WorldWideScience

Sample records for enno mttus ilme

  1. Kino Iiriksen uusi visuaalinen ilme

    OpenAIRE

    Lumme, Katja

    2011-01-01

    Tämä opinnäytetyö käsittelee uuden visuaalisen ilmeen luomista lahtelaiselle elokuvateatteri Kino Iirikselle. Työn tavoite oli uudistaa ja päivittää elokuvateatterin visuaalinen identiteetti. Työn tuloksena syntyi uusi yritystunnus ja muut sovellukset. Työn tutkimuskysymys on ”Millainen visuaalinen ilme tukisi paremmin elokuvateatteri Kino Iiriksen arvoja, palvelisi paremmin nykyistä käyttäjäryhmää ja houkuttelisi myös uusia asiakkaita?”. Markkinointiviestinnän teorioita käytettiin apuna ...

  2. Close Encounters 2011: Opiskelijafestivaalin visuaalinen ilme

    OpenAIRE

    Kozulya, Maria

    2011-01-01

    Toiminnallisessa opinnäytetyössä suunnitellaan Helsingin Pop & Jazz Konservatorion opiskelijafestivaali Close Encountersin visuaalinen ilme keväälle 2011. Ilme luodaan soveltuvaksi niin verkkoon kuin paperille. Festivaalin visuaalisen ilmeen suunnittelun lopputuotteina on lentolehtiset, julisteet, ohjelmalehti, verkkosivut ja klubilogo. Kirjallisessa osiossa käydään läpi graafiseen suunnitteluun vaikuttavat seikat verk­ko- ja pai­novaatimukset huomioon ottaen. Visuaalisen ilmeen eri osis...

  3. Launeen keskuspuiston visuaalinen ilme ja infografiikka

    OpenAIRE

    Virtanen, Jenni

    2013-01-01

    Opinnäytetyön aiheena on suunnitella Launeen keskuspuistolle visuaalinen ilme ja sitä noudattavat sovellukset. Visuaaliseen ilmeen suunnitteluun kuuluu logon, typografian ja tunnusvärien suunnittelu. Sovelluksissa painotan erityisesti informatiivisia sovelluksia, kuten opastejärjestelmää, aluekarttaa ja infotaulun asettelua. Itse työ on konseptisuunnitelma. Opinnäytetyötäni varten olen tutkinut suomalaisia teema- ja kaupunkipuistoja ja niiden visuaalisia ilmeitä. Painotin tutkimuksessani e...

  4. Enno Toomsalu 30 aastat Chicago Eesti Maja president / Endel Sepp

    Index Scriptorium Estoniae

    Sepp, Endel

    2006-01-01

    1976. aastast Eesti Maja juhtinud Enno on kujundanud selle "väikeseks Eestiks", kus on korraldatud palju kultuuriüritusi. 19. märtsi koosolekul andis ta ameti nooremale, samas valiti ta Chicago Eesti Maja auliikmeks. Akadeemiliselt kuulub ta Korp! Frat. Estica´sse, teda on autasustatud korporatsiooni Kuldmärgiga teenete eest eestlusele ja Valgetähe 4. järgu ordeniga

  5. ILM peeling in nontractional diabetic macular edema: review and metanalysis.

    Science.gov (United States)

    Rinaldi, M; dell'Omo, R; Morescalchi, F; Semeraro, F; Gambicorti, E; Cacciatore, F; Chiosi, F; Costagliola, C

    2017-10-31

    To evaluate the effect of internal limiting membrane (ILM) peeling during vitrectomy for nontractional diabetic macular edema. PUBMED, MEDLINE and CENTRAL were reviewed using the following terms (or combination of terms): diabetic macular edema, nontractional diabetic macular edema, internal limiting membrane peeling, vitrectomy, Müller cells. Randomized and nonrandomized studies were included. The eligible studies compared anatomical and functional outcomes of vitrectomy with or without ILM peeling for tractional and nontractional diabetic macular edema. Postoperative best-corrected visual acuity and central macular thickness were considered, respectively, the primary and secondary outcomes. Meta-analysis on mean differences between vitrectomy with and without ILM peeling was performed using inverse variance method in random effects. Four studies with 672 patients were eligible for analysis. No significant difference was found between postoperative best-corrected visual acuity or best-corrected visual acuity change of ILM peeling group compared with nonpeeling group. There was no significant difference in postoperative central macular thickness and central macular thickness reduction between the two groups. The visual acuity outcomes in patients affected by nontractional diabetic macular edema using pars plana vitrectomy with ILM peeling versus no ILM peeling were not significantly different. A larger prospective and randomized study would be necessary.

  6. Ernst Enno etluskonkursil kõlas saja aasta tagune luule / Krista Kumberg

    Index Scriptorium Estoniae

    Kumberg, Krista, 1959-

    2007-01-01

    Läänemaal toimus maakondlik Ernst Ennole pühendatud etluskonkurss. E. Enno nimelise etluskonkursi 2007 "Saja aasta tagused luuletused" parimad etlejad olid Mike Richard Koch, Janno Allika, Hanna Ring, Karl Poll, Britta Sool, Antero Rea, Jennifer Cohen, Brita Kaljuvee, Eva-Maria Brock, Kaupo Engel, Liisi Räli, Laivi Kovalenko, Merje Viigand, Carmen Freimann, Rauno Punk, Maarja Palmiste

  7. "Absindijoojad" ja "Eesti neiu" graafikute pilgu läbi / Enno Ootsing, Vive Tolli ; intervjueerinud Ellu Maar

    Index Scriptorium Estoniae

    Ootsing, Enno, 1940-

    2007-01-01

    Graafikud Enno Ootsing puugravüüri spetsialistina ja Vive Tolli sügavtrükispetsialistina Eduard Wiiralti töödest, erinevatest graafikatehnikatest ja nende iseärasustest, värvilise kõrg- ja sügavtrüki tegemise tehnilisest poolest ning tõmmisteks sobivatest paberitest

  8. Fast Ss-Ilm a Computationally Efficient Algorithm to Discover Socially Important Locations

    Science.gov (United States)

    Dokuz, A. S.; Celik, M.

    2017-11-01

    Socially important locations are places which are frequently visited by social media users in their social media lifetime. Discovering socially important locations provide several valuable information about user behaviours on social media networking sites. However, discovering socially important locations are challenging due to data volume and dimensions, spatial and temporal calculations, location sparseness in social media datasets, and inefficiency of current algorithms. In the literature, several studies are conducted to discover important locations, however, the proposed approaches do not work in computationally efficient manner. In this study, we propose Fast SS-ILM algorithm by modifying the algorithm of SS-ILM to mine socially important locations efficiently. Experimental results show that proposed Fast SS-ILM algorithm decreases execution time of socially important locations discovery process up to 20 %.

  9. FAST SS-ILM: A COMPUTATIONALLY EFFICIENT ALGORITHM TO DISCOVER SOCIALLY IMPORTANT LOCATIONS

    Directory of Open Access Journals (Sweden)

    A. S. Dokuz

    2017-11-01

    Full Text Available Socially important locations are places which are frequently visited by social media users in their social media lifetime. Discovering socially important locations provide several valuable information about user behaviours on social media networking sites. However, discovering socially important locations are challenging due to data volume and dimensions, spatial and temporal calculations, location sparseness in social media datasets, and inefficiency of current algorithms. In the literature, several studies are conducted to discover important locations, however, the proposed approaches do not work in computationally efficient manner. In this study, we propose Fast SS-ILM algorithm by modifying the algorithm of SS-ILM to mine socially important locations efficiently. Experimental results show that proposed Fast SS-ILM algorithm decreases execution time of socially important locations discovery process up to 20 %.

  10. The Expansion of RPE Atrophy after the Inverted ILM Flap Technique for a Chronic Large Macular Hole

    Directory of Open Access Journals (Sweden)

    Hisanori Imai

    2014-03-01

    Full Text Available Purpose: To report a case of the expansion of submacular retinal pigment epithelium (RPE atrophy after using the inverted internal limiting membrane (ILM flap technique for a persisting, large, stage IV macular hole (MH. Case Report: A 79-year-old woman presented with a chronic large MH that remained open despite pars plana vitrectomy (PPV. The surgery was performed twice for the MH closure 14 years earlier. ILM peeling was not performed during the previous surgeries. The best-corrected visual acuity (BCVA with the Landolt ring chart was 0.08 at her visit. The minimum MH diameter was 1,240 μm. Inverted ILM flap technique with 20% SF6 gas tamponade was performed for the MH closure. For the inverted ILM flap technique, 25-gauge PPV and ILM staining with indocyanine green were used. The ILM was peeled off for 2 disc diameters around the MH, but the ILM was not removed completely. The ILM was then inverted and covered the MH. Results: One month after surgery, the MH was closed, accompanied by glial cell proliferation spreading from the inverted ILM flap (as reported before. On the other hand, the area of the submacular RPE atrophy, which was already observed 1 week after surgery, gradually increased in size. BCVA improved to 0.3 six months after the surgery. Conclusions: The inverted ILM flap technique may be promising even for persisting large MH which were not closed in previous surgeries, but long-term observation is needed because the detailed behavior of the inverted ILM and the Müller cells after surgery is not yet known.

  11. Euroopa Ajalooliste Kalmistute Assotsiatsioon : rahvusvahelised koostööprojektid / Ilme Mäesalu

    Index Scriptorium Estoniae

    Mäesalu, Ilme

    2005-01-01

    ASCE (Assotiation of Significant Cemeteries in Europe) peaeesmärkidest, tegevusest. Muinsuskaitsameti esindaja Ilme Mäesalu on alates liidu asutamisest 2001. a. kuulunud ASCE juhatusse. 2004. a. ilmus Bolognas koguteos "Cemeteries of Europe. A Historical Heritage to Appreciate and Restore", kus leiduvad artiklid Tallinna surnuaedade ja Tartu Raadi kalmistu kohta. 2004. a. toimus Tartus seminar "Ajalooline kalmistu - kujunemine ja tänapäev"

  12. Las jääda ükski mets! / Ilme Loik-Pärnoja

    Index Scriptorium Estoniae

    Loik-Pärnoja, Ilme

    2003-01-01

    Tõrva loodusfestival algas 3. VIII näituste avamisega. Kirikus olid väljas Milvi Torimi akvarellid, Ilme Loigu (Pärnoja) õlimaalid, Luule Luuse haldjapildid, Reet Ohna minivitraažid ja Leonhard Lapini graafika, koolimajas - Laine Vettiku tikandid ja lapitööd, Peeter ja Rein Einasto loodusfotod, Aleksander Tulluse suuremõõdulised maalid. 8. VIII lillestuudio Florist korraldatud lillepeost. Toimus ka palju muusikalisi ülesastumisi

  13. Vitrectomy with internal limiting membrane (ILM) peeling versus vitrectomy with no peeling for idiopathic full-thickness macular hole (FTMH)

    DEFF Research Database (Denmark)

    Spiteri Cornish, Kurt; Lois, Noemi; Scott, Neil

    2013-01-01

    Several observational studies have suggested the potential benefit of internal limiting membrane (ILM) peeling to treat idiopathic full-thickness macular hole (FTMH). However, no strong evidence is available on the potential benefit(s) of this surgical manoeuvre and uncertainty remains among vitr...

  14. Tulemuslikkuse hindamine : efektiivsuse analüüs Käru raamatukogu näitel / Ilme Säde

    Index Scriptorium Estoniae

    Säde, Ilme

    2011-01-01

    Ülevaade Ilme Säde uurimustööst "Raamatukogutöö efektiivsuse analüüs lugejate ja töötajate hinnangute ning kvantitatiivsete tulemusnäitajate abil Käru rahvaraamatukogus aastatel 2005-2010"

  15. Phytoplankton composition of the water and gastrointestinal tract of the mussel Diplodon enno (Ortmann, 1921) from São Francisco river (Bahia, Brazil).

    Science.gov (United States)

    Alves, T; Lima, P; Lima, G M S; Cunha, M C C; Ferreira, S; Domingues, B; Machado, J

    2016-06-01

    The knowledge on diet composition of the freshwater mussel Diplodon enno (Ortmann) would aid in its culture and propagation allowing, this way, the replacement of natural endangered populations in Brazil. Microalgae are the main food source for captive mussels and unionids have displayed an ability to sort algae based on the cellular characteristics prior to ingestion. The main objective of the present work is to analyze the phytoplankton composition of the water from and of the gastrointestinal contents of the mussel D. enno, as an initial step for development of a suitable rearing diet. Therefore, water samples and bivalve specimens were collected from S. Francisco River, city of Paulo Afonso, Bahia, Brazil. The microalgal composition found in water and stomach/gut content samples was very diverse being represented by the following divisions: Cyanophyta, Chlorophyta, Dinophyta and Heterokontophyta (Diatoms). Concerning the relative abundance of microalgae divisions, it is possible to state, for the water and gastrointestinal contents, that Cyanophyta represents 15% and 14%, Chlorophyta 54% in both, Heterokontophyta 31% and 27% and Dinophyta 0% and 5%, respectively. According to the Brazilian CETESB criteria for phytoplankton species classification, 50% of Cyanophyta and 15% of Chlorophyta species observed in the water samples were classified as "very frequent", as were 68% of Heterokontophyta and 33% of Chlorophyta species in the gut/stomach tract samples. Focusing at a species level, although in the water only Coelastrum sp. and Chroococcus sp. were observed in 100% and 75% of the samples, respectively, in the gastrointestinal tract the species Staurastrum sp., Aulacoseira sp., Scenedesmus sp. and Fragilaria crotonensis occurred in 80% to 100% of the samples. The present results showed that D. enno feeds not only on small chlorophytes microalgae, due to their convenient size that facilitates higher feeding rates, but also on large size diatoms, due to a possible

  16. Erilaisen omanlainen : yhteisötaiteellisen projektin prosessin sähköisen julkaisun taitto ja kuvataidenäyttelyn visuaalinen ilme

    OpenAIRE

    Azevedo, Hanna

    2017-01-01

    Opinnäytetyön aihe on sähköisen julkaisun taitto, kuvataidenäyttelyn visuaalinen ilme ja näyttelyyn liittyvien painotuotteiden taitto. Julkaisu kuvaa yhteisötaiteellisen prosessin Erilaisen omanlainen, taiteellisen teeman käsittelyn ja työn etenemisen valmiiksi kokonaiseksi näyttelyksi Art Kaarisiltaan Sanomatalossa 14.6.-3.7.2016. Opinnäytetyölläni pyrin vastaamaan kysymyksiin miten julkaisun graafisella suunnittelulla ja näyttelyn visuaalisella ilmeellä tuodaan esiin yhteisötaiteelline...

  17. Methodology and Characteristics of Zad al-masir fi ‘ilm al-tafsirby AllamaIbn al-Jawzī (Urdu

    Directory of Open Access Journals (Sweden)

    Dr. Muhammad Riaz al Azhari

    2017-01-01

    Full Text Available This article describes the methodology and characteristics of Zad al-masir fi ‘ilm al-tafsir. This is one the finest work of AllamaIbn al-Jawzī, a 6th century prominent Interpreter. Several editions of this Tafsir have been published. However, the edition of dar al-kitab al-‘arbi, Beirut published in four volumes is selected for this study. This exegesis is based on conventional narrations, authentic quotations from the Islamic Scholars and lingual & grammatical discussions. As a witness, causes of verses (asbabal-Nuz┴l,Makki and MadaniSurah’s (chapters, the abrogating and abrogated verses (al-nasikhwal-mans┴kh and Islamic jurisprudence have been discussed in it where needed. The quality of this translation which is admirable is that mostly authentic Ahadith from original sources, and references to well known basic books in relevant discussions have been described. `

  18. Aasta betoonehitis 2002 / Enno Rebane

    Index Scriptorium Estoniae

    Rebane, Enno, 1964-

    2003-01-01

    Betoonehitis 2002 - Tartu vangla, Kalle Rõõmuse Arhitektuuribüroo (projekteerija EstKONSULT, ehitaja AS Skanska EMV). Eriauhinnad: arhitektuurse lahenduse eest - Erki Valdre, Tuvi t. 12 korterelamud Tallinnas; projekteerijale - Eesti Projekt, Linnamäe hüdroelektrijaama taastamine (arhitekt Raine Karp); ehitusmaterjalitootjale - E-Betoonelement, STT katuseelement (Nefab Eesti AS pakenditehas, arhitektuurne lahendus - Tõnis Tarbe Arhitektuuribüroo)

  19. Ehitusmaterjalide toodang mais ja juunis / Enno Rebane

    Index Scriptorium Estoniae

    Rebane, Enno, 1964-

    2005-01-01

    Eesti ettevõtted müüsid statistikaameti andmetel 2005. a. mais tööstustoodangut 7,02 miljardi krooni eest, sealhulgas töötleva tööstuse ettevõtted 6,35 miljardi krooni eest. 2005. a. juunis müüdi tööstustoodangut 6,87 miljardi krooni eest, sealhulgas töötleva tööstuse ettevõtted 6,28 miljardi krooni eest

  20. Hiina linna uued ilmed / Katja Koort

    Index Scriptorium Estoniae

    Koort, Katja

    2007-01-01

    Hiina nüüdiskunsti näitus "Linnailmed / City Expressions" Tallinna Kunstihoones kuni 28. I. Osalevad Guangzhou ja Guangzhouga seotud kunstnikud. Kuraatorid Reet Varblane ja Zuo Zhengyao, kujundaja Rosita Raud. Pikemalt Feng Fengi, Yu Xudongi, Zuo Zhengyao, Weng Feni, Li Bangyao ja Hu Xiangqiani töödest

  1. Hea uus Eesti ilm / Tanel Veenre

    Index Scriptorium Estoniae

    Veenre, Tanel, 1977-

    2008-01-01

    Eesti kultuurist, uuest rahvuslikust tõusust muusikas (folgifestivalid, folk-metal muusika, öölaulupeod), moes (rahvariiete buum, Aldo Järvsoo kollektsioon Folkcouture, noorte moekunstnike tööd Supernooval), filmis ja teatris (Taarka, Anton Hansen Tammsaare suvelavastused, Pärimusteater Loomine), arhitektuuris, kirjanduses ja kokakunstis

  2. Ernst Enno 121 : [Ernst Enno nimelise kirjandusliku omaloominguvõistluse 1996. aasta paremad luuletused

    Index Scriptorium Estoniae

    1996-01-01

    Janek Nee (Haapsalu Wiedemanni gümnaasiumi 11. kl.). Teed lõpmatusse; Liina Krips (Haapsalu gümnaasiumi 12. kl.). Inimene, 'Olin arvanud, et minust hoolitakse...'; Loola Hütt (Haapsalu sanatoorse internaatkooli 13. kl.). 'Mäletad kui hele oli kuu..., 'Jälle ei jõa kuu...', 'Suveöö sumedates silmapilkudes...'; Evelin Lillepuu (Taebla gümnaasiumi 9. kl.). Tuul; Anne Roovere (Kullamaa keskk. 8. kl.). See on koht; Martin Kaasik (Haapsalu Wiedemanni gümnaasiumi 7. kl.). Vembumehed; Külli Kivi (Haapsalu Wiedemanni gümnaasiumi 9. kl.). Vaikus

  3. Palve : [luuletused] / Ernst Enno ; [Impressioonid]: Viiu Härm

    Index Scriptorium Estoniae

    Enno, Ernst, 1875-1934

    2004-01-01

    Sisu: Palve ; Ma kuulan ; Imeline helin ; Nad langesid tasa, tasa ; Nii tasa mängisid lained ; Mu õnn ; iks ruttad, väsinud rändaja? ; Valge öö ; Kui ärkab ; Kui virmalised vehklevad ; Vii ära ; Väike paju ; Kui sõuaks igavikku ; Ei me suutnud ; Sügisel ; Su silmis ; Ja jälle sõuab ; Jõulurõõm ; Igatseja kodu ; Hääd ööd! ; Õhtu Pühajärvel ; Peipsi kaldal ; Õhtu ; Kodune ilu! ; Rannal ; Ma tulen hilja ; Märgitud ; Nõmmeallik, Õhtule! ; Kurbus ; Vesiroos ; Kojuigatsus ; Õhtu kodutalus ; Kevade õhtul ; Mu tuba on väike ; Kodukask ; Kallimeelsed ; Jutluse ajal ; Kauge kõlin ; Suvel ; Hall laul ; Igatsus ; Põud ; Ta tuli ; Suvi ; Hõõgamine ; Rändaja õhtulaul ; Tuul alulis ; Võiks otsast alata ; Kolm eite ; Nõmme pääl ; Nõmmeigatsus ; Vanaisa surm ; Karjamaal, Kas sa iial ei küsi ; Imelikku rada pikka! ; Üks lilleke ; Sütti, sütti! ; Noore suve muinasjutt ; Su omasem silmapilk ; Igatsus; Kullerkupp ; Öö valge on õnn ; Tartu valgel ööl ; Vari ; Hääd jällenägemist ; Ühele sõbrale ; Nii läbisegi jooned ; Hõbemeelne luul ; Kui suri lill ; Sind jumalaga jätsin sääl ; Ja eluvalgus, see on nende and ; Ja saadus hing ; Sügise ; Kodu imelisem töö ; Ja pisarad sul kipuvad silma ; Nad läevad pikas reas ; Nad ei vaata tagasi! ; Kadunud kodu! ; Sa oled inime ; Meil kõigil ühine on pulmapidu ees ; Ja jahtund süda jäta ilmale ; Siis vaikivad kõik mõtted ; Nii vaikseks kõik on jäänud ; Siin-sääl kui katkend viisid ; Nii, nii see küll ikka oli ; Ei ole tühi jutt ; Oli viisiks koju tulla ; Tuba, väike tuba ; Sa ära küsi ; Kuulmata kuskil kumiseb kodu ; Mere ääres tuba vaikne ; Ei ükski neist armasta mind ; Igatsus ; Lumesõda ; Tuul käib tühjal rannal ringi ; Üks rohutirts läks kõndima ; Hilissuvi ; Tähte väli vaatas vette ; Valge unustus

  4. Logistika roll innovatsiooni juhtimises / Enno Lend, Valev Reinhold

    Index Scriptorium Estoniae

    Lend, Enno

    2004-01-01

    Nii logistika kui innovatsioon on suunatud konkurentsieelise saavutamisele: kui innovatsiooni probleemiks on, missuguseid väärtuslikke uuendusi inimestele nende vajaduste rahuldamiseks luua/pakkuda, siis logistikas otsitakse vastust küsimusele, kuidas selleks võimalikult efektiivsemalt ressursse kasutada. Skeemid

  5. Aasta Betoonehitis 2003 - elamu mere kaldal / Enno Rebane

    Index Scriptorium Estoniae

    Rebane, Enno, 1964-

    2004-01-01

    2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

  6. Viru tunnel saab uue ilme urbanistliku grafiti abil / Ilmar Kahro

    Index Scriptorium Estoniae

    Kahro, Ilmar

    2011-01-01

    MTÜ Linnalabor koostöös Tallinn 2011 SA-ga viis läbi Tallinnas Gonsiori ja Laikmaa tänava ristmiku all paikneva Viru tunneli kujunduskonkursi "Viru tunnel kunstigaleriiks". EKA skulptuuri eriala tudengi Eldar Jakubovi võidutööst "Avame linna"

  7. ame. In anzini, ilm and ed from etrieved n, 20

    African Journals Online (AJOL)

    Precious

    person sufficiently enough, a series of rituals and dances are performed and one of such rituals is the .... music and dance, conscientization, sensitization, ritual displays, and above all, to bring in spiritual messages from ..... and Arab civilizations are secondary to the Igala culture. The Igala knowledge of nature, supernatural ...

  8. President sai hindeks 6,8, Meri võimalus 4,2 / interv. Enno Tammer

    Index Scriptorium Estoniae

    1996-01-01

    Intervjuu Riigikogu liikmetega presidendi senisest tööst ja L. Meri kandidatuuri võimalustest presidendivalimistel. Küsimustele vastavad R. Üksvärav, S. Oviir, A. Tarand, T. Jürgenson, A. Varik, S. Ivanov, A. Veidemann, H. Kranich ja M. Siimann

  9. Müüdid ja faktid põlevkivi kaevandamise keskkonnakahjulikkusest / Enno Reinsalu

    Index Scriptorium Estoniae

    Reinsalu, Enno, 1936-

    2006-01-01

    Ilmunud ka: Severnoje Poberezhje 6. jaan. lk. 2, Mente et Manu 18. jaan. lk. 3. TTÜ emeriitprofessori hinnangul võib organiseeritud vastuseis meie põlevkivitööstusele lähendada Eestit gaasi- ja naftasõltlase seisusele

  10. Valitsejad püsinud aasta otsa pukis / interv. Enno Tammer

    Index Scriptorium Estoniae

    2000-01-01

    Küsimustele, mis puudutavad valitsuse saavutusi ja probleeme, vastavad valitsuse liikmed M. Laar, J. Luik, T. Loodus, T. Lukas, T. Jürgenson, S. Kallas, M. Rask, S. Kivi, H. Kranich, T. Asmer, T.-H. Ilves, E. Nestor, M. Pärnoja, I. Padar, K. Saks

  11. Kuidas sertifitseerida kaupa, mis läheb Venemaale / Enno Aloe

    Index Scriptorium Estoniae

    Aloe, Enno

    1995-01-01

    Kommentaarid kohustuslikule sertifitseerimisele kuuluva Venemaale sisseveetava kauba sertifitseerimise kohta. Kinnitatud 15. sep. 1994. a., jõustunud 1. okt. 1994. a.; Lisa 1: Kohustuslikult sertifitseerimisele kuuluvate kaupade ja teenuste nimistu; Lisa 3: Rahvusvahelised sertifitseerimissüsteemid, millega Venemaa on ühinenud. Tõlkeallikas: Pravo i Ekonomika, 1994, Nr. 35

  12. Sõit-sõit läbi salu : [luuletused] / Ernst Enno

    Index Scriptorium Estoniae

    Enno, Ernst, 1875-1934

    2000-01-01

    Sisu: Sõit-sõit läbi salu ; Juss oli väike peremes ; Juss päikesele ; Õhtulaul ; Tipa kooliteel ; Patsu, patsu, kooki ; Tipa-tapa hällilaul ; Üks rohutirts läks kõndima ; Laps ja tuul ; Puder ; Sügisel ; Tuul käib tühjal rannal ringi ; Sügisel ; Tikk, takk ; Hällilaul ; Koju ; Kus mu väike linnukene ; Kured tulevad ; Notsu laul ; Tibukese unenägu ; Marjule ; Emakene ; Aha ai, aha pai ; Väike rohutirts ; Sula ; Kaks jänest ; Uisutajad

  13. Osobnjak na beregu morja - lutshsheje betonnoje strojenije 2003 goda / Enno Rebane

    Index Scriptorium Estoniae

    Rebane, Enno, 1964-

    2004-01-01

    2003. a. parim betoonehitis - arhitekt Emil Urbeli kavandatud eramu (projekteerija TA Konsult OÜ, betoonitööde teostaja Mapri Projekt OÜ). Eriauhinna arhitektuurse lahenduse eest sai Siiri Vallneri, Hanno Grossschmidti ja Tomomi Hayashi kavandatud Lasnamäe spordihoone (projekteerija TA Konsult OÜ, ehitasid Eesti Ehitus OÜ, AS E-Betoonelement - ka betoonisegu tarnija) ja betoonitehnoloogia eest AS E-Betoonelement Ekseko seafarmi sõnnikuhoidla eest Viljandimaal. IV betoonipäevast

  14. Saarte juurdepääsetavuse ja majandusarengu seosed / Enno Lend

    Index Scriptorium Estoniae

    Lend, Enno

    2005-01-01

    Lisaks transpordiühenduse nüüdisajastamisele tuleb Saaremaa ja Hiiumaa ettevõtete konkurentsivõime säilitamiseks ning tõstmiseks autori arvates tegeleda ka tehnoloogia- ja personaliinnovatsiooniga. Kaart. Skeemid. Diagrammid. Tabelid

  15. Heitlik ilm süvendab luu- ja liigesevalu / Anneli Aasmäe

    Index Scriptorium Estoniae

    Aasmäe, Anneli, 1973-

    2008-01-01

    Tartu Ülikooli Kliinikumi sisekliiniku reumatoloogia dotsendi Riina Kallikormi, Kuressaare erakliiniku Luukas reumatoloogi Reinhold Birkenfeldti ja Ida-Tallinna Keskhaigla reumatoloogi Tõnu Peetsi kinnitusel on kõik krooniliste reumaatiliste haigustega inimesed ilmatundlikud

  16. ILM AL LUGHAH AL IJTIMAI WA TALIM AL LUGHAH AL ARABIYYAH LI AL NATHIQINA BI GHAIRIHA

    Directory of Open Access Journals (Sweden)

    Ahmad Ubaedillah Fathuddin

    2017-03-01

    Full Text Available Language learning cannot work without integrating other fields of knowledge such as psychology, anthropology, sociolinguistics, etc. Sociolinguistics is a branch of linguistics which discusses about language due to social factors. It has an important role in language learning especially in making it easily understandable for the language learners by understanding the language use of the native speakers. The contribution of sociolinguistics in Arabic language learning for foreign language learners can be seen from the relationship between language and social environment. In this case, it does not only learn about the elements or internal systems of Arabic language such as phonology, syntax, and morphology, but also the social context such as speech community, social class, language use and culture. It means sociolinguistics gives information about the definition and use of Arabic language based on the social context.

  17. Tunnustame tõenduspõhise õendusabi edendajaid / Ester Öpik, Ilme Aro

    Index Scriptorium Estoniae

    Öpik, Ester

    2014-01-01

    Tunnustati meditsiiniõdesid Tiina Freimanni, Reet Urbanit, Marika Asbergi, Tiina Tõemetsa, Kersti Viitkarit ja Ireen Bruusi Eesti Õdede Liidu poolt 2011. aastani kaitstud õendusteaduslike uurimistööde eest

  18. Iraagist naasnud Leo Kunnas : sõja nimi on sõda / Leo Kunnas ; interv. Enno Tammer

    Index Scriptorium Estoniae

    Kunnas, Leo, 1967-

    2005-01-01

    Iraagist naasnud kolonelleitnant vastab küsimustele, mis puudutavad Iraagi-missiooni ja selle pikendamist, Eesti kaitseväelaste osalemist missioonil ning Eesti riigipiiri rikkumisi Vene sõjalennukite poolt. Lisa: Kiirarvamus

  19. Water Seri raskused partnerite kanda. Tõehetk sel nädalal / Alyona Stadnik ; kommenteerinud Tõnis Kurrik, Enno Heringson

    Index Scriptorium Estoniae

    Stadnik, Alyona

    2011-01-01

    Sindi Vesi muutis kuu pärast riigihanke väljakuulutamist linna vee- ja kanalisatsioonitorustike hanke tingimust, täitmistagatise garantii tuleb esitada 28 päeva jooksul pärast lepingule allakirjutamist. Töid alustanud Water Ser Lääne-Eesti pole siiani garantiid esitanud. Vt. ka: Stadnik, Alyona. Water Ser esitas Sindi projektile garantiipaberi. Äripäev 26. mai, lk. 9

  20. Peaminister : Euroopa Liiduga ühinemise otsustab rahvas / Mart Laar ; interv. Dirk Koch, tõlk. Margus Enno

    Index Scriptorium Estoniae

    Laar, Mart, 1960-

    2000-01-01

    Ilmunud ka: Järva Teataja 17. okt. lk. 2. Eesti peaminister vastab Der Spiegeli küsimustele, mis puudutavad Eesti ühinemisläbirääkimisi EL-iga, Eesti rahva osast ühinemisotsuse langetamisel, Eesti soovist saada NATO liikmeks. Avaldatud lühendatult. Autor: Isamaaliit

  1. Kui kõik on kõigile võlgu / Liivi Tamm ; kommenteerinud Indrek Peterson, Enno Rebane, Jaan Luts

    Index Scriptorium Estoniae

    Tamm, Liivi, 1978-

    2010-01-01

    Ehituses on peatöövõtjaid, kes on võlgu alltöövõtjatele või tarnijatele, maksmata jäetakse nii meelega kui ka rahapuudusest. Võlgu olemise probleem on terav ka ehitusmaterjalitootmise sektoris

  2. Kaks mõrva ühes mesilasperes ehk laibarida ei tule / Lauri Tabur ; interv. Enno Tammer

    Index Scriptorium Estoniae

    Tabur, Lauri, 1974-

    2005-01-01

    Keskkriminaalpolitsei ülem vastab küsimustele, mis puudutavad Tallinna koolitüdruku Veronika Dari, eestikeelse allilma väidetava liidri Kalev Kure ning ärimees Kauri Koppeli mõrvu Tallinnas. Lisa: Kiirarvamus

  3. Abikaasade varalised õigused ja kohustused perekonnaõiguses : [bakalaureusetöö] / Mairis Kungla ; Akadeemia Nord, õigusteaduskond ; juhendaja: Enno Oidermaa

    Index Scriptorium Estoniae

    Kungla, Mairis

    2000-01-01

    Ajalooline ülevaade abikaasade varalistest õigustest ja kohustustest Rooma õiguses, Balti Eraseaduses, ENSV abielu- ja perekonnakoodeksis, kehtivas õiguses. Abieluvaraleping abikaasade varaliste õiguste ja kohustuste alusena

  4. Isast põlvnemise õiguslik regulatsioon Eesti Vabariigis : [bakalaureusetöö] / Maris Kask ; Akadeemia Nord, õigusteaduskond ; juhendaja: Enno Oidermaa

    Index Scriptorium Estoniae

    Kask, Maris

    2006-01-01

    Perekonnaõiguse arengust ning põlvnemise õiguslikust regulatsiooniste Eesti Vabariigi territooriumil, põlvnemise õiguslik regulatsioon perekonnaseaduse järgi, õiguslikke probleeme isast põlvnemise regulatsioonis

  5. Coca-Cola : kasumi languses on süüdi Põhja-Euroopa kehv ilm / Raivo Sormunen

    Index Scriptorium Estoniae

    Sormunen, Raivo, 1976-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 29. sept. lk. 6. Karastusjookide tootja Coca-Cola andis kasumihoiatuse. Ettevõtte majandustulemuste languse põhjustest. Diagramm: Coca-Cola aktsia aasta madalaimal tasemel. Vt. samas: Annika Matson. Coca-Cola jooksev kvartal Eestis saladus

  6. Tatawwur 'Ilm al-Ijtima fi Turkiya al-Haditha: Qissat al-Bahth an Huwiyya Jadida

    OpenAIRE

    Şentürk, Recep

    1989-01-01

    صار علم الاجتماع في تركيا اليوم جزءاً لا يتجزأ من الحياة الاجتماعية ، إذ إنه أدى وما زال يؤدي دوراً كبيراً في تحديث و( تغريب ) المجتمع .ويبقى السؤال إلى متى ستستمر مشكلة البحث عن الهوية في المجتمع التركي وعلم الاجتماع التركي ؟ Türkiye'de sosyoloji sosyal hayatın ayrılmaz bir parçası haline gelmiştir ve toplumun modernizasyonu ve değişmesinde büyük rol oynamaktadır. Ancak, Türk toplumunda kimlik arayışı devam etmektedir....

  7. Ilm al Miqat fi al Hadaratil al 'Arabiyyah wa al Islamiyyah wa Dauruhu fi al Mujtama' al Islami

    Directory of Open Access Journals (Sweden)

    Arwin Juli Rakhmadi Butar-Butar

    2015-02-01

    Full Text Available تعتبر الحضارة الإسلامية العديد من العلوم الطبيعة منها العلوم الفلكية التي تدرس الأجرام السماوية.¬ إن مكانة علم¬ الفلك في العصور¬ الوسطى تتجه في الأساس إلى خدمة العبادة في الإسلام، لاسيما الصلاة والصوم. فمن أجل ذلك نشأ العديد من الفلكيين المسلمين بحثوا في هذا المجال واعترفوا بالموقت. شغل معظم الفلكيّين في هذا العصر، خاصة العصر المملوكي، وظيفة موقّت وهو فلكي محترف ملحق بأحد المساجد بالأجرة من السلطان، وكان مهمته تحديد أوقات الصلاة والصوم. ففي العصور الوسطى يعترف هذا الشغل بمؤسسة الموقت، وهي المجتمع تدرس الأجرام السماوية لخدمة العبادة.

  8. Tamula rannaala ideevõistluse võitis lustakas nägemus

    Index Scriptorium Estoniae

    2008-01-01

    Võistlusele esitatud tööde näitus Võrumaa Muuseumis. Preemiasaajate nimed. Võidutöö nimetusega "Lust" autor on K. Enno Arhitektuuribüroo koosseisus Kaie Enno, Leles Luhse, Maria Zeleznova ja Rein Ailt

  9. The Professorial Chair (kursī ‘ilmī or kursī li-l-wa‘ẓ wa-l-irshād in Morocco

    Directory of Open Access Journals (Sweden)

    Erzini, Nadia

    2013-06-01

    Full Text Available Moroccan congregational mosques are equipped with a minbar (pulpit which is used for the Friday sermon. Many mosques in Morocco are also equipped with one or more smaller chairs, which differ in their form and function from the minbar. These chairs are used by professors to give regular lectures to students of traditional education, and by scholars to give occasional lectures to the general public. This tradition of the professorial chair was probably introduced to Morocco from the Middle East in the thirteenth century. Most of the existing chairs in Morocco seem to date from the nineteenth and twentieth centuries, and they continue to be made and used today. The chairs always have two steps, a seat, a backrest and armrests. This form probably evokes the original minbar of the Prophet in Medina, which had two steps and a seat, and this is one of many aspects of the conservatism and se parate evolution of Moroccan Malikism.Las mezquitas congregacionales en Marruecos suelen tener un almimbar (p?lpito que se utiliza durante el sermón de los viernes. Muchas mezquitas de Marruecos cuentan también con una o más sillas, diferenciadas del almimbar en su forma y su función ya que son utilizadas por los profesores para ensenar a los estudiantes de la educación tradicional, y por eruditos que dan conferencias ocasionales al p?blico en general. Esta tradición de cátedras se introduce probablemente en Marruecos desde Próximo Oriente en el siglo XIII. La mayoría de las cátedras existentes parecen datar de los siglos XIX y XX, manteniéndose hasta nuestros días la fabricación y utilización de estas sillas. Las cátedras siempre tienen dos peldanos, un asiento, un respaldo y apoyabrazos. La forma de las sillas parece evocar el almimbar original del Profeta en Medina, tradición que se muestra como uno de los muchos aspectos del conservadurismo y de la evolución distinta del Malikismo marroquí.

  10. Analysis and chemometry of heavy metal concentrations in the Saale, Ilm and Unstrut as a basis for assessing the pollutant level and the prospects for success of sanitation measures. Final report; Analyse und chemometrische Bewertung von Schwermetallgehalten der Saale, Ilm und Unstrut als Bestandsaufnahme und zur Abschaetzung der Auswirkungen von Sanierungsmassnahmen. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Einax, J.W.; Truckenbrodt, D.; Kampe, O.

    1997-09-01

    Since the mid-1980`s, heavy metal characterisation was carried out on sediments of selected sections of the river Saale and methodical work was done on the analysis of flowing water at the Friedrich Schiller University at Jena. However, there was no comprehensive and current information about the state of contamination along the whole course of the river before. The most important aim was therefore the first and current stocktaking of this extent of contamination of the water, sediment and suspended matter of the Saale. The basis of these considerations was formed by about 15,000 determined features in water samples and more than 1,000 examinations of suspended matter and 4,600 examinations of sediment. In the characterisation of contamination of flowing watercourses, it was generally usual to evaluate the change of individual features according to geographic or time aspects. The application of methods of multi-variate statistics makes it possible to identify anthropogenic and geogenic sources and to discover latent connections. A comprehensive evaluation of the actual contamination situation is possible in this way. (orig./SR) [Deutsch] Seit Mitte der achtziger Jahre werden an der Friedrich-Schiller-Universitaet Jena Schwermetallcharakterisierungen an Sedimenten ausgewaehlter Flussabschnitte der Saale sowie methodische Arbeiten zur Fliessgewaesseranalytik durchgefuehrt. Umfassende und aktuelle Informationen ueber den Belastungszustand entlang des gesamten Flussablaufes gab es jedoch bisher nicht. Wichtigstes Ziel war deshalb eine in diesem Umfang erstmalige und aktuelle Bestandsaufnahme zur Belastung von Wasser, Sediment und Schwebstoffe der Saale. Die Grundlage dieser Betrachtungen bilden ca. 15.000 bestimmte Merkmale in Wasserproben und mehr als 1.000 Schwebstoff- und 4.600 Sedimentuntersuchungen. Bei der Belastungscharakterisierung von Fliessgewaessern ist es derzeit allgemein ueblich, die Aenderung einzelner Merkmale nach geographischen oder zeitlichen Aspekten zu bewerten. Die Anwendung von Methoden der multivariaten Statistik ermoeglicht die Identifizierung anthropogener und geogener Quellen und die Aufdeckung latenter Zusammenhaenge. Damit ist eine umfassende Bewertung der tatsaechlichen Belastungssituation moeglich. (orig./SR)

  11. Tamula rannaala planeering = Competition of spatial planning of the Tamula lakeside area, Võru / Dace Kalvane

    Index Scriptorium Estoniae

    Kalvane, Dace

    2008-01-01

    Žürii liige Võru Tamula järve rannaala mahulise planeeringu rahvusvahelisest ideekonkursist, auhinnatud töödest. Võidutöö "Lust" autorid on Kaie Enno, Leles Luhse, Maria Zeleznova ja Rein Ailt (Kaie Enno Arhitektuuribüroo)

  12. Äriühingud : nende asutamise õiguslik regulatsioon : ajaloolis-võrdlev analüüs (Saksa, Soome ja Euroopa Liit) : [bakalaureusetöö] / Kaire Reispass ; Akadeemia Nord, õigusteaduskond ; juhendaja: Enno Oidermaa

    Index Scriptorium Estoniae

    Reispass, Kaire

    1999-01-01

    Äriühingute olemus ja asutamise alused kehtivas seadustikus, Eesti ettevõtlust reguleeriva õigusloome ajalooline ja võrdlev ülevaade, võrdlev ülevaade Saksa, Soome ja Euroopa Liidu äriühinguõigusest

  13. Arnold Rüütel: meie küla käis käest kätte / Arnold Rüütel ; intervjueerinud Enno Tammer

    Index Scriptorium Estoniae

    Rüütel, Arnold, 1928-

    2005-01-01

    President Arnold Rüütel Teise maailmasõjaga seotud mälestustest, Molotov-Ribbentropi paktist, Moskvas võidupüha tähistamisel mitteosalemise põhjustest ja 2006. a. presidendivalimistel osalemisest

  14. Punta Sayısının Örme Kumaşlarda Eğilme Dayanımı Üzerindeki Etkilerinin Araştırılması

    OpenAIRE

    ÖZKAN, İlkan; BAYKAL, Pınar Duru

    2013-01-01

    In this study, it is aimed to investigate the effects of filament yarn’s number of nips on bending rigidity of knitted fabric which is made of that yarn. For this purpose, polyester POY (Partially Oriented Yarn) filaments with 283 dtex linear density and 68 filaments in cross section were used as raw material. POY bobbins were intermingled at different speed and pressure levels thus yarns having five different numbers of nips were produced. Single jersey knitted fabrics were produced using th...

  15. Sündinud kunstnikuks - kahe Eestis kasvanud juudi lugu / Rein Veidemann

    Index Scriptorium Estoniae

    Veidemann, Rein, 1946-

    2009-01-01

    Arvustus: Tali, Piret. Eino Baskin. Naer läbi pisarate / kirja pannud Piret Tali. [Tallinn] : Fookus Meedia, [2009] ; Tammer, Enno. Simon Levin : sündinud advokaadiks. [Tallinn] : Tammerraamat, 2009

  16. Rae vald ja Jüri elanikud sõdivad tehnopargi ohtliku tehase vastu / Mari Kodres

    Index Scriptorium Estoniae

    Kodres, Mari

    2008-01-01

    Ettevõte Stainless Surface Technology OÜ soovib rajada Jüri tehnoparki metallide hapetega töötlemise tehase. Rae valla ehitusameti juhataja Enno Harmipaiga hinnangul on probleem tehase ja elumajade ühine kanalisatsioon

  17. Linn ostis 135 000 krooni eest kunsti

    Index Scriptorium Estoniae

    2000-01-01

    Tallinna linnavalitsus ostis Tiit Pääsukese "Osaliselt varjatud IV, V, VI" (60000 kr.), Sirje Runge "Vaikus III" (25000 kr.), Jüri Arraku "Purunenud kuju II" (30000 kr.), Enno Halleku "Objekt" (20000 kr.)

  18. Need sinihallid veised... : Marie Under ja Villem Ridala / Ruth Mirov

    Index Scriptorium Estoniae

    Mirov, Ruth, 1928-

    2008-01-01

    Vaadeldakse kahte ühest ja samast muistendist - merest tõusnud lehmakarjast - inspireeritud ballaadi: Marie Underi "Merilehmi" (ilm. kogus "Õnnevarjutus", 1929) ja Villem Ridala "Sinist karja" (ilm. kogus "Sinine kari", 1930)

  19. Effect of Dystrophin Deficiency on Selected Intrinsic Laryngeal Muscles of the "mdx" Mouse

    Science.gov (United States)

    Fry, Lisa T.; Stemple, Joseph C.; Andreatta, Richard D.; Harrison, Anne L.; Andrade, Francisco H.

    2010-01-01

    Background: Intrinsic laryngeal muscles (ILM) show biological differences from the broader class of skeletal muscles. Yet most research regarding ILM specialization has been completed on a few muscles, most notably the thyroarytenoid and posterior cricoarytenoid. Little information exists regarding the biology of other ILM. Early evidence suggests…

  20. Parametric resonance of intrinsic localized modes in coupled cantilever arrays

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, Masayuki, E-mail: kimura.masayuki.8c@kyoto-u.ac.jp [Department of Electrical Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan); Matsushita, Yasuo [Advanced Mathematical Institute, Osaka City University, 3-3-138 Sughimoto, Sumiyoshi-ku, Osaka 558-8585 (Japan); Hikihara, Takashi [Department of Electrical Engineering, Kyoto University, Katsura, Nishikyo-ku, Kyoto 615-8510 (Japan)

    2016-08-19

    In this study, the parametric resonances of pinned intrinsic localized modes (ILMs) were investigated by computing the unstable regions in parameter space consisting of parametric excitation amplitude and frequency. In the unstable regions, the pinned ILMs were observed to lose stability and begin to fluctuate. A nonlinear Klein–Gordon, Fermi–Pasta–Ulam-like, and mixed lattices were investigated. The pinned ILMs, particularly in the mixed lattice, were destabilized by parametric resonances, which were determined by comparing the shapes of the unstable regions with those in the Mathieu differential equation. In addition, traveling ILMs could be generated by parametric excitation. - Highlights: • Destabilization of intrinsic localized modes (ILMs) by parametric excitation is investigated for FPU, NKG, and mixed lattices. • Frequency and amplitude of parametric excitation is determined based on characteristic multipliers of ILMs. • Unstable regions for the mixed lattice case show very similar shape to those of the Mathieu equation. • ILMs become unstable by causing parametric resonance.

  1. Pores of the inner limiting membrane in flat-mounted surgical specimens.

    Science.gov (United States)

    Gandorfer, Arnd; Schumann, Ricarda; Scheler, Renate; Haritoglou, Christos; Kampik, Anselm

    2011-05-01

    To demonstrate the incidence of pores in the inner limiting membrane (ILM) in flat-mounted ILM specimens and to show the immunocytochemical properties of cellular proliferation associated with them. One hundred and twelve ILM specimens from patients with idiopathic macular holes were flat mounted and screened for pores. The ILM was assessed by phase-contrast and interference microscopy. Various antibodies were used against glial cells, hyalocytes, and retinal pigment epithelial cells. In total, only three pores were found. They were characterized by a full-thickness defect of the ILM with irregular borders and cellular proliferation on the ILM. Glial cells were seen in direct association with the ILM pore. Glial cell and hyalocyte markers were the main immunologic features observed. Inner limiting membrane pores are a rare finding. Glial cells are likely to cross the ILM through these pores on their way from the retina to the vitreoretinal border. Given the frequency of cellular proliferation and the rare finding of ILM pores, other pathways have to be considered in playing the leading role in epiretinal proliferation. They might include migration of cells through ILM thinning along retinal vessels and proliferation of vitreous cortex hyalocytes at the vitreoretinal border.

  2. Oceanographic and surface meteorological data collected from station ilm2 by Coastal Ocean Research and Monitoring Program (CORMP) and assembled by Southeast Coastal Ocean Observing Regional Association (SECOORA) in the North Atlantic Ocean from 2014-02-13 to 2016-04-11 (NODC Accession 0118738)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0118738 contains oceanographic and surface meteorological data in netCDF formatted files, which follow the Climate and Forecast metadata convention...

  3. Oceanographic and surface meteorological data collected from station ilm3 by Coastal Ocean Research and Monitoring Program (CORMP) and assembled by Southeast Coastal Ocean Observing Regional Association (SECOORA) in the North Atlantic Ocean from 2014-02-13 to 2016-02-01 (NODC Accession 0118742)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Accession 0118742 contains oceanographic and surface meteorological data in netCDF formatted files, which follow the Climate and Forecast metadata convention (CF)...

  4. Residual cellular proliferation on the internal limiting membrane in macular pucker surgery.

    Science.gov (United States)

    Gandorfer, Arnd; Haritoglou, Christos; Scheler, Renate; Schumann, Ricarda; Zhao, Fei; Kampik, Anselm

    2012-03-01

    To provide pathology data on the completeness of epiretinal membrane (ERM) removal with and without internal limiting membrane (ILM) peeling. Twenty-two patients with idiopathic ERM formation underwent vitrectomy with ERM removal and subsequent staining of the vitreomacular interface with brilliant blue. If the ILM was still present after ERM removal, it was peeled off. Both ERM and ILM specimens were harvested in different containers and prepared for flat-mount phase-contrast and interference microscopy, immunocytochemistry, and transmission electron microscopy. In 14 patients (64%), the ILM was still present at the macula after ERM removal. On average, 20% (range, 2-51%) of the total cell count was left behind at the ILM if the ERM was removed only. There were mainly glial cells on the ILM, and few hyalocytes. In nine eyes, the cells were forming cell clusters. In 8 patients (36%), both ERM and ILM were removed together. Electron microscopy showed cellular proliferation directly attached to the ILM in these eyes, whereas in the sequentially peeled group, there was collagen interposed between the ERM and the ILM. Surgical ERM removal resulted in splitting of the vitreous cortex in these eyes, leaving the ILM with residual cells behind. Simple ERM removal results in sufficient separation of fibrocellular tissue in one third of cases, only. In 2 of 3 patients with idiopathic ERM, the vitreous cortex splits when the ERM is removed, leaving an average of 20% of the total cell count behind on the ILM. As these cells are capable of proliferation and causing ERM recurrence, staining of the ILM with subsequent removal seems beneficial in macular pucker surgery.

  5. INVERTED INTERNAL LIMITING MEMBRANE FLAP TECHNIQUE FOR MACULAR HOLE SURGERY WITHOUT EXTRA MANIPULATION OF THE FLAP.

    Science.gov (United States)

    Casini, Giamberto; Mura, Marco; Figus, Michele; Loiudice, Pasquale; Peiretti, Enrico; De Cillà, Stefano; Fuentes, Taiusha; Nasini, Francesco

    2017-11-01

    To determine whether surgical manipulation steps of the internal limiting membrane (ILM) flap, such as ILM trimmed, ILM tuck inside the hole, ILM massage, are mandatory to obtain satisfactory outcomes for the repair of large stage IV idiopathic macular hole using the inverted ILM flap technique. In this interventional comparative prospective single-masked study, 81 eyes were randomized into 2 treatments groups. In Group 1 (41 eyes), the classic inverted ILM flap technique was performed. In Group 2 (40 eyes), a modified procedure was used: after ILM peeling, no extra flap manipulation was performed. The macular hole was covered by the inverted ILM flap because of the air pressure at the time of the fluid-air exchange. At 12 months, macular hole closure was observed in 40 eyes (97.6%) in Group 1 and in 39 eyes in Group 2 (97.5%). U-shape closure rate, ellipsoid zone defects, and external limiting membrane defects were similar in both groups. The results indicate no statistical difference in anatomical and functional success between both groups. The macular hole closure rate, improved visual acuity, and no extra complications indicate noninferiority of the modified inverted ILM technique. Internal limiting membrane finishing, tucking, and massage may not be required to obtain surgical success.

  6. Histopathologic and Electron Microscopic Features of Internal Limiting Membranes in Maculopathies of Various Etiologies

    Directory of Open Access Journals (Sweden)

    Mozhgan Rezaei Kanavi

    2014-01-01

    Full Text Available Purpose: To report micro- and ultrastructural features of internal limiting membranes (ILMs in various maculopathies and to evaluate the effects of indocyanine green (ICG and triamcinolone acetonide (TA on epiretinal proliferations associated with ILM and on retinal cleavage plane. Methods: ILMs from various maculopathies were evaluated regarding presence or absence of membrane-associated cells, type of cells and ILM thickness based on routine histopathology, immunohistochemistry and transmission electron microscopy (TEM. Results: Thirty ILM specimens were enrolled; 25 of which were evaluated by histopathology and immunohistochemistry and 5 by TEM. ICG only had been used in 17 specimens, TA in 4, and both agents in one specimen. The majority of specimens were immunoreactive for glial fibrillary acidic protein and neuron specific enolase. No significant difference in specimen cellularity and alteration of cleavage plane was noted between ICG-stained and non-ICG-stained ILMs or between TA-assisted and non-TAassisted ones. Excluding central retinal vein occlusion (CRVO cases, acellularity was not observed in any of ILMs from diabetic macular edema (DME, cystoid macular edema (CME, and traumatic macular hole (TMH eyes. TEM disclosed ILM thickening and cellularity in DME as compared to CRVO. Conclusion: Acellular membranes from CRVO maculopathy may be a sequel of acute retinal ischemia. Thickened diabetic ILMs with high cellularity may be related to chronic activation of Muller cells. No obvious influence of ICG or TA on epiretinal cellularity was detected and the dyes seem to have no significant effect on cleavage plane.

  7. The Application of Intensive Longitudinal Methods to Investigate Change: Stimulating the Field of Applied Family Research.

    Science.gov (United States)

    Bamberger, Katharine T

    2016-03-01

    The use of intensive longitudinal methods (ILM)-rapid in situ assessment at micro timescales-can be overlaid on RCTs and other study designs in applied family research. Particularly, when done as part of a multiple timescale design-in bursts over macro timescales-ILM can advance the study of the mechanisms and effects of family interventions and processes of family change. ILM confers measurement benefits in accurately assessing momentary and variable experiences and captures fine-grained dynamic pictures of time-ordered processes. Thus, ILM allows opportunities to investigate new research questions about intervention effects on within-subject (i.e., within-person, within-family) variability (i.e., dynamic constructs) and about the time-ordered change process that interventions induce in families and family members beginning with the first intervention session. This paper discusses the need and rationale for applying ILM to family intervention evaluation, new research questions that can be addressed with ILM, example research using ILM in the related fields of basic family research and the evaluation of individual-based interventions. Finally, the paper touches on practical challenges and considerations associated with ILM and points readers to resources for the application of ILM.

  8. Uus aasta võtab endaga kaasa lõppeva aasta probleemid / Jaana Pikalev

    Index Scriptorium Estoniae

    Pikalev, Jaana

    2006-01-01

    Prognoosid 2007. aastaks transpordi ja logistika vallas. Sisaldab artikleid: Reelika Raamat. Probleemid piiril näivad jätkuvat; Anton Ovsjankin. Transiidi mahud itta kasvavad; Evert Kreek. Teenuste hinnad tõusevad; Olari Rätsep. Vajalik läbimõeldud tarkvara; Enno Aermates. Mahukas kaup kiiresti teele

  9. Tiitelleht olgu asjalik / Oskar Kruus

    Index Scriptorium Estoniae

    Kruus, Oskar, 1929-2007

    2001-01-01

    Arvustus: Veskimägi, Kaljo-Olev. Kahte kappi on ühhetassa maja tarvis... : Eesti raamatukogude ajalugu. Tallinn : K.-O. Veskimägi, 2000 ; Toona, Elin. Rõõm teeb taeva taga tuld : Ernst Enno. Tartu : Ilmamaa, 2000

  10. Rapla noored on märk üle-eestilises kultuuriilmas / Margus Mikomägi

    Index Scriptorium Estoniae

    Mikomägi, Margus, 1956-

    2009-01-01

    13. mail NO99 teatris esietenduvast lavastusest "Pea vahetus", autor ja lavastaja Uku Uusberg, helilooja Pärt Uusberg. Tema muusikat esitab kammerkoor "Head ööd vend". Laulude tekstid: Juhan Liiv ja Ernst Enno. Mängivad: Märt Avandi ja Priit Võigemast

  11. Na vosmom jezhegodnom konkurse titula "lutshsheje betonnoje strojenije" udostoilsja most Puurmani / Eva Kiisler

    Index Scriptorium Estoniae

    Kiisler, Eva

    2008-01-01

    Konkursi "Aasta betoonehitis 2007" võitis Puurmani kaarsild Tallinn-Tartu-Luhamaa maanteel, konstruktorid Siim ja Juhan Idnurm, ehitaja AS Merko Ehitus, projektijuht Tiit Joosti, betooni tarnija AS Rudus Eesti. AS Merko Ehitus kvaliteedijuht Enno Põder ja Tiit Joosti ehituse käigust. Puurmani liiklussõlmest. Aadu Kana ja Toomas Vainola konkursist

  12. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... ATLAS, and Wide-Angle Tail Galaxies in ATLAS · Minnie Y. Mao Rob Sharp D. J. Saikia Ray P. Norris Melanie Johnston-Hollitt Enno Middelberg Jim E. J. Lovell · More Details Abstract Fulltext PDF. Using the Australia Telescope Compact Array (ATCA), ATLAS (Australia Telescope Large Area Survey) is ...

  13. Genetic variation of white clover (Trifolium repens L.) collections ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-05-24

    May 24, 2010 ... Morphological data analysis of white clover populations was coupled with molecular markers of random amplified polymorphic DNA ... relationships among white clover germplasms of China, and four commercial cultivars were included ... and agronomic traits, such as root growth (Ennos, 1985), herbage ...

  14. Toidukaupade eksport on takistatud Venemaa uute nõudmiste tõttu / Silva Männik, Kristina Traks

    Index Scriptorium Estoniae

    Männik, Silva, 1974-

    2004-01-01

    Ilmunud ka: Delovõje Vedomosti 9. juuni lk. 7. Eesti kalatootjatel on takistatud kaubavedu Venemaale, kuna viimane ei aktsepteeri alates 1. juunist varem kooskõlastatud veterinaarsertifikaate. Tekkinud olukorda selgitavad nõustamisfirma Vaela juhataja Enno Aloe ja Viru Kalatööstuse juht Agu Laanemets

  15. Loeti luuletusi Eestist ja Eestile / Krista Kumberg

    Index Scriptorium Estoniae

    Kumberg, Krista, 1959-

    2008-01-01

    Ernst Enno etluskonkursi maakondlikust lõppvoorust. 1.-6. klassi õpilased kandis ette oma loodud luuletusi, esile tõsteti: Eva-Maria Brock, Kristjan Kaljuvee, Lisa-Lote Paadik, Martin Nerman, Sebastian Lehis, Viljar Kaer, Merili Kisant, Grete Grauberg. Vt ka Lääne Elu, 26. veebr., lk. 8

  16. Ajalookonverentsilt "Eesti Vabariigi Valitsus eksiilis" / Liivi Uuet

    Index Scriptorium Estoniae

    Uuet, Liivi, 1947-

    2008-01-01

    15. augustil 2008 toimunud Eesti Vabariigi 90. aastapäevale pühendatud konverentsist Lagedil Eesti Vabadusvõitluse muuseumis. Otto Tiefi valitsuse õiguskantslerist ja Riigiarhiivi ning Riigiraamatukogu direktorist 1925-1936 Richard Övelist ja Vabariigi Valitsuse välisministrist aastatel 1964-1982 August Koernist. Konverentsil osales Eesti Vabariigi Valitsuse eksiilis peaministri asetäitja Enno Penno.

  17. Teatrikirjad : veel kord "Emake maantee / Karl August Hindrey

    Index Scriptorium Estoniae

    Hindrey, Karl August, 1875-1947

    2016-01-01

    Saksa kirjanike näidenditest: Wilhelm Schmidtbonni "Mutter Landstraße: das Ende einer Jugend" ("Emake maantee: ühe nooruse lõpp"), näidendi tõlkis eesti keelde 1911. a. Ernst Enno ja 1920ndatel Heino Anto. Fritz Stavenhagen "Mewsi ema", tõlkinud Anna Haava Vanemuise laval

  18. Kellele sa järgned? : tarbekunst / Tiina Käesel

    Index Scriptorium Estoniae

    Käesel, Tiina, 1943-

    2006-01-01

    Tallinna IV rakenduskunsti triennaal "Kaks lähedast" Eesti Tarbekunsti- ja Disainimuuseumis kuni 21. V. Näitusest (kujundus: 3+1 Arhitektid), ettekannete ja esitluste päevast, näitusekataloogist, plakatist (graafiline kujundus: Enno Piir). Pikemalt Wendy Ramshaw, Urve Küttneri, Kersti Laanmaa ja Tiit Rammuli, Kristi Paapi, Anneli Tammiku ning Tanel Veenre töödest

  19. Naturen i den estniska poesin : från animism och panteism till zenbuddhism / Andres Ehin

    Index Scriptorium Estoniae

    Ehin, Andres, 1940-2011

    2001-01-01

    Orig.: Loodus eesti luules: animismist ja panteismist kuni zen-buddhismini. Tekstis on rootsikeelseid luulenäiteid järgmiste eesti luuletajate loomingust: Kristjan Jaak Peterson, Karl Eduard Sööt, Ernst Enno, Gustav Suits, Henrik Visnapuu, Villem Ridala, Betti Alver, Uku Masing, Bernard Kangro, Kalju Lepik, Ilmar Laaban, Artur Alliksaar ja Hando Runnel.

  20. 23. IV avati EKA galeriis projekti "Network Baltic" laureaatide graafikanäitus

    Index Scriptorium Estoniae

    2003-01-01

    Rahvusvahelise kunstiprojekti "Network Baltic - a new dimension" algatas Grafikenshus Rootsis Mariefredis, Eestist osaleb EKA graafikaosakond, kuraator - Enno Ootsing. Näitusel esinevad Kevin Lytsen Taanist, Kaija Kesa Soomest, internetikonkursil ära märgitud Helen Tago ja Eveli Varik

  1. Tsaari-Venemaa spioon sajanditagusel Siiditeel tuletab meelde ajaloo tähtsust / Marje Aksli

    Index Scriptorium Estoniae

    Aksli, Marje

    2010-01-01

    Kanadas elavast väliseesti päritolu ajakirjanikust, kirjanikust ja analüütikust Eric Enno Tammest ja tema raamatust "The Horse that leaps through clouds", milles on juttu spionaažist, Siiditeest ja tänapäeva Hiina tõusust

  2. Euroopa Inimõiguste Kohtusse avalduse esitamise tingimused ja seda piiravad asjaolud. Eesti Vabariigi vastu Euroopa Inimõiguste Kohtusse esitatud kaebused : [bakalaureusetöö] / Merit Ulvik ; Tartu Ülikool, õigusteaduskond ; juhendaja: Juhani Ko

    Index Scriptorium Estoniae

    Ulvik, Merit

    2003-01-01

    Kaebeõigusest üldiselt, avalduse vastuvõtmise kriteeriumid, reservatsiooni tegemise õigus, Eesti Vabariigi vastu esitatud kaebused (vastuvõetamatuks või osaliselt vastuvõetamatuks tunnistatud kaebused - Arnold Treiali ja Leonid Šestjorkini kaebused ; kaebused, mis said lahendi kohtuotsusega - Vitali Slavgorodski, Enno Tammeri, Tiit Veeberi ja Tõnu Mõtsniku kaebused)

  3. Hinnatõus otsib pääsu. Siseturu seis pessimistlik / Tea Taruste ; kommenteerinud Kalev Kõnn, Meelis Einstein, Aldo Unga

    Index Scriptorium Estoniae

    Taruste, Tea

    2011-01-01

    Ehitusmaterjalide tootjate liidu tegevjuhi Enno Rebase hinnangul on ehitusmaterjalide hinnatõus vältimatu, sest sisendid lähevad kallimaks ja kokkuhoidu pole enam võimalik millegi arvel saavutada, kuid suuremat hinnatõusu võib takistada siseturu väike nõudlus. Vineeri hind on tõusnud 20-30%, OSB tõusis 15%

  4. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... Minnie Y. Mao1 2 3 Rob Sharp2 D. J. Saikia3 4 5 Ray P. Norris3 Melanie Johnston-Hollitt6 Enno Middelberg7 Jim E. J. Lovell1. University of Tasmania, Hobart, 7001, Australia. Australian Astronomical Observatory, Epping, NSW, 1710, Australia. CSIRO Australian Telescope National Facility, Epping, NSW, ...

  5. Ängist kirgastumiseni / Aita Kivi

    Index Scriptorium Estoniae

    Kivi, Aita, 1954-

    2000-01-01

    Sisu : Frank McCourt. Jah, on küll; Kaur Kender. Ebanormaalne; Arnon Grunberg. Helesinised esmaspäevad; Melvin Burgess. Saast; Louis de Bernières. Kapten Corelli mandoliin; Jaergen-Frantz Jacobsen. Barbara; Jayne Ann Krentz. Sügavad veed; Enno Tammer. Uppumatu Estonia

  6. Iskusstvo i dizain / Tatjana Pissareva

    Index Scriptorium Estoniae

    Pissareva, Tatjana

    2004-01-01

    Tallinna Viru Keskuse neljandal korrusel avatakse Baltimaade suurim galerii KUNST ja DISAIN. Ruumi kujundasid Pille ja Raivo Hein. Projektijuht on Ilme Rätsep. Galerii avanäitusel osalevad Erika Tammpere, Ene Pars, Sigrid Kuik, Kadi Pajupuu, Ilme Rätsep, Siiri Tammsalu ja teised

  7. 76 FR 18737 - Defense Transportation Regulation, Part IV

    Science.gov (United States)

    2011-04-05

    ... III business rules include the elimination of the Domestic and International Local Move (dLM and iLM... using the existing DP3 domestic ``dHHG'' market using intrastate/interstate domestic shipment code ``D... Local Moves (iLM) into the DP3 international ``iHHG'' market using a new shipment code of service (COS...

  8. Substitution of Soybean Meal with Indigofera zollingeriana Top Leaf Meal on Egg Quality of Cortunix cortunix japonica

    Directory of Open Access Journals (Sweden)

    F. Faradillah

    2015-12-01

    Full Text Available This research aimed to study the substitution of soybean meal (SBM with Indigofera zollingeriana top leaf meal (ILM in the diet on egg quality of Japanese quails. The experiment used a completely randomized design with five treatments and four replications (ten quails of each replication. The dietary treatment contained five combination of SBM and ILM, R0= diets contained 18% SBM without ILM, R1= diet contained 16.2% SBM and 2.66% ILM, R2= diet contained 14.4% SBM and 5.32% ILM, R3= diet contained 12.6% SBM and 7.98% ILM, R4= diet contained 9% SBM and 13.3% ILM. The results showed that the use of 13.3% ILM (R4 significantly (P<0.05 increased feed consumption, egg weight, yolk colour score, egg cholesterol, and reduced malondialdehyde level. The conclusion of this study was I. zollingeriana top leaf meal could be used as much as 13.3% in the diets. The use of I. zollingeriana top leaf meal could improve the quality of eggs physically and chemically.

  9. Recent development of ionic liquid membranes

    Directory of Open Access Journals (Sweden)

    Junfeng Wang

    2016-04-01

    Full Text Available The interest in ionic liquids (IL is motivated by its unique properties, such as negligible vapor pressure, thermal stability, wide electrochemical stability window, and tunability of properties. ILs have been highlighted as solvents for liquid–liquid extraction and liquid membrane separation. To further expand its application in separation field, the ionic liquid membranes (ILMs and its separation technology have been proposed and developed rapidly. This paper is to give a comprehensive overview on the recent applications of ILMs for the separation of various compounds, including organic compounds, mixed gases, and metal ions. Firstly, ILMs was classified into supported ionic liquid membranes (SILMs and quasi-solidified ionic liquid membranes (QSILMs according to the immobilization method of ILs. Then, preparation methods of ILMs, membrane stability as well as applications of ILMs in the separation of various mixtures were reviewed. Followed this, transport mechanisms of gaseous mixtures and organic compounds were elucidated in order to better understand the separation process of ILMs. This tutorial review intends to not only offer an overview on the development of ILMs but also provide a guide for ILMs preparations and applications. Keywords: Ionic liquid membrane, Supported ionic liquid membrane, Qusai-solidified ionic liquid membrane, Stability, Application

  10. Biomechanical Properties of the Internal Limiting Membrane after Intravitreal Ocriplasmin Treatment.

    Science.gov (United States)

    Vielmuth, Franziska; Schumann, Ricarda G; Spindler, Volker; Wolf, Armin; Scheler, Renate; Mayer, Wolfgang J; Henrich, Paul B; Haritoglou, Christos

    2016-01-01

    To assess the stiffness of the human internal limiting membrane (ILM) and evaluate potential changes of mechanical properties following intravitreal ocriplasmin injection for vitreomacular traction. This is an interventional comparative case series of 12 surgically excised ILM specimens consecutively obtained from 9 eyes of 9 patients after unsuccessful pharmacologic vitreolysis with ocriplasmin. During the same time period, 16 specimens from 13 other eyes without ocriplasmin treatment were harvested during vitrectomy and served as controls. All patients presented with macular holes or vitreomacular traction and underwent vitrectomy with ILM peeling either with or without brilliant blue (BB) staining. All specimens were analyzed using atomic force microscopy with scan regions of 25 × 25 μm. In all specimens, both the retinal side and vitreal side of the ILM were analyzed. Atomic force microscopy revealed no significant differences in elasticity of ILM specimens removed from eyes with or without ocriplasmin treatment. Undulated areas of the retinal side presented stiffer than the vitreal side of the ILM. Topographical mapping of both the vitreal and retinal side of the ILM showed no apparent alteration of the morphology in ocriplasmin-treated eyes compared to untreated eyes. Staining with BB resulted in an increase of tissue stiffness. Intravitreal injection of ocriplasmin does not change biomechanical properties of the human ILM. There is no evidence of a potential enzymatic effect of ocriplasmin interfering with the stiffness of this basement membrane. © 2016 S. Karger AG, Basel.

  11. The intubating laryngeal mask produces less heart rate response to ...

    African Journals Online (AJOL)

    Blind intubation through the ILM using a straight silicone tracheal tube manufactured for specific use with the ILM; 2. Intubation with a size 3 macintosh laryngoscope ... such as in patients with ischaemic heart disease. Key Words: Equipment:intubating laryngeal mask airway; Airway,complications: haemodynamic response ...

  12. Müüte Võrumaast, eikellegimaast, mülkasse vajunud maast / Ilmar Laaban

    Index Scriptorium Estoniae

    Laaban, Ilmar, 1921-2000

    1997-01-01

    Varem ilm. Vaba Eesti, 1954, nr. 1. 1952-1953 ilm. luulekogudest: Kangro, Bernard. Eikellegi maa. Lund : EKK, 1952 ; Kolk, Raimond. Kõiv akna all. Lund : EKK, 1952 ; Grünthal, Ivar. Müüdid mülka põhja kadunud maast. Stockholm : Vaba Eesti, 1953 : Asi, Harri. Tuisusõitja. Toronto : Orto, 1952

  13. Ultrastructure of the membrana limitans interna after dye-assisted membrane peeling.

    Science.gov (United States)

    Brockmann, Tobias; Steger, Claudia; Westermann, Martin; Nietzsche, Sandor; Koenigsdoerffer, Ekkehart; Strobel, Juergen; Dawczynski, Jens

    2011-01-01

    The purpose of this study was to investigate the ultrastructure of the membrana limitans interna (internal limiting membrane, ILM) and to evaluate alterations to the retinal cell layers after membrane peeling with vital dyes. Twenty-five patients (25 eyes) who underwent macular hole surgery were included, whereby 12 indocyanine green (ICG)- and 13 brilliant blue G (BBG)-stained ILM were analyzed using light, transmission electron and scanning electron microscopy. Retinal cell fragments on the ILM were identified in both groups using immunohistochemistry. Comparing ICG- and BBG-stained membranes, larger cellular fragments were observed at a higher frequency in the BBG group. Thereby, the findings indicate that ICG permits an enhanced separation of the ILM from the underlying retina with less mechanical destruction. A possible explanation might be seen in the known photosensitivity of ICG, which induces a stiffening and shrinkage of the ILM but also generates retinal toxic metabolites. Copyright © 2011 S. Karger AG, Basel.

  14. Effect of internal limiting membrane peeling on the development of epiretinal membrane after pars plana vitrectomy for primary rhegmatogenous retinal detachment.

    Science.gov (United States)

    Nam, Ki Yup; Kim, Jung Yeul

    2015-05-01

    To investigate the difference in the occurrence of postoperative epiretinal membranes (ERMs) in vitrectomy for rhegmatogenous retinal detachment with and without peeling of the internal limiting membrane (ILM). The medical records of the 135 patients, who underwent vitrectomy for primary rhegmatogenous retinal detachment from November 2007 to August 2011, were analyzed retrospectively. Of the subjects, 70 patients underwent ILM peeling during the surgery and 65 did not. The best-corrected visual acuity, fundus photograph, and optical coherence tomography were collected 3, 6, and 12 months postoperatively. The relationship between ILM peeling and the preoperative findings of rhegmatogenous retinal detachment and development of a postoperative ERM was analyzed. No ERM occurred in the ILM peeling group, whereas an ERM occurred in 14 of 65 patients who underwent vitrectomy without ILM peeling (21.5%). This difference was significant (P detachment.

  15. Posterior hyaloid detachment and internal limiting membrane peeling assisted by anthocyanins from acai fruit (Euterpe oleracea) and 10 other natural vital dyes: experimental study in cadaveric eyes.

    Science.gov (United States)

    Chen, Jane; Ferreira, Magno Antonio; Farah, Michel Eid; de Carvalho, André Maia; Alves Ferreira, Raquel Eustaquio; de Moraes Filho, Milton Nunes; Souza Lima-Filho, Acácio Alves; Lago, João Henrique G; Sartorelli, Patricia; Rodrigues, Eduardo Buchele; Ferreira, Eber; Peris, Cristiane; Maia, Maurício

    2013-01-01

    The purpose of this study was to determine whether natural dyes facilitate posterior hyaloid detachment (posterior vitreous detachment [PVD]) and retinal internal limiting membrane (ILM) peeling in human eyes. Open-sky vitrectomy with posterior hyaloid and ILM removal was performed in 86 human cadaveric eyes. After core vitrectomy, 11 different dyes were injected into the vitreous cavity to aid hyaloid detachment and ILM removal. The dyes were allowed to settle on the macula for 5 minutes after PVD and were removed by mechanical aspiration. Intraocular forceps were used for ILM peeling, which was confirmed by light microscopy of the peeled tissue. Acai fruit (Euterpe oleracea) extract and 10 additional dyes from plants or animal sources were tested: pomegranate (Punica granatum), logwood (Haematoxylum campechianum), chlorophyll extract from alfalfa (Medicago sativa), cochineal (Dactylopius coccus), hibiscus (Hibiscus rosa-sinensis), indigo (Indigofera tinctoria), paprika (Capiscum annuum), turmeric (Curcuma longa), old fustic (Maclura tinctoria), and grape (Vitis vinifera). The dyes facilitated PVD and ILM peeling. Acai fruit (E. oleracea) extract, logwood (H. campechianum), cochineal (D. coccus), and old fustic (M. tinctoria) facilitated PVD in all cases; dye-assisted PVD was compared with triamcinolone-assisted PVD performed previously in a comparative model. Acai fruit (E. oleracea) extract, cochineal (D. coccus), and chlorophyll extract from alfalfa (M. sativa) showed the best capability for ILM staining; dye-assisted ILM removal was compared with the ILM peeling guided by indocyanine green staining performed previously in a comparative model. Light microscopy confirmed the ILM removal in all cases. Anthocyanin dye of the acai fruit (E. oleracea) and the dyes from cochineal (D. coccus) and chlorophyll extract from alfalfa (M. sativa) resulted in the best capability for posterior hyaloid and ILM staining in human cadaveric eyes and may be a useful tool for

  16. Matrix-assisted laser desorption/ionization mass spectrometric analysis of aliphatic biodegradable photoluminescent polymers using new ionic liquid matrices.

    Science.gov (United States)

    Serrano, Carlos A; Zhang, Yi; Yang, Jian; Schug, Kevin A

    2011-05-15

    In this study, two novel ionic liquid matrices (ILMs), N,N-diisopropylethylammonium 3-oxocoumarate and N,N-diisopropylethylammonium dihydroxymonooxoacetophenoate, were tested for the structural elucidation of recently developed aliphatic biodegradable polymers by matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS). The polymers, formed by a condensation reaction of three components, citric acid, octane diol, and an amino acid, are fluorescent, but the exact mechanism behind their luminescent properties has not been fully elucidated. In the original studies, which introduced the polymer class (J. Yang et al., Proc. Natl. Acad. Sci. USA 2009, 106, 10086-10091), a hyper-conjugated cyclic structure was proposed as the source for the photoluminescent behavior. With the use of the two new ILMs, we present evidence that supports the presence of the proposed cyclization product. In addition, the new ILMs, when compared with a previously established ILM, N,N-diisopropylethylammonium α-cyano-3-hydroxycinnimate, provided similar signal intensities and maintained similar spectral profiles. This research also established that the new ILMs provided good spot-to-spot reproducibility and high ionization efficiency compared with corresponding crystalline matrix preparations. Many polymer features revealed through the use of the ILMs could not be observed with crystalline matrices. Ultimately, the new ILMs highlighted the composition of the synthetic polymers, as well as the loss of water that was expected for the formation of the proposed cyclic structure on the polymer backbone. Copyright © 2011 John Wiley & Sons, Ltd.

  17. Harnessing intrinsic localized modes to identify impurities in nonlinear periodic systems

    Science.gov (United States)

    Thota, M.; Harne, R. L.; Wang, K. W.

    2015-02-01

    Intrinsic localized modes (ILMs) are concentrations of vibrational energy in periodic systems/lattices due to the combined influences of nonlinearity and discreteness. Moreover, ILMs can move within the system and may strongly interact with an impurity, such as a stiffness change, mass variation, etc. Numerous scientific fields have uncovered examples and evidence of ILMs, motivating a multidisciplinary pursuit to rigorously understand the underlying principles. In spite of the diverse technical studies, a characterization of ILM interaction behaviors with multiple impurities in dissipative lattices remains outstanding. The insights on such behaviors may be broadly useful when dynamic measurements are the only accessible features of the periodic system. For instance, one may guide an ILM within the lattice using a deliberately applied and steered impurity and harness the observed interaction behaviors with a second, static (immovable) impurity/defect to identify how the underlying lattice is different at the second, defected site, whether or not one knew the position of the defect a priori. In this spirit, this research studies, analyzes, and characterizes the interaction types amongst an ILM and multiple impurities, and devises a method to identify a static defect impurity using quantitatively and qualitatively distinct interaction phenomena. The method is found to be robust to moderate levels of lattice stiffness heterogeneity and is applicable to monitor various property changes that represent impurities. Finally, experimental studies verify that ILMs interact with multiple impurities in unique ways such that defect features may be effectively identified.

  18. Highly Efficient Delivery of Adeno-Associated Viral Vectors to the Primate Retina.

    Science.gov (United States)

    Boye, Shannon E; Alexander, John J; Witherspoon, C Douglas; Boye, Sanford L; Peterson, James J; Clark, Mark E; Sandefer, Kristen J; Girkin, Chris A; Hauswirth, William W; Gamlin, Paul D

    2016-08-01

    Adeno-associated virus (AAV) has emerged as the preferred vector for targeting gene expression to the retina. Subretinally injected AAV can efficiently transduce retinal pigment epithelium and photoreceptors in primate retina. Inner and middle primate retina can be transduced by intravitreally delivered AAV, but with low efficiency. This is due to dilution of vector, potential neutralization of capsid because it is not confined to the immune-privileged retinal compartment, and the presence of the inner limiting membrane (ILM), a barrier separating the vitreous from the neural retina. We here describe a novel "subILM" injection method that addresses all three issues. Specifically, vector is placed in a surgically induced, hydrodissected space between the ILM and neural retina. In an initial experiment, we injected viscoelastic (Healon(®)), a substance we confirmed was biocompatible with AAV, to create a subILM bleb and subsequently injected AAV2-GFP into the bleb after irrigation with basic salt solution. For later experiments, we used a Healon-AAV mixture to place single, subILM injections. In all cases, subILM delivery of AAV was well tolerated-no inflammation or gross structural changes were observed by ophthalmological examination or optical coherence tomography. In-life fluorescence imaging revealed profound transgene expression within the area of the subILM injection bleb that persisted for the study duration. Uniform and extensive transduction of retinal ganglion cells (RGCs) was achieved in the areas beneath the subILM bleb. Transduction of Müller glia, ON bipolar cells, and photoreceptors was also observed. Robust central labeling from green fluorescent protein-expressing RGCs confirmed their continued survival, and was observed in the lateral geniculate nucleus, the superior colliculus, and the pretectum. Our results confirm that the ILM is a major barrier to transduction by AAV in primate retina and that, when it is circumvented, the efficiency and

  19. Value of internal limiting membrane peeling in surgery for idiopathic macular hole stage 2 and 3: a randomised clinical trial

    DEFF Research Database (Denmark)

    Christensen, U C; Krøyer, K; Sander, B

    2009-01-01

    than 1 year's duration of symptoms. Eyes were randomised to (1) vitrectomy alone without retinal surface manipulation, (2) vitrectomy plus 0.05% isotonic Indocyanine Green (ICG)-assisted ILM peeling or (3) vitrectomy plus 0.15% Trypan Blue (TB)-assisted ILM peeling. Main outcomes were hole closure...... after 3 and 12 months and best-corrected visual acuity after 12 months. RESULTS: 78 eyes were enrolled. Primary closure rates were significantly higher with ILM peeling than without peeling for both stage 2 holes (ICG peeling 100%, non-peeling 55%, p = 0.014) and for stage 3 holes (ICG peeling 91%, TB...

  20. Muusika / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2005-01-01

    Operatsioon B. Eesti Lastekoor võitis Varssavis koorifestivalil noortekooride kategoorias esikoha. 13. XI toimub Teatri- ja Muusikamuuseumis kontsert "J. S. Bachi minimaraton". Tubin Saksamaal ja Soomes. Stockholmi kontserdimaja korraldatud festivali nimiheliloojaks on tänavu John Adams. Olari Elts Riias ja Viinis. Indrek Laul kutsuti esinema Bostoni Televisiooni, kuhu oli selleks puhuks toodud Estonia klaver. Rahvusraamatukogu muusikasaalis avatakse näitus "Enno ja Viive Mäemetsa kingitus Eesti Rahvusraamatukogule: 10 aastat = 500 CDd"

  1. Aasta betoonehitise žürii kommentaarid võistlustöödele ja võitjaile / Eva Kiisler, Maritta Koivisto, Angel Andla...[jt.] ; intervjueerinud Mari Sarv ; kommenteerinud Mart Riikoja

    Index Scriptorium Estoniae

    2009-01-01

    Konkursile "Aasta Betoonehitis 2008" annavad hinnangu Eva Kiisler (ajakirja "Ehitaja" peatoimetaja), Maritta Koivisto (Soome ajakirja "Betoni" peatoimetaja"), Angel Andla (Eesti Ehitusettevõtjate Liit), Heiki Meos (Eesti Ehitusinseneride Liit), Siim Sultson ("Äripäeva" ehitusvaldkonna toimetaja), Toomas Laur (Eesti Betooniühing), Ike Volkov (Eesti Arhitektide Liidu esimees), Mauno Inkinen (Eesti Projektbüroode Liit), Enno Rebane (Eesti Ehitusmaterjalide Tootjate Liidu tegevdirektor). Mart Riikoja žürii tööst

  2. Kunstiakadeemia - 85 / Reet Varblane

    Index Scriptorium Estoniae

    Varblane, Reet, 1952-

    1999-01-01

    28. XI tähistas Eesti Kunstiakadeemia oma 85. aastapäeva. Kunstihariduse tulevikule pühendatud paneeldiskussioonist Sakala keskuse väikeses saalis, pressikonverentsist, pidulikust aktusest. Kunstiakadeemia esimesteks audoktoriteks promoveeriti Boris Bernshtein, Kaljo Põllu, Enno Hallek, Ilja Kabakov. Auliikmeteks nimetati Mari Adamson, Leo Gens, Leili Kuldkepp, Helene Kuma, Paul Luhtein, Arseni Mölder, Evald Okas, Helmut Oruvee, Bruno Tomberg, Jaan Vares. Juubelialbumi kujundas Jüri Kaarma, ajaloolise ülevaate kirjutas Leo Gens

  3. A new transmucosal drug delivery system for patients with breakthrough cancer pain: the fentanyl effervescent buccal tablet

    OpenAIRE

    Freye, Enno

    2008-01-01

    Enno FreyeCenter of Ambulatory Pain Medicine, Neuss-Uedesheim, GermanyAbstract: Breakthrough pain, a transitory severe pain with the background of otherwise controlled persistent pain has a prevalence between 52% and 67% in outpatients with cancer. Medications for such sudden-onset pain require non-invasive delivery of a potent and short-acting opioid for rapid pain relief. Although oral transmucosal delivery of fentanyl citrate (OTFC) has been shown to provide better pain relief than a typic...

  4. Eesti luulet okastraataia tagant / Eduard . Krants pseud ; E. Krants

    Index Scriptorium Estoniae

    Krants, Eduard, pseud.

    1999-01-01

    rets. rmt.: Onton, Ilmar. Ebakõlad : luuletused 1945-1971. Trt. : Anamnesia, 1993. 79 lk.; Üllaste, Leenart. Lind tormis. Rakvere : Anamnesia, 1994. 139 lk.; Sõelsepp, Venda. Narilaulud. Pärnu : Anamnesia, 1993. 217 lk.; Piir, Enno. Sunnitöölise Mekka : [ luuletused]. Viljandi : Anamnesia, 1994. 225 lk.; Pihlapuu, Artur. Püramiidi siluett : valik luulet 1941-1989. Võru : Anamnesia, 1995. 246 lk.; Uibo, Enn. Testament : valik luulet 1930-1965. Tln. : Anamnesia, 1995. 301 lk.

  5. Gaia tülikad tarkusehambad / Toomas Paul

    Index Scriptorium Estoniae

    Paul, Toomas, 1939-

    2006-01-01

    Inimese kui fenomeni tähendusest kosmoses evolutsiooniteooria ja teoloogia vaatenurkadest. Ilm. ka: Paul, Toomas. Multiversumi mull // Pastishsh & popurrii : ilmavaatlusi / Paul, Toomas. - [Tallinn] : Oomen, 2007. - Lk. 7-13

  6. Kodakondsus - kas integratsiooni eeldus või tulemus? / Klara Hallik

    Index Scriptorium Estoniae

    Hallik, Klara

    2000-01-01

    Eestlaste ja mitteeestlaste ootused kodakondsuspoliitika suhtes on jätkuvalt vastandlikud. Ilm. ka: Integration of Estonian Society : monitoring 2000.- Tallinn, 2000 ; Integratsija Estonskogo obshtshestva : monitoring 2000.- Tallinn, 2000

  7. Estonian literature and a brave new world : a postmodern turn? / Piret Viires

    Index Scriptorium Estoniae

    Viires, Piret, 1963-

    2006-01-01

    Ilm. ka väljaandes: Different inputs - same output? : autonomy and dependence of the arts under different social-economic conditions / ed C. D. Hasselblatt - Maastricht : Shaker, 2006. (Studia Fenno-Ugrica Groningana ; 3)

  8. President Arnold Rüütel osutus heaks modelliks / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2003-01-01

    Iseseisvuspäeval modelleeriti Pärnu Uue Kunsti Muuseumis savist Eesti presidente, juhendajad Ilme ja Riho Kuld. Pärnu Kunstide Maja õpilane Evelyn Bernard tegi president Arnold Rüütli saviskulptuuri

  9. Kalevipoeg - ein Interview mit Prof. Dr. Peter Petersen / Peter Petersen ; interv. Laine Paavo

    Index Scriptorium Estoniae

    Petersen, Peter

    2005-01-01

    Kalevipoja uuest saksakeelsest väljaandest: Kalevipoeg : das estnische Nationalepos / in der Übersetzung von Ferdinand Löwe ; herausgegeben von Peter Petersen Ilm. andmed Stuttgart ; Berlin : Mayer, 2004.

  10. Comeniuse projekt tutvustas grafiti kirevat maailma / Liisi Seil

    Index Scriptorium Estoniae

    Seil, Liisi, 1971-

    2007-01-01

    Viljandi Jakobsoni gümnaasiumi õpilaste osalemisest projektis "Euroopa linnagrafiti - ajaloo, loovuse ja graafilise vandalismi ilming". Kolm aastat on koos Itaalia, Belgia ja Läti noortega uuritud grafitit ja selle avaldumisvorme

  11. Teaduse mälu / Peeter Torop

    Index Scriptorium Estoniae

    Torop, Peeter, 1950-

    1999-01-01

    Varem ilm.: Vikerkaar 1993, nr. 8. Viited ja märkused lk. 474-476. Vene formalismist (vormikoolkonnast): Poeetilise Keele Uurimise Seltsist Peterburis (OPOJAZ, asut. 1914) ja Moskva Lingvistikaringist (1915). Viktor Shklovski (1893-1984)

  12. Blogid Rapla maakonna rahvaraamatukogudes / Maie Jakobson

    Index Scriptorium Estoniae

    Jakobson, Maie

    2009-01-01

    Rapla maakonna raamatukoguhoidjate arvamus ajaveebi pidamisest, eelnevatest koolitustest. Arvamust avaldavad: Helve Lehtmaa Laukna raamatukogust, Ilme Säde Käru ramatukogust, Tiina Vaher ja Maie Kalmiste Kehtna raamatukogust, Irma Robam Vahastu raamatukogust ning Mariina Madisson Lelle raamatukogust

  13. Beyond digital labyrinth : rethinking literary history in the age of new media / Marin Laak

    Index Scriptorium Estoniae

    Laak, Marin, 1964-

    2006-01-01

    Ilm. ka väljaandes: Different inputs - same output? : autonomy and dependence of the arts under different social-economic conditions / ed C. D. Hasselblatt - Maastricht : Shaker, 2006. (Studia Fenno-Ugrica Groningana ; 3)

  14. Maapaos mõtlik metsarada : luulet 1954-55 / Ilmar Laaban

    Index Scriptorium Estoniae

    Laaban, Ilmar, 1921-2000

    1997-01-01

    Varem ilm. Vaba Eesti, 1956, nr. 1. Rets. rmt.: Suits, Gustav. Kõik on kokku unenägu. 2. tr. Stockholm Vaba Eesti, 1954; Under, Marie. Sädemed tuhas. Toronto : Orto, 1954; Kangro, Bernard. Suvihari. Lund : EKK, 1955

  15. New York, rändurite linn / Kadri Kerge

    Index Scriptorium Estoniae

    Kerge, Kadri

    2016-01-01

    New York on linn, mille elanikkond ja ruum on pidevas muutumises. Ehitustegevuse tulemusena on uue ilme saanud kõik linnaosad. Aktuaalseim teema New Yorgi arhitektuuriringkondades ja ehituses on nn. ultrapilvelõhkujatega seonduv

  16. Urozhainõi sezon / Aleksei Zhigulin

    Index Scriptorium Estoniae

    Zhigulin, Aleksei

    2006-01-01

    Lohusuu talunik Ülo Karro, Eesti Põllumajandus-Kaubanduskoja spetsialist Kristi Varrik ja Jõgeva Sordiaretuse Instituudi ekspert Ilme Tiitus tänavusest viljasaagist, teravilja kokkuostust ning teraviljakasvatusest Eestis. Tabel: Teravilja kokkuostuhinna muutumisest Eestis (2002-2005)

  17. Kõiki vene lasteaedade mudilasi ootavad eesti keele tunnid = Malõshei v russkihh detsadahh zhdut uroki estonskogo jazõka / Kai Kalamees

    Index Scriptorium Estoniae

    Kalamees, Kai

    2008-01-01

    Venekeelsetes lasteaedades tuleb alates 2009. aasta sügisest tagada eesti keele õpetamine. Kommenteerinud haridusminister Tõnis Lukas ja Tallinna abilinnapea Kaia Jäppinen. Ilm. ka: Postimees (vene k.)

  18. Maju lumes : uudisproosat EKK-lt / Ilmar Laaban

    Index Scriptorium Estoniae

    Laaban, Ilmar, 1921-2000

    1997-01-01

    Varem ilm. Vaba Eesti, 1952, nr. 4.Rets rmt.: Talve, Ilmar. Maja lumes : [romaan]. Lund : Eesti Kirjanike Kooperatiiv, 1952 ; Gailit, August. Kas mäletad, mu arm? : [romaan novellides]. Lund : Eesti Kirjanike Kooperatiiv, 1951

  19. Arno Rafael Cederberg ja Eesti ajalooteadus / Hans Kruus

    Index Scriptorium Estoniae

    Kruus, Hans, 1891-1976

    2005-01-01

    Soome ajalooprofessorist Arno Rafael Cederbergist (1885-1948). Tartu Ülikoolis töötades oli tema peamine õppe-ja uurimisaine Eesti ja Põhjamaade ajalugu. Ilm.: Eesti Kirjandus, 1935, nr. 6., lk. 254-255

  20. Plaat : Pop & Rock, Õlu, Crossover, Klassika

    Index Scriptorium Estoniae

    1999-01-01

    Uutest heliplaatidest. Eesti plaadid : Ivo Linna & Rock Hotel "Kõva ketas", Väikeste Lõõtspillide Ühing "See terve ilm on imelik", Kuldsed Lindid "Ootamatud sõnad", Laine Mustasaar "Naise elu ja armastus"

  1. Inimloetav ja masinloetav : mõistete analüüs / Priit Parmakson

    Index Scriptorium Estoniae

    Parmakson, Priit

    2011-01-01

    Infoühiskonnas on iseloomulik struktuuristatud, masintöötlemisele orienteeritud teabe osakaalu kasv, mille ilming on ka Eesti avalikus sektoris mitmes valdkonnas käsil olev sellesuunaline IT töö

  2. Kui Jõnn läks Tartust merele / Jaak Allik

    Index Scriptorium Estoniae

    Allik, Jaak, 1946-

    2004-01-01

    J. Smuuli "Kihnu Jõnni" kahest lavastusest - 1964 Eesti Draamateatris V. Panso lavastuses K. Karmiga peaosas ja 1965 Vanemuises K. Irdi lavastuses E. Salulahega peaosas. Arvustus varem ilm. ajalehes "Tartu Riiklik Ülikool", 14. 05. 1966

  3. Siim Nestor soovitab : Need on meie külalised / Siim Nestor

    Index Scriptorium Estoniae

    Nestor, Siim, 1974-

    2004-01-01

    Popmuusikaüritustest Tallinna klubides: Privé's 1. apr.,"1ÖÖ%" Von Krahlis (ekstravaganza festivali Hea Uus Ilm raames) ja "Depeche Mode Party" Hollywoodis 4. apr., "Tramm ja Buss" BonBonis 7. aprillil

  4. Kirjandus kui terrorist : võimu suhe loomingusse ei sõltu süsteemist / Jüri Ehlvest

    Index Scriptorium Estoniae

    Ehlvest, Jüri, 1967-2006

    2002-01-01

    Kommentaarid Mati Sirkelilt ja Kaur Kenderilt varem ilm. artiklitest. Vastuseks art.: Mati Sirkel. "Milline on meie vaimu seis", Postimees 19. okt.; Kaur Kender. Tüütu ja tülikas armastus", Postimees 26. okt.

  5. Relationships between bone mineral density and new indices of body composition in young, sedentary men and women

    Directory of Open Access Journals (Sweden)

    Anna Kęska

    2018-03-01

    The use of IFM and ILM in the present study, allowed the observation that in young adults lean body mass was associated with BMD, regardless of gender, while fat mass is significant for bone mineral density only in women

  6. Displacement of fovea toward optic disk after macular hole surgery with internal limiting membrane peeling

    OpenAIRE

    Ohta, Kouichi; Sato, Atsuko; Senda, Nami; Fukui, Emi

    2017-01-01

    Kouichi Ohta, Atsuko Sato, Nami Senda, Emi Fukui Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Nagano, Japan Purpose: The purpose of this study was to demonstrate a displacement of the foveal depression toward the optic disk after idiopathic macular hole (MH) surgery with internal limiting membrane (ILM) peeling.Methods: Two patients with a unilateral MH developed an MH in the fellow eyes. Vitrectomy with ILM peeling was performed on the fellow...

  7. Retinal Damage Induced by Internal Limiting Membrane Removal

    Directory of Open Access Journals (Sweden)

    Rachel Gelman

    2015-01-01

    Full Text Available The internal limiting membrane (ILM, the basement membrane of the Müller cells, serves as the interface between the vitreous body and the retinal nerve fiber layer. It has a fundamental role in the development, structure, and function of the retina, although it also is a pathologic component in the various vitreoretinal disorders, most notably in macular holes. It was not until understanding of the evolution of idiopathic macular holes and the advent of idiopathic macular hole surgery that the idea of adjuvant ILM peeling in the treatment of tractional maculopathies was explored. Today intentional ILM peeling is a commonly applied surgical technique among vitreoretinal surgeons as it has been found to increase the rate of successful macular hole closure and improve surgical outcomes in other vitreoretinal diseases. Though ILM peeling has refined surgery for tractional maculopathies, like all surgical procedures it is not immune to perioperative risk. The essential role of the ILM to the integrity of the retina and risk of trauma to retinal tissue spurs suspicion with regard to its routine removal. Several authors have investigated the retinal damage induced by ILM peeling and these complications have been manifested across many different diagnostic studies.

  8. A second-generation ionic liquid matrix-assisted laser desorption/ionization matrix for effective mass spectrometric analysis of biodegradable polymers.

    Science.gov (United States)

    Berthod, Alain; Crank, Jeffrey A; Rundlett, Kimber L; Armstrong, Daniel W

    2009-11-01

    A second generation ionic liquid matrix (ILM), N,N-diisopropylethylammonium alpha-cyano-4-hydroxycinnamate (DEA-CHCA), was developed for the characterization of polar biodegradable polymers. It is compared with five solid matrices typically used for the characterization of these polymers and one other new ILM. It is shown that use of the ILM, DEA-CHCA, allows maximum signal with minimum laser intensity which minimizes polymer degradation. In these conditions, the DEA-CHCA ILM is able to assist in the ionization of analytes in an efficient but soft manner. These qualities produce spectra that allow an accurate and sensitive determination of the number average molecular weights, weight average m.w., and polydispersity index of labile polar polymers. With such polymers, many solid matrices produce spectra showing extensive polymer degradation leading to the underestimation of molecular weights. The distribution of intact analyte peaks obtained with the ILM DEA-CHCA allows for identification of the fine structure of complex copolymers. ILMs were much less susceptible to effects of extraction delay times on molecular weight determination than were solid matrices. The liquid nature of the matrix is an important reason for the outstanding results obtained for labile analyte polymers. No comparable results could be obtained with any known solid matrices or other ILMs. In many cases, the manufacturers' listed molecular weights and polydispersity measurements for biodegradable polymers are determined by size-exclusion chromatography and the data obtained by that method may differ considerably from the high-precision matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF-MS) results presented here. Copyright 2009 John Wiley & Sons, Ltd.

  9. Shepherding intrinsic localized modes in micro-mechanical arrays

    Science.gov (United States)

    Sievers, Albert

    The energy profiles of intrinsic localized modes (ILMs) in periodic physical lattices with nonlinear forces resemble those of localized vibrational modes at defects in a harmonic lattice but, like solitons, they can propagate; however, in contrast with solitons they loose energy as they move through the lattice - the more localized the excitation the faster the energy loss. One of our experimental studies with micro-mechanical arrays involves steady state locking of ILMs, and their interactions with impurities. By measuring the linear response spectra of a driven array containing an ILM both the dynamics of bifurcation transitions and the hopping of vibrational energy have been connected to the transition properties of soft modes. Recently the search for a completely mobile ILM has focused attention on minimizing the resonance interaction that occurs between the localized excitation and small amplitude plane wave modes. Via simulations we demonstrate that when more than one type of nonlinear force is present their Fourier components can often be designed to cancel against each other in the k-space region of the plane wave dispersion curve, removing the resonance. The end result is super-transmission for an ILM in a discrete physical lattice. Such an engineered, intrinsic, low loss channel may prove to be a useful property for other physical systems treated within a tight binding approximation. In collaboration with M. Sato.

  10. Pathology of the macular hole rim in flat-mounted internal limiting membrane specimens.

    Science.gov (United States)

    Gandorfer, Arnd; Scheler, Renate; Haritoglou, Christos; Schumann, Ricarda; Nentwich, Martin; Kampik, Anselm

    2009-09-01

    The purpose of this study was to image the pathology of vitreoretinal adhesion and cellular proliferation at the macular hole rim for a better understanding of macular hole formation. Internal limiting membrane (ILM) peeling, ILM flat-mount preparation, phase contrast and interference microscopy, transmission electron microscopy, and immunocytochemistry of the macular hole rim were performed in 10 eyes with idiopathic macular holes. Phase contrast and interference microscopy showed cellular proliferation on the vitreal side of the ILM in all specimens. There were single cells in three eyes, cell clusters in six eyes, and continuous proliferation in one eye. Surrounding the macular hole, only a few cells were present. Cellular proliferation started at a distance of 80 mum to 940 mum from the macular hole edge. Transmission electron microscopy showed vitreous adhesion at the macular hole rim. In ultrastructural terms, there was a continuous insertion of vitreous collagen fibers into the ILM. Immunocytochemistry was positive for collagen type II, laminin, and fibronectin in the area of vitreous attachment. Cells were stained with markers for glial cells, retinal pigment epithelial cells, and hyalocytes. There is ultrastructural evidence that macular hole formation is caused by an insertion of the cortical vitreous into the foveal ILM. Vitreous collagen fibers may exert vitreofoveal traction, resulting in a foveal tear. Cellular proliferation is not continuously distributed surrounding the macular hole but separated from the macular hole edge and seems to originate from cell clusters forming centers of proliferation distant from the macular hole rim.

  11. Autologous Transplantation of the Internal Limiting Membrane for Refractory Macular Hole following Ruptured Retinal Arterial Macroaneurysm: A Case Report

    Directory of Open Access Journals (Sweden)

    Yumi Iwakawa

    2018-02-01

    Full Text Available Purpose: To report a case of macular hole (MH secondary to a retinal arterial macroaneurysm (RAMA which was successfully treated with an autologous transplantation of internal limiting membrane (ILM. Case Report: An 87-year-old female presented with a sudden decrease in central vision in the right eye. A fundus examination revealed a RAMA in the superonasal macular region, a subretinal hemorrhage (SRH, involving the macula, and a sub-ILM hemorrhage. A pars plana vitrectomy (PPV was performed. Intraoperatively, an MH filled with coagulum was detected. We tried to blow off and drain the SRH with a current of BSS and a gentle suction with a 27-gauge vitreous cutter from the MH, but some amount of SRH at the bottom of the MH remained. The ILM was peeled off for 2 disc diameters around the MH. The vitreous cavity was filled with air at the end of the operation. Two weeks after the surgery, the MH was not closed. One month following the initial PPV, a second PPV was performed to achieve closure of the MH. Results: An autologous transplantation of ILM was performed as second PPV. Six months after the final surgery, the MH was successfully closed and the best-corrected decimal visual acuity was 0.6. Conclusions: Autologous ILM transplantation can be an effective treatment option for MH closure following RAMA rupture.

  12. Reservsõjaväelasele Leo Kunnasele anti Stalkeri romaaniauhind / Kalev Kask, Kaarel Kressa

    Index Scriptorium Estoniae

    Kask, Kalev

    2009-01-01

    Eesti Ulmeühingu Stalkeri-nimelised auhinnad jaotusid järgmiselt: algupärase romaani auhind - Leo Kunnas (romaani "Gort Ashryn" 1. osa "Enne viimast sõda"), algupärase jutu auhind - Indrek Hargla ("Minu päevad Liinaga", ilm. Looming, 2008, nr. 8), algupärase lühijutu auhind - Laur Kraft ("Ultima Cthule", ilm. võrguajakirjas Algernon), tõlkeromaani auhind - Sergei Lukjanenko ("Öine Vahtkond"), kogumiku auhind - Poul Anderson ("Taevarahvas"), tõlkejutu auhind - Paolo Bacigalup ("Flööditüdruk")

  13. Comparisons of foveal thickness and slope after macular hole surgery with and without internal limiting membrane peeling

    Directory of Open Access Journals (Sweden)

    Ohta K

    2018-03-01

    Full Text Available Kouichi Ohta, Atsuko Sato, Nami Senda, Emi Fukui Department of Ophthalmology, Matsumoto Dental University, Nagano, Japan Background: We have shown that the foveal contour was asymmetrical after idiopathic macular hole (MH closure by pars plana vitrectomy (PPV with internal limiting membrane (ILM peeling. The purpose of this study was to determine whether these morphological changes differ in eyes after PPV without ILM peeling. Methods: Ten eyes of 10 patients that underwent PPV without ILM peeling and 12 eyes of 11 patients with ILM peeling were studied. The MH in all eyes was <400 µm in diameter. Six months after the PPV, the macular thickness and foveal slope around the closed MH were determined by spectral-domain optical coherence tomography. The thickness of the ganglion cell complex was measured by another spectral-domain optical coherence tomography instrument >6 months after the surgery. Results: The mean parafoveal retinal thickness in the non-peeled group was 367.1 µm in the nasal (N, 353.0 µm in the temporal (T, 366.9 µm in the superior (S, and 357.3 µm in the inferior (I sectors. The T, S, and I sectors were significantly thicker than the corresponding sectors in the ILM peeled group (p=0.0008, 0.003, and 0.03, respectively. The mean ganglion cell complex was thicker not only in the N sector but also in the T sector in the non-peeled group. The mean retinal slopes in the non-peeled group (N, 40.2°; T, 37.6°; S, 41.2°; I, 39.5° were flatter than those in the peeled group (N, 52.3°; T, 43.6°; S, 50.8°; I, 51.9°; p=0.009, 0.09, 0.008, and 0.017, respectively. Conclusion: The symmetrical fovea after MH surgery in the non-ILM peeled eyes indicates that the asymmetrical fovea after ILM peeling was probably due to the ILM peeling. Keywords: idiopathic macular hole, foveal contour, internal limiting membrane, vitrectomy

  14. Bacterial growth efficiency in the tropical estuarine and coastal waters of Goa, southwest coast of India

    Digital Repository Service at National Institute of Oceanography (India)

    Ram, A.; Nair, S.; Chandramohan, D.

    that affect or regulate them? To answer the above ques tions, a series of experiments were conducted with both estuarine and coastal waters using short incubation peri ods [4, 36], In this paper we report for the first time the growth efficiencies...M and 0.62 IlM, respectively. The minimum and maximum phosphate levels in the es· tuarine waters were from 0.85 to 1.58 J.lM. The ammonium concentration ranged from 0.08 to 4.21 IlM. In general, the nutrient concentration was comparatively higher...

  15. Intrinsic localized modes in arrays of atomic-molecular Bose-Einstein condensates

    International Nuclear Information System (INIS)

    Abdullaev, F.Kh.; Konotop, V.V.

    2003-01-01

    The existence of strongly localized matter solitons, intrinsic localized modes (ILM's), in an array of atomic-molecular Bose-Einstein condensates (AMBEC's) is shown. The theory is based on the Wannier function expansion of the system order parameter and predicts the possibility of strong localization of the atomic and molecular components whose relative populations are determined by the Raman detuning parameter and by the atom-molecule conversion rate. ILM's can possess different symmetries and spatial distributions of the components. In this context AMBEC arrays can be viewed as potential compressors and separators of atomic and molecular condensates

  16. Combined epiretinal and internal limiting membrane peeling facilitated by high dilution indocyanine green negative staining

    Directory of Open Access Journals (Sweden)

    Mark M Kaehr

    2015-01-01

    Full Text Available We describe the utilization of indocyanine green (ICG dye to facilitate combined/en bloc removal of epiretinal membranes (ERM along with internal limiting membranes (ILM. The method utilizes a highly diluted preparation of ICG in dextrose water solvent (D5W. Elimination of fluid air exchange step facilitating staining in the fluid phase and low intensity lighting help minimize potential ICG toxicity. The technique demonstrates how ICG facilitates negative staining of ERMs and how ILM peeling concomitantly can allow complete and efficient ERM removal minimizing surgical time and the necessity for dual or sequential staining.

  17. Arhitektuurivõistlused 2008 / Mait Väljas

    Index Scriptorium Estoniae

    Väljas, Mait

    2008-01-01

    Võistluste tulemused: Pekingi saatkonnahoone: I preemia - A. Põime, L. Põime, L. Vaimel; Riia saatkonnahoone: I - L.-K. Stöör, Ü.-T. Stöör, H. Urb; Eesti Kunstiakadeemia uus õppehoone: I - SEA + Effekt (Taani); Eesti Maaülikooli Kreutzwaldi 5 õppehoone juurdeehitis: I - P. Loo, J. Skolimowski, L. Vene, K. Kruuse (KAMP Arhitektid); TÜ Viljandi Kultuuriakadeemia loomeinkubaatori ja lavakunstide õppehoone: I - S. Vallner, H. Urb, I. Peil, H. Lass, S.-M. Mändmaa (Kavakava); Tamula järve ranna-ala mahuline planeering: I - K. Enno, L. Luhse, M. Zeleznova, R. Ailt (K. Enno Arhitektuuribüroo); Tartu pärmivabriku kvartali arhitektuurivõistlus: võidutöö - Atelier Thomas Pucher / Bramberger Architects (Austria); Paldiski mnt. 50 kinnistu ja lähiala: I-II - T. Laigu, K. Ojaliiv, M. Rass, A. Uukado (QP Arhitektid); maastikuarhitektuuri võistlus "Eesti Maaülikooli Tähtvere linnaku välialad": I - H. Runnel, T. Ong; Tartu rahu tähisala kujundus: I - M. Kinks, K. Süda; Veneetsia XI rahvusvahelise arhitektuuribiennaali ideekavandi võistlus: I - M. Kask, R. Lõoke, N. Külm; aasta betoonehitis 2007 - Puurmani kaarsild, konstruktorid S. Idnurm, J. Idnurm; Eesti parim puitehitis 2008: eramu Loobul - R. Vaiksoo; võistluse "Eramu 2006-2007" peapreemia: villa Paldiskis - S. Vallner, I. Peil

  18. Aafrika 50 aastat: pool sajandit raisku lastud vabadust / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2010-01-01

    50 aastat tagasi iseseisvus 17 Aafrika riiki. Autor käsitleb uute riikide tekkimist Aafrikas ning Aafrika tänapäeva: 9 Aafrika riiki on poliitiliselt vabad, 24 riiki osaliselt vabad ehk piiratud demokraatiaga, 20 riiki aga on libisenud despootlike hulka, uus ilming Aafrikas on tervete riikide kokkuvarisemine. Kaardid

  19. Failure Time Distributions: Estimates and Asymptotic Results.

    Science.gov (United States)

    1980-01-01

    mathematical termos implies that the hazard rate function is oonvex which, together with the three periods discussed earlier, is frequently referred to...of a events. Journal of Applied Probability, Zidek, J.V., Navin, F.P.D. and Lockhart, R. (1979). Statistics of extremes: an alternate method with application to bridge design codes. Tecknometrics, 21, 185-191. .. . ILMED

  20. 75 FR 16445 - Defense Transportation Regulation, Part IV

    Science.gov (United States)

    2010-04-01

    ...: DOD has issued Phase III Final-Draft Business Rules for the Defense Personal Property Program (DP3) in the Defense Transportation Regulation (DTR) Part IV (DTR 4500.9R). The Phase III Business Rules... and International Local Moves (dLM and iLM) and International Intra-Country Moves (iCM). DP3 Phase III...

  1. Kolm kogu kassetis : [retsensioon] / Peeter Tulviste

    Index Scriptorium Estoniae

    Tulviste, Peeter, 1945-2017

    1998-01-01

    Varem ilm.: Looming, 1969, nr. 4. Rets. rmt.: Noored autorid 1967. Nikolai Baturin. Maa-alused järved : luuletusi 1963-1967. Tallinn : Eesti Raamat, 1968 ; Andres Ehin. Hunditamm : luuletusi 1959-1966. Tallinn : Eesti Raamat, 1968 ; Albert Koeney. Vihmade vaikus : luuletusi 1965-1966. Tallinn : Eesti Raamat, 1968

  2. Fantaasia killapeod : [rets.] / Ain Kaalep

    Index Scriptorium Estoniae

    Kaalep, Ain, 1926-

    1997-01-01

    Ilm.: Looming 1968, nr. 10, lk. 1592-1595 . Rets. rmt.: Alliksaar, Artur. Nimetu saar. Tallinn : Perioodika, 1966. 80 lk. (Loomingu Raamatukogu; 1966, 7); Alliksaar, Artur. Olematus võiks ju ka olemata olla. Tallinn ; Perioodika, 1968. 80 lk. (Loomingu Raamatukogu; 1968, 9/10).

  3. Jüri Uluots jõudis võõrsilt koju / Rein Hanson

    Index Scriptorium Estoniae

    Hanson, Rein, 1948-

    2008-01-01

    Endise Eesti peaministri ja peaministri presidendi ametis Jüri Uluotsa ja tema abikaasa ning poja säilmed maeti 31. augustil 2008 Kirbla kalmistule. Ümbermatmise tseremoonial esines kõnega ka president Toomas Hendrik Ilves. Vt. samas foto: Koguduse juhatuse esimees vallavanem Anu-Lii Jürman tervitab Kirbla kiriku trepil Eesti Vabariigi presidenti Toomas Hendrik Ilvest

  4. J. Poska 9 üürimaja uus tulemine / Mariette Aavik

    Index Scriptorium Estoniae

    Aavik, Mariette

    2012-01-01

    1930. aastate teisel poolel ehitatud hoonest, mis taastati õigusjärgse pärija, maja ehitaja pojapoja Väino Vaheri poolt just üürimajana. Fassaadi reastaureerimisel taastati selle ajaloolilne ilme. Endise 12 korteri asemel jäi peale restaureerimist hoonesse 8 korterit. Sisearhitektuuris kasutati omaniku soovil võimalikult palju looduslähedasi viimistlusmaterjale

  5. Shavian / Pent Nurmekund

    Index Scriptorium Estoniae

    Nurmekund, Pent, 1906-1996

    1997-01-01

    G. B. Shaw' näidendi "Androkles ja lõvi" ilmus erilises foneetilises tähestikus, mille lõid Kingsley Read ja Peter MacCarthy, täites G. B. Shaw' testamendi ühte punkti. Varem ilm. ajal. Edasi, 1962, 18. dets.

  6. Toxicity profiles of subretinal indocyanine green, Brilliant Blue G, and triamcinolone acetonide: a comparative study

    DEFF Research Database (Denmark)

    Ejstrup, Rasmus; Dornonville de la Cour, Morten; Heegaard, Steffen

    2012-01-01

    BACKGROUND: This study introduces a novel porcine model to examine the histopathological and electrophysiological consequences of retinotoxicity exerted by dyes commonly used for internal limiting membrane (ILM) staining. METHODS: Indocyanine green (ICG) 0.5 mg/ml, Brilliant Blue G (BBG) 0.25 mg/...

  7. Bagatellid : maailm / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2008-01-01

    Bachi ja Mozarti uued ilmed. Hilary Hahnilt ja Mayuko Kamiolt uued plaadid. Lahkus tenor Giuseppe di Stefano. Henri Dutilleux pälvis Kuningliku Filharmooniaühingu kuldmedali. Inglismaa vanim spinett müügil. Guarneri hinnaline viiul helises taas

  8. Animafilminduse algusotsast 1 / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2007-01-01

    Maailma esimestest animafilmidest : Albert Smith'i "The Humpty Dumty Circus" (USA, 1898), esimene joonisfilm "Naljakate nägude humoorikad ilmed" (Humorous Phases of Funny Faces") - looja Stuart Blackton (USA, 1906). Esimese joonisseriaali kangelase Fantosche'i lõi Prantsusmaal 1909.a. Emile Cohl

  9. Karjas on ohutum elada / Toomas Paul

    Index Scriptorium Estoniae

    Paul, Toomas, 1939-

    2003-01-01

    Vt. ka Paul, Toomas. "Löö esimesena, Freddy!". Eesti Päevaleht, 8. mai 2003. Inimesest kui karjaloomast, inimloomusest ja sallivusest. Ilm. ka: Paul, Toomas. Ole salliv, Bob // Pastishsh & popurrii : ilmavaatlusi / Paul, Toomas. - [Tallinn] : Oomen, 2007. - Lk. 54-58

  10. Kuidas kirjutatakse ajalugu? / Roger Chartier ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Chartier, Roger

    2007-01-01

    Kirjanduslikest tekstidest sotsiaalajaloo uurimisallikana, juhuse ja paratamatuse vahekorrast ajaloos ja Prantsuse revolutsiooni käsitlusest Pariisi õppe- ja teaduskeskuse Ecole des Hautes Etudes en Sciences Sociales professori R. Chartier'i teostes. Varem ilm.: Tekstid, praktikad ja lugejad : intervjuu Roger Chartier'ga // Chartier, Roger. Prantsuse revolutsiooni kultuurilised lätted. - Tallinn, 2002. - Lk. 274-290

  11. Full-Physics Inverse Learning Machine for Satellite Remote Sensing Retrievals

    Science.gov (United States)

    Loyola, D. G.

    2017-12-01

    The satellite remote sensing retrievals are usually ill-posed inverse problems that are typically solved by finding a state vector that minimizes the residual between simulated data and real measurements. The classical inversion methods are very time-consuming as they require iterative calls to complex radiative-transfer forward models to simulate radiances and Jacobians, and subsequent inversion of relatively large matrices. In this work we present a novel and extremely fast algorithm for solving inverse problems called full-physics inverse learning machine (FP-ILM). The FP-ILM algorithm consists of a training phase in which machine learning techniques are used to derive an inversion operator based on synthetic data generated using a radiative transfer model (which expresses the "full-physics" component) and the smart sampling technique, and an operational phase in which the inversion operator is applied to real measurements. FP-ILM has been successfully applied to the retrieval of the SO2 plume height during volcanic eruptions and to the retrieval of ozone profile shapes from UV/VIS satellite sensors. Furthermore, FP-ILM will be used for the near-real-time processing of the upcoming generation of European Sentinel sensors with their unprecedented spectral and spatial resolution and associated large increases in the amount of data.

  12. Kuidas kirjutatakse ajalugu? / Alain Corbin ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Corbin, Alain

    2007-01-01

    Pariis I Ülikooli emeriitprofessori A. Corbini teoste temaatikast ja uurimistöödest. Varem ilm.: Emotsioonid, tunded ja kired : intervjuu Alain Corbiniga // Corbin, Alain. Kannibalide küla : hirm ja raev 19. sajandi Prantsusmaal. - Tallinn, 2000. - Lk. 187-195

  13. Trükis : Kreutzwaldi pildiajakiri

    Index Scriptorium Estoniae

    2003-01-01

    Rahvusraamatukogu esitleb täna F. R. Kreutzwaldi pildiajakirja "Ma-ilm ja mõnda mis seal sees leida on" (1848-1849) faksiimiletrükki; vt. sama ka Postimees, 5. veebr., lk. 27 ja Eesti Päevaleht, 7. veebr., lk. 22

  14. Dicty_cDB: Contig-U05566-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available I(LMS) chicory Cichorium in... 36 1.0 2 ( EL371607 ) CCEL13625.b1_B23.ab1 CCE(LMS) endive Cichorium en... 36...m i... 36 1.0 2 ( EL343029 ) CCEL11023.b1_M20.ab1 CCE(LMS) endive Cichorium en...

  15. Pennimagasinist kopikaajakirjaks: viiekümne puugravüüri mitu elu 1832-1876 / Moonika Teemus

    Index Scriptorium Estoniae

    Teemus, Moonika, 1979-

    2016-01-01

    Inglise pildiajakirja "The Penny Magazine" tekkelugu ja side Eesti lugejaskonnaga. Tartusse jõudnud pennimagasinide puugravüüride uus elu eestikeelse ajakirja "Ma-ilm ja mõnda, mis seal sees leida on" sisu ja kujunduse määramisel. Kirjastaja Heinrich Laakmanni hangitud puugravüüride juurde kirjutas tekstid Fr. R. Kreutzwald

  16. Kontide kasulikkus / Toomas Paul

    Index Scriptorium Estoniae

    Paul, Toomas

    2006-01-01

    Adam, A. Dogmadelugu / Koost. E. Salumaa. Tartu : TÜ Usuteaduskond, 1995 ; H. G. Pöhlmann. Dogmaatika põhijooned / Tlk. E. Salumaa. Tartu : TÜ Usuteaduskond, 1994 ; Karl Barth'i "Kiriklik dogmaatika" / Otto Weberi samanimelise kokkuvõtte alusel koost. ja täiend. E. Salumaa. Tartu : TÜ Usuteaduskond, 1993. Varem ilm.: Akadeemia 1997, nr. 8

  17. A Service Oriented Web Application for Learner Knowledge Representation, Management and Sharing Conforming to IMS LIP

    Science.gov (United States)

    Lazarinis, Fotis

    2014-01-01

    iLM is a Web based application for representation, management and sharing of IMS LIP conformant user profiles. The tool is developed using a service oriented architecture with emphasis on the easy data sharing. Data elicitation from user profiles is based on the utilization of XQuery scripts and sharing with other applications is achieved through…

  18. Vana mees ja kivi: seitse aastat Eesti ema samba saagat / Rein Sikk

    Index Scriptorium Estoniae

    Sikk, Rein, 1961-

    2010-01-01

    26. juunil avatakse Rõuges Eesti Ema monument, mis on 77-aastase Hans Sissase elutöö. 21. juunil olid Moostes kuju viimased lihvijad autorid Ilme ja Riho Kuld. Monumendi püstitamisest Rõuges. Monumendi aluse ja väljaku kavandas arhitekt Peep Jänes

  19. Bengt Gottfried Forselius / Villem Reiman

    Index Scriptorium Estoniae

    Reiman, Villem

    2008-01-01

    Piibli eesti keelde tõlkimisest, eesti kirjakeele arendamisest ja rahvakoolide asutamisest. Forseliuse õpetajate seminarist, õpetajatest, koolimaadest ja -majadest, koolilastest ja kooliõpetusest. Kooli statistika aastast 1688. Varem ilm.: Eesti Üliõpilaste Seltsi Album 1895. Kolmas leht, lk. 7-52

  20. The fine structure of the sperm and spermatid differentiation in the ...

    African Journals Online (AJOL)

    The fine structure of the sperm and spermatid differentiation in the brown mussel Perna perna. RIF. Bernard and A.N. Hodgson. Department of Zoology and Entomology, Rhodes University, Grahamstown. The mature sperm of Perna perna is 50-55 Ilm long and comprises three regions: a head, a mid-piece and a tail. The.

  1. Kuidas kirjutatakse ajalugu? / Jacques Revel ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Revel, Jacques

    2007-01-01

    Prantsuse ajaloolase ja ajakirja Annales ühe peatoimetaja J. Revel'i erialasest tegevusest ja teostest. Varem. ilm.: Sündmused, jutustus ja analüüsiskaalad : intervjuu Jacques Reveliga // Revel, Jacques, Farge, Arlette. Mässu loogika : lasteröövlite afäär Pariisis 1750. - Tallinn, 2005. - Lk. 109-123

  2. Jaan ja Alice Lattik maeti kodumaa mulda / Peep Pillak ; fotod: Peep Pillak

    Index Scriptorium Estoniae

    Pillak, Peep, 1957-

    2008-01-01

    1. novembril 2008 sängitati Viljandi Vanal kalmistul kodumaa mulda tuntud kiriku- ja haridustegelase, kirjaniku, diplomaadi ja poliitiku Jaan Lattiku (1878-1967) ning tema abikaasa Alice'i säilmed. Ümbermatmise tseremoonial Viljandi Pauluse kirikus kõnelesid ka president Toomas Hendrik Ilves ning haridus- ja teadusminister Tõnis Lukas

  3. The results of 25-gauge vitreoretinal surgery for optic disc pit-associated maculopathy: a report of three cases and mini-review of the literature.

    Science.gov (United States)

    Mete, Alper; Türkçüoğlu, Peykan; Kimyon, Sabit; Güngör, Kıvanç

    2017-08-01

    We report the outcomes of three consecutive patients with optic disc pit-associated maculopathy who were treated with 25-gauge pars plana vitrectomy, internal limiting membrane (ILM) peeling, fluid-air exchange, barrage endolaser, and sulfur hexafluoride (SF6) gas tamponade. Patients with optic disc pit-associated maculopathy were treated with 25-gauge pars plana vitrectomy followed by ILM peeling, fluid-air exchange, barrage endolaser, and gas tamponade with 20 % SF6. All patients were asked to maintain a facedown position for 3 days postoperatively. This technique resulted in complete retinal reattachment after 25-gauge vitrectomy, ILM peeling, fluid-air exchange, barrage endolaser, and 20 % SF6 gas injection. The best-corrected visual acuity (BCVA) improved in all three patients and successful anatomical results were achieved. There wasn't any macular detachment in all cases at 20th week follow-up. Our outcomes suggest that 25-gauge vitrectomy with ILM peeling, fluid-air exchange, barrage endolaser, and SF6 gas tamponade appears to be an effective treatment option for optic disc pit-associated maculopathy.

  4. Leo Meyer / Villem Reiman

    Index Scriptorium Estoniae

    Reiman, Villem

    2008-01-01

    Prof. dr. phil. Leo Meyer (03.07.1830-24.05.1910), keeleteadlane, Tartu ja Göttingeni ülikooli ja võrdleva keeleteaduse õppejõud, Eesti Kirjanduse Seltsi kauaaegne esimees ja esimene auliige. Varem ilm.: Eesti Kirjandus, 1910, nr. 9, lk. 389-393

  5. Ajalool on ajaloolaste nägu / Jean-Claude Schmitt ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Schmitt, Jean-Claude

    2004-01-01

    Intervjuu ajaloolase Jean-Claude Schmittiga. Ilm. ka: Keha, pilt ja unenägu : intervjuu Jean-Claude Scmittiga // Schmitt, Jean-Claude. Püha hurdakoer : Guinefort - lasteravija 13. sajandist. - Tallinn, 2000. - Lk. 296-305 ; Kuidas kirjutatakse ajalugu? // Tamm, Marek. Kuidas kirjutatakse ajalugu? - Tallinn, 2007. - 161-177

  6. Narnia - imedemaa riidekapis / Mare Müürsepp

    Index Scriptorium Estoniae

    Müürsepp, Mare

    2006-01-01

    Eestik. ilm.: Lewis, Clive Staples. Lõvi, nõid ja riidekapp ; Prints Caspian ; Imetegija õepoeg ; Hobune ja tema poiss : [jutustused lastele. Tallinn] : Logos, 1995-2000. (Narnia lood). Ka2005.a. USA-s Andrew Adamsoni lavastatud samanimelisest mängufilmist

  7. Diivanil hüppamine lubatud! / Aino Ingrid Sepp

    Index Scriptorium Estoniae

    Sepp, Aino Ingrid

    2008-01-01

    Viietoaline stiilne ja lapsesõbralik korter Tallinna vanalinnas. Sisearhitekt Stina Marttinen, tema kommentaarid. Sisekujundus valmis 2008. aastal. Korterile annavad uue ilme Designers Guildi tekstiilid. Köögimööbli valmistas tellimustööna Eesti firma. 17 värv. vaadet

  8. Rooma impeeriumi surmajärgne elu / Lauri Vahtre

    Index Scriptorium Estoniae

    Vahtre, Lauri, 1960-

    2006-01-01

    200 aastat tagasi (6. aug. 1806) loobus troonist viimane Rooma keiser Franz II, Napoleon purustas Saksa Rahva Püha Rooma riigi. Ilm. ka: Vahtre, Lauri. Ajaloo pööripäevad. 2. - [Tallinn] : Tammerraamat, 2007. Lk. 151-155

  9. Kuidas kirjutatakse ajalugu? / Natalie Zemon Davis ; interv. Marek Tamm

    Index Scriptorium Estoniae

    Davis, Natalie Zemon

    2007-01-01

    Ülevaade Princentoni Ülikooli emeriitprofessori ja Ameerika Ajalooühingu endise presidendi N. Z. Davis'e teostest. Varem ilm.: Ajalugu, filmikunst ja heidikud : intervjuu Natalie Zemon Davisega // Davis, Natalie Zemon. Martin Guerre'i tagasitulek. - Tallinn, 2002. - Lk. 162-177

  10. Meie esimese luuletõlke-antoloogia puhul : [rets.] / Ain Kaalep

    Index Scriptorium Estoniae

    Kaalep, Ain, 1926-

    1997-01-01

    Ilm.: Kirjandus kriitiku pilguga : artikleid, arvustusi ja aastaülevaateid 1975-1976. Tallinn : Eesti Raamat, 1978, lk. 25-31 ; Keel ja Kirjandus 1975, nr. 5, lk. 309-311 . Rets. rmt.: Sang, August. Laenatud laulud I: luuletõlkeid. Tallinn : Eesti Raamat, 1973. 336 lk.; Sang, August. Laenatud laulud II: luuletõlkeid. Tallinn : Eesti Raamat, 1974. 392 lk.

  11. Periodic Solutions of Hamiltonian Systems: A Survey.

    Science.gov (United States)

    1980-12-01

    establishing the existence of periodic solutions of such systems. DD 3 1473 ED.T-ON LF I NOV 11 IS OUSOLETE UNC~ LASSI FIED ,. ec .oy r, i ~ bt lll u I.’ 1 -1.1t PA;- fWho Doe I neo**JI DATE ’ILMED,’

  12. [Internal limiting membrane role in primary surgery of the macular hole].

    Science.gov (United States)

    Brănişteanu, D; Moraru, Andreea

    2013-01-01

    To assess the anatomical result after primary macular hole surgery with or without internal limiting membrane (ILM) peeling. To assess the safety and stability results; Prospective, comparative, interventional case study of 47 eyes with stage 3 or 4 macular hole treated by pars-plana vitrectomy between 2006 and 2011. In 19 cases (40.42%) only posterior hyaloid was removed (control group) while in the other 28 cases (59.57%) additional ILM peeling was performed. All cases had gas endotamponade. Postoperatively the cases were followed-up at least 6 months clinically and by OCT. Statistical analysis was performed using ANOVA and Wilcoxon tests. The mean age of patients in the study was 54, 47 +/- 4, 83 years (ranging from 47 to 74 years). In 36 cases (76.59%) the macular hole was idiopathic. After surgery, the macular hole closed in 22 out of 28 cases with ILM peeling (78.57%) as compared to only 13 out of 19 cases from the control group (68.42%). No intraoperative complications were noted. Main postoperative complications were cataract augmentation and macular hole enlargement in 4 out of 12 failed cases (33.33%). No recurrence was noted if macular hole closed after surgery. These results confirm the stability, safety and efficacy of both techniques but with a significant higher success rate if ILM is peeled. The main postoperative complication was macular hole enlargement if surgery failed.

  13. Tulekul...

    Index Scriptorium Estoniae

    2008-01-01

    Märtsis toimuvatest muusikaüritustest: Tudengijazz 2008, "Matteuse Passioon" kontsertidest, muusikafestivalist Maa ja Ilm, muusikafestivalist Soul Spectrum, harfimängijast Florence Sitruk. Tanel Padari ja ansambli The Sun kontserttuurist. Jazzkaare piletitemüügist. 14. märtsil toimuvast rootsi ansambli Koop kontserdist, rootsi muusikute Mats & Morgan kontsertidest

  14. Euroopa aadel armastab ajalugu / Karin Hallas-Murula

    Index Scriptorium Estoniae

    Hallas-Murula, Karin, 1957-

    2004-01-01

    Organisatsioonist Europa Nostra, mille nõukokku valiti 2003. a. Karin Hallas. Tänavuste Europa Nostra preemiate kätteandmisest Münchenis ja objektidest, mille hulgas oli Leedu endise historitsistliku valitsushoone renoveerimine Kaunases (nüüd ülikooli rektoraat). Uue ilme saanud Tallinna raekoja esitamisest kandidaadiks

  15. Ära pabista, Sam! / Toomas Paul

    Index Scriptorium Estoniae

    Paul, Toomas, 1939-

    2003-01-01

    Inimese võimest leida lohutust täieliku lootusetuse olukorras ja võimetusest ette näha, milliste tulemusteni tema tegevus lõpuks viib. Ilm. ka: Paul, Toomas. Riskiveski krigin // Pastishsh & popurrii : ilmavaatlusi / Paul, Toomas. - [Tallinn] : Oomen, 2007. - Lk. 133-139

  16. Geniaalsus ja hullumeelsus / Ly Ehin

    Index Scriptorium Estoniae

    Seppel, Ly, 1943-

    2005-01-01

    Itaalia psühhiaatri ja kriminoloogi Cesare Lombroso raamatust "Geniaalsus ja hullumeelsus" (ilm. 1864), kus ta väidab, et pärilik hullumeelsus lööb geniaalsetel inimestel sagedamini välja kui kurjategijatel

  17. Inemisest / Jakob Hurt

    Index Scriptorium Estoniae

    Hurt, Jakob, 1839-1907

    2005-01-01

    Ilm.: Tarto Kalender 1868, lk. 21-37 ; Tarto Kalender 1869, lk. 21-32 ; Tarto Kalender 1870, lk. 21-34 ; Tarto Kalender 1873, lk. 41-48 ; J. Hurt. Inemisest. Tartu, 1868 ; J. Hurt. Inemisest. Faksiimiletrükk. Tallinn, 1990

  18. Disseminated sulphides in basalts from the northern central Indian ridge: Implications on late-stage hydrothermal activity

    Digital Repository Service at National Institute of Oceanography (India)

    Banerjee, R.; Ray, D.

    chalcopyrite (Cpy), magnetite (Mgt) and ilmenite (Ilm) are also seen as associated phases Geo-Mar Lett (2015) 35:91–103 93 California, USA, with an ICP-MS finish (Baedecker 1987). For the Ni-sulphide assays, the sample powder (~1 g) was mixed with soda ash...

  19. Moodsad ajad vanas majas : Raekoja 1975. aasta sisekujundus = Modern Times at an Old Building : 1975 Interior Design of Tallinn Town Hall / Kai Lobjakas

    Index Scriptorium Estoniae

    Lobjakas, Kai, 1975-

    2004-01-01

    1973. a. Tallinna Raekojale uue sisekujunduslahenduse saamiseks korraldatud kutsutud konkursi võitis töö Annunciation, mille põhiautoriks oli Leila Pärtelpoeg, kaasautoriteks Aate-Heli Õun, Anu Raud, Ilme-Anu Neemre. Tööd jätkas Leila Pärtelpoeg koos Udo Umbergiga. Rippvaipade galerii autor Valve Ilveste

  20. Tshelovek na katsheljah vremeni : zametki s VIII kinofestivalja "Tjomnõje notshi" / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2004-01-01

    Pimedate Ööde Filmifestivalil nähtud filmidest. Pikemalt Simon Staho filmist "Päev ja öö", Jan Hrebejk' filmist "Üles-alla", Jerzy Stuhl'i filmist "Homne ilm", Guka Omarova "Skiso", Dmitri Meshijevi "Omad" ja Boris Hlebnikovi, Aleksei Popogrebski "Koktebel"

  1. Lomonossovi "Iiobi valitud oodist" / Juri Lotman

    Index Scriptorium Estoniae

    Lotman, Juri, 1922-1993

    2007-01-01

    17.-18. saj. Lääne-Euroopa ja Venemaa ideoloogilisest olukorrast M. Lomonossovi luuletuse "Iiobist valitud ood" alusel. Lisa: Lomonossov, Mihhail. Oda, võbrannaja iz Iovõ. Lk. 119-123. Varem ilm.: Lotman, J. M. Izbrannõje stati v treh tomah, t. II. - Tallinn, 1992. Lk. 29-39

  2. Diamond Deposition and Defect Chemistry Studied via Solid State NMR

    Science.gov (United States)

    1994-06-30

    of the CSA powder patterns are characterized for CF. , hydroxyapatite . 25 groups. Within a certain band of motional narrowing, CF2 and HnchroughNMR e...containedinan epoxy -sealedglas tube. Ilm2. Room tmperature high-speed (15 kHz) MAS "FNMRspetra This Io r ofintensityoffthe highfrequency shoukde featurewould of

  3. Luuleekspordi transpordiprobleeme I-II / Ilmar Laaban

    Index Scriptorium Estoniae

    Laaban, Ilmar, 1921-2000

    1997-01-01

    Varem ilm. Välis-Eesti, 1983, 29. aug. ja 12. okt. Rets. rmt.: Våra sånger fick vi med oss : [Oma laulud tõime endaga kaasa : eesti luule antoloogia] / koost. ja tlk. Silvia Airik-Priuhka. Stockholm : Välis-Eesti ; EMP, 1983

  4. The intubating laryngeal mask produces less heart rate response to ...

    African Journals Online (AJOL)

    Pc

    We compared heart rate and blood pressure changes to intubation produced by conventional laryngoscopic-guided intubation to those produced by blind intubation through the intubating laryngeal mask (ILM) in normotensive adults with normal airways. Forty paralysed, anaesthetised adults undergoing elective surgery ...

  5. Interpretability in PRA

    NARCIS (Netherlands)

    Bílková, M.; de Jongh, D.; Joosten, J.J.

    2009-01-01

    In this paper, we study IL(PRA), the interpretability logic of PRA. As PRA is neither an essentially reflexive theory nor finitely axiomatizable, the two known arithmetical completeness results do not apply to PRA: IL(PRA) is not ILM or ILP. IL(PRA) does, of course, contain all the principles known

  6. Defining adaptive learning design templates for combining design and runtime adaptation in aLFanet

    NARCIS (Netherlands)

    Boticario, Jesús; Santos, Olga; Barrera, Carmen; Gaudioso, Elena; Hernandez, Felix; Rodriguez, Antonio; Van Rosmalen, Peter; Koper, Rob

    2004-01-01

    Adaptive features are expected to improve the effectiveness of the learning process in online learning. Nevertheless, most current adaptive sys-tems do not deal with combining design and runtime adaptations. To take ad-vantage of this combination a new adaptive iLMS based on standards,

  7. Rahuldamata naishingi / Ilmar Laaban

    Index Scriptorium Estoniae

    Laaban, Ilmar, 1921-2000

    1997-01-01

    Varem ilm. Vaba Eesti, 1952, nr. 5. Armastusteema Eesti Kirjanike Kooperatiivi kirjastusel ilmunud romaanides: Mälk, August. Tee kaevule (1952-1953); Thoen, Aino. Igaviku veskid (1952); Helbemäe, Gert. Elamata elu (1952); Õun, Voldemar. Viis paari susse (1952)

  8. "Vesi. Iha. Armastus"

    Index Scriptorium Estoniae

    2005-01-01

    12. aktinäitus "Mees ja Naine" Pärnu Uue Kunsti Muuseumis 29. augustini. Väljapanekul on esindatud: Amandus Adamson, Boaz Tal, Edward Lucie-Smith, Ken Wardrop, Daniel de Chenu, Elina Brotherus, Mark Sadan, Konstantin Tabanakov, Ellen Kolk, Ilme ja Riho Kuld, Hille Palm, Elo Liiv, Hannes Starkopf, Jüri Tenson, Merike Estna, Raili Ilmsalu

  9. Sekretär / Salvatore S. Nigro

    Index Scriptorium Estoniae

    Nigro, Salvatore S.

    2000-01-01

    Hertsog Alfonso II d'Este sekretär Giovan Battista Nicolucci, hüüdnimega Pigna, 1561. a. Veneetsias ilm. sekretäriametnike õpperaamatust "Il Principe". Sekretäri ametinimetuse kujunemisest, töökohustustest ja ametist üldse

  10. Nematoda: Haliplectidae, Suborder Leptolaimina

    African Journals Online (AJOL)

    1991-09-13

    Sep 13, 1991 ... arrow). Anterior lip of anus slightly elevated. Rectum about. 14 ILm long, prerectum not observed. Four pairs of ventrosublateral and five pairs of dorsosublateral pores observed on tail. Spinneret well-defined. Caudal glands three, indistinct. Tail conoid, slightly curved ventrally. R eprod u ced by Sa bin et G.

  11. Postoperative eccentric macular holes after vitrectomy and internal limiting membrane peeling.

    Science.gov (United States)

    Brouzas, Dimitrios; Dettoraki, Maria; Lavaris, Anastasios; Kourvetaris, Dimitrios; Nomikarios, Nikolaos; Moschos, Marilita M

    2017-06-01

    The purpose of this study was to describe the incidence, clinical characteristics, and outcome of eccentric macular holes presenting after vitrectomy and internal limiting membrane (ILM) peeling for the treatment of macular pathology and discuss the pathogenesis of holes formation. A retrospective, noncomparative, interventional case-series study of five patients who developed eccentric macular holes postoperatively following vitrectomy in 198 consecutive patients who underwent ILM peeling for idiopathic macular hole and epiretinal membrane formation between 2008 and 2015. Five patients (2.5 %) developed full-thickness eccentric macular holes postoperatively. Three patients presented with a single eccentric macular hole, one patient had an eccentric hole after a failed idiopathic macular hole surgery and one patient developed four eccentric macular holes. The mean diameter of the holes was 584 μm (range 206-1317 μm) and the average time of holes formation after vitrectomy was 27.7 weeks (range 1-140 weeks). Postoperative best-corrected visual acuity ranged from "counting fingers" to 20/25. The eyes with the holes distant from the fovea had the best final visual acuity. No further intervention was attempted and no complications occurred. The mean follow-up time was 26.8 months. The postoperative macular holes after vitrectomy and ILM peeling were variable in number, size, and time of appearance but remained stable and were not associated with any complications. The pathogenesis of macular holes is most consistent with contraction of the residual ILM or secondary epimacular proliferation probably stimulated by ILM peeling.

  12. [Observation of single-layered inverted internal limiting membrane flap technique for macular hole with retinal detachment in high myopia].

    Science.gov (United States)

    Xu, C Z; Wu, J H; He, J W; Feng, C

    2017-05-11

    Objective: To compare the outcome of pars plana vitrectomy (PPV) with a single-layered inverted internal limiting membrane (ILM) flap versus PPV with ILM peeling for the treatment of macular hole associated retinal detachment (MHRD) in high myopia. Methods: In a retrospective cohort study, PPV with 2 kinds of adjuvant surgical procedures were used in 35 moderately high myopia eyes with MHRD. These eyes were divided into 2 groups: group 1 (17 eyes) receiving PPV and ILM peeling and group 2 (18 eyes) receiving PPV with a single-layered inverted ILM flap. Anatomical reattachment of the retina, macular hole closure, and best-corrected visual acuity (BCVA) were measured at 6 months after surgery. Results: The retina was successfully reattached in all cases. The difference of the retinal reattachment rate between the two groups was not statistically significant (Fisher's exact test, P= 1.000). The rate of macular hole closure was 47.1% in group 1 (8 eyes) and 88.9% in group 2 (16 eyes). The difference of the macular hole closure rate between the two groups was statistically significant (Fisher's exact test, P= 0.012). Significant improvement in logarithm of minimal angle of resolution (logMAR) BCVA was achieved in both groups. There was no difference in the initial, final, or improved logMAR BCVA in the 2 groups. Conclusion: Single-layered inverted ILM flap technique effectively helps close the macular hole in moderately high myopia with MHRD. This may prevent the possible redetachment from the macular hole. (Chin J Ophthalmol, 2017, 53: 338 - 343) .

  13. From hybridization theory to microarray data analysis: performance evaluation

    Directory of Open Access Journals (Sweden)

    Berger Fabrice

    2011-12-01

    Full Text Available Abstract Background Several preprocessing methods are available for the analysis of Affymetrix Genechips arrays. The most popular algorithms analyze the measured fluorescence intensities with statistical methods. Here we focus on a novel algorithm, AffyILM, available from Bioconductor, which relies on inputs from hybridization thermodynamics and uses an extended Langmuir isotherm model to compute transcript concentrations. These concentrations are then employed in the statistical analysis. We compared the performance of AffyILM and other traditional methods both in the old and in the newest generation of GeneChips. Results Tissue mixture and Latin Square datasets (provided by Affymetrix were used to assess the performances of the differential expression analysis depending on the preprocessing strategy. A correlation analysis conducted on the tissue mixture data reveals that the median-polish algorithm allows to best summarize AffyILM concentrations computed at the probe-level. Those correlation results are equivalent to the best correlations observed using popular preprocessing methods relying on intensity values. The performances of each tested preprocessing algorithm were quantified using the Latin Square HG-U133A dataset, thanks to the comparison of differential analysis results with the list of spiked genes. The figures of merit generated illustrates that the performances associated to AffyILM(medianpolish, inferred from the present statistical analysis, are comparable to the best performing strategies previously reported. Conclusions Converting probe intensities to estimates of target concentrations prior to the statistical analysis, AffyILM(medianpolish is one of the best performing strategy currently available. Using hybridization theory, probe-level estimates of target concentrations should be identically distributed. In the future, a probe-level multivariate analysis of the concentrations should be compared to the univariate analysis of

  14. Outcomes of 23-gauge pars plana vitrectomy and internal limiting membrane peeling with brilliant blue in macular hole

    Directory of Open Access Journals (Sweden)

    Nohutcu A

    2011-08-01

    Full Text Available Huseyin Sanisoglu1, Mehmet Sahin Sevim1, Betul Aktas1, Semra Sevim2, Ahmet Nohutcu11Haydarpasa Numune Education and Research Hospital, Department of Ophthalmology, 2Uskudar State Hospital, Eye Clinic, Istanbul, TurkeyPurpose: The evaluation of anatomic and visual outcomes in macular hole cases treated with internal limiting membrane (ILM peeling, brilliant blue (BB, and 23-gauge pars plana vitrectomy (PPV.Materials and methods: Fifty eyes of 48 patients who presented between July 2007 and December 2009 with the diagnosis of stage 2, 3, or 4 macular holes according to Gass Classification who had undergone PPV and ILM peeling were included in this study. Pre- and postoperative macular examinations were assessed with spectral-domain optical coherence tomography. 23 G sutureless PPV and ILM peeling with BB was performed on all patients.Results: The mean age of patients was 63.34 ± 9.6 years. Stage 2 macular hole was determined in 17 eyes (34%, stage 3 in 24 eyes (48%, and stage 4 in 9 eyes (18%. The mean follow-up time was 13.6 ± 1.09 months. Anatomic closure was detected in 46/50 eyes (92%, whereas, in four cases, macular hole persisted and a second operation was not required due to subretinal fluid drainage. At follow-up after 2 months, persistant macular hole was detected in one case and it was closed with reoperation. At 12 months, an increase in visual acuity in 41 eyes was observed, while it remained at the same level in six eyes. In three eyes visual acuity decreased. There was a postoperative statistically significant increase in visual acuity in stage 2 and 3 cases (P < 0.05, however, no increase in visual acuity in stage 4 cases was observed.Conclusion: PPV and ILM peeling in stage 2, 3, and 4 macular hole cases provide successful anatomic outcomes, however, in delayed cases, due to photoreceptor loss, it has no effect on functional recovery. BB, used for clarity of ILM, may be beneficial due to its low retinal toxicity.Keywords: macular

  15. Idiopathic preretinal glia in aging and age-related macular degeneration

    Science.gov (United States)

    Edwards, Malia M.; McLeod, D. Scott; Bhutto, Imran A.; Villalonga, Mercedes B.; Seddon, Johanna M.; Lutty, Gerard A.

    2015-01-01

    During analysis of glia in wholemount aged human retinas, frequent projections onto the vitreal surface of the inner limiting membrane (ILM) were noted. The present study characterized these preretinal glial structures. The amount of glial cells on the vitreal side of the ILM was compared between eyes with age-related macular degeneration (AMD) and age-matched control eyes. Retinal wholemounts were stained for markers of retinal astrocytes and activated Müller cells (glial fibrillary acidic protein, GFAP), Müller cells (vimentin, glutamine synthetase) and microglia/hyalocytes (IBA-1). Retinal vessels were labeled with UEA lectin. Images were collected using a Zeiss 710 confocal microscope. Retinas were then cryopreserved. Laminin labeling of cryosections determined the location of glial structures in relation to the ILM. All retinas investigated herein had varied amounts of preretinal glial. These glial structures were classified into three groups based on size: sprouts, blooms, and membranes. The simplest of the glial structures observed were focal sprouts of singular GFAP-positive cells or processes on the vitreal surface of the ILM. The intermediate structures observed, glial blooms, were created by multiple cells/processes exiting from a single point and extending along the vitreoretinal surface. The most extensive structures, glial membranes, consisted of compact networks of cells and processes. Preretinal glia were observed in all areas of the retina but they were most prominent over large vessels. While all glial blooms and membranes contained vimentin and GFAP-positive cells, these proteins did not always co-localize. Many areas had no preretinal GFAP but had numerous vimentin only glial sprouts. In double labelled glial sprouts, vimentin staining extended beyond that of GFAP. Hyalocytes and microglia were detected along with glial sprouts, blooms, and membranes. They did not, however, concentrate in the retina below these structures. Cross sectional

  16. The ultra-structural organization of the elastic network in the intra- and inter-lamellar matrix of the intervertebral disc.

    Science.gov (United States)

    Tavakoli, J; Elliott, D M; Costi, J J

    2017-08-01

    The inter-lamellar matrix (ILM)-located between adjacent lamellae of the annulus fibrosus-consists of a complex structure of elastic fibers, while elastic fibers of the intra-lamellar region are aligned predominantly parallel to the collagen fibers. The organization of elastic fibers under low magnification, in both inter- and intra-lamellar regions, was studied by light microscopic analysis of histologically prepared samples; however, little is known about their ultrastructure. An ultrastructural visualization of elastic fibers in the inter-lamellar matrix is crucial for describing their contribution to structural integrity, as well as mechanical properties of the annulus fibrosus. The aims of this study were twofold: first, to present an ultrastructural analysis of the elastic fiber network in the ILM and intra-lamellar region, including cross section (CS) and in-plane (IP) lamellae, of the AF using Scanning Electron Microscopy (SEM) and second, to -compare the elastic fiber orientation between the ILM and intra-lamellar region. Four samples (lumbar sheep discs) from adjacent sections (30μm thickness) of anterior annulus were partially digested by a developed NaOH-sonication method for visualization of elastic fibers by SEM. Elastic fiber orientation and distribution were quantified relative to the tangential to circumferential reference axis. Visualization of the ILM under high magnification revealed a dense network of elastic fibers that has not been previously described. Within the ILM, elastic fibers form a complex network, consisting of different size and shape fibers, which differed to those located in the intra-lamellar region. For both regions, the majority of fibers were oriented near 0° with respect to tangential to circumferential (TCD) direction and two minor symmetrical orientations of approximately±45°. Statistically, the orientation of elastic fibers between the ILM and intra-lamellar region was not different (p=0.171). The present study used

  17. Heparan Sulfate Binding Promotes Accumulation of Intravitreally Delivered Adeno-associated Viral Vectors at the Retina for Enhanced Transduction but Weakly Influences Tropism.

    Science.gov (United States)

    Woodard, Kenton T; Liang, Katharine J; Bennett, William C; Samulski, R Jude

    2016-11-01

    Many adeno-associated virus (AAV) serotypes efficiently transduce the retina when delivered to the subretinal space but show limited success when delivered to the vitreous due to the inner limiting membrane (ILM). Subretinal delivery of AAV serotype 2 (AAV2) and its heparan sulfate (HS)-binding-deficient capsid led to similar expression, indicating transduction of the outer retina occurred by HS-independent mechanisms. However, intravitreal delivery of HS-ablated recombinant AAV2 (rAAV2) led to a 300-fold decrease in transduction compared to AAV2. Fluorescence in situ hybridization of AAV transgenes was used to identify differences in retinal trafficking and revealed that HS binding was responsible for AAV2 accumulation at the ILM. This mechanism was tested on human ex vivo retinas and showed similar accumulation with HS-binding AAV2 capsid only. To evaluate if HS binding could be applied to other AAV serotypes to enhance their transduction, AAV1 and AAV8 were modified to bind HS with a single-amino-acid mutation and tested in mice. Both HS-binding mutants of AAV1 and AAV8 had higher intravitreal transduction than their non-HS-binding parent capsid due to increased retinal accumulation. To understand the influence that HS binding has on tropism, chimeric AAV2 capsids with dual-glycan usage were tested intravitreally in mice. Compared to HS binding alone, these chimeric capsids displayed enhanced transduction that was correlated with a change in tropism. Taken together, these data indicate that HS binding serves to sequester AAV capsids from the vitreous to the ILM but does not influence retinal tropism. The enhanced retinal transduction of HS-binding capsids provides a rational design strategy for engineering capsids for intravitreal delivery. Adeno-associated virus (AAV) has become the vector of choice for viral gene transfer and has shown great promise in clinical trials. The need for development of an easy, less invasive injection route for ocular gene therapy

  18. Minéralogie de la fraction argileuse des sols brunifiés de Kahankro ...

    African Journals Online (AJOL)

    ilménite et boéhmite) avec une proportion généralement supérieure à 39%, des minéraux primaires (feldspaths, olivine, dolomite et calcite) ayant une proportion supérieure à 30% et des minéraux argileux (kaolinite, illite et chlorite) qui existent en une proportion généralement inférieure à 25%. Le phénomène d'argilation ...

  19. Uudised : Rubik 3001. Akordionipätid ja muu folk

    Index Scriptorium Estoniae

    2005-01-01

    Koostöös Erkki Tero ja Tristan Priimäega annab artistinime Rubik 3001 kandev Janek Murd 10. märtsil välja esimese singli "Miru mir" mais-juunis ilmuvalt uuelt albumilt (kolme looga singel ilmub värskel Raadio Kosmos netileheküljel www.3pead.com). Aprillis ilmub ka kolme looga singel "My Mind Is Going". Üritusest sarjast MAAjaILM 11. märtsil Tartu Vanemuises

  20. Vaimse koostöö ülesandeid nüüdisajal / Peeter Tarvel

    Index Scriptorium Estoniae

    Tarvel, Peeter

    2002-01-01

    Euroopa rahvaste ja riikide kultuurikoostööst ja kultuurisuhetest alates antiikajast kuni tänapäevani. Fribourgi ülikooli professori G. de Reynold'i ja hollandi kultuuriajaloolase J. Huizinga seisukohad vaimse koostöö osast kaasaegses ühiskonnas, Pariisis 1937. a. peetud vaimse koostöö konverentsil. Varem ilm.: Looming 1938, nr. 5, lk. 553-561

  1. VV. Vabaduse väljak ja demokraatia ruumid = Vabaduse väljak (Freedom Square) and Democratic Spaces / Kalle Komissarov

    Index Scriptorium Estoniae

    Komissarov, Kalle, 1976-

    2007-01-01

    Tallinna Vabaduse väljaku planeeringu autorid: Andres Alver, Tiit Trummal, Veljo Kaasik. Projekteerija: Alver Trummal Arhitektid. Projekt 1999-2006. Makett: Peet Veimer. Vabaduse väljaku uut detailplaneeringut alustati 2000. a. lõpul ning väljak ja lähiala saavad detailplaneeringuga ette nähtud esindusväljakule kohase ilme 2009. a. suve lõpuks

  2. Not all are lost: interrupted laboratory monitoring, early death, and loss to follow-up (LTFU in a large South African treatment program.

    Directory of Open Access Journals (Sweden)

    Aima A Ahonkhai

    Full Text Available Many HIV treatment programs in resource-limited settings are plagued by high rates of loss to follow-up (LTFU. Most studies have not distinguished between those who briefly interrupt, but return to care, and those more chronically lost to follow-up.We conducted a retrospective cohort study of 11,397 adults initiating antiretroviral therapy (ART in 71 Southern African Catholic Bishops Conference/Catholic Relief Services HIV treatment clinics between January 2004 and December 2008. We distinguished among patients with early death, within the first 7 months on ART; patients with interruptions in laboratory monitoring (ILM, defined as missing visits in the first 7 months on ART, but returning to care by 12 months; and those LTFU, defined as missing all follow-up visits in the first 12 months on ART. We used multilevel logistic regression models to determine patient and clinic-level characteristics associated with these outcomes.In the first year on ART, 60% of patients remained in care, 30% missed laboratory visits, and 10% suffered early death. Of the 3,194 patients who missed laboratory visits, 40% had ILM, resuming care by 12 months. After 12 months on ART, patients with ILM had a 30% increase in detectable viremia compared to those who remained in care. Risk of LTFU decreased with increasing enrollment year, and was lowest for patients who enrolled in 2008 compared to 2004 [OR 0.49, 95%CI 0.39-0.62].In a large community-based cohort in South Africa, nearly 30% of patients miss follow-up visits for CD4 monitoring in the first year after starting ART. Of those, 40% have ILM but return to clinic with worse virologic outcomes than those who remain in care. The risk of chronic LTFU decreased with enrollment year. As ART availability increases, interruptions in care may become more common, and should be accounted for in addressing program LTFU.

  3. System for Adaptive Annotation of Hyperlinks in the Conditions of University Courses from the Field of Informatics

    Directory of Open Access Journals (Sweden)

    Turčáni Milan

    2008-10-01

    Full Text Available The main aim of implementing adaptive hypermedia in education is the increase of effectivity of the learning process or the process of acquiring the information related to educational activities. One of the adaptive systems is the system for adaptive annotation of hyperlinks, iLMS. The paper deals with experiences in implementing this system at the Department of Informatics, Faculty of Natural Sciences, Constantine the Philosopher University in Nitra.

  4. "Et ..." : [luuletused] / Kalle Istvan Eller

    Index Scriptorium Estoniae

    Eller, Kalle Istvan, pseud., 1940-

    2002-01-01

    Sisu: "Et ..." ; "päivämõõk lahkse päivä ..." ; "yy kirves lei mant ..." ; kuus om lõhmuse ..." ; "mägi om sattul ..." ; "obetsemägi ..." ; "härtmavitsake ..." ; "Taivast paistus veel ..." ; "soe' lätsi orgo pite ..." ; Pääsoke ; "ilm jääss ütsinda ...". Eluloolisi andmeid autori kohta lk. 366

  5. African Journal of Science and Technology (AJST) L'OR, LE ...

    African Journals Online (AJOL)

    opiyo

    minéraux lourds du profil étudié sont le zircon, les oxydes de fer, l'ilménite, le rutile, la tourmaline. La staurotide, l'anatase sont sous forme de traces. Ces minéraux lourds ont été décrits dans l'environnement géologique proche. (Baras, 1992; Wédraogo et Napon, 1987) dans des granites à biotite et amphibole, des gneiss à ...

  6. Eesti elektrivarustuse võtit hoiab Vene energiakompanii / Tanel Mazur, Risto Berendson

    Index Scriptorium Estoniae

    Mazur, Tanel, 1971-

    2005-01-01

    Ilmunud ka: Narva Postiljon 16. apr., lk. 2, Narvskaja Gazeta 16. apr. lk. 6. Eesti Päevalehes ilm. art. autor ka Risto Berendson. Venemaa firma Lenenergo kontrollib Narva elektrijaamade jahutussüsteemi, kuna hüdroelektrijaama tammist asub Eesti territooriumil vaid pool ja ülejäänu koos tehnorajatistega Venemaal Ivangorodis. Kaart: Narva veehoidla. Lisad: Hüdroelekter; Kasutamata ressurss

  7. Correlation Between En Face Optical Coherence Tomography Defects of the Inner Retinal Layers and Ganglion Cell Inner Plexiform Layer Analysis After Internal Limiting Membrane Peeling for Idiopathic Full-Thickness Macular Hole.

    Science.gov (United States)

    Sabry, Dalia; El-Kannishy, Amr; Kamel, Rania; Abou Samra, Waleed

    2016-07-01

    The purpose of this study was to report en face optical coherence tomography (OCT) inner retinal changes after internal limiting membrane (ILM) peeling for idiopathic full-thickness macular hole (IFTMH) and to correlate these findings with macular ganglion cell inner plexiform layer (GC-IPL) analysis. This prospective study included 20 patients with IFTMH treated using pars plana vitrectomy with ILM peeling. All patients were analyzed using en face OCT at 6 months after surgery to determinate the effect of ILM peeling on the inner retinal layers. Correlation between the GC-IPL en face OCT findings and that obtained by three-dimensional volumetric OCT scanning also was performed. Seven patients (35%) showed defects in the retinal nerve fiber layer (RNFL) that appeared as multiple dark dots with no visible defects at the GC-IPL, either with en face OCT or 3D volumetric OCT scanning. Thirteen patients (65%) showed a similar combination of RNFL defects and well-circumscribed defects in the underlying GC-IPL. These defects could be visualized on en face OCT display, and they correlated with areas of GC-IPL thinning detected in the 3D volumetric OCT scanning. With ILM peeling, en face OCT scanning showed two forms of inner retinal layers changes. The first form was the concentric macular dark spots (CMDS) with intact GC-IPL. The second form appeared in the CMDS with evident localized defects in the underlying GC-IPL. These defects correlate with the areas of GC-IPL thinning detected using 3D volumetric OCT scanning.

  8. Legal Bases for the Use of Force Against International Terrorism: The U.S. Paradigm of Humanitarian Self-Defense

    Science.gov (United States)

    1999-04-01

    See Middle East Press Headlines, AGENCE FRANCE PRESSE, Aug. 22, 1998, at International News, at 1-3: 5 Malaysia has joined other member countries of...sentiment was echoed around the Middle East , where leaders and many citizens roundly criticized Thursday’s American attacks ... Much of the harshest...Deportes et Internes Resistants et Patriotes and Others v. Barbie , 78 Int’l L. Reports 125, 130 (Cass. Crim. 1983). 253 Prosecutor v. Tadic, 35 I.L.M

  9. Kuni 31. VIII on Pärnu uue kunsti muuseumis väljas XI rahvusvaheline aktinäitus "Mees ja naine"

    Index Scriptorium Estoniae

    2004-01-01

    Mark Soosaare kureeritud näitusel osalevad kreeka kunstnikud Nikos Navridis, Michalis Manoussakis ja Nikos Markou, Tšehhi kunstirühmitus Kamera Skura, eesti kunstnikud Lembit Sarapuu, Jaan Toomik, Kaljo Põllu, Ilme ja Riho Kuld. Ateenas Frissirase muuseumis toimub Edward Lucie-Smithi kureeritud aktinäitus "Jumal muutub inimeseks", kus on väljas 11 teost Pärnu Uue Kunsti Muuseumist

  10. FUEL ELEMENTS FOR THERMAL-FISSION NUCLEAR REACTORS

    Science.gov (United States)

    Flint, O.

    1961-01-10

    Fuel elements for thermal-fission nuclear reactors are described. The fuel element is comprised of a core of alumina, a film of a metal of the class consisting of copper, silver, and nickel on the outer face of the core, and a coating of an oxide of a metal isotope of the class consisting of Un/sup 235/, U/ sup 233/, and Pu/sup 239/ on the metal f ilm.

  11. [Social and health impact of Institutes of Legal Medicine in Spain: beyond justice].

    Science.gov (United States)

    Barbería, Eneko; Xifró, Alexandre; Suelves, Josep María; Arimany-Manso, Josep

    2014-03-01

    The main mission of Spanish Institutes of Legal Medicine (ILMs) is to serve the justice system. We review the potential broader role of the work done by ILMs, with an emphasis on forensic pathology. The relevance of forensic information to increase the quality of mortality statistics is highlighted, taking into account the persistence of the low validity of the external causes of death in the Mortality Register that was already detected more than a decade ago. The new statistical form and reporting system for the deaths under ILMs jurisdiction, as introduced by the Spanish Instituto Nacional de Estadística in 2009, are also described. The IMLs role in the investigation of the following mortality causes and of their determinants is reviewed in detail: traffic accidents, suicide, drugs of abuse, child deaths and sudden deaths. We conclude that an important public role of IMLs is emerging beyond their valuable service to the justice system, mainly through the gathering of data critical to assess and prevent several medical and public health and safety issues of great social impact and through their participation in epidemiologic research and surveillance. Copyright © 2014 Elsevier España, S.L. All rights reserved.

  12. Utility of microscope-integrated optical coherence tomography (MIOCT) in the treatment of myopic macular hole retinal detachment.

    Science.gov (United States)

    Kumar, Atul; Kakkar, Prateek; Ravani, Raghav Dinesh; Markan, Ashish

    2017-07-14

    Macular hole-associated retinal detachment in high myopia is described as a final stage in progression of myopic traction maculopathy (MTM). 1â€"3 Shimada et al 4 described the progressive stages of MTM from macular retinoschisis to serous retinal detachment in high myopia. Stage 4 MTM is characterised as disappearance of retinoschisis with progression to retinal detachment due to macular hole formation. It is hypothesised that vitreoschisis and abnormal vitreo-retinal interface create the premacular tangential traction. 5 6 Intraoperative triamcinolone acetonide is used to visualise the residual posterior vitreous cortex (PVC). We hereby describe the utility of microscope-integrated optical coherence tomography (MIOCT) in assisting complete removal of PVC and internal limiting membrane (ILM) peeling with multilayered inverted ILM flap in the treatment of myopic macular hole retinal detachment. MIOCT helped identify vitreoschisis and confirm the position of ILM flaps over the macular hole intraoperatively. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  13. Outcomes of microscope-integrated intraoperative optical coherence tomography-guided center-sparing internal limiting membrane peeling for myopic traction maculopathy: a novel technique.

    Science.gov (United States)

    Kumar, Atul; Ravani, Raghav; Mehta, Aditi; Simakurthy, Sriram; Dhull, Chirakshi

    2017-07-04

    To evaluate the outcomes of pars plana vitrectomy (PPV) with microscope-integrated intraoperative optical coherence tomography (I-OCT)-guided traction removal and center-sparing internal limiting membrane (cs-ILM) peeling. Nine eyes with myopic traction maculopathy as diagnosed on SD-OCT underwent PPV with I-OCT-guided cs-ILM peeling and were evaluated prospectively for resolution of central macular thickness (CMT) and improvement in best-corrected visual acuity (BCVA), and complications, if any, were noted. All patients were followed up for more than 9 months. Resolution of the macular retinoschisis was seen in all nine eyes on SD-OCT. At 36 weeks, there was a significant improvement in mean BCVA from the preoperative BCVA (P = 0.0089) along with a reduction in the CMT from 569.77 ± 263.19 to 166.0 ± 43.91 um (P = 0.0039). None of the eyes showed worsening of BCVA or development of full-thickness macular hole in the intraoperative or follow-up period. PPV with I-OCT-guided cs-ILM peeling helps in complete removal of traction, resolution of retinoschisis and good functional recovery with low intraoperative and postoperative complications.

  14. HABA-based ionic liquid matrices for UV-MALDI-MS analysis of heparin and heparan sulfate oligosaccharides.

    Science.gov (United States)

    Przybylski, Cedric; Gonnet, Florence; Bonnaffé, David; Hersant, Yael; Lortat-Jacob, Hugues; Daniel, Regis

    2010-02-01

    Polysulfated carbohydrates such as heparin (HP) and heparan sulfate (HS) are not easily amenable to usual ultraviolet matrix-assisted laser desorption/ionization-mass spectrometry (UV-MALDI)-MS analysis due to the thermal lability of their O- and N-SO(3) moieties, and their poor ionization efficiency with common crystalline matrices. Recently, ionic liquid matrices showed considerable advantages over conventional matrices for MALDI-MS of acidic compounds. Two new ionic liquid matrices (ILMs) based on the combination of 2-(4-hydroxyphenylazo)benzoic acid (HABA) with 1,1,3,3-tetramethylguanidine and spermine were evaluated in the study herein. Both ILMs were successfully applied to the analysis of synthetic heparin oligosaccharides of well-characterized structures as well as to heparan sulfate-derived oligosaccharides from enzymatic depolymerization. HABA-based ILMs showed improved signal-to-noise ratio as well as a decrease of fragmentation/desulfation processes and cation exchange. Sulfated oligosaccharides were detected with higher sensitivity than usual crystalline matrices, and their intact fully O- and N-sulfated species [M-Na](-) were easily observed on mass spectra. MALDI-MS characterization of challenging analytes such as heparin octasaccharide carrying 8-O and 4 N-sulfo groups, and heparin octadecasulfated dodecasaccharide was successfully achieved.

  15. Lama1 mutations lead to vitreoretinal blood vessel formation, persistence of fetal vasculature, and epiretinal membrane formation in mice

    Directory of Open Access Journals (Sweden)

    Heng Céline

    2011-10-01

    Full Text Available Abstract Background Valuable insights into the complex process of retinal vascular development can be gained using models with abnormal retinal vasculature. Two such models are the recently described mouse lines with mutations in Lama1, an important component of the retinal internal limiting membrane (ILM. These mutants have a persistence of the fetal vasculature of vitreous (FVV but lack a primary retinal vascular plexus. The present study provides a detailed analysis of astrocyte and vascular development in these Lama1 mutants. Results Although astrocytes and blood vessels initially migrate into Lama1 mutant retinas, both traverse the peripapillary ILM into the vitreous by P3. Once in the vitreous, blood vessels anastomose with vessels of the vasa hyaloidea propria, part of the FVV, and eventually re-enter the retina where they dive to form the inner and outer retinal capillary networks. Astrocytes continue proliferating within the vitreous to form a dense mesh that resembles epiretinal membranes associated with persistent fetal vasculature and proliferative vitreoretinopathy. Conclusions Lama1 and a fully intact ILM are required for normal retinal vascular development. Mutations in Lama1 allow developing retinal vessels to enter the vitreous where they anastomose with vessels of the hyaloid system which persist and expand. Together, these vessels branch into the retina to form fairly normal inner retinal vascular capillary plexi. The Lama1 mutants described in this report are potential models for studying the human conditions persistent fetal vasculature and proliferative vitreoretinopathy.

  16. Solving a Novel Inventory Location Model with Stochastic Constraints and (R,s,S Inventory Control Policy

    Directory of Open Access Journals (Sweden)

    Guillermo Cabrera

    2013-01-01

    Full Text Available We solve a novel inventory-location model with a stochastic capacity constraint based on a periodic inventory control (ILM-PR policy. The ILM-PR policy implies several changes with regard to other previous models proposed in the literature, which consider continuous review as their inventory policy. One of these changes is the inclusion of the undershoot concept, which has not been considered in previous ILM models in the literature. Based on our model, we are able to design a distribution network for a two-level supply chain, addressing both warehouse location and customer assignment decisions, whilst taking into consideration several aspects of inventory planning, in particular, evaluating the impact of the inventory control review period on the network configuration and system costs. Because the model is a very hard-to solve combinatorial nonlinear optimisation problem, we implemented two heuristics to solve it, namely, Tabu Search and Particle Swarm Optimisation. These approaches were tested over small instances in which they were able to find the optimal solution in just a few seconds. Because the model is a new one, a set of medium-size instances is provided that can be useful as a benchmark in future research. The heuristics showed a good convergence rate when applied to those instances. The results confirm that decision making over the inventory control policy has effects on the distribution network design.

  17. Displacement of fovea toward optic disk after macular hole surgery with internal limiting membrane peeling

    Directory of Open Access Journals (Sweden)

    Ohta K

    2017-10-01

    Full Text Available Kouichi Ohta, Atsuko Sato, Nami Senda, Emi Fukui Department of Ophthalmology, Matsumoto Dental University, Shiojiri, Nagano, Japan Purpose: The purpose of this study was to demonstrate a displacement of the foveal depression toward the optic disk after idiopathic macular hole (MH surgery with internal limiting membrane (ILM peeling.Methods: Two patients with a unilateral MH developed an MH in the fellow eyes. Vitrectomy with ILM peeling was performed on the fellow eye to close the MH. Images of spectral-domain optical coherence tomography (SD-OCT were used to measure the disk-to-fovea distances pre MH formation, after MH formation, and 6 months after the closure of the MH.Results: The disk-to-fovea distance was shorter at 6 months than after the development of the MH (4,109 µm and 4,174 µm in Case 1 and 4,001 µm and 4,051 µm in Case 2.Conclusion: These results indicate that the fovea moves nasally after the MH surgery with ILM peeling. Keywords: idiopathic macular hole, internal limiting membrane, optical coherence tomography, pars plana vitrectomy

  18. Macular hole surgery: an analysis of risk factors for the anatomical and functional outcomes with a special emphasis on the experience of the surgeon

    Directory of Open Access Journals (Sweden)

    Jenisch TM

    2017-06-01

    Full Text Available Teresa M Jenisch,1 Florian Zeman,2 Michael Koller,2 David A Märker,1 Horst Helbig,1 Wolfgang A Herrmann1,3 1Department of Ophthalmology, 2Centre for Clinical Studies, University Hospital Regensburg, 3Department of Ophthalmology, St John of God Hospital, Regensburg, Germany Purpose: The aim of this study was to evaluate risk factors for the anatomical and functional outcomes of macular hole (MH surgery with special emphasis on the experience of the surgeon. Methods: A total of 225 surgeries on idiopathic MHs (IMHs performed by 6 surgeons with a mean follow-up period of 20.5 months were reviewed in this retrospective study. Outcome parameters focused on IMH closure, complications and visual acuity improvement. The results of MH surgeries performed by experienced surgeons were compared to those of surgeons in training. Results: The average MH size was 381 µm (standard deviation [SD]=168. Brilliant blue G (BBG for internal limiting membrane (ILM staining was used in 109 (48% eyes and indocyanine green (ICG in 116 (52% eyes. As endotamponade, 20% SF6 was used in 38 (17% cases, 16% C2F6 in 33 (15% cases and 16% C3F8 in 154 (68% cases. IMH closure was achieved in 194 eyes (86%. Mean preoperative visual acuity was 0.84 logarithm of the minimum angle of resolution (log MAR; SD=0.29, range: 0.3–1.5; surgery led to a mean improvement of 0.40 (SD=0.37 log MAR. Although the MH closure rate was the same using BBG or ICG for ILM peeling, visual acuity improvement was better in eyes peeled with BBG compared to eyes peeled with ICG (log MAR: BBG: 0.38 [95% CI: 0.32, 0.44] vs ICG: 0.48 [95% CI: 0.42, 0.54], P=0.029. Surgeons with previous experience in vitreoretinal surgery of ≥6 years achieved better visual outcomes compared to surgeons with 0–3 years of experience, regardless of the MH size, preoperative visual acuity, time to follow-up or dye used for ILM peeling (0–3 years [0.27, ∆log MAR] vs ≥6 years [0.43, ∆log MAR], P=0.009. Conclusion

  19. The Integrated Landscape Modeling partnership - Current status and future directions

    Science.gov (United States)

    Mushet, David M.; Scherff, Eric J.

    2016-01-28

    The Integrated Landscape Modeling (ILM) partnership is an effort by the U.S. Geological Survey (USGS) and U.S. Department of Agriculture (USDA) to identify, evaluate, and develop models to quantify services derived from ecosystems, with a focus on wetland ecosystems and conservation effects. The ILM partnership uses the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST) modeling platform to facilitate regional quantifications of ecosystem services under various scenarios of land-cover change that are representative of differing conservation program and practice implementation scenarios. To date, the ILM InVEST partnership has resulted in capabilities to quantify carbon stores, amphibian habitat, plant-community diversity, and pollination services. Work to include waterfowl and grassland bird habitat quality is in progress. Initial InVEST modeling has been focused on the Prairie Pothole Region (PPR) of the United States; future efforts might encompass other regions as data availability and knowledge increase as to how functions affecting ecosystem services differ among regions.The ILM partnership is also developing the capability for field-scale process-based modeling of depressional wetland ecosystems using the Agricultural Policy/Environmental Extender (APEX) model. Progress was made towards the development of techniques to use the APEX model for closed-basin depressional wetlands of the PPR, in addition to the open systems that the model was originally designed to simulate. The ILM partnership has matured to the stage where effects of conservation programs and practices on multiple ecosystem services can now be simulated in selected areas. Future work might include the continued development of modeling capabilities, as well as development and evaluation of differing conservation program and practice scenarios of interest to partner agencies including the USDA’s Farm Service Agency (FSA) and Natural Resources Conservation Service (NRCS). When

  20. METASOMATIC AND MAGMATIC PROCESSES IN THE MANTLE LITHOSPHERE OF THE BIREKTE TERRAIN OF THE SIBERIAN CRATON AND THEIR EFFECT ON THE LITHOSPHERE EVOLUTION

    Directory of Open Access Journals (Sweden)

    Lidia V. Solov’eva

    2015-01-01

    Full Text Available The area of studies covers the north-eastern part of the Siberian craton (the Birekte terrain, Russia. The influence of metasomatic and magmatic processes on the mantle lithosphere is studied based on results of analyses of phlogopite- and phlogopite-amphibole-containing deep-seated xenoliths from kimberlites of the Kuoika field. In the kimberlitic pipes, deep-seated xenoliths with mantle phlogopite- and phlogopite-amphibole mineralization are developed in two genetically different rock series: magnesian (Mg pyroxenite-peridotite series (with magnesian composition of rocks and minerals and phlogopite-ilmenite (Phl-Ilm hyperbasite series (with ferrous types of rocks and minerals. This paper is focused on issues of petrography and mineralogy of the xenoliths and describes the evidence of metasomatic / magmatic genesis of phlogopite and amphibole. We report here the first data set of 40Ar/39Ar age determinations for phlogopite from the rocks of the magnesian pyroxenite-peridotite series and the ferrous Phl-Ilm hyperbasite series.The Mg series is represented by a continuous transition of rocks from Sp, Sp-Grt, Grt clinopyroxenite and ortopyroxenite to websterite and lherzolite. Many researchers consider it as a layered intrusion in the mantle [Ukhanov et al., 1988; Solov’eva et al., 1994]. The mantle metasomatic phlogopite and amphibole are revealed in all petrographic types of the rocks in this series and compose transverse veins and irregular patchs at grain boundaries of primary minerals. At contacts of xenolith and its host kimberlite, grains of phlogopite and amphibole are often cut off, which gives an evidence of the development of metasomatic phlogopite-amphibole mineralization in the rocks before its’ entraiment into the kimberlite. In the xenoliths with exsolution pyroxene megacrystalls, comprising parallel plates of clino- and orthopyroxene ± garnet ± spinel (former high-temperature pigeonite [Solov’eva et al., 1994], the

  1. Single night postoperative prone posturing in idiopathic macular hole surgery.

    LENUS (Irish Health Repository)

    2012-02-01

    Purpose. To evaluate the role of postoperative prone posturing for a single night in the outcome of trans pars plana vitrectomy (TPPV) with internal limiting membrane (ILM) peel and 20% perfluoroethane (C2F6) internal tamponade for idiopathic macular hole. Methods. This prospective trial enrolled 14 eyes in 14 consecutive patients with idiopathic macular hole. All eyes underwent TPPV with vision blue assisted ILM peeling with and without phacoemulsification and intraocular lens (IOL) for macular hole. Intraocular gas tamponade (20% C2F6) was used in all cases with postoperative face-down posturing overnight and without specific posturing afterwards. LogMAR visual acuity, appearance by slit-lamp biomicroscopy, and ocular coherence tomography (OCT) scans were compared preoperatively and postoperatively to assess outcome. Results. Among 14 eyes recruited, all eyes were phakic; 50% of patients underwent concurrent phacoemulsification with IOL. The macular holes were categorized preoperatively by OCT appearance, 4 (28.57%) were stage 2, 7 (50%) were stage 3, and 3 (21.43%) were stage 4. Mean macular hole size was 0.35 disk diameters. Symptoms of macular hole had been present for an average of 6.5 months. All holes (100%) were closed 3 and 6 months postoperatively. Mean visual acuity (logMAR) was improved to 0.61 at 3 months and was stable at 6 months after the surgery. None of the eyes had worse vision postoperatively. Conclusions. Vitrectomy with ILM peeling and 20% C2F6 gas with a brief postoperative 1 night prone posturing regimen is a reasonable approach to achieve anatomic closure in idiopathic macular hole. Concurrent cataract extraction did not alter outcomes and was not associated with any additional complications.

  2. Immunocytochemical and ultrastructural evidence of glial cells and hyalocytes in internal limiting membrane specimens of idiopathic macular holes.

    Science.gov (United States)

    Schumann, Ricarda G; Eibl, Kirsten H; Zhao, Fei; Scheerbaum, Martin; Scheler, Renate; Schaumberger, Markus M; Wehnes, Helga; Walch, Axel K; Haritoglou, Christos; Kampik, Anselm; Gandorfer, Arnd

    2011-10-03

    To provide new information on epiretinal cell proliferation and the cells' origin in idiopathic macular holes and to overcome the effects of embedding and sectioning preparation procedures on cell-distribution patterns. Interference and phase-contrast microscopy, immunocytochemistry, and scanning and transmission electron microscopy were performed on surgically excised whole-mounted internal limiting membrane (ILM) specimens removed from 60 eyes with idiopathic macular holes. Cell distribution and cell morphology were correlated with immunocytochemical staining characteristics. Twelve cell type-specific antibodies were used to detect glial cells, hyalocytes, retinal pigment epithelial cells, retinal ganglion cells, and immune cells. Cell viability was analyzed. Epiretinal cell proliferation was found in all ILM specimens, irrespective of the stage of the macular hole. Cell density showed a broad variety. Immunocytochemistry frequently revealed simultaneous expression of GFAP/CD45, GFAP/CD64, GFAP/CD68, GFAP/CRALBP, and GFAP/CD90. Some cells presented with intracellular contractile filaments (anti-αSMA); others were not immunoreactive to any antibody examined. The percentage of viable cells showed a broad variety with a mean of 73% (SD 29%). Electron microscopy demonstrated glial cells, hyalocytes, and myofibroblast-like cells. The presence of epiretinal cells at the ILM in all macular hole stages strongly suggests a substantial involvement of cell migration and proliferation in the course of macular hole development. Glial cells and hyalocytes play the predominant role in epiretinal cell proliferation. Given the co-expression of glial cell and hyalocyte markers, transdifferentiation of epiretinal cells needs further elucidation, especially with respect to αSMA-positive cells leading to traction at the vitreoretinal interface.

  3. Risk of mental health and nutritional problems for left-behind children of international labor migrants.

    Science.gov (United States)

    Wickramage, Kolitha; Siriwardhana, Chesmal; Vidanapathirana, Puwalani; Weerawarna, Sulochana; Jayasekara, Buddhini; Pannala, Gayani; Adikari, Anushka; Jayaweera, Kaushalya; Peiris, Sharika; Siribaddana, Sisira; Sumathipala, Athula

    2015-03-06

    One-in-ten Sri Lankans are employed abroad as International Labor Migrants (ILM), mainly as domestic maids or low-skilled laborers. Little is known about the impact their migration has on the health status of the children they 'leave behind'. This national study explored associations between the health status of 'left-behind' children of ILM's with those from comparative non-migrant families. A cross-sectional study design with multi-stage random sampling was used to survey a total of 820 children matched for both age and sex. Socio-demographic and health status data were derived using standardized pre-validated instruments. Univariate and multivariate analyses were used to estimate the differences in mental health outcomes between children of migrant vs. non-migrant families. Two in every five left-behind children were shown to have mental disorders [95%CI: 37.4-49.2, p mental health status were observed. Over a quarter (30%) of the left-behind children aged 6-59 months were 'underweight or severely underweight' compared to 17.7% of non-migrant children. Findings provide evidence on health consequences for children of migrant worker families in a country experiencing heavy out-migration of labour, where remittances from ILM's remain as the single highest contributor to the economy. These findings may be relevant for other labour 'sending countries' in Asia relying on contractual labor migration for economic gain. Further studies are needed to assess longitudinal health impacts on the children left-behind.

  4. The art and science of digital compositing techniques for visual effects, animation and motion graphics

    CERN Document Server

    Brinkmann, Ron

    2008-01-01

    *The classic reference, with over 25,000 copies in print, has been massively expanded and thoroughly updated to include state-of-the-art methods and 400+ all-new full color images!At ILM, compositing is one of the most important tools we use. If you want to learn more, this excellent 2nd-edition is detailed with hundreds of secrets that will help make your comps seamless. For beginners or experts, Ron walks you through the processes of analysis and workflows - linear thinking which will help you become deft and successfully tackle any shot. - Dennis Muren ASC, Senior Visual Effects Supervisor,

  5. Leadership Development in the Civilian Work Force

    Science.gov (United States)

    1984-05-17

    Lead Other), Firo - B , a values exercise, and the Myers Briggs Type Indicator (MBTI) as methods for getting in touch with personal leader- ship...lhe vim Iprns b Owadl dom a"n~ 14 =h 7=42146"t am o • de ame mmua y fw o. rwhu oT1 is tm rn Ilme h ahai , Spur pulualk, .66il docahoi my we be ehd 1h...leaders, and a system for nurturing and sustaining quality leadership throug a proactive approach to the Department’s personnel management progr m

  6. Vitrectomy with Internal Limiting Membrane Peeling versus No Peeling for Idiopathic Full-Thickness Macular Hole

    DEFF Research Database (Denmark)

    Spiteri Cornish, Kurt; Lois, Noemi; Scott, Neil W

    2014-01-01

    under the auspices of the Cochrane Eyes and Vision Group. Only randomized controlled trials (RCTs) were included. PARTICIPANTS AND CONTROLS: Patients with idiopathic stage 2, 3, and 4 FTMH undergoing vitrectomy with or without ILM peeling. INTERVENTION: Macular hole surgery, including vitrectomy and gas......) and final (after >1 surgery) macular hole closure; need for additional surgical interventions; intraoperative and postoperative complications; patient-reported outcomes (PROs) (EuroQol-5D and Vision Function Questionnaire-25 scores at 6 months); and cost-effectiveness. RESULTS: Four RCTs were identified...

  7. Macular morphology and visual acuity after macular hole surgery with or without internal limiting membrane peeling

    DEFF Research Database (Denmark)

    Christensen, U.C.; Kroyer, K.; Sander, B.

    2010-01-01

    Aim: To examine postoperative macular morphology and visual outcome after 12 months in relation to internal limiting membrane (ILM) peeling versus no peeling, indocyanine green (ICG) staining and re-operation in eyes that achieved macular hole closure after surgery. Methods: Seventy-four eyes...... tomography was used to assess central foveal thickness, central photoreceptor layer thickness (CPRT), central photoreceptor layer discontinuity (PRD) and relative reflectivity of the outer nuclear layer. Outcomes were correlated with best corrected visual acuity (BCVA) 12 months after surgery. Results: BCVA...

  8. Prognostic significance of delayed structural recovery after macular hole surgery

    DEFF Research Database (Denmark)

    Christensen, Ulrik C; Krøyer, Kristian; Sander, Birgit

    2009-01-01

    clinical trial. PARTICIPANTS: Participants were recruited from a randomized clinical trial evaluating internal limiting membrane (ILM) peeling in macular hole surgery. The study included 74 eyes in which a contiguous retinal surface or a full attachment with a flat neuroretinal rim had been reestablished...... after 12 months compared with eyes with a fully attached fovea at 3 months (70.9 letters vs. 72.0 letters; P = 0.59). Receiver operating characteristics curve analysis identified persistent photoreceptor layer discontinuity of a diameter of more than 1477 microm after 3 months to be associated...

  9. Milliseid erialaseid teadmisi ja oskusi olete kasutanud oma praeguses ametis? : vastavad infoteaduse eriala vilistlased / interv. Hela Ojasaar, Margot Mahlapuu

    Index Scriptorium Estoniae

    2005-01-01

    Vastavad: EV Presidendi Kantselei direktori asetäitja, üldosakonna juhataja Riina Roomet, Mahtra Talurahvamuuseumi direktor Tiia-Helle Schmitte, EBS-i raamatukogu juhataja Eda Pihu, Euroopa Liidu asjade komisjoni nõunik (Riigikogu) Külli Kask, Kultuuriministeeriumi raamatukogunõunik Meeli Veskus, Võrumaa Keskraamatukogu direktor Inga Kuljus, Lääne Maakonna Keskraamatukogu direktor Ilme Sepp, Riigiarhiivi direktor Marge Tiidus, kirjastuse Pilgrim juht Tiina Ristimets, Tallinna Keskraamatukogu direktor Kaie Holm, Eesti ENIC/NARIC Keskuse infospetsialist Liia Tüür, Eesti Rahvusraamatukogu direktor Tiiu Valm, Tartu Ülikooli Raamatukogu teenindusdirektor Mare-Nelli Ilus, Viljandi Kultuuriakadeemia raamatukogunduse ja infoteaduste osakonna juhataja Ilmar Vaaro

  10. Atomic layer deposition of Cu( i ) oxide films using Cu( ii ) bis(dimethylamino-2-propoxide) and water

    Energy Technology Data Exchange (ETDEWEB)

    Avila, J. R.; Peters, A. W.; Li, Zhanyong; Ortuño, M. A.; Martinson, A. B. F.; Cramer, C. J.; Hupp, J. T.; Farha, O. K.

    2017-01-01

    To grow fIlms of Cu2O, bis-(dimethylamino-2-propoxide)Cu(II), or Cu(dmap), is used as an atomic layer deposition precursor using only water vapor as a co-reactant. Between 110 and 175 °C, a growth rate of 0.12 ± 0.02 Å per cycle was measured using an in situ quartz crystal microbalance (QCM). X-ray photoelectron spectroscopy (XPS) confirms the growth of metal– oxide films featuring Cu(I).

  11. Muusika : Stephan Oliva kvartett Eestis. Yamaha stipendium Hando Nahkurile. Eespere neljas autoriplaat. Uus rahvamuusikafestival. Uus orel uude kirikusse! Valga klaveriansamblite festival. Rahvusooperi poistekoor kutsub / Marje Laugen

    Index Scriptorium Estoniae

    Laugen, Marje

    2002-01-01

    Prantsuse dzhässpianist Stephan Oliva annab oma kvartetiga Eestis 6 kontserti. Yamaha konkursi stipendiumi võitis EMA I kursuse klaveri eriala üliõpilane Hando Nahkur. Rene Eespere neljanda autoriplaadi "Skulptuuri hommik" esitletakse EMA suures kammersaalis. 7.-9. märtsini saavad Tartus ja Tallinnas teoks muusikapäevad "MAA ja ILM". Kontserdisarjas "Orel kirikusse!" teeb järjekordse panuse Tallinna Metodisti kiriku oreli heaks Raekoja kammerkoor oma kontserdiga. 16. ja 17. veebr. Valga muusikakoolis toimunud VII rahvusvahelisest laste- ja noorte klaveriansamblite festivalist. Rahvusooperi poistekoor kutsub oma ridadesse uusi lauljaid

  12. 12. VI avati Pärnu uue kunsti muuseumis...

    Index Scriptorium Estoniae

    2005-01-01

    XII aktinäitus "Mees ja naine" alapealkirjaga "Vesi. Iha. Armastus". Väljas on Amandus Adamsoni 150. sünniaastapäeva puhul tema kaks teost. Konkursilt valis žürii Elo Liivi, Hannes Starkopfi, Ellen Kolgi, Ilme ja Riho Kulla kavandid, mille järgi skulptorid teevad sügiseks Carrara marmorist kujud. Vaadata on Hille Palmi ja Ellen Kolgi marmortööd, Raili Ilmsalu diplomitöö "Eva", Boaz Tali aktifotod, Mark Sadani Eeva-tõlgendused, Daniel de Chenu ja Elina Brotheruse videod, Ken Wardropi lühifilm "Undressing My Mother", Edward Lucie-Smithi fotod

  13. Mined-out land

    International Nuclear Information System (INIS)

    Reinsalu, Enno; Toomik, Arvi; Valgma, Ingo

    2002-01-01

    Estonian mineral resources are deposited in low depth and mining fields are large, therefore vast areas are affected by mining. There are at least 800 deposits with total area of 6,000 km 2 and about the same number of underground mines, surface mines, peat fields, quarries, and sand and gravel pits. The deposits cover more than 10% of Estonian mainland. The total area of operating mine claims exceeds 150 km 2 that makes 0.3 % of Estonian area. The book is written mainly for the people who are living or acting in the area influenced by mining. The observations and research could benefit those who are interested in geography and environment, who follow formation and look of mined-out landscapes. The book contains also warnings for careless people on and under the surface of the mined-out land. Part of the book contains results of the research made in 1968-1993 by the first two authors working at the Estonian branch of A.Skochinsky Institute of Mining. Since 1990, Arvi Toomik continued this study at the Northeastern section of the Institute of Ecology of Tallinn Pedagogical University. Enno Reinsalu studied aftereffects of mining at the Mining Department of Tallinn Technical University from 1998 to 2000. Geographical Information System for Mining was studied by Ingo Valgma within his doctoral dissertation, and this book is one of the applications of his study

  14. Places with Prime Contract Awards of $5 Million or More, Fiscal Year 1987.

    Science.gov (United States)

    1987-01-01

    11.1 X:L4 4002W XɜW401-0 In o Ga 𔃺 .1 Z"-~-u 44 -1 Zwowl-0 cc0 j <.C 44 Z0 4 - IZ4 -4c V0 1 W"O.-40Z1.-01- www蓑---" -- 44- www4001-O"- wal-0zl-- C...nnt _ L- tD N .M 0 -M - - - - - - - - - -- - - - - - - N (4) -4 4 4 r, En 0 0 ooco4t-.41 00000 000000 014N40 -400-4 v momC 1-MQ4 0 0 4 0 44400 En~nO N N...1:lj..4W X -Oxw 0 m1W WUII-Z WU)-Oxw n 0 0 40 a - zw-jɜ-uL វ -4 0’- -L (z I--Li .. Jz"-LiXI- .- iZ4 -44-Li ac fA Li 10 W"ɘ-4L0-"QoLi"- a.ww4-4U) i

  15. Ultrastructural and histopathologic findings after pars plana vitrectomy with a new hypersonic vitrector system. Qualitative preliminary assessment.

    Directory of Open Access Journals (Sweden)

    Salvador Pastor-Idoate

    Full Text Available Preliminary assessment of a new prototype ultrasound-based hypersonic vitrector (HV by qualitatively examining the histopathological changes in the retina and vitreous body after pars plana vitrectomy (PPV and its ability to fragment vitreous collagen.Fourteen porcine cadaveric eyes, 20 eyes in live swine and six human cadaveric eyes underwent PPV using the HV or a pneumatic guillotine vitrector (GV. An additional 4 porcine crystalline lenses were touched with either the HV or GV for 1 minute. Following PPV, human vitreous was removed and processed for electron microscopy (EM. Eyes and lenses were fixed and sectioned for light microscopy (LM.There were no macroscopic retinal or optic nerve defects associated with either HV or GV PPVs. Cadaveric retinal specimens showed separation of the inner limiting membrane (ILM and vacuolization and fragmentation at the nerve fiber layer (NFL and the ganglion cell layer (GCL. ILM fragmentation and separation were found after PPV in live swine with both vitrectors. Small disruptions of the posterior capsule or structural lens defects were found after HV touch. The EM analysis revealed more fragmentation of human vitreous collagen fibrils after HV compared to GV PPV.LM and EM analysis of retina, vitreous, and crystalline lens after PPV showed similar morphological changes using the HV or the GV. Vitreous fragmentation appeared more effective with the HV. Overall this study suggests that the HV may be a promising new technology. More work is needed to quantitatively assess its safety and efficacy.

  16. Rhetoric in visual arabic poetry: from the Mamluk period to the digital age

    Directory of Open Access Journals (Sweden)

    Eman Younis

    2015-07-01

    Full Text Available http://dx.doi.org/10.5007/1807-9288.2015v11n1p118 Rhetoric has been of great importance in philosophy, criticism and literature since Aristotle, through the Golden Age of Arabic studies and down to modern literary trends. Rhetoric is tightly bound with literary texts in all their manifestations and artistic, literary and analytic gradations. There are three aspects of rhetoric in every literary text of whatever type. One of these has to do with content, that is, with the author's ability to convince the receiver by alternately addressing his mind through logic and proofs and his heart by arousing in him feelings of desire and dread. This aspect of rhetoric is know in Arabic as ʿilm al-bayān (rhetoric in the strict sense. Another aspect concerns style, that is, a writer's ability to manipulate words and create novel linguistic modes through the use of metaphors, similes and other devices, which in Arabic is called ʿilm al-badīʿ ("the science of metaphors and good style". The third aspect concerns form, that is, the text's structure, its forms and icons. This is known as al-balāgha al-baṣriyya ("visual eloquence". Although there are various distinct types of balāgha ("eloquence, good style, rhetoric in the general sense", they all have one purpose, namely to affect the receiver in some way.

  17. Genome-scale modeling and transcriptome analysis of Leuconostoc mesenteroides unravel the redox governed metabolic states in obligate heterofermentative lactic acid bacteria.

    Science.gov (United States)

    Koduru, Lokanand; Kim, Yujin; Bang, Jeongsu; Lakshmanan, Meiyappan; Han, Nam Soo; Lee, Dong-Yup

    2017-11-16

    Obligate heterofermentative lactic acid bacteria (LAB) are well-known for their beneficial health effects in humans. To delineate the incompletely characterized metabolism that currently limits their exploitation, at systems-level, we developed a genome-scale metabolic model of the representative obligate heterofermenting LAB, Leuconostoc mesenteroides (iLME620). Constraint-based flux analysis was then used to simulate several qualitative and quantitative phenotypes of L. mesenteroides, thereby evaluating the model validity. With established predictive capabilities, we subsequently employed iLME620 to elucidate unique metabolic characteristics of L. mesenteroides, such as the limited ability to utilize amino acids as energy source, and to substantiate the role of malolactic fermentation (MLF) in the reduction of pH-homeostatic burden on F 0 F 1 -ATPase. We also reported new hypothesis on the MLF mechanism that could be explained via a substrate channelling-like phenomenon mainly influenced by intracellular redox state rather than the intermediary reactions. Model simulations further revealed possible proton-symporter dependent activity of the energy efficient glucose-phosphotransferase system in obligate heterofermentative LAB. Moreover, integrated transcriptomic analysis allowed us to hypothesize transcriptional regulatory bias affecting the intracellular redox state. The insights gained here about the low ATP-yielding metabolism of L. mesenteroides, dominantly controlled by the cellular redox state, could potentially aid strain design for probiotic and cell factory applications.

  18. Comparison of inverted flap and subretinal aspiration technique in full-thickness macular hole surgery: a randomized controlled study.

    Science.gov (United States)

    Iovino, Claudio; Caminiti, Giulia; Miccoli, Mario; Nasini, Francesco; Casini, Giamberto; Peiretti, Enrico

    2017-09-18

    To compare the inverted flap and the subretinal aspiration technique for full-thickness macular hole (FTMH) surgery. Forty consecutive eyes with a stage IV FTMH were randomly assigned into 2 treatment groups. After core vitrectomy and perimacular internal limiting membrane (ILM) peeling, in group A, the subretinal remnant macular fluid was aspirated with a 41-G cannula after the air-fluid exchange procedure, while in group B, the technique of an inverted ILM flap was completed. Differences in postoperative best-corrected visual acuity (BCVA) and occurrence of intraoperative or postoperative complications between the 2 groups were evaluated. All FTMHs were closed after the first surgery with no intraoperative or postoperative complications. In group A, 16 patients (80%) showed improvement of BCVA and 4 (20%) showed stabilization. In group B, 12 patients (60%) had improved BCVA, while 6 (30%) remained stable and 2 (10%) worsened. Postoperative BCVA for group A was significantly better than for group B (p = 0.022). The surgical techniques had similar rates of closure of FTMH, although BCVA outcomes were significantly better in the subretinal aspiration group.

  19. Chronic retinal effects by ultraviolet irradiation, with special reference to superoxide dismutases.

    Science.gov (United States)

    Oguni, M; Tamura, H; Kato, K; Setogawa, T

    1996-07-01

    Recently ultraviolet light (UV) reaching the Earth's surface has been gradually increasing in amounts by the destruction of the ozone layers. Large parts of UV are absorbed in the cornea and lens, and only a few amounts reached the retina; however, the effect on the retina is not fully elucidated. 38 rats were irradiated 0.5-5.0 J/cm2 UV from 6 to 50 times every 24 hours, and immunohistochemically and immunochemically for superoxide dismutases (SOD). Morphologically, the destruction of rod outer segments (ROS) and dissociation of cell membranes between the pigment epithelial cells (PE) were already observed by 6 times 0.5 J/cm2 UV irradiations. As the doses of UV increased, heterochromatins and lipid droplets increased in the PE. In normal retina, Cu/Zn SOD were mainly distributed from the inner limiting membrane (ILM) to the ganglion cell layer, and the PE; however, after 6 times 0.5 J/cm2 UV irradiations, the distribution became widened from inner to outer plexiform layer (OPL). At that time, the concentrations of Cu/Zn and Mn SOD increased in the retina. The present study reveals that the morphological damage caused by UV irradiation is observed in the ROS and PE, where no immunoreactivities could be detected to Cu/Zn and Mn SOD. However, morphological damage was not from the ILM to OPL, where the immunoreactivities to both Cu/Zn and Mn SOD were observed.

  20. BASİT EĞİLME ETKİSİNDEKİ BETONARME ELEMANLARIN MOMENT-EĞRİLİK VE TASARIM DEĞİŞKENLERİ ÜZERİNE ANALİTİK BİR İNCELEME

    Directory of Open Access Journals (Sweden)

    M. Yaşar KALTAKCI

    2001-01-01

    Full Text Available Bu çalışmada, basit eğilme etkisindeki betonarme elemanların tasarım değişkenlerinin analitik olarak incelenmesi amaçlanmış ve bu amaçla bir bilgisayar proğramı geliştirilmiştir. Eğilme tesiri altındaki betonarme elemanların dayanım ve davranışına beton basınç dayanımı, donatı çeliği çekme dayanımı, çekme, basınç ve sargı donatılarının miktarı ile donatıdaki pekleşme olayının etkisinin incelenmesi amaçlanmıştır. Bu amaçla geliştirilen bilgisayar programı, kabuk betonunun ezilmesini, donatıda pekleşmeyi, göbek betonu için sargı donatısı etkisini ve gerçekçi matematiksel malzeme modellerini göz önüne alabilen ve "katmanlı-modelleme" tekniğini kullanarak çözüm yapabilen FORTRAN dilinde bir programdır.

  1. AĞAÇ MALZEMEDE YANMAYI GECİKTİRİCİ VE SU İTİCİ KİMYASAL MADDELERİN EĞİLME DİRENCİNE ETKİLERİ

    Directory of Open Access Journals (Sweden)

    Hüseyin PEKER

    1999-01-01

    Full Text Available Bu çalışmada bor içerikli çeşitli kimyasal maddelerle emprenye edilmiş odunun statik eğilme direncinde meydana gelen değişimler incelenmiştir. Karşılaştırma için denemelerde polietilenglikol (PEG-400/P4, Amonyum sülfat (AS, Diamonyum fosfat (DAP ve organik çözücülü ticari bir emprenye maddesi olan Vacsol kullanılmıştır. Emprenye işlemlerinde tek işlemle bireysel kimyasal maddelerin kullanılması ve ikincil bir su itici madde (Water repellent = WR ile muamele edilerek hazırlanan deney planı uygulanmıştır. Deney sonuçlarına göre; asidik karakterdeki çözeltiler sarıçam eğilme direncinde azalmaya sebep olurken, kayında bazik çözeltiler daha olumlu sonuçlar vermiştir. Her iki türde de Polietilenglikol - 400 (P4 ve Borik asit + Borax (BA + BX sonrası uygulanan su itici madde uygulamalarında dikkate değer oranda direnç artışları sağlanamamıştır.

  2. Comparing the mode of action of intraocular lutein-based dyes with synthetic dyes.

    Science.gov (United States)

    Sousa-Martins, Diogo; Caseli, Luciano; Figueiredo, Mafalda C; Sa E Cunha, Claudia; Mota-Filipe, Helder; Souza-Lima, Acácio; Belfort, Rubens; Rodrigues, Eduardo; Maia, Mauricio

    2015-02-19

    To investigate and compare the mechanism by which lutein-based and synthetic intraocular dyes interact with their target membranes during ophthalmic surgeries. Surrogate membrane models were used in order to simulate the different intraocular membranes: internal limiting membrane (ILM), vitreous, anterior capsule (AC), and epiretinal membrane (ERM). Different lutein-based dyes, such as Phacodyne, Retidyne, Retidyne Plus, and Vitreodyne were tested, as well as Trypan Blue (TB), Indocyanine Green (ICG), Brilliant Blue (BB), and Triamcinolone Acetonide (TA). The interactions between the film components occurring at the air-water interface were investigated with surface pressure-area isotherms and polarization modulation infrared reflection-absorption spectroscopy (PM-IRRAS). With the exception of TA and ICG, none of the tested dyes revealed toxicity to the analyzed membranes. The interaction of TA with the vitreous model affected deeply the biointerface structure of the model. A significant condensation of the monolayer is noted when ICG contacted with ILM by the isotherms or even a solubilization of part of the monolayer toward the aqueous subphase. Retidyne Plus may provide the fluidization of the membrane, but maintains intact the structure of proteins present in the model. The present study demonstrates for the first time that lutein-based dyes interact through a physical mechanism of action with membrane models of structures present in human eye. On the other hand, the chemical interaction of synthetic dyes TA and ICG resulted in an alteration of the membrane models. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.

  3. Modeling two strains of disease via aggregate-level infectivity curves.

    Science.gov (United States)

    Romanescu, Razvan; Deardon, Rob

    2016-04-01

    Well formulated models of disease spread, and efficient methods to fit them to observed data, are powerful tools for aiding the surveillance and control of infectious diseases. Our project considers the problem of the simultaneous spread of two related strains of disease in a context where spatial location is the key driver of disease spread. We start our modeling work with the individual level models (ILMs) of disease transmission, and extend these models to accommodate the competing spread of the pathogens in a two-tier hierarchical population (whose levels we refer to as 'farm' and 'animal'). The postulated interference mechanism between the two strains is a period of cross-immunity following infection. We also present a framework for speeding up the computationally intensive process of fitting the ILM to data, typically done using Markov chain Monte Carlo (MCMC) in a Bayesian framework, by turning the inference into a two-stage process. First, we approximate the number of animals infected on a farm over time by infectivity curves. These curves are fit to data sampled from farms, using maximum likelihood estimation, then, conditional on the fitted curves, Bayesian MCMC inference proceeds for the remaining parameters. Finally, we use posterior predictive distributions of salient epidemic summary statistics, in order to assess the model fitted.

  4. Parameterizing Spatial Models of Infectious Disease Transmission that Incorporate Infection Time Uncertainty Using Sampling-Based Likelihood Approximations.

    Directory of Open Access Journals (Sweden)

    Rajat Malik

    Full Text Available A class of discrete-time models of infectious disease spread, referred to as individual-level models (ILMs, are typically fitted in a Bayesian Markov chain Monte Carlo (MCMC framework. These models quantify probabilistic outcomes regarding the risk of infection of susceptible individuals due to various susceptibility and transmissibility factors, including their spatial distance from infectious individuals. The infectious pressure from infected individuals exerted on susceptible individuals is intrinsic to these ILMs. Unfortunately, quantifying this infectious pressure for data sets containing many individuals can be computationally burdensome, leading to a time-consuming likelihood calculation and, thus, computationally prohibitive MCMC-based analysis. This problem worsens when using data augmentation to allow for uncertainty in infection times. In this paper, we develop sampling methods that can be used to calculate a fast, approximate likelihood when fitting such disease models. A simple random sampling approach is initially considered followed by various spatially-stratified schemes. We test and compare the performance of our methods with both simulated data and data from the 2001 foot-and-mouth disease (FMD epidemic in the U.K. Our results indicate that substantial computation savings can be obtained--albeit, of course, with some information loss--suggesting that such techniques may be of use in the analysis of very large epidemic data sets.

  5. Novel ionic liquid matrices for qualitative and quantitative detection of carbohydrates by matrix assisted laser desorption/ionization mass spectrometry.

    Science.gov (United States)

    Zhao, Xiaoyong; Shen, Shanshan; Wu, Datong; Cai, Pengfei; Pan, Yuanjiang

    2017-09-08

    Analysis of carbohydrates based on matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) is still challenging and researchers have been devoting themselves to efficient matrices discovery. In the present study, the design, synthesis, qualitative and quantitative performance of non-derivative ionic liquid matrices (ILMs) were reported. DHB/N-methylaniline (N-MA) and DHB/N-ethylaniline (N-EA), performing best for carbohydrate detection, have been screened out. The limit of detection for oligosaccharide provided by DHB/N-MA and DHB/N-EA were as low as 10 fmol. DHB/N-MA and DHB/N-EA showed significantly higher ion generation efficiency than DHB. The comparison of capacity to probe polysaccharide between these two ILMs and DHB also revealed their powerful potential. Their outstanding performance were probably due to lower proton affinities and stronger UV absorption at λ = 355 nm. What is more, taking DHB/N-MA as an example, quantitative analysis of fructo-oligosaccharide mixtures extracted and identified from rice noodles has been accomplished sensitively using an internal standard method. Overall, DHB/N-MA and DHB/N-EA exhibited excellent performance and might be significant sources as the carbohydrate matrices. Copyright © 2017 Elsevier B.V. All rights reserved.

  6. Rapid macular hole formation and closure in a vitrectomized eye following rhegmatogenous retinal detachment repair

    Directory of Open Access Journals (Sweden)

    Ratnesh Ranjan

    2018-01-01

    Full Text Available The development of a full-thickness macular hole (FTMH after pars plana vitrectomy (PPV for rhegmatogenous retinal detachment (RRD repair is a rare occurrence. We report the first case of rapid MH formation with internal limiting membrane (ILM-like hyper-reflective bridging membrane under silicone oil (SO meniscus, noted on the first postoperative day (POD postvitrectomy for RRD. A 57-year-old man presented with best-corrected visual acuity (BCVA of perception of light with immature cataract and total RRD in the left eye. He underwent cataract extraction with intraocular lens implantation with uneventful PPV, endolaser to primary break, and 360° periphery followed by injection of 1000 Cst SO. On the first POD, retina was attached in all quadrants with SO in situ. However, a dark red spot was noted at macula which was confirmed as FTMH with a bridging linear hyper-reflectivity under SO meniscus on optical coherence tomography (OCT. Repeat OCT, at 2 weeks and 3 months, revealed closed MH under the SO meniscus with BCVA improving to 6/60. This is the first reported case of very rapid FTMH formation with an ILM-like linear hyper-reflectivity following vitrectomy for RRD and highlights the possible contributory role of multiple nonconventional factors for rapid FTMH development and fibrinous membrane-assisted closure under SO tamponade.

  7. GPFS HPSS Integration: Implementation Experience

    Energy Technology Data Exchange (ETDEWEB)

    Hazen, Damian; Hick, Jason

    2008-08-12

    In 2005 NERSC and IBM Global Services Federal began work to develop an integrated HSM solution using the GPFS file system and the HPSS hierarchical storage system. It was foreseen that this solution would play a key role in data management at NERSC, and fill a market niche for IBM. As with many large and complex software projects, there were a number of unforeseen difficulties encountered during implementation. As the effort progressed, it became apparent that DMAPI alone could not be used to tie two distributed, high performance systems together without serious impact on performance. This document discusses the evolution of the development effort, from one which attempted to synchronize the GPFS and HPSS name spaces relying solely on GPFS?s implementation of the DMAPI specification, to one with a more traditional HSM functionality that had no synchronized namespace in HPSS, and finally to an effort, still underway, which will provide traditional HSM functionality, but requires features from the GPFS Information Lifecycle Management (ILM) to fully achieve this goal in a way which is scalable and meets the needs of sites with aggressive performance requirements. The last approach makes concessions to portability by using file system features such as ILM and snapshotting in order to achieve a scalable design.

  8. Phase Equilibria Modeling of Coesite Eclogite from the Sulu Belt, Eastern China

    Science.gov (United States)

    Xia, B.; Brown, M.; Wang, L.; Wang, S.; Piccoli, P. M.

    2016-12-01

    Modeling of phase equilibria and tectonic processes are essential components to understand controls on P-T paths of UHPM rocks. However, diffusion at higher temperatures (> 700 °C), and issues with determination of Fe3+ in minerals and estimating H2O contents limit our ability to determine prograde, peak P and retrograde P-T data. Also, the lack of an appropriate activity-composition model for melt in basic rocks has limited the application of phase equilibria modeling to understand partial melting associated with exhumation. Here we apply phase equilibria modeling to coesite eclogite from Yangkou to assess the influence of Fe3+ and fluid during metamorphism, monitor reactions and phase relations in eclogite during deep subduction and exhumation and investigate partial melting at HP conditions. The modeling used the THERMOCALC software and the new internally consistent thermodynamic dataset for basic rocks (http://www.metamorph.geo.uni-mainz.de/thermocalc/dataset6/index.html). Here we investigate bimineralic (gt+omp+coe/qz+ru/ilm), phengite-bearing (gt+omp+phen (2 samples, 5 vol%) +coe/qz+ru/ilm) and kyanite-bearing (gt+omp+phen+ky+coe/qz+ru/ilm) eclogites. Coesite in the matrix is the hallmark of the Yangkou eclogite. For each sample, we use an iterative process to estimate the H2O and O content in the bulk composition, and then calculate a P-T pseudosection. The results suggest that some prograde information (670-770 °C, > 3.0 GPa) is retained in large garnet cores in bimineralic and phengite-bearing eclogite. The peak P-T conditions are a challenge because in the field of gt+omp+coe/qz±phen+H2O at T > 750 °C and P > 3.5 GPa mode and compositional changes are small. However, isopleths of Si in phengite suggest that the peak P could have been > 5-6 GPa. Re-equilibration of garnet and omphacite compositions occurred during exhumation, yielding P-T conditions of 700-790 °C at 3.1-2.0 GPa. Amphibolite facies metamorphism occurred at 630-710 °C, 1.3-1.2 GPa. The

  9. Vitrectomy and internal limiting membrane peeling for macular folds secondary to hypotony in myopes

    Directory of Open Access Journals (Sweden)

    Nadal J

    2015-05-01

    Full Text Available Jeroni Nadal,1–3 Elisa Carreras,2,3 Maria Isabel Canut,1–3 Rafael I Barraquer1–3 1Centro de Oftalmologia Barraquer, 2Universitat Autònoma de Barcelona, 3Instituto Barraquer, Barcelona, Spain Background: Hypotony maculopathy (HM changes may persist, and visual acuity remains poor, despite normalization of intraocular pressure (IOP. The aim of this study was to evaluate the visual and anatomical results of pars plana vitrectomy (PPV, internal limiting membrane (ILM peeling, and 20% SF6 gas tamponade in five myopic patients with HM.Methods: This retrospective interventional study was conducted at the Barraquer Center of Ophthalmology, a tertiary care center in Barcelona, Spain, and included five eyes from five consecutive patients (aged 55.4±13.1 years with HM caused by different conditions. All the patients were treated with 23-gauge PPV, ILM peeling, and 20% SF6 gas tamponade. Preoperative and postoperative evaluation was performed using anterior and posterior biomicroscopy and best corrected visual acuity (BCVA by logMAR charts.Results: Before surgery, median spherical equivalent was -13.1 (range -7, -19 diopters of myopia. Preoperatively, four cases presented IOP <6.5 mmHg for 3 (range 2–8 weeks. In three of these four cases, IOP >6.5 mmHg was achieved over 16 (range 16–28 weeks, without resolution of HM; increased IOP was not achieved in the remaining case treated 2 weeks after diagnosis of HM. One case presented IOP >6.5 mmHg with HM for 28 weeks before surgery. Preoperative BCVA was 0.7 (range 0.26–2.3 logMAR, and 0.6 (range 0.3–0.7 logMAR and 0.5 (range 0.2–1 logMAR, respectively, at 4 and 12 months after surgery. There was no statistically significant difference between preoperative and postoperative BCVA. Hyperpigmentation lines in the macular area were observed in three cases with hypotony. These lines progressed after surgery despite resolution of the retinal folds in the three cases, and BCVA decreased in parallel

  10. Petrology of the zoned calcalkaline magma chamber of Mount Mazama, Crater Lake, Oregon

    Science.gov (United States)

    Druitt, T.H.; Bacon, C.R.

    1989-01-01

    Evolution of the magma chamber at Mount Mazama involved repeated recharge by two types of andesite (high-Sr and low-Sr), crystal fractionation, crystal accumulation, assimilation, and magma mixing (Bacon and Druitt 1988). This paper addresses the modal compositions, textures, mineral chemistry and magmatic temperatures of (i) products of the 6845??50 BP climactic eruption, (ii) blocks of partially fused granitoid wallrock found in the ejecta, and (iii) preclimactic rhyodacitic lavas leaked from the chamber in late Pleistocene and early Holocene time. Immediately prior to the climactic eruption the chamber contained ??? 40 km3 of rhyodacite (10 vol% plag + opx + aug + hb + mt + ilm, ???880?? C) overlying high-Sr andesite and cumulus-crystal mush (28-51 vol% plag + hb ?? opx ?? aug + mt ?? ilm, 880?? to ???950?? C), which in turn overlay low-Sr crystal mush (50-66 vol% plag + opx + aug ?? hb ?? ol + mt + ilm, 890?? to ???950??? C). Despite the well known compositional gap in the ejecta, no thermal discontinuity existed in the chamber. Pre-eruptive water contents of pore liquids in most high-Sr and low-Sr mushes were 4-6 wt%, but on average the high-Sr mushes were slightly richer in water. Although parental magmas of the crystal mushes were andesitic, xenocrysts of bytownite and Ni-rich magnesian olivine in some scoriae record the one-time injection of basalt into the chamber. Textures in ol-bearing scoriae preserve evidence for the reactions ol + liq = opx and ol + aug + liq(+ plag?) = hb, which occurred in andesitic liquids at Mount Mazama. Strontium abundances in plagioclase phenocrysts constrain the petrogenesis of preclimactic and climactic rhyodacites. Phenocryst cores derived from high-Sr and low-Sr magmas have different Sr contents which can be resolved by microprobe. Partition coefficients for plagioclase in andesitic to rhyolitic glasses range from 2 to 7, and increase as glass %SiO2 increases. Evolved Pleistocene rhyodacites (???30-25,000 BP) and

  11. Optimal management of idiopathic macular holes

    Directory of Open Access Journals (Sweden)

    Madi HA

    2016-01-01

    Full Text Available Haifa A Madi,1,* Ibrahim Masri,1,* David H Steel1,2 1Sunderland Eye Infirmary, Sunderland, 2Institute of Genetic Medicine, Newcastle University, International Centre for Life, Newcastle, UK *These authors contributed equally to this work Abstract: This review evaluates the current surgical options for the management of idiopathic macular holes (IMHs, including vitrectomy, ocriplasmin (OCP, and expansile gas use, and discusses key background information to inform the choice of treatment. An evidence-based approach to selecting the best treatment option for the individual patient based on IMH characteristics and patient-specific factors is suggested. For holes without vitreomacular attachment (VMA, vitrectomy is the only option with three key surgical variables: whether to peel the inner limiting membrane (ILM, the type of tamponade agent to be used, and the requirement for postoperative face-down posturing. There is a general consensus that ILM peeling improves primary anatomical hole closure rate; however, in small holes (<250 µm, it is uncertain whether peeling is always required. It has been increasingly recognized that long-acting gas and face-down positioning are not always necessary in patients with small- and medium-sized holes, but large (>400 µm and chronic holes (>1-year history are usually treated with long-acting gas and posturing. Several studies on posturing and gas choice were carried out in combination with ILM peeling, which may also influence the gas and posturing requirement. Combined phacovitrectomy appears to offer more rapid visual recovery without affecting the long-term outcomes of vitrectomy for IMH. OCP is licensed for use in patients with small- or medium-sized holes and VMA. A greater success rate in using OCP has been reported in smaller holes, but further predictive factors for its success are needed to refine its use. It is important to counsel patients realistically regarding the rates of success with

  12. Luuleaasta 1994 : parlamendi koosseis on selgunud / Barbi Pilvre

    Index Scriptorium Estoniae

    Pilvre, Barbi, 1963-

    1995-01-01

    Rannit, Aleksis. Nii näen sind ikka; Kangur, Kalju. Sõna sees olek; Traat, Mats. Koidu kätes; Rimmel, Rudolf. Setu netu; Suislepp, Harald. Köögertali kojutulek; Piir, Enno. Sunnitöölise Mekka; Üllaste, Leenart. Lind tormis; Hirv, Indrek. Taskuraamat (taskutähekerjus); Mirtem, Valev [Luhaäär, Ingvar]. Maithunad Eestis; Mirtem, Valev [Luhaäär, Ingvar]. Armuühtepühad; Mirtem, Valev [Luhaäär, Ingvar]. Tulevaas; Kurvits, Lembit. Matle laul; Lillemets, Enn. Olemise valge koer ehk Ingli kolju; Jessod, Mats [Jakobson, Mati]. Jah, luuletused; Jessod, Mats [Jakobson, Mati]. Ohjad Oti mäel; Jessod, Mats [Jakobson, Mati]. Poeetilisi prohmakaid; Ivar, Ivo. Riimiskid; Kilokalor, Kalle. Öösel näeb halvemini kui päeval; Trubetsky, Tõnu. Anarhia; Laanvee, Ervin. Jaa. Mina olen; Kuningas, Marko J. ...jääb USK, LOOTUS, ARMASTUS; Ruben, Arne. Ajakirjanik; Ollinovski, Jim [Ollino, Ott]. Luuletused; Toomik, Tõnu. 27 luuletust; Tosin, Ants. Õnnetähestik; Krüger, Urmas. Ka nii võib...; Kärner, Siim. Usseaid; Sikk, Heino. Võrokõstõlõ: poeem; Kollin, Viktor. Kodutunne; Alo, Ülo [Võsar, Ülo Alo]. Ööbikuvalgus; Sepp, Vello. Vigased pärlid; Palo, Wilhelm. Tuule-luuled; Soomets, Triin. Randmes unejanu; Soomets, Triin. Janu masinas; Ränik, Valeria. Ajast väljas; Kivi, Aita. Kalender-päevik Aita Kivi luuletustega; Maagemust, Maarika. Kaaludes kaldaid; Hiiussaar, Ann. Valgete uste taga; Kolkkanen, Imbi. Mina ja maailm; Mets, Neeme. Kesalill; Kolesnitshenko, Kaidi-Ly. Kaks silma; Kahro, Anne. Nälkjast!; Kabe, Aino. Tuulema mõtteriim. Raatma, Salme. Laululatern; Osila, Virve. Lootuse luiged; Isak, Asta. Valguse ja varjude vahel; Õunapuu, Meeli. Mööda teid ja radu

  13. Aedemon

    OpenAIRE

    Gascou, J.

    2013-01-01

    Affranchi de Juba II, ou, plus probablement, de Ptolémée, le dernier roi de Maurétanie. Comme ces deux princes étaient des citoyens romains et portaient tous deux le nom de C. Iulius, le nom complet d’Aedemon était certainement C. Iulius Aedemon : on a peut-être une trace de cette dénomination dans l’inscription I.L.M 116 = Inscriptions antiques du Maroc, 2, 448, où, au-dessus du d d’Aedemonem, L. Chatelain note : « deux petites lettres ou signes, i u ou l u, comme si le lapicide avait pensé ...

  14. Mistisisme dalam Perspektif Filsafat Analitik: Antara Wittgenstein dan Mehdi Ha'iri Yazdi

    Directory of Open Access Journals (Sweden)

    M. Hidayatullah S.

    2007-12-01

    Full Text Available Language is a principal instrument for philosopher and as a medium for analysis and reflection. Wittgenstein said, that the order analytical philosophy is to clean away the epistemology from the "good" terms but unclear in it interpretation. Every thing that can be thinks must be able spoken. The limits of my language mean the limits of my world. From this perspective mysticism and mystics experience is nin-sense, because nothing factual reference. From this case, the goal of this study is to find out the epistemology in mysticism and mystic experience. In the study we include the knowledge by presence (ilm al-hudhuri Ha 'iri as an approach. Ha 'iri said that there is a other knowledge which that can be explanations in limits of language and picture theory. This is knowledge by peresence, which by Wittgenstein aware as some thing which having difference language games from knowledge by correspondece.

  15. KAYIN, KAVAK VE HUŞ SOYMA KAPLAMALARINDAN FARKLI KOMBİNASYONLARDA ATIK NAYLON İLE ÜRETİLEN KONTRPLAKLARIN BAZI TEKNOLOJİK ÖZELLİKLERİ

    OpenAIRE

    DEMİR, Aydın; ÖZTÜRK, Hasan; ÇOLAK, Semra

    2017-01-01

    Bu çalışmada, kontrplaksektöründe kullanılan formaldehit esaslı reçineler yerine bağlayıcı olarak atıknaylonların (polietilen) kullanılmasıyla kayın (Fagus Orientalis Lipsky), kavak (Populus deltoides)  ve huş (Betula pendula)  soyma kaplamalarının kombinasyonlarındanüretilmiş levhaların bazı teknolojik özelliklerinin araştırılması amaçlanmış veüretilmiş levha kombinasyonları için optimum naylon miktarları belirlenmeyeçalışılmıştır. Bu amaçla, üç farklı naylon miktarı seçilm...

  16. [Pathology of the vitreomacular interface].

    Science.gov (United States)

    Pop, Monica; Gheorghe, Alina

    2014-01-01

    Vitreous role in the pathophysiology of retinal diseases has increased importantly over the recent years. This was possible using Optical Coherence Tomography which reviewed the way the vitreoretinal interface should be looked at and defined and classified new pathologies such as Vitreoretinal Traction Syndrome. Vitreous is not an empty space but an important anatomical structure with role in ocular physiology. With age biochemical changes occur so that vitreous starts to liquefy. Once the vitreous is liquefied (sinchisis) it collapses and passes in the retrohialoid space (sineresis). In complete PVD besides sinchisis there is a weakness of the adherence between the posterior cortex and ILM with total detachment of posterior cortex. Abnormal adhesions are associated with incomplete PVD. The definition and understanting of vitreoretinal pathology is an active and continuous process, PVD being the trigger of a lot of retinal pathologies: epiretinal membrane, macular hole, tractional macular oedema, VMTS, myopic traction maculopathy, exacerbations of exudative ARMD.

  17. Understanding cellulose dissolution: energetics of interactions of ionic liquids and cellobiose revealed by solution microcalorimetry.

    Science.gov (United States)

    de Oliveira, Heitor Fernando Nunes; Rinaldi, Roberto

    2015-05-11

    In this report, the interactions between fifteen selected ionic liquids (ILs) and cellobiose (CB) are examined by high-precision solution microcalorimetry. The heat of mixing (Δmix H) of CB and ILs, or CB and IL/molecular solvent (MS) solutions, provides the first ever-published measure of the affinity of CB with ILs. Most importantly, we found that there is a very good correlation between the nature of the results found for Δmix H(CB) and the solubility behavior of cellulose. This correlation suggests that Δmix H(CB) offers a good estimate of the enthalpy of dissolution of cellulose even in solvents in which cellulose is insoluble. Therefore, the current findings open up new horizons for unravelling the intricacies of the thermodynamic factors accounting for the spontaneity of cellulose dissolution in ILs or IL/MS solutions. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Greco Laser-matter interaction

    International Nuclear Information System (INIS)

    1986-01-01

    Research program in 1985 at GRECO ILM (Group of Coordinated Research: Interaction Laser Matter) continued with its principal direction in fundamental physics of laser inertial confinement; also researches on X-ray lasers hare been undergone and new high power laser application fields with particle acceleration, material processing and X-ray sources. A six beam laser was operated. Wavelength effects were studied. Atomic physics was deeply stressed as dense medium diagnostics from multicharged ions. Research development in ultra-dense medium was also important X-ray laser research gave outstanding results. New research fields were developed this year: laser acceleration of particles by wave beating or Raman instability; dense laser produced plasma use as X-ray source; material processing by laser shocks [fr

  19. ISLAMIC SCIENCE, NATURE AND HUMAN BEINGS: A DISCUSSION ON ZIAUDDIN SARDAR'S THOUGHTS

    Directory of Open Access Journals (Sweden)

    Masthuriyah Sa’dan

    2015-12-01

    Pada era sekarang ini perkembangan sains telah mengalami kemajuan yang sangat pesat. Namun kemajuan sains hanya mengambil keuntungan sebesar-besarnya, tanpa memikirkan dampak dari perkembangan sains itu sendiri. Sains telah memarginalkan sisi metafisika dan teologi sehingga sains Barat me­nimbul­kan sifat materialistis bagi manusia, kerusakan ekologi, dan ketidak­harmonisan antara alam dan manusia. Tulisan ini mengkaji pemikiran Ziauddin Sardar tentang sains Islam dengan pendekatan analisis deskriptif. Dalam pandangan Sardar, masyarakat Muslim tidak harus mengekor sains Barat, akan tetapi masyarakat Muslim bisa memiliki sains sebagai karakteristik sains yang bercorak dan bernilai Islam yakni sains Islam. Adapun karaketeristik sains Islam tidak lepas dari sepuluh parameter yang meliputi tawḥīd, khilāfah, ’ibādah, ’ilm, ḥalāl, ḥarām, ’adl, ẓulm, istiṣlāḥ dan diyā’.

  20. [Traumatic macular hole with central retinal detachment and choroidal rupture with ora serrata dialysis].

    Science.gov (United States)

    Fiorentzis, M; Seitz, B; Viestenz, A

    2015-08-01

    Closed ocular trauma is associated with various retinal complications, such as Berlin's edema, peripheral retinal tears, retinal hemorrhage, choroidal rupture, subretinal bleeding and macular holes. Traumatic macular holes (TMH) are rare and surgical intervention is controversial due to possible spontaneous closure. The positive development in the patient described here indicates that a pars plana vitrectomy with drainage of subretinal hemorrage combined with peeling of the internal limiting membrane (ILM) for a penetrating traumatic macular hole with choroidal rupture can lead to the restoration of visual acuity. The anti-vascular endothelial growth factor (VEGF) therapy (under silicone oil with avastin 0.02 ml) can successfully lead to limitation of posttraumatic choroidal neovascularization (CNV). Patients with ocular contusion require extensive long-term ophthalmological follow-up. Furthermore, prevention, education and information is essential to prevent serious injuries.

  1. 戦略的人的資源管理とキャリア形成・人材育成に関する研究

    OpenAIRE

    佐藤, 厚

    2013-01-01

    研究成果の概要(和文):人的資源管理とキャリア形成・人材育成との関連について考察するために、事例調査を試みた結果、 (a) 内部労働市場的対応と (b) 職業別労働市場(もしくは外部労働市場)的対応の二つのパタンが見出された。ここから、後者 (b) の性格の強い中小企業の場合、仕事能力を明確化し、技能形成のための環境整備をはかることが重要であり、加えて社会的に職業能力を評価し、能力形成をはかるためのしくみの整備が必要となる、という政策的含意を得た。研究成果の概要(英文):According to case study on human resource management, career formation, and human resource development, two type of firms were found out. That is (a) Internal Labor Market (ILM) typed firm, and (b) Occupational Labor Market(OLM) typed firm. Compare with ILM t...

  2. Intrusive and Non-Intrusive Load Monitoring (A Survey

    Directory of Open Access Journals (Sweden)

    Marco Danilo Burbano Acuña

    2015-05-01

    Full Text Available There is not discussion about the need of energyconservation, it is well known that energy resources are limitedmoreover the global energy demands will double by the end of2030, which certainly will bring implications on theenvironment and hence to all of us.Non-Intrusive load monitoring (NILM is the process ofrecognize electrical devices and its energy consumption basedon whole home electric signals, where this aggregated load datais acquired from a single point of measurement outside thehousehold. The aim of this approach is to get optimal energyconsumption and avoid energy wastage. Intrusive loadmonitoring (ILM is the process of identify and locate singledevices through the use of sensing systems to support control,monitor and intervention of such devices. The aim of thisapproach is to offer a base for the development of importantapplications for remote and automatic intervention of energyconsumption inside buildings and homes as well. For generalpurposes this paper states a general framework of NILM andILM approaches.Appliance discerns can be tackled using approaches fromdata mining and machine learning, finding out the techniquesthat fit the best this requirements, is a key factor for achievingfeasible and suitable appliance load monitoring solutions. Thispaper presents common and interesting methods used.Privacy concerns have been one of the bigger obstacles forimplementing a widespread adoption of these solutions; despitethis fact, developed countries like those inside the EU and theUK have established a deadline for the implementation ofsmart meters in the whole country, whereas USA governmentstill struggles with the acceptance of this solution by itscitizens.The implementation of security over these approachesalong with fine-grained energy monitoring would lead to abetter public agreement of these solutions and hence a fasteradoption of such approaches. This paper reveals a lack ofsecurity over these approaches with a real scenario.

  3. Independent assessment of matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) sample preparation quality: Effect of sample preparation on MALDI-MS of synthetic polymers.

    Science.gov (United States)

    Kooijman, Pieter C; Kok, Sander; Honing, Maarten

    2017-02-28

    Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) provides detailed and in-depth information about the molecular characteristics of synthetic polymers. To obtain the most accurate results the sample preparation parameters should be chosen to suit the sample and the aim of the experiment. Because the underlying principles of MALDI are still not fully known, a priori determination of optimal sample preparation protocols is often not possible. Employing an automated sample preparation quality assessment method recently presented by us we quantified the sample preparation quality obtained using various sample preparation protocols. Six conventional matrices with and without added potassium as a cationization agent and six ionic liquid matrices (ILMs) were assessed using poly(ethylene glycol) (PEG), polytetrahydrofuran (PTHF) and poly(methyl methacrylate) (PMMA) as samples. All sample preparation protocols were scored and ranked based on predefined quality parameters and spot-to-spot repeatability. Clearly distinctive preferences were observed in matrix identity and cationization agent for PEG, PTHF and PMMA, as the addition of an excess of potassium cationization agent results in an increased score for PMMA and a contrasting matrix-dependent effect for PTHF and PEG. The addition of excess cationization agent to sample mixtures dissipates any overrepresentation of high molecular weight polymer species. Our results show reduced ionization efficiency and similar sample deposit homogeneity for all tested ILMs, compared with well-performing conventional MALDI matrices. The results published here represent a start in the unsupervised quantification of sample preparation quality for MALDI samples. This method can select the best sample preparation parameters for any synthetic polymer sample and the results can be used to formulate hypotheses on MALDI principles. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  4. Evaluation of Ganglion Cell-Inner Plexiform Layer Thickness after Vitreoretinal Surgery with Internal Limiting Membrane Peeling in Cases with Idiopathic Macular Hole

    Directory of Open Access Journals (Sweden)

    Sibel Demirel

    2017-06-01

    Full Text Available Objectives: To evaluate macular retinal ganglion cell-inner plexiform layer (GCIPL thickness after vitrectomy with internal limiting membrane (ILM peeling for idiopathic macular holes using spectral domain optical coherence tomography (SD-OCT. Materials and Methods: Eighteen eyes of 18 patients with unilateral idiopathic macular hole who underwent vitrectomy with ILM peeling were retrospectively analyzed. Healthy fellow eyes of the patients and 18 eyes of 18 age-matched healthy individuals constituted the control group. The patients were evaluated at 1 day, 1 week, 1 month, and 3 months after surgery. The best corrected visual acuity (BCVA measurements, biomicroscopic examination findings and SD-OCT measurements were recorded. Ganglion cell-inner plexiform layer thickness was evaluated with ganglion cell analysis software of Cirrus HD-OCT before surgery and at 1 month and 3 months after surgery and compared with control groups. Presence of dissociated optic nerve fiber layer (DONFL was evaluated with C-scan mode. Results: Of the 18 patients, 9 were male and 9 were female with a mean age of 65.6±5.6 (55-77 years. Preoperative BCVA was 0.75±0.19 logMAR, while it was 0.44±0.17 logMAR and 0.36±0.15 logMAR at postoperative 1 and 3 months, respectively (p0.05. Conclusion: Internal limiting membrane peeling during macular hole surgery may cause functional and /or structural changes that may be associated with visual acuity. Significant GCIPL thinning and DONLF appearance may occur postoperatively.

  5. An international labour migration to developing countries in Asia: a case study of Korea.

    Science.gov (United States)

    Kim, J K

    1996-12-01

    This study is based on a random sample of 431 temporary migrant workers from developing countries in Korea. Interviews were conducted from mid-October 1995 to mid-March 1996 with 105 Pakistanis, 77 Filipinos, 71 Sri Lankans, 67 Bangladeshi, 40 Indonesians, 26 individuals from Myanmar, 22 Chinese, 16 Nepalese, 2 Iranians, 2 Kazakstanians, 1 Malaysian, 1 Vietnamese, and 1 Ghanaian. Migration follows legal and illegal patterns. Legal trainee migrants leave before their contract time due to low pay, inadequate living conditions, forced overtime work, and lack of freedom. Trainees tend to be ethnic Koreans born in China and Chinese nationals. The number of illegal migrants is increasing. Foreign workers gain entry illegally through smuggling networks and legally through industrial work or tourist visas. Sample data reveal that the average age ranged from 26 to 32 years. Almost 70% were unmarried, and most were males. Filipinos tended to be older and show gender and marital balance. Age, marital status, religion, and education varied widely by ethnic group. Indonesians and Sri Lankans had lower household income than Pakistanis and Filipinos. Pakistanis tended to come from larger families. Total travel costs ranged from $3000 to $5000. Korea is one of four rapidly developing countries that shifted from being a major exporter of labor to a major importer of workers. Shortages of workers accompanied the shift. This case study illustrates that the traditional structural paradigm does not explain some unique features of international labor migration (ILM) in Asia, including the encouragement of illegal migration. The clandestine networks are different from those in developed countries. State policies mediate the flow of ILM.

  6. Contesting a National Cinema in Becoming: The Cinemalaya Philippine Independent Film Festival (2005-2014

    Directory of Open Access Journals (Sweden)

    Emerald O. Flaviano

    2017-12-01

    Full Text Available Since its birth in 2005, the Cinemalaya Philippine Independent Film Festival has proven itself a major force in the Philippine f ilm industry. Established with the twin goals of “[encouraging] the creation of new cinematic works by Filipino filmmakers—works that boldly articulate and freely interpret the Filipino experience with fresh insight and artistic integrity” and “[invigorating] Philippine filmmaking by developing a new breed of Filipino filmmakers,” Cinemalaya has been instrumental in the recent rise of what Tiongson (“The Rise of the Philippine New Wave Indie Film” has called the “New Wave Indie” films. This recent wave of independent cinema, in turn, is taken to be the next significant moment in the history of Philippine national cinema. By considering the film festival—a spatiotemporally demarcated event and a unique discoursegenerating institution—as point of entry, this article discusses the contested process of constructing a coherent narrative of becoming of a national cinema. This process is found, more than ever, to surface resistance to any singular notion of “national cinema,” not least because of the inescapably transnational nature of all film production and consumption. It is within this context that any discussion about “saving” a Philippine national cinema is framed, particularly as to how international recognition has legitimized local independent cinema and influenced local spectatorship practices. Cinemalaya has helped revive a failing industry by giving shape to a new film movement, essentially def ined by contestation, as the f ilm festival’s experience in moderating the controversies it has found itself embroiled in has proven. More than anything, these contestations have brought to the fore previously unchallenged assumptions about what cinema a national public deserves to see.

  7. Seamless user experiences in a brand new library

    KAUST Repository

    Vijayakumar, J.K.

    2012-10-30

    In order to provide seamless user experiences, the brand new libraries are far better positioned. They do not have to manage much in print, at least for the journal section, but huge electronic collection accessible via Internet. They do not worry about migrating to new systems or technology; they just start with whatever the latest available in the market, whether it is new generation ILMS, discovery tools, content management systems, mobile technologies, cloud computing etc. Patrons\\' expectations for seamless experience are met - regardless of their location, device and service they opted for. The story of the two and half years old, Saudi Arabia\\'s brand new King Abdullah University of Science and Technology\\'s Library is not different. Huge amount of electronic resources also provide ever increasing challenges to the new generation libraries in collecting, organizing and delivering the right information, to the right person at the right time. Implementation of a good ILMS supported with better electronic resource management features will help in setting the house right. Well-designed user interfaces, supported with the web scale discovery tools will help the users to have a better search experience. Availability of library collection through the campus mobile applications, latest proxy technologies for out-campus access and integrating the resources to the campus e-learning platform are the main features of the library’s seamless experiences. Libguide platform is used for the first time in Saudi Arabia, to create online research guides by subject librarians. An institutional repository, based on D-Space platform is about to release. Ninety percent of our collection is online; they are purchased, organized and accessed online, like any other brand new academic research libraries. Analysis of usage statistics of different resources show that they are highly used and usage is increased over two years, as the technology improved and implemented.

  8. Optical Coherence Tomography Angiography Findings in Stargardt Disease.

    Directory of Open Access Journals (Sweden)

    Rodolfo Mastropasqua

    Full Text Available to assess vessel density of superficial capillary plexus (SCP, deep capillary plexus (DCP and choriocapillaris (CC in advanced Stargardt disease (STGD using optical coherence tomography angiography (OCTA and correlate these findings with macular function using pattern electroretinogram (PERG and multifocal electroretinogram (mfERG.Twelve patients (24 eyes with advanced STGD underwent vessel densities and macular thickness measurements using OCTA. A control group of 24 healthy controls (24 eyes was chosen for comparison. In the STGD group correlation between vessel density and macular thickness and between macular function and morphologic parameters were evaluated.Whole parafoveal vessel density (VD of SCP was significantly lower in STGD group compared to the control group (p<0.05. Foveal VD and whole parafoveal VD of the DCP were significantly lower in STGD group compared to the controls (p<0.05. CC was significantly decreased in STGD compared to controls (p<0.05. Foveal macular thickness (MT, full parafoveal MT, and inner limiting membrane (ILM-inner plexiform layer (IPL parafoveal MT thickness were decreased in STGD eyes compared to controls (p<0.001. PERG and mfERG were both significantly reduced in STGD compared to controls (p<0.001. A direct correlation was found between full parafoveal MT and vessel density in the STGD group.Patients with advanced STGD showed a reduction of SCP, DCP and CC compared to healthy eyes related to a reduction of total and ILM-IPL macular thickness. These results suggest that both retinal capillaris plexuses and choriocapillaris reduction occur in STDG along with inner and outer retinal thinning.

  9. Hyalocytes in idiopathic epiretinal membranes: a correlative light and electron microscopic study.

    Science.gov (United States)

    Schumann, Ricarda G; Gandorfer, Arnd; Ziada, Jean; Scheler, Renate; Schaumberger, Markus M; Wolf, Armin; Kampik, Anselm; Haritoglou, Christos

    2014-12-01

    To describe characteristics of epiretinal cells at the vitreoretinal interface by correlative light and electron microscopy (CLEM). Epiretinal membrane (ERM) specimens and internal limiting membrane (ILM) specimens were harvested by sequential peeling during vitrectomy from 27 eyes with idiopathic epiretinal gliosis, and processed for CLEM. Intraoperatively, the presence of posterior vitreous detachment (PVD) was documented. We used anti-vimentin, anti-α-smooth muscle actin (α-SMA), and anti-CD45 as primary antibodies. A fluorescein-tagged immunonanogold cluster was used as secondary antibody and visualized under the fluorescence and transmission electron microscope. We demonstrated CD45-positive cells specifically labelled at their plasma membranes with ultrastructural features known for hyalocytes, such as oval nucleus with marginal chromatin, vacuoles, dense granules, and thin cytoplasmic protrusions. CD45-positive cells were mostly located on a thick layer of native vitreous collagen. They were covered by newly formed collagen strands with multilayered proliferation of myofibroblasts. We also demonstrated immunoreactivity for vimentin and alpha-SMA. Cell fragments with positive labelling for α-SMA and vimentin were not only found on the vitreal side of the ILM, but also on the retinal side. By CLEM, the majority of CD45-positive cells in epiretinal cell proliferation were characterized as hyalocytes. In the context of anomalous PVD and vitreoschisis, ultrastructural features and topographic localization of hyalocytes suggest that these cells play a significant role in ERM formation. CLEM enables a more accurate characterization of epiretinal cell proliferation, and therefore, contributes to a better understanding of the pathogenesis of diseases at the vitreoretinal interface.

  10. Tenomodulin Inhibits Retinal Neovascularization in a Mouse Model of Oxygen-Induced Retinopathy

    Directory of Open Access Journals (Sweden)

    Tatsuhiko Sato

    2012-11-01

    Full Text Available We aimed to determine the anti-angiogenic effect of tenomodulin (TeM on retinal neovascularization in an oxygen-induced retinopathy (OIR mouse model. OIR was induced in C57BL/6 mice by exposing seven-day-old mice to 75% oxygen for five days followed by room air for five days. Control mice were exposed to room air from birth until postnatal day 17. Mice received intravitreal injections of 1 μg of TeM in one eye and PBS in the contralateral eye at P7 before being exposed to 75% oxygen. Eyes were collected at postnatal day 17. Retinal blood vessel patterns were visualized by fluorescein angiography. We quantified the number of neovascular nuclei that were present beyond the inner limiting membrane (ILM using histological methods with a masked approach. Furthermore, double immunohistochemical staining of TeM was performed on retinas to identify nuclei protruding into the vitreous cavity. Western blot was used to detect exogenous TeM protein. The central nonperfusion area (NPA, mm2 of TeM-injected eyes was significantly different from that of OIR and PBS-injected eyes, and the number of nuclei in new blood vessels breaking through the ILM in each retinal cross-section significantly differed from that of OIR eyes and PBS-injected control eyes. Cellular nuclei of new blood vessels protruding into the vitreous cavity were also observed in TeM-injected retinas by immunohistochemistry. Western blotting revealed a 16-kDa immunoreactive protein, indicating incorporation of an exogenous TeM fragment into the retina. Our data shows that TeM can effectively inhibit pathological angiogenesis in mouse eyes; indicating its potential role in prevention and treatment of ocular neovascularization.

  11. S-35: Aynı Yaş Kategorisinde Farklı Başarı Seviyesindeki Erkek Futbolcuların Lig Performanslarının Karşılaştırılması

    Directory of Open Access Journals (Sweden)

    Raziye Dut

    2017-03-01

    Full Text Available GİRİŞ: Futbola erken yaşta başlamak, yeteneğin ortaya çıkarılması ve doğru geliştirilmesi zor ve uzun bir süreçtir. Bu süreçte hem yetenekli hem de iyi yönlendirilmiş olan futbolcular milli takım kamplarına davet edilmekte ve milli futbolcu olmanın ilk adımlarını da atmış olmaktadır.AMAÇ: U-14 yaş kategorisinde milli takım seçilme kampına davet edilmiş erkek futbolcuların diğer ülke genelinde akademi liglerinde futbol oynayan aynı kronolojik yaştaki davet edilmeyen akranlarından lig performans farklılıklarını göstermektir.GEREÇ-YÖNTEM: 2016-2017 sezonunda akademi liglerinde futbol oynayan U-14 2050 erkek futbolcudan milli takıma seçilme kampına davet edilen 213 futbolcunun ligin ilk yarı döneminde davet edilmeyen akranlarından futbola spesifik lig performans farklarını inceledik. Veriler n ve % veya ortanca ve Inter Quartile Rate (IQR olarak özetlendi. Gruplar arası farklılıkların saptanmasında Mann-Whitney U testi kullanıldı.. P<0,05 istatistiksel anlamlı kabul edildi.BULGULAR: Yaş çeyrekleri sırasıyla 122 (%57,3, 49 (523, 30 (%14,1 ve 12(%5,6 idi. 2016-2017 sezonunda şubat ayına kadar oynadıkları maç sayıları 12 (IQR: 5-12, dakika 681 (245-1183,2, sarı kart sayısı 0 (0-1, gol sayıları 0 (0-2 olduğu görüldü. Milli takıma seçilme kampına davet edilen futbolcuların edilmeyenlere göre daha fazla maç ve oyun dakikası oynadığı (p<0,001, daha fazla gol attığı (p<0,001 ve daha az sarı kart aldığı (p<0,001 saptandı. Lig maçlarında milli takıma seçilme kampına davet edilen futbolcuların 5 kişiden biri 1 gol atarken davet edilmeyenlerden 10 kişiden biri 1 gol attığı, davet edilenlerin oynadıkları maçlarda 2,77 maçta bir gol atılırken, davet edilmeyenlerin oynadıkları her 8,78 maçtan birinde bir gol atıldığı görüldü. Kampa davet edilmeyen sporcular oynadıkları her 581,28 dakikada bir gol atılırken, davet edilenlerde 218

  12. LA PSICOLOGIA PARAGUAYA REPRESENTADA EN LA PSICOLOGIA DE JAMES O. WHITTAKER Y SANDRA J. WHITTAKER

    Directory of Open Access Journals (Sweden)

    José E. García

    2014-01-01

    Full Text Available En 1987 los psicólogos estadounidenses James O. Whittaker y Sandra J. Whittaker publicaron la cuarta edición de su famoso libro Psicología. Este fue uno de los textos de introducción más conocidos y utilizados en América Latina y a través de él muchos miles de estudiantes aprendieron sus primeros conceptos sobre la psicología. Esta edición estaba preparada especialmente para su utilización con los alumnos de habla castellana e introducía numerosos tópicos relacionados a la psicología latinoamericana. Además incluía menciones específicas a algunos psicólogos de la región y sus contribuciones a la psicología. Uno de ellos era José de Jesús Aguirre, psicólogo y sacerdote jesuita y uno de los pioneros de la psicología profesional en el Paraguay. Aguirre aplicó la teoría del filósofo holandés Gerard Heymans y su colaborador el psiquiatra Enno Dirk Wiersma con las modificaciones que unos años más tarde introdujo el psicólogo francés René Le Senne. El propósito de la investigación era el análisis de los rasgos tipológicos característicos en la población paraguaya. Con ello, Aguirre iniciaba el estudio científico de la personalidad en el Paraguay. Este artículo estudia la importancia que corresponde asignar a la investigación de Aguirre como parte del texto introductorio de Whittaker y Whittaker. Se analizan los fundamentos teóricos de la tipología de Heymans-Wiersma-Le Senne y las adaptaciones realizadas por Aguirre, además de su aplicación a una muestra superior a las setecientas personas. Esta provenía de diversos niveles educativos, tanto secundarios como universitarios. En la parte concluyente se analiza la relevancia de Aguirre y su trabajo en el contexto de la psicología paraguaya y latinoamericana.

  13. Metafora i (giperëkstensija

    Directory of Open Access Journals (Sweden)

    Radić Jovanka

    2008-01-01

    Full Text Available (ruski Termin 'ëkstensija' imeet gorazdo bolee opredelennoe značenie po sravneniju s terminom metafora: ëkstensija podrazumevaet sposobnost' vyraženija (obyčno leksičeski zavisimogo slova k rasšireniju i vyraženiju svojstv predmetov, kotorye nastol'ko različny po svoej prirode, čto isključena vsjakaja vozmožnost' podobija ljubogo iz ih svojstv (ide čovek, ~ paun, ~ lav, ~ ekser, ~ voda; meka maca, ~ igračka, ~ bunda, meke papuče meko krzno, meka kruška, ~ voda, i t. p. Ëkstensija, v ukazannom značenii svjazana s giperëkstensiej, a takže s metaforoj ne po analogii, t. e. s pervymi tremja 'vidami' metafory, vydelennymi v 'Poëtike' Aristotelja ('perenesenie naimenovanija s odnogo predmeta na drugoj, pričem ili s roda na vid, ili s vida na rod, ili s vida na vid'. Različie meždu (1 poëtičeskoj metaforoj ('ukrašenie', 'stilističeskaja figura', zamečaemoj potomu, čto ona osnovyvaetsja na sbliženii dvuh ponjatij po analogii i tem samym 'soobščaet novoe znanie' ili 'živo predstavljaet vešč'', i (2 metaforoj ne po analogii t. e. perenosom naimenovanija, kotoryj neograničenno i nezametno rasširjaetsja, t. k. on ne osnovan na ustanovlenii svjazej po analogii meždu predmetami (ponjatijnaja metafora - aspekt, kotoryj do nedavnego vremeni vključalsja v termin polisemija, - možno dostatočno točno oboznačit' pri pomošči terminov intensivnaja i ëkstensivnaja metafora, sostavljajuščih oppoziciju. Takim obrazom, možno govorit' ob ëkstensivnoj metafore, kotoraja razvivaetsja v širinu i nezametna, i ob intensivnoj metafore, kotoraja zamečaetsja, t. k. razvivaetsja ne v širinu, a v glubinu.

  14. Mineral reactions and strain localization in a sheared mafic granulite infiltrated by melt (Seiland Igneous Province, Norway)

    Science.gov (United States)

    degli Alessandrini, Giulia; Menegon, Luca; Malaspina, Nadia; Dijkstra, Arjan; Anderson, Mark

    2016-04-01

    This study investigates the deformation mechanisms of a metagabbroic dyke experiencing syn-kinematic melt-rock interaction in a continental lower-crustal shear zone in the Seiland Igneous Province (northern Norway). Solid state shearing occurred at T ≈750-820 °C, P ≈0.75-0.95 GPa and was coeval with melt infiltration from dehydration melting of adjacent metasediments, as evident from thin leucosome veinlets within the dykes. The mylonite consists of cpx [Ca0.47,Mg0.35,Fe0.18]SiO3 + opx [Ca0.1,Mg0.5,Fe0.4]SiO3 + pl (An77Ab22Or1) porphyroclasts with localized grt and ilm coronas, embedded in a fine grained matrix of cpx + opx + pl + qtz + ilm ± kfs. Porphyroclasts range in size (diameter) between 25 to 650 μm, whereas the fine grain matrix is consistently below 10 μm (average 4-7 μm). Porphyroclasts show varying degrees of elongation, with the opx reaching aspect ratios of 1:16 and the cpx reaching rare maxima of 1:7. Cpx and pl porphyroclasts are micro-fractured and micro-boudinaged with fine-grained material infill. Texturally, opx porphyroclasts display a marked crystallographic preferred orientation (CPO) and activity of the {100} and minor {100} slip systems, whereas cpx and pl porphyroclasts are randomly oriented. All porphyroclasts have strong internal misorientations (undulatory and sweeping extinction) and lack recovery features (subgrains). The fine-grained polyphase matrix wrapping the porphyroclasts displays weak to absent CPO, with the exception of opx that shows a {100} poles-to-planes maxima perpendicular to the foliation. Based on the microstructure, we argue that a large part of the matrix is the product of metamorphic reactions in the presence of melt. To test this hypothesis, the interaction between the studied mafic dyke and an adjacent felsic leucosome was modelled using PerpleX for P-T conditions ranging between 7-9 kbar and 700-1000°C. Results show that the syn-kinematic mineral assemblage (opx + cpx + pl + qtz + ilm ± kfs) can be

  15. Using Low-Cost Iron-Based Materials as Oxygen Carriers for Chemical Looping Combustion Utilisation de matériaux bon marché à base de fer comme transporteur d’oxygène dans la combustion en boucle chimique

    Directory of Open Access Journals (Sweden)

    Jerndal E.

    2011-03-01

    matériaux, on trouve des oxydes en copeaux provenant de Sandvik et Scana, et un minerai de fer de LKAB. Tous les matériaux testés ont permis d’atteindre des conversions plus élevées sur gaz de synthèse que le matériau de référence (ilménite utilisé au cours de l’étude. D’une manière générale, les transporteurs d’oxygène les moins résistants, sans doute les plus poreux, sont les plus réactifs avec le gaz de synthèse. Le taux de conversion du CO obtenu avec ces matériaux est toujours plus élevé qu’avec l’ilménite. Le taux de conversion de l’hydrogène est plus élevé lorsque la durée de réduction augmente. Le matériau Sandvik 2 a permis d’atteindre les taux de conversion les plus importants sur gaz de synthèse et a donc été sélectionné pour des tests sur charge solide. Le taux de conversion sur charge solide avec ce matériau est plus élevé qu’avec l’ilménite.

  16. Two cryptic anatectic events within a syn-collisional granitoid from the Araçuaí orogen (southeastern Brazil): Evidence from the polymetamorphic Carlos Chagas batholith

    Science.gov (United States)

    Melo, M. G.; Stevens, G.; Lana, C.; Pedrosa-Soares, A. C.; Frei, D.; Alkmim, F. F.; Alkmin, L. A.

    2017-04-01

    From the earliest (ca. 630 Ma) pre-collisional plutons to the latest (ca. 480 Ma) post-collisional intrusions, the Araçuaí orogen (SE Brazil) records an outstanding succession of granite production events in space and time. The Carlos Chagas batholith (CCB) is the largest ( 14,000 km2) granitic body ascribed to the collisional plutonism (G2 supersuite) in the back-arc region of the Araçuaí orogen, to the east of the Rio Doce magmatic arc. A wide range of monazite and zircon ages (> 725 Ma to ca. 490 Ma) have been found in CCB granites, recording a rich history of crustal recycling and inheritance, magmatic crystallization and anatexis. The CCB includes a dominant granite richer in garnet than in biotite, in which three mineral assemblages can be identified: 1) Qz + Pl + Kfs + Bt + Grt + Ilm ± Rt; 2) Qz + Pl + Kfs + Bt + Grt + Ilm + Sil; and 3) Qz + Pl + Kfs + Bt + Grt + Ilm + Sil + Spl. Rocks which contain mineral assemblage 2 and 3 all contain two generations of garnet. Textural evidence for the presence of former melt, recognized in all studied CCB samples, includes: silicate melt inclusions in poikiloblastic garnet, pseudomorphed thin films of melt surrounding both generations of garnet, pseudomorphed melt pools adjacent to garnet and biotite, and plagioclase and quartz with cuspate-lobate shapes occurring among matrix grains. Both generations of garnet crystals (Grt1 and Grt2) are unzoned in terms of major element concentration, contain small rounded inclusions of Ti-rich biotite and, in addition, the Grt2 crystals also contain inclusions of remnant sillimanite needles. Microstructural evidence, in combination with mineral chemistry, indicates that the garnet crystals grew during two distinct metamorphic-anatectic events, as the peritectic products of fluid-absent melting reactions which consumed biotite, quartz and plagioclase, in the case of Grt1, and which consumed biotite, quartz, plagioclase and sillimanite in the case of Grt2. P-T pseudosections

  17. Sedimentary processes and depositional environments of the Horn River Shale in British Columbia, Canada

    Science.gov (United States)

    Yoon, Seok-Hoon; Koh, Chang-Seong; Joe, Young-Jin; Woo, Ju-Hwan; Lee, Hyun-Suk

    2017-04-01

    The Horn River Basin in the northeastern British Columbia, Canada, is one of the largest unconventional gas accumulations in North America. It consists mainly of Devonian shales (Horn River Formation) and is stratigraphically divided into three members, the Muskwa, Otterpark and Evie in descending order. This study focuses on sedimentary processes and depositional environments of the Horn River shale based on sedimentary facies analysis aided by well-log mineralogy (ECS) and total organic carbon (TOC) data. The shale formation consists dominantly of siliceous minerals (quartz, feldspar and mica) and subordinate clay mineral and carbonate materials, and TOC ranging from 1.0 to 7.6%. Based on sedimentary structures and micro texture, three sedimentary facies were classified: homogeneous mudstone (HM), indistinctly laminated mudstone (ILM), and planar laminated mudstone (PLM). Integrated interpretation of the sedimentary facies, lithology and TOC suggests that depositional environment of the Horn River shale was an anoxic quiescent basin plain and base-of-slope off carbonate platform or reef. In this deeper marine setting, organic-rich facies HM and ILM, dominant in the Muskwa (the upper part of the Horn River Formation) and Evie (the lower part of the Horn River Formation) members, may have been emplaced by pelagic to hemipelagic sedimentation on the anoxic sea floor with infrequent effects of low-density gravity flows (turbidity currents or nepheloid flows). In the other hand, facies PLM typifying the Otterpark Member (the middle part of the Horn River Formation) suggests more frequent inflow of bottom-hugging turbidity currents punctuating the hemipelagic settling of the background sedimentation process. The stratigraphic change of sedimentary facies and TOC content in the Horn River Formation is most appropriately interpreted to have been caused by the relative sea-level change, that is, lower TOC and frequent signal of turbidity current during the sea

  18. The self-reversal origin of the reversed remanent magnetization in the igneous rocks containing the oxidized Fe-Ti oxide solid solutions

    Science.gov (United States)

    Orlický, Oto

    2011-01-01

    I study the magnetic and paleomagnetic characteristics of the Pleistocene to Quaternary basalts from the West Carpathian Mountains. I have revealed the existence of the so-called self-reversal remanent magnetization bearing disordered-antiferromagnetic Fe-Ti phases, with the Néel temperatures of either TN = 430-450 °C (the Ti-Mgh phases) or with TN = 460-470 °C (Hem-Ilm phases). I have suggested for the first time to name of these phases in this article. It is very important that these phases are the only sources of the reversed RM, of the self-reversal origin, probably of the chemical remanent magnetization (CRM) origin. The basalts of Southern Slovakia were differentiated to these of the magnetite and Ti-rich Ti-Mt bearing rocks with normal polarity of RM, and those with the presence of the self-reversal RM bearing disordered-antiferromagnetic Ti-Mgh phases of the TN = 430 to 450 °C, and those of the disordered-antiferromagnetic Hem-Ilm phases of the TN = 460 - 470 °C, both of only reversed RM of the self-reversal origin. I present the original model based on the principe that the magnetite, hematite and Ti-rich titanomagnetite bearing rocks, without any disordered-antiferromagnetic phases, carry only normal - positive RM. The self-reversal remanent magnetization bearing disordered-antiferromagnetic magnetic phases of Fe-Ti oxide solid solutions carry only reversed remanent magnetization in the rocks. This model has been involved to explain the reversed or normal RM of submarine igneous rocks published in the literature. We anticipate that in all continental or submarine reversally magnetized rocks the disordered-antiferromagnetic Fe-Ti phases would be revealed, either in their initial, complete developed stages, or as the remnants of these phases. We suggest that the reverse remanent magnetization of rocks is due to the existence of the self-reversal remanent magnetization bearing disordered-antiferromagnetic magnetic phases of Fe-Ti solid solutions in the

  19. Visual acuity loss associated with excessive “dry macula” in exudative age-related macular degeneration

    Directory of Open Access Journals (Sweden)

    Takahashi H

    2018-02-01

    Full Text Available Hidenori Takahashi,1–3 Yuji Inoue,1,2 Xue Tan,2,3 Satoru Inoda,1 Shinichi Sakamoto,1 Yusuke Arai,1 Yasuo Yanagi,4–6 Yujiro Fujino,2,3 Hidetoshi Kawashima1 1Department of Ophthalmology, Jichi Medical University, Shimotsuke, 2Department of Ophthalmology, The University of Tokyo, Bunkyo, 3Department of Ophthalmology, Japan Community Health Care Organization Tokyo Shinjuku Medical Center, Shinjuku, Japan; 4Medical Retina, Singapore National Eye Centre, 5Medical Retina, Singapore Eye Research Institute, 6Eye-ACP, Duke NUS Medical School, National University of Singapore, Singapore Purpose: To investigate the correlation between visual acuity and central macular thickness (CMT and choroidal thickness (CCT in patients with wet age-related macular degeneration (AMD. Methods: In this retrospective analysis, 14 eyes that received >10 ranibizumab injections (based on pro re nata [PRN] regimen and maintained initial visual acuity gain were analyzed. The following 5 parameters were measured at the foveal center: CMT (distance from the inner limiting membrane [ILM] to Bruch’s membrane; central retinal thickness (CRT; distance from the ILM to the inner limit of the retinal pigment epithelium or subretinal fluid [SRF]; SRF thickness (SRFT; pigment epithelium detachment thickness (PEDT; and CCT. The correlation between the logarithm of the minimum angle of resolution (logMAR best-corrected visual acuity (BCVA and the 5 parameters was examined with generalized estimating equations. Results: CMT, CRT, and CCT were negatively correlated with logMAR BCVA (P=0.031, 0.023, and 0.036, respectively when only CMT values less than the thickness that maximized visual acuity for each eye were used for the analysis. Each 100-µm reduction in CMT, CRT, or CCT improved logMAR BCVA by -0.1, -0.08, or -0.07, respectively. SRFT and PEDT were not correlated with BCVA. The median CMT that maximized the visual acuity was 230 µm. Conclusion: Dry macula with CMT <230 µm was

  20. Atık Alüminyum Polietilen (Tetrapak ve Pirinç Sapı Kullanılarak Üretilen Ahşap Polimer Kompozitlerin Mekanik Davranışlarının Belirlenmesi

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    Alperen KAYMAKCI

    2012-12-01

    Full Text Available ÖzetBu çalışmada pirinç sapı unu ile güçlendirilmiş alüminyum polietilen esaslı polimer kompozitlerin bazı mekanik özellikleri araştırılmıştır. Bu amaç doğrultusunda pirinç sapı unu, alüminyum polietilen ve uyum sağlayıcı ajan (MAPE ikiz vidalı bir ekstruder içerisinde karıştırılarak pellet elde edilmiştir. Elde edilen pelletler enjeksiyon kalıplama makinesi kullanılarak mekanik özellikleri belirlemek için gerekli olan numunelerin üretimi sağlanmıştır. Pirinç sapı unu miktarının artmasıyla üretilen alüminyum polietilen esaslı polimer kompozitlerin eğilme ve çekme modüllerinde artış olduğu belirlenmiştir ancak eğilme ve çekme direnci değerlerinde bir miktar azalma tespit edilmiştir. Alüminyum polietilen esaslı polimer kompozit üretiminde kullanılan maleik anhidrit polietilen uyum sağlayıcı ajanın mekanik özellikleri üzerine olumlu etki yaptığı belirlenmiştir. Bu çalışmayla maleik anhidrit polietilen ile muamele edilen alüminyum esaslı polietilen kompozitlerin kabul edilebilir mekanik özellikleri dolayısıyla taban döşeme malzemesi olarak kullanılabileceği belirtilmiştir.AbstractIn this study, we evaluated some mechanical properties of aluminum polyethylene (Tetra Pak composites reinforced with rice husk flour. To meet this objective, rice husk flour was compounded with aluminum polyethylene with coupling agent (MAPE in a twin screw co-rotating extruder and then was manufactured by injection molding process. The modulus in the flexural and tensile improved with increasing rice husk flour content while the tensile and flexural strengths of the samples decreased. The use of maleic anhydride polyethylene had a positive effect on the mechanical properties of the aluminum polyethylene composites reinforced with rice husk flour. This work showed that the composites treated with maleated polyethylene could be efficiently used as decking products, due to satisfactory

  1. A Role for Prefrontal Cortical NMDA Receptors in Murine Alcohol-Heightened Aggression.

    Science.gov (United States)

    Newman, Emily L; Terunuma, Miho; Wang, Tiffany L; Hewage, Nishani; Bicakci, Matthew B; Moss, Stephen J; DeBold, Joseph F; Miczek, Klaus A

    2017-10-20

    Alcohol is associated with nearly half of all violent crimes committed in the United States; yet, a potential neural basis for this type of pathological aggression remains elusive. Alcohol may act on N-methyl-d-aspartate receptors (NMDARs) within cortical circuits to impede processing and to promote aggression. Here, male mice were characterized as alcohol-heightened (AHAs) or alcohol non-heightened aggressors (ANAs) during resident-intruder confrontations after self-administering 1.0 g/kg alcohol (6% w/v) or water. Alcohol produced a pathological-like pattern of aggression in AHAs; these mice shifted their bites to more vulnerable locations on the body of a submissive animal, including the anterior back and ventrum after consuming alcohol. In addition, through immunoblotting, we found that AHAs overexpressed the NMDAR GluN2D subunit in the prefrontal cortex (PFC) as compared to ANAs while the two phenotypes expressed similar levels of GluN1, GluN2A and GluN2B. After identifying several behavioral and molecular characteristics that distinguish AHAs from ANAs, we tested additional mice for their aggression following preferential antagonism of GluN2D-containing NMDARs. In these experiments, groups of AHAs and ANAs self-administered 1.0 g/kg alcohol (6% w/v) or water before receiving intraperitoneal (i.p.) doses of ketamine or memantine, or infusions of memantine directly into the prelimbic (PLmPFC) or infralimbic medial PFC (ILmPFC). Moderate doses of IP ketamine, IP memantine, or intra-PLmPFC memantine increased aggression in AHAs, but only in the absence of alcohol. Prior alcohol intake blocked the pro-aggressive effects of ketamine or memantine. In contrast, only memantine, administered systemically or intra-PLmPFC, interacted with prior alcohol intake to escalate aggression in ANAs. Intra-ILmPFC memantine had no effect on aggression in either AHAs or ANAs. In sum, this work illustrates a potential role of GluN2D-containing NMDARs in the PLmPFC in alcohol

  2. Quantifying metamorphopsia with M-CHARTS in patients with idiopathic macular hole

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    Wada I

    2017-09-01

    Full Text Available Iori Wada, Shigeo Yoshida, Yoshiyuki Kobayashi, Yedi Zhou, Keijiro Ishikawa, Shintaro Nakao, Toshio Hisatomi, Yasuhiro Ikeda, Tatsuro Ishibashi, Koh-hei Sonoda Department of Ophthalmology, Kyushu University Graduate School of Medical Sciences, Fukuoka, Japan Purpose: The purpose of this study was to determine the degree of metamorphopsia using M-CHARTS™ in patients with idiopathic macular hole before and after pars plana vitrectomy and internal limiting membrane (ILM peeling. Patients and methods: The records of 22 eyes of 22 patients with a full-thickness macular hole who underwent pars plana vitrectomy and ILM peeling were reviewed. All patients underwent a complete ophthalmic examination including spectral-domain optical coherence tomography (OCT. Horizontal metamorphopsia (MH and vertical metamorphopsia (MV scores were determined using M-CHARTS at the same time. The time course of changes in metamorphopsia and the relationship between best-corrected visual acuity (BCVA and OCT parameters were assessed. Results: Sealing of the macular hole was noted in all eyes after surgery. BCVA improved significantly from 1 month after surgery (P<0.001. The MV score was significantly higher than the MH score before surgery (P<0.05 and improved significantly from 1 month after surgery (P<0.03. The MH score improved significantly at 6 months after surgery (P<0.001. The postoperative MV and MH scores became closer to one another from 1 month after surgery. Moreover, the MV score was higher than the MH score at all postoperative assessments. There was a significant correlation between the MV and MH scores at all follow-up assessments. There was no significant correlation between BCVA and the MV or MH score at any follow-up assessment. Conclusion: The satisfaction of the patients with macular hole after surgery cannot be necessarily measured by BCVA alone, because M-scores were not correlated to BCVA in postoperative evaluation. Therefore, evaluation of

  3. Great Basin Integrated Landscape Monitoring Pilot Summary Report

    Science.gov (United States)

    Finn, Sean P.; Kitchell, Kate; Baer, Lori Anne; Bedford, David R.; Brooks, Matthew L.; Flint, Alan L.; Flint, Lorraine E.; Matchett, J.R.; Mathie, Amy; Miller, David M.; Pilliod, David S.; Torregrosa, Alicia; Woodward, Andrea

    2010-01-01

    The Great Basin Integrated Landscape Monitoring Pilot project (GBILM) was one of four regional pilots to implement the U.S. Geological Survey (USGS) Science Thrust on Integrated Landscape Monitoring (ILM) whose goal was to observe, understand, and predict landscape change and its implications on natural resources at multiple spatial and temporal scales and address priority natural resource management and policy issues. The Great Basin is undergoing rapid environmental change stemming from interactions among global climate trends, increasing human populations, expanding and accelerating land and water uses, invasive species, and altered fire regimes. GBLIM tested concepts and developed tools to store and analyze monitoring data, understand change at multiple scales, and forecast landscape change. The GBILM endeavored to develop and test a landscape-level monitoring approach in the Great Basin that integrates USGS disciplines, addresses priority management questions, catalogs and uses existing monitoring data, evaluates change at multiple scales, and contributes to development of regional monitoring strategies. GBILM functioned as an integrative team from 2005 to 2010, producing more than 35 science and data management products that addressed pressing ecosystem drivers and resource management agency needs in the region. This report summarizes the approaches and methods of this interdisciplinary effort, identifies and describes the products generated, and provides lessons learned during the project.

  4. Spatial Temporal Modelling of Particulate Matter for Health Effects Studies

    Science.gov (United States)

    Hamm, N. A. S.

    2016-10-01

    Epidemiological studies of the health effects of air pollution require estimation of individual exposure. It is not possible to obtain measurements at all relevant locations so it is necessary to predict at these space-time locations, either on the basis of dispersion from emission sources or by interpolating observations. This study used data obtained from a low-cost sensor network of 32 air quality monitoring stations in the Dutch city of Eindhoven, which make up the ILM (innovative air (quality) measurement system). These stations currently provide PM10 and PM2.5 (particulate matter less than 10 and 2.5 m in diameter), aggregated to hourly means. The data provide an unprecedented level of spatial and temporal detail for a city of this size. Despite these benefits the time series of measurements is characterized by missing values and noisy values. In this paper a space-time analysis is presented that is based on a dynamic model for the temporal component and a Gaussian process geostatistical for the spatial component. Spatial-temporal variability was dominated by the temporal component, although the spatial variability was also substantial. The model delivered accurate predictions for both isolated missing values and 24-hour periods of missing values (RMSE = 1.4 μg m-3 and 1.8 μg m-3 respectively). Outliers could be detected by comparison to the 95% prediction interval. The model shows promise for predicting missing values, outlier detection and for mapping to support health impact studies.

  5. Multifrequency and edge breathers in the discrete sine-Gordon system via subharmonic driving: Theory, computation and experiment

    Energy Technology Data Exchange (ETDEWEB)

    Palmero, F. [Grupo de Física No Lineal, Departamento de Física Aplicada I, ETSI Informática, Universidad de Sevilla, Avda. Reina Mercedes, s/n, 41012 Sevilla (Spain); Department of Physics and Astronomy, Dickinson College, Carlisle, PA 17013 (United States); Han, J. [Department of Physics and Astronomy, Dickinson College, Carlisle, PA 17013 (United States); English, L.Q., E-mail: englishl@dickinson.edu [Department of Physics and Astronomy, Dickinson College, Carlisle, PA 17013 (United States); Alexander, T.J. [School of Physical, Environmental and Mathematical Sciences, UNSW Canberra, 2610 (Australia); Kevrekidis, P.G. [Department of Mathematics and Statistics, University of Massachusetts, Amherst, MA 01003-4515 (United States); Center for Nonlinear Studies and Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM 87544 (United States)

    2016-01-28

    We consider a chain of torsionally-coupled, planar pendula shaken horizontally by an external sinusoidal driver. It has been known that in such a system, theoretically modeled by the discrete sine-Gordon equation, intrinsic localized modes, also known as discrete breathers, can exist. Recently, the existence of multifrequency breathers via subharmonic driving has been theoretically proposed and numerically illustrated by Xu et al. (2014) [21]. In this paper, we verify this prediction experimentally. Comparison of the experimental results to numerical simulations with realistic system parameters (including a Floquet stability analysis), and wherever possible to analytical results (e.g. for the subharmonic response of the single driven–damped pendulum), yields good agreement. Finally, we report the period-1 and multifrequency edge breathers which are localized at the open boundaries of the chain, for which we have again found good agreement between experiments and numerical computations. - Highlights: • We have confirmed experimentally the existence of subharmonic ILM/breather structures in a chain of coupled torsion pendula. • Experiments are in line with our theoretical analysis and numerical computations. • We have also revealed surface breather modes in this chain, both experimentally and numerically.

  6. White Centered Retinal Hemorrhages in Vitamin B12 Deficiency Anemia

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    Claus Zehetner

    2011-05-01

    Full Text Available Background: To report a case of severe vitamin B12 deficiency anemia presenting with white centered retinal hemorrhages. Methods: Interventional case report. Results: A 40-year-old man, general practitioner himself, presented with a 1-day history of diminished left visual acuity and a drop-shaped central scotoma. The corrected visual acuities were 20/20, OD and 20/100, OS. Ophthalmic examination revealed bilaterally pale tarsal conjunctiva, discretely icteric bulbar conjunctiva and disseminated white centered intraretinal hemorrhages with foveal involvement. OCT imaging through these lesions revealed a retinal thickening caused by a sub-ILM accumulation of hyperreflective and inhomogeneous deposits within the nerve fiber layer. Immediate laboratory work-up showed severe megaloblastic anemia caused by vitamin B12 deficiency requiring erythrocyte transfusions. Discussion: Most reports of white centered retinal hemorrhages have been described in patients with leukemic retinopathy and bacterial endocarditis. It is interesting that this case of vitamin B12 deficiency anemia retinopathy has a clinically indistinguishable fundus appearance. This is probably due to the common pathology of capillary disruption and subsequent hemostatic fibrin plug formation. In megaloblastic anemia, direct anoxia results in endothelial dysfunction. The loss of impermeability allows extrusion of whole blood and subsequent diffusion from the disrupted site throughout and above the nerve fiber layer. Therefore the biomicroscopic pattern of white centered hemorrhages observed in anemic retinopathy is most likely due to the clot formation as the reparative sequence after capillary rupture.

  7. Kunstisuvi 2008, teine osa / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2008-01-01

    Sirje Runge tööde näitus Eesti Panga galeriis. Aneri Kärkkäineni ja Elis Saarevälja näitus "Sad Sack" ArtDepoo galeriis. Nadezhda Tshernobai "Kollase süütuse suudlus", Ilme Rätsepa kangamaalid "Kolmainsus" ning Kadri Kangilaski ja Toomas Tõnissoo maalinäitus "Perekonnaelu" Draakoni galeriis. Kati Kerstna ja Kairi Orgusaare "Läbivaade" Tallinna Kunstihoone galeriis. Mare Saare "Fragiilid" ja Alice Kase tööd Hobusepea galeriis. Ulvi Haagenseni "Antipoodid" HOP galeriis. Alvar Reisneri "Extra & Ordinary" Vaal-galeriis. Liisi Eelmaa videoinstallatsioon-aktsioon "Õnnekeeks" (11. VII), Minna Hindi interaktiivne installatsioon "Ainult täna õhtul: Minna Hint" (18. VII), Sirli Heina maal "Kirsitort" (16. VII) Artishoki näitusel Tallinna Linnagaleriis. Ado Lille "Nude alive" Haus galeriis. Toomas Altnurme "Metafüüsika seitsmes dimensioon" SEBi galeriis. 5. VII toimunud kunstinädala "Kultuurikatapuldid 2008" üritused (esinejad: Linnar Priimägi, Jüri Ojaver, Erik Alalooga, Siim-Tanel Annus, E. Saareväli, Jaan Toomik, Kiwa) Haapsalus

  8. Inkâr al-Sunnah pada Aspek Kodifikasi Hadis

    Directory of Open Access Journals (Sweden)

    Zainuddin Mz

    2015-09-01

    Full Text Available One aspect that makes a bunch of people does not believe in the existence and role of sunnah is the delay of codification itself. Peoples also considered that hadith’s codified in various references are not what are worth ascribed to the Prophet, but rather a form of the companions comprehension of the Prophet’s directives and statements. That is why, there are different editorial ranges between one companion to another, even the mutawâtir lafzî was not separated from this editorial differences. This paper high lights how was the process of hadith codification, so that we can find a common points which are closely related to the authenticity and validity of a hadith. Studying on such topic (the process of hadith codification and classification, shows how professional the hadith scholars in memorizing and maintaining Sunnah of the Prophet, to bring the science of isnâd (‘ilm al-isnâd which is never possessed by any other religion. This is the climax of the way clergy maintaining the authenticity of the Prophet sayings. That is, whenever one states todays about a hadith, definitely, its authenticity and validity would be detected through the scienc.

  9. Fundus auto fluorescence and spectral domain ocular coherence tomography in the early detection of chloroquine retinopathy

    Directory of Open Access Journals (Sweden)

    Megan B. Goodman

    2015-08-01

    Full Text Available Purpose: To determine the sensitivity of spectral domain ocular coherence tomography (SD-OCT and fundus auto fluorescence (FAF images as a screening test to detect early changes in the retina prior to the onset of chloroquine retinopathy. Method: The study was conducted using patients taking chloroquine (CQ, referred by the Rheumatology Department to the Ophthalmology Department at Tygerberg Academic Hospital. Group A consisted of 59 patients on CQ for less than 5 years, and Group B consisted of 53 patients on CQ for more than 5 years. A 200 × 200 macula thickness map, 5-line raster SD-OCT on a Carl Zeiss Meditec Cirrus HD-OCT and FAF images on a Carl Zeiss Meditec Visucam 500 were recorded for 223 eyes. Images were reviewed independently, and then those of Groups A and B compared. Results: There were no statistically significant differences between Groups A and B. The criteria included the internal limiting membrane and the retinal pigment epithelium (ILM-RPE thickness, interdigitation zone integrity (p = 0.891, df = 1, χ² = 0.1876, ellipsoid zone integrity (p = 0.095, df = 2, χ² = 4.699 and FAF image irregularities (p = 0.479, df = 1, χ²= 4995978. Conclusion: The inclusion of SD-OCT and FAF as objective tests into the prescribed screening guidelines does not appear to simplify the detection of subclinical injury in patients on chloroquine treatment.

  10. LAFAZH DAN MAKNA DALAM PERSPEKTIF PEMIKIRAN LINGUISTIK IBN JINNI

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    Wati Susiawati

    2015-12-01

    Full Text Available Based on the readings and content analysis (tahlîl al-muhtawa of Ibn Jinni’s book, al-khashâish and the other works related to linguistic thought, it was found that the notion of linguistic Ibn Jinni about the utterances and meaning are in the area of macro-linguistics that can not be separated from the study of phonology, morphology , syntax, and semantic. In addition, it cannot be separated from one another, utterances and meaning in Arabic, according to Ibn Jinni, it is used and developed as a medium of communication, both spoken and written. Therefore, word and meaning must be understood in the process, the events and the context of linguistic and socio-cultural context as a whole. Word and meaning of the object of study is the linguistic multiperspective, thus giving birth to the various fields of linguistic science. Linguistic thought about the word and meaning is important not only serve as a theoretical basis for understanding the text in Arabic, but also significantly to the development of learning 'ilm al-dalâlah (semantics to the Arabic leaner or scholar.DOI: 10.15408/a.v2i2.2133

  11. Hip and pelvis diseases on lumbar AP radiographs including both hip joints

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Hyun Soo; Juhng, Seon Kwan; Kim, Eun A; Kim, Jeong Ho; Song, Ha Heon; Shim, Dae Moo [Wonkwang University School of Medicine, Iksan (Korea, Republic of)

    2002-12-01

    To determine the frequency of disease, and to evaluate the methods used for lumbar spine radiography in Korea. Sixty university and training hospitals were randomly selected and asked to describe the projections, film size and radiographic techniques employed for routine radiography in patients with suspected disease of the lumbar spine. Plain radiographs of 1215 patients, taken using 14x17 inch film and depicting both hip joints and the lumbar region, were analysed between March 1999 and February 2000. In 15 patients (1.2%), the radiographs revealed hip or pelvic lesion, confirmed as follows: avascular necrosis of the femoral head (n=11, with bilateral lesion in four cases); sustained ankylosing spondylitis (n=2); acetabular dysplasia (n=1); and insufficiency fracture of the pubic rami secondary to osteoporosis (n=1). In 11 or the 20 hospitals which responded, 14{sup x}17{sup f}ilm was being used for lumbar radiography, while in the other nine, film size was smaller. Plain radiography of the lumbar spine including both hip joints, may be a useful way to simultaneously evaluate lesions not only of the lumbar spine but also of the hip and/or pelvis.

  12. Data-based online nonlinear extremum-seeker for wavefront sensorless adaptive optics OCT (Conference Presentation)

    Science.gov (United States)

    Jian, Yifan; Verstraete, Hans R. G. W.; Heisler, Morgan; Ju, Myeong Jin; Wahl, Daniel J.; Bliek, Laurens; Kalkman, Jeroen; Bonora, Stefano; Verhaegen, Michel; Sarunic, Marinko V.

    2017-02-01

    Adaptive optics has been successfully applied to cellular resolution imaging of the retina, enabling visualization of the characteristic mosaic patterns of the outer retina. Wavefront sensorless adaptive optics (WSAO) is a novel technique that facilitates high resolution ophthalmic imaging; it replaces the Hartmann-Shack Wavefront Sensor with an image-driven optimization algorithm and mitigates some the challenges encountered with sensor-based designs. However, WSAO generally requires longer time to perform aberrations correction than the conventional closed-loop adaptive optics. When used for in vivo retinal imaging applications, motion artifacts during the WSAO optimization process will affect the quality of the aberration correction. A faster converging optimization scheme needs to be developed to account for rapid temporal variation of the wavefront and continuously apply corrections. In this project, we investigate the Databased Online Nonlinear Extremum-seeker (DONE), a novel non-linear multivariate optimization algorithm in combination with in vivo human WSAO OCT imaging. We also report both hardware and software updates of our compact lens based WSAO 1060nm swept source OCT human retinal imaging system, including real time retinal layer segmentation and tracking (ILM and RPE), hysteresis correction for the multi-actuator adaptive lens, precise synchronization control for the 200kHz laser source, and a zoom lens unit for rapid switching of the field of view. Cross sectional images of the retinal layers and en face images of the cone photoreceptor mosaic acquired in vivo from research volunteers before and after WSAO optimization are presented.

  13. Repeat gas insufflation for successful closure of idiopathic macular hole following failed primary surgery

    Directory of Open Access Journals (Sweden)

    Pukhraj Rishi

    2014-01-01

    Full Text Available A 65-year-old lady presented with decreased vision in left eye since seven months. Vision was 6/9 in right eye and 6/36 in left. Examination revealed idiopathic, full-thickness macular hole in left eye; confirmed by optical coherence tomography (OCT. Patient underwent phacoemulsification with intraocular lens (IOL implantation, vitrectomy, internal limiting membrane (ILM peeling and 14% C 3 F 8 gas injection. OCT repeated after six weeks revealed type II closure with cuff of subretinal fluid. Four weeks later, patient underwent fluid-gas exchange with 14% C 3 F 8 gas and postoperative positioning. OCT was repeated after two weeks, which showed complete closure of the macular hole. OCT can help in selection of eyes for re-surgery that stand a better chance for hole closure. Macular holes with cuff of subretinal fluid are probably more likely to close on re-surgery than those without. However, larger studies with longer follow-up are required to validate this finding.

  14. Projecting Homes: Domestic Spaces in Three Filipino Films

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    Tito R. Quiling Jr.

    2013-12-01

    Full Text Available The house is a fundamental space for a character’s consciousness, and this structure is a familiar image in Filipino f ilms. This particular space as a setting in which the narrative and the characters are able to move in, is essential. This paper analyzes the influence of domestic spaces and the characteristics of home, which correspond to the characters’ consciousness and the narrative. These are presented in the selected films: Oro, Plata, Mata (1982 by Peque Gallaga, “Hellow, Soldier,” the second episode in Lino Brocka’s Tatlo, Dalawa, Isa (1975, and Kisapmata (1981 by Mike De Leon. The method for assessment consists of three parts: (1 the background in which the films are set, (2 the influence of the house using Gaston Bachelard’s notion of the house in The Poetics of Space (1994 as a framework, (3 and the behavior of the characters as portrayed in the films. The significance of domestic spaces to a character’s experience is illustrated in the selected texts.

  15. Louis Massignon l'amour mystique ou l'extase dans l'abandon

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    Jacques Keryell

    2008-09-01

    Full Text Available Parler de Massignon et de son Amour de Dieu n'est pas chose aisée. En effet, si les mystiques musulmans des premiers siècles de l'hégire ont été les hérauts de cet Amour : Al-Hallâj, Râbia al-Adawiyya, Al-Niffâri, Ibn Arabi, Ansâri, Al-Ghazâli, l'Amour de Dieu comme tel, n'est pas au cœur du "ilm al kalâm", de la théologie musulmane traditionnelle. Pour Massignon, langue et spiritualité étaient intimement liées. Si je devais me placer dans une perspective musulmane, je dirais que Louis Massignon se situe dans la ligne de la "wahdat al shuhûd", celle de "l'unicité du témoignage" ou Dieu se témoigne Lui-même en son mystère dans le cœur du soufi.

  16. Magistritööde kaitsmine : [Kaja Tiisel jt.

    Index Scriptorium Estoniae

    1999-01-01

    3. veebr. '99 kaitses Kaja Tiisel TPÜ infoteaduste magistrikraadi kaitsmisnõukogus magistritööd "Tallinna Toomkooli raamatukogu arengulugu ning koostis"; 4. märtsil Uno Ilm TPÜ psühholoogia magistrikraadi kaitsmisnõukogus magistritööd "Süüdimõistetute kriminaalne subkultuur slängis ja tätoveeringutes"; 11. mail Katri Laurimaa TPÜ filoloogiateaduste magistrikraadi kaitsmisnõukogus magistritööd "Muinasjutu "Vahetatud naine" (AT 403B) eesti teisendid rahvusvahelises kontekstis" ja Julia Šamarina TPÜ filoloogiateaduste magistrikraadi kaitsmisnõukogus magistritööd "Sugupoolte küsimus Angela Carteri loomingus (Gender Issues in Angela Carters' Writing)"; 13. mail Tatjana Gramušnjak TPÜ matemaatika magistritööde kaitsmisnõukogus magistritööd "Positiivselt määratud ruutvormide C-tüüpide leidmise probleemidest"; 25. mail Ljudmila Dubjeva TPÜ infoteaduste osakonna magistrikraadi kaitsmisnõukogus magistritööd "Traditsiooniliste infosüsteemide kujunemine Tartu Ülikooli raamatukogus"; 26. mail Ülle Saarits TPÜ kasvatusteaduste ja pedagoogika magistrikraadi kaitsmisnõukogus magistritööd "Vanavanema roll linnaperekonnas : lapsevanema refleksioon" ja Enn Siim TPÜ kasvatusteaduste ja pedagoogika magistrikraadi kaitsmisnõukogus magistritööd "Isiksuse arengu põhimõte aktiivõppes (põhikooli algastmes)"

  17. PEMAHAMAN HADITS TARBAWI BURHAN AL ISLAM AL ZARNUJI DALAM KITAB TA’LIM AL MUTA’ALLIM

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    Benny Afwadzi

    2017-01-01

    Full Text Available This paper explores the understanding of tarbawi (education hadith from one of the major influential clerics in the Islamic educational system, especially in pesantren. He is Burhan al Islam al Zarnuji with his landmark book Ta’lim al Muta’allim. The conclusion that can be drawn is that al Zarnuji has shades of sufistical view in understanding tarbawi hadith. This can be seen in his understanding of hadith on obligation to seek knowledge (thalab al ilmi faridhatun ‘ala kulli muslimin wa muslimatin, which is interpreted as ilm al hal, the science concerning the condition of the human religious or simplistically said as the religious sciences; and the hadith of intention of studying (innama al a’malu bi al niyyat with the intention for the sake of the hereafter and religion, not mundane. Such an understanding is not something taken for granted, but it can be reinterpreted and perfected in accordance with the spirit of the times of context.

  18. Jaghmīnī’s Mulakhkhaṣ an Islamic introduction to Ptolemaic astronomy

    CERN Document Server

    Ragep, Sally P

    2016-01-01

    This book provides the only critical edition and English translation of Maḥmūd al-Jaghmīnī’s al-Mulakhkhaṣ fī al-hayʾa al-basīṭa, the most widely circulated Arabic treatise on Ptolemaic astronomy ever written. Composed in the early 13th century, this introductory textbook played a crucial role in the teaching, dissemination, and institutional instruction of Islamic astronomy well into the 19th century (and beyond). Establishing the base text is a fundamental prerequisite for gaining insights into what was considered an elementary astronomical textbook in Islam and also for understanding the extensive commentary tradition that built upon it. Within this volume, the Mulakhkhaṣ is situated within the broader context of the genre of literature termed ʿilm al-hayʾa, which has become the subject of intensive research over the past 25 years. In so doing, it provides a survey of summary accounts of theoretical astronomy of Jaghmīnī’s predecessors, both Ancient and Islamic, which could have serve...

  19. DOES SURŪRĮ HAVE A BOOK CALLED “AĤKĀM-I NÜCŪM”? / SURŪRĮ’NĐN AĤKĀM-I NÜCŪM ĐSĐMLĐ BIR ESERĐ VAR MI?

    Directory of Open Access Journals (Sweden)

    Dr. Hakan YAMAN

    2008-05-01

    Full Text Available One of the famous scientists of the Kanuni period, GeliboluluSururi, gained his reputation by his commentary-books and his translations.His commentaries to “Mesnevi” and “Sebistan-i Hayal” which made himfamous, his books in Arabic and Farsi and his translations from theselanguages can be mentioned as major parts of his work. Although it is notexactly known how many books he published, total number of his books areassumed to be around 30 including his translations and compilations. One ofhis translations was famous cosmology book of the time “Kitabü’l-aca’ibve’l-Gara’ib” by Kazvini. Although most of the sources about “Sururi” claimhim to author a book about “ilm-i nücum” (science of stars, the mentionedbook is unfortunately not available in any library. In this article we will try toverify whether Sururi really authored an astrology book, making use ofdependable sources available.

  20. PEMIKIRAN TAFSÎR MESIR MODERN J.J.G JANSEN (Telaah atas Karya J.J.G.Jansen The Interpretation of The Koran in Modern Egypt

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    Abu Bakar Abu Bakar

    2013-08-01

    Full Text Available Abstract: Jansen is a researcher that classifies the work of interpretation (tafsîr into: firstly, an interpretation adopting a modern science but not oppose against the holy Quran, it is called tafsîr  al-‘ilmî. Secondly, an interpretation that is designed to help reader understand the holy Quran or philological interpretation (al-tafsîr  al-lughawî. Thirdly, an interpretation dealing with the Muslim deed and it is called practical interpretation (tafsîr  al-adabî al-ijtimâ’î. Jansen is about to display a short description that covers the answers of explanation inadequacy of the previous researchers’ studies. He mainly clarifies  the history of interpretation and western studies on interpretation developing in Islamic world. As a matter of fact, Jansen’s view is majorly a kind of beginning critical of his attention on interpretation. He focuses the research object on the interpretation of Muhammad Abduh, then he compares it to the other intrepretations that are considered up to standard to be classified into his work of interpretation.   Key Words: al-Qur’ân, tafsîr, dan Jansen  

  1. Argon green-Nd: YAG dual laser posterior hyaloidotomy: An innovative approach toward treatment of premacular hemorrhage

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    Ashish Sharma

    2013-01-01

    Full Text Available Background: Neodymium: YAG (Nd: YAG laser and argon laser has been used to treat premacular hemorrhage either alone or rarely in combination. Materials and Methods: We describe a new technique of treating premacular hemorrhage by performing hyaloidotomy using a combination of argon green-Nd: YAG laser. We utilized subthreshold energy levels of Nd: YAG laser of 2.0 mJ as compared to the normal recommendation of 3.6-50 mJ. Results and Conclusions: This technique is easy, effective, and safe to manage premacular hemorrhage. The principle behind this combined laser treatment was to make the internal limiting membrane (ILM taut by initial exposure to argon green laser, which allowed us to employ the subthreshold energy levels of Nd: YAG laser. We would like to assess the role of this combined treatment modality in comparison to other modalities, including solitary laser therapy in the management of premacular hemorrhage by performing a prospective, randomized long-term study.

  2. Six-month postoperative outcomes of intraoperative OCT-guided surgical cystotomy for refractory cystoid macular edema in diabetic eyes

    Directory of Open Access Journals (Sweden)

    Asahina Y

    2017-11-01

    Full Text Available Yuichi Asahina, Naoko Tachi, Yumi Asahina, Kayoko Yoshimura, Yoshiki Ueta, Yoshihiro Hashimoto Eye Center, Shinseikai Toyama Hospital, Imizu, Toyama, Japan Purpose: This study evaluated the outcomes of surgical cystotomy for recurrent diabetic cystoid macular edema (CME.Patients and methods: We analyzed 20 eyes with a clinical diagnosis of diabetic retinopathy and refractory CME. Release of vitreoretinal adhesion, epiretinal membrane (ERM and internal limiting membrane (ILM peeling and cystotomy guided by intraoperative optical coherence tomography (iOCT were performed in every patient. Pars plana vitrectomy was also performed in 17 patients, 11 of whom also underwent lensectomy and intraocular lens implantation. Central retinal thickness (CRT, central minimum macular thickness (CMMT, macular volume (MV and best-corrected visual acuity (BCVA were compared preoperatively and 1 and 6 months post surgery.Results: CRT, CMMT and MV significantly improved 1 and 6 months post surgery in each group (P<0.01. Significant improvements in BCVA were only observed 6 months post surgery (P<0.01. No intra- or postoperative complications were observed in all patients.Conclusion: CRT, CMMT, MV and BCVA significantly improved 6 months following surgical cystectomy. This implies that iOCT-guided cystotomy could be another treatment option for refractory CME in diabetic eyes. Keywords: diabetic retinopathy, cystoid macular edema, intraoperative OCT, cystotomy

  3. S-34: Üst Düzey U-14 Erkek Futbolcuların Lig Performansları ve Psikolojik Duygu Durum İlişkisi

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    Raziye Dut

    2017-03-01

    Full Text Available GİRİŞ: Her spor dalında olduğu gibi futbolda da futbol oynama amacı, bireysel psikolojik farklılıklar futbolcunun lig performansını etkileyebilmektedir. Özellikle adolesan döneminde fiziksel ve psikolojik farklılıklar oldukça yoğun ve labil yaşanmaktadır. Bu değişikliklerin futbolcunun lig performansına yansıması çoğu zaman kaçınılmaz olabilmektedir. AMAÇ: Aynı kronolojik yaşta milli takım seçilme kampına davet edilmiş erkek futbolcuların lig performansları ve psikolojik duygu durum ilişkilerini incelemektir.GEREÇ-YÖNTEM: 2016-2017 sezonunda U-14 yaş kategorisinde milli takıma seçilme kampına davet edilen 288 sporcudan akademi liglerinde oynayan 158 erkek futbolcu çalışmaya dahil edildi. İlk yarı dönemdeki maç, gol, toplam dakika, sarı/ kırmızı kart sayıları sporda güdülenme ölçeği (SGÖ, kovaks depresyon anketi (KOVAKS, çocuklarda anksiyete tarama ölçeği (ÇATÖ kullanılarak psikolojik duygu durum ilişkisi incelendi. Nicel veriler ortalama ± Standart Sapma (SS ile özetlendi. Gruplar arası farklılıkların saptanmasında chi-square, Mann-Whitney, ANOVA, post hoc Tukey, korelasyon için Spearman testleri kullanıldı. P0,05. SDÖ puanları ile maç (r=-0,136, p=0,045, toplam oynadıkları dakika (r=-0,149, p=0,032, gol sayıları (r=-0,139, p=0,043 arasında düşük negatif korelasyon saptandı. 1. yaş çeyreğinde olanlarda daha fazla patolojik KOVAKS puanı (p=0,003. 1.yaş çeyreğinde SDÖ puanları 2.yaş çeyreğine göre düşüktü (p=0,041.SONUÇ: Spocuların oynadıkları maç sayısının azalmasıyla sporda güdülenmemenin artığı ve attıkları gol sayısıyla özdeşimler düzenlemenin arttiğı saptandı. Psikolojik duygu durum dalgalanmasının sık yaşandığı adolesan döneminde yarışma kaygısı futbol gibi takım oyununda oyuna yansıması kaçınılmaz olabilir. Çalışmanın geniş kitlelerde yapılarak hassas bir dönem olan adolesan d

  4. Phase equilibrium modeling of incipient charnockite formation in NCKFMASHTO and MnNCKFMASHTO systems: A case study from Rajapalaiyam, Madurai Block, southern India

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    Takahiro Endo

    2012-11-01

    Full Text Available Incipient charnockites represent granulite formation on a mesoscopic scale and have received considerable attention in understanding fluid processes in the deep crust. Here we report new petrological data from an incipient charnockite locality at Rajapalaiyam in the Madurai Block, southern India, and discuss the petrogenesis based on mineral phase equilibrium modeling and pseudosection analysis. Rajapalaiyam is a key locality in southern India from where diagnostic mineral assemblages for ultrahigh-temperature (UHT metamorphism have been reported. Proximal to the UHT rocks are patches and lenses of charnockite (Kfs + Qtz + Pl + Bt + Opx + Grt + Ilm occurring within Opx-free Grt-Bt gneiss (Kfs + Pl + Qtz + Bt + Grt + Ilm + Mt which we report in this study. The application of mineral equilibrium modeling on the charnockitic assemblage in NCKFMASHTO system yields a p-T range of ∼820 °C and ∼9 kbar. Modeling of the charnockite assemblage in the MnNCKFMASHTO system indicates a slight shift of the equilibrium condition toward lower p and T (∼760 °C and ∼7.5 kbar, which is consistent with the results obtained from geothermobarometry (710–760 °C, 6.7–7.5 kbar, but significantly lower than the peak temperatures (>1000 °C recorded from the UHT rocks in this locality, suggesting that charnockitization is a post-peak event. The modeling of T versus molar H2O content in the rock (M(H2O demonstrates that the Opx-bearing assemblage in charnockite and Opx-free assemblage in Grt-Bt gneiss are both stable at M(H2O = 0.3 mol%–0.6 mol%, and there is no significant difference in water activity between the two domains. Our finding is in contrast to the previous petrogenetic model of incipient charnockite formation which envisages lowering of water activity and stabilization of orthopyroxene through breakdown of biotite by dehydration caused by the infiltration of CO2-rich fluid. T-XFe3+ (=Fe2O3/(FeO + Fe2O3 in

  5. Long-term changes of macular retinal thickness after idiopathic macular hole surgery

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    Yan Yang

    2014-12-01

    Full Text Available AIM:To determine the changes of regional macular retinal thickness(RTwith spectral domain optical coherence tomography(SD-OCTafter successful pars plana vitrectomy(PPVsurgery with inner limiting membrane(ILMpeeling in patients with idiopathic macular hole.METHODS:A non-randomized retrospective case study on 17 patients(17 eyeswho were hospitalized between March 1, 2011 and June 30, 2013. All 17 eyes had been diagnosed with idiopathic macular hole and thereafter underwent 25G-PPV surgeries performed by the same surgeon with ILM peeling and short-term gas tamponade. In the 6mo-plus follow-up after surgery, these eyes were found to have successful closure in the macular hole. The macular RT of the nine areas in the Early Treatment Diabetic Retinopathy Study was measured by SD-OCT. All patients were applied by SD-OCT with linear scan of the macular. At least four examinations on the operated eye were conducted in contrast to the other normal eye: before the surgery, 3~5wk after the surgery(stage A, 2~3mo after the surgery(stage B, and >6mo after the surgery(stage C.RESULTS:In stage A, the macular RT of operated eyes in the areas of C, IS, II, IN, OS, OI, ON(263.00±39.48, 313.92±18.35, 311.00±18.02, 335.67±19.91, 280.83±33.74, 269.92±23.32, 307.00±28.40were significantly thicker than the corresponding areas of the normal fellow eyes(220.51±23.94, 292.08±21.93, 282.50±20.30, 288.33±20.76, 251.25±17.60, 247.75±21.48, 265.17±24.76μm(PP>0.01. In Stage B, the macular RT in the areas of II, IN, OS(335.67±19.20,319.75±19.20, 273.50±16.89μmwere significantly thicker than the corresponding areas of the normal fellow eyes(286.33±20.46, 293.42±17.64, 252.50±16.32μm(PP> 0.01. In Stage C, the macular RT of operated eyes with the areas of IN(321.17±19.71μmwere significantly thicker than the corresponding areas of the normal fellow eyes(296.25±19.57μm(PP>0.01. Moreover, the macular RT of operated eyes in the areas of ON, IT(307.00±28

  6. Chemical Looping Combustion of Solid Fuels in a 10 kWth Unit Combustion de charge solide en boucle chimique dans une unité de 10 kWth

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    Berguerand N.

    2011-02-01

    Full Text Available The present study is based on previous results from batch experiments which were conducted in a 10 kWth chemical looping combustor for solid fuels using ilmenite, an iron titanium oxide, as the oxygen carrier with two solid fuels: a Mexican petroleum coke and a South African bituminous coal. These experiments involved testing at different fuel reactor temperatures, up to 1030°C, and different particle circulation rates between the air and fuel reactors. Previous results enabled modeling of the reactor system. In particular, it was possible to derive a correlation between measured operational data and actual circulation mass flow, as well as a model that describes the carbon capture efficiency as a function of the residence time and the char reactivity. Moreover, the kinetics of char conversion could be modeled and results showed good agreement with experimental values. The purpose of the present study was to complete these results by developing a model to predict the conversion of syngas with ilmenite in the fuel reactor. Here, kinetic data from investigations of ilmenite in TGA and batch fluidized bed reactors were used. Results were compared with the actual conversions during operation in this 10 kWth unit. Cette étude est basée sur des résultats antérieurs obtenus dans une unité de combustion de charges solides en boucle chimique d’une puissance de 10 kWth. Le transporteur d’oxygène utilisé est de l’ilménite, un minerai de fer et de titane, et les charges solides étudiées sont, d’une part, un coke de pétrole mexicain et, d’autre part, un charbon bitumineux sud africain. Les résultats expérimentaux ont été obtenus à des températures allant jusqu’à 1030°C avec différents débits de transporteur d’oxygène entre les réacteurs d’oxydation et de réduction. La modélisation de la combustion en boucle chimique de charges solides a déjà permis d’établir une corrélation entre le débit de circulation de

  7. Terrestrial Magnetism in Ottoman Empire: Documents and Measurements

    Science.gov (United States)

    Ozcep, Ferhat

    2016-04-01

    In the modern sense, geophysics started with geomagnetic works in the 1600s in Ottoman geography. The period between 1600 and 1800 includes the measurement of magnetic declination, inclination and magnetic field strength. Before these years, there is a little information, such as how to use a compass, in the Kitab-i Bahriye (the Book of Navigation) of Piri Reis, who is one of the most important mariners of the Ottoman Empire. However, this may not mean that magnetic declination was generally understood. The first Turkish scientific book relating to terrestrial magnetism is the book of Fuyuzat-i Miknatissiye that was translated by Ibrahim Müteferrika and printed in 1731. The subject of this book is earth's magnetism. Magnetic compass was mentioned in several books. These areMuhammed al Awfi's "Jami al- Hikayat" (translated into Turkish by Ibn Arabşah); Piri Reis's Kitab-I Bahriye (The Book of "Navigation" or "Seafaring" or "Sea"); Seydi Ali Reis's "Risale-i Mirat-I Kainat min Alat-I Irtifa" (The Treatise called the Mirror of Universe according to the instrument for measuring Altitude) and Kitab Al-"Muhit" Fi˙Ilm'al-Eflak Va'l Abhur (Book of the Regional Seas and the Science of Astronomy and Navigation). There are two original magnetic declination determinations in Istanbul in 1727 and 1893 by Ottoman Turks. Also, many geomagnetic measurements between 1600 and 1917 were carried out during international campaigns in Ottoman geography.This study was carried out in History and Philosophy of Science, University of Cambridge and supported by Istanbul University Reseach Project Unite (project Numbver: IRP-49162).

  8. YAPAY SİNİR AĞLARI KULLANILARAK BAĞ BUDAMA ARTIKLARINDAN ÜRETİLEN YONGA LEVHALARIN ÖZELLİKLERİNİN TAHMİN EDİLMESİ

    Directory of Open Access Journals (Sweden)

    Hüseyin GÜRÜLER

    2015-04-01

    Full Text Available Bu çalışmada, yonga levha hammaddesi olarak beş farklı oranda, bağ budama yongaları ve odun yongaları kullanılmıştır. Öncelikle küçük boyutlu numune paneller üç katmanlı olarak (56x56x2 cm üretilmiştir. Bu levhaların; fiziksel (kalınlığına şişme, su alma ve mekaniksel (eğilme direnci, elastikiyet modülü, iç yapışma ve vida tutma özellikleri belirlenmiştir. Direk ölçüm alma metodu en güvenilir metot olmasına rağmen çok karmaşık ve zaman alıcıdır. Üstelik her oran uygulanabilir değildir. Bu nedenle girdi-çıktı haritalamada en güçlü araçlar olan esnek (yazılımsal hesaplama yöntemleri tercih edilmiştir. Bu aşamada, yapay sinir ağları (YSA tahmin amaçlı kullanıldı. Sonuçlar yapay sinir ağları sisteminin zamandan ve maliyetten kazanç sağlayarak yonga levhaların özelliklerinin belirlenmesinde yetkin olduğunu göstermektedir

  9. AL FIKR AL BALAGHI FI AL MA’ĂNI ‘INDA AS SAKĂKI FI KITABIHI MIFTAHUL ULUM DIRĂSAH BALAGHIYYAH

    Directory of Open Access Journals (Sweden)

    Talqis Nurdianto

    2018-02-01

    Full Text Available Miftāhul ‘Ulūm, written by al-Sakākī, especially the third part, was the beginning of a new phase in the development of Arabic rhetoric. Al-Sakākī divided the rhetoric into three fields of study, which are  (1 Ma’ānī, (2 Bayān, (3 Badī’. However, his style is influenced by philosophers, theologians and their verbal lexicon, which are difficult to take, especially for the ordinary recipient. Al-Sakākī described that his book containing several types of literature, namely, ‘ilm ṣarf in complete version and its conclusion, derivation science, and the grammatical study in the completeness of Ma’ānī and Bayān. The meaning of Makna is the study of completeness and conclusion. Therefore, books and prose, and poem require al-‘Arūḍ and al-Qawāfī include Ṣarf, Grammar, Ma’ānī, Bayān, limitation, reasoning, al’Arūḍ, and al-Qawāfī. He argued that the fields of study were influential in delivering knowledge to the student in order to reach the goal of the author towards his book.This research was an analytical descriptive study of al-Sakākī rhetoric that focused on the normative aspect represented by rhetorical rule and aesthetic aspects. Those aspects were shown by the feeling. Al-Sakākī rhetoric thought is a method based on mental division and has conducted in the construction of many factors, which the most important of them are philosophy and logic. Keywords: thought, rhetoric, meanings, sakkaki, study

  10. Development of high sensitivity gamma and beta sensors for in situ diffusion tests in the mudstone in France

    International Nuclear Information System (INIS)

    Lin, Zhenhua

    2017-01-01

    The precise monitoring of radiotracers, for example used for medical imaging, for the storage of ultimate waste, or for certain industrial applications can be a very complex subject. The development of low-noise sensors with long-term stability and high geometric flexibility were engaged by the AXINT company. (Hautefeuille, et al., 2006). My PhD thesis was focused on experiments in the diffusion of radiotracers, typically to monitor the possible leakage of radioactive products from the geological repositories. We focuses on the study of the 22 Na and 36 Cl ion diffusion, which is one of the highest cation and anions diffusion rate in geological medium, as well as actinides, which represent the majority of the radioactive elements of Stored nuclear waste. This thesis is in continuity with the research carried out by ANDRA (National Agency for Radioactive Waste), under contract with the laboratory ILM (Institute Light Matter), of which AXINT is the main subcontractor. The present project describes the research work that foreseen the radiation impact on the environment for the coming years during the deep disposal of nuclear waste. Our work focus on the investigation and quantification of the radionuclide diffusion through the geological clay barriers. A new in situ experiment was considered by Andra for the study of the radionuclide migration. Compared to previous experiments, this new in situ diffusion test required longer distance (hundreds of mm), longer time-scale (over 10 years), and real time in situ monitoring of radionuclides migration. To fulfill these conditions, the work was organized as following: 1: Conception and dimensional design of the Diffusion of Radio Nuclide (DRN) experiments in solving emission of beta and gamma radiations 2: Development of corresponding beta and gamma monitoring systems by means of sensors located in peripheral boreholes. (author) [fr

  11. Integration experiments and performance studies of a COTS parallel archive system

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsing-bung [Los Alamos National Laboratory; Scott, Cody [Los Alamos National Laboratory; Grider, Gary [Los Alamos National Laboratory; Torres, Aaron [Los Alamos National Laboratory; Turley, Milton [Los Alamos National Laboratory; Sanchez, Kathy [Los Alamos National Laboratory; Bremer, John [Los Alamos National Laboratory

    2010-06-16

    Current and future Archive Storage Systems have been asked to (a) scale to very high bandwidths, (b) scale in metadata performance, (c) support policy-based hierarchical storage management capability, (d) scale in supporting changing needs of very large data sets, (e) support standard interface, and (f) utilize commercial-off-the-shelf (COTS) hardware. Parallel file systems have been asked to do the same thing but at one or more orders of magnitude faster in performance. Archive systems continue to move closer to file systems in their design due to the need for speed and bandwidth, especially metadata searching speeds such as more caching and less robust semantics. Currently the number of extreme highly scalable parallel archive solutions is very small especially those that will move a single large striped parallel disk file onto many tapes in parallel. We believe that a hybrid storage approach of using COTS components and innovative software technology can bring new capabilities into a production environment for the HPC community much faster than the approach of creating and maintaining a complete end-to-end unique parallel archive software solution. In this paper, we relay our experience of integrating a global parallel file system and a standard backup/archive product with a very small amount of additional code to provide a scalable, parallel archive. Our solution has a high degree of overlap with current parallel archive products including (a) doing parallel movement to/from tape for a single large parallel file, (b) hierarchical storage management, (c) ILM features, (d) high volume (non-single parallel file) archives for backup/archive/content management, and (e) leveraging all free file movement tools in Linux such as copy, move, Is, tar, etc. We have successfully applied our working COTS Parallel Archive System to the current world's first petafiop/s computing system, LANL's Roadrunner machine, and demonstrated its capability to address

  12. Multi-surface segmentation of OCT images with AMD using sparse high order potentials.

    Science.gov (United States)

    Oliveira, Jorge; Pereira, Sérgio; Gonçalves, Luís; Ferreira, Manuel; Silva, Carlos A

    2017-01-01

    In age-related macular degeneration (AMD), the quantification of drusen is important because it is correlated with the evolution of the disease to an advanced stage. Therefore, we propose an algorithm based on a multi-surface framework for the segmentation of the limiting boundaries of drusen: the inner boundary of the retinal pigment epithelium + drusen complex (IRPEDC) and the Bruch's membrane (BM). Several segmentation methods have been considerably successful in segmenting retinal layers of healthy retinas in optical coherence tomography (OCT) images. These methods are successful because they incorporate prior information and regularization. Nonetheless, these factors tend to hinder the segmentation for diseased retinas. The proposed algorithm takes into account the presence of drusen and geographic atrophy (GA) related to AMD by excluding prior information and regularization just valid for healthy regions. However, even with this algorithm, prior information and regularization still cause the oversmoothing of drusen in some locations. Thus, we propose the integration of local shape prior in the form of a sparse high order potentials (SHOPs) into the algorithm to reduce the oversmoothing of drusen. The proposed algorithm was evaluated in a public database. The mean unsigned errors, relative to the average of two experts, for the inner limiting membrane (ILM), IRPEDC and BM were 2.94±2.69, 5.53±5.66 and 4.00±4.00 µ m, respectively. Drusen areas measurements were evaluated, relative to the average of two expert graders, by the mean absolute area difference and overlap ratio, which were 1579.7 ± 2106.8 µ m 2 and 0.78 ± 0.11, respectively.

  13. Retinal Thickening and Photoreceptor Loss in HIV Eyes without Retinitis.

    Directory of Open Access Journals (Sweden)

    Cheryl A Arcinue

    Full Text Available To determine the presence of structural changes in HIV retinae (i.e., photoreceptor density and retinal thickness in the macula compared with age-matched HIV-negative controls.Cohort of patients with known HIV under CART (combination Antiretroviral Therapy treatment were examined with a flood-illuminated retinal AO camera to assess the cone photoreceptor mosaic and spectral-domain optical coherence tomography (SD-OCT to assess retinal layers and retinal thickness.Twenty-four eyes of 12 patients (n = 6 HIV-positive and 6 HIV-negative were imaged with the adaptive optics camera. In each of the regions of interest studied (nasal, temporal, superior, inferior, the HIV group had significantly less mean cone photoreceptor density compared with age-matched controls (difference range, 4,308-6,872 cones/mm2. A different subset of forty eyes of 20 patients (n = 10 HIV-positive and 10 HIV-negative was included in the retinal thickness measurements and retinal layer segmentation with the SD-OCT. We observed significant thickening in HIV positive eyes in the total retinal thickness at the foveal center, and in each of the three horizontal B-scans (through the macular center, superior, and inferior to the fovea. We also noted that the inner retina (combined thickness from ILM through RNFL to GCL layer was also significantly thickened in all the different locations scanned compared with HIV-negative controls.Our present study shows that the cone photoreceptor density is significantly reduced in HIV retinae compared with age-matched controls. HIV retinae also have increased macular retinal thickness that may be caused by inner retinal edema secondary to retinovascular disease in HIV. The interaction of photoreceptors with the aging RPE, as well as possible low-grade ocular inflammation causing diffuse inner retinal edema, may be the key to the progressive vision changes in HIV-positive patients without overt retinitis.

  14. Integration experiences and performance studies of A COTS parallel archive systems

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Hsing-bung [Los Alamos National Laboratory; Scott, Cody [Los Alamos National Laboratory; Grider, Bary [Los Alamos National Laboratory; Torres, Aaron [Los Alamos National Laboratory; Turley, Milton [Los Alamos National Laboratory; Sanchez, Kathy [Los Alamos National Laboratory; Bremer, John [Los Alamos National Laboratory

    2010-01-01

    Current and future Archive Storage Systems have been asked to (a) scale to very high bandwidths, (b) scale in metadata performance, (c) support policy-based hierarchical storage management capability, (d) scale in supporting changing needs of very large data sets, (e) support standard interface, and (f) utilize commercial-off-the-shelf(COTS) hardware. Parallel file systems have been asked to do the same thing but at one or more orders of magnitude faster in performance. Archive systems continue to move closer to file systems in their design due to the need for speed and bandwidth, especially metadata searching speeds such as more caching and less robust semantics. Currently the number of extreme highly scalable parallel archive solutions is very small especially those that will move a single large striped parallel disk file onto many tapes in parallel. We believe that a hybrid storage approach of using COTS components and innovative software technology can bring new capabilities into a production environment for the HPC community much faster than the approach of creating and maintaining a complete end-to-end unique parallel archive software solution. In this paper, we relay our experience of integrating a global parallel file system and a standard backup/archive product with a very small amount of additional code to provide a scalable, parallel archive. Our solution has a high degree of overlap with current parallel archive products including (a) doing parallel movement to/from tape for a single large parallel file, (b) hierarchical storage management, (c) ILM features, (d) high volume (non-single parallel file) archives for backup/archive/content management, and (e) leveraging all free file movement tools in Linux such as copy, move, ls, tar, etc. We have successfully applied our working COTS Parallel Archive System to the current world's first petaflop/s computing system, LANL's Roadrunner, and demonstrated its capability to address requirements of

  15. A qualitative readiness-requirements assessment model for enterprise big-data infrastructure investment

    Science.gov (United States)

    Olama, Mohammed M.; McNair, Allen W.; Sukumar, Sreenivas R.; Nutaro, James J.

    2014-05-01

    In the last three decades, there has been an exponential growth in the area of information technology providing the information processing needs of data-driven businesses in government, science, and private industry in the form of capturing, staging, integrating, conveying, analyzing, and transferring data that will help knowledge workers and decision makers make sound business decisions. Data integration across enterprise warehouses is one of the most challenging steps in the big data analytics strategy. Several levels of data integration have been identified across enterprise warehouses: data accessibility, common data platform, and consolidated data model. Each level of integration has its own set of complexities that requires a certain amount of time, budget, and resources to implement. Such levels of integration are designed to address the technical challenges inherent in consolidating the disparate data sources. In this paper, we present a methodology based on industry best practices to measure the readiness of an organization and its data sets against the different levels of data integration. We introduce a new Integration Level Model (ILM) tool, which is used for quantifying an organization and data system's readiness to share data at a certain level of data integration. It is based largely on the established and accepted framework provided in the Data Management Association (DAMADMBOK). It comprises several key data management functions and supporting activities, together with several environmental elements that describe and apply to each function. The proposed model scores the maturity of a system's data governance processes and provides a pragmatic methodology for evaluating integration risks. The higher the computed scores, the better managed the source data system and the greater the likelihood that the data system can be brought in at a higher level of integration.

  16. SARNA-Predict: accuracy improvement of RNA secondary structure prediction using permutation-based simulated annealing.

    Science.gov (United States)

    Tsang, Herbert H; Wiese, Kay C

    2010-01-01

    Ribonucleic acid (RNA), a single-stranded linear molecule, is essential to all biological systems. Different regions of the same RNA strand will fold together via base pair interactions to make intricate secondary and tertiary structures that guide crucial homeostatic processes in living organisms. Since the structure of RNA molecules is the key to their function, algorithms for the prediction of RNA structure are of great value. In this article, we demonstrate the usefulness of SARNA-Predict, an RNA secondary structure prediction algorithm based on Simulated Annealing (SA). A performance evaluation of SARNA-Predict in terms of prediction accuracy is made via comparison with eight state-of-the-art RNA prediction algorithms: mfold, Pseudoknot (pknotsRE), NUPACK, pknotsRG-mfe, Sfold, HotKnots, ILM, and STAR. These algorithms are from three different classes: heuristic, dynamic programming, and statistical sampling techniques. An evaluation for the performance of SARNA-Predict in terms of prediction accuracy was verified with native structures. Experiments on 33 individual known structures from eleven RNA classes (tRNA, viral RNA, antigenomic HDV, telomerase RNA, tmRNA, rRNA, RNaseP, 5S rRNA, Group I intron 23S rRNA, Group I intron 16S rRNA, and 16S rRNA) were performed. The results presented in this paper demonstrate that SARNA-Predict can out-perform other state-of-the-art algorithms in terms of prediction accuracy. Furthermore, there is substantial improvement of prediction accuracy by incorporating a more sophisticated thermodynamic model (efn2).

  17. Macular retinal and choroidal thickness in unilateral amblyopia using swept-source optical coherence tomography.

    Science.gov (United States)

    Araki, Syunsuke; Miki, Atsushi; Goto, Katsutoshi; Yamashita, Tsutomu; Takizawa, Go; Haruishi, Kazuko; Ieki, Yoshiaki; Kiryu, Junichi; Yaoeda, Kiyoshi

    2017-09-15

    To investigate macular retinal and choroidal thickness in amblyopic eyes compared to that in fellow and normal eyes using swept-source optical coherence tomography (SS-OCT). This study examined 31 patients with hyperopic anisometropic amblyopia (6.9 ± 3.8 years, mean ± standard deviation), 15 patients with strabismic amblyopia without anisometropia (7.9 ± 4.2 years), and 24 age-matched controls (7.8 ± 3.3 years). Retinal and choroidal thickness was measured by 3D scans using SS-OCT. A 6-mm area around the fovea was automatically analyzed using the Early Treatment Diabetic Retinopathy Study map. The thickness from SS-OCT was corrected for magnification error using individual axial length, spherical refraction, cylinder refraction, and corneal radius. Retinal thickness was divided into the macular retinal nerve fiber layer (mRNFL), ganglion cell layer + inner plexiform layer (GCL+IPL), ganglion cell complex (GCC), and the inner limiting membrane to the retinal pigment epithelium (ILM-RPE) thickness. Retinal and choroidal thickness was compared among amblyopic, fellow, and normal eyes. In both amblyopia groups, there was no significant difference in the mRNFL, GCL+IPL, and GCC thicknesses among the amblyopic, fellow, and control eyes. In the anisometropic amblyopia group, choroidal thickness (subfovea, center 1 mm, nasal and inferior of the inner ring, nasal of the outer ring, and center 6 mm) of amblyopic eyes were significantly greater than that of fellow and normal eyes. In contrast, none of the choroidal thicknesses were significantly different among the investigated eyes in the strabismic amblyopia group. We found no significant difference in inner retinal thickness in patients with unilateral amblyopia. Although there were significant differences in choroidal thickness with hyperopic anisometropic amblyopia, there was no significant difference for the strabismic amblyopia. The discrepancy in choroidal thickness between the two types of amblyopia may be due

  18. Fingerprinting young ignimbrites in Dominica (Lesser Antilles): Constraints from bulk REEs, apatite chemistry, and U-Th zircon chronology

    Science.gov (United States)

    Frey, H. M.; Manon, M. R.; Brehm, S.

    2015-12-01

    Multiple methods of fingerprinting tephra deposits enable distinction of separate magma batches beneath the island of Dominica. Previous studies have invoked a single large batholith but apatite REE chemistry is inconsistent with generation of multiple ignimbrites by fractional crystallization. The crystal-rich, andesite-dacite (58-66 wt% SiO2) ignimbrites comprise the largest explosive eruption in the Caribbean in the last 200 kyr, erupting a magma volume >58 km3 (Carey and Sigurdsson, 1980). Although the ignimbrites appear to emanate from several vents, their broad similarity in bulk chemistry, phase assemblage (pl + opx + cpx + hbl + ilm + mag + zrn + ap), and mineral composition, has led previous workers to suggest that Dominica is underlain by a single large batholith eruptions younging from north to south. However, bulk REE chemistry, solution ICP-MS chemistry of individual apatite grains, and ion microprobe U-Th dating of zircon rims from pumice clasts suggest a more complex plumbing system. More than 150 pumice clasts from northernmost (Morne aux Diables), northern (Wesley, Pointe Ronde, Grand Savanne), central (Layou, Roseau, Rosalie), and southern (Grand Bay, Grand Fonde) ignimbrites were analyzed for bulk chemistry. Geographically controlled differences exist in the concavity of the middle-heavy REE (Dy*). In central Dominica, apatites from the more evolved Layou Ignimbrite are depleted in middle REE compared to the nearby Roseau Ignimbrite, belying a genetic relationship via fractional crystallization. U-Th zircon rim ages in the northernmost and northern deposits were in secular equilibrium (>350 ka), whereas the central and southern ignimbrites yielded several populations of crystallization ages: Layou (99±12 ka), Roseau (139±12 ka; 65±17 ka), and Grand Bay (107±15 ka; 211±61 ka). Collectively, these observations are consistent with partial melting of magma batches prior to eruption rather than fractional crystallization of a single magma chamber.

  19. [Epidemiological analysis of selected congenital limb malformations in Hengyang].

    Science.gov (United States)

    Li, Na-Na; Yuan, Yu-Mei; Liu, Yong; Dai, Li; Deng, Chang-Fei; Nie, Xing-Hui; Zheng, Xiang-Chi; Hu, Yan-Zhen; Liu, Yun-Rong

    2013-07-01

    To describe the epidemiological characteristics of selected congenital limb malformations (CLM) in newborns of Hengyang. During the period of 2008-2010, cluster sampling survey was adopted to investigate the congenital limb malformations of neonates born to women resident in Hengyang, including Nanyue District, Zhuhui District, Changning City and Hengshan County. Each newborn was examined for the screening of CLM after birth. Limb malformations were grouped into the isolated (ILM) and the syndromic (SLM) form, depending on associated malformations of the affected. Prevalence rates, CLM spectrum and clinical manifestations were analyzed. A total of 170 CLM cases were identified among 52,307 newborns during the study period, resulting overall rate of 32.50/10(4). The rates for isolated and syndromic CLM were 28.29 and 4.21 per 10 000 births respectively. The rates for polydactyly, congenital talipes equinovarus, syndactyly and limb reduction defects were 13.00/10(4), 9.56/10(4), 5.16/10(4) and 3.63/10(4), respectively. No significant difference in rates of overall CLM or specified CLM was observed across urban-rural, gender and maternal age groups. Of the cases affected by polydactyly, syndactyly and limb reduction defects, malformation involved upper limbs, lower limbs and the both accounted for 68.14%, 14.16% and 17.70%. Preterm birth, low birth-weight, still birth and neonatal death were observed more frequently in syndromic cases than in isolated patients. The high CLM prevalence rate and fatality rate in Hengyang suggest that effective measures should be taken to prevent malformations and to improve survival of the affected.

  20. MENGKRITISI KONSEP ISLAMISASI ILMU ISMAIL RAJI AL-FARUQI: Telaah Pemikiran Ziauddin Sardar

    Directory of Open Access Journals (Sweden)

    Muhammad Taufik

    2017-12-01

    ilmu. Konsep ilm meniscayakan umat Islam untuk memahami realitas secara utuh. Hal ini telah dilakukan oleh sarjana dan intelektual Muslim klasik, seperti al-Kindi, al-Farabi, al-Ghazali, Ibnu Rusyd dan sarjana klasik lainnya. Akan tetapi, sarjana Muslim kontemporer tampak mengesampingkan peranan epistemologi ini. Sehingga yang terjadi kemudian adalah justru Islam kehilangan jati diri sebagai kekuatan yang punya orientasi epistemologis yang sebenarnya sudah mapan di era klasik. Konsep Islamisasi ilmu populer di tangan al-Faruqi dan juga Naquib al- Attas. Bagi al-Faruqi, Islamisasi ilmu pengetahuan adalah mengislamkan disiplin-disiplin ilmu atau tepatnya menghasilkan buku-buku pegangan (buku dasar di perguruan tinggi, dengan menuangkan kembali disiplin ilmu modern ke dalam wawasan Islam, setelah dilakukan kajian kritis terhadap kedua sistem pengetahuan Islam dan Barat. Selain itu, al-Faruqi juga memberikan langkah-langkah prosedural bagi terlaksanya program Islamisasi ilmu. Penulis menemukan poin penting dari kajian ini bahwa pemikiran Islamisasi ilmu al-Faruqi inilah yang dikritisi oleh Sardar, menurutnya perumusan epistemologi Islam kontemporer tidak dapat dimulai dengan menitikberatkan pada disiplin ilmu yang sudah ada. Sardar mengungkapkan bahwa epistemologi Islam kontemporer dapat dirumuskan dengan dengan mengembangkan paradigma-paradigma di dalam ekspresi-ekspresi eksternal peradaban Muslim yang meliputi sains dan teknologi, politik dan hubungan-hubungan internasional, struktur-struktur sosial dan kegiatan ekonomi, pembangunan desa dan kota. Semua aspek ekspesi eksternal peradaban Muslim tersebut dapat dipelajari dan dikembangan dalam kaitannya dengan kebutuhan-kebutuhan dan realitas kontemporer. Dari sini Sardar sekali lagi menolak Islamisasi ilmu pengetahuan dimulai dari disiplin ilmu yang sudah ada. Hal ini karena disiplin ilmu tersebut tidak sesuai dengan nilai-nilai Islam

  1. Problematika Pendidikan Islam Perspektif Maqâṣid Sharîʻah

    Directory of Open Access Journals (Sweden)

    Rosidin Rosidin

    2016-11-01

    Full Text Available The article seeks to reveal problems faced by Islamic education from the perspective of Maqâṣid al-Sharîʻah, namely ideological (h}ifẓ al-dîn, practical (h}ifẓ al-nafs, academic (h}ifẓ al-‘aql, relationships or networks (h}ifẓ al-nasl, vocational (h}ifẓ al-mâl and quality (h}ifẓ al-‘irḍ aspects. In order to know the details of crucial problems of the Islamic education along with their alternative solutions, this paper suggests that the Islamic education should consider the insider’s and outsider’s perspective which has four types of roles as follow: a complete observer; b observer as participant; c participant as observer; d complete participant. This article proposes three important implications, are: first, the problems of the Islamic education can be categorized and mapped based on Maqâṣid al-Sharîʻah, in order to ease the analysis of such problems. Second, the analysis of the problems should be based on the insiders’ and outsiders’ point of views, so that it would be able to comprehensively detect the problems of Islamic education and show the inclusiveness of the Islamic education. Third, problem solving alternatives should be oriented at the level of theological (faith and religious [îmân], theoretical (philosophical and empirical [‘ilm], practical (learning and teaching [‘amal] and moral (ethics and aesthetics [akhlâq] realms.

  2. The Protective Role of PAC1-Receptor Agonist Maxadilan in BCCAO-Induced Retinal Degeneration.

    Science.gov (United States)

    Vaczy, A; Reglodi, D; Somoskeoy, T; Kovacs, K; Lokos, E; Szabo, E; Tamas, A; Atlasz, T

    2016-10-01

    A number of studies have proven that pituitary adenylate cyclase activating polypeptide (PACAP) is protective in neurodegenerative diseases. Permanent bilateral common carotid artery occlusion (BCCAO) causes severe degeneration in the rat retina. In our previous studies, protective effects were observed with PACAP1-38, PACAP1-27, and VIP but not with their related peptides, glucagon, or secretin in BCCAO. All three PACAP receptors (PAC1, VPAC1, VPAC2) appear in the retina. Molecular and immunohistochemical analysis demonstrated that the retinoprotective effects are most probably mainly mediated by the PAC1 receptor. The aim of the present study was to investigate the retinoprotective effects of a selective PAC1-receptor agonist maxadilan in BCCAO-induced retinopathy. Wistar rats were used in the experiment. After performing BCCAO, the right eye was treated with intravitreal maxadilan (0.1 or 1 μM), while the left eye was injected with vehicle. Sham-operated rats received the same treatment. Two weeks after the operation, retinas were processed for standard morphometric and molecular analysis. Intravitreal injection of 0.1 or 1 μM maxadilan caused significant protection in the thickness of most retinal layers and the number of cells in the GCL compared to the BCCAO-operated eyes. In addition, 1 μM maxadilan application was more effective than 0.1 μM maxadilan treatment in the ONL, INL, IPL, and the entire retina (OLM-ILM). Maxadilan treatment significantly decreased cytokine expression (CINC-1, IL-1α, and L-selectin) in ischemia. In summary, our histological and molecular analysis showed that maxadilan, a selective PAC1 receptor agonist, has a protective role in BCCAO-induced retinal degeneration, further supporting the role of PAC1 receptor conveying the retinoprotective effects of PACAP.

  3. Localization of endogenous amyloid-β to the coeruleo-cortical pathway: consequences of noradrenergic depletion.

    Science.gov (United States)

    Ross, Jennifer A; Reyes, Beverly A S; Thomas, Steven A; Van Bockstaele, Elisabeth J

    2018-01-01

    The locus coeruleus (LC)-norepinephrine (NE) system is an understudied circuit in the context of Alzheimer's disease (AD), and is thought to play an important role in neurodegenerative and neuropsychiatric diseases involving catecholamine neurotransmitters. Understanding the expression and distribution of the amyloid beta (Aβ) peptide, a primary component of AD, under basal conditions and under conditions of NE perturbation within the coeruleo-cortical pathway may be important for understanding its putative role in pathological states. Thus, the goal of this study is to define expression levels and the subcellular distribution of endogenous Aβ with respect to noradrenergic profiles in the rodent LC and medial prefrontal cortex (mPFC) and, further, to determine the functional relevance of NE in modulating endogenous Aβ 42 levels. We report that endogenous Aβ 42 is localized to tyrosine hydroxylase (TH) immunoreactive somatodendritic profiles of the LC and dopamine-β-hydroxylase (DβH) immunoreactive axon terminals of the infralimbic mPFC (ILmPFC). Male and female naïve rats have similar levels of amyloid precursor protein (APP) cleavage products demonstrated by western blot, as well as similar levels of endogenous Aβ 42 as determined by enzyme-linked immunosorbent assay. Two models of NE depletion, DSP-4 lesion and DβH knockout (KO) mice, were used to assess the functional relevance of NE on endogenous Aβ 42 levels. DSP-4 lesioned rats and DβH-KO mice show significantly lower levels of endogenous Aβ 42 . Noradrenergic depletion did not change APP-cleavage products resulting from β-secretase processing. Thus, resultant decreases in endogenous Aβ 42 may be due to decreased neuronal activity of noradrenergic neurons, or, by decreased stimulation of adrenergic receptors which are known to contribute to Aβ 42 production by enhancing γ-secretase processing under normal physiological conditions.

  4. Tore : [luuletused] / Betti Alver ; [Impressioonid] : Viiu Härm

    Index Scriptorium Estoniae

    Alver, Betti, 1906-1989

    2004-01-01

    Sisu: Tore ; Algav päev ; Allikal ; Maru 1 ; Lähen müüjaks ; Noorus ; Tulipunane vihmavari ; Pedja ; Äkki ilm läks sulale ; Läbi lillede ; Suvi ; Sõnarine ; Ja see oli kõik ; Asjad ; Muusale ; Hambad ; "Vaim, kandes kord triumfipärgi..." ; Hääled ; Vilepuhuja ; Tüli ; Helde andja ; Pühapäevalaps ; Froufrou ; Vooruse võlu ; Sügis 1 ; Talv ; Kuuljale ; Meistrile ; Ei vaibu ; Ilus õde ; Kahepaikne ; Kannibal ; Tuhm kalender ; Raudne taevas ; Koguja ; Inimhetk ; Su nägu ; Läkitus ; Kaks saarlast ; Hing ; Kuus kildu ; Räägi tasa minuga ; Lõppude lõpuks ; Kaduv käsi ; Vana teater ; Raudsed närvid ; Linna taga ; Külm puhang lõõtsub ; Rätsep mure ; Mina ise ; Puust palitu ; Kerjus ; Öölaul ; Pilvele ; Põdural põllul ; Üle tuhande tõkke ; Päikeses ; "Ma nägin und: mind jättis jumal maha..." ; Uni ; Kiivas kuu ; Viimne soov ; Raudahjus põlesid puud ; Linnud naersid ; Arbujate aegu 1 ; Arbujate aegu 2 ; Korallid Emajões ; Udus ; Võlg ; Raugad ; Pähklikoor ; Ekstaas ; "Maailma saatust alati..." ; Tige valgus ; "Selle ilma igav kainus..." ; Sidemed ; "Jäägu teistele alandlik jaatus..." ; Mu juurde voogas ; Suurest haardest ; Laulik ; Suur Nimetu ; Ei tea ; "Mulle meenuvad kauged hommikud..." ; Peegel ; Ime 1936 ; Võrdlus ; Ime 1988 ; Suured voogajad ; Elul on väikene hingemaa ; Ebausklik ; Priiskaja ; Tähetund ; Elu on alles uus ; Kuristikulill ; Süda ; Sa hapramast hapram ; Eluhelbed ; Lootus ; Kes oli su kaitsja ; Lehekuu lumi ; Sügis 2

  5. Ibn Khaldūn’s Social Thought on Bedouin and Ḥaḍar

    Directory of Open Access Journals (Sweden)

    Moh. Pribadi

    2014-12-01

    [Melalui kerangka teori sosiologi modern serta metode penafsiran teks secara historis-sosiologis, penelitian ini berusaha untuk menjelaskan pemikiran sosial Ibn Khaldun tentang masyarakat badui dan ḥaḍar. Ide Ibnu Khaldun tentang masyarakat dapat dilihat pada konsepnya mengenai dua masyarakat ini beserta solidaritas sosial mereka, dengan karakteristik masing-masing. Masyarakat nomaden yang identik dengan masyarakat badui memiliki struktur sosial dan spesifisitas dengan kecenderungan pada kebajikan, ramah, dan keseragaman; sementara masyarakat ḥaḍar memiliki struktur dan kekhasan sosial seperti pluralis, pragmatis, dan hedonis. Dalam hal gaya hidup, masyarakat badui tampak lebih dinamis daripada ḥaḍar. Cara hidup masyarakat badui ditandai dengan terus berpindah dari satu tempat ke tempat lain, dan ini membuat komunitas ini cerdas dalam merumuskan visi, misi, program, dan sasaran yang ingin dicapai dalam hidup. Spesifisitas badui tercermin dalam kesiap-siagaan mereka, satu hal yang tidak terlihat dalam komunitas ḥaḍar. Sementara itu, dengan kemakmuranya, orang ḥaḍar sibuk dengan aktivitas perkotaan dan pembangunan masyarakat sipil. Ibn Khaldun telah berusaha untuk memahami manusia dan keberadaannya secara individu ataupun sosial melalui ‘ilm al-‘umrān. Metodologi sosialnya mencerminkan pandangannya secara keseluruhan melalui pengamatan realitas sosial secara komprehensif. Penulis berpendapat bahwa metodologi sosial Ibn Khaldun yang menggabungkan data dan fakta sosial dengan agama bisa menjadi referensi dan contoh pendekatan yang komprehensif. Ide penting Ibnu Khaldun lainnya adalah tentang perkembangan kecerdasan masyarakat yang meliputi tiga tahap: tamyīzī, tajrībī, dan naẓārī.

  6. Fine Structure of Self-reversed Thermo-remanent Magnetization: Effects of Composition Waves Produced by Ordering During Quench and Annealing of Metastable Ferri-ilmenite Solid Solutions

    Science.gov (United States)

    McEnroe, Suzanne; Robinson, Peter; Fabian, Karl; Harrison, Richard; Thomas, Chris; Mukai, Hiroki; Fjellvåg, Helmer; Putnis, Andrew; Svendby, Kathrine

    2013-04-01

    Magnetic experiments on synthetic ferri-ilmenite samples in the bulk composition range Ilm 60-70, quenched and annealed at high temperatures (T), well above any magnetization temperature, throw new light on metastable chemical phenomena leading to fine-structure in the acquisition of thermoremanent magnetization. Growth of Fe-Ti -ordered domains in a disordered host, or growth and shrinking of adjacent Fe-Ti ordered domains against each other in the process of coarsening, lead to Fe-enrichment in some domains relative to others, influencing magnetization temperature. However, additional Fe-enrichment along domain boundaries during these processes produces Fe-enriched waves on the boundaries, where ferrimagnetic material near the wave crests, magnetizes at a higher T than the bulk of the sample. Because the boundaries are antiphase domain boundaries with opposite Fe-Ti ordering, opposite sides must acquire opposite magnetic moments during cooling, at a temperature above that where bulk normal magnetization begins. This is the "magnetic predestination T" or "TPD", because it sets the stage for normal and self-reversed magnetization on opposite sides of the phase domain boundary. The Fe-enrichment waves are not uniform in different parts of a sample; neither are the compositions along the domain walls. This means "TPD" is generally not a single temperature, but a T range, but reflecting only a small volume of the sample. With further cooling in a positive field, slightly less Fe-enriched but more voluminous ferrimagnetic regions begin to magnetize, leading to a positive magnetic peak, "TMAX". Already here, even less Fe-enriched but still more voluminous ferrimagnetic material, influenced by the domain wall, begins to acquire self-reversed magnetization. This dominates in cooling below "TMAX", eventually leading to totally self-reversed magnetization at "TFR". A Curie temperature obviously cannot be measured meaningfully from a cooling curve in this material of varied

  7. S-32: U-14 Yaş Erkek Futbolcuların Teknik-Taktik Değerlendirmesi ve Atletik Performanslarında Relatif Yaşın Etkisi

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    Raziye Dut

    2017-03-01

    Full Text Available GİRİŞ: Aynı kronolojik yaşta doğum tarihi erken olanların sporda yetenek seçimlerinde avantajlı oldukları bilinmektedir Ancak spora özgü motivasyonda, fonksiyonel kapasitede relatif yaş etkisinin olmadığını gösteren çalışmalar da vardır. AMAÇ: Aynı kronolojik yaştaki erkek futbolcularda teknik/taktik ve atletik performans değerlendirmelerinde relatif yaş etkisini incelemektir. GEREÇ-YÖNTEM: U-14 milli takım seçilme kampına davet edilen 286 erkek futbolcunun, teknik; topa yatkınlık, yaratıcılık, hava hakimiyeti, orta kalitesi, rakip eksiltme ve şut kalitesi, taktik ise pozisyon bilgisi, erken karar, doğru karar, sezgi-erken uyarı, oyunun iki yönü atak ve savunma alt boyutları (1-10 puanlandırıldı. Dikey sıçrama, 10m-20m-30m hız, YOYO IRT1, dayanıklılık, çabukluk-çeviklik, çıkış hızı, maksimal hız gibi atletik performans puanları ile karşılaştırıldı. Veriler ortanca ve Inter Quartile Rate (IQR ile özetlendi. Gruplar arası farklılıklarda Mann-Whitney, ANOVA, post hoc Tukey testleri kullanıldı. P0,05 idi. SONUÇ: Seçilmiş U-14 yaş kategorisinde teknik-taktik ve atletik performans değerlendirmelerinde relatif yaş etkisi bulamadık. Futbol gibi yüksek performanslı bir takım sporunda yetenek, performans kadar teknik ve taktik de erken dönemde geliştirilmeli, yönlendirilmelidir.

  8. Ordovician metamorphism in the Sierras Pampeana: New U-Pb SHRIMP ages in Central-East Valle Fertil and the Velasco batholith

    International Nuclear Information System (INIS)

    Rapela, C.W; Pankhurst, R.J; Baldo, E; Casquet, C.; Galindo, C; Fanning, C.M; Saavedra, J

    2001-01-01

    Magmatic activity, during which extensive I- and S-type granitoids were emplaced in the Famatinian belt and synchronous, though sparse, TTG plutons in the Pampean belt, preceded the accretion of the Precordillera terrane (PT) to the proto-Pacific margin of South America. These three types of granitoid were mainly emplaced in Early Ordovician times (470 90 Ma, Pankhurst et al., 2001). However, little is known about the timing and characteristics of regional metamorphism during the Famatinian orogeny. A key transect in this study is at 30 o 30 31 o 40 , where Grenvillian basement units of the PT are separated by the Bermejo valley from high-grade rocks of the Sierra de Valle Fertil. Geochronological studies have been carried out in the Sierra de Pie de Palo (PT), on the western side of the transect, by Ramos et al. (1998) and Casquet et al. (2001). We are now able to characterise metamorphism on the eastern side of the transect, i.e. the Gondwana margin. To this end we are presenting new U-Pb SHRIMP geochronological studies of western Sierra de Valle Fertil (Baldo et al., 2001), and central-eastern Sierra de Valle Fertil and Sierra de Velasco (this paper). The geology of the central and eastern sectors of the Sierra de Valle Fertil is dominated by a metaluminous sequence of hornblende-biotite tonalites/granodiorites, and suites of troctolitic, noritic and hornblende gabbros emplaced in high-grade metapelites, marbles and amphibolites. The locations of the three samples selected for the isotopic study SVF-3131 is a garnet migmatite composed of Grt + Bt + Pl + Qtz, with Zrn, Mnz, Ap as accessories (mineral symbols after Kretz, 1983). SVF-573 is a cordierite-garnet diatexitic migmatite: Crd (Mg 77-79) + Grt (Alm 57-69, Py 27-32) + Bt (TiO 2 = 3.2-4.5%) + Sil + Pl (An33-35) + Kfs + Qtz; accessories are Spl (included in Grt, ZnO 9-11%), Zrn, Mag, Ilm, Mnz. The widespread occurrence of Crd and Spl in the high-grade rocks indicates that anatexis in central-east Valle Fertil

  9. ORTOGONAL ÇERÇEVELİ BETONARME BİNALARDA KOLON KIRILMALARININ İÇ KUVVETLER ÜZERİNDEKİ ETKİLERİ

    Directory of Open Access Journals (Sweden)

    Nilay KAYA

    2006-02-01

    Full Text Available Bu çalışmada, patlama, araç çarpması, yetersiz veya yanlış tasarım gibi özel nedenlerle meydana gelebilecek kolon kırılmalarının ortogonal çerçeveli betonarme binaların iç kuvvetleri üzerindeki etkileri incelenmiştir. Hesaplar SAP2000 yapı analiz programı ile tamamen statik koşullar altında yapılmıştır. Ele alınan tipik bir çerçeveli sistemde, önce dolgu duvarsız durum için çeşitli kolon kırılma senaryoları düşünülerek sistemin iç kuvvetleri belirlenmiş ve bunlar hasarsız durumdakilerle karşılaştırılmıştır. Benzer hesaplar daha sonra yığma dolgu duvarların mevcut olması hali için yapılmıştır. Analiz sonuçları, kolon kırılmalarının etkilerinin bu kolonların üzerinde bulunduğu birbirine dik akslardaki komşu kolon ve kirişler üzerinde yoğunlaştığını göstermiştir. Ayrıca, dolgusuz çerçevelerde, kırılan kolonlara bağlı olan kirişlerin eğilme momenti kapasiteleri aşılırken, yığma dolgu duvarlı çerçevelerde duvarların sistem elemanlarına önemli desteklerinin olduğu ve kiriş kapasitelerinde aşılma olmadığı belirlenmiştir.

  10. Representativeness of different factors affecting the economic impact of mastitis in dairy herds

    Directory of Open Access Journals (Sweden)

    M. A. Lopes

    2017-07-01

    Full Text Available he objective of this study was to identify and quantify the most representative factor affecting the economic impact of mastitis in dairy cattle herds in order to establish those that should receive greater attention from farmers and technicians to reduce the economic impact of this important disease. A simulation study was conducted with the CU$TO MASTITE program, considering 324 different herds and using combinations of the following factors: somatic cell count (250,000; 500,000; 750,000 and 1,000,000 somatic cells/mL milk; production scale (50; 100 and 150 lactating cows; productivity per animal (10; 20 and 30 L/cow/day; average annual incidence of clinical mastitis (1%; 7% and 15%, and involuntary culling rate due to mastitis (2%; 4% and 6%. Preventive measures included expenses with monitoring [culture and antibiogram, bulk tank somatic cell count (BTSCC, and individual somatic cell counts], pre- and post-dipping, vaccination, treatment of dry cows, and maintenance of the milking machine. Only treatments of clinical cases were considered as curative measures. The impact of mastitis was estimated as total losses plus expenses with prevention and treatment of clinical cases. The mean incidence of clinical mastitis (MIM and BTSCC were significant (P<0.05 in five of the seven models analyzed [economic impact per lactating cow (ILC, economic impact per liter of milk (ILM, economic impact of curative treatment per liter of milk (CTM, economic impact of milk disposal/liter of sold milk (IMD, and economic impact of reduction in production per liter of milk (IRM]. However, the standardized coefficient for MIM was higher in three indicators (ILC, IMD and CTM, a fact rendering this factor more representative when compared to BTSCC, which also had five significant indicators. Comparison of the medians of curative treatments and preventive measures per lactating cow revealed an excellent cost/benefit ratio. These findings demonstrate that both

  11. Comparison of outcomes between 20, 23 and 25 gauge vitrectomy for idiopathic macular hole.

    Science.gov (United States)

    Dihowm, Fatma; MacCumber, Mathew

    2015-01-01

    To compare the results of 20, 23, 25 gauge pars plana vitrectomy (PPV) with two different gas tamponades for idiopathic macular hole (MH) in a multi-surgeon vitroretinal practice. In this comparative, retrospective, interventional case series, the medical charts of 142 eyes/130 patients were reviewed. Patients who matched our inclusion criteria: eye with stage 2, 3, or 4 MH that underwent 20, 23, or 25 gauge PPV, internal limiting membrane (ILM) peeling, and fluid-gas exchange from January, 2005 to May, 2012 and had at least 6 months follow-up. The best current corrected visual acuity (VA) and anatomical status of the MH were assessed by optical coherent tomography (OCT) at 6 months, 1 year, and 2 years after vitrectomy. The MH closed successfully after primary vitrectomy in 86.5 % (20 gauge), 96.4 % (23 gauge), and 92 % (25 gauge). Preoperative VA median were 20\\126 (20 gauge), 20\\100 (23 gauge), and 20\\80 (25 gauge). At 6 months and 2 years postoperative VA did not differ significantly between the 3 groups (p = 0.570, and 0.054 respectively). However, at 12 months postoperative VA median 20\\60 (20 gauge), 20\\69 (23 gauge), and 20\\40 (25 gauge) differ significantly (p = 0.005) likely due to cataract changes. The final median postoperative VA (at 2 years) in 25 gauge PPV group was 20/40 which was better than final visual outcomes for 20, and 23 gauge PPV groups (20/50, and 20/55 respectively). The different was not a statistically significant. MH closed successfully in 96 % (C3F8), and 88.1 % (SF6) (p = 0.063). Preoperative median VA was 20/100 in both groups of gas. At 6 months, 1 year, and 2 years postoperative median VAs did not differ significant between the 2 groups (p = 0.076, 0.343, and 0.309 respectively). MH closed successfully in (96.9 %) 12-14 % C3F8, and (95.3 %) 15-16 % C3F8 (p = 0.611). MH closed in (82.1 %) 18-20 % SF6, and (96.4 %) 22-26 % SF6 (p=0.053). Based on the results of this study, 20, 23, and 25 gauge of PPV have similar MH

  12. Yapı Malzemesi Olarak Denizli Civarında Çıkartılan Kayraktaşlarının Özellikleri

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    Saffet Yağız

    2011-03-01

    Full Text Available Denizli ili çevresinde işletilen doğaltaş ocaklarında, farklı yapıtaşları çıkarılmaktadır. Bunlardan en yaygın olanlar, traverten, kireçtaşı ve kayrak taşı (şist ocaklarıdır. Denizli ilinin kuzey doğusunda, Çal, Bekilli ve Baklan üçgeninde, Mendere masifinin bir üyesi olan kayraktaşları bölgenin önemli doğaltaş kaynaklarındandır. Bu çalışmanın amacı, bölgede işletilen kayrak taşlarının yapıtaşı olarak kullanılabilirliklerinin araştırılmasıdır. Amacı gerçekleştirmek için, bölgede bulunan taş ocakları ve sahalarda jeolojik çalışmalar yapılarak, kayaçların özelliklerini temsil eden örnekler alınmıştır. Kayaç örneklerinde, petrografik, mineralojik (XRD, kimyasal (XRF analizler ve jeomekanik deneyler (tek eksenli sıkışma dayanımı, Schmidt sertlik değeri, ağırlıkca su emme, etkili gözeneklilik, doluluk oranı, eğilme dayanımı, sonik hızı, elastisite modülü, doğal ve doygun birim hacim ağırlık yapılarak elde edilen bulgular kayaçların yapıtaşı olabilirlikleri açısından değerlendirilmiştir. Kayaçlarda yapılan deney ve analizler, uluslararası doğal taş standard ve metotlarına uygun olarak gerçekleştirilmiştir. Sonuç olarak, işletilen kayrak taşları özelikleri itibariyle, binaların iç ve dış cephelerinde, açık mekanlarda ve çevre düzenlemelerinde yapıtaşı ve kaplama malzemesi olarak kullanılabilirler.

  13. Partial melting of amphibolites in the Eastern Segment of the Sveconorwegian orogen, southern Sweden.

    Science.gov (United States)

    Brophy, E.; Hansen, E. C.; Möller, C.; Huffman, M.

    2017-12-01

    Mafic migmatites with amphibolitic melanosome and tonalitic leucosome are a common feature in continental collision orogenic zones. However, the anatexis of mafic rocks has received much less attention than anatexis in felsic, intermediate or pelitic compositions. We examined mafic migmatites along a traverse within the Eastern Segment of the 1.14-0.9 Ga Sveconorwegian orogen, between Forsheda and Fegen southern Sweden. This traverse occurs in the center of a >150 km metamorphic transition from sub-greenschist facies in the east to high-pressure granulite and eclogite facies in the west (Möller and Andersson, unpublished metamorphic map). The Eastern Segment is a parautochthonous belt made up of rocks of the Fennoscandian shield that were deformed and metamorphosed during the Sveconorwegian orogeny. Within the traverse amphibolite bodies occur within migmatitic felsic to intermediate orthogneisses. The first appearance of tonalitic leucosome in amphibolite was observed towards the eastern edge of the traverse and continued to occur sporadically westward ranging in abundance (by outcrop area) from 0 to 25 %. The mineral assemblage in amphibolite is hbl + plag ( An30) + qtz + bt ± grt ± ilm ± ttn ± py ± SO2-rich scp. No examples of peritectic pyroxene associated with leucosome were found. The lack of peritectic pyroxene suggests that a water-rich phase was present at the onset of anatexis. The highly variable amount of leucosome further suggests that the amount of melt generated was determined by the amount of water available. Together these suggest that partial was driven by the local influx of a water-rich fluid. In the higher grade portions further west migmatitic amphibolite with tonalitic leucosome occurs in two varieties: one with peritectic pyroxene and relatively small amounts of leucosome, interpreted as forming by water-undersaturated dehydration melting, and another without peritectic pyroxene and with larger amounts of leucosome which is interpreted

  14. Okul Yöneticisi ve Öğretmen Görüşlerine Göre Okul Yöneticiliğinin Meslekleşmesinin Değerlendirilmesi

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    Sait AKBAŞLI

    2012-11-01

    Full Text Available Bu çalışmada okul müdürlerin, müdür yardımcılarının, öğretmenlerin okul yöneticiliği seçimi, yetiştirilmesi (hizmet öncesi ve hizmet içi, özlük haklarıyla ilgili görüşlerini belirlemek amaçlanmıştır. Çalışma sürecinde, yöneticiliğin meslekleşmesiyle ilgili  alanyazın taraması yapılmış ve daha sonra okul yöneticisi ve öğretmenlere 26 maddelik bir ölçek uygulanmıştır. Araştırmanın evrenini, Konya ilindeki merkez ilçelerdeki (Karatay, Meram, Selçuklu  ilköğretim okullarında 2010/2011 eğitim öğretim yılında görev yapmakta olan okul yöneticileri ve öğretmenler oluşturmaktadır. Araştırmanın örneklemi ise, Konya ilindeki ilköğretim okullarında 2010/2011 eğitim öğretim yılında görev yapmakta olan ve tesadüfi (random yöntemle seçilmiş, 418  okul yöneticisi ve öğretmendir. Çalışma tesadüfi şekilde seçilen örneklem grubu üzerinde yürütülmüştür. Bu yolla elde edilen veriler analiz edilmiştir, ayrıca okul yöneticilerinin seçilme, atanma-yetiştirilme ve görev-özlük alt boyutları incelenmiş ve bunlara yönelik önerilerde bulunulmuştur.

  15. Intraoperative optical coherence tomography assisted analysis of pars Plana vitrectomy for retinal detachment in morning glory syndrome: a case report.

    Science.gov (United States)

    Lytvynchuk, Lyubomyr M; Glittenberg, Carl G; Ansari-Shahrezaei, Siamak; Binder, Susanne

    2017-08-01

    The pathogenesis of non-rhegmatogenous retinal detachment (non-RRD) associated with morning glory syndrome (MGS) is not established, as well as best surgical approach to treat RD. Our purpose was to analyse intraoperative optical coherence tomography data (iOCT) in all steps of pars plana vitrectomy (PPV) for non-RRD in MGS, in order to follow pathophysiological aspects of the disease and to understand the tissues behaviour during surgical workflow. Intraoperative spectral domain optical coherent tomography (iSD-OCT) assisted PPV using Rescan 700 (Carl Zeiss Meditech, Jena, Germany) with epiretinal membrane (ERM) and internal retinal membrane (ILM) peeling, and air endotamponade was performed on the only eye of a 21 years old female with non-RRD associated with MGS. BCVA, pre-, intra- and postoperative OCT were performed along with standard ocular examination. iOCT video and snapshots were analysed intra- and postoperatively using post-processing approach using graphic software. The progression of non-RRD resulted in best corrected visual acuity (BCVA) decrease from 0.8 to 0.2. Triamcinolone enhanced iOCT imaging revealed strong vitreous traction and adhesion above the macula and optic disc. Internal limiting membrane was peeled under iOCT control to prevent the peeling of inner layers of the retinal schisis. No retinal break was detected, and only air endotamponade was performed. The retina reattached during first 4 weeks of follow-up with gradual resolution of intraretinal- and subretinal fluid, and remained stable in 12 months. BCVA improved to 0.8. Based on iSD-OCT findings we assume that non-RRD in this case of MGS is caused primarily by the vitreous traction with further possible formation of the retinal breaks. Retinal reattachment reached only with air endotamponade strongly advocates the tractional component of non-RRD and retinal schisis assotiated with MGS. Early PPV for central non-RRD and retinal schisis with the use of iOCT can be performed in more

  16. Osmanlı’da Zaman-Mekân Kavrayışının Değişimi; Edebi Metinler Üzerinden Bir İrdeleme Change In The Ottoman Space-Time Conception; An Inquiry Through Ottoman Literary Texts

    Directory of Open Access Journals (Sweden)

    Işıl UÇMAN ALTINIŞIK

    2012-12-01

    Full Text Available This study entitled “Change in Ottoman Space-Time Conception:An Inquiry Through Ottoman Literary Texts”, proposes a noveldiscussion on the transformation of Ottoman practices from pre-modernto modern times with the use of recently discovered archival and literarytexts which has been neglected so far in the techno-cultural and socioculturalresearches. In that sense, “change in the Ottoman space-timeconception” is one of the pivotal parameters in order to scrutinize thetransformation of everyday life practices in respect to the changingcontextual phenomena of the pre-modern and the modern, and thispaper attempts to go beyond the prevalent approach of consideringindustrial revolution as the pre-requisite of discussing the socialtransformations brought by modernity. One of the main objectives ofthis study is to examine and visualize the technological, social andcultural processes experienced in the daily life practices that arespecific to the Ottoman realm in relation to the space-time conception.Based on this conceptual framework, the first part named “Müneccims,Muvakkits and the Auspicious Moments: Ottoman Space-TimeConception Before 19th Century” intends to expose the „pre-modernOttoman system‟ in relation to temporal space-time conception rootedin cosmology and nature. Accordingly, the second part under the title“New Space-Time Conception and Modernity in Ottoman Realm” aims toscrutinize the Ottoman experience of modernity in tune with the erosionof cosmological units derived from empirical observation.In this sense „cosmology, astrology (ilm-i nücum, astronomy (ilm-iheyet‟, „müneccimbaşılık ve müneccimler (chief astrologer and theastrologers, „müneccimbaşı takvimleri (chief astrologer calendars‟,„zayiçe (horoscope ve eşref saat (auspicious moment‟ and „muvakkitler,muvakkithaneler‟ are phenomena to be studied. As they display theoperations of the Ottoman psycho-social structure, these

  17. Regulation of diet containing omega-3 polyunsaturated fatty acids on retinal neovascularization in mice

    Directory of Open Access Journals (Sweden)

    Qin Li

    2018-01-01

    Full Text Available AIM: To study the regulation mechanism of diet containing omega-3 polyunsaturated fatty acids(ω-3 PUFAson retinal neovascularization in an oxygen-induced retinopathy(OIRmouse model. METHODS: Sixty C57BL /6J mice, seven-day-old, were classified into 3 groups: A the normal control group, B the OIR model group, C the ω-3 PUFAs diet group. Each group has twenty mice and separated fed by their lactating mice. The normal control group was fed in a standard atmosphere environment, B, C groups were first fed in a hyper-oxygen atmosphere of(75±2% oxygen percentage for 5d, then continue fed in a standard atmosphere. The ω-3 PUFAs diet group was fed with dose base on their weight by 7.5mg/kg/d. All mice were sacrificed when they were seventeen-day-old, the relative neovascularization areas(NAwere calculated by fluorescein angiography on flat-mounted retina. The number of endothelial cell nuclei breaking through the inner linmiting membrane(ILMwas counted on hematoxylin and eosin-stained retinal section. The ω-3PUFAs/ω-6PUFAs relative amount and ratio was measured by GC-MS in the retina. A real-time PCR and Western Blot method were used to detect the mRNA, peroxisome proliferator-avtivated receptor–γ(RPAR-γ, vascular endothelial growth factor-A(VEGF-Aand vascular endothelial growth factor receptor 2(VEGFR-2in the retina. RESULTS: There was a significant different in all groups on the relative neovascularization areas and the number of endothelial cell nuclei breaking through the ILM(FNA=20.45, PILM=48.66, Pt=8.64, Pt=8.91, Pt=38.51, Pt=19.86, PF=129.86, F=112.44; all Pt=23.15, 25.42; t=16.43, 11.95; PFω-3/6=10.30, FRPAR-γ=138.24, FVEGF-A=69.12, FVEGFR-2=52.45; PPPPCONCLUSION:The diet rich with ω-3 PUFAs uplifts the ω-3PUFAs/ω-6PUFAs ratio and activates RPAR-γ to lower expression of VEGF-A and VEGFR-2 to inhabit oxygen induced retinal neovascularization.

  18. GÜNEY MARMARA BÖLGESİNDEKİ BÜYÜK VADİLERİN OLASI DEŞİLME ZAMANI

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    Nizamettin KAZANCI

    2015-06-01

    Full Text Available Güney Marmara Bölgesi’nin (Susurluk drenaj havzası-SDH suları ve tortulları büyük ölçüde önce Manyas ve Ulubat göllerinde toplanır, sonra tek kanaldan Marmara Denizi’ne ulaşır.Mevcut akaçlama sistemi ile buradaki gözlem istasyonları SDH’ndaki aşınma hızını ve dolayısıyla buradaki büyük ölçekli vadilerin kazınma sürelerini araştırma olanağı vermektedir. Bu yönde veri elde etmek için, Ulubat Gölü’nün eski tortulları ve bunların kimyasal kapsamları sondajlar yardımıyla çalışılmıştır. Karotlarla kesilen göl tortulları içindeki bor iyonu alttan üste doğru 4 m seviyesinde aniden artmakta olup bu değişme Emet Vadisi’ndeki borat yataklarının aşınmaya başlamasıyla ortaya çıkmıştır. Aşınma-depolanma ilişkileri dikkate alınarak Emet Vadisi’ndeki deşilme hızı 1,4 cm/yıl, bu değerin tüm araziye uygulanmasıyla vadinin toplam kazılma süresi 75 bin yıl olarak hesaplanmaktadır. Jeolojik süreçlerin tekdüze olmadığı dikkate alınarak, bu yaşın mutlak olmayacağı, ancak mevcut taşınma ve depolanma hızlarına göre vadilerin kazılma süresinin 300 bin yıldan daha da geriye gitmeyeceği söylenebilir. Öyle anlaşılıyor ki, hızlı aşınmanın önemli nedenlerinden birisi Marmara Denizi’nin son Buzul Çağında göl halinde oluşudur. Alçak taban düzeyi, kaynak alan ile birikim yeri arasında belirgin yükseklik farkı yaratmış ve erozyonun hızlanmasına yol açmıştır..

  19. Ehl-i Sünnet Açısından Bilgi ve DeğeriKnowledge and its Value in Terms of the Ahl As-Sunnah

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    ismail yücedağ

    2014-06-01

    Full Text Available Kelâm ilmînin amacı, dinî inançları kesin deliller kullanarak ispat etmektir. Bu nedenle kelâmcılar Kur’an’ı ve iki kısma ayırdıkları Sünnet’in ilk kısmında yer alan mütevâtir haberleri esas almışlardır. Kelâm ilminde üç bilgi edinme yolu olduğu kabul edilmiştir. Bunlar, beş duyu, akıl ve haber-i sâdık’tır. Bilgi edinme yollarından ilk ikisini oluşturan beş duyu ve akıl ile elde edilen bilgiler ile Sünnet’in ilk kısmında yer alan mütevâtir haberin değeri konusunda İslâm âlimleri arasında bir ihtilâf söz konusu değildir. Hicretin II. asrından itibaren, sünnetin ikinci kısmını oluşturan haber-i vahid’in değeri ve itikâdî konularda delil teşkil edip etmeyeceği konusunda âlimler tarihsel süreç içinde birbirinden farklı görüşler ortaya koymuşlardır. Böylelikle problem günümüze kadar devam etmiştir. Konu hakkında fikir yürüten âlimler, Kelâmcılar ve Selefiyye olmak üzere iki ana gruba ayrılmışlardır. Bu çalışmanın amacı, haber-i vâhid hakkındaki fikir ayrılıklarının nedenlerini, kelâmcılar tarafından bilgi edinme yollarından biri olarak kabul edilen haber-i sâdıkı dikkate alarak araştırmaktır. Abstract The purpose of the Kalam science is to prove the religious beliefs by using definitive evidences. For this reason, the Kalam scholars are inclined to Koran and the mutawatir reports which are included in the first part of Ahl As-Sunnah divided into two parts. In the Kalam science, it has been accepted that there are three ways of attaining knowledge. These are the five senses, intelligence, and precise reports. It is not the case that Islamic scholars have a disagreement on not only knowledges obtained through the five senses and intelligence but the value of mutawatir reports included in the first part of Ahl As-Sunnah. As of the second century of Hegira, the scholars have put forward different opinions about whether the value of

  20. Universal single grain amphibole thermobarometer for mantle rocks - preliminary calibration.

    Science.gov (United States)

    Ashchepkov, Igor

    2017-04-01

    SCLM and the third group refer to richterites form the depleted manle peridotites. In SCLM beneat the Sytykanskaya they are more frequent and trace through all the mantle layers. In SCLM beneat the Aykhal they mostly are from the lower and in Komsomolskaya from the middle SCLM parts. In Daldyn field rare amdphibles from Dalnaya are Fe- enriched pargasites belonging to the Ilm bearing peridotites in middle SCLM part as well as in SCLM beneath thr Udachnaya. But there are Fe- low amphiboles substitutng the orthopyroxenes. In Zarnitsa the Cr - hornblendes occur in shallow garnet pyroxenites. One deep seated richterite substitute garnet grains. Rare amphiboles were detedted in Mirninsky filed in Internatiolnaya pipe and reffer to the resorbed and deformed granets from the Garnet -Spinel facies and from 4.0 GPa boundary. Amphiboles are frequent in the SCLM from the northern part of Siberian craton. In SCLM beneath the Kharmai the Fe- encriched varietes are from the Moho boundary. Common Cr-pargasite occurs to 3 GPa in Obnazhennay, pipe, Kharamai field In mantle SCLM beneath Obnazhennaya pipe and circum Anabr region friquent Cr- pargasies and horblendes refer to the relatively hot branch of mantle lithosphere and probably corresponds to the Triassic mantle reactivation. Mantle Cr- hornbleneds occurs on most upper part of the mantle column beneath Quaternary mujeritic Bartoy vocanoes in Transbaikal. The pargasites and kaersutites in this locality refer to more heated conditions and could be found to 2.0 GPa. Grant RFBR 16.-05-000860

  1. S-37: Erkek Futbolcularda Branşa Ait Özellikler, Atletik Performans Testleri ve Relatif Yaş Etkisi

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    Mustafa Şahi̇n

    2017-03-01

    Full Text Available GİRİŞ: Popüler bir takım sporu olan futbolda gruplandırma kronolojik yaş esas alınarak yapılmaktadır. Aynı kronolojik yaşta doğum tarihi erken olanların geç olanlardan daha avantajlı olduğunu gösterir çalışmalar vardır. Yetenekli futbolcunun desteklenmesi, elenmemesi için relatif yaşın spora spesifik özelliklere, performans testlerine etkisi bilinmelidir.AMAÇ: Aynı kronolojik yaştaki erkek futbolcularda relatif yaşın futbol spesifik özelliklere, atletik performans testlerine ve birbirleriyle olan ilişkisini incelemektir.Gereç ve YÖNTEMLER: 2015-2016 sezonunda akademi liginde U-14 kategorisinde milli takıma seçilme kampına davet edilmiş 164 futbolcunun atletik performans göstergeleri ile 2016-2017 sezonun ilk yarısında futbol performansları, oynadıkları maç ve dakika sayıları, gol sayıları incelendi ve aralarındaki ilişkiye bakıldı. Gruplar arası farklılıklar Mann-Whitney, Kruskal-Wallis testi, değişkenler arası ilişki spearman korelasyon testi ile incelendi.BULGULAR: Orta saha oyuncuların diğer pozisyonlarda oynayan sporculara göre daha kısa boy ve daha düşük kiloya sahip olduğu görüldü (p0,05. Sporcuların çeviklik göstergesi ile sürat 10, 20 ve 30m arasında istatistiksel anlamlı orta düzey korelasyon (r=0,387, r=0,400, r=0,377, p<0,001 saptandı. Sürat 10, 20 ve 30m ile attıkları gol sayısı arasında istatistiksel anlamlı negatif orta düzey korelasyon (r=-0,320, r=-0,350, r=-0,351, p<0,001 bulundu. Sürat 30m ile toplam maç sayısı arasında düşük negatif korelasyon (r=-0,144, p<0,05 saptandı. SONUÇ: Futbolcuların atletik performansları arttıkça lig performansları da arttığı görüldü.Futbolcuların lig esnasında daha iyi performans sergilemelerini desteklemek için relatif yaşın etkisini göz önünde bulundurarak atletik performanslarının artırılması önem taşımaktadır.

  2. Evidence of oceanic units in the core of the External Rif (Morocco): intramargin hiatus or South-Tethyan remnants?

    Science.gov (United States)

    Benzaggagh, Mohamed; Mokhtari, Abdelkhader; El Maz, Abdelkhader; Rossi, Philippe; Michard, André; Saddiqi, Omar; Chalouan, Ahmed; Rjimati, Ech-Cherki

    2013-04-01

    Our work is based on extensive field campaigns in the central area of the External Rif Belt and on petrological-geochemical study of the magmatic samples. The aim is to disclose the westward extension of the Mesorif suture zone evidenced in the Temsamane zone of eastern Rif (Michard et al., 2007). We first describe Jurassic-Early Cretaceous sections involving basaltic rocks, spread along the 200 km-long, arcuate Prerif-Mesorif boundary zone west of the Temsamane massif. These sections are thoroughly dated by ammonites and calpionelles from the late Oxfordian to late Berriasian (Benzaggagh, 2011). They display varied traces of submarine, basic volcanism such as volcanoclastic complexes within Upper Berriasian marls, and basalt flows, olistoliths and clasts in the upper Oxfordian-lower Berriasian clayey breccias or in the lower Tithonian brecciated calcareous beds. Volcanic activity took place at the margin of a carbonate platform during the Kimmeridgian-early Tithonian interval, then in a pelagic basin from late Tithonian onward. Petrographic and geochemical studies point to E-MORB basaltic magmas (Rossi, in Benzaggah, 2011), thus testifying for strong crustal thinning in this part of the African paleomargin. Strong support to this inference is found in the occurrence of two small tectonic units of gabbros associated with basalt flows, fault-scarp breccias and radiolarites. A preliminary study of the gabbros reveals that, in thin section, many petrographic types display ortho- to heteradcumulate texture. The typical sequence of cristallization is plag-ol-cpx-ilm and the composition ranges from troctolitic olivine gabbro [An 66-60; Fo 73-71 & 68; cpx Wo 46, En 44, Fs 10 with content in Cr2O3 up to 1%]) to ferrogabbro [(An 50-45); Fo 53; cpx Wo 44, En 40, Fs 16]). Plot of these rocks onto an AFM projection fall on the cumulative composition field along the FM joint and TR patterns display systematic Eu positive anomaly characterizing cumulative plagioclase. Some more

  3. Structure and evolution of the lithospheric mantle beneath Siberian craton, thermobarometric study

    Science.gov (United States)

    Ashchepkov, Igor V.; Pokhilenko, Nikolai P.; Vladykin, Nikolai V.; Logvinova, Alla M.; Afanasiev, Valentin P.; Pokhilenko, Lyudmila N.; Kuligin, Sergei S.; Malygina, Elena V.; Alymova, Natalia A.; Kostrovitsky, Sergey I.; Rotman, Anatolii Y.; Mityukhin, Sergey I.; Karpenko, Mikhail A.; Stegnitsky, Yuri B.; Khemelnikova, Olga S.

    2010-04-01

    70 kbar. Sub-continental lithospheric mantle (SCLM) beneath the Alakite field has been subjected to pervasive multistage metasomatism, as indicated by Fe-enriched Cr-diopsides and Ti-rich low-Ca garnets. Ilmenite PT trends were formed by rising protokimberlites that underwent AFC. In the Upper Muna field the mantle is similar in structure to that of the Alakite region. Fe-rich clinopyroxene-bearing rocks (60-55 kbar) are located between the ilmenite-forming systems (70-60 and 55-40 kbar), sub-Ca garnets start from 40 kbar and become more abundant downward. Beneath the Nakyn field, rhythmic layering is found for peridotites in the lower part ( P > 40 kbar), fertilization by Fe-Cpx (40-50 kbar) follow the Ilm-forming system ˜ 55-60 kbar correlating with the occurrence of depleted (low-Ca) peridotites. Beneath the Anabar fields highly depleted mantle at depth > 40 kbar has been subjected to Fe-metasomatism and pervasive metasomatism that accompanied protokimberlite feeders marked by low Cr-ilmenites accompanied by fertilization. In the upper section abundant garnet- and clinopyroxene-rich peridotites are typical. Comparison of mantle sections reconstructed from monomineral PT estimates from Paleozoic and Mesozoic kimberlites show differences in entrainment levels which were elevated after the Permian-Triassic superplume to > 55-40 kbar without delamination.

  4. ON LOVER AND BELOVED IN NAZAN BEKİROĞLU’S NOVEL LÂ-THE INFINITY SYLLABLENAZAN BEKİROĞLU’NUN LÂ-SONSUZLUK HECESİ ROMANINDA ÂŞIK VE MAŞUK ÜZERİNE

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    Pervin ÇAPAN

    2010-07-01

    önemi roman ve hikâyesinde başarılı eserlere imza atan ve aynı zamanda akademisyen sıfatıyla da ilmî çalışmaları olan Nazan Bekiroğlu’nun Lâ-Sonsuzluk Hecesi adlı romanının da temasını oluşturmaktadır. Bu makalede, söz konusu romanın tematik özelliği ışığında evrensel mânâdaki aşkın, gelenekteki yansımasıyla birleşen doğuş, gelişme ve işlenişi dikkatlere sunulacaktır.

  5. Ash’arī Theologian Miklātī’s Some Theological Views in the Context of Lubāb al-uqūl

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    Asst.Prof.Dr. Vezir Harman

    2016-06-01

    Full Text Available Ebu’l-Ḥajjāj Yusuf b. Muhammad al-Miklâtî is an Ash’arî scholar who lived between the years 550-626 (1155-1229. He has a work entitled Lubāb al-ʿuqūl fī radd ʿalā al-falāsifa fī ʿilm al-uṣūl to defend the opinions of Ahl al-Sunnah by criticizing philosophical views. Miklātī is one of the most important figures who lived in the Muvahhidī state. He is a professor who contributed to learning of Ash’arī kalām system in the North Africa and Andalusia. But today it has not been demonstrated. Therefore, in this article we looked at some theological views of Miklātī in the context of his criticism of the philosophical views.Ebu’l-Ḥajjāj Yûsuf b. Muhammad al-Miklātī is an Ash’arī scholar who lived in North Africa and Andalusia between the years 520-626 (1155-1229. He is one of the tutors working at madrasahs of the Muvahhidī state established by Ibn Tumart. Becoming meeting point of Salafī and philosophical understanding is one of the main factors which makes important the period and the region where he lived. Muvahhidīs on the one hand called for the returning to the Book and the Sunnah, and ordered to burn the works of Malikī fuqahā related to the branches (furūʿ with the reason that they became distant from the Qur’an and the Sunnah. On the other hand, the last great represantatives of Islamic Philosophy, Ibn Tufayl and Averroes wrote their most precious works at Muvahhidî palace.Only extant work of al-Miklâtî is Lubâb al-‘uqûl fî radd ‘alâ al-falâsifa fî ‘ilm al-uṣûl. In Lubâb al-‘uqûl, al-Miklâtî by giving a place to the philosophical opinions about theology, prophethood and the hereafter criticizes the viewpoints of Aristotle, from Periphatetic philosophers al-Fârâbî and Avicenna, from Mu’tazilah Abu Hudhayl al-‘Allaf and Qa’bî. He has benefited from the works of Ash’arî theologians like Baqillanî, al-Juwaynî and al-Ghazzâlî when he make criticism

  6. 27 Mayıs Darbesi Sonrası Celal Bayar ve Eski Demokrat Partililerin Türk Siyasi Hayatına Etkileri Ss, 2585-2598 The Effects of Celal Bayar and Former-Democratic Party Members on Turkish Political Life After the Coup of 27th May

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    Nedim YALANSIZ

    2012-09-01

    Demokrat Parti iktidarına karşı yapıldı. Çok partili hayatın diğer aktörleri olan Cumhuriyet Halk Partisi ve Cumhuriyetçi Köylü Millet Partisi siyasi faaliyetlerine devam ederken, Demokrat Parti bu haktan mahrum edildi. Darbe sonrası içlerinde Başbakan, bakanlar, milletvekilleri, il ve ilçe yöneticileri olmak üzere yaklaşık 500 Demokrat Parti üyesi tutuklandı. Yüksek Adalet Divanı adında bir yüksek mahkeme oluşturuldu. Bu mahkeme bir yıl süren yargılama süreci sonrasında Demokrat Parti üyelerine ölüm cezası ve müebbet hapis de dahil çeşitli cezalar verdi. Ölüm cezasına ve müebbet hapse çarptırılmış eski DP’li Cumhurbaşkanı, bakan, milletvekili ve yönetici, eski Demokrat Parti tabanının zorlaması, memleketin normalleşme ihtiyacı ve aflarından siyasi rant bekleyen yeni ve eski partilerin çabaları sonucu birkaç yıl sonra ağır cezalarından affedildiler. Bazıları da sağlık sorunları nedeniyle daha önce salıverilmişti. Özgürlüklerine kavuştuktan sonra da bu defa kendileri siyasi haklarını, iade-i itibarlarını elde etme mücadelesi verdiler. Ölüm ve hapis cezalarından kurtulmalarına rağmen, siyasi partilere üye olma, milletvekili seçilme hakları ve hatta siyasette yer almadan önce sahip oldukları mesleklerini(örneğin doktorluk gibi yapabilme hakları ellerinden alınmıştı. İktidar ve muhalefet partilerinin anlaşmaları sonucu çıkarılan siyasi aflarla önce mesleklerini yapabilme hakları, sonra siyasi haklarını elde ettiler. Araya 12 Mart ve 12 Eylül darbelerinin girmesiyle bu çok zorlu ve uzun bir süreçte gerçekleşti. Eski DP’liler siyasi haklarını elde etme yanında merkez sağı yeniden Demokrat Parti çatısı altında birleştirmeyi hedeflediler. Kendilerinden koparak kurulan yeni ve güçlü partilerin ve bunların yeni kuşak seçmenlerinin olması nedeniyle bu hedefleri istedikleri şekilde gerçekleşmedi. Bu makalede eski DP’lilerin bu mücadeleleri anlatılmaktadır.

  7. Características quantitativas da carcaça de cordeiros deslanados Morada Nova em função da relação volumoso:concentrado na dieta Quantitative characteristics of the carcass of Morada Nova lambs fed different dietary ratios of forage and concentrate

    Directory of Open Access Journals (Sweden)

    Severino Gonzaga Neto

    2006-08-01

    arteries and jugular veins. Blood was then collected and weigthed. Soon after evisceration, skin, head and extremities of the fore and rear members were removed. The gastrointestinal tract (GIT was emptied, weighted and the value added to that of blood to obtain the empty body weight (EBW, which was calculated by subtracting SBW from GIT + blood weights. The carcasses were weighted and stored at 4°C within a 24-hours period. The empty body (EBW, hot carcass (HCW and cold carcass weights (CCW were all used to calculate the biological (BY, hot carcass (HCY and cold carcass yields (CCY as well as the weight loss by cooling process (CWL. The carcass was divided in five cuts (leg, loin, ribs, shoulder clod and neck that were weighted for calculation of cut yields. The leg was dissected in muscle, bone and fat, and weights of these tissues were expressed in absolute weight and in percentage of leg weight. The muscle:bone and muscle:fat ratios, index of leg muscularity (ILM and the loin eye area (LEA were also calculated. Increasing dietary concentrate from 30 to 60% increased not only hot and cold carcass yields but also biological yield. The increasing levels of concentrate in the diet showed no effect on the percentage of leg muscle. However, it was observed an increase in both fat deposition and rib eye area.

  8. Toplumsal ve Ferdi Düşüncenin Dile Yansımaları (Dil Düşünce İlişkisi The Reflections of Social and Individual Thoughts to Language (Relationship between Language and Thought

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    Nadir İLHAN

    2012-09-01

    örülmektedir. Milleti meydana getiren, millî kimliği ayakta tutan en önemli unsur olan dil sayesinde kişi en özel duygularını ifade edebildiği gibi yine dil sayesinde sosyalleşmekte, toplumun-milletin bir bireyi olmaktadır. Dil düşüncenin evi olduğuna göre insan diliyle düşünmekte, diliyle yaşamaktadır. Toplumsal değerlerin taşıyıcısı olan dile sahip çıkılmadığı zaman değerlere yabancılaşma ortaya çıkacak; değerlere yabancılaşma da millî kimliğe yabancılaşmayı millî kimliği kaybetmeyi beraberinde getirecektir. Kelimelerin kullanımı sırasında onlara yüklenen anlamlara, sanatlı anlatımlara bağlı olarak farklı şekillerde karşımıza çıkan dil,. Günlük işlerimizde kullandığımız konuşma dili ile ilmî çalışmalarda kullanılan terimlerle yüklü bilimsel dil veya kişilerin duygularını, heyecanlarını anlatırken kullandıkları edebî dil şeklinde birbirinden farklı şekillerde nitelendirilebilmektedir. Dil sistemi içerisinde kelimeler, kullanılışı, onlara yüklenen anlamlar ve ifade şekilleri açısından farklılıklar göstermektedir. Dil düşüncenin evi olduğuna göre insan diliyle düşünmekte, diliyle yaşamaktadır. İnsan düşündüğünü ve düşüncelerini ifade edebildiği müddetçe insandır. Toplumsal alandaki herşey dilde de anlatım bulduğu için onu sürekli değişken kılmaktadır. Kısaca “Evrende değişmeyen tek şey herşeyin değiştiğidir” kuralı toplum ve dil ilişkisinde de değişmez bir gerçektir. İsanlık var olduğu sürece geilşim değişim içeisnde olacak bu deiğişimler de dile yansıyacaktır.

  9. Editorial: Focus on X-ray Beams with High Coherence

    Science.gov (United States)

    Robinson, Ian; Gruebel, Gerhard; Mochrie, Simon

    2010-03-01

    Williams, H M Quiney, A G Peele and K A Nugent Imaging of complex density in silver nanocubes by coherent x-ray diffraction R Harder, M Liang, Y Sun, Y Xia and I K Robinson Methodology for studying strain inhomogeneities in polycrystalline thin films during in situ thermal loading using coherent x-ray diffraction N Vaxelaire, H Proudhon, S Labat, C Kirchlechner, J Keckes, V Jacques, S Ravy, S Forest and O Thomas Ptychographic coherent diffractive imaging of weakly scattering specimens Martin Dierolf, Pierre Thibault, Andreas Menzel, Cameron M Kewish, Konstantins Jefimovs, Ilme Schlichting, Konstanze von König, Oliver Bunk and Franz Pfeiffer Dose requirements for resolving a given feature in an object by coherent x-ray diffraction imaging Andreas Schropp and Christian G Schroer FLASH: new opportunities for (time-resolved) coherent imaging of nanostructures R Treusch and J Feldhaus Structure of a single particle from scattering by many particles randomly oriented about an axis: toward structure solution without crystallization? D K Saldin, V L Shneerson, M R Howells, S Marchesini, H N Chapman, M Bogan, D Shapiro, R A Kirian, U Weierstall, K E Schmidt and J C H Spence Analysis of strain and stacking faults in single nanowires using Bragg coherent diffraction imaging V Favre-Nicolin, F Mastropietro, J Eymery, D Camacho, Y M Niquet, B M Borg, M E Messing, L-E Wernersson, R E Algra, E P A M Bakkers, T H Metzger, R Harder and I K Robinson Coherent science at the SwissFEL x-ray laser B D Patterson, R Abela, H-H Braun, U Flechsig, R Ganter, Y Kim, E Kirk, A Oppelt, M Pedrozzi, S Reiche, L Rivkin, Th Schmidt, B Schmitt, V N Strocov, S Tsujino and A F Wrulich Energy recovery linac (ERL) coherent hard x-ray sources Donald H Bilderback, Joel D Brock, Darren S Dale, Kenneth D Finkelstein, Mark A Pfeifer and Sol M Gruner Statistical and coherence properties of radiation from x-ray free-electron lasers E L Saldin, E A Schneidmiller and M V Yurkov Microscopic return point memory in Co

  10. Fenâyî Ehl-i Cennet Efendi, “Teceliyyât” Adlı Arapça Eseri ve Tecelliyyât’a Hasan Rızâyî El-Aksarâyî Tarafından Yapılan Manzûm-Mensûr Türkçe Tercüme/Şerh Üzerine Decent Fellow Fenâyî Ehl-i Cennet, “Teceliyyât” Named Arabic Literary Work And Verse-Article Turkish Translation-On Commentary Was Done By Hasan Rızâyî El-Aksarâyî To “Teceliyyât”

    Directory of Open Access Journals (Sweden)

    Kenan ERDOĞAN

    2013-07-01

    dâyî’den ve Yunus Emre’den ilham alarak kaleme aldığı ilahi formundaki şiirler ağırlıklı olmak üzere oluşturduğu Dîvân’ı, ilmî yönünün ağır bastığı vaazları ve yine Hüdâyî’nin başlattığı “Tecelliyyât” kaleme alma geleneğinin bir tezahürü olarak telakki edilebilecek Tecelliyât’ı ile mutasavvıf şairler içerisinde anılmaya değer şahsiyetlerdendir. Devrinde, Celvetî ekolünün Hüdâyî’den sonra en etkili isimlerinden olan Ehl-i Cennet Efendi’nin devrin en muteber dillerinden Arapça ve Farsça’yı iyi derecede bildiği anlaşılmaktadır. Bazı araştırmacılar tarafından müridlerince yazılıp kendisine atfedildiği de belirtilen Arapça Tecelliyyât’ı; Fenâyî Efendi’nin yaşadığı manevî halleri, rüyaları ve ilhamları konu edinmektedir. Fenâyî’nin yaşadığı bu birtakım rûhî tecrübeleri müridleriyle paylaşmasındaki veya paylaşımın ona atfedilmesindeki amacın; Celvetî sûfîlerini şevk ü iştiyaka ve cezbeye getirip coşturmak, onları yaşadıkları manevî gerilimle Celvetî yoluna ve her şeyden önce İslâm’a bağlamak olduğu düşünülebilir. Bir tarikat pirinin yaşadığı fevkalâdelikleri nazara vermesi, alanın uzmanları tarafından bir tahdis-i ni'met, yani ilâhî nimetlere şükrün bir göstergesi olarak nitelendirilmekte ve tevazudan verilmiş bir taviz olarak görülmemesi gerektiği belirtilmektedir. Üzerinde durulan eser, yine bir Celvetî olan Rızâyî-i Aksarâyî tarafından tercüme edilmiştir.

  11. Macaristan Türkolojisi Üzerine Bir Biyo-Biyografi Denemesi An Attempt At A Bioagrapy of Hungarian Turkology

    Directory of Open Access Journals (Sweden)

    Mehmet GÜMÜŞKILIÇ

    2012-12-01

    üyük hizmetlerde bulundular. Türk-Macar ilişkileri günümüze göre eskiden, belki de daha ileri seviyedeydi. Günümüzde ise bu ilişkiler yeniden canlanmaktadır. Macarlarla Türklerin yakınlığı göz önüne alındığında, bu ilişkileri geliştirmede her iki millete de büyük görevler düşmektedir.Makalemizde; Türklerle ilgili çalışmalar yapan ve Modern Türkolojinin kuruluşundan sonra Türklükle ilgilenen Macar Türkologlarını soyadlarına göre sıraladıktan sonra bunların, ilmî hayat hikâyeleri ile birlikte Türklük bilimiyle ilgili makaleleri -en eski tarihten yeni tarihe kadar- verilmeye çalışılacaktır. Ayrıca bazı Türkologlar hakkında yapılan bir kısım çalışmaların listeleri de makalemizde okuyucuya sunulacaktır. Burada sıralayacağımız Macar Türkologları ve çalışmaları elbette bunlarla sınırlı değildir. Buraya aldığımız ilim adamlarının Türklükle ilgili yazdıkları başka makalelerini, kitapları; sundukları bildirileri; kaleme aldıkları tanıtma yazılarını ve buraya alamadığımız bilim adamlarının da çalışmalarını eklersek bu sayı çok kabaracak ve makale sınırlarını aşacaktır. İleride Macar Türkolojisiyle ilgili ayrıntılı çalışmalar yapılacağı ümidindeyiz. Biz, bir biyo-biyografi denemesi yaparak Macarların Türklere ne kadar önem verdiğini bir nebze de olsa dile getirmeye çalıştık.İleride yapılacak ayrıntılı çalışmalarla Türk-Macar ilişkileri ve dostluğu daha da gelişecektir. Bu konuda katkıda bulunduysak makalemiz hedefine ulaşmış sayılacaktır.

  12. The Mikea Forest Under Threat (southwest Madagascar : How public policy leads to conflicting territories

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    Chantal Blanc-Pamard

    2009-10-01

    é à plusieurs facteurs : pression démographique due à l’immigration, saturation des terres les plus fertiles, assouplissement de la réglementation de l’état sur le défrichement des forêts, et surtout rôle de la culture du maïs associé à l’essor des exportations. La fièvre du maïs entraîne une destruction irréversible de la forêt sèche car le processus de déforestation est suivi d’un processus de savanisation. Le défrichage est une stratégie qui permet de contrôler les ressources et le développement d’un territoire. Ce n’est qu’à la fin des années 1990 que des politiques environnementales ont été mises en œuvre pour réduire le recul de la forêt et préserver la flore et la faune endémiques d’un si grand territoire. La création du parc national Mikea est en cours mais le processus a été ralenti par un projet de mine d’ilménite qui menace une nouvelle fois la forêt. De plus, depuis 2008, une licence de prospection de pétrole dans la région a été accordée. Trois projets contradictoires d’utilisation des terres financés par le gouvernement déstabilisent les populations locales qui ont été encouragées par l’état à préserver la forêt.Con 10 millones de hectáreas, el bosque cubría sólo en 2005 el 16% del territorio de Madagascar. La deforestación está alcanzando proporciones alarmantes y se reconoce como un importante problema ambiental. Este proceso se ha acelerado recientemente, especialmente en el suroeste del país. El principal factor que promueve la deforestación es el cultivo de maíz de tala y quema. La agricultura pionera se está desarrollando rápidamente a costa del bosque. La pérdida de bosque está ligada a varios factores: presión demográfica causada por la inmigración, saturación de las tierras más fértiles, la relajación de las regulaciones estatales en materia de tala de bosques, y sobre todo el papel del cultivo de maíz asociado a un mercado de exportación en auge. La

  13. Programa de Pós-Graduação em Geologia - 2004 - Teses Defendidas - Doutorado - Instituto de Geociências - UFRJ

    Directory of Open Access Journals (Sweden)

    2004-01-01

    tulo: Estudo dos efeitos transientes de temperatura e invasãoem perfis de poços No de páginas: 144 Resumo: Neste trabalho são quantificados os efeitos transientes da tem-peratura e da invasão, causados pelo gradiente radial de temperatura(GRT e/ou pelo gradiente radial de pressão (GRP entre poço e for-mação. Estes efeitos são usados na avaliação das alterações provocadasnos perfis de indução eletromagnética das sondas 2C40, 6FF40, ILM eILD, bem como nos perfis de eletrorresistividade das sondas NormalCurta, LL7, LLS e LLD. Alguns modelos bidimensionais de camadasplano-paralelas, com simetria axial, são adotados nas simulações nu-méricas da condução do calor, do fluxo bifásico de fluidos (imiscíveis eincompressíveis e na obtenção dos perfis de indução eeletrorresistividade. Os fenômenos transientes são simulados com atécnica mista dos métodos de elementos finitos (MEF e diferençasfinitas (MDF, aplicados respectivamente, nas coordenadas espaciais(r, z e temporal (t, das equações diferenciais parciais. A equação deArchie é usada para transformar a saturação em água de formação(nos arenitos em resistividade. O efeito da temperatura é incluído atra-vés da equação de Arps, que altera os valores de resistividades da águada formação, da lama, do filtrado e dos folhelhos. As distribuições es-paço-temporais de resistividades resultantes são usadas para gerar osperfis sintéticos via MEF, em diferentes tempos do intervalo compreen-dido entre 0h e 48h. O presente estudo mostra, além da eficácia dastécnicas numéricas na simulação de fenômenos transientes, que tanto atemperatura quanto a invasão são responsáveis por consideráveis alte-rações nas resistividades aparentes registradas pelas sondas deperfilagem. Estes efeitos transientes podem ser responsáveis por equí-vocos na interpretação de perfis, mas também podem auxiliar na aqui-sição de parâmetros associados aos fenômenos dinâmicos do sistema. 127Anuário do