Contrast-enhanced dual energy mammography with a novel anode/filter combination and artifact reduction: a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Knogler, Thomas; Pinker-Domenig, Katja; Leitner, Sabine; Helbich, Thomas H. [Medical University of Vienna, Department of Biomedical Imaging and Image-Guided Therapy, Vienna (Austria); Medical University of Vienna, Division of Molecular and Gender Imaging, Vienna (Austria); Homolka, Peter; Leithner, Robert [Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Vienna (Austria); Hoernig, Mathias [Siemens AG, Healthcare, X-Ray Products, Erlangen (Germany); Langs, Georg; Waitzbauer, Martin [Medical University of Vienna, Department of Biomedical Imaging and Image-Guided Therapy, Vienna (Austria); Medical University of Vienna, Computational Imaging Research Laboratory, Vienna (Austria)

2016-06-15

To demonstrate the feasibility of contrast-enhanced dual-energy mammography (CEDEM) using titanium (Ti) filtering at 49 kVp for high-energy images and a novel artefact reducing image-subtraction post-processing algorithm. Fifteen patients with suspicious findings (ACR BI-RADS 4 and 5) detected with digital mammography (MG) that required biopsy were included. CEDEM examinations were performed on a modified prototype machine. Acquired HE and low-energy raw data images were registered non-rigidly to compensate for possible subtle tissue motion. Subtracted CEDEM images were generated via weighted subtraction, using a fully automatic, locally adjusted tissue thickness-dependent subtraction factor to avoid over-subtraction at the breast border. Two observers evaluated the MG and CEDEM images according to ACR BI-RADS in two reading sessions. Results were correlated with histopathology. Seven patients with benign and eight with malignant findings were included. All malignant lesions showed a strong contrast enhancement. BI-RADS assessment was altered in 66.6 % through the addition of CEDEM, resulting in increased overall accuracy. With CEDEM, additional lesions were depicted and false-positive rate was reduced compared to MG. CEDEM using Ti filtering with 49 kVp for HE exposures is feasible in a clinical setting. The proposed image-processing algorithm has the potential to reduce artefacts and improve CEDEM images. (orig.)

Adding evidence-based interventions to assertive community treatment : a feasibility study

NARCIS (Netherlands)

Sytema, Sjoerd; Jörg, Frederike; Nieboer, Roeline; Wunderink, Lex

OBJECTIVE: This 24-month study, conducted in The Netherlands, examined the feasibility of enhancing the effectiveness of assertive community treatment (ACT) by adding evidence-based interventions. METHODS: A total of 159 patients were randomly assigned to two ACT teams, one providing standard ACT

Treatment of Alkaline Stripped Effluent in Aerated Constructed Wetlands: Feasibility Evaluation and Performance Enhancement

Directory of Open Access Journals (Sweden)

Keli He

2016-09-01

Full Text Available Ammonium stripping has gained increasing interest for nitrogen recovery in anaerobically digested effluents. However, the stripped effluents often still do not meet discharge standards, having high pH and residual pollutants. Constructed wetlands (CWs are an easy to operate ecosystem and have a long history of application in treatment of wastewaters with extreme pH, such as acid mine drainage. However, knowledge of the mechanistic details involved in the use of CWs to treat high alkaline drainage, such as stripped effluent, is insufficient. This study explored the feasibility and effectiveness of using three sub-surface horizontal flow CWs to treat high alkaline stripped effluent (pH > 10. Two intensification strategies—intermittent aeration and effluent recirculation—were evaluated to enhance nitrogen depuration performance. The results show that the treatment of alkaline stripped effluent is feasible due to the high buffering capacity of the wetlands. Effluent recirculation combined with intermittent artificial aeration improves nitrogen removal, with 71% total nitrogen (TN removal. Ammonia volatilization from the surface of the wetlands in high alkaline conditions only contributed to 3% of the total removed ammonium. The microbial abundance and activity had significant diversity for the various enhancement strategies used in the constructed wetland systems. Anammox is an important process for nitrogen removal in CWs treating alkaline stripped effluent, and possible enhancements of this process should be investigated further.

Usability and feasibility of health IT interventions to enhance Self-Care for Lymphedema Symptom Management in breast cancer survivors

Directory of Open Access Journals (Sweden)

Mei R. Fu, PhD, RN, FAAN

2016-09-01

Conclusions: This usability study provided evidence on breast cancer survivor's acceptance and highly positive evaluation of TOLF's usability as well as feasibility of using technologically-driven delivery model to enhance self-care strategies for lymphedema symptom management.

An Internet-based virtual reality intervention for enhancing self-esteem in women with disabilities: Results of a feasibility study.

Science.gov (United States)

Nosek, Margaret A; Robinson-Whelen, Susan; Hughes, Rosemary B; Nosek, Thomas M

2016-11-01

To examine the feasibility of an online self-esteem enhancement group program for women with disabilities. A sample of 19 racially and ethnically diverse, community-living women with physical disabilities, 22 to 61 years old, participated in a 7-session interactive group intervention (extending Hughes et al., 2004) in the 3-D, immersive, virtual environment of SecondLife.com, using avatars with voice and text communication. Baseline and postintervention questionnaires were administered online. Criteria for determining feasibility were (a) enrollment, (b) engagement, (c) acceptability, and (d) improvement on measures of self-esteem, depression, self-efficacy, and social support. We attained our enrollment goal and engagement exceeded expectations. Acceptability was positive; participants gave "helpful" and "enjoyable" ratings of 3.21 and 3.27, respectively, (mean on a 1 to 4 Likert scale, where 4 = high) to 5 intervention components-session materials, group sharing and discussion, relaxation exercises, action planning, and group excursions. Significant increases from baseline to postintervention were found on the Rosenberg Self-Esteem Scale (p = .02; Cohen's d = .60) and the Center for Epidemiologic Studies Depression Scale-10 (p = .005; Cohen's d = .74), with a trend toward significance on the Generalized Self-Efficacy Scale (p = .08; Cohen's d = .42). The intervention did not significantly affect the measure of social support. An intervention to enhance self-esteem may have a corollary benefit on depressive symptomatology. Offering psycho-educational, small group interventions using online virtual worlds shows promise for circumventing disability-related and environmental barriers to accessing mental health services experienced by women with mobility limitations, and should undergo further development and testing. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Contrast-enhanced power Doppler endosonography and pathological assessment of vascularization in advanced gastric carcinomas--a feasibility study.

Science.gov (United States)

Iordache, Sevastiţa; Filip, Maria-Monalisa; Georgescu, Claudia-Valentina; Angelescu, Cristina; Ciurea, Tudorel; Săftoiu, Adrian

2012-06-01

Besides representing angiogenesis markers, microvascular density (MVD) and vascular endothelial growth factor (VEGF) are two important tools for the assessment of prognosis in patients with gastric cancer. The aim of our study was to assess the Doppler parameters (resistivity and pulsatility indexes) and vascularity index (VI) calculated by contrast-enhanced power Doppler endoscopic ultrasound (CEPD-EUS) in correlation with the expression of intra-tumoral MVD and VEGF in patients with gastric cancer. The study included 20 consecutive patients with advanced gastric carcinoma, but without distant metastasis at initial assessment. All the patients were assessed by contrast-enhanced power Doppler endoscopic ultrasound (EUS) combined with pulsed Doppler examinations in the late venous phase. The vascularity index (VI) was calculated before and after injection of second generation microbubble contrast specific agent (SonoVue 2.4 mL), used as a Doppler signal enhancer. Moreover, pulsed Doppler parameters (resistivity and pulsatility indexes) were further calculated. The correlation between power Doppler parameters and pathological/molecular parameters (MVD assessed through immunohistochemistry with CD31 and CD34, as well as VEGF assessed through real-time PCR) was assessed. Kaplan-Meier survival analysis was used for the assessment of prognosis. Significantly statistical correlations were found between post-contrast VI and CD34 (p=0.0226), VEGF (p=0.0231), VEGF-A (p=0.0464) and VEGF-B (p=0.0022) while pre-contrast VI was correlated only with CD34 expression. Pulsatility index and resistivity index were not correlated with MVD or VEGF expression. Survival analysis demonstrated that VEGF-A is an accurate parameter for survival rate (p=0.045), as compared to VEGF (p=0.085) and VEGF-B (p=0.230). We did not find any correlation between the survival rate and ultrasound parameters (RI, PI, pre-contrast VI or post-contrast VI). Assessment of tumor vascularity using contrast-enhanced

Feasibility of the Enhancing Participation In the Community by improving Wheelchair Skills (EPIC Wheels) program: study protocol for a randomized controlled trial.

Science.gov (United States)

Giesbrecht, Edward M; Miller, William C; Eng, Janice J; Mitchell, Ian M; Woodgate, Roberta L; Goldsmith, Charles H

2013-10-24

Many older adults rely on a manual wheelchair for mobility but typically receive little, if any, training on how to use their wheelchair effectively and independently. Standardized skill training is an effective intervention, but limited access to clinician trainers is a substantive barrier. Enhancing Participation in the Community by Improving Wheelchair Skills (EPIC Wheels) is a 1-month monitored home training program for improving mobility skills in older novice manual wheelchair users, integrating principles from andragogy and social cognitive theory. The purpose of this study is to determine whether feasibility indicators and primary clinical outcome measures of the EPIC Wheels program are sufficiently robust to justify conducting a subsequent multi-site randomized controlled trial. A 2 × 2 factorial randomized controlled trial at two sites will compare improvement in wheelchair mobility skills between an EPIC Wheels treatment group and a computer-game control group, with additional wheelchair use introduced as a second factor. A total of 40 community-dwelling manual wheelchair users at least 55 years old and living in two Canadian metropolitan cities (n = 20 × 2) will be recruited. Feasibility indicators related to study process, resources, management, and treatment issues will be collected during data collection and at the end of the study period, and evaluated against proposed criteria. Clinical outcome measures will be collected at baseline (pre-randomization) and post-intervention. The primary clinical outcome measure is wheelchair skill capacity, as determined by the Wheelchair Skills Test, version 4.1. Secondary clinical outcome measures include wheelchair skill safety, satisfaction with performance, wheelchair confidence, life-space mobility, divided-attention, and health-related quality of life. The EPIC Wheels training program offers several innovative features. The convenient, portable, economical, and adaptable tablet-based, home program model

Quantification of synovitis in the cranio-cervical region: Dynamic contrast enhanced and diffusion weighted magnetic resonance imaging in early rheumatoid arthritis-A feasibility follow up study

Energy Technology Data Exchange (ETDEWEB)

Jeromel, M., E-mail: miran.jeromel@gmail.com [Institute of Radiology, Department for Neuroradiology, University Medical Centre Ljubljana, Zaloska cesta 2, 1000 Ljubljana (Slovenia); Jevtic, V., E-mail: vladimir.jevtic@mf.uni-lj.si [Medical Faculty Ljubljana, Vrazov trg 2, 1104 Ljubljana (Slovenia); Sersa, I., E-mail: igor.sersa@ijs.si [Jozef Stefan Institute, Jamova cesta 39, 1000 Ljubljana (Slovenia); Ambrozic, A., E-mail: ales.ambrozic@mf.uni-lj.si [Department of Rheumatology, University Medical Centre Ljubljana, Vodnikova 62, 1000 Ljubljana (Slovenia); Tomsic, M., E-mail: matija.tomsic@kclj.si [Department of Rheumatology, University Medical Centre Ljubljana, Vodnikova 62, 1000 Ljubljana (Slovenia)

2012-11-15

Objective: To test the feasibility of dynamic contrast enhanced (DCEI) and diffusion weighted (DWI) magnetic resonance imaging (MRI) for quantifying synovitis of the cranio-cervical (C-C) region in patients with early rheumatoid arthritis (RA) and neck pain at the beginning and at a six month follow up. Methods: 27 patients with duration of RA of less than 24 months and neck pain were studied with standard qualitative MRI evaluation and two quantitative MRI methods (DCEI and DWI) at the level of atlantoaxial joints. Rate of early enhancement (REE), enhancement gradient (Genh) and apparent diffusion coefficient (ADC) were extracted from DCEI and DWI data. MRI was coupled with clinical assessment and radiographic imaging. Results: Using standard qualitative MRI evaluation, unequivocal active synovitis (grade 2 or 3 contrast enhancement) was proved in 16 (59%) patients at baseline and 14 (54%) at follow up. DCEI and DWI measurements confirmed active synovitis in 25 (93%) patients at baseline and 24 (92%) at follow up. Average REE, Genh and ADC values decreased during follow up, however the difference was not statistically significant (p > 0.05). Both qualitative and quantitative MRI methods confirmed active inflammatory disease in the C-C region following therapy although all clinical criteria showed signs of improvement of the peripheral disease. Conclusions: The study proved the feasibility of DCEI and DWI MRI for quantifying synovitis of the C-C region in patients with early RA and neck pain. Both techniques can be used as additional method for evaluation of synovitis of the C-C region in RA.

Quantification of synovitis in the cranio-cervical region: Dynamic contrast enhanced and diffusion weighted magnetic resonance imaging in early rheumatoid arthritis—A feasibility follow up study

International Nuclear Information System (INIS)

Jeromel, M.; Jevtič, V.; Serša, I.; Ambrožič, A.; Tomšič, M.

2012-01-01

Objective: To test the feasibility of dynamic contrast enhanced (DCEI) and diffusion weighted (DWI) magnetic resonance imaging (MRI) for quantifying synovitis of the cranio-cervical (C-C) region in patients with early rheumatoid arthritis (RA) and neck pain at the beginning and at a six month follow up. Methods: 27 patients with duration of RA of less than 24 months and neck pain were studied with standard qualitative MRI evaluation and two quantitative MRI methods (DCEI and DWI) at the level of atlantoaxial joints. Rate of early enhancement (REE), enhancement gradient (Genh) and apparent diffusion coefficient (ADC) were extracted from DCEI and DWI data. MRI was coupled with clinical assessment and radiographic imaging. Results: Using standard qualitative MRI evaluation, unequivocal active synovitis (grade 2 or 3 contrast enhancement) was proved in 16 (59%) patients at baseline and 14 (54%) at follow up. DCEI and DWI measurements confirmed active synovitis in 25 (93%) patients at baseline and 24 (92%) at follow up. Average REE, Genh and ADC values decreased during follow up, however the difference was not statistically significant (p > 0.05). Both qualitative and quantitative MRI methods confirmed active inflammatory disease in the C-C region following therapy although all clinical criteria showed signs of improvement of the peripheral disease. Conclusions: The study proved the feasibility of DCEI and DWI MRI for quantifying synovitis of the C-C region in patients with early RA and neck pain. Both techniques can be used as additional method for evaluation of synovitis of the C-C region in RA.

A feasibility study on HTS SMES applications for power quality enhancement through both software simulations and hardware-based experiments

Energy Technology Data Exchange (ETDEWEB)

Kim, A.R.; Kim, J.G.; Kim, S. [Changwon National University, 9 Sarim-Dong, Changwon 641-773 (Korea, Republic of); Park, M., E-mail: paku@changwon.ac.kr [Changwon National University, 9 Sarim-Dong, Changwon 641-773 (Korea, Republic of); Yu, I.K. [Changwon National University, 9 Sarim-Dong, Changwon 641-773 (Korea, Republic of); Seong, K.C. [Superconducting Device and Cryogenics Group, Korea Electrotechnology Research Institute, Changwon 641-120 (Korea, Republic of); Watanabe, K. [HFLSM, Institute for Materials Research, Tohoku University, Sendai 980-8577 (Japan)

2011-11-15

SMES system was simulated to improve the power quality. The utility has one wind power generator and wind speed is continuously changed. Utility frequency was fluctuated due to wind speed variation. We made 10 kJ toroid-type HTS SMES for stabilization of utility frequency. We can monitor the operational characteristics of HTS SMES for power application. Superconducting magnetic energy storage (SMES) which promises the efficiency of more than 95% and fast response becomes a competitive energy storage device. Because of its advantages, SMES can provide benefit as a power quality enhancement device to an utility especially in connection with renewable energy sources. In this paper, a software simulation and an experiment aiming for power quality enhancement are reported. The utility was referred to Ulleung Island in Korea which had one wind power generation system. The simulation was performed using power system computer aided design/electromagnetic transient including DC (PSCAD/EMTDC) and power-hardware-in-the-loop simulation (PHILS) was implemented to monitor the operational characteristics of SMES when it was connected to utility. This study provides a highly reliable simulation results, and the feasibility of a SMES application is discussed.

A feasibility study on HTS SMES applications for power quality enhancement through both software simulations and hardware-based experiments

International Nuclear Information System (INIS)

Kim, A.R.; Kim, J.G.; Kim, S.; Park, M.; Yu, I.K.; Seong, K.C.; Watanabe, K.

2011-01-01

SMES system was simulated to improve the power quality. The utility has one wind power generator and wind speed is continuously changed. Utility frequency was fluctuated due to wind speed variation. We made 10 kJ toroid-type HTS SMES for stabilization of utility frequency. We can monitor the operational characteristics of HTS SMES for power application. Superconducting magnetic energy storage (SMES) which promises the efficiency of more than 95% and fast response becomes a competitive energy storage device. Because of its advantages, SMES can provide benefit as a power quality enhancement device to an utility especially in connection with renewable energy sources. In this paper, a software simulation and an experiment aiming for power quality enhancement are reported. The utility was referred to Ulleung Island in Korea which had one wind power generation system. The simulation was performed using power system computer aided design/electromagnetic transient including DC (PSCAD/EMTDC) and power-hardware-in-the-loop simulation (PHILS) was implemented to monitor the operational characteristics of SMES when it was connected to utility. This study provides a highly reliable simulation results, and the feasibility of a SMES application is discussed.

Quantitative evaluation of the tibial tunnel after anterior cruciate ligament reconstruction using diffusion weighted and dynamic contrast enhanced MRI: a follow-up feasibility study

Energy Technology Data Exchange (ETDEWEB)

Rupreht, Mitja; Seruga, Tomaz; Jevsek, Marko [University Medical Centre Maribor, Radiology Department, Maribor (Slovenia); Jevtic, Vladimir [University of Ljubljana, Medical Faculty, Ljubljana (Slovenia); Sersa, Igor [Jozef Stefan Institute, MRI Laboratory, Ljubljana (Slovenia); Vogrin, Matjaz [University of Medical Centre of Maribor, Department of Orthopaedics, Maribor (Slovenia)

2012-05-15

The aim of the study was to evaluate the feasibility of two quantitative MRI methods: diffusion weighted imaging (DWI) and dynamic contrast enhanced imaging (DCEI), for follow-up assessment of the tibial tunnel after reconstruction of the anterior cruciate ligament (ACL). Twenty-three patients were examined by MRI at 1 and 6 months following ACL reconstruction. DWI and DCEI were utilized for evaluating the region of interest (ROI) within the proximal part of the tibial tunnel. From the resulting apparent diffusion coefficient (ADC) maps, ADC values were calculated. DCEI data were used to extract the enhancement factor (f{sub enh}) and the enhancement gradient (g{sub enh}) for the same ROI. Calculated ADC as well as the f{sub enh} and g{sub enh} had diminished to a statistically significant extent by 6 months after ACL reconstruction. The average ADC value diminished from 1.48 (10{sup -3} mm{sup 2}/s) at 1 month to 1.30 (10{sup -3} mm{sup 2}/s) at 6 months after reconstruction. The average f{sub enh} value decreased from 1.21 at 1 month to 0.50 at 6 months and the average g{sub enh} value decreased from 2.01%/s to 1.15%/s at 6 months, respectively. The study proved feasibility of DWI and DCEI for quantitative assessment of the tibial tunnel at 1 and 6 months after ACL reconstruction. Both methods have the potential for use as an additional tool in the evaluation of new methods of ACL reconstruction. To our knowledge, this is the first time quantitative MRI has been used in the follow-up to the ACL graft healing process. (orig.)

Ventilation imaging of the paranasal sinuses using xenon-enhanced dynamic single-energy CT and dual-energy CT: a feasibility study in a nasal cast

Energy Technology Data Exchange (ETDEWEB)

Thieme, Sven F.; Helck, Andreas D.; Reiser, Maximilian F.; Johnson, Thorsten R.C. [Ludwig Maximilians University Hospital Munich, Institute for Clinical Radiology, Munich (Germany); Moeller, Winfried; Eickelberg, Oliver [Institute for Lung Biology and Disease (iLBD) and Comprehensive Pneumology Center (CPC), Helmholtz Zentrum Muenchen, Neuherberg, Munich (Germany); Becker, Sven [Ludwig-Maximilians-Universitaet, Department of Otorhinolaryngology - Head and Neck Surgery, Munich (Germany); Schuschnig, Uwe [Pari Pharma GmbH, Graefelfing (Germany)

2012-10-15

To show the feasibility of dual-energy CT (DECT) and dynamic CT for ventilation imaging of the paranasal sinuses in a nasal cast. In a first trial, xenon gas was administered to a nasal cast with a laminar flow of 7 L/min. Dynamic CT acquisitions of the nasal cavity and the sinuses were performed. This procedure was repeated with pulsating xenon flow. Local xenon concentrations in the different compartments of the model were determined on the basis of the enhancement levels. In a second trial, DECT measurements were performed both during laminar and pulsating xenon administration and the xenon concentrations were quantified directly. Neither with dynamic CT nor DECT could xenon-related enhancement be detected in the sinuses during laminar airflow. Using pulsating flow, dynamic imaging showed a xenon wash-in and wash-out in the sinuses that followed a mono-exponential function with time constants of a few seconds. Accordingly, DECT revealed xenon enhancement in the sinuses only after pulsating xenon administration. The feasibility of xenon-enhanced DECT for ventilation imaging was proven in a nasal cast. The superiority of pulsating gas flow for the administration of gas or aerosolised drugs to the paranasal sinuses was demonstrated. (orig.)

Feasibility of opportunistic osteoporosis screening in routine contrast-enhanced multi detector computed tomography (MDCT) using texture analysis.

Science.gov (United States)

Mookiah, M R K; Rohrmeier, A; Dieckmeyer, M; Mei, K; Kopp, F K; Noel, P B; Kirschke, J S; Baum, T; Subburaj, K

2018-04-01

This study investigated the feasibility of opportunistic osteoporosis screening in routine contrast-enhanced MDCT exams using texture analysis. The results showed an acceptable reproducibility of texture features, and these features could discriminate healthy/osteoporotic fracture cohort with an accuracy of 83%. This aim of this study is to investigate the feasibility of opportunistic osteoporosis screening in routine contrast-enhanced MDCT exams using texture analysis. We performed texture analysis at the spine in routine MDCT exams and investigated the effect of intravenous contrast medium (IVCM) (n = 7), slice thickness (n = 7), the long-term reproducibility (n = 9), and the ability to differentiate healthy/osteoporotic fracture cohort (n = 9 age and gender matched pairs). Eight texture features were extracted using gray level co-occurrence matrix (GLCM). The independent sample t test was used to rank the features of healthy/fracture cohort and classification was performed using support vector machine (SVM). The results revealed significant correlations between texture parameters derived from MDCT scans with and without IVCM (r up to 0.91) slice thickness of 1 mm versus 2 and 3 mm (r up to 0.96) and scan-rescan (r up to 0.59). The performance of the SVM classifier was evaluated using 10-fold cross-validation and revealed an average classification accuracy of 83%. Opportunistic osteoporosis screening at the spine using specific texture parameters (energy, entropy, and homogeneity) and SVM can be performed in routine contrast-enhanced MDCT exams.

Differentiation between benign and malignant colon tumors using fast dynamic gadolinium-enhanced MR colonography; a feasibility study

International Nuclear Information System (INIS)

Achiam, M.P.; Andersen, L.P.H.; Klein, M.; Logager, V.; Chabanova, E.; Thomsen, H.S.; Rosenberg, J.

2010-01-01

Background: Colorectal cancer will present itself as a bowel obstruction in 16-23% of all cases. However, not all obstructing tumors are malignant and the differentiation between a benign and a malignant tumor can be difficult. The purpose of our study was to determine whether fast dynamic gadolinium-enhanced MR imaging combined with MR colonography could be used to differentiate a benign from a malignant obstructing colon tumor. Methods: Patients with benign colon tumor stenosis, based on diverticulitis, were asked to participate in the study. The same number of patients with verified colorectal cancer was included. Both groups had to be scheduled for surgery to be included. Two blinded observers analyzed the tumors on MR by placing a region of interest in the tumor and a series of parameters were evaluated, e.g. wash-in, wash-out and time-to-peak. Results: 14 patients were included. The wash-in and wash-out rates were significantly different between the benign and malignant tumors, and a clear distinction between benign and malignant disease was therefore possible by looking only at the MR data. Furthermore, MR colography evaluating the rest of the colon past the stenosis was possible with all patients. Conclusion: The results showed the feasibility of using fast dynamic gadolinium-enhanced MR imaging to differentiate between benign and malignant colonic tumors. With a high intra-class correlation and significant differences found on independent segments of the tumor, the method appears to be reproducible. Furthermore, the potential is big in performing a full preoperative colon evaluation even in patients with obstructing cancer. Trial number: (NCT00114829).

Differentiation between benign and malignant colon tumors using fast dynamic gadolinium-enhanced MR colonography; a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Achiam, M.P., E-mail: achiam1@dadlnet.d [Department of Diagnostic Radiology, Copenhagen University Hospital Herlev, Herlev Ringvej, DK-2730 Herlev (Denmark); Department of Surgical Gastroenterology D, Copenhagen University Hospital Herlev, Herlev Ringvej, DK-2730 Herlev (Denmark); Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3C, DK-2200 Copenhagen (Denmark); Andersen, L.P.H.; Klein, M. [Department of Surgical Gastroenterology D, Copenhagen University Hospital Herlev, Herlev Ringvej, DK-2730 Herlev (Denmark); Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3C, DK-2200 Copenhagen (Denmark); Logager, V.; Chabanova, E.; Thomsen, H.S. [Department of Diagnostic Radiology, Copenhagen University Hospital Herlev, Herlev Ringvej, DK-2730 Herlev (Denmark); Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3C, DK-2200 Copenhagen (Denmark); Rosenberg, J. [Department of Surgical Gastroenterology D, Copenhagen University Hospital Herlev, Herlev Ringvej, DK-2730 Herlev (Denmark); Department of Diagnostic Sciences, Faculty of Health Sciences, University of Copenhagen, Blegdamsvej 3C, DK-2200 Copenhagen (Denmark)

2010-06-15

Background: Colorectal cancer will present itself as a bowel obstruction in 16-23% of all cases. However, not all obstructing tumors are malignant and the differentiation between a benign and a malignant tumor can be difficult. The purpose of our study was to determine whether fast dynamic gadolinium-enhanced MR imaging combined with MR colonography could be used to differentiate a benign from a malignant obstructing colon tumor. Methods: Patients with benign colon tumor stenosis, based on diverticulitis, were asked to participate in the study. The same number of patients with verified colorectal cancer was included. Both groups had to be scheduled for surgery to be included. Two blinded observers analyzed the tumors on MR by placing a region of interest in the tumor and a series of parameters were evaluated, e.g. wash-in, wash-out and time-to-peak. Results: 14 patients were included. The wash-in and wash-out rates were significantly different between the benign and malignant tumors, and a clear distinction between benign and malignant disease was therefore possible by looking only at the MR data. Furthermore, MR colography evaluating the rest of the colon past the stenosis was possible with all patients. Conclusion: The results showed the feasibility of using fast dynamic gadolinium-enhanced MR imaging to differentiate between benign and malignant colonic tumors. With a high intra-class correlation and significant differences found on independent segments of the tumor, the method appears to be reproducible. Furthermore, the potential is big in performing a full preoperative colon evaluation even in patients with obstructing cancer. Trial number: (NCT00114829).

WE-DE-207B-04: Quantitative Contrast-Enhanced Spectral Mammography Based On Photon-Counting Detectors: A Feasibility Study

International Nuclear Information System (INIS)

Ding, H; Zhou, B; Beidokhti, D; Molloi, S

2016-01-01

Purpose: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. Methods: Experimental phantom studies were performed on a spectral mammography system based on Si strip photon-counting detectors. Dual-energy images were acquired using 40 kVp and a splitting energy of 34 keV with 3 mm Al pre-filtration. The initial calibration was done with glandular and adipose tissue equivalent phantoms of uniform thicknesses and iodine disk phantoms of various concentrations. A secondary calibration was carried out using the iodine signal obtained from the dual-energy decomposed images and the known background phantom thicknesses and densities. The iodine signal quantification method was validated using phantoms composed of a mixture of glandular and adipose materials, for various breast thicknesses and densities. Finally, the traditional dual-energy weighted subtraction method was also studied as a comparison. The measured iodine signal from both methods was compared to the known iodine concentrations of the disk phantoms to characterize the quantification accuracy. Results: There was good agreement between the iodine mass thicknesses measured using the proposed method and the known values. The root-mean-square (RMS) error was estimated to be 0.2 mg/cm2. The traditional weighted subtraction method also predicted a linear correlation between the measured signal and the known iodine mass thickness. However, the correlation slope and offset values were strongly dependent on the total breast thickness and density. Conclusion: The results of the current study suggest that iodine mass thickness can be accurately quantified with contrast-enhanced spectral mammography. The quantitative information can potentially improve the differentiation between benign and malignant legions. Grant funding from Philips Medical Systems.

WE-DE-207B-04: Quantitative Contrast-Enhanced Spectral Mammography Based On Photon-Counting Detectors: A Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Ding, H; Zhou, B; Beidokhti, D; Molloi, S [University of California, Irvine, CA (United States)

2016-06-15

Purpose: To investigate the feasibility of accurate quantification of iodine mass thickness in contrast-enhanced spectral mammography. Methods: Experimental phantom studies were performed on a spectral mammography system based on Si strip photon-counting detectors. Dual-energy images were acquired using 40 kVp and a splitting energy of 34 keV with 3 mm Al pre-filtration. The initial calibration was done with glandular and adipose tissue equivalent phantoms of uniform thicknesses and iodine disk phantoms of various concentrations. A secondary calibration was carried out using the iodine signal obtained from the dual-energy decomposed images and the known background phantom thicknesses and densities. The iodine signal quantification method was validated using phantoms composed of a mixture of glandular and adipose materials, for various breast thicknesses and densities. Finally, the traditional dual-energy weighted subtraction method was also studied as a comparison. The measured iodine signal from both methods was compared to the known iodine concentrations of the disk phantoms to characterize the quantification accuracy. Results: There was good agreement between the iodine mass thicknesses measured using the proposed method and the known values. The root-mean-square (RMS) error was estimated to be 0.2 mg/cm2. The traditional weighted subtraction method also predicted a linear correlation between the measured signal and the known iodine mass thickness. However, the correlation slope and offset values were strongly dependent on the total breast thickness and density. Conclusion: The results of the current study suggest that iodine mass thickness can be accurately quantified with contrast-enhanced spectral mammography. The quantitative information can potentially improve the differentiation between benign and malignant legions. Grant funding from Philips Medical Systems.

Ready-to-use parenteral amiodarone : A feasibility study towards a long-term stable product formulation

NARCIS (Netherlands)

Jacobs, Maartje S.; Luinstra, Marianne; Moes, Jan Reindert; Chan, Tiffany C. Y.; Minovic, Isidor; Frijlink, Henderik W.; Woerdenbag, Herman J.

Objectives To determine the feasibility of preparing a long-term stable ready-to-use parenteral amiodarone formulation using cyclodextrins as dissolution enhancer. Methods A preformulation study was performed with different molar ratios of hydroxypropyl-beta-cyclodextrin (HP-BCD) or

Sault Tribe Wind Energy Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Toni Osterhout; Global Energy Concepts

2005-07-31

The Sault Tribe conducted a feasibility study on tribal lands in the Upper Peninsula of Michigan to determine the technical and economic feasibility of both small and large-scale wind power development on tribal lands. The study included a wind resource assessment, transmission system analysis, engineering and regulatory analyzes and assessments.

Empirical study on the feasibility of measures for public self-protection capability enhancement; Empirische Untersuchung der Realisierbarkeit von Massnahmen zur Erhoehung der Selbstschutzfaehigkeit der Bevoelkerung

Energy Technology Data Exchange (ETDEWEB)

Goersch, Henning G.; Werner, Ute

2011-07-01

The empirical study on the feasibility of measures for public self-protection capability enhancement covers the following issues with several sections: (1) Introduction: scope of the study; structure of the study. (2) Issue coherence: self-protection; reduction and prevention of damage by personal emergency preparedness, personal emergency preparedness in Germany. (3) Solution coherence: scientific approaches, development of practical problem solution approaches, proposal of a promotion system. (4) Empirical studies: Promotion system evaluation by experts; questioning of the public; Delphi-study on minimum standards in emergency preparedness; local networks in emergency preparedness. (5) Evaluation of models for personal emergency preparedness (M3P). (6) Integration of all research results into the approach of emergency preparedness: scope; recommendations, conclusions.

Feasibility study on commercialized fast reactor cycle systems. (1) Current status of the phase-II study

International Nuclear Information System (INIS)

Sagayama, Yutaka

2005-01-01

A feasibility study on commercialized fast reactors including related nuclear fuel cycle systems has been started from Japanese fiscal year 1999 by a Japanese joint project team of Japan Nuclear Cycle Development Institute and the Japan Atomic Power Company. This project aims at elucidating prominent fast reactor cycle systems that will respond to various needs of society in the future, together with economic competitiveness as future electricity supply systems. Challenging technology goals for the fast reactor cycle systems were defined in five targets: safety, economic competitiveness, reduction of environmental burden, efficient utilization of nuclear fuel resources and enhancement of nuclear non-proliferation. As the results of the feasibility study up to now, it is confirmed as the interim results that the combination of sodium-cooled fast reactors with oxide fuels, advanced aqueous reprocessing and simplified pellet fuel fabrication is highly suited to the development targets. The cost would be highly reduced by the adoption of innovative technologies, which feasibility is relatively clear and some R and D issues are now under progress. (author)

A cask maintenance facility feasibility study

International Nuclear Information System (INIS)

Rennich, M.J.; Medley, L.G.; Attaway, C.R.

1989-01-01

The Oak Ridge National Laboratory (ORNL) is supporting the USDOE Office of Civilian Radioactive Waste Management (OCRWM) in developing a transportation system for spent nuclear fuel (SNF) and defense high level waste (HLW) as a part of the Federal Waste Management System (FWMS). In early 1988, a feasibility study was undertaken to design a stand-alone, green field facility for maintaining the FWMS casks. The feasibility study provided an initial layout facility design, an estimate of the construction cost, and an acquisition schedule for a Cask Maintenance Facility (CMF). The study also helped to define the interfaces between the transportation system and the waste generators, the repository, and a Monitored Retrieveable Storage (MRS) facility. The data, design, and estimated cost resulting from the study have been organized for use in the total transportation system decision-making process. Most importantly, the feasibility study also provides a foundation for continuing design and planning efforts. The feasibility study was based on an assumed stand-alone green field configuration because of the flexibility this design approach provides. A stand-alone facility requires the inclusion with support functions as well as the primary process facilities thus yielding a comprehensive design evaluation and cost estimate. For example, items such as roads, security and waste processing which might be shared with an integrated or collocated facility have been fully costed in the feasibility study. Thus, while the details of the facility design might change, the overall concept used in the study can be applied to other facility configurations as planning for the total FWMS develops

Large scale carbon dioxide production from coal-fired power stations for enhanced oil recovery : a new economic feasibility study

International Nuclear Information System (INIS)

Tontiwachwuthikul, P.; Chan, C.W.; Kritpiphat, W.; DeMontigny, D.; Skoropad, D.; Gelowitz, D.; Aroonwilas, A.; Mourits, F.; Wilson, M.; Ward, L.

1998-01-01

A study was conducted to investigate the economics of capturing carbon dioxide from coal-fired power plants to be subsequently used as a flooding agent for enhanced oil recovery (EOR) technologies. It was shown that the production of CO 2 for EOR projects can be technically and economically feasible, particularly when the concepts of cogeneration and optimization are used to reduce steam and electricity expenditures. This is done by using low-pressure steam and waste heat from various sections of the power generation process. It was shown that recovery costs could range between $0.50 to $2.00 per mscf. This translates to a recovered oil price of in the range of $17.39 to $19.95 per bbl., suggesting that even at today's low oil prices there is room for CO 2 flooding with flue gas extracted CO 2 . Practical implications for Saskatchewan were examined. 15 refs., 4 tabs., 7 figs

100-BC-1 Operable Unit focused feasibility study

International Nuclear Information System (INIS)

Day, R.E.

1994-01-01

The standard Comprehensive Environmental Response, Compensation, and Liability Act feasibility study includes development and screening of alternatives (Phases 1 and 2) and the detailed analysis of alternatives (Phase 3). This focused feasibility study constitutes the Phase 3 portion of the feasibility study process for the remedial alternatives initially developed and screened in the 100 Area Feasibility Study Phases 1 and 2 (DOE-RL 1993a). The focused feasibility study process is conducted in two stages, a Process Document (DOE-RL 1994a) and an operable unit-specific focused feasibility study document, such as this one. The focused feasibility study process is performed by implementing a ''plug-in'' style approach; as defined in greater detail in the Process Document, which is a companion to this document. The objective of this focused feasibility study is to provide decision makers with sufficient information to allow appropriate and timely selection of interim remedial measures for candidate waste sites associated with the 100-BC-1 Operable Unit which is located in the north-central part of the Hanford Site. The interim remedial measure candidate waste sites are determined in the Limited Field Investigation (DOE-RL 1993b). Site profiles are developed for each of these waste sites. The site profiles are used in the application of the plug-in approach. The waste site either plugs into the analysis of the alternatives for the group, or deviations from the developed group alternatives are described and documented

Fusion guidance in endovascular peripheral artery interventions: a feasibility study.

Science.gov (United States)

Sailer, Anna M; de Haan, Michiel W; de Graaf, Rick; van Zwam, Willem H; Schurink, Geert Willem H; Nelemans, Patricia J; Wildberger, Joachim E; Das, Marco

2015-04-01

This study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA). Fusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography. Average time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation). Fluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

Investigation/evaluation of water cooled fast reactor in the feasibility study on commercialized fast reactor cycle systems. Intermediate evaluation of phase-II study

International Nuclear Information System (INIS)

Kotake, Syoji; Nishikawa, Akira

2005-01-01

Feasibility study on commercialized fast reactor cycle systems aims at investigation and evaluation of FBR design requirement's attainability, operation and maintenance, and technical feasibility of the candidate system. Development targets are 1) ensuring safety, 2) economic competitiveness, 3) efficient utilization of resources, 4) reduction of environmental load and 5) enhancement of nuclear non-proliferation. Based on the selection of the promising concepts in the first phase, conceptual design for the plant system has proceeded with the following plant system: a) sodium cooled reactors at large size and medium size module reactors, b) a lead-bismuth cooled medium size reactor, c) a helium gas cooled large size reactor and d) a BWR type large size FBR. Technical development and feasibility has been assessed and the study considers the need of respective key technology development for the confirmation of the feasibility study. (T. Tanaka)

The feasibility study: a health economics perspective

Directory of Open Access Journals (Sweden)

Brenda Gannon

2017-02-01

Full Text Available The remit of research funding bodies is to prioritise funding for research that is of relevance and of high quality. This in turn will aim to raise the quality of healthcare and benefit to patients. Researchers are faced with increasing demands and expectations from the public purse and patients. The emphasis is to improve the quality of their research, with the ultimate aim of improving population health. While guidelines on feasibility study methods concentrate heavily on trials, there appears less guidance on application of health economics within feasibility studies, yet these are a less costly way to determine first of all if a full randomised controlled trial (RCT is feasible. A feasibility study assesses if the study can be done in a small RCT type study. Since by definition, a feasibility study does not evaluate the outcome, researchers often omit the health economics aspects but do however include statistical analysis. This leaves a gap in interpretation for policy makers and potential funders. It also means that any resulting publication does not include relevant information and therefore comparison across studies in terms of difficulty in collecting cost data is not possible. The main aim of this commentary therefore, is to demonstrate a suggested health economics analysis within a feasibility study and to recommend to researchers to include these aspects from the conception of their intervention. This paper proposes a number of points, with rationale for each point, to indicate the health economics data and the potential benefits required for coherent interpretation of the feasibility of future economic evaluations in a full trial. Economic evaluation is necessary if implementation into standard care is anticipated. Therefore, collection and summary analysis of relevant data is good practice at each point of the intervention development. Current guidelines for economic evaluation, for example, The Medical Research Guidelines in the

Renewable Energy Feasibility Study Final Report

Energy Technology Data Exchange (ETDEWEB)

Rooney, Tim [Antares Group Inc.

2013-10-30

The Gila River Indian Community (GRIC or the Community) contracted the ANTARES Group, Inc. (“ANTARES”) to assess the feasibility of solar photovoltaic (PV) installations. A solar energy project could provide a number of benefits to the Community in terms of potential future energy savings, increased employment, environmental benefits from renewable energy generation and usage, and increased energy self-sufficiency. The study addresses a number of facets of a solar project’s overall feasibility, including: Technical appropriateness; Solar resource characteristics and expected system performance; Levelized cost of electricity (LCOE) economic assessment. The Gila River Indian Community (GRIC or the Community) contracted the ANTARES Group, Inc. (“ANTARES”) to prepare a biomass resource assessment study and evaluate the feasibility of a bioenergy project on Community land. A biomass project could provide a number of benefits to the Community in terms of increased employment, environmental benefits from renewable energy generation and usage, and increased energy self-sufficiency. The study addresses a number of facets of a biomass project’s overall feasibility, including: Resource analysis and costs; Identification of potential bioenergy projects; Technical and economic (levelized cost of energy) modeling for selected project configuration.

Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Sailer, Anna M., E-mail: anni.sailer@mumc.nl; Haan, Michiel W. de, E-mail: m.de.haan@mumc.nl; Graaf, Rick de, E-mail: r.de.graaf@mumc.nl; Zwam, Willem H. van, E-mail: w.van.zwam@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands); Schurink, Geert Willem H., E-mail: gwh.schurink@mumc.nl [Maastricht University Medical Center, Department of Surgery (Netherlands); Nelemans, Patricia J., E-mail: patty.nelemans@maastrichtuniversity.nl [Maastricht University Medical Centre, Department of Epidemiology (Netherlands); Wildberger, Joachim E., E-mail: j.wildberger@mumc.nl; Das, Marco, E-mail: m.das@mumc.nl [Maastricht University Medical Center, Department of Radiology (Netherlands)

2015-04-15

PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety.

Fusion Guidance in Endovascular Peripheral Artery Interventions: A Feasibility Study

International Nuclear Information System (INIS)

Sailer, Anna M.; Haan, Michiel W. de; Graaf, Rick de; Zwam, Willem H. van; Schurink, Geert Willem H.; Nelemans, Patricia J.; Wildberger, Joachim E.; Das, Marco

2015-01-01

PurposeThis study was designed to evaluate the feasibility of endovascular guidance by means of live fluoroscopy fusion with magnetic resonance angiography (MRA) and computed tomography angiography (CTA).MethodsFusion guidance was evaluated in 20 endovascular peripheral artery interventions in 17 patients. Fifteen patients had received preinterventional diagnostic MRA and two patients had undergone CTA. Time for fluoroscopy with MRA/CTA coregistration was recorded. Feasibility of fusion guidance was evaluated according to the following criteria: for every procedure the executing interventional radiologists recorded whether 3D road-mapping provided added value (yes vs. no) and whether PTA and/or stenting could be performed relying on the fusion road-map without need for diagnostic contrast-enhanced angiogram series (CEAS) (yes vs. no). Precision of the fusion road-map was evaluated by recording maximum differences between the position of the vasculature on the virtual CTA/MRA images and conventional angiography.ResultsAverage time needed for image coregistration was 5 ± 2 min. Three-dimensional road-map added value was experienced in 15 procedures in 12 patients. In half of the patients (8/17), intervention was performed relying on the fusion road-map only, without diagnostic CEAS. In two patients, MRA roadmap showed a false-positive lesion. Excluding three patients with inordinate movements, mean difference in position of vasculature on angiography and MRA/CTA road-map was 1.86 ± 0.95 mm, implying that approximately 95 % of differences were between 0 and 3.72 mm (2 ± 1.96 standard deviation).ConclusionsFluoroscopy with MRA/CTA fusion guidance for peripheral artery interventions is feasible. By reducing the number of CEAS, this technology may contribute to enhance procedural safety

A cask maintenance facility feasibility study

International Nuclear Information System (INIS)

Rennich, M.J.; Medley, L.G.; Attaway, C.R.

1989-01-01

The Oak Ridge National Laboratory (ORNL) is developing a transportation system for spent nuclear fuel (SNF) and defense high level waste (HLW) as a part of the Federal Waste Management System (FWMS). In early 1988, a feasibility study was undertaken to design a stand-alone, ''green field'' facility for maintaining the FWMS casks. The feasibility study provided an initial layout facility design, an estimate of the construction cost, and an acquisition schedule for a Cask Maintenance Facility (CMF). The study also helped to define the interfaces between the transportation system and the waste generators, the repository, and a Monitored Retrievable Storage (MRS) facility. The data, design, and estimated costs resulting from the study have been organized for use in the total transportation system decision-making process. Most importantly, the feasibility study also provides a foundation for continuing design and planning efforts. Fleet servicing facility studies, operational studies from current cask system operators, a definition of the CMF system requirements, and the experience of others in the radioactive waste transportation field were used as a basis for the feasibility study. In addition, several cask handling facilities were visited to observe and discuss cask operations to establish the functions and methods of cask maintenance expected to be used in the facility. Finally, a peer review meeting was held at Oak Ridge, Tennessee in August, 1988, in which the assumptions, design, layout, and functions of the CMF were significantly refined. Attendees included representatives from industry, the repository and transportation operations

Delayed gadolinium-enhanced MRI of the fibrocartilage disc of the temporomandibular joint--a feasibility study.

Science.gov (United States)

Pittschieler, Elisabeth; Szomolanyi, Pavol; Schmid-Schwap, Martina; Weber, Michael; Egerbacher, Monika; Traxler, Hannes; Trattnig, Siegfried

2014-12-01

To 1) test the feasibility of delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC) at 3 T in the temporomandibular joint (TMJ) and 2) to determine the optimal delay for measurements of the TMJ disc after i.v. contrast agent (CA) administration. MRI of the right and left TMJ of six asymptomatic volunteers was performed at 3 T using a dedicated coil. 2D inversion recovery (2D-IR) sequences were performed at 4 time points covering 120 minutes and 3D gradient-echo (3D GRE) dual flip-angle sequences were performed at 14 time points covering 130 minutes after the administration of 0.2 mmol/kg of Gd-diethylenetriamine pentaacetic acid ion (Gd-DTPA)(2-), i.e., 0.4 mL of Magnevist™ per kg body weight. Pair-wise tests were used to assess differences between pre-and post-contrast T1 values. 2D-IR sequences showed a statistically significant drop (pfibrocartilage disc of the TMJ. The recommended measurement time for dGEMRIC in the TMJ after i.v. CA administration is from 60 to 120 minutes. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

Washoe Tribe Alternative Energy Feasibility Study Final Report

Energy Technology Data Exchange (ETDEWEB)

Johnson, Jennifer [Washoe Tribe of NV and CA

2014-10-01

The Washoe Tribe of Nevada and California was awarded funding to complete the Washoe Tribe Alternative Energy Feasibility Study project. The main goal of the project was to complete an alternative energy feasibility study. This study was completed to evaluate “the potential for development of a variety of renewable energy projects and to conduct an alternative energy feasibility study that determines which alternative energy resources have the greatest economic opportunity for the Tribe, while respecting cultural and environmental values” (Baker-Tilly, 2014). The study concluded that distributed generation solar projects are the best option for renewable energy development and asset ownership for the Washoe Tribe. Concentrating solar projects, utility scale wind projects, geothermal, and biomass resource projects were also evaluated during the study and it was determined that these alternatives would not be feasible at this time.

Do feasibility studies contribute to, or avoid, waste in research?

Science.gov (United States)

Morgan, Ben; Hejdenberg, Jennie; Hinrichs-Krapels, Saba; Armstrong, David

2018-01-01

In the context of avoiding research waste, the conduct of a feasibility study before a clinical trial should reduce the risk that further resources will be committed to a trial that is likely to 'fail'. However, there is little evidence indicating whether feasibility studies add to or reduce waste in research. Feasibility studies funded by the National Institute for Health Research's (NIHR) Research for Patient Benefit (RfPB) programme were examined to determine how many had published their findings, how many had applied for further funding for a full trial and the timeframe in which both of these occurred. A total of 120 feasibility studies which had closed by May 2016 were identified and each Principal Investigator (PI) was sent a questionnaire of which 89 responses were received and deemed suitable for analysis. Based on self reported answers from the PIs a total of 57 feasibility studies were judged as feasible, 20 were judged not feasible and for 12 it was judged as uncertain whether a full trial was feasible. The RfPB programme had spent approximately £19.5m on the 89 feasibility studies of which 16 further studies had been subsequently funded to a total of £16.8m. The 20 feasibility studies which were judged as not feasible potentially saved up to approximately £20m of further research funding which would likely to have not completed successfully. The average RfPB feasibility study took 31 months (range 18 to 48) to complete and cost £219,048 (range £72,031 to £326,830) and the average full trial funded from an RfPB feasibility study took 42 months (range 26 to 55) to complete and cost £1,163,996 (range £321,403 to £2,099,813). The average timeframe of feasibility study and full trial was 72 months (range 56 to 91), however in addition to this time an average of 10 months (range -7 to 29) was taken between the end of the feasibility study and the application for the full trial, and a further average of 18 months (range 13 to 28) between the

Differentiating pheochromocytoma from lipid-poor adrenocortical adenoma by CT texture analysis: feasibility study.

Science.gov (United States)

Zhang, Gu-Mu-Yang; Shi, Bing; Sun, Hao; Jin, Zheng-Yu; Xue, Hua-Dan

2017-09-01

To investigate the feasibility of using CT texture analysis (CTTA) to differentiate pheochromocytoma from lipid-poor adrenocortical adenoma (lp-ACA). Ninety-eight pheochromocytomas and 66 lp-ACAs were included in this retrospective study. CTTA was performed on unenhanced and enhanced images. Receiver operating characteristic (ROC) analysis was performed, and the area under the ROC curve (AUC) was calculated for texture parameters that were significantly different for the objective. Diagnostic accuracies were evaluated using the cutoff values of texture parameters with the highest AUCs. Compared to lp-ACAs, pheochromocytomas had significantly higher mean gray-level intensity (Mean), entropy, and mean of positive pixels (MPP), but lower skewness and kurtosis on unenhanced images (P feasible to use CTTA to differentiate pheochromocytoma from lp-ACA.

Fuel assembly assessment from CVD image analysis: A feasibility study

International Nuclear Information System (INIS)

Lindsay, C.S.; Lindblad, T.

1997-05-01

The Swedish Nuclear Inspectorate commissioned a feasibility study of automatic assessment of fuel assemblies from images obtained with the digital Cerenkov viewing device currently in development. The goal is to assist the IAEA inspectors in evaluating the fuel since they typically have only a few seconds to inspect an assembly. We report results here in two main areas: Investigation of basic image processing and recognition techniques needed to enhance the images and find the assembly in the image; Study of the properties of the distributions of light from the assemblies to determine whether they provide unique signatures for different burn-up and cooling times for real fuel or indicate presence of non-fuel. 8 refs, 27 figs

A study of critical paths for feasibility studies of mining projects

International Nuclear Information System (INIS)

Sayadi, R.

2002-01-01

This work develops a model for design and realisation of profitability's and feasibility studies of a mining project. The model provides the structure of various necessary procedures to establish the feasibility studies and presents a logical system of task sequencing and information circulating between tasks. The specifications of mining projects, particularly their duration, complexity and high costs, necessitate design and realisation of feasibility study bases on the sufficient understanding of task behaviour and the critical path method view. For this purpose, critical paths with the highest frequency of occurrence were studied through several simulations. In addition, the critical tasks and sub tasks with the most probability were identified. The model introduced in this paper can serve as a perfect tool in feasibility study of a mining project. It can also be used as a basis of future development of mining software

Enhancing Survivorship Care Planning for Patients With Localized Prostate Cancer Using a Couple-Focused mHealth Symptom Self-Management Program: Protocol for a Feasibility Study.

Science.gov (United States)

Song, Lixin; Dunlap, Kaitlyn L; Tan, Xianming; Chen, Ronald C; Nielsen, Matthew E; Rabenberg, Rebecca L; Asafu-Adjei, Josephine K; Koontz, Bridget F; Birken, Sarah A; Northouse, Laurel L; Mayer, Deborah K

2018-02-26

This project explores a new model of care that enhances survivorship care planning and promotes health for men with localized prostate cancer transitioning to posttreatment self-management. Survivorship care planning is important for patients with prostate cancer because of its high incidence rate in the United States, the frequent occurrence of treatment-related side effects, and reduced quality of life (QOL) for both men and their partners. A key component of comprehensive survivorship care planning is survivorship care plans (SCPs), documents that summarize cancer diagnosis, treatment, and plans for follow-up care. However, research concerning the effectiveness of SCPs on patient outcomes or health service use has thus far been inconclusive. SCPs that are tailored to individual patients' needs for information and care may improve effectiveness. This study aims to examine the feasibility of an enhanced survivorship care plan (ESCP) that integrates a symptom self-management mHealth program called Prostate Cancer Education and Resources for Couples (PERC) into the existing standardized SCP. The specific aims are to (1) examine the feasibility of delivering ESCPs and (2) to estimate the magnitude of benefit of ESCPs. We will use a two-group randomized controlled pretest-posttest design and collect data at baseline (T1) and 4 months later (T2) among 50 patients completing initial treatment for localized prostate cancer and their partners. First, we will assess the feasibility of ESCP by recruitment, enrollment, and retention rates; program satisfaction with the ESCP; and perceived ease of use of the ESCP. To achieve the secondary aim, we will compare the ESCP users with the standardized SCP users and assess their primary outcomes of QOL (overall, physical, emotional, and social QOL); secondary outcomes (reduction in negative appraisals and improvement in self-efficacy, social support, and health behaviors to manage symptoms); and number of visits to posttreatment

White Earth Biomass/Biogas Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Triplett, Michael

2015-03-12

The White Earth Nation examined the feasibility of cost savings and fossil energy reduction through the installation of biogas/biomass boiler at the tribal casino. The study rejected biogas options due to availability and site constraints, but found a favorable environment for technical and financial feasibility of installing a 5 MMBtu hot water boiler system to offset 60-70 percent of current fuel oil and propane usage.

Technical feasibility study of 60 MWe fast reactor concept: RAPID

International Nuclear Information System (INIS)

Kambe, Mitsuru; Ueda, Nobuyuki; Uotani, Masaki

1993-01-01

A study has been performed on the passive safety features and technical feasibility of an inherently safe 60 MWe fast reactor concept RAPID to meet various power requirements in Japan. The system dynamic analyses on the UTOP and ULOF transients revealed that the enhanced reactivity feedback derived from an annular core configuration and the integrated fuel assembly provides a high margin of self-protection. Structural integrity of the integrated fuel assembly has also been confirmed. The following innovative key technologies have been demonstrated; Lithium Injection Modules (LIM) for ultimate shutdown, Lithium Expansion Modulus (LEM) for inherent reactivity feedback and Void Leading Channel (VLC) for the sodium void worth reduction. (author)

Non-contrast-enhanced 4D MR angiography with STAR spin labeling and variable flip angle sampling: a feasibility study for the assessment of Dural Arteriovenous Fistula

Energy Technology Data Exchange (ETDEWEB)

Jang, Jinhee; Kim, Bom-yi; Choi, Hyun Seok; Jung, So-Lyung; Ahn, Kook-Jin; Kim, Bum-soo [The Catholic University of Korea, Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, Seoul (Korea, Republic of); Schmitt, Peter [Siemens AG, Healthcare Sector, Erlangen (Germany); Kim, Inseong; Paek, Munyoung [Siemens AG, Healthcare, Seoul (Korea, Republic of)

2014-04-15

This study aimed to evaluate the feasibility of non-contrast-enhanced 4D magnetic resonance angiography (NCE 4D MRA) with signal targeting with alternative radiofrequency (STAR) spin labeling and variable flip angle (VFA) sampling in the assessment of dural arteriovenous fistula (DAVF) in the transverse sinus. Nine patients underwent NCE 4D MRA for the evaluation of DAVF in the transverse sinus at 3 T. One patient was examined twice, once before and once after the interventional treatment. All patients also underwent digital subtraction angiography (DSA) and/or contrast-enhanced magnetic resonance angiography (CEMRA). For the acquisition of NCE 4D MRA, a STAR spin tagging method was used, and a VFA sampling was applied in the data readout module instead of a constant flip angle. Two readers evaluated the NCE 4D MRA data for the diagnosis of DAVF and its type with consensus. The results were compared with those from DSA and/or CEMRA. All patients underwent NCE 4D MRA without any difficulty. Among seven patients with patent DAVFs, all cases showed an early visualization of the transverse sinus on NCE 4D MRA. Except for one case, the type of DAVF of NCE 4D MRA was agreed with that of reference standard study. Cortical venous reflux (CVR) was demonstrated in two cases out of three patients with CVR. NCE 4D MRA with STAR tagging and VFA sampling is technically and clinically feasible and represents a promising technique for assessment of DAVF in the transverse sinus. Further technical developments should aim at improvements of spatial and temporal coverage. (orig.)

Non-contrast-enhanced 4D MR angiography with STAR spin labeling and variable flip angle sampling: a feasibility study for the assessment of Dural Arteriovenous Fistula

International Nuclear Information System (INIS)

Jang, Jinhee; Kim, Bom-yi; Choi, Hyun Seok; Jung, So-Lyung; Ahn, Kook-Jin; Kim, Bum-soo; Schmitt, Peter; Kim, Inseong; Paek, Munyoung

2014-01-01

This study aimed to evaluate the feasibility of non-contrast-enhanced 4D magnetic resonance angiography (NCE 4D MRA) with signal targeting with alternative radiofrequency (STAR) spin labeling and variable flip angle (VFA) sampling in the assessment of dural arteriovenous fistula (DAVF) in the transverse sinus. Nine patients underwent NCE 4D MRA for the evaluation of DAVF in the transverse sinus at 3 T. One patient was examined twice, once before and once after the interventional treatment. All patients also underwent digital subtraction angiography (DSA) and/or contrast-enhanced magnetic resonance angiography (CEMRA). For the acquisition of NCE 4D MRA, a STAR spin tagging method was used, and a VFA sampling was applied in the data readout module instead of a constant flip angle. Two readers evaluated the NCE 4D MRA data for the diagnosis of DAVF and its type with consensus. The results were compared with those from DSA and/or CEMRA. All patients underwent NCE 4D MRA without any difficulty. Among seven patients with patent DAVFs, all cases showed an early visualization of the transverse sinus on NCE 4D MRA. Except for one case, the type of DAVF of NCE 4D MRA was agreed with that of reference standard study. Cortical venous reflux (CVR) was demonstrated in two cases out of three patients with CVR. NCE 4D MRA with STAR tagging and VFA sampling is technically and clinically feasible and represents a promising technique for assessment of DAVF in the transverse sinus. Further technical developments should aim at improvements of spatial and temporal coverage. (orig.)

Delayed gadolinium-enhanced MRI of the fibrocartilage disc of the temporomandibular joint – a feasibility study

Science.gov (United States)

Pittschieler, Elisabeth; Szomolanyi, Pavol; Schmid-Schwap, Martina; Weber, Michael; Egerbacher, Monika; Traxler, Hannes; Trattnig, Siegfried

2014-01-01

Objective To 1) test the feasibility of delayed Gadolinium-Enhanced Magnetic Resonance Imaging of Cartilage (dGEMRIC) at 3 T in the temporomandibular joint (TMJ) and 2) to determine the optimal delay for measurements of the TMJ disc after i.v. contrast agent (CA) administration. Design MRI of the right and left TMJ of six asymptomatic volunteers was performed at 3 T using a dedicated coil. 2D inversion recovery (2D-IR) sequences were performed at 4 time points covering 120 minutes and 3D gradient-echo (3D GRE) dual flip-angle sequences were performed at 14 time points covering 130 minutes after the administration of 0.2 mmol/kg of Gd-diethylenetriamine pentaacetic acid ion (Gd-DTPA)2-, i.e., 0.4 mL of Magnevist™ per kg body weight. Pair-wise tests were used to assess differences between pre-and post-contrast T1 values. Results 2D-IR sequences showed a statistically significant drop (p fibrocartilage disc of the TMJ. The recommended measurement time for dGEMRIC in the TMJ after i.v. CA administration is from 60 to 120 minutes. PMID:25131629

Peristalsis gap sign at cine magnetic resonance imaging for diagnosing strangulated small bowel obstruction. Feasibility study

International Nuclear Information System (INIS)

Takahara, Taro; Kwee, T.C.; Haradome, Hiroki

2011-01-01

The aim of this study was to determine the feasibility of cine magnetic resonance imaging (MRI) for diagnosing strangulated small bowel obstruction (SBO). This study included 38 patients with clinically confirmed SBO who had undergone cine MRI. Cine MRI scans were evaluated regarding the presence of the 'peristalsis gap sign' (referring to an akinetic or severely hypokinetic closed loop), indicating strangulation. Computed tomography (CT) was performed in 34 of 38 patients with (n=25) or without (n=9) contrast enhancement. CT images were evaluated using a combination of criteria (presence of hyperattenuation, poor contrast enhancement, mesenteric edema, wall thickening, massive ascites) indicating strangulation. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of cine MRI and CT for the diagnosis of strangulation were calculated and compared using surgical findings and the clinical course as the reference standard. Sensitivity, specificity, PPV, and NPV of cine MRI were 100%, 92.9%, 83.3%, and 100%, respectively; and those of CT (of which 26.5% was performed without contrast enhancement) were 66.7%, 92.0%, 75.0%, and 88.5%, respectively. There was no significant difference in diagnostic accuracy between the two methods (P=0.375). Cine MRI is a feasible and promising technique for diagnosing strangulation. (author)

Human reliability data bank: feasibility study

International Nuclear Information System (INIS)

Comer, K.; Miller, D.P.; Donovan, M.

1984-01-01

The US Nuclear Regulatory Commission and Sandia National Laboratories have been developing a plan for a human reliability data bank since August 1981. This research is in response to the data needs of the nuclear power industry's probabilistic risk assessment community. The three phases of the program are to: (A) develop the data bank concept, (B) develop an implementation plan and conduct a feasibility study, and (C) assist a sponsor in implementing the data bank. The program is now in Phase B. This paper describes the methods used in the feasibility study. Decisions to be made in the future regarding full-scale implementation will be based, in part, on the outcome of this study. 3 references, 2 figures

Gasohol: economic feasibility study. Final report

Energy Technology Data Exchange (ETDEWEB)

David, M. L.; Hammaker, G. S.; Buzenberg, R. J.; Wagner, J. P.

1978-07-01

This report was prepared by Development Planning and Research Associates, Inc. under a contract with the Energy Research and Development Center of the University of Nebraska in cooperation with the Agricultural Products Industrial Utilization Committee and the State of Nebraska. Funding for this study was provided to the Energy Research and Development Center by the U.S. Department of Energy and the Old West Regional Commission. The primary objective of the study was to: determine the fiscal and market conditions under which the production of gasohol would be profitable for private producers. For purposes of this study, gasohol is a motor fuel consisting of 10 percent agriculturally-derived anhydrous ethanol and 90 percent unleaded gasoline. The study assumes that gasohol can be a fuel substitute for gasoline; indeed, the cost of gasoline will significantly influence that for gasohol. Gasoline prices are determined by factors external to ethanol; thus, the economic feasibility study of gasohol is in large part an economic feasibility study of fuel-grade ethanol production. More specifically, the study examined the following: the technical aspects of distributing, marketing, and using gasohol; the costs of the distribution and marketing of ethanol and gasohol; the energy balance of ethanol production; the cost of producing ethanol; the factors influencing ehtanol plant size and location; and the conditions that would make ethanol economicaly feasible for private producers.

Feasibility and Pilot Studies in Palliative Care Research: A Systematic Review.

Science.gov (United States)

Jones, Terry A; Olds, Timothy S; Currow, David C; Williams, Marie T

2017-07-01

Feasibility and pilot study designs are common in palliative care research. Finding standard guidelines on the structure and reporting of these study types is difficult. In feasibility and pilot studies in palliative care research, to determine 1) how commonly a priori feasibility are criteria reported and whether results are subsequently reported against these criteria? and 2) how commonly are participants' views on acceptability of burden of the study protocol assessed? Four databases (OVID Medline, EMBASE, CINAHL, and PubMed via caresearch.com.au.) were searched. Search terms included palliative care, terminal care, advance care planning, hospice, pilot, feasibility, with a publication date between January 1, 2012 and December 31, 2013. Articles were selected and appraised by two independent reviewers. Fifty-six feasibility and/or pilot studies were included in this review. Only three studies had clear a priori criteria to measure success. Sixteen studies reported participant acceptability or burden with measures. Forty-eight studies concluded feasibility. The terms "feasibility" and "pilot" are used synonymously in palliative care research when describing studies that test for feasibility. Few studies in palliative care research outline clear criteria for success. The assessment of participant acceptability and burden is uncommon. A gold standard for feasibility study design in palliative care research that includes both clear criteria for success and testing of the study protocol for participant acceptability and burden is needed. Such a standard would assist with consistency in the design, conduct and reporting of feasibility and pilot studies. Copyright © 2017 American Academy of Hospice and Palliative Medicine. Published by Elsevier Inc. All rights reserved.

General discussion of feasibility study

International Nuclear Information System (INIS)

Calori, F.

1976-01-01

Fundamentals, objectives and parameters of feasibility studies in the field of nuclear power project planning are discussed in a general way. Technical and economic problems to be considered are pointed out. In special cases, IAEA offers its aid and support. (UA) [de

Feasibility of introducing ferromagnetic materials to onboard bulk high-Tc superconductors to enhance the performance of present maglev systems

Science.gov (United States)

Deng, Zigang; Wang, Jiasu; Zheng, Jun; Zhang, Ya; Wang, Suyu

2013-02-01

Performance improvement is a long-term research task for the promotion of practical application of promising high-temperature superconducting (HTS) magnetic levitation (maglev) vehicle technologies. We studied the feasibility to enhance the performance of present HTS Maglev systems by introducing ferromagnetic materials to onboard bulk superconductors. The principle here is to make use of the high magnetic permeability of ferromagnetic materials to alter the flux distribution of the permanent magnet guideway for the enhancement of magnetic field density at the position of the bulk superconductors. Ferromagnetic iron plates were added to the upper surface of bulk superconductors and their geometric and positioning effects on the maglev performance were investigated experimentally. Results show that the guidance performance (stability) was enhanced greatly for a particular setup when compared to the present maglev system which is helpful in the application where large guidance forces are needed such as maglev tracks with high degrees of curves.

Assessment of apical periodontitis by MRI. A feasibility study

Energy Technology Data Exchange (ETDEWEB)

Geibel, M.A. [Ulm Univ. (Germany). Oral and Maxillofacial Surgery; Schreiber, E.S.; Bracher, A.K.; Rasche, V. [Ulm Univ. (Germany). Internal Medicine II; Hell, E.; Ulrici, J. [Sirona Dental Systems GmbH, Bensheim (Germany). Dental Imaging; Sailer, L.K. [DOC Praxisklinik im Wiley, Neu-Ulm (Germany). MKG; Ozpeynirci, Y. [Ulm Univ. (Germany). Diagnostic and Interventional Radiology

2015-04-15

The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility study. Periapical lesions were defined as periapical radiolucencies (CBCT) or structural changes in the spongy bone signal (MRI), which were connected with the apical part of a root and with at least twice the width of the periodontal ligament space. The location and dimension of the lesions were compared between MRI and CBCT. While mainly mineralized tissue components such as teeth and bone were visible with CBCT, complimentary information of the soft tissue components was assessable with MRI. The MRI images provided sufficient diagnostic detail for the assessment of the main structures of interest. Heterogeneous contrast was observed within the lesion, with often a clear enhancement close to the apical foramen and the periodontal gap. No difference for lesion visibility was observed between MRI and CBCT. The lesion dimensions corresponded well, but were slightly but significantly overestimated with MRI. A heterogeneous lesion appearance was observed in several patients. Four patients presented with a well circumscribed hyperintense signal in the vicinity of the apical foramen. The MRI capability of soft tissue characterization may facilitate detailed analysis of periapical lesions. This clinical study confirms the applicability of multi-contrast MRI for the identification of periapical lesions.

Assessment of apical periodontitis by MRI. A feasibility study

International Nuclear Information System (INIS)

Geibel, M.A.; Schreiber, E.S.; Bracher, A.K.; Rasche, V.; Hell, E.; Ulrici, J.; Sailer, L.K.; Ozpeynirci, Y.

2015-01-01

The purpose of this clinical feasibility study was to evaluate the applicability of magnetic resonance imaging (MRI) for the assessment of apical periodontitis in direct comparison with cone beam CT (CBCT). 19 consecutive patients (average age 43 ± 13 years) with 34 lesions in total (13 molars, 14 premolars and 7 front teeth) were enrolled in this feasibility study. Periapical lesions were defined as periapical radiolucencies (CBCT) or structural changes in the spongy bone signal (MRI), which were connected with the apical part of a root and with at least twice the width of the periodontal ligament space. The location and dimension of the lesions were compared between MRI and CBCT. While mainly mineralized tissue components such as teeth and bone were visible with CBCT, complimentary information of the soft tissue components was assessable with MRI. The MRI images provided sufficient diagnostic detail for the assessment of the main structures of interest. Heterogeneous contrast was observed within the lesion, with often a clear enhancement close to the apical foramen and the periodontal gap. No difference for lesion visibility was observed between MRI and CBCT. The lesion dimensions corresponded well, but were slightly but significantly overestimated with MRI. A heterogeneous lesion appearance was observed in several patients. Four patients presented with a well circumscribed hyperintense signal in the vicinity of the apical foramen. The MRI capability of soft tissue characterization may facilitate detailed analysis of periapical lesions. This clinical study confirms the applicability of multi-contrast MRI for the identification of periapical lesions.

Feasibility of using high-definition transcranial direct current stimulation (HD-tDCS) to enhance treatment outcomes in persons with aphasia.

Science.gov (United States)

Richardson, Jessica; Datta, Abhishek; Dmochowski, Jacek; Parra, Lucas C; Fridriksson, Julius

2015-01-01

Transcranial direct current stimulation (tDCS) enhances treatment outcomes post-stroke. Feasibility and tolerability of high-definition (HD) tDCS (a technique that increases current focality and intensity) for consecutive weekdays as an adjuvant to behavioral treatment in a clinical population has not been demonstrated. To determine HD-tDCS feasibility outcomes: 1) ability to implement study as designed, 2) acceptability of repeated HD-tDCS administration to patients, and 3) preliminary efficacy. Eight patients with chronic post-stroke aphasia participated in a randomized crossover trial with two arms: conventional sponge-based (CS) tDCS and HD-tDCS. Computerized anomia treatment was administered for five consecutive days during each treatment arm. Individualized modeling/targeting procedures and an 8-channel HD-tDCS device were developed. CS-tDCS and HD-tDCS were comparable in terms of implementation, acceptability, and outcomes. Naming accuracy and response time improved for both stimulation conditions. Change in accuracy of trained items was numerically higher (but not statistically significant) for HD-tDCS compared to CS-tDCS for most patients. Regarding feasibility, HD-tDCS treatment studies can be implemented when designed similarly to documented CS-tDCS studies. HD-tDCS is likely to be acceptable to patients and clinicians. Preliminary efficacy data suggest that HD-tDCS effects, using only 4 electrodes, are at least comparable to CS-tDCS.

Application of Sodium Ligno Sulphonate as Surfactant in Enhanced Oil Recovery and Its Feasibility Test for TPN 008 Oil

Science.gov (United States)

Prakoso, N. I.; Rochmadi; Purwono, S.

2018-04-01

One of enhanced oil recovery (EOR) methods is using surfactants to reduce the interfacial tension between the injected fluid and the oil in old reservoir. The most important principle in enhanced oil recovery process is the dynamic interaction of surfactants with crude oil. Sodium ligno sulphonate (SLS) is a commercial surfactant and already synthesized from palm solid waste by another researcher. This work aimed to apply SLS as a surfactant for EOR especially in TPN 008 oil from Pertamina Indonesia. In its application as an EOR’s surfactant, SLS shall be passed feasibility test like IFT, thermal stability, compatibility, filtration, molecular weight, density, viscosity and pH tests. The feasibility test is very important for a preliminary test prior to another advanced test. The results demonstrated that 1% SLS solution in formation water (TPN 008) had 0.254 mN/M IFT value and was also great in thermal stability, compatibility, filtration, molecular weight, viscosity and pH test.

Technical design aspects of Feasibility Study-II

International Nuclear Information System (INIS)

Zisman, Michael S.

2001-01-01

Feasibility Study-II examined a high-performance Neutrino Factory providing 1 x 10 20 neutrinos per year aimed at a long-baseline detector. The Study was sponsored jointly by BNL and the Neutrino Factory and Muon Collider Collaboration ration (MC) and is based on a 1 MW proton driver operating at 24 GeV, i.e., an upgraded version of the AGS accelerator. Compared with the earlier FNAL-sponsored study (Feasibility Study-I), there is a sixfold improvement in performance. Here we describe details of the implementation of Study-II concepts and discuss their efficacy. Alternative approaches that will be pursued in follow-on R and D activities are also described briefly

A technology-enabled adherence enhancement system for people with bipolar disorder: results from a feasibility and patient acceptance analysis

Directory of Open Access Journals (Sweden)

Sajatovic M

2015-06-01

Full Text Available Martha Sajatovic,1 Michael S Davis,2 Kristin A Cassidy,3 Joseph Nestor,2 Johnny Sams,3 Edna Fuentes-Casiano3 1Department of Psychiatry and Neurological and Behavioral Outcomes Center, Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, Cleveland, OH, USA; 2MedicaSafe, New York, NY, USA; 3Department of Psychiatry, Case Western Reserve University School of Medicine, University Hospitals Case Medical Center, Cleveland, OH, USA Objective: As poor medication adherence is common in bipolar disorder (BD, technology-assisted approaches may help to monitor and enhance adherence. This study evaluated preliminary feasibility, patient satisfaction and effects on adherence, BD knowledge, and BD symptoms associated with the use of a multicomponent technology-assisted adherence enhancement system. Methods: This prospective study tested the system in five BD patients over a 15-day period. System components included: 1 an automated pill cap with remote monitoring sensor; 2 a multimedia adherence enhancement program; and 3 a treatment incentive program. This study evaluated system usability, patient satisfaction and effects on adherence (Morisky scale, knowledge (treatment knowledge test [TKT], and symptoms (internal state scale [ISS]. Results: Mean age of the sample was 62 years, 4/5 (80% Caucasian, and 4/5 (80% single/divorced or widowed. Most participants (4/5, 80% were on a single BD medication. Participants had BD for an average of 21 years. Challenges included attaching the pill sensor to standard pharmacy bottles for individuals using very large pill containers or those with multiday pill boxes. Three of five (60% individuals completed the full 15-day period. Usability scores were high overall. Mean Morisky scores improved. Means on all four subscales of the ISS were all in the direction of improvement. On the TKT, there was a 40% increase in mean scores. Conclusion: A multicomponent technology-assisted BD

Conceptual Thermal Treatment Technologies Feasibility Study

International Nuclear Information System (INIS)

Suer, A.

1996-01-01

This report presents a conceptual Thermal Treatment Technologies Feasibility Study (FS) for the Savannah River Site (SRS) focusing exclusively on thermal treatment technologies for contaminated soil, sediment, or sludge remediation projects

Feasibility of peer assessment and clinical audit to self-regulate the quality of physiotherapy services: a mixed methods study

NARCIS (Netherlands)

Maas, M.J.M.; Nijhuis-Van der Sanden, M.W.G.; Driehuis, F.; Heerkens, Y.F.; Vleuten, C.P.M. van der; Wees, P.J. van der

2017-01-01

OBJECTIVES: To evaluate the feasibility of a quality improvement programme aimed to enhance the client-centeredness, effectiveness and transparency of physiotherapy services by addressing three feasibility domains: (1) acceptability of the programme design, (2) appropriateness of the implementation

Feasibility study on large pool-type LMFBR

International Nuclear Information System (INIS)

1984-01-01

A feasibility study has been conducted from 1981 FY to 1983 FY, in order to evaluate the feasibility of a large pool-type LMFBR under the Japanese seismic design condition and safety design condition, etc. This study was aimed to establish an original reactor structure concept which meets those design conditions especially required in Japan. In the first year, preceding design concepts had been reviewed and several concepts were originated to be suitable to Japan. For typical two of them being selected by preliminary analysis, test programs were planned. In the second year, more than twenty tests with basic models had been conducted under severe conditions, concurrently analytical approaches were promoted. In the last year, larger model tests were conducted and analytical methods have been verified concerning hydrodynamic effects on structure vibration, thermo-hydraulic behaviours in reactor plena and so on. Finally the reactor structure concepts for a large pool-type LMFBR have been acknowledged to be feasible in Japan. (author)

Dual-gated cardiac PET-clinical feasibility study

Energy Technology Data Exchange (ETDEWEB)

Teraes, Mika; Kokki, Tommi; Noponen, Tommi; Hoppela, Erika; Sipilae, Hannu T.; Knuuti, Juhani [Turku PET Centre, PO BOX 52, Turku (Finland); Durand-Schaefer, Nicolas [General Electric Medical Systems, Buc (France); Pietilae, Mikko [Turku University Hospital, Department of Internal Medicine, Turku (Finland); Kiss, Jan [Turku University Hospital, Department of Surgery, Turku (Finland)

2010-03-15

Both respiratory and cardiac motions reduce image quality in myocardial imaging. For accurate imaging of small structures such as vulnerable coronary plaques, simultaneous cardiac and respiratory gating is warranted. This study tests the feasibility of a recently developed robust method for cardiac-respiratory gating. List-mode data with triggers from respiratory and cardiac cycles are rearranged into dual-gated segments and reconstructed with standard algorithms of a commercial PET/CT scanner. Cardiac gates were defined as three fixed phases and one variable diastolic phase. Chest motion was measured with a respiratory gating device and post-processed to determine gates. Preservation of quantification in dual-gated images was tested with an IEC whole-body phantom. Minipig and human studies were performed to evaluate the feasibility of the method. In minipig studies, a coronary catheter with radioactive tip was guided in coronary artery for in vivo and ex vivo acquisitions. Dual gating in humans with suspected cardiac disorders was performed using 18-F-FDG as a tracer. The method was found feasible for in vivo imaging and the radioactive catheter tip was better resolved in gated images. In human studies, the dual gating was found feasible and easy for clinical routine. Maximal movement of myocardial surface in cranio-caudal direction was over 20 mm. The shape of myocardium was clearly different between the gates and papillary muscles become more visible in diastolic images. The first clinical experiences using robust cardiac-respiratory dual gating are encouraging. Further testing in larger clinical populations using tracers designed especially for plaque imaging is warranted. (orig.)

Dual-gated cardiac PET-clinical feasibility study

International Nuclear Information System (INIS)

Teraes, Mika; Kokki, Tommi; Noponen, Tommi; Hoppela, Erika; Sipilae, Hannu T.; Knuuti, Juhani; Durand-Schaefer, Nicolas; Pietilae, Mikko; Kiss, Jan

2010-01-01

Both respiratory and cardiac motions reduce image quality in myocardial imaging. For accurate imaging of small structures such as vulnerable coronary plaques, simultaneous cardiac and respiratory gating is warranted. This study tests the feasibility of a recently developed robust method for cardiac-respiratory gating. List-mode data with triggers from respiratory and cardiac cycles are rearranged into dual-gated segments and reconstructed with standard algorithms of a commercial PET/CT scanner. Cardiac gates were defined as three fixed phases and one variable diastolic phase. Chest motion was measured with a respiratory gating device and post-processed to determine gates. Preservation of quantification in dual-gated images was tested with an IEC whole-body phantom. Minipig and human studies were performed to evaluate the feasibility of the method. In minipig studies, a coronary catheter with radioactive tip was guided in coronary artery for in vivo and ex vivo acquisitions. Dual gating in humans with suspected cardiac disorders was performed using 18-F-FDG as a tracer. The method was found feasible for in vivo imaging and the radioactive catheter tip was better resolved in gated images. In human studies, the dual gating was found feasible and easy for clinical routine. Maximal movement of myocardial surface in cranio-caudal direction was over 20 mm. The shape of myocardium was clearly different between the gates and papillary muscles become more visible in diastolic images. The first clinical experiences using robust cardiac-respiratory dual gating are encouraging. Further testing in larger clinical populations using tracers designed especially for plaque imaging is warranted. (orig.)

Feasibility Study: New Knowledge Demands in Turbulent Business World

Science.gov (United States)

Sprice, Renate; Kirikova, Marite

Feasibility study is one of the early activities in information systems (IS) development when important decisions regarding choice among several possible systems development alternatives are to be made. In times of relatively stable business environment and waterfall model as a systems development approach, the role and methods of feasibility study where quite clear (Kendall and Kendall 1995). However, new software development methods and the necessity to develop more rapidly new IS or their parts may. challenge the possibility to evaluate project feasibility in the early stages of IS development.

A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

International Nuclear Information System (INIS)

Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung

2014-01-01

Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

A feasibility study of projection-based energy weighting based on a photon-counting detector in contrast-enhanced digital subtraction mammography: a simulation study

Energy Technology Data Exchange (ETDEWEB)

Choi, Sunghoon; Lee, Seungwan; Choi, Yuna; Kim, Heejoung [Yonsei University, Wonju (Korea, Republic of)

2014-06-15

Contrast media, such as iodine and gadolinium, are generally used in digital subtraction mammography to enhance the contrast between target and background materials. In digital subtraction mammography, where one image (with contrast medium) is subtracted from another (anatomical background) to facilitate visualization of the tumor structure, tumors can be more easily distinguished after the injection of a contrast medium. In order to have more an effective method to increase the contrast-to-noise ratio (CNR), we applied a projection-based energy-weighting method. The purpose of this study is to demonstrate the feasibility of using the projection-based energy-weighting method in digital subtraction mammography. Unlike some other previous studies, we applied the projection-based energy-weighting method to more practical mammography conditions by using the Monte Carlo method to simulate four different iodine solutions embedded in a breast phantom comprised of 50% adipose and 50% glandular tissues. We also considered an optimal tube voltage and anode/filter combination in digital iodine contrast media mammography in order to maximize the figure-of-merit (FOM). The simulated source energy was from 20 to 45 keV to prevent electronic noise and include the k-edge energy of iodine (33.2 keV). The results showed that the projection-based energy-weighting improved the CNR by factors of 1.05 - 1.86 compared to the conventionally integrated images. Consequently, the CNR of digital subtraction mammography images can be improved by using projection-based energy-weighting with photon-counting detectors.

COLD-SAT feasibility study safety analysis

Science.gov (United States)

Mchenry, Steven T.; Yost, James M.

1991-01-01

The Cryogenic On-orbit Liquid Depot-Storage, Acquisition, and Transfer (COLD-SAT) satellite presents some unique safety issues. The feasibility study conducted at NASA-Lewis desired a systems safety program that would be involved from the initial design in order to eliminate and/or control the inherent hazards. Because of this, a hazards analysis method was needed that: (1) identified issues that needed to be addressed for a feasibility assessment; and (2) identified all potential hazards that would need to be controlled and/or eliminated during the detailed design phases. The developed analysis method is presented as well as the results generated for the COLD-SAT system.

Feasibility study for PTV measurement using x-ray holography

International Nuclear Information System (INIS)

Uemura, Tomomasa; Yamamoto, Yasufumi; Murata, Shigeru; Nishio, Shigeru; Iguchi, Manabu; Uesugi, Kentaro

2005-01-01

Some X-ray imaging techniques are examined for a feasibility study for micro-PIV in this study. There are three X-ray imaging method, the absorption contrast method, the refraction contrast method, and the phase contrast method. The first one is a common method but its spatial resolution is rather poor. The 2nd method corresponds to the Schlieren method that utilizes refraction of parallel light. The characteristics of the method, edge enhancement, can be effective in extracting tracer images. The third method is a kind of holography methods, and this method can record fine tracer particles. Among the three methods, the second and the third method are seemed to be applicable to PIV imaging, and those methods need a parallel X-ray. The SPring-8, the synchrotron radiation facility in Harima, is utilized. There are some methods to realize phase contrast image, most of them requires ultra-high precision in optical alignment. In the present study, though a coherent source is indispensable, the simplest and robust holography method, the inline holography, is used to take phase contrast pictures. (author)

Dynamic contrast-enhanced breast MRI at 7 Tesla utilizing a single-loop coil: a feasibility trial.

Science.gov (United States)

Umutlu, Lale; Maderwald, Stefan; Kraff, Oliver; Theysohn, Jens M; Kuemmel, Sherko; Hauth, Elke A; Forsting, Michael; Antoch, Gerald; Ladd, Mark E; Quick, Harald H; Lauenstein, Thomas C

2010-08-01

The aim of this study was to assess the feasibility of dynamic contrast-enhanced ultra-high-field breast imaging at 7 Tesla. A total of 15 subjects, including 5 patients with histologically proven breast cancer, were examined on a 7 Tesla whole-body magnetic resonance imaging system using a unilateral linearly polarized single-loop coil. Subjects were placed in prone position on a biopsy support system, with the coil placed directly below the region of interest. The examination protocol included the following sequences: 1) T2-weighted turbo spin echo sequence; 2) six dynamic T1-weighted spoiled gradient-echo sequences; and 3) subtraction imaging. Contrast-enhanced T1-weighted imaging at 7 Tesla could be obtained at high spatial resolution with short acquisition times, providing good image accuracy and a conclusively good delineation of small anatomical and pathological structures. T2-weighted imaging could be obtained with high spatial resolution at adequate acquisition times. Because of coil limitations, four high-field magnetic resonance examinations showed decreased diagnostic value. This first scientific approach of dynamic contrast-enhanced breast magnetic resonance imaging at 7 Tesla demonstrates the complexity of ultra-high-field breast magnetic resonance imaging and countenances the implementation of further advanced bilateral coil concepts to circumvent current limitations from the coil and ultra-high-field magnetic strength. 2010 AUR. Published by Elsevier Inc. All rights reserved.

The environmental energy sector programme. Poland: Feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

The Danish Ministry of Energy has granted financial aid to the preparation of a feasibility study necessary for the procurement of a financial solution to the modernisation of the combined heat and power plant in the city of Zielona Gora.The overall objectives of the Feasibility Study are to: establish new efficient power capacity in the south-west region of Poland, increase the energy efficiency, reduce the impact on the environment, utilise the local natural gas available which cannot be used in the national gas grid and reduce the costs of energy supply.The specific objective of this feasibility study is to obtain the best possible financing of the erection of a new CPH plant in Zielona Gora. The plant shall be designed to utilise the local resources of natural gas and to supply heat to the district heating grid in accordance with long-term planning strategies. (EHS)

"Is Your Man Stepping Out?" An Online Pilot Study to Evaluate Acceptability of a Guide-Enhanced HIV Prevention Soap Opera Video Series and Feasibility of Recruitment by Facebook Advertising.

Science.gov (United States)

Jones, Rachel; Lacroix, Lorraine J; Nolte, Kerry

2015-01-01

Love, Sex, and Choices (LSC) is a 12-episode soap opera video series developed to reduce HIV risk among at-risk Black urban women. We added a video guide commentator to offer insights at critical dramatic moments. An online pilot study evaluated acceptability of the Guide-Enhanced LSC (GELSC) and feasibility of Facebook advertising, streaming to smartphones, and retention. Facebook ads targeted high-HIV-prevalence areas. In 30 days, Facebook ads generated 230 screening interviews: 84 were high risk, 40 watched GELSC, and 39 followed up at 30 days. Recruitment of high-risk participants was 10 per week, compared to seven per week in previous field recruitment. Half the sample was Black; 12% were Latina. Findings suggest GELSC influenced sex scripts and behaviors. It was feasible to recruit young urban women from a large geographic area via Facebook and to retain the sample. We extended the reach to at-risk women by streaming to mobile devices. Copyright © 2015 Association of Nurses in AIDS Care. Published by Elsevier Inc. All rights reserved.

Eye-tracking computer systems for inpatients with tetraplegia: findings from a feasibility study.

Science.gov (United States)

van Middendorp, J J; Watkins, F; Park, C; Landymore, H

2014-12-02

Study design:A longitudinal, prospective, self-controlled cohort study.Objectives:To determine (1) the preliminary benefits of using eye-tracking computer systems (ETCSs) among inpatients with tetraplegia and (2) the feasibility of carrying out a well-powered randomized controlled trial.Setting:Specialist Spinal Cord Injuries Centre, United Kingdom; 6 months during 2013-2014.Methods:Individuals with tetraplegia who were admitted to the center and enrolled in this study were trained and allowed to use the ETCS (Tobii Eyegaze C15 System) twice a week for a duration of 10 weeks. Standardized training modules were developed and offered to all study participants. Study feasibility indicators as well as the Appraisals of Disability: Primary and Secondary Scale, Hospital Anxiety and Depression Scale and the Assistive Technology Device Predisposition Assessment questionnaire scores were taken before and after study enrollment.Results:A total of 31 inpatients with tetraplegia were screened. Although 14 patients (45%) met the study eligibility criteria, 6 patients (19%) consented to be enrolled in the study. Three participants did not complete the planned training schedule because of medical, technical and logistic reasons. Although half of the participants agreed that the ETCS under study was easy to use, no substantial improvements were seen in terms of psychological outcomes, appraisals of disability or independence.Conclusions:The conduct of a controlled trial evaluating the benefits of using ETCSs among newly injured patients with tetraplegia comes with considerable feasibility challenges. Until substantial technical improvements of ETCSs have been implemented, future research should initially focus on those individuals with tetraplegia who are living in the community and who have expressed a need to enhance their computer access and communication skills.Spinal Cord advance online publication, 2 December 2014; doi:10.1038/sc.2014.219.

[The development of care farming for elderly people with cognitive impairment to enhance social inclusion: A feasibility study of rice-farming care for elderly people with cognitive impairment].

Science.gov (United States)

Ura, Chiaki; Okamura, Tsuyoshi; Yamazaki, Sachiko; Ishiguro, Taichi; Ibe, Masumi; Miyazaki, Mayako; Torishima, Keisuke; Kawamuro, Yu

2018-01-01

The aim of this study was to assess the feasibility of rice-farming care among elderly people with cognitive impairment as a tool for social inclusion. Eight elderly individuals with cognitive impairment (7 men, 1 woman, mean age 68.3 years old) participated in the program over 25 weeks. The cognitive function, well-being, and depression were assessed before and after the program period. The degree of participants' independence during the program was also assessed. Semi-structured interviews with the participants and caregivers were held after the program period. The average participation rate was 93.0%. There were no unexpected events, and the subjects carried out farmwork almost independently. Regarding their well-being, two participants who scored below the cut-off criterion of mental health before the study scored above the cut-off after the study. Regarding depression, two participants who scored positive with a two-question case-finding instrument no longer scored positive after the study. Interviews with the participants showed that they enjoyed the program, especially because they had peers, a role, and gained positive emotions. Interviews with the caregivers showed that they had recognized for the first time what people can do with their skills. The results of the present study indicate that rice-farming was a feasible method of care with a positive impact on the well-being and depression of elderly people with cognitive impairment and enhanced their social participation, drawing out their individual strengths.

Radiation processing of flue gases: Guidelines for feasibility studies

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-12-01

The aim of this publication is to facilitate the performance of feasibility studies for Electron Beam flue gas cleanup projects by providing guidelines to conduct these studies and compiling information on the state of the art. This document summarizes the contents of a feasibility study; discusses the main items in plant construction, measurement and control systems, radiation safety and building construction; and lists the required economic data for internationally funded projects.

Radiation processing of flue gases: Guidelines for feasibility studies

International Nuclear Information System (INIS)

2000-12-01

The aim of this publication is to facilitate the performance of feasibility studies for Electron Beam flue gas cleanup projects by providing guidelines to conduct these studies and compiling information on the state of the art. This document summarizes the contents of a feasibility study; discusses the main items in plant construction, measurement and control systems, radiation safety and building construction; and lists the required economic data for internationally funded projects

Use of Active-Play Video Games to Enhance Aerobic Fitness in Schizophrenia: Feasibility, Safety, and Adherence.

Science.gov (United States)

Kimhy, David; Khan, Samira; Ayanrouh, Lindsey; Chang, Rachel W; Hansen, Marie C; Lister, Amanda; Ballon, Jacob S; Vakhrusheva, Julia; Armstrong, Hilary F; Bartels, Matthew N; Sloan, Richard P

2016-02-01

Active-play video games have been used to enhance aerobic fitness in various clinical populations, but their use among individuals with schizophrenia has been limited. Feasibility, acceptability, safety, and adherence data were obtained for use of aerobic exercise (AE) equipment by 16 individuals with schizophrenia during a 12-week AE program consisting of three one-hour exercise sessions per week. Equipment included exercise video games for Xbox 360 with Kinect motion sensing devices and traditional exercise equipment. Most participants (81%) completed the training, attending an average of 79% of sessions. The proportion of time spent playing Xbox (39%) exceeded time spent on any other type of equipment. When using Xbox, participants played 2.24±1.59 games per session and reported high acceptability and enjoyment ratings, with no adverse events. Measures of feasibility, acceptability, adherence, and safety support the integration of active-play video games into AE training for people with schizophrenia.

Feasibility study on small modular reactors for modern microgrids

Energy Technology Data Exchange (ETDEWEB)

Islam, R.; Gabbar, H.A., E-mail: hossam.gabbar@uoit.ca [Univ. of Ontario Inst. of Technology, Faculty of Energy Systems and Nuclear Science, Oshawa, Ontario (Canada)

2013-07-01

Microgrid is a solution of conventional power grid problem and offer sustainable decentralized power system. Microgrid with modern distributed energy resources (DER) could play an important role to alleviate dependency on the main electricity grid. Distributed energy resource comprises wind turbine, solar photovoltaic, diesel generator, gas engine, micro turbine, fuel cells, etc.Due to the gap between typical loads and supply within microgrid, larger scale energy generation could provide a possible solution to balance power demand and supply. Feasibility study of Small Nuclear Power Plant, such as Small Modular reactor (SMR), within microgrids could be achieved via different cases. To achieve the target, a comprehensive feasibility study is conducted on microgrid with SMR through electricity generation profiles, geographical and environmental assessment, as well as cost analysis using simulation practices and data analysis.Also potency of SMRs is analyzed. Parameters and Key Performance Indicators (KPIs) could be analyzed to achieve feasible solution of microgrids with small modular reactor (SMR) to improve the overall microgrid performance.The study shows that SMR could be a feasible solution if microgrid parameters are selected properly. (author)

Feasibility study on small modular reactors for modern microgrids

International Nuclear Information System (INIS)

Islam, R.; Gabbar, H.A.

2013-01-01

Microgrid is a solution of conventional power grid problem and offer sustainable decentralized power system. Microgrid with modern distributed energy resources (DER) could play an important role to alleviate dependency on the main electricity grid. Distributed energy resource comprises wind turbine, solar photovoltaic, diesel generator, gas engine, micro turbine, fuel cells, etc.Due to the gap between typical loads and supply within microgrid, larger scale energy generation could provide a possible solution to balance power demand and supply. Feasibility study of Small Nuclear Power Plant, such as Small Modular reactor (SMR), within microgrids could be achieved via different cases. To achieve the target, a comprehensive feasibility study is conducted on microgrid with SMR through electricity generation profiles, geographical and environmental assessment, as well as cost analysis using simulation practices and data analysis.Also potency of SMRs is analyzed. Parameters and Key Performance Indicators (KPIs) could be analyzed to achieve feasible solution of microgrids with small modular reactor (SMR) to improve the overall microgrid performance.The study shows that SMR could be a feasible solution if microgrid parameters are selected properly. (author)

Neurofeedback-Based Enhancement of Single Trial Auditory Evoked Potentials: Feasibility in Healthy Subjects.

Science.gov (United States)

Rieger, Kathryn; Rarra, Marie-Helene; Moor, Nicolas; Diaz Hernandez, Laura; Baenninger, Anja; Razavi, Nadja; Dierks, Thomas; Hubl, Daniela; Koenig, Thomas

2018-03-01

Previous studies showed a global reduction of the event-related potential component N100 in patients with schizophrenia, a phenomenon that is even more pronounced during auditory verbal hallucinations. This reduction assumingly results from dysfunctional activation of the primary auditory cortex by inner speech, which reduces its responsiveness to external stimuli. With this study, we tested the feasibility of enhancing the responsiveness of the primary auditory cortex to external stimuli with an upregulation of the event-related potential component N100 in healthy control subjects. A total of 15 healthy subjects performed 8 double-sessions of EEG-neurofeedback training over 2 weeks. The results of the used linear mixed effect model showed a significant active learning effect within sessions ( t = 5.99, P < .001) against an unspecific habituation effect that lowered the N100 amplitude over time. Across sessions, a significant increase in the passive condition ( t = 2.42, P = .03), named as carry-over effect, was observed. Given that the carry-over effect is one of the ultimate aims of neurofeedback, it seems reasonable to apply this neurofeedback training protocol to influence the N100 amplitude in patients with schizophrenia. This intervention could provide an alternative treatment option for auditory verbal hallucinations in these patients.

Feasibility of introducing ferromagnetic materials to onboard bulk high-Tc superconductors to enhance the performance of present maglev systems

International Nuclear Information System (INIS)

Deng, Zigang; Wang, Jiasu; Zheng, Jun; Zhang, Ya; Wang, Suyu

2013-01-01

Highlights: ► Ferromagnetic materials guide the flux distribution of the PMG to bulk positions. ► With ferromagnetic materials, guidance performance can be enhanced greatly. ► A new HTS Maglev system with onboard ferromagnetic materials is designed. ► The design can meet large guidance force requirements for practical applications. -- Abstract: Performance improvement is a long-term research task for the promotion of practical application of promising high-temperature superconducting (HTS) magnetic levitation (maglev) vehicle technologies. We studied the feasibility to enhance the performance of present HTS Maglev systems by introducing ferromagnetic materials to onboard bulk superconductors. The principle here is to make use of the high magnetic permeability of ferromagnetic materials to alter the flux distribution of the permanent magnet guideway for the enhancement of magnetic field density at the position of the bulk superconductors. Ferromagnetic iron plates were added to the upper surface of bulk superconductors and their geometric and positioning effects on the maglev performance were investigated experimentally. Results show that the guidance performance (stability) was enhanced greatly for a particular setup when compared to the present maglev system which is helpful in the application where large guidance forces are needed such as maglev tracks with high degrees of curves

Ultra low-dose of gadobenate dimeglumine for late gadolinium enhancement (LGE) imaging in acute myocardial infarction: A feasibility study

Energy Technology Data Exchange (ETDEWEB)

Galea, Nicola, E-mail: nicola.galea@uniroma1.it [Department of Radiological Sciences, Pathology and Oncology, Policlinico Umberto I, “Sapienza” University of Rome, Viale Regina Elena 315, 00161 Rome (Italy); Francone, Marco, E-mail: marco.francone@uniroma1.it [Department of Radiological Sciences, Pathology and Oncology, Policlinico Umberto I, “Sapienza” University of Rome, Viale Regina Elena 315, 00161 Rome (Italy); Zaccagna, Fulvio, E-mail: f.zaccagna@gmail.com [Department of Radiological Sciences, Pathology and Oncology, Policlinico Umberto I, “Sapienza” University of Rome, Viale Regina Elena 315, 00161 Rome (Italy); Ciolina, Federica, E-mail: federica.ciolina@gmail.com [Department of Radiological Sciences, Pathology and Oncology, Policlinico Umberto I, “Sapienza” University of Rome, Viale Regina Elena 315, 00161 Rome (Italy); Cannata, David, E-mail: davidrum@yahoo.it [Department of Radiological Sciences, Pathology and Oncology, Policlinico Umberto I, “Sapienza” University of Rome, Viale Regina Elena 315, 00161 Rome (Italy); Algeri, Emanuela, E-mail: emanuela_algeri@yahoo.com [Service de Radiologie et Imagerie Cardiovasculaire, Hôpital Cardiologique, Centre Hospitalier Régional et Universitaire de Lille, Avenue Oscar Lambret, 59037 Lille Cedex (France); Agati, Luciano, E-mail: luciano.agati@uniroma1.it [Department of Cardiovascular, Respiratory, Nephrologic, Anestesiologic and Geriatric Sciences, Sapienza University of Rome, Policlinico Umberto I, Via del Policlinico 165, 00161 Rome, Rome (Italy); and others

2014-12-15

Highlights: • We compared two gadolinium dose for late enhancement imaging in acute infarction. • We evaluated image quality both qualitatively and quantitatively. • Low dose regimen is feasible and provides better image quality at 5–10 min delay. • Standard dose warrants better image quality and should be routinely preferred. - Abstract: Purpose: To assess the feasibility of using an ultra-low dose (0.05 mmol/kg of body weight [BW]) of high relaxivity contrast agent for late gadolinium enhancement (LGE) imaging in patients with acute myocardial infarction (AMI). Materials and methods: 17 consecutive patients (mean age, 60.1 ± 10.3 years) with ST-segment elevation AMI underwent two randomized cardiac magnetic resonance studies (exam intervals between 24 and 48 h) on a 1.5 T unit during the first week after the event using gadobenate dimeglumine (Gd-BOPTA) at the dose of 0.1 mmol/kg BW (standard dose or SD group) and 0.05 mmol/kg BW (half dose or HD group). Image quality was qualitatively assessed. Quantitative analysis of LGE were performed by measuring signal intensity (SI), signal-to-noise ratio (SNR) in the infarcted myocardium (IM), non-infarcted myocardium (N-IM) and left ventricular cavity (LVC) in images acquired at 1, 3, 5, 10, 15 and 20 min after administration of Gd-BOPTA using both contrast media protocol. Contrast-to-noise ratio (CNR) between IM and N-IM (CNR IM/N-IM) and between IM and LVC (CNR IM/LVC) were also quantified for each time point. Moreover the extent of infarcted myocardium was measured. Results: 102 LGE images were evaluated for each dose group. Quality score was significantly higher for SD at 1, 15 and 20 min (0.002 < p < 0.046) and for HD at 5 min (p = 0.013). SNR has been higher in the SD group compared to the HD group even though not statistically significant at any time-point for both IM (SD vs. HD: 87.7 ± 73 vs. 65 ± 66; 0.15 < p < 0.38) and N-IM (SD vs. HD: 22 ± 61 vs. 9.9 ± 6.5; 0.09 < p < 0.43). LVC SNR was

TMI-2 fuel-recovery plant. Feasibility study

International Nuclear Information System (INIS)

Evans, D.L.

1982-12-01

This project is a feasibility study for constructing a TMI-2 core Fuel Recovery Plant at the Idaho National Engineering Laboratory (INEL). The primary objectives of the Fuel Recovery Plant (FRP) are to recover and account for the fuel and to process, isolate, and package the waste material from the TMI-2 core. This feasibility study is predicated on a baseline plant and covers its design, fabrication, installation, testing and operation. Alternative methods for the disposal of the TMI-2 core have also been considered, but not examined in detail for their feasibility. The FRP will receive TMI-2 fuel in canisters. The fuel will vary from core debris to intact fuel assemblies and include some core structural materials. The canister contents will be shredded and subsequently fed to a dissolver. Uranium, plutonium, fission products, and some core structural material will be dissolved. The uranium will be separated by solvent extraction and solidified by calcination. The plutonium will also be separated by solvent extraction and routed to the Plutonium Extraction Facility. The wastes will be packaged for further treatment, temporary storage or permanent disposal

Economic feasibility of a solar still desalination system with enhanced productivity

KAUST Repository

Ayoub, George M.

2014-02-01

Solar still desalination systems offer sustainable tools for fresh water production. However, their widespread application is often hindered by their relatively low production rates compared to other desalination methods. In this study, a simple amendment, in the form of a slowly-rotating hollow cylinder, was introduced within the solar still, significantly increasing the evaporative surface area. This new modified still was analyzed in terms of both operation and economic feasibility. The introduced cylinder resulted in a 200-300% increase in water output relative to a control, which did not include the cylinder. The resulting percent improvement far exceeds that obtained by other modifications. Unit production cost estimates varied between 6 and 60$/m3 depending on discount rates, productivity, service lifetime and initial capital costs. These projections are well within reported cost ranges for renewable-based technologies. In order to evaluate the system\\'s feasibility in real market value, different scenarios that introduce carbon-trading schemes and environmental degradation costs for fuel-based desalination, were performed. Reported costs for fuel-based brackish water and seawater desalination were thus adjusted to include unaccounted-for costs related to environmental damage. This analysis yielded results that further justify the economic feasibility of the new modified solar still, particularly for seawater desalination. © 2013 Elsevier B.V.

Steps to Enhance Early Recovery After Hematopoietic Stem Cell Transplantation: Lessons Learned From a Physical Activity Feasibility Study.

Science.gov (United States)

Hacker, Eileen Danaher; Peters, Tara; Patel, Pritesh; Rondelli, Damiano

This pilot study tested and refined a free-living physical activity intervention. The investigators evaluated the acceptability and feasibility of the intervention after hematopoietic stem cell transplantation and determined preliminary effects on physical activity, fatigue, muscle strength, functional ability, and quality of life. This pilot study used a 1-group, pretest-posttest design. The free-living physical activity intervention consisted of an education component and 6 weeks of gradually increasing physical activity after discharge from the hospital. The intervention was designed to increase steps by 10% weekly. Subjects were assessed before transplantation and during the seventh week after discharge from the hospital after completing the intervention. Pretest-posttest scores were analyzed with paired t tests. Subject wore the physical activity tracker for an average of 38 of 42 days and met their physical activity goals 57% of the time. Subjects reported significantly less physical fatigue after the free-living physical activity intervention compared with baseline (P = .05). Improvements in quality of life approached significance (P = .06). The findings demonstrate that the free-living physical activity intervention implemented during the very early recovery period after transplantation is feasible and acceptable. The intervention potentially reduces fatigue and improves quality of life. The positive results must be interpreted cautiously given the pilot nature of the study. The evidence supports continued investigation.

Ute Mountain Ute Tribe Community-Scale Solar Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Rapp, Jim [Parametrix; Knight, Tawnie [Ute Mountain Ute Tribe

2014-01-30

Parametrix Inc. conducted a feasibility study for the Ute Mountain Ute Tribe to determine whether or not a community-scale solar farm would be feasible for the community. The important part of the study was to find where the best fit for the solar farm could be. In the end, a 3MW community-scale solar farm was found best fit with the location of two hayfield sites.

“Is Your Man Stepping Out?” An online pilot study to evaluate acceptability of a guide-enhanced HIV prevention soap opera video series and feasibility of recruitment by Facebook© advertising

Science.gov (United States)

Jones, Rachel; Lacroix, Lorraine J.; Nolte, Kerry

2015-01-01

Love, Sex, and Choices (LSC) is a 12-episode soap opera video series developed to reduce HIV risk among at-risk Black urban women. We added a video guide commentator to offer insights at critical dramatic moments. An online pilot study evaluated acceptability of the Guide Enhanced LSC (GELSC) and feasibility of Facebook© advertising, streaming to smartphones, and retention. Facebook© ads targeted high HIV-prevalence areas. In 30 days, Facebook© ads generated 230 screening interviews; 84 were high risk, 40 watched GELSC, and 39 followed up at 30 days. Recruitment of high-risk participants was 10 per week compared to 7 per week in previous field recruitment. Half the sample was Black; 12% were Latina. Findings suggest GELSC influenced sex scripts and behaviors. It was feasible to recruit young urban women from a large geographic area via Facebook© and to retain the sample. We extended the reach to at-risk women by streaming to mobile devices. PMID:26066692

Feasibility of semiautomated MR volumetry using gadoxetic acid-enhanced MRI at hepatobiliary phase for living liver donors.

Science.gov (United States)

Lee, Jeongjin; Kim, Kyoung Won; Kim, So Yeon; Kim, Bohyoung; Lee, So Jung; Kim, Hyoung Jung; Lee, Jong Seok; Lee, Moon Gyu; Song, Gi-Won; Hwang, Shin; Lee, Sung-Gyu

2014-09-01

To assess the feasibility of semiautomated MR volumetry using gadoxetic acid-enhanced MRI at the hepatobiliary phase compared with manual CT volumetry. Forty potential live liver donor candidates who underwent MR and CT on the same day, were included in our study. Semiautomated MR volumetry was performed using gadoxetic acid-enhanced MRI at the hepatobiliary phase. We performed the quadratic MR image division for correction of the bias field inhomogeneity. With manual CT volumetry as the reference standard, we calculated the average volume measurement error of the semiautomated MR volumetry. We also calculated the mean of the number and time of the manual editing, edited volume, and total processing time. The average volume measurement errors of the semiautomated MR volumetry were 2.35% ± 1.22%. The average values of the numbers of editing, operation times of manual editing, edited volumes, and total processing time for the semiautomated MR volumetry were 1.9 ± 0.6, 8.1 ± 2.7 s, 12.4 ± 8.8 mL, and 11.7 ± 2.9 s, respectively. Semiautomated liver MR volumetry using hepatobiliary phase gadoxetic acid-enhanced MRI with the quadratic MR image division is a reliable, easy, and fast tool to measure liver volume in potential living liver donors. Copyright © 2013 Wiley Periodicals, Inc.

Decision tree analysis as a supplementary tool to enhance histomorphological differentiation when distinguishing human from non-human cranial bone in both burnt and unburnt states: A feasibility study.

Science.gov (United States)

Simmons, T; Goodburn, B; Singhrao, S K

2016-01-01

This feasibility study was undertaken to describe and record the histological characteristics of burnt and unburnt cranial bone fragments from human and non-human bones. Reference series of fully mineralized, transverse sections of cranial bone, from all variables and specimen states, were prepared by manual cutting and semi-automated grinding and polishing methods. A photomicrograph catalogue reflecting differences in burnt and unburnt bone from human and non-humans was recorded and qualitative analysis was performed using an established classification system based on primary bone characteristics. The histomorphology associated with human and non-human samples was, for the main part, preserved following burning at high temperature. Clearly, fibro-lamellar complex tissue subtypes, such as plexiform or laminar primary bone, were only present in non-human bones. A decision tree analysis based on histological features provided a definitive identification key for distinguishing human from non-human bone, with an accuracy of 100%. The decision tree for samples where burning was unknown was 96% accurate, and multi-step classification to taxon was possible with 100% accuracy. The results of this feasibility study strongly suggest that histology remains a viable alternative technique if fragments of cranial bone require forensic examination in both burnt and unburnt states. The decision tree analysis may provide an additional but vital tool to enhance data interpretation. Further studies are needed to assess variation in histomorphology taking into account other cranial bones, ontogeny, species and burning conditions. © The Author(s) 2015.

The SHIELD (Safety & Health Improvement: Enhancing Law Enforcement Departments Study: Feasibility and Findings

Directory of Open Access Journals (Sweden)

Kerry Stephen Kuehl

2014-05-01

Full Text Available This randomized prospective trial aimed to assess the feasibility and efficacy of a team-based worksite health and safety intervention for law enforcement personnel. Four-hundred and eight subjects were enrolled and half were randomized to meet participants met for weekly, peer-led sessions delivered from a scripted team-based health and safety curriculum. Curriculum addressed: exercise, nutrition, stress, sleep, body weight, injury, and other unhealthy lifestyle behaviours such as smoking and heavy alcohol use. Health and safety questionnaires administered before and after the intervention found significant improvements for increased fruit and vegetable consumption, overall healthy eating, increased sleep quantity and sleep quality, and reduced personal stress.

The Economic Pre-feasibility Study of Madura Nuclear Desalination System

International Nuclear Information System (INIS)

Djoko-Birmanto, Moch; Suparman

2004-01-01

The feasibility study is needed in the planning of construction of NPPs SMART type coupled with desalination technology of MED tpe to produce clean water in Madura island. One important part of the feasibility study is the economical and financial analysis. The feasibility criteria of nuclear desalination project is analyzed by using the general parameters that is commonly used in evaluating a project, which is Financial Net Present Value (FNPV), Financial Internal Rate of Return (FIRR) and Payback Period. The calculation result shows that with the electricity selling price of 54.17 mills/KWh, for entirely project funded by the foreign loan, local loan and equity, it could be obtained FIRR 12.73 %, FNPV US$ 75.29 million and Payback Period is 8 years. By seeing from the project feasibility criteria, this nuclear desalination project can be feasible and the investment aspect shows that this project is beneficial because the capital return rate is rather high, the benefit in the end of the economic life-time is rather big and the capital payback period is fast. (author)

The feasibility and accuracy of enhanced MR pulmonary perfusion imaging in evaluating therapeutic effect of pulmonary embolism

International Nuclear Information System (INIS)

Wang Nana; Lv Biao; Zhao Zhaoqi; Huang Xiaoyong; Lu Dongxu; Mi Hongzhi; Yu Weiyong

2010-01-01

Objective: To investigate the feasibility and accuracy of enhanced magnetic resonance pulmonary perfusion imaging (MRPP) in the diagnosis and follow-up of pulmonary embolism (PE). Methods: Sixty patients suspected of PE underwent MRPP. Twenty-seven patients also underwent radionuclide perfusion imaging. 22 patients repeated MRPP examination after 3 day to 1 month antieoagulation or thrombolytic therapy. The feasibility and accuracy of MRPP in the diagnosis and follow-up of PE were evaluated according to the transformation rate of signal (TROS), time-signal curve and some parameters of main pulmonary artery (such as peak value of flow, mean flow velocity and flow rate). The t test and rank sum test were used for the statistics. Results: MRPP showed a high agreement with radionuclide perfusion imaging. TROS was (2.86 ± 2.48) vs(6.72 ± 2.54) (t=3.370, P 0.05). Conclusion: MRPP shows a high agreement with radionuclide perfusion imaging and is a useful method for the diagnosis and follow-up of PE. (authors)

Sedimentary Geothermal Feasibility Study: October 2016

Energy Technology Data Exchange (ETDEWEB)

Augustine, Chad [National Renewable Energy Lab. (NREL), Golden, CO (United States); Zerpa, Luis [Colorado School of Mines, Golden, CO (United States)

2017-01-01

The objective of this project is to analyze the feasibility of commercial geothermal projects using numerical reservoir simulation, considering a sedimentary reservoir with low permeability that requires productivity enhancement. A commercial thermal reservoir simulator (STARS, from Computer Modeling Group, CMG) is used in this work for numerical modeling. In the first stage of this project (FY14), a hypothetical numerical reservoir model was developed, and validated against an analytical solution. The following model parameters were considered to obtain an acceptable match between the numerical and analytical solutions: grid block size, time step and reservoir areal dimensions; the latter related to boundary effects on the numerical solution. Systematic model runs showed that insufficient grid sizing generates numerical dispersion that causes the numerical model to underestimate the thermal breakthrough time compared to the analytic model. As grid sizing is decreased, the model results converge on a solution. Likewise, insufficient reservoir model area introduces boundary effects in the numerical solution that cause the model results to differ from the analytical solution.

Feasibility study on tandem fuel cycle

International Nuclear Information System (INIS)

Han, P.S.; Suh, I.S.; Rim, C.S.; Kim, B.K.; Suh, K.S.; Ro, S.K.; Juhn, P.I.; Kim, S.Y.

1983-01-01

The objective of this feasibility study is to review and assess the current state of technology concerning the tandem fuel cycle. Based on the results from this study, a long-term development plan suitable for Korea has been proposed for this cycle, i.e., the PWR → CANDU tandem fuel cycle which used plutonium and uranium, recovered from spent PWR fuel by co-processing, as fuel material for CANDU reactors. (Author)

Accuracy of contrast-enhanced spectral mammography for estimating residual tumor size after neoadjuvant chemotherapy in patients with breast cancer: a feasibility study.

Science.gov (United States)

Barra, Filipe Ramos; de Souza, Fernanda Freire; Camelo, Rosimara Eva Ferreira Almeida; Ribeiro, Andrea Campos de Oliveira; Farage, Luciano

2017-01-01

To assess the feasibility of contrast-enhanced spectral mammography (CESM) of the breast for assessing the size of residual tumors after neoadjuvant chemotherapy (NAC). In breast cancer patients who underwent NAC between 2011 and 2013, we evaluated residual tumor measurements obtained with CESM and full-field digital mammography (FFDM). We determined the concordance between the methods, as well as their level of agreement with the pathology. Three radiologists analyzed eight CESM and FFDM measurements separately, considering the size of the residual tumor at its largest diameter and correlating it with that determined in the pathological analysis. Interobserver agreement was also evaluated. The sensitivity, specificity, positive predictive value, and negative predictive value were higher for CESM than for FFDM (83.33%, 100%, 100%, and 66% vs. 50%, 50%, 50%, and 25%, respectively). The CESM measurements showed a strong, consistent correlation with the pathological findings (correlation coefficient = 0.76-0.92; intraclass correlation coefficient = 0.692-0.886). The correlation between the FFDM measurements and the pathological findings was not statistically significant, with questionable consistency (intraclass correlation coefficient = 0.488-0.598). Agreement with the pathological findings was narrower for CESM measurements than for FFDM measurements. Interobserver agreement was higher for CESM than for FFDM (0.94 vs. 0.88). CESM is a feasible means of evaluating residual tumor size after NAC, showing a good correlation and good agreement with pathological findings. For CESM measurements, the interobserver agreement was excellent.

A Feasibility study of a mining business

Directory of Open Access Journals (Sweden)

Cehlár Michal

2001-06-01

Full Text Available The economic evaluation of a project requires a great deal of diverse information to be brought together in one place. The greatest concern is that there will be an error by omission, so it is useful to have a detailed list of what one needs to know in order to make a thorough evaluation.There are various of detail required at the different stages of evaluation in the project, from the "quick and dirty" overview to the pre-feasibility study, through a full detailed feasibility study, to a due diligence review. This list addresses most of the economic variables in project and can be used at all levels of studies. Its purpose is to identify a variable or issue and to raise a question, which the review can pursue in more detail using an increasingly more comprehensive checklist for each topic. While developed from the point of view of a new project, this list is equally valid for an ongoing operation.A feasibility study is defined as an assessment of all aspects of a project including technical, infrastructural, environmental, social, legislative and commercial factors, which is sufficiently detailed to support a decision on the implementation. Each project has an associated level of risk. For a proposed investment to increase the value of a firm's stock, it should have a higher expected rate of return than shareholders require for assuming that risk. Since investors demand for a higher potential returns from a riskier project, the cost of capital depends on the venture's risk.

MacMillan Pier Transportation Center Feasibility Study.

Science.gov (United States)

2006-06-01

The MacMillan Pier Transportation Center Feasibility Study examines two potential sites (landside and waterside) for a transportation center that provides a range of tourist and traveler information. It would serve as a gateway for Provincetown and t...

Design approaches for enhancing the engineering feasibility of tokamak power reactors

International Nuclear Information System (INIS)

Shannon, T.E.; Steiner, D.

1977-01-01

The design approach developed in the ORNL Fusion Power Demonstration Study is reviewed. The design concepts having greatest impact on reactor feasibility by the application of current or near term technology are described briefly. These are: blanket structural material, blanket coolant, power conversion system, and pulsed electrical system. Concepts relative to the approach taken to simplify the overall reactor design are listed

Feasibility study for siting of a deep repository within the Storuman municipality

International Nuclear Information System (INIS)

1995-01-01

It is SKB's task to gather a broad body of information for the siting of a deep repository for Sweden's spent nuclear fuel and other long-lived radioactive waste. The criteria presented by SKB serve as guidelines for the siting studies. Overviews of siting factors are compiled in general siting studies of all or parts of Sweden. Feasibility studies examine the siting prospects in potentially suitable and interested municipalities. SKB plans to carry out feasibility studies in five to ten municipalities in different parts of the country. General studies and feasibility studies are primarily based on existing material. The feasibility study in Storuman is the first to be conducted. It began during the second half of 1993 with the conclusion of an agreement between the municipality and SKB. SKB has been in charge of the execution of the feasibility study. SKB has been responsible for the summary provided in a status report published in June 1994, as well as for the conclusions and evaluations in this final report. Altogether about 30 reports have been published within the framework of the feasibility study. The purpose of the various studies have been to describe, in as much detail as possible, the prospects for siting a deep repository in the municipality of Storuman, and to shed light on the possible positive and negative consequences of such a siting. The feasibility study has led to a discussion within the municipality and the region concerning the siting of a deep repository. In SKB's opinion, this gives all those concerned ample opportunity to become acquainted with the issues and to assert their interests and present their viewpoints at an early stage. 55 refs

Quantification of manganese in human hand bones: a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Aslam; Pejovic-Milic, A; Chettle, D R; McNeill, F E [Department of Medical Physics and Applied Radiation Sciences, McMaster University, Hamilton, ON, L8S 4K1 (Canada)], E-mail: aslamib@mcmaster.ca

2008-08-07

Manganese is both an essential element to human health and also toxic when humans are exposed to excessive levels, particularly by means of inhalation. Biological monitoring of manganese exposure is problematic. It is subject to homeostasis; levels in blood (or serum/plasma) reflect only the most recent exposure and rapidly return to within normal ranges, even when there has been a temporary excursion in response to exposure. In this context, we have been developing a non-invasive technique for measurement of manganese stored in bone, using in vivo neutron activation analysis. Following preliminary feasibility studies, the technique has been enhanced by two significant infrastructure advances. A specially designed irradiation facility serves to maximize the activation of manganese with respect to the dose of ionizing radiation. Secondly, an array of eight NaI(Tl) crystals provides a detection system with very close to 4{pi} geometry. This feasibility study, using neutron activation analysis to measure manganese in the bones of the hand, takes two features into account. Firstly, there is considerable magnesium present in the bone and this produces a spectral interference with the manganese. The {sup 26}Mg(n,{gamma}){sup 27}Mg reaction produces {gamma}-rays of 0.843 MeV from the decay of {sup 27}Mg, which interfere with the 0.847 MeV {gamma}-rays from the decay of {sup 56}Mn, produced by the {sup 55}Mn(n,{gamma}){sup 56}Mn reaction. Secondly, this work provides estimates of the levels of manganese to be expected in referent subjects. A revised estimate has been made from the most recent literature to explore the potential of the technique as a suitable means of screening patients and people exposed to excessive amounts of Mn who could develop many-fold increased levels of Mn in bones as demonstrated through various animal studies. This report presents the enhancements to the neutron activation system, by which manganese can be measured, which resulted in a detection

Quantification of manganese in human hand bones: a feasibility study

International Nuclear Information System (INIS)

Aslam; Pejovic-Milic, A; Chettle, D R; McNeill, F E

2008-01-01

Manganese is both an essential element to human health and also toxic when humans are exposed to excessive levels, particularly by means of inhalation. Biological monitoring of manganese exposure is problematic. It is subject to homeostasis; levels in blood (or serum/plasma) reflect only the most recent exposure and rapidly return to within normal ranges, even when there has been a temporary excursion in response to exposure. In this context, we have been developing a non-invasive technique for measurement of manganese stored in bone, using in vivo neutron activation analysis. Following preliminary feasibility studies, the technique has been enhanced by two significant infrastructure advances. A specially designed irradiation facility serves to maximize the activation of manganese with respect to the dose of ionizing radiation. Secondly, an array of eight NaI(Tl) crystals provides a detection system with very close to 4π geometry. This feasibility study, using neutron activation analysis to measure manganese in the bones of the hand, takes two features into account. Firstly, there is considerable magnesium present in the bone and this produces a spectral interference with the manganese. The 26 Mg(n,γ) 27 Mg reaction produces γ-rays of 0.843 MeV from the decay of 27 Mg, which interfere with the 0.847 MeV γ-rays from the decay of 56 Mn, produced by the 55 Mn(n,γ) 56 Mn reaction. Secondly, this work provides estimates of the levels of manganese to be expected in referent subjects. A revised estimate has been made from the most recent literature to explore the potential of the technique as a suitable means of screening patients and people exposed to excessive amounts of Mn who could develop many-fold increased levels of Mn in bones as demonstrated through various animal studies. This report presents the enhancements to the neutron activation system, by which manganese can be measured, which resulted in a detection limit in the hand of human subjects of 1.6 �

Three Affliated Tribes Renewable Energy Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Belvin Pete; Kent Good; Krista Gordon; Ed McCarthy,

2006-05-26

The Three Affliated Tribes on the Fort Berthold Reservation studied the feasibility of a commercial wind facility on land selected and owned by the Tribes and examined the potential for the development of renewable energy resources on Tribal Lands.

Status of feasibility study for various technical options of FBR systems

International Nuclear Information System (INIS)

Kani, Yoshio

2000-01-01

JNC (Japan Nuclear Cycle Development Institute) has started a new research project of feasibility studies (F/S) for a wide variety option of fast breeder reactor (FBR) and related fuel cycle in order to develop an economically competitive FBR cycle system fro commercialization. JNC and the electric untilities in Japan have established a new organization in JNC to perform the F/S since July 1, 1999. The organization has undertaken feasibility studies (F/S) in order to determine promising FBR cycle concepts and define necessary RandD tasks. The long-term targets of commercialized FBR cycle system are set as ensuring safety, economic competitiveness relative to future LWRs, efficient utilization of resources, reduction in environmental burden, and enhancement of nuclear non-proliferation. This paper describes the progress of design studies for a wide variety of technical options of FBR plants in the framework of the F/S. We make efforts towards considering all key issues so as not to fail to notice the best concept in a commercialized stage. In the study of technical options, the identified coolant types are sodium, heavy metal (lead and lead-bismuth), gas (carbon dioxide and helium ) and water (boiling water, pressurized water and supercritical water). The classified types of fuel are mixed oxide, nitride and metal. Design studies of small size modular plant concepts are also performed. We study many reactor concepts in combination with a coolant type and a fuel type, understand characteristics of each reactor concept based on our experience and an extensive survey of literature, and make a draft design of each reactor concept for rough estimation of construction costs. We also check how far the concept accomplishes each index (safety, economy, resource utilization, etc.) of design requirements, and will select several promising reactor concepts. (author)

Restoring effective sleep tranquility (REST): A feasibility and pilot study.

Science.gov (United States)

Eakman, Aaron M; Schmid, Arlene A; Henry, Kimberly L; Rolle, Natalie R; Schelly, Catherine; Pott, Christine E; Burns, Joshua E

2017-06-01

The purpose of this pilot study was to establish the feasibility of completing a future controlled trial of a multi-component cognitive behavioral therapy for insomnia program for military veterans with sleep disturbance. This was a single-arm feasibility and pilot study. Participants were United States post-9/11 veterans with service-connected injuries, university students, and had self-reported sleep disturbances. Restoring Effective Sleep Tranquility was a multi-component cognitive behavioral therapy for insomnia intervention consisting of seven sessions of group therapy and eight 1:1 sessions delivered by occupational therapists. Feasibility and pilot indicators were process, resources, management, and scientific, including pre-post-assessments of sleep difficulties, dysfunctional sleep beliefs, participation, and pain interference. Indicators were supportive of feasibility, including reduced sleep difficulties (for example Medical Outcomes Study Sleep Measure [ t  = 3.29, p  = .02]), reduced nightmares: t  = 2.79, p  = .03; fewer dysfunctional sleep beliefs: t  = 3.63, p  = .01, and greater ability to participate in social roles: t  = -2.86, p  = .03, along with trends towards improved satisfaction with participation and reduced pain interference. The Restoring Effective Sleep Tranquility program may reduce sleep difficulties and improve participation in US veterans with service-connected injuries, and evidence indicates a controlled trial would be feasible to deliver.

Financial feasibility of a log sort yard handling small-diameter logs: A preliminary study

Science.gov (United States)

Han-Sup Han; E. M. (Ted) Bilek; John (Rusty) Dramm; Dan Loeffler; Dave Calkin

2011-01-01

The value and use of the trees removed in fuel reduction thinning and restoration treatments could be enhanced if the wood were effectively evaluated and sorted for quality and highest value before delivery to the next manufacturing destination. This article summarizes a preliminary financial feasibility analysis of a log sort yard that would serve as a log market to...

Feasibility Study on HYSOL CSP

DEFF Research Database (Denmark)

Nielsen, Lars Henrik; Baldini, Mattia; Skytte, Klaus

2016-01-01

integrated HYSOL concept, therefore, becomes a fully dispatchable (offering firm power) and fully renewable energy source (RES) based power supply alternative, offering CO2-free electricity in regions with sufficient solar resources. The economic feasibility of HYSOL configurations is addressed in this paper....... The CO2 free HYSOL alternative is discussed relative to conventional reference firm power generation technologies. In particular the HYSOL performance relative to new power plants based on natural gas (NG) such as open cycle or combined cycle gas turbines (OCGT or CCGT) are in focus. The feasibility...

Enhancing Care of Aged and Dying Prisoners: Is e-Learning a Feasible Approach?

Science.gov (United States)

Loeb, Susan J; Penrod, Janice; Myers, Valerie H; Baney, Brenda L; Strickfaden, Sophia M; Kitt-Lewis, Erin; Wion, Rachel K

Prisons and jails are facing sharply increased demands in caring for aged and dying inmates. Our Toolkit for Enhancing End-of-life Care in Prisons effectively addressed end-of-life (EOL) care; however, geriatric content was limited, and the product was not formatted for broad dissemination. Prior research adapted best practices in EOL care and aging; but, delivery methods lacked emerging technology-focused learning and interactivity. Our purposes were to uncover current training approaches and preferences and to ascertain the technological capacity of correctional settings to deliver computer-based and other e-learning training. An environmental scan was conducted with 11 participants from U.S. prisons and jails to ensure proper fit, in terms of content and technology capacity, between an envisioned computer-based training product and correctional settings. Environmental scan findings focused on content of training, desirable qualities of training, prominence of "homegrown" products, and feasibility of commercial e-learning. This study identified qualities of training programs to adopt and pitfalls to avoid and revealed technology-related issues to be mindful of when designing computer-based training for correctional settings, and participants spontaneously expressed an interest in geriatrics and EOL training using this learning modality as long as training allowed for tailoring of materials.

Feasibility study for siting of a deep repository within the Storuman municipality

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-01-01

It is SKB`s task to gather a broad body of information for the siting of a deep repository for Sweden`s spent nuclear fuel and other long-lived radioactive waste. The criteria presented by SKB serve as guidelines for the siting studies. Overviews of siting factors are compiled in general siting studies of all or parts of Sweden. Feasibility studies examine the siting prospects in potentially suitable and interested municipalities. SKB plans to carry out feasibility studies in five to ten municipalities in different parts of the country. General studies and feasibility studies are primarily based on existing material. The feasibility study in Storuman is the first to be conducted. It began during the second half of 1993 with the conclusion of an agreement between the municipality and SKB. SKB has been in charge of the execution of the feasibility study. SKB has been responsible for the summary provided in a status report published in June 1994, as well as for the conclusions and evaluations in this final report. Altogether about 30 reports have been published within the framework of the feasibility study. The purpose of the various studies have been to describe, in as much detail as possible, the prospects for siting a deep repository in the municipality of Storuman, and to shed light on the possible positive and negative consequences of such a siting. The feasibility study has led to a discussion within the municipality and the region concerning the siting of a deep repository. In SKB`s opinion, this gives all those concerned ample opportunity to become acquainted with the issues and to assert their interests and present their viewpoints at an early stage. 55 refs.

Technical feasibility study on polycarbonate solar panels

NARCIS (Netherlands)

Hackmann, M.M.; Meuwissen, M.H.H.; Bots, T.L.; Buijs, J.A.H.M.; Broek, K.M.; Kinderman, R.; Tanck, O.B.F.; Schuurmans, F.M.

2004-01-01

This paper describes a technical feasibility study on the application of polycarbonate (PC) plates in a superstrate photovoltaic module design. The lamination process was performed in a conventional laminator apparatus using low temperature curing (100°C) ethylene-vinyl-acetate (EVA) as the potting

Feasibility, Efficacy and Cost Analysis of Promoting Smoking Cessation at Outdoor Smoking "hotspots": a Pre-post Study.

Science.gov (United States)

Cheung, Yee Tak Derek; Lam, Tai Hing; Li, William Ho Cheung; Wang, Man Ping; Chan, Sophia Siu Chee

2017-06-24

To motivate smokers to quit, there is a need for enhanced smoking cessation (SC) recruitment and for innovative and proactive approaches to SC. This study evaluated the feasibility, efficacy and cost of promoting SC in public outdoor areas where smokers gather to smoke (smoking hotspots). We selected 14 smoking hotspots in Hong Kong for SC promotion in 2015. University students were trained as SC ambassadors to deliver brief SC intervention, and to recruit smokers for telephone follow-up. The proportion of smokers accepting the intervention components was recorded. Self-reported abstinence in the past 7 days and knowledge of smoking and health were assessed at the 6-month follow-up. The average costs of each smoker receiving our intervention and quitting were also compared. Of 3,080 smokers approached, 1,278 (41.5%) accepted the souvenir and 920 (29.9%) received brief advice. Of the 210 (6.8%) who consented to the follow-up, 24.5% were aged 15-29 and 46.4% were aged 30-49. Of the 151 smokers successfully contacted within 1 month after recruitment, 16 (10.6%; 1.3% of the 1,278 who received any form of intervention) reported abstinence, and their overall knowledge improved. The average costs for a smoker to receive brief advice, consent to follow-up by telephone, attempt to quit and quit successfully at the 6-month follow-up were US$30, US$132, US$601 and US$1,626, respectively. Promoting SC at smoking hotspots could be a feasible way to achieve satisfactory quitting outcomes at low cost and is useful in the absence of the strengthening of tobacco policies. Our study indicates that outdoor smoking hotspots are feasible platforms for promoting smoking cessation and recruiting smokers for cessation services; satisfactory outcomes can be achieved at a reasonable cost. Our promotion was particularly useful for recruiting young smokers and those who want to quit. It is feasible and efficacious to raise smokers' awareness of smoking cessation when other tobacco control

Feasibility of introducing ferromagnetic materials to onboard bulk high-T{sub c} superconductors to enhance the performance of present maglev systems

Energy Technology Data Exchange (ETDEWEB)

Deng, Zigang, E-mail: zgdeng@gmail.com [Applied Superconductivity Laboratory (ASCLab), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China); State Key Laboratory of Traction Power (TPL), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China); Wang, Jiasu [Applied Superconductivity Laboratory (ASCLab), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China); Zheng, Jun; Zhang, Ya [Applied Superconductivity Laboratory (ASCLab), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China); State Key Laboratory of Traction Power (TPL), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China); Wang, Suyu [Applied Superconductivity Laboratory (ASCLab), Southwest Jiaotong University (SWJTU), Chengdu, Sichuan 610031 (China)

2013-02-14

Highlights: ► Ferromagnetic materials guide the flux distribution of the PMG to bulk positions. ► With ferromagnetic materials, guidance performance can be enhanced greatly. ► A new HTS Maglev system with onboard ferromagnetic materials is designed. ► The design can meet large guidance force requirements for practical applications. -- Abstract: Performance improvement is a long-term research task for the promotion of practical application of promising high-temperature superconducting (HTS) magnetic levitation (maglev) vehicle technologies. We studied the feasibility to enhance the performance of present HTS Maglev systems by introducing ferromagnetic materials to onboard bulk superconductors. The principle here is to make use of the high magnetic permeability of ferromagnetic materials to alter the flux distribution of the permanent magnet guideway for the enhancement of magnetic field density at the position of the bulk superconductors. Ferromagnetic iron plates were added to the upper surface of bulk superconductors and their geometric and positioning effects on the maglev performance were investigated experimentally. Results show that the guidance performance (stability) was enhanced greatly for a particular setup when compared to the present maglev system which is helpful in the application where large guidance forces are needed such as maglev tracks with high degrees of curves.

Feasibility study of CANDU-9 fuel handling system

Energy Technology Data Exchange (ETDEWEB)

Hwang, Jeong Ki; Jo, C. H.; Kim, H. M.

1996-12-01

CANDU`s combination of natural uranium, heavy water and on-power refuelling is unique in its design and remarkable for reliable power production. In order to offer more output, better site utilization, shorter construction time, improved station layout, safety enhancements and better control panel layout, CANDU-9 is now under development with design improvement added to all proven CANDU advantages or applicable technologies. One of its major improvement has been applied to fuel handling system. This system is very similar to that of CANDU-3, and some parts of the system are applied to those of the existing CANDU-6 or CANDU-9. Design concepts and design requirements of fuel handling system for CANDU-9 have been identified to compare with those of the existing CANDU and the design feasibilities have been evaluated. (author). 4 tabs., 13 figs., 9 refs.

Feasibility study: Assess the feasibility of siting a monitored retrievable storage facility

International Nuclear Information System (INIS)

King, J.W.

1993-01-01

The purpose of phase one of this study are: To understand the waste management system and a monitored retrievable storage facility; and to determine whether the applicant has real interest in pursuing the feasibility assessment process. Contents of this report are: Generating electric power; facts about exposure to radiation; handling storage, and transportation techniques; description of a proposed monitored retrievable storage facility; and benefits to be received by host jurisdiction

Feasibility Study for a Hopi Utility-Scale Wind Project

Energy Technology Data Exchange (ETDEWEB)

Kendrick Lomayestewa

2011-05-31

The goal of this project was to investigate the feasibility for the generation of energy from wind and to parallel this work with the development of a tribal utility organization capable of undertaking potential joint ventures in utility businesses and projects on the Hopi reservation. The goal of this project was to investigate the feasibility for the generation of energy from wind and to parallel this work with the development of a tribal utility organization capable of undertaking potential joint ventures in utility businesses and projects on the Hopi reservation. Wind resource assessments were conducted at two study sites on Hopi fee simple lands located south of the city of Winslow. Reports from the study were recently completed and have not been compared to any existing historical wind data nor have they been processed under any wind assessment models to determine the output performance and the project economics of turbines at the wind study sites. Ongoing analysis of the wind data and project modeling will determine the feasibility of a tribal utility-scale wind energy generation.

INTEC High-Level Waste Studies Universal Solvent Extraction Feasibility Study

International Nuclear Information System (INIS)

Banaee, J.; Barnes, C.M.; Battisti, T.; Herrmann, S.; Losinski, S.J.; McBride, S.

2000-01-01

This report summarizes a feasibility study that has been conducted on the Universal Solvent Extraction (UNEX) Process for treatment and disposal of 4.3 million liters of INEEL sodium-bearing waste located at the Idaho Nuclear Technology and Engineering Center. This feasibility study covers two scenarios of treatment. The first, the UNEX Process, partitions the Cs/Sr from the SBW and creates remote-handled LLW and contact-handled TRU waste forms. Phase one of this study, covered in the 30% review documents, dealt with defining the processes and defining the major unit operations. The second phase of the project, contained in the 60% review, expanded on the application of the UNEX processes and included facility requirements and definitions. Two facility options were investigated for the UNEX process, resulting in a 2 x 2 matrix of process/facility scenarios as follows: Option A, UNEX at Greenfield Facility, Option B, Modified UNEX at Greenfield Facility, Option C, UNEX at NWCF, th is document, covers life-cycle costs for all options presented along with results and conclusions determined from the study

Final Technical Report: Renewable Energy Feasibility Study and Resources Assessment

Energy Technology Data Exchange (ETDEWEB)

Rivero, Mariah [BEC Environmental, Inc., Las Vegas, NV (United States)

2016-02-28

In March 2011, the U.S. Department of Energy (DOE) awarded White Pine County, Nevada, a grant to assess the feasibility of renewable resource-related economic development activities in the area. The grant project included a public outreach and training component and was to include a demonstration project; however, the demonstration project was not completed due to lack of identification of an entity willing to locate a project in White Pine County. White Pine County completed the assessment of renewable resources and a feasibility study on the potential for a renewable energy-focused economic sector within the County. The feasibility study concluded "all resources studied were present and in sufficient quantity and quality to warrant consideration for development" and there were varying degrees of potential economic impact based on the resource type and project size. The feasibility study and its components were to be used as tools to attract potential developers and other business ventures to the local market. White Pine County also marketed the County’s resources to the renewable energy business community in an effort to develop contracts for demonstration projects. The County also worked to develop partnerships with local educational institutions, including the White Pine County School District, conducted outreach and training for the local community.

Accuracy of contrast-enhanced spectral mammography for estimating residual tumor size after neoadjuvant chemotherapy in patients with breast cancer: a feasibility study

Directory of Open Access Journals (Sweden)

Filipe Ramos Barra

Full Text Available Abstract Objective: To assess the feasibility of contrast-enhanced spectral mammography (CESM of the breast for assessing the size of residual tumors after neoadjuvant chemotherapy (NAC. Materials and methods: In breast cancer patients who underwent NAC between 2011 and 2013, we evaluated residual tumor measurements obtained with CESM and full-field digital mammography (FFDM. We determined the concordance between the methods, as well as their level of agreement with the pathology. Three radiologists analyzed eight CESM and FFDM measurements separately, considering the size of the residual tumor at its largest diameter and correlating it with that determined in the pathological analysis. Interobserver agreement was also evaluated. Results: The sensitivity, specificity, positive predictive value, and negative predictive value were higher for CESM than for FFDM (83.33%, 100%, 100%, and 66% vs. 50%, 50%, 50%, and 25%, respectively. The CESM measurements showed a strong, consistent correlation with the pathological findings (correlation coefficient = 0.76-0.92; intraclass correlation coefficient = 0.692-0.886. The correlation between the FFDM measurements and the pathological findings was not statistically significant, with questionable consistency (intraclass correlation coefficient = 0.488-0.598. Agreement with the pathological findings was narrower for CESM measurements than for FFDM measurements. Interobserver agreement was higher for CESM than for FFDM (0.94 vs. 0.88. Conclusion: CESM is a feasible means of evaluating residual tumor size after NAC, showing a good correlation and good agreement with pathological findings. For CESM measurements, the interobserver agreement was excellent.

PV solar system feasibility study

International Nuclear Information System (INIS)

Ashhab, Moh’d Sami S.; Kaylani, Hazem; Abdallah, Abdallah

2013-01-01

Highlights: ► This research studies the feasibility of PV solar systems. ► The aim is to develop the theory and application of a hybrid system. ► Relevant research topics are reviewed and some of them are discussed in details. ► A prototype of the PV solar system is designed and built. - Abstract: This research studies the feasibility of PV solar systems and aims at developing the theory and application of a hybrid system that utilizes PV solar system and another supporting source of energy to provide affordable heating and air conditioning. Relevant research topics are reviewed and some of them are discussed in details. Solar heating and air conditioning research and technology exist in many developed countries. To date, the used solar energy has been proved to be inefficient. Solar energy is an abundant source of energy in Jordan and the Middle East; with increasing prices of oil this source is becoming more attractive alternative. A good candidate for the other system is absorption. The overall system is designed such that it utilizes solar energy as a main source. When the solar energy becomes insufficient, electricity or diesel source kicks in. A prototype of the PV solar system that operates an air conditioning unit is built and proper measurements are collected through a data logging system. The measured data are plotted and discussed, and conclusions regarding the system performance are extracted.

PUEBLO OF ZIA RENEWABLE ENERGY DEVELOPMENT FEASIBILITY STUDY

Energy Technology Data Exchange (ETDEWEB)

Pino, Peter M. [Tribal Administrator (Ret.), Pueblo of Zia; Lakshman, Jai [Project Manager (NDA) for Pueblo of Zia; Toole, G. Loren [Principal Investigator, Los Alamos National Laboratory - Energy Analysis Team/ CCS-3, D-4; Hand, Dan [P.E., Sustainable Enginerring; Witcher, James; Emerson, Michael A. [Senior V.P., ARES Corporation; Turner, Jeremy [Executive Director, NM Renewable Energy Transmission Authority; Sandidge, Wendy [Director of Operations, NM Community Capital

2014-06-30

The Pueblo of Zia will conduct a comprehensive feasibility study for best-use application(s) for development of renewable energy resources on its tribally held TRUST lands (i.e., Trust Lands of Zia Indian Reservation). The feasibility study is essential for determining the technical and economic viability of a future renewable project(s) on Zia tribal lands, including the potential economic and environmental benefits for the Tribe. Project Objectives: The feasibility study is essential for determining the technical and economic viability of future renewable project(s) on Zia tribal lands, including the potential economic and environmental benefits for the Tribe to: 1. Provide a balanced local renewable power supply for Zia Pueblo, its members, tribal offices, schools and buildings, and businesses on tribal lands 2. Provide a firm power supply for export and commercial market distribution 3. Provide economic development for the Tribe and its members, including job training and creation, each in accordance with the goals and objectives as conveyed by the Pueblo of Zia Tribal Council, Tribal Administration, and outlined in The Pueblo of Zia Comprehensive Plan and Pueblo of Zia — Zia Enterprise Zone Master Plan. A key goal of the study is to analyze the integrated development of solar, geothermal, and wind renewable energy resources at Zia Pueblo, with added potential to combine gas-fired generation to accomplish energy firming. Geothermal offers a base load source of energy, providing power continuously for end users. Wind and solar offer intermediate and peaking sources of energy, which can be harvested throughout the day, with periods of variable but predicable output. Variability will be managed in an integrated manner, using Zia Pueblo's combined renewable resources to generate high-quality power. Tasks are intended to collect, catalog, map, and analyze existing data on Zia Pueblo's renewable energy resource base and then match resource attributes with

Promoting student case creation to enhance instruction of clinical reasoning skills: a pilot feasibility study

Directory of Open Access Journals (Sweden)

Chandrasekar H

2018-04-01

Full Text Available Hamsika Chandrasekar,1 Neil Gesundheit,2 Andrew B Nevins,3 Peter Pompei,4 Janine Bruce,5 Sylvia Bereknyei Merrell6 1Department of Pediatrics, Boston Children’s Hospital, Boston, MA, USA; 2Department of Medicine, Division of Endocrinology, Stanford University School of Medicine, Stanford, CA, USA; 3Department of Medicine, Division of Infectious Diseases, Stanford University School of Medicine, Stanford, CA, USA; 4Department of Medicine, Division of Primary Care and Population Health, Stanford University School of Medicine, Stanford, CA, USA; 5Department of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA; 6Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA Background: It is a common educational practice for medical students to engage in case-based learning (CBL exercises by working through clinical cases that have been developed by faculty. While such faculty-developed exercises have educational strengths, there are at least two major drawbacks to learning by this method: the number and diversity of cases is often limited; and students decrease their engagement with CBL cases as they grow accustomed to the teaching method. We sought to explore whether student case creation can address both of these limitations. We also compared student case creation to traditional clinical reasoning sessions in regard to tutorial group effectiveness, perceived gains in clinical reasoning, and quality of student–faculty interaction. Methods: Ten first-year medical students participated in a feasibility study wherein they worked in small groups to develop their own patient case around a preassigned diagnosis. Faculty provided feedback on case quality afterwards. Students completed pre- and post-self-assessment surveys. Students and faculty also participated in separate focus groups to compare their case creation experience to traditional CBL sessions. Results: Students reported high levels of team engagement

Feasibility study on volcanic power generation system

Energy Technology Data Exchange (ETDEWEB)

None

1977-07-01

Investigations were carried out to determine the feasibility of volcanic power generation on Satsuma Io Island. Earthquakes were studied, as were the eruptions of subaerial and submarine hot springs. Hydrothermal rock alteration was studied and electrical surveys were made. General geophysical surveying was performed with thermocameras and radiation monitoring equipment. In particular, the Toyoba mine was studied, both with respect to its hot spring and its subsurface temperatures.

IPNS upgrade: A feasibility study

International Nuclear Information System (INIS)

1995-04-01

Many of Argonne National Laboratory's (ANL's) scientific staff members were very active in R ampersand D work related to accelerator-based spoliation sources in the 1970s and early 1980s. In 1984, the Seitz/Eastman Panel of the National Academy of Sciences reviewed U.S. materials science research facilities. One of the recommendations of this panel was that the United States build a reactor-based steady-state source, the Advanced Neutron Source (ANS), at Oak Ridge National Laboratory. Subsequently, R ampersand D activities related to the design of an accelerator-based source assumed a lower priority. The resumption of pulsed-source studies in this country started simultaneously with design activities in Europe aimed at the European Spallation Source (ESS). The European Community funded a workshop in September 1991 to define the parameters of the ESS. Participants in this workshop included both accelerator builders and neutron source users. A consortium of European countries has proposed to build a 5-MW pulsed source, and a feasibility study is currently under way. Soon after the birth of the ESS, a small group at ANL set about bringing themselves up to date on pulsed-source information since 1984 and studied the feasibility of upgrading ANL's Intense Pulsed Neutron Source (IPNS) to 1 MW by means of a rapidly cycling synchrotron that could be housed, along with its support facilities, in existing buildings. In early 1993, the Kohn panel recommended that (1) design and construction of the ANS should be completed according to the proposed project schedule and (2) development of competitive proposals for cost-effective design and construction of a 1-MW pulsed spallation source should be authorized immediately

IPNS upgrade: A feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-04-01

Many of Argonne National Laboratory`s (ANL`s) scientific staff members were very active in R&D work related to accelerator-based spoliation sources in the 1970s and early 1980s. In 1984, the Seitz/Eastman Panel of the National Academy of Sciences reviewed U.S. materials science research facilities. One of the recommendations of this panel was that the United States build a reactor-based steady-state source, the Advanced Neutron Source (ANS), at Oak Ridge National Laboratory. Subsequently, R&D activities related to the design of an accelerator-based source assumed a lower priority. The resumption of pulsed-source studies in this country started simultaneously with design activities in Europe aimed at the European Spallation Source (ESS). The European Community funded a workshop in September 1991 to define the parameters of the ESS. Participants in this workshop included both accelerator builders and neutron source users. A consortium of European countries has proposed to build a 5-MW pulsed source, and a feasibility study is currently under way. Soon after the birth of the ESS, a small group at ANL set about bringing themselves up to date on pulsed-source information since 1984 and studied the feasibility of upgrading ANL`s Intense Pulsed Neutron Source (IPNS) to 1 MW by means of a rapidly cycling synchrotron that could be housed, along with its support facilities, in existing buildings. In early 1993, the Kohn panel recommended that (1) design and construction of the ANS should be completed according to the proposed project schedule and (2) development of competitive proposals for cost-effective design and construction of a 1-MW pulsed spallation source should be authorized immediately.

Feasibility Study of a Mobile Health Intervention for Older Adults on Oral Anticoagulation Therapy

Directory of Open Access Journals (Sweden)

Jung-Ah Lee PhD, RN

2016-10-01

Full Text Available Background: Oral anticoagulation treatment (OAT such as warfarin therapy is recommended for older adults with atrial fibrillation, heart failure, or who are at risk for venous thromboembolism. Despite its proven benefits, older adults report both dissatisfaction with OAT and reduced quality of life that can potentially lead to low adherence to OAT and decreased treatment efficacy. Objective: To test the feasibility of Mobile Applications for Seniors to enhance Safe anticoagulation therapy (MASS, a mobile-based health technology intervention designed to promote independence and self-care. Method s: This pilot study used a single-arm experimental pre–post design to test the feasibility of a 3-month intervention using MASS in 18 older adults (male: n = 14; White: n = 9; Hispanic: n = 7; Other: n = 2; M age = 67. MASS was available in English or Spanish. Participants completed surveys about their OAT knowledge, attitudes, quality of life with OAT, and adherence at baseline and at a 3-month follow-up. Satisfaction with the MASS intervention was also assessed at follow-up. Results: Anticoagulation knowledge significantly improved from baseline to follow-up ( M base = 12.5 ± 5.51, M follow-up = 14.78 ± 3.93, p = .007. Other outcomes were not different, pre- and post-tests. Participants reported they were generally satisfied with MASS, its ease of use and its usefulness. Conclusion: The results showed use of MASS improved older adults’ knowledge of OAT. Using mHealth apps may enhance self-care among older adults with chronic conditions who are also taking oral anticoagulants.

Conducting feasibilities in clinical trials: An investment to ensure a good study

Directory of Open Access Journals (Sweden)

Viraj Rajadhyaksha

2010-01-01

Full Text Available Conducting clinical trial feasibility is one of the first steps in clinical trial conduct. This process includes assessing internal and environmental capacity, alignment of the clinical trial in terms of study design, dose of investigational product, comparator, patient type, with the local environment and assessing potential of conducting clinical trial in a specific country. A robust feasibility also ensures a realistic assessment and capability to conduct the clinical trial. For local affiliates of pharmaceutical organizations, and contract research organizations, this is a precursor to study placement and influences the decision of study placement. This article provides details on different types of feasibilities, information which is to be included and relevance of each. The article also aims to provide practical hands-on suggestions to make feasibilities more realistic and informative.

Conducting feasibilities in clinical trials: an investment to ensure a good study.

Science.gov (United States)

Rajadhyaksha, Viraj

2010-07-01

Conducting clinical trial feasibility is one of the first steps in clinical trial conduct. This process includes assessing internal and environmental capacity, alignment of the clinical trial in terms of study design, dose of investigational product, comparator, patient type, with the local environment and assessing potential of conducting clinical trial in a specific country. A robust feasibility also ensures a realistic assessment and capability to conduct the clinical trial. For local affiliates of pharmaceutical organizations, and contract research organizations, this is a precursor to study placement and influences the decision of study placement. This article provides details on different types of feasibilities, information which is to be included and relevance of each. The article also aims to provide practical hands-on suggestions to make feasibilities more realistic and informative.

Cognitive Enhancement Therapy for Adults with Autism Spectrum Disorder: Results of an 18-Month Feasibility Study

Science.gov (United States)

Eack, Shaun M.; Greenwald, Deborah P.; Hogarty, Susan S.; Bahorik, Amber L.; Litschge, Maralee Y.; Mazefsky, Carla A.; Minshew, Nancy J.

2013-01-01

Adults with autism experience significant impairments in social and non-social information processing for which few treatments have been developed. This study conducted an 18-month uncontrolled trial of Cognitive Enhancement Therapy (CET), a comprehensive cognitive rehabilitation intervention, in 14 verbal adults with autism spectrum disorder to…

Feasibility study of CT perfusion imaging for prostate carcinoma

International Nuclear Information System (INIS)

Cullu, Nesat; Kantarci, Mecit; Ogul, Hayri; Pirimoglu, Berhan; Karaca, Leyla; Kizrak, Yesim; Adanur, Senol; Koc, Erdem; Polat, Ozkan; Okur, Aylin

2014-01-01

The aim of this feasibility study was to obtain initial data with which to assess the efficiency of perfusion CT imaging (CTpI) and to compare this with magnetic resonance imaging (MRI) in the diagnosis of prostate carcinoma. This prospective study involved 25 patients with prostate carcinoma undergoing MRI and CTpI. All analyses were performed on T2-weighted images (T2WI), apparent diffusion coefficient (ADC) maps, diffusion-weighted images (DWI) and CTp images. We compared the performance of T2WI combined with DWI and CTp alone. The study was approved by the local ethics committee, and written informed consent was obtained from all patients. Tumours were present in 87 areas according to the histopathological results. The diagnostic performance of the T2WI+DWI+CTpI combination was significantly better than that of T2WI alone for prostate carcinoma (P < 0.001). The diagnostic value of CTpI was similar to that of T2WI+DWI in combination. There were statistically significant differences in the blood flow and permeability surface values between prostate carcinoma and background prostate on CTp images. CTp may be a valuable tool for detecting prostate carcinoma and may be preferred in cases where MRI is contraindicated. If this technique is combined with T2WI and DWI, its diagnostic value is enhanced. (orig.)

Results of FY 2002 of feasibility study on commercialized fast reactor cycle systems. Phase 2

International Nuclear Information System (INIS)

2003-06-01

Japan Nuclear Cycle Development Institute (JNC) and Japan Atomic Power Company (JAPC, that is the representative of the electric utilities in Japan) established a new organization to develop a commercialized fast reactor (FR) cycle system on July 1, 1999 and feasibility study (F/S) was undertaken in order to determine the promising concepts and to define the necessary R and D tasks. During Phase 1 (JFY 1999 and 2000), a number of candidate concepts were screened from various options, featuring innovative technologies. In the F/S, the options were evaluated and conceptual designs were examined considering the attainable perspectives for following: 1) ensuring safety, 2) economic competitiveness to future LWRs, 3) efficient utilization of resources, 4) reduction of environmental burden and 5) enhancement of nuclear non-proliferation. The F/S should also guide the necessary R and D to commercialize FR cycle system. To begin with the study of feasible candidate concepts screened in Phase I, Phase 2 started in the plan for five years in 2001. This aims at clarifying several feasible candidate concepts and deciding the research plan after Phase 3 as taking into consideration the innovative technology. As for this plan, an interim report will be carried out in 2003 as one pause and the prospect to clarify the feasible candidates will be expected. Furthermore, after the completion of this research and investigation program, research and development activities will be carried out under a rolling plan in which reviews will be carried out approximately every five years. The objective of these R and D activities is to make a proposal regarding highly attractive and competitive FR cycle system technology that assures safety by 2015. This report summarizes the results of F/S of Phase 2 in 2002. In 2002, the second year of Phase 2, the study was advanced along with the plan which was evaluated by the committee for the Evaluation. Then, in the study of FR system and fuel cycle

Feasibility study of an active soft catheter actuated by SMA wires

Science.gov (United States)

Konh, Bardia; Karimi, Saeed; Miller, Scott

2018-03-01

This study aims to assess the feasibility of using a combination of thin elastomer tubes and SMA wires to develop an active catheter. Cardiac catheters have been widely used in investigational and interventional procedures such as angiography, angioplasty, electro- physiology, and endocardial ablation. The commercial models manually steer inside the patient's body via internally installed pull wires. Active catheters, on the other hand, have the potential to revolutionize surgical procedures because of their computer-controlled and enhanced motion. Shape memory alloys have been used for almost a decade as a trustworthy actuator for biomedical applications. In this work, SMA wires were attached to a small pressurized elastomer tube to realize deflection. The tube was pressurized to maintain a constant stress on the SMA wires. The tip motion via actuation of SMA wires was then measured and reported. The results of this study showed that by adopting an appropriate training process for the SMA wires prior to performing the experiments and adopting an appropriate internal pressure for the elastomer tube, less external loads on SMA wires would be needed for a consistent actuation.

Front Range Forest Health Partnership Phase 1 feasibility study

Energy Technology Data Exchange (ETDEWEB)

Volkin, P

1998-09-01

The Front Range Forest Health Partnership is an alliance of individuals, citizen groups, federal, state, private, and nonprofit organizations that formed to promote forest health restoration and reduce fire risks on Colorado's Front Range. The partnership promotes selective thinning to restore forest health and supports economically feasible end uses for wood waste materials. The Phase I study was initiated to determine the environmental and economic feasibility of using wood wastes from forested and urban areas for the production of fuel-grade ethanol.

Pre-feasibility study template for nZEB pilot projects development

OpenAIRE

Crespo Sánchez, Eva

2015-01-01

This document corresponds to Task 5.2 NZEB pilot projects development, Deliverable 5.2 Basic project conceptual design with feasibility analysis for eight pilot project of the SUSTAINCO project and should present a structure of pre-feasibility studies for eight NZEB projects implementation. It aims to give an overview of how SUSTAINCO project implementation is to be prepared and which technical and financial parameters to concern.

Important considerations for feasibility studies in physical activity research involving persons with multiple sclerosis: a scoping systematic review and case study.

Science.gov (United States)

Learmonth, Yvonne C; Motl, Robert W

2018-01-01

Much research has been undertaken to establish the important benefits of physical activity in persons with multiple sclerosis (MS). There is disagreement regarding the strength of this research, perhaps because the majority of studies on physical activity and its benefits have not undergone initial and systematic feasibility testing. We aim to address the feasibility processes that have been examined within the context of physical activity interventions in MS. A systematic scoping review was conducted based on a literature search of five databases to identify feasibility processes described in preliminary studies of physical activity in MS. We read and extracted methodology from each study based on the following feasibility metrics: process (e.g. recruitment), resource (e.g. monetary costs), management (e.g. personnel time requirements) and scientific outcomes (e.g. clinical/participant reported outcome measures). We illustrate the use of the four feasibility metrics within a randomised controlled trial of a home-based exercise intervention in persons with MS. Twenty-five studies were identified. Resource feasibility (e.g. time and resources) and scientific outcomes feasibility (e.g. clinical outcomes) methodologies were applied and described in many studies; however, these metrics have not been systematically addressed. Metrics related to process feasibility (e.g. recruitment) and management feasibility (e.g. human and data management) are not well described within the literature. Our case study successfully enabled us to address the four feasibility metrics, and we provide new information on management feasibility (i.e. estimate data completeness and estimate data entry) and scientific outcomes feasibility (i.e. determining data collection materials appropriateness). Our review highlights the existing research and provides a case study which assesses important metrics of study feasibility. This review serves as a clarion call for feasibility trials that will

Dual-Doppler Feasibility Study

Science.gov (United States)

Huddleston, Lisa L.

2012-01-01

When two or more Doppler weather radar systems are monitoring the same region, the Doppler velocities can be combined to form a three-dimensional (3-D) wind vector field thus providing for a more intuitive analysis of the wind field. A real-time display of the 3-D winds can assist forecasters in predicting the onset of convection and severe weather. The data can also be used to initialize local numerical weather prediction models. Two operational Doppler Radar systems are in the vicinity of Kennedy Space Center (KSC) and Cape Canaveral Air Force Station (CCAFS); these systems are operated by the 45th Space Wing (45 SW) and the National Weather Service Melbourne, Fla. (NWS MLB). Dual-Doppler applications were considered by the 45 SW in choosing the site for the new radar. Accordingly, the 45th Weather Squadron (45 WS), NWS MLB and the National Aeronautics and Space Administration tasked the Applied Meteorology Unit (AMU) to investigate the feasibility of establishing dual-Doppler capability using the two existing systems. This study investigated technical, hardware, and software requirements necessary to enable the establishment of a dual-Doppler capability. Review of the available literature pertaining to the dual-Doppler technique and consultation with experts revealed that the physical locations and resulting beam crossing angles of the 45 SW and NWS MLB radars make them ideally suited for a dual-Doppler capability. The dual-Doppler equations were derived to facilitate complete understanding of dual-Doppler synthesis; to determine the technical information requirements; and to determine the components of wind velocity from the equation of continuity and radial velocity data collected by the two Doppler radars. Analysis confirmed the suitability of the existing systems to provide the desired capability. In addition, it is possible that both 45 SW radar data and Terminal Doppler Weather Radar data from Orlando International Airport could be used to alleviate any

Active Treatment for Idiopathic Adolescent Scoliosis (ACTIvATeS): a feasibility study.

Science.gov (United States)

Williams, Mark A; Heine, Peter J; Williamson, Esther M; Toye, Francine; Dritsaki, Melina; Petrou, Stavros; Crossman, Richard; Lall, Ranjit; Barker, Karen L; Fairbank, Jeremy; Harding, Ian; Gardner, Adrian; Slowther, Anne-Marie; Coulson, Neil; Lamb, Sarah E

2015-07-01

The feasibility of conducting a definitive randomised controlled trial (RCT) evaluating the clinical effectiveness and cost-effectiveness of scoliosis-specific exercises (SSEs) for adolescent idiopathic scoliosis (AIS) is uncertain. The aim of this study was to assess the feasibility of conducting a large, multicentre trial of SSE treatment for patients with AIS, in comparison with standard care, and to refine elements of the study design. The objectives were to (1) update a systematic review of controlled trials evaluating the efficacy of SSE in AIS; (2) survey UK orthopaedic surgeons and physiotherapists to determine current practice, patient populations and equipoise; (3) randomise 50 adolescents to a feasibility trial of either usual care or SSE interventions across a range of sites; (4) develop, document and assess acceptability and adherence of interventions; (5) assess and describe training requirements of physiotherapists; and (6) gain user input in all relevant stages of treatment and protocol design. Multicomponent feasibility study including UK clinician survey, systematic literature review and a randomised feasibility trial. The randomised feasibility study involved four secondary care NHS trusts providing specialist care for patients with AIS. The randomised feasibility study recruited people aged 10-16 years with mild AIS (Cobb angle of physiotherapy SSE programme supported by a home exercise plan. Our choice of intervention was informed by a systematic review of exercise interventions for AIS. The main outcome was feasibility of recruitment to the randomised study. Other elements were to inform choice of outcomes for a definitive trial and included curve severity, quality of life, requirement for surgery/brace, adverse events, psychological symptoms, costs and health utilities. A UK survey of orthopaedic consultants and physiotherapists indicated a wide variation in current provision of exercise therapy through physiotherapy services. It also found

Study of proximal femoral bone perfusion with 3D T1 dynamic contrast-enhanced MRI: a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Budzik, Jean-Francois [Groupe Hospitalier de l' Institut Catholique de Lille / Faculte Libre de Medecine, Service d' Imagerie Medicale, Lille (France); Centre de Consultation et d' Imagerie de l' Appareil Locomoteur, CHRU de Lille, Service de Radiologie et Imagerie Musculosquelettique, Lille (France); Universite Catholique de Lille, Lille (France); Universite Nord de France, Lille (France); EA 4490 PMOI (Physiopathologie des Maladies Osseuses Inflammatoires) IFR 114 PRES Universite Lille Nord de France, Lille (France); Lefebvre, Guillaume; El Rafei, Mazen [Centre de Consultation et d' Imagerie de l' Appareil Locomoteur, CHRU de Lille, Service de Radiologie et Imagerie Musculosquelettique, Lille (France); Universite Nord de France, Lille (France); CHU Lille, Lille (France); Forzy, Gerard [Universite Catholique de Lille, Lille (France); Universite Nord de France, Lille (France); Groupe Hospitalier de l' Institut Catholique de Lille, Laboratoire de Biologie, Departement de Biostatistiques, Lille (France); Chechin, David [Philips Medical Systems, Suresnes (France); Cotten, Anne [Centre de Consultation et d' Imagerie de l' Appareil Locomoteur, CHRU de Lille, Service de Radiologie et Imagerie Musculosquelettique, Lille (France); Universite Nord de France, Lille (France); EA 4490 PMOI (Physiopathologie des Maladies Osseuses Inflammatoires) IFR 114 PRES Universite Lille Nord de France, Lille (France); CHU Lille, Lille (France)

2014-12-15

The objective of this study was to compare measurements of semi-quantitative and pharmacokinetic parameters in areas of red (RBM) and yellow bone marrow (YBM) of the hip, using an in-house high-resolution DCE T1 sequence, and to assess intra- and inter-observer reproducibility of these measurements. The right hips of 21 adult patients under 50 years of age were studied. Spatial resolution was 1.8 x 1.8 x 1.8 mm{sup 3}, and temporal resolution was 13.5 seconds. Two musculoskeletal radiologists independently processed DCE images and measured semi-quantitative and pharmacokinetic parameters in areas of YBM and RBM. Signal-to-noise (SNR) and contrast-to-noise (CNR) ratios were calculated. Intra- and inter-observer reproducibility was assessed. Area under the curve (AUC) and initial slope (IS) were significantly greater for RBM than for YBM (p < 0.05). K{sup trans} and k{sub ep} were also significantly greater for RBM (p < 0.05). There was no significant difference in time to peak between the regions (p < 0.05). SNR, CNR, and intra- and inter-observer reproducibility were all good. DCE study of the whole hip is feasible with high spatial resolution using a 3D T1 sequence. Measures were possible even in low vascularized areas of the femoral head. K{sup trans}, k{sub ep}, AUC, and IS values were significantly different between red and yellow marrow, whereas TTP values were not. (orig.)

Bond Feasibility Study. Project Identification Committee Report.

Science.gov (United States)

Wichita Public Schools, KS.

A committee, appointed by the Board of Education, was requested to make a comprehensive study of the school building needs of Unified School District No. 259. In an attempt to determine the feasibility of a general bond election to upgrade the public schools, the specific charge to the committee was to evaluate the needs for physical plant…

Ear-EEG from generic earpieces: A feasibility study

DEFF Research Database (Denmark)

Kidmose, Preben; Looney, D; Jochumsen, Lars

2013-01-01

key patient needs (discreet, unobstrusive, user-friendly, robust) and that is low-cost and suitable for off-the-shelf use; thus promising great advantages for healthcare applications. Its feasibility is validated in a comprehensive comparative study with our established prototype, based...

Fast-mixed spectrum reactor interim report initial feasibility study

International Nuclear Information System (INIS)

Fischer, G.J.; Cerbone, R.J.

1979-01-01

The report summarizes the results of an initial four-month feasibility study of the Fast-Mixed Spectrum Reactor (FMSR). Reactor physics, fuel cycle, and thermal-hydraulic analyses were performed on a reference design. These results when coupled to a fuel and materials evaluation performed in cooperation with the Argonne National Laboratory indicate that the FMSR is feasible provided the fuels, cladding, and subassembly ducts can survive a peak fuel burnup of 15 to 20 atom percent heavy metal and peak fluences of 8 x 10 23 (nvt > 0.1 MeV). The results of this short study have also provided a basis for exploring alternative designs requiring significantly lower peak burnup and fluences for their operation

Longitudinal study of the feasibility of using ecological momentary assessment to study teacher stress: Objective and self-reported measures.

Science.gov (United States)

McIntyre, Teresa M; McIntyre, Scott E; Barr, Christopher D; Woodward, Phillip S; Francis, David J; Durand, Angelia C; Mehta, Paras; Kamarck, Thomas W

2016-10-01

There is a lack of comprehensive research on Ecological Momentary Assessment (EMA) feasibility to study occupational stress, especially its long-term sustainability. EMA application in education contexts has also been sparse. This study investigated the feasibility of using EMA to study teacher stress over 2 years using both objective compliance data and a self-reported feasibility survey. It also examined the influence of individual and school factors on EMA feasibility. Participants were 202 sixth through eighth grade teachers from 22 urban middle schools in the southern United States. EMA was implemented via an iPod-based Teacher Stress Diary (TSD). Teachers recorded demands, stress responses, and resources during 12 days (6 waves) over 2 years. Feasibility was assessed via compliance data generated by the TSD (e.g., entry completion) and an EMA Feasibility Survey of self-reported user-friendliness and EMA interference. The results showed high compliance regarding entry and item completion, and completion time, which was sustained over time. User-friendliness was appraised as very high and EMA interference as low. Initial difficulties regarding timing and length of assessments were addressed via EMA method refinement, resulting in improved feasibility. Teachers' ethnicity, age, marital status, grade/course taught, class size, class load, and daily workload impacted feasibility. The results supported the feasibility of using EMA to study work stress longitudinally and the value of continued feasibility monitoring. They also support EMA use to study teacher stress and inform EMA implementation in schools. Some teacher and school factors need to be taken into consideration when deciding on EMA implementation in education contexts. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Enhancing condom use experiences among young men to improve correct and consistent condom use: feasibility of a home-based intervention strategy (HIS-UK).

Science.gov (United States)

Stone, Nicole; Graham, Cynthia; Anstee, Sydney; Brown, Katherine; Newby, Katie; Ingham, Roger

2018-01-01

Condoms remain the main protection against sexually transmitted infections (STIs) when used correctly and consistently. Yet, there are many reported barriers to their use such as negative attitudes, reduced sexual pleasure, fit-and-feel problems and erection difficulties. The UK home-based intervention strategy (HIS-UK) is a behaviour change condom promotion intervention for use among young men (aged 16-25 years) designed to increase condom use by enhancing enjoyment of condom-protected intercourse. The objective of this feasibility study was to test HIS-UK for viability, operability and acceptability. Along with an assessment of the recruitment strategy and adherence to the intervention protocol, the study tested the reliability and suitability of a series of behavioural and condom use outcome measures to assess condom use attitudes, motivations, self-efficacy, use experience, errors and problems and fit and feel. The HIS-UK intervention and associated assessment instruments were tested for feasibility using a single-arm, repeated measures design with baseline measurement and two follow-up measurements over 3 months. A 3-month target of 50 young men completing the baseline questionnaire was set. Twenty process and acceptability evaluation interviews with participants and health promotion professionals were conducted post trial. Of the 61 young men who registered for the study, 57 completed the baseline questionnaire and 33 met with the study researcher to receive the HIS-UK condom kit. Twenty-one young men remained for the duration of the study (64% retention). The Cronbach's alpha scores for the condom use outcome measures were 0.84 attitudes, 0.78 self-efficacy, 0.83 use experience, 0.69 errors and problems and 0.75 fit and feel. Participant and health professional feedback indicated strong acceptability of the intervention. The feasibility study demonstrated that our recruitment strategy was appropriate and the target sample size was achieved. Adherence was

Feasibility of Jujube peeling using novel infrared radiation heating technology

Science.gov (United States)

Infrared (IR) radiation heating has a promising potential to be used as a sustainable and effective method to eliminate the use of water and chemicals in the jujube-peeling process and enhance the quality of peeled products. The objective of this study was to investigate the feasibility of use IR he...

Feasibility study on intersection in North Sumatera

Science.gov (United States)

Hastuty, I. P.; Sembiring, I. S.; Anas, R.; Lubis, A. S.

2018-02-01

Traffic congestion is one of the problems faced by big cities, One of them is Binjai city and Medan city in North Sumatera. One of the causes of congestion is intersection of roads with highway and roads with railroads. To ensure the smooth movement of vehicles, technical handling at the intersection is needed. Therefore, it is necessary to pre-study the feasibility of level crossing in Binjai and Medan to be able to assess the investment needs and the level of importance of road development in the region. The development of transportation infrastructure and facilities is based on the thought of improving the transportation network system. The necessity of systemical integrated transportation system handling is needed in creating a transportation efficiency. The purpose of this study is to identify and prioritize the needs of the railway crossings. The objective which we want to be achieved is to obtain a document that contains technical, economic and environmental ability indicators as a reference in the feasibility and planning studies. The methodology used is collecting the primary data, secondary data, introduction of study area as the initial analysis of the problem. From the study it can be concluded that the existence of railway interchange will move the movement through traffic so it will not interfere the movement of traffic within urban areas and it keeps the national road network performance is still good.

International Case-Control Study of Adult Brain, Head and Neck Tumours: Results of the Feasibility Study (invited paper)

International Nuclear Information System (INIS)

Cardis, E.; Kilkenny, M.

1999-01-01

The objectives of the feasibility study were to collect and analyse the information necessary to assess the feasibility of a multi-centric study of adult head and neck tumours (including brain tumours) and mobile telephones. Information was obtained on the availability and accessibility of records from companies, the prevalence of mobile telephone use over time and the expected number of tumour cases in the proposed study regions. The conclusion is that it is feasible to develop a study of the relation between mobile telephone use and brain cancer risk. The feasibility of a study of the relation between radiofrequency exposure and cancer risk is, however, unclear at present. It is unknown whether a sufficiently accurate and precise RF exposure gradient can be derived to classify adequately each subject in the proposed study. A study of the relation between mobile telephone use and risk of salivary gland tumours and acoustic neurinomas is probably feasible, but more information is required about the logistic difficulties of ascertaining these cases in the study regions. Two subcommittees have been formed to develop the exposure measurement and epidemiological aspect of the study. (author)

Impact of a family medicine resident wellness curriculum: a feasibility study.

Science.gov (United States)

Runyan, Christine; Savageau, Judith A; Potts, Stacy; Weinreb, Linda

2016-01-01

Up to 60% of practicing physicians report symptoms of burnout, which often peak during residency. Residency is also a relevant time for habits of self-care and resiliency to be emphasized. A growing literature underscores the importance of this; however, evidence about effective burnout prevention curriculum during residency remains limited. The purpose of this project is to evaluate the impact of a new, 1-month wellness curriculum for 12 second-year family medicine residents on burnout, empathy, stress, and self-compassion. The pilot program, introduced during a new rotation emphasizing competencies around leadership, focused on teaching skills to cultivate mindfulness and self-compassion in order to enhance empathy and reduce stress. Pre-assessments and 3-month follow-up assessments on measures of burnout, empathy, self-compassion, and perceived stress were collected to evaluate the impact of the curriculum. It was hypothesized that this curriculum would enhance empathy and self-compassion as well as reduce stress and burnout among family medicine residents. Descriptive statistics revealed positive trends on the mean scores of all the measures, particularly the Mindfulness Scale of the Self-Compassion Inventory and the Jefferson Empathy Scale. However, the small sample size and lack of sufficient power to detect meaningful differences limited the use of inferential statistics. This feasibility study demonstrates how a residency wellness curriculum can be developed, implemented, and evaluated with promising results, including high participant satisfaction.

DPC loading feasibility study report

International Nuclear Information System (INIS)

Dafoe, R.E.; Lopez, D.A.; Williams, K.L.

1997-11-01

Disposal of radioactive wastes now stored at the Idaho Chemical Processing Plant at the Idaho National Engineering and Environmental Laboratory is mandated under a ''Settlement Agreement'' between the Department of Energy and the State of Idaho. This study investigates the feasibility of using the Dry Transfer Cell facility to package waste into Dual Purpose Canisters for interim storage at the adjacent Dry Storage System comprised of an interim storage pad with NUHOMS reg-sign storage modules. The wastes would then be road-ready for eventual disposal in a permanent repository. The operating period for these activities is expected to be from 2015 to 2035

Training Endogenous Task Shifting Using Music Therapy: A Feasibility Study.

Science.gov (United States)

Lynch, Colleen; LaGasse, A Blythe

2016-01-01

People with acquired brain injury (ABI) are highly susceptible to disturbances in executive functioning (EF), and these effects are pervasive. Research studies using music therapy for cognitive improvement in this population are limited. The purpose of this study was to determine the feasibility of a Musical Executive Function Training (MEFT) intervention to address task-shifting skills in adults with ABI and to obtain preliminary evidence of intervention effect on task shifting. Fourteen participants were randomly assigned to one of three groups: a music therapy intervention group (MTG), a singing group (SG), or the no-intervention control group (CG). The SG and MTG met for one hour a day for five days. Feasibility measures included participant completion rates and intervention fidelity. Potential benefits were measured using the Trail Making Test and the Paced Auditory Serial Addition Task as a pre- and posttest measure. Participant completion rates and interventionist fidelity to the protocol supported feasibility. One-way ANOVA of the pre- and posttest group differences revealed a trend toward improvement in the MTG over the SG. Feasibility and effect size data support a larger trial of the MEFT protocol. © the American Music Therapy Association 2016. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Final Progress Report: Isotope Identification Algorithm for Rapid and Accurate Determination of Radioisotopes Feasibility Study

International Nuclear Information System (INIS)

Rawool-Sullivan, Mohini; Bounds, John Alan; Brumby, Steven P.; Prasad, Lakshman; Sullivan, John P.

2012-01-01

This is the final report of the project titled, 'Isotope Identification Algorithm for Rapid and Accurate Determination of Radioisotopes,' PMIS project number LA10-HUMANID-PD03. The goal of the work was to demonstrate principles of emulating a human analysis approach towards the data collected using radiation isotope identification devices (RIIDs). It summarizes work performed over the FY10 time period. The goal of the work was to demonstrate principles of emulating a human analysis approach towards the data collected using radiation isotope identification devices (RIIDs). Human analysts begin analyzing a spectrum based on features in the spectrum - lines and shapes that are present in a given spectrum. The proposed work was to carry out a feasibility study that will pick out all gamma ray peaks and other features such as Compton edges, bremsstrahlung, presence/absence of shielding and presence of neutrons and escape peaks. Ultimately success of this feasibility study will allow us to collectively explain identified features and form a realistic scenario that produced a given spectrum in the future. We wanted to develop and demonstrate machine learning algorithms that will qualitatively enhance the automated identification capabilities of portable radiological sensors that are currently being used in the field.

The feasibility study on commercialized fast reactor cycle system

International Nuclear Information System (INIS)

Noda, Hiroshi

2002-01-01

The feasibility study on commercialized Fast Reactor cycle system (FS) has been carried out by a joint team with the participation of all parties concerned in Japan since July, 1999. It aims to clarify various perspectives for commercialized fast reactor cycle system and also suggest development strategies to diverse social needs in the 21 st century. The FS consists of several phases. The phase 1 has progressed as planned and the highly feasible candidate concepts with innovative technologies have been screened out among a wide variety of concepts. During the phase 2, approximately five years after the phase 1, the in-depth design studies and engineering scale tests of key technologies are being conducted to verify and validate the feasibility of screened candidate concepts. At the end of the phase 2, a few promising concepts will be selected with their R and D tasks. The paper describes the results of the phase 1, the activities of the phase 2 and the new concept related to the fast reactor fuel cycle focusing on the reduction in environmental burden, which is one of key factors to sustain the nuclear power generation in the 21 st century

A feasibility study of thyroid cancer among patients treated with I-131

International Nuclear Information System (INIS)

Anderson, T.W.

1984-04-01

This study examined the feasibility of conducting a Canada-wide follow-up study of persons receiving I-131 before 1970, to see if current estimates of induction of thyroid cancer are well founded. It is concluded that such a study is not feasible due to the widespread destruction of old records, and the limited quantity of personal identifying information on those records that do still exist

Feasibility study for private-sector treatment services for alpha-contaminated low-level mixed wastes

International Nuclear Information System (INIS)

Bloom, R.R.; Rodriguez, R.R.

1995-01-01

Rust Federal Services, under contract to the United States Department of Energy (DOE), Idaho Operations Office, performed a study to develop and evaluate the feasibility of a suggested private sector solution for the treatment of alpha-contaminated low-level mixed waste (ALLMW) stored or produced at the Idaho National Engineering Laboratory (INEL). The feasibility study is an initial step in the potential procurement of privatized treatment services for these wastes. Rust's derived objective of the feasibility study was to define an optimal treatment system and analyze the feasibility of that system for accomplishing the processing objectives specified by DOE. All aspects of the selected treatment system were addressed in the feasibility study, including technical, regulatory, public involvement, and financial considerations. Two central elements of the study were a technology screening task to select the optimal treatment system and an analysis of the institutional, business, financial, and contractual issues that are likely to accompany the privatization of treatment services for DOE

Deschutes estuary feasibility study: hydrodynamics and sediment transport modeling

Science.gov (United States)

George, Douglas A.; Gelfenbaum, Guy; Lesser, Giles; Stevens, Andrew W.

2006-01-01

Continual sediment accumulation in Capitol Lake since the damming of the Deschutes River in 1951 has altered the initial morphology of the basin. As part of the Deschutes River Estuary Feasibility Study (DEFS), the United States Geological Survey (USGS) was tasked to model how tidal and storm processes will influence the river, lake and lower Budd Inlet should estuary restoration occur. Understanding these mechanisms will assist in developing a scientifically sound assessment on the feasibility of restoring the estuary. The goals of the DEFS are as follows. - Increase understanding of the estuary alternative to the same level as managing the lake environment.

A feasibility study of unconventional planar ligand spacers in chalcogenide nanocrystals.

Science.gov (United States)

Lukose, Binit; Clancy, Paulette

2016-05-18

The solar cell efficiency of chalcogenide nanocrystals (quantum dots) has been limited in the past by the insulation between neighboring quantum dots caused by intervening, often long-chain, aliphatic ligands. We have conducted a computationally based feasibility study to investigate the use of ultra-thin, planar, charge-conducting ligands as an alternative to traditional long passive ligands. Not only might these radically unconventional ligands decrease the mean distance between adjacent quantum dots, but, since they are charge-conducting, they have the potential to actively enhance charge migration. Our ab initio studies compare the binding energies, electronic energy gaps, and absorption characteristics for both conventional and unconventional ligands, such as phthalocyanines, porphyrins and coronene. This comparison identified these unconventional ligands with the exception of titanyl phthalocyanine, that bind to themselves more strongly than to the surface of the quantum dot, which is likely to be less desirable for enhancing charge transport. The distribution of finite energy levels of the bound system is sensitive to the ligand's binding site and the levels correspond to delocalized states. We also observed a trap state localized on a single Pb atom when a sulfur-containing phenyldithiocarbamate (PTC) ligand is attached to a slightly off-stoichiometric dot in a manner that the sulfur of the ligand completes stoichiometry of the bound system. Hence, this is indicative of the source of trap state when thio-based ligands are bound to chalcogenide nanocrystals. We also predict that titanyl phthalocyanine in a mix with chalcogenide dots of diameter ∼1.5 Å can form a donor-acceptor system.

Feasibility of contrast-enhanced ultrasound-guided biopsy of sentinel lymph nodes in dogs.

Science.gov (United States)

Gelb, Hylton R; Freeman, Lynetta J; Rohleder, Jacob J; Snyder, Paul W

2010-01-01

Our goal was to develop and validate a technique to identify the sentinel lymph nodes of the mammary glands of healthy dogs with contrast-enhanced ultrasound, and evaluate the feasibility of obtaining representative samples of a sentinel lymph node under ultrasound guidance using a new biopsy device. Three healthy intact female adult hounds were anesthetized and each received an injection of octafluoropropane-filled lipid microspheres and a separate subcutaneous injection of methylene blue dye around a mammary gland. Ultrasound was then used to follow the contrast agent through the lymphatic channel to the sentinel lymph node. Lymph node biopsy was performed under ultrasound guidance, followed by an excisional biopsy of the lymph nodes and a regional mastectomy procedure. Excised tissues were submitted for histopathologic examination and evaluated as to whether they were representative of the node. The ultrasound contrast agent was easily visualized with ultrasound leading up to the sentinel lymph nodes. Eight normal lymph nodes (two inguinal, one axillary in two dogs; two inguinal in one dog) were identified and biopsied. Lymphoid tissue was obtained from all biopsy specimens. Samples from four of eight lymph nodes contained both cortical and medullary lymphoid tissue. Contrast-enhanced ultrasound can be successfully used to image and guide minimally invasive biopsy of the normal sentinel lymph nodes draining the mammary glands in healthy dogs. Further work is needed to evaluate whether this technique may be applicable in patients with breast cancer or other conditions warranting evaluation of sentinel lymph nodes in animals.

Feasibility study of component risk ranking for plant maintenance

International Nuclear Information System (INIS)

Ushijima, Koji; Yonebayashi, Kenji; Narumiya, Yoshiyuki; Sakata, Kaoru; Kumano, Tetsuji

1999-01-01

Nuclear power is the base load electricity source in Japan, and reduction of operation and maintenance cost maintaining or improving plant safety is one of the major issues. Recently, Risk Informed Management (RIM) is focused as a solution. In this paper, the outline regarding feasibility study of component risk ranking for plant maintenance for a typical Japanese PWR plant is described. A feasibility study of component risk raking for plant maintenance optimization is performed on check valves and motor-operated valves. Risk ranking is performed in two steps using probabilistic analysis (quantitative method) for risk ranking of components, and deterministic examination (qualitative method) for component review. In this study, plant components are ranked from the viewpoint of plant safety / reliability, and the applicability for maintenance is assessed. As a result, distribution of maintenance resources using risk ranking is considered effective. (author)

Experimental Investigation on the Feasibility of Using a Fresnel Lens as a Solar-Energy Collection System for Enhancing On-Orbit Power Generation Performance

Directory of Open Access Journals (Sweden)

Tae-Yong Park

2017-01-01

Full Text Available Cube satellites have a limitation for generating power because of their cubic structure and extremely small size. In addition, the incidence angle between the sun and the solar panels continuously varies owing to the revolution and rotation of the satellite according to the attitude control strategy. This angle is an important parameter for determining the power generation performance of the cube satellite. In this study, we performed an experimental feasibility study that uses a Fresnel lens as a solar-energy collection system for cube satellite applications, so that the power generation efficiency can be enhanced under the worst incidence angle condition between the sun and solar panels by concentrating and redirecting solar energy onto the solar panels with a commercial Fresnel lens. To verify the effectiveness of the proposed system, we conducted a power-measurement test using a solar simulator and Fresnel lenses at various angles to the light source. In addition, we predicted the on-orbit power-generation enhancement achieved by employing the solar-energy collection system with various attitude control strategies.

A Feasibility Study of Youth Apprenticeship in Arkansas.

Science.gov (United States)

Jobs for the Future, Inc., West Somerville, MA.

A study assessed the feasibility and attractiveness of youth apprenticeship in Arkansas in over 80 interviews with employers in 5 key Arkansas industries and occupations. They were allied health, food processing (equipment repair and maintenance and lab technician/quality control), information services, metalworking, and self-employment and…

Mindfulness and Climate Change Action: A Feasibility Study

Directory of Open Access Journals (Sweden)

Maggie Grabow

2018-05-01

Full Text Available Pro-environmental behaviors and the cultural shifts that can accompany these may offer solutions to the consequences of a changing climate. Mindfulness has been proposed as a strategy to initiate these types of behaviors. In 2017, we pilot-tested Mindful Climate Action (MCA, an eight-week adult education program that delivers energy use, climate change, and sustainability content in combination with training in mindfulness meditation, among 16 individuals living in Madison, WI. We collected participant data at baseline and at different times across the study period regarding household energy use, transportation, diet, and health and happiness. This pilot study aimed to evaluate the feasibility of the various MCA study practices including measurement tools, outcome assessment, curriculum and related educational materials, and especially the mindfulness-based climate action trainings. MCA was well-received by participants as evidenced by high adherence rate, high measures of participant satisfaction, and high participant response rate for surveys. In addition, we successfully demonstrated feasibility of the MCA program, and have estimated participant’s individual carbon footprints related to diet, transportation, and household energy.

Technical Analysis Feasibility Study on Smart Microgrid System in Sekolah Tinggi Teknik PLN

Science.gov (United States)

Suyanto, Heri

2018-02-01

Nowadays application of new and renewable energy as main resource of power plant has greatly increased. High penetration of renewable energy into the grid will influence the quality and reliability of the electricity system, due to the intermittent characteristic of new and renewable energy resources. Smart grid or microgrid technology has the ability to deal with this intermittent characteristic especially if these renewable energy resources integrated to grid in large scale, so it can improve the reliability and efficiency of the grid. We plan to implement smart microgrid system at Sekolah Tinggi Teknik PLN as a pilot project. Before the pilot project start, the feasibility study must be conducted. In this feasibility study, the renewable energy resources and load characteristic at the site will be measured. Then the technical aspect of this feasibility study will be analyzed. This paper explains that analysis of ths feasibility study.

Methodology study: Co-generation feasibility at sawmills

International Nuclear Information System (INIS)

Host, J.

1991-01-01

This report discussed the various factors that should be studied and evaluated before establishing a cogeneration plant. The results of three case studies and a survey of energy needs in smaller and medium size sawmills are also presented. In general, cogeneration is feasible for supplying electric energy required for processing logs using fuelbark and other residues from the manufacturing process. A rebuilt turbine-generator unit is an initial cost saving alternative that is advantageous throughout the life of the operation

Apparent diffusion coefficient as it relates to histopathology findings in post-chemotherapy nephroblastoma: a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Littooij, Annemieke S. [University Medical Centre Utrecht/Wilhelmina Children' s Hospital, Department of Radiology and Nuclear Medicine, Utrecht (Netherlands); Nikkels, Peter G. [University Medical Centre Utrecht, Department of Pathology, Utrecht (Netherlands); Hulsbergen-van de Kaa, Christina A. [Radboud University Medical Centre, Department of Pathology, Nijmegen (Netherlands); Ven, Cees P. van de [Princess Maxima Centre for Paediatric Oncology, Department of Paediatric Surgery, Utrecht (Netherlands); Heuvel-Eibrink, Marry M. van den [Princess Maxima Centre for Paediatric Oncology, Department of Paediatric Oncology, Utrecht (Netherlands); Olsen, Oeystein E. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom)

2017-11-15

Nephroblastomas represent a group of heterogeneous tumours with variable proportions of distinct histopathological components. The purpose of this study was to investigate whether direct comparison of apparent diffusion coefficient (ADC) measurements with post-resection histopathology subtypes is feasible and whether ADC metrics are related to histopathological components. Twenty-three children were eligible for inclusion in this retrospective study. All children had MRI including diffusion-weighted imaging (DWI) after preoperative chemotherapy, just before tumour resection. A pathologist and radiologist identified corresponding slices at MRI and postoperative specimens using tumour morphology, the upper/lower calyx and hilar vessels as reference points. An experienced reader performed ADC measurements, excluding non-enhancing areas. A pathologist reviewed the corresponding postoperative slides according to the international standard guidelines. We tested potential associations with the Spearman rank test. Side-by-side comparison of MRI-DWI with corresponding histopathology slides was feasible in 15 transverse slices in 9 lesions in 8 patients. Most exclusions were related to extensive areas of necrosis/haemorrhage. In one lesion correlation was not possible because of the different orientation of sectioning of the specimen and MRI slices. The 25% ADC showed a strong relationship with percentage of blastema (Spearman rho=-0.71, P=0.003), whereas median ADC was strongly related to the percentage stroma (Spearman rho=0.74, P=0.002) at histopathology. Side-by-side comparison of MRI-DWI and histopathology is feasible in the majority of patients who do not have massive necrosis and hemorrhage. Blastemal and stromal components have a strong linear relationship with ADC markers. (orig.)

Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework.

Directory of Open Access Journals (Sweden)

Sandra M Eldridge

Full Text Available We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms 'pilot' and 'feasibility' in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms 'feasibility' or 'pilot' as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term 'feasibility' in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention.

Defining Feasibility and Pilot Studies in Preparation for Randomised Controlled Trials: Development of a Conceptual Framework.

Science.gov (United States)

Eldridge, Sandra M; Lancaster, Gillian A; Campbell, Michael J; Thabane, Lehana; Hopewell, Sally; Coleman, Claire L; Bond, Christine M

2016-01-01

We describe a framework for defining pilot and feasibility studies focusing on studies conducted in preparation for a randomised controlled trial. To develop the framework, we undertook a Delphi survey; ran an open meeting at a trial methodology conference; conducted a review of definitions outside the health research context; consulted experts at an international consensus meeting; and reviewed 27 empirical pilot or feasibility studies. We initially adopted mutually exclusive definitions of pilot and feasibility studies. However, some Delphi survey respondents and the majority of open meeting attendees disagreed with the idea of mutually exclusive definitions. Their viewpoint was supported by definitions outside the health research context, the use of the terms 'pilot' and 'feasibility' in the literature, and participants at the international consensus meeting. In our framework, pilot studies are a subset of feasibility studies, rather than the two being mutually exclusive. A feasibility study asks whether something can be done, should we proceed with it, and if so, how. A pilot study asks the same questions but also has a specific design feature: in a pilot study a future study, or part of a future study, is conducted on a smaller scale. We suggest that to facilitate their identification, these studies should be clearly identified using the terms 'feasibility' or 'pilot' as appropriate. This should include feasibility studies that are largely qualitative; we found these difficult to identify in electronic searches because researchers rarely used the term 'feasibility' in the title or abstract of such studies. Investigators should also report appropriate objectives and methods related to feasibility; and give clear confirmation that their study is in preparation for a future randomised controlled trial designed to assess the effect of an intervention.

Feasibility studies - Oesthammar, Nykoeping, Oskarshamn, Tierp, Hultsfred and Aelvkarleby. Summary report

International Nuclear Information System (INIS)

2001-06-01

Swedish Nuclear Fuel and Waste Management Company, SKB, has carried out feasibility studies on a municipal scale as a part of the siting programme for the deep repository for spent nuclear fuel. Final reports describing the results of the six feasibility studies in Oesthammar, Nykoeping, Oskarshamn, Tierp, Aelvkarleby and Hultsfred were submitted during the autumn and winter of 2000/2001. With this as a basis, the siting work can now proceed to the next phase - site investigations. In this stage, investigations that include test drilling will be conducted on at least two sites. In December 2000, SKB published the report 'Integrated account of method, site selection and programme prior to the site investigation phase', in which SKB stipulates where they want to conduct site investigations and how they will be carried out. The report is being reviewed by the Swedish Nuclear Power Inspectorate during the first half of 2001. Before the site investigations can be initiated,the go-ahead is required from the national safety authorities, the Government, and concerned municipalities and landowners. SKB projects that the it will be possible to commence the site investigations in 2002. This report comprises an English summary of the final reports from the six feasibility studies. The report summarizes the most important results and conclusions from the different feasibility studies. All six final reports are available in their entirety in Swedish

Feasibility studies - Oesthammar, Nykoeping, Oskarshamn, Tierp, Hultsfred and Aelvkarleby. Summary report

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-06-01

Swedish Nuclear Fuel and Waste Management Company, SKB, has carried out feasibility studies on a municipal scale as a part of the siting programme for the deep repository for spent nuclear fuel. Final reports describing the results of the six feasibility studies in Oesthammar, Nykoeping, Oskarshamn, Tierp, Aelvkarleby and Hultsfred were submitted during the autumn and winter of 2000/2001. With this as a basis, the siting work can now proceed to the next phase - site investigations. In this stage, investigations that include test drilling will be conducted on at least two sites. In December 2000, SKB published the report 'Integrated account of method, site selection and programme prior to the site investigation phase', in which SKB stipulates where they want to conduct site investigations and how they will be carried out. The report is being reviewed by the Swedish Nuclear Power Inspectorate during the first half of 2001. Before the site investigations can be initiated,the go-ahead is required from the national safety authorities, the Government, and concerned municipalities and landowners. SKB projects that the it will be possible to commence the site investigations in 2002. This report comprises an English summary of the final reports from the six feasibility studies. The report summarizes the most important results and conclusions from the different feasibility studies. All six final reports are available in their entirety in Swedish.

Pre-feasibility study of 80mw onshore wind farm

International Nuclear Information System (INIS)

Almas, M.S.

2014-01-01

This paper discusses a pre-feasibility study of 80MW onshore wind farm in the KPK (Khyber Pakhtunkhwa) province previously known as NWFP (North West Frontier) Province of Pakistan. The realistic data of wind speed is collected from Laboratory of Meteorology and Climatology (University of the Punjab) to study the feasibility of wind farm. Detailed analysis of wind turbines from four different manufacturers is carried out together with justifications of selecting a particular wind turbine. Issues related to site selection, wind farm civil foundation, recommendations for a particular choice of tower along with environmental effects are presented. Wind data analysis is carried out by using WINDROSE PRO software to determine the resultant direction of wind at the selected site for wind farm layout. The wind distribution at hub height of the wind turbine is calculated and is used to compute annual power production by the wind farm using power curves of the wind turbine. Electrical network integration issues of wind farm to the external grid are studied and the optimum point of connection is proposed. Finally, economic analysis of the whole wind farm project depending upon the LCC (Life Cycle Cost Analysis) is presented and the feasibility of the project from the investor's point of view is identified. The study concludes that the cost per kilowatt hour of electricity generated by this wind power plant will be 10.4 PKR/kWh and the payback period for the whole project is about 11.2 years. (author)

Dilator Use After Vaginal Brachytherapy for Endometrial Cancer: A Randomized Feasibility and Adherence Study.

Science.gov (United States)

Hanlon, Alexandra; Small, William; Strauss, Jonathan; Lin, Lilie L; Hanisch, Laura; Huang, Liming; Bai, Jinbing; Wells, Jessica; Bruner, Deborah Watkins

Vaginal brachytherapy, a common treatment of endometrial cancer, is associated with high rates of vaginal stenosis. Recommendations for vaginal dilator use to minimize stenosis generally include 3 times per week for approximately 10 minutes per use. However, adherence rates range widely and are generally well less than 50%. The aims of this study were to assess feasibility of recruitment to a study of dilator use and test a theoretically driven enhanced educational program (EEP) to increase adherence. Eligibility included women treated with postoperative vaginal brachytherapy for stage I to IIIc endometrial cancer. Patients were randomized to either nurse-delivered standard institutional instruction or EEP. Of eligible patients, 76% consented, 42 were randomized, and 69% completed the 6-month assessment. Mean age was 58.2 years; 48% were sexually active. There was no difference in adherence between arms. Overall, 20% and 8.3% were adherent to the prescribed use of 3 times per week, and 64% and 16% were adherent to use at least once per week at 6 weeks and 6 months, respectively. Adherence was greater among those motivated by vaginal health and having lower body mass index. Nonadherence was significantly higher among those who are college educated, in the EEP group, and with higher weight. Feasibility of recruitment into a study of vaginal dilator use was high. Adherence was low, and there was no difference between groups. Adherence to vaginal dilator use requires novel interventions to test. Nursing education that includes how dilators may maintain vaginal health may improve use because it was a motivator for adherence in this study.

Staging and storage facility feasibility study. Final report

International Nuclear Information System (INIS)

Swenson, C.E.

1995-02-01

This study was performed to investigate the feasibility of adapting the design of the HWVP Canister Storage Building (CSB) to meet the needs of the WHC Spent Nuclear Fuel Project for Staging and Storage Facility (SSF), and to develop Rough Order of Magnitude (ROM) cost and schedule estimates

Direct Current Combined With Bipolar Radiofrequency Ablation: An Ex Vivo Feasibility Study

International Nuclear Information System (INIS)

Tanaka, Toshihiro; Penzkofer, Tobias; Isfort, Peter; Bruners, Philipp; Disselhorst-Klug, Catherine; Junker, Elmar; Kichikawa, Kimihiko; Schmitz-Rode, Thomas; Mahnken, Andreas H.

2011-01-01

The combination of radiofrequency ablation (RFA) with direct current (DC) is a promising strategy to improve the efficiency of RFA. However, DC-enhanced monopolar RFA is limited by electrolytic injury at the positive-electrode site. The aim of this study was to investigate the feasibility of the DC-enhanced bipolar RFA. To obviate the need for the subcutaneous positive electrode, the DC circuit was combined with a commercially available bipolar RFA system, in which both poles of the DC circuit are connected to a single RF probe. DC was applied for 15 min and followed by RFA in bovine livers using the following various DC currents: (1) no DC (control), (2) 3V continued until the end of RFA, (3) 5V continued until the end of RFA, (4) 10V continued until the end of RFA, (5) 5V continued in the circuit with reversed pole, (6) 3V stopped after initiation of RFA, and (7) 5V stopped. Coagulation volume, temperatures at a distance of 5, 10, and 15 mm from the RF probe, mean amperage, ablation duration, applied energy, minimum impedance, and degree of tissue charring were assessed and compared (analysis of variance, Student–Newman–Keuls test). All combined DC and RFA groups did increase coagulation volume. The 10V continued group showed significantly lower applied energy, shortest ablation duration, highest minimum impedance, and highest degree of charring with the lowest coagulation volume (p < 0.05). DC-enhanced bipolar RFA with both poles of the DC circuit on a single probe appears to be ineffective.

Feasibility study: Assess the feasibility of siting a monitored retrievable storage facility. Phase 1

Energy Technology Data Exchange (ETDEWEB)

King, J.W.

1993-08-01

The purpose of phase one of this study are: To understand the waste management system and a monitored retrievable storage facility; and to determine whether the applicant has real interest in pursuing the feasibility assessment process. Contents of this report are: Generating electric power; facts about exposure to radiation; handling storage, and transportation techniques; description of a proposed monitored retrievable storage facility; and benefits to be received by host jurisdiction.

Feasibility study of full-reactor gas core demonstration test

Science.gov (United States)

Kunze, J. F.; Lofthouse, J. H.; Shaffer, C. J.; Macbeth, P. J.

1973-01-01

Separate studies of nuclear criticality, flow patterns, and thermodynamics for the gas core reactor concept have all given positive indications of its feasibility. However, before serious design for a full scale gas core application can be made, feasibility must be shown for operation with full interaction of the nuclear, thermal, and hydraulic effects. A minimum sized, and hence minimum expense, test arrangement is considered for a full gas core configuration. It is shown that the hydrogen coolant scattering effects dominate the nuclear considerations at elevated temperatures. A cavity diameter of somewhat larger than 4 ft (122 cm) will be needed if temperatures high enough to vaporize uranium are to be achieved.

Protocol for a feasibility randomised controlled trial of the use of Physical ACtivity monitors in an Exercise Referral Setting: the PACERS study.

Science.gov (United States)

Hawkins, Jemma; Edwards, Michelle; Charles, Joanna; Jago, Russell; Kelson, Mark; Morgan, Kelly; Murphy, Simon; Oliver, Emily; Simpson, Sharon; Edwards, Rhiannon Tudor; Moore, Graham

2017-01-01

Exercise referral schemes are recommended by the National Institute for Clinical Excellence (NICE) for physical activity promotion among inactive patients with health conditions or risk factors. Whilst there is evidence for the initial effectiveness and cost-effectiveness of such schemes for increasing physical activity, evidence of long-term effects is limited. Techniques such as goal setting, self-monitoring and personalised feedback may support motivation for physical activity. Technologies such as activity monitoring devices provide an opportunity to enhance delivery of motivational techniques. This paper describes the PACERS study protocol, which aims to assess the feasibility and acceptability of implementing an activity monitor within the existing Welsh National Exercise Referral Scheme (NERS) and proposed evaluation methodology for a full-scale randomised controlled trial. The PACERS study consists of a pilot randomised controlled trial, process evaluation and exploratory economic analyses. Participants will be recruited from the generic pathway of the Welsh NERS and will be randomly assigned to receive the intervention or usual practice. Usual practice is a 16-week structured exercise programme; the intervention consists of an accelerometry-based activity monitor (MyWellnessKey) and an associated web platform (MyWellnessCloud). The primary outcomes are predefined progression criteria assessing the acceptability and feasibility of the intervention and feasibility of the proposed evaluation methodology. Postal questionnaires will be completed at baseline (time 0: T0), 16 weeks after T0 (T1) and 12 months after T0 (T2). Routinely collected data will also be accessed at the same time points. A sub-sample of intervention participants and exercise referral staff will be interviewed following initiation of intervention delivery and at the end of the study. The PACERS study seeks to assess the feasibility of adding a novel motivational component to an existing

Virtual Non-Contrast CT Using Dual-Energy Spectral CT: Feasibility of Coronary Artery Calcium Scoring

OpenAIRE

Song, Inyoung; Yi, Jeong Geun; Park, Jeong Hee; Kim, Sung Mok; Lee, Kyung Soo; Chung, Myung Jin

2016-01-01

Objective To evaluate the feasibility of coronary artery calcium scoring based on three virtual noncontrast-enhanced (VNC) images derived from single-source spectral dual-energy CT (DECT) as compared with true noncontrast-enhanced (TNC) images. Materials and Methods This prospective study was conducted with the approval of our Institutional Review Board. Ninety-seven patients underwent noncontrast CT followed by contrast-enhanced chest CT using single-source spectral DECT. Iodine eliminated V...

Feasibility Study and Optimization of An Hybrid System (Eolian ...

African Journals Online (AJOL)

Feasibility Study and Optimization of An Hybrid System (Eolian- Photovoltaic - Diesel) With Provision of Electric Energy Completely Independent. ... reducing emissions of greenhouse gas (CO2 rate = 16086 kg / year for a system using only the generator diesel and is 599 kg / year for the stand alone hybrid system studied).

Differentiation between benign and malignant colon tumors using fast dynamic gadolinium-enhanced MR colonography; a feasibility study

DEFF Research Database (Denmark)

Achiam, M P; Andersen, L P H; Klein, M

2010-01-01

Colorectal cancer will present itself as a bowel obstruction in 16-23% of all cases. However, not all obstructing tumors are malignant and the differentiation between a benign and a malignant tumor can be difficult. The purpose of our study was to determine whether fast dynamic gadolinium-enhance...

Comparison of group-based outpatient physiotherapy with usual care after total knee replacement: a feasibility study for a randomized controlled trial.

Science.gov (United States)

Artz, Neil; Dixon, Samantha; Wylde, Vikki; Marques, Elsa; Beswick, Andrew D; Lenguerrand, Erik; Blom, Ashley W; Gooberman-Hill, Rachael

2017-04-01

To evaluate the feasibility of conducting a randomized controlled trial comparing group-based outpatient physiotherapy with usual care in patients following total knee replacement. A feasibility study for a randomized controlled trial. One secondary-care hospital orthopaedic centre, Bristol, UK. A total of 46 participants undergoing primary total knee replacement. The intervention group were offered six group-based exercise sessions after surgery. The usual care group received standard postoperative care. Participants were not blinded to group allocation. Feasibility was assessed by recruitment, reasons for non-participation, attendance, and completion rates of study questionnaires that included the Lower Extremity Functional Scale and Knee Injury and Osteoarthritis Outcome Score. Recruitment rate was 37%. Five patients withdrew or were no longer eligible to participate. Intervention attendance was high (73%) and 84% of group participants reported they were 'very satisfied' with the exercises. Return of study questionnaires at six months was lower in the usual care (75%) than in the intervention group (100%). Mean (standard deviation) Lower Extremity Functional Scale scores at six months were 45.0 (20.8) in the usual care and 57.8 (15.2) in the intervention groups. Recruitment and retention of participants in this feasibility study was good. Group-based physiotherapy was acceptable to participants. Questionnaire return rates were lower in the usual care group, but might be enhanced by telephone follow-up. The Lower Extremity Functional Scale had high responsiveness and completion rates. Using this outcome measure, 256 participants would be required in a full-scale randomized controlled trial.

Engineering management at feasibility study stage of nuclear power plant under EPC mode

International Nuclear Information System (INIS)

Wang Zhiqiang

2015-01-01

After the investment reform by the State Council in 2004, NDRC carries out approval system for enterprises to invest in nuclear power plants. Feasibility study stage is a critical stage on the mainline of nuclear power project approval, which intersects with the license application, and engineering design. The owners of nuclear power plants are required stringently in engineering management. From the owners' management point of view under EPC mode, this paper sorts the preliminary project process for nuclear power plants, focusing on the management in the feasibility study stage. License application and engineering design management in the feasibility study stage are also discussed. (author)

Impact of a family medicine resident wellness curriculum: a feasibility study

Directory of Open Access Journals (Sweden)

Christine Runyan

2016-06-01

Full Text Available Background: Up to 60% of practicing physicians report symptoms of burnout, which often peak during residency. Residency is also a relevant time for habits of self-care and resiliency to be emphasized. A growing literature underscores the importance of this; however, evidence about effective burnout prevention curriculum during residency remains limited. Objectives: The purpose of this project is to evaluate the impact of a new, 1-month wellness curriculum for 12 second-year family medicine residents on burnout, empathy, stress, and self-compassion. Methods: The pilot program, introduced during a new rotation emphasizing competencies around leadership, focused on teaching skills to cultivate mindfulness and self-compassion in order to enhance empathy and reduce stress. Pre-assessments and 3-month follow-up assessments on measures of burnout, empathy, self-compassion, and perceived stress were collected to evaluate the impact of the curriculum. It was hypothesized that this curriculum would enhance empathy and self-compassion as well as reduce stress and burnout among family medicine residents. Results: Descriptive statistics revealed positive trends on the mean scores of all the measures, particularly the Mindfulness Scale of the Self-Compassion Inventory and the Jefferson Empathy Scale. However, the small sample size and lack of sufficient power to detect meaningful differences limited the use of inferential statistics. Conclusions: This feasibility study demonstrates how a residency wellness curriculum can be developed, implemented, and evaluated with promising results, including high participant satisfaction.

Feasibility Study on Solar District Heating in China

DEFF Research Database (Denmark)

Huang, Junpeng; Fan, Jianhua; Furbo, Simon

This paper analyzes the feasibility of developing solar district heating (SDH) in China from the perspective of incentive policy, selections of technical route, regional adaptability and economic feasibility for clean heating. Based on the analyzation, this proposes a road map for the development...

[Cambridge Conference on School Mathematics Feasibility Studies 9-13.

Science.gov (United States)

Cambridge Conference on School Mathematics, Newton, MA.

These materials are a part of a series of studies sponsored by the Cambridge Conference on School Mathematics which reflects the ideas of CCSM regarding the goals and objectives for school mathematics K-12. Feasibility Studies 9-13 contain a wide range of topics. The following are the titles and brief descriptions of these studies. Number…

PERFECTED enhanced recovery (PERFECT-ER) care versus standard acute care for patients admitted to acute settings with hip fracture identified as experiencing confusion: study protocol for a feasibility cluster randomized controlled trial.

Science.gov (United States)

Hammond, Simon P; Cross, Jane L; Shepstone, Lee; Backhouse, Tamara; Henderson, Catherine; Poland, Fiona; Sims, Erika; MacLullich, Alasdair; Penhale, Bridget; Howard, Robert; Lambert, Nigel; Varley, Anna; Smith, Toby O; Sahota, Opinder; Donell, Simon; Patel, Martyn; Ballard, Clive; Young, John; Knapp, Martin; Jackson, Stephen; Waring, Justin; Leavey, Nick; Howard, Gregory; Fox, Chris

2017-12-04

Health and social care provision for an ageing population is a global priority. Provision for those with dementia and hip fracture has specific and growing importance. Older people who break their hip are recognised as exceptionally vulnerable to experiencing confusion (including but not exclusively, dementia and/or delirium and/or cognitive impairment(s)) before, during or after acute admissions. Older people experiencing hip fracture and confusion risk serious complications, linked to delayed recovery and higher mortality post-operatively. Specific care pathways acknowledging the differences in patient presentation and care needs are proposed to improve clinical and process outcomes. This protocol describes a multi-centre, feasibility, cluster-randomised, controlled trial (CRCT) to be undertaken across ten National Health Service hospital trusts in the UK. The trial will explore the feasibility of undertaking a CRCT comparing the multicomponent PERFECTED enhanced recovery intervention (PERFECT-ER), which acknowledges the differences in care needs of confused older patients experiencing hip fracture, with standard care. The trial will also have an integrated process evaluation to explore how PERFECT-ER is implemented and interacts with the local context. The study will recruit 400 hip fracture patients identified as experiencing confusion and will also recruit "suitable informants" (individuals in regular contact with participants who will complete proxy measures). We will also recruit NHS professionals for the process evaluation. This mixed methods design will produce data to inform a definitive evaluation of the intervention via a large-scale pragmatic randomised controlled trial (RCT). The trial will provide a preliminary estimate of potential efficacy of PERFECT-ER versus standard care; assess service delivery variation, inform primary and secondary outcome selection, generate estimates of recruitment and retention rates, data collection difficulties, and

Space shuttle/food system study. Package feasibility study, modifications 3S, 4C and 5S

Science.gov (United States)

1974-01-01

An optimum feeding system for the space shuttle was presented. This system consisted of all rehydratable type foods which were enclosed in a 4 in. x 4 in. x 1 in. flexible package. A feasibility follow-on study was conducted, and two acceptable, feasible prototypes for this package are described.

Whose Frames Mattered? The Feasibility Study in the Municipality of Tierp 1998-2000

International Nuclear Information System (INIS)

Johansson, Hanna Sofia

2003-01-01

In December 2001 SKB (the Swedish Nuclear Fuel and Waste Management Co) presented a ranking list of the eight feasibility studies carried out in Sweden. The feasibility study in Tierp was cited as showing that potentially good bedrock could be found in the municipality and SKB therefore asked to carry out a site investigation. Tierp is a neighbouring municipality to Oesthammar, a municipality that hosts nuclear power plants, with around 20,000 inhabitants and an area of 1543 km 2 . This paper focuses on why the Municipal Council in Tierp voted 'no' to further investigations even though SKB pointed out the municipality as having potentially good bedrock. In 1998 a feasibility study in Tierp was started. The arguments presented for a feasibility study were: the proximity to Forsmark nuclear power plant in Oesthammar, responsibilities for future generations, and that an investigation of the municipality could be used for other purposes. The main question this paper asks is the following: why did the Municipal Council in Tierp say 'no' to further investigations? This question is of interest since SKB claimed that Tierp had potentially good bedrock. The hypothesis is that the democratic models (representative democracy, discursive democracy or technocracy) present in the feasibility study and the boundary work carried out, i.e. how the boundary between science and politics was drawn, and which actors had access to the discussion on the public agenda, influenced the decision of the Council. The main sources used are interviews and a Swedish governmental investigation report about the feasibility studies. Twelve fairly open interviews with actors from the municipal organization, SKB, local opinion groups and the media were carried out. The questions cover how hey worked with the study, how the municipality organized its work, how they defined the nuclear waste issues and how they tried to communicate their views to other actors

Feasibility study of Boron Nitride coating on Lithium-ion battery casing

International Nuclear Information System (INIS)

Saw, L.H.; Ye, Y.; Tay, A.A.O.

2014-01-01

Increasing in public awareness about global warming and exhaustion of energy resources has led to a flourishing electric vehicle industry that would help realize a zero-emission society. The thermal management of battery packs, which is an essential issue closely linked to a number of challenges for electric vehicles including cost, safety, reliability and lifetime, has been extensively studied. However, relatively little is known about the thermal effect of polymer insulation on the Lithium-ion battery casing. This study investigates the feasibility of replacing the polymer insulation with a Boron Nitride coating on the battery casing using the Taguchi experimental method. The effect of casing surface roughness, coating thickness and their interaction were examined using orthogonal array L 9 (3 4 ). Nominal the best is chosen for the optimization process to achieve optimum adhesion strength. In addition, the thermal improvements of the coating as compared to conventional polymer insulator on the battery are further investigated. - Highlights: • We studied the Boron Nitride coating on battery casing using Taguchi method. • We investigated the effect of surface roughness and coating thickness on adhesion strength. • We compared the effect of coating and polymer insulator in heat transfer. • The Boron Nitride coating could enhance the thermal management of the battery

Pre-Feasibility Study of 80MW Onshore Wind Farm

Directory of Open Access Journals (Sweden)

Muhammad Shoaib Almas

2014-10-01

Full Text Available This paper discusses a pre-feasibility study of 80MW onshore wind farm in the KPK (Khyber Pakhtunkhwa province previously known as NWFP (North West Frontier Province of Pakistan. The realistic data of wind speed is collected from Laboratory of Meteorology & Climatology (University of the Punjab to study the feasibility of wind farm. Detailed analysis of wind turbines from four different manufacturers is carried out together with justifications of selecting a particular wind turbine. Issues related to site selection, wind farm civil foundation, recommendations for a particular choice of tower along with environmental effects are presented. Wind data analysis is carried out by using WINDROSE PRO software to determine the resultant direction of wind at the selected site for wind farm layout. The wind distribution at hub height of the wind turbine is calculated and is used to compute annual power production by the wind farm using power curves of the wind turbine. Electrical network integration issues of wind farm to the external grid are studied and the optimum point of connection is proposed. Finally, economic analysis of the whole wind farm project depending upon the LCC (Life Cycle Cost Analysis is presented and the feasibility of the project from the investor?s point of view is identified. The study concludes that the cost per kilowatt hour of electricity generated by this wind power plant will be 10.4 PKR/kWh and the payback period for the whole project is about 11.2 years

Feasibility of using intravenous contrast-enhanced computed tomography (CT) scans in lung cancer treatment planning

International Nuclear Information System (INIS)

Xiao Jianghong; Zhang Hong; Gong Youling; Fu Yuchuan; Tang Bin; Wang Shichao; Jiang Qingfeng; Li Ping

2010-01-01

Background and purpose: To investigate the feasibility of using intravenous contrast-enhanced computed tomography (CT) scans in 3-dimensional conformal radiotherapy (3D-CRT), stereotactic body radiation therapy (SBRT) and intensity-modulated radiotherapy (IMRT) treatment planning for lung cancers, respectively. Materials and methods: Twelve patients with bulky lung tumors and 14 patients with small lung tumors were retrospectively analyzed. Each patient took two sets of CT in the same position with active breathing control (ABC) technique before and after intravenous contrast agent (CA) injections. Bulky tumors were planned with 3D-CRT, while SBRT plans were generated for patients with small tumors based on CT scans with intravenous CA. In addition, IMRT plans were generated for patients with bulky tumors to continue on a planning study. All plans were copied and replaced on the scans without intravenous CA. The radiation doses calculated from the two sets of CTs were compared with regard to planning volumes (PTV), the organ at-risk (OAR) and the lungs using Wilcoxon's signed rank test. Results: In comparisons for 3D-CRT plans, CT scans with intravenous CA reduced the mean dose and the maximum dose of PTV with significant differences (p 95 ) for targets, respectively (p < 0.05). There was no statistical significance for lung parameters between two sets of scans in SBRT plans and IMRT plans. Conclusions: The enhanced CT scans can be used for both target delineation and treatment planning in 3D-CRT. The dose difference caused by intravenous CA is small. But for SBRT and IMRT, the minimum irradiation dose in targets may be estimated to be increased up to 2.71% while the maximum dose may be estimated to be decreased up to 1.36%. However, the difference in dose distribution in most cases were found to be clinical tolerable.

An augmented reality system for upper-limb post-stroke motor rehabilitation: a feasibility study.

Science.gov (United States)

Assis, Gilda Aparecida de; Corrêa, Ana Grasielle Dionísio; Martins, Maria Bernardete Rodrigues; Pedrozo, Wendel Goes; Lopes, Roseli de Deus

2016-08-01

To determine the clinical feasibility of a system based on augmented reality for upper-limb (UL) motor rehabilitation of stroke participants. A physiotherapist instructed the participants to accomplish tasks in augmented reality environment, where they could see themselves and their surroundings, as in a mirror. Two case studies were conducted. Participants were evaluated pre- and post-intervention. The first study evaluated the UL motor function using Fugl-Meyer scale. Data were compared using non-parametric sign tests and effect size. The second study used the gain of motion range of shoulder flexion and abduction assessed by computerized biophotogrammetry. At a significance level of 5%, Fugl-Meyer scores suggested a trend for greater UL motor improvement in the augmented reality group than in the other. Moreover, effect size value 0.86 suggested high practical significance for UL motor rehabilitation using the augmented reality system. System provided promising results for UL motor rehabilitation, since enhancements have been observed in the shoulder range of motion and speed. Implications for Rehabilitation Gain of range of motion of flexion and abduction of the shoulder of post-stroke patients can be achieved through an augmented reality system containing exercises to promote the mental practice. NeuroR system provides a mental practice method combined with visual feedback for motor rehabilitation of chronic stroke patients, giving the illusion of injured upper-limb (UL) movements while the affected UL is resting. Its application is feasible and safe. This system can be used to improve UL rehabilitation, an additional treatment past the traditional period of the stroke patient hospitalization and rehabilitation.

A neuromechanics-based powered ankle exoskeleton to assist walking post-stroke: a feasibility study.

Science.gov (United States)

Takahashi, Kota Z; Lewek, Michael D; Sawicki, Gregory S

2015-02-25

In persons post-stroke, diminished ankle joint function can contribute to inadequate gait propulsion. To target paretic ankle impairments, we developed a neuromechanics-based powered ankle exoskeleton. Specifically, this exoskeleton supplies plantarflexion assistance that is proportional to the user's paretic soleus electromyography (EMG) amplitude only during a phase of gait when the stance limb is subjected to an anteriorly directed ground reaction force (GRF). The purpose of this feasibility study was to examine the short-term effects of the powered ankle exoskeleton on the mechanics and energetics of gait. Five subjects with stroke walked with a powered ankle exoskeleton on the paretic limb for three 5 minute sessions. We analyzed the peak paretic ankle plantarflexion moment, paretic ankle positive work, symmetry of GRF propulsion impulse, and net metabolic power. The exoskeleton increased the paretic plantarflexion moment by 16% during the powered walking trials relative to unassisted walking condition (p exoskeleton assistance appeared to reduce the net metabolic power gradually with each 5 minute repetition, though no statistical significance was found. In three of the subjects, the paretic soleus activation during the propulsion phase of stance was reduced during the powered assistance compared to unassisted walking (35% reduction in the integrated EMG amplitude during the third powered session). This feasibility study demonstrated that the exoskeleton can enhance paretic ankle moment. Future studies with greater sample size and prolonged sessions are warranted to evaluate the effects of the powered ankle exoskeleton on overall gait outcomes in persons post-stroke.

How to Train an Injured Brain? A Pilot Feasibility Study of Home-Based Computerized Cognitive Training.

Science.gov (United States)

Verhelst, Helena; Vander Linden, Catharine; Vingerhoets, Guy; Caeyenberghs, Karen

2017-02-01

Computerized cognitive training programs have previously shown to be effective in improving cognitive abilities in patients suffering from traumatic brain injury (TBI). These studies often focused on a single cognitive function or required expensive hardware, making it difficult to be used in a home-based environment. This pilot feasibility study aimed to evaluate the feasibility of a newly developed, home-based, computerized cognitive training program for adolescents who suffered from TBI. Additionally, feasibility of study design, procedures, and measurements were examined. Case series, longitudinal, pilot, feasibility intervention study with one baseline and two follow-up assessments. Nine feasibility outcome measures and criteria for success were defined, including accessibility, training motivation/user experience, technical smoothness, training compliance, participation willingness, participation rates, loss to follow-up, assessment timescale, and assessment procedures. Five adolescent patients (four boys, mean age = 16 years 7 months, standard deviation = 9 months) with moderate to severe TBI in the chronic stage were recruited and received 8 weeks of cognitive training with BrainGames. Effect sizes (Cohen's d) were calculated to determine possible training-related effects. The new cognitive training intervention, BrainGames, and study design and procedures proved to be feasible; all nine feasibility outcome criteria were met during this pilot feasibility study. Estimates of effect sizes showed small to very large effects on cognitive measures and questionnaires, which were retained after 6 months. Our pilot study shows that a longitudinal intervention study comprising our novel, computerized cognitive training program and two follow-up assessments is feasible in adolescents suffering from TBI in the chronic stage. Future studies with larger sample sizes will evaluate training-related effects on cognitive functions and underlying brain structures.

The Use of Market Feasibility Studies in the Restaurant Industry for Small and Medium-sized Restaurants

OpenAIRE

Kolster, Maria

2017-01-01

The goals of this thesis are to provide the reader with new information about market feasibility studies in the restaurant industry and to design a market feasibility template for the international restaurant industry which can be used for small and medium-sized restaurants before entering the market. The objectives are to define the ideal factors of a market feasibility study for the international restaurant industry, to learn and become an expert in feasibility studies for the restaurant i...

Feasibility study on production of Co-60 in PHWR

Energy Technology Data Exchange (ETDEWEB)

Park, Kyung Bae; Han, Hyon Soo; Joo, Po Kook

2000-05-01

The purpose of this study is to analyze the safeties and the economics for Co-60 production from Wolsung PHWR and to verify the feasibility on the manufacturing of the final Co-60 source for industrial irradiation. The feasibility of reactor conversion was carried out with KEPCO collaboration. Through the site survey on the experience of Gentililly-2 in Canada, a feasibility of plant conversion, changes in design, equipment and tools for Co-60 production was verified. It was estimated that the reactor conversion would not impose adverse impact on plant safety. For the encapsulation of radiation source and storage of the final products, a modification of concrete hot cell at KAERI was primary concerns. The installation and improvement of facilities are needed to avoid cross contamination and extra radiation exposure. Main items for these are pressure gauge, separated HEPA filter the ceiling separation, extra-shielding and ceiling hoist system. At present, storage pool has got admission based on 400 kCi. But it is necessary to seismic analysis and design improvement of shielding to store 10 MCi (Co-60) which is the estimated Co-60 capacity produced by 3 PHWRs. According to present investigation, a production of Co-60 by PHWR and RIPE was seemed to be an economically feasible business and it was also expected that a joint venture will be able to realize by cooperation with MDS Nordion Co.

Feasibility study on production of Co-60 in PHWR

International Nuclear Information System (INIS)

Park, Kyung Bae; Han, Hyon Soo; Joo, Po Kook

2000-05-01

The purpose of this study is to analyze the safeties and the economics for Co-60 production from Wolsung PHWR and to verify the feasibility on the manufacturing of the final Co-60 source for industrial irradiation. The feasibility of reactor conversion was carried out with KEPCO collaboration. Through the site survey on the experience of Gentililly-2 in Canada, a feasibility of plant conversion, changes in design, equipment and tools for Co-60 production was verified. It was estimated that the reactor conversion would not impose adverse impact on plant safety. For the encapsulation of radiation source and storage of the final products, a modification of concrete hot cell at KAERI was primary concerns. The installation and improvement of facilities are needed to avoid cross contamination and extra radiation exposure. Main items for these are pressure gauge, separated HEPA filter the ceiling separation, extra-shielding and ceiling hoist system. At present, storage pool has got admission based on 400 kCi. But it is necessary to seismic analysis and design improvement of shielding to store 10 MCi (Co-60) which is the estimated Co-60 capacity produced by 3 PHWRs. According to present investigation, a production of Co-60 by PHWR and RIPE was seemed to be an economically feasible business and it was also expected that a joint venture will be able to realize by cooperation with MDS Nordion Co

Feasibility study of structured diagnosis methods for functional dyspepsia in Korean medicine clinics

Directory of Open Access Journals (Sweden)

Jeong Hwan Park

2017-12-01

Full Text Available Background: Functional dyspepsia (FD is the seventh most common disease encountered in Korean medicine (KM clinics. Despite the large number of FD patients visiting KM clinics, the accumulated medical records have no utility in evidence development, due to being unstructured. This study aimed to construct a standard operating procedure (SOP with appropriate structured diagnostic methods for FD, and assess the feasibility for use in KM clinics. Methods: Two rounds of professional surveys were conducted by 10 Korean internal medicine professors to select the representative diagnostic methods. A feasibility study was conducted to evaluate compliance and time required for using the structured diagnostic methods by three specialists in two hospitals. Results: As per the results of the professional survey, five questionnaires and one basic diagnostic method were selected. An SOP was constructed based on the survey results, and a feasibility study showed that the SOP compliance score (out of 5 was 3.45 among the subjects, and 3.25 among the practitioners. The SOP was acceptable and was not deemed difficult to execute. The total execution time was 136.5 minutes, out of which the gastric emptying test time was 129 minutes. Conclusion: This feasibility study of the SOP with structured diagnostic methods for FD confirmed it was adequate for use in KM clinics. It is expected that these study findings will be helpful to clinicians who wish to conduct observational studies as well as to generate quantitative medical records to facilitate Big Data research. Keywords: Big Data, Dyspepsia, Korean medicine, Feasibility studies, Observational study

Feasibility study of gasification of oil palm fronds

Directory of Open Access Journals (Sweden)

S.A. Sulaiman

2015-12-01

Full Text Available Considering the large and consistent supply, oil palm fronds could be a promising source of biomass energy through gasification. There is very scarce information on the characteristics of oil palm fronds, which is vital in deciding if such biomass is technically suitable for gasification. In the present work, the feasibility of oil palm fronds for biomass gasification is studied. The study is conducted experimentally via standard tests to determine their thermochemical characteristics. Ultimate analysis is conducted to determine the contents of carbon, nitrogen, hydrogen and sulphide in oil palm fronds. Proximate analysis is performed to identify the burning characteristics of the biomass. The energy content in the fronds is determined by using a bomb calorie meter and is around 18 MJ/kg. The ignitability of the fronds is also studied experimentally to assess the ease to start-up combustion of the fronds. The characteristics of the flame of the resulting syngas from gasification of oil palm fronds are qualitatively studied. Simulated syngas composition study reveals potentials of 22% CO, 1.3% H2, 18.5% CO2 and traces of CH4. The study is extended to computer simulation to predict composition of the syngas. It is found from this work that oil palm fronds are feasible for gasification and has a good potential as a renewable energy source.

Optical Coherence Tomography of the Breast: A Feasibility Study

National Research Council Canada - National Science Library

Connolly, James

2003-01-01

.... This novel imaging technology has the potential to improve cancer detection and diagnosis. The aim of this study was to determine the feasibility of applying OCT imaging to normal and pathologic human breast tissue, as well as other human tissues...

Optical Coherence Tomography of the Breast: A Feasibility Study

National Research Council Canada - National Science Library

Connolly, James L

2005-01-01

.... This novel imaging technology has the potential to improve cancer detection and diagnosis. The aim of this study was to determine the feasibility of applying OCT imaging to normal and pathologic human breast tissue, as well as other human tissues...

Structured Narrative Retell Instruction for Young Children from Low Socioeconomic Backgrounds: A Preliminary Study of Feasibility

Directory of Open Access Journals (Sweden)

Suzanne M Adlof

2014-05-01

Full Text Available Successful acquisition of literacy depends on adequate development of decoding skills as well as broader, meaning-related knowledge and skills for text comprehension. Children from low socioeconomic status (SES backgrounds are often challenged in both domains, relative to peers who are not economically disadvantaged. The efficacy of code-focused instructional programs for at-risk preliterate children is well supported, but less evidence is available regarding interventions to improve broader language and comprehension skills. This preliminary study tested the feasibility of a new intervention, structured narrative retell instruction (SNRI, and explored its potential to enhance meaning-related knowledge and skills, including vocabulary, listening comprehension, and narrative skills, in pre-literate, low SES children. SNRI used authentic children’s books to model comprehension processes, explicitly teach story grammar, and implicitly target microstructural aspects of narratives. Participants included 9 children with a mean age of 60 months, who were randomly assigned to SNRI or to code-focused literacy instruction (CFLI. Each group received 12, 40-minute instructional sessions over six weeks. Pre- and posttests were administered to assess vocabulary, listening comprehension, narrative macrostructure and narrative microstructure, as well as alphabet knowledge, phonological awareness, and concepts of print. The feasibility of SNRI was demonstrated by completion of the designed study, moderately high treatment fidelity, and qualitative feedback from interventionists. The SNRI group also made significant gains on four of the seven meaning-related measures (p < .10. In comparison, the CFLI group made significant gains on two of seven meaning-related measures. We conclude that SNRI is feasible and shows potential for improving language skills related to comprehension and that further research investigating its efficacy is warranted.

Depleted uranium concrete container feasibility study

International Nuclear Information System (INIS)

Haelsig, R.T.

1994-09-01

The purpose of this report is to consider the feasibility of using containers constructed of depleted uranium aggregate concrete (DUCRETE) to store and transport radioactive materials. The method for this study was to review the advantages and disadvantages of DUCRETE containers considering design requirements for potential applications. The author found that DUCRETE is a promising material for onsite storage containers, provided DUCRETE vessels can be certified for one-way transport to disposal sites. The author also found that DUCRETE multipurpose spent nuclear fuel storage/transport packages are technically viable, provided altered temperature acceptance limits can be developed for DUCRETE

Computer-Based Job and Occupational Data Collection Methods: Feasibility Study

National Research Council Canada - National Science Library

Mitchell, Judith I

1998-01-01

.... The feasibility study was conducted to assess the operational and logistical problems involved with the development, implementation, and evaluation of computer-based job and occupational data collection methods...

Construction monitoring constraints and challenges:A feasibility study

OpenAIRE

Fidler, Paul; Vardanega, Paul J; Long, Peter; Webb, Graham; Stehle, John; Middleton, Campbell

2013-01-01

This paper presents a study of the constraints and challenges faced by the authors when invited to study the feasibility of developing a monitoring system to provide specific information sought by the designer and contractor during the construction of the new 225m high, 48 storey steel-framed Leadenhall Building, located at 122 Leadenhall Street in London. The original goal of the study was to develop a system to assist with the active alignment of the building during construction, a key aim ...

Full system decontamination feasibility studies

International Nuclear Information System (INIS)

Denault, R.P.; LeSurf, J.E.; Walschot, F.W.

1988-01-01

Many chemical decontaminations have been performed on subsystems in light water reactors (BWRs and PWRs) but none on the full system (including the fuel) of large, (>500 MWe) investor owned reactors. Full system decontaminations on pressure-tubed reactors have been shown to facilitate maintenance, inspection, repair and replacement of reactor components. Further advantages are increased reactor availability and plant life extension. A conceptual study has been performed for EPRI (for PWRs) and Commonwealth Edison Co (for BWRs) into the applicability and cost benefit of full system decontaminations (FSD). The joint study showed that FSDs in both PWRs and BWRs, with or without the fuel included in the decontamination, are feasible and cost beneficial provided a large amount of work is to be done following the decontamination. The large amounts of radioactive waste generated can be managed using current technologies. Considerable improvements in waste handling, and consequent cost savings, can be obtained if new techniques which are now reaching commercial application are used. (author)

Lunar Wireless Power Transfer Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Freid, Sheldon [National Security Technologies, LLC. (NSTec), Mercury, NV (United States); Popovic, Zoya [Univ. of Colorado, Boulder, CO (United States); Beckett, David R. [Independent Consultant; Anderson, Scott R. [Independent Consultant; Mann, Diana [Independent Consultant; Walker, Stuart [Independent Consultant

2008-03-01

This study examines the feasibility of a multi-kilowatt wireless radio frequency (RF) power system to transfer power between lunar base facilities. Initial analyses, show that wireless power transfer (WPT) systems can be more efficient and less expensive than traditional wired approaches for certain lunar and terrestrial applications. The study includes evaluations of the fundamental limitations of lunar WPT systems, the interrelationships of possible operational parameters, and a baseline design approach for a notionial system that could be used in the near future to power remote facilities at a lunar base. Our notional system includes state-of-the-art photovoltaics (PVs), high-efficiency microwave transmitters, low-mass large-aperture high-power transmit antennas, high-efficiency large-area rectenna receiving arrays, and reconfigurable DC combining circuitry.

Feasibility Study of Renewable Energy in Singapore

OpenAIRE

King, Sebastian; Wettergren, Per

2011-01-01

Singapore is a country that is currently highly dependent on import of oil and gas. In order to be able to shift into a more sustainable energy system, Singapore is investing in research regarding different technologies and systems so as to establish more sustainable energy solutions. Seeing how air-conditioning accounts for approximately 30 % of Singapore’s total energy consumption, a feasibility study is being conducted on whether an integrated system using a thermally active building syste...

Promoting student case creation to enhance instruction of clinical reasoning skills: a pilot feasibility study.

Science.gov (United States)

Chandrasekar, Hamsika; Gesundheit, Neil; Nevins, Andrew B; Pompei, Peter; Bruce, Janine; Merrell, Sylvia Bereknyei

2018-01-01

It is a common educational practice for medical students to engage in case-based learning (CBL) exercises by working through clinical cases that have been developed by faculty. While such faculty-developed exercises have educational strengths, there are at least two major drawbacks to learning by this method: the number and diversity of cases is often limited; and students decrease their engagement with CBL cases as they grow accustomed to the teaching method. We sought to explore whether student case creation can address both of these limitations. We also compared student case creation to traditional clinical reasoning sessions in regard to tutorial group effectiveness, perceived gains in clinical reasoning, and quality of student-faculty interaction. Ten first-year medical students participated in a feasibility study wherein they worked in small groups to develop their own patient case around a preassigned diagnosis. Faculty provided feedback on case quality afterwards. Students completed pre- and post-self-assessment surveys. Students and faculty also participated in separate focus groups to compare their case creation experience to traditional CBL sessions. Students reported high levels of team engagement and peer learning, as well as increased ownership over case content and understanding of clinical reasoning nuances. However, students also reported decreases in student-faculty interaction and the use of visual aids ( P study suggest that student-generated cases can be a valuable adjunct to traditional clinical reasoning instruction by increasing content ownership, encouraging student-directed learning, and providing opportunities to explore clinical nuances. However, these gains may reduce student-faculty interaction. Future studies may be able to identify an improved model of faculty participation, the ideal timing for incorporation of this method in a medical curriculum, and a more rigorous assessment of the impact of student case creation on the

Impact of bottle size on in-home consumption of sugar-sweetened beverages: a feasibility and acceptability study.

Science.gov (United States)

Mantzari, Eleni; Hollands, Gareth J; Pechey, Rachel; Jebb, Susan; Marteau, Theresa M

2017-04-07

Consumption of sugars-sweetened beverages (SSB) increases energy intake and the risk of obesity. Large packages increase consumption of food, implying that smaller bottle sizes may help curb SSB consumption, but there is a lack of relevant evidence relating to these products. This study explores the feasibility and acceptability of conducting a randomised controlled trial to assess the impact of different bottle sizes on SSB consumption at home. Households in Cambridge, England, which purchased at least 2 l of regular cola drinks per week, received a set amount of cola each week for four weeks, in bottles of one of four sizes (1500 ml, 1000 ml, 500 ml, or 250 ml) in random order. The total volume received consisted of a modest excess of households' typical weekly purchasing, but was further increased for half the study households to avoid ceiling effects. Consumption was measured by recording the number of empty bottles at the end of each week. Eligible households were invited to complete a run-in period to assess levels of active participation. Thirty-seven of 111 eligible households with an interest in the study completed the run-in period. The study procedures proved feasible. The target for recruitment (n = 16 households) was exceeded. Measuring consumption was feasible: over three quarters (n = 30/37) of households returned all bottles on the majority (n = 88/101) of the study weeks completed across households. The validity of this measure was compromised by guests from outside the household who drank the study cola (n = 18/37 households on 48/101 study weeks) and consumption of the study cola outside the home. Supplying enhanced volumes of cola to nine households was associated with higher consumption (11,592 ml vs 7869 ml). The intervention and study procedures were considered acceptable. Thirteen households correctly identified the study aims. The findings support the feasibility and acceptability of running a randomised controlled trial to

Impact of bottle size on in-home consumption of sugar-sweetened beverages: a feasibility and acceptability study

Directory of Open Access Journals (Sweden)

Eleni Mantzari

2017-04-01

Full Text Available Abstract Background Consumption of sugars-sweetened beverages (SSB increases energy intake and the risk of obesity. Large packages increase consumption of food, implying that smaller bottle sizes may help curb SSB consumption, but there is a lack of relevant evidence relating to these products. This study explores the feasibility and acceptability of conducting a randomised controlled trial to assess the impact of different bottle sizes on SSB consumption at home. Methods Households in Cambridge, England, which purchased at least 2 l of regular cola drinks per week, received a set amount of cola each week for four weeks, in bottles of one of four sizes (1500 ml, 1000 ml, 500 ml, or 250 ml in random order. The total volume received consisted of a modest excess of households’ typical weekly purchasing, but was further increased for half the study households to avoid ceiling effects. Consumption was measured by recording the number of empty bottles at the end of each week. Eligible households were invited to complete a run-in period to assess levels of active participation. Results Thirty-seven of 111 eligible households with an interest in the study completed the run-in period. The study procedures proved feasible. The target for recruitment (n = 16 households was exceeded. Measuring consumption was feasible: over three quarters (n = 30/37 of households returned all bottles on the majority (n = 88/101 of the study weeks completed across households. The validity of this measure was compromised by guests from outside the household who drank the study cola (n = 18/37 households on 48/101 study weeks and consumption of the study cola outside the home. Supplying enhanced volumes of cola to nine households was associated with higher consumption (11,592 ml vs 7869 ml. The intervention and study procedures were considered acceptable. Thirteen households correctly identified the study aims. Conclusion The findings support the feasibility

Computing with words to feasibility study of software projects

Directory of Open Access Journals (Sweden)

Marieta Peña Abreu

2017-02-01

Full Text Available Objective: This paper proposes a method to analyze the technical, commercial and social feasibility of software projects in environments of uncertainty. It allows working with multiple experts and multiple criteria and facilitates decision-making. Method: The proposal contains two phases, first the necessary information is collected and in second place projects are evaluated using 2-tuple linguistic representation model. The experts are selected by analyzing their curricular synthesis. The evaluation criteria are defined using the technique Focus Group and weighted in the interval (0,1 according to their importance. three domains are offered to express the preferences: numeric, interval-valued and linguistic. For aggregation extended arithmetic mean and weighted average extended are used, preventing the loss of information. A 2-tuple (feasibility, precision is obtained as a result for each project. Results: The evaluation of P1 project was a very high feasibility with -0,33 of precision. The P2 project obtained a high feasibility with 0,38 of precision and P3 project achieved a medium feasibility with -0,21 of precision. Conclusions: This method is favorable for software projects feasibility analysis with presence of multiple experts and criteria, in environments of uncertainty. It tries heterogeneous assessments without loss of information. Their results are consistent and useful for decision makers.

Morbidity follow-up feasibility study

International Nuclear Information System (INIS)

Carpenter, M.

1988-02-01

The report reviews the available sources of data within Canada for undertaking morbidity follow-up studies to both supplement and complement studies using Canadian mortality data. Such studies would permit earlier detection and more sensitive measures of differences in risk for exposures to radiation and allow timely measures to be taken to minimize any occupational and environmental health risk to radiation workers. The technical feasibility of using these sources was reviewed using the criteria of adequate personal identifying information, automation of data records, file size and the accuracy of the morbidity diagnosis information. At the present time certain of the provincial cancer registry files meet these criteria best. A work plan was prepared suggesting a morbidity pilot study to clarify the role of occupational factors in the incidence of cancer among radiation workers using the Alberta Cancer Registry file and the National Dose Registry (NDR) file of radiation workers. For the longer term a full cohort study using the National Cancer Incidence Reporting System (NCIRS) and the NDR workers as the study population would provide information on all radiation workers on a national basis. A work plan was prepared and some initial format conversion of historical data was undertaken to begin developing the NCIRS into a data base suitable for long-term health studies

Feasible mathematics II

CERN Document Server

Remmel, Jeffrey

1995-01-01

Perspicuity is part of proof. If the process by means of which I get a result were not surveyable, I might indeed make a note that this number is what comes out - but what fact is this supposed to confirm for me? I don't know 'what is supposed to come out' . . . . 1 -L. Wittgenstein A feasible computation uses small resources on an abstract computa­ tion device, such as a 'lUring machine or boolean circuit. Feasible math­ ematics concerns the study of feasible computations, using combinatorics and logic, as well as the study of feasibly presented mathematical structures such as groups, algebras, and so on. This volume contains contributions to feasible mathematics in three areas: computational complexity theory, proof theory and algebra, with substantial overlap between different fields. In computational complexity theory, the polynomial time hierarchy is characterized without the introduction of runtime bounds by the closure of certain initial functions under safe composition, predicative recursion on nota...

Feasibility study of a contained pulsed nuclear propulsion engine

International Nuclear Information System (INIS)

Parlos, A.G.; Metzger, J.D.

1994-01-01

The result of a feasibility analysis of a contained pulsed nuclear propulsion (CPNP) engine concept utilizing the enormously dense energy generated by small nuclear detonations is presented in this article. This concept was initially proposed and studied in the 1950s and 1960s under the program name HELIOS. The current feasibility of the concept is based upon materials technology that has advanced to a state that allows the design of pressure vessels required to contain the blast associated with small nuclear detonations. The impulsive nature of the energy source provides the means for circumventing the materials thermal barriers that are inherent in steady-state nuclear propulsion concepts. The rapid energy transfer to the propellant results in high thrust levels for times less than 1 s following the detonation. The preliminary feasibility analysis using off-the-shelf materials technology appears to indicate that the CPNP concept can have thrust-to-weight ratios on the order of 1 or greater. Though the specific impulse is not a good indicator for impulsive engines, an operating-cycle averaged specific impulse of approximately 1000 or greater seconds was calculated. 16 refs

Aleutian Pribilof Islands Wind Energy Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Bruce A. Wright

2012-03-27

Under this project, the Aleutian Pribilof Islands Association (APIA) conducted wind feasibility studies for Adak, False Pass, Nikolski, Sand Point and St. George. The DOE funds were also be used to continue APIA's role as project coordinator, to expand the communication network quality between all participants and with other wind interest groups in the state and to provide continued education and training opportunities for regional participants. This DOE project began 09/01/2005. We completed the economic and technical feasibility studies for Adak. These were funded by the Alaska Energy Authority. Both wind and hydro appear to be viable renewable energy options for Adak. In False Pass the wind resource is generally good but the site has high turbulence. This would require special care with turbine selection and operations. False Pass may be more suitable for a tidal project. APIA is funded to complete a False Pass tidal feasibility study in 2012. Nikolski has superb potential for wind power development with Class 7 wind power density, moderate wind shear, bi-directional winds and low turbulence. APIA secured nearly $1M from the United States Department of Agriculture Rural Utilities Service Assistance to Rural Communities with Extremely High Energy Costs to install a 65kW wind turbine. The measured average power density and wind speed at Sand Point measured at 20m (66ft), are 424 W/m2 and 6.7 m/s (14.9 mph) respectively. Two 500kW Vestas turbines were installed and when fully integrated in 2012 are expected to provide a cost effective and clean source of electricity, reduce overall diesel fuel consumption estimated at 130,000 gallons/year and decrease air emissions associated with the consumption of diesel fuel. St. George Island has a Class 7 wind resource, which is superior for wind power development. The current strategy, led by Alaska Energy Authority, is to upgrade the St. George electrical distribution system and power plant. Avian studies in Nikolski

Feasibility study on X-ray source with pinhole imaging method

International Nuclear Information System (INIS)

Qiu Rui; Li Junli

2007-01-01

In order to verify the feasibility of study on X-ray source with pinhole imaging method, and optimize the design of X-ray pinhole imaging system, an X-ray pinhole imaging equipment was set up. The change of image due to the change of the position and intensity of X-ray source was estimated with mathematical method and validated with experiment. The results show that the change of the spot position and gray of the spot is linearly related with the change of the position and intensity of X-ray source, so it is feasible to study X-ray source with pinhole imaging method in this application. The results provide some references for the design of X-ray pinhole imaging system. (authors)

Battery energy storage market feasibility study

International Nuclear Information System (INIS)

Kraft, S.; Akhil, A.

1997-07-01

Under the sponsorship of the Department of Energy's Office of Utility Technologies, the Energy Storage Systems Analysis and Development Department at Sandia National Laboratories (SNL) contracted Frost and Sullivan to conduct a market feasibility study of energy storage systems. The study was designed specifically to quantify the energy storage market for utility applications. This study was based on the SNL Opportunities Analysis performed earlier. Many of the groups surveyed, which included electricity providers, battery energy storage vendors, regulators, consultants, and technology advocates, viewed energy storage as an important enabling technology to enable increased use of renewable energy and as a means to solve power quality and asset utilization issues. There are two versions of the document available, an expanded version (approximately 200 pages, SAND97-1275/2) and a short version (approximately 25 pages, SAND97-1275/1)

Battery energy storage market feasibility study

Energy Technology Data Exchange (ETDEWEB)

Kraft, S. [Frost and Sullivan, Mountain View, CA (United States); Akhil, A. [Sandia National Labs., Albuquerque, NM (United States). Energy Storage Systems Analysis and Development Dept.

1997-07-01

Under the sponsorship of the Department of Energy`s Office of Utility Technologies, the Energy Storage Systems Analysis and Development Department at Sandia National Laboratories (SNL) contracted Frost and Sullivan to conduct a market feasibility study of energy storage systems. The study was designed specifically to quantify the energy storage market for utility applications. This study was based on the SNL Opportunities Analysis performed earlier. Many of the groups surveyed, which included electricity providers, battery energy storage vendors, regulators, consultants, and technology advocates, viewed energy storage as an important enabling technology to enable increased use of renewable energy and as a means to solve power quality and asset utilization issues. There are two versions of the document available, an expanded version (approximately 200 pages, SAND97-1275/2) and a short version (approximately 25 pages, SAND97-1275/1).

Experiences of a feasibility study of children with albinism in Zimbabwe: a discussion paper.

Science.gov (United States)

Taylor, Julie S; Lund, Patricia

2008-08-01

Feasibility studies are often a helpful prelude to constructing fundable research proposals. Where the intended research is in a foreign country, focuses on a vulnerable population, and is aggravated by political and pragmatic challenges, feasibility studies become essential. Albinism, a genetic condition of reduced melanin synthesis, is a major public health issue in southern Africa. Whilst much is known about the health needs of children with albinism, little is understood about how to address these effectively in low income countries. Further, the child care and protection needs of children with albinism are largely unexplored. Zimbabwe's current political and economic climate presents additional challenges to research on the topic. The technical, economic, legal, collaborative, operational, schedule and political feasibilities (acronym TELCOSP) to undertaking a study on children with albinism in Zimbabwe were explored over a six week period of fieldwork in the country. Using the TELSCOSP framework allowed a deconstruction of each challenge to provide innovative solutions. The economic and legal feasibility aspects presented some difficulties that will require flexibility and perseverance to overcome. With the assistance of the local communities and people with albinism in Zimbabwe, the obstacles appear surmountable. The feasibility study provided a productive framework for addressing potential challenges in studying the needs of Zimbabwe's children living with albinism.

Implementation of enhanced recovery programme for laparoscopic distal pancreatectomy: feasibility, safety and cost analysis.

Science.gov (United States)

Richardson, John; Di Fabio, Francesco; Clarke, Hannah; Bajalan, Mohammed; Davids, Joe; Abu Hilal, Mohammed

2015-01-01

The adoption of laparoscopy for distal pancreatectomy has proven to substantially improve short-term outcomes. Stress response after major surgery can be further minimized within an enhanced recovery programme (ERP). However, data on the potential benefit of an ERP for laparoscopic distal pancreatectomy are still lacking. The aim was to assess the feasibility, safety and cost of ERP for patients undergoing laparoscopic distal pancreatectomy. This is a case-control study from a Tertiary University Hospital. Sixty-six consecutive patients who underwent laparoscopic distal pancreatectomy were analyzed. Twenty-two patients were enrolled for the ERP and compared with previous consecutive 44 patients managed traditionally (1:2 ratio). Operative details, post-operative outcome and cost analysis were compared in the two groups. Patients enrolled in the ERP had similar intraoperative blood loss (median 165 ml vs. 200 ml; p = 0.176), operation time (225 min vs. 210 min; p = 0.633), time to remove naso-gastric tube (1 vs. 1 day; p = 0.081) but significantly shorter time to mobilization (median 1 vs. 2 days; p = 0.0001), start solid diet (2 vs. 3 days; p = 0004), and pass stools (3 vs. 5 days; p = 0.002) compared to the control group. Median length of stay was significantly shorter in the ERP group (3 vs. 6 days; p pancreatectomy with significant earlier return to normal gut function, reduced length of stay and cost saving. Copyright © 2015 IAP and EPC. Published by Elsevier B.V. All rights reserved.

Economic feasibility of a solar still desalination system with enhanced productivity

KAUST Repository

Ayoub, George M.; Malaeb, Lilian

2014-01-01

amendment, in the form of a slowly-rotating hollow cylinder, was introduced within the solar still, significantly increasing the evaporative surface area. This new modified still was analyzed in terms of both operation and economic feasibility

Economic feasibility of food irradiation in the Philippines

International Nuclear Information System (INIS)

Singson, C.C.; De Guzman, Z.M.; Pasion, W.B.

1991-01-01

Food irradiation is not a new technology and is accepted in many countries. Market acceptance of irradiated foods is established and the importance of radiation to reduce post-harvest food losses, increase shelf-life and improve hygienic quality of foods has been recognized in Asia and the Pacific. Countries with strict quarantine restrictions, such as the United States and Japan, require treatment of fresh fruits and produce for insect pests disinfestation. Several studies have established the technical feasibility of using radiation to preserve some food items in the country such as mangoes, onions, garlic, black pepper, coffee, prawns and desiccated coconut. The aim of this study is to determine the feasibility of setting up an irradiation facility in the Philippines, to undertake the processing of selected food items especially those with good export potentials, to identify areas of concern vital to the success or failure of this type of undertaking and to make recommendations to enhance the viability of this project. (auth.). 13 refs.; appendices; 6 tabs

Feasibility study on the thorium fueled boiling water breeder reactor

International Nuclear Information System (INIS)

PetrusTakaki, N.

2012-01-01

The feasibility of (Th,U)O 2 fueled, boiling water breeder reactor based on conventional BWR technology has been studied. In order to determine the potential use of water cooled thorium reactor as a competitive breeder, this study evaluated criticality, breeding and void reactivity coefficient in response to changes made in MFR and fissile enrichments. The result of the study shows that while using light water as moderator, low moderator to fuel volume ratio (MFR=0.5), it was possible to breed fissile fuel in negative void reactivity condition. However the burnup value was lower than the value of the current LWR. On the other hand, heavy water cooled reactor shows relatively wider feasible breeding region, which lead into possibility of designing a core having better neutronic and economic performance than light water with negative void reactivity coefficient. (authors)

Three-dimensional dose distribution in contrast-enhanced digital mammography using Gafchromic XR-QA2 films: Feasibility study

International Nuclear Information System (INIS)

Hwang, Yi-Shuan; Lin, Yu-Ying; Cheung, Yun-Chung; Tsai, Hui-Yu

2014-01-01

This study was aimed to establish three-dimensional dose distributions for contrast-enhanced digital mammography (CEDM) using self-developed Gafchromic XR-QA2 films. Dose calibration and distribution evaluations were performed on a full-field digital mammography unit with dual energy (DE) contrast-enhanced option. Strategy for dose calibration of films in the DE mode was based on the data obtained from common target/filter/kVp combinations used clinically and the dose response model modified from Rampado's model. Dose derived from films were also verified by measured data from an ionization chamber. The average difference of dose was 8.9% in the dose range for clinical uses. Three-dimensional dose distributions were estimated using triangular acrylic phantom equipped with the mammography system. Five pieces of film sheets were separately placed between the acrylic slabs to evaluate the dose distribution at different depths. After normalizing the dose in each pixel to the maximum dose at the top-center position of the acrylic, normalized dose distribution for transverse, coronal and sagittal planes, could thus be obtained. The depth dose distribution evaluated in this study may further serve as a reference for evaluating the patient glandular dose at different depths based on the entrance exposure information. - Highlights: • CEDM techniques can enhance contrast uptake areas and suppress background tissue. • Dose for the dual-energy acquisition is about 20% higher than standard mode. • A new method is proposed to estimate the 3D dose distribution in dual-energy CEDM. • Depth of normalized dose ratio of 0.5 is less than but near 1 cm in the DE mode

Feasibility study on a cosmic-ray level gauge

International Nuclear Information System (INIS)

Matsuda, H.; Fukaya, M.; Minato, S.

1989-01-01

Cosmic-ray intensities were measured at the stairs in a subway station in Nagoya City, inside a tall concrete building and under a cylindrical water tank, to examine the feasibility of a cosmic-ray level gauge. The measured results agreed quite well with the theoretical calculations. These results show that a cosmic-ray level gauge is feasible. (author)

Feasibility studies on cogeneration from industrial wood-processing residues in Ghana

International Nuclear Information System (INIS)

Brew-Hammond, A.; Atakora, S.B.

1999-01-01

Several feasibility studies have been undertaken on cogeneration from wood-processing industrial residues in Ghana; practically all concluded that it was not economically viable because of the low tariffs for electricity in Ghana (around 3.5 US cents per kWh) at the time. Tariffs have more than doubled since September 1998 and average tariffs for industrial consumers are now around 7-8 US cents/kWh. This paper reviews earlier studies and undertakes a sensitivity analysis to determine effects of the new tariff regime and the investment costs for co-generation projects. More detailed technical and economic feasibility studies are needed to prepare the ground for an investment programme in cogeneration from wood residues. (author)

Final Report: Feasibility Study of Biomass in Snohomish County, Washington

Energy Technology Data Exchange (ETDEWEB)

Daryl Williams (Tulalip Tribes); Ray Clark (Clark Group)

2005-01-31

This report and its attachments summarizes the results of a unique tribal-farmer cooperative study to evaluate the feasibility of building one or more regional anaerobic digestion systems in Snohomish County, Washington.

Feasibility study for the redesign of MDOT's pavement management systems software.

Science.gov (United States)

2011-04-01

In August of 2006 the Mississippi Department of Transportation (MDOT) initiated State Study No. 191, entitled Feasibility : Study for the Redesign of MDOTs Pavement Management System (PMS) Software. At the initiation of this study, the : Dep...

100-KR-1 Operable Unit focused feasibility study report

International Nuclear Information System (INIS)

1994-11-01

The standard Comprehensive Environmental Response, Compensation, and Liability Act of 1980 Feasibility Study (FS) includes development and screening of alternatives and the detailed analysis of alternatives. This focused feasibility study (FFS) was conducted for the 100-KR-1 Operable Unit at the Hanford Site in southeastern Washington. The objective of this operable unit-specific FFS is to provide decision makers with sufficient information to allow appropriate and timely selection of interim remedial measures (IRM) for the five sites (116-K-1 crib, 116-K-2 trench, 116-KE-4 and 116-KW-3 retention basins, and process effluent pipelines) associated with the 100-KR-1 Operable Unit. The IRM candidate waste sites are determined in the limited field investigation. Site profiles are developed for each of these waste site. The site profiles are used in the application of the plug-in approach. The waste site either plugs into the analysis of the alternatives for the group, or deviations from the developed group alternatives are described and documented

Neutronics studies on the feasibility of developing fast breeder reactor with flexible breeding ratio

International Nuclear Information System (INIS)

Xiao Yunlong; Wu Hongchun; Zheng Youqi; Wang Kunpeng

2016-01-01

This paper investigates the feasibility of designing a flexible fast breeder reactor from the view of neutronics. It requires that the variable breeding ratio can be achieved in operating a fast reactor without significant changes of the core, including the minimum change of fuel assembly design, the minimum change of the core configuration and the same control system arrangement in the core. The sodium cooled fast reactor is investigated. Two difficulties are overcome: (1) the different excess reactivity is well controlled for different cores, especially for the one with small breeding ratio; (2) the maximum linear power density is well controlled while the breeding ratio changes. The optimizations are done to meet the requirements. The U–Pu–Zr alloy is applied to enhance the breeding. The enrichment-zoning technique with unfixed blanket assembly loading position is searched to get acceptable power distributions when the breeding ratio changes. And the control system is designed redundantly to fulfill the control needs. Then, the achieved breeding ratio can be adjusted from 1.1 to 1.4. The reactivity coefficients, temperature distributions and preliminary safety performances are evaluated to investigate the feasibility of the new concept. All the results show that it is feasible to develop the fast reactor with flexible breeding ratios, although it still highly relies on the advancement of the coolant flow control technology. (author)

A feasibility study of group cognitive rehabilitation for cancer survivors: enhancing cognitive function and quality of life.

Science.gov (United States)

Schuurs, Alana; Green, Heather J

2013-05-01

This research aimed to address the gap in evidence-based treatment available for cancer survivors who are experiencing cognitive dysfunction, through piloting a novel treatment intervention. The overall research question was whether a group cognitive rehabilitation intervention would be feasible for improving cognitive function and quality of life for people who have completed cancer treatment. Three groups of adults were recruited as follows: an intervention group of 23 cancer survivors who completed a 4-week group cognitive rehabilitation treatment, a comparison group of nine cancer survivors, and a community sample of 23 adults who had never experienced cancer. Measures of objective and subjective cognitive function, quality of life, psychosocial distress, and illness perceptions were used. The research design was non-randomised. The results indicated that the intervention was effective in improving overall cognitive function, visuospatial/constructional performance, immediate memory, and delayed memory beyond practice effects alone. It was helpful in reducing participants' perceptions of cognitive impairment and psychosocial distress, as well as promoting social functioning and understanding of cognition. The improvements were maintained at 3 months after the intervention. Participants reported a high level of satisfaction with the treatment. The results provided evidence for the feasibility of a brief group-based cognitive rehabilitation intervention to treat cognitive problems experienced by cancer survivors. Copyright © 2012 John Wiley & Sons, Ltd.

PWR decontamination feasibility study

Energy Technology Data Exchange (ETDEWEB)

Silliman, P.L.

1978-12-18

The decontamination work which has been accomplished is reviewed and it is concluded that it is worthwhile to investigate further four methods for decontamination for future demonstration. These are: dilute chemical; single stage strong chemical; redox processes; and redox/chemical in combination. Laboratory work is recommended to define the agents and processes for demonstration and to determine the effect of the solvents on PWR materials. The feasibility of Indian Point 1 for decontamination demonstrations is discussed, and it is shown that the system components of Indian Point 1 are well suited for use in demonstrations.

PWR decontamination feasibility study

International Nuclear Information System (INIS)

Silliman, P.L.

1978-01-01

The decontamination work which has been accomplished is reviewed and it is concluded that it is worthwhile to investigate further four methods for decontamination for future demonstration. These are: dilute chemical; single stage strong chemical; redox processes; and redox/chemical in combination. Laboratory work is recommended to define the agents and processes for demonstration and to determine the effect of the solvents on PWR materials. The feasibility of Indian Point 1 for decontamination demonstrations is discussed, and it is shown that the system components of Indian Point 1 are well suited for use in demonstrations

Moroccan wind farm potential feasibility. Case study

International Nuclear Information System (INIS)

Nouri, Abdellatif; Ait Babram, Mohamed; Elwarraki, Elmostafa; Enzili, Mustapha

2016-01-01

Highlights: • A new methodology for the technical feasibility of wind farm potentials is proposed. • The wind resources of two different sites in Morocco are compared. • Comparison between short and long term data using multivariate analysis is made. • Geographic information system implementation. • A 10 MW wind farm is designed and optimized. - Abstract: The subject of this paper is the elaboration of a methodology to study the technical feasibility of a wind farm potential. The implementation of this methodology allows a comparison between the wind resources of two different sites in Morocco. One site is located in the region of Essaouira, whereas the other one is located in the region of Safi. The comparison is based on real wind data collected from two masts at the heights of 30, 50, and 60 m. Each of the masts is installed at one of the mentioned potential sites over a fixed time period, lasting fifteen months for the first site, and eight months for the second one. The aim is the determination of the most applicable site presenting a good potential for a statistical study in order to predict long-term wind behaviors. Thus, the geographical situation study of the chosen site including topography, roughness and obstacles, is carried out. Furthermore, the wind resource using data, generated by the measuring masts, is evaluated. Finally, the areas which present great wind potential are located and the wind farm turbine locations are optimized by using the WAsP software.

Feasibility of multi-sector policy measures that create activity-friendly environments for children: results of a Delphi study

Directory of Open Access Journals (Sweden)

Aarts Marie-Jeanne

2011-12-01

Full Text Available Abstract Background Although multi-sector policy is a promising strategy to create environments that stimulate physical activity among children, little is known about the feasibility of such a multi-sector policy approach. The aims of this study were: to identify a set of tangible (multi-sector policy measures at the local level that address environmental characteristics related to physical activity among children; and to assess the feasibility of these measures, as perceived by local policy makers. Methods In four Dutch municipalities, a Delphi study was conducted among local policy makers of different policy sectors (public health, sports, youth and education, spatial planning/public space, traffic and transportation, and safety. In the first Delphi round, respondents generated a list of possible policy measures addressing three environmental correlates of physical activity among children (social cohesion, accessibility of facilities, and traffic safety. In the second Delphi round, policy makers weighted different feasibility aspects (political feasibility, cultural/community acceptability, technical feasibility, cost feasibility, and legal feasibility and assessed the feasibility of the policy measures derived from the first round. The third Delphi round was aimed at reaching consensus by feedback of group results. Finally, one overall feasibility score was calculated for each policy measure. Results Cultural/community acceptability, political feasibility, and cost feasibility were considered most important feasibility aspects. The Delphi studies yielded 16 feasible policy measures aimed at physical and social environmental correlates of physical activity among children. Less drastic policy measures were considered more feasible, whereas environmental policy measures were considered less feasible. Conclusions This study showed that the Delphi technique can be a useful tool in reaching consensus about feasible multi-sector policy measures. The

Feasibility study on the development of advanced LWR fuel technology

International Nuclear Information System (INIS)

Jung, Youn Ho; Sohn, D. S.; Jeong, Y. H.; Song, K. W.; Song, K. N.; Chun, T. H.; Bang, J. G.; Bae, K. K.; Kim, D. H. and others.

1997-07-01

Worldwide R and D trends related to core technology of LWR fuels and status of patents have been surveyed for the feasibility study. In addition, various fuel cycle schemes have been studied to establish the target performance parameters. For the development of cladding material, establishment of long-term research plan for alloy development and optimization of melting process and manufacturing technology were conducted. A work which could characterize the effect of sintering additives on the microstructure of UO 2 pellet has been experimentally undertaken, and major sintering variables and their ranges have been found in the sintering process of UO 2 -Gd 2 O 3 burnable absorber pellet. The analysis of state of the art technology related to flow mixing device for spacer grid and debris filtering device for bottom nozzle and the investigation of the physical phenomena related to CHF enhancement and the establishment of the data base for thermal-hydraulic performance tests has been done in this study. In addition, survey on the documents of the up-to-date PWR fuel assemblies developed by foreign vendors have been carried out to understand their R and D trends and establish the direction of R and D for these structural components. And, to set the performance target of the new fuel, to be developed, fuel burnup and economy under the extended fuel cycle length scheme were estimated. A preliminary study on the failure mechanism of CANDU fuel, key technology and advanced coating has been performed. (author). 190 refs., 31 tabs., 129 figs

Feasibility study on the development of advanced LWR fuel technology

Energy Technology Data Exchange (ETDEWEB)

Jung, Youn Ho; Sohn, D. S.; Jeong, Y. H.; Song, K. W.; Song, K. N.; Chun, T. H.; Bang, J. G.; Bae, K. K.; Kim, D. H. and others

1997-07-01

Worldwide R and D trends related to core technology of LWR fuels and status of patents have been surveyed for the feasibility study. In addition, various fuel cycle schemes have been studied to establish the target performance parameters. For the development of cladding material, establishment of long-term research plan for alloy development and optimization of melting process and manufacturing technology were conducted. A work which could characterize the effect of sintering additives on the microstructure of UO{sub 2} pellet has been experimentally undertaken, and major sintering variables and their ranges have been found in the sintering process of UO{sub 2}-Gd{sub 2}O{sub 3} burnable absorber pellet. The analysis of state of the art technology related to flow mixing device for spacer grid and debris filtering device for bottom nozzle and the investigation of the physical phenomena related to CHF enhancement and the establishment of the data base for thermal-hydraulic performance tests has been done in this study. In addition, survey on the documents of the up-to-date PWR fuel assemblies developed by foreign vendors have been carried out to understand their R and D trends and establish the direction of R and D for these structural components. And, to set the performance target of the new fuel, to be developed, fuel burnup and economy under the extended fuel cycle length scheme were estimated. A preliminary study on the failure mechanism of CANDU fuel, key technology and advanced coating has been performed. (author). 190 refs., 31 tabs., 129 figs.

Symplicity multi-electrode radiofrequency renal denervation system feasibility study.

Science.gov (United States)

Whitbourn, Robert; Harding, Scott A; Walton, Antony

2015-05-01

The aim of this study was to test the safety and performance of the Symplicity™ multi-electrode radio-frequency renal denervation system which was designed to reduce procedure time during renal denervation. The multi-electrode radiofrequency renal denervation system feasibility study is a prospective, non-randomised, open label, feasibility study that enrolled 50 subjects with hypertension. The study utilises a new renal denervation catheter which contains an array of four electrodes mounted in a helical configuration at 90 degrees from each other to deliver radiofrequency energy simultaneously to all four renal artery quadrants for 60 seconds. The protocol specified one renal denervation treatment towards the distal end of each main renal artery with radiofrequency energy delivered for 60 seconds per treatment. Total treatment time for both renal arteries was two minutes. The 12-month change in office systolic blood pressure (SBP) and 24-hour SBP was -19.2±25.2 mmHg, prenal artery stenosis or hypertensive emergencies occurred. The Symplicity multi-electrode radiofrequency renal denervation system was associated with a significant reduction in SBP at 12 months and minimal complications whilst it also reduced procedure time. NCT01699529.

Prospective interepisodal mood monitoring in patients with affective disorders: a feasibility study

Directory of Open Access Journals (Sweden)

Van der Watt ASJ

2018-02-01

Full Text Available Alberta SJ Van der Watt,1 Alexandra PSP Suryapranata,2 Soraya Seedat1 1Department of Psychiatry, Stellenbosch University, Cape Town, South Africa; 2Internal Medicine, Onze Lieve Vrouwe Gasthuis West, Amsterdam, the Netherlands Objectives: Our primary objective was to assess the feasibility of interepisodal telephonic mood monitoring in patients with affective disorders in a low-resource setting. Secondary objectives included gathering data on longitudinal mood trajectories and assessing patient acceptance of mood monitoring. Methods: Inpatients with a primary mood or anxiety disorder were recruited predischarge. Assessment at intake included demographic information, the Life Events Checklist, and the Childhood Trauma Questionnaire. Participants telephonically completed the Altman Self-Rating Mania Scale (ASRM and Quick Inventory of Depressive Symptomatology (QIDS, weekly, for 26 weeks. Units of alcohol consumed and life events were recorded. Semi-structured interviews were conducted midway through the mood monitoring protocol. Results: Of the 61 eligible participants (77% female; mean age =35.3 years, 28 completed 26 weeks of telephonic mood monitoring. Thirty-three participants (54.1% withdrew prematurely or were lost to follow-up. Males were more likely to terminate study participation prematurely. Despite the significant decline in depression scores over 26 weeks, participants endorsed persistent mild-to-moderate depressive symptoms. Statistically, participants who were married/in a relationship had higher mean depression scores throughout the study compared to participants who were single. Throughout the study, ASRM scores were not indicative of significant mania. Suicidality (as measured by QIDS item 12 was highest at Week 3 and Week 12 postdischarge for those who completed 26 weeks of monitoring. Conclusion: Despite the high attrition rate, interepisodal telephonic mood monitoring was deemed to be feasible and it can provide useful

Code of Conduct for wind-power projects - Feasibility study

International Nuclear Information System (INIS)

Strub, P.; Ziegler, Ch.

2009-02-01

This final report deals with the results of a feasibility study concerning the development of a Code of Conduct for wind-power projects. The aim is to strengthen the acceptance of wind-power by the general public. The necessity of new, voluntary market instruments is discussed. The urgency of development in this area is quoted as being high, and the authors consider the feasibility of the definition of a code of conduct as being proven. The code of conduct can, according to the authors, be of use at various levels but primarily in project development. Further free-enterprise instruments are also suggested that should help support socially compatible and successful market development. It is noted that the predominant portion of those questioned are prepared to co-operate in further work on the subject

MRS transfer facility feasibility study

International Nuclear Information System (INIS)

Jowdy, A.K.; Smith, R.I.

1990-12-01

Under contract to the US Department of Energy, Parsons was requested to evaluate the feasibility of building a simple hot cell (waste handling) transfer facility at the Monitored Retrievable Storage (MRS) site to facilitate acceptance of spent fuel into the Federal Waste Management System starting in early 1998. The Transfer Facility was intended to provide a receiving and transfer to storage capability at a relatively low throughput rate (approximately 500 MTU/yr) and to provide the recovery capability needed on the site in the event of a transport or storage cask seal failure during a period of about two years while the larger Spent Fuel Handling Building (SFHB) was being completed. Although the original study basis postulated an incremental addition to the larger, previously considered MRS configurations, study results show that the Transfer Facility may be capable of receiving and storing spent fuel at annual rates of 3000 MTU/yr or more, making a larger fuel handling structure unnecessary. In addition, the study analyses showed that the Transfer Facility could be constructed and put into service in 15--17 months and would cost less than the previous configurations. 2 figs., 2 tabs

What is a pilot or feasibility study? A review of current practice and editorial policy

Directory of Open Access Journals (Sweden)

Cooper Cindy L

2010-07-01

Full Text Available Abstract Background In 2004, a review of pilot studies published in seven major medical journals during 2000-01 recommended that the statistical analysis of such studies should be either mainly descriptive or focus on sample size estimation, while results from hypothesis testing must be interpreted with caution. We revisited these journals to see whether the subsequent recommendations have changed the practice of reporting pilot studies. We also conducted a survey to identify the methodological components in registered research studies which are described as 'pilot' or 'feasibility' studies. We extended this survey to grant-awarding bodies and editors of medical journals to discover their policies regarding the function and reporting of pilot studies. Methods Papers from 2007-08 in seven medical journals were screened to retrieve published pilot studies. Reports of registered and completed studies on the UK Clinical Research Network (UKCRN Portfolio database were retrieved and scrutinized. Guidance on the conduct and reporting of pilot studies was retrieved from the websites of three grant giving bodies and seven journal editors were canvassed. Results 54 pilot or feasibility studies published in 2007-8 were found, of which 26 (48% were pilot studies of interventions and the remainder feasibility studies. The majority incorporated hypothesis-testing (81%, a control arm (69% and a randomization procedure (62%. Most (81% pointed towards the need for further research. Only 8 out of 90 pilot studies identified by the earlier review led to subsequent main studies. Twelve studies which were interventional pilot/feasibility studies and which included testing of some component of the research process were identified through the UKCRN Portfolio database. There was no clear distinction in use of the terms 'pilot' and 'feasibility'. Five journal editors replied to our entreaty. In general they were loathe to publish studies described as 'pilot'. Conclusion

Feasibility study for the installation of photovoltaic cladding on the Shirehall, Shrewsbury

Energy Technology Data Exchange (ETDEWEB)

NONE

1999-10-01

The study has shown that it is technically feasible to overcome the problems with the existing mosaic cladding with the insulation of PV rainscreen cladding incorporating thermal insulation and to provide an acceptable, possibly enhanced, visual appearance. Panels which match the PV panels but provide no electrical output would be required in areas where PV panels would be inappropriate. This arrangement results in additional costs. The PV panels would produce an estimated 321,200 kWh/year of electricity and the improved insulation provided with the system would save an estimated 388,800 kWh/year of gas for heating giving savings of about UK pounds 19,000/year. The costs of installing the rainscreen cladding over and above that required for the straightforward replacement of the existing mosaic tiles would be approximately UK pounds 3 million. The savings in the use of electricity and gas arising from the use of the PV rainscreen incorporating thermal insulation are unlikely to be sufficient to satisfy the normal criteria for the provision of the capital investment required. (author)

CONTRACT Study - CONservative TReatment of Appendicitis in Children (feasibility): study protocol for a randomised controlled Trial.

Science.gov (United States)

Hutchings, Natalie; Wood, Wendy; Reading, Isabel; Walker, Erin; Blazeby, Jane M; Van't Hoff, William; Young, Bridget; Crawley, Esther M; Eaton, Simon; Chorozoglou, Maria; Sherratt, Frances C; Beasant, Lucy; Corbett, Harriet; Stanton, Michael P; Grist, Simon; Dixon, Elizabeth; Hall, Nigel J

2018-03-02

Currently, the routine treatment for acute appendicitis in the United Kingdom is an appendicectomy. However, there is increasing scientific interest and research into non-operative treatment of appendicitis in adults and children. While a number of studies have investigated non-operative treatment of appendicitis in adults, this research cannot be applied to the paediatric population. Ultimately, we aim to perform a UK-based multicentre randomised controlled trial (RCT) to test the clinical and cost effectiveness of non-operative treatment of acute uncomplicated appendicitis in children, as compared with appendicectomy. First, we will undertake a feasibility study to assess the feasibility of performing such a trial. The study involves a feasibility RCT with a nested qualitative research to optimise recruitment as well as a health economic substudy. Children (aged 4-15 years inclusive) diagnosed with acute uncomplicated appendicitis that would normally be treated with an appendicectomy are eligible for the RCT. Exclusion criteria include clinical/radiological suspicion of perforated appendicitis, appendix mass or previous non-operative treatment of appendicitis. Participants will be randomised into one of two arms. Participants in the intervention arm are treated with antibiotics and regular clinical assessment to ensure clinical improvement. Participants in the control arm will receive appendicectomy. Randomisation will be minimised by age, sex, duration of symptoms and centre. Children and families who are approached for the RCT will be invited to participate in the embedded qualitative substudy, which includes recording of recruitment consultants and subsequent interviews with participants and non-participants and their families and recruiters. Analyses of these will inform interventions to optimise recruitment. The main study outcomes include recruitment rate (primary outcome), identification of strategies to optimise recruitment, performance of trial treatment

Feasibility studies for the Forward Spectrometer

International Nuclear Information System (INIS)

Biernat, Jacek

2015-01-01

The Forward Spectrometer designed for the P-barANDA detector will consist of many different detector systems allowing for precise track reconstruction and particle identification. Feasibility studies for Forward Spectrometer done by means of specific reactions will be presented. In the first part of the paper, results of simulations focussing on rate estimates of the tracking stations based on straw tubes will be presented. Next, the importance of the Forward Tracker will be demonstrated through the reconstruction of the ψ(4040) → DD-bar decay. Finally, results from the analysis of the experimental data collected with a straw tube prototype designed and constructed at the Research Center in Juelich will be discussed. (paper)

Feasibility Study for the Development of SCWR

International Nuclear Information System (INIS)

Bae, Y. Y.; Kim, H. Y.; Cho, B. H.

2010-04-01

- As a result of feasibility study, following conclusions were drawn: · SCWR can be a strong candidate to a large-scale electric power production plant. · Infra-structure for development of an economic and safe SCWR is well established. · It is recommended to focus on the university-level fundamental research along with an international collaboration, for the time being. - The supercritical heat transfer research produced a lot of database on the small tubes and annular channels. - Among the candidate materials such as T92, Incolloy 800, MA956, ODS showed the superior characteristics

Feasibility study on plan to utilize livestock excreta for bio-gas in Miyagi Village (Gunma Prefecture). Investigations on projects including district new energy vision establishment in fiscal 2000, and on feasibility for commercialization; Miyagimura chikusan haisetsubutsu bio gas ka energy riyo keikaku feasibility study. 2000 nendo chiiki shin energy vision sakutei nado jigyo, jigyoka feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-02-01

With objectives to utilize energy available from livestock excreta, and to properly treat the livestock excreta, a feasibility study was performed on a plan to utilize livestock excreta for bio-gas. The system to be developed is a livestock wastes treatment system to utilize gas generated by efficiently fermenting the excreta as fuel, and residual sludge solids as compost. The activity achievements were put into order by the following nine items: 1) purpose of the feasibility study, 2) method for the feasibility study, 3) the situation where the livestock industry and the hog raising industry were selected as the object of the investigation, 4) properties of hog excreta, characteristics in urine foul water treatment, technologies for urine foul water treatment (biological treatment), 5) bio-gasification of livestock wastes, 6) the basic conditions for investigating the demonstration bio-bas plants, 7) proposals and standard cases of the demonstration bio gas plants, 8) discussions and positioning of the basic system for the demonstration bio gas plants, and 9) conclusion. (NEDO)

A feasibility study of bridge deck deicing using geothermal energy.

Science.gov (United States)

2015-04-01

In this study, we investigated the feasibility of a ground-coupled system that utilizes heat energy harvested from the ground for : deicing of bridge decks. Heat exchange is performed using circulation loops integrated into the deep foundations suppo...

Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD

International Nuclear Information System (INIS)

Morgan, Alexandra R.; Parker, Geoff J.M.; Roberts, Caleb; Buonaccorsi, Giovanni A.; Maguire, Niall C.; Hubbard Cristinacce, Penny L.; Singh, Dave; Vestbo, Jørgen; Bjermer, Leif; Jögi, Jonas; Taib, Ziad; Sarv, Janeli; Bruijnzeel, Piet L.B.; Olsson, Lars E.; Bondesson, Eva; Nihlén, Ulf; McGrath, Deirdre M.; Young, Simon S.

2014-01-01

Highlights: • We investigate physiologic response to standard COPD treatment regimes using OE-MRI. • We assess the potential role of OE-MRI in future drug development studies. • In COPD, OE-MRI parameters showed response to single-dose formoterol. • OE-MRI parameters showed response to 8-week formoterol/budesonide treatment. • OE-MRI measurements are feasible in a small-scale multi-center trial setting. - Abstract: Objectives: Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests. Materials and methods: COPD patients (n = 40), mean FEV 1 58% predicted normal, received single-dose inhaled formoterol 9 μg, or placebo, followed by 8 weeks treatment bid with a combination of budesonide and formoterol Turbuhaler ® 320/9 μg or formoterol Turbuhaler ® . OE-MRI biomarkers were obtained, as well as X-ray computed tomography (CT) biomarkers and pulmonary function tests, in a two-center study. An ANCOVA statistical model was used to assess effect size of intervention measurable in OE-MRI parameters of lung function. Results: OE-MRI data were successfully acquired at both study sites. 8-week treatment with budesonide/formoterol significantly decreased lung wash-out time by 31% (p < 0.01), decreased the change in lung oxygen level upon breathing pure oxygen by 13% (p < 0.05) and increased oxygen extraction from the lung by 58% (p < 0.01). Single-dose formoterol increased both lung wash-out time (+47%, p < 0.05) and lung oxygenation time (+47%, p < 0.05). FEV 1 was improved by single-dose formoterol (+12%, p < 0.001) and 8 weeks of budesonide/formoterol (+ 18%, p < 0.001), consistent with published studies. Conclusions: In COPD

Feasibility assessment of using oxygen-enhanced magnetic resonance imaging for evaluating the effect of pharmacological treatment in COPD

Energy Technology Data Exchange (ETDEWEB)

Morgan, Alexandra R., E-mail: alex.morgan@bioxydyn.com [Bioxydyn Ltd, Manchester (United Kingdom); Centre for Imaging Sciences and Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester (United Kingdom); Parker, Geoff J.M.; Roberts, Caleb [Bioxydyn Ltd, Manchester (United Kingdom); Centre for Imaging Sciences and Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester (United Kingdom); Buonaccorsi, Giovanni A.; Maguire, Niall C. [Bioxydyn Ltd, Manchester (United Kingdom); Hubbard Cristinacce, Penny L. [Centre for Imaging Sciences and Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester (United Kingdom); Singh, Dave; Vestbo, Jørgen [University of Manchester, Medicines Evaluation Unit, Manchester Academic Health Sciences Centre, University Hospital of South Manchester, Manchester (United Kingdom); Bjermer, Leif [Department of Respiratory Medicine and Allergology, Skåne University Hospital, Lund (Sweden); Jögi, Jonas [Department of Clinical Physiology, Skåne University Hospital and Lund University, Lund (Sweden); Taib, Ziad; Sarv, Janeli; Bruijnzeel, Piet L.B.; Olsson, Lars E.; Bondesson, Eva [AstraZeneca R and D, Mölndal (Sweden); Nihlén, Ulf [Department of Respiratory Medicine and Allergology, Skåne University Hospital, Lund (Sweden); AstraZeneca R and D, Mölndal (Sweden); McGrath, Deirdre M. [Centre for Imaging Sciences and Biomedical Imaging Institute, Manchester Academic Health Sciences Centre, University of Manchester, Manchester (United Kingdom); Young, Simon S. [AstraZeneca R and D, Alderley Park (United Kingdom); and others

2014-11-15

Highlights: • We investigate physiologic response to standard COPD treatment regimes using OE-MRI. • We assess the potential role of OE-MRI in future drug development studies. • In COPD, OE-MRI parameters showed response to single-dose formoterol. • OE-MRI parameters showed response to 8-week formoterol/budesonide treatment. • OE-MRI measurements are feasible in a small-scale multi-center trial setting. - Abstract: Objectives: Oxygen-enhanced MRI (OE-MRI) biomarkers have potential value in assessment of COPD, but need further evaluation before treatment-induced changes can be interpreted. The objective was to evaluate how OE-MRI parameters of regional ventilation and oxygen uptake respond to standard pharmacological interventions in COPD, and how the response compares to that of gold standard pulmonary function tests. Materials and methods: COPD patients (n = 40), mean FEV{sub 1} 58% predicted normal, received single-dose inhaled formoterol 9 μg, or placebo, followed by 8 weeks treatment bid with a combination of budesonide and formoterol Turbuhaler{sup ®} 320/9 μg or formoterol Turbuhaler{sup ®}. OE-MRI biomarkers were obtained, as well as X-ray computed tomography (CT) biomarkers and pulmonary function tests, in a two-center study. An ANCOVA statistical model was used to assess effect size of intervention measurable in OE-MRI parameters of lung function. Results: OE-MRI data were successfully acquired at both study sites. 8-week treatment with budesonide/formoterol significantly decreased lung wash-out time by 31% (p < 0.01), decreased the change in lung oxygen level upon breathing pure oxygen by 13% (p < 0.05) and increased oxygen extraction from the lung by 58% (p < 0.01). Single-dose formoterol increased both lung wash-out time (+47%, p < 0.05) and lung oxygenation time (+47%, p < 0.05). FEV{sub 1} was improved by single-dose formoterol (+12%, p < 0.001) and 8 weeks of budesonide/formoterol (+ 18%, p < 0.001), consistent with published studies

A feasibility study of educational tools for osteomalacia.

Science.gov (United States)

Waxman, R; Adebajo, A; Robinson, S; Walker, D; Johnson, M; Rahman, A; Samanta, A; Kumar, K; Raza, K; Helliwell, P

2017-03-01

Many people in the UK, particularly people of South Asian origin, are advised to supplement their vitamin D intake, yet most do not. This suggests an unmet educational need. The osteomalacia mind map was developed to meet this need. The mind map contains culturally sensitive images, translated into Urdu and made interactive on a DVD. This study explores the feasibility of a randomised controlled study to measure the effect of education on improving vitamin D knowledge and adherence. This was a pilot and feasibility study. Cluster randomisation was used to avoid inter person contamination. Two South Asian women's groups were recruited to receive information about osteomalacia either by interactive DVD or an Arthritis Research UK leaflet. Knowledge and compliance were tested before and after the educational interventions via a knowledge questionnaire and the measurement of vitamin D and parathormone levels. The groups were found to be mismatched for knowledge, educational attainment and language at baseline. There were also organisational difficulties and possible confounding due to different tutors and translators. The DVD group had high knowledge at baseline which did not improve. The leaflet group had low knowledge at baseline that did improve. The DVD group had lower parathormone which did not change. The leaflet group had an increase in vitamin D but parathormone remained high. Performing a randomised study with this population utilising an educational intervention was difficult to execute. If cluster randomisation is used, extreme care must be taken to match the groups at baseline.

Feasibility study of electric motors constructed with high temperature superconducting materials

International Nuclear Information System (INIS)

Jordan, H.E.

1989-01-01

The potential application of high temperature superconducting (HTSC) materials to electric motors is discussed. The specific application area of motors in electric power generating stations has been selected and a feasible study has been initiated on the use of HTSC materials in the design of motors for this application. A progress report on this feasibility study is presented. Technical challenges in both the development of HTSC wire and the design of a motor to utilize this wire are discussed. Finally, the results of design calculations comparing a superconducting motor with one of conventional design are presented assuming that success can be achieved in overcoming the technical problems which must be resolved to produce a high performance HTSC wire

Feasibility studies for decommissioning

International Nuclear Information System (INIS)

Hladky, E.

2000-01-01

In this presentation author deals with planning of decommission of the NPPs A1, V1 and V2 Bohunice and Mochovce. It was concluded that: Used model for decommissioning parameters assessment has been suitable for elaboration of initial decommissioning plans (feasibility studies); Basic assessment of main decommissioning parameters and basic comparison of various decommissioning options have been possible; Improvement of the model and corresponding software is desirable and works on software improvement began one year ago; V1-NPP initial decommissioning plan should be actualized, because initial decommissioning plan does not correspond by its content and structure to requirements of Act No. 130/98 and Nuclear Regulatory Authority Degree No. 246/99; Strategy of radioactive wastes treatment and conditioning together with technical provisions at Jaslovske Bohunice site was changed in comparison with the assumptions in 1991-92; Considered V1 NPP decommissioning options are necessary to be re-evaluated in accordance with latest development of knowledge and approaches to NPP decommissioning in the world; Specific unit costs are substantially and differentially changed in comparison with the assumptions in 1991-92; Necessity to take into account technical changes resulted from V1 NPP reconstruction. (author)

A feasibility study for the development of an SCWR in Korea

International Nuclear Information System (INIS)

Hong, Sung-Yull; Kim, Yong-Bae; Bae, Seong-Man; Lee, Kwangho; Kim, Junhyung; Bae, Yoon-Yeong

2008-01-01

Korea is participating in international collaboration activities since the selection of supercritical water-cooled reactor (SCWR) as one of the viable candidates for Generation IV reactor systems in 2002. The SCWR has been selected by Generation IV International Forum (GIF) since it is a very feasible candidate reactor system for a large-scale electricity production in commercially viable manner. However, the level of Korean participation is still limited to several key areas and the decision-making on whether going into full-scale research is yet to be made. In three circumstances it has been decided to launch a feasibility study in March 2007 to assess the domestic capability and resources as well as economics for development of an SCWR and to identify the required research areas. This paper introduces the project named 'A feasibility study for the development of an SCWR in Korea', which is sponsored by MEST (Ministry of Education, Science and Technology) in Korea. The main purpose of this study is to provide a basis for establishing a government policy in consideration of the unique domestic environment for SCWR development. This study includes three different areas of evaluation aspect, i.e., policy and environment, technology and safety, and economics. In policy and environment aspects, the needs of SCWR development is evaluated in terms of future electricity demand, reactor type strategy, fuel cycle policy, and available infrastructure in Korea, etc. In technology and safety aspects, evaluation is performed to identify the most optimum way of SCWR R and D strategy and several fundamental studies including heat transfer, code developments, and materials are performed in parallel. Finally, in economic aspect, the economic feasibility of SCWR development is assessed in comparison with the Korean nuclear power plants OPR1000 and APR1400 and other comparable overseas reactors. This study will be finished by 2010 and the results of the assessment will become a

Transvaginal uterosacral ligament hysteropexy: a retrospective feasibility study.

Science.gov (United States)

Milani, Rodolfo; Frigerio, Matteo; Manodoro, Stefano; Cola, Alice; Spelzini, Federico

2017-01-01

Uterine-sparing procedures could be attractive in patients concerned about preservation of fertility and change in corporeal image and sexuality. Transvaginal uterosacral hysteropexy can provide an alternative mesh-free technique for uterine suspension. This study aimed to evaluate the feasibility of transvaginal uterine suspension to uterosacral ligaments in terms of operative data, complications, midterm efficacy, and patient satisfaction. This retrospective study analyzed the first 20 cases of transvaginal hysteropexy through bilateral high uterosacral ligaments (modified Shull technique) performed in our Institution. Mean follow-up was 33.2 months. The procedure was performed in 84 ± 19 min ,and blood loss was 228 ± 139 ml. Three mild complications (15 %) were observed. Recurrence [Pelvic Organ Prolapse Quantification system (POP-Q) stage ≥ II was observed in five patients (25 %), and three of them (15 %) required reintervention. Mean Patient Global Impression of Improvement score was "much improved." Two woman (40 %) who had not fulfilled their childbearing desire obtained a pregnancy. Both underwent elective caesarean section at term. Transvaginal uterosacral hysteropexy appears a feasible mesh-free technique for apical support. This procedure can be indicated in women with the desire of preserving fertility or who prefer a uterine-sparing surgical option.

7 CFR 1980.442 - Feasibility studies.

Science.gov (United States)

2010-01-01

... management, nature and extent of market area, marketing plans for sale of projected output, extent of... Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS...) PROGRAM REGULATIONS (CONTINUED) GENERAL Business and Industrial Loan Program § 1980.442 Feasibility...

100-HR-2 Operable Unit Focused Feasibility study report

International Nuclear Information System (INIS)

1995-01-01

The standard Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA) Feasibility Study (FS) includes development and screening of alternatives (Phases 1 and 2) and the detailed analysis of alternatives (Phase 3). This focused feasibility study (FFS) was conducted for the 100-HR-2 Operable Unit (OU) at the Hanford Site in southeastern Washington. This FFS constitutes the Phase 3 portion of the FS process for the remedial alternatives initially developed and screened in the 100 Area Feasibility Study Phases 1 and 2 (DOE-RL 1993a). The objective of this OU-specific FFS is to provide decision makers with sufficient information to allow appropriate and timely selection of interim remedial measures (IRM) for the seven IRM candidate sites associated with the 100-HR-2 OU. The IRM candidate waste sites identified in Table ES-1 are determined in the limited field investigation (DOE-RL 1994b). Site profiles are developed for each of these waste sites. The site profiles are used in the application of the plug-in approach. The waste site either plugs into the analysis of the alternatives for the group, or deviations from the developed group alternatives are described and documented. A summary for the 100-HR-2 IRM candidate waste site is as follows: none of the waste sites require additional alternative development. six of the seven waste sites directly plug into the waste site group alternatives. The site-specific detailed analysis is conducted, referencing the waste site group analysis as appropriate. A waste site detailed analysis summary is presented in Table ES-1.A comparative analysis of remedial alternatives is presented for each waste site. A summary of the comparative analysis is presented in Table ES-2

The Pocos de Caldas project feasibility study: 1986-7

International Nuclear Information System (INIS)

Smellie, J.A.T.; Chapman, N.A.; Franca, E.P.

1987-01-01

This paper presents feasibility studies to investigate the uranium, thorium and rare earth deposits, in Morro do Ferro and the uranium mine in Osamu Utsumi, Brazil, as natural analogues to link rock geochemistry and hydrogeological systems to assess radionuclide mobility. Ore samples were analysed to obtain uranium concentrations and hydraulic tests were carried out. (UK)

Feasibility study on fission moly target development

International Nuclear Information System (INIS)

Kim, Byung Ku; Kim, Seong Nyun; Shon, Dong Seong; Choi, Chang Beom; Lee, Jae Kuk; Park, Jin Ho; Jeong, Won Myung; Jeon, Kwan Sik; You, Jae Hyung; Kang, Kyung Chul; Ahn, Jong Hwan; Ju, Po Kuk

1996-01-01

A multi-purpose research reactor, HANARO has been operated on the beginning of 1995 and can be utilized for production of various radioisotopes. And a R and D program for fission Mo production was established, and the technical and economical feasibility study has been performed for fission Mo production in Korea. In this study the process for fission Mo production was recommended as follows; 1. Target : UO 2 of annulus type. 2. Separation and purification : Nitric acid dissolution → Alumina adsorption → Benzoin oxime precipitation → Alumina adsorption. And more desirable plan for steady supply of fission Mo were suggested in following viewpoints; 1. Technical collaboration with foreign company. 2. Backup supply system. 3. Marketing arrangement. (Author)

Feasibility Study for Paragon - Bisti Solar Ranch

Energy Technology Data Exchange (ETDEWEB)

Benally, Thomas [Navajo Hopi Land Commission Office (NHLCO), Window Rock, AZ (United States)

2015-06-01

The Navajo Hopi Land Commission Office (NHLCO) and Navajo Nation (NN) plan to develop renewable energy (RE) projects on the Paragon-Bisti Ranch (PBR) lands, set aside under the Navajo Hopi Land Settlement Act (NHLSA) for the benefit of Relocatees. This feasibility study (FS), which was funded under a grant from DOE’s Tribal Energy Program (TEP), was prepared in order to explore the development of the 22,000-acre PBR in northwestern New Mexico for solar energy facilities. Topics covered include: • Site Selection • Analysis of RE, and a Preliminary Design • Transmission, Interconnection Concerns and Export Markets • Financial and Economic Analysis • Environmental Study • Socioeconomic and Cultural Factors • Next Steps.

Cadaveric surgery in core gynaecology training: a feasibility study.

Science.gov (United States)

Lim, Chou Phay; Roberts, Mark; Chalhoub, Tony; Waugh, Jason; Delegate, Laura

2018-01-01

Fresh frozen cadaver training has been proposed as a better model than virtual reality simulators in laparoscopy training. We aimed to explore the relationship between cadaveric surgical training and increased surgical confidence.To determine feasibility, we devised two 1-day cadaveric surgical training days targeted at trainees in obstetrics and gynaecology. Seven defined surgical skills were covered during the course of the day. The relationship between surgical training and surgical confidence was explored using both quantitative (confidence scores) and qualitative tools (questionnaires). Participants rated a consistent improvement in their level of confidence after the training. They universally found the experience positive and three overarching themes emerged from the qualitative analysis including self-concept, social persuasion and stability of task. It is pragmatically feasible to provide procedure-specific cadaveric surgical training alongside supervised clinical training. This small, non-generalisable study suggests that cadaveric training may contribute to an increase in surgical self-confidence and efficacy. This will form the basis of a larger study and needs to be explored in more depth with a larger population.

Feasibility study for the European Reliability Data System (ERDS)

International Nuclear Information System (INIS)

Mancini, G.

1980-01-01

In the framework of the Reactor Safety Programme of the Commission of the European Communities, the JRC - Ispra Establishment has performed a feasibility study for an integrated European Reliability Data System, the aim of which is the collection and organization of information related to the operation of LWRs with regard to component and systems behaviour, abnormal occurrences, outages, etc. Component Event Data Bank (CEGB), Abnormal Occurrences Reporting System, Generic Reliability Parameter Data Bank, Operating Unit Status Reports and the main activities carried out during the last two years are described. The most important achievements are briefly reported, such as: Reference Classification for Systems, Components and Failure Events, Informatic Structure of the Pilot Experiment of the CEDB, Information Retrieval System for Abnormal Occurrences Reports, Data Bank on Component Reliability Parameters, System on the Exchange of Operation Experience of LWRs, Statistical Data Treatment. Finally, the general conclusions of the feasibility study are summarized: the possibility and the usefulness for the creation of an integrated European Reliability Data System are outlined. (author)

Development of the Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills program for adults on the autism spectrum: Results of initial study.

Science.gov (United States)

Baker-Ericzén, Mary J; Fitch, Meghan A; Kinnear, Mikaela; Jenkins, Melissa M; Twamley, Elizabeth W; Smith, Linda; Montano, Gabriel; Feder, Joshua; Crooke, Pamela J; Winner, Michelle G; Leon, Juan

2018-01-01

The population of adults on the autism spectrum continues to increase, and vocational outcomes are particularly poor. Longitudinal studies of adults with autism spectrum and without intellectual disability have shown consistent and persistent deficits across cognitive, social, and vocational domains, indicating a need for effective treatments of functional disabilities as each impact employment. This initial pilot study is an open trial investigation of the feasibility, acceptability, and initial estimates of outcomes for the newly developed Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills intervention, a manualized "soft skills" curriculum, to enhance both cognitive and social development in adults with autism spectrum. A total of eight adults with autism spectrum, without intellectual disability (78% males), participated in the study. Results support the original hypothesis that adults with autism spectrum can improve both cognitive (i.e. executive functioning) and social cognitive (i.e. social thinking and social communication) abilities. Further Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills was found to be feasible, acceptable, and highly satisfactory for participants and parents. Employment rates more than doubled post-intervention, with an increase from 22% to 56% of participants employed. Conclusion is that Supported Employment, Comprehensive Cognitive Enhancement, and Social Skills has promise as an intervention that can be easily embedded into exiting supported employment vocational training programs to improve cognitive, social, and vocational outcomes.

Blood pressure self-monitoring in pregnancy: examining feasibility in a prospective cohort study.

Science.gov (United States)

Tucker, Katherine L; Taylor, Kathryn S; Crawford, Carole; Hodgkinson, James A; Bankhead, Clare; Carver, Tricia; Ewers, Elizabeth; Glogowska, Margaret; Greenfield, Sheila M; Ingram, Lucy; Hinton, Lisa; Khan, Khalid S; Locock, Louise; Mackillop, Lucy; McCourt, Christine; Pirie, Alexander M; Stevens, Richard; McManus, Richard J

2017-12-28

Raised blood pressure (BP) affects approximately 10% of pregnancies worldwide, and a high proportion of affected women develop pre-eclampsia. This study aimed to evaluate the feasibility of self-monitoring of BP in pregnancy in women at higher risk of pre-eclampsia. This prospective cohort study of self-monitoring BP in pregnancy was carried out in two hospital trusts in Birmingham and Oxford and thirteen primary care practices in Oxfordshire. Eligible women were those defined by the UK National Institute for Health and Care Excellence (NICE) guidelines as at higher risk of pre-eclampsia. A total of 201 participants were recruited between 12 and 16 weeks of pregnancy and were asked to take two BP readings twice daily three times a week through their pregnancy. Primary outcomes were recruitment, retention and persistence of self-monitoring. Study recruitment and retention were analysed with descriptive statistics. Survival analysis was used to evaluate the persistence of self-monitoring and the performance of self-monitoring in the early detection of gestational hypertension, compared to clinic BP monitoring. Secondary outcomes were the mean clinic and self-monitored BP readings and the performance of self-monitoring in the detection of gestational hypertension and pre-eclampsia compared to clinic BP. Of 201 women recruited, 161 (80%) remained in the study at 36 weeks or to the end of their pregnancy, 162 (81%) provided any home readings suitable for analysis, 148 (74%) continued to self-monitor at 20 weeks and 107 (66%) at 36 weeks. Self-monitored readings were similar in value to contemporaneous matched clinic readings for both systolic and diastolic BP. Of the 23 who developed gestational hypertension or pre-eclampsia and self-monitored, 9 (39%) had a raised home BP prior to a raised clinic BP. Self-monitoring of BP in pregnancy is feasible and has potential to be useful in the early detection of gestational hypertensive disorders but maintaining self

A Feasibility Study to Evaluate Wind Energy Potential on the Navajo Nation

Energy Technology Data Exchange (ETDEWEB)

Terry Battiest

2012-11-30

The project, A Feasibility Study to Evaluate Wind Energy Potential on the Navajo Nation, is funded under a solicitation issued by the U.S. Department of Energy Tribal Energy Program. Funding provided by the grant allowed the Navajo Nation to measure wind potential at two sites, one located within the boundaries of the Navajo Nation and the other off-reservation during the project period (September 5, 2005 - September 30, 2009). The recipient for the grant award is the Navajo Tribal Utility Authority (NTUA). The grant allowed the Navajo Nation and NTUA manage the wind feasibility from initial site selection through the decision-making process to commit to a site for wind generation development. The grant activities help to develop human capacity at NTUA and help NTUA to engage in renewable energy generation activities, including not only wind but also solar and biomass. The final report also includes information about development activities regarding the sited included in the grant-funded feasibility study.

Preliminary study on the feasibility of ductless fuel assembly for fast reactors

International Nuclear Information System (INIS)

Shibahara, Itaru; Enokido, Yuji

1988-01-01

Preliminary study on the feasibility of ductless fuel assembly for fast reactors has been conducted. The primary concern is with forecasting the thermal hydraulic characteristics and the heat removal efficiency from the core. The thermal hydraulic analysis revealed the coolant mixing in the core at steady state operating condition was not intensive and the coolant temperature increase was almost proportional to the power of each assembly. The hot spot analysis of the ductless core indicated that the hottest temperature in the core could be comparable with the temperature of the conventional ducted core, even in case the radial power flattening was not actively pursued but with adopting ducted radial blanket assemblies. Under off-normal conditions, the ductless core had improved heat removal capability which was caused by inter-assembly coolant flow. The study has indicated the feasibility of the ductless fuel assembly for fast reactors. The experiments to demonstrate the feasibility will be the next key process for the development. (author)

Anticipatory precrash restraint sensor feasibility study: Final report

Energy Technology Data Exchange (ETDEWEB)

Kercel, S.W.; Dress, W.B.

1995-08-01

This report explores feasibility of an anticipatory precrash restraint sensor. The foundation principle is the anticipation mechanism found at a primitive level of biological intelligence and originally formalized by the mathematical biologist Robert Rosen. A system based on formal anticipatory principles should significantly outperform conventional technologies. It offers the prospect of high payoff in prevention of death and injury. Sensors and processes are available to provide a good, fast, and inexpensive description of the present dynamical state of the vehicle to the embedded system model in the anticipation engine. The experimental part of this study found that inexpensive radar in a real-world setting does return useful data on target dynamics. The data produced by a radar system can be converted to target dynamical information by good, fast and inexpensive signal-processing techniques. Not only is the anticipatory sensor feasible, but further development under the sponsorship of the National Highway Traffic Safety Administration is necessary and desirable. There are a number of possible lines of follow-on investigation. The level of effort and expected benefits of various alternatives are discussed.

Oak Ridge National Laboratory remedial investigation/feasibility study

International Nuclear Information System (INIS)

Glenn, R.D.; Hoffman, J.M.; Hyde, L.D.

1988-01-01

The Oak Ridge National Laboratory (ORNL) Remedial Investigation/ Feasibility Study (RI/FS) began in June 1987 to evaluate 13 contaminated waste area groupings (WAGs) to determine the feasibility and benefits of potential remedial action. The RI/FS and any future remedial action at ORNL will be of national significance and will likely lead to developments that will become models for environmental investigations and cleanups. Bechtel National, Inc. and a team of subcontractors will be working with Martin Marietta Energy systems to conduct intensive field investigations to obtain data required to evaluate the WAGs. The RI/F project continued in FY 1988 with project planning and preparation for field activities. Remedial Investigation (RI) Plans were prepared for 10 of the 13 WAGs. These plans were developed with sufficient information to ensure compliance with regulatory requirements, with intensive attention given to environmental, safety, and health protection; waste management; data management; and quality assurance. This paper reports on the progress made during FY 1988 and discusses activities planned for FY 1989

Cogeneration feasibility study in the Gulf States Utilities service area

Energy Technology Data Exchange (ETDEWEB)

1979-12-01

Sites in the Gulf States Utilities service are considered for cogeneration feasibility studies. The sources of steam considered for the Orange, Texas and Geismar, Lake Charles, and North Baton Rouge, Louisiana sites include oil, coal, HTGR steamers, consolidated nuclear steam system, atmospheric fluidized-bed coal combustion, and coal gasification. Concepts concerning cogeneration fuel systems were categorized by technical applicability as: current technology (pulverized coal-fired boilers and fuel oil-fired boilers), advanced technology under development (HTGR steamers and the CNSS), and advanced technology for future development (atmospheric fluidized-bed boilers and coal gasification). In addition to providing data on cogeneration plant generally useful in the US, the study determined the technical and economic feasibility of steam and electric power cogeneration using coal and nuclear fuels for localized industrial complexes. Details on site selection, plant descriptions, cost estimates, economic analysis, and plant schedule and implementation. (MCW)

Nasal Unit Transplantation: A Cadaveric Anatomical Feasibility Study.

Science.gov (United States)

Dorafshar, Amir H; Mundinger, Gerhard S; Robinson, Brent; Tuffaha, Sami; Brandacher, Gerald; Byrne, Patrick; Walton, Robert L

2017-05-01

Background  The science and technical acumen in the field of vascularized composite allotransplantation has progressed rapidly over the past 15 years, and transplantation of specialized units of the face, such as the nose, appears possible. No study to date has evaluated the technical feasibility of isolated nasal unit transplantation (NUT). In this study, we explore the anatomy and technical specifics of NUT. Methods  In this study, four fresh cadaver heads were studied. Bilateral vascular pedicle dissections were performed in each cadaver. The facial artery was cannulated and injected with food dye under physiologic pressure in two cadavers, and with lead oxide mixture in two cadavers to evaluate perfusion territories supplied by each vascular pedicle. Results  The facial artery and vein were found to be adequate pedicles for NUT. Divergent courses of the vein and artery were consistently identified, which made for a bulky pedicle with necessary inclusion of large amounts of subcutaneous tissue. In all cases, the artery remained superficial, while the vein coursed in a deeper plane, and demonstrated consistent anastomoses with the superior transverse orbital arcade. While zinc oxide injection of the facial artery demonstrated filling of the nasal vasculature across the midline, dye perfusion studies suggested that unilateral arterial inflow may be insufficient to perfuse contralateral NUT components. Discrepancies in these two studies underscore the limitations of nondynamic assessment of nutritive perfusion. Conclusion  NUT based on the facial artery and facial vein is technically feasible. Angiosome evaluation suggests that bilateral pedicle anastomoses may be required to ensure optimal perfusion. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Telephone Care Management of Fall Risk:: A Feasibility Study.

Science.gov (United States)

Phelan, Elizabeth A; Pence, Maureen; Williams, Barbara; MacCornack, Frederick A

2017-03-01

Care management has been found to be more effective than usual care for some chronic conditions, but few studies have tested care management for prevention of elder falls. This study aimed to assess the feasibility and preliminary efficacy of telephone care management of older adults presenting for medical attention due to a fall. The setting was an independent practice association in western Washington serving 1,300 Medicare Advantage-insured patients. Patients aged ≥65 years treated for a fall in an emergency department or their primary care provider's office were contacted via telephone by a care manager within 48 hours of their fall-related visit and invited to participate in a telephone-administered interview to identify modifiable fall risk factors and receive recommendations and follow-up to address identified risk factors. Data from care manager records, patient medical records, and healthcare claims for the first 6 months (November 2009-April 2010) of program implementation were analyzed in 2011. The feasibility of screening and management of fall risk factors over the telephone and the effect on medically attended falls were assessed. Twenty-two patients eligible for fall care management were reached and administered the protocol. Administration took 15-20 minutes and integrated easily with the care manager's other responsibilities. Follow-through on recommendations varied, from 45% for those for whom exercise participation was recommended to 100% for other recommendations. No medically attended falls occurred over 6 months of follow-up. Telephone care management of fall risk appears feasible and may reduce falls requiring medical attention. Copyright © 2016 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

Feasibility study for CPR1000 incore measurement instrumentation educed from the reactor pressure vessel upper head

International Nuclear Information System (INIS)

Guang Jianwei; Liu Qian; Li Wenhong; Duan Yuangang

2010-01-01

The article discusses about the feasibility of in-core measurement instrumentation educed from the reactor pressure vessel (RPV) upper head. Incore instrumentation educed from the reactor pressure vessel upper head is one of advanced technology in the third generation nuclear power plant. This technology can reduce the manufacture problem of RPV; decrease the manufacture time effectively. Furthermore, this technology can get rid of the trouble for loss of water caused by many penetrations in the RPV bottom head, can increase security of nuclear power plant. By the description of structure analysis, comparison, maturity for four type incore instrumentation detectors, the incore instrumentation can be educed from RPV upper head, which can increase reactor's security, reduce the manufacture time, decrease group dose in refueling period. The core design ability can be enhanced through this study. (authors)

The environmental energy sector programme. Poland: Appendices to feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

The appendices contain Energy Law, Act of 10 April 1997 and also more specific details from the feasibility study for the procurement of a financial solution to the modernisation of the combined heat and power plant in the city of Zielona Gora, Poland. (EHS)

Is dignity therapy feasible to enhance the end of life experience for people with motor neurone disease and their family carers?

Directory of Open Access Journals (Sweden)

Bentley Brenda

2012-09-01

Full Text Available Abstract Background Development of interventions that address psychosocial and existential distress in people with motor neurone disease (MND or that alleviate caregiver burden in MND family carers have often been suggested in the research literature. Dignity therapy, which was developed to reduce psychosocial and existential distress at the end of life, has been shown to benefit people dying of cancer and their families. These results may not be transferable to people with MND. The objectives of this study are to assess the feasibility, acceptability and potential effectiveness of dignity therapy to enhance the end of life experience for people with motor neurone disease and their family carers. Methods/design This is a cross-sectional study utilizing a single treatment group and a pre/post test design. The study population will comprise fifty people diagnosed with MND and their nominated family carers. Primarily quantitative outcomes will be gathered through measures assessed at baseline and at approximately one week after the intervention. Outcomes for participants include hopefulness, spirituality and dignity. Outcomes for family carers include perceived caregiver burden, hopefulness and anxiety/depression. Feedback and satisfaction with the intervention will be gathered through a questionnaire. Discussion This detailed research will explore if dignity therapy has the potential to enhance the end of life experience for people with MND and their family carers, and fill a gap for professionals who are called on to address the spiritual, existential and psychosocial needs of their MND patients and families. Trial registration ACTRN Trial Number: ACTRN12611000410954

Enhanced ex-situ bioremediation of soil contaminated with ...

African Journals Online (AJOL)

contaminated soil. Thus, the objective of this study was to investigate the feasibility and effectiveness of using electrical biostimulation processes to enhance ex-situ bioremediation of soils contaminated with organic pollutants. The effect of ...

Awareness Enhancing and Monitoring Device plus Habit Reversal in the Treatment of Trichotillomania: An Open Feasibility Trial.

Science.gov (United States)

Himle, Joseph A; Bybee, Deborah; O'Donnell, Lisa A; Weaver, Addie; Vlnka, Sarah; DeSena, Daniel T; Rimer, Jessica M

2018-01-01

Habit Reversal Therapy (HRT) is helpful for many persons suffering from trichotillomania. However successful habit reversal therapy requires awareness of hair pulling behaviors. Available methods to monitor hair pulling behaviors are less than ideal, particularly when sufferers are unaware of their pulling-related behaviors. This open feasibility trial included 20 persons with trichotillomania who were treated with nine weeks of HRT with experienced clinicians following a well-established HRT protocol. HRT was augmented with an electronic Awareness Enhancing and Monitoring Device (AEMD) designed to alert users of hand to head contact and to monitor the frequency of pulling-related behaviors. The AEMD included a neck unit and two wrist units, each equipped with vibrating alert functions. The results of the open trial revealed significant improvements in trichotillomania symptoms as measured by clinician and self-report rating scales. Most participants met study criteria for HRT completion and treatment effects were large. Participants reported that the AEMD, when operational, was effective in alerting participants to TTM-related behaviors. The monitoring function of the AEMD did not operate as designed. Subjective feedback focused on the AEMD concept was positive but AEMD reliability problems and complaints about the wearability the units were common. Recommendations for AEMD design modifications were included.

Geothermal application feasibility study for the New Mexico Institute of Mining and Technology Campus

Energy Technology Data Exchange (ETDEWEB)

Miller, A.R.

1978-04-01

This study was limited to determining the economic feasibility of providing the space heating, water heating, space cooling, and electrical power needs of New Mexico Tech from geothermal energy. The means of obtaining the required heat and water from the earth, and the possibility of corrosive effects were not part of this study. The results indicate that space heating and water heating are economically feasible if the cost of developing a geothermal source is not included. The major expense then is the pipeline used to convey the energy to the campus. calculations show that this cost is approximately two to three times our current annual heating bill, The study also showed that it would not be economically feasible to provide our relatively small space cooling and electrical energy needs from geothermal energy.

FIRST FEASIBILITY STUDY FOR EXL WITH PROTOTYPE DETECTORS AT THE ESR AND DETECTOR SIMULATIONS

NARCIS (Netherlands)

Kalantar-Nayestanaki, N.; Moeini, H.; Mahjour-Shafiei, M.; Aksouh, F.; Beckert, K.; Beller, P.; Boretzky, K.; Chatillon, A.; Corsi, A.; Egelhof, P.; Emling, H.; Ickert, G.; Ilieva, S.; Kozhuharov, C.; Le Bleis, T.; Le Xuang, X. C.; Litvinov, Y.; Mahata, K.; Meier, J. P.; Nolden, F.; Popp, U.; Simon, H.; Steck, M.; Stoehlker, T.; Weick, H.; Zalite, A.; Kiselev, O.; Jourdan, J.; Kiselev, D.; Werthmueller, D.; Paschalis, S.

This contribution presents some results from the first feasibility measurement performed at GSI using a 350 MeV/nucleon (136)Xe beam and a Hydrogen gas-jet target. In this feasibility study, one element of every possible detection part of the future EXL detection system was investigated. In

Individual music therapy for managing neuropsychiatric symptoms for people with dementia and their carers: a cluster randomised controlled feasibility study.

Science.gov (United States)

Hsu, Ming Hung; Flowerdew, Rosamund; Parker, Michael; Fachner, Jörg; Odell-Miller, Helen

2015-07-18

Previous research highlights the importance of staff involvement in psychosocial interventions targeting neuropsychiatric symptoms of dementia. Music therapy has shown potential effects, but it is not clear how this intervention can be programmed to involve care staff within the delivery of patients' care. This study reports initial feasibility and outcomes from a five month music therapy programme including weekly individual active music therapy for people with dementia and weekly post-therapy video presentations for their carers in care homes. 17 care home residents and 10 care staff were randomised to the music therapy intervention group or standard care control group. The cluster randomised, controlled trial included baseline, 3-month, 5-month and post-intervention 7-month measures of residents' symptoms and well-being. Carer-resident interactions were also assessed. Feasibility was based on carers' feedback through semi-structured interviews, programme evaluations and track records of the study. The music therapy programme appeared to be a practicable and acceptable intervention for care home residents and staff in managing dementia symptoms. Recruitment and retention data indicated feasibility but also challenges. Preliminary outcomes indicated differences in symptoms (13.42, 95 % CI: [4.78 to 22.07; p = 0.006]) and in levels of wellbeing (-0.74, 95 % CI: [-1.15 to -0.33; p = 0.003]) between the two groups, indicating that residents receiving music therapy improved. Staff in the intervention group reported enhanced caregiving techniques as a result of the programme. The data supports the value of developing a music therapy programme involving weekly active individual music therapy sessions and music therapist-carer communication. The intervention is feasible with modifications in a more rigorous evaluation of a larger sample size. Clinicaltrials.gov, number NCT01744600.

Feasibility, safety, acceptability, and functional outcomes of playing Nintendo Wii Fit Plus™ for frail elderly: study protocol for a feasibility trial.

Science.gov (United States)

Gomes, Gisele Cristine Vieira; Bacha, Jéssica Maria Ribeiro; do Socorro Simões, Maria; Lin, Sumika Mori; Viveiro, Larissa Alamino Pereira; Varise, Eliana Maria; Filho, Wilson Jacob; Pompeu, José Eduardo

2017-01-01

Frailty can be defined as a medical syndrome with multiple causes and contributors, characterized by diminished strength and endurance and reduced physiological function that increases the vulnerability to develop functional dependency and/or death. Studies have shown that the most commonly studied exercise protocol for frail older adults is the multimodal training. Interactive video games (IVGs) involve tasks in virtual environments that combine physical and cognitive demands in an attractive and challenging way. The aim of this study will be to evaluate the feasibility, safety, acceptability, and functional outcomes of playing Nintendo Wii Fit Plus TM (NWFP) for frail older adults. The study is a randomized controlled, parallel group, feasibility trial. Participants will be randomly assigned to the experimental group (EG) and control group (CG). The EG will participate in 14 training sessions, each lasting 50 min, twice a week. In each training session, the participants will play five games, with three attempts at each game. The first attempt will be performed with the assistance of a physical therapist to correct the movements and posture of the patients and subsequent attempts will be performed independently. Scores achieved in the games will be recorded. The participants will be evaluated by a blinded physical therapist at three moments: before and after intervention and 30 days after the end of the intervention (follow-up). We will assess the feasibility, acceptability, safety, and clinical outcomes (postural control, gait, cognition, quality of life, mood, and fear of falling). Due to the deficiencies in multiple systems, studies have shown that multimodal interventions including motor-cognitive stimulation can improve the mobility of frail elderly adults. IVGs, among them the NWFP, are considered as a multimodal motor-cognitive intervention that can potentially improve motor and cognitive functions in the frail elderly. However, there is still no evidence

Development of new port in Minahasa Utara: A-pre feasibility study

Science.gov (United States)

Hamzah, Suharman; Abdurahman, Asad; Saputra, Reza; Aprianti, Evi

2017-11-01

In order to support Indonesian Government priority sector to build toll maritime in conjunction to connect "nusantara" as an archipelago country, and also to develop the frontier area of Indonesia, the existence of a port should get more in attention as the gate of Indonesia. A port has significant role in changing of transport mode and at the end as catalyst of economic growth. An important thing from pre-feasibility studies is the priority factor will clearly shown wheather it is good or fair. As a supporting to service passenger moving, container, general cargo and also bulk, a port is necessary to have an excellent design and planning. A pre-feasibility study is required to obtain a scientific basis based on value of interest and the necessity of the region. A pre-feasibility study in this paper aims to identify potential support of the region and giving priority location of development of new port in Minahasa Utara regarding to spatial, government issues, transportation aspect, regional economics, environmental aspect and technical aspect consideration. Experimental Method used are qualitative and quantitative, going through to the data obtained and supported by interview on the spot as well as questionnaire surveys. Result of this paper showing that there are 5 locations suitable with the requirements. Based on the level of priority, high (Kema, Likupang), moderate (Linuhu, Kahuku) and low (Gangga 1).

Feasibility study on the establishment of the IAEA international nuclear university

International Nuclear Information System (INIS)

Lee, E. J.; Kim, Y. T.; Nam, Y. M. and others

2002-09-01

The purpose of this project is to support 2002-2003 the IAEA project D.4.0.2, facilitating education, training and research in nuclear science and related fields, especially for a feasibility study on the establishment of the Agency sponsored International Nuclear University. Through this project, the abstract principle for a feasibility study on the establishment of the Agency sponsored International Nuclear university, which contains the new concepts and its objectives, principles to achieve the objectives, its curriculum outline and operation system, suggested project activities, was developed and submitted to the Agency. The Korean proposal were presented several times at the IAEA meetings and other international meetings related nuclear human resources development for understanding the necessity of a feasibility study on the establishment of the Agency sponsored international nuclear university with Member States. And the Korean proposal included such as the organization of a worldwide network using information and communication technology among Merber States' research institutes and training/education centers, curriculum outline and operation system of the INU will be produced. Also for further cooperation of the IAEA INU project implementation with the Agency, hosting IAEA INIS mirror site, establishment of the RCA region office, establishment of the INTEC at the Korean Atomic Energy Research Institute, and advanced curriculum of nuclear technology linked with NT, BT, ET, IT were made progress as a part of conceptualizing of the IAEA project

Feasibility study on the development of proton accelerator

Energy Technology Data Exchange (ETDEWEB)

Chung, Ki Hyung; Bang, Hyung Chan; Cho, Yong Sup [Seoul National University, Seoul (Korea, Republic of); Kim, Young Rak [Church Environment Research Institute, Seoul (Korea, Republic of); Nam Kung, Won; Cho, Moo Hyun [Pohang University of Science and Technology, Pohang (Korea, Republic of); Seo, Tae Suk [Cartolrik University, Seoul (Korea, Republic of); Woo, Hyung Joo [Nature Research Institute, Seoul (Korea, Republic of); Lee, Kyung Soo [Basic Study Research Institute, Seoul (Korea, Republic of); Lee, Hun Joo [Cheju National University, Cheju (Korea, Republic of); Chang, Soon Hong; Cho, Nam Jin [Korea Advanced Institute of Science and Technology, Taejon (Korea, Republic of); Han, Jeon Kun [Sungkyunkwan University, Seoul (Korea, Republic of)

1996-10-01

A feasibility on the development of a high energy proton accelerator to be used for R and D in the nuclear field of korea was studied. The proposed one is a proton linac with parameters of about 1 GeV, 20 mA which can supply enough neutrons by the spallation reaction to drive a subcritical reactor. It= is expected to solve the intrinsic problem in the nuclear field such as safety, nuclear waste, proliferation and resource. The study was carried out through a multi-institutional cooperation of universities, institute and industry for a national consensus. 5 refs., 8 tabs., 8 figs. (author)

Feasibility study of a single-element transcranial focused ultrasound system for blood-brain barrier opening

Science.gov (United States)

Marquet, Fabrice; Tung, Yao-Sheng; Teichert, Tobias; Ferrera, Vincent P.; Konofagou, Elisa E.

2012-10-01

The blood-brain barrier (BBB) is a specialized vascular system that impedes entry of all large and the vast majority of small molecules including the most potent CNS disease therapeutic agents from entering from the lumen into the brain parenchyma. Microbubble-enhanced, focused ultrasound (ME-FUS) has been previously shown to disrupt noninvasively, selectively, and transiently the BBB in small animals in vivo. The study addresses the focusing properties of single-element transducers at intermediate frequencies (500 kHz) through primate and human skulls, targeting clinically relevant targets extracted from 3D brain atlases such as the hippocampus and the basal ganglia, which are typically affected by early Alzheimer's and Parkinson's disease, respectively. A preliminary in vivo study was performed to study the frequency dependence of BBB opening parameters in mice. Then, feasibility of transcranial ME-FUS BBB opening in non-human primates was demonstrated with subsequent BBB recovery. Sonications were combined with two different types of microbubbles (custom made 4-5 μm and Definity®). 3T MRI was used to confirm the BBB disruption and to assess brain damage.

Perfusion maps of the whole liver based on high temporal and spatial resolution contrast-enhanced MRI (4D THRIVE): Feasibility and initial results in focal liver lesions

International Nuclear Information System (INIS)

Coenegrachts, Kenneth; Ghekiere, Johan; Denolin, Vincent; Gabriele, Beck; Herigault, Gwen; Haspeslagh, Marc; Daled, Peter; Bipat, Shandra; Stoker, Jaap; Rigauts, Hans

2010-01-01

Purpose: To prospectively evaluate a new imaging sequence (4D THRIVE) for whole liver perfusion in high temporal and spatial resolution. Feasibility of parametric mapping and its potential for characterizing focal liver lesions (FLLs) are investigated. Materials and methods: Fifteen patients suspected for colorectal liver metastases (LMs) were included. Parametric maps were evaluated qualitatively (ring-enhancement and lesion heterogeneity) and compared to three-phased contrast-enhanced MRI. Quantitative analysis was based on average perfusion values of entire FLLs. Reference standard comprised surgery with histopathology or follow-up imaging. Fisher's exact test was used for qualitative and Kruskal-Wallis test for quantitative analysis. Results: In total 29 LMs, 17 hemangiomas and 4 focal nodular hyperplasias were evaluated. FLLs could be differentiated by qualitative assessment of parametric maps respectively three-phased contrast-enhanced MRI (Fisher's p < 0.001 for comparisons between LMs and hemangiomas and LMs and FNHs for both ring-enhancement and lesion heterogeneity) rather than by quantitative analysis of parametric maps (Chi-square for Kep = 0.33 (p = 0.847) and Chi-square for Kel = 1.35 (p = 0.509)). Conclusion: This preliminary study shows potential of 4D THRIVE for whole liver imaging enabling calculation of parametric maps. Qualitative rather than quantitative analysis was accurate for differentiating malignant and benign FLLs.

Feasibility and Effectiveness of a Web-Based Physical Activity Intervention for Working Mothers.

Science.gov (United States)

Mailey, Emily L; Huberty, Jennifer; Irwin, Brandon C

2016-08-01

The purpose of this study was to examine the feasibility and effectiveness of a web-based intervention to promote physical activity and self-worth among working mothers. Participants (N = 69) were randomly assigned to receive a standard web-based intervention or an enhanced intervention that included group dynamics strategies to promote engagement. The 8-week intervention was guided by self-determination theory. Each week, participants were instructed to complete 3 tasks: listen to a podcast related to well-being, complete a workbook assignment, and communicate with other participants on a discussion board. Participants in the enhanced condition received an additional weekly task to enhance group cohesion. Data were collected at baseline, week 8, and week 16. Physical activity (P working mothers. Group dynamics strategies only minimally enhanced user engagement, and future studies are needed to optimize web-based intervention designs.

Economic and technical feasibility study of compressed air storage

Energy Technology Data Exchange (ETDEWEB)

1976-03-01

The results of a study of the economic and technical feasibility of compressed air energy storage (CAES) are presented. The study, which concentrated primarily on the application of underground air storage with combustion turbines, consisted of two phases. In the first phase a general assessment of the technical alternatives, economic characteristics and the institutional constraints associated with underground storage of compressed air for utility peaking application was carried out. The goal of this assessment was to identify potential barrier problems and to define the incentive for the implementation of compressed air storage. In the second phase, the general conclusions of the assessment were tested by carrying out the conceptual design of a CAES plant at two specific sites, and a program of further work indicated by the assessment study was formulated. The conceptual design of a CAES plant employing storage in an aquifer and that of a plant employing storage in a conventionally excavated cavern employing a water leg to maintain constant pressure are shown. Recommendations for further work, as well as directions of future turbo-machinery development, are made. It is concluded that compressed air storage is technically feasible for off-peak energy storage, and, depending on site conditions, CAES plants may be favored over simple cycle turbine plants to meet peak demands. (LCL)

Feasibility Study Analysis of Establishing Archery Sports Special Place

Science.gov (United States)

Tarigan, U. P. P.; Mardhatillah, A.; Budiman, I.; Sembiring, A. C.; Ramadhan, M. S.

2018-04-01

This study essentially discusses the basic concepts related to the decision and process of selecting a sports archery business project in order to provide economic and social benefits over time. Archery sports is a sport that requires special skills, both accuracy, coordination mental training and improves the physical condition of the prime. In Medan, it's still a bit of practice archery, but many people love this sport. From the data collected, there are three locations where archery in the city of the field of the Sunggal Knights is located at Jl Tunggul Hitam no.1A, Kec. Medan Sunggal, Avros Educational Park Aval address at Avros Street No.60 Medan, and the Knights of Johor Archery Club which is located at Jl. The work of Darma Gg. Ujung Family, Medan Johor. Therefore a feasibility study was undertaken in establishing an archery sports place in the field. The aspects to be considered in making feasibility studies are market and marketing aspects, technical and equipment aspects, management aspects, legal aspects, economic and social aspects, and financial aspects. Financial analysis using own capital got Payback Period 3 years 5,8 months, Net Present Value Rp 11.684.026 and obtained Internal Rate of Return of 17%.

Training Corrective Maintenance Performance on Electronic Equipment with CAI Terminals: I. A Feasibility Study.

Science.gov (United States)

Rigney, Joseph W.

A report is given of a feasibility study in which several possible relationships between student, computer terminal, and electronic equipment were considered. The simplest of these configurations was set up and examined in terms of its feasibility for teaching the performance of fault localization on a Navy transceiver. An instructional program…

Krypton-enhanced ventilation CT with dual energy technique: experimental study for optimal krypton concentration.

Science.gov (United States)

Chung, Yong Eun; Hong, Sae Rom; Lee, Mi-Jung; Lee, Myungsu; Lee, Hye-Jeong

2014-11-01

To assess the feasibility of krypton-enhanced ventilation CT using dual energy (DE) technique for various krypton concentrations and to determine the appropriate krypton concentration for DE ventilation CT through an animal study. Baseline DECT was first performed on seven New Zealand white rabbits. The animals were then ventilated using 20%, 30%, 40%, 50%, 60%, to 70% krypton concentration, and DECT was performed for each concentration. Krypton extraction was performed through a workstation, and results were displayed on a color map. Overlay Hounsfield unit (HU) values were obtained by two observers in consensus readings. A linear mixed model was used to correlate overlay HU values and krypton concentrations. Visual assessments of the homogeneity of krypton maps were also performed. Mean overlay HU values according to krypton concentration were as follows; 20% krypton, 1.68 ± 5.15; 30% krypton, 3.73 ± 5.93; 40% krypton, 6.92 ± 5.51; 50% krypton, 10.88 ± 5.17; 60% krypton, 14.54 ± 4.23; and 70% krypton, 18.79 ± 3.63. We observed a significant correlation between overlay HU values on krypton maps and krypton concentrations (P krypton color maps, all observers determined universal enhancement on the 70% krypton map for all animals. It is feasible to evaluate lung ventilation function using DECT with a krypton concentration of at least 70%.

A quasi-randomised, controlled, feasibility trial of GLITtER (Green Light Imaging Interpretation to Enhance Recovery—a psychoeducational intervention for adults with low back pain attending secondary care

Directory of Open Access Journals (Sweden)

Emma L. Karran

2018-02-01

Full Text Available Background Although it is broadly accepted that clinicians should endeavour to reassure patients with low back pain, to do so can present a significant clinical challenge. Guidance for how to provide effective reassurance is scarce and there may be a need to counter patient concerns arising from misinterpretation of spinal imaging findings. ‘GLITtER’ (Green Light Imaging Intervention to Enhance Recovery was developed as a standardised method of communicating imaging findings in a manner that is reassuring and promotes engagement in an active recovery. This feasibility study is an important step towards definitive testing of its effect. Methods This feasibility study was a prospective, quasi-randomised, parallel trial with longitudinal follow-up, involving sampling of patients attending a spinal outpatient clinic at a metropolitan hospital. English speaking adults (18–75 years presenting to the clinic with low back pain and prior spinal imaging were considered for inclusion. Eligible patients were allocated to receive a GLITtER consultation or a standard consultation (as determined by appointment scheduling and clinician availability, and were blinded to their allocation. Full details of the GLITtER intervention are described in accordance with the Tidier template.Follow-up data were collected after 1 and 3 months. The primary outcome of this study was the fulfillment of specific feasibility criteria which were established a priori. Determination of a sample size for a definitive randomised controlled trial was a secondary objective. Results Two hundred seventy-six patients underwent preliminary screening and 31 patients met the final eligibility criteria for study inclusion. Seventeen participants were allocated to the intervention group and 14 were allocated to the control group. Three month follow-up data were available from 42% of the 31 enrolled participants (N = 13, six intervention, seven control. Feasibility indicators for consent

A quasi-randomised, controlled, feasibility trial of GLITtER (Green Light Imaging Interpretation to Enhance Recovery)-a psychoeducational intervention for adults with low back pain attending secondary care.

Science.gov (United States)

Karran, Emma L; Hillier, Susan L; Yau, Yun-Hom; McAuley, James H; Moseley, G Lorimer

2018-01-01

Although it is broadly accepted that clinicians should endeavour to reassure patients with low back pain, to do so can present a significant clinical challenge. Guidance for how to provide effective reassurance is scarce and there may be a need to counter patient concerns arising from misinterpretation of spinal imaging findings. 'GLITtER' (Green Light Imaging Intervention to Enhance Recovery) was developed as a standardised method of communicating imaging findings in a manner that is reassuring and promotes engagement in an active recovery. This feasibility study is an important step towards definitive testing of its effect. This feasibility study was a prospective, quasi-randomised, parallel trial with longitudinal follow-up, involving sampling of patients attending a spinal outpatient clinic at a metropolitan hospital. English speaking adults (18-75 years) presenting to the clinic with low back pain and prior spinal imaging were considered for inclusion. Eligible patients were allocated to receive a GLITtER consultation or a standard consultation (as determined by appointment scheduling and clinician availability), and were blinded to their allocation. Full details of the GLITtER intervention are described in accordance with the Tidier template.Follow-up data were collected after 1 and 3 months. The primary outcome of this study was the fulfillment of specific feasibility criteria which were established a priori . Determination of a sample size for a definitive randomised controlled trial was a secondary objective. Two hundred seventy-six patients underwent preliminary screening and 31 patients met the final eligibility criteria for study inclusion. Seventeen participants were allocated to the intervention group and 14 were allocated to the control group. Three month follow-up data were available from 42% of the 31 enrolled participants ( N  = 13, six intervention, seven control). Feasibility indicators for consent, resource burden and acceptability of the

Practice Study Outpatient Psychotherapy - Switzerland (PAP-S) : Study design and feasibility (Revised edition)

OpenAIRE

Wyl, Agnes von; Crameri, Aureliano; Koemeda, Margit; Tschuschke, Volker; Schulthess, Peter

2016-01-01

Revised edition of Von Wyl, A., Crameri, A., Koemeda, M., Tschuchke, V. & Schulthess, P. (2013). The PAP-S (Practice of Ambulant Psychotherapy-Study), Switzerland: Study Design and Feasibility. Zurich University of Applied Sciences, Zurich. The original article was published in German: von Wyl, A., Crameri, A., Koemeda, M., Tschuschke, V. & Schulthess, P. (2013). Praxisstudie ambulante Psychotherapie Schweiz (PAP-S): Studiendesign und Machbarkeit. Psychotherapie-Wissenschaft, 1, 6-22; op...

Feasibility study report for Operable Unit 4: Volume 1

International Nuclear Information System (INIS)

1994-02-01

This report documents the Feasibility Study (FS) phase of the Fernald Environmental Management Project (FEMP) Operable Unit 4 Remedial Investigation/Feasibility Study (RI/FS) Program. The FEMP, formerly known as the Feed Materials Production Center (FMPC), is a US Department of Energy (DOE) facility that operated from 1952 to 1989. The facility's primarily function was to provide high purity uranium metal products to support United States defense programs. Production operations were suspended in 1989 to focus on environmental restoration and waste management activities at the facility. The RI/FS is being conducted pursuant to the terms of a Consent Agreement between DOE and the US Environmental Protection Agency (EPA) under Sections 120 and 106(a) of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. The Ohio Environmental Protection Agency (OEPA) is also participating in the RI/FS process at the FEMP through direct involvement in program review meetings and technical review of project documentation. The objective of the RI/FS process is to gather information to support an informed risk management decision regarding which remedy appears to be the most appropriate action for addressing the environmental concerns identified at the FEMP

Solar feasibility study for site-specific industrial-process-heat applications. Final report

Energy Technology Data Exchange (ETDEWEB)

Murray, O.L.

1980-03-18

This study addresses the technical feasibility of solar energy in industrial process heat (IPH) applications in Mid-America. The study was one of two contracted efforts covering the MASEC 12-state region comprised of: Illinois, Michigan, North Dakota, Indiana, Minnesota, Ohio, Iowa, Missouri, South Dakota, Kansas, Nebraska, Wisconsin. The results of our study are encouraging to the potential future role of solar energy in supplying process heat to a varied range of industries and applications. We identified and developed Case Study documentation of twenty feasible solar IPH applications covering eight major SIC groups within the Mid-American region. The geographical distribution of these applications for the existing range of solar insolation levels are shown and the characteristics of the applications are summarized. The results of the study include process identification, analysis of process heat requirements, selection of preliminary solar system characteristics, and estimation of system performance and cost. These are included in each of the 20 Case Studies. The body of the report is divided into two primary discussion sections dealing with the Study Methodology employed in the effort and the Follow-On Potential of the identified applications with regard to possible demonstration projects. The 20 applications are rated with respect to their relative overall viability and procedures are discussed for possible demonstration project embarkment. Also, a possible extension of this present feasibility study for late-comer industrial firms expressing interest appears worthy of consideration.

Enhancing mHealth Technology in the Patient-Centered Medical Home Environment to Activate Patients With Type 2 Diabetes: A Multisite Feasibility Study Protocol.

Science.gov (United States)

Gimbel, Ronald; Shi, Lu; Williams, Joel E; Dye, Cheryl J; Chen, Liwei; Crawford, Paul; Shry, Eric A; Griffin, Sarah F; Jones, Karyn O; Sherrill, Windsor W; Truong, Khoa; Little, Jeanette R; Edwards, Karen W; Hing, Marie; Moss, Jennie B

2017-03-06

The potential of mHealth technologies in the care of patients with diabetes and other chronic conditions has captured the attention of clinicians and researchers. Efforts to date have incorporated a variety of tools and techniques, including Web-based portals, short message service (SMS) text messaging, remote collection of biometric data, electronic coaching, electronic-based health education, secure email communication between visits, and electronic collection of lifestyle and quality-of-life surveys. Each of these tools, used alone or in combination, have demonstrated varying degrees of effectiveness. Some of the more promising results have been demonstrated using regular collection of biometric devices, SMS text messaging, secure email communication with clinical teams, and regular reporting of quality-of-life variables. In this study, we seek to incorporate several of the most promising mHealth capabilities in a patient-centered medical home (PCMH) workflow. We aim to address underlying technology needs and gaps related to the use of mHealth technology and the activation of patients living with type 2 diabetes. Stated differently, we enable supporting technologies while seeking to influence patient activation and self-care activities. This is a multisite phased study, conducted within the US Military Health System, that includes a user-centered design phase and a PCMH-based feasibility trial. In phase 1, we will assess both patient and provider preferences regarding the enhancement of the enabling technology capabilities for type 2 diabetes chronic care management. Phase 2 research will be a single-blinded 12-month feasibility study that incorporates randomization principles. Phase 2 research will seek to improve patient activation and self-care activities through the use of the Mobile Health Care Environment with tailored behavioral messaging. The primary outcome measure is the Patient Activation Measure scores. Secondary outcome measures are Summary of

Assessing the feasibility of the Effectiveness of Discontinuing Bisphosphonates trial: a pilot study.

Science.gov (United States)

Wright, N C; Foster, P J; Mudano, A S; Melnick, J A; Lewiecki, M E; Shergy, W J; Curtis, J R; Cutter, G R; Danila, M I; Kilgore, M L; Lewis, E C; Morgan, S L; Redden, D T; Warriner, A H; Saag, K G

2017-08-01

The Effectiveness of Discontinuing Bisphosphonates (EDGE) study is a planned pragmatic clinical trial to guide "drug holiday" clinical decision making. This pilot study assessed work flow and feasibility of such a study. While participant recruitment and treatment adherence were suboptimal, administrative procedures were generally feasible and minimally disrupted clinic flow. The comparative effectiveness of continuing or discontinuing long-term alendronate (ALN) on fractures is unknown. A large pragmatic ALN discontinuation study has potential to answer this question. We conducted a 6-month pilot study of the planned the EDGE study among current long-term ALN users (women aged ≥65 with ≥3 years of ALN use) to determine study work flow and feasibility including evaluating the administrative aspects of trial conduct (e.g., time to contract, institutional review board (IRB) approval), assessing rates of site and participant recruitment, and evaluating post-randomization outcomes, including adherence, bisphosphonate-associated adverse events, and participant and site satisfaction. We assessed outcomes 1 and 6 months after randomization. Nine sites participated, including seven community-based medical practices and two academic medical centers. On average (SD), contract execution took 3.4 (2.3) months and IRB approval took 13.9 (4.1) days. Sites recruited 27 participants (13 to continue ALN and 14 to discontinue ALN). Over follow-up, 22% of participants did not adhere to their randomization assignment: 30.8% in the continuation arm and 14.3% in the discontinuation arm. No fractures or adverse events were reported. Sites reported no issues regarding work flow, and participants were highly satisfied with the study. Administrative procedures of the EDGE study were generally feasible, with minimal disruption to clinic flow. In this convenience sample, participant recruitment was suboptimal across most practice sites. Accounting for low treatment arm adherence, a

Biodiesel feasibility study: An evaluation of material compatibility; performance; emission and engine durability

Energy Technology Data Exchange (ETDEWEB)

Fazal, M.A.; Haseeb, A.S.M.A.; Masjuki, H.H. [Department of Mechanical Engineering, University of Malaya, 50603 Kuala Lumpur (Malaysia)

2011-02-15

Biodiesel, derived from the transesterification of vegetable oils or animal fats, is composed of saturated and unsaturated long-chain fatty acid alkyl esters. In spite of having some application problems, recently it is being considered as one of the most promising alternative fuels in internal combustion engine. From scientific literatures, this paper has collected and analyzed the data on both advantages and disadvantages of biodiesel over conventional diesel. Since the aim of this study is to evaluate the biodiesel feasibility in automobiles, the first section is dedicated to materials compatibility in biodiesel as compared to that in diesel. The highest consensus is related to enhanced corrosion of automotive parts due to its compositional differences. In the subsequent sections, data on performance, emission and engine durability have been analyzed and compared. In this case, the highest consensus is found in reducing emissions as well as in increasing moving parts sticking, injector coking and filter plugging. This paper has also summarized the factors of biodiesel in contributing these technical performances. (author)

Feasibility Study and Demonstration of an Aluminum and Ice Solid Propellant

Directory of Open Access Journals (Sweden)

Timothee L. Pourpoint

2012-01-01

Full Text Available Aluminum-water reactions have been proposed and studied for several decades for underwater propulsion systems and applications requiring hydrogen generation. Aluminum and water have also been proposed as a frozen propellant, and there have been proposals for other refrigerated propellants that could be mixed, frozen in situ, and used as solid propellants. However, little work has been done to determine the feasibility of these concepts. With the recent availability of nanoscale aluminum, a simple binary formulation with water is now feasible. Nanosized aluminum has a lower ignition temperature than micron-sized aluminum particles, partly due to its high surface area, and burning times are much faster than micron aluminum. Frozen nanoscale aluminum and water mixtures are stable, as well as insensitive to electrostatic discharge, impact, and shock. Here we report a study of the feasibility of an nAl-ice propellant in small-scale rocket experiments. The focus here is not to develop an optimized propellant; however improved formulations are possible. Several static motor experiments have been conducted, including using a flight-weight casing. The flight weight casing was used in the first sounding rocket test of an aluminum-ice propellant, establishing a proof of concept for simple propellant mixtures making use of nanoscale particles.

Piloting the feasibility of head-mounted video technology to augment student feedback during simulated clinical decision-making: An observational design pilot study.

Science.gov (United States)

Forbes, Helen; Bucknall, Tracey K; Hutchinson, Alison M

2016-04-01

Clinical decision-making is a complex activity that is critical to patient safety. Simulation, augmented by feedback, affords learners the opportunity to learn critical clinical decision-making skills. More detailed feedback following simulation exercises has the potential to further enhance student learning, particularly in relation to developing improved clinical decision-making skills. To investigate the feasibility of head-mounted video camera recordings, to augment feedback, following acute patient deterioration simulations. Pilot study using an observational design. Ten final-year nursing students participated in three simulation exercises, each focussed on detection and management of patient deterioration. Two observers collected behavioural data using an adapted version of Gaba's Clinical Simulation Tool, to provide verbal feedback to each participant, following each simulation exercise. Participants wore a head-mounted video camera during the second simulation exercise only. Video recordings were replayed to participants to augment feedback, following the second simulation exercise. Data were collected on: participant performance (observed and perceived); participant perceptions of feedback methods; and head-mounted video camera recording feasibility and capability for detailed audio-visual feedback. Management of patient deterioration improved for six participants (60%). Increased perceptions of confidence (70%) and competence (80%), were reported by the majority of participants. Few participants (20%) agreed that the video recording specifically enhanced their learning. The visual field of the head-mounted video camera was not always synchronised with the participant's field of vision, thus affecting the usefulness of some recordings. The usefulness of the video recordings, to enhance verbal feedback to participants on detection and management of simulated patient deterioration, was inconclusive. Modification of the video camera glasses, to improve

FBI fingerprint identification automation study. AIDS 3 evaluation report. Volume 4: Economic feasibility

Science.gov (United States)

Mulhall, B. D. L.

1980-01-01

The results of the economic analysis of the AIDS 3 system design are presented. AIDS 3 evaluated a set of economic feasibility measures including life cycle cost, implementation cost, annual operating expenditures and annual capital expenditures. The economic feasibility of AIDS 3 was determined by comparing the evaluated measures with the same measures, where applicable, evaluated for the current system. A set of future work load scenarios was constructed using JPL's environmental evaluation study of the fingerprint identification system. AIDS 3 and the current system were evaluated for each of the economic feasibility measures for each of the work load scenarios. They were compared for a set of performance measures, including response time and accuracy, and for a set of cost/benefit ratios, including cost per transaction and cost per technical search. Benefit measures related to the economic feasibility of the system are also presented, including the required number of employees and the required employee skill mix.

Nurse- and peer-led self-management programme for patients with an implantable cardioverter defibrillator; a feasibility study

Directory of Open Access Journals (Sweden)

van Eijk Jacques

2007-09-01

Full Text Available Abstract Background The prevalence of cardiovascular disease is increasing. Improved treatment options increase survival after an acute myocardial infarction or sudden cardiac arrest, although patients often have difficulty adjusting and regaining control in daily life. In particular, patients who received an implantable cardioverter defibrillator (ICD experience physical and psychological problems. Interventions to enhance perceived control and acceptance of the device are therefore necessary. This paper describes a small-scale study to explore the feasibility and the possible benefits of a structured nurse- and peer-led self-management programme ('Chronic Disease Self-Management Program' – CDSMP among ICD patients. Methods Ten male ICD patients (mean age = 65.5 years participated in a group programme, consisting of six sessions, led by a team consisting of a nurse specialist and a patient with cardiovascular disease. Programme feasibility was evaluated among patients and leaders by measuring performance of the intervention according to protocol, attendance and adherence of the participating ICD patients, and patients' and leaders' opinions about the programme. In addition, before and directly after attending the intervention, programme benefits (e.g. perceived control, symptoms of anxiety and depression, and quality of life were assessed. Results The programme was conducted largely according to protocol. Eight patients attended at least four sessions, and adherence ranged from good to very good. On average, the patients reported to have benefited very much from the programme, which they gave an overall report mark of 8.4. The leaders considered the programme feasible as well. Furthermore, improvements were identified for general self-efficacy expectancies, symptoms of anxiety, physical functioning, social functioning, role limitations due to physical problems, and pain. Conclusion This study suggests that a self-management programme led by a

Bin Set 1 Calcine Retrieval Feasibility Study

International Nuclear Information System (INIS)

Adams, R.D.; Berry, S.M.; Galloway, K.J.; Langenwalter, T.A.; Lopez, D.A.; Noakes, C.M.; Peterson, H.K.; Pope, M.I.; Turk, R.J.

1999-01-01

At the Department of Energy's Idaho Nuclear Technology and Engineering Center, as an interim waste management measure, both mixed high-level liquid waste and sodium bearing waste have been solidified by a calculation process and are stored in the Calcine Solids Storage Facilities. This calcined product will eventually be treated to allow final disposal in a national geologic repository. The Calcine Solids Storage Facilities comprise seven ''bit sets.'' Bin Set 1, the first to be constructed, was completed in 1959, and has been in service since 1963. It is the only bin set that does not meet current safe-shutdown earthquake seismic criteria. In addition, it is the only bin set that lacks built-in features to aid in calcine retrieval. One option to alleviate the seismic compliance issue is to transport the calcine from Bin Set 1 to another bin set which has the required capacity and which is seismically qualified. This report studies the feasibility of retrieving the calcine from Bi n Set 1 and transporting it into Bin Set 6 which is located approximately 650 feet away. Because Bin Set 1 was not designed for calcine retrieval, and because of the high radiation levels and potential contamination spread from the calcined material, this is a challenging engineering task. This report presents preconceptual design studies for remotely-operated, low-density, pneumatic vacuum retrieval and transport systems and equipment that are based on past work performed by the Raytheon Engineers and Constructors architectural engineering firm. The designs presented are considered feasible; however, future development work will be needed in several areas during the subsequent conceptual design phase

Bin Set 1 Calcine Retrieval Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

R. D. Adams; S. M. Berry; K. J. Galloway; T. A. Langenwalter; D. A. Lopez; C. M. Noakes; H. K. Peterson; M. I. Pope; R. J. Turk

1999-10-01

At the Department of Energy's Idaho Nuclear Technology and Engineering Center, as an interim waste management measure, both mixed high-level liquid waste and sodium bearing waste have been solidified by a calculation process and are stored in the Calcine Solids Storage Facilities. This calcined product will eventually be treated to allow final disposal in a national geologic repository. The Calcine Solids Storage Facilities comprise seven ''bit sets.'' Bin Set 1, the first to be constructed, was completed in 1959, and has been in service since 1963. It is the only bin set that does not meet current safe-shutdown earthquake seismic criteria. In addition, it is the only bin set that lacks built-in features to aid in calcine retrieval. One option to alleviate the seismic compliance issue is to transport the calcine from Bin Set 1 to another bin set which has the required capacity and which is seismically qualified. This report studies the feasibility of retrieving the calcine from Bi n Set 1 and transporting it into Bin Set 6 which is located approximately 650 feet away. Because Bin Set 1 was not designed for calcine retrieval, and because of the high radiation levels and potential contamination spread from the calcined material, this is a challenging engineering task. This report presents preconceptual design studies for remotely-operated, low-density, pneumatic vacuum retrieval and transport systems and equipment that are based on past work performed by the Raytheon Engineers and Constructors architectural engineering firm. The designs presented are considered feasible; however, future development work will be needed in several areas during the subsequent conceptual design phase.

Feasibility of the Dutch ICF Activity Inventory: a pilot study

Directory of Open Access Journals (Sweden)

van Nispen Ruth MA

2010-11-01

Full Text Available Abstract Background Demographic ageing will lead to increasing pressure on visual rehabilitation services, which need to be efficiently organised in the near future. The Dutch ICF Activity Inventory (D-AI was developed to assess the rehabilitation needs of visually impaired persons. This pilot study tests the feasibility of the D-AI using a computer-assisted telephone interview. Methods In addition to the regular intake, the first version of the D-AI was assessed in 20 patients. Subsequently, patients and intake assessors were asked to fill in an evaluation form. Based on these evaluations, a new version of the D-AI was developed. Results Mean administration time of the D-AI was 88.8 (± 41.0 minutes. Overall, patients and assessors were positive about the D-AI assessment. However, professionals and 60% of the patients found the administration time to be too long. All included items were considered relevant and only minor adjustments were recommended. Conclusion The systematic character of the revised D-AI will prevent topics from being overlooked and indicate which needs have the highest priority from a patient-centred perspective. Moreover, ongoing assessment of the D-AI will enhance evaluation of the rehabilitation process. To decrease administration time, in the revised D-AI only the top priority goals will be fully assessed. Using the D-AI, a rehabilitation plan based on individual needs can be developed for each patient. Moreover, it enables better evaluation of the effects of rehabilitation. A larger validation study is planned.

Feasibility studies of colorless LR 115 SSNTD for alpha-particle radiobiological experiments

International Nuclear Information System (INIS)

Chan, K.F.; Tse, A.K.W.; Fong, W.F.; Yu, K.N.

2006-01-01

The feasibility of using the active layer of the colorless LR 115 SSNTD for alpha-particle radiobiological experiments was studied. The track revelation time on the bottom side (the side attached to the polyester base) was much longer than that on the top side (the side not attached to the polyester base) of the active layer so track formation on the top side was more desirable. In relation to this, culture of HeLa cells on the bottom side of the active layer was found feasible although the cultured cell number was relatively smaller. The feasibility of using this SSNTD for alpha-particle radiobiological experiments was demonstrated by culturing cells on the bottom side while performing alpha-particle irradiation and chemical etching on the top side, and by taking photographs of the cells and alpha-particle tracks together under the optical microscope

A behavioral medicine intervention for older women living alone with chronic pain – a feasibility study

Directory of Open Access Journals (Sweden)

Cederbom S

2014-08-01

the study procedure and interventions have to be refined and tested in a larger feasibility study to be able to evaluate the effects of these kinds of interventions on pain-related disability, pain-related beliefs, self-efficacy in everyday activities, and morale in the target group. Further research is also needed to refine and evaluate effects from individualized reminder routines, support to collect self-report data, safety procedures for balance training, and training of personnel to enhance self-efficacy. Keywords: biopsychosocial model, community-dwelling, elderly, female, exercise intervention, physical therapy

Feasibility of a novel participatory multi-sector continuous improvement approach to enhance food security in remote Indigenous Australian communities.

Science.gov (United States)

Brimblecombe, J; Bailie, R; van den Boogaard, C; Wood, B; Liberato, S C; Ferguson, M; Coveney, J; Jaenke, R; Ritchie, J

2017-12-01

Food insecurity underlies and compounds many of the development issues faced by remote Indigenous communities in Australia. Multi-sector approaches offer promise to improve food security. We assessed the feasibility of a novel multi-sector approach to enhance community food security in remote Indigenous Australia. A longitudinal comparative multi-site case study, the Good Food Systems Good Food for All Project, was conducted (2009-2013) with four Aboriginal communities. Continuous improvement meetings were held in each community. Data from project documents and store sales were used to assess feasibility according to engagement, uptake and sustainability of action, and impact on community diet, as well as identifying conditions facilitating or hindering these. Engagement was established where: the community perceived a need for the approach; where trust was developed between the community and facilitators; where there was community stability; and where flexibility was applied in the timing of meetings. The approach enabled stakeholders in each community to collectively appraise the community food system and plan action. Actions that could be directly implemented within available resources resulted from developing collaborative capacity. Actions requiring advocacy, multi-sectoral involvement, commitment or further resources were less frequently used. Positive shifts in community diet were associated with key areas where actions were implemented. A multi-sector participatory approach seeking continuous improvement engaged committed Aboriginal and non-Aboriginal stakeholders and was shown to have potential to shift community diet. Provision of clear mechanisms to link this approach with higher level policy and decision-making structures, clarity of roles and responsibilities, and processes to prioritise and communicate actions across sectors should further strengthen capacity for food security improvement. Integrating this approach enabling local decision-making into

Coeur d'Alene Tribe Energy Efficiency Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Allgood, Tiffany L. [Coeur d' Alene Tribe, Plummer, ID (United States); Sorter, Andy [Coeur d' Alene Tribe, Plummer, ID (United States)

2014-09-01

The Coeur d'Alene Tribe's Energy Efficiency Feasibility Study (EEFS) is the culminating document that compiles the energy efficiency and building performance assessment and project prioritization process completed on 36 Tribally owned and operated facilities within Tribal lands. The EEFS contains sections on initial findings, utility billing analyses, energy conservation measures and prioritization and funding sources and strategies for energy project implementation.

Feasibility study report for Operable Unit 4: Fernald Environmental Management Project, Fernald, Ohio: Remedial investigation and feasibility study: Volume 3: Final report

International Nuclear Information System (INIS)

1994-02-01

This report documents the Feasibility Study (FS) phase of the Fernald Environmental Management Project (FEMP) Operable Unit 4 Remedial Investigation/Feasibility Study (RI/FS) Program. The FEMP, formerly known as the Feed Materials Production Center (FMPC), is a US Department of Energy (DOE) facility that operated from 1952 to 1989. The facility's primarily function was to provide high purity uranium metal products to support United States defense programs. Production operations were suspended in 1989 to focus on environmental restoration and waste management activities at the facility. The RI/FS is being conducted pursuant to the terms of a Consent Agreement between DOE and the US Environmental Protection Agency (EPA) under Sections 120 and 106(a) of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. The Ohio Environmental Protection Agency (OEPA) is also participating in the RI/FS process at the FEMP through direct involvement in program review meetings and technical review of project documentation. The objective of the RI/FS process is to gather information to support an informed risk management decision regarding which remedy appears to be the most appropriate action for addressing the environmental concerns identified at the FEMP. This volume contains appendices F--J

[Feasibility study for whole plant medicinal use of Tribulus terrestris].

Science.gov (United States)

Yang, Li; Wang, Chunyu; Han, Meiw; Yang, Limin

2009-09-01

The content differences of leaf, plant and fruit of Tribulus terrestris was compared to study the feasibility of whole plant medicinal use. The samples were collected in three typical habitats and six different production areas of T. terrestris. The main medicinal ingredients saponins and flavonoids were determined in root, stem, leaf and fruit during the harvest time. The two ingredients were abounded in leaf and more than 2.61 times as in other parts of the plant. The results showed that there were no differences between the whole plant and the fruit. It should pay more attentions on the collection, preservation and utilization of the leaf of T. terrestris in the harvesting and processing stage. The whole plant for medical use was feasibility based on the content of the ingredients.

Feasibility study of micro-filtration for algae separation in an innovative nuclear effluents decontamination process

International Nuclear Information System (INIS)

Gouvion Saint Cyr, D. de; Wisniewski, C.; Schrive, L.; Farhi, E.; Rivasseau, C.

2014-01-01

Bio-remediation technologies often offer efficiency, cost and environmental impact benefits against physico-chemical technologies. Concerning the remediation of radionuclide-containing water, a few bio-based technologies have been proposed but none is currently operational in highly radioactive environments. A new radio-tolerant micro-alga, isolated from a nuclear facility, possesses properties that offer new decontamination prospects for the nuclear industry or for the clean-up of environmental water. A pilot-scale treatment unit based on this alga is currently under development for the decontamination of radioactive water. It includes separation and/or concentration steps relying on membrane filtration. This work aims at verifying the feasibility of micro-filtration as separation step for the targeted algae separation. Recommendations about the choice of operating conditions limiting and/or controlling the membrane fouling are provided with the objective to enhance the separation efficiency. Lab-scale dead-end filtration tests were implemented and the key factors involved in the separation performances were investigated. Membrane characteristics, biomass composition, and hydrodynamic conditions were considered. Organic membranes provided adequate filtration performance. Membrane fouling was essentially induced by a rapid reversible algae deposit and to a lesser extent by irreversible pore blockage caused by smaller particles and dissolved organic matter. To cancel the reversible fouling, hydrodynamic actions such as stirring and back-flush efficiently prevented algae deposit, allowing higher filtration productivity. This study demonstrates the feasibility of membrane separation for micro-algae harvesting at laboratory-scale and specifies the suitable working conditions. (authors)

Online Recruitment: Feasibility, Cost, and Representativeness in a Study of Postpartum Women.

Science.gov (United States)

Leach, Liana S; Butterworth, Peter; Poyser, Carmel; Batterham, Philip J; Farrer, Louise M

2017-03-08

Online recruitment is feasible, low-cost, and can provide high-quality epidemiological data. However, little is known about the feasibility of recruiting postpartum women online, or sample representativeness. The current study investigates the feasibility of recruiting a population of postpartum women online for health research and examines sample representativeness. Two samples of postpartum women were compared: those recruited online as participants in a brief survey of new mothers (n=1083) and those recruited face-to-face as part of a nationally representative study (n=579). Sociodemographic, general health, and mental health characteristics were compared between the two samples. Obtaining a sample of postpartum women online for health research was highly efficient and low-cost. The online sample over-represented those who were younger (aged 25-29 years), were in a de facto relationship, had higher levels of education, spoke only English at home, and were first-time mothers. Members of the online sample were significantly more likely to have poor self-rated health and poor mental health than the nationally representative sample. Health differences remained after adjusting for sociodemographic differences. Potential exists for feasible and low-cost e-epidemiological research with postpartum populations; however, researchers should consider the potential influence of sample nonrepresentativeness. ©Liana S Leach, Peter Butterworth, Carmel Poyser, Philip J Batterham, Louise M Farrer. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 08.03.2017.

Feasibility study for Boardman River hydroelectric power. Final report

Energy Technology Data Exchange (ETDEWEB)

None

1979-02-22

The feasibility of generating additional hydroelectric power from five consecutive existing dams located on the Boardman River in Grand Traverse County and Traverse City, Michigan, was investigated. The potential hydropower production capabilities, in terms of base load power and peak load power, the legal-institutional-environmental constraints, and the economic feasibility, including capital investment, operating costs and maintenance costs, were evaluated for each of the five dam sites individually and as a series of co-dependent facilities. The impact of installing fish passages at each site was analyzed separately. The feasibility assessment utilized the present worth analytical method, considering revenue based on thirty mills/kWh for power, 0.4% general economy escalation rate, and a 6% net income to the municipal utility. The sensitivity of fuel costs increasing at a different rate than the general price-escalation was tested by allowing the increase in fuel costs to vary from 3 to 8% per year. Assuming fuel costs increase at the same rate as the general economy, it is feasible to update, retrofit, renovate, and install hydroelectric generating capacity at Sabin, Boardman and Brown Bridge. Rehabilitation of Union Street and Keystone is also feasible but somewhat less attractive. Operating the dams as a co-dependent system has environmental advantages and can provide additional revenue through peak load power rates. A development plan to implement the above is outlined utilizing an ownership arrangement whereby Grand Traverse County provides easements for Sabin and Boardman Dams. The plan calls for operation of the system by Traverse City.

A guideline to study the feasibility domain of multi-trophic and changing ecological communities.

Science.gov (United States)

Song, Chuliang; Rohr, Rudolf P; Saavedra, Serguei

2018-04-24

The feasibility domain of an ecological community can be described by the set of environmental abiotic and biotic conditions under which all co-occurring and interacting species in a given site and time can have positive abundances. Mathematically, the feasibility domain corresponds to the parameter space compatible with positive (feasible) solutions at equilibrium for all the state variables in a system under a given model of population dynamics. Under specific dynamics, the existence of a feasible equilibrium is a necessary condition for species persistence regardless of whether the feasible equilibrium is dynamically stable or not. Thus, the size of the feasibility domain can also be used as an indicator of the tolerance of a community to random environmental variations. This has motivated a rich research agenda to estimate the feasibility domain of ecological communities. However, these methodologies typically assume that species interactions are static, or that input and output energy flows on each trophic level are unconstrained. Yet, this is different to how communities behave in nature. Here, we present a step-by-step quantitative guideline providing illustrative examples, computational code, and mathematical proofs to study systematically the feasibility domain of ecological communities under changes of interspecific interactions and subject to different constraints on the trophic energy flows. This guideline covers multi-trophic communities that can be formed by any type of interspecific interactions. Importantly, we show that the relative size of the feasibility domain can significantly change as a function of the biological information taken into consideration. We believe that the availability of these methods can allow us to increase our understanding about the limits at which ecological communities may no longer tolerate further environmental perturbations, and can facilitate a stronger integration of theoretical and empirical research. Copyright �

Muon muon collider: Feasibility study

International Nuclear Information System (INIS)

1996-01-01

A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10 35 cm -2 s -1 . The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice--the authors believe--to allow them to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring which has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design

Industrial feasibility study of a spent nuclear fuel package for direct deep disposal

International Nuclear Information System (INIS)

Le Lous, K.; Loubrieu, J.; Chupeau, J.; Serpantie, J.P.; Becle, D.; Aubry, S.

2001-01-01

EDF has undertaken to study the industrial feasibility of a spent nuclear fuel package meeting direct disposal requirements. In this context, a disposal concept has been defined in which packages are cooled in place until the module is finally sealed. Indeed, one of the objectives of that disposal concept is to reduce the underground area occupied by the repository. A functional analysis has been performed within the framework of that ventilated disposal concept, taking into account the phases of the package lifetime from its conditioning until the disposal post-closure phase. An industrial feasibility study is in progress, which takes into account the functional specifications and some preliminary studies. (author)

Development and evaluation of a modified brief assertiveness training for nurses in the workplace: a single-group feasibility study.

Science.gov (United States)

Nakamura, Yohei; Yoshinaga, Naoki; Tanoue, Hiroki; Kato, Sayaka; Nakamura, Sayoko; Aoishi, Keiko; Shiraishi, Yuko

2017-01-01

Effective communication has a great impact on nurses' job satisfaction, team relationships, as well as patient care/safety. Previous studies have highlighted the various beneficial effects of enhancing communication through assertiveness training programs for nurses. However, most programs take a long time to implement; thus, briefer programs are urgently required for universal on-the-job-training in the workplace. The purpose of this feasibility study was to develop and evaluate a modified brief assertiveness training program (with cognitive techniques) for nurses in the workplace. This study was carried out as a single-group, open trial (pre-post comparison without a control group). Registered nurses and assistant nurses, working at two private psychiatric hospitals in Miyazaki Prefecture in Japan, were recruited. After enrolling in the study, participants received a program of two 90-min sessions with a 1-month interval between sessions. The primary outcome was the Rathus Assertiveness Schedule (RAS), with secondary measurements using the Brief Version of the Fear of Negative Evaluation Scale (BFNE) and the Brief Job Stress Questionnaire (BJSQ). Assessments were conducted at baseline and after a 1-month interval (pre- and post-intervention). A total of 22 participants enrolled in the study and completed the program. The mean total score on the primary outcome (RAS) significantly improved from -12.9 (SD = 17.2) to -8.6 (SD = 18.6) ( p  = 0.01). The within-group effect size at the post-intervention was Cohen's d = 0.24; this corresponds to the small effect of the program. Regarding secondary outcomes, there were no statistically significant effects on the BFNE or any of the BJSQ subscales (job-stressors, psychological distress, physical distress, worksite support, and satisfaction). This single-group feasibility study demonstrated that our modified brief assertiveness training for nurses seems feasible and may achieve a favorable outcome in improving their

Feasibility study of gamma-ray medical radiography

International Nuclear Information System (INIS)

Alyassin, Abdalmajeid M.; Maqsoud, Hamza A.; Mashat, Ahmad M.; Al-Mohr, Al-Sayed; Abdulwajid, Subhan

2013-01-01

This research explores the feasibility of using gamma-ray radiography in medical imaging. We will show that gamma-ray medical radiography has the potential to provide alternative diagnostic medical information to X-ray radiography. Approximately one Ci Am-241 radioactive source which emits mono-energetic 59.5 keV gamma rays was used. Several factors that influence the feasibility of this study were tested. They were the radiation source uniformity, image uniformity, and image quality parameters such as contrast, noise, and spatial resolution. In addition, several gamma-ray and X-ray images were acquired using humanoid phantoms. These images were recorded on computed radiography image receptors and displayed on a standard monitor. Visual assessments of these images were then conducted. The Am-241 radioactive source provided relatively uniform radiation exposure and images. Image noise and image contrast were mainly dependent on the exposure time and source size, whereas spatial resolution was dependent on source size and magnification factor. The gamma-ray humanoid phantom images were of lower quality than the X-ray images mainly due to the low radioactivity used and not enough exposure time. Nevertheless, the gamma-ray images displayed most of the main structures contained in the humanoid phantoms. Higher exposure rates and thus lower exposure times were estimated for different pure Am-241 source sizes that are hypothesized to provide high quality images similar to X-ray images. For instance, a 10 mm source size of pure Am-241 with 7 s exposure time should produce images similar in contrast and noise to X-ray images. This research paves the way for the production and usage of a highly radioactive Am-241 source with the potential to lead to the feasibility of acceptable quality medical gamma-ray radiography. - Highlights: ► Characterized the performance of gamma-ray radiography. ► Displayed medical images of humanoid phantoms using gamma radiography. ► Am-241

Feasibility of a Psychosocial Rehabilitation Intervention to Enhance the Involvement of Relatives in Cancer Rehabilitation: Pilot Study for a Randomized Controlled Trial

DEFF Research Database (Denmark)

L, Ledderer; KI, Cour; O, Mogensen

2013-01-01

. We developed an innovative rehabilitation program to be offered to the patient and a relative as a pair. Objective The aim of the present pilot study was to examine the feasibility of the intervention in a randomized controlled trial (RCT) and to evaluate the impact on quality of life. Methods...... significant difference was observed between the intervention and the control group. Pairs reported that the time of inclusion was inconvenient and that rehabilitation ought to meet their changing needs. Conclusions The pilot study showed that it may be difficult to conduct an RCT of a psychosocial...... rehabilitation intervention for pairs, and difficulties with inclusion and drop out have to be addressed. Interventions need to be carefully developed and tested before evaluating an effect in a large-scale study....

Knee ultrasound from research to real practice: a systematic literature review of adult knee ultrasound assessment feasibility studies.

Science.gov (United States)

Peltea, Alexandra; Berghea, Florian; Gudu, Tania; Ionescu, Ruxandra

2016-12-05

To identify and analyse existing data regarding knee ultrasound (US) feasibility in clinical practice. Material and methods: A systematic literature review was performed using the terms: ("knee") AND ("ultrasound" OR "ultrasonography") AND ("feasibility" OR "pilot" OR "proof of concept"). Feasibility studies regarding knee US or US aided maneuver involving knee joint, published during 2005-2015, were selected and evaluated against a complex framework constructed around mandatory key areas for feasibility studies: acceptability, demand, implementation, practicality, adaptation, integration and expansion. One hundred and fifty-nine publications were identified, of which 9 were included in the final analysis: 6 dealt with the development and implementation of novel US scores, while the rest focused on implementing MSUS in clinical practice, evaluating the usefulness of articular cartilage US assessment and the feasibility of sonography for intra-articular knee injections, respectively. Six studies quantified feasibility as time spent for the evaluation, with only two addressing areassuch as acceptability, implementation and practicality, although none of these systematically assessed all feasibility domains. Knee US feasibility is still poorly addressed; the time required for US assessment is the main area addressed. This information gap should be properly addressed in future works, in order to ensure the right place for this technique.

Feasibility study of utilizing solar furnace technology in steel making industry

Energy Technology Data Exchange (ETDEWEB)

Abbaspoursani, K. [The Faculty of Mechanical Engineering, Takestan Islamic Azad University (Iran, Islamic Republic of)], Email: a.abbaspour@tiau.ac.ir; Tofigh, A.A.; Nahang Toudeshki, S.; Hadadian, A. [Department of Energy, Materials and Energy Research Center (Iran, Islamic Republic of)], Email: Ali.A.Tofigh@gmail.com, email: toudeshki@hotmail.com, email: Arash.Hadadian@gmail.com; Farahmandpour, B. [Iranian Fuel Conservation company (Iran, Islamic Republic of)], Email: farahmandpour@gmail.com

2011-07-01

In Iran, the casting industry consumes 33.6% of electricity production, and most of this electricity is used in the melting process. Currently, scrap preheating is done using electric arc furnaces and the aim of this study is to assess the feasibility of replacing electric arc furnaces with solar furnaces. The performance of solar furnaces in the Iran Alloy Steel Company under Yazd climate conditions was studied. It was found that the solar irradiation time and solar insulation are sufficient to operate a solar furnace with the capacity to preheat 250 thousand tons per year of scrap to 500 degrees celsius. Results showed that such a furnace would decrease energy consumption by 40 GWh per year and that it would take 5 years to return the investment. This study demonstrated that operating a solar furnace in the Iran Alloy Steel Company under Yazd climate conditions is feasible and would result in economic and environmental benefits.

Pyrolysis in Groningen, Netherlands. Feasibility study on a transition coalition

International Nuclear Information System (INIS)

Siemons, R.V.

2005-01-01

Results of a study on the technical, economical and financial feasibility of a pyrolysis factory for the processing and energetic application of biomass wastes in the Dutch province Groningen are presented and discussed. Also, attention is paid to the implementation of the planned pyrolysis factory in one or more transition programmes. [nl

Technical Note: A simulation study on the feasibility of radiotherapy dose enhancement with calcium tungstate and hafnium oxide nano- and microparticles.

Science.gov (United States)

Sherck, Nicholas J; Won, You-Yeon

2017-12-01

To assess the radiotherapy dose enhancement (RDE) potential of calcium tungstate (CaWO 4 ) and hafnium oxide (HfO 2 ) nano- and microparticles (NPs). A Monte Carlo simulation study was conducted to gauge their respective RDE potentials relative to that of the broadly studied gold (Au) NP. The study was warranted due to the promising clinical and preclinical studies involving both CaWO 4 and HfO 2 NPs as RDE agents in the treatment of various types of cancers. The study provides a baseline RDE to which future experimental RDE trends can be compared to. All three materials were investigated in silico with the software Penetration and Energy Loss of Positrons and Electrons (PENELOPE 2014) developed by Francesc Salvat and distributed in the United States by the Radiation Safety Information Computational Center (RSICC) at Oak Ridge National Laboratory. The work utilizes the extensively studied Au NP as the "gold standard" for a baseline. The key metric used in the evaluation of the materials was the local dose enhancement factor (DEF loc ). An additional metric used, termed the relative enhancement ratio (RER), evaluates material performance at the same mass concentrations. The results of the study indicate that Au has the strongest RDE potential using the DEF loc metric. HfO 2 and CaWO 4 both underperformed relative to Au with lower DEF loc of 2-3 × and 4-100 ×, respectively. The computational investigation predicts the RDE performance ranking to be: Au > HfO 2 > CaWO 4 . © 2017 American Association of Physicists in Medicine.

Feasibility and Accuracy of Digitizing Edentulous Maxillectomy Defects: A Comparative Study.

Science.gov (United States)

Elbashti, Mahmoud E; Hattori, Mariko; Patzelt, Sebastian Bm; Schulze, Dirk; Sumita, Yuka I; Taniguchi, Hisashi

The aim of this study was to evaluate the feasibility and accuracy of using an intraoral scanner to digitize edentulous maxillectomy defects. A total of 20 maxillectomy models with two defect types were digitized using cone beam computed tomography. Conventional and digital impressions were made using silicone impression material and a laboratory optical scanner as well as a chairside intraoral scanner. The 3D datasets were analyzed using 3D evaluation software. Two-way analysis of variance revealed no interaction between defect types and impression methods, and the accuracy of the impression methods was significantly different (P = .0374). Digitizing edentulous maxillectomy defect models using a chairside intraoral scanner appears to be feasible and accurate.

A Partnership and Coping Enhancement Program for Couples Undergoing In Vitro Fertilization Treatment: An Intervention Study.

Science.gov (United States)

Ying, Liying; Wu, Xiangli; Wu, Lai Har; Shu, Jing; Loke, Alice Yuen

2018-02-15

This is a feasibility study to examine the effects of a partnership and coping enhancement program (PCEP) on improving the psychological well-being and marital functions of couples undergoing in vitro fertilization treatment. A total of 100 couples were recruited consecutively and assigned to a PCEP intervention group or a routine care control group. The couples in the PCEP group received an additional face-to-face, couple-based, 90-minute session on enhancing partnership and coping on the day of the embryo transfer (ET). The outcome measures were assessed at baseline (T0), 10 days after the ET (T1), and one month after the ET (T2). The level of anxiety of the women was lower in the intervention than in the control group at T1. Significant improvements in partnership and dyadic coping were seen in women at T2. The men of infertile couples reported a significant improvement in the scores for partnership at T2. The PCEP had no significant effects on marital satisfaction and marital adjustment for both the females and males of the infertile couples. The findings indicated that the PCEP is feasible and acceptable. Before a larger simple-size randomized controlled trial with participants drawn from multiple reproductive medical centers is conducted to further confirm its effectiveness.

Improving fatigue in multiple sclerosis by smartphone-supported energy management: The MS TeleCoach feasibility study.

Science.gov (United States)

D'hooghe, Marie; Van Gassen, Geert; Kos, Daphne; Bouquiaux, Olivier; Cambron, Melissa; Decoo, Danny; Lysandropoulos, Andreas; Van Wijmeersch, Bart; Willekens, Barbara; Penner, Iris-Katharina; Nagels, Guy

2018-03-27

Fatigue is a frequently occurring, often disabling symptom in MS with no single effective treatment. In current fatigue management interventions, personalized, real-time follow-up is often lacking. The objective of the study is to assess the feasibility of the MS TeleCoach, a novel intervention offering telemonitoring of fatigue and telecoaching of physical activity and energy management in persons with MS (pwMS) over a 12-week period. The goal of the MS TeleCoach, conceived as a combination of monitoring, self-management and motivational messages, is to enhance levels of physical activity thereby improving fatigue in pwMS in an accessible and interactive way, reinforcing self-management of patients. We conducted a prospective, open-label feasibility study of the MS TeleCoach in pwMS with Expanded Disability Status Scale ≤ 4 and moderate to severe fatigue as measured by the Fatigue Scale for Motor and Cognitive Functions (FSMC). Following a 2-week run-in period to assess the baseline activity level per patient, the target number of activity counts was gradually increased over the 12-week period through telecoaching. The primary efficacy outcome was change in FSMC total score from baseline to study end. A subset of patients was asked to fill in D-QUEST 2.0, a usability questionnaire, to evaluate the satisfaction with the MS TeleCoach device and the experienced service. Seventy-five patients were recruited from 16 centres in Belgium, of which 57 patients (76%) completed the study. FSMC total score (p = 0.009) and motor and cognitive subscores (p = 0.007 and p = 0.02 respectively) decreased from baseline to week 12, indicating an improvement in fatigue. One third of participants with severe fatigue changed to a lower FSMC category for both FSMC total score and subscores. The post-study evaluation of patient satisfaction showed that the intervention was well accepted and that patients were very satisfied with the quality of the professional services

ADHD and EEG-neurofeedback: a double-blind randomized placebo-controlled feasibility study

NARCIS (Netherlands)

Lansbergen, M.M.; Dongen-Boomsma, M. van; Buitelaar, J.K.; Slaats-Willemse, D.I.E.

2011-01-01

Electroencephalography (EEG)-neurofeedback has been shown to offer therapeutic benefits to patients with attention-deficit/hyperactivity disorder (ADHD) in several, mostly uncontrolled studies. This pilot study is designed to test the feasibility and safety of using a double-blind placebo

Trans-Caspian gas pipeline feasibility study. Volume 3

International Nuclear Information System (INIS)

1999-01-01

This study, conducted by Enron Engineering and Construction Company, was funded by the US Trade and Development Agency. The study provides detailed information concerning natural gas demand in Turkey and Southern Europe. The purpose of the study is to estimate the rate at which new gas can be absorbed in the Turkish market and be re-exported to the markets in Europe, as well as to forecast Turkish natural gas demand for the period up to 2020. The study also evaluates gas demand and pricing for the market in the 2002--2005 time frame. This is Volume 3 of a 3-volume report, and it is divided into the following sections: (1) Executive Summary; (2) Task C: Technical Feasibility and Preliminary Design; (3) Task F: Project Implementation Strategy

Feasibility study report for Operable Unit 4: Volume 2

International Nuclear Information System (INIS)

1994-02-01

This report documents the Feasibility Study (FS) phase of the Fernald Environmental Management Project (FEMP) Operable Unit 4 Remedial Investigation/Feasibility Study (RI/FS) Program. The FEMP, formerly known as the Feed Materials Production Center (FMPC), is a US Department of Energy (DOE) facility that operated from 1952 to 1989. The facility's primarily function was to provide high purity uranium metal products to support United States defense programs. Production operations were suspended in 1989 to focus on environmental restoration and waste management activities at the facility. The RI/FS is being conducted pursuant to the terms of a Consent Agreement between DOE and the US Environmental Protection Agency (EPA) under Sections 120 and 106(a) of the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA), as amended. The Ohio Environmental Protection Agency (OEPA) is also participating in the RI/FS process at the FEMP through direct involvement in program review meetings and technical review of project documentation. The objective of the RI/FS process is to gather information to support an informed risk management decision regarding which remedy appears to be the most appropriate action for addressing the environmental concerns identified at the FEMP. This volume contains appendices A--E

Feasibility Study for Cobalt Bundle Loading to CANDU Reactor Core

International Nuclear Information System (INIS)

Park, Donghwan; Kim, Youngae; Kim, Sungmin

2016-01-01

CANDU units are generally used to produce cobalt-60 at Bruce and Point Lepreau in Canada and Embalse in Argentina. China has started production of cobalt-60 using its CANDU 6 Qinshan Phase III nuclear power plant in 2009. For cobalt-60 production, the reactor’s full complement of stainless steel adjusters is replaced with neutronically equivalent cobalt-59 adjusters, which are essentially invisible to reactor operation. With its very high neutron flux and optimized fuel burn-up, the CANDU has a very high cobalt-60 production rate in a relatively short time. This makes CANDU an excellent vehicle for bulk cobalt-60 production. Several studies have been performed to produce cobalt-60 using adjuster rod at Wolsong nuclear power plant. This study proposed new concept for producing cobalt-60 and performed the feasibility study. Bundle typed cobalt loading concept is proposed and evaluated the feasibility to fuel management without physics and system design change. The requirement to load cobalt bundle to the core was considered and several channels are nominated. The production of cobalt-60 source is very depend on the flux level and burnup directly. But the neutron absorption characteristic of cobalt bundle is too high, so optimizing design study is needed in the future

Feasibility Study for Cobalt Bundle Loading to CANDU Reactor Core

Energy Technology Data Exchange (ETDEWEB)

Park, Donghwan; Kim, Youngae; Kim, Sungmin [KHNP Central Research Institute, Daejeon (Korea, Republic of)

2016-10-15

CANDU units are generally used to produce cobalt-60 at Bruce and Point Lepreau in Canada and Embalse in Argentina. China has started production of cobalt-60 using its CANDU 6 Qinshan Phase III nuclear power plant in 2009. For cobalt-60 production, the reactor’s full complement of stainless steel adjusters is replaced with neutronically equivalent cobalt-59 adjusters, which are essentially invisible to reactor operation. With its very high neutron flux and optimized fuel burn-up, the CANDU has a very high cobalt-60 production rate in a relatively short time. This makes CANDU an excellent vehicle for bulk cobalt-60 production. Several studies have been performed to produce cobalt-60 using adjuster rod at Wolsong nuclear power plant. This study proposed new concept for producing cobalt-60 and performed the feasibility study. Bundle typed cobalt loading concept is proposed and evaluated the feasibility to fuel management without physics and system design change. The requirement to load cobalt bundle to the core was considered and several channels are nominated. The production of cobalt-60 source is very depend on the flux level and burnup directly. But the neutron absorption characteristic of cobalt bundle is too high, so optimizing design study is needed in the future.

Feasibility studies of radiation sterilization of some pharmaceutical products

International Nuclear Information System (INIS)

Gopal, N.G.S.; Rajagopalan, S.; Sharma, G.

1975-01-01

The paper deals with some studies carried out to evaluate the feasibility of radiation sterilization or treatment of some medical products and pharmaceuticals of immediate importance to their respective industries. The products include penicillin G sodium, ampicillin sodium, tetracyclin hydrochloride ointment,hydrocortisone acetate and its ointment, aqueous sodium chloride solutions (0.9 and 20%), fluorescein sodium strips, urea, ethylmorphine hydrochloride, aqueous solution of chlorobutanol and one of its commercial preparations, phenylmercuric nitrate and its aqueous solutions, aqueous solutions of methyl and propyl paraben, lactose, gum karaya, absorbent cotton and poly-(vinyl chloride) based medical products. The irradiated products have been examined for pharmacopoeial specifications wherever available. In general the products have been examined for changes in colour, pH, ultra-violet and infra-red absorption spectra. Thin-layer chromatographic analyses have been carried out to establish the purity of some of the irradiated products. The feasibility or otherwise of radiation sterilization or treatment of the various products from the physicochemical and microbiological (pharmacological) clinical considerations is also described. (author)

Recruitment and retention of farm owners and workers for a six-month prospective injury study in New Zealand: a feasibility study

Directory of Open Access Journals (Sweden)

Langley John D

2011-05-01

Full Text Available Abstract Background Agricultural workers experience high rates of occupational injury. There is a lack of analytic studies which provide detailed occupational exposure information to inform intervention development. Methods A feasibility study simulating a six month prospective cohort study was designed and undertaken. The levels of farm and worker participation and retention were analysed to determine the feasibility of the methods for wider deployment. Results Recruitment levels were comparable with other studies, with 24% of farms and 36% of non-owner workers participating. Once recruited, retention was high at 85% and 86% respectively. Conclusions The main challenges identified were in the recruitment process. Once recruited, farms and workers tended to complete the study, indicating that prospective studies in this the agricultural workforce may be feasible. Issues encountered and potential solutions for future studies are discussed.

Small modular biopower initiative Phase 1 feasibility studies executive summaries

Energy Technology Data Exchange (ETDEWEB)

Bain, R.

2000-03-06

The Phase 1 objective is a feasibility study that includes a market assessment, resource assessment, preliminary system design, and assessment of relevant environmental and safety considerations, and evaluation of financial and cost issues, and a preliminary business plan and commercialization strategy. Each participating company will share at least 20% of the cost of the first phase.

Pueblo of Jemez Geothermal Feasibility Study Fianl Report

Energy Technology Data Exchange (ETDEWEB)

S.A. Kelley; N. Rogers; S. Sandberg; J. Witcher; J. Whittier

2005-03-31

This project assessed the feasibility of developing geothermal energy on the Pueblo of Jemez, with particular attention to the Red Rocks area. Geologic mapping of the Red Rocks area was done at a scale of 1:6000 and geophysical surveys identified a potential drilling target at a depth of 420 feet. The most feasible business identified to use geothermal energy on the reservation was a greenhouse growing culinary and medicinal herbs. Space heating and a spa were identified as two other likely uses of geothermal energy at Jemez Pueblo. Further geophysical surveys are needed to identify the depth to the Madera Limestone, the most likely host for a major geothermal reservoir.

Biogas Koczala. Biogas project in Koczala. Feasibility study. Technical report

International Nuclear Information System (INIS)

2004-08-01

The present production of district heating in Koczala is based on coal. The district heating system is worn out technically and economically and according to the 2001 Energy Plan of Koczala the district heating plant shall be converted to a combination of a biogas fired CHP and a wood chip boiler. The overall objective of this project is to access the feasibility and viability construction an operation of a biogas plant owned by the co-operative agricultural company, Poldanor S.A. The feasibility study includes: 1) Availability of organic waste in the Koczala area, 2) Possibilities of using energy crops in the biogas plant, 3) Possibilities of receiving grants from the Polish National Fund for Environmental Protection, the new EU regional funds and through the joint implementation market (CO 2 quotas), 4) Alternative locations of the biogas plant and the CHP unit, 5) Alternative strategies for selling electricity and heat, 6) Organisational issues (ownership). This report concludes that implementing the biogas project is environmentally and financially feasible and viable. If organic waste and/or maize silage can be provided and gasified without problems, the plant can supply as well the Koczala farm as the fodder mill with steam and heat, and also supply Koczala district heating system with approx. 75% of yearly heat consumption. Furthermore, electricity is supplied to the fodder mill and the public grid. (BA)

Report of year 2000 version on feasibility study. Feasibility study on the diffusion of fluidized bed cement kiln system in Socialist Republic of Viet Nam

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

Evaluations were given on the possibility of saving energies and reducing CO2 emission by renewing the shaft kilns operated in four factories in Viet Nam into fluidized bed kilns. The feasibility study is intended to be linked to the clean development mechanism (CDM) in the future. The fluidized bed kiln is a most advanced technology developed to deal with social, economic and technological demands such as global environment preservation, energy conservation, effective utilization of resources, enhancement of economic performance, and diversification of cement needs. The technology is capable of largely reducing greenhouse effect gases, eliminating the problem of dust scattering from sintering facilities, producing stabilized and high-quality clinker, making possible of using inexpensive fuels including low-order coal, using less installation space, and reducing the production cost. The amount of energy reduction in all of the four factories is calculated 8,101 to 9,551 toe/year at an energy saving effect rate of 37 to 44%. CO2 emission is reduced as a result of reduction in fuel for sintering furnaces and in electric power consumption. The reduction amount would be 24,393 to 38,794 tons/year (converted into CO2), and the reduction effect rate would be 36 to 44%. The investment effect looks sufficient as payout of 10 to 12 years if the environment special Yen loan is used. Trial calculation was also performed for the nation-wide proliferation effect. (NEDO)

Technical and economic feasibility study of enhanced oil recovery in six Colombian fields. Appendix C. Export trade information

Energy Technology Data Exchange (ETDEWEB)

1986-09-01

The primary objectives of the study were to determine which of the reservoirs in the principal fields were amenable to enhanced oil recovery (EOR) processes, to evaluate which process was the most effective from both a technical and economic point of view, and to propose the steps required to further investigate the recommended EOR methods at the laboratory and field (pilot) level. Appendix C is divided into three sections: (A) Casabe Field; (B) La Cira Field; and (C) Tibu-Barco.

Current status of feasibility studies on commercialized fuel cycle system for Fast Breeder Reactor

International Nuclear Information System (INIS)

Ojima, Hisao; Nagaoki, Yoshihiro

2000-01-01

A 'Feasibility Studies on Commercialized Fast Breeder Reactor Cycle System' is underway at the Japan Nuclear Cycle Development Institute (JNC). The study will select the promising concepts with their R and D tasks in order to commercialize the fast breeder reactor (FBR) cycle system. The feasibility studies (F/S) have to present surveyed and screened various relevant technologies, and defined the design requirement of the commercialized fuel cycle system for FBR. The promising technical options are being evaluated and conceptual designs are being examined. At the end of JFY2000, several candidate concepts of the commercialized FBR cycle system will be proposed. (author)

Muon muon collider: Feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-06-18

A feasibility study is presented of a 2 + 2 TeV muon collider with a luminosity of L = 10{sup 35} cm{sup {minus}2} s{sup {minus}1}. The resulting design is not optimized for performance, and certainly not for cost; however, it does suffice--the authors believe--to allow them to make a credible case, that a muon collider is a serious possibility for particle physics and, therefore, worthy of R and D support so that the reality of, and interest in, a muon collider can be better assayed. The goal of this support would be to completely assess the physics potential and to evaluate the cost and development of the necessary technology. The muon collider complex consists of components which first produce copious pions, then capture the pions and the resulting muons from their decay; this is followed by an ionization cooling channel to reduce the longitudinal and transverse emittance of the muon beam. The next stage is to accelerate the muons and, finally, inject them into a collider ring which has a small beta function at the colliding point. This is the first attempt at a point design and it will require further study and optimization. Experimental work will be needed to verify the validity of diverse crucial elements in the design.

Sealed source and device removal and consolidation feasibility study

International Nuclear Information System (INIS)

Ward, J.E.; Carter, J.G.; Meyers, R.L.

1993-02-01

The purpose of this study is to assess the feasibility of removing Greater-Than-Class C (GTCC) sealed sources from their containment device and consolidating them for transport to a storage or disposal facility. A sealed source is a sealed capsule containing a radioactive material that is placed in a device providing radioactive containment. It is used in the medical, industrial, research, and food-processing communities for calibrating, measuring, gauging, controlling processes, and testing. This feasibility study addresses the key operational, safety, regulatory, and financial requirements of the removal/consolidation process. This report discusses the process to receive, handle, repackage, and ship these sources to an interim or dedicated storage facility until a final disposal repository can be built and become operational (∼ c. 2010). The study identifies operational and facility requirements to perform this work. Hanford, other DOE facilities, and private hot-cell facilities were evaluated to determine which facilities could perform this work. The personnel needed, design and engineering, facility preparation, process waste disposal requirements, and regulatory compliance were evaluated to determine the cost to perform this work. Cost requirements for items that will have to meet future changing regulatory requirements for transportation, transportation container design and engineering, and disposal were not included in this study. The cost associated with in-process consolidation of the sealed sources reported in this study may have not been modified for inflation and were based on 1992 dollars. This study shows that sealed source consolidation is possible with minimal personnel exposure, and would reduce the risk of radioactive releases to the environment. An initial pilot-scale operation could evaluate the possible methods to reduce the cost and consolidate sources

Feasibility studies for alpha waste disposal on geological formations in France

International Nuclear Information System (INIS)

Jaouen, C.; Boulanger, A.

1986-01-01

Since 1977, SGN has been involved in many feasibility studies and consultant works in the fields of HLW storages. Starting as nuclear consultant company in the KBS review of the long term storage of HLW, SGN and GEOSTOCK were entrusted in 1978 by the EEC for the basic design and evaluation of the deep storage into granite rock of HLW, followed by a participation in the thermal sensitivity study of such a storage. The cooperation with GEOSTOCK was first extended in 1981 to a preliminary study of HLW storage conditions in granite for a Japanese company, and then in France for several feasibility studies of HLW and TRU waste geological disposal. Three kinds of scenarios have been forecasted and evaluated in the case of vitrified HLW storage, allowing the thermal power to be decreased and the whole management scheme to be optimized. More recently, SGN participation to French engineering studies has been extended by ANDRA to the TRU waste repository evaluation. All these works for French authorities have been performed in a close connection with several specialized departments in the CEA group, and with the help of geological specialists, under the leadership of ANDRA [fr

Feasibility studies for alpha waste disposal on geological formations in France

International Nuclear Information System (INIS)

Jaouen, C.; Boulanger, A.

1985-01-01

Since 1977, SGN has been involved in many feasibility studies and consultant works in the fields of HLW storages. Starting as nuclear consultant company in the KBS review of the long term storage of HLW, SGN and Geostock were entrusted in 1978 by the EEC for the basic design and evaluation of the deep storage into granite rock of HLW, followed by a participation in the thermal sensitivity study of such a storage. The cooperation with Geostock was first extended in 1981 to a preliminary study of HLW storage conditions in granite for a Japanese company, and then in France for several feasibility studies of HLW and TRU waste geological disposal. Three kinds of scenarios have been forecasted and evaluated in the case of vitrified HLW storage, allowing the thermal power to be decreased and the whole management scheme to be optimized. More recently, SGN participation to French engineering studies has been extended by ANDRA to the TRU waste repository evaluation. All these works for French authorities have been performed in a close connection with several specialized departments in the CEA group, and with the help of geological specialists, under the leadership of ANDRA [fr

Regulation of Romantic Love Feelings: Preconceptions, Strategies, and Feasibility.

Science.gov (United States)

Langeslag, Sandra J E; van Strien, Jan W

2016-01-01

Love feelings can be more intense than desired (e.g., after a break-up) or less intense than desired (e.g., in long-term relationships). If only we could control our love feelings! We present the concept of explicit love regulation, which we define as the use of behavioral and cognitive strategies to change the intensity of current feelings of romantic love. We present the first two studies on preconceptions about, strategies for, and the feasibility of love regulation. Questionnaire responses showed that people perceive love feelings as somewhat uncontrollable. Still, in four open questions people reported to use strategies such as cognitive reappraisal, distraction, avoidance, and undertaking (new) activities to cope with break-ups, to maintain long-term relationships, and to regulate love feelings. Instructed up-regulation of love using reappraisal increased subjective feelings of attachment, while love down-regulation decreased subjective feelings of infatuation and attachment. We used the late positive potential (LPP) amplitude as an objective index of regulation success. Instructed love up-regulation enhanced the LPP between 300-400 ms in participants who were involved in a relationship and in participants who had recently experienced a romantic break-up, while love down-regulation reduced the LPP between 700-3000 ms in participants who were involved in a relationship. These findings corroborate the self-reported feasibility of love regulation, although they are complicated by the finding that love up-regulation also reduced the LPP between 700-3000 ms in participants who were involved in a relationship. To conclude, although people have the preconception that love feelings are uncontrollable, we show for the first time that intentional regulation of love feelings using reappraisal, and perhaps other strategies, is feasible. Love regulation will benefit individuals and society because it could enhance positive effects and reduce negative effects of romantic

Regulation of Romantic Love Feelings: Preconceptions, Strategies, and Feasibility

Science.gov (United States)

Langeslag, Sandra J. E.; van Strien, Jan W.

2016-01-01

Love feelings can be more intense than desired (e.g., after a break-up) or less intense than desired (e.g., in long-term relationships). If only we could control our love feelings! We present the concept of explicit love regulation, which we define as the use of behavioral and cognitive strategies to change the intensity of current feelings of romantic love. We present the first two studies on preconceptions about, strategies for, and the feasibility of love regulation. Questionnaire responses showed that people perceive love feelings as somewhat uncontrollable. Still, in four open questions people reported to use strategies such as cognitive reappraisal, distraction, avoidance, and undertaking (new) activities to cope with break-ups, to maintain long-term relationships, and to regulate love feelings. Instructed up-regulation of love using reappraisal increased subjective feelings of attachment, while love down-regulation decreased subjective feelings of infatuation and attachment. We used the late positive potential (LPP) amplitude as an objective index of regulation success. Instructed love up-regulation enhanced the LPP between 300–400 ms in participants who were involved in a relationship and in participants who had recently experienced a romantic break-up, while love down-regulation reduced the LPP between 700–3000 ms in participants who were involved in a relationship. These findings corroborate the self-reported feasibility of love regulation, although they are complicated by the finding that love up-regulation also reduced the LPP between 700–3000 ms in participants who were involved in a relationship. To conclude, although people have the preconception that love feelings are uncontrollable, we show for the first time that intentional regulation of love feelings using reappraisal, and perhaps other strategies, is feasible. Love regulation will benefit individuals and society because it could enhance positive effects and reduce negative effects of

Regulation of Romantic Love Feelings: Preconceptions, Strategies, and Feasibility.

Directory of Open Access Journals (Sweden)

Sandra J E Langeslag

Full Text Available Love feelings can be more intense than desired (e.g., after a break-up or less intense than desired (e.g., in long-term relationships. If only we could control our love feelings! We present the concept of explicit love regulation, which we define as the use of behavioral and cognitive strategies to change the intensity of current feelings of romantic love. We present the first two studies on preconceptions about, strategies for, and the feasibility of love regulation. Questionnaire responses showed that people perceive love feelings as somewhat uncontrollable. Still, in four open questions people reported to use strategies such as cognitive reappraisal, distraction, avoidance, and undertaking (new activities to cope with break-ups, to maintain long-term relationships, and to regulate love feelings. Instructed up-regulation of love using reappraisal increased subjective feelings of attachment, while love down-regulation decreased subjective feelings of infatuation and attachment. We used the late positive potential (LPP amplitude as an objective index of regulation success. Instructed love up-regulation enhanced the LPP between 300-400 ms in participants who were involved in a relationship and in participants who had recently experienced a romantic break-up, while love down-regulation reduced the LPP between 700-3000 ms in participants who were involved in a relationship. These findings corroborate the self-reported feasibility of love regulation, although they are complicated by the finding that love up-regulation also reduced the LPP between 700-3000 ms in participants who were involved in a relationship. To conclude, although people have the preconception that love feelings are uncontrollable, we show for the first time that intentional regulation of love feelings using reappraisal, and perhaps other strategies, is feasible. Love regulation will benefit individuals and society because it could enhance positive effects and reduce negative

Gray-scale contrast-enhanced utrasonography in detecting sentinel lymph nodes: An animal study

International Nuclear Information System (INIS)

Wang Yuexiang; Cheng Zhigang; Li Junlai; Tang Jie

2010-01-01

Objective: To investigate the usefulness of gray-scale contrast-enhanced ultrasonography for detecting sentinel lymph nodes. Methods: Contrast-enhanced ultrasonography was performed in five normal dogs (four female and one male) after subcutaneous administration of a sonographic contrast agent (Sonovue, Bracco, Milan, Italy). Four distinct regions in each animal were examined. After contrast-enhanced ultrasonography, 0.8 ml of blue dye was injected into the same location as Sonovue and the sentinel lymph nodes were detected by surgical dissection. The findings of contrast-enhanced ultrasonography were compared with those of the blue dye. Results: Twenty-one sentinel lymph nodes were detected by contrast-enhanced ultrasonography while 23 were identified by blue dye with surgical dissection. Compared with the blue dye, the detection rate of enhanced ultrasonography for the sentinel lymph nodes is 91.3% (21/23). Two patterns of enhancement in the sentinel lymph nodes were observed: complete enhancement (5 sentinel lymph nodes) and partial enhancement (16 sentinel lymph nodes). The lymphatic channels were demonstrated as hyperechoic linear structures leading from the injection site and could be readily followed to their sentinel lymph nodes. Histopathologic examination showed proliferation of lymphatic follicles or lymphatic sinus in partial enhanced sentinel lymph nodes while normal lymphatic tissue was demonstrated in completely enhanced sentinel lymph nodes. Conclusions: Sonovue combined with gray-scale contrast-enhanced ultrasonography may provide a feasible method for detecting sentinel lymph nodes.

Application of surfactant enhanced permanganate oxidation and bidegradation of trichloroethylene in groundwater

Energy Technology Data Exchange (ETDEWEB)

Tsai, T.T.; Kao, C.M. [Institute of Environmental Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan (China); Yeh, T.Y. [Department of Civil and Environmental Engineering, National University of Kaohsiung, Kaohsiung, Taiwan (China)], E-mail: tyyeh@nuk.edu.tw; Liang, S.H.; Chien, H.Y. [Institute of Environmental Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan (China)

2009-01-15

The industrial solvent trichloroethylene (TCE) is among the most ubiquitous chlorinated solvents found in groundwater contamination. The main objectives of this study were to evaluate the feasibility of using non-ionic surfactant Simple Green{sup TM} (SG) to enhance the oxidative dechlorination of TCE by potassium permanganate (KMnO{sub 4}) employing a continuous stir batch reactor system (CSBR) and column experiments. The effect of using surfactant SG to enhance the biodegradation of TCE via aerobic cometabolism was also examined. Results from CSBR experiments revealed that combination of KMnO{sub 4} with surfactant SG significantly enhanced contaminant removal, particularly when the surfactant SG concentrated at its CMC. TCE degradation rates ranged from 74.1% to 85.7% without addition of surfactant SG while TCE degradation rates increased to ranging from 83.8% to 96.3% with presence of 0.1 wt% SG. Furthermore, results from column experiments showed that TCE was degraded from 38.1 {mu}M to 6.2 {mu}M in equivalent to 83.7% of TCE oxidation during first 560 min reaction. This study has also demonstrated that the addition of surfactant SG is a feasible method to enhance bioremediation efficiency for TCE contaminated groundwater. The complete TCE degradation was detected after 75 days of incubation with both 0.01 and 0.1 wt% of surfactant SG addition. Results revealed that surfactant enhanced chemical oxidation and bioremediation technology is one of feasible approaches to clean up TCE contaminated groundwater.

Technical Feasibility Study for Zero Energy K-12 Schools

Energy Technology Data Exchange (ETDEWEB)

Bonnema, Eric [National Renewable Energy Lab. (NREL), Golden, CO (United States); Goldwasser, David [National Renewable Energy Lab. (NREL), Golden, CO (United States); Torcellini, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Shanti [National Renewable Energy Lab. (NREL), Golden, CO (United States); Studer, Daniel [National Renewable Energy Lab. (NREL), Golden, CO (United States)

2016-11-01

This technical feasibility study provides documentation and research results supporting a possible set of strategies to achieve source zero energy K-12 school buildings as defined by the U.S. Department of Energy (DOE) zero energy building (ZEB) definition (DOE 2015a). Under this definition, a ZEB is an energy-efficient building in which, on a source energy basis, the actual annual delivered energy is less than or equal to the on-site renewable exported energy.

Pascua Yaqui Tribe Renewable Energy Development and Deployment Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Arvayo, Maria

2014-05-30

In 2012, PYT was awarded a grant from the Department of Energy Tribal Energy Program to conduct a Renewable Energy Development and Deployment Feasibility Study that would define the technical and economic viability of renewable energy on tribal lands. Red Mountain Energy Partners (RMEP) was hired by PYT to complete the study. Through this study, Red Mountain concluded that there are viable opportunities for solar at Tortuga Ranch, the Casino del Sol and a third site near the Justice Center on Camino de Oeste.

Photon-phonon laser on crystalline silicon: a feasibility study

International Nuclear Information System (INIS)

Zadernovsky, A A

2015-01-01

We discuss a feasibility of photon-phonon laser action in bulk silicon with electron population inversion. It is well known, that only direct gap semiconductors are used as an active medium in optical lasers. In indirect gap semiconductors, such as crystalline silicon, the near-to-gap radiative electron transitions must be assisted by emission or absorption of phonons to conserve the momentum. The rate of such two-quantum transitions is much less than in direct gap semiconductors, where the similar radiative transitions are single-quantum. As a result, the quantum efficiency of luminescence in silicon is too small to get it as a laser material. Numerous proposals to overcome this problem are aimed at increasing the rate of radiative recombination. We suggest enhancing the quantum efficiency of luminescence in silicon by stimulating the photon part of the two-quantum transitions by light from an appropriate external laser source. This allows us to obtain initially an external-source-assisted lasing in silicon and then a true photon-phonon lasing without any external source of radiation. Performed analysis revealed a number of requirements to the silicon laser medium (temperature, purity and perfection of crystals) and to the intensity of stimulating radiation. We discuss different mechanisms that may hinder the implementation of photon-phonon lasing in silicon

3D-Flow processor for a programmable Level-1 trigger (feasibility study)

International Nuclear Information System (INIS)

Crosetto, D.

1992-10-01

A feasibility study has been made to use the 3D-Flow processor in a pipelined programmable parallel processing architecture to identify particles such as electrons, jets, muons, etc., in high-energy physics experiments

Kundalini yoga as mutual recovery: a feasibility study including children in care and their carers

OpenAIRE

Perez, Elvira; Ball, Mark; Brown, Poppy; Crepaz-Keay, David; Haslam-Jones, Emily; Crawford, Paul

2016-01-01

This is a mixed-methods feasibility study to test whether incorporating a 20-week Kundalini yoga program into a children’s home community improves wellbeing outcomes. Feasibility was assessed through recruitment and retention rates as well as participants’ self-report perceptions on social inclusion, mental health, wellbeing and semi-structured interviews on the benefits of the study. Mutual recovery entailed that children in care (CiC), youth practitioners, and management participated togeth...

A feasibility study of magnetic resonance imaging of silicone breast implants in Finland

DEFF Research Database (Denmark)

Kulmala, Ilona; Boice, John D; McLaughlin, Joseph K

2005-01-01

to determine the feasibility of conducting a magnetic resonance imaging (MRI)-based study of rupture incidence. The pilot investigation included a clinical examination by a plastic surgeon, MRI scan, and self-administered questionnaire. The participation rate was 100%. Implants in our study represented a cross...... the other diagnosed all implants as intact. The procedures of the feasibility study proved successful, and the results demonstrate the importance of a rigid image evaluation protocol with employment of well-defined rupture criteria, as well as the benefits of several image readers.......Cosmetic breast implants have become increasingly popular throughout the world. However, there is insufficient knowledge about the frequency and severity of local complications such as rupture and capsular contracture. A pilot study of 25 Finnish women with 50 cosmetic breast implants was organized...

Feasibility Study for Operable Unit 7-13/14

International Nuclear Information System (INIS)

K. Jean Holdren Thomas E. Bechtold Brian D. Preussner

2007-01-01

The Subsurface Disposal Area is a radioactive waste landfill located within the Radioactive Waste Management Complex at the Idaho National Laboratory Site in southeastern Idaho. This Feasibility Study for Operable Unit 7-13/14 analyzes options for mitigating risks to human health and the environment associated with the landfill. Analysis is conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act, using nine evaluation criteria to develop detailed and comparative analysis of five assembled alternatives. Assembled alternatives are composed of discrete modules. Ultimately, decision-makers will select, recombine, and sum various modules into an optimized preferred alternative and final remedial decision

Feasibility Study for Operable Unit 7-13/14

Energy Technology Data Exchange (ETDEWEB)

K. Jean Holdren

2007-05-29

The Subsurface Disposal Area is a radioactive waste landfill located within the Radioactive Waste Management Complex at the Idaho National Laboratory Site in southeastern Idaho. This Feasibility Study for Operable Unit 7-13/14 analyzes options for mitigating risks to human health and the environment associated with the landfill. Analysis is conducted in accordance with the Comprehensive Environmental Response, Compensation, and Liability Act, using nine evaluation criteria to develop detailed and comparative analysis of five assembled alternatives. Assembled alternatives are composed of discrete modules. Ultimately, decision-makers will select, recombine, and sum various modules into an optimized preferred alternative and final remedial decision.

The PHARMS (Patient Held Active Record of Medication Status) feasibility study: a research proposal.

LENUS (Irish Health Repository)

Walsh, Elaine

2018-01-08

Medication errors are a major source of preventable morbidity, mortality and cost and many occur at the times of hospital admission and discharge. Novel interventions (such as new methods of recording medication information and conducting medication reconciliation) are required to facilitate accurate transfer of medication information. With existing evidence supporting the use of information technology and the patient representing the one constant in the care process, an electronic patient held medication record may provide a solution. This study will assess the feasibility of introducing a patient held electronic medication record in primary and secondary care using the Consolidated Framework for Implementation Research (CFIR).This feasibility study is a mixed method study of community dwelling older adult patients admitted to an urban secondary care facility comprising a non-randomised intervention and qualitative interviews with key stakeholders. Outcomes of interest include clinical outcomes and process evaluation.This study will yield insights pertaining to feasibility, acceptability and participation for a more definitive evaluation of the intervention. The study also has the potential to contribute to knowledge of implementation of technology in a healthcare context and to the broader area of implementation science.

Developing a Hypnotic Relaxation Intervention to Improve Body Image: A Feasibility Study.

Science.gov (United States)

Cieslak, Alison; Elkins, Gary; Banerjee, Tanima; Marsack, Jessica; Hickman, Kimberly; Johnson, Alisa; Henry, Norah; Barton, Debra

2016-11-01

To determine the content, feasibility, and best outcome of a mind-body intervention involving self-directed hypnotic relaxation to target body image.
. A five-week, uncontrolled, unblinded feasibility intervention study.
. Behavioral therapy offices in Ann Arbor, Michigan, and Waco, Texas.
. 10 female breast cancer survivors and 1 breast and gynecologic cancer survivor. 
. Adult women with a history of breast and gynecologic cancer and no major psychiatric history were eligible. The intervention included four face-to-face sessions with a research therapist lasting 40-60 minutes, logged home practice, one telephone check-in call at week 5, and one intervention feedback telephone call to complete the study. Descriptive statistics and paired t-tests were used to test feasibility and content validity.
. Stress from body changes as measured by the Impact of Treatment Scale, sexual function as measured by the Female Sexual Function Index, and sexual self-image as measured by the Sexual Self-Schema Scale for women were the variables of interest.
. The intervention content was confirmed. Changes in scores from the baseline to week 5 suggested that stress from body changes decreased and sexual self-schema and function improved during the intervention. Nine of the 11 women were satisfied with the intervention, and all 11 indicated that their body image improved. 
. Hypnotic relaxation therapy shows promise for improving body image and, in doing so, improving sexual health in this population. Additional testing of this intervention is warranted.
. Hypnotic relaxation therapy is feasible to improve body image and sexual health in women diagnosed with cancer and may be an important intervention that could be offered by nurses and other behavioral therapists.

Feasibility study--computerized application of the hazardous material regulations

International Nuclear Information System (INIS)

Ferrada, J.J.; Green, V.M.; Rawl, R.R.

1992-09-01

The feasibility of developing a full expert system for transportation and packaging of hazardous and radioactive materials was initiated within the framework of three subtasks: (1) analysis of commercial packages related to regulation scanning, (2) analysis of computer languages to develop the expert system, and (3) development of expert system prototypes. The strategy to develop the latter subtask was to first,develop modules to capture the knowledge of different areas of transportation and packaging and second, to analyze the feasibility of appending these different modules in one final full package. The individual modules development contemplated one prototype for transporting and packaging of radioactive material and another for transporting hazardous chemical materials. In the event that it is not feasible to link these two packages, the modules can always be used as stand-alone tools, or linked as a single package with some restrictions in their applicability. The work done during this fiscal year has focused on developing a prototype for transporting radioactive materials

da Vinci robot-assisted keyhole neurosurgery: a cadaver study on feasibility and safety.

Science.gov (United States)

Marcus, Hani J; Hughes-Hallett, Archie; Cundy, Thomas P; Yang, Guang-Zhong; Darzi, Ara; Nandi, Dipankar

2015-04-01

The goal of this cadaver study was to evaluate the feasibility and safety of da Vinci robot-assisted keyhole neurosurgery. Several keyhole craniotomies were fashioned including supraorbital subfrontal, retrosigmoid and supracerebellar infratentorial. In each case, a simple durotomy was performed, and the flap was retracted. The da Vinci surgical system was then used to perform arachnoid dissection towards the deep-seated intracranial cisterns. It was not possible to simultaneously pass the 12-mm endoscope and instruments through the keyhole craniotomy in any of the approaches performed, limiting visualization. The articulated instruments provided greater dexterity than existing tools, but the instrument arms could not be placed in parallel through the keyhole craniotomy and, therefore, could not be advanced to the deep cisterns without significant clashing. The da Vinci console offered considerable ergonomic advantages over the existing operating room arrangement, allowing the operating surgeon to remain non-sterile and seated comfortably throughout the procedure. However, the lack of haptic feedback was a notable limitation. In conclusion, while robotic platforms have the potential to greatly enhance the performance of transcranial approaches, there is strong justification for research into next-generation robots, better suited to keyhole neurosurgery.

Feasibility Study of Core Design with a Monte Carlo Code for APR1400 Initial core

Energy Technology Data Exchange (ETDEWEB)

Kim, Jinsun; Chang, Do Ik; Seong, Kibong [KEPCO NF, Daejeon (Korea, Republic of)

2014-10-15

The Monte Carlo calculation becomes more popular and useful nowadays due to the rapid progress in computing power and parallel calculation techniques. There have been many attempts to analyze a commercial core by Monte Carlo transport code using the enhanced computer capability, recently. In this paper, Monte Carlo calculation of APR1400 initial core has been performed and the results are compared with the calculation results of conventional deterministic code to find out the feasibility of core design using Monte Carlo code. SERPENT, a 3D continuous-energy Monte Carlo reactor physics burnup calculation code is used for this purpose and the KARMA-ASTRA code system, which is used for a deterministic code of comparison. The preliminary investigation for the feasibility of commercial core design with Monte Carlo code was performed in this study. Simplified core geometry modeling was performed for the reactor core surroundings and reactor coolant model is based on two region model. The reactivity difference at HZP ARO condition between Monte Carlo code and the deterministic code is consistent with each other and the reactivity difference during the depletion could be reduced by adopting the realistic moderator temperature. The reactivity difference calculated at HFP, BOC, ARO equilibrium condition was 180 ±9 pcm, with axial moderator temperature of a deterministic code. The computing time will be a significant burden at this time for the application of Monte Carlo code to the commercial core design even with the application of parallel computing because numerous core simulations are required for actual loading pattern search. One of the remedy will be a combination of Monte Carlo code and the deterministic code to generate the physics data. The comparison of physics parameters with sophisticated moderator temperature modeling and depletion will be performed for a further study.

Developing Computer Model-Based Assessment of Chemical Reasoning: A Feasibility Study

Science.gov (United States)

Liu, Xiufeng; Waight, Noemi; Gregorius, Roberto; Smith, Erica; Park, Mihwa

2012-01-01

This paper reports a feasibility study on developing computer model-based assessments of chemical reasoning at the high school level. Computer models are flash and NetLogo environments to make simultaneously available three domains in chemistry: macroscopic, submicroscopic, and symbolic. Students interact with computer models to answer assessment…

Reactions to a remote-controlled video-communication robot in seniors' homes: a pilot study of feasibility and acceptance.

Science.gov (United States)

Seelye, Adriana M; Wild, Katherine V; Larimer, Nicole; Maxwell, Shoshana; Kearns, Peter; Kaye, Jeffrey A

2012-12-01

Remote telepresence provided by tele-operated robotics represents a new means for obtaining important health information, improving older adults' social and daily functioning and providing peace of mind to family members and caregivers who live remotely. In this study we tested the feasibility of use and acceptance of a remotely controlled robot with video-communication capability in independently living, cognitively intact older adults. A mobile remotely controlled robot with video-communication ability was placed in the homes of eight seniors. The attitudes and preferences of these volunteers and those of family or friends who communicated with them remotely via the device were assessed through survey instruments. Overall experiences were consistently positive, with the exception of one user who subsequently progressed to a diagnosis of mild cognitive impairment. Responses from our participants indicated that in general they appreciated the potential of this technology to enhance their physical health and well-being, social connectedness, and ability to live independently at home. Remote users, who were friends or adult children of the participants, were more likely to test the mobility features and had several suggestions for additional useful applications. Results from the present study showed that a small sample of independently living, cognitively intact older adults and their remote collaterals responded positively to a remote controlled robot with video-communication capabilities. Research is needed to further explore the feasibility and acceptance of this type of technology with a variety of patients and their care contacts.

Feasibility Study on Manufacturing Lightweight Aggregates from Water Purification Sludge

Science.gov (United States)

Peng, Ching-Fang; Chen, How-Ji

2018-02-01

This study mainly discussed the feasibility of manufacturing lightweight aggregates from water purification sludge in Taiwan. They were analysed for the physical and chemical composition before the sintering test for lightweight aggregates in a laboratory. Then the physical and mechanical properties of the synthesized aggregates were assessed. The result showed that the chemical composition of sludge in the water purification plants was within the appropriate range for manufacturing lightweight aggregate as proposed in the literature. The sintering test demonstrated that the particle density of aggregates from the ten types of water purification sludge were mostly less than 1.8 g/cm3. In addition, the dry unit weight, the organic impurity, the ignition loss, and other characteristics of synthesized aggregates met the requirement of CNS standards, while its water absorption and crushing strength also fulfilled the general commercial specifications. Therefore, reclamation of water purification sludge for production of lightweight aggregate is indeed feasible.

Concurrent paclitaxel and radiotherapy. Treatment feasibility studies

International Nuclear Information System (INIS)

Vogt, H.G.; Martin, T.; Kolotas, C.; Hey, S.; Schneider, L.; Templin, T.; Zamboglou, N.; Dornoff, W.; Kettner, H.

1997-01-01

with 5x18 Gy/week up to 59.4 to 73.8 Gy. - VII. Concurrent paclitaxel and radiation for gliomas of the brain: 100 mg/m 2 paclitaxel as a 3-hour infusion weekly for 6 weeks simultaneous with radiotherapy in shrinking field technique with 5x2 Gy/week up to 60 Gy. Results: Our initial experiences with weekly application of paclitaxel as a 3-hour infusion in the dosages we used for simultaneous radiochemotherapy of malignancies in different anatomical sites has shown that this treatment concept is feasible, safe and effective. Conclusions: Whether this combined modality will enhance the response rates or influence survival rates has yet to be confirmed in phase-III studies. (orig.) [de

Tribal Utility Feasibility Study

Energy Technology Data Exchange (ETDEWEB)

Engel, R. A.; Zoellick, J. J.

2007-06-30

The Schatz Energy Research Center (SERC) assisted the Yurok Tribe in investigating the feasibility of creating a permanent energy services program for the Tribe. The original purpose of the DOE grant that funded this project was to determine the feasibility of creating a full-blown Yurok Tribal electric utility to buy and sell electric power and own and maintain all electric power infrastructure on the Reservation. The original project consultant found this opportunity to be infeasible for the Tribe. When SERC took over as project consultant, we took a different approach. We explored opportunities for the Tribe to develop its own renewable energy resources for use on the Reservation and/or off-Reservation sales as a means of generating revenue for the Tribe. We also looked at ways the Tribe can provide energy services to its members and how to fund such efforts. We identified opportunities for the development of renewable energy resources and energy services on the Yurok Reservation that fall into five basic categories: • Demand-side management – This refers to efforts to reduce energy use through energy efficiency and conservation measures. • Off-grid, facility and household scale renewable energy systems – These systems can provide electricity to individual homes and Tribal facilities in areas of the Reservation that do not currently have access to the electric utility grid. • Village scale, micro-grid renewable energy systems - These are larger scale systems that can provide electricity to interconnected groups of homes and Tribal facilities in areas of the Reservation that do not have access to the conventional electric grid. This will require the development of miniature electric grids to serve these interconnected facilities. • Medium to large scale renewable energy development for sale to the grid – In areas where viable renewable energy resources exist and there is access to the conventional electric utility grid, these resources can be

Resolution Enhancement of Multilook Imagery

Energy Technology Data Exchange (ETDEWEB)

Galbraith, Amy E. [Univ. of Arizona, Tucson, AZ (United States)

2004-07-01

This dissertation studies the feasibility of enhancing the spatial resolution of multi-look remotely-sensed imagery using an iterative resolution enhancement algorithm known as Projection Onto Convex Sets (POCS). A multi-angle satellite image modeling tool is implemented, and simulated multi-look imagery is formed to test the resolution enhancement algorithm. Experiments are done to determine the optimal con guration and number of multi-angle low-resolution images needed for a quantitative improvement in the spatial resolution of the high-resolution estimate. The important topic of aliasing is examined in the context of the POCS resolution enhancement algorithm performance. In addition, the extension of the method to multispectral sensor images is discussed and an example is shown using multispectral confocal fluorescence imaging microscope data. Finally, the remote sensing issues of atmospheric path radiance and directional reflectance variations are explored to determine their effect on the resolution enhancement performance.

[Active and safe with wheeled walkers : Pilot study on feasibility of mobility exercises for wheeled walker users].

Science.gov (United States)

Pflaum, Marina; Lang, Frieder R; Freiberger, Ellen

2016-07-01

The number of older people with mobility impairments using wheeled walkers is increasing; however, the handling of these walking aids is often ineffective. Moreover, age-associated functional loss, environmental demands and fear of falling may additionally challenge mobility. The new training program "Active and safe with wheeled walkers" aims to enhance skills and to improve mobility. The present pilot study was carried out to assess the feasibility of the training as well as to identify training effects and methodological insights for further research. The study was carried out with 28 wheeled walker users (age 68-91 years) in assisted living facilities using a pre-post design. Of the participants 13 persons were trained for 10 weeks (90 min, twice a week) and 15 persons served as a control group. Data were collected on functional mobility, hand strength, leg strength, balance, walker handling and fear of falling. The drop-out rate for the training was 38 % due to health concerns (n = 2), lack of time (n = 1) and changes in health status independent of training (n = 3). Medium to large effects were detected. Data regarding the recruitment strategy and the acceptance of individual exercises are available. The results indicate a good feasibility and effectiveness of the training. The simple accessibility of the training was conducive for the regular participation. The everyday relevance of the results and the lack of comparable interventions suggest that further research efforts be carried out. Recruitment strategies, training requirements and data collection methods need to be optimized.

Photorealistic avatar and teen physical activity: Feasibility and preliminary efficacy

Science.gov (United States)

Exergames played with a photorealistic avatar may enhance motivation to play, as well as frequency, duration, and intensity of game-play. This manuscript reports the feasibility and preliminary efficacy of an exergame played with a photorealistic avatar on physical activity intensity in a laboratory...

Economic Feasibility Study for Using Irradiation Technology in Preservation of Animalism Foods

International Nuclear Information System (INIS)

El Gameel, E.A.

2011-01-01

The present study discus the economic feasibility for the preservation animalism foods by using irradiation technology. This study has included the technical data, regression foretelling for the throughput, determination of irradiators types and radiation sources activity. This study comprises the financial analysis for the establishment animalism foods irradiation facilities (types: tote box, pallet conveyor) and the national return

Harvest for health gardening intervention feasibility study in cancer survivors.

Science.gov (United States)

Blair, Cindy K; Madan-Swain, Avi; Locher, Julie L; Desmond, Renee A; de Los Santos, Jennifer; Affuso, Olivia; Glover, Tony; Smith, Kerry; Carley, Joseph; Lipsitz, Mindy; Sharma, Ayushe; Krontiras, Helen; Cantor, Alan; Demark-Wahnefried, Wendy

2013-08-01

Cancer survivors are at increased risk for second malignancies, cardiovascular disease, diabetes, and functional decline. Evidence suggests that a healthful diet and physical activity may reduce the risk of chronic disease and improve health in this population. We conducted a feasibility study to evaluate a vegetable gardening intervention that paired 12 adult and child cancer survivors with Master Gardeners to explore effects on fruit and vegetable intake, physical activity, quality-of-life, and physical function. Throughout the year-long study period, the survivor-Master Gardener dyads worked together to plan/plant three gardens, harvest/rotate plantings, and troubleshoot/correct problems. Data on diet, physical activity, and quality-of-life were collected via surveys; anthropometrics and physical function were objectively measured. Acceptability of the intervention was assessed with a structured debriefing survey. The gardening intervention was feasible (robust enrollment; minimal attrition) and well-received by cancer survivors and Master Gardeners. Improvement in three of four objective measures of strength, agility, and endurance was observed in 90% of survivors, with the following change scores [median (interquartile range)] noted between baseline and one-year follow-up: hand grip test [+ 4.8 (3.0, 6.7) kg], 2.44 meter Get-Up-and-Go [+ 1.0 (+ 1.8, + 0.2) seconds], 30-second chair stand [+ 3.0 (+ 1.0, 5.0) stands], and six-minute walk [+ 11.6 (6.1, 48.8) meters]. Increases of ≥ 1 fruit and vegetable serving/day and ≥ 30 minutes/week of physical activity were observed in 40% and 60%, respectively. These preliminary results support the feasibility and acceptability of a mentored gardening intervention and suggest that it may offer a novel and promising strategy to improve fruit and vegetable consumption, physical activity, and physical function in cancer survivors. A larger randomized controlled trial is needed to confirm our results.

Satellite images to aircraft in flight. [GEOS image transmission feasibility analysis

Science.gov (United States)

Camp, D.; Luers, J. K.; Kadlec, P. W.

1977-01-01

A study has been initiated to evaluate the feasibility of transmitting selected GOES images to aircraft in flight. Pertinent observations that could be made from satellite images on board aircraft include jet stream activity, cloud/wind motion, cloud temperatures, tropical storm activity, and location of severe weather. The basic features of the Satellite Aircraft Flight Environment System (SAFES) are described. This system uses East GOES and West GOES satellite images, which are interpreted, enhanced, and then retransmitted to designated aircraft.

Feasibility study of a level gauge using cosmic-rays

International Nuclear Information System (INIS)

Matsuda, Hideharu; Fukaya, Mitsuharu; Minato, Susumu

1989-01-01

Cosmic-ray intensities were measured at the stairs in a subway station in Nagoya City, inside a tall concrete building and under a cylindrical water tank to examine the feasibility of a cosmic-ray level gauge using a scintillation counter. The measured results agreed quite well with theoretical calculations. The maximum distinguishable water depth was evaluated to be approximately the radius of the tank from the results of many systematic calculations. It was found from these results that the practical application of a cosmic-ray level gauge is feasible. (author)

Historic Schools: Renovation vs. Replacement & the Role of a Feasibility Study.

Science.gov (United States)

National Trust for Historic Preservation, Washington, DC.

Weighing the pros and cons of renovating a historic neighborhood school or building a new one takes preservation "know-how," experience, and creativity. The potential for renovation is routinely dismissed without full consideration of the facts and long-term implications. Central to this decision-making process is the feasibility study,…

Battery energy storage market feasibility study - Expanded report

International Nuclear Information System (INIS)

Kraft, S.; Akhil, A.

1997-09-01

Under the sponsorship of the US Department of Energy's Office of Utility Technologies, the Energy Storage Systems Analysis and Development Department at Sandia National Laboratories (SNL) contracted Frost and Sullivan to conduct a market feasibility study of energy storage systems. The study was designed specifically to quantify the battery energy storage market for utility applications. This study was based on the SNL Opportunities Analysis performed earlier. Many of the groups surveyed, which included electricity providers, battery energy storage vendors, regulators, consultants, and technology advocates, viewed battery storage as an important technology to enable increased use of renewable energy and as a means to solve power quality and asset utilization issues. There are two versions of the document available, an expanded version (approximately 200 pages, SAND97-1275/2) and a short version (approximately 25 pages, SAND97-1275/1)

Battery energy storage market feasibility study -- Expanded report

Energy Technology Data Exchange (ETDEWEB)

Kraft, S. [Frost and Sullivan, Mountain View, CA (United States); Akhil, A. [Sandia National Labs., Albuquerque, NM (United States). Energy Storage Systems Analysis and Development Dept.

1997-09-01

Under the sponsorship of the US Department of Energy`s Office of Utility Technologies, the Energy Storage Systems Analysis and Development Department at Sandia National Laboratories (SNL) contracted Frost and Sullivan to conduct a market feasibility study of energy storage systems. The study was designed specifically to quantify the battery energy storage market for utility applications. This study was based on the SNL Opportunities Analysis performed earlier. Many of the groups surveyed, which included electricity providers, battery energy storage vendors, regulators, consultants, and technology advocates, viewed battery storage as an important technology to enable increased use of renewable energy and as a means to solve power quality and asset utilization issues. There are two versions of the document available, an expanded version (approximately 200 pages, SAND97-1275/2) and a short version (approximately 25 pages, SAND97-1275/1).

Preliminary feasibility study on production of cobalt-60 source for industrial irradiation

International Nuclear Information System (INIS)

Joo, Po Kook; Park, Kyung Bae; Ahn, Yun Soo; Lee, Jong Tai; Kim, Hark Rho

1999-05-01

As there is a high possible demand of industrial Co-60 source in the world market, feasibility study of a project was performed to produce and to export Co-60 sources, utilizing KEPCO's Wolsung NPP for irradiation of cobalt and KAERI's hot-cells for fabrication of cobalt sources. Main concerns of the study were to understand irradiation and fabrication (encapsulation) processes and to examine related technologies, required facilities and equipment. In particular, it was examined intensively if it would be possible to modify facilities around the reactor vessel of Wolsung NPP tp substantiate the related licensing in order to irradiate cobalt in the reactor. It is expected that once, if cooperation scheme with MDS Nordion of Canada is established, main issues such as modification of facilities, related licensing, raw material procurement and technology transfer for high quality product will be solved. In order to review overall feasibility of the project, present status and prospect of the world market was surveyed and various usages of cobalt sources were reviewed with emphasis on possible demand increase per usage. Food poisoning accidents are prevailing worldwide and food irradiation with cobalt sources is considered as a promising measure to prevent them and may bring forth high increase of cobalt sources demand in the world market. Preliminary economic feasibility was studied in conservation, evaluating roughly the investment and the operating cost based on materials from various information sources. (author)

Privatization and the allure of franchising: a Zambian feasibility study.

Science.gov (United States)

Fiedler, John L; Wight, Jonathan B

2003-01-01

Efforts to privatize portions of the health sector have proven more difficult to implement than had been anticipated previously. One common bottleneck encountered has been the traditional organizational structure of the private sector, with its plethora of independent, single physician practices. The atomistic nature of the sector has rendered many privatization efforts difficult, slow and costly-in terms of both organizational development and administration. In many parts of Africa, in particular, the shortages of human and social capital, and the fragile nature of legal institutions, undermine the appeal of privatization. The private sector is left with inefficiencies, high prices and costs, and a reduced effective demand. The result is the simultaneous existence of excess capacity and unmet need. One potential method to improve the efficiency of the private sector, and thereby enhance the likelihood of successful privatization, is to transfer managerial technology--via franchising--from models that have proven successful elsewhere. This paper presents a feasibility analysis of franchizing the successful Bolivian PROSALUD system's management package to Zambia. The assessment, based on PROSALUD's financial model, demonstrates that technology transfer requires careful adaptation to local conditions and, in this instance, would still require significant external assistance.

Prevention of anxiety disorders in primary care: A feasibility study

Directory of Open Access Journals (Sweden)

Batelaan Neeltje M

2012-11-01

Full Text Available Abstract Background Anxiety disorders are highly prevalent in primary care and cause a substantial burden of disease. Screening on risk status, followed by preventive interventions in those at risk may prevent the onset of anxiety disorders, and thereby reduce the disease burden. The willingness to participate in screening and interventions is crucial for the scope of preventive strategies, but unknown. This feasibility study, therefore, investigated participation rates of screening and preventive services for anxiety disorders in primary care, and explored reasons to refrain from screening. Methods In three general practices, screening was offered to individuals visiting their general practitioner (total n = 2454. To assess risk status, a 10-item questionnaire was followed by a telephone interview (including the CIDI when scoring above a predefined threshold. Preventive services were offered to those at risk. Participation rates for screening and preventive services for anxiety disorders were assessed. Those not willing to be screened were asked for their main reason to refrain from screening. Results Of all individuals, 17.3% participated in initial screening, and of those with a possible risk status, 56.0% continued screening. In 30.1% of those assessed, a risk status to develop an anxiety disorder was verified. Of these, 22.6% already received some form of mental health treatment and 38.7% of them agreed to participate in a preventive intervention and were referred. The most frequently mentioned reasons to refrain from screening were the emotional burden associated with elevated risk status, the assumption not to be at risk, and a lack of motivation to act upon an elevated risk status by using preventive services. Conclusions Screening in general practice, followed by offering services to prevent anxiety disorders in those at risk did not appear to be a feasible strategy due to low participation rates. To enable the development of

Development of Bioavailability Adjustment Factors: A Feasibility Study

National Research Council Canada - National Science Library

Rembish, Steve

2000-01-01

The primary purpose of this effort is to investigate the feasibility of developing and using bioavailability adjustment factors to modify intake assumptions used in risk assessments on a site-specific basis...

Multnomah County Hydrokinetic Feasibility Study: Final Feasibility Study Report

Energy Technology Data Exchange (ETDEWEB)

Spain, Stephen

2012-03-15

HDR has completed a study of the technical, regulatory, and economic feasibility of installing hydrokinetic turbines under the Morrison, Broadway, and Sellwood bridges. The primary objective of installing hydrokinetic turbines is a demonstration of in-stream hydrokinetic technologies for public education and outreach. Due to the low gradient of the Lower Willamette and the effects of the tide, velocities in the area in consideration are simply not high enough to economically support a commercial installation. While the velocities in the river may at times provide enough energy for a commercial turbine to reach capacity, the frequency and duration of high flow events which provide suitable velocities is not sufficient to support a commercial hydrokinetic installation. We have observed that over an 11 year period, daily average velocities in the Lower Willamette exceeded a nominal cut-in speed of 0.75 m/s only 20% of the time, leaving net zero power production for the remaining 80% of days. The Sellwood Bridge site was estimated to have the best hydrokinetic resource, with an estimated average annual production of about 9,000 kWh. The estimated production could range from 2,500 kWh to 15,000 kWh. Based on these energy estimates, the amount of revenue generated through either a power purchase agreement (PPA) or recovered through net metering is not sufficient to repay the project costs within the life of the turbine. The hydrokinetic resource at the Morrison and Broadway Bridges is slightly smaller than at the Sellwood Bridge. While the Broadway and Morrison Bridges have existing infrastructure that could be utilized, the project is not expected to generate enough revenue to repay the investment. Despite low velocities and energy production, the sites themselves are favorable for installation of a demonstration or experimental project. With high public interest in renewable energy, the possibility exists to develop a hydrokinetic test site which could provide

Feasibility of a large cohort study in sub-Saharan Africa assessed through a four-country study

Directory of Open Access Journals (Sweden)

Shona Dalal

2015-05-01

Full Text Available Background: Large prospective epidemiologic studies are vital in determining disease etiology and forming national health policy. Yet, such studies do not exist in sub-Saharan Africa (SSA notwithstanding the growing burden of chronic diseases. Objective: We explored the feasibility of establishing a large-scale multicountry prospective study at five sites in four sub-Saharan countries. Design: Based on country-specific considerations of feasibility, Nigeria enrolled health care professionals, South Africa and Tanzania enrolled teachers, and Uganda enrolled village residents at one rural and one periurban site each. All sites used a 6-month follow-up period but different approaches for data collection, namely standardized questionnaires filled out by participants or face-to-face interviews. Results: We enrolled 1415 participants from five sites (range 200–489 with a median age of 41 years. Approximately half had access to clean-burning cooking fuel and 70% to piped drinking water, yet 92% had access to a mobile phone. The prevalence of chronic diseases was 49% among 45- to 54-year-olds and was dominated by hypertension (21.7% overall – ranging from 4.5 to 31.2% across sites – and a serious injury in the past 12 months (12.4% overall. About 80% of participants indicated willingness to provide blood samples. At 6-month follow-up, 68% completed a questionnaire (45 to 96% across sites with evidence that mobile phones were particularly useful. Conclusions: Our pilot study indicates that a large-scale prospective study in SSA is feasible, and the burden of chronic disease in SSA may already be substantial necessitating urgent etiologic research and primary prevention.

Can microbes compete with cows for sustainable protein production - A feasibility study on high quality protein.

Science.gov (United States)

Vestergaard, Mike; Chan, Siu Hung Joshua; Jensen, Peter Ruhdal

2016-11-08

An increasing population and their increased demand for high-protein diets will require dramatic changes in the food industry, as limited resources and environmental issues will make animal derived foods and proteins, gradually more unsustainable to produce. To explore alternatives to animal derived proteins, an economic model was built around the genome-scale metabolic network of E. coli to study the feasibility of recombinant protein production as a food source. Using a novel model, we predicted which microbial production strategies are optimal for economic return, by capturing the tradeoff between the market prices of substrates, product output and the efficiency of microbial production. A case study with the food protein, Bovine Alpha Lactalbumin was made to evaluate the upstream economic feasibilities. Simulations with different substrate profiles at maximum productivity were used to explore the feasibility of recombinant Bovine Alpha Lactalbumin production coupled with market prices of utilized materials. We found that recombinant protein production could be a feasible food source and an alternative to traditional sources.

Can microbes compete with cows for sustainable protein production - A feasibility study on high quality protein

Science.gov (United States)

Vestergaard, Mike; Chan, Siu Hung Joshua; Jensen, Peter Ruhdal

2016-11-01

An increasing population and their increased demand for high-protein diets will require dramatic changes in the food industry, as limited resources and environmental issues will make animal derived foods and proteins, gradually more unsustainable to produce. To explore alternatives to animal derived proteins, an economic model was built around the genome-scale metabolic network of E. coli to study the feasibility of recombinant protein production as a food source. Using a novel model, we predicted which microbial production strategies are optimal for economic return, by capturing the tradeoff between the market prices of substrates, product output and the efficiency of microbial production. A case study with the food protein, Bovine Alpha Lactalbumin was made to evaluate the upstream economic feasibilities. Simulations with different substrate profiles at maximum productivity were used to explore the feasibility of recombinant Bovine Alpha Lactalbumin production coupled with market prices of utilized materials. We found that recombinant protein production could be a feasible food source and an alternative to traditional sources.

Homogeneous SLOWPOKE reactor for the production of radio-isotope. A feasibility study

Energy Technology Data Exchange (ETDEWEB)

Busatta, P.; Bonin, H.W. [Royal Military College of Canada, Kingston, Ontario (Canada)]. E-mail: paul.busatta@rmc.ca; bonin-h@rmc.ca

2006-07-01

The purpose of this research is to study the feasibility of replacing the actual heterogeneous fuel core of the present SLOWPOKE-2 by a reservoir containing a homogeneous fuel for the production of Mo-99. The study looked at three items: by using the MCNP Monte Carlo reactor calculation code, develop a series of parameters required for an homogeneous fuel and evaluate the uranyl sulfate concentration of the aqueous solution fuel in order to keep a similar excess reactivity; verify if the homogeneous reactor will retain its inherent safety attributes; and with the new dimensions and geometry of the fuel core, observe whether natural convection can still effectively cool the reactor using the modeling software FEMLAB. It was found that it is indeed feasible to modify the SLOWPOKE-2 reactor for a homogeneous reactor using a solution of uranyl sulfate and water. (author)

Homogeneous SLOWPOKE reactor for the production of radio-isotope. A feasibility study

International Nuclear Information System (INIS)

Busatta, P.; Bonin, H.W.

2006-01-01

The purpose of this research is to study the feasibility of replacing the actual heterogeneous fuel core of the present SLOWPOKE-2 by a reservoir containing a homogeneous fuel for the production of Mo-99. The study looked at three items: by using the MCNP Monte Carlo reactor calculation code, develop a series of parameters required for an homogeneous fuel and evaluate the uranyl sulfate concentration of the aqueous solution fuel in order to keep a similar excess reactivity; verify if the homogeneous reactor will retain its inherent safety attributes; and with the new dimensions and geometry of the fuel core, observe whether natural convection can still effectively cool the reactor using the modeling software FEMLAB. It was found that it is indeed feasible to modify the SLOWPOKE-2 reactor for a homogeneous reactor using a solution of uranyl sulfate and water. (author)

The use of feasibility studies for stepped-wedge cluster randomised trials: protocol for a review of impact and scope.

Science.gov (United States)

Kristunas, Caroline A; Hemming, Karla; Eborall, Helen C; Gray, Laura J

2017-08-01

The stepped-wedge cluster randomised trial (SW-CRT) is a complex design, for which many decisions about key design parameters must be made during the planning. These include the number of steps and the duration of time needed to embed the intervention. Feasibility studies are likely to be useful for informing these decisions and increasing the likelihood of the main trial's success. However, the number of feasibility studies being conducted for SW-CRTs is currently unknown. This review aims to establish the number of feasibility studies being conducted for SW-CRTs and determine which feasibility issues are commonly investigated. Fully published feasibility studies for SW-CRTs will be identified, according to predefined inclusion criteria, from searches conducted in Ovid MEDLINE, Scopus, Embase and PsycINFO. To also identify and gain information on unpublished feasibility studies the following will be contacted: authors of published SW-CRTs (identified from the most recent systematic reviews); contacts for registered SW-CRTs (identified from clinical trials registries); lead statisticians of UK registered clinical trials units and researchers known to work in the area of SW-CRTs.Data extraction will be conducted independently by two reviewers. For the fully published feasibility studies, data will be extracted on the study characteristics, the rationale for the study, the process for determining progression to a main trial, how the study informed the main trial and whether the main trial went ahead. The researchers involved in the unpublished feasibility studies will be contacted to elicit the same information.A narrative synthesis will be conducted and provided alongside a descriptive analysis of the study characteristics. This review does not require ethical approval, as no individual patient data will be used. The results of this review will be published in an open-access peer-reviewed journal. © Article author(s) (or their employer(s) unless otherwise stated in

Implementing the supportive supervision intervention for registered nurses in a long-term care home: a feasibility study.

Science.gov (United States)

McGilton, Katherine S; Profetto-McGrath, Joanne; Robinson, Angela

2013-11-01

This pilot study was conducted in response to the call in 2009 by the International Association of Gerontology and Geriatrics to focus on effective leadership structures in nursing homes and to develop leadership capacity. Few researchers have evaluated interventions aimed at enhancing the leadership ability of registered nurses in long-term care. The aim of the pilot study was to test the feasibility of a three-part supportive supervisory intervention to improve supervisory skills of registered nurses in long-term care. A repeated measures group design was used. Quantitative data were collected from healthcare aides, licensed practical nurses (i.e., supervised staff), and registered nurses (i.e., supervisors). Focus groups with care managers and supervisors examined perceptions of the intervention. There were nonsignificant changes in both the registered nurse supervisors' job satisfaction and the supervised staff's perception of their supervisors' support. Supervised staff scores indicated an increase in the use of research utilization but did not reflect an increase in job satisfaction. Focus group discussions revealed that the supervisors and care managers perceived the workshop to be valuable; however, the weekly self-reflection, coaching, and mentoring components of the intervention were rare and inconsistent. While the primary outcomes were not influenced by the Supportive Supervision Intervention, further effort is required to understand how best to enhance the supportive supervisory skills of RNs. Examples of how to improve the possibility of a successful intervention are advanced. Effective supervisory skills among registered nurses are crucial for improving the quality of care in long-term care homes. Registered nurses are receptive to interventions that will enhance their roles as supervisors. © 2013 Sigma Theta Tau International.

Visually guided male urinary catheterization: a feasibility study.

Science.gov (United States)

Willette, Paul A; Banks, Kevin; Shaffer, Lynn

2013-01-01

Ten percent to 15% of urinary catheterizations involve complications. New techniques to reduce risks and pain are indicated. This study examines the feasibility and safety of male urinary catheterization by nursing personnel using a visually guided device in a clinical setting. The device, a 0.6-mm fiber-optic bundle inside a 14F triple-lumen flexible urinary catheter with a lubricious coating, irrigation port, and angled tip, connects to a camera, allowing real-time viewing of progress on a color monitor. Two emergency nurses were trained to use the device. Male patients 18 years or older presenting to the emergency department with an indication for urinary catheterization using a standard Foley or Coudé catheter were eligible to participate in the study. Exclusion criteria were a current suprapubic tube or gross hematuria prior to the procedure. Twenty-five patients were enrolled. Data collected included success of placement, total procedure time, pre-procedure pain and maximum pain during the procedure, gross hematuria, abnormalities or injuries identified if catheterization failed, occurrence of and reason for equipment failures, and number of passes required for placement. All catheters were successfully placed. The median number of passes required was 1. For all but one patient, procedure time was ≤ 17 minutes. A median increase in pain scores of 1 point from baseline to the maximum was reported. Gross hematuria was observed in 2 patients. The success rate for placement of a Foley catheter with the visually guided device was 100%, indicating its safety, accuracy, and feasibility in a clinical setting. Minimal pain was associated with the procedure. Copyright © 2013 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.

Self-management toolkit and delivery strategy for end-of-life pain: the mixed-methods feasibility study.

Science.gov (United States)

Bennett, Michael I; Mulvey, Matthew R; Campling, Natasha; Latter, Sue; Richardson, Alison; Bekker, Hilary; Blenkinsopp, Alison; Carder, Paul; Closs, Jose; Farrin, Amanda; Flemming, Kate; Gallagher, Jean; Meads, David; Morley, Stephen; O'Dwyer, John; Wright-Hughes, Alexandra; Hartley, Suzanne

2017-12-01

valued. Descriptive analysis of patient-reported outcomes suggested that interference from pain and self-efficacy were likely to be candidates for primary outcomes in a future trial. No adverse events related to the intervention were reported. The health economic analysis suggested that SMART could be cost-effective. We identified key limitations and considerations for a future trial: improve recruitment through widening eligibility criteria, refine the SMST resources content, enhance fidelity of intervention delivery, secure research nurse support at recruiting sites, refine trial procedures (including withdrawal process and data collection frequency), and consider a cluster randomised design with nurse as cluster unit. (1) The recruitment rate was lower than anticipated. (2) The content of the intervention was focused on strong opioids only. (3) The fidelity of intervention delivery was limited by the need for ongoing training and support. (4) Recruitment sites where clinical research nurse support was not secured had lower recruitment rates. (5) The process for recording withdrawal was not sufficiently detailed. (6) The number of follow-up visits was considered burdensome for some participants. (7) The feasibility trial did not have a control arm or assess randomisation processes. A future randomised controlled trial is feasible and acceptable. This study is registered as PROSPERO CRD42014013572; Current Controlled Trials ISRCTN35327119; and National Institute for Health Research (NIHR) Portfolio registration 162114. The NIHR Health Technology Assessment programme.

Report on feasibility study in fiscal 1999. Energy loss reduction project in Myanmar

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

Discussions were given on reduction of greenhouse effect gas emission by improving the efficiency of electric power generation facilities and reducing the power transmission loss in Myanmar to link the project to the clean development mechanism. Shwedaung Power Station, Mann Power Station and the transmission system in Mandalay District were taken up as the object of the discussions. Profitability as a result of improving the thermal power generation facilities was calculated as the financial internal rate of return (FIRR) to discuss the feasibility of the implementation of the project. Since the single-shaft gas turbine currently in use has low efficiency, expansion or new installation of the new compound cycle power generation facilities would be most effective providing excellent thermal efficiency and power generation cost efficiency. The FIRR from improving the Shwedaung thermal power plant was calculated as 12.8%, and the Mann power plant as 9.4%, being regarded sufficiently worth for investment. The measures to reduce the transmission loss include introduction of higher voltage, setting new routes, increasing the conductor sizes, enhancing the power factor, and improving the facilities. The economic internal rate of return (EIRR) and the FIRR were calculated to discuss the project feasibility. In case of assuming the subjected analysis period to be ten years, the EIRR was estimated to be 20.41% (exceeding the social discount rate of 10%) and the FIRR to be 17.56% (exceeding the general loan interest of 15%), indicating the project realizable. (NEDO)

Feasibility and Acceptability of a Web-Based HIV/STD Prevention Program for Adolescent Girls Targeting Sexual Communication Skills

Science.gov (United States)

Widman, L.; Golin, C. E.; Kamke, K.; Massey, J.; Prinstein, M. J.

2017-01-01

Adolescent girls are at substantial risk of sexually transmitted diseases including HIV. To reduce these risks, we developed Health Education And Relationship Training (HEART), a web-based intervention focused on developing sexual assertiveness skills and enhancing sexual decision-making. This study assessed the feasibility and acceptability of…

Raising the profile of pilot and feasibility studies in relation to the development, evaluation and implementation of patient-reported outcome measures.

OpenAIRE

Jones, GL

2017-01-01

This editorial introduces a new special series on the pilot and feasibility testing of patient-reported outcome measures (PROMs) in the on-line open access journal Pilot and Feasibility Studies. Pilot and feasibility studies are typically implemented to address issues of uncertainty before undertaking a larger definitive study such as a randomised controlled trial or large scale survey. This editorial considers the role that such pilot and feasibility testing plays in relation to the developm...

Rebuilding self-confidence after cancer: a feasibility study of life-coaching.

Science.gov (United States)

Wagland, Richard; Fenlon, Deborah; Tarrant, Ruth; Howard-Jones, Gilly; Richardson, Alison

2015-03-01

Cancer survivors often experience decreased self-confidence which impacts negatively on their ability to self-manage the practical, social and emotional problems frequently faced as they emerge from end of treatment. This was a feasibility study of a life-coaching intervention, designed to rebuild confidence of survivors and support transition to life after cancer treatment. A one group pre-test, post-test design was used, recruiting participants from community organisations. Eligibility criteria are as follows: 18, no metastases, and no mental health problems. Participants received one individualised face-to-face and five telephone coaching sessions over 3 months. Outcome measures are as follows: New General Self-Efficacy Scale, Hope Scale, Personal Well-being Index, Assessment of Survivorship Concerns, Quality of Life in Adult Cancer Survivors, Hospital Anxiety and Depression Scale, Social Difficulties Index, and a goal attainment score. Interviews explored feasibility, acceptability and impact of life-coaching and research design. Nine women and two men were recruited, representing varying cancer diagnoses. All outcome measures were sensitive to change and indicated positive trends post-intervention. Participant interviews indicated the intervention was well received and had a positive impact. Lessons were learnt about study design, recruitment and intervention delivery. Life-coaching has a potential to enable cancer survivors to manage the transition to life beyond cancer and effect change on a range of outcomes. The intervention was feasible to deliver and acceptable to survivors at a time when many struggle to make sense of life. It merits further evaluation through a randomised controlled trial.

Istra district heating system. Master plan and feasibility study

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-09-01

This report presents the results of the Feasibility Study of options for improving the efficiency and operating economy of Istra Large-Scale Demonstration Project includes all areas of the town of Istra. However, the Feasibility Study is confined to the five largest adjoining boilers plant areas within the borders of Istra town. The study was conducted from 1999 to 2001 and was based on information collected during this period. The city administration and the district heating company in Istra provided the data. The company RDIEE, Russian Danish Institute for Energy Efficiency, in Istra collected and processed the data under the conduction of Carl Bro a/s in Denmark. The main objectives of the study are to provide the Istra DHC with a number of options for future development of the district heating system based on technical/financial analyses and presenting the best possibilities for improved comfort, operation and business development. More concretely, one or more system improvement scenarios, which can be implemented in the near future as a first step of the recommended medium-term to long-term development, are identified. Another important objective has been to train the specialists of RDIEE in the feasibility study process and to transfer know-how, skills and tools. The model used for this study is adapted to the features and the special problems to be addressed in relation to the Istra district heating system. RDIEE and Istra DHC are thereby provided with a useful tool which may be used for continued study and development after the first phase project has been completed. As usual in the case of input/output models the quality of the results depends very much on the quality of input data. The present report is exclusively based on the consultant's understanding of the provided information. The results and the underlying inputs should be carefully considered before any final decision concerning implementation is taken. Verification of assumptions should also

Internet-based cognitive behavioral therapy for adolescents with anxiety disorders: A feasibility study

Directory of Open Access Journals (Sweden)

Silke Stjerneklar

2018-03-01

Conclusion: Results from this study indicate that a translated and revised version of the Chilled Out program could be a feasible psychological intervention for Danish adolescents with anxiety disorders.

An individualized exercise programme with and without behavioural change enhancement strategies for managing fatigue among frail older people: a quasi-experimental pilot study.

Science.gov (United States)

Liu, Justina Y-W; Lai, Claudia Ky; Siu, Parco M; Kwong, Enid; Tse, Mimi My

2017-04-01

To evaluate the feasibility and preliminary effects of an individualized exercise programme with and without behavioural change enhancement strategies for frail older people with fatigue. A three-arm, single-blinded, quasi-experimental pilot study. Community health centres. A total of 79 frail older people with fatigue, mean age 79.32 years (±7.72). The combined group received a 16-week combined intervention consisting of exercise training and a behavioural change enhancement programme. The exercise group received exercise training and health talks, whereas the control group received only health talks. Feasibility was assessed through the participants' recruitment, retention, attendance and adherence, feedback, and reports of adverse events. The preliminary effects were assessed by the participants' level of fatigue, physical endurance, self-efficacy, and self-perceived compliance with exercise. Feasibility was achievable with high recruitment (87.2%) and low overall attrition (7.1%) rates. A similar reduction in fatigue was identified in all groups, but a trend of greater improvement in physical endurance was observed in the combined group than in the other two groups. The combined group also had a significantly better attendance rate [F(2,76) = 5.64, p behavioural change, when the participants are establishing the habit of exercising daily.

Dementia care mapping to support staff in the care of people with intellectual disability and dementia: a feasibility study.

Science.gov (United States)

Schaap, Feija D; Fokkens, Andrea S; Dijkstra, Geke J; Reijneveld, Sijmen A; Finnema, Evelyn J

2018-04-24

The number of people with intellectual disability and dementia increases; this combination causes behavioural changes. Dementia Care Mapping (DCM) supports staff in dementia care in nursing homes and may be useful in intellectual disability-care. This qualitative study examines the feasibility of DCM for older people with intellectual disability and dementia. The present authors obtained data in focus groups and interviews with professional users and analysed using a framework for feasibility studies. With experts in dementia and intellectual disability researches, the present authors determined the overall feasibility. DCM was found to be feasible in intellectual disability-care, regarding five domains of feasibility. Staff reported DCM to be useful and valuable and addresses to their demand for skills and knowledge. All professional users found DCM feasible in intellectual disability-care, which was confirmed by experts. DCM is feasible in intellectual disability-care. When fully tailored to intellectual disability-care, DCM is useful and provides opportunities to assess its effectiveness. © 2018 The Authors. Journal of Applied Research in Intellectual Disabilities Published by John Wiley & Sons Ltd.

Feasibility study for mega-electron-volt electron beam tomography.

Science.gov (United States)

Hampel, U; Bärtling, Y; Hoppe, D; Kuksanov, N; Fadeev, S; Salimov, R

2012-09-01

Electron beam tomography is a promising imaging modality for the study of fast technical processes. But for many technical objects of interest x rays of several hundreds of keV energy are required to achieve sufficient material penetration. In this article we report on a feasibility study for fast electron beam computed tomography with a 1 MeV electron beam. The experimental setup comprises an electrostatic accelerator with beam optics, transmission target, and a single x-ray detector. We employed an inverse fan-beam tomography approach with radiographic projections being generated from the linearly moving x-ray source. Angular projections were obtained by rotating the object.

Feasibility Study of Non-Destructive Techniques to Measure Corrosion in SAVY Containers

Energy Technology Data Exchange (ETDEWEB)

Davenport, Matthew Nicholas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

2016-07-15

Stainless Steel SAVY containers are used to transport and store nuclear material. They are prone to interior corrosion in the presence of certain chemicals and a low-oxygen environment. SAVY containers also have relatively thin walls to reduce their weight, making their structural integrity more vulnerable to the effects of corrosion. A nondestructive evaluation system that finds and monitors corrosion within containers in use would improve safety conditions and preclude hazards. Non-destructive testing can determine whether oxidation or corrosion is occurring inside the SAVY containers, and there are a variety of non-destructive testing methods that may be viable. The feasibility study described will objectively decide which method best fits the requirements of the facility and the problem. To improve efficiency, the containers cannot be opened during the non-destructive examination. The chosen technique should also be user-friendly and relatively quick to apply. It must also meet facility requirements regarding wireless technology and maintenance. A feasibility study is an objective search for a new technology or product to solve a particular problem. First, the design, technical, and facility feasibility requirements are chosen and ranked in order of importance. Then each technology considered is given a score based upon a standard ranking system. The technology with the highest total score is deemed the best fit for a certain application.

Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, link-to-care, plus treat approach for HIV prevention in the United States.

Science.gov (United States)

Gamble, Theresa; Branson, Bernard; Donnell, Deborah; Hall, H Irene; King, Georgette; Cutler, Blayne; Hader, Shannon; Burns, David; Leider, Jason; Wood, Angela Fulwood; G Volpp, Kevin; Buchacz, Kate; El-Sadr, Wafaa M

2017-08-01

Background/Aims HIV continues to be a major public health threat in the United States, and mathematical modeling has demonstrated that the universal effective use of antiretroviral therapy among all HIV-positive individuals (i.e. the "test and treat" approach) has the potential to control HIV. However, to accomplish this, all the steps that define the HIV care continuum must be achieved at high levels, including HIV testing and diagnosis, linkage to and retention in clinical care, antiretroviral medication initiation, and adherence to achieve and maintain viral suppression. The HPTN 065 (Test, Link-to-Care Plus Treat [TLC-Plus]) study was designed to determine the feasibility of the "test and treat" approach in the United States. Methods HPTN 065 was conducted in two intervention communities, Bronx, NY, and Washington, DC, along with four non-intervention communities, Chicago, IL; Houston, TX; Miami, FL; and Philadelphia, PA. The study consisted of five components: (1) exploring the feasibility of expanded HIV testing via social mobilization and the universal offer of testing in hospital settings, (2) evaluating the effectiveness of financial incentives to increase linkage to care, (3) evaluating the effectiveness of financial incentives to increase viral suppression, (4) evaluating the effectiveness of a computer-delivered intervention to decrease risk behavior in HIV-positive patients in healthcare settings, and (5) administering provider and patient surveys to assess knowledge and attitudes regarding the use of antiretroviral therapy for prevention and the use of financial incentives to improve health outcomes. The study used observational cohorts, cluster and individual randomization, and made novel use of the existing national HIV surveillance data infrastructure. All components were developed with input from a community advisory board, and pragmatic methods were used to implement and assess the outcomes for each study component. Results A total of 76 sites in

Feasibility of peer assessment and clinical audit to self-regulate the quality of physiotherapy services: a mixed methods study.

Science.gov (United States)

Maas, Marjo J M; Nijhuis-van der Sanden, Maria W G; Driehuis, Femke; Heerkens, Yvonne F; van der Vleuten, Cees P M; van der Wees, Philip J

2017-02-10

To evaluate the feasibility of a quality improvement programme aimed to enhance the client-centeredness, effectiveness and transparency of physiotherapy services by addressing three feasibility domains: (1) acceptability of the programme design, (2) appropriateness of the implementation strategy and (3) impact on quality improvement. Mixed methods study. 64 physiotherapists working in primary care, organised in a network of communities of practice in the Netherlands. The programme contained: (1) two cycles of online self-assessment and peer assessment (PA) of clinical performance using client records and video-recordings of client communication followed by face-to-face group discussions, and (2) clinical audit assessing organisational performance. Assessment was based on predefined performance indicators which could be scored on a 5-point Likert scale. Discussions addressed performance standards and scoring differences. All feasibility domains were evaluated qualitatively with two focus groups and 10 in-depth interviews. In addition, we evaluated the impact on quality improvement quantitatively by comparing self-assessment and PA scores in cycles 1 and 2. We identified critical success features relevant to programme development and implementation, such as clarifying expectations at baseline, training in PA skills, prolonged engagement with video-assessment and competent group coaches. Self-reported impact on quality improvement included awareness of clinical and organisational performance, improved evidence-based practice and client-centeredness and increased motivation to self-direct quality improvement. Differences between self-scores and peer scores on performance indicators were not significant. Between cycles 1 and 2, scores for record keeping showed significant improvement, however not for client communication. This study demonstrated that bottom-up initiatives to improve healthcare quality can be effective. The results justify ongoing evaluation to inform

Visualizing feasible operating ranges within tissue engineering systems using a "windows of operation" approach: a perfusion-scaffold bioreactor case study.

Science.gov (United States)

McCoy, Ryan J; O'Brien, Fergal J

2012-12-01

Tissue engineering approaches to developing functional substitutes are often highly complex, multivariate systems where many aspects of the biomaterials, bio-regulatory factors or cell sources may be controlled in an effort to enhance tissue formation. Furthermore, success is based on multiple performance criteria reflecting both the quantity and quality of the tissue produced. Managing the trade-offs between different performance criteria is a challenge. A "windows of operation" tool that graphically represents feasible operating spaces to achieve user-defined levels of performance has previously been described by researchers in the bio-processing industry. This paper demonstrates the value of "windows of operation" to the tissue engineering field using a perfusion-scaffold bioreactor system as a case study. In our laboratory, perfusion bioreactor systems are utilized in the context of bone tissue engineering to enhance the osteogenic differentiation of cell-seeded scaffolds. A key challenge of such perfusion bioreactor systems is to maximize the induction of osteogenesis but minimize cell detachment from the scaffold. Two key operating variables that influence these performance criteria are the mean scaffold pore size and flow-rate. Using cyclooxygenase-2 and osteopontin gene expression levels as surrogate indicators of osteogenesis, we employed the "windows of operation" methodology to rapidly identify feasible operating ranges for the mean scaffold pore size and flow-rate that achieved user-defined levels of performance for cell detachment and differentiation. Incorporation of such tools into the tissue engineer's armory will hopefully yield a greater understanding of the highly complex systems used and help aid decision making in future translation of products from the bench top to the market place. Copyright © 2012 Wiley Periodicals, Inc.

Feasibility of Single Scan for Simultaneous Evaluation of Regional Krypton and Iodine Concentrations with Dual-Energy CT: An Experimental Study.

Science.gov (United States)

Hong, Sae Rom; Chang, Suyon; Im, Dong Jin; Suh, Young Joo; Hong, Yoo Jin; Hur, Jin; Kim, Young Jin; Choi, Byoung Wook; Lee, Hye-Jeong

2016-11-01

Purpose To evaluate the feasibility of a simultaneous single scan of regional krypton and iodine concentrations by using dual-energy computed tomography (CT). Materials and Methods The study was approved by the institutional animal experimental committee. An airway obstruction model was first made in 10 beagle dogs, and a pulmonary arterial occlusion was induced in each animal after 1 week. For each model, three sessions of dual-energy CT (80% krypton ventilation [krypton CT], 80% krypton ventilation with iodine enhancement [mixed-contrast agent CT], and iodine enhancement [iodine CT]) were performed. Krypton maps were made from krypton and mixed-contrast agent CT, and iodine maps were made from iodine and mixed-contrast agent CT. Observers measured overlay Hounsfield units of the diseased and contralateral segments on each map. Values were compared by using the Wilcoxon signed-rank test. Results In krypton maps of airway obstruction, overlay Hounsfield units of diseased segments were significantly decreased compared with those of contralateral segments in both krypton and mixed-contrast agent CT (P = .005 for both). However, the values of mixed-contrast agent CT were significantly higher than those of krypton CT for both segments (P = .005 and .007, respectively). In iodine maps of pulmonary arterial occlusion, values were significantly lower in diseased segments than in contralateral segments for both iodine and mixed-contrast agent CT (P = .005 for both), without significant difference between iodine and mixed-contrast agent CT for both segments (P = .126 and .307, respectively). Conclusion Although some limitations may exist, it might be feasible to analyze regional krypton and iodine concentrations simultaneously by using dual-energy CT. © RSNA, 2016.

Feasibility and effectiveness of the baby friendly community initiative in rural Kenya: study protocol for a randomized controlled trial.

Science.gov (United States)

Kimani-Murage, Elizabeth W; Kimiywe, Judith; Kabue, Mark; Wekesah, Frederick; Matiri, Evelyn; Muhia, Nelson; Wanjohi, Milka; Muriuki, Peterrock; Samburu, Betty; Kanyuira, James N; Young, Sera L; Griffiths, Paula L; Madise, Nyovani J; McGarvey, Stephen T

2015-09-28

Interventions promoting optimal infant and young child nutrition could prevent a fifth of under-5 deaths in countries with high mortality. Poor infant and young child feeding practices are widely documented in Kenya, with potential detrimental effects on child growth, health and survival. Effective strategies to improve these practices are needed. This study aims to pilot implementation of the Baby Friendly Community Initiative (BFCI), a global initiative aimed at promoting optimal infant and young child feeding practices, to determine its feasibility and effectiveness with regards to infant feeding practices, nutrition and health outcomes in a rural setting in Kenya. The study, employing a cluster-randomized trial design, will be conducted in rural Kenya. A total of 12 clusters, constituting community units within the government's Community Health Strategy, will be randomized, with half allocated to the intervention and the other half to the control arm. A total of 812 pregnant women and their respective children will be recruited into the study. The mother-child pairs will be followed up until the child is 6 months old. Recruitment will last approximately 1 year from January 2015, and the study will run for 3 years, from 2014 to 2016. The intervention will involve regular counseling and support of mothers by trained community health workers and health professionals on maternal, infant and young child nutrition. Regular assessment of knowledge, attitudes and practices on maternal, infant and young child nutrition will be done, coupled with assessment of nutritional status of the mother-child pairs and morbidity for the children. Statistical methods will include analysis of covariance, multinomial logistic regression and multilevel modeling. The study is funded by the NIH and USAID through the Program for Enhanced Research (PEER) Health. Findings from the study outlined in this protocol will inform potential feasibility and effectiveness of a community

Developing an undergraduate degree in public transportation administration and management : feasibility study results.

Science.gov (United States)

2006-11-01

Experiences and results of research by the North Carolina Central University Department of Public Administration while a : conducting feasibility study for establishing a new multidisciplinary undergraduate degree in public transportation administrat...

Canton hydroelectric project: feasibility study. Final report, appendices

Energy Technology Data Exchange (ETDEWEB)

1979-05-01

These appendices contain legal, environmental, regulatory, technical and economic information used in evaluating the feasibility of redeveloping the hydroelectric power generating facilities at the Upper and Lower Dams of the Farmington River at Collinsville, CT. (LCL)

Homogeneous Slowpoke reactor for the production of radio-isotope: a feasibility study

Energy Technology Data Exchange (ETDEWEB)

Busetta, P.; Bonin, H.W. [Royal Military College of Canada, Kingston, Ontario (Canada)

2006-09-15

The purpose of this research is to study the feasibility of replacing the actual heterogeneous fuel core of the present SLOWPOKE-2 by a reservoir containing a homogeneous fuel for the production of Mo-99. The study looked at three items: by using the MCNP Monte Carlo reactor calculation code, develop a series of parameters required for an homogeneous fuel and evaluate the uranyl sulfate concentration of the aqueous solution fuel in order to keep a similar excess reactivity; verify if the homogeneous react will retain its inherent safety attributes; and with the new dimensions and geometry of the fuel core, observe whether natural convection can still effectively cool the reactor using the modeling software FEMLAB(r). It was found that it is needed feasible to modify the SLOWPOKE-2 reactor for a homogeneous reactor using a solution of uranyl sulfate and water. (author)

Feasibility and usefulness of using swallow contrast-enhanced ultrasound to diagnose Zenker's diverticulum: preliminary results.

Science.gov (United States)

Cui, Xin-Wu; Ignee, Andre; Baum, Ulrich; Dietrich, Christoph F

2015-04-01

Zenker's diverticulum (ZD) may be misdiagnosed on conventional ultrasound as a thyroid nodule or other lesion. A barium esophagram is usually used to confirm the diagnosis; however, this procedure exposes the patient to radiation. The aim of this study was to evaluate the feasibility of using swallow contrast-enhanced ultrasound (swallow-CEUS) to diagnose ZD. Ten consecutive patients with ZD (7 men and 3 women, aged 67 ± 11 y) were included in the study. In 4 patients, ZD was incidentally found on head and neck ultrasound, and in 6 patients, ZD was suspected because of dysphagia. All lesions could be detected on conventional ultrasound before swallow-CEUS. Ten healthy volunteers (8 men and 2 women, aged 60 ± 12 y) were chosen as a control group. Written informed consent was obtained. With the patient in the sitting or upright position, conventional ultrasound was performed first to image the lesion, then the patient was asked to swallow ultrasound contrast agent (UCA) (2-4 drops of SonoVue diluted with about 200 mL of tap water). Transity of the contrast agent in the esophagus was imaged with CEUS. Retention of the UCA in the diverticulum was monitored for at least 3 min. All patients underwent a barium esophagram as the gold standard. Swallow-CEUS revealed that in all patients (100%), the UCA was transported from the pharynx to the esophagus while the patient swallowed. ZD appeared as a pouch-shaped structure at the posterior pharyngo-esophageal junction that retained UCA longer than 3 min. The barium esophagram confirmed the diagnosis of ZD in all patients. For the 10 volunteers, no abnormal structure (retaining UCA) was detected during or after swallowing of UCA. With the advantages of no radiation and bedside availability, swallow-CEUS may become a method of choice in confirmation of the diagnosis of ZD, especially when ZD is suspected on conventional ultrasound. Copyright © 2015 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier

Feasibility Study of a Performance-Based Teacher Education Curriculum in Language Arts.

Science.gov (United States)

Rudman, Masha Kabakow

This report of a feasibility study, conducted under the provisions of a model elementary teacher education grant from the U.S. Office of Education, is in five parts. Chapter one contains an overview of and rationale for a performance-based teacher education program, a brief history of the study, the attitude and ability goals expected from…

Economical and technical feasibility study of some radioisotopes production for medical application

International Nuclear Information System (INIS)

Souza, A.L.A.B. de.

1985-01-01

The economical and technical feasibility study of the production in reactors of some radioisotopes most used in medicine, are presented. The clinical applications of each radioisotope as well as its radioactive concentrations and specific activities are related. Irradiation procedures based in the foregoing data are given. Part of the study is dedicated to quality control. (M.A.C.) [pt

Feasibility study of Transcutaneous Electrical Nerve Stimulation (TENS) for cancer bone pain.

Science.gov (United States)

Bennett, Michael I; Johnson, Mark I; Brown, Sarah R; Radford, Helen; Brown, Julia M; Searle, Robert D

2010-04-01

This multicenter study assessed the feasibility of conducting a phase III trial of transcutaneous electrical nerve stimulation (TENS) in patients with cancer bone pain recruited from palliative care services. Eligible patients received active and placebo TENS for 1 hour at site of pain in a randomized crossover design; median interval between applications 3 days. Responses assessed at 30 and 60 minutes included numerical and verbal ratings of pain at rest and on movement, and pain relief. Recruitment, tolerability, adverse events, and effectiveness of blinding were also evaluated. Twenty-four patients were randomised and 19 completed both applications. The intervention was well tolerated. Five patients withdrew: 3 due to deteriorating performance status, and 2 due to increased pain (1 each following active and placebo TENS). Confidence interval estimation around the differences in outcomes between active and placebo TENS suggests that TENS has the potential to decrease pain on movement more than pain on rest. Nine patients did not consider that a placebo was used; the remaining 10 correctly identified placebo TENS. Feasibility studies are important in palliative care prior to undertaking clinical trials. Our findings suggest that further work is required on recruitment strategies and refining the control arm before evaluating TENS in cancer bone pain. Cancer bone pain is common and severe, and partly mediated by hyperexcitability. Animal studies suggest that Transcutaneous Electrical Nerve Stimulation can reduce hyperalgesia. This study examined the feasibility of evaluating TENS in patients with cancer bone pain in order to optimize methods before a phase III trial. Copyright 2010 American Pain Society. Published by Elsevier Inc. All rights reserved.

Is an opportunistic primary care-based intervention for non-responders to bowel screening feasible and acceptable? A mixed-methods feasibility study in Scotland.

Science.gov (United States)

Calanzani, Natalia; Cavers, Debbie; Vojt, Gabriele; Orbell, Sheina; Steele, Robert J C; Brownlee, Linda; Smith, Steve; Patnick, Julietta; Weller, David; Campbell, Christine

2017-10-11

We aimed to test whether a brief, opportunistic intervention in general practice was a feasible and acceptable way to engage with bowel screening non-responders. This was a feasibility study testing an intervention which comprised a brief conversation during routine consultation, provision of a patient leaflet and instructions to request a replacement faecal occult blood test kit. A mixed-methods approach to evaluation was adopted. Data were collected from proformas completed after each intervention, from the Bowel Screening Centre database and from questionnaires. Semi-structured interviews were carried out. We used descriptive statistics, content and framework analysis to determine intervention feasibility and acceptability. Bowel screening non-responders (as defined by the Scottish Bowel Screening Centre) and primary care professionals working in five general practices in Lothian, Scotland. Several predefined feasibility parameters were assessed, including numbers of patients engaging in conversation, requesting a replacement kit and returning it, and willingness of primary care professionals to deliver the intervention. The intervention was offered to 258 patients in five general practices: 220 (87.0%) engaged with the intervention, 60 (23.3%) requested a new kit, 22 (8.5%) kits were completed and returned. Interviews and questionnaires suggest that the intervention was feasible, acceptable and consistent with an existing health prevention agenda. Reported challenges referred to work-related pressures, time constraints and practice priorities. This intervention was acceptable and resulted in a modest increase in non-responders participating in bowel screening, although outlined challenges may affect sustained implementation. The strategy is also aligned with the increasing role of primary care in promoting bowel screening. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use

Feasibility Study of Biomass Electrical Generation on Tribal Lands

Energy Technology Data Exchange (ETDEWEB)

Tom Roche; Richard Hartmann; Joohn Luton; Warren Hudelson; Roger Blomguist; Jan Hacker; Colene Frye

2005-03-29

The goals of the St. Croix Tribe are to develop economically viable energy production facilities using readily available renewable biomass fuel sources at an acceptable cost per kilowatt hour ($/kWh), to provide new and meaningful permanent employment, retain and expand existing employment (logging) and provide revenues for both producers and sellers of the finished product. This is a feasibility study including an assessment of available biomass fuel, technology assessment, site selection, economics viability given the foreseeable fuel and generation costs, as well as an assessment of the potential markets for renewable energy.

Feasibility Study of a Lunar Analog Bed Rest Model