(-8 M (HF87.9±2.7%; (HFSC*116.7±5.9%; (HFEX*109.1±4.6%; (HFSCEX*105±2.8%; Ach10(-6 M (HF95.3±3.1%; (HFSC*126±6.2%; (HFEX*122.5±2.8%; (HFSCEX*118.1±4.3% and Ach10(-4 M (HF109.5±4.8%; (HFSC*149.6±6.6%; (HFEX*143.5±5.4% and (HFSCEX*139.4±5.2%], macromolecular permeability increase after ischemia/reperfusion [(HF40.5±4.2; (HFSC*19.0±1.6; (HFEX*18.6±2.1 and (HFSCEX* 21.5±3.7 leaks/cm2, decreased eNOS expression, increased leptin and glycaemic levels. Endothelial-independent microvascular

  2. A Multilevel Prediction of Physiological Response to Challenge: Interactions among Child Maltreatment, Neighborhood Crime, eNOS and GABRA6

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    Lynch, Michael; Manly, Jody Todd; Cicchetti, Dante

    2015-01-01

    Physiological response to stress has been linked to variety of healthy and pathological conditions. The current study conducted a multilevel examination of interactions among environmental toxins – i.e., neighborhood crime and child maltreatment – and specific genetic polymorphisms of eNOS and GABRA6. A total of 186 children were recruited at age 4. At this time, the presence or absence of child maltreatment was determined, as was the amount of crime that occurred in their neighborhood during the previous year. At age 9, the children were brought to the lab where their physiological response to a cognitive challenge – i.e., change in the amplitude of RSA – was assessed and DNA samples were collected for subsequent genotyping. Results confirmed that complex G x G, E x E, and G x E interactions were associated with different patterns of RSA reactivity. The implications for future research and evidence-based intervention are discussed. PMID:26535938

  3. Effects of aerobic exercise on the blood pressure, oxidative stress and eNOS gene polymorphism in pre-hypertensive older people.

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    Zago, Anderson Saranz; Park, Joon-Young; Fenty-Stewart, Nicola; Silveira, Leonardo Reis; Kokubun, Eduardo; Brown, Michael D

    2010-11-01

    The polymorphisms of endothelial nitric oxide synthase (eNOS) are associated with reduced eNOS activity. Aerobic exercise training (AEX) may influence resting nitric oxide (NO) production, oxidative stress and blood pressure. The purpose of this study was to investigate the effect of AEX on the relationship among blood pressure, eNOS gene polymorphism and oxidative stress in pre-hypertensive older people. 118 pre-hypertensive subjects (59 ± 6 years) had blood samples collected after a 12 h overnight fast for assessing plasma NO metabolites (NOx) assays, thiobarbituric acid reactive substances (T-BARS) and superoxide dismutase activity (ecSOD). eNOS polymorphism (T-786C and G-894T) was done by standard PCR methods. All people were divided according to the genotype results (G1: TT/GG, G2: TT/GT + TT, G3: TC + CC/GG, G4: TC + CC/GT + TT). All parameters were measured before and after 6 months of AEX (70% of VO(2 max)). At baseline, no difference was found in systolic and diastolic blood pressure, ecSOD and T-BARS activity. Plasma NOx levels were significantly different between G1 (19 ± 1 μM) and G4 (14.2 ± 0.6 μM) and between G2 (20.1 ± 1.7 μM) and G4 (14.2 ± 0.6 μM). Therefore, reduced NOx concentration in G4 group occurred only when the polymorphisms were associated, suggesting that these results are more related to genetic factors than NO-scavenging effect. After AEX, the G4 increased NOx values (17.2 ± 1.2 μM) and decreased blood pressure. G1, G3 and G4 decreased T-BARS levels. These results suggest the AEX can modulate the NOx concentration, eNOS activity and the relationship among eNOS gene polymorphism, oxidative stress and blood pressure especially in C (T-786C) and T (G-894T) allele carriers.

  4. Evaluation of Protective Immune Responses Induced by Recombinant TrxLp and ENO2 Proteins against Toxoplasma gondii Infection in BALB/c Mice

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    Meng Wang

    2016-01-01

    Full Text Available Toxoplasma gondii is an obligate intracellular parasitic protozoan that can infect almost all species of warm-blooded animals. As any chemical-based drugs could not act against the tissue cyst stage of T. gondii, vaccination may be one of the ideal control strategies. In the present study, two new vaccine candidates, named TgENO2 and TgTrxLp, were purified from Escherichia coli with pET-30a(+ expression system and then were injected into BALB/c mice to evaluate the protective efficacy against acute and chronic toxoplasmosis. The results showed that both the recombinant proteins, either alone or in combination, could elicit strong humoral and cellular immune responses with a higher level of IgG antibodies, IFN-γ, IL-2, CD4+, and CD8+ T cells as compared to those in mice from control groups. After acute challenge with tachyzoites of the GJS strain, mice immunized with rTgTrxLp (8±2.77 d, rTgENO2 (7.4±1.81 d, and rTgTrxLp + rTgENO2 (8.38±4.57 d proteins showed significantly longer survival time than those that received Freund’s adjuvant (6.78±2.08 d and PBS (6.38±4.65 d (χ2 = 9.687, df = 4, P=0.046. The protective immunity of rTgTrxLp, rTgENO2, and rTgTrxLp + rTgENO2 proteins against chronic T. gondii infection showed 69.77%, 58.14%, and 20.93% brain cyst reduction as compared to mice that received PBS. The present study suggested that both TgENO2 and TgTrxLp were potential candidates for the development of multicomponent vaccines against toxoplasmosis.

  5. Activation of eNOS by D-pinitol Induces an Endothelium-Dependent Vasodilatation in Mouse Mesenteric Artery

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    Luciana N. Moreira

    2018-05-01

    Full Text Available D-pinitol is a cyclitol present in several edible plant species and extensively investigated for the treatment of metabolic diseases in humans, as food supplement, and demonstrated protective effects in the cardiovascular system. For these reasons, the present work aimed at investigating the mechanisms involved in the vascular effects of D-pinitol in mouse mesenteric artery. Mesenteric arteries from male C57BL/6 mice were mounted in a wire myograph. Nitrite was measured by the 2,3-diaminonaphthalene (DAN method. Protein expression and phosphorylation were measured by Western blot. The systolic blood pressure (SBP was measured by tail-cuff plethysmography. D-pinitol induced a concentration-dependent vasodilatation in endothelium-intact, but not in endothelium-denuded arteries. Nω-Nitro-L-arginine methyl ester (300 μM abolished the effect of D-pinitol, while 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ; 10 μM shifted the concentration-response curve to the right. KN-93 (1 μM blunted the vasodilator effect of D-pinitol, but H-89 (0.1 μM did not change it. 1-[2-(Trifluoromethyl phenyl]imidazole (300 μM, indomethacin (10 μM, celecoxib (5 μM, wortmannin (1 μM, ruthenium red (10 μM, tiron (10 μM, MnTMPyP (30 μM, MPP (0.1 μM, PHTPP (0.1 μM, and atropine (1 μM did not change the effect of D-pinitol. D-pinitol increased the concentration of nitrite, which was inhibited by L-NAME and calmidazolium (10 μM. D-pinitol increased the phosphorylation level of eNOS activation site at Ser1177 and reduced the phosphorylation level of its inactivation site at Thr495. In normotensive mice, the intraperitoneal administration of D-pinitol (10 mg/kg induced a significant reduction of the SBP after 30 min. The present results led us to conclude that D-pinitol has an endothelium- and NO-dependent vasodilator effect in mouse mesenteric artery through a mechanism dependent on the activation of eNOS by the calcium-calmodulin complex, which can explain its

  6. Variable effects of maternal and paternal-fetal contribution to the risk for preeclampsia combining GSTP1, eNOS, and LPL gene polymorphisms.

    Science.gov (United States)

    Pappa, Kalliopi I; Roubelakis, Maria; Vlachos, George; Marinopoulos, Spyros; Zissou, Antonia; Anagnou, Nicholas P; Antsaklis, Aris

    2011-04-01

    To evaluate the maternal, paternal, and fetal genotype contribution to preeclampsia. STUDY DESIGN, MATERIALS, AND METHODS: We combined the analysis of polymorphisms of the GSTP1, eNOS, and LPL genes - affecting biotransformation enzymes and endothelial function - in a cohort of 167 preeclamptic and normal control trios (mother, father, and child) comprising a total of 501 samples in the Greek population, never analyzed before by this approach. For the frequency of the GSTP1 Ile(105)/Val(105), the eNOS Glu298Asp and the LPL-93 polymorphisms, statistically significant differences were found between the two groups. However, the transmission rates of the parental alleles to neonates studied by the transmission disequilibrium test, disclosed no increased rate of transmission to preeclampsia children for the variant alleles of Val(105) GSTP1, 298Asp eNOS, and -93G LPL. These novel data, suggest that interaction of all three types of genotypes (mother, father and neonate), reveals no effects on the development of preeclampsia, but provide the impetus for further studies to decipher the individual contribution of each genetic parameter of preeclampsia.

  7. Exercise Training Could Improve Age-Related Changes in Cerebral Blood Flow and Capillary Vascularity through the Upregulation of VEGF and eNOS

    Directory of Open Access Journals (Sweden)

    Sheepsumon Viboolvorakul

    2014-01-01

    Full Text Available This study aimed to investigate the effect of exercise training on age-induced microvascular alterations in the brain. Additionally, the association with the protein levels of vascular endothelial growth factor (VEGF and endothelial nitric oxide synthase (eNOS was also assessed. Male Wistar rats were divided into four groups: sedentary-young (SE-Young, n=5, sedentary aged (SE-Aged, n=8, immersed-aged (IM-Aged, n=5, and exercise trained-aged (ET-Aged, 60 minutes/day and 5 days/week for 8 weeks, n=8 rats. The MAPs of all aged groups, SE-Aged, IM-Aged, and ET-Aged, were significantly higher than that of the SE-Young group. The regional cerebral blood flow (rCBF in the SE-Aged and IM-Aged was significantly decreased as compared to SE-Young groups. However, rCBF of ET-Aged group was significantly higher than that in the IM-Aged group (P<0.05. Moreover, the percentage of capillary vascularity (%CV and the levels of VEGF and eNOS in the ET-Aged group were significantly increased compared to the IM-Aged group (P<0.05. These results imply that exercise training could improve age-induced microvascular changes and hypoperfusion closely associated with the upregulation of VEGF and eNOS.

  8. Marine Compound Catunaregin Inhibits Angiogenesis through the Modulation of Phosphorylation of Akt and eNOS in vivo and in vitro

    Directory of Open Access Journals (Sweden)

    Jun-Xiu Liu

    2014-05-01

    Full Text Available Angiogenesis is the formation of blood vessels from pre-existing vasculature. Excessive or uncontrolled angiogenesis is a major contributor to many pathological conditions whereas inhibition of aberrant angiogenesis is beneficial to patients with pathological angiogenesis. Catunaregin is a core of novel marine compound isolated from mangrove associate. The potential anti-angiogenesis of catunaregin was investigated in human umbilical vein endothelial cells (HUVECs and zebrafish. HUVECs were treated with different concentrations of catunaregin in the presence or absence of VEGF. The angiogenic phenotypes including cell invasion cell migration and tube formation were evaluated following catunaregin treatment in HUVECs. The possible involvement of AKT, eNOS and ERK1/2 in catunaregin-induced anti-angiogenesis was explored using Western blotting. The anti-angiogenesis of catunaregin was further tested in the zebrafish embryo neovascularization and caudal fin regeneration assays. We found that catunaregin dose-dependently inhibited angiogenesis in both HUVECs and zebrafish embryo neovascularization and zebrafish caudal fin regeneration assays. In addition, catunaregin significantly decreased the phosphorylation of Akt and eNOS, but not the phosphorylation of ERK1/2. The present work demonstrates that catunaregin exerts the anti-angiogenic activity at least in part through the regulation of the Akt and eNOS signaling pathways.

  9. Expression profiles of eNOS, iNOS and microRNA-27b in the corpus cavernosum of rats submitted to chronic alcoholism and Diabetes mellitus.

    Science.gov (United States)

    Cunha, Joao Paulo da; Lizarte, Fermino Sanches; Novais, Paulo Cezar; Gattas, Daniela; Carvalho, Camila Albuquerque Mello de; Tirapelli, Daniela Pretti da Cunha; Molina, Carlos Augusto Fernandes; Tirapelli, Luis Fernando; Tucci, Silvio

    2017-01-01

    To evaluate the expression of endothelial and inducible NOS in addition to the miRNA-27b in the corpus cavernosum and peripheral blood of healthy rats, diabetic rats, alcoholic rats and rats with both pathologies. Forty eight Wistar rats were divided into four groups: control (C), alcoholic (A), diabetic (D) and alcoholic-diabetic (AD). Samples of the corpus cavernosum were prepared to study protein expressions of eNOS and iNOS by immunohistochemistry and expression of miRNA-27b in the corpus cavernosum and peripheral blood. Immunohistochemistry for eNOS and iNOS showed an increase in cavernosal smooth muscle cells in the alcoholic, diabetic and alcoholic-diabetic groups when compared with the control group. Similarly, the mRNA levels for eNOS were increased in cavernosal smooth muscle (CSM) in the alcoholic, diabetic and alcoholic-diabetic groups and miRNA-27b were decreased in CSM in the alcoholic, diabetic and alcoholic-diabetic groups. The major new finding of our study was an impairment of relaxation of cavernosal smooth muscle in alcoholic, diabetic, and alcoholic-diabetic rats that involved a decrease in the nitric oxide pathway by endothelium-dependent mechanisms accompanied by a change in the corpus cavernosum contractile sensitivity.

  10. Glycolipids from spinach suppress LPS-induced vascular inflammation through eNOS and NK-κB signaling.

    Science.gov (United States)

    Ishii, Masakazu; Nakahara, Tatsuo; Araho, Daisuke; Murakami, Juri; Nishimura, Masahiro

    2017-07-01

    Glycolipids are the major constituent of the thylakoid membrane of higher plants and have a variety of biological and pharmacological activities. However, anti-inflammatory effects of glycolipids on vascular endothelial cells have not been elucidated. Here, we investigated the effect of glycolipids extracted from spinach on lipopolysaccharides (LPS)-induced endothelial inflammation and evaluated the underlying molecular mechanisms. Treatment with glycolipids from spinach had no cytotoxic effects on cultured human umbilical vein endothelial cells (HUVECs) and significantly blocked the expression of LPS-induced interleukin (IL)-6, monocyte chemoattractant protein-1 (MCP-1), vascular cell adhesion molecule-1 (VCAM-1), and intracellular adhesion molecule-1 (ICAM-1) in them. Glycolipids treatment also effectively suppressed monocyte adhesion to HUVECs. Treatment with glycolipids inhibited LPS-induced NF-κB phosphorylation and nuclear translocation. In addition, glycolipids treatment significantly promoted endothelial nitric oxide synthase (eNOS) activation and nitric oxide (NO) production in HUVECs. Furthermore, glycolipids treatment blocked LPS-induced inducible NOS (iNOS) expression in HUVECs. Pretreatment with a NOS inhibitor attenuated glycolipids-induced suppression of NF-κB activation and adhesion molecule expression, and abolished the glycolipids-mediated suppression of monocyte adhesion to HUVECs. These results indicate that glycolipids suppress LPS-induced vascular inflammation through attenuation of the NF-κB pathway by increasing NO production in endothelial cells. These findings suggest that glycolipids from spinach may have a potential therapeutic use for inflammatory vascular diseases. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  11. The effect of high protein diet and exercise on irisin, eNOS, and iNOS expressions in kidney.

    Science.gov (United States)

    Tastekin, Ebru; Palabiyik, Orkide; Ulucam, Enis; Uzgur, Selda; Karaca, Aziz; Vardar, Selma Arzu; Yilmaz, Ali; Aydogdu, Nurettin

    2016-08-01

    Long-term effects of high protein diets (HPDs) on kidneys are still not sufficiently studied. Irisin which increases oxygen consumption and thermogenesis in white fat cells was shown in skeletal muscles and many tissues. Nitric oxide synthases (NOS) are a family of enzymes catalyzing the production of nitric oxide (NO) from L-arginine. We aimed to investigate the effects of HPD, irisin and NO expression in kidney and relation of them with exercise and among themselves. Animals were grouped as control, exercise, HPD and exercise combined with HPD (exercise-HPD). Rats were kept on a HPD for 5 weeks and an exercise program was given them as 5 exercise and 2 rest days per week exercising on a treadmill with increasing speed and angle. In our study, while HPD group had similar total antioxidant capacity (TAC) levels with control group, exercise and exercise-HPD groups had lower levels (p highly selective and quite clear in this study. Effects of exercise and HPD on kidney should be evaluated with different exercise protocols and contents of the diet. İrisin, eNOS, and iNOS staining localizations should be supported with various research studies.

  12. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Martina; Baker, Meredith B.; Moore, Jeffrey P. [Division of Cardiology, Emory University, 1639 Pierce Drive, WMB 319, Atlanta, GA 30322 (United States); Searles, Charles D., E-mail: csearle@emory.edu [Division of Cardiology, Emory University, 1639 Pierce Drive, WMB 319, Atlanta, GA 30322 (United States); Atlanta Veterans Administration Medical Center, 1670 Clarimont Road, Decatur, GA 30033 (United States)

    2010-03-19

    Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. miRNAs are known to have an important role in modulating EC biology, but their expression and functions in cells subjected to shear stress conditions are unknown. We sought to determine the miRNA expression profile in human ECs subjected to unidirectional shear stress and define the role of miR-21 in shear stress-induced changes in EC function. TLDA array and qRT-PCR analysis performed on HUVECs exposed to prolonged unidirectional shear stress (USS, 24 h, 15 dynes/cm{sup 2}) identified 13 miRNAs whose expression was significantly upregulated (p < 0.05). The miRNA with the greatest change was miR-21; it was increased 5.2-fold (p = 0.002) in USS-treated versus control cells. Western analysis demonstrated that PTEN, a known target of miR-21, was downregulated in HUVECs exposed to USS or transfected with pre-miR-21. Importantly, HUVECs overexpressing miR-21 had decreased apoptosis and increased eNOS phosphorylation and nitric oxide (NO{sup {center_dot}}) production. These data demonstrate that shear stress forces regulate the expression of miRNAs in ECs, and that miR-21 influences endothelial biology by decreasing apoptosis and activating the NO{sup {center_dot}} pathway. These studies advance our understanding of the mechanisms by which shear stress forces modulate vascular homeostasis.

  13. Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis.

    Science.gov (United States)

    Kirkby, Nicholas S; Tesfai, Abel; Ahmetaj-Shala, Blerina; Gashaw, Hime H; Sampaio, Walkyria; Etelvino, Gisele; Leão, Nádia Miricéia; Santos, Robson A; Mitchell, Jane A

    2016-12-01

    Nonsteroidal antiinflammatory drugs, including ibuprofen, are among the most commonly used medications and produce their antiinflammatory effects by blocking cyclooxygenase (COX)-2. Their use is associated with increased risk of heart attacks caused by blocking COX-2 in the vasculature and/or kidney, with our recent work implicating the endogenous NOS inhibitor asymmetric dimethylarginine (ADMA), a cardiotoxic hormone whose effects can be prevented by l-arginine. The ibuprofen salt ibuprofen arginate (Spididol) was created to increase solubility but we suggest that it could also augment the NO pathway through codelivery of arginine. Here we investigated the idea that ibuprofen arginate can act to simultaneously inhibit COX-2 and preserve the NO pathway. Ibuprofen arginate functioned similarly to ibuprofen sodium for inhibition of mouse/human COX-2, but only ibuprofen arginate served as a substrate for NOS. Ibuprofen arginate but not ibuprofen sodium also reversed the inhibitory effects of ADMA and N G -nitro-l-arginine methyl ester on inducible NOS (macrophages) and endothelial NOS in vitro (aorta) and in vivo (blood pressure). These observations show that ibuprofen arginate provides, in one preparation, a COX-2 inhibitor and NOS substrate that could act to negate the harmful cardiovascular consequences mediated by blocking renal COX-2 and increased ADMA. While remarkably simple, our findings are potentially game-changing in the nonsteroidal antiinflammatory drug arena.-Kirkby, N. S., Tesfai, A., Ahmetaj-Shala, B., Gashaw, H. H., Sampaio, W., Etelvino, G., Leão, N. M., Santos, R. A., Mitchell, J. A. Ibuprofen arginate retains eNOS substrate activity and reverses endothelial dysfunction: implications for the COX-2/ADMA axis. © The Author(s).

  14. Arginase up-regulation and eNOS uncoupling contribute to impaired endothelium-dependent vasodilation in a rat model of intrauterine growth restriction.

    Science.gov (United States)

    Grandvuillemin, Isabelle; Buffat, Christophe; Boubred, Farid; Lamy, Edouard; Fromonot, Julien; Charpiot, Philippe; Simoncini, Stephanie; Sabatier, Florence; Dignat-George, Françoise; Peyter, Anne-Christine; Simeoni, Umberto; Yzydorczyk, Catherine

    2018-05-09

    Individuals born after intrauterine growth restriction (IUGR) are at increased risk of developing cardiovascular diseases in adulthood, notably hypertension (HTN). Alterations in the vascular system, particularly impaired endothelium-dependent vasodilation, may play an important role in long-term effects of IUGR. Whether such vascular dysfunction precedes HTN has not been fully established in individuals born after IUGR. Moreover, the intimate mechanisms of altered endothelium-dependent vasodilation remain incompletely elucidated. We therefore investigated, using a rat model of IUGR, whether impaired endothelium-dependent relaxation precedes the development of HTN and whether key components of the L-Arginine-nitric oxide (NO) pathway are involved in its pathogenesis. Pregnant rats were fed with a control (CTRL, 23% casein) or low-protein diet (LP, 9% casein) to induce IUGR. Systolic blood pressure (SBP) was measured by tail-cuff plethysmography in 5- and 8-week-old male offspring. Aortic rings were isolated to investigate relaxation to acetylcholine, NO production, eNOS protein content, arginase activity, and superoxide anion production. SBP was not different at 5 weeks, but significantly increased in 8-week-old LP vs. CRTL offspring. In 5-week-old LP vs. CRTL males, endothelium-dependent vasorelaxation was significantly impaired, but restored by pre-incubation with L-Arginine or the arginase inhibitor BEC; NO production was significantly reduced, but restored by L-Arginine pretreatment; total eNOS protein, dimer/monomer ratio, and arginase activity were significantly increased; superoxide anion production was significantly enhanced, but normalized by pretreatment with the NOS inhibitor L-NNA. In this model, IUGR leads to early-impaired endothelium-dependent vasorelaxation, resulting from arginase up-regulation and eNOS uncoupling, which precedes the development of HTN.

  15. Enhanced estradiol-induced vasorelaxation in aortas from type 2 diabetic mice may reflect a compensatory role of p38 MAPK-mediated eNOS activation.

    Science.gov (United States)

    Taguchi, Kumiko; Morishige, Akitaka; Matsumoto, Takayuki; Kamata, Katsuo; Kobayashi, Tsuneo

    2012-08-01

    Cardiovascular problems are a major cause of morbidity and mortality, mainly due to coronary artery disease and atherosclerosis, in type 2 diabetes mellitus. However, female gender is a protective factor in the development of, for example, atherosclerosis and hypertension. One of the female hormones, 17β-estradiol (E2), is known to protect against the cardiovascular injury resulting from endothelial dysfunction, but the mechanism by which it does so remains unknown. Our hypothesis was that E2-mediated activation of Akt and mitogen-activated protein kinase (MAPK), and the subsequent endothelial NO synthase (eNOS) phosphorylation, might protect the aorta in diabetic mellitus. The experimental type 2 diabetic model we employed to test that hypothesis (female mice given streptozotocin and nicotinamide) is here termed fDM. In fDM aortas, we examined the E2-induced relaxation response and the associated protein activities. In control (age-matched, nondiabetic) aortas, E2 induced a vascular relaxation response that was mediated via Akt/eNOS and mitogen-activated/ERK-activating kinase (MEK)/eNOS pathways. In fDM aortas (vs. control aortas), (a) the E2-induced relaxation was enhanced, (b) the mediation of the response was different (via Akt/eNOS and p38 MAPK/eNOS pathways), and (c) E2 stimulation increased p38 MAPK and eNOS phosphorylations, decreased MEK phosphorylation, but did not alter estrogen receptor activity. We infer that at least in fDM aortas, E2 has beneficial effects (enhanced vascular relaxation and protection) that are mediated through Akt activation and (compensating for reduced MEK activation) p38 MAPK activation, leading to enhanced eNOS phosphorylation.

  16. Influence of eNOS gene 4a/bVNTR polymorphism on development of endothelial dysfunction and respiratory system disorders in children - residents of radioactively contaminated areas

    International Nuclear Information System (INIS)

    Stepanova, Je.Yi.; Kolpakov, Yi.Je.; Zigalo, V.M.; And Others

    2015-01-01

    Total of 184 children were examined to determine the possible associative links between eNOS gene intron 4m polymorphism and indices characterizing the functional state of the endothelium and the bronchopulmonary system. Of them the main group of children consisted of 135 childrenresidents of radioactively contaminated areas, the control group - of 49 healthy children who lived in ''clean'' regions by the radioactive con tamination and were not belonging to victims of the Chernobyl accident contingents. The molecular genetic study determining the eNOS gene intron 4 polymorphism was performed. Children of the main group did not differ from that of control and literature data by the frequency of geno types 4a/b and eNOS gene allele polymorphism. An increase in the duration of circulation restoration up to the ini tial level after occlusion test was noted in children of the main group with genotype 4a/4b comparing to children with genotype 4b/4b ; a decrease in the nitrite content was observed in blood serum. The integral indices of elastic ity and tensility of the lung tissue, respiratory permeability were decreased; the signs of bronchospasm were record ed 1.5 times more often. These adverse effects were associated with the presence of genotype allele 4a , the signs of endothelial dysfunction and the level of the incorporated 137 Cs. More pronounced changes in vascular endothelial reaction to occlusion and the significant decrease of serum nitrite level in allele 4a carriers, especially in children who live in adverse ecological conditions, give the right to include them into the risk group for the development of endothelial dysfunction, and to conside pulmonary dysfunction as one of its manifestations

  17. Estrogen and phytoestrogens: Effect on eNOS expression and in vitro vasodilation in cerebral arteries in ovariectomized Watanabe heritable hyperlipidemic rabbits

    DEFF Research Database (Denmark)

    Lund, Claus O.; Mortensen, Alicja; Nilas, Lisbeth

    2007-01-01

    Objectives: To evaluate the effect of estrogen replacement therapy or soy isoflavones supplement on endothelium-dependent relaxation in vitro and gene expression of endothelial nitric oxide synthase (eNOS) in cerebral arteries in a rabbit model of human hypercholesterolemia. Study design: Thirty...... cholesterol was significantly higher at termination in the SoyLife(R) group (P lipoprotein (LDL) cholesterol was comparable in all treatment groups. Neither treatment influenced the endothelium-dependent responses to carbamylcholine chloride or L-NAME or the endothelium...

  18. Influencia del fenómeno ENOS (El Niño y La Niña) en la disponibilidad de grados-día

    OpenAIRE

    Lozada García, Beatriz; Prela, Angélica; Sentelhas, Paulo

    2004-01-01

    Se evaluó la influencia del fenómeno ENOS (El Niño y La Niña) sobre la disponibilidad de calor, en 8 localidades, ubicadas en la región centro-occidental de Venezuela, utilizando concepto de grados-día (GD). Los cambios de la temperatura, representados por las variaciones en los GD, afectarían directamente el ciclo fenológico los cultivos, generando un incremento o reducción en función de desvíos positivos o negativos, respectivamente. Los GD estimados fueron agrupados según el evento predomi...

  19. Relationship of the MTHFD1 (rs2236225, eNOS (rs1799983, CBS (rs2850144 and ACE (rs4343 gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects

    Directory of Open Access Journals (Sweden)

    Mehri Khatami

    2017-09-01

    Full Text Available Congenital heart defects are structural cardiovascular malformations that arise from abnormal formation of the heart or major blood vessels during the fetal period. To investigate the association of 4 single nucleotide polymorphisms (SNPs in the MTHFD1, eNOS, CBS and ACE genes, we evaluated their relationship with CHD in Iranian patients. In this case–control study, a total of 102 children with CHD and 98 control children were enrolled. Four SNPs including MTHFD1 G1958A, eNOS G894T, CBS C-4673G and ACE A2350G were genotyped by PCR-SSCP, Multiplex ARMS PCR and PCR-RFLP methods and confirmed by direct sequencing. We genotyped 102 patients and 98 controls for four polymorphisms by statistically analysis. There were three SNPs including MTHFD1 G1958A, eNOS G894T and ACE A2350G which might increase the risk of CHD, but CBS C-4673G was not significantly different between patients and controls. (P = 0.017, P = 0.048, P = 0.025 and P = 0.081 respectively. The allele frequencies of three SNPs for MTHFD1 G1958A, eNOS G894T and ACE A2350G in CHD are higher than that in control. Our results show that there is a significant relationship between MTHFD1 G1958A, eNOS G894T and ACE A2350G polymorphisms with CHD. Therefore, The AA and GA genotypes of MTHFD1 G1958A, TT and GT genotypes of eNOS G894T and the AA and GA genotypes of ACE A2350G are susceptible factors for CHD and may increase the risk of CHD.

  20. Relationship of the MTHFD1 (rs2236225), eNOS (rs1799983), CBS (rs2850144) and ACE (rs4343) gene polymorphisms in a population of Iranian pediatric patients with congenital heart defects.

    Science.gov (United States)

    Khatami, Mehri; Ratki, Farzaneh Morteza; Tajfar, Saba; Akrami, Fatemeh

    2017-09-01

    Congenital heart defects are structural cardiovascular malformations that arise from abnormal formation of the heart or major blood vessels during the fetal period. To investigate the association of 4 single nucleotide polymorphisms (SNPs) in the MTHFD1, eNOS, CBS and ACE genes, we evaluated their relationship with CHD in Iranian patients. In this case-control study, a total of 102 children with CHD and 98 control children were enrolled. Four SNPs including MTHFD1 G1958A, eNOS G894T, CBS C-4673G and ACE A2350G were genotyped by PCR-SSCP, Multiplex ARMS PCR and PCR-RFLP methods and confirmed by direct sequencing. We genotyped 102 patients and 98 controls for four polymorphisms by statistically analysis. There were three SNPs including MTHFD1 G1958A, eNOS G894T and ACE A2350G which might increase the risk of CHD, but CBS C-4673G was not significantly different between patients and controls. (P = 0.017, P = 0.048, P = 0.025 and P = 0.081 respectively). The allele frequencies of three SNPs for MTHFD1 G1958A, eNOS G894T and ACE A2350G in CHD are higher than that in control. Our results show that there is a significant relationship between MTHFD1 G1958A, eNOS G894T and ACE A2350G polymorphisms with CHD. Therefore, The AA and GA genotypes of MTHFD1 G1958A, TT and GT genotypes of eNOS G894T and the AA and GA genotypes of ACE A2350G are susceptible factors for CHD and may increase the risk of CHD. Copyright © 2017. Published by Elsevier Taiwan.

  1. Redox-sensitive up-regulation of eNOS by purple grape juice in endothelial cells: role of PI3-kinase/Akt, p38 MAPK, JNK, FoxO1 and FoxO3a.

    Directory of Open Access Journals (Sweden)

    Mahmoud Alhosin

    Full Text Available The vascular protective effect of grape-derived polyphenols has been attributable, in part, to their direct action on blood vessels by stimulating the endothelial formation of nitric oxide (NO. The aim of the present study was to determine whether Concord grape juice (CGJ, which contains high levels of polyphenols, stimulates the expression of endothelial NO synthase (eNOS in porcine coronary artery endothelial cells and, if so, to determine the signaling pathway involved. CGJ dose- and time-dependently increased eNOS mRNA and protein levels and this effect is associated with an increased formation of NO in endothelial cells. The stimulatory effect of CGJ on eNOS mRNA is not associated with an increased eNOS mRNA stability and inhibited by antioxidants such as MnTMPyP, PEG-catalase, and catalase, and by wortmannin (an inhibitor of PI3-kinase, SB 203580 (an inhibitor of p38 MAPK, and SP 600125 (an inhibitor of JNK. Moreover, CGJ induced the formation of reactive oxygen species (ROS in endothelial cells and this effect is inhibited by MnTMPyP, PEG-catalase, and catalase. The CGJ-induced the phosphorylation of p38 MAPK and JNK kinases is abolished by MnTMPyP. CGJ induced phosphorylation of transcription factors FoxO1 and FoxO3a, which regulate negatively eNOS expression, and this effect is prevented by MnTMPyP, PEG-catalase, wortmannin, SB203580 and SP600125. Moreover, chromatin immunoprecipitation assay indicated that the FoxO3a protein is associated with the eNOS promoter in control cells and that CGJ induced its dissociation. Thus, the present study indicates that CGJ up-regulates the expression of eNOS mRNA and protein leading to an increased formation of NO in endothelial cells. The stimulatory effect of CGJ is a redox-sensitive event involving PI3-kinase/Akt, p38 MAPK and JNK pathways, and the inactivation of the FoxO transcription factors, FoxO1 and FoxO3a, thereby preventing their repression of the eNOS gene.

  2. eNOS Glu298Asp polymorphism is associated with development of complicated plaques in patients from Serbia with advanced carotid atherosclerosis

    Directory of Open Access Journals (Sweden)

    Đurić Tamara

    2013-01-01

    Full Text Available Nitric oxide inhibits adhesion of thrombocytes, proliferation and migration of smooth muscle cells and restricts oxidation of atherogenic low-density lipoproteins. Therefore, decreased production or activity of NO may play a role in the initiation, progression or complications of atherosclerosis. The aim of this study was to estimate the effect of Glu298Asp eNOS gene polymorphism on the individual risk for development of complicated carotid atherosclerotic plaque in patients from Serbia with advanced carotid atherosclerosis (CA who had undergone endarterectomy. The study population included 233 patients. eNOS G894T gene polymorphism was identified by PCR and RFLP methods. Multivariate logistic regression analysis showed that Asp298Asp is an independent risk factor for the presence of complicated plaques in CA patients. Patients who were homozygous for the Asp298 allele had an adjusted OR of 4.36 for the development of complicated plaques compared to those that carry the Glu298 allele. Further validation and replication studies are needed. [Projekat Ministarstva nauke Republike Srbije, br. OI175085

  3. Vascular endothelial dysfunction in β-thalassemia occurs despite increased eNOS expression and preserved vascular smooth muscle cell reactivity to NO.

    Directory of Open Access Journals (Sweden)

    Ekatherina Stoyanova

    Full Text Available The hereditary β-thalassemia major condition requires regular lifelong blood transfusions. Transfusion-related iron overloading has been associated with the onset of cardiovascular complications, including cardiac dysfunction and vascular anomalies. By using an untransfused murine model of β-thalassemia major, we tested the hypothesis that vascular endothelial dysfunction, alterations of arterial structure and of its mechanical properties would occur despite the absence of treatments.Vascular function and structure were evaluated ex vivo. Compared to the controls, endothelium-dependent vasodilation with acetylcholine was blunted in mesenteric resistance arteries of β-thalassemic mice while the endothelium-independent vasodilator (sodium nitroprusside produced comparable vessel dilation, indicating endothelial cell impairment with preserved smooth muscle cell reactivity to nitric oxide (NO. While these findings suggest a decrease in NO bioavailability, Western blotting showed heightened expression of aortic endothelial NO synthase (eNOS in β-thalassemia. Vascular remodeling of the common carotid arteries revealed increased medial elastin content. Under isobaric conditions, the carotid arteries of β-thalassemic mice exhibited decreased wall stress and softening due to structural changes of the vessel wall.A complex vasculopathy was identified in untransfused β-thalassemic mice characterized by altered carotid artery structure and endothelial dysfunction of resistance arterioles, likely attributable to reduced NO bioavailability despite enhanced vascular eNOS expression.

  4. Differential effect of beetroot bread on postprandial DBP according to Glu298Asp polymorphism in the eNOS gene: a pilot study.

    Science.gov (United States)

    Hobbs, D A; George, T W; Lovegrove, J A

    2014-12-01

    Our objective was to investigate whether the presence of Glu298Asp polymorphism in the endothelial NO synthase (eNOS) gene differentially affects the postprandial blood pressure response to dietary nitrate-rich beetroot bread. A randomised, single-blind, controlled, crossover acute pilot study was performed in 14 healthy men (mean age: 34±9 years) who were retrospectively genotyped for Glu298Asp polymorphism (7GG; T carriers 7). Volunteers were randomised to receive 200 g beetroot-enriched bread (1.1 mmol nitrate) or control bread (no beetroot; 0.01 mmol nitrate) on two separate occasions 10 days apart. Baseline and incremental area under the curve of blood pressure and NOx (nitrate/nitrite) were measured for a 6-h postprandial period. A treatment × genotype interaction was observed for diastolic blood pressure (Pconsumption of beetroot bread compared with control bread. No significant differences were observed in the GG group. The beneficial diastolic blood pressure reduction was observed only in the T carriers of the Glu298Asp polymorphism in the eNOS gene after consumption of nitrate-rich beetroot bread. These data require confirmation in a larger population group.

  5. Hepatopulmonary syndrome induced by common bile duct ligation in a rabbit model: correlation between pulmonary vascular dilatation on thin-section CT and angiography and serum nitrite concentration or endothelial nitric oxide synthase (eNOS)1 expression

    International Nuclear Information System (INIS)

    Lee, Ki Nam; Yoon, Seong Kuk; Lee, Jin Wha; Kim, Ki Nam; Park, Byung Ho; Kwak, Jong Young; Jeong, Jin Sook; Kim, Young Hoon

    2004-01-01

    To investigate the correlation between radiologic vascular dilatation and serum nitrite concentration and eNOS expression in the endothelial cell and pneumocyte in a rabbit model of hepatopulmonary syndrome induced by common bile duct ligation (CBDL). Thin-section CT scans of the lung and pulmonary angiography were obtained 3 weeks after CBDL (n=6), or a sham operation (n=4), and intrapulmonary vasodilatation was assessed. The diameter and tortuosity of peripheral vessels in the right lower lobe by thin-section CT and angiography at the same level of the right lower lobe in all subjects were correlated to serum nitrite concentration and eNOS (endothelial nitric oxide synthase) expression as determined by immunostaining. The diameters of pulmonary vessels on thin-section CT were well correlated with nitrite concentrations in serum (r=0.92, ρ < 0.001). Dilated pulmonary vessels were significantly correlated with an increased eNOS expression (r=0.94, ρ < 0.0001), and the severity of pulmonary vessel tortuosity was found to be well correlated with serum nitrite concentration (r=0.90, ρ < 0.001). The peripheral pulmonary vasculature in hepatopulmonary syndrome induced by CBLD was dilated on thin-section CT and on angiographs. Our findings suggest that peripheral pulmonary vascular dilatations are correlated with serum nitrite concentrations and pulmonary eNOS expression

  6. L-Arginine ameliorates cardiac left ventricular oxidative stress by upregulating eNOS and Nrf2 target genes in alloxan-induced hyperglycemic rats

    International Nuclear Information System (INIS)

    Ramprasath, Tharmarajan; Hamenth Kumar, Palani; Syed Mohamed Puhari, Shanavas; Senthil Murugan, Ponniah; Vasudevan, Varadaraj; Selvam, Govindan Sadasivam

    2012-01-01

    Highlights: ► L-Arginine treatment reduced the metabolic disturbances in diabetic animals. ► Antioxidant marker proteins were found high in myocardium by L-arginine treatment. ► Elevated antioxidant status, mediates the reduced TBA-reactivity in left ventricle. ► L-Arginine treatment enhanced the Nrf2 and eNOS signaling in left ventricle. ► Improved cell survival signaling by arginine, offers a novel tactic for targeting. -- Abstract: Hyperglycemia is independently related with excessive morbidity and mortality in cardiovascular disorders. L-Arginine-nitric oxide (NO) pathway and the involvement of NO in modulating nuclear factor-E2-related factor-2 (Nrf2) signaling were well established. In the present study we investigated, whether L-arginine supplementation would improve the myocardial antioxidant defense under hyperglycemia through activation of Nrf2 signaling. Diabetes was induced by alloxan monohydrate (90 mg kg −1 body weight) in rats. Both non-diabetic and diabetic group of rats were divided into three subgroups and they were administered either with L-arginine (2.25%) or L-NAME (0.01%) in drinking water for 12 days. Results showed that L-arginine treatment reduced the metabolic disturbances in diabetic rats. Antioxidant enzymes and glutathione levels were found to be increased in heart left ventricles, thereby reduction of lipid peroxidation by L-arginine treatment. Heart histopathological analysis further validates the reversal of typical diabetic characteristics consisting of alterations in myofibers and myofibrillary degeneration. qRT-PCR studies revealed that L-arginine treatment upregulated the transcription of Akt and downregulated NF-κB. Notably, transcription of eNOS and Nrf2 target genes was also upregulated, which were accompanied by enhanced expression of Nrf2 in left ventricular tissue from diabetic and control rats. Under these findings, we suggest that targeting of eNOS and Nrf2 signaling by L-arginine supplementation could be

  7. L-Arginine ameliorates cardiac left ventricular oxidative stress by upregulating eNOS and Nrf2 target genes in alloxan-induced hyperglycemic rats

    Energy Technology Data Exchange (ETDEWEB)

    Ramprasath, Tharmarajan; Hamenth Kumar, Palani; Syed Mohamed Puhari, Shanavas; Senthil Murugan, Ponniah; Vasudevan, Varadaraj [Molecular Cardiology Unit, Department of Biochemistry, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, Tamilnadu (India); Selvam, Govindan Sadasivam, E-mail: drselvamgsbiochem@rediffmail.com [Molecular Cardiology Unit, Department of Biochemistry, Center for Excellence in Genomic Sciences, School of Biological Sciences, Madurai Kamaraj University, Madurai 625 021, Tamilnadu (India)

    2012-11-23

    Highlights: Black-Right-Pointing-Pointer L-Arginine treatment reduced the metabolic disturbances in diabetic animals. Black-Right-Pointing-Pointer Antioxidant marker proteins were found high in myocardium by L-arginine treatment. Black-Right-Pointing-Pointer Elevated antioxidant status, mediates the reduced TBA-reactivity in left ventricle. Black-Right-Pointing-Pointer L-Arginine treatment enhanced the Nrf2 and eNOS signaling in left ventricle. Black-Right-Pointing-Pointer Improved cell survival signaling by arginine, offers a novel tactic for targeting. -- Abstract: Hyperglycemia is independently related with excessive morbidity and mortality in cardiovascular disorders. L-Arginine-nitric oxide (NO) pathway and the involvement of NO in modulating nuclear factor-E2-related factor-2 (Nrf2) signaling were well established. In the present study we investigated, whether L-arginine supplementation would improve the myocardial antioxidant defense under hyperglycemia through activation of Nrf2 signaling. Diabetes was induced by alloxan monohydrate (90 mg kg{sup -1} body weight) in rats. Both non-diabetic and diabetic group of rats were divided into three subgroups and they were administered either with L-arginine (2.25%) or L-NAME (0.01%) in drinking water for 12 days. Results showed that L-arginine treatment reduced the metabolic disturbances in diabetic rats. Antioxidant enzymes and glutathione levels were found to be increased in heart left ventricles, thereby reduction of lipid peroxidation by L-arginine treatment. Heart histopathological analysis further validates the reversal of typical diabetic characteristics consisting of alterations in myofibers and myofibrillary degeneration. qRT-PCR studies revealed that L-arginine treatment upregulated the transcription of Akt and downregulated NF-{kappa}B. Notably, transcription of eNOS and Nrf2 target genes was also upregulated, which were accompanied by enhanced expression of Nrf2 in left ventricular tissue from diabetic

  8. eNOS se correlaciona com a biogênese mitocondrial em corações com cardiopatia congênita e cianose

    Directory of Open Access Journals (Sweden)

    Juan Xiao

    2012-09-01

    Full Text Available FUNDAMENTO: O programa de biogênese mitocondrial no coração parece apresentar remodelação adaptativa após estresse biomecânico e oxidativo. Os mecanismos adaptativos que protegem o metabolismo do miocárdio durante a hipóxia são coordenados, em parte, pelo óxido nítrico (NO. OBJETIVO: Observar a biogênese mitocondrial e expressão do óxido nítrico sintase (NOS em corações de cardiopatia congênita com cianose; discutir a resposta mitocondrial à hipóxia crônica do miocárdio. MÉTODOS: Foram investigados 20 pacientes com defeitos cardíacos cianóticos (n = 10 ou acianóticos (n = 10. Foram estudadas amostras do miocárdio na via de saída ventricular direita, tomadas durante a operação. A análise morfométrica de mitocôndrias foi realizada por microscopia eletrônica de transmissão. A relação mtDNA/nDNA foi determinada com PCR em tempo real. Os níveis de transcrição da subunidade I da citocromo c oxidase (COXI, coativador-1α do receptor γ ativado por proliferador de peroxissoma (PGC-1α, o fator respiratório nuclear 1 (NRF1, e fator de transcrição mitocondrial A (Tfam foram detectados por reação em cadeia da polimerase via transcriptase reversa (RT-PCR ativado por fluorescência em tempo real. Os níveis proteicos de COXI e nNOS, iNOS e eNOS foram medidos por técnica de Western Blot. RESULTADOS: A densidade volumétrica mitocondrial (Vv e a densidade numérica (Nv foram significativamente elevadas em pacientes com cianose, em comparação com a cardiopatia congênita acianótica. MtDNA elevada e suprarregulação dos níveis de COXI, PGC-1 α, NRF1 e Tfam mRNA foram observadas em pacientes cianóticos. Os níveis de proteína de COXI e eNOS foram significativamente maiores no miocárdio de pacientes cianóticos que nos de acianóticos. Os níveis de transcrição do PGC-1α se correlacionam com os níveis de eNOS. CONCLUSÃO: A biogênese mitocondrial é ativada no miocárdio da via de saída ventricular na

  9. Age and gender differences in the influences of eNOS T-786C polymorphism on arteriosclerotic parameters in general population in Japan.

    Science.gov (United States)

    Hashimoto, Marowa; Miyai, Nobuyuki; Hattori, Sonomi; Iwahara, Akihiko; Utsumi, Miyoko; Arita, Mikio; Takeshita, Tatsuya

    2016-07-01

    The influence of T-786C polymorphism in the promoter region of endothelial nitric oxide synthase (eNOS) on arteriosclerotic parameters by age and gender were examined. Brachial-ankle pulse wave velocity (baPWV), heart-rate adjusted augmentation index (AIx@75), pulse pressure (PP) and albumin-creatinine ratio (ACR) were assessed as arteriosclerotic parameters in addition to non-high-density lipoprotein cholesterol (non-HDL-C) to HDL-C (non-HDL-C/HDL-C) ratio in 1499 participants. T-786C polymorphism (rs2070744) was screened using a TaqMan allelic discrimination assay. Analyses of covariance were carried. Women with the non-C allele showed significantly lower AIx@75 in participants aged gender differences, possibly involving antioxidative and/or endothelial signaling other than inflammatory signaling.

  10. H2O2 Treatment of HUVECs Facilitates PKC Mediated Thr495 Phosphorylation on eNOS when Pre-treated with High Glucose Levels

    DEFF Research Database (Denmark)

    Guterbaum, Thomas J; Braunstein, Thomas H; Fossum, Anna

    2015-01-01

    Objective: Metabolic syndrome entails hypertension, hyperglycemia, obesity and hypercholesterolemia. This syndrome increases the risk of cardiovascular disease and diabetes. Hyperglycemia during coronary reperfusion is associated with a poor prognosis. Contrastingly, targeting correction of hyper......Objective: Metabolic syndrome entails hypertension, hyperglycemia, obesity and hypercholesterolemia. This syndrome increases the risk of cardiovascular disease and diabetes. Hyperglycemia during coronary reperfusion is associated with a poor prognosis. Contrastingly, targeting correction....... The presence of reactive oxygen species (ROS) in both mitochondria and cytoplasm was measured by fluorescence activated cell sorting (FACS). Phosphorylation of endothelial nitric oxide synthase (eNOS) on threonine 495 (Thr495) and serine 1177 (Ser1177) was assessed by western blotting. Short-term (20 hours...

  11. 2,4,6-Tri-amino-1,3,5-triazin-1-ium 3-(prop-2-eno-yloxy)propano-ate acrylic acid monosolvate monohydrate.

    Science.gov (United States)

    Sangeetha, V; Kanagathara, N; Chakkaravarthi, G; Marchewka, M K; Anbalagan, G

    2013-05-01

    The asymmetric unit of the title salt, C3H7N6 (+)·C6H7O4 (-)·C3H4O2·H2O, contains a 2,4,6-tri-amino-1,3,5-triazin-1-ium cation, a 3-(prop-2-eno-yloxy)propano-ate anion and acrylic acid and water solvent mol-ecules in a 1:1:1:1 ratio and with each species in a general position. In the crystal, the components are linked into a supra-molecular layer in the bc plane via a combination of O-H⋯O, N-H⋯N and N-H⋯O hydrogen bonding. The crystal studied was a non-merohedral twin, the minor component contribution being approximately 26%.

  12. Treadmill exercise alleviates diabetic cardiomyopathy by suppressing plasminogen activator inhibitor expression and enhancing eNOS in streptozotocin-induced male diabetic rats.

    Science.gov (United States)

    Chengji, Wang; Xianjin, Fan

    2018-04-01

    To investigate the biological mechanism of the effect of different intensity exercises on diabetic cardiomyopathy. 87 raise specific pathogen SPF healthy 6-week-old male Sprague-Dawley rats, fed 6 weeks with high-fat diet for rats were used, and a diabetic model was established by intraperitoneal injection of streptozotocin - randomly selected 43 rats were divided into Diabetic control group (DCG, n  = 10), Diabetic exercise group 1 (DEG1, n  = 11), Diabetic exercise group 2 (DEG2, n  = 11) and Diabetic exercise group 3 (DEG3, n  = 11). The rats in DEG1 were forced to run on a motorized treadmill, the exercise load consisted of running at a speed of 10 m/min, the exercise load of the rats in DEG2 were running at a speed of 15 m/min, the exercise load of the rats in DEG3 were running at a speed of 20 m/min, for one hour once a day for 6 weeks. After 6 weeks of exercise intervention, glucose metabolism-related indexes in rats such as blood glucose (FBG), glycosylated serum protein (GSP) and insulin (FINS); cardiac fibrinolytic system parameters such as PAI-1 (plasminogen activator inhibitor 1), Von Willebrand factor (vWF), protein kinase C (PKC) and diacylglycerol (DAG); and serum level of NO, eNOS and T-NOS were measured. Compared with DCG, fasting blood glucose and GSP were decreased, while insulin sensitivity index and insulin level were increased in all rats of the three exercise groups. FBG decrease was statistically significant ( P  diabetic rats; myocardial PAI-1 in DEG1, DEG2 and DEG3 rats decreased significantly ( P  diabetic cardiomyopathy by affecting the levels of PAI-1 and eNOS, and there is a dependence on intensity. © 2018 The authors.

  13. San-Huang-Xie-Xin-Tang Prevents Rat Hearts from Ischemia/Reperfusion-Induced Apoptosis through eNOS and MAPK Pathways

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    Shu-Fen Liou

    2011-01-01

    Full Text Available San-Huang-Xie-Xin-Tang (SHXT is a traditional Chinese medication consisting of three herbs, namely Coptidis rhizome, Scutellariae radix and Rhei rhizome. This study aimed to examine the cardioprotective effects of SHXT in a rat model of acute myocardial apoptosis induced by ischemia/reperfusion (I/R. Vehicle (intravenous saline or SHXT (intravenous or oral was administered prior to I/R (occlusion of left coronary artery for 45 min followed by reperfusion for 2 h. In the vehicle group, myocardial I/R caused myocardial infarction with increased plasma cardiac enzymes, severe arrhythmia and mortality. Myocardial apoptosis was induced by I/R as evidenced by DNA ladder and Bcl-2/Bax ratio. In the SHXT group, we found that SHXT significantly reduced plasma levels of cardiac enzymes, arrhythmia scores (from 5 ± 1 to 2 ± 1, P<.01 and mortality rate (from 53 to 0%, P<.01. In addition, pretreatment with intravenous SHXT reduced the infarct size dose-dependently when compared with the vehicle group (10 mg kg−1: 14.0 ± 0.2 versus 44.5 ± 5.0%, and 30 mg kg−1: 6.2 ± 1.2% versus 44.5 ± 5.0%, both P<.01. Similarly, oral administration of SHXT reduced the infarct size dose-dependently. Furthermore, SHXT markedly decreased the apoptosis induced by I/R with increased Bcl-2/Bax ratio. Finally, we found that SHXT counteracted the I/R-induced downstream signaling, resulting in increased myocardial eNOS expression and plasma nitrite, and decreased activation of ERK1/2, p38 and JNK. These data suggest that SHXT has cardioprotective effects against I/R-induced apoptosis, and that these effects are mediated, at least in part, by eNOS and MAPK pathways.

  14. Role of C677T and A1298C MTHFR, A2756G MTR and -786 C/T eNOS gene polymorphisms in atrial fibrillation susceptibility.

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    Betti Giusti

    Full Text Available BACKGROUND: Hyperhomocysteinemia has been suggested to play a role in the NonValvular Atrial Fibrillation (NVAF pathogenesis. Polymorphisms in genes coding for homocysteine (Hcy metabolism enzymes may be associated with hyperhomocysteinemia and NVAF. METHODOLOGIES: 456 NVAF patients and 912 matched controls were genotyped by an electronic microchip technology for C677T and A1298C MTHFR, A2756G MTR, and -786C/T eNOS gene polymorphisms. Hcy was determined by an immunoassay method. PRINCIPAL FINDINGS: The genotype distribution of the four polymorphisms as well as genotype combinations did not differ in patients and controls. Hcy was higher in patients than in controls (15.2, 95%CI 14.7-15.7 vs 11.3, 95%CI 11.0-11.6 micromol/L; p<0.0001. In both populations, a genotype-phenotype association (p<0.0001 between Hcy and C677T MTHFR polymorphism was observed; in controls a significant (p = 0.029 association between tHcy and -786C/T eNOS polymorphism was also observed. At the multivariate analysis the NVAF risk significantly increased in the upper quartiles of Hcy compared to the lowest: OR from 2.8 (1.68-4.54 95%CI in Q2 to 12.9 (7.96-21.06 95%CI in Q4. CONCLUSIONS: Our data demonstrated the four polymorphisms, although able, at least in part, to affect Hcy, were not associated with an increased risk of NVAF per se or in combination.

  15. Dual-Specificity Phosphatase 4 Overexpression in Cells Prevents Hypoxia/Reoxygenation-Induced Apoptosis via the Upregulation of eNOS

    Science.gov (United States)

    Dougherty, Julie A.; Kilbane Myers, Joanna; Khan, Mahmood; Angelos, Mark G.; Chen, Chun-An

    2017-01-01

    Mitogen-activated protein kinases (MAPKs) signaling cascades regulate several cellular functions, including differentiation, proliferation, survival, and apoptosis. The duration and magnitude of phosphorylation of these MAPKs are decisive determinants of their physiological functions. Dual-specificity phosphatases exert kinetic control over these signaling cascades. Previously, we demonstrated that DUSP4−/− hearts sustain a larger infarct and have poor functional recovery, when isolated hearts were subjected to ischemia/reperfusion. Uncontrolled p38 activation and upregulation of Nox4 expression are the main effectors for this functional alteration. Here, dual-specificity phosphatase 4 (DUSP4) overexpression in endothelial cells was used to investigate the role of DUSP4 on the modulation of reactive oxygen species (ROS) generation and vascular function, when cells were subjected to hypoxia/reoxygenation (H/R) insult. Immunostaining with cleaved caspase-3 revealed that DUSP4 overexpression prevents caspase-3 activation and apoptosis after H/R. The beneficial effects occur via modulating p38 activity, increased NO bioavailability, and reduced oxidative stress. More importantly, DUSP4 overexpression upregulates eNOS protein expression (1.62 ± 0.33 versus 0.65 ± 0.16) during H/R-induced stress. NO is a critical small molecule involved in regulating vascular tone, vascular growth, platelet aggregation, and modulation of inflammation. The level of NO generation determined using DAF-2 fluorescence demonstrated that DUSP4 overexpression augments NO production and thus improves vascular function. The level of superoxide generated from cells after being subjected to H/R was determined using dihydroethidium-HPLC method. The results suggested that DUSP4 overexpression in cells decreases H/R-induced superoxide generation (1.56 ± 0.14 versus 1.19 ± 0.05) and thus reduces oxidant stress. This also correlates with the reduction in the total protein S

  16. Obesity, inflammation, and exercise training: relative contribution of iNOS and eNOS in the modulation of vascular function in the mouse aorta

    Directory of Open Access Journals (Sweden)

    Josiane Fernandes da Silva

    2016-09-01

    Full Text Available Background - The understanding of obsesity-related vascular dysfunction remains controversial mainly because of the diseases associated with vascular injury. Exercise training is known to prevent vascular dysfunction. Using an obesity model without comorbidities, we aimed at investigating the underlying mechanism of vascular dysfunction and how exercise interferes with this process.Methods - High-sugar diet was used to induce obesity in mice. Exercise training was performed 5 days/week. Body weight, energy intake, and adipose tissues were assessed; blood metabolic and hormonal parameters were determined; and serum TNFα was measured. Blood pressure and heart rate were assessed by plethysmography. Changes in aortic isometric tension were recorded on myograph. Western blot was used to analyze protein expression. Nitric oxide (NO was evaluated using fluorescence microscopy. Antisense oligodeoxynucleotides were used for inducible nitric oxide synthase isoform (iNOS knockdown.Results - Body weight, fat mass, total cholesterol, low-density lipoprotein cholesterol fraction, insulin, and leptin were higher in the sedentary obese group (SD than in the sedentary control animals (SS. Exercise training prevented these changes. No difference in glucose tolerance, insulin sensitivity, blood pressure, and heart rate was found. Decreased vascular relaxation and reduced endothelial nitric oxide synthase (eNOS functioning in the SD group were prevented by exercise. Contractile response to phenylephrine was decreased in the aortas of the wild SD mice, compared with that of the SS group; however, no alteration was noted in the SD iNOS-/- animals. The decreased contractility was endothelium-dependent, and was reverted by iNOS inhibition or iNOS silencing. The aortas from the SD group showed increased basal NO production, serum TNFα, TNF receptor-1, and phospho-IκB. Exercise training attenuated iNOS-dependent reduction in contractile response in high-sugar diet

  17. Effects of stimulation of soluble guanylate cyclase on diabetic nephropathy in diabetic eNOS knockout mice on top of angiotensin II receptor blockade.

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    Ina M Ott

    Full Text Available The prevalence of diabetes mellitus and its complications, such as diabetic nephropathy (DN, is rising worldwide and prevention and treatment are therefore becoming increasingly important. Therapy of DN is particularly important for patients who do not adequately respond to angiotensin receptor blocker (ARB treatment. Novel approaches include the stimulation of soluble guanylate cyclase (sGC as it is reported to have beneficial effects on cardiac and renal damage. We aimed to investigate the effects of the sGC stimulator riociguat and ARB telmisartan on kidney function and structure in a hypertensive model of diabetic nephropathy. Seventy-six diabetic male eNOS knockout C57BL/6J mice were randomly divided after having received streptozotocin: telmisartan (1 mg/kg/d, riociguat (3 mg/kg/d, riociguat+telmisartan (3+1 mg/kg/d, and vehicle. Fourteen mice were used as non-diabetic controls. Treatment duration was 11 weeks. Glucose concentrations were increased and similar in all diabetic groups. Telmisartan insignificantly reduced blood pressure by 5.9 mmHg compared with diabetic controls (111.2±2.3 mmHg vs. 117.1±2.2 mmHg; p = 0.071. Treatment with riociguat both alone and in combination with telmisartan led to a significant reduction of blood pressure towards diabetic vehicle (105.2±2.5 mmHg and 105.0±3.2 mmHg, respectively, vs. 117.1±2.2 mmHg. Combined treatment also significantly decreased albuminuria compared with diabetic controls (47.3±9.6 µg/24 h vs. 170.8±34.2 µg/24 h; p = 0.002 reaching levels similar to those of non-diabetic controls (34.4±10.6 µg/24 h, whereas the reduction by single treatment with either telmisartan (97.8±26.4 µg/24 h or riociguat (97.1±15.7 µg/24 h was not statistically significant. The combination treatment led to a significant (p<0.01 decrease of tissue immunoreactivity of malondialdehyde, as consequence of reduced oxidative stress. In conclusion, stimulation of sGC significantly reduced urinary

  18. Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats

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    Thewarid Berkban

    2015-06-01

    Full Text Available The effect of ellagic acid on oxidative stress and hypertension induced by Nω-Nitro-l-arginine methyl ester hydrochloride (L-NAME was investigated. Male Sprague-Dawley rats were administrated with L-NAME (40 mg/kg/day for five weeks. L-NAME induced high systolic blood pressure (SBP and increased heart rate (HR, hindlimb vascular resistance (HVR and oxidative stress. Concurrent treatment with ellagic acid (7.5 or 15 mg/kg prevented these alterations. Co-treatment with ellagic acid was associated with up-regulation of endothelial nitric oxide synthase (eNOS protein production and alleviation of oxidative stress as indicated by decreased superoxide production in the vascular tissue, reduced plasma malondialdehyde levels, reduced NADPH oxidase subunit p47phox expression and increased plasma nitrate/nitrite levels. Our results indicate that ellagic acid attenuates hypertension by reducing NADPH oxidase subunit p47phox expression, which prevents oxidative stress and restores NO bioavailability.

  19. Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in l-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT1R Expression

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    Putcharawipa Maneesai

    2016-02-01

    Full Text Available This study examined the effect of Carthamus tinctorius (CT extract plus captopril treatment on blood pressure, vascular function, nitric oxide (NO bioavailability, oxidative stress and renin-angiotensin system (RAS in Nω-Nitro-l-arginine methyl ester (l-NAME-induced hypertension. Rats were treated with l-NAME (40 mg/kg/day for five weeks and given CT extract (75 or 150 or 300 or 500 mg/kg/day: captopril (5 mg/kg/day or CT extract (300 mg/kg/day plus captopril (5 mg/kg/day for two consecutive weeks. CT extract reduced blood pressure dose-dependently, and the most effective dose was 300 mg/kg/day. l-NAME-induced hypertensive rats showed abnormalities including high blood pressure, high vascular resistance, impairment of acetylcholine-induced vasorelaxation in isolated aortic rings and mesenteric vascular beds, increased vascular superoxide production and plasma malondialdehyde levels, downregulation of eNOS, low level of plasma nitric oxide metabolites, upregulation of angiotensin II type 1 receptor and increased plasma angiotensin II. These abnormalities were alleviated by treatment with either CT extract or captopril. Combination treatment of CT extract and captopril normalized all the abnormalities found in hypertensive rats except endothelial dysfunction. These data indicate that there are synergistic antihypertensive effects of CT extract and captopril. These effects are likely mediated by their anti-oxidative properties and their inhibition of RAS.

  20. Influence of training status and eNOS haplotypes on plasma nitrite concentrations in normotensive older adults: a hypothesis-generating study.

    Science.gov (United States)

    da Silva, Roberta Fernanda; Sertório, Jonas Tadeu Cau; Lacchini, Riccardo; Trapé, Atila Alexandre; Tanus-Santos, José Eduardo; Rush, James W E; Amaral, Sandra Lia; Zago, Anderson Saranz

    2014-12-01

    The purpose of this study was to evaluate the relationship between 3 eNOS gene polymorphisms and training status (TS) in affecting plasma nitrite concentration (NO2) in normotensive adults over 50 years old. Resting blood pressure (BP) was measured in all participants (n = 101). Plasma was taken to analyze: lipid profile, nitrite concentration (NO2) and lipid peroxide levels (T-BARS). Also, genomic DNA was extracted from plasma for genotyping NOS3 polymorphisms (-786T>C; 894G>T; and VNTR in intron 4). TS was determined by one-mile walk test and Functional Fitness Test Battery from AAHPERD (TS1-regular TS; TS2-good TS; and TS3-very good TS). BP was not influenced by TS, but NO2 was 15% higher in TS3 (123 ± 27 nM) compared to TS-2 (106 ± 22 nM). No differences were found in plasma NO2 in the haplotype analyses. However, the presence of the C allele (T-786C) and ASP allele (Glu298Asp) was found to enhance the correlation between TS and NO2 levels (r = 0.492 in C/4b/ASP haplotype and r = 0.855 in C/4a/ASP haplotype). This study thus identifies NOS3 polymorphism-dependent sensitivity to the effects of physical training on plasma NO2. Maintenance of good levels of training status, in carriers of C allele for T-786C polymorphism, combined with ASP allele for Glu298Asp polymorphism, may result in an increase in the NO2 plasma concentrations, which may reflect improved NO bioavailability in older adult normotensive individuals.

  1. A combination of genistein and magnesium enhances the vasodilatory effect via an eNOS pathway and BK(Ca) current amplification.

    Science.gov (United States)

    Sun, Lina; Hou, Yunlong; Zhao, Tingting; Zhou, Shanshan; Wang, Xiaoran; Zhang, Liming; Yu, Guichun

    2015-04-01

    The phytoestrogen genistein (GST) and magnesium have been independently shown to regulate vascular tone; however, their individual vasodilatory effects are limited. The aim of this study was to examine the combined effects of GST plus magnesium on vascular tone in mesenteric arteries. The effects of pretreatment with GST (0-200 μmol/L), MgCl2 (0-4.8 mmol/L) and GST plus MgCl2 on 10 μmol/L phenylephrine (PE) precontracted mesenteric arteries in rats were assessed by measuring isometric force. BK(Ca) currents were detected by the patch clamp method. GST caused concentration- and partial endothelium-dependent relaxation. Magnesium resulted in dual adjustment of vascular tone. Magnesium-free solution eliminated the vasodilatation of GST in both endothelium-intact and denuded rings. GST (50 μmol/L) plus magnesium (4.8 mmol/L) caused stronger relaxation in both endothelium-intact and denuded rings. Pretreatment with the nitric oxide synthase (NOS) inhibitor L-N-nitroarginine methyl ester (L-NAME, 100 μmol/L) significantly inhibited the effects of GST, high magnesium, and the combination of GST and magnesium. BK(Ca) currents were amplified to a greater extent when GST (50 μmol/L) was combined with 4.8 versus 1.2 mmol/L Mg(2+). Our data suggest that GST plus magnesium provides enhanced vasodilatory effects in rat mesenteric arteries compared with that observed when either is used separately, which was related to an eNOS pathway and BK(Ca) current amplification.

  2. MicroRNA-27b plays a role in pulmonary arterial hypertension by modulating peroxisome proliferator-activated receptor γ dependent Hsp90-eNOS signaling and nitric oxide production

    Energy Technology Data Exchange (ETDEWEB)

    Bi, Rui; Bao, Chunrong; Jiang, Lianyong; Liu, Hao; Yang, Yang; Mei, Ju; Ding, Fangbao, E-mail: dbcar126@126.com

    2015-05-01

    Pulmonary artery endothelial dysfunction is associated with pulmonary arterial hypertension (PAH). Based on recent studies showing that microRNA (miR)-27b is aberrantly expressed in PAH, we hypothesized that miR-27b may contribute to pulmonary endothelial dysfunction and vascular remodeling in PAH. The effect of miR-27b on pulmonary endothelial dysfunction and the underlying mechanism were investigated in human pulmonary artery endothelial cells (HPAECs) in vitro and in a monocrotaline (MCT)-induced model of PAH in vivo. miR-27b expression was upregulated in MCT-induced PAH and inversely correlated with the levels of peroxisome proliferator-activated receptor (PPAR)-γ, and miR-27b inhibition attenuated MCT-induced endothelial dysfunction and remodeling and prevented PAH associated right ventricular hypertrophy and systolic pressure in rats. PPARγ was confirmed as a direct target of miR-27b in HPAECs and shown to mediate the effect of miR-27b on the disruption of endothelial nitric oxide synthase (eNOS) coupling to Hsp90 and the suppression of NO production associated with the PAH phenotype. We showed that miR-27b plays a role endothelial function and NO release and elucidated a potential mechanism by which miR-27b regulates Hsp90-eNOS and NO signaling by modulating PPARγ expression, providing potential therapeutic targets for the treatment of PAH. - Highlights: • miR-27b plays a role in endothelial function and NO release. • miR-27b inhibition ameliorates MCT-induced endothelial dysfunction and PAH. • miR-27b targets PPARγ in HPAECs. • miR-27b regulates PPARγ dependent Hsp90-eNOS and NO signaling.

  3. Impacto del ENOS sobre los rendimientos de maíz en la región pampeana argentina Impact of the ENSO on corn yields in the Argentinean pampas region

    Directory of Open Access Journals (Sweden)

    M. E. Fernández Long

    2011-06-01

    Full Text Available El fenómeno de “El Niño - Oscilación del Sur” (ENOS es uno de los principales responsables de la variabilidad climática interanual, con influencia sobre la región pampeana argentina. El objetivo de este trabajo fue analizar el impacto del ENOS sobre las variaciones anuales de la producción de maíz. La región fue dividida en 10 zonas en las cuales los rendimientos tienen una variabilidad interanual homogénea. Se utilizaron diferentes índices del ENOS. Los resultados indicaron que, en la mayor parte de la región, los desvíos de los rendimientos son, en general, positivos durante eventos “El Niño” y negativos durante “La Niña”. Sin embargo, el impacto es muy fuerte al norte y centro de la región analizada, y se debilita hacia el sur. En el sudeste de la provincia de Buenos Aires el comportamiento es diferente que en el resto. Los índices promediados de mayo a julio son, en general, un buen indicador de la influencia del ENOS sobre la productividad de los cultivos, y brindan una adecuada información para la toma de decisiones de la empresa agropecuaria, con suficiente anticipación respecto del comienzo de la campaña.The “El Niño Southern Oscillation” (ENSO phenomenon is one of the main responsible factor for interannual climate variability in the “pampas” region. This work aims to analyze the impact of ENSO on the annual variations of corn production. The region was divided into 10 areas in which yields have a homogeneous interannual variability. Five ENSO indexes were used The results indicated that, in most parts of the region, the deviations of trend line yields are, in general, positive during “El Niño” events and negative during “La Niña”. However, the impact is very strong in the North and Centre of the analyzed region and weakens southward. In the southeast of the province of Buenos Aires, the behavior is different than the rest. Averaging indexes from May to July we obtained a good indicator

  4. Puruvana puruvanavana : [luuletused] / Eno Raud

    Index Scriptorium Estoniae

    Raud, Eno, 1928-1996

    2000-01-01

    Sisu: Puruvana puruvanavana ; Vetesell ; Pada ja katel ; Nääripäkapikk ; Vanapaar ; Mere peremees ; Lepamaim ; Kiilaspää kiilasjääl ; Tõugu unistus ; Naljatilk silk ; Muttide jalutuskäik ; Hiir lumes ; Kalakari salakaril ; Naljalammas ; Mesilastest ; Kure mure ; Voki laul karule ; Põrsalaul ; Kurk ja kõrvits ; Tuhk ja tina ; Õige pea ja vale pea ; Suu pea, puupea! ; Siga õuel

  5. Efeitos da atorvastatina e do polimorfismo T-786C do gene eNOS sobre parâmetros do metabolismo lipídico plasmático

    Directory of Open Access Journals (Sweden)

    Vanessa Helena de Souza Zago

    2013-01-01

    Full Text Available FUNDAMENTO: A atividade do óxido nítrico sintase endotelial (eNOS pode ser modulada pelo colesterol da lipoproteína de alta densidade (HDL-C, estatinas ou polimorfismos, como o T-786C de eNOS. OBJETIVO: Este estudo teve como objetivo avaliar se o polimorfismo T-786C está associado a alterações nos efeitos da atorvastatina no perfil lipídico, nas concentrações de metabólitos de óxido nítrico (NO e da proteína C reativa de alta sensibilidade (PCR-as. MÉTODOS: Trinta voluntários do sexo masculino, assintomáticos, com idade entre 18-56 anos foram genotipados e classificados de acordo com a ausência (TT, n = 15 ou presença (CC, n = 15 do polimorfismo. Eles foram selecionados aleatoriamente para a utilização de placebo e atorvastatina (10 mg/dia por 14 dias. Após cada tratamento foram medidos lípides, lipoproteínas, frações HDL2 e HDL3, atividade da proteína de transferência de colesteril éster (CETP, metabólitos de NO e PCR-as. RESULTADOS: As comparações entre genótipos após a administração de placebo mostraram aumento da atividade da CETP polimorfismo-dependente (TT, 12 ± 7; CC, 22 ± 12, p < 0,05. As análises da interação entre os tratamentos indicaram que a atorvastatina tem efeito sobre colesterol, LDL, nitrito e razões lípides/proteínas (HDL2 e HDL3 (p < 0,001 em ambos os genótipos. É interessante notar as interações genótipo/droga sobre a CETP (p < 0,07 e a lipoproteína (a [Lp(a] (p < 0,056, levando a uma diminuição limítrofe da CETP, embora sem afetar a Lp(a. A PRC-as não mostrou alterações. CONCLUSÃO: Os resultados sugerem que o tratamento com estatinas pode ser relevante para a prevenção primária da aterosclerose em pacientes com o polimorfismo T-786C do eNOS, considerando os efeitos no metabolismo lipídico.

  6. 2,4,6-Tri­amino-1,3,5-triazin-1-ium 3-(prop-2-eno­yloxy)propano­ate acrylic acid monosolvate monohydrate

    Science.gov (United States)

    Sangeetha, V.; Kanagathara, N.; Chakkaravarthi, G.; Marchewka, M. K.; Anbalagan, G.

    2013-01-01

    The asymmetric unit of the title salt, C3H7N6 +·C6H7O4 −·C3H4O2·H2O, contains a 2,4,6-tri­amino-1,3,5-triazin-1-ium cation, a 3-(prop-2-eno­yloxy)propano­ate anion and acrylic acid and water solvent mol­ecules in a 1:1:1:1 ratio and with each species in a general position. In the crystal, the components are linked into a supra­molecular layer in the bc plane via a combination of O—H⋯O, N—H⋯N and N—H⋯O hydrogen bonding. The crystal studied was a non-merohedral twin, the minor component contribution being approximately 26%. PMID:23723892

  7. The Streptococcus pyogenes Serotype M49 Nra-Ralp3 Transcriptional Regulatory Network and Its Control of Virulence Factor Expression from the Novel eno ralp3 epf sagA Pathogenicity Region▿ †

    Science.gov (United States)

    Kreikemeyer, Bernd; Nakata, Masanobu; Köller, Thomas; Hildisch, Hendrikje; Kourakos, Vassilios; Standar, Kerstin; Kawabata, Shigetada; Glocker, Michael O.; Podbielski, Andreas

    2007-01-01

    Many Streptococcus pyogenes (group A streptococcus [GAS]) virulence factor- and transcriptional regulator-encoding genes cluster together in discrete genomic regions. Nra is a central regulator of the FCT region. Previous studies exclusively described Nra as a transcriptional repressor of adhesin and toxin genes. Here transcriptome and proteome analysis of a serotype M49 GAS strain and an isogenic Nra mutant of this strain revealed the complete Nra regulon profile. Nra is active in all growth phases tested, with the largest regulon in the transition phase. Almost exclusively, virulence factor-encoding genes are repressed by Nra; these genes include the GAS pilus operon, the capsule synthesis operon, the cytolysin-mediated translocation system genes, all Mga region core virulence genes, and genes encoding other regulators, like the Ihk/Irr system, Rgg, and two additional RofA-like protein family regulators. Surprisingly, our experiments revealed that Nra additionally acts as a positive regulator, mostly for genes encoding proteins and enzymes with metabolic functions. Epidemiological investigations revealed strong genetic linkage of one particular Nra-repressed regulator, Ralp3 (SPy0735), with a gene encoding Epf (extracellular protein factor from Streptococcus suis). In a serotype-specific fashion, this ralp3 epf gene block is integrated, most likely via transposition, into the eno sagA virulence gene block, which is present in all GAS serotypes. In GAS serotypes M1, M4, M12, M28, and M49 this novel discrete genetic region is therefore designated the eno ralp3 epf sagA (ERES) pathogenicity region. Functional experiments showed that Epf is a novel GAS plasminogen-binding protein and revealed that Ralp3 activity counteracts Nra and MsmR regulatory activity. In addition to the Mga and FCT regions, the ERES region is the third discrete chromosomal pathogenicity region. All of these regions are transcriptionally linked, adding another level of complexity to the known

  8. The Streptococcus pyogenes serotype M49 Nra-Ralp3 transcriptional regulatory network and its control of virulence factor expression from the novel eno ralp3 epf sagA pathogenicity region.

    Science.gov (United States)

    Kreikemeyer, Bernd; Nakata, Masanobu; Köller, Thomas; Hildisch, Hendrikje; Kourakos, Vassilios; Standar, Kerstin; Kawabata, Shigetada; Glocker, Michael O; Podbielski, Andreas

    2007-12-01

    Many Streptococcus pyogenes (group A streptococcus [GAS]) virulence factor- and transcriptional regulator-encoding genes cluster together in discrete genomic regions. Nra is a central regulator of the FCT region. Previous studies exclusively described Nra as a transcriptional repressor of adhesin and toxin genes. Here transcriptome and proteome analysis of a serotype M49 GAS strain and an isogenic Nra mutant of this strain revealed the complete Nra regulon profile. Nra is active in all growth phases tested, with the largest regulon in the transition phase. Almost exclusively, virulence factor-encoding genes are repressed by Nra; these genes include the GAS pilus operon, the capsule synthesis operon, the cytolysin-mediated translocation system genes, all Mga region core virulence genes, and genes encoding other regulators, like the Ihk/Irr system, Rgg, and two additional RofA-like protein family regulators. Surprisingly, our experiments revealed that Nra additionally acts as a positive regulator, mostly for genes encoding proteins and enzymes with metabolic functions. Epidemiological investigations revealed strong genetic linkage of one particular Nra-repressed regulator, Ralp3 (SPy0735), with a gene encoding Epf (extracellular protein factor from Streptococcus suis). In a serotype-specific fashion, this ralp3 epf gene block is integrated, most likely via transposition, into the eno sagA virulence gene block, which is present in all GAS serotypes. In GAS serotypes M1, M4, M12, M28, and M49 this novel discrete genetic region is therefore designated the eno ralp3 epf sagA (ERES) pathogenicity region. Functional experiments showed that Epf is a novel GAS plasminogen-binding protein and revealed that Ralp3 activity counteracts Nra and MsmR regulatory activity. In addition to the Mga and FCT regions, the ERES region is the third discrete chromosomal pathogenicity region. All of these regions are transcriptionally linked, adding another level of complexity to the known

  9. A multilevel prediction of physiological response to challenge: Interactions among child maltreatment, neighborhood crime, endothelial nitric oxide synthase gene (eNOS), and GABA(A) receptor subunit alpha-6 gene (GABRA6).

    Science.gov (United States)

    Lynch, Michael; Manly, Jody Todd; Cicchetti, Dante

    2015-11-01

    Physiological response to stress has been linked to a variety of healthy and pathological conditions. The current study conducted a multilevel examination of interactions among environmental toxins (i.e., neighborhood crime and child maltreatment) and specific genetic polymorphisms of the endothelial nitric oxide synthase gene (eNOS) and GABA(A) receptor subunit alpha-6 gene (GABRA6). One hundred eighty-six children were recruited at age 4. The presence or absence of child maltreatment as well as the amount of crime that occurred in their neighborhood during the previous year were determined at that time. At age 9, the children were brought to the lab, where their physiological response to a cognitive challenge (i.e., change in the amplitude of the respiratory sinus arrhythmia) was assessed and DNA samples were collected for subsequent genotyping. The results confirmed that complex Gene × Gene, Environment × Environment, and Gene × Environment interactions were associated with different patterns of respiratory sinus arrhythmia reactivity. The implications for future research and evidence-based intervention are discussed.

  10. Factors responsible for subclinical mastitis in cows caused by Staphylococcus chromogenes and its susceptibility to antibiotics based on bap, fnbA, eno, mecA, tetK, and ermA genes.

    Science.gov (United States)

    Bochniarz, M; Adaszek, Ł; Dzięgiel, B; Nowaczek, A; Wawron, W; Dąbrowski, R; Szczubiał, M; Winiarczyk, S

    2016-12-01

    The aim of this study was to recognize selected factors of virulence determining the adhesion of Staphylococcus chromogenes to cows' udder tissues in subclinical mastitis and to evaluate the susceptibility of this pathogen to antibiotics. The subjects of the study were 38 isolates of Staph. chromogenes from 335 samples of milk from cows with subclinical coagulase-negative staphylococci mastitis. Somatic cell count ranged between 216,000 and 568,000/mL of milk (average 356,000/mL of milk). We confirmed the ability to produce slime in 24 isolates (63.2%), and the ability to produce protease in 29 isolates (76.3%). In each slime-producing isolate, the bap gene was not found, and the fnbA and eno genes were not detected. In vitro tests showed that ceftiofur had the highest effectiveness against Staph. chromogenes (89.5% of susceptible isolates). Minimum inhibitory concentrations ranged from 0.06 to 2µg/mL for susceptible isolates. The minimum concentrations required to inhibit growth of 90 and 50% of the isolates for ceftiofur were at or below the cutoffs recommended by the Clinical and Laboratory Standards Institute (2 and 0.06µg/mL, respectively). A significant percentage of the isolates were susceptible to other β-lactam antibiotics: amoxicillin with clavulanic acid (84.2%) and ampicillin (81.6%). The lowest effectiveness among β-lactams was for penicillin (73.7% of susceptible isolates), and the minimum inhibitory concentration for penicillin ranged from chromogenes (71.1 and 63.2% of susceptible isolates, respectively). The genes tetK (6 isolates) and ermA (1 isolate) were also detected. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  11. Reincarnation platn of globe. Chikyu saisei keikaku ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Matsuyama, T. (Agency of Natural Resources and Energy, Tokyo (Japan))

    1990-11-30

    The period of 200 years since the Industrial Revolution has taken for the occurence of global warming up problem, and it may require to face the problem comprehensively and for long period of 100 years unit to resolve it. This reincarnation plan of globe aims to reincarnate the changed global environment hereafter by using time of about 100 years, and proposes to make the comprehensive and long term actions to suppress and reduce exhaust gases resulting the greenhouse effect by the cooperation of all nations in the world. In the former 50 years, feasible countermeasures such as deepenung of scientific knowkedges, promotion of worldwide energy saving, introduction of clean energy, development of revolutional environmental technology, expansion of CO {sub 2} absorbing sources, and technological development of energy for the next generation will be executed continuously. In the latter 50 years, the gas exhausting amount resulting the green house effect will be reduced and suppressed from these results. Owing to these measures, the reduction of gas resulting the greenhouse effect which exceeds the expectation, can clean the globe after 100 years because the cleaning results will be incorporated into the natural circulation and the green globe will be reincarnated. 1 fig., 1 tab

  12. El cuento americano: Güeno-mapu

    Directory of Open Access Journals (Sweden)

    Gabriel Carvajal

    1966-02-01

    Full Text Available Helechos. Susurran como el abanico del pavo real. Ahí están. En grupos o hileras sobre la huella rojiza que va al caserío. Junto a la selva. Lejos, adentro, a donde solo llegan a ramonear los vahuales. En la traba de pellines, ulmos y araucarias, rosal silvestre y zarza levantada en altura de lianas y cañaveral.

  13. FY 1975 Report on results of Sunshine Project. Development of techniques of digging high-temperature beds (Conceptual designs of automatic digging systems); 1975 nendo koon chiso kussaku gijutsu no kaihatsu seika hokokusho. Jido kussaku system no gainen sekkei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-03-31

    This project is aimed at development of automatic rotary table type digging apparatus capable of digging high-temperature beds of 3,000 to 5,000 m in depth, 400 degrees C and 500 kg/cm{sup 2}. The automatic excavation apparatus is designed based on the concept that the driller is separated from the running drawworks side for other works. However, it is operated manually in a traditional manner, when the bed for which it is to be used is under complex conditions, or when the bed properties require frequent changes in digging conditions with respect to bit load and speed of rotation. The apparatus works, when the bed is considered to be under essentially constant conditions at a fairly high depth, in such a way that a combination of bit load and speed of rotation is set by the driller, and the work line wound on the drawworks drum is let out to keep the bit load constant. It is equipped with, e.g., a controller, converter and brake operating device, detecting suspension load by the controller, when it increases, increasing speed of air motor after comparing the load with the reference level, and relaxing the brake, to keep the suspension load at the set level. When the suspension load decreases, on the other hand, the air motor is decelerated to tighten the brake. (NEDO)

  14. El niño, oscilación del sur (ENOS, con relación a la transmisión de malaria, densidad y paridad de An. albimanus y An. darlingi (diptera: culicidae en dos regiones de Colombia

    Directory of Open Access Journals (Sweden)

    Ricardo Mantilla

    2000-02-01

    Full Text Available

    Una fuerte asociación ha sido registrada entre los incrementos en la transmisiónas forzadas por el fenómeno El Niño. Entre las posibles explicaciones para esta asociación está el efecto del clima sobre la dinámica de población de vectores, por ejemplo, generando cambios en la densidad y en las tasas de sobrevivencia de la población, y en la cantidad y calidad de sitios de reproducción, como también a través de cambios en el período de incubación extrínseco del parásito dentro del vector. Con el propósito de evaluar la influencia de ENOS sobre la densidad y paridad de Anopheles albimanus y An. darlingi, y su relación con la transmisión de malaria, se realizó un estudio longitudinal en Chocó y Casanare. En cada área se seleccionaron dos localidades y se realizaron muestreos entomológicos durante una semana cada mes, desde finales de 1997 hasta 1999. Este período cubrió los eventos El Niño 1997 -1998 y La Niña 1998 - 2000. En las localidades de Chocó se observó un importante incremento en el número de casos de malaria durante el evento ENOS, asociado con la temperatura. No se observó una asociación estadísticamente significativa entre los casos de malaria y la precipitación o la humedad relativa. La relación entre el incremento de malaria durante El Niño y las variables entomológicas no fue evidente. La densidad y paridad de ambas especies de vectores fluctuaron durante el período de estudio y no se encontró una asociación significativa entre estas variables y los factores climáticos como la temperatura. La precipitación y la humedad relativa. La densidad de larvas de An. albimanus fluctuó durante el estudio, y mostró altas densidades alrededor de julio - agosto. No se observó asociación entre la densidad de larvas con la densidad de adultos o las variables climáticas. El efecto del evento ENOS sobre las poblaciones de vectores

  15. Preliminaries on core image analysis using fault drilling samples; Core image kaiseki kotohajime (danso kussaku core kaisekirei)

    Energy Technology Data Exchange (ETDEWEB)

    Miyazaki, T; Ito, H [Geological Survey of Japan, Tsukuba (Japan)

    1996-05-01

    This paper introduces examples of image data analysis on fault drilling samples. The paper describes the following matters: core samples used in the analysis are those obtained from wells drilled piercing the Nojima fault which has moved in the Hygoken-Nanbu Earthquake; the CORESCAN system made by DMT Corporation, Germany, used in acquiring the image data consists of a CCD camera, a light source and core rotation mechanism, and a personal computer, its resolution being about 5 pixels/mm in both axial and circumferential directions, and 24-bit full color; with respect to the opening fractures in core samples collected by using a constant azimuth coring, it was possible to derive values of the opening width, inclination angle, and travel from the image data by using a commercially available software for the personal computer; and comparison of this core image with the BHTV record and the hydrophone VSP record (travel and inclination obtained from the BHTV record agree well with those obtained from the core image). 4 refs., 4 figs.

  16. Composición y abundancia de artrópodos epígeos del Parque Nacional Llanos de Challe: impactos del ENOS de 1997 y efectos del hábitat pedológico Abundance and composition of epigean arthropods from Llanos de Challe National Park: impacts of ENSO-1997 and effects of the pedological habitat

    Directory of Open Access Journals (Sweden)

    JORGE CEPEDA-PIZARRO

    2005-12-01

    Full Text Available Mediante el uso de trampas de intercepción, se estudió el efecto de la precipitación y el tipo de hábitat sobre la denso-actividad del ensamble de artrópodos epígeos _en particular Tenebrionidae_ del Parque Nacional Llanos de Challe. Este parque está ubicado en el desierto costero transicional de Chile, en la III Región de Atacama. Los muestreos se realizaron durante tres días por mes (septiembre, octubre y diciembre en el período de máxima actividad biológica del sistema y en los años 1989 (año no-ENOS seco, 1997 (año ENOS intenso y 2000 (año no-ENOS húmedo. En las comparaciones se utilizaron dos sitios pedológicamente contrastantes: un hábitat dunario costero y un hábitat pedregoso interior. Se registró la presencia de 15 órdenes de Arthropoda. Los hexápodos constituyeron > 95 % del total de los especímenes capturados (9.065 individuos, siendo Collembola (36,1 % y Coleoptera (29,8 % los órdenes con mayor representatividad numérica. El número de órdenes con representantes activos varió ligeramente entre años: 13 órdenes se registraron en 1989 (44 % de precipitación bajo el promedio, 15 en 1997 (443 % sobre el promedio y 11 en 2000 (52 % sobre el promedio. El efecto del evento ENOS se reflejó claramente en la contribución numérica en la mayoría de los taxa registrados. Aunque más sutilmente, este efecto también se reflejó en la composición del ensamble de taxa dominantes y entre hábitat pedológicos, particularmente con Tenebrionidae y Formicidae. Especialmente en las dunas costeras, Tenebrionidae dominó claramente el ensamble de artrópodos epígeos, siendo Gyriosomus Guérin-Méneville el género más diverso y abundante. La dominancia de Gyriosomus plantea un conjunto de interrogantes respecto de su nivel de endemismo, diversidad y distribución de sus especies, y el papel funcional de estas en el ecosistema estudiadoBy using pitfall traps, the effects of rainfall and habitat type on the denso

  17. Research on elaboration of the action plan for the New Earth 21; `Chikyu saisei keikaku` no jisshi keikaku sakusei ni kansuru chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Elaboration of the action plan for the New Earth 21 plan proposed by Japan in Houston Summit was researched. In fiscal 1995 three types of energy supply/demand scenarios, sensitivity analysis under various conditions, and cases presupposing CO2 emission regulations or not were evaluated by analysis toward 2050 using the New Earth 21 Model (NE 21 Model). Energy-saving is important, and CO2 recovery/treatment technology is introduced according to CO2 emission regulations, while attention is focussed on biomass energy. The issue of solar and wind power generation is cost reduction. In a presupposed horizontally integrated energy system, methanol represents an important intermediate energy. As a whole, CO2 reduction can be achieved by various combinations of energy-saving, introduction of regenerative energy, and CO2 recovery/treatment technology. Case studies of the action plan were conducted by unifying the evaluation criterion on coal IGCC, photovoltaic generation and biomass. The NE 21 Model was useful for elaboration of the reduction scenarios of CO2 emission. 26 refs., 84 figs., 28 tabs.

  18. Survey of implementation plan constructed for `the New Earth 21 Project`; Chikyu saisei keikaku no jisshi keikaku sakusei ni kansuru chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    It is necessary to establish scenarios for reducing CO2 emissions and for developing CO2 emission control technologies to obtain a global consensus, using appropriate analytical models. For modification of the DNE-21 (Dynamic New Earth 21) model, it has a category designated as innovative technologies not involving CO2 emission and an optional consideration for the absorption of atmospheric CO2 by biomass. A global carbon circulation model, including vegetation in its scope, is also incorporated. Major results of the simulation are shown. When 20% reduction in CO2 emissions is required for only OECD countries after the year 2020, it has been demonstrated that CO2 concentration in the atmosphere will reach as high as about 900 ppm in 2100 due to CO2 emission by developing countries, and will not be a tolerable level. Under the condition that CO2 concentration in the atmosphere is controlled at 450 ppm in 2100, the amount of renewable source of energy from photovoltaic power generation and biomass will increase and technologies of CO2 recovery and storage will decrease. Research and development of the production of methanol from recovered CO2 will be adopted as innovative technology for CO2 measures. 69 refs., 112 figs., 79 tabs.

  19. Space tourism; next goal of rocketry; Uchu eno ryokaku yuso

    Energy Technology Data Exchange (ETDEWEB)

    Inatani, Y. [Institute of the Space and Astronautical Science,Tokyo (Japan)

    2000-01-05

    As to the space travel to be conducted as business, the paper presented the results of the study being made to extract subjects. The single-stage space transport system which can be completely reused is said to be realized by much more weight reduction in airframe structure and improvement of propulsion performance, judging from the present technology standard. The reason the present form of rocket has to be reformed is that the cost needed to put a load of 1kg into orbit around the earth is higher in order of 1 million yen than those of other vehicles. Because the rocket is disposable, it is difficult to make an enormous cost reduction, and therefore, it is necessary to realize the same operation form as that adopted to airplane. The price of tickets for space travel rationally determined by the demand side is between 1.5-2.0 million yen. The annual sales are estimated at approximately 1.3 trillion yen on the market. When calculating this as business, it is necessary to reduce the transportation cost from 1,000,000 yen to 90,000-10,000 yen. A conceptual design was made of a space travel standard airframe 'Kanko-maru.' (NEDO)

  20. Meedikud loodavad rahumeelsele leppele / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Tervishoiutöötajate kutseliitude esindajad võtsid väljakuulutatud streigihoiatuse maha lootuses, et kokkulepe meditsiinitöötajate miinimumtunnitasu osas võib sõlmida rahulikul teel. Arvamust avaldab Haiglate Liidu juhatuse esimees Urmas Sule

  1. President istutas Torisse tamme / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    President Toomas Hendrik Ilves osales Toris Eesti sõjameeste mälestuskirikus traditsioonilisel vabadusvõitluse mälestusele pühendatud jumalateenistusel ja istutas kiriku kõrvale prominentide parki tamme. Varem on sellesse parki tammepuu istutanud president Arnold Rüütel, 20. augusti klubi, endine kaitseväe juhataja Aleksander Einseln ja peapiiskop Andres Põder

  2. President Ilves kohtus õpilaste ja kaitseliitlastega / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    President Toomas Hendrik Ilves külastas mitteametlikul visiidil 9.11.2007 Pärnu Sütevaka humanitaargümnaasiumi ja Kaitseliidu Pärnumaa malevat. Sütevaka humanitaargümnaasiumis kuulas president muusikakanali MTV Europe parima uustulnuka auhinna võitnud poistebändi Bedwetters esinemist ning osales lõpuklassi ühiskonnaõpetuse tunnis, rääkides kooli loosungist "Vabadus, loovus, vastutus" inspireeritult vabadusest ja vastutusest

  3. Feminismo e/no pós-colonialismo

    Directory of Open Access Journals (Sweden)

    Deepika Bahri

    2013-11-01

    Full Text Available http://dx.doi.org/10.1590/S0104-026X2013000200018 Neste artigo, a autora discorre sobre a relação entre feminismo e pós-colonialismoa partir dos conceitos-chave nos estudos pós-coloniais, salientando as premissas, os métodose as tensões dessa aliança, bem como os desafios entre os feminismos “ocidental” e “póscolonial”no contexto da globalização.

  4. Research and development project plans for FY 1995; 1995 nendo kenkyu kaihatsu jigyo keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The present research and development project plans for FY 1995 administrated by NEDO consist of research and development of new energy, and research and development of industrial technology. Are illustrated further enhancement of new energy introduction promotion measures, new stage of international projects, promotion of new energy and new energy technology development, further enhancement of industrial and scientific technology research and development, integrated measures against global and urban environment problems, and budget of NEDO projects in FY 1995. The research and development of new energy includes coal conversion technology, solar energy technology, geothermal energy technology, energy conversion and storage technology, hydrogen, alcohol and biomass energy technology, geothermal energy resources, coal resources development, new energy promotion department activities, NEDO information center activities, and so on. On the other hand, the research and development of industrial technology includes research and development of industrial technology, and global environment technology. The research and development of industrial technology consists of superconductivity, new materials, biotechnology, electronics, information and communications, machinery and aerospace, natural resources, humanity, life and society, and various leading researches.

  5. Revised design calculations of lift systems; Elevator no setsubi keikaku ni okeru kotsu keisan

    Energy Technology Data Exchange (ETDEWEB)

    Maeda, T.; Komaya, K. [Mitsubishi Electric Corp., Tokyo (Japan)

    1998-07-01

    For sufficient transportation capacity and passengers comfort and convenience, it is very important to design the suitable lift systems (e.g., the appropriate number of cages, velocity, capacity etc.) using a model which describes real elevator movements. The procedure used in conventional design calculations for office buildings is to determine the transportation capacity for the up-peak traffic situation using a simple passengers arrival model. This paper presents a new design calculations using balanced traffic model, which can deal with the elevator movements considering passengers arrival rate. As some performance indexes to evaluate the quality of service can be calculated by using this model, lift system designers can determine the appropriate lift facilities as to satisfy their goals. The validity of the proposed model is also shown by comparing with the measured data in real lift systems. 6 refs., 9 figs., 2 tabs.

  6. Indices for planning wind power generation; Furyoku hatsuden no keikaku shihyo

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, H

    1997-11-25

    Outlined herein are status of wind power generation development, indices for planning development, and actual development results. At present, wind power generates electric power of 6,781MW worldwide. USA has been rapidly developing wind power generation since enactment of the PURPA law, and accounted for 25% of the world output in the past. However, the county is recently unseated from the world top position by Germany, which has been extensively developing wind power generation since enactment of the EFL law to reach 1,799MW. In Japan, electric power companies, local governments and public institutions have been positively introducing wind mills since 1992, when Tohoku Electric Power Co. built Ryuhi Wind Park, now generating a total power of 15MW by 64 units located at 33 different points. According to the surveys by NEDO on wind conditions, there are a number of districts suited for wind mills in Hokkaido, Tohoku, Okinawa and sea areas in Honshu. The indices described herein for planning wind power generation include rotor diameter, tower height, speed of rotation, weight, power to be generated, utilization and service factors, noise level, and investment and running costs. In the present state of the development of wind power generation in Japan, development points are 33, generated ouptut 15,097kW and units 64. 14 figs.

  7. Programs for promoting new energy introduction into Wakkanai City; Wakkanaishi shin energy donyu sokushin keikaku keikakusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The average temperature in the summer season at Wakkanai is 19 degrees C, and below zero degrees C in the winter season. Solar radiation duration is shorter in November through February due partly to the presence of snow. In terms of total solar radiation amount, the city occupies a middling position in the whole Hokkaido island. As for the force of the wind, a daily maximum wind velocity of 10m/s or stronger occur on 8 to 10 days every month in the period October through May. As projects for promoting new energy introduction, the below-named ones are chosen and subjected to examination for feasibility. They are a wind power generation system for a water purification plant; a district heating system utilizing cogeneration at the city middle sector; a hybrid system of methane fermentation and wind power generation for a public stock-rearing farm; a hybrid system of cogeneration and photovoltaic power generation for Fujimi district accommodation facilities; and photovoltaic power generation as a clean energy introduction system for a general gymnastic hall of Wakkanai City. Since the above-named subjects are all excellent in economy and environmentally-friendliness, it is suggested that efforts be exerted to realize them. (NEDO)

  8. Planning of Tatara Bridge. Chodai shachokyo-Tataraohashi-no keikaku gaiyo

    Energy Technology Data Exchange (ETDEWEB)

    Okukawa, A. (Honshu-Shikoku Bridge Authority, Tokyo (Japan))

    1991-12-05

    The outline of the Tatara Bridge is given to introduce the features of the entire structural system and fundamental problems concerning the construction of the huge cable stayed bridge. The central span of the bridge is 890m. The topography and geological features of the bridging point are reviewed, and social conditions such as being in a national park, safety for sailing, etc. are taken into consideration for various technological studies on the construction of the huge bridge. Bridge piers are provided in the side spans and appropriate counter weight is loaded to design a more economical bridge which is more suitable for the topography as compared with a suspension bridge. The cable stayed bridge requires no anchorage which is necessary for a suspension bridge with very little topological alteration, and an excellent result is obtained both in cost and term of construction as compared with a suspension bridge. The rigidity of the cable stayed bridge is high, and the stability of the resistance to wind of the structure is also very satisfactory. As a result, it is concluded that the bridge can be designed and constructed using currently available technologies, and a cable stayed bridge is selected in August, 1990 as the type for the Tatara Bridge. 9 figs., 1 tab.

  9. Planning and design of the Ikedako bride (temporary name); Ikedakokyo (kasho) no keikaku to sekkei

    Energy Technology Data Exchange (ETDEWEB)

    Mochizuki, H.; Iizuka, Y.; Yukawa, Y. [Japan Highway Public Corporation, Tokyo (Japan)

    1997-09-30

    This paper describes the planning and design of the Ikeda-Lake Bridge of the Tokushima Express Way. This bridge is a PC (prestressed concrete) five-span continuous balanced arch bridge with a length 705 m. This bridge transverses prefectural road, Ikeda Dam Lake of Yoshino River, park, JR line, national highway, and town road, and both ends of the bridge are tunnels, resulting in the complicated bridging condition. Various bridging methods were examined from the viewpoint of structural characteristics, workability, profitability, maintenance/management, and aspect. A bridge with PC stiffening girders was adopted. The maximum interval between supports is 200 m. This bridge has the largest scale as a concrete arch bridge in Japan. Basements of bridge piers were constructed by pneumatic caisson method and large-diameter deep basement method. Since basements were located in the dam lake and they were quickly constructed in a short period in a non-flood season, steel caissons were separately fabricated in the dock, towed and placed for excavation. For the construction of upper section, overhang method was adopted using movable working vehicle. For the construction of arch section, the arch was overhung simultaneously in the both sides by composing the truss using stiffened girders, arch ribs, vertical members, and temporary cable stayed members, which was the first in Japan. In 1997, basement construction was completed, and construction of bridge piers and a part of the construction of upper section have been started. 2 refs., 12 figs.

  10. Influence of spectral solar radiation to the generating power of photovoltaic module; Taiyo denchi shutsuryoku eno taiyoko supekutoru eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Minaki, S.; Ishihara, Y.; Todaka, T.; Harada, K. [Doshisha University, Kyoto (Japan); Oshiro, T.; Nakamura, H. [Japan quality Assurance Organization, Tokyo (Japan)

    1997-11-25

    As to the influence of spectral solar radiation to generating power of solar cells, a study was conducted from the aspects of season, time zone, intensity of solar radiation, etc. In the study, spectral responsive variation correction coefficients were introduced as evaluation values expressing the influence of spectral solar radiation. For the spectral distribution, an all sky spectral pyranometer by wavelength was used, and data were used which were obtained in the measurement in experimental facilities of the solar techno center. Concerning solar cell relative spectral sensitivity values, used were relative spectral sensitivity values of monocrystal and amorphous standard solar cells to the short-circuit current. Spectral response variation correction coefficients are coefficients correcting variations in conversion efficiency of solar cells due to changes in the spectral distribution. The changes of spectral responsive variation correction coefficients were studied using data obtained during April 1994 and March 1996. As a result, it was found that the coefficients showed large changes in summer and small ones in winter and that amorphous solar cells indicate this trend conspicuously. 3 refs., 6 figs., 3 tabs.

  11. Evaluation stationariness of triaxial seismic while drilling and detection of reflected wave; Kosei kussaku ni tomonau danseiha no sanjiku kaiseki ni yoru hiteijo hyoka to hanshaha no kenshutsu

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, T; Asanuma, H; Niitsuma, H [Tohoku University, Sendai (Japan). Faculty of Engineering

    1996-05-01

    This paper reports a method to detect reflected wave components contained in an elastic wave caused in association with well drilling. Measurement was made on an elastic wave caused in association with well drilling in an experimental field by using a triaxial elastic wave detector disposed in a measurement well. Analyzing the particle motion tracks in the derived elastic wave signals (to derive the main axial direction of a three-dimensional hologram) revealed that oscillation direction of the signals changes non-steadily by time centering around the S-wave oscillation direction. In addition, a sound source position was estimated during the drilling. Existence probability of the S-wave signal in the non-steady continuous signals was estimated by handling the particle motion tracks stochastically. In addition, this existence probability was used as a weighting function for a correlative analysis to detect a reflected wave from directly reaching wave components in the non-steady continuous signals. Thus, improvement in reliability of reflected wave detection was attempted. Effectiveness of this method was endorsed by the field data. 3 refs., 7 figs.

  12. Quiet tunneling method in hard rock mass by cutting grooves and fracturing rock; Mizo wo hori, iwa wo wari, katai tonneru wo shizukani kussaku

    Energy Technology Data Exchange (ETDEWEB)

    Noma, T. [Fujita Corp., Tokyo (Japan)

    1998-08-15

    Where blasting cannot be applied due to large vibration and noise, adoption of mechanical tunneling is essential to tunneling of hard rock. In tunneling of hard rock, the existing of free surface is important. The free surface means a surface which does not restrict destruction on fracturing and it is important to form a continuous free surface efficiently and economically. The development of a new free surface forming engineering method is described. It requires no exclusive machines and all drilling works can be operated with general drill jumbo machine. In this new engineering method, the free surface is formed by continuous drilling of a single hole. Spinning anti-bend (SAB) rod is inserted into the existing drilled hole and a drill bit generates the free surface by contact with and blow the SAB rod. The procedure of the continuous drilling, an application example and the features of the procedure are described. This method has an ability to form a free surface more than 3.5m{sup 2}h even for rock bed wit compression strength more than 200MPa. 2 refs., 8 figs.

  13. Report of the 8th International Symposium on the Observation of the Continental Crust Through Drilling; Dai 8 kai tairiku kagaku kussaku kokusai symposium ni sankashite

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, K. [Super Deep Core Drilling Study Group, Japan, Tokyo (Japan)

    1996-11-29

    This report relates to the 8th International Symposium on the Observation of the Continental Crust Through Drilling, convened at Agency of Industrial Science and Technology, Tsukuba City, on February 26, 1996. The symposium was represented by approximately 200 people from the U.S., Canada, Britain, Germany, France, Russia, China, and some others, who discussed active faults, drilling and logging, transfer of fluids and heat in the crust, history of the earth and climate, ICDP (International Continental Scientific Drilling Program) and international cooperation under this program in the future, etc. In reference to ultradeep drilling in the world, drillings by Germany`s KTB (Kontinentales Tiefbohrprogramm)(9,101m deep) and Russia at Kola Peninsula (l2,261m) were reviewed. Concerning the efforts of U.S. Continental Scientific Drilling Program during the previous 11-year period, it was reported that it had cost a total of $84,000,000; that investigations had been made into volcanos and geotherm, fault tectonics, sedimentary basins, holes due to meteorites, and metal ore deposits; and that 61 holes (total length: 31,310m and maximum depth: 3,510m) had been drilled and investigated. 6 figs., 3 tabs.

  14. Selecting, engineering and constructing drilling sites at the Geysers geothermal field. Geysers chinetsu ryoiki ni okeru kussaku shikichi no sentei engineering kochiku

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    This paper describes some examples of selection, engineering and construction of drilling sites at the Geysers geothermal field in the northern district of California State. Steep landform, thin-layered soil and violent rainfall create unstable conditions bringing about numerous landslide in the field. Selection of a well drilling site appropriate in such conditions is started by analyzing the aerial photographs by technical staff. After site selection, prospecting and soil test are conducted and a working plan in the well site is decided to prepare engineering drawings. In the construction, land preparation, the open-cutting of base-line trench, etc. are carried out. The base-line trench is a large and sufficiently deep one which is open-cut to the front end or the middle of the bottom part of the well plateau. The final construction work is to build a leading casing for interpolating cementing. The well site construction in the Geysers geothermal field is done in consideration of protecting human life, health and properties. 1 fig.

  15. FY 1974 Report on results of Sunshine Project. Feasibility study on digging high-temperature beds; 1974 nendo koon chiso kussaku ni kansuru feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1975-03-31

    The desired target geothermal conditions for which the digging equipment is to be developed are 3,000 to 5,000 m as depth, 400 degrees C as temperature and 500 kg/cm{sup 2} as pressure. As the first phase, the study is conducted on feasibility of development of techniques for digging high-temperature beds under a temperature condition of 250 degrees C, where the rotary table type digger is mainly studied. It is most widely used for digging oil wells as well as geothermal wells. The current rotary table B type digger is studied as the equipment serviceable at 250 degrees C as the target temperature level for the moment for digging high-temperature beds. The studied items include the problems involved in the digger body, pipes, bits and other members, and also measures to expand its possibility. Also studied/surveyed are applicability of the new digging techniques now under development to geothermal wells, and techniques for fracturing high-temperature rocks. This report summarizes to help select the methods desired to be developed in the future, and plan development of the digging systems. (NEDO)

  16. Fiscal 1997 survey report. Survey on the innovative well drilling technology; 1997 nendo chosa hokokusho. Kakushinteki kosei kussaku gijutsu ni kansuru chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In the geothermal drilling, reduction of the cost of well drilling is an important subject for technical development. The geothermal resource development tends to be made at higher temperatures and at deeper wells. In the present drilling technology, the cost is rising with the exponentially increasing depth and temperature, and there is also occurring the technical limit. Accordingly, the survey clarified the limit of the present drilling technology/cost to point out the research trend of the drilling technology as substitute for the present one, possibilities of the introduction, and the R and D target and subjects. As to latest drilling systems abroad and in Japan, the following were surveyed to study and extract promising technologies and systems: improvement/application of drilling equipment/materials (enhancement of heat resistance of the main drilling equipment, etc., cooling effects of top drive, heat resistance verification of MWD tools, PDM, tricone bits, multi-stage cementing tools, etc.), heightening of drilling rates, trend surveys of slim hole drilling, control drilling, well maintenance/workover, and well design technology. 68 refs., 73 figs., 40 tabs.

  17. FY 1975 Report on results of Sunshine Project. Development of techniques of digging high-temperature beds (Feasibility study on digging high-temperature beds); 1975 nendo koon chiso kussaku gijutsu no kaihatsu seika hokokusho. Koon chiso kussaku ni kansuru feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-03-31

    The environmental conditions for which the digging techniques are to be developed have been set at 3,000 to 5,000 m as depth, 400 degrees C as temperature and 500 kg/cm{sup 2} as pressure. The environmental temperature was set at 250 degrees C as the first phase in the previous year. In this year, the temperature level is increased to 400 degrees C for the feasibility study on technological development. For development of the high-temperature bed digging apparatuses, masts, sub-structures, drawworks, slurry pumps, and pipe addition handling are studied as the problems involved in the rotary table method. Also studied are the related themes, e.g., drill pipes, drill collars, casing pipes, slurry, cementing and instruments to be installed in geothermal wells. For development of the bits, various problems to be solved are studied, including slurry circulation systems, bit diameter and speed of rotation, and bit configurations as those involved in the digging systems; heat-resistant materials, bit tooth forms, hardening of the edges, bearing configurations and cooling mechanisms as those involved in the bit structures; and optimum service conditions and selective use standards for roller cutter and solid bits. Other items studied include structures of the apparatuses for geothermal well mouth, and wear of digging tools for the air drilling method. (NEDO)

  18. Report on achievements in fiscal 1979 in Sunshine Project. Development of a high-temperature ground layer drilling technology (feasibility study on high-temperature ground layer drilling); 1979 nendo koon chiso kussaku gijutsu no kaihatsu seika hokokusho. Koon chiso kussaku ni kansuru feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-03-01

    This paper reports research achievements on the following items: (1) a roller cutter bit, (2) solid bit and air friction bit, and (3) bit materials. In Item 1, fabrication and test were performed on a roller cutter bit on which studies were made for use, heat treatment, and manufacturing method of improved heat resistant steels. Effects were obtained in tip retention force when high-temperature rocks are drilled. Research and development was made on construction of a bearing as a friction type bit, in which dry bearing pressed in with a solid lubricating agent was inserted into an outer race. In Item 2, an indoor drilling test was carried out on a solid bit using two-layered ultra hard tip. A durability test on an air friction bit bearing recognized no wear on a check after operation of about 40 hours under a load of 3 tons and at a rotation speed of 80 rpm. Thus, the bearing was considered sufficiently reliable from the aspect of durability. In mud water drilling in the field, some wear was observed in the thrust direction. In Item 3, studies were performed on heat and corrosion resistant tip materials, bit materials using heat resistant alloys, improvement in bearing materials, strengthening of inside of a cutter made of metallurgically sintered powder, provision of heat resistance onto bit materials, indoor cutting tests, and seals for bits. (NEDO)

  19. FY 2000 report on the results of the survey of the project for implementation of 'The New Earth 21'; 2000 nendo 'chikyu saisei keikaku' no jisshi keikaku sakusei ni kansuru chosa jigyo hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    As the research study contributing to implementation of 'The New Earth 21' proposed by Japan at the Houston Summit in 1990, a DNE21 model was developed as a quantitative assessment model for global warming preventive technology, heightening of efficiency of the global energy supply/demand system, conversion to energy sources of low carbon emissions, etc. In the project of 'The New Earth 21,' economy and environment can be compatible centering on developed countries' technical development and technology transfer to developing countries. In FY 2000, for heightening applicability of the DNE21 model, the world, which was used to be divided into 10 regions, was divided into 54. At the same time, a prototype model was constructed in which cities in the region were divided into three cities: large; medium; small. Using the DNE21 model, evaluation was made of effects of uncertainties such as population, economic growth, final energy demand and cost as preconditions of the model on the optimization of global warming preventive measures. Further, technologies which are expected to be important for global environmental policy in the ultra-long term were listed up to estimate the potentiality. (NEDO)

  20. Fiscal 1997 report on the survey project on planning to execute `The New Earth 21`; 1997 nendo chosa hokokusho (`chikyu saisei keikaku` no jisshi keikaku sakusei ni kansuru chosa jigyo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Japan proposed in the Houston Summit the New Earth 21 to be carried out with technology development and technology transfer, and to make a concrete development of the project, Japan also proposed in the Tokyo Summit a TREE Plan for working out comprehensive strategies of the innovative technology development. In the CO3 Kyoto Conference in 1997, numerical targets for developed countries were determined which have legal binding force for control/reduction of greenhouse gas emissions in the term of 2008-2012. It was agreed to urge developing countries also to play a certain part in the project through the clean development. Therefore, the paper made quantitative analysis of important CO2 prevention technologies, technology transfer costs, and economical assessment by energy conservation. As a model, the DNE 21 model was upgraded and used into which CO2 prevention technologies, energy, economy and climate changes were integrated. In fiscal 1997, the following were carried out: collection of data on important CO2 prevention technologies and systems and analytical assessment using the DNE 21 model, CO2 reduction and selection of energy technology, assessment of energy system costs, construction of the unified DNE 21 model, and opening of the international workshop. 62 refs., 98 figs., 34 tabs.

  1. Research report for fiscal 1998. Research for 'New Earth 21' project implementation program preparation; 1998 nendo chosa hokokusho. 'Chikyu saisei keikaku' no jisshi keikaku sakusei ni kansuru chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For the establishment of a CO2 measures introduction scenario which the world would accept, the latest information was collected, the DNE21 (Dynamic New Earth 21) model was improved, and simulation was reviewed. In fiscal 1998, simulation was performed for each district using an LDNE21 (Linear Dynamic New Earth 21) model, and an energy flow chart, energy balance table, and trade table were prepared and subjected to detailed deliberation. Studied were also conducted about the changes to occur in methanol production when the natural gas reserves and plant cost data were given different values. In the DNE21 model, the 'macro economy model' and 'warming damage function' were integrated, and simulation was performed for verification. Using a standard model compatible with COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change), comparison was made between a case in which different CO2 emission constraints were imposed on the advanced area and developing area separately and a case in which one and the same constraint was imposed on the world as a whole, and calculations were made about CDM (Clean Development Mechanism). (NEDO)

  2. Research report for fiscal 1998. Research for 'New Earth 21' project implementation program preparation; 1998 nendo chosa hokokusho. 'Chikyu saisei keikaku' no jisshi keikaku sakusei ni kansuru chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For the establishment of a CO2 measures introduction scenario which the world would accept, the latest information was collected, the DNE21 (Dynamic New Earth 21) model was improved, and simulation was reviewed. In fiscal 1998, simulation was performed for each district using an LDNE21 (Linear Dynamic New Earth 21) model, and an energy flow chart, energy balance table, and trade table were prepared and subjected to detailed deliberation. Studied were also conducted about the changes to occur in methanol production when the natural gas reserves and plant cost data were given different values. In the DNE21 model, the 'macro economy model' and 'warming damage function' were integrated, and simulation was performed for verification. Using a standard model compatible with COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change), comparison was made between a case in which different CO2 emission constraints were imposed on the advanced area and developing area separately and a case in which one and the same constraint was imposed on the world as a whole, and calculations were made about CDM (Clean Development Mechanism). (NEDO)

  3. Fiscal 1999 survey report. Study project concerning preparation for implementation plan of 'the new earth program'; 1999 nendo 'chikyu saisei keikaku' no jisshi keikaku sakusei ni kansuru chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This paper reports fiscal 1999 survey of the new earth program. Toward the target of GHG (green house effect gasses) 550 ppm, sensitivity analysis using a linear DNE21 model was replenished, with model analyses made on a scenario concerning the countermeasure technologies/systems. In other words, performed were the improvement of accuracy by the renewal of data, sensitivity analysis concerning CO2 collection/processing technology and nuclear energy, analysis of the international regulation for controlling CO2 concentration under 550 ppm in the air in the year 2100, and sensitivity analysis on increase in per capita energy demand in Asia. Overall assessment of global warming problems was upgraded for the purpose of enabling the assessment from the consumption maximization point of view, taking into consideration cooling effects of SOx and economic growth. Potentiality assessment in rational use of energy was reexamined because energy conservation played an important role. That is, in DNE model, the data were examined of OECD signatories and developing countries from 1970s concerning natural gas, petroleum, coal and electric power, with the long-term cost flexible value estimated. In addition, feasibility was assessed of rational use of energy from energy GNP unit. (NEDO)

  4. Status of the superconductive Maglev program in the United States; Amerika ni okeru chodendo jiki fujo tetsudo keikaku no genjo

    Energy Technology Data Exchange (ETDEWEB)

    Osaki, H [Tokyo Univ. (Japan). Faculty of Engineering

    1994-07-25

    In the United States, high speed transportation plan was approved in 1965, and research and development of the superconductive magnetically levitated system (Maglev) became active. Although research and development for design, construction, and test for 500km/h Maglev were started in 1974, the federal government ordered to stop in 1975 all the development projects of high speed transportation traffic systems, and the activity slowed down very much as compared with those in Japan, Germany, and other countries. In 1990, the National Maglev Initiative (NMI) project was established. The feature which is different from those of Japanese and German systems is 0.16g and larger acceleration, which allows to shorten the transit time between stations. Development plan for Maglev prototype was approved officially in November, 1991. Features of levitation, guidance, propulsion as well as the carriage lineup of the 4 systems conceptually designed in the NMI project are introduced. 22 refs., 4 figs., 57 tabs.

  5. Practical method for generation expansion planning based on the dynamic programming. Dynamic programming ni motozuku dengen keikaku shuho

    Energy Technology Data Exchange (ETDEWEB)

    Tanabe, R.; Yasuda, K.; Yokoyama, R. (Tokyo Metropolitan Univ., Tokyo (Japan))

    1992-05-20

    To supply cheap, high-reliable and a planty of the electricity is an important task of the electric supply system because the requirement for the electricity is rapidly increased in Japan. In order to solve this problem, the authors of the paper are developing a most suitable practical method based on algorithm, according to which the generation expansion planning is divided into two problems: the optimal generation mix and the optimal generation construction process and the two problems are solved respectively. But there are some bad points in the method, for example, there are only approximative practical restriction of the capacity of single machine and the existing electric supply etc., because the optimal generation mix is determined on the basis of non-linear planning. So, in the present paper, the electric supply support system is practically constructed while proposing an unified generation expansion planning based on the dynamic programming that is possible to consider these restrictions strictly and the usefullness of the method is inspected. 12 refs., 7 figs., 5 tabs.

  6. Achievement report for fiscal 1982 on Sunshine Program. Coal energy; 1982 nendo sunshine keikaku seika hokokusho. Sekitan energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-07-01

    This research program consists of (1) the solid catalyst-aided reforming of various petroleum based oils and heavy coal oils into Solvolysis solvents and the secondary hydrogenolysis, (2) a search for pre-treatment for improvement on the sub-bituminous coal liquefaction yield, and (3) a search for measures for improvement on the brown coal liquefaction yield. Studied in this fiscal year are (1) the high-temperature short-contact time liquefaction of brown coal, (2) the role of catalyst support for selective upgrading of SRC (solvent refined coal), and (3) reforming of thermal melting feature of low rank coal by preliminary deashing at room temperature. In relation with Item (1), it is found that the dehydrogenation or reaction to carbonization of molecules involved in hydrogen donation is structure-sensitive but that thermolysis of coal is accelerated under high-temperature conditions to allow transfer hydrogen to contribute uniformly. It is deemed also that matching is excellent between hydrogen transfer and thermolysis, that the solvent dissolution level is elevated, and that the reaction short in duration inhibits consecutive polymerization reaction. These are supposed to be effective in improving on the liquefaction yield and in rendering heavy constituents lighter. In relation with Item (2), it is found that the experimentally manufactured catalysts are effective in reducing the weight of heavy constituents. In relation with Item (3), a carbonization reforming method is experimentally implemented in which the ash that affects carbonization is further removed by a pre-treatment at room temperature. (NEDO)

  7. FY 1998 New Sunshine Project. International co-operative project (Summary); 1998 nendo new sunshine keikaku. Kokusai kyoryoku jigyo (sogoban)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Described herein are the basic plans for the international co-operative projects for development of technologies for commercialization of photovoltaic power systems (e.g., IEA co-operative programme on Photovoltaic Power Systems), and the minutes of the FY 1997 and 1998 meetings of the Solar Energy Technology International Research Co-operative Committee. Japan is responsible for implementing the following projects for promoting international cooperation for, e.g., IEA Photovoltaic Power Systems (PVPS): research and development, demonstration, analysis, information exchange, introduction promotion, etc. for IEA/PVPS Programme; and research and development, demonstration, analysis, information exchange, introduction promotion, etc. for IEA/Solar Heating and Cooling Programme. Japan is also implementing the co-operative projects for the photovoltaic power systems with the Summit participants, based on Science and Technology Working Group established by the Versailles Summit, technology cooperation with, e.g., Australia, and bilateral information exchange and technological survey projects with those countries which have already developed solar energy systems, e.g., USA, France, Spain and Italy. (NEDO)

  8. FY 1981 Report on the results of Sunshine Project. Coal energy; 1981 nendo sunshine keikaku seika hokokusho. Sekitan energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-07-01

    This report presents the results of (researches on solvolysis liquefaction mechanisms and reaction promotion with oil- and coal-based solvents), conducted as part of the research and development project for coal liquefaction techniques. The FY 1981 program includes researches on (1) the effects of liquefaction reaction conditions on liquefaction yield and production of light products for coal species of low degree of carbonization, including brown coal, (2) the effects of pretreatment of coal on its liquefaction reactivity, and (3) up-grading of the solvolysis coal liquid (SCL). For the item (1), HA240 (hydrogenated Ashland's A240) is used to investigate its liquefaction capacity for various coal species of low degree of carbonization, including brown coal. For the item (2), the effects of pretreatment in a hot water bath with reflux was investigated for sub-bituminous coal in the FY 1980. In the FY 1981, various pretreatment methods are attempted for enhancing liquefaction reactivity of brown coal. As a result, it is found that ash content of brown coal is decreased to one-third of the initial level, when it is treated in a diluted hydrochloric acid bath with reflux. For the item (3), SCL hydrogenated by Birch reduction (B-SCL, 1) is compared with H-SCL with respect to properties, structures and thermal crackability, to discuss the items required for the catalyst to be used in the second stage by clarifying effectiveness of the catalyst. (NEDO)

  9. Summary of reports on 1979 result of Sunshine Project. Solar energy; 1979 nendo sunshine keikaku seika hokokusho gaiyoshu. Taiyo energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-04-01

    This report is a compilation of all outlines of the results concerning 'solar energy' for which R and D was carried out as a part of Sunshine Project in fiscal 1979. The research subjects (items of the studies) are written below. 1. Solar energy system (measurement of spectral irradiance, utilization system, and meteorological investigation); 2. Solar thermal power generation system; 3. Photovoltaic power generation system (basic research on solar cells, silicon vertical ribbon crystal, silicon horizontal ribbon crystal, particle non-acceleration growth type thin film silicon crystal, particle acceleration growth type thin film silicon crystal, new type solar cells, secondary to quaternary compound semiconductor solar cells, and photovoltaic power generation system); 4. Solar cooling, heating and hot water supply system (evaluation system, newly-built private residential system, existing private residential system, multiple dwelling system, large building system, synthetic resin materials, glass based materials, and metallic materials); 5. Solar energy new utilization method (new power generation system and materials); 6. R and D on solar thermal power generation plant (R and D on pilot plant, experimental research for developing plant on curved surface converging method, and experimental research for developing plant on tower converging method). (NEDO)

  10. Summary of the FY 1988 Sunshine Project results. Hydrogen energy; 1988 nendo sunshine keikaku seika hokokusho gaiyoshu. Suiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-04-01

    Outlined herein are the results of researches on hydrogen energy as part of the FY 1988 Sunshine Project results. Researches on the techniques for producing hydrogen by electrolysis of water using a polymer electrolyte include development of power-supplying materials for electrolysis at high current density, and basic studies on the electrolysis using an OH ion conducting type polymer electrolyte. Researches on the techniques for producing hydrogen by electrolysis with hot steam include development of the materials, techniques for processing these materials, and electrolysis performance tests. Researches on the techniques for transporting hydrogen by metal hydrides include development of hydrogen-occluding alloys of high bulk density, and techniques for evaluating characteristics of metal hydrides. Researches on the techniques for storing hydrogen include those on alloy molding/processing techniques, hydrogen-storing metallic materials, and new hydrogen-storing materials. Researches on the techniques for utilizing hydrogen include those on energy conversion techniques using hydrogen-occluding alloys, and hydrogen-fueled motors. Researches on the techniques for safety-related measures include those on prevention of embrittlement of the system materials by hydrogen. (NEDO)

  11. Summary of the FY 1989 Sunshine Project results. Hydrogen energy; 1989 nendo sunshine keikaku seika hokokusho gaiyoshu. Suiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-04-01

    Outlined herein are the results of researches on hydrogen energy as part of the FY 1989 Sunshine Project results. Researches on the techniques for producing hydrogen by electrolysis of water using a polymer electrolyte include those on the SPE electrolysis at high temperature and current density, and basic studies on the electrolysis using an OH ion conducting type polymer electrolyte. Researches on the techniques for producing hydrogen by electrolysis with hot steam include development of the materials, techniques for processing these materials, and electrolysis performance tests. Researches on the techniques for transporting hydrogen by metal hydrides include development of hydrogen-occluding alloys of high bulk density, and techniques for evaluating characteristics of metal hydrides. Researches on the techniques for storing hydrogen include those on hydrogen-storing metallic materials, alloy molding/processing techniques, and new hydrogen-storing materials. Researches on the techniques for utilizing hydrogen include those on energy conversion techniques using hydrogen-occluding alloys, and hydrogen-fueled motors. Researches on the techniques for safety-related measures include those on prevention of embrittlement of the system materials by hydrogen. (NEDO)

  12. Plan to promote new energy introduction in Niigata Prefecture area; Niigataken chiiki shin energy donyu suishin keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The 'Plan to promote new energy introduction in Niigata Prefecture area' was established to leave the conditions that everybody can live with affluence and comfort in the next generation. The plan lasts for ten years until 2010. Upon identifying the district characteristics of Niigata Prefecture, and based on the results of investigations on new energy existence quantity, utilization possibility thereof, and consciousness of residents of the prefecture, considerations were given that the plan shows the basic policy to promote proliferation of the new energies, and serves as the guideline for practical implementation. The plan document is composed of the following four items: 1) the foreword, 2) the current status of energies, 3) new energies expected of introduction, and 4) basic measures. The energy consumption was estimated to increase to 1.345 times that of fiscal 1990 in the year 2010, the increase being mainly in consumer and household use. The targeted quantity for new energy introduction was set to 90,000 kl annually as converted to petroleum. Expected new energy applications would include photovoltaic power generation, snow energy and solar heat utilization, and cogeneration utilizing natural gas. (NEDO)

  13. Risk communication. Risk studies in social science; Risk communication. Risk kenkyu eno shakai kagakuteki approach

    Energy Technology Data Exchange (ETDEWEB)

    Asami, M. [Keio Univ., Tokyo (Japan)

    1995-11-05

    It is recently, that is, in and after the 1980s that socio-scientific approaches began to be made to studies on `risk`. It started to be made clear that the progress of the scientific technology does not necessarily bring about good news to man, and obvious estrangement has begun to appear between scientific evaluation and social evaluation of risk. The subject of risk communication (RC) study is to tackle a proposition whether the estrangement will continue to exist as estrangement or the estrangement can be made smaller by any means. This paper explains the recent trend of the study. For example, as for how each individual thinks about risk, that is, the risk perception, a new framework is trially being constructed by introduction of the quantitative method using psychometrics. A duty of RC is to serve to bridge the gap between scientific technology and society which are controlled by values which are incompatible with each other. Therefore, RC will be more and more important. 15 refs., 1 fig., 2 tabs.

  14. Application of wavelet transform to seismic data; Wavelet henkan no jishin tansa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Nakagami, K; Murayama, R; Matsuoka, T [Japan National Oil Corp., Tokyo (Japan)

    1996-05-01

    Introduced herein is the use of the wavelet transform in the field of seismic exploration. Among applications so far made, there are signal filtering, break point detection, data compression, and the solution of finite differential equations in the wavelet domain. In the field of data compression in particular, some examples of practical application have been introduced already. In seismic exploration, it is expected that the wavelet transform will separate signals and noises in data in a way different from the Fourier transform. The continuous wavelet transform displays time change in frequency easy to read, but is not suitable for the analysis and processing large quantities of data. On the other hand, the discrete wavelet transform, being an orthogonal transform, can handle large quantities of data. As compared with the conventional Fourier transform that handles only the frequency domain, the wavelet transform handles the time domain as well as the frequency domain, and therefore is more convenient in handling unsteady signals. 9 ref., 8 figs.

  15. Spatial autocorrelation method using AR model; Kukan jiko sokanho eno AR model no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Obuchi, T; Saito, T [Iwate University, Iwate (Japan). Faculty of Engineering

    1996-05-01

    Examination was made about the applicability of the AR model to the spatial autocorrelation (SAC) method, which analyzes the surface wave phase velocity in a microtremor, for the estimation of the underground structure. In this examination, microtremor data recorded in Morioka City, Iwate Prefecture, was used. In the SAC method, a spatial autocorrelation function with the frequency as a variable is determined from microtremor data observed by circular arrays. Then, the Bessel function is adapted to the spatial autocorrelation coefficient with the distance between seismographs as a variable for the determination of the phase velocity. The result of the AR model application in this study and the results of the conventional BPF and FFT method were compared. It was then found that the phase velocities obtained by the BPF and FFT methods were more dispersed than the same obtained by the AR model. The dispersion in the BPF method is attributed to the bandwidth used in the band-pass filter and, in the FFT method, to the impact of the bandwidth on the smoothing of the cross spectrum. 2 refs., 7 figs.

  16. Water supply method to the fuel cell cooling water system; Nenryo denchi reikyakusuikei eno kyusui hoho

    Energy Technology Data Exchange (ETDEWEB)

    Urata, T. [Tokyo (Japan); Nishida, S. [Tokyo (Japan)

    1996-12-17

    The conventional fuel cell has long cooling water piping ranging from the fuel cell exit to the steam separator; in addition, the supply water is cooler than the cooling water. When the amount of supply water increases, the temperature of the cooling water is lowered, and the pressure fluctuation in the steam separator becomes larger. This invention relates to the water supply method of opening the supply water valve and supplying water from the supply water system to the cooling water system in accordance with the signal of the level sensor of the steam separator, wherein opening and closing of the supply valve are repeated during water supply. According to the method the pressure drop in every water supply becomes negligibly small; therefore, the pressure fluctuation of the cooling water system can be made small. The interval of the supply water valve from opening to closing is preferably from 3 seconds to 2 minutes. The method is effective when equipment for recovering heat from the cooling water is installed in the downstream pipeline of the fuel cell. 2 figs.

  17. Sorption mechanism of solvent vapors to coals; Sekitan eno yobai joki no shuchaku kiko no kaiseki

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, K.; Takanohashi, T.; Iino, M. [Tohoku University, Sendai (Japan). Institute for Chemical Reaction Science

    1996-10-28

    With an objective to clarify the interactions between micropore structure of coal and solvent reagents, a sorption experiment was carried out under solvent saturated vapor pressure. Low-volatile bituminous coal, Pocahontas No. 3 coal, has the aromatic ring structure developed, and makes solvent more difficult to diffuse into coal, hence sorption amount is small. Methanol has permeated since its polarity is high. High-volatile bituminous coal, Illinois No. 6 coal, makes solvent penetrate easily, and the sorption amount was large with both of aromatic and polar solvents. Since brown coal, Beulah Zap coal, contains a large amount of oxygen, and hydrogen bonding is predominant, sorption amount of cyclohexane and benzene having no polarity is small. Methanol diffuses while releasing hydrogen bond due to its polarity, and its sorption amount is large. A double sorption model is available, which expresses the whole sorption amount as a sum of physical sorption amount and amount of permeation into coal. This model was applied when it explained successfully the sorption behavior of the solvents relative to coals, excepting some of the systems. However, also observed were such abnormal behavior as sorption impediment due to interactions between coal surface and solvents, and permeation impediment due to hydroxyl groups inside the coals. 1 ref., 10 figs., 2 tabs.

  18. Adjustment of muscle function to flight in bats; Komori no kinkino no hiko eno tekio

    Energy Technology Data Exchange (ETDEWEB)

    Yamashita, M. [Institute of the Space and Astronautical Science,Tokyo (Japan); Choi, I.H.

    1999-12-05

    This paper outlines the muscle of bats that generates a motive force for flight. The weight of the muscle is less compared with that of birds. The energy required for flight is twice as much as that for running. Conversely, in view of metabolic cost (transporting cost) for moving a unit mass for a unit distance, the transporting cost of bats for flying is one fifth. The acquisition of this flight ability through evolution can be inferred from the fossils of reptiles. Bats, having a stream-lined body shape and a small body mass, are capable of efficient flight. A fast durable flight is possible by having the pectoral muscle constituted of speed muscles of oxidation/glycolysis muscle fiber, a well-developed oxygen transporting system, the arrangement around the capillary of mitochondria and fat grains that are cell organs for producing energy, and a high-density contact between the capillary and the muscle fiber. The muscle functions at low body temperature and imparts adaptability to hibernation with the body temperature lowered. The flight is controlled by the cycle and synchronized with this biological clock, optical cycle and change in temperature. (NEDO)

  19. Resting Tension Affects eNOS Activity in a Calcium-Dependent Way in Airways

    Directory of Open Access Journals (Sweden)

    Paschalis-Adam Molyvdas

    2007-03-01

    Full Text Available The alteration of resting tension (RT from 0.5 g to 2.5 g increased significantly airway smooth muscle contractions induced by acetylcholine (ACh in rabbit trachea. The decrease in extracellular calcium concentration [Ca2+]o from 2 mM to 0.2 mM reduced ACh-induced contractions only at 2.5 g RT with no effect at 0.5 g RT. The nonselective inhibitor of nitric oxide synthase (NOS, NG-nitro-L-arginine methyl ester (L-NAME increased ACh-induced contractions at 2.5 g RT. The inhibitor of inducible NOS, S-methylsothiourea or neuronal NOS, 7-nitroindazole had no effect. At 2.5 g RT, the reduction of [Ca2+]o from 2 mM to 0.2 mM abolished the effect of L-NAME on ACh-induced contractions. The NO precursor L-arginine or the tyrosine kinase inhibitors erbstatin A and genistein had no effect on ACh-induced contractions obtained at 2.5 g RT. Our results suggest that in airways, RT affects ACh-induced contractions by modulating the activity of epithelial NOS in a calcium-dependent, tyrosine-phosphorylation-independent way.

  20. Riik hakkab Via Baltica maanteed neljarealiseks joonistama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Ilmunud ka: Postimees : na russkom jazõke 25. sept. lk. 2. Pärnu maavalitsuse ja maanteeameti eestvedamisel alustatakse Tallinnast Iklani kulgeva Via Baltica liiklussoone teemaplaneeringut, mille järgi tuleb Pärnumaal leida lahendused Are ja Pärnu ümbersõidule ning Nurme õgvendusele. Arvamust avaldab Are vallavanem Jaanus Männik

  1. REŠEVANJE DELOVNIH SPOROV S SODIŠČU PRIDRUŽENO MEDIACIJO

    OpenAIRE

    Goričan Podbrežnik, Sabina

    2016-01-01

    Za človeško družbo je značilno, da se v njej pojavljajo spori.Enega izmed načinov reševanja sporov predstavlja mediacija kot glavni in tipični predstavnik alternativnega reševanja sporov. S sprejetjem Zakona o mediaciji v civilnih in gospodarskih zadevah se je Slovenija pridružila državam, ki imajo zakonsko urejeno mediacijo. Na podlagi Zakona o alternativnem reševanju sodnih sporov pa je mediacija postala tudi del rednega poslovanja slovenskih sodišč. Sodišču pridružena mediacija je edini po...

  2. Model Skinner Operant Conditioning automata i bionički naučeno upravljanje robota

    OpenAIRE

    Cai, Jianxian; Hong, Li; Cheng, Lina; Yu, Ruihong

    2016-01-01

    Fuzzy Skinner Operant Conditioning Automaton (FSOCA) sastavljen je na temelju Operant Conditioning mehanizma primjenom teorije neizrazitih skupova. Osnovno obilježje automata FSOCA je sljedeće: neizraziti rezultati stanja pomoću Gausove funkcije koriste se kao skupovi neizrazitog stanja; neizrazita pravila preslikavanja (fuzzy mapping rules) kod fuzzy-conditioning-operacije zamjenjuju stohastičke "conditioning-operant" skupove preslikavanja. Stoga se automat FSOCA može koristiti za opisivanje...

  3. Pärnu võimukoalitsioon kutsub pataljoni toetama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnu võimuerakonnad kutsuvad linna ja maakonna elanikke kõnekoosolekule, kus nad soovivad avaldada nördimust kaitseministeeriumi plaani üle sulgeda selle aasta lõpul Pärnu üksik-jalaväepataljon

  4. Maavanema avaldus surus linnavõimu kaitsesse / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu maavanem Toomas Kivimägi kritiseeris linnavalitsust Via Baltica Pärnu ümbersõidu projekti venimise pärast. Linnapea Mart Viisitamm ei pea avaldust põhjendatuks. Vt. samas lk. 15: Mart Viisitamm. Demokraatia või diktatuur - selles on küsimus

  5. Pidupäevaüritused olid Eestile ilus kingitus / Andris Tammela, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Tammela, Andris

    2008-01-01

    Ülevaade EV 90. aastapäeva juubeliüritusest Pärnus. Vt. samas: Vabariigi juubel värvis Pärnu sinimustvalgeks; Head emotsioonid Eesti aastapäevalt: Are vallavanem Jaanus Männik, Euroopa Parlamendi liige Marianne Mikko, Pärnu linnavolikogu liikmed Valter Parve ja Raul Sarandi ja Pärnu maavanem Toomas Kivimägi

  6. Abilinnapea tõrjub opositsiooni süüdistusi / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu linnavalitsuse rahanduse abilinnapea Vambo Talu ei nõustu IRL poliitikute süüdistustega, et linna viletsas finantsolukorras on süüdi volikogu loata eelmise aasta eelarvest kärbitud 116 miljonit krooni

  7. Streigi saatus selgub täna lõunaks / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Riiklik lepitaja Henn Pärn tegi viimase kompromissettepaneku. Juhul, kui ametiühingute, tööandjate ja lepitaja kohtumisel osalised seda heaks ei kiida, alustatakse hoiatusstreigiga. Vt. samas: Pärnu streikivate bussijuhtide pöördumine linnarahva poole

  8. Estonia juhti kahtlustatakse ettevõtte varade omastamises / Ester Vilgats, Eno-Gerrit Link, Teet Roosaar

    Index Scriptorium Estoniae

    Vilgats, Ester

    2008-01-01

    Endine Pärnu linnapea, taastusravikeskuse Estonia pikaaegne juht Vello Järvesalu peeti kinni kahtlustatuna ettevõtte varade omastamises suures ulatuses. Kommenteerivad: Mart Viisitamm, Jane Mets ja Ahti Kõo

  9. Päästjatele tuli mullu tuhat väljakutset / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnumaa päästeteenistus sai 2005. a. kõige rohkem väljakutseid Pärnusse ning Via Baltica äärde jäävatesse Pärnumaa valdadesse ja Vändrasse. Kaart: Pärnumaa päästeteenistuste väljasõidud omavalitsustesse 2005

  10. Pärnu linnavalitsuse hinnang esimesele valitsemisaastale / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ajaleht esitas Pärnu linnajuhtidele kolm küsimust. Vastasid linnapea Mart Viisitamm, abilinnapea majanduse valdkonnas Raul Sarandi, abilinnapea arengu ja planeerimise valdkonnas Mart Alliku, abilinnapea kultuuri, spordi ja sotsiaalvaldkonnas Margus Tammekivi ja linnavalitsuse liige turvalisuse valdkonnas Simmo Saar. Arvamust avaldavad Reformierakonna Pärnu piirkonna esimees Väino Hallik ja SDE esindaja Pärnu linnavolikogus Valter Parve

  11. Poliitikud ei leidnud staadioni planeeringule uusi lahendusi / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Riigikogu Pärnumaa saadikuteühenduse ja Pärnu linnavõimu esindajate ning spordiseltsi Kalev juhtide nõupidamine Kalevi staadioni ümberehituse käimalükkamiseks lõppes tulemusteta, sest kõiki osapooli rahuldava tulemuseni ei jõutud. Kommenteerivad Mark Soosaar ja Vello Järvesalu

  12. Sotsid said prostitutsiooni ürituse pärast noomida / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ilmunud ka: Pärnu Postimees 16. märts lk. 3. Pärnu linnavalitsuse kultuuriosakonna peaspetsialist Tair Anton tegi kaubanduskeskuses Port Artur 2 prostitutsiooni vastu vastu allkirju kogunud sotsiaaldemokraatidele loata avaliku ürituse korraldamise eest suulise märkuse

  13. Koalitsioon ei plaani linna juhtimises muudatusi / Ester Vilgats, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Vilgats, Ester

    2008-01-01

    Pärnu koalitsiooninõukogu sõnul pole põhjust linnapea Mart Viisitamme, abilinnapea Simmo Saare ja koalitsiooninõukogu esimehe Vello Järvesalu välja vahetamiseks, kuna kedagi pole süüdi mõistetud

  14. President tunnustab Pärnumaad kümne riikliku autasuga / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Pärnumaalt saavad iseseisvuspäeva puhul riikliku autasu kümme inimest. Vt. samas: Ester Vilgats. Ivar Kaldasaunal on alati kollektiiviga vedanud; Vello Lahtvee kolmkümmend aastat kohtunikuna. Teenetemärgi pälvinute seas on Lääne-Eesti päästekeskuse direktor Ivar Kaldasaun ja Pärnu maakohtu kohtunik Vello Lahtvee. Vt. ka juhtkiri lk. 15: Vilgats, Kalev. Ebaõigluse visa vastupanu. Rüütliristi kavaler Harald Nugiseks jäi taas teenetemärgist ilma

  15. Prospects to solar energy power generation in space. Uchu taiyo hatsuden eno tenbo

    Energy Technology Data Exchange (ETDEWEB)

    Kudo, I. (Electrotechnical Laboratory, Tsukuba (Japan))

    1993-05-01

    Solar energy power generation in space uses large arrays of solar cells developed on a geosynchronous orbit to obtain electric energy, which is transmitted to the earth using microwaves. The idea had already been advocated in 1968, which was followed a decade later by joint discussions done by NASA and DOE. The concept intended to take care of the U.S. power demand by using 60 power plant satellites, each having an output of 5 GW. This expanse of the scale, regarded reasonable even today, calls for the solar cell arrays in space spreading over an area of 10 km [times] 5 km if silicon solar cells with a conversion efficiency of 15% are used, and rectenna on the ground (a received wave converting facility) forming an ellipse of 10 km [times] 13 km (assuming a location at the north latitude of 36[degree]). Although there are a number of problems in the idea such as transportation means to lift construction materials into the space and effect of microwaves on the ionosphere and the ecosystems, the Agency of Industrial Science and Technology organized a 'committee for investigating and studying the space power generation systems' in the fiscal year 1991, and has been moving discussions forward since then. 7 refs., 5 figs.

  16. Application of thermal spray coatings for jet engines. Kokuki sangyo eno yosha no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Muto, Y [All Nippon Airways Co. Ltd., Tokyo (Japan)

    1992-10-31

    Application condition of spray coating on jet engine parts and characteristics of spray reparing process are explained. Spray coating used for jet engine is classified as recovery of dimension, crevice adjustment, improvement of resistance to friction, improvement of fretting resistance and heat resistance. Titanium alloy having better adhesion and acid resistance, is used as coating for dimensional recovery, where as nickel-crome-aluminium coating is used for the improvement of heat resistance of stainless steel, etc. Crevice adjustment coatings are used in rotating parts of jet engines, and they are of two types are; gel-double coating of aluminium, nickel-aluminium, etc., abrasive coating of aluminium oxide. Tungsten carbide and cobalt are used as coatings for the friction improvement. Nickel and indium, etc., are used as fretting resistance coating. Various types of ceramics together with heat resistance steels like HS-188 are used as coating for heat resistance improvement. 4 figs., 3 tabs.

  17. Effect of water pollution on marine organisms; Sekiyu osen no kaiyo seibutsu eno eikyo hyoka

    Energy Technology Data Exchange (ETDEWEB)

    Ogata, M. [Okayama Univ., Okayama (Japan); Fujisawa, K. [Okayama Prefectural Fisheries Experiment Station, Okayama (Japan)

    1997-10-10

    Toxicity of petroleum component to aquatic organisms appears as a result of its deposition onto living organisms followed by its migration into bodies of the organisms, and emergence of toxicity from the migrated component. Effect evaluation processes standing on this viewpoint may include the exposure monitoring or migration monitoring, in which the petroleum component migrated into marine organisms is analyzed and the state of the component concentrated in these organisms is measured, or effect monitoring, in which actions of the petroleum component in the organisms are investigated. The effects of petroleum on aquatic organisms would include the following occurrence: direct fatal toxicity acting on cells and membranes, quasi-fatal toxicity causing death indirectly through feeding actions and abnormal actions, direct coating of oil on surface of organisms, which prevents movability and feeding actions of the organisms and reduces hydrophilicity of plumes and hairs, pollution of living organisms due to migration of carcinogenic aromatic compounds into bodies of the living organisms, and change in species compositions and geographic distribution of living organisms due to change in physico-chemical environment. This paper explains cases of detection and identification of organic sulfur compounds, aromatic compounds, polycyclic aromatic compounds, paraffins, olefins and heavy metals in parametric compounds of petroleum. 20 refs., 4 figs., 3 tabs.

  18. Truncus Arteriosus in a 43 year old Male: Case Report | Ng'eno ...

    African Journals Online (AJOL)

    In truncus arteriosus, the embryologic truncus fails to properly divide in-utero resulting in the pulmonary, aortic and coronary arteries arising from a single ascending portion of this trunk. This condition is usually fatal within the first year of life without correction. Over the past two decades, there has been a dramatic expansion ...

  19. Trial to active seismic while drilling; Jinko shingen wo mochiita SWD eno kokoromi

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, T; Kozawa, T [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1996-10-01

    This paper describes the development of a more stable SWD system with larger energy by adding an artificial seismic source near the bit. SWD is a technique by which the seismic wave generated while drilling of rocks by bit can be observed on the ground surface and the records equivalent to the reverse VSP can be obtained. For this system, a shell with a vibrator was fixed immediately on the bit as a sub-generator, and total energy of usual impact by the bit and vibration by the vibrator was used as a seismic source for SWD. For the seismic wave generation mechanism of this vibrator, the shell was resonated by the magnetostrictive element, and vibration was given to the bit and drilling pipe. When this seismic source is used, only single frequency is obtained for each vibration due to the utilization of resonance of shell. Therefore, the generation patterns should be made, by which wide band energy can be obtained after the interaction. Since the survey was conducted using this bottom hole seismic source at the drilling depth more than 3,000 m, it was necessary to enhance the vibration energy. 2 refs., 2 figs.

  20. Application of EM tomography to detect a buried pipe; EM tomography no maisetsukan tansa eno tekiyorei

    Energy Technology Data Exchange (ETDEWEB)

    Sakashita, S [OYO Corp., Tokyo (Japan)

    1996-10-01

    EM tomography was applied to detect buried pipes. Underground radar exploration method is limited to 10m in depth. Positive use of bored holes is desirable, and in such case, magnetic logging based on the magnetic susceptibility (MS) contrast between buried body and surrounding ground is effective. The primary magnetic field is generated by coil current, and the secondary one is generated by the primary one responding to foreign bodies in the ground. Since the measured primary magnetic field of low frequency within 10Hz can be treated as static magnetic field responding to MS in the ground, it is useful to determine MS distributions. Since the measured magnetic field of high frequency within 100kHz can be treated as induction field responding to conductivity in the ground, it is useful to determine resistivity distributions. The EM tomography which can image both above distributions by using electromagnetic wave in a wide frequency range, was applied to detect buried pipes. The EM tomography could detect an buried foreign body of 3m in diameter at 10m in distance between bored holes. The theoretical equation for analysis was also derived. 5 refs., 9 figs., 1 tab.

  1. Application of wear resistant spraying for diesel engine; Diesel kikan eno taimamo yosha no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kitajima, Y. [Mitsui Engineering and Shipbuliding Co. Ltd., Tokyo (Japan)

    1999-03-31

    Diesel engines used widely as propelling engines of ships have increasingly been provided with a high output and a high thermal efficiency; their structural members, particularly, the component parts for combustion chambers are therefore used under severe conditions, giving rise to the need of surface treatment and surface reforming of the members. Parts for marine diesel engines are huge, so that the technology applicable to the surface treatment and reforming are limited in point of facility and cost; therefore, most suitable is thermal spraying. This paper primarily discusses, among marine diesel engines, a 2-cycle low-speed engine with a 260-980mm bore used for the main engine of a merchant ship such as a container ship, bulk carrier or a tanker, and a 4-cycle medium-speed engine with a 300-420mm bore used for the main engine of a naval vessel; the paper explains the application status of a thermal spraying technology which is in progress to cope with the high output and high thermal efficiency of the diesel engines, explaining particularly the story of the development and the technological features of the wear resistant thermal spraying, which has been put to practical use, on the cylinder liner and the piston ring of the 4-cycle medium-speed engine. (NEDO)

  2. Application of ECS to a hybrid automobile; `ECS` no hybrid jidosha eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, M.; Okamura, T.

    1997-01-30

    This paper describes a simulation for a case when an energy capacitor system (ECS) is mounted in a hybrid electric vehicle in place of secondary batteries. The ECS is electric power storage equipment consisted of capacitors and electronic circuits, and capable of quick charge and discharge at high efficiency. Its energy density per unit weight is about the same as lead-acid batteries, but its output density is greater than any type of batteries. Being free of deterioration due to charge and discharge, its cycle life is almost limitless. In order to suppress heat generation, a switching converter is used to control the output to about 300W. However, internal resistance of an ECS is smaller than in an equivalent secondary battery, and internal loss and heat generation stay as low as 1/5 to 1/10. Discussions have been given on cases of using the ECS in small passenger cars, small buses/trucks, and large buses. Since the ECS can use the stored power to about 94% of the capacity, and its cycle life is sufficiently long, it can operate with charge capacity as small as 1/4 of a lead-acid battery. The weight can also be reduced largely. Regenerative power storage efficiency is high, fuel consumption can be improved, heat generation is less, and no forced cooling is required. 9 refs., 4 figs., 1 tab.

  3. Influence of life line stoppage on building equipments; Lifeline tozetsu no kenchiku setsubi eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Sadohara, S. [Yokohama National University, Yokohama (Japan). Faculty of Engineering

    1995-06-05

    Our daily life is being supported by electricity in various ways. This paper, explains the influence of the stoppage of the electricity, affecting infrastructures, buildings and people`s daily life based on the survey result of a long term electricity stoppage in Hiroshima City in September 1991. This paper also introduces the survey result of emergency generators operation in Japan and in the U.S. Last, the ways and ideas to make lifeline reliability higher in the future are summarized. 1 ref., 11 figs., 7 tabs.

  4. PV glass curtain walls; Kenzai ittaigata taiyo denchi gaiheki no kaihatsu (glass curtain wall eno tekiyo)

    Energy Technology Data Exchange (ETDEWEB)

    Yoshida, T.; Iwai, T.; Ouchi, T.; Ito, T.; Nagai, T.; Shu, I. [Kajima Corp., Tokyo (Japan); Arai, T. [Showa Shell Sekiyu K.K., Tokyo (Japan); Ishikawa, N.; Tazawa, K.

    1997-12-20

    Reported in this article are PV (photovoltaic) modules now under development for integration into building walls. First of all, the power generating capability of PV modules and appropriate use of the generated power are studied, and the performance (resistance to fire or incombustibility, strength and durability, appearance and design, and dimensional standardization) that such outer wall materials are to be equipped with are determined. Next, module development, installation technique, computer graphics-aided facade designing, and real size module-using proof test are studied before installability, the power to be generated, and designs are finalized. In the development of modules, design evaluation involves the combining of various kinds of glass, solar cells, back sheets, and fillers, and the importance is confirmed of the prevention of insulation degradation around the modules. As for the methods of installation, the gasket method and aluminum sash method, etc., are tested. In the study of facade design, it is found that various expressions are possible by properly choosing gasket colors, module types, and kinds of glass to cover the openings. 1 ref., 6 figs., 3 tabs.

  5. Waste minimization activities in Toyota Motor Corporation; Haikibutsu teigen eno torikumi jokyo

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, S.; Yamamoto, N.; Kurai, H. [Toyota Motor Corp., Aichi (Japan)

    1998-07-01

    Toyota`s waste reduction efforts based on a drive for dealing with the source of waste generation are introduced. For the propulsion of the policy for dealing directly with the origin of waste, it is necessary to convert the existing manufacturing processes that give high priority to product quality and low production cost into environmental impact reduction oriented processes. In particular, conversion of materials into those that are easier to recycle, technology for reducing defective products, technology for the completion of recycling within the process involved, and the simplification of all the processes are mentioned. For the cleaning job in the machining process, a detergent enhanced in oil/water separating capability is developed, and this prolongs doubly the detergent replacement period and decreases the waste liquid to a 1/4 or less of what the conventional method produces. For the handling of foundry sand that is yielded in great quantities, a flow classification system is developed to replace the conventional gravitational classifier, and the reusable coarse-grain sand in the collected dust which occupies approximately 70% of the whole waste is now recovered for reuse. In the vehicle body coating process, a newly-developed robot arm type coating system is developed, which halves the coating waste. 2 refs., 9 figs., 1 tab.

  6. Role of biotechnology in future agriculture. Korekarano nogyo to biotechnology eno kitai

    Energy Technology Data Exchange (ETDEWEB)

    Komano, T. (Kyoto Univ., Kyoto (Japan). Faculty of Agriculture)

    1992-09-01

    In comparison with ancient times when everything is handled empirically, biological matter suitable for purposes can be produced and utilized faster and more reliably these days when life science has made a great advance. The advancement is related to new breeding technology and production means, and those means offer the point of contact between biotechnology and agriculture. The application fields of biotechnology are microbiology, cell technology, enzyme technology (bioreactor), and gene engineering. High yield, high content of high value ingredients as foods, adaptability to environment, resistance to disease and insect damage, etc. may be the subjects expected for future agricultural organisms. There may be many areas where biotechnology is related to those organisms, but a discussion is made in this report centering around the problem in breeding. Outlines are given on the applied cases of cell technological method, gene engineering method, and recombinant DNA technology, as well as on gene engineering for plants and animals. 10 refs., 7 figs.

  7. Astronaut suitability requirements and selection process; Uchu hikoshi tanjo eno michi (shishitsu yokyu)

    Energy Technology Data Exchange (ETDEWEB)

    Miyoshi, H. [National Space Development Agency of Japan, Tokyo (Japan)

    1999-10-05

    Manned space activities at National Space Development Agency of Japan and the suitability requirements that an astronaut is supposed to satisfy are described. At the first phase, candidates have to participate in a manned space experiment utilizing a NASA space shuttle and, in 1985, Mori, Mukai, and Doi were selected to be payload specialists. At the second phase, Astronauts Wakata, Doi, and Mori were sent to the mission specialist training course, this being one of the jobs aboard a space shuttle, which was for preparing for the construction and operation of the international space station. In January, 1996, Astronaut Wakata performed extravehicular tool manipulation and so forth, and Astronaut Doi did the same in 1997. The endowments that an astronaut is expected to have include undoubted professionalism, adaptability to branches out of his field, adaptability to a prolonged stay in space, spirit of teamwork and coordination, and ability to perform wide range of duties aboard an international space station. (NEDO)

  8. Projekteerijad asuvad kesklinna võimla kavandit täiendama / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2001-01-01

    Pärnu Vanalinna põhikooli kõrvale kavandatavast võimlast. Võimla eskiisprojektide konkursi võitis (2. koht.) Ott Kadariku ja Mihkel Tüüri töö "Jae-Ja", 3. koha sai Kalle Kadalipu töö "Neo"

  9. Application of essential facility doctrine to transmission grid; Sodenmo eno essential facility no hori no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Maruyama, M. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1997-06-01

    This paper arranges the essential facility doctrine in America and describes it according to each judgment example how the doctrine is applied on the access of electricity supply companies to transmission grids. By applying the result to the situation of Japan, the point at issue occurring in the range of the Anti-Monopoly Law was arranged and investigated when third parties (power generating manufacturers) access the transmission grids of electricity supply companies in the form of wholesale or self transmission in the electricity supply industry of Japan. In the judgment example of America, a transmission grid can be considered as essential facility. The refusal of essential facility application is judged to be illegal only when it aims at keeping and expanding the leading market share without a fair reason. The application of essential facility can be refused when the transmission line is insufficient in capacity, when no necessary technical conditions are satisfied during use, or when the cost generated during use cannot be collected. 18 refs., 7 figs., 2 tabs.

  10. Application of FEM flow analysis to environmental engineering. FEM ryutai kaiseki no kankyo gijutsu eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Higuchi, M; Ando, K; Shimada, S; Umetani, H [Toyota Motor Corp., Aichi (Japan)

    1990-04-25

    In order to apply FEM (finite element method) flow analysis to environmental engineering, the two-dimensional analysis system was developed, and applied to the design of plant ventilation and improvement of an enviromental control equipment. Furthermore, the three-dimensional analysis system was developed to extend its application. Since in a large scale model, no enhancement of a processing capacity was expected even by a supercomputer because of longer I/O times between internal and external memories caused by a small internal memory space, the parallel processing system with multiple external memories was introduced to analyze such models. To achieve more efficient processing, multiple series of renumbering codes were also prepared to optimize the processing order of solvers, elements and nodes. As examples, the improvement of a thermal oxidizer and the ventilation design for a forging plant, and as an example of a three-dimensional large scale model, the flow analysis around a plant were presented. 8 refs., 17 figs., 1 tab.

  11. Application of ceramics to the sliding seat of valve bridge; Valve bridge yodobu eno ceramics tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Matsui, T; Ono, T [Mitsubishi Motors Corp., Tokyo (Japan)

    1997-10-01

    For use in the valve train, using an OHV (over head valve) configuration. of a 4 valve diesel engine for trucks and buses; we developed a valve bridge, a component of a valve train, with a ceramic head that is made of silicon nitride(Si3N4) in contact with a rocker arm in order to reduce cost and improve wear resistance for further diesel engine emissions regulations. In order to evaluate the effect of this valve bridge, RIG tests and durability tests on actual engines were carried out. 7 figs., 2 tabs.

  12. effect of dl-carnitine on tissue content of ad eno ine triphospha te

    African Journals Online (AJOL)

    BSN

    values of 16.2 ± 5.2µ mols lg dry weight for ATP and I 1.7± 2.5 ~11nols/g dry weight for CP in normal (non ischaem1c) myocardial tissue. Continuous perfusion of the heans "ith perfusate contaming 4.9µmols/ml. DL-Carnitine appeared to prevent the lowermg of ATP and CP levels as a result of induction of ischaemia.

  13. Utilization of new materials in prestressed concrete. Shin zairyo no puresutoresuto concrete eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Imai, Y. (Taisei Corp., Tokyo (Japan)); Kato, H. (Building Research Inst., Tokyo (Japan)); Mutsuyoshi, H. (Saitama Univ., Urawa (Japan). Faculty of Engineering)

    1994-03-31

    In this session for the new materials, almost all of them were the presentation on the fiber reinforced plastics (FRP). Based on these facts, the topics of new materials about PC centered around FRP, and consequently it was found that how it was expected as the new materials and how it is being watched with keen interest. Even in FRP, the presentations on the carbon fiber reinforced plastics (CFRP) and aramid fiber reinforced plastics (AFRP) were a little bit more than those on the glass fiber reinforced plastics (GFRP), and therefore they were felt to be predominant. Although the ones about a fundamental study on the material characters of FRP held approximately 70%, as a content, there were 6 presentations on the design and execution of the actual bridges in which FRP was used for the PC take-up materials and the oblique cable of cable-stayed bridges, consequently it was found that FRP did not stay at a study stage, and was already shifting to the actual application stage. However, at the current situation, there were many of experimental ones like the small scale bridges in the golf courses, and furthermore it can not be said that a guideline for the design and execution is sufficiently established. 2 figs.

  14. FY 1975 Report on results of Sunshine Project. Development of techniques of digging high-temperature beds (Researches on roller cutter bits); 1975 nendo koon chiso kussaku gijutsu no kaihatsu. Roller cutter bit no kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-03-31

    It is necessary to establish the techniques for digging bedrocks under elevated temperature and pressure for development and utilization of geothermal energy. This project is aimed at development of heat- and wear-resistant bit cutters, which have efficient tooth edge forms and arrangements. Another factor that determines bit serviceability is the bearing built in a cutter, and this project is also aimed at development of long-serviceable bit bearings by improving their resistance to heat. Four types of bits were developed, on a trial basis, and tested (size: 8.625 inches, two types of tooth forms, different shapes and arrangements of insert tips). They were tested for, e.g., their excavation rate, under the conditions of 5 tons as load and 100 rpm. It is found that their excavation rate vary with load, speed of rotation, tooth height and tooth form. Excavation torque increases in almost proportion to load. The sliding bearings of silver and its alloy were tested, to confirm the effects of silver. It is necessary to conduct the field tests in an actual geothermal area of high rock temperature and the ground tests with test machines to dig heated rocks in and after FY 1975, for overall evaluation of the bits developed. (NEDO)

  15. National research and development project. Report on evaluation of research and development of remotely controlled excavators for highly deep submarine oil fields; Ogata kenkyu kaihatsu project. Daishindo enkaku sosa kaitei sekiyu kussaku sochi no kenkyu kaihatsu ni kakawaru hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-02-04

    Described herein are results of evaluation of the developed excavators remotely controlled for highly deep submarine oil fields. The excavator system was designed to work at the target water depth of 200 to 250 m and excavation depth of 8,000 to 9,000 m, though not quite satisfactorily. There were several practical problems to be solved, e.g., those found in accuracy of reentry in the excavated section, cables connecting the driving equipment to the excavated section, and entangled hoses. The works were divided and system was configured in an attempt to secure all-weather type serviceability and to improve economic viability. The other major works included attempts to improve equipment functions and reduce manpower cost. Nevertheless, however, the construction cost was considered to be higher than expected, and no firm prospect was obtained whether the new excavator system was economically competitive with the conventional rig. The factors that pushed up the construction cost were various facilities needed by the new system with the separated excavation and driving sections, e.g., those facilities for helping the system land on the sea bottoms, material supply/storage facilities, and automated/unmanned facilities. The system failure and other items related to reliability are no clearly understood, making it difficult to compare it with the conventional rig in service factor. It was not adequate, therefore, to advance the next R and D phase as planned, and decided that the project was suspended to see the world development trends, because the clear plans for the future could not be drawn at that time. (NEDO)

  16. FY1997 report on test well drilling and well investigation for the Akinomiya area survey in the geothermal development promotion survey; 1997 nendo chinetsu sokushin chosa. Akinomiya chiiki chosa shisui kussaku koji oyobi kosei chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    In order to extract promising areas with high geothermal feasibility, the Akinomiya area was surveyed by drilling test wells. In the N9-AY-3 excavating work, the first stage (depth from 15 to 33 m) used the water-free excavation to prevent adverse effects on the water sources. The second stage (depth from 33 to 409 m) reached the targeted depth with slanted excavation. The third stage drilled into depths from 409 to 1,006 m. The fourth stage was targeted to drill down to 1,802 m, but an entire lost returns have occurred at the depth of 1,598 m, whereas lost water drilling was performed by using fresh water, and the drilling was terminated at the targeted depth. The AY-4 excavation was also advanced with the first, second, third and fourth stage method, and when the entire lost returns have occurred at 1,196 m, the lost water drilling was carried out by using fresh water, and the drilling was terminated at the scheduled 1,505 m. The AY-5 excavation was also advanced with the first, second, third and fourth stage method. The first and second stages used water-free excavation (using air hammers) to avoid influence on the nearby spa areas. The third stage went down to 405 m performing coring, but the entire lost returns occurred at 298 m. The excavation rate was very high, and the core recovery rate reached 100%. The fourth stage presented the same coring condition as that for the third stage down to 1,002 m. (NEDO)

  17. Study on passive earth pressure acting on the embedment of an earth retaining wall for braced excavation work in cohesive soil; Nenseido jiban ni okeru kussaku dodomeheki neirebu no judo doatsu ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, H. [Pacific Consultants K.K., Tokyo (Japan); Hirashima, K. [Yamanashi University, Yamanashi (Japan). Faculty of Engineering

    1995-12-15

    Passive earth pressure exerts a great influence on the stress and deformation of earth retaining walls in braced excavation. To calculate this pressure, conventional ultimate earth pressure equation, or Rankine-Resals and Coulomb`s equation, are currently applied respectively to cohesive and sandy soil. However, these intentional equation to determine passive earth pressure do not adequately take into account the excavation width during work and the shearing resistance on the earth retaining wall surface. This paper deals with cohesive soil only, deriving a calculation equation for passive earth pressure, which takes into account excavation width and the shearing resistance of the earth retaining wall surface. Then, constants in this equation are determined using the calculation results obtained from the finite element method with blasts-plastic elements. The calculation results are also compared with measured values in the model test in order to check the applicability of the calculation equation for passive earth pressure thus obtained. Finally, this paper proposes a practicable calculation equation for passive earth pressure. 13 refs., 10 figs., 10 tabs.

  18. Fiscal 1999 basic survey report for promotion of joint implementation. Plan for repowering Ashuganji thermal power station; 1999 nendo Ashuganji karyoku hatsudensho no repowering keikaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A study is conducted of a plan to repower the Ashuganji thermal power station, the People's Republic of Bangladesh, with the plan to be connected to the clean development mechanism (CDM). For conversion of the existing No. 3, No. 4, and No. 5 generators (each outputting 150MW) into full fired heat recovery combined cycle generators, 31MW gas turbines are added, one to each of the three. The construction cost is calculated to be 14,000-million yen. Fuel (natural gas) will be saved by 28kt/year/generator, the three saving 2.1-million tons in total in 25 years. There will be a CO2 reduction of 77kt/year/generator, the total reduction to be 5.8-million tons in 25 years for the three generators. Then payback is assessed. In the main case (with the repowering-created increase in output to be used to cover the current power supply shortage), where the internal rate of return of 8.09% is much lower than the discount rate of 15.5% during the 10-year period for payback in case of financing by private funds, the discounted present worth is predicted to be negative and then the project is not feasible. Since there will be no problems about the repayment of borrowed money, however, it is hoped that low-interest special yen credit will be granted for the elimination of chronic power shortage. When it comes to international emission trading (550 yen/ton of CO2), payback is again found to be impossible. (NEDO)

  19. Three-dimensional seismic survey planning based on the newest data acquisition design technique; Saishin no data shutoku design ni motozuku sanjigen jishin tansa keikaku

    Energy Technology Data Exchange (ETDEWEB)

    Minehara, M; Nakagami, K; Tanaka, H [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1996-10-01

    Theory of parameter setting for data acquisition is arranged, mainly as to the seismic generating and receiving geometry. This paper also introduces an example of survey planning for three-dimensional land seismic exploration in progress. For the design of data acquisition, fundamental parameters are firstly determined on the basis of the characteristics of reflection records at a given district, and then, the layout of survey is determined. In this study, information through modeling based on the existing interpretation of geologic structures is also utilized, to reflect them for survey specifications. Land three-dimensional seismic survey was designed. Ground surface of the surveyed area consists of rice fields and hilly regions. The target was a nose-shaped structure in the depth about 2,500 m underground. A survey area of 4km{times}5km was set. Records in the shallow layers could not obtained when near offset was not ensured. Quality control of this distribution was important for grasping the shallow structure required. In this survey, the seismic generating point could be ensured more certainly than initially expected, which resulted in the sufficient security of near offset. 2 refs., 2 figs.

  20. Japan`s Sunshine Project. 1991 annual summary of coal liquefaction and gasification; 1991 nendo sunshine keikaku seika hokokusho gaiyoshu. Sekitan no ekika gas ka

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-01

    Out of the research and development on the 1991 Sunshine Project, the results of coal liquefaction/gasification are reported. The basic research of coal liquefaction/gasification is conducted. The research plan for a 150 ton/day scale pilot plant (PP) is worked out for the development of bituminous coal liquefaction technology by NEDOL process. Data of PSU (Process Support Units) operation, especially, are studied. Concerning the data obtained through dismantling of the 50 ton/day PP in Australia which uses Australian Victoria coal due to completion of its operation and also obtained from its support research, they are reflected in the design of a demonstration plant, and the results are arranged for study. Research and development on refining technology of coal-derived liquid such as Illinois coal liquid and on application technology of its products are made. For the development of coal-use hydrogen production technology, conducted is the research of a high temperature gasification PP by entrained flow bed process which is the core of the coal gasification technology. Elementary study with a 2 ton/day furnace is made for the development of the entrained flow bed coal gasification combined cycle power generation system. Also conducted are PP construction, adjusting operation and the overall research operation.

  1. Summary of FY 1980 results of Sunshine Project. Development of coal liquefaction techniques; 1980 nendo sekitan ekika gijutsu no kaihatsu seika hokokusho. Sunshine keikaku itaku kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    This report summarizes the results of the 3 R and D themes for coal liquefaction techniques, pursued by the Sunshine Project; (1) development of solvent extraction type liquefaction plant, and brown coal liquefaction technique R and D demonstration surveys, (2) development of solvolysis type liquefaction plant, and (3) development of direct hydrogenation type liquefaction plant. For the theme (1), the 1 T/D test plant, solid/liquid separator and small-size continuous settlement separator are constructed, and partly completed. The elementary studies include solvent extraction type liquefaction process, materials for coal liquefaction plant and solid/liquid separation. Australia's Victoria brown coal and Chinese coal are studied to clarify the possible problems involved in liquefaction of these coal species for commercialization of the liquefaction techniques in the early stage. The elementary techniques studied include dehydration of brown coal, milling at high temperature in oil, de-ashing, and secondary and primary hydrogenation. For the theme (2), the 1 T/D plant is inspected and maintained to clarify the problems involved in the continuous operation, revamped and repaired as necessary, given preventive maintenance, and tested for operability confirmation. The elementary studies include solvolysis type liquefaction process, scale-up, hydrogenation plant for solvolysis pitch. For the item (3), the 2.4 T/D test plant is constructed, and the elementary studies are conducted, for, e.g., liquefaction reactions in the presence of an iron-based catalyst. (NEDO)

  2. Present status of promotion of advanced safety vehicle in phase 2 (ASV2); Dai 2 ki senshin anzen jidosha (ASV) suishin keikaku ni okeru kenkyu jokyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-11-01

    For active safety enhancement, drivers will be provided with information and warning that will help them drive with safety. Studies are under way about functions to facilitate drivers' perception and to lighten the burdens imposed on them. As for accident avoidance techniques, onboard systems will perform controls involving vehicle maneuver for safety enhancement. This includes the improvement of vehicle maneuvering performance, in addition to brake control and steering control, for lightening drivers' burdens and for complementing their operating skill. Danger avoidance is based on the concept that the related system is to work in case warnings alone are not enough to avoid a collision. Full automation will be implemented by two ways, the autonomous way aided by the existing infrastructures such as GPS (Global Positioning System) or the way in which infrastructures to be newly built will be utilized. Passive safety technologies aim at minimizing damage upon collision, and involve structural improvement, air bags, etc. Disaster aggravation prevention means to prevent disaster from spreading after collision. Communication is one of safety-related elements on which studies will continue. Under the Phase 2 ASV program, research and development will be conducted for putting passenger cars to practical use, and the same will be conducted, in the case of large vehicles and motorcycles, for the construction of their prototypes. (NEDO)

  3. Summarized achievement report on the Sunshine Project in fiscal 1979. Hydrogen energy; 1979 nendo sunshine keikaku seika hokokusho gaiyoshu. Suiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-04-01

    This paper summarizes the achievement report on the Sunshine Project in fiscal 1979 for hydrogen energy research. In hydrogen manufacturing technologies, the paper describes improvement in membrane performance and discussions on electrode materials in high temperature and pressure electrolysis. In the thermo-chemical method, hydrolysis of iron bromide (II) in the iron system cycle was compared to three kinds of reaction patterns corresponding to phase change, and evaluation was given as the hydrogen generating reaction. In the iodine system the first stage oxidation and reduction reaction of MgO-I{sub 2} was subjected to a continued experiment by using a batch autoclave. Discussions were continued on device materials for the iodine cycle. In the light irradiation electrolytic method for the mixed cycle, the light intensity was experimented at a force 12 times greater than that of the solar beam, and a reaction rate of 80% was achieved. Raising the temperature causes the reaction rate to decline, but it can be supplemented by raising the light intensity. A heat diffusion column was found effective in HI decomposition (hydrogen acquisition). For hydrogen transportation and storage, researches are continued on metal hydrides. In hydrogen utilization technologies, combustion, fuel cells (using high temperature solid and alkaline aqueous solution electrolytes), and hydrogen engines are studied. This paper also describes studies on hydrogen safety assuring measures and energy systems. (NEDO)

  4. Japan`s New Sunshine Project. 1996 Annual Summary of Coal Liquefaction and Gasification; 1996 nendo new sunshine keikaku seika hokokusho gaiyoshu. Sekitan no ekika gasuka

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-11-01

    In reference to the results of the research and development under the fiscal 1996 New Sunshine Project, a report was summed up on coal liquefaction and coal gasification. As to the R and D of coal liquefaction technology, researches were conducted on liquefaction characteristics and engineering properties by coal kind, catalysts for coal liquefaction, liquefaction reaction of coal and reformation utilization of the liquefied products, liquefaction reaction mechanism and coking mechanism, solubility of coal in solvent and catalytic reaction mechanism, solvent reaction mechanism by hydrogen donor solvent, etc. Concerning the R and D of coal gasification technology, made were the basic study of eco-technology adaptable gasification technology and the study of coal gasification enhancing technology. Further, as to the development of bituminous coal liquefaction technology, carried out were the study in pilot plants and the support study of pilot plants. Additionally, R and D were done of the basic technology of coal liquefaction such as upgrading technology and environmentally acceptable coal liquefaction technology, and of coal hydrogasification technology. 3 refs., 81 figs., 25 tabs.

  5. Present condition and theme of the planning standards of parks and open space planning. Koen ryokuchi keikaku gijutsu hyojun no genjo to kadai

    Energy Technology Data Exchange (ETDEWEB)

    Takanashi, M. (Kanagawa Prefectural Government, Kanagawa (Japan))

    1992-08-06

    With the dramatic progress of urbanization, the rapid decrease of the green area and the open space, which is basis for ensuring the safety and the comfort of city life and formation of a good city environment, lead to the worsen of city environment. For the basic purpose of achieving the harmony between development and environment by considering the preservation of the green area and the open space, the green master plan is a representative example, and was made as the constitution of from a ground plan to the various plans such as region, city and nation based on the space unit of developing the human action. One of the important planning approach for the green area plan from conception to implementation is the planning standards of park and open space planning. This paper introduced the change of the system about the planning standards of park and open space planning, and explained necessarily the present state of greens master plan about preservation of the national environment and adjustment the park and open space. 1tab.

  6. Summary of FY 1980 results of Sunshine Project. Development of coal liquefaction techniques; 1980 nendo sekitan ekika gijutsu no kaihatsu seika hokokusho. Sunshine keikaku itaku kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    This report summarizes the results of the 3 R and D themes for coal liquefaction techniques, pursued by the Sunshine Project; (1) development of solvent extraction type liquefaction plant, and brown coal liquefaction technique R and D demonstration surveys, (2) development of solvolysis type liquefaction plant, and (3) development of direct hydrogenation type liquefaction plant. For the theme (1), the 1 T/D test plant, solid/liquid separator and small-size continuous settlement separator are constructed, and partly completed. The elementary studies include solvent extraction type liquefaction process, materials for coal liquefaction plant and solid/liquid separation. Australia's Victoria brown coal and Chinese coal are studied to clarify the possible problems involved in liquefaction of these coal species for commercialization of the liquefaction techniques in the early stage. The elementary techniques studied include dehydration of brown coal, milling at high temperature in oil, de-ashing, and secondary and primary hydrogenation. For the theme (2), the 1 T/D plant is inspected and maintained to clarify the problems involved in the continuous operation, revamped and repaired as necessary, given preventive maintenance, and tested for operability confirmation. The elementary studies include solvolysis type liquefaction process, scale-up, hydrogenation plant for solvolysis pitch. For the item (3), the 2.4 T/D test plant is constructed, and the elementary studies are conducted, for, e.g., liquefaction reactions in the presence of an iron-based catalyst. (NEDO)

  7. Color landscape plan of the concrete Consideration on the harmony of concrete and landscape; Konkurito no shikisai keikan keikaku. Keikan to konkurito no chowa wo kangaeru

    Energy Technology Data Exchange (ETDEWEB)

    Akiyama, Hiroshi [Landscape Planning and Design with Concrete and Color, Tokyo (Japan)

    1999-03-10

    In Ministry of Construction, they positively promote the natural river make, and they have announced the basic design with the aim of river which does not use the concrete and river in which the concrete is not seen. It is the design control in using the concrete to be necessary for this. They introduced color landscape plan of the pile block of the concrete as a case in aiming at the harmony of concrete and landscape of being more concrete. They introduced concrete product which could express the local color characteristics of colors of the concrete which it does not suit for the landscape, usage of the concrete, concrete of the warm color, colors of concrete product of France, examples of the Disneyland, colors concrete lied, landscapes and cost, etc. (NEDO)

  8. Collection of summaries of Sunshine Program achievement reports for fiscal 1982. Hydrogen energy; 1982 nendo sunshine keikaku seika hokokusho gaiyoshu. Suiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1983-04-01

    The collection includes achievements of research relating to hydrogen energy. In the research on hydrogen production by electrolysis, electrolysis of water using an acid-type solid polymer electrolyte and electrolysis of water using an alkali-type solid polymer electrolyte are taken up. In the research on hydrogen production by thermochemical methods, studies are conducted on the iodine-based cycle, the bromine-based cycle, materials for devices for the iodine-based cycle, and the mixed cycle. Hydrogen production using high-temperature direct thermolysis and solar radiation is also studied. In the research on hydrogen transportation and storage, use of metallic hydrides in these processes are taken up. In the research on the application of hydrogen, techniques of hydrogen combustion and hydrogen-fueled engines are discussed. In the research on hydrogen safety measures, technologies for the prevention of hydrogen explosions and of hydrogen embrittlement of materials in use with hydrogen are studied. In addition, a study is conducted of a hydrogen energy total system, and research and development is carried out for a plant that produces hydrogen by high-temperature high-pressure electrolysis of water. (NEDO)

  9. Report on the coal energy achievements in the Sunshine Project in fiscal 1988; 1989 nendo sunshine keikaku seika hokokusho. Sekitan energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-07-01

    This paper describes the achievements in the Sunshine Project in fiscal 1988 in studies on coal liquefaction. The liquefaction mechanisms may be conceived to work in the following three manners: radicals produced by spontaneous bond and cleavage of coal molecules draw out hydrogen from the donor and stabilize it; bond, cleavage and stabilization due to hydrogenation from the donor to coal aromatic nucleus; and cleavage and stabilization due to work of active hydrogen discharged from the donor. How these mechanisms contribute to composition of the products depends on coals, liquefying conditions, and reactivity of the donor. Selection of the donor solvent requires design by which high liquefaction yield can be obtained with small amount of solvent. The oil plus asphaltene yield could have been approached to the ideal value through the moving liquefaction of gaseous phase hydrogen and catalyst-free hydrogen, with the 4HFL to coal ratio at 1.5 to 1. The gaseous phase hydrogen was found effective in reducing 4HFL. Liquefaction residual oil manufactured from Morwell brown coal subjected to BCL was hydrogenated in single stage or two stages to compare and discuss the solvent sorting constituents, reactivity of CLVR, and how the catalytic activity deteriorates. The cause for the catalyst deterioration was elucidated, and considerations were given on catalysts and reaction conditions for lightening and refining of CLVR. (NEDO)

  10. Japan`s New Sunshine Project. 1994 annual summary of solar energy R and D program; 1994 nendo new sunshine keikaku. Seika hokokusho gaiyoshu (taiyo energy)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-12-01

    The paper reported the results of fiscal 1994 studies on solar energy in the New Sunshine Project. Relating to the technical development for the practical use of photovoltaic power systems, the development of manufacturing technologies for low-cost substrates and the development of element technology for manufacturing low-cost polycrystalline cells/modules were reported as the development of technology for thin substrate polycrystalline solar cells for practical use. As to the research on fabrication technology for thin film solar cells for practical use, reports were made on the research on low-cost fabrication technology for large-area modules and the technological development for qualitative improvement, etc. In respect to the technological development for super-high efficiency solar cells, reported were the technological development for super-high efficiency single crystalline silicon solar cells and the technological development for crystalline compound solar cells, etc. Concerning the research and development of photovoltaic power systems, reports were on the characterization and control of surface/interface recombination velocity of crystalline silicon thin films and the research on surface passivation for high-efficiency silicon solar cells, etc. In regard to the utilization technology of solar thermal energy, the energy conversion technology using chemical reactions and the development of chemical refrigeration and cold storage systems using solar heat were reported as the research and development of utilization technology of solar thermal systems for industrial use.

  11. Study on the detached house plan using of a maximum natural energy. Part 1; Shizen energy fukugo riyo no keikaku ni kansuru kenkyu. 1

    Energy Technology Data Exchange (ETDEWEB)

    Wada, I; Mino, M; Miyata, T; Okawa, M [Nihon University, Tokyo (Japan)

    1996-10-27

    The geographical position or environment is set on the assumption that the natural energy of a detached house is used in a hybrid state. Moreover, the energy consumption of the house and the natural energy supply obtained from the geographical position were compared and investigated. As a result, the energy consumption is 10,617 kWh, and the energy supply is 8,236 kWh. About 78% of the whole consumption can be theoretically made from natural energy. The energy supply is calculated on the low side during prediction. Therefore, an increase in the energy supply is expected by installing a solar collector based on solar energy, expanding the solar panel area, and increasing the number of wind mills. However, this energy is partially lost via an inverter while it is supplied to the general domestic equipment. At the six main points in Tokyo and its districts, the adaptability of natural energy used based on the regional characteristics is investigated presently and the installation of a system is examined. 13 refs., 2 figs., 6 tabs.

  12. Global environment action plant of Japan Society of Civil Engineers. ; Agenda 21 / Japan Society of Civil Engineers. Doboku gakkai chikyu kankyo kodo keikaku. ; Agenda 21 / doboku gakkai

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-15

    This paper explains the involvement of the global environment action plan of Japan Society of Civil Engineers, Agenda 21, with civil engineerings and global environmental problems, as well as the global environment action plan. Global environmental problems require handling the matters in three ways: identification and elucidation of events, effect analysis estimation, and alleviation, avoidance and prevention of the effect. Settlement and proliferation of civil engineering technologies transferred to developing countries demand indispensably understanding such features of the developing countries as social and economic conditions, natural conditions, climates, histories, races, and cultures. Realizing the sustainable development requires the followings: formation of civil engineerings that contribute to improving global environments; development of civil engineerings that make coexistence of human being and other living organisms possible; analyses of effects and mechanisms of global warming and weather change and the corresponding technique and system development; and development of techniques to build resource circulating type national land and cities. It is also essential to move forward positively structuring civil engineerings that contribute to solving such global environmental problems as acid rains and marine pollution, and technical development thereof; providing guidelines on execution of international civil engineering constructions, and technical development thereof; developing civil engineerings in developing countries and assisting training of people.

  13. Japan's New Sunshine Project. 1998 annual summary of hydrogen energy R and D; New sunshine keikaku 1998 nendo seika hokokusho gaiyoshu. Suiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-04-01

    Summarized herein are the reports on R and D efforts on hydrogen energy, as part of the FY 1998 New Sunshine Project. For production of hydrogen, characteristics related to transport number were investigated for steam electrolysis at high temperature, in which a sintered ceramic powder was used as the electrolyte and the cell was equipped with platinum electrodes. For utilization of hydrogen, energy conversion techniques were investigated using hydrogen occluding alloys for testing methods for alloy microstructures and hydrogenation characteristics, and preparation of and performance testing methods for the cathodes charged with the aid of hydrogen gas. For analysis/assessment for development of hydrogen-related techniques, the investigated items included water electrolysis with solid polymer electrolytes, hydrogen transport techniques using metal hydrides, hydrogen storing techniques using metal hydrides, hydrogen engines, and techniques for preventing hydrogen embrittlement. Analysis/assessment for development of hydrogen turbines was also investigated as one of the 12 R and D themes reported herein. (NEDO)

  14. Collection of summaries of Sunshine Program achievement reports for fiscal 1981. Hydrogen energy; 1981 nendo sunshine keikaku seika hokokusho gaiyoshu. Suuiso energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-04-01

    The collection includes research on hydrogen production through the electrolysis of water using an acid-type solid polymer electrolyte, electrolysis of water using an alkali-type solid polymer electrolyte, thermochemical method using an iodine-based cycle, thermochemical method using a bromine-based cycle, thermochemical method using a mixed cycle, high-temperature direct thermolysis, and the utilization of solar radiation. Furthermore, it includes a study of materials to build a iodine-based cycle apparatus. In a research on the transportation and storage of hydrogen, technologies of hydrogen transportation and storage using metallic hydrides are taken up. In a research on the application of hydrogen, technologies of hydrogen combustion and hydrogen-fueled engines are discussed. In a research on hydrogen safety measures, technologies for the prevention of hydrogen explosion disasters and of hydrogen embrittlement of materials in use with hydrogen are studied. In addition, a study is conducted of a hydrogen energy total system, and research and development is carried out of a plant that produces hydrogen by means of the high-temperature high-pressure electrolysis of water. (NEDO)

  15. Some studies on structural planning of long-span cable stayed bridge; Choshikan shachokyo no kozo keikaku ni kansuru 2,3 no kosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Endo, T. [NKK Corp., Tokyo (Japan)

    1997-06-20

    Feasibility of cabled-stayed bridges with 1000m-grade spans is discussed while re-examining the plan for constructing a Great Tatara Bridge to connect Honshu and Shikoku, Japan, and in this process various tasks and questions are isolated. Some which will be problems in designing the new bridge structure are taken up, including the load-bearing capability of the bridge as a whole, vibration of long cables, resistance to long-period earthquakes, and accuracy management during the construction work. Findings are stated below. A cable-stayed bridge is not significantly different from a suspension bridge and is sufficiently feasible until the span exceeds 1500m. When the span is longer, however, the bridge beam cross section needs be designed very prudently in view of the great axial force and wind load to be imposed on it. Effective for the assurance of load-bearing capability for a long-span cabled-stayed bridge is a structure in which load is elastically confined in the direction of the bridge axis. In connection with vibration damping for very long cables, it is verified that a new dimpled cable suits the purpose of suppressing wind load from increasing without reduction in damping effect. 28 refs., 23 figs., 7 tabs.

  16. Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS)

    DEFF Research Database (Denmark)

    Bath, Philip M W; Woodhouse, Lisa; Scutt, Polly

    2015-01-01

    BACKGROUND: High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether to continue or temporarily withdraw existing antihypertensive drugs, is not known. We assessed outcomes after stroke in patients given drugs......·91-1·13; p=0·83), and with continue versus stop antihypertensive drugs OR was 1·05 (0·90-1·22; p=0·55). INTERPRETATION: In patients with acute stroke and high blood pressure, transdermal glyceryl trinitrate lowered blood pressure and had acceptable safety but did not improve functional outcome. We show...

  17. Study about the effect of microgravity on biofunctions; Seitai kino eno bisho juryoku no eikyo ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A study is made for the elucidation of the effect of microgravity on biofunctions. The protoplast of shiitake is exposed to microgravity and then cultured, and a significant difference occurs. The rate of colony formation by cell fusion in the test sector is found to be two times higher than that in the control sector. When swimming ciliates which are unicellular are suddenly exposed to microgravity, their swimming speeds changed differently according to the direction of swimming. When a mouse subjected to acupuncture for three days is exposed to microgravity, its water metabolism and excretory function are enhanced. A mouse treated with Chinese medicine reacts in the similar way. The change due to microgravity in the amount of acetylcholine in the hypothalamus is found characteristically time dependent. Mice infected with lethal herpes viruses just after exposure to microgravity die at a rate in proportion to the number of exposures and to the amount of viruses given. The migration speed of chemical stripes in case of a gel-base BZ (Belousov-Zhabotinsky) reaction under microgravity is equal to that on the ground. The trigger wave migration speed in case of a water solution-base BZ reaction under microgravity is reduced to approximately 80% of the speed on the ground. 12 refs., 31 figs., 3 tabs.

  18. Report to the Nuclear Regulatory Commission from the staff panel on the Commission's determination of an Extraordinary Nuclear Occurrence (ENO)

    International Nuclear Information System (INIS)

    1980-01-01

    The Panel finds that the first criterion, pertaining to whether the accident caused a discharge of radioactive material or levels of radiation offsite as defined in 10 CFR 140.84, has not been met. It further finds that there is presently insufficient information to support any definitive finding as to whether or not the second criterion, relating to damage to persons or property offsite as defined in 10 CFR 140.85, has been met. Since the Panel has not found that both criteria have been met, it recommends that the Commission determine that the accident at Three Mile Island did not constitute an extraordinary nuclear occurrence

  19. Optimum design of automobile seat using statistical design support system; Tokeiteki sekkei shien system no jidoshayo seat eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kashiwamura, T [NHK Spring Co. Ltd., Yokohama (Japan); Shiratori, M; Yu, Q; Koda, I [Yokohama National University, Yokohama (Japan)

    1997-10-01

    The authors proposed a new practical optimum design method called statistical design support system, which consists of five steps: the effectivity analysis, reanalysis, evaluation of dispersion, the optimiza4ion and evaluation of structural reliability. In this study, the authors applied the present system to analyze and optimum design of an automobile seat frame subjected to crushing. This study should that the present method could be applied to the complex nonlinear problems such as large deformation, material nonlinearity as well as impact problem. It was shown that the optimum design of the seat frame has been solved easily using the present system. 6 refs., 5 figs., 5 tabs.

  20. Adaptation of topology optimization on truck-structure; Kinshitsukaho ni yoru iso saitekika shuho no truck kozo eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Tachibana, H; Kojima, A; Chiba, S [Mitsubishi Motors Corp., Tokyo (Japan)

    1997-10-01

    An optimization using the homogenization method has been applied to a truck-structure on the concept design stage. A truck-structure is grouped into 3 classes (thin plate structure , thick plate structure and solid structure), then example, effectiveness and method for the application for the purpose of weight reduction , high rigidity and high eigen-frequency are introduced. 3 refs., 24 figs., 1 tab.

  1. Role of iNOS and eNOS expression in a group of Egyptian diabetic and nondiabetic nephropathy patients

    Directory of Open Access Journals (Sweden)

    Mayssa I. Aly

    2013-01-01

    Conclusion The presence of iNOS is associated with tubular damage resulting in renal failure. The upregulation of NO in diabetes mellitus type 2 may explain the endothelial dysfunction that is associated with almost all diabetic complications.

  2. Latest trends in variable speed drive systems. ; Application to elevators. Kahensoku drive system no saishin doko. ; Elevator eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Inaba, H. (Hitachi, Ltd., Tokyo (Japan))

    1992-07-12

    The history of the elevator development may be summarized as a challenge to heights of buildings, pursuit of energy saving, and realizing comfort. Transfer of its drive system to the inverter drive system has been nearly completed keeping the pace with advance of electronic technologies. This paper describes control systems of elevators, effects of introducing inverters, and future trends. The inverter system used widely now for standard elevators with a speed lower than 105 m/min consists of a converter to rectify the utility power, a regenerative power consuming circuit to suppress overvoltage in the DC stage, and an inverter to supply power to induction motors. Those elevators exceeding a 120 m/min speed use power regenerating inverter system, with its converter controlled using micro computers according to loads and speeds of motors. The inverter system is particularly marked for having realized energy saving, lower power consumption, lower environmental pollution (from harmonics), comfort and maintainability at high levels. 13 refs., 9 figs.

  3. Kinnisvaraäri ajas Pärnu linnajuhid omavahel tülli / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2008-01-01

    Pärnu linnavolikogu esimees Ahti Kõo peab ebaeetiliseks linnapea Mart Viisitamme ja spordiseltsi Põhjakotkas juhatuse esimehe Ivar Hallopi vahel sõlmitud ühtse kavatsuse protokolli. Ilmunud ka Pärnu Postimees 17. nov. lk. 1

  4. Pärnu leivatööstusest võib saada sakslaste allhankija / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pere Leib Tootmine plaanib kolida leiva-saia tootmise suuremas osas Tartusse ja keskenduda Pärnus eksporttoodete valmistamisele Saksa turule. Arvamust avaldab Pere Leib Tootmise juhatuse liige Eero Mikenberg

  5. Rapala landitehas püüdis tänavugi suurima kala / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Maailmakuulsa landitootja Rapala Pärnus Reldori tööstuskülas asuv tehas pääses teist aastat järjest Pärnumaa aasta ettevõtete edetabeli etteotsa. Diagramm: Rapala Eesti ASi majandustulemused. Vt. samas: Pärnumaa ettevõtete tipp 50

  6. Häädemeeste vallavanem jäi kihutamise pärast jalameheks / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Ilmunud ka: Postimehes 9. nov. lk. 5 lüh.Korduva kiiruseületamisega silma paistnud Häädemeeste vallavanem Urmas Aava peab viimase kihutamise eest kuuks sõiduõiguseta jätmist liiga karmiks karistuseks

  7. MiR-21 is induced in endothelial cells by shear stress and modulates apoptosis and eNOS activity

    International Nuclear Information System (INIS)

    Weber, Martina; Baker, Meredith B.; Moore, Jeffrey P.; Searles, Charles D.

    2010-01-01

    Mechanical forces associated with blood flow play an important role in regulating vascular signaling and gene expression in endothelial cells (ECs). MicroRNAs (miRNAs) are a class of noncoding RNAs that posttranscriptionally regulate the expression of genes involved in diverse cell functions, including differentiation, growth, proliferation, and apoptosis. miRNAs are known to have an important role in modulating EC biology, but their expression and functions in cells subjected to shear stress conditions are unknown. We sought to determine the miRNA expression profile in human ECs subjected to unidirectional shear stress and define the role of miR-21 in shear stress-induced changes in EC function. TLDA array and qRT-PCR analysis performed on HUVECs exposed to prolonged unidirectional shear stress (USS, 24 h, 15 dynes/cm 2 ) identified 13 miRNAs whose expression was significantly upregulated (p · ) production. These data demonstrate that shear stress forces regulate the expression of miRNAs in ECs, and that miR-21 influences endothelial biology by decreasing apoptosis and activating the NO · pathway. These studies advance our understanding of the mechanisms by which shear stress forces modulate vascular homeostasis.

  8. Introduction of electric double layer capacitors in the solar-EV; Solar denki jidosha eno denki nijuso condenser no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujinaka, M [Tokyo Denki University, Tokyo (Japan)

    1996-10-27

    A basic experiment was carried out on a supplementary power supply, in which solar cells and electric double layer capacitors(EDLC) were combined for a DC/DC converter, for the use of a solar-electric vehicle (S-EV); and in actuality, an S-EV was loaded with the power supply with a running test conducted on a public road. The EDLC was found effective and useful for avoiding temporary lowering of voltage and momentary break. An electric supply was thereby made possible for an emergency light without the use of the DC/DC converter. However, in a tunnel or a night driving and in case of failure of the DC/DC converter, an operating time of only 7 minutes or so was affordable with the EDLC having a capacity of 100F. Moreover, particularly with a heavy load, it was impossible to maintain a voltage for many hours. Under the circumstances, an S-EV design would primarily require two sets of independent DC/DC converter loaded in the future. The EDLC, young after it was developed, still has a small energy density compared with a lead storage battery. Yet, an EDLC with a higher performance being developed, there is a possibility that it will be applied to S-EV`s by utilizing its characteristics such as a high efficiency and a long service life. 4 refs., 8 figs.

  9. Estimation of the charge quantity from solar cell to battery; Taiyo denchi ni yoru chikudenchi eno juden yosoku

    Energy Technology Data Exchange (ETDEWEB)

    Tsutsumi, K; Nishitani, M [Daiichi University, College of Technology, Kagoshima (Japan)

    1996-10-27

    In performing an experiment of running a small electric vehicle by installing solar cells in it and by charging the storage battery at a specific voltage, an estimation was made on the charge quantity to the battery for each solar altitude and inclination of a module at different hours. The solar altitude was determined at Daiichi University, College of Technology, according to the month and the time of day from a formula using day-declination and time equation of a chronological table of science. The quantity of global solar radiation was determined by resolving the solar radiation into its direct and diffuse components on the basis of the extra-terrestrial solar radiation quantity with the change in radius vector taken into consideration; and then, the global solar radiation on the inclined face was obtained from the angle of inclination and incidence. On the roof of a Daiichi University building, solar cell modules were installed facing north and south at 0{degree}, 30{degree}, 45{degree}, 60{degree} and 90{degree} each, so that a short-circuit current was measured for each differently inclined angle. As a result of the experiment, shown in an regression formula is a relation between the temperature conversion value of the maximum output of the solar cell at the standard temperature of 25{degree}C and the quantity of solar radiation on the inclined surface. Consequently, it enabled the prediction of a charging quantity, in the case of running a small vehicle with solar cells installed, from the quantity of solar radiation on the inclined surface in the clear weather. 2 refs., 4 figs., 2 tabs.

  10. President tunnustab Eesti riigi edendajate elutööd / Silja Joon, Ester Vilgats, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Joon, Silja, 1966-

    2008-01-01

    Pärnumaalased, kes pälvivad iseseisvuspäeva puhul ja Eesti riigile osutatud teenete tunnustamiseks president Toomas Hendrik Ilveselt riiklikud autasud. Juuresolevatel fotodel Valgetähe V klassi ordeni pälvinud koorijuht ja muusikaõpetaja Toomas Voll ja Kotkaristi IV klassi teenetemärgi pälvinud Lääne prefektuuri politseiametnik Kalvi Almosen. Vt. ka lk. 1: Enn Hallik. Tatjana Jaanson üllatus suurest aust. Sõudetreener pälvib Valgetähe IV klassi teenetemärgi

  11. Application of laser cladding to the aeroengine component. Koku engine buhin eno laser nikumori yosetsu no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Morita, A [Ishikawajima-Harima Heavy Industries, Co. Ltd., Tokyo (Japan)

    1991-08-01

    Keeping the pace with recent development and application of laser cladding, hard-facing is used more frequently on turbine blades made of superalloys used in aeroengines. This paper explains the basic principles and features of laser hard-facing technique, welding parameters, and examples of practical use. Examples of practical use include application to turbine blades used in ALF502R-5 turbo fan engines for commuter aircraft and high-pressure turbine blades used in RB211 turbo fan engines for large passenger aircraft. In the former engine, improvement of abrasion resistance was intended at the shroud section where blades are in contact with each other, for which inconel was used as the base material and CO-group alloy as the welding material. The welding used a powder supply system with a laser generator oscillating CO{sub 2} at 5 kW and employing a beam collecting mirror plus scanner to attain a beam covering wider width. Faces with higher performance were obtained than by the conventional TIG welding, and the finishing time was decreased largely. 2 refs., 9 figs., 3 tabs.

  12. Crankshaft strength and rigidity analysis and application to shape optimization; Crank jiku kyodo gosei kaisekiho to keijo saitekika eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Numajiri, S [Mitsubishi Motor Corp., Tokyo (Japan); Tamura, Y [Mitsubishi Automotive Engineering Co. Ltd., Tokyo (Japan)

    1997-10-01

    A crankshaft bending stress analysis method using an elastically supported continuous beam model has been established based on the exact evaluation of the stress concentration at fillet R sections and the crankshaft rigidity. Through various examinations, it was revealed that the calculation results of the bending stress well agreed with the actual measurements. This allowed the reliability analysis and the rigidity analysis to be used to determine optimized crankshaft specifications and web shape, which in turn made it possible to apply this method to the weight reduction of a crankshaft (material removal from web). 1 ref., 7 figs., 1 tab.

  13. Power feeding to terminal devices in optical subscriber network; Hikari fuaiba tsushin ni okeru tanmatsu kiki eno kyuden

    Energy Technology Data Exchange (ETDEWEB)

    Yamasaki, M

    1998-09-01

    This paper outlines present state of the feeding system in the light access system in consideration of backup in case of home power failure. In the optical communication, equipment with bilateral conversion function for light and electricity has to be installed both on communication service side and home side. Outline of the light access system and equipment requiring backup are shown. The following items are explained: main types of the light access system, such as FTTC (fiber to the curb), FTTP (fiber to the pole), FTTH (fiber to the home) and HFC (hybrid fiber coax), and the feeding system; problems on feeding system for the light access system. Key elements of ONU (optical network unit) for FTTH and construction of the ONU power source are illustrated. The ONU power source is composed of a backup power supply unit and main body supply unit. Backup power is indispensable to the ONU and analog telephones: output is supplied by the backup batteries in power failure. For miniaturization of the backup power source, power supply circuits and backup batteries have to be miniaturized simultaneously. History of miniaturization is explained on the experimental models. 6 refs., 7 figs., 1 tab.

  14. Role of civil technology towards environmental conservation and creation; Kankyo hozen/sozo eno doboku gijutsu no yakuwari

    Energy Technology Data Exchange (ETDEWEB)

    Kato, T. [Maeda Corp., Tokyo (Japan)

    1995-01-15

    The recent circumstances domestic and abroads around `environment` are showing a kaleidoscopic movement with the Earth Summit in 1993 as a turning point, such as the materialization of the Environmental Fundamental Law, enactment of environmental policy fundamental principle by the Ministry of Construction, and furthermore and adoption of the earth environmental action plan-agenda 21-by the Japan Society of Civil Engineers. Under the circumstances like this the civil work execution study committee has planned this panel discussion for study, for a purpose of catching hold of the environmental problem from a standpoint of the actual constructor and furthermore searching for what should be done. As a consequence, the various opinions have been presented as follows: Namely, in order to grapple with the environmental problems it is required for that a co-operation work of the civil engineers should be done with the people in the other field. As for the environmental problems, a discussion forecasted for the future is necessary. Because an environment itself is fuzzy matter, it would be better not to give the too clear solution for a concept. An attitude to make much of the matter which can not be counted is needed. The mitigation (influence alleviation countermeasure) is required for applying flexibly.

  15. Realization of an accelerator for environmental refreshment in case of soil; Fukyugata kasokuki ni yoru kankyo sosei eno koka

    Energy Technology Data Exchange (ETDEWEB)

    Isogai, H [Electrotechnical Laboratory, Tsukuba (Japan)

    1997-11-25

    Learning from a history of the earth of ancient times, the paper studies effects of refreshing environment and soil or making them natural and harmless mostly using primitive bacteria, and develops element technology which is industrially accelerating. The spread type accelerator working only by solar energy was installed and operated for experiment. As indices of refreshment effects, a study was comparatively made between a sugar degree of sweet potato and a yield shown in the number of potatotimesunit weight. An EM propagation garbage layer is formed, and the two sections were installed of a site of the actual installation of the spread type accelerator and a site naturally left alone. Other effects of weather, temperature and humidity which are external factors and general fertilization are offset as common modes, and a consideration was so made that only refreshment effects of primitive bacteria can be relatively compared. Acceleration effects in using accelerator for growing sweet potato could be quantitatively confirmed. As to sugar degree, because the last study was made in the beginning of summer, the underground temperature was high enough. Even only EM effects were fully effective. This time, the weather was much colder, and it was found to be a must to use accelerator. 2 figs.

  16. Port Artur 3 arhitektuurikonkursi võidutöö sündis Itaalias / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2006-01-01

    Pärnu kesklinna jõeäärse ala rahvusvahelise arhitektuurikonkursi tulemustest. Võitis itaalia arhitektide projekt "Flood". Teise koha võitis projekt "Istu ja vaata" (Jan Skolimovski ja Peeter Loo), kolmanda koha "Nicesaar" (Ott Kadarik, Villem Tomiste, Mihkel Tüür)

  17. Approach to load leveling in Kansai Electric Power Co. Inc.; Kansai Denryoku no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-09-01

    This paper presents an electric hot-water heater and ice storage air conditioning system as systems to be recommended for load leveling. Electric hot-water heater is featured by safety, cleanliness, silence and convenience because of no use of fire. Its electricity charge is only 7.15 yen/kWh less than 1/3 of that for ordinary homes because of use of midnight power. Mainly used MPU-control type electric hot-water heater is more economical because of a 15% discount system. Ice storage air conditioning system is operated in the daytime using ice made by midnight power. It is featured by reduction of facility and installation costs due to the small capacity of heat source equipment, use of inexpensive midnight power, and reduction of running cost due to small contract demand. However, since an ice storage air conditioning system is in the initial stage of diffusion, its initial cost is expensive as compared with conventional non-heat storage air conditioning systems, remaining the issue of cost reduction. 3 figs., 1 tab.

  18. Load levelling measures being tackled by shikoku Electric Power Co. Inc.; Shikoku Denryoku Kabushi Kaisha no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    For the electric power companies, the activity of pushing forward the load levelling contributes greatly to the curtailment of cost by means of effective formation and utilization of facilities. It is planned to take up more positive activities with a target of 3% improvement in the load factor in ten years. Concrete measures for further promotion of load levelling are the diversity of the rate menu of appraising the load levelling effort of the customers and the promotion of the spread of equipment and systems relating to load levelling such as electric water heating apparatuses and thermal energy storage air conditioning systems. The rate system has been reviewed taking the opportunity of rate revision made in January, 1996. Particularly, further load shift to midnight time zone is expected as a result of better rate incentive for customers which is brought about by large reduction of the rate level due to the cost reduction effect accompanying the improvement in atomic power generation ratio. Outlines are given on the fields relating to general households, business, dwellings, buildings, and industry. 3 figs., 1 tab.

  19. Approach undertaken by our Company for leveling electric loads; Chubu Denryoku Kabushi Kaisha no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-07-01

    Measures for leveling the electric loads relying upon two facets - tariff system and business activities - in Chubu Electric Power Co., Inc. are presented. Firstly, the existing pricing systems for midnight electric power and electric light according to the period of time for the household as well as those of seasonal and time zone electric power, modifiable contract with the time zone and so forth for large industry users, together with a similar contract for the owner of regenerating installation are outlined. In addition, a price reduction system is indicated in favor of a scheduled shutdown of large industry operations as a means of avoiding electric consumption during weekdays in summer and between 13h and 16h when large demands exist. Further, a selective contract system put in service in 1995 and the price reduction for ice regenerating air conditioning system are cited. As for business facet, 1995 is regarded as the first year of the ice regenerator for its generalization through exhibition and promotive campaign to the foods processing industry, and the application of the latent heat regenerative system to perishable foods is recommended. Moreover, installation of energy saving type automatic vending machine, so-called eco-vendor is encouraged for its merit of peak-cut and energy price lowering. Lastly, activities to extend the use of electric calorifiers and the regenerative floor heating are mentioned. 2 figs., 1 tab.

  20. Load leveling efforts of The Hokkaido Electric Power Co. Inc.; Hokkaido Denryoku no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    The Hokkaido Electric Power Co., Inc., aiming to enhance power generation efficiency through power load levelling, strives to expand and substantiate its electricity billing menu and to popularize and encourage the use of levelling-oriented apparatuses and systems most of which are designed for utilizing midnight power. The billing menu has in it a snow-melting power which is cut off for load levelling during the peak demand time zone. For domestic use, a time zone-specified lighting system named Dream Eight is created, which is one of the billing systems dependent upon time zone. Introduced therein for industrial use is a demand/supply adjustment contract system. Furthermore, in compliance with the amended Electricity Business Law that came into force in 1995, efforts are under way for revising the period wherein power is to be supplied for melting snow, expanding the scope of application of the power supply system dependent upon time zone, and newly introducing a heat accumulation assisted peak adjustment contract system and an operation adjustment contract system. As for business efforts in relation to load levelling, the company proposes household electrical systems centering about 200V high-efficiency apparatuses, electric water warmer contributing to the enhancement of year-round load levelling, popularization and reinforcement of electric snow melting systems, and power utilizing technologies capable of meeting local demands raised for example by agriculture and fishery.

  1. Investigation of load leveling in Hokuriku Electric Power Co., Inc.; Hokuriku denryoku no fuka heijunka eno torikumi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-08-01

    Hokuriku Electric Power Co., Inc. aims at an around 2% improvement of the load factor up to 2005, by which the quick and proper service and the proposal of load leveling menu are planned. This paper describes an outline of the investigation of load leveling. Various programs have been proposed so that the customers can further shift the load by their consideration. Proposed systems include the time-of-day electricity rate system, the load regulation contract system for industries, the seasonal time-of-day rate system, the electric power system for snowmelt in which the load is dumped at the peak, and the secondary electric power system for snowmelt. Accompanying with the revision of electric utility law, the enlargement of its available time, the price reduction, and the discount rate system for the ice regenerative air conditioners have been provided. For the business activities, a demonstration model house was exhibited to indicate a proper house with local characteristics in Hokuriku district. Furthermore, the spreading activities of regenerative systems and the consulting activities have been positively promoted. 4 figs., 1 tab.

  2. Efforts of load leveling in Tohoku Electric Power Co. Inc.; Tohoku denryoku no fuka heijunka eno torikumi ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This paper describes efforts of load leveling in Tohoku Electric Power Co., Inc. from the viewpoint of the rate system and business development. For the approach from the rate system, various rate menus for the peak shift have been arranged for domestic and large industry customers. To create the midnight demand, spread and expansion of electric hot water service are promoted. Consequently, the contract of midnight power has reached 914,000 kW at the end of 1995, which was 774,000 kW in 1985. To spread the ice regenerative air conditioning systems, the grant of incentive to the manufacturers and special discount of electricity rate have been conducted. These systems have been introduced in the eight places of Tohoku Electric Power`s business. The spread incident system has been created to introduce the automatic vending machines for beverages with the power peak cut function. Unused energy, such as exhaust heat from the non-treated sewage water and substations has been utilized as a heat supply project for city redevelopment. Multi-functional heat pump with regenerative function has been developed. This system aims at the peak shift by combining multi-functional heat pump and electric hot water service. 2 figs., 2 tabs.

  3. Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis

    NARCIS (Netherlands)

    Mugoni, V.; Postel, R.; Catanzaro, V.; De Luca, E.; Turco, E.; Digilio, G.; Silengo, L.; Murphy, M.P.; Medana, C.; Stainier, D.Y.; Bakkers, J.; Santoro, M.M.

    2013-01-01

    Protection against oxidative damage caused by excessive reactive oxygen species (ROS) by an antioxidant network is essential for the health of tissues, especially in the cardiovascular system. Here, we identified a gene with important antioxidant features by analyzing a null allele of zebrafish

  4. Application of CO2 laser cutting machine to shipbuilding; Zosen no setsudan eno CO2 laser no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujimoto, Y. [Mitsui Engineering and Shipbuilding Co. Ltd., Tokyo (Japan)

    1998-11-01

    Carbon dioxide laser has been applied to cutting works in shipbuilding. As NC cutter was obsolete, CO2 laser cutting machine with a rated output 3 kW was introduced. According to the specifications of the machinable plate, the maximum thickness is 19 mm, and effective width and length are 5.4 m and 29.1 m, respectively. As the cutting width is wide and the running distance of laser beam is long, the error of light axis is expanded only by a small error of irradiation angle, which results in the inconvenience. Stable operation was realized by improving the fixation of reflecting mirror. Right angle cutting section with a cutting curve below 0.5 mm was obtained, and cutting time was reduced by the one-line cutting by which both sections can be available with a single cutting line. For the cutting of thin plate with a thickness less than 10 mm, strain was not formed, and remedy was not required. Block strain was remarkably reduced during the assembly process. Maintenance-free operation without monitoring can be performed for a long time. This machine is operated at night and lunch time, resulting in the reduced processes. The working environment is appropriate without noise and dust. Facility cost and maintenance cost were also reduced. Lower cutting speed is a weak point, when compared with the plasma cutting machine. The present machine is not applied to aluminum plates with high surface reflectivity. 13 figs.

  5. enos a ochrana informací v mobilních telekomunikacích

    OpenAIRE

    Pacák, Pavel

    2011-01-01

    Charles University in Prague Faculty of Arts Institute of Information Studies and Librarianship Study program: Information Studies and Librarianship Field of study: Information Studies and Librarianship Pavel Pacák The transfer and protection of information in mobile telecommunications Bachelor thesis abstract The work focuses on the transfer and protection of information in mobile telecommunications. First, historical development of each technology used is introduced. Also different forms of...

  6. Ecological processes for Environmental Impact Assessment in Coastal Waters; Engan no kankyo eikyo hyoka (EIA) eno seitaigakuteki apurochi

    Energy Technology Data Exchange (ETDEWEB)

    Ishikawa, Kimitoshi. [Environmental Assessment Dept., Tokyo (Japan)

    1999-03-25

    This paper focuses on a method for estimating adverse effects on natural environment by economic development in coastal waters in Japan. In particular, the most critical relations concerning the impact on marine organisms is pointed out and discussed according to an environmental impact assessment. Relations between environmental impact assessment and marine organisms needs a quantitative ecological approach in order to succeed in sustainable development of coastal waters management. Recently, the Environment Agency of Japan pointed out the unreliability and the theme on accuracy and the staff for biology and ecology in the environmental impact study. Ecological response to environmental impact occurs in a wide spectrum of physiological and biological and biological functions. Therefore biological monitoring measures must correspond to the given time-space scale of natural mechanisms. For the evaluation of environmental impact, it is desire able to develop of experimental technics and collect biological and ecological basic data for the object. I Reconstructing the following: 1. Reconstructing a clearlistic EIA process by EIA agencies and practitioners, 2. Scorping the biological and ecological issues by EIA professionals, 3. Using the current computer technology, 4. Considering monitoring systems over scales of time and space for the ecological target and 5. Making available to public all monitoring data and reports of EIA. (author)

  7. Application fo tunneling and atomic force detection to machines and scientific instruments. Tunnel gensho ya genshikan no mechatronics eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kawakatsu, H. (The University of Tokyo, Tokyo (Japan). Institute of Industrial Science)

    1991-11-01

    It is now about ten years since the scanning tunnel microscope (STM) and the atomic force microscope (AFM) were invented. These microscopes are used very importantly today as a surface analyzer capable of atomic order analysis for their very high resolution. The STM and AFM obtain images of atomic orders by means of mechanical scanning of the probes. This means that the microscopes can control positioning, force detection and displacement in regions of sub-nanometer orders. Examples of researches may include detection of acceleration, length measurement, positioning, force detection, nano-tripology, processing and gravitational wave detection. As described above, this paper notes the researches derived from the operational principles of the STM and AFM, rather than the researches on the observation objects. The great diversity of the researches taken up and the greatness in the number of researches in the STM and AFM gather how superbly germinative these were. 34 refs.

  8. Astronaut training plans and training facilities in Japan; Uchu hikoshi tanjo eno michi (kunren to kunren setsubi)

    Energy Technology Data Exchange (ETDEWEB)

    Harada, C. [National Space Development Agency of Japan, Tokyo (Japan)

    1999-10-05

    Introduced are the training of astronauts for duties aboard a space shuttle, training provided by NASDA (National Space Development Agency of Japan), and training facilities. The astronaut candidate training course involves space science, space medicine, ocean science, and others, in addition to flight training aboard the T-38 jet trainer, emergency procedure training, shuttle system training, weightlessness training aboard the KC-135 jet plane on a ballistic flight, and SCUBA training. After candidates are named to serve aboard the space shuttle, they are to undergo training related to the shuttle system, emergency exit, adaptation to the surroundings, and the space laboratory system. As for ISS (international space station), astronauts will have to construct the station, and to stay there for a long time operating and maintaining the station and manipulating various experimental apparatuses. The astronaut training process in Japan covers approximately four years, including candidate training, advanced training, and mission dependent training. The training facilities include a weightless environment test system, low-pressure environment adaptation training system, etc., available at NASDA's Tsukuba Space Center. (NEDO)

  9. Ilves viskas koos Bedwettersiga näppu. President Ilves kohtus õpilaste ja kaitseliitlastega / Eno-Gerrit Link

    Index Scriptorium Estoniae

    Link, Eno-Gerrit

    2007-01-01

    Münchenis MTV Euroopa muusikaauhindade jagamisel Uue Euroopa Heli kategoorias lauluga "Dramatic Letter to Conscience"esikoha võitnud Pärnu pop-punkbändist Bedwetters ja president Toomas Hendrik Ilvese Pärnu Sütevaka humanitaargümnaasiumi ja Kaitseliidu Pärnumaa maleva külastusest 9. novembril

  10. Application of genetically engineered microorganisms to bioremediation and wastewater treatment. Idenshi sosa biseibutsu no kankyo joka mizushori eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, M; Ike, M [Osaka University, Osaka (Japan). Faculty of Engineering

    1993-11-10

    This paper summarizes the following techniques: a gene engineering method for bioremediation and wastewater treatment, microorganism breeding using the former method, and a monitoring technique for genetical and ecological stability of genetically engineered microorganisms. Recombination bacteria reinforced with PH genes showed higher phenol removing rate than wild strains, but presented accumulation of catechol in such a large quantity as cannot be seen in wild strains, with the complete degradation rate rather decreased. Gene recombined bacteria structured by introducing the recombined plasmid, pBH500, had high genetic stability when P.putida BH-1 is used as a host. E.coli C600 having recombined plasmid and P.putida BH were added and cultivated in activated sludge. As a result, both recombined bacteria showed rapid logarithmic decrease just after the addition, then, maintained the relatively stable population groups, and remained in the activated sludge for an extended period of time. In monitoring techniques, the colony hybridization process detected clearly the gene recombined bacteria. 9 refs., 7 figs., 1 tab.

  11. Report to the Nuclear Regulatory Commission from the staff panel on the Commission's determination of an Extraordinary Nuclear Occurrence (ENO)

    Energy Technology Data Exchange (ETDEWEB)

    None

    1980-01-01

    The Panel finds that the first criterion, pertaining to whether the accident caused a discharge of radioactive material or levels of radiation offsite as defined in 10 CFR 140.84, has not been met. It further finds that there is presently insufficient information to support any definitive finding as to whether or not the second criterion, relating to damage to persons or property offsite as defined in 10 CFR 140.85, has been met. Since the Panel has not found that both criteria have been met, it recommends that the Commission determine that the accident at Three Mile Island did not constitute an extraordinary nuclear occurrence.

  12. Design and erection of the MUSEUM BRIDGE; Bijutsu no sekai eno yume no kakehashi. MUSEUM BRIDGE no sekkei seko

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, S.; Tsunekawa, M.; Umda, A.; Kishimoto, Y.; Yotsukura, Y.; Miitsu, K.; Okada, S.; Furukawa, M. [Kawasaki Heavy Industries, Ltd., Kobe (Japan)

    1998-12-20

    MUSEUM Projects for the religious corporation of Shinji-Shumeikai, at Shigaraki, Shiga prefecture. Fundamental design was by a project team led by the world-famous architect I.M. Pei. The museum is located in a prefectural park surrounded by forests. The design concept of the bridge aimed to connect Shangri-La (museum) to the real world. In order to satisfy this purpose, a cable-stayed bridge with external tendon was adopted as an original structure style, and details such as handrails, gratings, and gloss painting taken into consideration. The authors report the characteristics of the bridge and the sequence of erection. (author)

  13. FY 1975 Report on results of Sunshine Project. Development of techniques of digging high-temperature beds (Development of solid bits and air-friction bearings); 1975 nendo koon chiso kussaku gijutsu no kaihatsu. Solid bit oyobi air friction bearing no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1976-03-31

    A combination of superhard alloy and diamond powder has been widely used as the solid type edge. The solid type with only a superhard alloy edge is no better than the traditional metal bit. It is ironical to admit that one of the most important items in the development of solid bits for digging high-temperature beds is not related to high temperature itself but development of highly efficient, long serviceable bits, growing out of the inefficient digging mechanisms for the conventional solid bits. It is considered that use of a superhard alloy edge is disadvantageous for digging hard rocks in the so-called scratching manner, for the two major reasons: (1) a superhard alloy is certainly resistant to wear, but nothing to that of diamond, and (2) it is homogeneous and lacks directional properties, such as the cleavage plane of diamond, which is effective for cutting. This project is aimed at development, on a trial basis, and eventual commercialization of new types of solid bits serviceable for extended periods by drastically improving suerhard alloys to provide them with new structures, e.g., those corresponding to the crystal axes of diamond, and also introducing a concept of crushing. (NEDO)

  14. Report on research and development achievements in fiscal 1980 in Sunshine Project. Development of a high-temperature bed drilling technology (Feasibility study on high-temperature bed drilling); 1980 nendo koon chiso kusaku gijutsu no kaihatsu seika hokokusho. Koon chiso kussaku ni kansuru feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    Discussions were given on feasibility of a technology to drill efficiently a high-temperature bed (350 degrees C and 400 kg/cm{sup 2}) to 3 to 5 km. This paper summarizes the bit items for development (bearings, cutters, blade tips, sealing materials, a tip retaining method and structures). The roller cutter bit had the retaining power of the mother cutter material strengthened by using improved carbonized steel and heat treatment. A bit bearing using heat resistant material showed a life of 40 hours or longer at 350 degrees C. The solid bit using a two-layered ultra hard blade tip achieved a drilling rate of 0.84 m/h without any breakage. Studies were also advanced on the air friction drilling method. This paper also dwelled on heat and corrosion resistant blade tips, materials, enhancement of heat resistance in powder sintered cutters, and studies on the bit sealing. In addition to discussions on the percussion drilling as a new drilling method, discussions were given on slanted drilling, air drilling and multi-leg drilling. The paper summarizes these discussions together with development problems to be solved in the future. Research and development works were carried out also on an explosion preventing device, a roll packer, and a rotating head prevent device. (NEDO)

  15. FY 2001 report on the results of the development of the hydrothermal utilization power plant, etc. Development of collecting technology for deep geothermal resources (Development of drilling technology for deep geothermal resources); 1992 - 2001 nessui riyo hatsuden plant tou kaihatsu sokatsu seika hokokusho. Shinbu chinetsu shigen saishu gijutsu no kaihatsu - Shinbu chinetsu shigen kussaku gijutsu no kaihatsu (2001 nendo seika hokokusho bessatsu shiryo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-03-01

    For the purpose of developing deep geothermal resources, development of 'drilling technology of deep geothermal resources' was made from FY 1991 to FY 2001, and the results were summarized. As to the development of bits, the bit that can be used for 30 hours or more at a temperature of 250 degrees C was developed, and the demonstrative test was made in FY 1997. Relating to the development of the high temperature use drilling mud, the mud that can be used at a temperature of 350 degrees C was developed, and the test using the actual well was conducted in FY 1997. Concerning the development of the high temperature use cement slurry, the cement slurry with specific gravity of 1.35 or below that can be used under the environment of a temperature of 350 degrees C was developed, and the hanging test of the specimen was made in the actual well in FY 1998. About the development of the high temperature use downhole motor, a prototype of 1/12 scale was fabricated in FY 1998, and the performance test at high temperature was conducted. As to the development of the high temperature use high strength cement slurry, a cement slurry with specific gravity of 1.50 or below and compressive strength of 19.61 MPa that is used under the environment of a temperature of 300 degrees C was developed, and the test on the long-term compressive strength was made in FY 2001. (NEDO)

  16. Fiscal 1998 investigation of geothermal development and promotion in Akinomiya area survey. Report on exploratory drilling/well survey and incidental work (1/2); 1998 nendo chinetsu kaihatsu sokushin chosa Akinomiya chiiki chosa hokokusho. 1/2. Shisui kussaku koji kosei chosa oyobi futai koji

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-01-01

    Exploratory drilling and well survey were conducted, for the purpose of grasping underground geological structure, temperature and physical properties of Akinomiya area, Akita prefecture, as a part of fiscal 1998 investigation of geothermal development and promotion. The exploratory drilling well N10-AY-6 was excavated to the depth of 1,701 m. This well had a small lost circulation of about 4.2 kL/h at the end of drilling; hence, pressurized water injection was carried out for the purpose of enhancing the performance as a reducing well, resulting in an improvement to 21.6 kL/h. The well N10-AY-7 was in the bedrocks of the Old Tertiary system at the depth of 492 m or deeper, which revealed that the Old Tertiary bedrocks lay more shallowly than expected. At the depth of 1,900 m, the maximum temperature showed 223.3 degree C. In a temperature recovery test, it climbed to 277.2 degree C at the depth of 1,400 m. In the well N10-AY-8, the Old Tertiary bedrocks were found drilled at the depth of 87 m or deeper. Inside well temperatures at the time of temperature recovery test showed nearly the same degrees from the depth of 880 m to 1,090 m or about, thereafter rising until the depth of 1,330 m, further rising from 1,370 m until the bottom of the well, and showing the maximum temperature of 277.0 degree C at the depth of 1,450 m. (NEDO)

  17. Report on research and development achievements in fiscal 1980 in Sunshine Project. Development of a high-temperature bed drilling technology (Research and development of bit materials); 1980 nendo koon chiso kussaku gijutsu no kaihatsu seika hokokusho. Bit zairyo no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-03-01

    Development is made on bit materials that can efficiently drill high-temperature ground bed to 3,000 to 5,000 m under geothermal conditions of 350 degrees C and 400 kg/cm{sup 2}. Alloy composition excellent in corrosion resistance, oxidation resistance, high-temperature hardness, and repulsion resistance without decreasing damage resistance lower than the existing products is Cr{sub 3}C{sub 2} amount of 1%, WC of 2.5 microns, and Co/(Co + Ni) of 50%. Dispersion strengthening is most suitable for a metallurgically sintered powder cutter. Adding carbide of 5% by volume or metal as dispersion strengthening particles enhances hardness almost without damaging tenacity. Compression yield has also increased. Good dispersion strengthened materials include W and WC. On cutter materials for rock drilling bits used under severe conditions of high temperatures, high pressures, and corrosion environment, natures nearly close to the target were provided, and prospect for shape provision was obtained. These natures include mechanical properties at elevated temperatures, corrosion and wear resistance, an inside strengthening method, and a surface hardening method. Dispersion strengthening by adding micro fine hard powder to the inside strengthening method was used to have obtained the intended achievement. Positioning of the metallurgically sintered powder was made clear. (NEDO)

  18. Survey of selecting the promising drilling points out of the ground survey of the FY 1992 geothermal development promotion survey. Soil gas survey (No.C-1 - Shirotori area); 1992 nendo chinetsu kaihatsu sokushin chosa. Chijo chosa no uchi yubo kussaku chiten sentei chosa (Dojo gas chosa) hokokusho (No. C-1 Shirotori chiiki)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    As a part of the survey of selecting promising drilling points, survey was made using soil gas to grasp the area of existence of geothermal fluid in the area for careful examination and the locational distribution of fractures controlling the behavior of fluid. In the survey, the concentration of Hg in soil gas/carbon isotopic ratio of CO2 were measured at 247 measuring points. Generally speaking, there existed the hydrothermal fluid along the structure controlling geothermal activities in the area where the concentration of Hg in soil gas is high, and the volcanic gas as a heating source of geothermal fluid was rising in the area where the carbon isotopic ratio is high. In the survey, areas where both the Hg concentration and the carbon isotopic ratio were high were extracted as promising areas where the high temperature geothermal fluid possibly exists. The promising areas extracted were the periphery of the Daiichi (No.1) Shirotori Hot Spring, periphery of KT-4, southern periphery of N4-ST-2, periphery of 54E-OBN-1 - 54E-OBN-2, and periphery of N4-ST-2. Besides, a possibility of existence of geothermal fluid was indicated in the northeast of N4-ST-1 and in the northeast of KT-9. (NEDO)

  19. Development of hot water utilizing power plants in fiscal 1999. Development of technology to collect geothermal resources in great depths/Development of technology to excavate geothermal resources in great depths (Designing whole development); 1999 nendo nessui riyo hatsuden plant nado kaihatsu seika hokokusho. Shinbu chinetsu shigen saishu gijutsu no kaihatsu / shinbu chinetsu shigen kussaku gijutsu no kaihatsu (zentai kaihatsu sekkei)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Technological development has been made on excavation of geothermal wells, which are dense, hard, and high in temperature and pressure, in developing geothermal resources in great depths. This paper summarizes the achievements in fiscal 1999. This fiscal year has performed the excavation test using an actual well to verify the reliability in practical use of the developed heat-resistant and durable bit. The test was executed by using a bit with a diameter of 8-1/2 inches in a ground bet having a maximum temperature of 300 degrees C in the Yamakawa geothermal field. As a result, good site evaluation was obtained that the wear and tear after lift-up showed no problems, and sufficient performance was verified in the drilling rate and durability. In addition, the low specific gravity cement for high temperature use that has been newly developed was given a cement mixing test to identify its workability at site and hardening properties, at a test well with a temperature of about 40 degrees C in the Okiri geothermal field. The actual well test was performed in a large-scale lost water occurred in a return well during an excavation by Nittestu-Kagoshima Geothermal Company. Effects were recognized in measures to prevent water loss. (NEDO)

  20. FY 1999 report on the results of the development of high efficiency lightning conversion compound semiconductor. Plan on lighting for the 21st century; Kokoritsu denko henkan kagobutsu handotai kaihatsu seika hokokusho. 21 seiki no akari keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of developing the white light-emitting diode (LEDs) lightening as 'a plan on lighting for the 21st century,' the results of the following R and D were obtained: 1) basic study of light-emitting mechanism; 2) improvement of epitaxial growth method of blue/ultraviolet LED; 3) substrate for homoepitaxial growth; 4) basic characteristics of phosphor-based light source for white LED lighting. In 1), light emitting mechanisms responsible for high-quantum efficiency of InGaN mixed semiconductors and InGaN/GaN quantum wells were studied by means of temperature-dependent photoluminescence (PL), time-resolved PL and selective-excitation PL spectroscopy. In 2), precise lapping and polishing procedures of sapphire and GaN crystalline substrates for epitaxial growth using metalorganic chemical-vapor-deposition and MBE showed favorable surface characteristics of substrates. In 3), study was made on growth conditions and growth mechanism of GaN bulk single crystals using the nitrogen pressure-controlled solution growth method. A size of 12mm diameter of GaN single crystal showing good crystallinity and PL characteristics were obtained. In 4), excitation, absorption and PL spectra of rare-earth doped Y{sub 2}O{sub 2}S red phosphor were studied in detail. (NEDO)

  1. Research report for fiscal 1998. Basic research for the promotion of joint implementation etc. (Ryazanskaya thermal power station modification program); 1998 nendo kyodo jisshi nado suishin kiso chosa Ryazanskaya karyoku hatsudensho kaishu keikaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Under study is the modification of the four antiquated 300MW brown coal-fired power plants of the Ryanzanskaya thermal power station. Under the modification program, the plants will be burning a mixture of 60% coal and 40% natural gas for an increase in efficiency and for a great decrease in greenhouse gas emission. The amount of greenhouse gas emission of 6,858,592 tons/year before the modification will be reduced by 19.4% to 5,532,198 ton/year. The budget for the modification will call for 719,731,700 US dollars. EIRR (economical internal rate of return) is calculated based on the figures provided by the Russian office concerned about the current fuel cost and the current rates for the supply of electricity and heat. It is found that EIRR fluctuates depending on the ruble/dollar exchange rate. Although it does not pay at the current exchange rate, yet, when a US dollar is worth 13.0 rubles, an EIRR of 15% will realize at an availability factor of 70%. The same result is obtained when the availability factor is 80% and a US dollar is worth 14.8 rubles. There is a plan to fire the plants with 100% natural gas in the future. If the plan is implemented, a modification to incorporate gas turbine combined cycle will become feasible. (NEDO)

  2. Basic investigation on promotion of joint implementation in fiscal 2000. Energy conservation and modernization plan for Chhatak Cement Co., Ltd.; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Chhatak Cement sha shoene, kindaika keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    With an objective of saving energies and reducing greenhouse gas emission, discussions were given on a modernization plan for the Chhatak cement factory in The People's Republic of Bangladesh. The Chhatak cement factory having a nominal production capability of 267,000 tons a year uses mainly wet-type long kilns of old type, consuming a great amount of natural gas. The present plan has discussed adoption of the Japanese energy saving technologies. The technologies use a vertical roller mill for raw material pulverization, a suspension preheater and a short kiln for clinker sintering, a grate cooler for clinker cooling, and the pre-crushing system. The result of the discussions provided the prospects of reduction in the natural gas consumption at 50%, and reduction of electric power consumption at 16%. This will mean the annual reduction of about 22,000 tons as converted to crude oil. The CO2 reduction amount would reach 51,800 tons a year. The total investment amount would be US$37,327,000. The result of the financial analysis according to the case studies appears severe, wherein reduction of the various expenses is desired possibly by the finance from Japan with generous conditions.(NEDO)

  3. FY 2000 report on the basic survey to promote Joint Implementation, etc. Project for the modernization of the Tashkent cogeneration plant; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Tashkent netsuheikyu hatsudensho kindaika keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    An investigational study was carried out of the project for energy conservation and greenhouse effect gas emission reduction by introducing the newest and most powerful gas turbine cogeneration facilities to the Tashkent cogeneration plant in Uzbekistan. At the Tashkent cogeneration plant, each of the facilities is being superannuated, which leads to lowering of operational reliability and increase in cost of repairs. In the project, studied was the introduction of the newest and most powerful gas turbine cogeneration facilities with heat output of 100 Gcal/h equivalent to that of one can of the existing hot water boiler and with generated output of 80MW. As a result of the study, obtained were the energy conservation amount of 83.9 ktoe/y and the greenhouse effect gas reduction amount of 179.7 kt-CO2/y. The initial investment amount was 10.003 billion yen. Expenses vs. effects were 8.39 toe/y-million yen in energy conservation amount and 18.0 t-CO2/y-million yen in greenhouse effect gas reduction amount. In the study of profitability, the internal earning rate was 9.24% after tax, the return yield of capital was 41.26%, and the period of ROI was 16.9 years. (NEDO)

  4. FY 1980 Report on results of Sunshine Project by Coal Group. Basic researches on coal liquefaction techniques by solvolysis; 1980 nendo sunshine keikaku sekitanhan hokokusho. Sekitan no solvolysis ekika gijutsu no kiso kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1981-07-01

    The basic experimental researches were carried out for coal liquefaction by solvolysis. The studied items include hydrogenation conditions for treating the primary liquefied products, asphalt, pitch and model solvents (e.g., anthracene oil) in the presence of a commercial catalyst, solvolysis conditions for finely divided, molten coal using a hydrogenation recycled solvent, hydrotreating solvents, analysis of solvolysis-liquefied products, and liquefaction capacity of fractionated solvents for finely divided, molten coal. The studied items for separation of minerals include settlement at high temperature of the solid residue from the first liquefaction stage, and changed coal particle size distribution as a result of the first-stage liquefaction reactions in the presence of a hydrogenation solvent. The experimental study results indicate that conversion of finely divided molten coal into asphaltenes and preasphaltenes is notably accelerated in the phase-II coal liquefaction process by solvolysis, when a hydrotreating solvent is used for the first stage solvolysis process. (NEDO)

  5. Collection of outlines of Sunshine Program achievement reports for fiscal 1988. Solar energy (Light utilizing technology and heat utilizing technology); 1988 nendo sunshine keikaku seika hokokusho gaiyoshu. Taiyo energy (hikari riyo gijutsu / netsu riyo gijutsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1989-04-01

    Collected concerning the research and development of photovoltaic power systems are the basic research on solar cells; research and development of new-type photovoltaic power systems; and research and development of amorphous solar cells. Collected concerning the development of technologies for the practical application of photovoltaic power systems are the experiment, refining, and verification of low-cost silicon; experiment, fabrication, and verification of solar panels; research on the practical application of high-efficiency crystal-based solar cells; research and development of amorphous solar cells; research and development of solar cell evaluation systems; development of peripheral technologies; research and development of photovoltaic power-aided systems; research and development of centralized photovoltaic power systems; and development of photothermal hybrid type photovoltaic power systems. Collected concerning heat-utilizing technologies are the research and development of solar thermal electric power generation systems; research and development of solar air-conditioners and hot water supply systems; and development of practical application technologies for industrial solar systems. Collected also are international cooperative projects on solar energy technologies. (NEDO)

  6. Collection of outlines of Sunshine Program achievement reports for fiscal 1989. Solar energy (Light utilizing technology and heat utilizing technology); 1989 nendo sunshine keikaku seika hokokusho gaiyoshu. Taiyo energy (hikari riyo gijutsu / netsu riyo gijutsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-04-01

    Collected concerning the research and development of photovoltaic power systems are the basic research on solar cells; research and development of new-type photovoltaic power systems; and research and development of amorphous solar cells. Collected concerning the development of technologies for the practical application of photovoltaic power systems are the research on the practical application of new-type solar cells; research on the practical application of amorphous solar cells; research and development of solar cell evaluation systems; research and development of peripheral technologies; research and development of photovoltaic power-aided systems; research and development of centralized photovoltaic power systems; and research and development of photothermal hybrid photovoltaic power systems. Collected concerning heat application technologies are the research and development of solar thermal energy systems; development of practical application technologies for solar systems for industrial use etc.; and cooperative projects between Japan and Australia etc. on solar energy technologies. (NEDO)

  7. New Sunshine Project for fiscal 1997 on the international cooperation project. Cooperation in solar energy technologies among Japan, Australia and other countries; 1997 nendo new sunshine keikaku kokusai kyoryoku jigyo. Nichigo nado taiyo energy gijutsu kyoryoku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes the state of progress in the cooperation in solar energy technologies among Japan, Australia and other country, the memorandum concluded for the new project, and the activity report on the NEDO/MUERI project. The progress in the cooperation in solar energy technologies among Japan, Australia and other country is divided into that of the new project and that of the continued project. The former relates to the start of the long-term endurance test project for photovoltaic solar modules in Oman. The location of the endurance test is the Sultan Qaboos University in the suburb of Muscat. Modules subjected to the endurance test consist of ten modules of five types. The test will be performed on air temperature, humidity, wind directions, insolation on horizontal surface, insolation on slanted surface, ultraviolet ray intensity, module temperatures, and electric characteristics of the modules. The continued project is an outdoor endurance test for the photovoltaic solar modules begun in fiscal 1996, which is executed by the Murdock University Energy Research Institute (MUERI). The endurance test locations were selected at Darwin, Alice Springs and Perth. This paper reports the photovoltaic solar module endurance test and investigation, as well as the periodical consultations as the activity report of the NEDO/MUERI project. (NEDO)

  8. Research and development of a high-temperature superconducting flywheel energy storage system. Research and development of the New Sunshine Program; Furaihoiru denryoku chozo shisutemu kenkyu kaihatsu. Nyu sanshain keikaku ni motozuku kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Nakagawa, Y. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1999-11-25

    The project conducted by NEDO for developing a high-temperature superconducting flywheel energy storage system is introduced; the two test results of fundamental studies are described. One is the measurement of levitation force and rotation loss of superconducting magnetic bearings composed of oxide superconducting bulks and permanent magnet composite. Two types of superconducting magnetic bearings. axial and radial types, were fabricated and tested. The other test was the fabrication and testing of two functional models. A small-sized superconducting flywheel model of the 0.5 kWh class was fabricated and tested. A medium-sized rotating functional model of the 10 kWh class was fabricated as well. (author)

  9. Research report for fiscal 1988. Basic research for the promotion of joint implementation etc. (plan for using combined cycle at Konakovo Power Station, Russia); 1998 nendo kyodo jisshi nado suishin kiso chosa. Roshia renpo KONAKOVO hatsudensho combined cycle ka keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    On the basis of Kyoto Protocol-provided flexible measures such as joint implementation and clean development mechanisms, a study is conducted for introducing combined cycle into Konakovo Power Plant of Russia currently equipped with antiquated eight 300MW power plants constructed in the 1960's for which early renovation is necessary. The power station is an important power source connecting to the Moscow-Petersburg main. The gas turbine combined facilities to be newly installed will comprise 250MW-class state-of-the-art gas turbines arranged in four blocks, capable of a total output of 1600MW at a thermal efficiency of 58% (with simultaneous supply of heat). Four units capable of 1200MW out of the existing units will stay in operation for load adjusting. Since the price of power is set low under government control, the accounting capital/internal return rate is as low as 2.3%. The rate recalculated under the financing conditions of special yen credit for environmental protection, however, is as high as 19%, so high as to make the renovation an economically feasible project. It is expected that there will be an annual CO2 reduction of 2.3-million tons or a reduction of 57.50-million tons in 25 years (the life span of the new facilities). The renovation may be a joint implementation project to which both Japan and Russia will attach the highest priority. (NEDO)

  10. Fiscal 1996 New Sunshine Plan auxiliary project. Report on results on development of coal hydrogasification technology (Support research); 1996 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu shien kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    R and D was conducted for the purpose of developing the alternative natural gas manufacturing process that, using coal as the raw material, is highly efficient as well as environmentally superior, with the fiscal 1996 results reported. A test research was carried out on the coal hydrogasification process which was selected as the optimum process based on the studies in the previous years. On the basis of the results of the studies, a free fall pyrolyzer was employed as the test equipment for the use of behavior research of hetero-elements in the test. The basic specifications were set based on a hydrogen/coal ratio of 0.2, a temperature of 950 degrees C and a pressure of 7 MPa, which are the reaction conditions of the ARCH reactor, with the basic design drafted accordingly. In a preliminary examination on the mechanisms of the coal hydrogasification reaction, analysis was made on the representative 20 different kinds of coals, on the six kinds of which studies were made on the gasification behavior using a constant heating rate pyrolyzer. As a result, from the temperature dependency of a methane forming speed, it was assumed that three components of coal had bearing upon the gasification behavior. (NEDO)

  11. Achievement report for fiscal 1981 on research under Sunshine Program. Basic research on plasma-aided coal gasification technology; 1981 nendo sushine keikaku kenkyu seika hokokusho. Sekitan no plasma gas ka gijutsu no kiso kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-03-01

    Researches are conducted for the development of a technology of producing useful gases such as acetylene, hydrogen, carbon monoxide, etc., from coal by the use of the high temperature and high-density energy of the plasma jet. In an experiment using a 100kW 3-port plasma-aided gasification unit, rapid quenching tests are conducted using hydrogen and helium, where the reaction furnace is changed, the specimen feed device is changed, and the plasma torch head is replaced by a high-power head. In a test of the coal specimen, it is found that rapid quenching exerts a great effect on the prevention of re-decomposition of the generated acetylene into hydrogen and carbon black and that a rise in the hydrogen partial pressure results in a great decrease in the quantity of acetylene generated. The said torch head replacement increases the rate of the coal specimen infiltrating into the plasma flame, which brings about an increase in the quantity of acetylene generated. It is found after all that the conventional acetylene yield of 34g/kWh increases to 59g/kWh in a rapid quenching test in which the specimen is dried Akabira coal and the plasma is an argon gas plasma containing 40% hydrogen. (NEDO)

  12. Basic investigation on promotion of joint implementation in fiscal 2000. Project for modification of Pridneprovskaya power plant in Ukraine; 2000 nendo kyodo jisshi nado kiso chosa hokokusho. Ukraine Pridneprovskaya hatsudensho kaishu jigyo keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    With objectives of saving energy and reducing greenhouse gas emission at the Pridneprovskaya power plant in Ukraine, a scrap and build project has been discussed. This project will abolish the unit No.12 among the eight units in the existing coal burning power generation facilities, and install a natural gas burning combined cycle plant comprising of three units each with an output of 100 MW. The new plant facilities will consist of gas turbines, steam turbines, HRSG and auxiliary devices, and an air-cooled synchronous power generator with a capacity of 119 MVA. Use of natural gas as fuel reduces generation of soot, sulfur oxides, nitrogen oxides, and CO. In addition, the hot effluent and waste liquor effluent will decrease from those at the present plant. The required fund will be 30,107 million yen. The energy saving effect of this project is reduction of about 7.5 million tons of crude oil equivalent as a total in 40 years. The greenhouse effect gas will decrease by about 39 million tons as a total in 40 years. The profitability estimation calls for the number of investment recovery year of 16 years, and internal profit rate of 7.32%, wherein the implementation of the project cannot be expected as a project to be carried out by private funds. (NEDO)

  13. Fiscal 1999 report on basic research for promotion of joint implementation programs. Plan for modification of Turkmenbashi cogeneration power plant; 1999 nendo Turkmenbashi netsuheikyu hatsudensho kaishu keikaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This project aims to carry out the COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change) protocol. With help of the most advanced technologies, the facilities of the above-named Turkmenian plant will be replaced by high efficiency gas turbine combined cycle power generation facilities for an increase in output (Block-1 to 220MW first and then Block-2 to 330MW 11 years later). For the 35 years following the modification, fuel consumption will be reduced by 734,632TJ or 17.24-million tons in terms of oil at a reduction rate of 42.79% and, as for greenhouse gas, CO2 gas will be reduced by 41.21-million tons at a reduction rate of 42.79%. This project and associated construction work demands 335,850-thousand US dollars in total. As for cost performance under these conditions, energy 0.051 tons in terms of oil and 0.1227 tons of greenhouse gas will be reduced for every dollar expended for modification. The FIRR (financial internal rate of return) is calculated on the basis of data collected at the site. In the absence of emission tradings over the reduced amount of CO2, FIRR is 2.51%, and, at this level, the project will be barely feasible in the presence of soft loans from, for example, the Japan Bank for International Cooperation. (NEDO)

  14. FY 1998 basic survey to promote the joint execution, etc. Plan for repair of Schekinskaya thermal power plant; 1998 nendo kyodo jisshi nado suishin kiso chosa. Schekinskaya karyoku hatsudensho kaishu keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This project is a feasibility study to get effects of reducing greenhouse effect gas by repairing Units 8, 9, and 10 (330MW in total) of Schekinskaya thermal power plant and Units 1-7 (450MW in total) of Novomoskovskaya thermal power plant. Both are very old brown coal fired thermal power plants which were constructed during 1947-1967. At present, they are run fired by natural gas. Being very superannuated, they need repair of the facilities. In the adjustment of opinions with Russia, the plan was aimed at substantial reduction of greenhouse effect gas by increasing thermal efficiency of power plant. For it, a 800MW class gas turbine combined cycle power plant is constructed at Novomoskovskaya power plant where there are existing buildings and space for equipment and where gas fuel can be used. As a result of the study, it was indicated that the reduction amount of greenhouse effect gas after the repair becomes 1,853,966 tons/yr as against 3,590,514 tons/yr before the repair. (NEDO)

  15. Fiscal 1998 research report. Development of high- efficiency electrooptic conversion compound semiconductors (21st century light project); 1998 nendo kokoritsu denko henkan kagobutsu handotai kaihatsu seika hokokusho. 21 seiki no akari keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This research aims at development of efficient lighting sources using high-brightness white LEDs. 4 research programs are as follows: (1) Basic study on emission mechanism and crystal growth, (2) Improvement of epitaxial growth methods for blue and ultraviolet LEDs, (3) Substrates for homoepitaxial growth, and (4) Basic properties of white LED lighting sources. The research results are as follows. The emission mechanism was clarified both in InGaN epitaxial layers and quantum-well structures by means of ultra-fast time-resolved spectroscopy linked with femto-second laser and the dependence of magnetic and electric fields. For reduction of a lattice defect density, an optimum thin-film crystal growth method was developed. As a new growth method of bulk single crystal substrates, a low-pressure vapor-phase growth method using radical nitrogen plasmas was developed to study synthesis of GaN and formation of single-crystal GaN. The prototype LED lighting source was prepared by using the white LEDs of 8 lm/W supplied from this project for basic study on its electric and heat radiation characteristics, and a light-guiding plate system. (NEDO)

  16. Report on the survey in fiscal 1998. Basic survey on promotion of joint project implementation (Khabarovsk thermal power plant modification plan); 1998 nendo chosa hokokusho. Kyodo jisshi nado suishin kiso chosa (Khabarovsk karyoku hatsudensho kaishu keikaku)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Discussions were given on the modification plan for Khabarovsk Thermal Power Plant as part of the basic survey on promotion of joint project implementation based on the COP3. The plan calls for shutting down the overaged power plant No. 1 (462.5 MW) and newly building the power plant No. 4 with high efficiency to reduce CO2 emission. The plant will use coal, which is mined extensively in the region. The plant will be a combined heat and power plant with a total power generation output of 576 MW and a total thermal output of 1140 Gcal/h. Effect of reducing CO2 emission as the result of this modification plan will be as much as about 1.2 million tons annually. The plant will use coal as fuel in the beginning, but if it uses natural gas in the future, for which pipeline construction from Sakhalin has been planned recently, the CO2 emission reducing effect will reach 2.4 million tons. Internal profitability was calculated with the CO2 price set at zero US dollars and with the foreign exchange rate varied, for a case of firing coal for 30 years. The profitability may vary largely according to the foreign exchange level, such as profit rate of 5.47% at 20 roubles to a US dollar, 11.04% at 12 roubles, and 21.22% at 6 roubles. The profitability should be judged somewhat low under the current exchange rate of 20 roubles to a dollar. Financial provision with a favorable condition is strongly desired. (NEDO)

  17. New Sunshine Program for Fiscal 2000. International cooperative project for developing photovoltaic power system practicalization technology (General edition); 2000 nendo New sunshine keikaku. Taiyoko hatsuden system jitsuyoka gijustu kaihatsu kokusai kyoryoku jigyo (Sogoban)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Fiscal 2000 international cooperation for the research, development, and popularization of photovoltaic power systems is compiled. In carrying out international cooperation relating to the photovoltaic power generation program of IEA (International Energy Agency), etc., officers were sent to the 15th and 16th executive committee meetings, where they deliberated on plan formulation and budget making. They also participated in the activities of Task 1: Exchange and dissemination of information on photovoltaic power systems, Task 2: Operational performance and design of photovoltaic power systems and subsystems, Task 3: Use of photovoltaic power systems in stand-alone and island applications, Task 5: Design and grid interconnection of building integrated and other dispersed photovoltaic systems, Task 7: Photovoltaic power systems in the built environment, Task 8: Study on very large scale photovoltaic power generation systems in deserts and other unexploited regions, and Task 9: Technical co-operation for photovoltaic market deployment. A discussion was made on the holding of a 4th IEA photovoltaic power system executive conference. In addition, Japan-Australia and Japan-Oman bilateral cooperative projects were implemented. (NEDO)

  18. Fiscal 1998 New Sunshine Plan auxiliary project. Report on results on development of coal hydrogasification technology (Support research); 1998 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu shien kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    R and D was conducted for the purpose of developing the alternative natural gas manufacturing process that, using coal as the raw material, is highly efficient as well as environmentally superior, with the fiscal 1998 results reported. A hydrogasification test was conducted on Taiheiyo coal at a temperature of 1,173k and a pressure of 7 MPa, which showed that all gaseous products other than methane stopped their evolution roughly in the heat-up process, while methane continued to evolve to show the highest yield. In the reactivity comparison of various types of coal, coals with carbon content of 80% or below were high in reactivity and considered suitable for hydrogasification feedstock. It was also suggested that the hydrogasification reactivity of low rank coals including sub-bituminous coals or below might be greatly affected by the presence/absence of the catalytic effects of ion-exchanged metals. Behavior experiments of sulfur and nitrogen in coal in the hydrogenation reaction were carried out using a continuous free-fall type reactor, which elucidated the effects of hydrogen pressure and gas residence time among various operational elements. (NEDO)

  19. FY 2000 report on the survey of the development of high efficiency photoelectric conversion compounds. Plan on the Light for the 21st Century; 2000 nendo kokoritsu denko henkan kagobutsu handotai kaihatsu seika hokokusho. 21 seiki no akari keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The paper described the results of the FY 2000 R and D on the Plan on the Light for the 21st Century. For the purpose of developing the white light emitting diode lighting technology, the results were obtained in the following four items: 1) basic study on the light emitting mechanism; 2) epitaxial growth in blue light/ultra violet LED and evaluation of LED characteristics; 3) substrates and characteristics for homo-epitaxial growth; 4) basic characteristics of phosphor and white light LED lighting use light source. In 1), for the purpose of clarifying the light emitting mechanism in InGaN mixed crystal semiconductor and InGaN/GaN quantum well structure, temperature dependency of time resolved light emitting spectroscopy and selective excitation light emitting spectroscopy was measured to get information/knowledge. In 2), evaluated were characteristics of multi-quantum well UV-LED composed of AlGaN/InGaN. In 3), in the GaN crystal growth by the pressure control solution growth method, studied were effects of the increasing speed of nitrogen pressure on the size of GaN monocrystal and the surface state. In 4), verified were the measuring method of quantum efficiency of three primary color phosphor materials and problems on the measured values. (NEDO)

  20. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Research on energy saving plan for NORSI Refinery); 1999 nendo NORSI seiyusho sho energy keikaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This is a feasibility study desired to connect to a joint implementation program in the future, which plans to modify the oil refining system now in existence at the NORSI Refinery in the Russian Federation. The modification plan for energy efficiency improvement consists of (1) the reconstruction of the heat exchanger network, addition of three high-efficiency heating furnaces, and the introduction of stripping steam into the pre-distillation tower for the atmospheric/vacuum distillation system, (2) the addition of two combined heat exchangers, replacement of the reboiler with a steam reboiler, and the use of reflux line in the deethanization tower for the reforming section of the catalytic reforming unit, and (3) the addition of combined heat exchangers and the installation of two high-efficiency heater furnaces for the hydrodesulfurization unit for kerosene and light oil. The plan requires 40,470,000 dollars, and will save 48,000 tons/year in terms of oil and reduce CO2 emissions by 120,000 tons/year. No settlement has been reached, however, about financing, agreement to cost performance, or apportioning of the amount of reduction in CO2 emissions to the parties involved in case of transfer under a joint implementation program. It is desired that these problems will be solved for the promotion of the project. (NEDO)

  1. FY 2000 report on the basic survey to promote Joint Implementation, etc. Survey on the repair plan for Fenchugangi fertilizer plant in Bangladesh; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Bangladesh koku Fenchugangi hiryo kojo kaishu keikaku chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of conserving energy and reducing greenhouse effect gas emission, survey was conducted for the repair plan for Fenchugangi fertilizer plant in Bangladesh. In the survey, studied were measures to increase production, measures to prolong the plant life, energy conservation measures and environmental measures. As a result of the study, it was confirmed that if the production amount targeted at first is recovered and the consumption amount of natural gas can be reduced down to the original target by rehabilitating the superannuated equipment/machines and by supplying/preparing the spare parts in shortage, the reduction in greenhouse effect gas emission is achieved and the production cost of urea fertilizer is lowered. Further, it was found that by carrying out this, energy efficiency can be heightened at the parts which can be replaced with the newest processes. The energy conservation amount calculated was 25,890 toe/y, and the amount of greenhouse effect gas reduction 60,448 t-CO2/y. The investment amount was approximately $19,106,000. The total interest is to be raised by soft loan, and the internal earning rate was 9.04% with the present prices of natural gas and urea. (NEDO)

  2. FY 1998 basic survey to promote the joint execution, etc. Overall repair plan of thermal power plants in Maritime Province of Russia; 1998 nendo kyodo jisshi nado suishin kiso chosa. Roshia Enkaishu ni okeru karyoku hatsudensho sogo kaishu keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    For thermal power plants in Maritime Province of Russia, a repair plan for effective reduction of emission of greenhouse effect gas was worked out as a draft plan for the joint execution. The project is to be implemented for the additional installation/replacement of boilers at Vladivostok No. 2 power plant, construction of a power plant as a substitute for Partizansk power plant, and new construction of Ussuriisk power plant. The draft plan includes the new installation of two gas-fired boilers/replacement of existing boilers at Vladivostok No. 2 power plant, construction of 200MW cogeneration facility at Partizansk power plant, construction of 180MW cogeneration facility at Ussuriisk power plant, abolition of small-sized boiler station, etc. The reduction amount of the greenhouse effect gas emission based on this repair plan totaled 338 million tons in project. The effect against cost is US$ 4.75 per 1 CO2 ton at Vladivostok. (NEDO)

  3. Fiscal 1998 research report (New Sunshine Project). Research on the total system for development of superconductor power application technology; 1998 nendo seika hokokusho (new sunshine keikaku). Chodendo denryoku oyo gijutsu kaihatsu total system no kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    This report summarizes the fiscal 1998 research promoted as a part of New Sunshine Project 'R and D project on development of superconductor power application technology.' This project is composed of R and D of superconductor power application technology (Rank 1), study on the total system (Rank 2), and study on review of introduction effects (Rank 3). The project is promoting R and D of the prototype superconducting generator model and elementary technologies based on the basic plan mainly by the research association. The combination test of the developed armature and the multi- cylindrical rotor model or slow response excitation rotor model was finished, and the test of the quick response excitation rotor model is in promotion. Together with R and D of hardware, this project is also promoting R and D of software through review of the introduction effects of superconducting power equipment. In fiscal 1998, the pre- final review was carried out by the project review sub- committee. 2 times of the committee, 12 times of the sub- committee, and several times of the working group were held until March, 1999. (NEDO)

  4. Achievement report for fiscal 1981 on research under Sunshine Program. Basic research on high-calorie gas production technology; 1981 nendo sunshinte keikaku kenkyu seika hokokusho. Kokarori gas seizo gijutsu no kiso kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1982-03-01

    Test and research are conducted for acquiring basic data regarding coal gasification. In the basic research for the development of a high-calorie gas production process, a small moving bed gas furnace is improved, and a high-calorie gas of a heating value of approximately 5,100kcal/m{sup 3} is stably produced at a rate of approximately 20m{sup 3} per diem. The carbon conversion rate turns out to be approximately 37% for the gas, approximately 53% for the residual char, and approximately 10% for a mixture of tar, naphthalene, benzene, phenol, etc. Hydrogen is produced making use of the residual char when a small amount of coal is added, and it is deemed that the first experiment for the development of a moving bed hydrogasification process has been successfully completed. In the study of the mechanism of hydrogasification reaction, the result of a preliminary experiment in a fixed bed pressurized gasification furnace is compared with the data from a continuous gasification experiment, and the relationship is determined between the coal feed rate and the reaction rate. Conducted besides are a basic study of problems relating to operation, basic research on a reaction mechanism (carbonization by rapid heating), estimation of the equilibrium composition of gas generated by coal gasification, etc. (NEDO)

  5. Fiscal 1999 survey report. Survey of leading countries' approaches to biomass energy development; 1999 nendo shuyokoku ni okeru biomass energy kaihatsu eno torikumi ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The survey aims to help Japan deliberate its future biomass energy development strategy including the course Japan is to follow in its research and development of biomass energy by clarifying leading countries' approaches to the subject matter and trends of their research and development efforts in this connection. The states of biomass energy development in the U.S. and Europe are reported. In the U.S., President Clinton issued Executive Order 13134 on August 12, 1999, regarding bio-based products and bioenergy development. In this country, bioenergy and bio-based production technologies have developed to reach a stage where business pays, and commercial plants are in service. The U.S. Administration mentions as a strategy the efficient development of the bioenergy industry. In Europe, where resources are versatile and local, it is difficult to assess the economy of scale, and small-scale development efforts are being accumulated. Practical technologies under development mostly involve direct combustion. European measures are similar to U.S. measures in that such political goals as local development and employment promotion are firmly woven into them. (NEDO)

  6. Expression of iNOS, eNOS, and peroxynitrite-modified proteins in experimental anti-myeloperoxidase associated crescentic glomerulonephritis

    NARCIS (Netherlands)

    Heeringa, P; van Goor, H; Moshage, H; Klok, PA; Huitema, MG; de Jager, A; Schep, AJ; Kallenberg, CGM

    Nitric oxide radicals are recognized as important mediators in various physiological and pathophysiological processes. During inflammation, increased amounts of nitric oxide (NO) are produced, but it is unclear whether NO radicals are either protective or harmful. To obtain more insight into the

  7. Study on the effect of micro-gravity on bio-functions; Seitai kino eno bisho juryoku no eikyo ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The effect of micro-gravity on bio-functions and vital reaction was studied using the facility of Underground Gravity-free Experiment Center Co. On the effect on osteoblast shape and gene expression, although fluorochrome reacting with Ca was well taken into cells, no significant difference in Ca content in cells was observed before/after falling. Expression of genes related to cell propagation was controlled under micro-gravity. Protoplast fusion of Lentinus was unaffected by micro-gravity. The mRNA fragments of gravity sensitive mutant of rice plant were affected by micro-gravity. Paramecium was set swimming in solutions with different specific gravities. The reaction behavior of Paramecium was affected by the difference in specific gravity between cell bodies and solutions. The water content metabolism functions of a mouse with needle stimulus, in particular excretory, were slightly promoted by micro- gravity. The cortisol level in blood of a falling mouse group rose showing strong stress. As the preliminary study on the geotaxis of insects, motion of bagworm was observed. 12 refs., 38 figs., 4 tabs.

  8. Application to the field of medical and welfare with fluid power; Fluid power servo no iryo fukushi bun`ya eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, Y. [Nara Technical Coll., Nara (Japan)

    1999-05-15

    Reported herein are medical and welfare apparatuses activated by fluid power servos. Reference is also made to equipment now undergoing research and development. Numerous fluid power-driven welfare and caring apparatuses have been developed, some of which are named below. In an externally powered prosthetic leg, a rocking type hydraulic servo actuator is attached on the knee section. In this device, switching is performed between an active operation in which much torque is required for instance going up and down a stairway and a passive operation in which less torque is required for instance walking on a flat place, this for increased energy efficiency. In an externally powered orthosisis, an exoskeleton is installed on the lower extremities of a patient suffering from the paralysis of both legs, and enables physical exercises for rehabilitation. Such devices are controlled by one of the two methods, the master-slave method or the manual method. Devices for the transfer of patients include an in-home bathing assist system, powered assist suit for caring, powered assist chair, movable lift for transfer, pneumatic Rubbertuator-driven rehabilitation equipment, walk training device, and wavy motion pneumatic vibrator. (NEDO)

  9. Economical effect of introducing a photovoltaic system on future electric power system; Shorai no denryoku keito eno taiyoko hatsuden system donyu ni yoru keizaiteki eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Akata, N.; Kenmoku, Y.; Sakakibara, T. [Toyohashi University of Technology, Aichi (Japan); Kawamoto, T. [Shizuoka University, Shizuoka (Japan); Nakagawa, S. [Maizuru National College of Technology, Kyoto (Japan)

    1997-11-25

    Economic impact of introduction in the future of photovoltaic power generation (PV) systems into the commercial power system is discussed from the electric utilities` point of view. In the discussion, future demand for power is predicted from the demand for power in the base year, and the optimum power source configuration corresponding to the future demand and power generation curve are worked out by use of linear programming. Then, the fixed cost and variable cost are calculated for each of the power source components, and then the expected reduction in cost per unit of power generated is calculated. As the power sources, the hydroelectric, pumped storage, oil-fired, coal-fired, LNG-fired, combined cycle, and atomic technologies are considered. The conclusion is stated below. Upon introduction of PV power equivalent to 10% of the maximum demand power, the maximum power in the service area of Chubu Electric Power Co., Inc., will be reduced by 1.23GW in 2025, and the yearly demand power by 5472GWh. Since PV lowers the peak, an increased number of power sources low in variable cost will be used although such will be low in tracking capability. An increase in power demand will enhance the cost reducing effect of the PV system. 5 refs., 4 figs., 3 tabs.

  10. Conversion of char nitrogen to N2 under incomplete combustion conditions; Fukanzen nensho jokenka ni okeru char chuchisso no N2 eno tenka

    Energy Technology Data Exchange (ETDEWEB)

    Zhuang, Q.; Yamauchi, A.; Oshima, Y.; Wu, Z.; Otsuka, Y. [Tohoku University, Sendai (Japan). Institute for Chemical Reaction Science

    1996-10-28

    The effect of combustion conditions on conversion of char nitrogen to N2 was studied in the combustion experiment of char obtained by pyrolysis of coal. Char specimen was prepared by holding ZN coal of Chinese lignite in Ar atmosphere at 1123K for one hour. A batch scale quartz-made fluidized bed reactor was used for combustion experiment. After the specimen was fluidized in reaction gas, it was rapidly heated to start combustion reaction. CO, CO2 and N2 in produced gases were online measured by gas chromatography (GC). As the experimental result, under the incomplete combustion condition where a large amount of CO was produced by consuming almost all of O2, no NOx and N2O produced from char were found, and almost all of N-containing gas was N2. At the final stage of combustion, pyridinic-N disappeared completely, and pyrrolic-N decreased, while O-containing nitrogen complexes became a main component. It was thus suggested that O-containing nitrogen complexes are playing the role of intermediate product in combustion reaction. 7 refs., 4 figs., 1 tab.

  11. Application of photo-excitation reaction on titanium oxide thin film for control of wettability; Sanka chitann hakumakujo no hikari reiki hanno no nuresei seigyo eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Watanabe, T.; Nakajima, A.; Hashimoto, K. [The Univ. of Tokyo, Tokyo (Japan); Takada, Y. [Kyushu Univ., Fukuoka (Japan)

    2000-03-31

    It is clarified that the photo-excitation hydrophilic reaction increasing wettability remarkably is induced by changing surface structure of titanium oxide radiated light. There are already many examples being in practical use of coating products applied hydrophilic reaction of titanium oxide surface such as drip-proof side millers for automobiles, self-cleaning building materials, and the like. When surface of titanium oxide having high activities for oxidisation and decomposition is coated organic materials and radiated light, wettability of surface changes as organic materials are decomposed. If it is possible to change wettability shaping pattern drastically by radiating light, the possibility of application for printing materials will be developed. After increasing contact angle by coating water and oil repellent on the titanium oxide thin film, images can be shaped by radiating light into pattern for changing surface of titanium oxide to be ultra hydrophilicity as decomposition of repellent. At that time, contact angle is 150 degree in water, 80 degree in oil, for not radiated aria, and is 0 degree in water and oil for radiated aria. Application for control technology of wettability keeps possibility of broader development to itself, not staying ability of self-cleaning and drip-proof. (NEDO)

  12. Growth hormone receptor deficiency in mice results in reduced systolic blood pressure and plasma renin, increased aortic eNOS expression, and altered cardiovascular structure and function

    DEFF Research Database (Denmark)

    Egecioglu, E; Andersson, I J; Bollano, E

    2007-01-01

    To study the role of the growth hormone receptor (GHR) in the development of cardiovascular structure and function, female GHR gene-disrupted or knockout (KO) and wild-type (WT) mice at age 18 wk were used. GHR KO mice had lower plasma renin levels (12 +/- 2 vs. 20 +/- 4 mGU/ml, P < 0.05) and inc....... These data suggest an important role for an intact GH/IGF-I axis in the maintenance of a normal cardiovascular system....

  13. Instantaneous heat flux flowing into piston top-land surface of D.I. diesel engine; DI diesel kikan no piston top land bu eno shunji netsuryusoku

    Energy Technology Data Exchange (ETDEWEB)

    Taguma, M [Zexel Corp., Tokyo (Japan); Inui, M; Enomoto, Y; Hagihara, Y [Musashi Institute of Technology, Tokyo (Japan); Koyama, T [Mitsubishi Motors Co., Tokyo (Japan)

    1997-10-01

    The thermal loads of the piston top-land surface in D.I. diesel engine during actual operation is not cleared. The authors fixed thin film thermocouples in the top-land center of a standard piston, and measured the instantaneous heat fluxes in that place. As a result, the authors made clear the thermal loads of the piston top-land surface in a cycle, and confirmed presence of the flame inflow to the piston top-land center. In addition, the authors made clear the thermal loads of the piston top-land surface in EGR operation. 4 refs., 8 figs.

  14. Inverse LMI control design method and its application to position keeping system; Gyakumondai LMI seigyokei sekkeiho no kaihatsu to ichi hoji system eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, I; Hayashi, T [Mitsubishi Heavy Industries, Ltd., Tokyo (Japan)

    1997-10-01

    Recently, with a progress of robust control such as H{infinity} control, the application of a control system design considering a robustness of controlled system fluctuation to real machinery became possible. In addition, LMI (Linear Matrix Inequality) control system design method is superior to conventional H{infinity} control, although including various difficult elements. The design algorithm permitting the robust control system design of non-linear problems by giving controlled systems was thus developed by introducing an inverse LMI control design method. This design algorithm determines the solution of models outputting the deviation between a target value and controlled variables by solving the simultaneous equations composed of a linear matrix inequality under an impulse response constraint condition and that under an H{infinity} norm constraint condition. This technique allows to give a pending step response as control condition. The technique was confirmed to be effective by its application to the position keeping control problem of marine floating structures. 6 refs., 11 figs., 2 tabs.

  15. Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress.

    Science.gov (United States)

    Bivalacqua, Trinity J; Musicki, Biljana; Hsu, Lewis L; Berkowitz, Dan E; Champion, Hunter C; Burnett, Arthur L

    2013-01-01

    Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction. We now provide scientific support for its alternative use in the management of priapism, a clinical disorder of prolonged and uncontrolled penile erection. Sildenafil administered continuously to sickle cell mice, which show a priapism phenotype, reverses oxidative/nitrosative stress effects in the penis, mainly via reversion of uncoupled endothelial nitric oxide synthase to the functional coupled state of the enzyme, which in turn corrects aberrant signaling and function of the nitric oxide/cyclic GMP/protein kinase G/phosphodiesterase type 5 cascade. Priapism tendencies in these mice are reverted partially toward normal neurostimulated erection frequencies and durations after sildenafil treatment in association with normalized cyclic GMP concentration, protein kinase G activity and phosphodiesterase type 5 activity in the penis. Thus, sildenafil exerts pleiotropic effects in the penis that extend to diverse erection disorders.

  16. Study on low permeable backfill materials. Backfill materials for waste disposal facilities; Koshisuisei juten zairyo ni kansuru kenkyu. Hoshasei haikibutsu shobun shisetsu eno tekiyosei kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Shiraishi, F; Konishi, M; Shiraishi, H [Okumura Corp., Osaka (Japan)

    1994-11-15

    A discussion was given on the fundamental properties of mortar made from cement mixed with silica fume. Four kinds of silica fumes with different particle size distributions were used. The following results were obtained: distribution of pores in mortar admixed with silica fume shifts to the smaller radius side; while the admixture increases the compression strength in mortar, the increasing trend varies depending on the kinds of silica fumes; this is thought to be caused from the difference in pozzolan activity between silica fumes; and the strength increase is caused by densification of the structure due to the pozzolan reaction that is generated after hydration, or in other words, decrease in the pore volume. The applicability of the mortar was investigated as a filling mortar to fill up clearances between wastes. It was found that the filling performance can be controlled by mixing silica fume at an adequate level and adjusting the viscosity. The diffusion coefficient for the admixed concrete is smaller by 30% to one digit than that for the ordinary concrete. High-performance water stopping concrete of 0.11 {times} 10{sup 4}cm {sup 2}/s at maximum was obtained. The concrete can be regarded as a material having superb filling and water stopping performances. 6 refs., 4 figs., 5 tabs.

  17. Application of photovoltaic generating system to electric power in large ship; Taiyoko hatsuden system no ogata senpaku eno oyo ni kansuru kento

    Energy Technology Data Exchange (ETDEWEB)

    Katagi, T; Ogawa, S; Nishikawa, E; Hashimoto, T [Kobe University of Mercantile Marine, Kobe (Japan); Ishida, K

    1996-10-27

    This paper describes the design of electric power system in a ship with photovoltaic power generating system, to examine applicability of the photovoltaic power generating system to the inboard power source. It also discusses effectiveness of the system for sea environment. At first, the actual route of a car carrier, meteorological data, and quantity of power consumption were picked up from the deck logbook and engine logbook. Then, the installation area of photovoltaic arrays, the quantity of photovoltaic power generation derived from the quantity of solar radiation, and the capacities of batteries and inverters were calculated, to design the electric power system in the ship with photovoltaic power generation system. Moreover, the NOx and SOx emissions were compared between the present power system and the usual power system using diesel power generator, to discuss the effectiveness of the present system for sea environment. Consequently, it was found that the emission of NOx was reduced by about 33% and the emission of SOx was reduced by about 28% compared to the usual power system. The effectiveness for sea environment was confirmed. 9 refs., 5 figs., 4 tabs.

  18. Economic development in India and the effect on the energy market in Asia; Indo no keizai hatten to Asia no energy shijo eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    As for the real GDP growth rate in India, the real GDP per capita during 1980-1993 increased 2.9% on annual average, but that in China did 8.0%. India has largely been behind China in the economic growth, but since the liberalization of economy in 1991, the Indian economy has remarkably been developed. It is predicted that the real GDP during 1993-2010 will be 5-6% on annual average. The difference in GDP increase between India and China is caused by differences in energy conservation, speed of conversion from non-commercial energy to commercial energy, serviceability of the industrial structure, etc. It is predicted that the primary energy consumption will grow on the level of China. The oil demand will grow 4-6% in China and 5-6% in India in 1993-2010, showing more increase in India. For oil import to India to exceed 1 million B/D in 2000, it is necessary to clear the ceiling of the international balance. For India to become a big country corresponding to its population size, a lot of difficulties should be overcome. 49 refs., 104 figs., 62 tabs.

  19. Management in ekonomija: ali je to dvoje ali eno? (Elementi in razumevanje postocializma in managerske revolucije = Management and Economy: Are They the Same Or Not?

    Directory of Open Access Journals (Sweden)

    Tonci Kuzmanic

    2007-03-01

    Full Text Available Author starts from important but suppressed equalisation of economy and management in post socialist and post capitalist circumstances which represents the very essence of post-modern global dominance (globalisation. An attempt to distinguish economy from management is connected with the appearance of neo-liberalism as the central argumentative machinery of management being connected with postmodern type of subjectivity. In comparison with the so-called »objective law« around which economy used to revolve (ideally, of course, management explicitly leaves this terrain and opens itself up to the subjective, even subversive activity at the level of global society. In that sense economy and management are operating on two radically different levels and we could even speak of two different entities which should be analytically distinguished. The very supposition for modern defence with regard to post-modern forms of dominance is exactly a possibility of differentiating between economy and management.

  20. ANALYSIS OF ACE, ACTN3, ENOS, PPARG, PPARA, HIF-15, PPARGC1B GENE POLYMORPHISMS FOR DETERMINATION A GENETIC PREDISPOSITION TO A VARIETY OF SPORTS

    Directory of Open Access Journals (Sweden)

    S. B. Drozdovska

    2013-05-01

    Full Text Available To establishing the possibility of assessing genetic iinherited predisposition to various sports, the differences in the distribution of genotypes of the complex polymorphisms in groups of athletes, specializing in sports with different types of energy supply of muscular work were studied. The paper examined the DNA 332 persons, of which 110 athletes involved in speed- power sports, 85 - in endurance sports , 51 - in sports that require a combination of strength and endurance, 86 - with no experience regular exercise.

  1. Field experiment for investigation of very shallow basement structure by micro-gravity survey; Microgravity tansa no gokusenbu kiban chosa eno tekiyo jikken

    Energy Technology Data Exchange (ETDEWEB)

    Oshita, K; Nozaki, K [OYO Corp., Tokyo (Japan)

    1997-10-22

    This paper illustrates the field experiment results in which micro-gravity survey was applied to investigation of very shallow basement structure between a few m and 10 m. Its applicability was discussed. In principle, the micro-gravity survey was conducted at the measuring points in a grid with 20 m pitch. Measuring points of 174 were used. The gravity system used for the measurements is an automatic gravimeter CG-3M made by the Scintrex. Survey results of P-wave reflection method conducted at the site using a vibrator focus were used as control data of micro-gravity survey. Consequently, change in the thickness of surface layer (earth filling) shallower than the depth of -10 m could be grasped as a plane. It was found that the micro-gravity survey is a useful method for the investigation of very shallow basement structure. Survey results by the reflection method could contribute to the determination of trend face at filtration and construction of density model as well as the geologic interpretation of gravity anomaly. As a result, reliability of micro-gravity survey and reflection method could be enhanced, mutually. 3 refs., 8 figs.

  2. Study on application of radar technique to explore mineral resources. 1. Sample test in laboratory; Radar ho no kosho tansa eno tekiyosei kento. 1. Shitsunai shiryo shiken

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, A; Okada, K [Sumitomo Metal Mining Co. Ltd., Tokyo (Japan); Arai, E [Metal Mining Agency of Japan, Tokyo (Japan); Noguchi, K; Fujiwara, K [Waseda University, Tokyo (Japan)

    1997-10-22

    Dielectric constants of ore body and mother rock specimens taken from an epithermal gold deposit were measured in the frequency band of radar technique. Applicability of the radar technique to mineral exploration has been investigated by comparing measured results and ore showing. This paper describes the results. Measured results of the dielectric constants are summarized as follows. The specific dielectric constant in the forced dry condition did not depend on specimens. The specific dielectric constant in the water saturated condition increased with increasing the porosity. The conductivity increased with increasing the specific dielectric constant. The specific dielectric constant and conductivity increased with increasing the water content. The specific dielectric constant did not depend on types of rocks. The specific dielectric constant decreased with increasing the frequency. Difference of the specific dielectric constant in the water saturated condition decreased with increasing the frequency. The radar technique was applied to blind deposits. Since they were often in the ground water saturated zones, it was considered that the reflection at the boundary was enhanced with increasing the difference of specific dielectric constant between ore body and mother rock compared with that in unsaturated zones. 8 refs., 8 figs., 3 tabs.

  3. Simulation of emergency evacuation behaviour during disaster by using distinct element method; Hisaiji no gunshu hinan kodo simulation eno kobetsu yosoho no tekiyo ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Kiyono, J.; Miura, F.; Takimoto, K. [Yamaguchi Univ., Yamaguchi (Japan). Faculty of Engineering

    1996-04-21

    In this study, the possibility to apply the Distinct Element Method (DEM) to human evacuation behavior during a disaster was investigated, evacuation from rooms to outside though a passage or steps and a jam were examined as a basic consideration. The main results were obtained as follows: according to an analysis of evacuation behavior when elements of DEM were substituted for individual humans, the trace of individual people and force acting there to and the trace of the whole group so every time can be understood, analysis can also be conducted from local to macro. In the DEM analysis, a mutual distance between people and characteristics of behavior can be expressed well by introducing an imaginary bane into the elements. Evacuation time due to change of space shape can be compared and time series change of force acting on individual people can be understood according to the investigation on evacuation time difference due to shape change at the exit and entrance and the jam caused by the arch effect happened when the crowed flow appeared at the exit and entrance. 16 refs., 21 figs., 4 tabs.

  4. Sildenafil citrate-restored eNOS and PDE5 regulation in sickle cell mouse penis prevents priapism via control of oxidative/nitrosative stress.

    Directory of Open Access Journals (Sweden)

    Trinity J Bivalacqua

    Full Text Available Sildenafil citrate revolutionized the practice of sexual medicine upon its federal regulatory agency approval approximately 15 years ago as the prototypical phosphodiesterase type 5 inhibitor indicated for the treatment of male erectile dysfunction. We now provide scientific support for its alternative use in the management of priapism, a clinical disorder of prolonged and uncontrolled penile erection. Sildenafil administered continuously to sickle cell mice, which show a priapism phenotype, reverses oxidative/nitrosative stress effects in the penis, mainly via reversion of uncoupled endothelial nitric oxide synthase to the functional coupled state of the enzyme, which in turn corrects aberrant signaling and function of the nitric oxide/cyclic GMP/protein kinase G/phosphodiesterase type 5 cascade. Priapism tendencies in these mice are reverted partially toward normal neurostimulated erection frequencies and durations after sildenafil treatment in association with normalized cyclic GMP concentration, protein kinase G activity and phosphodiesterase type 5 activity in the penis. Thus, sildenafil exerts pleiotropic effects in the penis that extend to diverse erection disorders.

  5. Sočutno starševstvo in vzgojni stili v eno- in dvostarševski družini

    OpenAIRE

    Novak, Petra; Urh, Katarina; Presker, Martina

    2018-01-01

    Vzgoja otroka je ena izmed najtežjih vsebin življenja, v katero so starši neposredno vpleteni v procesu svojega delovanja. Otrok se rodi v že ustaljen sistem, ki si ga zakonca oziroma partnerja ustvarita še pred rojstvom otroka. Z vsakim novorojenim otrokom je treba vzpostaviti novo družinsko ravnovesje, da se bo družina lahko razvijala naprej. Pri razvoju otroka v družini ima najpomembnejšo vlogo odnos, ki ga starša vzpostavita z njim takoj ob njegovem rojstvu. Enako pomembno je tudi čustven...

  6. Všeobecný přenos daňové povinnosti jako krok k zásadní modernizaci DPH

    OpenAIRE

    Kohoutková, Růžena

    2014-01-01

    This final thesis deals with introduction of reverse charge mechanism of value added tax. The current system of value added tax has weaknesses, including carousel fraud, negative impact on cash flow of businesses and complicated rules to collect and manage the tax. Reverse charge mechanism is considered as a solution of existing weaknesses of current system. Although this regime is able to solve the mentioned weaknesses, it also has some disadvantages. Especially, it is a negative impact on c...

  7. Material revolution, and analysis of its impacts on the industry and technology of the next generation; Zairyo kakumei to jisedai sangyo gijutsu eno impact bunseki

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1984-03-01

    This paper discusses possibility of advanced materials from seeds and expectations from needs; and also describes consistency between the seeds and needs, and possible impacts of these materials on the industry and technology of the next generation. Chapter 1 presents the promising results and eventual possibilities, based on the basic studies, of the advanced materials, e.g., fine ceramics, highly functional polymers, new alloys and composite materials. Chapter 2 analyzes the properties and functions attainable by these materials, and expected applicable areas; investigates their technical and economical possibilities; and also investigates their ripple effects on the technology and economy. Chapter 3 investigates the current situations of the demands in the automobile, chemical plant and energy areas, and problems involved in development of these materials for these areas. Chapter 4 investigates the measures to promote consistency between the seeds and needs of these materials, and impacts of these advanced materials on the related techniques, related industries and industrial structures. Chapter 5 summarizes the problems and measures narrowed down in Chapters 1 to 4 comprehensively for the above areas; and the measures to be taken by the private sector, and cooperation by the industrial, government and academic circles. (NEDO)

  8. In Vitro Activation of eNOS by Mangifera indica (Careless™) and Determination of an Effective Dosage in a Randomized, Double-Blind, Human Pilot Study on Microcirculation.

    Science.gov (United States)

    Gerstgrasser, Alexandra; Röchter, Sigrid; Dressler, Dirk; Schön, Christiane; Reule, Claudia; Buchwald-Werner, Sybille

    2016-03-01

    Mangifera indica fruit preparation (Careless™) activates the evolutionary conserved metabolic sensors sirtuin 1 and adenosine monophosphate-activated protein kinase, which have been identified as playing a key role in microcirculation and endothelial function. Here, an acute effect of a single dose of 100 mg or 300 mg Careless™ on microcirculation was investigated in a randomized, double-blind, crossover pilot study in ten healthy women to determine the effective dosage. Microcirculation and endothelial function were assessed by the Oxygen-to-see system and pulse amplitude tonometry (EndoPAT™), respectively. Cutaneous blood flow was increased over time by 100 mg (54% over pre-values, p = 0.0157) and 300 mg (35% over pre-value, p = 0.209) Careless™. The EndoPAT™ reactive hyperemia response was slightly improved 3 h after intake compared to pretesting with 300 mg Careless™. Furthermore, activation of endothelial nitric oxide synthase, as an important regulator for endothelial function, was tested in vitro in primary human umbilical vein endothelial cells. Careless™, after simulation of digestion, increased the activated form of endothelial nitric oxide synthase dose-dependently by 23% (300 µg/mL), 42% (1500 µg/mL), and 60% (3000 µg/mL) compared to the untreated control. In conclusion, the study suggests moderate beneficial effects of Careless™ on microcirculation, which is at least partly mediated by endothelial nitric oxide synthase activation. Georg Thieme Verlag KG Stuttgart · New York.

  9. Effects of fuel properties and oxidation catalyst on diesel exhaust emissions; Keiyu seijo oyobi sanka shokubai no diesel haishutsu gas eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, S; Morihisa, H; Tamanouchi, M; Araki, H; Yamada, S [Petroleum Energy Center, Advanced Technology and Research Institute, Tokyo (Japan)

    1997-10-01

    Effects of fuel properties (T90 and Poly-Aromatic Hydrocarbons: PAH) and oxidation catalyst on diesel exhaust emissions were studied using three DI diesel engines and two diesel passenger cars. (IDI engine) PM emissions were found to increase as T90 and PAH increased and could be decreased considerably for each fuel if an oxidation catalyst was installed. 5 refs., 9 figs., 3 tabs.

  10. Simple method for thick blade calculation. Part 2. Application to a thin blade; Kanbenna ichiatsuyoku keisanho (zokuho). Usui tsubasa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Maita, S; Ando, J; Nakatake, K [Kyushu University, Fukuoka (Japan). Faculty of Engineering

    1996-04-10

    A source and QCM (SQCM) method has been developed, by which the blade performance can be calculated in a short time with satisfying the Kutta`s condition without repeating calculations even for the three-dimensional blade. Performances were calculated for the two-dimensional and three-dimensional blades. The SQCM has provided appropriate results. However, it was found that there are some problems for thin blades. In this study, the SQCM has been applied to a thin blade. The conventional eddy model equation of SQCM is not a continuous distribution in the strict sense. In this study, this problem has been modified. When point eddies with constant strength are in line continuously within the interval, the induced velocity at an arbitrary position can be expressed by the integral equation using a position of marginal point of the interval. This equation can be analyzed by the integral of influence coefficient. The position of marginal point of the interval is a position of control point determined by the QCM theory. As a result of the modification, it was found that the SQCM in response to a thin blade has provided precise calculation results stably even for an ultra thin blade with the blade thickness ratio of 0.001. 1 ref., 8 figs.

  11. Application of vertical electrical sounding combined with induced polarization method in ground water exploration; IP koka wo koryoshita hiteikoho suichoku tansa no chikasui chosa eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kondo, M; Sakurada, H [Sumiko Consultants Co. Ltd., Tokyo (Japan); Suzuki, T [Hokkaido Development Bureau, Hokkaido Development Agency, Sapporo (Japan)

    1996-10-01

    For ground water exploration using vertical Schlumberger exploration method, measurement and analysis combined with induced polarization (IP) effect were conducted as trial. For the Schlumberger method, potential is measured at the center between potential electrodes during flow of dc current between current electrodes. In the case of vertical exploration, measurements are repeated with fixed potential electrodes by extending the distance between current electrodes. Ground water exploration was conducted using this method at Otaki village, Hokkaido. Geology of surveyed plateau consists of a basement of Pliocene tuffs and Quaternary Pleistocene sediments covering on the surface. For the results of analysis, four to seven beds were detected from the resistivity. The depth up to the lowest bed was between 25 and 85 m, the resistivity of each bed was between 9 and 8,000 ohm{times}m, and the polarizability was between 1 and 15 mV/V. Among these resistivity zones, it was judged that zones satisfying following three conditions correspond to coarse grain sediments saturated with ground water, and can be expected as aquifers; having resistivity ranging between 100 and 1,000 ohm{times}m, polarizability higher than 10 mV/V, and relatively large thickness. 11 refs., 6 figs.

  12. Three dimensional transient electromagnetic model study for fracture prediction from tunnel face; Sanjigen model keisan ni yoru TEM ho no tunnel zenpo tansa eno tekiyosei no kento

    Energy Technology Data Exchange (ETDEWEB)

    Wada, K; Tsutsui, T; Saito, A [Mitsui Mineral Development Engineering Co. Ltd., Tokyo (Japan); Hara, T [Toda Corp., Tokyo, (Japan); Zhdanov, M [University of Utah, UT (United States)

    1996-10-01

    In order to apply TEM model to fracture prediction at tunnel face, 3-D TEM model computation by FEM was conducted by installing a transmission loop on a tunnel face. MT field responses diffusing into the 3-D model were computed by time-domain difference calculus, and analytical precision was improved by introducing a staggered grid method. In the case where a low resistive zone exists before a tunnel face, time variance in diffused eddy current and induction current in the low resistive zone could be obtained. The difference in tunnel-axial transient curve (transient phenomenon curve in magnetic field) between uniform medium and low resistive zone models was based on the absorption process of diffused eddy current into the low resistive zone, and the expanding process of it toward the outside. Change in background condition could be predicted from the background and the ratio of transient curves every measurement. The detection limit of the low resistive zone was dependent on resistivity contrast, distance and geometry. Fluctuation in measurement due to noises and S/N ratio were also essential. 3 refs., 10 figs.

  13. Can spatial autocorrelation method be applied to arbitrary array shape; Kukan jiko sokanho no nin`i array eno tekiyo kanosei

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, H; Iwamoto, K; Saito, T; Tachibana, M [Iwate University, Iwate (Japan). Faculty of Engineering

    1997-05-27

    Methods to learn underground structures by utilizing the dispersion phenomenon of surface waves contained in microtremors include the frequency-wave number analysis method (the F-K method) and the spatial autocorrelation method (the SAC method). Despite the fact that the SAC method is capable of exploring structures at greater depths, the method is not utilized because of its stringent restriction in arrangement of seismometers during observation that they must be arranged evenly on the same circumference. In order to eliminate this restriction in the SAC method, a research group in the Hokuriku University has proposed an expanded spatial autocorrelation (ESAC) method. Using the concept of the ESAC method as its base, a method was realized to improve phase velocity estimation by making a simulation on an array shifted to the radius direction. As a result of the discussion, it was found that the proposed improvement method can be applied to places where waves come from a number of directions, such as urban areas. If the improvement method can be applied, the spatial autocorrelation function needs not be even in the circumferential direction. In other words, the SAC method can be applied to arbitrary arrays. 1 ref., 7 figs.

  14. Passive leg movement enhances interstitial VEGF protein, endothelial cell proliferation, and eNOS mRNA content in human skeletal muscle

    DEFF Research Database (Denmark)

    Hellsten, Ylva; Rufener, Nora; Nielsen, Jens J

    2008-01-01

    .05) in blood flow without a significant enhancement in oxygen uptake. Muscle interstitial fluid was sampled with microdialysis technique and analyzed for vascular endothelial growth factor (VEGF) protein and for the effect on endothelial cell proliferation. Biopsies obtained from the musculus vastus lateralis...... to cultured endothelial cells revealed that dialysate obtained during leg movement induced a 3.2-fold higher proliferation rate (P level fourfold above resting levels. VEGF mRNA and MMP-2 mRNA levels were...

  15. Utilization of hot exhaust water from power station to marine cultivation to increase product. Hatsudensho onhaisui no suisan zoyoshoku eno riyo

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, K [The University of Tokyo, Tokyo (Japan). Faculty of Agriculture

    1990-07-20

    A large quantity of waste sea water, exhausted after having been used as cooling water in the thermal and unclear power stations, is higher by about 7 centigrade in temperature than that when taken in. Its utilization to the marine cultivation to increase product was explained in present status and points of problem. Among aquatic animals to like high temperature, those, valuavle from the viewpoint of fishery, are bred in different places. Upon breeding spawn to fry young fish, there are two methods of using it, ie., as species to be cultivated or let go in the water flow, and for the production of edible fish, high in price, such as sea bream, yellowtail and lobster. In any case, hot exhaust water gives effect of having fish quickly grow, and stimulating spawn and fry young fish in sexual ripeness. For example, ear shell and prawn are 5 to 6 times in elongation of shell length and 9 times even in weight, respectively, as large as those in case of natural sea water. While there are problems in costing required for pumping hot exhaust water up in the cultivation on land, and temperature adjustment in summer and winter, and water quality control in the crawl cultivation at the water takeout, which must be going to be solved for the commercialization and industrialization. 10 figs., 1 tab.

  16. Application of adaptive control to windmill power system by computer simulation. Simulation ni yoru tekio seigyo no furyoku hatsuden system eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Tomiya, T.; Matsuo, T. (Anan College of Technology, Tokushima (Japan)); Suzuki, T.; Kamano, T. (Tokushima University, Tokushima (Japan). Faculty of Engineering)

    1991-07-20

    A windmill power system using load DC generators having resistive load was subjected to discussions by simulation on development of a control method and its output characteristics to draw out the wind energy effectively even when the system characteristics are unknown. The control method used is a mountaineering method available among adaptive control methods. As a result of discussions, the effectiveness of the mountaineering method was confirmed in controlling the output either when the wind velocity is constant or variable. With respect to the control interval, which is a problem in carrying out a control, it was found that the control output stabilizes as the control interval is increased when the wind velocity is constant, but takes longer time before reaching a steady state output. When the wind velocity is variable, the increased control interval reduces the output slightly because of the load resistance change becoming coarser. It was also revealed that, on simulated natural winds, this control method can draw out more energy than by a fixed load resistance. 7 refs., 11 figs., 1 tab.

  17. Genetic algorithm based on virus theory of evolution for traveling salesman problem; Virus shinkaron ni motozuku identeki algorithm no junkai salesman mondai eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Kubota, N. [Osaka Inst. of Technology, Osaka (Japan); Fukuda, T. [Nagoya University, Nagoya (Japan)

    1998-05-31

    This paper deals with virus evolutionary genetic algorithm. The genetic algorithms (GAs) have been demonstrated its effectiveness in optimization problems in these days. In general, the GAs simulate the survival of fittest by natural selection and the heredity of the Darwin`s theory of evolution. However, some types of evolutionary hypotheses such as neutral theory of molecular evolution, Imanishi`s evolutionary theory, serial symbiosis theory, and virus theory of evolution, have been proposed in addition to the Darwinism. Virus theory of evolution is based on the view that the virus transduction is a key mechanism for transporting segments of DNA across species. This paper proposes genetic algorithm based on the virus theory of evolution (VE-GA), which has two types of populations: host population and virus population. The VE-GA is composed of genetic operators and virus operators such as reverse transcription and incorporation. The reverse transcription operator transcribes virus genes on the chromosome of host individual and the incorporation operator creates new genotype of virus from host individual. These operators by virus population make it possible to transmit segment of DNA between individuals in the host population. Therefore, the VE-GA realizes not only vertical but also horizontal propagation of genetic information. Further, the VE-GA is applied to the traveling salesman problem in order to show the effectiveness. 20 refs., 10 figs., 3 tabs.

  18. FY 2000 report on the survey of strategies for spreading renewable energy to developing countries; 2000 nendo tojokoku eno saisei kano energy fukyu senryaku chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For Laos, Bangladesh, Malaysia and Vietnam, survey was conducted to promote the introduction and spread of renewable energy, mainly the photovoltaic power generation. Relating to the solar radiation, the amount in the four countries is much higher than that in Japan, 3.4kWh/m{sup 2}/day on average. The countries are areas suitable for the photovoltaic power generation. As to the wind velocity, the area where the wind velocity is higher than 5m/second, which enables the introduction of the wind power generation, is limited to the south/west of Bangladesh, Malaysia, and the coastal part and islands in Vietnam. The wind power generation is being used in Malaysia and Vietnam. As for the precipitation, it rains concentratedly in the rainy season, and therefore, it is difficult to stably secure energy through the year by the small-scale hydroelectric power generation. In Vietnam, however, resident individuals eagerly introduce the small-scale hydroelectric power generation, and about 20,000kW is now in operation. Concerning the introduction of the photovoltaic power generation, Bangladesh is in a state of working out a master plan, Laos is in a state of drawing up a plan for the spread, and Malaysia and Vietnam are in a state of the verification. (NEDO)

  19. Fundamental study on PV system for floating water power device `Mighty Whale`; Okiai futaishiki haryoku sochi `Mighty Whale` eno taiyoko hatsuden sochi tosai no kihon kento

    Energy Technology Data Exchange (ETDEWEB)

    Washio, Y [Japan Marine Science and Technology Center, Kanagawa (Japan)

    1996-10-27

    Studied in this paper is the use of a photovoltaic power generation system in combination with a wave energy conversion system to cover the latter`s weak point that it is available but intermittently. An offshore floating wave power device Mighty Whale (MW) is described, which will have a wave energy absorbing air chamber in the front and an anti-rocking float that looks like a whale in the rear. The movement, up and down and back and forth, of the water surface in the air chamber due to incident waves turns the power generator turbine. Out of the space available on the MW, a 200m{sup 2} area has been specified as the place suitable for the installation of solar cells capable of a maximum output of 20kW, for which specification the elevation of the sun has been taken into account. Batteries will routinely be supplied with power in parallel from the wave activated and photovoltaic devices, the supply will be limited when the batteries are fully charged, and an auxiliary power generator will be run in case of shortage. Power that can be provided by a 20kW solar array was calculated using actual data of sunshine on the slope for each array orientation, and required battery capacity was calculated for each solar array orientation. Important items for consideration for the insurance of reliability on the ocean include measures against salt damage, detailed designing of wiring, and coordinated operation of photovoltaic and wave activated power generation systems. 3 refs., 6 figs., 5 tabs.

  20. Thermal sensation vote simulation on the aged for bus air conditioning; Koreisha wo koryoshita onkan suchi simulation no bus kucho eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Takeuchi, H; Nishijima, H; Kitada, M; Shinma, A [Denso Corp., Aichi (Japan)

    1997-10-01

    The Numbers of passengers on the aged of sight-seeing buses about 5 times bigger than those of car passengers, have been increasing gradually. The former paper of DENSO in 1994 introduces quantitative method, which simulates passenger heat amount given by sun light at various solar positions. At this time, this paper introduces quantitative method, which simulates passengers thermal sensation skin temperature and also heat amount given by sun light at various solar positions. 5 refs., 8 figs., 2 tabs.

  1. Psychological influences for the driver by the changes of running circumstance; Jidosha no soko kankyo henka no driver eno shinriteki eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Okura, S; Yokomori, M; Yamaguchi, S [Meijo University, Nagoya (Japan)

    1997-10-01

    A driver is influenced psychologically by the cars proceeding on the street and the cars parked on the shoulder which come into the front view. The traffic accidents are caused when these influences put a lot of stress on a driver. In this report, we study the relations between the road traffic condition on the streets and the highway and the driver`s psychological and psysiological responses by using the driver`s front view, sweating and pulse rate. 6 refs., 8 figs.

  2. Estrogen and phytoestrogens: Effect on eNOS expression and in vitro vasodilation in cerebral arteries in ovariectomized Watanabe heritable hyperlipidemic rabbits

    DEFF Research Database (Denmark)

    Lund, Claus Otto; Mortensen, A; Nilas, Lisbeth

    2007-01-01

    -six female ovariectomized Watanabe heritable hyperlipidemic (WHHL) rabbits were randomised to treatment with 17beta-estradiol (17beta-E(2)), SoyLife 150 or control for 16 weeks. Ring segments of basilar artery (BA) and posterior cerebral artery (PCA) were mounted in myographs for isometric tension recordings...

  3. Recent progress in 'bioelectronics' research. Part 4. ; Recent trends in biosensor research and development. Baioerekutoronikusu eno michi (shorai wa saibogu mo). 4. ; Baiosensa gijutsu saizensen

    Energy Technology Data Exchange (ETDEWEB)

    Karube, I. (The Univ. of Tokyo, Tokyo (Japan). Research Center for Advanced Science and Technology)

    1994-02-20

    Biosensors are structured basing on a variety of principles. The latest trend of the research and development of biosensors is introduced to explain how the five senses such as taste sense and olfactory sense are detected. A biosensor is structured by combining biological element with a transducer which converts the result measured by the said element into electrical signal. Enzyme is most widely used at present. The enzyme recognizes a chemical substance very closely, and has a feature of promoting its reaction only. Chemical substances, therefore, can be distinguished if this enzyme is used. The principle of the biosensor is explained quoting the enzyme sensor as an example. Immune reaction and microbe reaction can be monitored by the similar principle to the above-mentioned principle. Sensors for measuring substances which are the bases of taste have been developed. Studies on smell sensors are also actively carried on, and the quartz oscillator is used mainly. 4 refs., 4 figs.

  4. Advancing aging society and its effect on the residential use energy demand; Shintensuru koreika shakai to kateiyo energy juyo eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    The paper analyzed various factors regulating the energy demand in aged households and viewed the future residential use energy demand in the aging society. In Part 1, based on the family budget survey annual report, a study was made of the energy consumption situation of aged people and the trend of the future residential energy consumption. In Part 2, a study was conducted based on survey data on the U.K., France, Sweden and Denmark. In Western countries which are the developed countries of aging, the energy conservation policy effectively worked for the space heating demand which is highest of all, and factors of the energy consumption increase by aging were absorbed. However, since in Japan, aging is rapidly advancing and further there are relatively more factors which connect to an increase in energy consumption in aged households as compared with Western countries, it is thought that Japan is in a situation where the energy consumption increases more often, influenced by aged households. 91 refs., 130 figs., 41 tabs.

  5. FY 1990 achievement report on the survey of possibility of introducing solar energy into buildings; 1990 nendo taiyo energy no kenchikubutsu eno donyu kanosei chosa seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    This paper describes the achievements in fiscal 1990 on survey on possibility of introducing solar energy into buildings. Capacity of photovoltaic power generation facilities installed on an area of 1600 km{sup 2}, such as roofs of residential houses, schools and building may be calculated on a trial bases as 100 million kW at maximum. The capacity can replace 16% of the total demand and corresponds to 26.30 million kiloliters (9%) as converted to crude oil. If photovoltaic power generation is utilized on buildings of users, diversified technological criteria are required from the viewpoint of legislation covering wide range of architectural, electrical and disaster aspects. However, no direct and clear standards are available now, except for the electric power business law. What are urgently required are solar cell standardization, incentive subsidies, aging safety, institutions for electric power sale and purchase, and establishment of technological criteria. An utilization example survey revealed problems in array installation and size. Increased demand, mass production and cost reduction will create a favorable cycle. Introduction, proliferation, and acceleration under policies at public facilities which are expected of enlightenment and development into other areas will be the effective means for the purpose. (NEDO)

  6. Application of super workable concrete to main tower of cable-stayed prestressed concrete bridge. ; Kiba park grand bridge. PC shachokyo no shuto eno tekiyo. ; Kiba koen ohashi

    Energy Technology Data Exchange (ETDEWEB)

    Matsuoka, Y.; Shindo, T.; Sakamoto, A. (Taisei Corp., Tokyo (Japan))

    1993-08-01

    The Kiba Park Grand Bridge is a cable-stayed prestressed concrete (PC) bridge with a length of 186m. The main tower of this PC cable-stayed bridge consists of a pair of vertical columns with height of 60m and a beam connecting the columns. For the purpose of the advanced efficiency of construction without formwork and removal work and the improvement of durability, the precast buried formwork made of polymer impregnated concrete formwork was adopted. Approximate 650 cubic meter of super workable concrete was placed for the upper part ranging from 7th to 17th blocks of vertical columns and the beam. Blast furnace cement B and fly ash were used as binder. Naphthalenesulfonic acid type high performance water reducing agent and lignosulfonic acid type AE (air-entraining) water reducing agent were used as admixtures. Super workable concrete was mixed using forced double-axle mixers in the ready-mixed concrete plant. Satisfactory quality of the fresh concrete and strength of the hardened concrete were obtained. 2 refs., 11 figs., 3 tabs.

  7. Progress of admixtures and quality of concrete. 2. ; Approaches to ultra-high-strength concrete. Konwa zairyo no shinpo to concrete no hinshitsu. 2. ; Chokokyodo concrete eno approach

    Energy Technology Data Exchange (ETDEWEB)

    Kawai, T. (Shimizu Construction Co. Ltd., Tokyo (Japan)); Abe, M. (Building Research Institute, Tsukuba (Japan))

    1994-02-15

    Ultra-high-strength concrete of 600 kgf/cm[sup 2] or more is reviewed. MDF (macro defect free) cement, spheroidal cement and mechanically stabilized cement have been developed for ultra-high-strength concrete, however, in general, DSP (densified system containing homogeneously arranged ultra-fine particles) technique is now usual in which a water-cement ratio is reduced by use of advanced air entraining and water reducing agents and cured concrete is densified by use of ultra-fine particles as admixture. Four kinds of substances such as naphthalene system and polycarboxylic acid system are used as air entraining and water reducing agents, and silica fume is used as ultra-fine particle admixture which can be effectively replaced with blast furnace slag or fly ash. Various use examples of ultra-high-strength concrete such as an ocean platform are found in the world, however, only some examples such as a PC truss bridge and the main tower of a PC cable stayed bridge in Japan. 22 refs., 10 figs., 2 tabs.

  8. Deposition of calcium carbonate into postglacial reefs: a test on a 'coral reef hypothesis'. Kohyoki no sangosho eno tansan calcium taiseki sokudo

    Energy Technology Data Exchange (ETDEWEB)

    Kayanne, H [Geological Survey of Japan, Tsukuba (Japan)

    1993-06-15

    This paper describes the following matters on changes in rates of deposition of calcium carbonate into postglacial coral reefs: Estimation was made on change in CaCO3 deposition in four coral reefs the data of which relating to all cross sections down to reef base have been acquired by drilling; the main deposition periods in the coral reefs formed in the postglacial period were five to six thousand years ago; the maximum deposition rate is estimated to be 2.7 [times] 10[sup 14] gC per one thousand years under an assumption that the total deposition amount in postglacial coral reefs is 1.2 [times] 10[sup 18] gC (converted to carbon amount); the recent deposition rate is (1/7.5) that of the former rate; from information obtained on submerged coral reefs, deposition amounts in coral reefs before 10,000 years ago are judged to have been smaller than those thereafter; and the above knowledges do not support the 'coral reef hypothesis' by Berger et al. that deposition of calcium carbonate into postglacial coral reefs has occurred from 15,000 years ago to 10,000 years ago. 30 refs., 2 figs.

  9. Studies of an application of mobile communication system to the private telecommunication network. Part 2. Trend of mobile communication systems and application to power utility; Idotai tsushin system no denryoku tsushinmo eno tekiyo. 2. Idotai tsushin system no genjo to denki jigyo eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Iwasaki, H. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1997-06-01

    This paper presents future prospects on development of different mobile communication systems operated by public communications operators, and discusses their application to power utilities. For automobile and cellular telephones, discussions are being made on the code division multiple access (CDMA) system which multiplexes and transmits information by using tally codes. Influence of noise decreases, and so does the need of retransmission due to code errors. Higher speed transmission than conventional systems may be expected. The system can be utilized for transmitting still images, such as for status of construction being carried out by power utility companies. For PHS, a discussion will start on 32 to 64-kbps transmission in fiscal 1997. By using the system together with an image compression technology, the system may be expected of utilization as a moving image transmission method for supporting site works by utility companies. The low and medium orbit satellite communications whose use is scheduled to start shortly can be utilized as construction and emergency disaster communication networks for mountainous areas and islands. Movements around the frequency band utilization and communication systems of IMT-2000 are becoming more complex. The Japanese proposal plans transmission of moving images, whereas more diverse utilization can be expected, such as for voice, data and images, in areas where no ground communication facilities are available for electric power operations. 16 refs., 4 figs., 3 tabs.

  10. Study of transmitting electric power utility communications in IP network. Transmission of existing electric power utility communications in best effort type IP network under delay constraint; Denryokuyo tsushin kaisen no IP mo eno shuyo kento. Chien jikan seiyakuka ni okeru best effort gata IP mo eno kison denryokuyo tsushin kaisen no shuyo

    Energy Technology Data Exchange (ETDEWEB)

    Miyake, H.

    2000-07-01

    Since IP network does best effort behavior fundamentally, it always generates delay time and delay variation. For this reason, IP network has been unsuitable to transmit real time data such as a voice. However, in recent years, the technologies which transmit real time data in IP network, e.g. VoIP, have spread. If it is possible to transmit the existing electric power utility communications in IP network using these technologies, total network cost can be reduced by the reduction of required bandwidth and the simplification of communication network systems. In this report, it is examined quantitatively whether end-end delay time of the existing electric power utility communications, e.g. on-line, telephone, carrier relay, CDT (cyclic digital transmission equipment), video conference, ITV(industrial television), is within their permission delay time when they are transmitted in the best effort type IP network. (author)

  11. Achievement report for fiscal 1997 on the research and development to lead to gas hydrate using technology. Research and development on exploration, research and development on drilling technologies, survey and research on a method to evaluate environmental impact, and survey and research on a utilization system; 1997 nendo gas haidoreto shigenka gijutsu sendo kenkyu kaihatsu seika hokokusho. Tansanado ni kansuru kenkyu kaihatsu, kussaku gijutsu ni kansuru kenkyu kaihatsu, kankyo eikyo hyokaho no chosa kenkyu, riyo system ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-09-01

    The present study is intended to analyze comprehensively geophysical, geological and geochemical data, and establish a technology to estimate distribution of gas hydrate (GH) in sea areas around Japan. It is also intended to develop a high-accuracy resource amount calculating method utilizing the result of excavation of GH planned in the future. In order to achieve these goals, the following activities are performed: (1) study on a method to estimate production environment of GH deposits, (2) development of a method to estimate GH stability areas by using the crust thermal flow measuring method, and (3) study on estimation of GH distribution and wide-area potential. For the study (1), an inorganic element analyzer was introduced, and calibration of devices was performed in fiscal 1997. A survey was carried out on literatures related to distribution of inorganic elements and process of GH deposit production. In the study (2), design and trial fabrication were executed on a high-accuracy crust thermal flow measuring device, capable of long-term continuous observation. In the study (3), re-processing focusing on BSR was implemented by using the latest computer and analysis software on the data in which BSR has been confirmed in the surveys done in the past on sea areas around Japan. (NEDO)

  12. Advanced research and development of gas hydrate resources. R and D of exploration and others - R and D of excavation technologies and others - surveys/researches on methods of evaluating environmental effects - surveys/researches on application systems; Gas hydrate shigenka gijutsu sendo kenkyu kaihatsu. Tansa nado ni kansuru kenkyu kaihatsu / kussaku gijutsu nado ni kansuru kenkyu kaihatsu / kankyo eikyo hyokaho no chosa kenkyu / riyo system ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Gas hydrate is a clathrate compound in a gaseous molecule as the host, stable under relatively mild environments. It is deposited in the 600m or deeper sea bottoms to form the gas hydrate deposit and massively occurring in the sea areas around Japan. This deposit has been studied viewed from natural gas resources, causes for natural hazards and contribution to the global warming. This project excavates a well in the deposit, to study possibilities of the technologies for decomposing, fluidizing and lifting the hydrate as the gas source, and for establishing the natural gas transporting/mooring systems in which its characteristics are utilized. The R and D activities are directed to the 4 areas, (1) development of the exploration technologies to determine the deposit sea area, quantity and conditions, (2) development of the stable well-excavation technologies, (3) studies on the effects of gas production on the environments, and development of the system for predicting the effects, (4) and studies on the application systems. The item (3) finds out the transportation/storage system possibly more economical than the current freezing/liquefaction technologies. The item (3) has the development themes of evaluating the geohazards caused by excavation and gas production, and their effects on the ecological systems. (NEDO)

  13. Report on the achievements in fiscal 1999. Technology to use gas hydrate as a resource (Research and development for exploration, research and development on drilling technologies, investigative research on an environment influence evaluation method, and investigative research on a utilization system); 1999 nendo gas hydrate shigenka gijutsu sendo kenkyu kaihatsu seika hokokusho. Tansa nado ni kansuru kenkyu kaihatsu, kussaku gijutsu nado ni kansuru kenkyu kaihatsu, kankyo eikyo hyokaho no chosa kenkyu, riyo system ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The contents of the research and development performed in the current fiscal year are as follows: (1) research and development for exploration, (2) research and development on drilling technologies, (3) investigative research on an environment influence evaluation method, and (4) investigative research on a utilization system. In Item (1), element analysis data are used to study a method to estimate production environment of hydrate ore beds by using an inorganic ion analyzer and a trace amount element analyzer, the crust thermal flow measuring method is used to discuss a method to analyze the hydrate stability zones together with the data of sea area exploration records, and conceptual design is made on a resource potential evaluation system. In Item (2), experiments and analytical discussions are performed on decomposition control of the gas hydrate solid-liquid interface according to such conditions for the drilling fluid as temperatures and flow rates. Elucidation is given on the initial process of bubble generation for behavior of decomposed gas bubbles. Observation and elucidation are made on two-phase flow behavior of non-Newtonian fluid. In Item (3), conceptual design is carried out on a system to detect elements of shape change in each bed due to fluid movement in a gas hydrate bed and an upper bed. In Item (4), discussions are given on the optimizing conditions for generation and dissociation of gas hydrates. Investigation is made also on a possibility of the transportation and storage system. (NEDO)

  14. FY 1998 annual report on the preliminary research and development of techniques for developing resources from gas-hydrate. Studies on gas-hydrate exploration, excavation techniques, methods for assessing environmental impacts, and gas hydrate handling systems; 1998 nendo gas hydrate shigenka gijutsu sendoken kaihatsu seika hokokusho. Tansanado ni kansuru kenkyu kaihatsu, kussaku gijutsu nado ni kansuru kenkyu kaihatsu, kankyo eikyo hyokaho no kenkyu kaihatsu, riyo system ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    This R and D project is for the preliminary studies on development of the following 4 types of techniques for developing resources from gas-hydrates (GH): (1) gas-hydrate exploration, (2) excavation techniques, (3) methods for assessing environmental impacts, and (4) gas hydrate handling systems. The FY 1988 R and D results are described. For gas-hydrate exploration, the methods for analyzing inorganic ions and trace quantities of elements, which are necessary for accurately estimating the offshore GH around Japan, are established; and case studies are conducted for methods of predicting GH deposit forming mechanisms, and stability fields of GH, based on terrestrial heat flow and seismic data. For excavation techniques, GH decomposition rate is analyzed using a laboratory system which reproduces conditions of excavation of GH layers. For methods for assessing environmental impacts, a geo-hazard predicting model is established, to study ground displacement and gas leakage sensing systems and data transmission systems to cope with the hazards. For gas hydrate handling systems, an overall system is studied, and storage and transportation systems are outlined. (NEDO)

  15. Resveratrol: A Multifunctional Compound Improving Endothelial Function

    OpenAIRE

    Li, Huige; F?rstermann, Ulrich

    2009-01-01

    The red wine polyphenol resveratrol boosts endothelium-dependent and -independent vasorelaxations. The improvement of endothelial function by resveratrol is largely attributable to nitric oxide (NO) derived from endothelial NO synthase (eNOS). By stimulating eNOS expression, eNOS phosphorylation and eNOS deacetylation, resveratrol enhances endothelial NO production. By upregulating antioxidant enzymes (superoxide dismutase, catalase and glutathione peroxidase) and suppressing the expression a...

  16. Vliv konečné apertury na přenos výkonu super-gaussovských svazků - analýza s využitím VirtualLabu

    Czech Academy of Sciences Publication Activity Database

    Stanke, Ladislav; Palatka, Miroslav

    2017-01-01

    Roč. 62, Jan (2017), s. 26-29 ISSN 0447-6441 R&D Projects: GA MŠk EF15_008/0000162 Grant - others:ELI Beamlines(XE) CZ.02.1.01/0.0/0.0/15_008/0000162 Institutional support: RVO:68378271 Keywords : beam clipping * super-Gaussian beams * simulation Subject RIV: BH - Optics, Masers, Lasers OBOR OECD: Optics (including laser optics and quantum optics)

  17. FY 1998 report on the results of R and D projects by local consortiums for immediate effects. Development of woody ceramics and application to building parts; 1998 nendo woody ceramics no sosei to kenchiku buzai nado eno oyo seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The R and D project has been implemented for developing materials for, e.g., light, highly heat-insulating and energy-saving type building parts (e.g., roofing tiles and tiles), and light tableware having warmness of wood. The stock materials for china and porcelain, roofing tile clay, tiles and cement are dispersed with hollow microcapsules as the filler, which are of glassy balloons thermally treated to be highly functional, in order to develop superlight, highly heat insulating and high-strength materials. For development of the woody ceramic materials, the microcapsules are investigated for size, thickness, thermal shrinkage, fusibility, compressive stress, reinforcing mechanisms, and monodispersibility. Also investigated are optimization of material formability, development of commercial ceramics and evaluation of their marketability, decoration techniques, antimicrobial membrane materials and their immobilization techniques, development of antimicrobial ceramic tiles, evaluation of the antimicrobial membranes, evaluation of resistance to microwaves, and so on. The efforts are also directed to researches on fundamental techniques for woody tile clay, and R and D of the application techniques and products of the woody cement. (NEDO)

  18. Polimorfísmos genéticos de COX-1 y eNOS y hemorragias gastrointestinales: interacción con aire: Un estudio de casos y controles

    OpenAIRE

    Salado Valdivieso, María Inés

    2014-01-01

    La hemorragia gastrointestinal alta es un cuadro grave que está producido por medicamentos en un porcentaje elevado de los casos. Ciertos fármacos como los antiinflamatorios no esteroideos (AINE), los antiagregantes plaquetarios o los anticoagulantes orales, pueden dar lugar a una hemorragia que exija la hospitalización del paciente y, en ocasiones, provoque la muerte. Además de los fármacos, se han identificado otros factores que se asocian con la hemorragia gastrointestinal; entre ellos es...

  19. Studies of initial stage in coal liquefaction. Effect of decomposition of oxygen-functional groups on coal liquefaction; Ekika hanno no shoki katei ni kansuru kenkyu. 3. Gansanso kannoki no bunkai kyodo to ekika hanno eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Komeiji, A.; Kaneko, T.; Shimazaki, K. [Nippon Brown Coal Liquefaction Co. Ltd., Tokyo (Japan)

    1996-10-28

    Pretreatment of brown coal in oil was conducted using 1-methyl naphthalene or mixture of tetralin and 1-methyl naphthalene as solvent at temperatures ranging from 300 to 430{degree}C under nitrogen atmosphere. Effects of the solvent properties on the structural change of oxygen-functional groups (OFG) and coal liquefaction were investigated by means of quantitative analysis of OFG and solid state {sup 13}C-NMR measurement. When hydrogen transfer from solvent was insufficient, it was suggested that brown coal molecules loose their hydrogen to be aromatized. While, at lower temperatures ranging from 300 to 350{degree}C, hydrogen contained in brown coal molecules was consumed for the stabilization of pyrolytic radicals, and the deterioration of liquefaction was not observed. When hydrogen transfer from solvent was insufficient at higher temperatures above 400{degree}C in nitrogen atmosphere during pretreatment in oil, crosslinking like benzofuran type was formed by dehydration condensation of hydroxyl group in brown coal, to deteriorate the liquefaction, remarkably. The addition of donor solvent like tetralin decreased the formation of crosslinking like benzofuran type, which suppressed the deterioration of liquefaction. 8 refs., 5 figs.

  20. Application of plasma sprayed ceramic coatings to the base materials of the rotating disk in the centrifugal atomization process. Enshinryoku funmuho ni okeru kaiten enban eno ceramic yosha himaku no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Sato, T; Okimoto, K [Government Industrial Research Inst., Kyushu, Tosu, Saga (Japan); Yasutake, R [Koeiseiko Co. Ltd., Fukuoka (Japan)

    1992-07-08

    Applicability of the ceramic coating on the rotating disk was studied. In regard to the synthesis of Cu-based rapidly solidified powders, centrifugal atomization with molten Cu-24.6Sn was carried out using rotating disks sprayed with four kinds of sprayed ceramic coatings. It was found that atomization of Al203-40%TiO2 sprayed coating has been the best, and the yield ratio has been about 60 %. The melt temperature in case of Fe-based rapidly solidified metal powders, has risen above 1600[degree]C, and the required conditions for rotating disk have been very difficult to meet. The reason for it is thought that there has also been limitations regarding the functions of the characteristics like heat transfer, heat capacity, etc. Fe-24Cr-5Ni-1Mo 2 phase stainless steel powder has shown the most suitable trend among the seven kinds of disk materials examined for ZrO2 ceramic sprayed coatings. 6 refs., 5 figs., 2 tabs.

  1. Research of the elastic waves generated by a pulse laser. Excitation mechanism of elastic waves and application to nondestructive testing; Pulse laser de reikishita danseiha ni kansuru kenkyu. Danseiha reiki no mechanism to hihakai kensa eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Cho, H.; Takemoto, M. [Aoyama Gakuin University, Tokyo (Japan). College of Science and Engineering

    1994-07-20

    A bulk wave is generated when a pulse laser is irradiated to the material, and the characteristics of a Young`s modulus and Poisson`s ratio can be nondestructively estimated from the bulk wave. The generation mechanism of laser ultrasonic waves must be first clarified for such application. In this paper, fundamental research was conducted to study the generation mechanism of the elastic waves excited by a Q-switched Nd-YAG laser, and the generation method and characteristics of Rayleigh waves. The following result was obtained. A bulk wave is generated by the disk-like adiabatic expansion near the surface if the laser power is small when a spot-shape pulse laser was irradiated. A bulk wave is generated by the thin disk-like adiabatic expansion beneath the surface due to the thermal diffusion in the depth direction of a base material when the laser power becomes large. Moreover, a bulk wave is generated by the impact force due to abrasion and plasma when the power becomes still larger. The information on the bulk wave characteristics and Rayleigh wave was also obtained. 25 refs., 15 figs., 1 tab.

  2. Three-dimensional computer simulation at vehicle collision using dynamic model. Application to various collision types; Rikigaku model ni yoru jidosha shototsuji no sanjigen kyodo simulation. Shushu no shototsu keitai eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Abe, M; Morisawa, M [Musashi Institute of Technology, Tokyo (Japan); Sato, T [Keio University, Tokyo (Japan); Kobayashi, K [Molex-Japan Co. Ltd., Tokyo (Japan)

    1997-10-01

    The past study of safety at vehicle collision pays attention to phenomena within the short time from starting collision, and the behavior of rollover is studied separating from that at collision. Most simulations of traffic accident are two-dimensional simulations. Therefore, it is indispensable for vehicle design to the analyze three-dimensional and continuous behavior from crash till stopping. Accordingly, in this study, the three-dimensional behavior of two vehicles at collision was simulated by computer using dynamic models. Then, by comparison of the calculated results with real vehicles` collision test data, it was confirmed that dynamic model of this study was reliable. 10 refs., 6 figs., 3 tabs.

  3. New concept of combustion technology in small DI diesel engines. 4th Report. Effects of fuel injection rates on MK combustion; Kogata chokufun diesel kikan no shinnensho concept. 4. Funsharitsu no MK nensho eno eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, S; Matsui, Y; Kamihara, T [Nissan Motor Co. Ltd., Tokyo (Japan)

    1997-10-01

    A previous paper showed that EGR cooling and a low compression ratio which prolongs the ignition delay can expand the area of the new combustion concept. Experimental investigations were conducted in this research to examine the effects of the fuel injection rates, the injection pressure and the injection duration, on the exhaust emissions of an engine incorporating the MK concept The results showed that a higher injection pressure was effective in reducing NOx and particulate matter (PM) under MK combustion conditions. 10 refs., 9 figs., 1 tab.

  4. CFD simulation of three-dimensional motion of a vehicle with movable wings. Application to the keel of a racing yacht; 3 jigen undo suru kado yokufu shinko buttai no CFD simulation. Racing yacht keel eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Takada, N. [Mitsubishi Heavy Industries Ltd., Tokyo (Japan); Sato, T. [Tokyo Univ. (Japan)

    1998-12-31

    The computational fluid dynamics (CFD) is so remarkably developed in the various kinds of science and technology fields that it is utilized in aeroplane and other machines and structures. The introduction of Navier-Stokes equation into the fixed coordinate system makes it possible to perform the CFD simulation of vigorously moving body. Combining its procedure with the moving grid scheme enables us to maneuver a moving wing. A body with complicated shape like the keel of racing yacht is expressed by the multi-block grid to develop the CFD code corresponding to it. The simulation of forced motion, which is the first step of the motion simulation system, is applied to the keel of racing yacht to prove that the viscous flow field around the complicatedly shaped body. 6 refs., 17 figs., 2 tabs.

  5. Biochemical and toxicological impacts of persistent organochlorines on aquatic ecosystem. With particular attention to dioxins and their related compounds; Zanryusei yuki enso kagobutsu no suiken seitaikei eno eikyo. Toku ni dioxin rui ni chakumokushite

    Energy Technology Data Exchange (ETDEWEB)

    Iwata, H. [Hokkaido University, Sapporo (Japan)

    1998-07-10

    PCDDs, PCDFs and coplanar PCBs are organochlorine compounds which induce toxicological impacts on test animals, such as reduced weight, thymic gland dwarf, hepatotoxicity, immunotoxicity, developmental toxicity, carcinogenecity, teratogenicity and endocrine disturbance. They are generally referred to as dioxins. They are difficult to be decomposed in vivo, and tend to be more concentrated in higher organisms, placed at higher positions in the food chain. In aquatic ecosystems, they are observed to accumulate at high concentrations in fishes, fish-eating birds, claspers and whales. Therefore, there are growing concerns over their possible adverse effects on wild animals in aquatic ecosystems. This paper describes the effects of persistent organochlorine compounds on fishes, birds and aquatic mammals; and induction of cytochrome P450 of each organic species, caused by exposure to dioxins, and the induction examples in aquatic ecosystems. It also discusses whether or not the cytochrome P450 induction capacity of each organism species can be used as an index which explains difference between organism species in toxicological impacts of dioxins. 33 refs., 1 fig., 1 tab.

  6. Report on the survey in fiscal 1998. Systematic arrangement of environment technologies. 5 (Application of advanced technologies to environmental measures); 1998 nendo chosa hokokusho. Kankyo gijutsu ni kansuru taikeiteki seiri. 5 (sentan gijutsu no kankyo taisaku eno oyo)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    Global environment handling technologies were investigated and put into order. Universities often make research and development on themes that can be handled at laboratory levels or by simulations. Development at a practical application level is few. Technological seeds may include manufacture of hydrogen by water and steam decomposition using solar energy, and new synthesizing reactions utilizing solar energy. Included may also be urban type wind power generation, superconductive energy storage systems, biomass utilization, and natural energy utilization. Furthermore, CO2 recovery and utilization by liquefaction, alkaline metal heat power generation, and pulse power technologies can also be found. Studies on applying advanced technologies to environmental measures include composite materials, membrane separation, photo-catalysts, optical elements, porous bodies, functional polymers, bio-reactors, electron beams, and aeration. Private corporations are working noticeably on prevention of fluorocarbon and dioxin emission, PCB treatment and waste water treatment technologies, catalyst application technologies, recycling technologies, and incineration ash treatment and utilization technologies. (NEDO)

  7. FY 1997 report on the survey of potential impacts of enlarging ASEAN on political and economic systems in South East Asia; 1997 nendo chosa hokokusho (ASEAN kakudai no Higashi Asia no seiji keizai chitsujo eno eikyo chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This report surveys potential impacts of ASEAN (Association of South East Asian Nations) on inter-ASEAN affairs and its external relations when ASEAN will enlarge its members to include all nations in South East Asia, and thus fully represent the region. For this purpose, the survey was conducted on Vietnam, Myanmar, Laos and Cambodia, which joined in 1995, from the viewpoint of their economic and political system, and their relations with other member countries. The nature of ASEAN has gradually transformed, in which all the countries in the region have increased and internal economic issues have been tackled. It has an aim to stimulate inter-ASEAN trade and induce foreign direct investment into ASEAN as a whole by reducing import duties on intra-ASEAN trade. Underlying in these, new development is a concern about growing economic and military power of China. ASEAN solidarity will work an leverage against China should change toward worse, and ASEAN will function as a regional stabilization factor. ASEAN is needed for the stability of both in economic and political order in East Asia. Japan has to further promote its cooperation with ASEAN to help its solidarity as an association. 24 refs., 21 figs., 25 tabs.

  8. Síntese da 5-metil-2-oxabiciclo[3.3.1]nom-7-eno-3,6-diona.Determinaçăo estrutural de uma lactona bioativa isolada de otoba parvifolia /

    OpenAIRE

    Lenz, Cesar Antonio

    2003-01-01

    Orientador: Francisco de Assis Marques Tese (doutorado) - Universidade Federal do Paraná, Setor de Cięncias Exatas, Programa de Pós-Graduaçăo em Química. Defesa: Curitiba, 2003 Inclui bibliografia

  9. Bussijuhtide streigi ärahoidmiseks on täna jäänud viimane võimalus / Ingvar Bärenklau, Hindrek Riikoja, Eno-Gerrit Link

    Index Scriptorium Estoniae

    Bärenklau, Ingvar, 1967-

    2007-01-01

    Ilmunud ka: Postimees : na russkom jazõke, 11. dets. 2007, lk. 6. Postimees : na russkom jazõke lüh. Transpordi ametiühingu ja autoettevõtete liidu delegatsioonid annavad hinnangu riikliku lepitaja ettepanekule palgatüli lahendamiseks, mis on viimane võimalus üldstreigi ärahoidmiseks. Lisa: Võimaliku streigi ajakava; Kuidas elab Tartu streigipäevadel?; Streigid ja streigiähvardused. Vt. samas intervjuud bussijuht Leo Sillastega: 6000-kroonist kuupalka peetakse kodus valejutuks; Pärnu bussijuhid on streigi osas ühel meelel

  10. Study of combustion in microgravity environments and application of the findings to combustors for industrial use; Bisho juryoku kankyoka ni okeru nensho kenkyu oyobi sangyoyo nensho kiki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Sato, J. [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1997-09-10

    Natural convection is one of the factors that make the elucidation of the combustion phenomenon difficult. Such being the case, it is necessary to utilize microgravity enviroments to learn fuel combustion characteristics and parameters governing the combustion phenomenon for the development of optimal burning appliances. The free-fall facility of JAMIC (Japan Micro Gravity Center) creates a microgravity field that lasts for 10 seconds, and helps perform various combustion-related researches. This report outlines the findings obtained thanks to the use of this facility. In a `study concerning the creation of sophisticated combustion technology,` the combustion of 50{mu}m fuel droplets (too small to involve natural convetion) in a jet engine combustor is simulated in a microgravity field using experimentally producible 1mm drops, and the relationship between the droplet burn time and pressure is disclosed. In addition, using a small combustion furnace, the behavior of a natural-size flame is estimated and the propagation speed of a carbon powder flame is studied. 6 figs.

  11. Synthesis and Characterisation of Tris(1-carboxyl-2-phenyl-1,2-ethyl eno dithiol enic-S,S') Tungsten Complex as Photo catalyst for Photolysis of H2O Molecules

    International Nuclear Information System (INIS)

    Fadhli Hadana Rahman; Rusli Daik; Mohammad Kassim; Khuzaimah; Wan Ramli Wan Daud

    2008-01-01

    Tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex is one of the most promising photo catalyst to be used in photolysis of water to produce hydrogen. The first step of the synthesis involves a metathesis reaction of tetrapropylammonium bromide [((C 3 H 7 ) 4 N)Br] and ammonium tetrathiotungstate [(NH 4 ) 2 WS 4 ] to form a tetrapropylammonium tetrathiotungstate [((C 3 H 7 ) 4 N) 2 WS 4 ] (precursor). Then, the precursor was reacted with phenyl acetylenecarboxylic acid (C 9 H 6 O 2 ) to form tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex (C 27 H 18 O 2 S 6 W). The infra-red, ultra violet/ visible (UV/ Vis) spectrum, nuclear magnetic resonance (NMR) and elemental micro-analysis of C, H, N and S agreed with the characteristic of the tris(1-carboxyl-2-phenyl-1,2-ethylenodithiolenic-S,S ' ) tungsten complex. The (W-S), (C-S) and (C=O) stretching frequencies were detected at 511, (1470 and 1035) and 1655 cm -1 , respectively. The 1 H NMR spectrum showed six protons in the complex. The 13 C NMR showed only 7 signals for carbon atom in the benzene ring, ethylene groups and carboxylic acid pendant group due to the symmetry of the molecules. The reaction yield was about 50 percent. Photolysis of acetone spiked H 2 O showed that the catalyst was able to produced 1.8 μmol/ h hydrogen. (author)

  12. Electrolyte loss mechanism of molten carbonate fuel cells. 2.; Application to the cell with matrix electrolyte layer; Yoyu tansan`engata nenryo denchi ni okeru denkaishitsu loss kiko ni tsuite. 2.; Matrix gata denkaishitsuso wo yusuru denchi eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Sonai, A; Murata, K [Toshiba Research and Development Center, Kawasaki (Japan)

    1993-11-01

    A single cell of molten carbonate fuel cell using a matrix electrolyte layer fabricated by using the doctor blade process has been operated for several thousand hours, measured of electrolyte loss amount, and analyzed by using a new electrolyte loss mechanism. The result may be summarized as follows: according to a result of measuring the matrix layer pore distribution, the average pore size has increased little by little; pores with diameters greater than 2 {mu}m at which no electrolyte retention becomes possible remain at nearly constant ratio up to 1800 hours, but increased after 2500 hours; the pore capacity in ports with the largest electrolyte retaining diameter of 2 {mu}m or less showed slight decrease with time in the anode, and an initial decrease followed by flatness, and then a sharp decrease after 1800 hours in the matrix layer; the electrolyte loss measurement values have remained nearly constant for 25 hours to 1800 hours, but increased sharply thereafter; and the electrolyte loss in this single cell due to pore capacity decrease in pores as power generating parts with diameters smaller than 2 {mu}m was explained quantitatively by a new electrolyte loss mechanism. 11 refs., 6 figs.

  13. Fázově koherentní přenos stabilní optické frekvence Brno - Praha po optickém vlákně délky 306 km

    Czech Academy of Sciences Publication Activity Database

    Číp, Ondřej; Čížek, Martin; Pravdová, Lenka; Hucl, Václav; Řeřucha, Šimon; Hrabina, Jan; Mikel, Břetislav; Lazar, Josef; Vojtěch, J.; Smotlacha, V.

    2016-01-01

    Roč. 61, 4-5 (2016), s. 91-97 ISSN 0447-6441 R&D Projects: GA ČR GB14-36681G; GA MŠk(CZ) LO1212; GA MŠk ED0017/01/01 Institutional support: RVO:68081731 Keywords : laser * optical fiber * optical and frequency transfer * optical frequency standard Subject RIV: BH - Optics, Masers, Lasers

  14. Epidemias de ferrugem asiática no Rio Grande do Sul explicadas pelo fenômeno ENOS e pela incidência da doença na entressafra

    Directory of Open Access Journals (Sweden)

    Claudinei Antonio Minchio

    Full Text Available RESUMO Estudou-se a interferência da variabilidade da variabilidade climática e do número de relatos de ferrugem asiática na entressafra sobre a epidemia da doença no estado do Rio Grande do Sul, durante 11 safras agrícolas. A ocorrência da doença foi obtida a partir de relatos apresentados no Consórcio Antiferrugem e dividida entre os períodos “Safra”, “Entressafra” e “Ano Todo”. Os dados das epidemias foram testados para correlação, via regressões polinomiais lineares e quadráticas, com as variáveis climáticas: precipitação pluvial, índice padronizado de precipitação - SPI, índice de oscilação sul - IOS e anomalia da Temperatura na Superfície do Mar - SST no Oceano Pacífico Tropical e número de ocorrências da doença no período de entressafra. Os índices que melhor explicaram a variação das ocorrências da doença para o período “Ano Todo” foram o SST e IOS, com coeficientes de determinação (R2 de 0,94 e 0,59, respectivamente. As ocorrências de ferrugem no período “Entressafra” influenciaram positivamente nas ocorrências no período “Safra”.

  15. Application of waste tires to asphalt pavement. Improvement of adhesion of asphalt with rubber particles; Haitaiya no asphalt hoso eno tekiyo. Asphalt to gomu ryushi no fuchakusei no kairyo ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Nakaoka, I. [Kansai Electric Power Co. Inc., Osaka (Japan)

    1994-10-10

    With an objective to apply waste tires to asphalt pavement, an experiment was carried out to improve adhesion of asphalt with rubber particles by using polymers. The state of interface on rubber particle and asphalt mixture was observed by a scanning electron microscope. As a result, it was found that the surface of untreated rubber particles is not bonded with the asphalt, but polymer treated mixture was found to have the affinity of rubber particles with asphalt improved. Tensile bonding strength was tested on rubber plates and asphalt. The result revealed that the polymer-reformed mixture has two times as large tensile bonding strength as that of the untreated mixture. With regard to the characters of asphalt mixture mixed with rubber particles, the stability shows a decreasing trend as compared with the standard asphalt concrete, but presents an excellent performance in wear. The fluidity resistance value is inferior to the standard, but not as great as presenting a problem under normal using environment, where its applicability as a road paving material was verified. 4 figs., 2 tabs.

  16. FY1995 study of ultra high resolution laser and microwave spectroscopy and its application to future standards; 1995 nendo choseimitsu laser micro ha bunko to sono jisedai hyojun eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    Ultra high resolution spectroscopy is carried out in a range from microwave to ultraviolet using lasers with laser cooling, saturated absorption, 2 photon absorption and ion trap, and optical parametric oscillation is studied for optical frequency measurement. A temperature of 10 {mu}K and that of 150 mK were obtained for Cs atoms and a single Yb ion, respectively. A stability of 3.3 x 10{sup -12} was obtained for iodine stabilized YAG lasers. A saturation signal of C{sub 2}H{sub 2} was observed during wore than 9 months. An optical parametric oscillator, which was fabricated to measure an optical frequency, was probed to work continuously more than 3 hours. (NEDO)

  17. Development of a readily recyclable sound insulation material made of polyester fibers. Application of the PET fibers from plastic bottles; Recycle kanona jidoshayo polyester sei kyuon zairyo no kaihatsu. Shiyozumi pet bottle zai no insulator zai eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Nemoto, K; Watanabe, K; Sugawara, H; Minemura, Y [Nissan Motor Co. Ltd., Tokyo (Japan)

    1997-10-01

    We have developed new polyester sound-absorbing materials made of fine and modified-cross-section polyester fabric. They provide noticeably higher sound-absorbing performance than traditional materials. Another feature of the new materials is their excellent recyclability since they are made of polyester. Application of the new materials to the dash silencer and the floor carpeting produced a great improvement in sound-insulation performance with less weight. 2 refs., 7 figs.

  18. Development II of ion current combustion control system. Application to the lean burn system of the micro vehicle engine; Ion denryu wo mochiita nensho seigyo system no kaihatsu. 2. Keijidosha engine wo mochiita lean burn eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Iida, T; Asano, M; Kajitani, M; Kuma, t; Morinaga, Y [Daihatsu Motor Co. Ltd., Osaka (Japan)

    1997-10-01

    The lean bum engine has not been introduced into the micro vehicle so far because of the low cost requirement and small displacement, in spite of it is one of the effective solutions which increase the fuel economy. By the way, we had already reported in the former paper that we developed the ion current combustion control system the architecture of which is cheaper than the other system. In this paper, we described the way how the above system is applied to the lean burn system of the micro vehicle engine and also we reported the gain of fuel economy and the exhaust emission level. 5 refs., 11 figs., 2 tabs.

  19. Life cycle assessment of supercharger for automotive use. Small displacement, high charging pressure engine and environmental load; Jidosha tosaiyo supercharger no life cycle assessment (LCA hyoka). Shohaikiryo kokakyu engine no kankyo eno yasashisa

    Energy Technology Data Exchange (ETDEWEB)

    Takabe, S; Sonoya, T; Hara, M [Ishikawajima-Harima Heavy Industries Co. Ltd., Tokyo (Japan)

    1997-10-01

    In resent years environmental conservation requires low fuel consumption and low emission engine. And environmental load of every car life stage (production, using, abolition) is considered. Life Cycle Assessment of supercharging small displacement engine is reported, compared with natural aspirated engine as same maximum torque and maximum power as supercharging engine. 6 refs., 8 figs., 3 tabs.

  20. Strain measurement of wheel by a super-small size strain history recorder and its application to fatigue design; Chokogata jitsudo hizumi keisoku sochi ni yoru wheel no hizumi keisoku to hiro kyodo sekkei eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Murakami, Y [Kyushu University, Fukuoka (Japan); Mineki, K; Wakamatsu, K [Central Motor Wheel, Tokyo (Japan); Morita, T

    1997-10-01

    A very small strain history recorder based on the rainflow method has been developed and applied to strain measurement of car wheels under several road tests. Various strain amplitude histogram data under mountain road, city road and high-way were acquired by the recorder for various types of wheels. The data were studied from the viewpoint of random fatigue and the fatigue damages were evaluated by Miner`s rule. The results of the damage evaluation were used for the improvement of shapes of wheels. 2 refs., 6 figs., 1 tab.

  1. Achievement report on the research on possibility of expanding application of information technology to automobile production line; Jidosha seisan kotei eno joho tsushin gijutsu tekiyo kakudai kanosei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Before submitting propositions on important technological tasks to be generated in the automobile production line upon application of IT (information technology), a questionnairing is implemented to know the actualities of the line for the purpose of planning a proper merger of IT and the manufacturing technology development capability of the IT accepting site. The questionnaire, aiming at the embodiment of the goals of the projects 'IT related technical tasks relative to its helping human creation of new technologies and enhancement of human ability to make improvement' and 'Technical tasks of developing technical skills into technologies,' asks engineers about the actualities of knowhow at automobile production lines and its development into technologies, about how they take care of what they learned from their predecessors, and about their expectations from and views and opinions toward IT introduction and utilization. It is important to efficiently utilize IT as a means to solve problems involving the knowhow related training on the production line and the handing down of the acquired knowhow to the juniors. Since individual workers' knowhow assumes a certain role at each stage of the automobile production line and since it is necessary to extract the maximum from each worker and to utilize the fruit for improvement on productivity and work efficiency, it is indispensable to efficiently merge the knowhow with IT. (NEDO)

  2. Study on electrical monitoring of fill-up improvement. Utilization of resistivity data for soil compaction management; Hiteiko mitsudo kanri ni kansuru kisoteki kenkyu. Moritsuchi seko kanri eno hiteiko yuko riyo

    Energy Technology Data Exchange (ETDEWEB)

    Ueno, N; Hiramatsu, W [Dai Nippon Construction, Gifu (Japan); Sugano, T [Kyoto University, Kyoto (Japan). Faculty of Engineering

    1996-10-01

    At present, measurement of wet density and water content by radio isotope (RI method) is used for filling management. It is supposed for filling in road construction that putting-out thickness of banking material reaches nearly 1m in the future rapid construction, however, use of RI method is difficult because of inserting and installing of a radiation source rod, large measuring apparatus, and the legal regulation on radioactivity intensity. Application of resistivity measurement was thus considered. Since resistivity has the same parameter as compaction curve, and monotonously decreases with an increase in water content by volume, it is applicable as construction management index. The management reference of resistivity (Rm) is set by plotting of a compaction curve and corresponding resistivity curve, determination of the reference resistivity (Ro) corresponding to a maximum dry density and optimum water content ratio, and setting of the allowance to Ro according to soil or application. It was clarified that Rm is applicable as set for every filling material. 1 ref., 10 figs., 2 tabs.

  3. Application of magnetotelluric method to hydrocarbon exploration. Case study of MT survey in Yurihara oil and gas field, Akita prefecture; MT ho no kokunai sekiyu tanko eno tekiyo. Akitaken Yurihara chiiki ni okeru jikken chosa kekka

    Energy Technology Data Exchange (ETDEWEB)

    Mitsuhata, Y; Matsuo, K; Ishikawa, H; Tanaka, H; Nakagami, K [Japan National Oil Corp., Tokyo (Japan). Technology Research Center

    1996-10-01

    The experiment and survey were carried out to verify the effectiveness and limitation of MT method. The previous seismic reflection method is unsuitable for steep terrain and over-folded complicated geological structure. In such difficult areas, application of MT method is increasing as complement or substitution for the reflection method. However, the evaluation of resistivity structure interpretation for every area is slightly difficult because of lack of data, poor quality of data, and no verification data at boreholes. Consequently, the survey was again carried out in well-known Yurihara oil and gas field, Akita prefecture whose geological structure has been surveyed in detail at boreholes, by adding new 32 sites, 22 sites on the south side and 10 sites on the north side of the measuring line extending from east to west. As a result, it was clarified that the lower high-resistivity layer found by MT method is equal to the Nishikurosawa basaltic layer, and basalt extends to the west in the north area. This result can`t be simply compared with the previous geological profile. 8 refs., 8 figs.

  4. Hodnocení efektivity vynaložených prostředků na reklamu během sportovních přenosů

    OpenAIRE

    Kozlová, Natálie

    2015-01-01

    Title: Evaluation of the effectiveness of advertising expenses during sport broadcasts Objectives: The main goal of this work is to compare the amount of money invested into the commercial advertisement during sport broadcasts at the ČT sport channel with viewer ratings. The used metric is a coefficient computed as a ratio between the viewer rating of the particular broadcast and the corresponding advertisement cost, normalized using Cost per Thousand method. Methods: Analysis of the secondar...

  5. Advanced mineral and lithological mapping using high spectral resolution TIR data from the active CO2 remote sensing system; CO2 laser wo mochiita kosupekutoru bunkaino netsusekigai remote sensing data no ganseki kobutsu shikibetsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Okada, K [Sumitomo Metal Mining Co. Ltd., Osaka (Japan); Hato, M [Earth Remote Sensing Data Analysis Center, Tokyo (Japan); Cudahy, T; Tapley, I

    1997-05-27

    A study was conducted on rock/mineral mapping technology for the metal ore deposit survey using MIRACO2LAS, an active type thermal infrared ray remote sensing system which was developed by CSIRO of Australia and is now the highest in spectral resolution in the world, and TIMS of NASA which is a passive type system. The area for the survey is the area of Olary/Broken Hill and Mt. Fitton of Australia. A good correlation is seen between the ground reflectance measured by MIRACO2LAS and the value measured by the chamber CO2 laser of rocks sampled at the above-mentioned area. In case that the width of spectral characteristics is below 300nm, the inspection ability by MIRACO2LAS`s high spectral resolution is more determined in mineral mapping as compared with TIMS which is large in band width. Minerals mapped using MIRACO2LAS are quartz, talc, amphibole, hornblende, garnet, supessartine, dolomite, magnesite, etc. 4 refs., 3 figs.

  6. Sterilization using ozone-ion gas sterilization using ozone-ion gas for mattresses used by the elderly; Ozone ion kunjoho ni kansuru kenkyu. Ozone ion kunjoho no zaitaku kaigoyo mattress mekkin eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Mikami, H.; Suzuki, A.; Hamasaki, H. [Shinryo Corp., Tokyo (Japan); Ishikawa, S.; Miyata, M.; Nanba, T. [Kitasato Univ., Tokyo (Japan); Sueyoshi, K. [Mitsubishi Research Institute Inc., Tokyo (Japan)

    1999-05-25

    The new generation of Japanese is facing an aging society: the number of young people is decreasing dramatically, while the number of elderly is increasing. Consequently, care for the elderly has become a big problem. One particular problem area we`ve investigated is the use of unclean mattresses by the bedridden elderly. These mattresses provide an all too excellent environments for the growth of microbes. We measured the density of microbes on the cover of mattresses at 775cfu/cm{sup 2} and in the bed filling at 136cfu/g. The dominant species of microbes were MRSA and Bacillus. We used MRSA, Bacillus subtilis and Escherichia coli as biological indicators and tested whether our system using ozone-ion fumigants was applicable for sterilization of mattresses. The survival ratio of MRSA were 10{sup -8} {approx} 10{sup -9}, 10{sup -7} {approx} 10{sup -8} for B. subtilis and below 10{sup -8} for E. coli. These experiments made it clear that our system is applicable for sterilization of the mattresses used by bedfast elderly. (author)

  7. Adoption of a fiber reinforced plastics (FRP) inner cylinder for the chimney stack at the Wakayama power plant; Wakayama hatsudensho entotsu eno FRP sei naito no saiyo ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Hirakawa, M. [Kansai Electric Power Co. Inc., Osaka (Japan)

    2000-05-10

    The chimney stack at the Wakayama power plant is planned to adopt a fiber reinforced plastics (FRP) inner cylinder having greater cost reduction effect than a steel made inner cylinder. The present study has performed different experiments on FRP under the gas emitting condition at the Wakayama power plant, and discussed structural plans based on the result therefrom. The Wakayama power plant has the waste gas raised in temperature because of difference in the power generation system. Therefore, physical constant verification tests and heat resistance tests were performed on FRP to verify its applicability. Structural discussions to pursue economy were given on the 'joints' and 'suspension points' (supporting points to suspend the FRP inner cylinder) being the major FRP structures based on the actual record at the Nanko power plant. The tests have placed focus on the 'heat resistance', and different experiments were carried out upon selecting two kinds of novolak-based vinyl ester resins. As a result, applicability of the FRP made inner cylinder to high waste gas temperatures was verified, and so were various property values to be used for designing the cylinder. Structural design was performed by applying design safety factor to the derived property values, and the basic structural plan was established for the FRP inner cylinder. (NEDO)

  8. Report for fiscal 2000 investigations on Activities Implemented Jointly in China and promotion of transfer to CDM; 2000 nendo Chugoku ni okeru kyodo jisshi katsudo oyobi CDM eno iko suishin chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    It is purposed to promote the Activities Implemented Jointly (AIJ) and the clean development mechanism (CDM) intended of reducing carbon dioxide emission amount in China. Investigations have been performed on China's environment and energy problems, CDM assignments and transfer means, and project candidates. China emits a great amount of CO2 due to coal combustion, and the CO2 emission is anticipated to increase from the coal burning thermal power generation that may continue into the future. Countermeasures for the thermal power department as the object are required. Since 1997, China has been performing the AIJ project with Norway, Japan, and America, wherein such projects have been implemented with Japan as the dry coke fire extinguishing facility model project, the energy saving model project using alloy iron electric furnaces, and the model project to utilize effectively the refuse combustion waste heat. China is one of the countries in which the greenhouse effect gas emission reducing project can be performed at a minimum cost, who will be the important party in the CDM performed by the developed countries to achieve their obligation to reduce the greenhouse effect gas emission. (NEDO)

  9. Evaluation report on the study on the application of 3D woven C/C composite materials; Sanjigenori C/C composite zairyo no kikai buhin eno oyo ni kansuru kenkyu hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper described a study made during 1995 through 1998 on the application of 3D woven C/C composite materials to machine parts. The materials are large in rigidity, small in specific gravity, excellent in specific rigidity, and suitable for high speed rotation. They are excellent in heat resistance/dynamic reformation and expected as materials which can exceed limits of the existing steel for machine parts. However, to use them as machine parts, a possibility of high precision cutting is required. Therefore, a study was made on metal multi-layer membrane coating to C/C composites. Pitch-system high-elastic carbon fibers were made a 4-directional material by orienting horizontally in 3 directions at 120 degrees per plane and also orienting vertically. Various materials such as W, Mo and WC were coated by the laser assisted plasma hybrid spraying method. High adhesion coats with little pore were obtained. Multi-directionally woven C/C composites used to be poor in surface precision workability, but the problem was able to be solved by coating surfaces with metal layers and metal multi-layer membranes. The application is expanded not only to polygonal mirrors (for laser printing machine) and milling spindles, but largely to machine parts. 11 figs., 1 tab.

  10. Fiscal 1999 survey report. Survey of leading countries' approaches to biomass energy development; 1999 nendo shuyokoku ni okeru biomass energy kaihatsu eno torikumi ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The survey aims to help Japan deliberate its future biomass energy development strategy including the course Japan is to follow in its research and development of biomass energy by clarifying leading countries' approaches to the subject matter and trends of their research and development efforts in this connection. The states of biomass energy development in the U.S. and Europe are reported. In the U.S., President Clinton issued Executive Order 13134 on August 12, 1999, regarding bio-based products and bioenergy development. In this country, bioenergy and bio-based production technologies have developed to reach a stage where business pays, and commercial plants are in service. The U.S. Administration mentions as a strategy the efficient development of the bioenergy industry. In Europe, where resources are versatile and local, it is difficult to assess the economy of scale, and small-scale development efforts are being accumulated. Practical technologies under development mostly involve direct combustion. European measures are similar to U.S. measures in that such political goals as local development and employment promotion are firmly woven into them. (NEDO)

  11. Měření dohlednosti kamerou pro účely studia vlivu reálné atmosféry na přenos optického bezkabelového spoje

    Czech Academy of Sciences Publication Activity Database

    Brázda, V.; Fišer, Ondřej

    2013-01-01

    Roč. 2013, č. 1 (2013) ISSN 1802-4564 R&D Pro jects: GA ČR(CZ) GAP102/11/1376 Institutional support: RVO:68378289 Keywords : visibility * digital camera * free space optical link Subject RIV: DG - Athmosphere Sciences, Meteorology http://147.228.94.30/index.php?option=com_content&view=article&id=369:meni-dohlednosti-kamerou- pro -uely-studia-vlivu-realne-atmosfery-na-penos-optickeho-bezkabeloveho-spoje&catid=44:islo-12013&Itemid=51

  12. Environmental science, petroleum engineer`s view. CO2 gas reduction technologies for global warming prevention; Sekiyu gijutsusha no shiten kara no kankyo kagaku. Chikyu ondanka eno taio no tame no CO{sub 2} yokusei gijutsu

    Energy Technology Data Exchange (ETDEWEB)

    Nomura, K [Tokyo (Japan)

    1998-08-01

    This paper discusses the techniques concerning diesel engines for cogeneration systems, techniques concerning fuel consumption-saving type lubricating oils and techniques concerning oil refineries, out of the CO2 emission control (energy saving) techniques for coping with the global warming which the petroleum engineers are now tackling. The paper introduces CO2 emission control techniques using a petroleum cogeneration system and studies on NOx removing techniques using catalysts as the techniques concerning diesel engines; techniques for reducing friction loss, which occurs in an engine and a transmission, by improving the recipes of lubricating oils and the development of novel friction modifiers as the fuel consumption-saving type lubricating oil techniques; and the CO2 separating techniques using a system for recovering the low-temperature waste heat produced in petroleum refinement with a high efficiency, or using a solid film such as a molecular sieve as the energy-saving techniques used in oil refineries. 18 refs., 8 figs., 1 tab.

  13. Achievement report on the survey concerning possibility of expansion of ITS technology application to various mobility systems; Kakushu mobility system eno ITS gijutsu tekiyo kakudai kanosei ni kansuru chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The project aims to evaluate the results so far achieved in 'The research and development of ITS (intelligent transportation system) by use of clean energy vehicles' and 'Research and development of ITS technology assisted mobility systems' and the development systems under which the efforts are exerted and to evaluate the possibility of their practical application and the spread of the effects brought about. Ex post facto evaluation is conducted of two types of test systems. The first type includes a rent-a-car for business use in the urban area, a rent-a-car for sightseeing, and a system which is an ITS provided electric car as a domestic second car in the residential district. The second type includes a shuttle bus park-and-ride system and a natural gas fueled physical distribution truck. The result is that the ITS provided electric car system is evaluated high by evaluation committee members. The score lowers in the order of the system for business use in the urban area, the system for sightseeing, and the second car system in the residential district. An electric car reduces its environmental impact when it uses a power generation system that utilizes renewable energy. It has become clear that high convenience will be achieved when a dispatching system is improved for a combination of a 'subminiature electric vehicle and ITS technology' as a method to satisfy the demand for commutation means in case the clientele is one or two people. (NEDO)

  14. Research report for fiscal 1998. Basic research for promoting joint implementation, etc. (conversion of old coal-fired thermoelectric power plants in Poland into combined cycle plants); 1998 nendo chosa hokokusho. Poland sekitan karyoku hatsudensho (kyushiki) combined cycle eno tenkan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A project is discussed for modernization for energy efficiency enhancement and greenhouse gas reduction. The most effective way to reduce greenhouse gas in Poland is to totally replace the existing coal-fired power plants with natural gas combined cycle plants. Under this project, however, natural gas-fired power generation and integrated coal/brown coal gasification combined cycle power generation are both subjected to study. This is because the power plant modernization project is closely related to the fate of coal/brown coal industries which constitute the important industrial department of Poland. As for the earning rate of the project in case of natural gas-fired combined cycle power generation, the rate will be 13.2% even at the Kaweczyn station which is the highest in earning rate, and this fails to satisfy the project conditions. If integrated coal/brown gasification combined cycle power generation is chosen, the rate will be still lower. When the cost for greenhouse gas reduction is taken up, the Konin station exhibits the lowest of 9 dollars/tCO2, and the others 15-17 dollars/tCO2. When coal gas combined cycle is employed, the cost will be 3-4 times higher. (NEDO)

  15. Fracture mechanical modeling of brittle crack propagation and arrest of steel. 3. Application to duplex-type test; Kozai no zeisei kiretsu denpa teisi no rikigaku model. 3. Konseigata shiken eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, S.; Tsuchida, Y. [Nippon Steel Corp., Tokyo (Japan); Machida, S.; Yoshinari, H. [The University of Tokyo, Tokyo (Japan). Faculty of Engineering

    1996-12-31

    A proposal was made previously on a model of brittle crack propagation and arrest that considers the effect of crack opening suppression by using unbroken ligaments generated on steel plate surface and the effect that cracks precede in the central part of the plate thickness, based on a local limit stress theory for brittleness fracture. This paper discusses applicability of this model to a mixed type test, and elucidates causes for difference in the arrest tenacity of both types in a double tensile test of the standard size. The brittle crack propagation and arrest model based on the local limit stress theory was found applicable to a simulation of the mixed type test. Experimental crack propagation speed history and behavior of the arrest were reproduced nearly completely by using this model. When load stress is increased, the arrests in the mixed type test may be classified into arrests of both inside the steel plate and near the surface, cracks in the former position or arrest in the latter position, and rush of cracks into both positions. Furthermore, at higher stresses, the propagation speed drops once after cracks rushed into the test plate, but turns to a rise, leading to propagation and piercing. 8 refs., 15 figs., 3 tabs.

  16. Ultimate strength analysis of thin plated structures using eigen-functions. 3rd Report. Application to reliability analysis; Koyu kansu wo mochiita usuita kozobutsu no dansosei kaisekiho. 3. Shinraisei kaiseki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ueda, Y. [Osaka University, Osaka (Japan). Welding Research Institute; Masaoka, K.; Okada, H. [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1996-12-31

    A reliability analysis was performed on ultimate strength of a hull by introducing reliability engineerings into the idealized structural unit method. Elements developed under the present study were applied to a model of an actual structure to indicate that even an analysis requiring much time under the finite element method can be performed in a short time and at high accuracy when this method is used. Analysis acted with bending moment and shear force simultaneously was performed on a model used as a structure in experiments carried out by Nishihara, assuming pure bending moment and longitudinal strength during slamming. Then, a reliability analysis was conducted on the same model based on this analysis method to investigate the ultimate strength. In an analysis of an ultimate strength when bending and shearing that assume slamming act upon simultaneously, axial force in the hull side decreases as loading increases, wherein how the shearing force increases can be identified clearly. Although existence of initial bends reduces the strength, the effect of variance in the vicinity of the average value on the reliability is rather small, while the effect due to variance in yield stress is greater. 27 refs., 14 figs., 4 tabs.

  17. Equivalent CTOD concept based on the local approach and its application to fracture performance evaluation of welded joints; Local approach ni motozuku toka CTOD gainen no teian to tsugite hakai seino hyoka eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ohata, M.; Minami, F.; Toyoda, M. [Osaka University, Osaka (Japan). Faculty of Engineering; Tanaka, T.; Arimochi, K. [Sumitomo Metal Industries, Ltd., Osaka (Japan); Glover, A. [Nova Gas Transmission Ltd., Calgary (Canada); North, T. [University of Toronto (Canada)

    1996-12-31

    A proposal was given on an equivalent crack tip opening displacement (CTOD) concept which relates quantitatively fracture performance of a structural member with the result of a three-point bending CTOD test via the Weibull stress based on a local approach. The equivalent CTOD is defined as a CTOD in which a three-point CTOD test piece and a structural member provide the same Weibull stress. Experimental and analytical discussions were performed on X80 steel welded joints. Effectiveness of the equivalent CTOD concept was verified from the fact that the fracture performance in welded joints with a large width estimated from the result of the three-point bending CTOD test using the equivalent CTOD concept showed good correspondence with the fracture performance obtained in the experiments. On the other hand, the result of estimation using the conventional CTOD concept is considerably smaller than measurements. As an application of the equivalent CTOD concept, a new determination procedure was introduced on required fracture tenacity to ensure deformation performance required on structural elements. The required CTOD value shows a trend that the smaller the ratio of yield stress of the welded metals to that in the base material, the greater the required CTOD grows. 16 refs., 19 figs., 3 tabs.

  18. Present situation, current problems and countermeasures to solve them by the material technology group in chemical companies; Kagaku shakai ni okeru sochi zairyo gijutsu no genjo to kadai oyobi sore eno taio

    Energy Technology Data Exchange (ETDEWEB)

    Nakahara, Masao. [Asahi Chemical Industry Corp., Tokyo (Japan). Production Technology Center

    1999-05-15

    A questionnaire investigation about the present situation, current problems and countermeasure to be discussed with by material technology groups in the eight chemical companies was carried out. It has become clear from the analysis of answers obtained that the roll of material group has been changing under the diminishing construction of new plant and the increased needs of stable and sustainable plant operation. The present major subjects of material groups, which are pointed out in the answers, are such new technological problems as the plant life estimation, the dissemination and handing down of material technology and the upbringing of technology successors. The countermeasures to meet those requirements made clear are such technology developments as a new monitoring system, preparation of database on material technology and closer cooperation with relatied associations. It is hoped for that the findings of this study would lead to further and more detailed indentification of common problems to be solved and development of practical countermeasures therefor. (author)

  19. Application of a temperature selective storage tank solar system. Part 4. Fundamental experiment under a solar simulator; Ondo sentaku chikunetsuso no solar system eno tekiyo. 4. Solar simulator ni yoru kiso jikken

    Energy Technology Data Exchange (ETDEWEB)

    Kanayama, K; Endo, N; Baba, H; Okamoto, A [Kitami Institute of Technology, Hokkaido (Japan); Kamiya, Y [Kanto Gakuin University, Yokohama (Japan)

    1996-10-27

    The storage tank is classified into a mixed type and stratified type. The stratified type is judged to be more advantageous from a viewpoint of the effective energy utilization. An experiment was made using a solar simulator to put the system, consisting of a vacuum double-glass tube collector and temperature selective storage tank, to practical use. The ejection position of the storage tank at the top is superior to that at the bottom, in the 60{degree}C layer of three layers (60, 40, and 20{degree}C). The ejection position hardly varies with the shape (straight or elbow) of an ejection port. When the temperature stratified layer is formed in two layers (40 {times} 2, 20{degree}C) to three layers (60, 40, and 20{degree}C), heat can be stably stored as the flow rate is higher. The stratified storage tank is inferior to the mixed storage tank in heat collection efficiency, but the specific exergy increases. By increasing the number of heat storage layers, the result of this experiment can also be applied to the linear temperature gradient layer obtained in the practical use. As a result of the above experiment, the basic data for an automated system design during practical application was obtained. 3 refs., 15 figs.

  20. Application of a temperature selective heat storage tank to a solar system. Part 3. Solar heat collecting system; Ondo sentaku chikunetsuso no solar system eno tekiyo. 3. Shunetsu hoshiki ni tsuite

    Energy Technology Data Exchange (ETDEWEB)

    Kamiya, Y [Kanto Gakuin University, Yokohama (Japan); Kanayama, K [Kitami Institute of Technology, Hokkaido (Japan)

    1996-10-27

    The tank system and tank-less system when the temperature selective heat storage tank is applied to a solar system were considered. In the tank system, the simulation shows that the annual supplementary heat consumption is reduced as the tank capacity becomes lower. The most suitable operating time set for determining the reference time is about five hours in winter and about nine hours in summer. The annual operating time is about 6.5 hours. In the tank-less system, the most suitable minimum flow rate per solar collector area of a heating medium in Tokyo and its districts is 10 L/hm{sup 2} for both three-step flow control and constant flow control. The tank-less system is slightly lower in annual supplementary heat consumption than the tank system. For the three-step flow control, a change in the annual supplementary heat consumption is lower than that in the minimum flow rate. For the constant flow control, however, the annual supplementary heat consumption rapidly increases when the flow rate more decreases than the optimum value. The number of pump start/stop counts for the three-step flow control is less than two times as high as for the constant flow control. 4 refs., 6 figs., 1 tab.

  1. Separation and purification of lactic acid. Thermal catalytic depolymerization of poly-lactic acid into lactide; Hakkoho nyusan no bunri seisei ni kansuru kenkyu. Pori nyusan no rakuchido eno sesshokuteki netsukai jugo

    Energy Technology Data Exchange (ETDEWEB)

    Morita, M.; Hirama, Y.; Liew, M. [Hokkaido National Industrial Research Institute, Sapporo (Japan)

    1996-05-10

    A new separation and purification method for lactic acid from fermentation broth is proposed by which poly-lactic acid produced from unpurified lactic acid is catalytically depolymerized into lactide fractions then further purified into lactide. In the present study, thermal depolymerization catalysts were investigated for commercial use. Iron catalysts, especially metallic iron, and ferrous oxide and lactate, were found to provide almost the same catalytic activity and lactide composition in depolymerization products and those in tin octoate and antimony oxide catalysts. Ferrous oxide was also applied to depolymerize poly-lactic acid derived form unpurified lactic acid to compare catalytic activity and lactide composition and was confirmed to show results similar to those of pure polymer. Based on these findings, it is concluded that iron catalysts can be used commercially. Furthermore, catalytic depolymerization of poly-lactic acids with different molecular weights were studied. Polymers with Mw 5,000-10,000 were found to be better for production of lactide, based on the behavior of depolymerization and lactide content in the product. 5 refs., 9 figs., 1 tab.

  2. Development of new technologies for high quality thin film and its application to energy engineering; Hikari seigyo to sokudo senbetsu ni yoru chokinshitsu usumaku no seisaku to energy bun`ya eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Hijikata, K; Inoue, T; Nagasaki, T; Suzuki, Y; Sato, I [Tokyo Institute of Technology, Tokyo (Japan); Nakabeppu, O [The University of Tokyo, Tokyo (Japan). Faculty of Engineering

    1997-02-01

    This paper describes laser irradiation and velocity selective deposition experiments for fabricating high quality thin films. For the formation of Ag thin film by vacuum deposition method, YAG laser was irradiated to atoms or clusters parallel or perpendicular to the NaCl single crystal substrate, to deposit them on the substrate. For another experiment, Ag atoms selected in the given velocity were deposited on the (001) NaCl substrate by passing the molecular beam through the velocity selector. When laser was not irradiated, the thin film showed a random structure. Epitaxial growth was accelerated by the laser irradiation. When the selective velocity was set in 353 m/s at the constant intensity of molecular beam, the diffraction pattern of the thin film showed net pattern. When the selective velocity was set in 529 m/s, a structure in which ring pattern was overlapped on the net pattern was obtained. 2 figs.

  3. Development of hydriding alloys with multi-functionally-graded properties and their applications to energy conversion devices; Keishagata fukugo kino wo hyomen ni motsu suiso kyuzo gokin no kaihatsu to energy henkan gijutsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Suda, S; Kadoma, H; Nagamoto, H; Okura, T [Kogakuin University, Tokyo (Japan)

    1997-02-01

    This paper describes the formation of fluoride layer on the surface of hydriding alloys. The fluoride formation reaction consists of a reduction removal process of surface oxide and a fluorination process. Specific surface area of alloy grains can be increased by the hydrogenation reaction in the surface layer accompanied with the removal of surface oxide, which results in easier permeation of molecular hydrogen into fluoride layer. During the fluorination process, a large amount of Ni in the alloy components is eluted, which results in the reduction of Ni distribution immediately under the fluoride layer in the alloy. Consequently, collector sites near the surface are reduced, and conductivity among alloy grains is degraded. To enhance the hydrogen collector sites, specific surface area of alloy grains can be increased by controlling the pH value of fluorination treatment solution in a given range. Moreover, performance of fluoride layer can be advanced by electrochemically dispersing metal Ni in the fluoride layer using Ni complex ion mixed in the treatment solution. 2 refs., 3 figs.

  4. Effect of sail on augmenting attitude stability of hovering VTOL vehicle supported by one-ducted-fan. Ductedter dot fan shiji VTOL ki no hover shisei anteisei eno ho no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Ando, S.; Kato, M. (Nagoya University, Nagoya (Japan). Faculty of Engineering)

    1991-07-05

    An analytical investigation was given on augmenting attitude stability of a VTOL airplane supported by one-ducted-fan, at hovering, by means of installing a sail having air resistance on a place higher than the vehicle center-of-gravity. Since the problem becomes nonlinear, the time-marching technique was used. The sail on which the emphasis was placed had an area of as less than several times as much of the duct sectional area, and a height of as less than several times as much of the duct diameter. The stabilization effect is expressed as {Delta}h = center of gravity height region providing the stability/duct diameter. Without a sail, {Delta}h was several percent, but with a sail, the value increased to about ten times as much. This increase in {Delta}h was remarkable in the direction that elevate the position of the center of gravity. More stability is obtained by increasing the sail height than by increasing the area. Substitutes to a sail, working on the same principle, could be a gas-bag and wind mill. A gas-bag, which can change its volume readily, will be able to vary the sail area easily. A wind mill could make the weight lighter than a sail, and has a possibility of varying the resistance through changing its blade pitch angle. 2 refs., 2 figs., 1 tab.

  5. Report on FS survey for project of introduction of highly energy-efficient trolley buses into the Mexico Metropolitan Area in FY 1997; 1997 nendo chosa hokokusho (Mexico city eno sho energy gata trolley bus donyu project FS chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Traffic jam and air pollution by automobiles are currently getting severe in the Mexico Metropolitan Area. Trolley buses were introduced for improving the environment more than ten years ago. Vehicles become too old for use, and their energy efficiency is low. In this project, 200 highly energy-efficient trolley buses are introduced to replace old inefficient trolley buses, which results in the improved traffic convenience in the City and enhanced energy efficiency. The new energy-efficient trolley buses are made of energy-efficient control VVVF inverters produced and exported by MELCO (Mitsubishi Electric Corporation), energy-efficient motors by MELMEX (Mitsubishi Electric Corporation, Mexico), and bodies by MASA which is a major manufacturer of bus bodies. The objective of this research is to analyze the background of introduction of new energy-efficient trolley buses and the effects of the present project. The results of analysis are going to be utilized for future promotion of the Joint Implementation and Clean Development Mechanism. 30 refs., 30 figs., 24 tabs.

  6. Desarrollo y aplicación de índices y simulaciones para la vigilancia y el pronóstico a mediano plazo del impacto del ENOS frente a la costa peruana

    OpenAIRE

    Quispe Ccalluari, Carlos; Tam Málaga, Jorge; Arrellano Rojas, Cinthia; Chamorro Gómez, Adolfo; Espinoza Morriberón, Dante; Romero Tadeo, Carlos; Ramos Flores, Jorge

    2017-01-01

    El propósito del trabajo es presentar índices oceanográficos del Pacifico Sudeste, pronósticos de la propagación de las ondas Kelvin ecuatoriales (OKE) y pronósticos del Índice Térmico Costero Peruano (ITCP), usando como un ejemplo la información observacional actualizada hasta setiembre 2016. Durante el trimestre julio-agosto-setiembre (JAS) 2016, los Índices Térmico Costero Peruano (ITCP) y del Anticiclón del Pacífico Sur (IAPS) presentaron condiciones neutras, el Índice del Áre...

  7. Preparation of Bi-Pb-Sr-Ca-Cu-O high Tc thick films on Ag or MgO substrate with superconductor paste; Bi kei ko Tc chodendo paste ni yoru Ag, MgO kibanjo eno atsumaku sakusei

    Energy Technology Data Exchange (ETDEWEB)

    Takabatake, N. [Ishikawa Technical High School, Ishikawa (Japan); Tsubota, T.; Ishikawa, T.; Ohashi, K. [Kanazawa Institute of Technology, Ishikawa (Japan)

    1995-07-15

    The following were reported on making Bi series superconducting thick films by a wet method. A paste was made by adding PSO (or ethanol solution of ethylenegrycol) of Yushiro Chemical Industry Co., Ltd. as a binder to a Bi series 2223 single-phase powder sample (blending composition Bi:Pb:Sr:Ca:Cu=1.8:0.4:2:2:3.2); the sample was then coated on an Ag (or MgO) substrate with a brush; after being dried at 105{degree}C for one hour, it was thermally decomposed at 700{degree}C for one hour; then, the process of prissurized forming (at pressure 2 to 5 ton f/cm{sup 2}) and of sintering at 845{degree}C for 20 hours or more were performed on the sample to form a thick film sample. A critical temperature Tc, critical current density Jc, etc., were measured on such thick film sample. As a result, nearly same values were obtained as Tc (93K) and Jc (84A/cm{sup 2}) which were those of a bulk sample made by using the same powder sample, pressurizing at 2 ton f/cm{sup 2} for pelletizing, and sintering at 845{degree}C for 20 hours. 6 refs., 7 figs., 1 tab.

  8. Příroda a domov : postřehy z pouště: domov je něco, co je na přírodě vyvzdorováno a odlišeno

    Czech Academy of Sciences Publication Activity Database

    Cílek, Václav

    2010-01-01

    Roč. 21, č. 23 (2010), s. 79-79 ISSN 0862-6545 Institutional research plan: CEZ:AV0Z30130516 Keywords : nature * desert * desert animals * nature a culture * man and nature Subject RIV: AC - Archeology, Anthropology, Ethnology

  9. enos tradičních hodnot Romů ve smíšených manželstvích romsko-českých

    OpenAIRE

    Innemanová, Petra

    2007-01-01

    The goal of my graduation treatise is research of three generations of mixed Romany-Czech marriages in the aspects of upbringing, education and traditions and how and how many of these aspects were transmitted in a progress of time. Which Romanian traditional values have kept during the theree genarations of the inter marriages. In the theoretical part of my treatise I tried to describe all topics which I then researched in the practical part with individual couples which were namely the fell...

  10. Bi-axial M-. Phi. analyses of RC columns using fiber model and comparison with experimental results. 2 jikumage wo ukeru hashirabuzai no M-. Phi. kankei eno fiber model no tekigosei

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, Y.; Tokuyama, S.; Furuichi, K. (Kajima Corp., Tokyo (Japan))

    1991-10-31

    In order to examine the accuracy of a fiber model for analyzing the stability of towers of a cable-stayed bridge subjected to biaxial bending force due to earthquake, experimental results of column test specimens were compared with analytical results. The relation between biaxial bending moment and curvature (M-{Phi}) was measured in biaxial bending model experiment using a reinforcement ratio, axial compressive force and loading pattern as parameters. Since the relation was greatly affected by axial modeling of a reinforcing material, the parameter analysis was conducted by paying particular attention to reinforcement models (bilinear model, cubic one and Ramberg-Osgood one). As a result, the Ramberg-Osgood model was suitable for columns with a large longitudinal reinforcement ratio and large axial tension such as seen in highrise buildings, while the cubic model was more suitable for columns with a small ratio such as seen in cable-stayed bridges. 4 refs., 10 figs., 1 tab.

  11. Energy-based damping evaluation of cable-stayed bridges and its application to Tsurumi Tsubasa bridge; Shachokyo shindo gensui no energy teki hyokaho to Tsurumi Tsubasakyo eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, H. [Saitama University, Saitama (Japan). Faculty of Engineering; Takano, H.; Ogasawara, M.; Shimosato, T. [Metropolitan Expressway Public Corp., Tokyo (Japan); Kato, M.; Kato, H. [NKK Corp., Tokyo (Japan)

    1996-07-21

    This paper provides and discusses a more common energy-based evaluation method of vibration damping in cable-stayed bridges. This method was applied to data obtained from the field vibration test of the Tsurumi Tsubasa Bridge. The damping was defined as dissipation energy in one cycle against the total potential energy. The dissipation energy from shoe friction, aerodynamic damping, and dampers for cables was added to the method proposed by Yamaguchi, et. al., in which the energy of girders, towers, and cables were quantitated, and the dissipation energy was determined from the loss factor of each constituent, to evaluate the damping of whole bridge. Thus, a more common energy-based evaluation method was provided. This method was applied to the damping obtained from the field vibration test of Tsurumi Tsubasa Bridge. Consequently, it was found that the damping of whole bridge was significantly affected by the shoe friction, aerodynamic damping, and dampers for cables. Distinguished damping characteristics of the Tsurumi Tsubasa Bridge could be explained by the energy-based evaluation. Validity of the energy-based evaluation method for damping of cable-stayed bridges was demonstrated. 15 refs., 9 figs., 6 tabs.

  12. Fracture mechanical modeling of brittle crack propagation and arrest of steel. 3. Application to duplex-type test; Kozai no zeisei kiretsu denpa teisi no rikigaku model. 3. Konseigata shiken eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Aihara, S; Tsuchida, Y [Nippon Steel Corp., Tokyo (Japan); Machida, S; Yoshinari, H [The University of Tokyo, Tokyo (Japan). Faculty of Engineering

    1997-12-31

    A proposal was made previously on a model of brittle crack propagation and arrest that considers the effect of crack opening suppression by using unbroken ligaments generated on steel plate surface and the effect that cracks precede in the central part of the plate thickness, based on a local limit stress theory for brittleness fracture. This paper discusses applicability of this model to a mixed type test, and elucidates causes for difference in the arrest tenacity of both types in a double tensile test of the standard size. The brittle crack propagation and arrest model based on the local limit stress theory was found applicable to a simulation of the mixed type test. Experimental crack propagation speed history and behavior of the arrest were reproduced nearly completely by using this model. When load stress is increased, the arrests in the mixed type test may be classified into arrests of both inside the steel plate and near the surface, cracks in the former position or arrest in the latter position, and rush of cracks into both positions. Furthermore, at higher stresses, the propagation speed drops once after cracks rushed into the test plate, but turns to a rise, leading to propagation and piercing. 8 refs., 15 figs., 3 tabs.

  13. Equivalent CTOD concept based on the local approach and its application to fracture performance evaluation of welded joints; Local approach ni motozuku toka CTOD gainen no teian to tsugite hakai seino hyoka eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ohata, M; Minami, F; Toyoda, M [Osaka University, Osaka (Japan). Faculty of Engineering; Tanaka, T; Arimochi, K [Sumitomo Metal Industries, Ltd., Osaka (Japan); Glover, A [Nova Gas Transmission Ltd., Calgary (Canada); North, T [University of Toronto (Canada)

    1997-12-31

    A proposal was given on an equivalent crack tip opening displacement (CTOD) concept which relates quantitatively fracture performance of a structural member with the result of a three-point bending CTOD test via the Weibull stress based on a local approach. The equivalent CTOD is defined as a CTOD in which a three-point CTOD test piece and a structural member provide the same Weibull stress. Experimental and analytical discussions were performed on X80 steel welded joints. Effectiveness of the equivalent CTOD concept was verified from the fact that the fracture performance in welded joints with a large width estimated from the result of the three-point bending CTOD test using the equivalent CTOD concept showed good correspondence with the fracture performance obtained in the experiments. On the other hand, the result of estimation using the conventional CTOD concept is considerably smaller than measurements. As an application of the equivalent CTOD concept, a new determination procedure was introduced on required fracture tenacity to ensure deformation performance required on structural elements. The required CTOD value shows a trend that the smaller the ratio of yield stress of the welded metals to that in the base material, the greater the required CTOD grows. 16 refs., 19 figs., 3 tabs.

  14. Ultimate strength analysis of thin plated structures using eigen-functions. 3rd Report. Application to reliability analysis; Koyu kansu wo mochiita usuita kozobutsu no dansosei kaisekiho. 3. Shinraisei kaiseki eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ueda, Y [Osaka University, Osaka (Japan). Welding Research Institute; Masaoka, K; Okada, H [University of Osaka Prefecture, Osaka (Japan). Faculty of Engineering

    1997-12-31

    A reliability analysis was performed on ultimate strength of a hull by introducing reliability engineerings into the idealized structural unit method. Elements developed under the present study were applied to a model of an actual structure to indicate that even an analysis requiring much time under the finite element method can be performed in a short time and at high accuracy when this method is used. Analysis acted with bending moment and shear force simultaneously was performed on a model used as a structure in experiments carried out by Nishihara, assuming pure bending moment and longitudinal strength during slamming. Then, a reliability analysis was conducted on the same model based on this analysis method to investigate the ultimate strength. In an analysis of an ultimate strength when bending and shearing that assume slamming act upon simultaneously, axial force in the hull side decreases as loading increases, wherein how the shearing force increases can be identified clearly. Although existence of initial bends reduces the strength, the effect of variance in the vicinity of the average value on the reliability is rather small, while the effect due to variance in yield stress is greater. 27 refs., 14 figs., 4 tabs.

  15. Fiscal 1997 report on the feasibility survey of Japan`s cooperation into energy/environment related fields in Asian countries; 1997 nendo chosa hokokusho (Asia shokoku ni okeru energy kankyo kanren bun`ya eno kyoryoku kanosei chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A survey was made to study possibilities of Japan`s cooperation in tackling energy/environment problems in Asian countries. In 1995 the GNP growth rate was 2.6% in the world, while it was 7.9% in Asia showing a rapid growth. With the accelerating industrialization and urbanization, energy demand is now over three times as much as that in the 1980s. This means increases in waste and environmental pollution. Especially, the use of firewood in non-electrified areas is a serious problem the same as the slash-and-burn farming and deforestation. Also relating to the production of electric power, it is inevitable to choose hydroelectric power and renewable energy in addition to fossil fuels. Therefore, the necessity is heightening of various technologies for it and environmental protection technologies such as coal cleaning. Local areas, where the population density is extremely low and the electrification cost is high, became victims of elecrification. There the power system should be shifted from the central supply system to the local distributed one. For it, it is necessary to recognize an importance of the distributed type renewable energy which is friendly to the environment. The paper outlined the state of each country and energy by policy and environment. 10 figs., 83 tabs.

  16. Report on achievements in fiscal 1991. Research and development of manganese nodule mining system (total system - experiment plan - edition/second of six volumes); 1991 nendo mangan dankai saiko system no kenkyu kaihatsu seika hokokusho. 2/6. Total system (jikken keikaku) hen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1992-06-01

    It is intended to research and develop a system for mining manganese nodules existing on deep ocean bottoms by using the fluid dredging system. A mining experimenting system will be developed, and fabricated on a trial basis to perform comprehensive ocean experiments, identify its performance, and collect different design data for a system to be used practically in the future. Fiscal 1991 has performed the following items: (1) detailed design on a comprehensive ocean experimenting device, and fabrication of part of the device, (2) preparation of experiment execution procedures for the comprehensive ocean experiment plan, and surveys on the experimenting ocean areas, (3) the comprehensive experiment simulation on behavior of the mine collecting device when settled on the ocean bottom, and strength of the ore lifting pipe considering safety, and (4) discussions on the basic plan for the mining system. The system under the research and development in progress is a system combining ore collection by water flow blow-up and suction, ore lifting by using a fluid dredge, and device towing. The ore collecting efficiency is defined as (nodule take-in quantity)/(take-in area in existence), whereas the water flow blow-up and suction system has greater advantage because of being simple in device configuration. The supply efficiency is defined as (nodule supply quantity to ore lifting device)/(nodule take-in quantity). Combination of the ore collection using the water flow blow-up and suction system with the ore lifting using the fluid dredge is a best selection. (NEDO)

  17. Survey of technological advancement of coal exploitation in Asia and Pacific for fiscal 1997. Formulation of production plans for model coal mines in China; 1997 nendo Asia Taiheiyo sekitan kaihatsu kodoka chosa. Chugoku ni okeru model tanko no seisan keikaku no sakutei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    In view of the prospective demand for coal in China and of the current state of transportation, a development plan is formulated for Tangkou Mining Area (of model mines) for the purpose of realizing efficient exploitation of coal. The infrastructures for coal transportation are complete in this area, and delivery of coal is easy from this area to the coal demanding regions. Although coal seams are quite deep in the ground, the important ones contain rich reserves. Exploitation is carried out under a vertical shaft scheme, in which pits extend horizontally at the level of 950m below the sea surface. As for production, an annual yield of 3-million ton is predicted thanks to two compositely mechanized coal faces. Coal is won by the monolayer side hole method in the case of seams not thicker than 4.0m, and by the caved stope method in the case not thinner than 4.0m. Employed for the mines are 1077 people. Operation days are 300, efficiency 15t/man/shift. The annual sale in total is expected to be worth 759-million 534.6-thousand yuan. To be required for the construction will be 1.2-billion yuan for mines and 0.2-billion yuan for coal dressing facilities, or 1.4-billion yuan in all, and the figures indicate that the plan is economically promising. 43 figs., 119 tabs.

  18. Achievement report for fiscal 1999 (edition B) on auxiliary New Sunshine Project. Development of coal hydrogasification technology (Research by using experimental device); 1999 nendo New Sunshine keikaku hojo jigyo seika hokokusho (B ban). Sekitan suiso tenka gaska gijutsu kaihatsu - Jikken sochi ni yoru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    With an objective of using practically the coal hydrogasification technology (the ARCH process), developmental research has been performed on important elementary technologies using different experimental devices. This paper summarizes the achievements in fiscal 1999. In the research by using a small testing apparatus, the Taiheiyo coal was used to have performed demonstration operation on the replacement natural maximized case, the heat efficiency maximized case, and the BTX maximized case. As a result, the three cases were found nearly as anticipated in the simulation, whereas the replacement natural gas maximized case has achieved the targeted whole coal conversion rate of 60% or more. However, the BTX maximized case presented a value lower than the targeted BTX yield of 12%. In the developmental research on the injector, the injector having been fabricated for the hot model test was given another combustion test, where the focal temperature of 1,200 degree C or higher was derived. The hot model test has verified the non-agglomeration performance of coal by using as parameters the focal temperatures, coal cross sectional area loads, coal types, and injectors. It was verified that the Taiheiyo and Shin Mu coals do not agglomerate excessively. (NEDO)

  19. New energy vision of Rokunohe Town. Maple green plan (Town creation using the riches of Nature and industries of the area); 2001 nendo Rokunohe machi chiiki shin energy vision. Meipuru Green keikaku - Yutaka na shizen to chiiki no sangyo wo ikashita machidukuri

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-02-01

    For the purpose of promoting the introduction of new energy and enhancing the awareness of it in Rokunohe Town, Aomori Prefecture, an investigational study was conducted of the state of energy supply/demand, existence amount of new energy, introduction of new energy, etc., and a vision was worked out. The population of Rokunohe Town was 10,481 according to the results of the national census taken in 2000, which is slightly decreasing. The energy consumption amount of the town is 16,063.6t in oil conversion, and the consumption depends on fossil fuels such as electric power, gasoline, light oil, heavy oil and LPG gas. For the action plan for introduction of new energy, the following were cited: field study of the photovoltaic power generation, preparation of the shopping street/school street which are safe and unfrozen (snow melting of sidewalk), potential study of the agricultural development of snow/ice energy, use of the agricultural waste such as animal feces and waste vegetable (study of introduction of small-scale bio-system), promotion of recycle of cooking oil (study of the use of clean energy vehicles for official vehicles and use of diesel substituting fuel), study of use of energy crops for the idle field, various education projects, etc. (NEDO)

  20. Fiscal 1997 report on the results of the New Sunshine Project subsidiary operation. Development of a geothermal water use power plant, etc. / technical development of the hot dry rock power generation system (development of electric technology); 1997 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (koon gantai hatsuden system no gijutsu kaihatsu (yoso gijutsu no kaihatsu))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    For the purpose of using hot dry rock energy to power generation, the R and D was continued of element technology of the hot dry rock power generation. In fiscal 1997, the construction of ground facilities, etc. for long-term circulation experiment was proceeded with to make data analysis for study of the experimental results. As for preparation for the long-term circulation experiment, design/fabrication/construction of experimental facilities were commenced, and review/fabrication of the monitoring system were conducted to strengthen the monitoring network of microearthquakes. In relation to the analytical research, using models connecting reservoirs and wells, relationships were studied among the distance between injection well and production well, production flow rate, and long-term thermal extraction characteristics of reservoirs. Further, to study structures of shallow/deep reservoirs at the Hijiori hot dry rock experimental field, re-determined were mechanism solutions of AE in deep hydraulic fracturing experiments, three well circulation tests, and preliminary circulation tests, and at the same time stress fields were studied. Fracture models were made and the simulation program was revised. 18 refs., 82 figs.

  1. FY 1998 'The New Sunshine Project' leading R and D. Report on the results of the leading R and D of supercritical fluid utilization technology; 1998 nendo 'New Sunshine Keikaku' sendo kenkyu kaihatsu. Chorinkai ryutai riyo gijutsu sendo kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The paper reported the FY 1998 achievement of the supercritical fluid utilization leading R and D which started in FY 1997 on a 3-year plan. In the R and D, solvolysis reaction, oxidation reaction and hydrogenation reaction were taken up in the chemical process using supercritical fluid. In the study of solvolysis reaction, the basic data were obtained on decomposition conditions of thermoplastic and thermosetting plastics in supercritical water. Further, concerning the synthesis of environmental friendly type carbonate using CO2, a conversion rate of almost 100% was obtained. About the oxidation reaction, conditions were found out for burning low grade coal in supercritical water without emitting acid gas. This is considered to lead to a possibility of the supercritical water power generation. Relating to the hydrogenation reaction, a study was made on lightening technology of heavy distillate using supercritical water, and the conditions for effective emission of methane and hydrogen were found out. As to the base technology, a study was made of metal materials with high corrosion resistance against supercritical water. (NEDO)

  2. FY 1998 'The New Sunshine Project' leading R and D. Report on the results of the leading R and D of supercritical fluid utilization technology; 1998 nendo 'New Sunshine Keikaku' sendo kenkyu kaihatsu. Chorinkai ryutai riyo gijutsu sendo kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The paper reported the FY 1998 achievement of the supercritical fluid utilization leading R and D which started in FY 1997 on a 3-year plan. In the R and D, solvolysis reaction, oxidation reaction and hydrogenation reaction were taken up in the chemical process using supercritical fluid. In the study of solvolysis reaction, the basic data were obtained on decomposition conditions of thermoplastic and thermosetting plastics in supercritical water. Further, concerning the synthesis of environmental friendly type carbonate using CO2, a conversion rate of almost 100% was obtained. About the oxidation reaction, conditions were found out for burning low grade coal in supercritical water without emitting acid gas. This is considered to lead to a possibility of the supercritical water power generation. Relating to the hydrogenation reaction, a study was made on lightening technology of heavy distillate using supercritical water, and the conditions for effective emission of methane and hydrogen were found out. As to the base technology, a study was made of metal materials with high corrosion resistance against supercritical water. (NEDO)

  3. Report on research and development achievements in fiscal 1979 in Sunshine Project for geothermal water utilizing power plants. Separate volume of surveys and studies on plant development plans (Surveys on trends in overseas technologies); 1979 nendo chinetsu nessui riyo hatsuden plant no kenkyu kaihatsu seika hokokusho (plant kaihatsu keikaku chosa kenkyu). Bessatsu (Kaigai gijutsu doko chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1980-03-01

    This paper describes surveys on trends in overseas technologies in development plans for geothermal water utilizing power plants. In heat cycles, the binary and two-stage flash cycles were analyzed by using a generalized equation of state, and theses on optimizing working fluid properties and cycle conditions with maximum thermal efficiency were described. Theses that were described include those for criteria to select working fluids and thermal power cycles against the binary cycle using a heat source at 104 to 204 degree C. The binary cycle working fluid was found better in mixed systems than in pure systems as seen from process and economic performance. The paper introduces a heat conductivity experimenting device and data required for designing a heat exchanger. It also describes the Heber geothermal experimental plant to demonstrate reasonability of assumed working media. A fluidized bed type and a shell tube type were applied to heat exchangers at the Raft River 50 MW geothermal power plant for comparison and discussion. Fouling factor was also estimated. A discussion was given on fluidity distribution of a fluidized bed heat exchanger. Design of a heat discharge system is important for geothermal power generation because heat source temperatures are so low that more than 85% of heat that has been taken in is discharged. The paper also describes turbines and other facilities. (NEDO)

  4. FY 2000 report on the results of the development of technology for commercialization of the photovoltaic power system - R and D of evaluation technology of the photovoltaic power system. R and D of the solar cell evaluation system; 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyodenchi hyoka gijutsu no kenkyu kaihatsu - Taiyodenchi hyoka system no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Study was made of the development of the basic technology for the integrated evaluation of solar cell performance, grasp of degradation phenomena of solar cell modules by outdoor exposure test, development of the accelerated degradation test method, etc., and the FY 2000 results were summed up. As to the development of the ultra-high approximation solar simulator for cell evaluation, a simulator was fabricated of which the irradiation non-uniformity is {+-} 1.0% and the spectral agreement is within {+-} 10% in 10 wavebands out of the 16 wavebands. Relating to the development of evaluation technology of large area modules, performance of the spectral irradiance distribution, etc. was improved by modification of the solar simulator, which made accurate measurement possible. In the study of degradation of solar cell modules, exposure tests on various kinds of solar cell modules were continued at 5 sites in Japan, 3 sites in Australia and 1 site in Oman for data collection/analysis. Further, analysis was made of Isc changes in the early stage of exposure, phenomenon of cell's cloudy discoloration, degradation caused by increase in series resistance, etc. As the test method of light accelerated degradation of A-Si solar cell, a brightness cycle test method was developed. (NEDO)

  5. FY 1990 report on the R and D of the manganese nodule mining system. 2/6 volume. Total system (experimental plan); 1990 nendo mangan dankai saiko system no kenkyu kaihatsu seika hokokusho. 2/6. Total system (jikken keikaku) hen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-03-01

    For the purpose of securing the stable supply of non-ferrous metal resources such as Ni, Co, Cu and Mn and of improving the overall ocean development technology, the R and D were carried out of a technology to mine Mn nodules existing in the bottom of deep sea of the depth between 4,000m and 6,000m by the fluid dredging method which is highly efficient and reliable. Therefore, plans of experiments to be made for each subsystem are adjusted/integrated to make the contents of a comprehensive experiment, and at the same time a draft of the comprehensive experiment plan was worked out for an experimental system to be developed/trially fabricated. As to a total system (experimental plan), a plan for execution was studied in the case of rationalizing the comprehensive ocean experiment plan and choosing between pump lift and air lift. The TA-C sea area was continuously investigated as a candidate sea area for survey and the range was limited. The paper studied the basic plan of the mining system and commenced the basic study of the assessment of economical efficiency. (NEDO)

  6. Achievement report for fiscal 1999 on auxiliary New Sunshine Project. Development of coal hydrogasification technology (Survey and research on its social acceptability); 1999 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu - Shakai tekigo sei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    With an objective to evaluate feasibility of practical use and economy of the coal hydrogasification technology (the ARCH process), survey and research have been performed. This paper summarizes the achievements in fiscal 1999. In the survey on the social acceptability, survey has been made on the future trend in the demand and supply and the price of LNG, LPG, and coal for hydrogasification. As a result, it was discovered that the price of LNG imported into Japan is determined as if linked with the crude oil price, and Saudi Arabia is the price leader of the LPG price. With respect to the survey on the possibility of international cooperation, surveys were conducted on the prospects of the long-term demand and supply in China, natural gas resources, and the demand and supply thereof. The feasibility study has estimated the product gas manufacturing cost after the process has been improved. In the trial calculation on the three-mode cost, it was discovered that, although the profit from byproducts is great, the BTX maximized mode causes the manufacturing cost to be higher by as much as 2 to 3 yen per Nm{sup 3} than that of other modes because of higher unit consumption in raw materials and higher construction cost. (NEDO)

  7. International Clean Energy System Using Hydrogen Conversion (WE-NET). subtask 1. Research study on integrated evaluation and development plan; Suiso riyo kokusai clean energy system gijutsu (WE-NET). subtask 1. Sogo hyoka to kaihatsu keikaku no tame no chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    This paper describes the research result on the WE-NET project in fiscal 1996. The WE-NET project is composed of various elemental technologies such as hydrogen production, transport, storage, low-temperature material, utilization and hydrogen combustion turbine. The organic integrated cooperation and coordination between individual subtasks are indispensable for effective promotion of the project and optimization of the total system. The current R and D states of every elemental technology were surveyed, and its findings were utilized for coordination of the whole project and examination of the research project including pilot studies. Eleven important items in the total coordination including a total system cost and safety measures in a developmental stage were examined. The development results for 4 years of fiscal 1993-1996 were assessed together, and the draft working plan for fiscal 1997-1998 was also decided. The verification test plan of a hydrogen combustion turbine scheduled in Phase II was studied, and the basic plans of development step were proposed. The draft report of a transition scenario was also prepared. 6 figs., 68 tabs.

  8. Achievement report for fiscal 1997 (edition B) on auxiliary New Sunshine Project. Development of coal hydrogasification technology (Research by using experimental device); 1997 nendo New Sunshine keikaku hojo jigyo seika hokokusho (B ban). Sekitan suiso tenka gaska gijutsu kaihatsu - Jikken sochi ni yoru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    With an objective of using practically the coal hydrogasification technology (the ARCH process), developmental research has been performed. This paper summarizes the achievements in fiscal 1997. In the research by using a small testing device, the Taiheiyo coal was used to have derived hydrogasification data (distribution and yield of the reaction products) in case of having changed the temperature, residential time and H{sub 2}/caoal ratio at a pressure of 7.0 MPa. In the developmental research on the injector, a test to verify mixing performance was performed by simulating the coal/hydrogen with gas/gas and coal/gas at normal temperature and pressure. Furthermore, discussions were given on the heat conduction analysis and cooling structure, whereas an injector was designed and fabricated. With respect to the hot model test to verify the performance of the injector, detailed design and partial fabrication of the test device were carried out. In addition, development was conducted on the coal/gas system mixing simulation to simulate the states of dispersion and mixing of the coal as the first phase of developing the mixing and temperature rise simulation. (NEDO)

  9. FY 2000 report on the results of the development of technology for commercialization of the photovoltaic power system - R and D of evaluation technology of the photovoltaic power system. R and D of the system evaluation technology; 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyoko hatsuden system hyoka gijutsu no kenkyu kaihatsu - System hyoka gijutsu no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Based on the evaluation method for the performance prediction system of the standard photovoltaic power system, the R and D were conducted of the system generation output prediction technology which is general-purpose, simplified and applicable to various kinds of photovoltaic power system for residential use, and the FY 2000 results were summed up. In this fiscal year, the photovoltaic power system for residential use was increasingly installed at 15 places, and 100 sites in total were made database and analyzed. As to the development of simulation technology, technology of calculation was established such as the simulation of multi-plane array composition and correction of multi-plane array incidence. Further, technical information on system trouble and knowledge/information/proposal for reducing power generation loss were arranged by design parameter. Using the data on solar radiation/power loss at sites of residential use photovoltaic power systems installed in the Kanto area, value analysis of the capacity of wide area facilities of the photovoltaic power system was made by the statistical method. This study was compiled into the revised edition of design manual. (NEDO)

  10. FY 2000 report on the results of the development of commercialization technology of the photovoltaic power system. Demonstrative study of the photovoltaic power system (Study of the high density connection technology); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyoko hatsuden system no jissho kenkyu (Komitsudo renkei gijutsu no kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the photovoltaic power system connected to the distribution line in high density, study was made in terms of the power quality, elucidation of the effect on operation/protection of the distribution line and the measures to be taken, improvement of power quality using inverter, etc., and the FY 2000 results were summed up. In this fiscal year, the results of the research made in four years were arranged, and at the same time, the theoretical analysis, verification test, etc. that were necessary for summarization of the research results were carried out. As to various kinds of technology for the measures to be taken, the following were conducted: study of the effect on the rise in voltage of the distribution line, development of the dispersed control type voltage stabilization method, test on characteristics of individual operation of the inverter on the market, simulation analysis of characteristics of the continuous individual operation, development of the high reliability individual operation prevention method, verification study of the environmental adaptability, etc. As a technology for improving utility value of the photovoltaic power generation, a high function inverter was developed which conducts not only the dc-ac conversion, but the smoothing of generating output/load variations and load higher harmonics/reactive power compensation. At the Rokko testing facilities, test was made of the parallel operation (5 units) of the pole transformer. (NEDO)

  11. FY 2000 report on the results of the development of technology for commercialization of the photovoltaic power system - R and D of evaluation technology of the photovoltaic power system. R and D of the solar cell evaluation system; 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyodenchi hyoka gijutsu no kenkyu kaihatsu - Taiyodenchi hyoka system no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Study was made of the development of the basic technology for the integrated evaluation of solar cell performance, grasp of degradation phenomena of solar cell modules by outdoor exposure test, development of the accelerated degradation test method, etc., and the FY 2000 results were summed up. As to the development of the ultra-high approximation solar simulator for cell evaluation, a simulator was fabricated of which the irradiation non-uniformity is {+-} 1.0% and the spectral agreement is within {+-} 10% in 10 wavebands out of the 16 wavebands. Relating to the development of evaluation technology of large area modules, performance of the spectral irradiance distribution, etc. was improved by modification of the solar simulator, which made accurate measurement possible. In the study of degradation of solar cell modules, exposure tests on various kinds of solar cell modules were continued at 5 sites in Japan, 3 sites in Australia and 1 site in Oman for data collection/analysis. Further, analysis was made of Isc changes in the early stage of exposure, phenomenon of cell's cloudy discoloration, degradation caused by increase in series resistance, etc. As the test method of light accelerated degradation of A-Si solar cell, a brightness cycle test method was developed. (NEDO)

  12. New Sunshine Program for Fiscal 2000. International cooperative project for developing photovoltaic power system practicalization technology (International Energy Agency (IEA)/Cooperative Program on Photovoltaic Power Systems (PVPS) implementing agreement - Executive committee meeting); 2000 nendo New sunshine keikaku. Taiyoko hatsuden system jitsuyoka gijustu kaihatsu kokusai kyoryoku jigyo (IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei shikko iinkai)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Cooperative endeavors of research and development, verification, analysis, information exchange, introduction acceleration, etc., were exerted through participation in the above-said PVPS program. At the 15th PVPS executive committee meeting held in this fiscal year, reconsideration was made about the commencement of new tasks, change of OAs (operating agents), change of participating countries, etc., whose current state was not correctly reflected in the existing implementation agreement. At the 16th PVPS executive committee meeting, discussions were made and conclusions were reached that the next executive committee meeting decide whether to change the chairman, that deliberation be made in 2003 to decide whether to hold the 4th IEA/PVPS executive conference in Japan, that the assessment of each of the tasks be carried out in fiscal 2001, and that Task I conduct studies about market implementation for the fruits of the research-centered activities in the past to hit the market, etc. Workshop meetings were held, where Australia, France, Italy, and Japan reported their PVPS research, development, and popularization efforts. (NEDO)

  13. Reports on 1977 result of research. Investigation for selecting site location of pilot plant for 7,000Nm{sup 3}/day class high calorie gasification; 1977 nendo sunshine keikaku ni kakawaru plant kenkyu kaihatsu seika hokoku. 7,000Nm{sup 3}/nichi kyu kokarori gas ka pilot plant yochi no ricchi sentei chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1978-03-20

    A report was made on the result of investigation for selecting a suitable site for a coal gasification pilot plant. The high calorie gasification plant under the Sunshine Project is scheduled to have a parallel operation of two methods. It could be decided on one only method depending on the future studies. One is the 'water gasification method' using coal only as the raw material, with hydrogen gas added to contrive methanization. The other is the 'hybrid gasification method' using mixed slurry of powdered coal and heavy oil as the raw material, with oxygen supplied to it to form a clean gas. The sites proposed for the pilot plant are the cities of Yubari, Iwaki, Kita-Ibaraki, Tagawa, Iizuka and Imari. The items for assessment of cost effectiveness are the expenses of development of a site, road construction, removal of existing obstacles, plant construction, power receiving equipment construction, irrigation supply facilities construction, wastewater treatment system construction, ash discharging system construction, transportation, and supply/processing-related maintenance. As a result of the assessment, Iwaki city was picked up as the area almost free from drawbacks to cost effectiveness. (NEDO)

  14. FY 2000 report on the results of the development of commercialization technology of the photovoltaic power system. International cooperation project (IEA photovoltaic power generation program - Collection of the information on Task IX); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu kokusai jigyo kyoryoku (IEA taiyoko hatsuden program task IX ni kansuru joho shushu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Based on 'the Implementing agreement for a research cooperation project on the photovoltaic power system' being promoted by IEA, collection of the information was made on Task IX: Promotion of the effective spread of the PV technology in developing countries, and the FY 2000 results were summarized. In Task IX, for technical/economic subjects in introducing the PV system to developing countries, a commendable/practical guide using the experiences having been gained was to be arranged. Also, workshop was to be opened in developing countries as model, and cooperation was to be promoted with international organizations such as the Bank of the World. In this fiscal year, two meetings of specialists (abroad) and four sectional meetings of operation (in Japan) were held. This fiscal year was the second year of the 5-year plan. The standard for selecting developing countries as model was studied, and a draft of the commendable/practical guide was made and discussed in the meeting of specialists. (NEDO)

  15. FY 2000 report on the results of the development of commercialization technology of the photovoltaic power system. International cooperation project (IEA photovoltaic power generation program - Collection of the information on Task IX); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu kokusai jigyo kyoryoku (IEA taiyoko hatsuden program task IX ni kansuru joho shushu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Based on 'the Implementing agreement for a research cooperation project on the photovoltaic power system' being promoted by IEA, collection of the information was made on Task IX: Promotion of the effective spread of the PV technology in developing countries, and the FY 2000 results were summarized. In Task IX, for technical/economic subjects in introducing the PV system to developing countries, a commendable/practical guide using the experiences having been gained was to be arranged. Also, workshop was to be opened in developing countries as model, and cooperation was to be promoted with international organizations such as the Bank of the World. In this fiscal year, two meetings of specialists (abroad) and four sectional meetings of operation (in Japan) were held. This fiscal year was the second year of the 5-year plan. The standard for selecting developing countries as model was studied, and a draft of the commendable/practical guide was made and discussed in the meeting of specialists. (NEDO)

  16. New Sunshine Program for Fiscal 2000. International cooperative project for developing photovoltaic power system practicalization technology (International Energy Agency (IEA)/Cooperative Program on Photovoltaic Power Systems (PVPS) implementing agreement - Task 1); 2000 nendo New sunshine keikaku. Taiyoko hatsuden system jitsuyoka gijustu kaihatsu kokusai kyoryoku jigyo (IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei task 1)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Fiscal 2000 participation in the above-named program is reported. At the Task 1 meeting of experts, electric power application in the participating countries was taken up and information was exchanged concerning the technical, economical, and environmental facets of photovoltaic power generation, efforts were made to disseminate the technology to non-participating countries, and coordination was established between the Tasks. For the preparation and publication of the ISR (International Survey Report), Japan would prepare and submit its NSR (National Survey Report) on Japan's photovoltaics-related policies, amounts of introduction and production, etc. The ISR was to be compiled by technical writers based on the NSRs submitted by the countries involved, to be bound into a book by September after supervision by the Task 1 staff and the executive committee. As for Market Implementation, it would be compiled under the leadership of Germany, Sweden, Denmark, Norway, and Japan. An added-value workshop was held at Glasgow, the United Kingdom, in May 2000 with the participation of 53 representing 14 countries. (NEDO)

  17. Report on fiscal 1996 basic survey project for efficient use of energy in developing countries - database building project. Part 2. Decision on data base dissemination plan; 1996 nendo hatten tojokoku energy koritsuka kiso chosa jigyo (database kochiku jigyo) hokokusho. 2. Database no fukyu keikaku no sakutei

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A dissemination plan was decided on concerning an energy-related database, which has been prepared in the eight countries including Japan in the Asian Pacific region since fiscal 1993. The database is so designed that the energy-related data of the eight countries are retained equally by each country and that the data of all these countries are readily made available in each of these counties in the same manner as retrieving the data of its own. It is necessary that each country establishes a system of amassing data of its own and collecting the data continuously as well as renewing the data mutually with the other countries. The disseminating/enlightening measures of the database were extracted from such viewpoints as enhancing the recognition level, educating/enlightening the usage, teaching the operation method, and customizing the NEDO-DB. In addition, a plan was prepared in which organizations/institutions, as the object of the dissemination and enlightenment in each country, were classified into four groups based on the relation to their counterpart and on the possibility of the database utilization, with a schedule made for each group as to the implementation of each of the disseminating/enlightening measures. (NEDO)

  18. Report on the results of the FY 1998 hydrogen utilization international clean energy system technology (WE-NET). Subtask 1. Survey/research for the comprehensive evaluation and developmental plan; 1998 nendo suiso riyo kokusai clean energy system gijutsu (WE-NET). 1. Sogo hyoka to kaihatsu keikaku no tame no chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The paper described the results of the FY 1998 WE-NET project survey. WE-NET is composed of various element technologies such as hydrogen production, hydrogen transportation, storage technology, low-temperature materials, hydrogen utilization, and hydrogen combustion turbine technology. Therefore, considering the effectiveness as a total system, it is extremely important to traversally evaluate the situation of the R and D of each technology and developmental achievements and to work out developmental plans with integration, considering the effectiveness as a total system. From viewpoints of making effective promotion of the project and attempting optimization as a total system, it is necessary to make organic/comprehensive connection and adjustment among individual subtasks all the time. In this survey/research, in the case of proceeding with the above-mentioned studies, a committee having knowledgeable persons and learned persons as members was established. There, an investigational study was conducted over the whole WE-NET structural technology, and at the same time the following were attempted: the constant/mobile comprehensive adjustment of the whole project, evaluation of the developmental results, and optimization of the developmental plans. The results obtained in 6 years of Period I were evaluated traversally and comprehensively, and how to proceed with the development in Period II was proposed, which showed the developmental continuity. (NEDO)

  19. Achievement report for fiscal 1997 (New Sunshine Project) on the development of superconductor power application technology. Research on a total system / investigative research on introduction effects; 1997 nendo chodendo denryoku oyo gijutsu kaihatsu (New Sunshine keikaku) seika hokokusho. Total system nado no kenkyu / donyu koka no chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    This paper describes investigation and discussion on effects of introducing a superconductor power application technology. The generator sub-committee has compared features, technical problems and development expenses in the first and second proposals, but has not reached the final conclusion. The first proposal is targeted for early realization of 200-300 MW class generators with development cost of six to seven billion yen and a development term of seven years. These developments raise largely towards practical application the levels of material technologies, fabrication and processing technologies, and analysis and design technologies. The second proposal is intended of developing 200-300 MW class generators targeted for increased diameter, as a reduced size machine of a 600-MW generator being a future generator. It will take development cost of eight to nine billion yen with the period of nine years for the development. Majority of the technologies required for developing the future 600-MW class generator can be demonstrated. The AC superconductor device sub-committee has investigated design examples, clarified the specification requirements, and investigated and studied the development measures. The oxide superconductor sub-committee has investigated and studied making wires and conductors, and device application feasibility, but has not reached the stage of presenting specific research and development methods. The practical application strategy sub-committee has also not been able to present a collective measure because of difficulty of making future prospect on the electric power business. (NEDO)

  20. FY 2000 report on the plan to carry out a model project for recovery of waste heat from the cement sintering equipment in India and the survey of the feasibility; 2000 nendo Indo ni okeru cement shosei setsubi hainetsu kaishu model jigyo jisshi keikaku oyobi fukyu kanosei chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of conserving energy and reducing greenhouse effect gas emission, survey was conducted on a project for recovering waste heat from the cement production process and using it for power generation in India. In India, the production amount of cement has steadily been increasing in and after the complete liberalization of the cement industry in 1989, and now the production amount is second in the world. Duties of approximately 25% are imposed on the import of the cement waste heat equipment, which is still a high-rate tariff. The India Cement Co., which is a candidate local company for this project, is a typical cement company in an excellent financial state in India. As to the economical efficiency of the project, economical effects are very good as seen in the internal earning rate of more than 30% and the period of ROI of less than 4 years, even if high-rate duties of India are imposed. There seems to be a great possibility of the spread of the related technology in the light of the following reasons: the situation of electric power in India is not good, reduction in production cost is being urgently requested due to the drop in cement price, and the equipment in this project is clean equipment using waste heat and therefore meets with the policy of the Indian government in which emphasis is placed on the environment. (NEDO)

  1. Report on results of feasibility study in fiscal 1986 on use of coal in next generation high efficiency power generation system - research commissioned by Moonlight project propulsion room of Agency of Industrial Science and Technology. MHD generation subcommittee; 1986 nendo jisedai kokoritsu hatsuden system no sekitan gas riyo feasibility chosa kenkyu seika hokokusho (Kogyo Gijutsuin Moonlight keikaku suishinshitsu itaku chosa). MHD hatsuden bunkakai

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-03-01

    A research study was done on MHD generation by coal gasificating combustion. MHD generation is a very attractive power generation system such that efficiency is as high as 55%, that preservation of the environment is superior, and that coal can be used as fuel. The open cycle seems suitable for a one million kW class as a base load following up load fluctuation of approximately 20%, while the closed cycle for 200-300 thousand kW class doing daily start-stop. With a mind to a scale of 30 MWt, in the open cycle, R and D is required in such items as a coal gas combustor, generation channel, high temperature air heater, and seed/slag recovery device. In the closed cycle, R and D is required in the generation channel, high temperature helium heater/high temperature valve, seed injection/recovery device, operation technique of helium closed loop, etc.. Moreover, as a total system, development is necessary in the areas of conceptual design and optimization method, partial load operation and DSS operation method, for example. (NEDO)

  2. Basic investigation on promotion of joint implementation in fiscal 2000. Energy saving program for the Sao Paulo State Primary Schools in the Federative Republic of Brazil; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Brazil Renpo Kyowakoku Sao Paulo shuritsu shoto gakko no sho energy keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    With an objective of saving energy and reducing greenhouse gas emission, discussions have been given on improvement measures for lighting equipment in the Sao Paulo State Primary Schools in the Federative Republic of Brazil. Measures for the energy saving are composed of modification to high-efficiency lighting equipment using electronic ballasts, high-efficiency fluorescent lamps, and reflectors, and introduction of control systems using lighting control sensors. In the survey, taking up 3,000 schools as the objects of implementation, a project scheme was established that the energy saving measures will be introduced, and the investment cost will be recovered by concluding the ESCO service for five years, after which the school side enjoys the profit for five years. As a result of the discussions, the total project cost will amount to 2.82 billion yen, with which the energy saving quantity would be 7,636 tons annually as converted to crude oil, or 114,540 tons during a period of 15 years as the achievement of the project as a whole. Greenhouse gas emission would be reduced by 7,397 t-CO2 on an annual average, or 110,949 t-CO2 in the project as a whole. Discussions on the profitability revealed that the internal profit rate can be calculated as 15.73%, indicating that the profitability can be envisaged. (NEDO)

  3. Results of the supplementary work to the fiscal 1994 New Sunshine Project. Development of geothermal power plants, etc. (development of production, technology for deep-seated geothermal resources); 1994 nendo new sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant to kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu shinbu chinetsu shigen seisan gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    The paper reports on the fiscal 1994 results of the study of the development of a technology for collecting deep-seated geothermal resources, which has been made for increasing the capacity of the geothermal power generation as a part of the New Sunshine Project. As a plan for the development, a development is made of logging equipment and its auxiliary system and then characteristics of the deep-seated geothermal well are clarified. The logging equipment is a PTSD (pressure/temperature/spinner flow-meter/fluid density) logger which stands the use at deep-seated geothermal wells of 400{degree}C and 490 kgf/cm{sup 2} and measures pressure, temperature, flow rate and fluid density under static and dynamic conditions. In this fiscal year, metal seals were developed for preventing geothermal fluids from penetrating into the PT probe. Qualities and inner/outer diameters of various kinds of structural materials used in the S probe were determined, and output necessary enough to detect the rotation number is obtained. Measuring precision of D logging by {gamma} rays was evaluated. The study was made of the monitoring technology including the borehole and ground measuring system, the borehole fluid sampling and the scale formation. Relating to the tracer widely used in monitoring of hydrothermal reservoirs, investigated was the trend of the technology from abroad. 8 refs., 60 figs., 26 tabs.

  4. Report on New Sunshine Program-supported undertakings for fiscal 1995. Development of hot water power plant and deep-seated geothermal resources sampling/exploiting technologies; 1995 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu, shinbu chinetsu shigen seisan gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Reported are the results of researches conducted in fiscal 1995. For the formulation of a general development design, data are collected about domestic high-temperature thermal wells through questionnaires and literature probing, and are scrutinized. As for the development of logging technology, a memory type PT (Pressure, Temperature) logger is experimentally constructed, and is found to properly operate in an environment of up to 350degC in a production well. An experimentally manufactured S-probe proves to be capable of heat insulation and sealing. In the field of PT monitoring, a high-temperature optical fiber is experimentally fabricated for study, capable of measuring temperatures up to 400degC. As for the development of high-temperature tracer monitoring technology, basic experiments are conducted about the thermal characteristics of aromatic acids, and preparatory experiments about gas phase tracers. In the study of scale monitoring technology, deep-seated fluids are collected and analyzed. In the field of production control, technical problems are discussed and information is gathered centering on methods for scale prevention and removal. 31 refs., 90 figs., 40 tabs.

  5. New Sunshine Program for Fiscal 2000. International cooperative project for developing photovoltaic power system practicalization technology (International Energy Agency (IEA)/Cooperative Program on Photovoltaic Power Systems (PVPS) implementing agreement - Task 1); 2000 nendo New sunshine keikaku. Taiyoko hatsuden system jitsuyoka gijustu kaihatsu kokusai kyoryoku jigyo (IEA taiyoko hatsuden system kenkyu kyoryoku program jisshi kyotei task 1)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Fiscal 2000 participation in the above-named program is reported. At the Task 1 meeting of experts, electric power application in the participating countries was taken up and information was exchanged concerning the technical, economical, and environmental facets of photovoltaic power generation, efforts were made to disseminate the technology to non-participating countries, and coordination was established between the Tasks. For the preparation and publication of the ISR (International Survey Report), Japan would prepare and submit its NSR (National Survey Report) on Japan's photovoltaics-related policies, amounts of introduction and production, etc. The ISR was to be compiled by technical writers based on the NSRs submitted by the countries involved, to be bound into a book by September after supervision by the Task 1 staff and the executive committee. As for Market Implementation, it would be compiled under the leadership of Germany, Sweden, Denmark, Norway, and Japan. An added-value workshop was held at Glasgow, the United Kingdom, in May 2000 with the participation of 53 representing 14 countries. (NEDO)

  6. FY 2000 report on the results of the development of commercialization technology of the photovoltaic power system. International cooperation project (Collection of the information on the IEA photovoltaic power generation program); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu kokusai jigyo kyoryoku (IEA taiyoko hatsuden program ni kansuru joho shushu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Based on 'the Implementing agreement for a research cooperation project on the photovoltaic power system' being promoted by IEA, collection of the information on the photovoltaic power system was made, and the FY 2000 results were summarized. In Task I: Exchange of the information on the photovoltaic power system and the spread, the final report on 'the study on added values of PV system' was made. In Task II: Operational performance and design of the photovoltaic power system and subsystem, specifications for new database were determined, and the existing data were checked/revised/added. In Task III: Design and operation of the stand-alone type and remote island use photovoltaic power plant, survey was conducted of the present situation of technical standards and quality guarantee. In Task 7: Photovoltaic power system integrated with construction materials, work was done for making a book of installation samples of the PV system integrated with construction materials in each country. In Task 8: Investigative study of possibilities of the large-scale photovoltaic power generation using the unused land such as desert, a report making of the secondary survey was started. (NEDO)

  7. FY 1993 report on the results of the subsidy project for the Sunshine Project. Development of coal use hydrogen production technology (Support study of pilot plant - Trial development of materials of plant use equipment); 1993 nendo Sunshine keikaku hojo jigyo seika hokokusho. Sekitan riyo suiso seizo gijutsu kaihatsu - Pilot plant no shien kenkyu (Plant yo kiki zairyo no shisaku kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    As to the development of coal use hydrogen production technology, the paper made the test study on the improvement of gasifier use materials and evaluation of the characteristics, the evaluation test in the environment using the actual machine, etc., and the FY 1993 results were reported. The results of the study were as follows. Concerning the shaped refractory for gasifier hearth, it was found that high chromia base and picrochromite base refractory development materials had much more excellent coal slag resistance than other existing component-system materials. It was shown that the development materials began to deteriorate under the coal gasification environment at temperatures of about 1,500 degrees C or higher. As to the mullite ceramics, a possibility was shown of improving the slag permeation resistance by making the crystal grain coarse by long-time sintering. By the survey of the state of damage of the proposed materials (refractory and iridium) used in the operational environment of the pilot plant, the outlook for use limit was made clear. In the environment test using the actual machine on the proposed metal base alloy of the typical equipment of the pilot plant, the correspondence between the operational environment and material corrosion was made clear. (NEDO)

  8. FY 2000 report on the results of the development of commercialization technology of the photovoltaic power system. International cooperation project (Collection of the information on the IEA photovoltaic power generation program); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu kokusai jigyo kyoryoku (IEA taiyoko hatsuden program ni kansuru joho shushu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Based on 'the Implementing agreement for a research cooperation project on the photovoltaic power system' being promoted by IEA, collection of the information on the photovoltaic power system was made, and the FY 2000 results were summarized. In Task I: Exchange of the information on the photovoltaic power system and the spread, the final report on 'the study on added values of PV system' was made. In Task II: Operational performance and design of the photovoltaic power system and subsystem, specifications for new database were determined, and the existing data were checked/revised/added. In Task III: Design and operation of the stand-alone type and remote island use photovoltaic power plant, survey was conducted of the present situation of technical standards and quality guarantee. In Task 7: Photovoltaic power system integrated with construction materials, work was done for making a book of installation samples of the PV system integrated with construction materials in each country. In Task 8: Investigative study of possibilities of the large-scale photovoltaic power generation using the unused land such as desert, a report making of the secondary survey was started. (NEDO)

  9. FY 1992 Report on the results of the research and development of manganese nodule collection system. Total system (Test schedules); 1992 nendo mangan dankai saiko system no kenkyu kaihatsu (mangan dankai saiko system) seika hokokusho. 2/5. Total system (jikken keikaku) hen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-03-01

    This project is aimed at development of the fluid dredging type technologies for collecting manganese nodules on deep sea beds (4,000 to 6,000m deep), in order to secure stable supply of the non-ferrous metal resources and improve marine development technologies. The test sea area determined is the seamount JA-4 south of the Minami-Torishima Island. The test schedule preparation working group has drawn the draft test schedules; the phase 1 tests (including water lifting and towing tests) at the TA-GA area, a sea area with a relatively thick acoustic transparent layer, located on the east side of the center of the flat peak of the seamount, and phase 2 tests (including mineral lifting tests) at the TA-GB area, a terrace on the south-east side of the flat peak of the seamount, where seamount manganese nodules are massively occurring. The studies for preparing the test schedules are started, based on the drafts, and also the studies are implemented for the test implementation manuals, including those suitable for No.3 Hakuryu as the test vessel. The other items studied include the basic studies on the air lift system for collecting minerals on a commercial scale, and on economic evaluation. (NEDO)

  10. Basic investigation on promotion of joint implementation in fiscal 2000. Investigations on modification and improvement project for Potoshani district heating and heat supplying facilities in Romania; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Romania koku Potoshani chiiki danbo netsukyokyu setsubi no kaishu oyobi kaizen keikaku chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Discussions have been given on the improvement and modification project intended of saving energies and reducing greenhouse gas emission in the Potoshani district heating and heat supplying facilities in Romania. Thirty years have elapsed since the building of the Potoshani district heating and heat supplying facilities, whereas noticeable energy loss has occurred due to aged deterioration, such as thermal efficiency decrease, performance decrease, and hot water leakage due to piping corrosion. The present project is intended to improve the heat production and power generation facility efficiencies, and reduce the heat loss in heat transportation and distribution to less than 5%. The improvements will be implemented by replacing and rehabilitating the existing boilers, replacing the turbine generators, and replacing the transportation and distribution pipelines and heat exchangers. As a result of the discussions, the present project is estimated to result in annual fuel conservation of 35,820 tons of crude oil equivalent, and annual reduction of the greenhouse gas emission of 110,835 t-CO2. The total amount of the initial investment for the project would be 11.369 billion yen, and the payback period would be 12 years. The project will produce profit of 31.358 billion yen in 20 years, thus the project is financially feasible. (NEDO)

  11. Report on New Sunshine Program-supported undertakings for fiscal 1997. Development of hot water power plant and deep-seated geothermal resources sampling/exploiting technologies; 1997 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu, shinbu chinetsu shigen saishu gijutsu no kaihatsu, shinbu chinetsu shigen seisan gijutsu no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Reported are the results of researches conducted in fiscal 1997. In the field of PTSD (Pressure, Temperature, Spinner flowmeter, fluid Density) well logging, the high-temperature performance of a memory type PT (Pressure, Temperature) well logger is confirmed in a demonstration test. As for the S-probe, modification is effected for the reduction of the outside diameter from 70mm to 56mm, and tests are conducted in real wells. As for the D-probe, a laboratory test is conducted and then the probe behaves as predicted. In the field of PCT (Pressure, Chemical, Temperature) monitoring, the sampler is subjected to an on-site test in Italy, when water is successfully sampled out of the well. In the field of scale monitoring technique, deep-seated fluid is collected and examined, and the scale deposition rate in the deep-seated fluid is determine. For the study of production control technology with respect to scale prevention and removal, an Mg-Si scale synthesis test is conducted in the temperature range of 100-300degC, and it is found that the solubility of scale decreases with a rise in temperature. 19 refs., 93 figs., 24 tabs.

  12. FY 1999 report on the plan to implement the model project for effective utilization of blast furnace gas pressure energy and the potential survey of the spread in India; 1999 nendo Indo ni okeru koro gas atsuryoku energy yuko riyo model jigyo jisshi keikaku oyobi fukyu kanosei chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    As to the implementation of 'the model project for effective utilization of blast furnace gas pressure energy' and the possibility of spreading the said technology, survey/study were conducted, and the results were reported. The enterprise implementing the model project, Steel Authority of India Limited (SAIL), has been investing a total of 300 billion yen in modernizing facility/equipment after the liberalization in 1992, which is a cause of a large amount of deficit. About SAIL' cash flow, it is expected that SAIL will go into the black after tax in and after 2002. Local financial institutions are careful in investing in the iron/steel industry, but they have no problems in their own financing ability. In the evaluation of economical efficiency on the commercial basis, it is difficult to implement this model if using power prices, customs duties and borrowing rates in India as conditions. However, when preferential measures such as the exemption from taxation and help to borrowing rates are taken for energy conservation facility/equipment and the cost reduction is realized by technical cooperation, etc., it will be possible to recover the investment in 5 years. As to the possibility of spreading this model, the blast furnace with a capacity of 1000{sup 3} or more is targeted, and the number of the targeted blast furnace is 23. (NEDO)

  13. Achievement report for fiscal 1998 (edition B) on auxiliary New Sunshine Project. Development of coal hydrogasification technology (Research by using experimental device); 1998 nendo New Sunshine keikaku hojo jigyo seika hokokusho (B ban). Sekitan suiso tenka gaska gijutsu kaihatsu - Jikken sochi ni yoru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    With an objective of using practically the coal hydrogasification technology (the ARCH process), developmental research has been performed on important elementary technologies using different experimental devices. This paper summarizes the achievements in fiscal 1998. In the research by using a small testing apparatus, the Taiheiyo coal was used to have derived hydrogasification data (distribution and yield of the reaction products) in case of having changed the reaction pressure, temperature rising rate, and H{sub 2}/caoal ratio, and to verify the possibility of increasing the BTX yield by installing a temperature zone in two steps. In the developmental research on the injector, a combustion test and a coal feeding test were performed on the injector having been designed and fabricated in the previous fiscal year to verify the basic performance and evaluate the heat resistance and durability. With respect to the hot model test, a test installation was completed with the injector mounted to conduct the trial operation and test. In addition, development was conducted on the coal temperature rise simulation as the second phase of developing the simulation of mixing of coal with high-temperature hydrogen and temperature rise. (NEDO)

  14. Research and development project for large industrial technologies in fiscal 1989. Achievement report on research and development of manganese nodule mining system - Volume 2/6 (Edition for total system - experiment program); 1989 nendo mangan dankai saiko system no kenkyu kaihatsu seika hokokusho. 2/6. Total system (jikken keikaku) hen

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-03-01

    With an objective to ensure non-ferrous metal resources such as nickel, cobalt, copper and manganese, and enhance the ocean development technologies, research and development has been performed on a technology to mine by using the fluid dredge system the manganese nodules existing in ocean bottoms as deep as 4,000 to 6,000 m. This paper summarizes the achievements in fiscal 1989. This fiscal year has reviewed and rationalized the experiment program for the purpose of largely reducing the experimental expense without damaging the purpose and achievement of the experiment. In the rationalized program, such programs were established as the dock side test at the quay and off shore of the Kobe Shipyard, a comprehensive trial operation in the sea area with depth of about 2,000 m, and comprehensive experiments in the sea area around 9 degrees 10 minutes north latitude and 146 degrees 30 minutes west longitude with depth of 5,150 m. Based on these programs, discussions were given on the personnel plan, operation management, fuel, and lubrication oil for the experimental vessel. In addition, discussions were given on the operation, maintenance management, operation management, communications, safety control, and hurricane countermeasures as the experiment implementation procedures. Furthermore, such discussions were given as investigation and selection of the environmental effects and the experimental sea areas for the experiment system. (NEDO)

  15. Report on investigations in fiscal 2000 on the basic investigation on promotion of joint implementation. Project to utilize coal bed methane gas for power generation in Poland; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Poland tanko methane gas hatsuden riyo keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Having the Mining Industry Restructuring Public Corporation located in the city of Katowice, Poland as the counterpart, a feasibility study has been executed on a project to utilize coal bed gas for power generation. Selected for the study are the 'Budryk coal mine' owned by KWK 'Budryk' Coal Company and the 'Pniowek coal mine' owned by Jastrzebie Coal Company. Since the Pniowek coal mine can utilize the whole quantity of recovered methane by 2001, the Budryk coal mine was selected as the object of the project. As a result of the trial calculation on the economy when the new gas power plant is installed in the Budryk coal mine, the energy substitution effect was found to equal to a power amount at transmission terminal of 6 MWh/year. Furthermore, when proliferation effect is taken into consideration, an enormous effect can be expected if new coal mines are developed and the existing cola mines will go further deeper, because the Silesian coal mine presently has the coal resource quantity of 57 billion tons and the annual gas discharge quantity of 750 million m{sup 3}. Therefore, if the technologies to recover, manage and utilize the gas are established at the Budryk coal mine, a large effect leading to an aspiration would be expected under the current situation of the structural reorganization under which the Polish coal companies are placed. (NEDO)

  16. FY 2000 report on the basic survey to promote Joint Implementation, etc. Project on methane gas recovery use in the Donetsk coal field/coal mine; 2000 nendo kyodo jisshi nado suishin kiso chosa hokokusho. Donetsk tanden tanko methane gas kaishu riyo keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of getting petroleum substitution energy and reducing greenhouse effect gas emission, an investigational study was carried out of the project for methane gas recovery/utilization at the Donbassa coal mine in Ukraine. At the Donbassa coal mine, degassing by test boring is being conducted to reduce the gas emission at coal face for safety, but most of the gas is discharged into the air. In this project, the following were studied: degassing boring/gas induction from bore hole/measurement in gas induction pipe, gas recovery system combined with gas induction in flyash, and installation/operation of gas engine power generation facilities (1,710kW x 7 units) with exhaust heat recovery boiler using the recovered methane gas as fuel. The results obtained were the petroleum substitution amount of 31,000 toe/y and the amount of greenhouse effect gas reduction of 480,000 t/y. In the economical estimation, the initial investment amount was 3 billion yen, the profitability of the total investment used was 2.9%, and the internal earning rate was 6.5%. (NEDO)

  17. Fiscal 1997 report on the results of the introductory R and D of the New Sunshine Project under a consignment from NEDO. Introductory R and D of the supercritical fluid use technology; 1997 nendo `New Sunshine keikaku` sendo kenkyu kaihatsu Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Chorinkai ryutai riyo gijutsu sendo kenkyu kaihatsu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The R and D of chemical reaction using supercritical fluids started in fiscal 1997. In the R and D of solvent reaction, as the research on polymer decomposition with supercritical water, studies were conducted of the mechanism of conversion reaction to chemical materials, cleavage mechanism of stable chemical bonds, and synthetic reaction in the supercritical state reaction field. In the research on oxidation reaction, as the study of complete oxidation in supercritical water for high efficiency energy recovery, studies of complete oxidation of liquid fuels, and complete oxidation of solid fuels. In the research on hydrogenation, studies of lightening of heavy oil in supercritical water, etc. In the R and D of the basic technology, studies of corrosion mechanism of metals in supercritical water, construction of the basic framework for technical database of supercritical fluids, etc. In the survey of technical trends and new research themes, the introductory R and D of element technology, etc. were conducted, and the results were described of the survey of technical trends and new research themes and the trend survey of overseas technology. 314 refs., 87 figs., 81 tabs.

  18. Feasibility study on plan to utilize livestock excreta for bio-gas in Miyagi Village (Gunma Prefecture). Investigations on projects including district new energy vision establishment in fiscal 2000, and on feasibility for commercialization; Miyagimura chikusan haisetsubutsu bio gas ka energy riyo keikaku feasibility study. 2000 nendo chiiki shin energy vision sakutei nado jigyo, jigyoka feasibility study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-02-01

    With objectives to utilize energy available from livestock excreta, and to properly treat the livestock excreta, a feasibility study was performed on a plan to utilize livestock excreta for bio-gas. The system to be developed is a livestock wastes treatment system to utilize gas generated by efficiently fermenting the excreta as fuel, and residual sludge solids as compost. The activity achievements were put into order by the following nine items: 1) purpose of the feasibility study, 2) method for the feasibility study, 3) the situation where the livestock industry and the hog raising industry were selected as the object of the investigation, 4) properties of hog excreta, characteristics in urine foul water treatment, technologies for urine foul water treatment (biological treatment), 5) bio-gasification of livestock wastes, 6) the basic conditions for investigating the demonstration bio-bas plants, 7) proposals and standard cases of the demonstration bio gas plants, 8) discussions and positioning of the basic system for the demonstration bio gas plants, and 9) conclusion. (NEDO)

  19. Fiscal 1993 report on results of R and D on manganese nodule mining system. Manganese nodule mining system (Total system - experiment plan part); 1993 nendo mangan danakai saiko system no kenkyu kaihatsu seika hokokusho. 2/5. Mangan dankai saiko system (total system (jikken keikaku) hen)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    Technology is being developed for mining the nodules existing at a depth of 4,000-6,000 m by a fluid dredge method, with the purpose of securing steady supply of non-ferrous metal resources and enhancing oceanic development technologies. To be concrete, comprehensive oceanic experiments will be conducted in the GA-04 sea area, 600 km southeast of Marcus Island, by developing and experimentally preparing a test system for the mining. In the R and D of a total system, activities were carried out in the two areas of (1) experimental operation section for design and manufacture of experimental equipment and comprehensive experimental simulation, and (2) experimental planning operation section for experimental policy, survey and analysis of sea area for experiment, and research on mining system. In (2), examination of the experiment implementation plan was carried out in the case where, as the experimental plan, the first stage experiment is implemented in TA-GA sea area and the second stage experiment in TA-TB sea area with abundant nodules of a submarine mountain in the area; examination was also made on the draft of an experiment implementation guideline suitable for M.S. Hakuryu No.3 as the experimental boat as well as on various guideline plans. In addition, a sensitivity analysis was made on the mining system as the evaluation of cost effectiveness in the case of commercial production. (NEDO)

  20. FY 1993 report on the results of the subsidy project for the Sunshine Project. Development of coal use hydrogen production technology (Support study of pilot plant - Study using the small equipment); 1993 nendo Sunshine keikaku hojo jigyo seika hokokusho. Sekitan riyo suiso seizo gijutsu kaihatsu - Pilot plant no shien kenkyu (Kogata souchi ni yoru kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    As to the development of coal use hydrogen production technology, the paper studied the reactivity of char and ignition characteristics of various coals in the use of electric furnace and the participation in pilot plant test and the improvement, and the FY 1993 results were reported. In the study of reactivity of char, it was found that the reactivity was the same, regardless of the equipment and kind of raw coal, if considered of the ratio of the total oxygen amount (the char-containing oxygen amount added to the oxygen supply amount) to the carbon supply amount in char. In the test on ignition characteristics of overseas coals, the same characteristics as those of the Taiheiyo coal conventionally tested were obtained and it was found that it was good to use the same method for start-up of gasifier as conventionally used. In the pilot plant test in the previous year, slag and ash stuck to the outlet of the gasification part and heat recovery part and developed, which hindered the continued operation. To improve it, the following were carried out: model study, study of ash sintering, study using the synthetic test equipment, analysis of the deposit in gasifier, etc. Based on these results, the plant was improved, and the continued operation of 1,149 hours was stably achieved in RUN8. (NEDO)

  1. Reports on 1977 result of research. Investigation for selecting site location of pilot plant for 7,000Nm{sup 3}/day class high calorie gasification; 1977 nendo sunshine keikaku ni kakawaru plant kenkyu kaihatsu seika hokoku. 7,000Nm{sup 3}/nichi kyu kokarori gas ka pilot plant yochi no ricchi sentei chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1978-03-20

    A report was made on the result of investigation for selecting a suitable site for a coal gasification pilot plant. The high calorie gasification plant under the Sunshine Project is scheduled to have a parallel operation of two methods. It could be decided on one only method depending on the future studies. One is the 'water gasification method' using coal only as the raw material, with hydrogen gas added to contrive methanization. The other is the 'hybrid gasification method' using mixed slurry of powdered coal and heavy oil as the raw material, with oxygen supplied to it to form a clean gas. The sites proposed for the pilot plant are the cities of Yubari, Iwaki, Kita-Ibaraki, Tagawa, Iizuka and Imari. The items for assessment of cost effectiveness are the expenses of development of a site, road construction, removal of existing obstacles, plant construction, power receiving equipment construction, irrigation supply facilities construction, wastewater treatment system construction, ash discharging system construction, transportation, and supply/processing-related maintenance. As a result of the assessment, Iwaki city was picked up as the area almost free from drawbacks to cost effectiveness. (NEDO)

  2. Fiscal 1999 research report. Support project for formation of the energy and environment technology demonstration project (International joint demonstration research). Underground coal gasification and cogeneration power plant construction plan; 1999 nendo sekitan chika gas ka oyobi netsuden heikyu plant kensetsu keikaku seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This research was made as the joint demonstration research project with National Mining University of Ukraine having abundant scientific information on underground coal gasification (UCG) technology. The research themes are as follows: (1) Verification of UCG element technologies, (2) Verification and proposal on combined cycle power generation, (3) Profitability of UCG, and (4) Future trend of UCG. The result of (1) on linking, ignition and UCG reaction process control technologies showed that the level of Ukraine is equivalent to that of leading western countries. Thermal behavior simulation on ground water, and experiment on mass transfer considering environment impact were also made. The result of (2) showed low calorific value of UCG gas, difficulty in use as chemical raw material or power generation fuel, and applicability to only small-scale cogeneration systems. The result of (3) showed the profitability of UCG gas higher than that of general coals. The result of (4) showed that in spite of various problems, UCG is very practical and promising as near future coal use technology. (NEDO)

  3. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Research and development of solar cell evaluation system - Survey of research and development of solar cell evaluation system); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyodenchi hyoka system no kenkyu kaihatsu - Taiyodenchi hyoka system no kenkyu kaihatsu chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Surveys and studies were conducted for establishing methods for evaluating solar cell performance and reliability. In the effort to develop basic technologies for the comprehensive evaluation of the performance of various types of solar cells and modules, an ultrahigh matching solar simulator and a large area solar simulator were built. The long-term exposure tests of solar cell modules kept on at 5 sites in Japan, 3 sites in Australia, and 1 site in Oman, and the databasing of the test data was planned. In the long-term evaluation of solar cell durability, investigations centered about module deterioration, where abnormal heat generation was observed, cause of increased resistance was inspected, and separation between the cell and the filler was examined. In the development of an accelerated photodegradation test method, it was found that the result of a light-dark cycle test with the ambient temperature varied agreed excellently with the results of outdoor exposure tests. It was consequently proved that the light-dark cycle test was a very promising candidate for an accelerated photodegradation test for a-Si solar cells. (NEDO)

  4. Research report for fiscal 1998. Basic research for promoting joint implementation, etc. (fuel change plan for No. 1 and No. 9 Irkutsk Heat and Power Co-Generation Plants, Irkutsk, Russia); 1998 nendo chosa hokokusho. Roshia renpo Irkuktsk shu dai 1 go oyobi dai 9 go Irkutsk netsu heikyu hatsudensho nenryo tenkan keikaku

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A research is conducted to find out if efficiency will increase and greenhouse gas will decrease when fuel is changed from coal to gas at the above-named plants, and the economics of the plan is reviewed. The No. 1 plant comprises 18 coal-fired boilers with a total design capacity of 2985 tons/hour, and 8 steam turbine generators rated at 185MW, constructed in the 1940s. The No. 9 plant was constructed in the 1960s and 1970s. Four different modifications programs are drafted to study the fuel change plan. As the result, it is found that the addition of natural gas burning facilities to the existing heat and power co-generation plants and the modification of the existing boiler-related facilities will be low in earning rate and reliability, though excellent in budget size and cost efficiency; and that to dismantle the existing plants and to newly construct heat and power plants operating on gas turbines will bring about a higher earning rate, fuel cost reduction effect, and reliability, though such will cost more. (NEDO)

  5. Fiscal 1997 project on the R and D of industrial scientific technology under consignment from NEDO (book on the handling / gas lift system). Report on the results of the R and D of the overall base technology of ocean resources (R and D of submarine oil drilling technology, etc.); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shine Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Kaiyo shigen sogo kiban gijutsu no kenkyu kaihatsu (kaitei sekiyu kussaku gijutsu nado kenkyu kaihatsu) seika hokokusho (handling / gas lift system hen)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    The paper conducted a R and D on the handling of drilling equipment in drilling/collecting of submarine oil and the gas lift of artificial oil extraction technology. As to each equipment of a barge style handling system, conducted were assembly/adjustment/trial run on land and pipe handling experiments on sea. In the experiment, confirmed were pipe transfer function, lifting function, fitting function, grasping function, etc. In the ocean experiment, studied were pipe bending stress, Karman vortex control effects, etc. Relating to the gas lift system, experiments were made on confirmation of fabrication/performance of air compressor. Moreover, a technique of air transportation to the blowing inlet of the gas lift pipe was established by developing an air blowing system and fabricating a long-distance flexible pipe. Concerning the gas/liquid/solid three-phase separator, a cyclone separator was developed, and improvement in lifting efficiency was confirmed. Helped by these, the problems of the gas lift system were almost solved, and a possibility of the commercial-base production system was obtained. 2 refs., 182 figs., 47 tabs.

  6. Resveratrol and Endothelial Nitric Oxide

    Directory of Open Access Journals (Sweden)

    Ning Xia

    2014-10-01

    Full Text Available Nitric oxide (NO derived from the endothelial NO synthase (eNOS has antihypertensive, antithrombotic, anti-atherosclerotic and antiobesogenic properties. Resveratrol is a polyphenol phytoalexin with multiple cardiovascular and metabolic effects. Part of the beneficial effects of resveratrol are mediated by eNOS. Resveratrol stimulates NO production from eNOS by a number of mechanisms, including upregulation of eNOS expression, stimulation of eNOS enzymatic activity and reversal of eNOS uncoupling. In addition, by reducing oxidative stress, resveratrol prevents oxidative NO inactivation by superoxide thereby enhancing NO bioavailability. Molecular pathways underlying these effects of resveratrol involve SIRT1, AMPK, Nrf2 and estrogen receptors.

  7. On the application of subcell resolution to conservation laws with stiff source terms

    International Nuclear Information System (INIS)

    Chang, S.

    1989-11-01

    LeVeque and Yee recently investigated a one-dimensional scalar conservation law with stiff source terms modeling the reacting flow problems and discovered that for the very stiff case most of the current finite difference methods developed for non-reacting flows would produce wrong solutions when there is a propagating discontinuity. A numerical scheme, essentially nonoscillatory/subcell resolution - characteristic direction (ENO/SRCD), is proposed for solving conservation laws with stiff source terms. This scheme is a modification of Harten's ENO scheme with subcell resolution, ENO/SR. The locations of the discontinuities and the characteristic directions are essential in the design. Strang's time-splitting method is used and time evolutions are done by advancing along the characteristics. Numerical experiment using this scheme shows excellent results on the model problem of LeVeque and Yee. Comparisons of the results of ENO, ENO/SR, and ENO/SRCD are also presented

  8. Exhaled Nitric Oxide is Decreased by Exposure to the Hyperbaric Oxygen Therapy Environment

    Directory of Open Access Journals (Sweden)

    Zudin A. Puthucheary

    2006-01-01

    or 40% oxygen, 1 ATA. In an in vitro study, nitrate/nitrite release decreased after 90 minutes HBOT in airway epithelial (A549 cells. Conclusion. HBO exposure causes a fall in eNO. Inducible nitric oxide synthase (iNOS may cause elevated eNO in patients secondary to inflammation, and inhibition of iNOS may be the mechanism of the reduction of eNO seen with HBOT.

  9. Exhaled Nitric Oxide Is Useful in Symptomatic Radioactive Pneumonia: A Retrospective Study

    Directory of Open Access Journals (Sweden)

    Jiancheng Li

    2017-01-01

    Full Text Available The aim was to defect the exhaled nitric oxide (eNO prediction value of symptomatic radioactive pneumonia (SRP. 64 cases of lung cancer or esophagus cancer, who had the primary radiotherapy (intensity-modulated radiation therapy, were included from 2015 June to 2016 January. During the following, the patients were divided: the symptomatic radiation pneumonia group (SRP, with the CTCAE v4.0 score > 2 and the asymptomatic radiation pneumonia group (ASRP, with CTCAE v4.0 score ≤ 1. All the patients were measured eNO before and at the end of thoracic radiotherapy and gain the posttherapy eNO value and the eNO ratio (posttherapy eNO value/pretherapy eNO value, then the predictive values of eNO toward SRP were measured using the receiver-operating characteristic (ROC. 17 cases were included in the SRP group and the other 47 were included in the ASRP group. The posttherapy eNO was 29.35 (19~60 bbp versus 20.646 (11~37 (P<0.001, and the ratio was 1.669 (0.61~3.5 versus 0.920 (0.35~1.5 (P<0.01 (symptomatic versus asymptomatic. ROC showed that the cutoff value of SRP was 19.5 bbp (posttherapy eNO, area under concentration-time curve (AUC = 0.879 and 1.305 (eNO ratio, AUC = 0.774, which meant that posttherapy eNO and eNO ratio were useful in finding SRP.

  10. Association of endothelial nitric oxide synthase gene polymorphism with the risk of Henoch-Schönlein purpura/Henoch-Schönlein purpura nephritis.

    Science.gov (United States)

    Zhong, Weiqiang; Zhou, Tian-Biao; Jiang, Zongpei

    2015-04-01

    Association between endothelial nitric oxide synthase (eNOS) gene polymorphism and Henoch-Schönlein purpura (HSP)/Henoch-Schönlein purpura nephritis (HSPN) risk is still controversial. A meta-analysis was performed to evaluate the association between eNOS gene polymorphism and HSP/HSPN susceptibility. A predefined literature search and selection of eligible relevant studies were performed to collect data from electronic database. Three articles were identified for the analysis of association between eNOS gene polymorphism and HSPN/HSP risk. eNOS G894T gene polymorphism was not associated with HSPN susceptibility and the risk of patients with HSP developing into HSPN. Interestingly, eNOS G894T T allele and GG genotype were associated with HSP susceptibility, but not the TT genotype. eNOS T786C TT genotype was associated with HSPN susceptibility, but not C allele and CC genotype. Furthermore, eNOS T786C gene polymorphism was not associated with HSP risk and the risk of patients with HSP developing into HSPN. In conclusion, eNOS T786C TT genotype was associated with and eNOS G894T T allele and GG genotype were associated with HSP susceptibility. However, more studies should be performed in the future.

  11. Posttranslational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis

    Science.gov (United States)

    Musicki, Biljana; Champion, Hunter C.; Hsu, Lewis L.; Bivalacqua, Trinity J.; Burnett, Arthur L.

    2017-01-01

    INTRODUCTION Sickle cell disease (SCD)-associated priapism is characterized by endothelial nitric oxide synthase (eNOS) dysfunction in the penis. However, the mechanism of decreased eNOS function/activation in the penis in association with SCD is not known. AIMS Our hypothesis in the present study was that eNOS is functionally inactivated in the SCD penis in association with impairments in eNOS posttranslational phosphorylation and the enzyme’s interactions with its regulatory proteins. METHODS Sickle cell transgenic (sickle) mice were used as an animal model of SCD. Wild type (WT) mice served as controls. Penes were excised at baseline for molecular studies. eNOS phosphorylation on Ser-1177 (positive regulatory site) and Thr-495 (negative regulatory site), total eNOS, and phosphorylated AKT (upstream mediator of eNOS phosphorylation on Ser-1177) expressions, and eNOS interactions with heat shock protein 90 (HSP90) and caveolin-1 were measured by Western blot. Constitutive NOS catalytic activity was measured by conversion of L-[14C]arginine-to-L-[14C]citrulline in the presence of calcium. MAIN OUTCOME MEASURES Molecular mechanisms of eNOS dysfunction in the sickle mouse penis. RESULTS eNOS phosphorylated on Ser-1177, an active portion of eNOS, was decreased in the sickle mouse penis compared to WT penis. eNOS interaction with its positive protein regulator HSP90, but not with its negative protein regulator caveolin-1, and phosphorylated AKT expression, as well as constitutive NOS activity, were also decreased in the sickle mouse penis compared to WT penis. eNOS phosphorylated on Thr-495, total eNOS, HSP90, and caveolin-1 protein expressions in the penis were not affected by SCD. CONCLUSION These findings provide a molecular basis for chronically reduced eNOS function in the penis by SCD, which involves decreased eNOS phosphorylation on Ser-1177 and decreased eNOS-HSP90 interaction. PMID:21143412

  12. Requirement of phosphorylatable endothelial nitric oxide synthase at Ser-1177 for vasoinhibin-mediated inhibition of endothelial cell migration and proliferation in vitro.

    Science.gov (United States)

    García, Celina; Nuñez-Anita, Rosa Elvira; Thebault, Stéphanie; Arredondo Zamarripa, David; Jeziorsky, Michael C; Martínez de la Escalera, Gonzalo; Clapp, Carmen

    2014-03-01

    Endothelial nitric oxide synthase (eNOS)-derived nitric oxide is a major vasorelaxing factor and a mediator of vasopermeability and angiogenesis. Vasoinhibins, a family of antiangiogenic prolactin fragments that include 16 K prolactin, block most eNOS-mediated vascular effects. Vasoinhibins activate protein phosphatase 2A, causing eNOS inactivation through dephosphorylation of eNOS at serine residue 1179 in bovine endothelial cells and thereby blocking vascular permeability. In this study, we examined whether human eNOS phosphorylation at S1177 (analogous to bovine S1179) influences other actions of vasoinhibins. Bovine umbilical vein endothelial cells were stably transfected with human wild-type eNOS (WT) or with phospho-mimetic (S1177D) or non-phosphorylatable (S1177A) eNOS mutants. Vasoinhibins inhibited the increases in eNOS activity, migration, and proliferation following the overexpression of WT eNOS but did not affect these responses in cells expressing S1177D and S1177A eNOS mutants. We conclude that eNOS inhibition by dephosphorylation of S1177 is fundamental for the inhibition of endothelial cell migration and proliferation by vasoinhibins.

  13. Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells.

    Science.gov (United States)

    Ugusman, Azizah; Zakaria, Zaiton; Hui, Chua Kien; Nordin, Nor Anita Megat Mohd

    2010-07-01

    Nitric oxide produced by endothelial nitric oxide synthase (eNOS) possesses multiple anti-atherosclerotic properties. Hence, enhanced expression of eNOS and increased Nitric oxide levels may protect against the development of atherosclerosis. Piper sarmentosum is a tropical plant with antioxidant and anti-inflammatory activities. This study aimed to investigate the effects of Piper sarmentosum on the eNOS and Nitric oxide pathway in cultured human umbilical vein endothelial cells (HUVECs). HUVECS WERE DIVIDED INTO FOUR GROUPS: control, treatment with 180 microM hydrogen peroxide (H(2)O(2)), treatment with 150 microg/mL aqueous extract of Piper sarmentosum, and concomitant treatment with aqueous extract of PS and H(2)O(2) for 24 hours. Subsequently, HUVECs were harvested and eNOS mRNA expression was determined using qPCR. The eNOS protein level was measured using ELISA, and the eNOS activity and Nitric oxide level were determined by the Griess reaction. Human umbilical vein endothelial cells treated with aqueous extract of Piper sarmentosum showed a marked induction of Nitric oxide. Treatment with PS also resulted in increased eNOS mRNA expression, eNOS protein level and eNOS activity in HUVECs. Aqueous extract of Piper sarmentosum may improve endothelial function by promoting NO production in HUVECs.

  14. Piper sarmentosum increases nitric oxide production in oxidative stress: a study on human umbilical vein endothelial cells

    Directory of Open Access Journals (Sweden)

    Azizah Ugusman

    2010-01-01

    Full Text Available OBJECTIVE: Nitric oxide produced by endothelial nitric oxide synthase (eNOS possesses multiple anti-atherosclerotic properties. Hence, enhanced expression of eNOS and increased Nitric oxide levels may protect against the development of atherosclerosis. Piper sarmentosum is a tropical plant with antioxidant and anti-inflammatory activities. This study aimed to investigate the effects of Piper sarmentosum on the eNOS and Nitric oxide pathway in cultured human umbilical vein endothelial cells (HUVECs. METHODS: HUVECs were divided into four groups: control, treatment with 180 μM hydrogen peroxide (H2O2, treatment with 150 μg/mL aqueous extract of Piper sarmentosum, and concomitant treatment with aqueous extract of PS and H2O2 for 24 hours. Subsequently, HUVECs were harvested and eNOS mRNA expression was determined using qPCR. The eNOS protein level was measured using ELISA, and the eNOS activity and Nitric oxide level were determined by the Griess reaction. RESULTS: Human umbilical vein endothelial cells treated with aqueous extract of Piper sarmentosum showed a marked induction of Nitric oxide. Treatment with PS also resulted in increased eNOS mRNA expression, eNOS protein level and eNOS activity in HUVECs. CONCLUSION: Aqueous extract of Piper sarmentosum may improve endothelial function by promoting NO production in HUVECs.

  15. Six Open Questions about the Migration of Engineered Nano-Objects from Polymer-Based Food Contact Materials: A Review

    DEFF Research Database (Denmark)

    Jokar, Maryam; Pedersen, Gitte Alsing; Löschner, Katrin

    2017-01-01

    . Current research focusing on FCMs has often reached inconsistency regarding migration of ENOs. The scope of this critical review is to give a concise overview of the most relevant aspects of the subject, and to identify and discuss the major open questions in relation to migration of ENOs from FCMs....... This includes the very fundamental questions whether ENOs can migrate from FCMs at all and what the potential release mechanisms of ENOs could be. The inconsistency of findings from experimental studies is highlighted based on the example of silver nanoparticle migration from polymer-based FCMs. Challenges...

  16. Crystal structure of enolase from Drosophila melanogaster.

    Science.gov (United States)

    Sun, Congcong; Xu, Baokui; Liu, Xueyan; Zhang, Zhen; Su, Zhongliang

    2017-04-01

    Enolase is an important enzyme in glycolysis and various biological processes. Its dysfunction is closely associated with diseases. Here, the enolase from Drosophila melanogaster (DmENO) was purified and crystallized. A crystal of DmENO diffracted to 2.0 Å resolution and belonged to space group R32. The structure was solved by molecular replacement. Like most enolases, DmENO forms a homodimer with conserved residues in the dimer interface. DmENO possesses an open conformation in this structure and contains conserved elements for catalytic activity. This work provides a structural basis for further functional and evolutionary studies of enolase.

  17. FY 1994 report on the results of the project supplementary to the New Sunshine Project - Development of the coal utilization hydrogen production technology. Ninth year - Part 2. Study using a pilot plant (Design/construction/operation study of the pilot plant and the dismantling study); 1994 nendo New Sunshine keikaku hojo jigyo Dai 9 nenji bun seika hokokusho - 2. Sekitan riyo suiso seizo gijutsu kaihatsu - Pilot plant ni yoru kenkyu (Pilot plant no sekkei kensetsu unten kenkyu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-03-01

    In the R and D of the high temperature coal gasification technology by the entrained bed system which is the core technology of the coal utilization hydrogen production technology, the paper carried out the dismantling study of pilot plant and the summarization of the results. About the summarization of the results, as the results of the HYCOL operation study, there were insufficiencies in expansion of the coal kind used and acquisition of scale-up data, but it was verified that the conceptual design of the HYCOL method was fully applicable to the higher gasification efficiency, higher reliability, adaptability to many kinds of coal and compactness of facilities (low construction cost) which were the final subjects for the realization of commercial plant. This was highly evaluated. Especially, the greatest characteristic of the HYCOL method is the freedom in selection of temperature difference between the upper stage and lower stage, that is, temperatures can be controlled to temperatures they want in each of the upper stage and lower stage in the one-chamber gasifier according to coal properties and slagging control. The verification of this freedom was the base of the total results. Moreover, a reputation was being made that the gasification efficiency and process reliability are at the world's highest level. (NEDO)

  18. FY 2000 report on the results of the development of technology for commercialization of the photovoltaic power system - R and D of evaluation technology of the photovoltaic power system. Separate volume. R and D of the system evaluation technology (Data book on the photovoltaic power system); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Taiyoko hatsuden system hyoka gijutsu no kenkyu kaihatsu - System hyoka gijutsu no kenkyu kaihatsu (Bessatsu : Taiyoko hatsuden system data shu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of establishing the optimum design and optimum operation technology of various kinds of photovoltaic power system, data were collected to make a data book on various kinds of photovoltaic power system of which the future commercialization is expected. Included in this data book were the monthly report on operation data on demonstrative test facilities at the Hamamatsu site of JQA (Japan Quality Assurance Organization), daily graph of insolation/temperature, monthly graph of wind direction/wind velocity. Further, as the data on the residential use photovoltaic power system, data on the following were summed up: information on the site of installation of the residential use photovoltaic power system (photo information, the state of installation such as sites installed more in FY 2000, drawings of module arrangement and measuring point layout, etc.), daily report on operation (graph of daily trends, daily report by site, hourly report by site, daily report on all sites, hourly report on all sites), operation data and performance indices, list of troubles arising in the residential use photovoltaic power system, other system information about residential use measuring data, power generation characteristics and {alpha}{sub pmax} of residential use solar cell modules, etc. (NEDO)

  19. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Surveys and studies of peripheral key technologies/Surveys of environmentally-friendliness enhancement for next-generation solar cell development); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu (Shuhen yoso gijutsu ni kansuru kenkyu chosa, Jisedai taiyodenchi kaihatsu kankyo tekioka chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Though the trends of solar cell development are becoming increasingly diverse across the world, yet none has emerged to promise a stable solar cell supply in the future. Under the circumstances, studies were conducted to clarify strategies for solar cell technology development which would be well adapted to Japan's social environments, with the trends of development in the United States and European countries taken into consideration. The surveys covered the research and development and diffusion of photovoltaic power generation in the United States and European countries, and their solar cell research and development strategies and trends of development were put together. Surveys were also conducted into the research and development of unconventional types of solar cells, such as the dye-sensitized solar cell, organic solar cell, conjugate polymer solar cell, and the polymer/C{sub 60} based solar cell, and into the status of resources of materials for solar cells such as gallium, arsenic, cadmium, tellurium, indium, selenium, and germanium. Regarding the future of photovoltaic power generation research and development, it was concluded that commercialization technology development and basic research and development should continue. Also pointed out was the importance of the enlargement of the market for photovoltaic power generation systems. (NEDO)

  20. New Sunshine Program for fiscal 2000. Development of photovoltaic system commercialization technology - Development of thin-film solar cell manufacturing technology - Development of low-cost/large area module manufacturing technology (Development of novel amorphous solar cell module manufacturing technology); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu, Hakumaku taiyodenchi no seizo gijutsu kaihatsu, Tei cost dai menseki mojuru seizo gijutsu kaihatsu (Shingata amorufasu taiyo denchi mojuru no seizo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Research and development was conducted for the development of amorphous solar cell modules for power generation, high in performance and low in production cost. In the effort to develop high-performance solar cells, optimum device designs including an advanced light confinement structure or the like were studied, and a 25% reduction in the total power generation layer thickness and a 7% increase in efficiency in power generation were consistently achieved in an a-Si/a-SiGe solar cell. In the effort to develop low-cost process technologies, as the result of studies involving the optimization of high-speed film fabrication requirements such as hydrogen dilution and a high-speed/high-precision patterning method and the like, an initial conversion efficiency of 11.2% was attained, which was the world high for a 90 cm times 90 cm-large a-Si/a-SiGe solar cell. This being equivalent to a post-stabilization efficiency of 10%, the fiscal 2000 target was achieved. A solar cell module production cost assessment was performed based on the result, and a module cost of 133 yen/W (in case of 100 MW/year production) was realized, which again meant the achievement of the fiscal 2000 target. (NEDO)

  1. Fiscal 1997 report on the results of the New Sunshine Project subsidiary operation. Development of the geothermal water use power plant, etc. (development of the binary cycle power plant / development of the geothermal well MWD system); 1997 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (binary cycle hatsuden plant no kaihatsu (chinetsusei kussakuji kotei joho kenchi system no kaihatsu))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    For the purpose of improving efficiency and accuracy in geothermal well drilling, the development was conducted of an MWD (measuring while drilling) which detects borehole information in real time. In fiscal 1997, the following R and D were carried out. As to the downhole equipment, the actual well experiment on the sonde was conducted to confirm the basic performance. The design improvement, trial fabrication and experiment were conducted on mud pulse generating valve driving control equipment, bore hole signal processing unit and temperature correction circuit portion in the sonde. Concerning electronic parts, a heat resistance confirming test was conducted for data collection/assessment. Further, jigs were fabricated for tests to confirm working of each equipment. Relating to the ground equipment, conducted were improvement of the decoded program and betterment of the analytical system and interface. As to the development of the analytical system, data on depth were added to the azimuth/inclination obtained from MWD, which enabled indication of a well drilling tracing chart while drilling. 92 figs., 43 tabs.

  2. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Surveys and studies of peripheral key technologies/Surveys of environmentally-friendliness enhancement for next-generation solar cell development); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu (Shuhen yoso gijutsu ni kansuru kenkyu chosa, Jisedai taiyodenchi kaihatsu kankyo tekioka chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Though the trends of solar cell development are becoming increasingly diverse across the world, yet none has emerged to promise a stable solar cell supply in the future. Under the circumstances, studies were conducted to clarify strategies for solar cell technology development which would be well adapted to Japan's social environments, with the trends of development in the United States and European countries taken into consideration. The surveys covered the research and development and diffusion of photovoltaic power generation in the United States and European countries, and their solar cell research and development strategies and trends of development were put together. Surveys were also conducted into the research and development of unconventional types of solar cells, such as the dye-sensitized solar cell, organic solar cell, conjugate polymer solar cell, and the polymer/C{sub 60} based solar cell, and into the status of resources of materials for solar cells such as gallium, arsenic, cadmium, tellurium, indium, selenium, and germanium. Regarding the future of photovoltaic power generation research and development, it was concluded that commercialization technology development and basic research and development should continue. Also pointed out was the importance of the enlargement of the market for photovoltaic power generation systems. (NEDO)

  3. New Sunshine Program for fiscal 2000. Development of photovoltaic system commercialization technology - Development of thin-film solar cell manufacturing technology - Development of low-cost/large area module manufacturing technology (Development of high-reliability CdTe solar cell module manufacturing technology); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu, Hakumaku taiyodenchi no seizo gijutsu kaihatsu, Tei cost dai menseki mojuru seizo gijutsu kaihatsu (Koshinraisei CdTe taiyo denchi mojuru no seizo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Research and development was conducted for reliable CdTe solar cell modules, large in area and high in efficiency. In the study of large-area CdS thin film fabrication, a conversion efficiency of 12.5-14.2% was achieved in a cell in a large-area substrate using a mist method-aided process of continuous CdS film fabrication. In the study of large-area CdTe thin film fabrication, the optimization was studied of the base-forming CdS film fabrication conditions and of the CdTe film fabrication conditions in a method using a CdTe powder processed by dry kneading, and a conversion efficiency peak was found to exist when the CdS film thickness was in the range of 700-900 angstrom. In the fabrication of large-area submodules, a large-area substrate was taken up, and TCO (transparent conducting oxide) film was fabricated by the mist method, CdTe film by the normal pressure CSS method, electrodes by the screen printing method, and CdTe film patterns by the blast method. As the result, a conversion efficiency of 11.0% was achieved. In a cost estimation for large-area CdTe solar cell modules, 140 yen/Wp (conversion efficiency: 11.0%, annual production: 100 MW) was obtained. (NEDO)

  4. New Sunshine Program for fiscal 2000. Development of photovoltaic system commercialization technology - Development of thin-film solar cell manufacturing technology - Development of low-cost/large area module manufacturing technology (Development of novel amorphous solar cell module manufacturing technology); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu, Hakumaku taiyodenchi no seizo gijutsu kaihatsu, Tei cost dai menseki mojuru seizo gijutsu kaihatsu (Shingata amorufasu taiyo denchi mojuru no seizo gijutsu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Research and development was conducted for the development of amorphous solar cell modules for power generation, high in performance and low in production cost. In the effort to improve cell efficiency, experiments were conducted for enhancing bottom a-SiGe cell efficiency for the embodiment of an enhanced-efficiency multi-junction cell, for improving crystallinity in microcrystalline silicon through the application of VHF (very high frequency) plasma CVD (chemical vapor deposition), for texturizing metal electrodes on a film substrate, and so forth. In the effort to increase the film fabrication rate, a VHF plasma CVD device was used for studying the effect of the discharge frequency on film deposition and quality, Vpp between the electrodes, and so forth. Studies about the high-throughput production technology centered on the film substrate solar cell process technology and the designing of an optimum geometrical pattern for SCAF (series-connection through apertures formed on film) cells. Production cost was estimated for the SCAF structure film substrate solar cell manufacturing process, and a production cost of 147.1 yen/W (in case of 100 MW/year production) was obtained as achievable under the currently available conditions. (NEDO)

  5. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Surveys and studies of peripheral key technologies/Feasibility study of wet-type solar cell commercialization); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu, Shuhen yoso gijutsu ni kansuru chosa kenkyu - Shissiki taiyo denchi jitsuyoka kanosei chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Dye-sensitized solar cell commercialization was studied for feasibility. Studies were made about photoelectric conversion efficiency and various factors supposedly to affect the life and other properties, and a wet-type (dye-sensitized type) solar cell was fabricated. In an endurance test, the dye-sensitized solar cell retained its initial performance after 3,500 hours of continuous irradiation. A 16 cm{sup 2}-large integrated type Graetzel cell was fabricated, and it achieved a photoelectric conversion efficiency of 4.6%. Furthermore, in the study of Graetzel cells, possibility of the creation of new electrolytic solutions was discussed, a non-TiO{sub 2} dye-sensitized solar cell was fabricated based on the self-assembled electrodeposition of the ZnO dye, and the feasibility was deliberated of a dye-sensitized solar sell using a composite oxide semiconductor. Concerning their development in the future, it was concluded that dye-sensitized solar cells including the Graetzel cell were equipped with the basic characteristics of a next-generation solar cell that would be requested to be low in cost and high in performance. (NEDO)

  6. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Surveys and studies of peripheral key technologies/Surveys of ultrahigh-efficiency solar cell application fields); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu, Shuhen yoso gijutsu ni kansuru chosa kenkyu (Chokokoritsu taiyo denchi tou oyo bunya kaitaku chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Surveys and studies were conducted in order to make propositions concerning the fields of application wherein the merits of ultrahigh-efficiency solar cells would be fully utilized. A questionnaire was held about solar cell application fields, and studies were made about new systems based on the need in the market for specific solar cell goods and capable of supporting their mass diffusion. Proposed as the result was the establishment of a rental (lease) system for photovoltaic power systems, a local photovoltaics advisory system, a market for used photovoltaic power systems, and so forth. In the feasibility study of photovoltaic power generation on unused land in agricultural villages, surveys were conducted concerning energy problems, the energy structure, the actual state of energy consumption, the abandoned farm and its utilization, and so forth. Propositions involving photovoltaic power feasibility were then made, which covered power consumption for greenhouse culture, energy supply for producing methanol out of biomass, power sources for insect incapacitating yellow fluorescent lamps, power sources for livestock barn air-conditioning, power sources for animal excretion treatment, and so forth. (NEDO)

  7. Fiscal 1996 report on the results of the subsidy operation under the Sunshine Project on the development of a geothermal water use power plant, etc. Development of the deep geothermal resource collecting technology (development of the deep geothermal resource producing technology); 1996 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (shinbu chinetsu shigen saishu gijutsu no kaihatsu / shinbu chinetsu shigen seisan gijutsu no kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The paper reported the results of the fiscal 1996 R and D of the deep geothermal resource collecting/producing technology. In the design of the total development, characteristics of the well mouth of the deep reservoir were examined to evaluate properties of deep geothermal resource, and the necessity of the pressure design, etc. were clarified. As to PTSD logging technology, conducted were improvement of PT probe, manufacture of a sonde of which S probe was integrated with memory/battery modules, and the actual well experiment. Concerning PTC monitoring technology, an experiment was carried out on a high temperature use optical fiber GI type, and it was shown that the type was on a commercial level. Further, a prototype sampler with 300degC heat resistance was trially manufactured, and a test to confirm its work was conducted in the well in the Corn Wall area of the U.K. As to the production control technology, studied was the arrangement of the production control technology for deep geothermal resource. Moreover, an experiment was made to examine the effect of metal ions coexisting when silica in the deep fluid precipitates. 46 refs., 107 figs., 38 tabs.

  8. Fiscal 1995 report on the results of the subsidy operation under the Sunshine Project on the development of a geothermal water use power plant, etc. Development of the binary cycle power plant (development of the measurement while drilling system for geothermal wells); 1995 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (binary cycle hatsuden plant no kaihatsu (chinetsusei kussakuji kotei joho kenchi system no kaihatsu))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The R and D were conducted of a detection system for measurement of data on the bottom hole of geothermal well, data transmission and signal processing, and an analysis system for well drilling trajectory control and well assessment while drilling of geothermal wells based on the data obtained by the detection system, and the results were reported of the technical development in fiscal 1995. In the development of the downhole detection unit, the following developments were conducted: mud pulse generator, bottomhole signal processor, mode switches, inclination information sensor, power source, measures against vibration/shock, sonde external equipment, tests to confirm heat resistance of electronic parts, and design/manufacture of testing devices. In the development of the surface detection unit, the development was made of experimental analysis program, interface program, and simulation. In the development of the analysis system, as a well trajectory control support system, made were a trajectory planning/display system and a trajectory prediction system. As a downhole assessment support system, made were a temperature analysis system and a pressure analysis system. 4 refs., 298 figs., 88 tabs.

  9. FY 1997 - FY 2000 reports on the results of the development of commercialization technology of the photovoltaic power system. Summary. R and D of the photovoltaic power generation utilization system/periphery technology (R and D of high reliability storage batteries); 1997-2000 nendo New sunshine keikaku seika hokokusho (Sokatsu ban). - Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu, Taiyoko hatsuden riyo system shuhen gijutsu no kenkyu kaihatsu (Koshinraisei chikuden sochi no kenkyu kaihatsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The R and D/evaluation were made from FY 1997 to FY 2000 of lead storage batteries that are applicable to the use for the absorption of abrupt power variations in photovoltaic power generation and peak shift/emergency use power source, and the results were summed up. In the study for prolonging the life, the following were carried out: development of the inexpensive corrosion-resistant lead alloy positive grid applicable to the photovoltaic power generation, development of the negative active material with a high sulfation control effect, selection of silica powder as electrolyte retainer, development of the charging control technology by the multi-stage constant current method, etc. As a result, energy density of the battery was more than 70W/L as a target, and the target life of 3,000 cycles was achieved in the life test. Further, cost reduction and deterioration judgment were studied. In the study of the group of batteries, a management system for group of batteries was developed. As a result of the 1-year field test, there were no problems on durability of the storage case, temperature difference among batteries, rise in temperature, etc. As to the developed seal type lead storage battery, the applicability to the photovoltaic power generation was acquired. (NEDO)

  10. Fiscal 1999 research report. Basic research for promotion of joint implementation programs (Comprehensive feasibility study on efficiency improvement of heat generation facility and heat network for district heating at middle and small cities in Moscow region, the Russian Federation - 2 model cities within the region); 1999 nendo Russia renpo Moscow shunai chusho toshi ni okeru chiiki danboyo netsu kyokyu shisetsu yusomo no koritsu kaizen keikaku sogo chosa hokokusho. Shunai 2 toshi wo model to suru

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The above-named effort aims to work out modification plans and to predict their energy saving, energy substituting, and greenhouse gas reduction effects, and thereby to scout out a project which will effectively utilize flexibility-ensuring 'joint implementation' for the attainment of greenhouse gas reduction levels defined at COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change). The results of assessment of this project based on the outcome of the survey show that (1) there is necessity for the project and that the presence of needs to be urgently satisfied is clear, that (2) energy saving, energy substituting, and greenhouse gas reduction effects are proved to exist and that the project is therefore an appropriate candidate for an activity to be implemented jointly, that (3) Russian agencies concerned are strongly interested in the project and that a sufficiently cooperative system will be available toward implementation, and that (4) there is an extremely large room for energy saving in the district heating oriented heat supply business in Russia and that probabilities are quite high that natural gas-fired turbine cogeneration plants capable of improving overall energy efficiency will enjoy extensive diffusion. (NEDO)

  11. FY 1999 report on the results of the project supplementary to the New Sunshine Project - Feasibility of coal hydrogasification technology in China. Investigational study of the social adaptability (Feasibility study of the international cooperation - Report of Beijing Research Institute of Coal Chemistry); 1999 nendo New Sunshine keikaku hojo jigyo (Bessatsu, Kokusai kyoryoku kanosei chosa Pekin Bai kagaku kenkyujo) hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu - Shakai tekigo sei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    For the purpose of establishing the coal hydrogasification technology which has a possibility of producing high-quality substitute natural gas in quantity and at low cost, an investigational study of the social adaptability was made. In this fiscal year, the following were carried out: outlook of energy supply/demand in China and the problems, natural gas resource and the plan for the use, actual state of the town gas business and the future plan, etc. As a part of the study, Beijing Research Institute of Coal Chemistry, China Coal Research Institute, made a survey under the research contract. As to the general situation of natural gas in China, report was made on the following: present situation of the development of natural gas resource in China, present situation of town gas in large cities of China, present situation and outlook of coal development and utilization in China, assessment of the coal mine area adaptable to coal hydrogasification, etc. In the survey of the area suitable for coal hydrogasification, report was made on the present situation and future of energy supply/demand in Shanghai, Shanxi, Shenfua and Xinjiang, present situation and future of town gas supply, etc. Survey/report were also made on the coal hydrogasification technology and the applicability. (NEDO)

  12. Fiscal 1997 report on the R and D project consignment from NEDO on industrial science and technology. R and D on total base technology for marine resources (Mn nodules mining system) (total system (experimental plan)); 1997 nendo sangyo kagaku gijutsu kenkyu kaihatsu jigyo Shin Energy Sangyo Gijutsu Sogo Kaihatsu Kiko itaku. Kaiyo shigen sogo kiban gijutsu no kenkyu kaihatsu (mangan dankai saiko system) seika hokokusho (total system (jikken keikaku) hen)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    Study was made on the design of experiments for confirming the technological and economical feasibility of commercial production of Mn nodules. An experimental sea area was selected considering Mn nodule characteristics such as concentration, continuity of nodule distribution and nodule size, and sea bottom topographic features such as flatness and exposed bed rock disturbing traveling of nodule collectors. The experimental plan was decided on the basis of the survey and study on an experimental scale, various requirements, weather and sea weather features of the sea area, and sea bottom conditions. Based on the experimental plan, various verification tests and simulation analyses were carried out, and functions of various equipment were confirmed. The conceptual design of a mining system assumed both pump-lift and air-lift systems, and yearly production rates of 2 and 3 million tons by 2 mining barges, and summarized main points of every system. As the evaluation result, the future direction of commercial production of Mn nodules was clarified to a certain extent. 5 figs., 21 tabs.

  13. Fiscal 1996 report on the results of the subsidy operation under the Sunshine Project on the development of a geothermal water use power plant, etc. Development of the binary cycle power plant (development of the measurement while drilling system for geothermal wells); 1996 nendo New Sunshine keikaku hojo jigyo seika hokokusho. Nessui riyo hatsuden plant nado kaihatsu (binary cycle hatsuden plant no kaihatsu (chinetsusei kussakuji kotei joho kenchi system no kaihatsu))

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The R and D were carried out of a detecting system for measurement of data on the bottom of geothermal well, data transmission and signal processing, and an analysis system for well drilling trajectory control and well assessment while geothermal well drilling based on the data obtained by the detecting system. The paper reported the results of the technology development in fiscal 1996. In the development of the detecting system, improvement/design were conducted on a mud pulse generator constituting sonde, well bottom signal processing equipment, mode switch and inclined information sensor, and the system equivalent to the actual one was manufactured to conduct a running test at high temperature/pressure. Moreover, a test to confirm heat resistance of electronic parts was made for further improvement in heat resistance of the sonde, in order to obtain the data. In the development of an analysis system, conducted were enhancement of operability of the planning/indication portions of the well drilling trajectory supporting system, improvement of the data intake system, etc. In relation to the well assessment supporting system, carried out were heightening of operability of the temperature analysis portion and confirmation of accuracy increase. 5 refs., 253 figs., 72 tabs.

  14. New Sunshine Program for fiscal 2000. Development of photovoltaic power system commercialization technology (Development of ultrahigh-efficiency crystalline compound solar cell manufacturing technology - Survey and research of analysis of commercialization - Separate Volume: Survey of next-generation ultrahigh-efficiency solar cell system); 2000 nendo New sunshine keikaku seika hokokusho. Taiyoko hatsuden system jitsuyoka gijutsu kaihatsu - Chokokoritsu kessho kagobutsu taiyo denchi no seizo gijutsu kaihatsu (Jitsuyoka kaiseki ni kansuru chosa kenkyu - Bessatsu : Jisedai chokokoritsu taiyodenchi system ni kansuru chosa)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the preparation of a proposition concerning future research and development, surveys and studies were conducted centering about efficiency enhancement and cost reduction for the next generation ultrahigh-efficiency solar cell system. For improving the efficiency of the crystalline compound solar cell, studies were made about the prospects of the embodiment of a 3-junction and 4-junction types and of an increase in conversion efficiency expected to realize thanks to their light condensation behavior. It was inferred that anticipation of 29-47% conversion efficiency in 1 to 4-joint cells was theoretically acceptable. Four-joint structure cell fabrication would be a challenging task but would bring about an conversion efficiency of approximately 47% thanks to enhanced light condensation capability. As for cost reduction through the use of light condensation technology, surveys of overseas trends showed that the condensation-enhanced photovoltaic power system was characteristically fit for lower-price production. As for condensation and tracking systems, studies were made about cost calculation models of organizations involved in the United States and Europe, and then it was found that cost reduction in the optical system for condensation and in the tracking mechanism would be mandatory for the achievement of 75 yen/W. (NEDO)

  15. FY 2000 report on the results of the project supplementary to the New Sunshine Project - Feasibility of coal hydrogasification technology in China. II - Final report. Investigational study of the social adaptability (Feasibility study of the international cooperation - Report of Beijing Research Institute of Coal Chemistry); 2000 nendo New Sunshine keikaku hojo jigyo (Bessatsu kokusai kyoryoku kanosei chosa Pekin Bai kagaku kenkyujo) hokokusho. Sekitan suiso tenka gaska gijutsu kaihatsu - Shakai tekigo sei ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    For the purpose of establishing the coal hydrogasification technology which has a possibility of producing high-quality substitute natural gas in quantity and at low cost, an investigational study of the social adaptability was made. In this fiscal year, the following were carried out: natural gas resource and the plan for the use in China, actual state of the town gas business and the future plan, etc. As a part of the study, Beijing Research Institute of Coal Chemistry, China Coal Research Institute, made a survey under the research contract. As a result of the survey, the following was found out: In Xinjiang and Urumchi, Uigur Autonomous Region, there is an abundant coal resource that is suitable for coal hydrogasification, the transportation pipeline of natural gas had been constructed, and public facilities are prepared, and therefore, both cities are suitable for the construction of coal hydrogasification plant. Datong, Shanxi Province, is a largest city of coal production, enables the long-term coal supply for coal hydrogasification, and has a plan for remodeling of old facilities and construction of new facilities for the introduction of natural gas, and therefore, the city is suitable for the construction of coal hydrogasification plant. (NEDO)

  16. Lack of endothelial nitric oxide synthase aggravates murine accelerated anti-glomerular basement membrane glomerulonephritis

    NARCIS (Netherlands)

    Heeringa, P; van Goor, H; Itoh-Lindstrom, Y; Maeda, N; Falk, RJ; Assmann, KJM; Kallenberg, CGM; Jennette, JC

    Nitric oxide (NO) radicals generated by endothelial nitric oxide synthase (eNOS) are involved in the regulation of vascular tone. In addition, NO radicals derived from eNOS inhibit platelet aggregation and leukocyte adhesion to the endothelium and, thus, may have anti-inflammatory effects. To study

  17. Tetrahydrobiopterin Has a Glucose-Lowering Effect by Suppressing Hepatic Gluconeogenesis in an Endothelial Nitric Oxide Synthase–Dependent Manner in Diabetic Mice

    Science.gov (United States)

    Abudukadier, Abulizi; Fujita, Yoshihito; Obara, Akio; Ohashi, Akiko; Fukushima, Toru; Sato, Yuichi; Ogura, Masahito; Nakamura, Yasuhiko; Fujimoto, Shimpei; Hosokawa, Masaya; Hasegawa, Hiroyuki; Inagaki, Nobuya

    2013-01-01

    Endothelial nitric oxide synthase (eNOS) dysfunction induces insulin resistance and glucose intolerance. Tetrahydrobiopterin (BH4) is an essential cofactor of eNOS that regulates eNOS activity. In the diabetic state, BH4 is oxidized to 7,8-dihydrobiopterin, which leads to eNOS dysfunction owing to eNOS uncoupling. The current study investigates the effects of BH4 on glucose metabolism and insulin sensitivity in diabetic mice. Single administration of BH4 lowered fasting blood glucose levels in wild-type mice with streptozotocin (STZ)-induced diabetes and alleviated eNOS dysfunction by increasing eNOS dimerization in the liver of these mice. Liver has a critical role in glucose-lowering effects of BH4 through suppression of hepatic gluconeogenesis. BH4 activated AMP kinase (AMPK), and the suppressing effect of BH4 on gluconeogenesis was AMPK-dependent. In addition, the glucose-lowering effect and activation of AMPK by BH4 did not appear in mice with STZ-induced diabetes lacking eNOS. Consecutive administration of BH4 in ob/ob mice ameliorated glucose intolerance and insulin resistance. Taken together, BH4 suppresses hepatic gluconeogenesis in an eNOS-dependent manner, and BH4 has a glucose-lowering effect as well as an insulin-sensitizing effect in diabetic mice. BH4 has potential in the treatment of type 2 diabetes. PMID:23649519

  18. Exhaled nitric oxide - circadian variations in healthy subjects

    Directory of Open Access Journals (Sweden)

    Antosova M

    2009-12-01

    Full Text Available Abstract Objective Exhaled nitric oxide (eNO has been suggested as a marker of airway inflammatory diseases. The level of eNO is influenced by many various factor including age, sex, menstrual cycle, exercise, food, drugs, etc. The aim of our study was to investigate a potential influence of circadian variation on eNO level in healthy subjects. Methods Measurements were performed in 44 women and 10 men, non-smokers, without respiratory tract infection in last 2 weeks. The eNO was detected at 4-hour intervals from 6 a.m. to 10 p.m. using an NIOX analyzer. We followed the ATS/ERS guidelines for eNO measurement and analysis. Results Peak of eNO levels were observed at 10 a.m. (11.1 ± 7.2 ppb, the lowest value was detected at 10 p.m. (10.0 ± 5.8 ppb. The difference was statistically significant (paired t-test, P Conclusions The daily variations in eNO, with the peak in the morning hours, could be of importance in clinical practice regarding the choice of optimal time for monitoring eNO in patients with respiratory disease.

  19. Metabolic Host Responses to Malarial Infection during the Intraerythrocytic Developmental Cycle

    Science.gov (United States)

    2016-08-08

    supply for other biological processes in the RBC. In contrast to the relatively high PGK flux, we obtained zero ratios for diphosphoglycerate ...iRBCs; DPGase, diphosphoglycerate phosphatase; DPGM, diphosphoglycero mutase; ENO, enolase; FBA, fructose bisphosphate aldolase; GAPD, glyceraldehyde-3...1107 kb) Abbreviations cRBC, cocultured uninfected RBCs; DPGase, diphosphoglycerate phosphatase; DPGM, diphosphoglycero mutase; ENO, enolase; FAD

  20. Measurement of O-GlcNAcylated endothelial nitric oxide synthase by using 2',5'-ADP-Sepharose pull-down assay.

    Science.gov (United States)

    Long, Yang; Yan, Jianghong; Luo, Suxin; Liu, Zhenguo; Xia, Yong

    2017-11-15

    Endothelial nitric oxide synthase (eNOS) plays central roles in cardiovascular regulation and disease. eNOS function is critically affected by O-linked N-acetylglucosamine (O-GlcNAc) modification. The present method for measuring O-GlcNAcylated eNOS relies on immunoprecipitation. Such method exhibits low detection efficiency and is also costly. We here report a simplified assay by employing the high binding affinity of eNOS with the 2',5'-ADP-Sepharose resins. Together with the O-GlcNAc antibody, this assay readily allows the detection of O-GlcNAcylated eNOS in both cultured endothelial cells and rat vascular tissues. By using this assay, we demonstrate that eNOS O-GlcNAcylation is markedly elevated in the vessels of diabetic rats. Thus, a 2',5'-ADP-Sepharose-based pull-down assay is developed to measure O-GlcNAcylated eNOS. This assay is simple and efficient in detecting O-GlcNAcylated eNOS in cultured cells and animal tissues under both normal and disease conditions. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Endothelial nitric oxide synthase gene Glu298Asp polymorphism ...

    African Journals Online (AJOL)

    Administrator

    2011-09-12

    Sep 12, 2011 ... Figure 1. The Glu298Asp polymorphism of eNOS gene was shown by .... mechanisms by which eNOS Asp298 polymorphism ... Asp298 is exposed to selective proteolytic cleavage in ... grounds, inclusion and exclusion criteria for PE women ... attention to meta analysis study, it is more probable that.

  2. Carbon monoxide releasing molecule induces endothelial nitric oxide synthase activation through a calcium and phosphatidylinositol 3-kinase/Akt mechanism.

    Science.gov (United States)

    Yang, Po-Min; Huang, Yu-Ting; Zhang, Yu-Qi; Hsieh, Chia-Wen; Wung, Being-Sun

    2016-12-01

    The production of nitric oxide (NO) by endothelial NO synthase (eNOS) plays a major role in maintaining vascular homeostasis. This study elucidated the potential role of carbon monoxide (CO)-releasing molecules (CORMs) in NO production and explored the underlying mechanisms in endothelial cells. We observed that 25μM CORM-2 could increase NO production and stimulate an increase in the intracellular Ca 2+ level. Furthermore, ethylene glycol-bis(β-aminoethyl ether)-N,N,N',N'-tetra acetic acid caused CORM-2-induced NO production, which was abolished by 1,2-bis(2-aminophenoxy) ethane-N,N,N',N'-tetraacetic acid tetraacetoxy-methyl ester (BAPTA-AM), indicating that intracellular Ca 2+ release plays a major role in eNOS activation. The inhibition of the IP3 receptor diminished the CORM-2-induced intracellular Ca 2+ increase and NO production. Furthermore, CORM-2 induced eNOS Ser 1179 phosphorylation and eNOS dimerization, but it did not alter eNOS expression. CORM-2 (25μM) also prolonged Akt phosphorylation, lasting for at least 12h. Pretreatment with phosphatidylinositol 3-kinase inhibitors (wortmannin or LY294002) inhibited the increases in NO production and phosphorylation but did not affect eNOS dimerization. CORM-2-induced eNOS Ser 1179 phosphorylation was intracellularly calcium-dependent, because pretreatment with an intracellular Ca 2+ chelator (BAPTA-AM) inhibited this process. Although CORM-2 increases intracellular reactive oxygen species (ROS), pretreatment with antioxidant enzyme catalase and N-acetyl-cysteine did not abolish the CORM-2-induced eNOS activity or phosphorylation, signifying that ROS is not involved in this activity. Hence, CORM-2 enhances eNOS activation through intracellular calcium release, Akt phosphorylation, and eNOS dimerization. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Flavonoids from artichoke (Cynara scolymus L.) up-regulate endothelial-type nitric-oxide synthase gene expression in human endothelial cells.

    Science.gov (United States)

    Li, Huige; Xia, Ning; Brausch, Isolde; Yao, Ying; Förstermann, Ulrich

    2004-09-01

    Nitric oxide (NO) produced by endothelial nitric-oxide synthase (eNOS) represents an antithrombotic and anti-atherosclerotic principle in the vasculature. Hence, an enhanced expression of eNOS in response to pharmacological interventions could provide protection against cardiovascular diseases. In EA.hy 926 cells, a cell line derived from human umbilical vein endothelial cells (HUVECs), an artichoke leaf extract (ALE) increased the activity of the human eNOS promoter (determined by luciferase reporter gene assay). An organic subfraction from ALE was more potent in this respect than the crude extract, whereas an aqueous subfraction of ALE was without effect. ALE and the organic subfraction thereof also increased eNOS mRNA expression (measured by an RNase protection assay) and eNOS protein expression (determined by Western blot) both in EA.hy 926 cells and in native HUVECs. NO production (measured by NO-ozone chemiluminescence) was increased by both extracts. In organ chamber experiments, ex vivo incubation (18 h) of rat aortic rings with the organic subfraction of ALE enhanced the NO-mediated vasodilator response to acetylcholine, indicating that the up-regulated eNOS remained functional. Caffeoylquinic acids and flavonoids are two major groups of constituents of ALE. Interestingly, the flavonoids luteolin and cynaroside increased eNOS promoter activity and eNOS mRNA expression, whereas the caffeoylquinic acids cynarin and chlorogenic acid were without effect. Thus, in addition to the lipid-lowering and antioxidant properties of artichoke, an increase in eNOS gene transcription may also contribute to its beneficial cardiovascular profile. Artichoke flavonoids are likely to represent the active ingredients mediating eNOS up-regulation.

  4. `Joint Research and Development of Industrial Technology,` an international research collaboration for fiscal 1997. Utilization of 3D-woven C/C composite materials to machine components; 1997 nendo kokusai kenkyu kyoryoku jigyo `sangyo kiban gijutsu kyodo kenkyu kaihatsu`. Sanjigen ori C/C composite zairyo no kikai buhin eno oyo ni kansuru kenkyu seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-03-01

    A polygonal mirror in a printer and the main shaft of a high-speed milling machine are used as models for the development of technology for applying C/C (carbon/carbon) composite materials to machine components that are required to turn at high speeds. Various C/C composites are tested for flexural strength and thermal expansion for the designing and manufacturing of C/C composites for the polygonal mirror and main shaft. The first coating on the C/C composite is deposited by laser/plasma hybrid spraying, and is a Mo coating. A spraying robot is experimentally built for homogeneous coating. In the case of polygonal mirror, an Al coating is deposited further by the gas-deposition method. The polygonal mirror proves excellent in both dimension and reflectance, and attains the target speed of 45,000rpm. In the case of milling machine main shaft, however, it is not strong enough to withstand 40,000rpm although it is a success from a viewpoint of coating technology and manufacturing technology. 15 refs., 33 figs., 13 tabs.

  5. Application of low bitrate image coding to surveillance of electric power facilities. Part 1. Proposal of low bitrate coding for surveillance of electric power facilities and examination of facilities region extraction method; Denryoku setsubi kanshi eno tei rate fugoka hoshiki no tekiyo. 1. Setsubi kanshiyo fugoka hoshiki no teian to setsubi ryoiki chushutsuho no kento

    Energy Technology Data Exchange (ETDEWEB)

    Murata, H.; Ishino, R. [Central Research Institute of Electric Power Industry, Tokyo (Japan)

    1996-03-01

    Current status of low bitrate image coding has been investigated, and a low bitrate coding suitable for the surveillance of electric power facilities has been proposed, to extract its problems to be solved. For the conventional image coding, the waveform coding has been used by which the images are processed as signals. While, for the MPEG-4, a coding method with considering the image information has been proposed. For these coding methods, however, image information lacks details primarily, when lowering the bitrate. Accordingly, these methods can not be applied when the details in the images are important, such as in the case of surveillance of facilities. Then, the coding method has been proposed by expanding the partially detailed coding, and by separating constituent images of facilities, such as power cables and steel towers, designated by operators. It is the special feature of this method that the method can easily respond to the low bitrate and the detailed information can be conserved by using the structure extraction coding for the designated partial image which is generally processed by the low bitrate waveform coding. 29 refs., 17 figs., 1 tab.

  6. Report on achievements in fiscal 1998. Venture business growing type consortium - small business creating infrastructure (Development of ultra-high efficiency cultivation system for Hyphomycetes, and application of the system to plant device to manufacture fermentative foods); 1998 nendo itojokin no chokoritsu tairyo baiyo system no kaihatsu to kinosei hakko sho0kuhin seizo plant kiki eno tekiyo seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    This project has noticed the membrane surface liquid culture method, and researched and developed the following themes with an objective to commercialize the membrane surface liquid culture system and develop novel fermentative foods using this system. Cultivation of Beni-koji bacteria (solid culture of M. pilosus k) is taken up in the model cultivation system. (1) establishment of the membrane surface liquid culture system and development of devices, (2) elucidation of cultivation characteristics of the membrane surface liquid culture system and optimization of the cultivating conditions, and (3) development of fermentative foods. In Item (1), such problems were solved as automation of bacteria planting, long-term pasteurized cultivation, and assurance of clean cultivation broth. In Item (2), it was discovered most suitable that maltose concentration is about 5%, glutamic acid concentration is about 50 mM, the initial culture medium pH is about six, and the cultivation temperature is 30 degree C. In item (3), as a result of mixing this red coloring matter containing cultivation broth into preparation of Miso (bean paste) and soy sauce, products having high {gamma}-Aminobutyric acid and monacholin k content were developed. In addition, while Beni-koji made by solid cultivation had peculiar taste and odor, this drawback was eliminated by using this coloring matter containing cultivation broth. This has made differentiation from conventional products possible. (NEDO)

  7. Fiscal 1999 research result report on energy and environment technology demonstration research support project (International joint demonstration research project). Improvement of long-distant power transmission efficiency and reliability, and its environmental impact assessment; 1999 nendo chokyori soden hoshiki ni kansuru soden koritsu to soden shinraido no kojo oyobi kankyo eno eikyo hyoka seika hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Japan-Russia international joint research was made on overhead ultrahigh-voltage DC power transmission lines for transmission loss reduction and reliability improvement, and an optimum international power supply cable system, considering energy saving and environment conservation. Using the European-Russian DC power transmission line of {+-}500kV and 4GW as a model, comparison was made between a model using Russian round strands and glass insulators and a model using Japanese low-loss wires and insulators. As for improvement of the reliability in cold districts, Russian design techniques for tower structure and ice loading were reasonable to counteract galloping oscillation and ice load. In evaluation and selection of optimum underground and marine cables, study was made on cable specifications using the Turkey-Russia power transmission route as a model. The environmental assessment result of these cables showed that XLPE cable under development is optimum. (NEDO)

  8. Sensing of subsurface faults based on an imaging technique for teleseismic waveform data. 2. Feasibility study for application to oblique incidence, multi-event and noise data; Enchi jishin hakei data wo mochiita chika kozo imaging ni yoru chichu danso kenshutsu no kokoromi. 2. Naname nyusha, multi event, noise wo fukumu hakei eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Murakoshi, T; Takenaka, H; Saita, T [Kyushu University, Fukuoka (Japan). Faculty of Science; Suetsugu, D [Building Research Institute, Tokyo (Japan); Furumura, T [Hokkaido University of Education, Sapporo (Japan)

    1996-05-01

    An examination was made on the method in which imaging of subsurface was carried out with teleseismic waveform data for sensing of faults. In the examination, an experiment was done on the sensing of faults with higher precision, by applying oblique incidence as well as perpendicular upward incidence of SH plane waves, and thereby stacking the imaging in plural events. In numerical experiments, 28 observation points were arranged at 500m spaces apart on the surface, and the incident waves were made the SH plane waves having a bell-shaped time function, with incidence made at an angle varied as 0{degree}, +15{degree} and -15{degree} from the lowest layer of a model. In the calculation of the wave motion field, a difference calculus with secondary accuracy was used for both time and space. In addition, data was prepared with a random noise added to a synthesized waveform to be used as observation data. The calculated waveform data were likened to the observation waveform, to which the method for imaging faults was applied. Consequently, it was noted that satisfactory results were obtained compared with the case where faults were sensed by one event alone. 5 refs., 4 figs.

  9. FY1998 survey on IEA international cooperation project on demonstration and survey of new load leveling methods (participation in the IEA/DSM task VI); 1998 nendo fuka heijunka shinshuho jissho chosa IEA kokusai kyoryoku jigyo 'IEA/DSM task 6 eno sanka ni tsuite' chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    It is intended to participate in the IEA international cooperation project related to DSA, exchange items of information, and promote demonstration and survey of new load leveling methods. The existing and newly proposed DSM mechanisms as the achievement of the previous tasks were put into order. The arena of information exchange and discussions was prepared through use of the Internet homepage for the IEA/DSM implementation agreement. Necessary official policies were also made available. Points of precautions when the mechanisms of other countries are used in Japan: the key to the success depends on social or cultural situations that work as the base; therefore, comparisons and analyses are necessary on such elements as customers as the object, energy projects and governments; compatibility of the situation and pattern of the demand side with the DSM technologies governs the reasonability thereof; the types of the mechanisms are narrowed down by size of the customer division, consumption pattern, electric power quality and safety, and needs on the flexibility; proliferation levels of the DSM technologies determine the appropriate mechanisms; and how the DSM is conceived against the final consumption is governed by the conception by both of the customers and the government. (NEDO)

  10. Research on PV system application on residences. Part 1. Report on the systems and PV measurement results of an experimental passive solar house; Taiyoko hatsuden system no jutaku eno oyo ni kansuru kenkyu. 1. Taisho tatemono taiyo to taiyoko hatsuden system keisoku kekka

    Energy Technology Data Exchange (ETDEWEB)

    Ishihara, O.; Sakai, K.; Hirakawa, M. [Kumamoto University, Kumamoto (Japan). Faculty of Engineering

    1997-11-25

    System of the house is outlined, and warming performance and photovoltaic power generation system energy performance are taken up. It is a one-storied meeting hall situated in an apartment area, whose heat loss factor is 2.59kcal/m2hdegC. Ninety hybrid solar cells provided with circulating air heat collectors are installed on the east-side of the roof, interconnected to the commercial power system. In the daytime in summer, the house is fully insulated from solar radiation, with the room temperature kept a little lower than the open air temperature. The range of daily change in the room temperature is narrow, providing a comfortable residential space. When the windows are opened in the evening, cool air comes into the room to replace the warm air inside, reducing the difference in temperature between the inside and outside of the room. In winter, insolation time is short on the east side of the roof which finds itself out of the sun. Under the circumstances, the system outputs but a little and the quantity sold is quite small in winter. But, in summer, sale of power can be practicable, thanks to exposure to sufficient sunshine. The inverter rated at 3.5kW attains a 90% or higher operating rate in the presence of an input of power of 0.5kW or more. 4 refs., 10 figs.

  11. Fiscal 2000 achievement report on the venture business assisting type regional consortium - Minor business creation base type. Development of 1-chip multifunctional motion sensor and its application to intelligent module; 2000 nendo chiiki consortium kenkyu kaihatsu jigyo seika hokokusho. 1 chip gata takino undo sensor no kaihatsu to intelligent module eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    The aim is to embody an intelligent micromodule for sensing bodily motions. For this purpose, technologies were established for high accuracy/high aspect ratio etching of crystals and for detecting angular velocity and acceleration, and a 1-chip multifunctional motion sensor was developed. The results of the efforts are briefly described below. A 1-chip multifunctional motion sensor (device size: 16 times 6 times 0.3mm) was developed, capable of simultaneously detecting uniaxial acceleration and uniaxial angular velocity, and an operating circuit was established for the detection. Using the 1-chip multifunctional motion sensor, a wrist watch type intelligent module was developed, capable of discriminating between various patterns of human behavior (walking, jogging, desk work, etc.). An intelligent module and the host computer were connected by wire or radio enabling the real-time observation of a patient's kinetic behavior, and this helped develop an application program allowing the quantification of the rate of recovery of patients undergoing rehabilitation. Using an intelligent module, an application program was developed enabling a laryngeal patient to establish communication by a physical action in case of emergency. (NEDO)

  12. Report on a survey in fiscal 1999. Survey and research on the status quo of environmental industries and transfer of environmental technology to foreign countries; 1999 nendo kankyo sangyo no genjo to kaigai gijutsu iten eno taio ni kansuru chosa kenkyu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Active contributions of private business enterprises are expected for international approaches to global environment problems. The objectives of this survey are: to extract and put into order various issues in practically using, proliferating, and transferring the environmental technologies developed or possessed by private business enterprises in Japan; and to survey and research the institutional and financial systems as measures to solve the problems. Chapter 1 identifies and puts into order the Japanese approaches toward the global environment problems, particularly the reduction of greenhouse effect gas emission, and the problems carried by the private business enterprises. Chapter 2 takes up environmental technologies being at the demonstration phase and the practical application phase to investigate possibilities of transfer of the technologies to foreign countries. It considers the problems in transferring the technologies, and the means of solution thereof, describing simultaneously the past successful cases. Chapter 3 indicates the measures that Japan should work on when promoting the transfer of its environmental technologies. Chapter 4 surveys and studies the ways the assistance measures in financial aspect should be. Chapter 5 summarizes expectations on the roles to be played by NEDO. (NEDO)

  13. Detection of strain behavior during phase-transformation in welds by the laser speckle method. Report 3. Application of the laser speckle method to strain masurement in the welding process; Reza supekkuru ho ni yoru yosetsubu no sohentai tojo no hizumi kenshutsu. 3. Reza supekkuru ni yoru hizumi sokuteiho no yosetsu eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Muramatsu, Y.; Kuroda, S. [National Research Inst. for Metals, Tsukuba, Ibaraki (Japan); Gross, H-G. [Rostock Univ., Rostock (Germany)

    1996-11-05

    It corresponds to an information relating to defect formation due to residual stress and its accompanying defect formation to find out the period of phase-transformation and expansion volume on the transformation forming at welding. In order to estimate texture of the heat affected zone, there is an SH-CCT diagram, which is important on weld metallurgy. However, this is formed by giving a thermal recycling to a small size specimen under stress-free, which has some problems to estimate the transformation starting period in actual welding. And, the expansion volume containing the transformation cannot be found out directly by this. In this study, as the first step adaptable to this problem with laser speckle method measurable with non-contact and high precision, a linear heating with TIG to a SUS304 stainless steel thin plate without transformation was executed at first, the strain behavior accompanied with it was confirmed. Secondly, using a thin plate of 9% Ni steel showing any transformation at comparatively low temperature, probability of a phase transformation detection was investigated on a way of cooling by executing resemble linear heating. As a result, the laser speckle method was confirmed to be adaptable to this problem. 14 refs., 17 figs., 1 tab.

  14. FY 1995 development of fluorinated hydriding alloys with multi functional and functionally-graded surface and their application to energy conversion devices; 1995 nendo keishagata fukugo kino wo hyomen ni motsu suiso kyuzo gokin no kaihatsu to energy henkan gijutsu eno oyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The project is the extended researches of a fluorination technique invented by the project leader (Suda) for improving the surface properties and characteristics of conventional hydriding alloys from the following viewpoints; (1) To investigate the roles of fluorinated surface during hydrogen uptake both in the gas-solid and the electrochemical reactions. (2) To elucidate the factors which increase the protective nature of the surface. (3) To develop a material design procedure for synthesizing thin layer of functionally graded surface which is composed of metallic Ni and the fluoride compound. (1) An advanced fluorination technique was developed to incorporate metallic Ni in the surface fluoride layer. (2) Metallic Ni was successfully distributed in a functionally graded manner in the Surface fluoride layer. (3) Through the technique developed, the following properties and characteristics were successfully donated in the fluorinated hydriding alloys such as AB{sub 5}, AB{sub 2}, and AB; (3-1)Surface oxides which act as the resistant layer to the hydrogen up take was completely eliminated to result in the enhancement of the initial activation characteristics. (3-2) Hydrogen selectivity and permeability was greatly improved. (3-3) Surface protective nature against the impurity gases and contaminants was significantly improved. (3-4) Initial activation characteristics both in the gas-solid and the electrochemical reactions were distinguishably improved. (3-5) Fluorinated surface was found to function as the catalyst for a methanation reaction between the CO{sub 2} gas adsorbed over the fluorinated surface and the monatomic hydrogen absorbed in the metal lattice of the crystalline structure of the hydriding alloys. (4) A technique was developed for increasing the specific surface area and decreasing the specific surface diameter of the fluorinated hydriding alloy articles. (NEDO)

  15. Acoustic excitation of diffusion flames with coherent structure in a plane shear layer. ; Application of active combustion control to two-dimensional phase-locked arranging measurements. Soshiki kozo wo tomonau heimen sendai kakusan kaen no onkyo reiki. ; Nijigen iso heikin bunpu sokutei eno active nensho seigyo no oyo

    Energy Technology Data Exchange (ETDEWEB)

    Ishino, Y.; Kojima, T.; Oiwa, N.; Yamaguchi, S. (Nagoya Institute of Technology, Nagoya (Japan))

    1993-11-25

    The acoustic excitation of a plane diffusion flame enhances the periodicity of organized eddy controlled combustion. In this study, to clarify an effectiveness of application of active combustion control, phase characteristics of the excited eddy flames with high periodicity have been examined. A computer-aided phase-locked averaging method was employed to obtain graphical two-dimensional contour maps of the instantaneous profiles of temperature and CH emission. Both maps consisting of eight consecutive phases indicated clearly not only the periodic behavior of the organized eddy flame, but also the gas dynamic properties peculiar to those flames with coherent structure. In addition, the profiles of local contribution of the sound field to the combustion process were examined by calculating the two-dimensional distribution of the local Rayleigh index. Calculation results of the two-dimensional distribution of the local Rayleigh index indicated that the organized eddy flames have high sensitivity to sound, and play an important role in an interaction of sound and flame. 6 refs., 9 figs.

  16. Achievement of 900kgf/cm[sup 2] super workable high strength concrete with belite Portland cement (elevator building of cement silo in Chichibu cement). 2. ; Application to the actual structure. Ko belite kei cement de 900kgf/cm[sup 2] wo tassei (Chichibu cement cement silo no elevator to). 2. ; Jitsukozobutsu eno tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Yoda, K.; Sakuramoto, F. (Kajima Corp., Tokyo (Japan))

    1993-08-01

    For the purpose of rationalization of concrete works, the super workable high strength concrete was applied to the underground part of elevator building of cement silo in the Kumagaya Works, Chichibu Cement, and was successfully put into practice. Quality control values of the super workable high strength concrete were 65[plus minus]5cm in the slump flow and 900kgf/cm[sup 2] in the compressive strength at the age of 28 days. Addition of the admixture was 1.25% of the unit cement amount. Based on the linear correlation between the slump flow and mixer load immediately before discharge, the slump flow was controlled by the mixer load. Property of the fresh concrete, fluidity, compacting property, material segregation resistance property, and strength property were examined by using a sidewall test model. For all tests, satisfactory properties were obtained. Subsequently, the actual structure was successfully constructed. As a result, laborsaving and improvement of productivity were confirmed for the super workable high strength concrete work. 3 refs., 8 figs., 4 tabs.

  17. Mercury free zinc alloy powder for alkaline manganese battery. 2. Effect of additive species to zinc particle on suppressing hydrogen gas evolution; Arukari mangan denchiyo mukoka aen gokin funmatsu. 2. Suiso gas hassei ni oyobosu aen ryushi eno tenka genso no yokusei koka

    Energy Technology Data Exchange (ETDEWEB)

    Yano, M.; Fujitani, S.; Nishio, K. [Sanyo electric Co. Ltd., Osaka (Japan); Akai, Y.; Kurimura, M. [Sanyo Excell Co. Ltd., Tottori (Japan)

    1997-08-05

    In order to make alkaline manganese batteries mercury-free and suppress hydrogen gas generation, investigations were given on the effect of additive species on modification of zinc particles present on negative electrode surface. Mercury with high hydrogen overvoltage has been added conventionally, but the mercury can cause an environmental problem. Surface modification by using indium exhibited hydrogen gas generation suppressing effect. With the surface modification amount of 0.10% by weight or more, the suppressing effect is saturated, reducing the effect to 50% of that of mercury. Surface-modifying the bismuth added zinc particles with indium showed greater suppressing effect than the case where each element is used independently. Zinc-indium (0.10% by weight) - bismuth (0.025% by weight) based alloy powder showed the same hydrogen generation suppressing effect as zinc-mercury (0.15% by weight) alloy powder. A sealed test battery using this alloy powder in negative active material exhibited a discharge capacity of 1700 mAh similarly to the initial stage even after having been stored for 20 days at 60 degC. Self-discharge characteristics equivalent to that of zinc-mercury (0.15% by weight) based alloy powder were obtained. An environment compatible dry cell battery containing no mercury whatsoever was developed successfully. 18 refs., 6 figs., 1 tab.

  18. FY 1999 report on the results of the investigational study on the promotion of application of aluminum materials to automobiles by the development of low-cost aluminum materials and aluminum resource recycling technology; 1999 nendo tei cost aluminium zai oyobi arumi shigen junkan gijutsu no kaihatsu ni yoru jidosha eno aluminium zai tekiyo suishin ni kansuru chosa kenkyu hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    Presently, the aluminum demand in Japan is approximately 3.8 million tons, and the aluminum discharged as scrap reaches approximately 1.7 million tons/year. Out of the discharged scrap, 54% is recovered as the secondary metal, and the rest, 0.77 million tons, is not recovered and dumped for land reclamation. In future, if the present cascade type recycling goes on, it is predicted that a gap between supply and demand of about 0.5 million tons will arise. To cope with this problem, the following are the measures to be taken : 1) development of the technology to promote the use of recycled aluminum metal for automobiles in which a lot of aluminum is most likely to be used because of the increasing fuel consumption, etc. 2) establishment of a recycling system by which the waste sash discharged in quantity from the construction field is again used as sash. From the two points of view, which are needed in the case of using a lot of aluminum for automobiles, the heightening of competitiveness in the aluminum industry and the recycling in which the aluminum expanded materials used for automobiles are efficiently recycled as expanded materials in the recycling economic system, this survey extracted problems and made proposals, overlooking the state of the aluminum use in automobiles, state of the treatment of used cars, state of manufacturing/processing technology of aluminum products. (NEDO)

  19. FY1995 establishment of extracellular matrix engineering by the combination of genetic engineering and polymer engineering and the application to super-bioartifical liver; 1995 nendo idenshi kogaku to kobunshi kogaku wo yugoshita atarashii saibogai matrix kogaku no sosei to super bio jinko zoki kaihatsu eno tenkai

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    Cellular and tissue engineering for bioartificial organs need lots of information about extra-cellular matrices and cytokines network which play important roles for the regulation of cellular function. In order to develop high performance artificial livers, we made establishment of extracellular matrix (ECM) engineering by the combination of genetic engineering and polymer engineering. We designed a superglycoprotein-like polymer (PVLA) as a specific model ligand to asialoglycoprotein receptors (ASGP-R) on hepatocytes. Hepatocytes morphology was remarkably affected by PVLA concentration for coating on polystyrene dishes. In addition, hepatic functions such as differentiation and proliferation were closely related with cell morphology. Especially, round hepatocytes on the polystyrene surface coated with high concentration of PVLA were found to reconstruct 3D liver-like tissue stimulated by EGF. It turned out that the adsorptive states of PVLA polymeric micells can switch the function of EGF to be motogenic or mitogenic. The mechanisms of 3D-tissue formation on two types of substrata mediated by ASGP-R were examined. The proliferation and cell death (apoptosis) in hepatitis of hepatocytes were also examined in the viewpoint of cytokine network such as TNF - {alpha} and interferon-{gamma}. The highly efficient gene-transfection into hepatocytes was also successfully made using PVLA as ECM for cell attachment. As one of the trials to clarify liver cells society formation the mechanism of the final differentiation of kupffer cells and the role of HGF in embryonic construction of liver were successfully examined. (NEDO)

  20. Přístup ke spravedlnosti ve věcech životního prostředí a Soudní dvůr EU: navzdory Aarhuské úmluvě stále zavřeno

    Czech Academy of Sciences Publication Activity Database

    Müllerová, Hana

    2016-01-01

    Roč. 16, č. 2 (2016), s. 8-40 ISSN 1213-5542 Institutional support: RVO:68378122 Keywords : access to justice in environmental matters * Court of Justice of the EU * non-privileged applicants Subject RIV: AG - Legal Sciences