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Sample records for engines application detection

  1. New quickest transient detection methodology. Nuclear engineering applications

    International Nuclear Information System (INIS)

    Wang, Xin; Jevremovic, Tatjana; Tsoukalas, Lefteri H.

    2003-01-01

    A new intelligent systems methodology for quickest online transient detection is presented. Based on information that includes, but is not limited to, statistical features, energy of frequency components and wavelet coefficients, the new methodology decides whether a transient has emerged. A fuzzy system makes the final decision, the membership functions of which are obtained by artificial neural networks and adjusted in an online manner. Comparisons are performed with conventional methods for transient detection using simulated and plant data. The proposed methodology could be useful in power plant operations, diagnostic and maintenance activities. It is also considered as a design tool for quick design modifications in a virtual design environment aimed at next generation University Research and Training Reactors (URTRs). (The virtual design environment is pursued as part of the Big-10 Consortium sponsored by the new Innovations in Nuclear Infrastructure and Education (INIE) program sponsored by the US Department of Energy.) (author)

  2. Application of smart transmitter technology in nuclear engineering measurements with level detection algorithm

    International Nuclear Information System (INIS)

    Kang, Hyun Gook; Seong, Poong Hyun

    1994-01-01

    In this study a programmable smart transmitter is designed and applied to the nuclear engineering measurements. In order to apply the smart transmitter technology to nuclear engineering measurements, the water level detection function is developed and applied in this work. In the real time system, the application of level detection algorithm can make the operator of the nuclear power plant sense the water level more rapidly. Furthermore this work can simplify the data communication between the level-sensing thermocouples and the main signal processor because the level signal is determined at field. The water level detection function reduces the detection time to about 8.3 seconds by processing the signal which has the time constant 250 seconds and the heavy noise signal

  3. Enabling tools for high-throughput detection of metabolites: Metabolic engineering and directed evolution applications.

    Science.gov (United States)

    Lin, Jyun-Liang; Wagner, James M; Alper, Hal S

    2017-12-01

    Within the Design-Build-Test Cycle for strain engineering, rapid product detection and selection strategies remain challenging and limit overall throughput. Here we summarize a wide variety of modalities that transduce chemical concentrations into easily measured absorbance, luminescence, and fluorescence signals. Specifically, we cover protein-based biosensors (including transcription factors), nucleic acid-based biosensors, coupled enzyme reactions, bioorthogonal chemistry, and fluorescent and chromogenic dyes and substrates as modalities for detection. We focus on the use of these methods for strain engineering and enzyme discovery and conclude with remarks on the current and future state of biosensor development for application in the metabolic engineering field. Copyright © 2017 Elsevier Inc. All rights reserved.

  4. Rapid Object Detection Systems, Utilising Deep Learning and Unmanned Aerial Systems (uas) for Civil Engineering Applications

    Science.gov (United States)

    Griffiths, D.; Boehm, J.

    2018-05-01

    With deep learning approaches now out-performing traditional image processing techniques for image understanding, this paper accesses the potential of rapid generation of Convolutional Neural Networks (CNNs) for applied engineering purposes. Three CNNs are trained on 275 UAS-derived and freely available online images for object detection of 3m2 segments of railway track. These includes two models based on the Faster RCNN object detection algorithm (Resnet and Incpetion-Resnet) as well as the novel onestage Focal Loss network architecture (Retinanet). Model performance was assessed with respect to three accuracy metrics. The first two consisted of Intersection over Union (IoU) with thresholds 0.5 and 0.1. The last assesses accuracy based on the proportion of track covered by object detection proposals against total track length. In under six hours of training (and two hours of manual labelling) the models detected 91.3 %, 83.1 % and 75.6 % of track in the 500 test images acquired from the UAS survey Retinanet, Resnet and Inception-Resnet respectively. We then discuss the potential for such applications of such systems within the engineering field for a range of scenarios.

  5. Stirling engine application study

    Science.gov (United States)

    Teagan, W. P.; Cunningham, D.

    1983-01-01

    A range of potential applications for Stirling engines in the power range from 0.5 to 5000 hp is surveyed. Over one hundred such engine applications are grouped into a small number of classes (10), with the application in each class having a high degree of commonality in technical performance and cost requirements. A review of conventional engines (usually spark ignition or Diesel) was then undertaken to determine the degree to which commercial engine practice now serves the needs of the application classes and to detemine the nature of the competition faced by a new engine system. In each application class the Stirling engine was compared to the conventional engines, assuming that objectives of ongoing Stirling engine development programs are met. This ranking process indicated that Stirling engines showed potential for use in all application classes except very light duty applications (lawn mowers, etc.). However, this potential is contingent on demonstrating much greater operating life and reliability than has been demonstrated to date by developmental Stirling engine systems. This implies that future program initiatives in developing Stirling engine systems should give more emphasis to life and reliability issues than has been the case in ongoing programs.

  6. Microwave power engineering applications

    CERN Document Server

    Okress, Ernest C

    2013-01-01

    Microwave Power Engineering, Volume 2: Applications introduces the electronics technology of microwave power and its applications. This technology emphasizes microwave electronics for direct power utilization and transmission purposes. This volume presents the accomplishments with respect to components, systems, and applications and their prevailing limitations in the light of knowledge of the microwave power technology. The applications discussed include the microwave heating and other processes of materials, which utilize the magnetron predominantly. Other applications include microwave ioni

  7. Information Engineering and Applications

    CERN Document Server

    Ma, Yan; International Conference on Information Engineering and Applications (IEA) 2011

    2012-01-01

    The International Conference on Information Engineering and Applications (IEA) 2011 will be held on October 21-24, 2011, in Chongqing, China. It is organized by Chongqing Normal University, Chongqing University, Shanghai Jiao Tong University, Nanyang Technological University, the University of Michigan, Chongqing University of Arts and Sciences, and sponsored by the National Natural Science Foundation of China. The objective of IEA 2011 is to facilitate an exchange of information on best practices for the latest research advances in the area of information engineering and intelligence applications, which mainly includes computer science and engineering, informatics, communications and control, electrical engineering, information computing, business intelligence and management. IEA 2011 will provide a forum for engineers and scientists in academia, industry, and government to address the most innovative research and development including technical challenges, social and economic issues, and to present and disc...

  8. Engineering Adaptive Applications

    DEFF Research Database (Denmark)

    Dolog, Peter

    for a domain.In this book, we propose a new domain engineering framework which extends a development process of Web applications with techniques required when designing such adaptive customizable Web applications. The framework is provided with design abstractions which deal separately with information served...

  9. Physics and engineering of radiation detection

    CERN Document Server

    Ahmed, Syed Naeem

    2015-01-01

    Physics and Engineering of Radiation Detection presents an overview of the physics of radiation detection and its applications. It covers the origins and properties of different kinds of ionizing radiation, their detection and measurement, and the procedures used to protect people and the environment from their potentially harmful effects. The second edition is fully revised and provides the latest developments in detector technology and analyses software. Also, more material related to measurements in particle physics and a complete solutions manual have been added.

  10. Rock engineering applications, 1991

    International Nuclear Information System (INIS)

    Franklin, J.A.; Dusseault, M.B.

    1991-01-01

    This book demonstrates how to apply the theories and principles of rock engineering to actual engineering and construction tasks. It features insights on geology for mining and tunnelling applications. It is practical resource that focuses on the latest technological innovation and examines up-to-date procedures used by engineers for coping with complex rock conditions. The authors also discuss question related to underground space, from design approaches to underground housing and storage. And they cover the monitoring of storage caverns for liquid and gaseous products or toxic and radioactive wastes

  11. Engineering Web Applications

    DEFF Research Database (Denmark)

    Casteleyn, Sven; Daniel, Florian; Dolog, Peter

    Nowadays, Web applications are almost omnipresent. The Web has become a platform not only for information delivery, but also for eCommerce systems, social networks, mobile services, and distributed learning environments. Engineering Web applications involves many intrinsic challenges due...... to their distributed nature, content orientation, and the requirement to make them available to a wide spectrum of users who are unknown in advance. The authors discuss these challenges in the context of well-established engineering processes, covering the whole product lifecycle from requirements engineering through...... design and implementation to deployment and maintenance. They stress the importance of models in Web application development, and they compare well-known Web-specific development processes like WebML, WSDM and OOHDM to traditional software development approaches like the waterfall model and the spiral...

  12. Biomedical applications engineering tasks

    Science.gov (United States)

    Laenger, C. J., Sr.

    1976-01-01

    The engineering tasks performed in response to needs articulated by clinicians are described. Initial contacts were made with these clinician-technology requestors by the Southwest Research Institute NASA Biomedical Applications Team. The basic purpose of the program was to effectively transfer aerospace technology into functional hardware to solve real biomedical problems.

  13. Underground engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Nordyke, M D [Lawrence Radiation Laboratory, Livermore, CA (United States)

    1969-07-01

    Developments of any underground engineering application utilizing nuclear explosives involve answering the same questions one encounters in any new area of technology: What are the characteristics of the new tool? How is it applicable to the job to be done? Is it safe to use? and, most importantly, is its use economically acceptable? The many facets of the answers to these questions will be explored. The general types of application presently under consideration will also be reviewed, with particular emphasis on those specific projects actively being worked on by commercial interests and by the U.S. Atomic Energy Commission. (author)

  14. Underground engineering applications

    International Nuclear Information System (INIS)

    Nordyke, M.D.

    1969-01-01

    Developments of any underground engineering application utilizing nuclear explosives involve answering the same questions one encounters in any new area of technology: What are the characteristics of the new tool? How is it applicable to the job to be done? Is it safe to use? and, most importantly, is its use economically acceptable? The many facets of the answers to these questions will be explored. The general types of application presently under consideration will also be reviewed, with particular emphasis on those specific projects actively being worked on by commercial interests and by the U.S. Atomic Energy Commission. (author)

  15. Engineering Adaptive Web Applications

    DEFF Research Database (Denmark)

    Dolog, Peter

    2007-01-01

    suit the user profile the most. This paper summarizes the domain engineering framework for such adaptive web applications. The framework provides guidelines to develop adaptive web applications as members of a family. It suggests how to utilize the design artifacts as knowledge which can be used......Information and services on the web are accessible for everyone. Users of the web differ in their background, culture, political and social environment, interests and so on. Ambient intelligence was envisioned as a concept for systems which are able to adapt to user actions and needs....... With the growing amount of information and services, the web applications become natural candidates to adopt the concepts of ambient intelligence. Such applications can deal with divers user intentions and actions based on the user profile and can suggest the combination of information content and services which...

  16. Physics and engineering of radiation detection

    CERN Document Server

    Ahmed, Syed Naeem

    2007-01-01

    Physics and Engineering of Radiation Detection presents an overview of basic physics of radiation and its applications and covers the origins and properties of different kinds of ionizing radiation, their detection and measurement, and the procedures used to protect people and the environment from their potentially harmful effects. Covering both the basic physics of radiation and its applications, it will provide an up-to-date and coherent account of the origins and properties of the different kinds of ionizing radiation, and their detection and measurement. This book will illustrate the basic physical principles with an abundance of practical, worked-out examples, numerical problems, real world applications, and data, including biological effects, radon, risk assessment, and statistics.

  17. Kerosene detection using laser induced fluorescence imaging for aeronautical engines application; Detection du kerozene par imagerie de fluorescence induite par laser, pour application sur foyer aeronautique

    Energy Technology Data Exchange (ETDEWEB)

    Baranger, Ph.

    2004-10-15

    The new concepts of aeronautical engines, developed to follow the evolution of the European standards of pollution, are generally based on an improvement of the processes of liquid fuel injection and mixture in the combustion chamber. There is currently no model mature enough to work without experimental validation. The purpose of this thesis is to assess the possibility of measuring the kerosene (Jet A1) vapour distribution by PLIF (Planar Laser Induced Fluorescence). That measurement technique must quantitatively image the instantaneous concentrations fields of the vaporized fuel in a spray. The implementation of such a technique needs an experimental spectroscopic study, which was realized on the vapour of fuel. First of all, this study allowed us to determine the properties of the kerosene fluorescence spectrum versus physical parameters such as temperature, pressure or gas mixture composition, especially in presence of oxygen molecules. Then, it was shown that the fluorescence spectrum of the fuel could be reproduce in all physical conditions by a single mixture of four aromatics. Their photophysical properties were also analyzed. Following this spectroscopic study, a phenomenological model for the fluorescence of the gaseous fuel was set up. This model led us to a protocol for an optical diagnostic on this fuel vapour. An experiment was set up to test the implementation and the limits of this technique in simple laboratory conditions. This experiment confirmed that this is indeed a promising technique for the diagnostic of the fuel vapour in aeronautical engine. (author)

  18. Engine Modelling for Control Applications

    DEFF Research Database (Denmark)

    Hendricks, Elbert

    1997-01-01

    In earlier work published by the author and co-authors, a dynamic engine model called a Mean Value Engine Model (MVEM) was developed. This model is physically based and is intended mainly for control applications. In its newer form, it is easy to fit to many different engines and requires little...... engine data for this purpose. It is especially well suited to embedded model applications in engine controllers, such as nonlinear observer based air/fuel ratio and advanced idle speed control. After a brief review of this model, it will be compared with other similar models which can be found...

  19. Industrial applications of affective engineering

    CERN Document Server

    Shiizuka, Hisao; Lee, Kun-Pyo; Otani, Tsuyoshi; Lim, Chee-Peng

    2014-01-01

    This book examines the industrial applications of affective engineering. The contributors cover new analytical methods such as fluctuation, fuzzy logic, fractals, and complex systems. These chapters also include interdisciplinary research that traverses a wide range of fields, including information engineering, human engineering, cognitive science, psychology, and design studies. The text is split into two parts: theory and applications. This work is a collection of the best papers from ISAE2013 (International Symposium of Affective Engineering) held at Kitakyushu, Japan and Japan Kansei Engineering Meeting on March 6-8, 2013.

  20. Applications of a morphological scene change detection (MSCD) for visual leak and failure identification in process and chemical engineering

    Science.gov (United States)

    Tickle, Andrew J.; Harvey, Paul K.; Smith, Jeremy S.

    2010-10-01

    Morphological Scene Change Detection (MSCD) is a process typically tasked at detecting relevant changes in a guarded environment for security applications. This can be implemented on a Field Programmable Gate Array (FPGA) by a combination of binary differences based around exclusive-OR (XOR) gates, mathematical morphology and a crucial threshold setting. The additional ability to set up the system in virtually any location due to the FPGA makes it ideal for insertion into an autonomous mobile robot for patrol duties. However, security is not the only potential of this robust algorithm. This paper details how such a system can be used for the detection of leaks in piping for use in the process and chemical industries and could be deployed as stated in the above manner. The test substance in this work was water, which was pumped either as a liquid or as low pressure steam through a simple pipe configuration with holes at set points to simulate the leaks. These holes were situated randomly at either the center of a pipe (in order to simulate an impact to it) or at a joint or corner (to simulate a failed weld). Imagery of the resultant leaks, which were visualised as drips or the accumulation of steam, which where analysed using MATLAB to determine their pixel volume in order to calibrate the trigger for the MSCD. The triggering mechanism is adaptive to make it possible in theory for the type of leak to be determined by the number of pixels in the threshold of the image and a numerical output signal to state which of the leak situations is being observed. The system was designed using the DSP Builder package from Altera so that its graphical nature is easily comprehensible to the non-embedded system designer. Furthermore, all the data from the DSP Builder simulation underwent verification against MATLAB comparisons using the image processing toolbox in order to validate the results.

  1. Surface electromyography physiology, engineering and applications

    CERN Document Server

    Farina, Dario

    2016-01-01

    The book presents a quantitative approach to the study and use of noninvasively detected electromyographic (EMG) signals, as well as their numerous applications in various aspects of the life sciences. Surface Electromyography: Physiology, Engineering, and Applications is an update of Electromyography: Physiology, Engineering, and Noninvasive Applications (Wiley-IEEE Press, 2004) and focuses on the developments that have taken place over the last decade. The first nine chapters deal with the generation, detection, understanding, interpretation, and modeling of EMG signals. Detection technology, with particular focus on EMG imaging techniques that are based on two-dimensional electrode arrays are also included in the first half of the book. The latter 11 chapters deal with applications, which range fro monitoring muscle fatigue, electrically elicited contractions, posture analysis, prevention of work-related and child-delivery-related neuromuscular disorders, ergonomics, movement analysis, physical therapy, ex...

  2. Engineering applications of soft computing

    CERN Document Server

    Díaz-Cortés, Margarita-Arimatea; Rojas, Raúl

    2017-01-01

    This book bridges the gap between Soft Computing techniques and their applications to complex engineering problems. In each chapter we endeavor to explain the basic ideas behind the proposed applications in an accessible format for readers who may not possess a background in some of the fields. Therefore, engineers or practitioners who are not familiar with Soft Computing methods will appreciate that the techniques discussed go beyond simple theoretical tools, since they have been adapted to solve significant problems that commonly arise in such areas. At the same time, the book will show members of the Soft Computing community how engineering problems are now being solved and handled with the help of intelligent approaches. Highlighting new applications and implementations of Soft Computing approaches in various engineering contexts, the book is divided into 12 chapters. Further, it has been structured so that each chapter can be read independently of the others.

  3. Nonlinear Approaches in Engineering Applications

    CERN Document Server

    Jazar, Reza

    2012-01-01

    Nonlinear Approaches in Engineering Applications focuses on nonlinear phenomena that are common in the engineering field. The nonlinear approaches described in this book provide a sound theoretical base and practical tools to design and analyze engineering systems with high efficiency and accuracy and with less energy and downtime. Presented here are nonlinear approaches in areas such as dynamic systems, optimal control and approaches in nonlinear dynamics and acoustics. Coverage encompasses a wide range of applications and fields including mathematical modeling and nonlinear behavior as applied to microresonators, nanotechnologies, nonlinear behavior in soil erosion,nonlinear population dynamics, and optimization in reducing vibration and noise as well as vibration in triple-walled carbon nanotubes. This book also: Provides a complete introduction to nonlinear behavior of systems and the advantages of nonlinearity as a tool for solving engineering problems Includes applications and examples drawn from the el...

  4. Engineered Nanoparticles and Their Applications

    International Nuclear Information System (INIS)

    Matsoukas, T.; Desai, T.; Lee, K.

    2015-01-01

    Nanoparticles engineered for shape, size, and surface properties impart special functionalities including catalytic behavior, improved strength, enhanced thermal and electrical conductivity, and controlled release of host molecules. These advances have opened up applications in biomedicine, nano energetic materials, and functional nano composites. This special issue highlights successes in developing nanoparticles for a number of diverse applications.

  5. ELECTRICAL TECHNIQUES FOR ENGINEERING APPLICATIONS.

    Science.gov (United States)

    Bisdorf, Robert J.

    1985-01-01

    Surface electrical geophysical methods have been used in such engineering applications as locating and delineating shallow gravel deposits, depth to bedrock, faults, clay zones, and other geological phenomena. Other engineering applications include determining water quality, tracing ground water contaminant plumes and locating dam seepages. Various methods and electrode arrays are employed to solve particular geological problems. The sensitivity of a particular method or electrode array depends upon the physics on which the method is based, the array geometry, the electrical contrast between the target and host materials, and the depth to the target. Each of the available electrical methods has its own particular advantages and applications which the paper discusses.

  6. Cognitive engineering in aerospace applications

    Science.gov (United States)

    Woods, David D.

    1993-01-01

    The progress that was made with respect to the objectives and goals of the research that is being carried out in the Cognitive Systems Engineering Laboratory (CSEL) under a Cooperative Agreement with NASA Ames Research Center is described. The major objective of this project is to expand the research base in Cognitive Engineering to be able to support the development and human-centered design of automated systems for aerospace applications. This research project is in support of the Aviation Safety/Automation Research plan and related NASA research goals in space applications.

  7. Biomedical applications of control engineering

    CERN Document Server

    Hacısalihzade, Selim S

    2013-01-01

    Biomedical Applications of Control Engineering is a lucidly written textbook for graduate control engin­eering and biomedical engineering students as well as for medical prac­ti­tioners who want to get acquainted with quantitative methods. It is based on decades of experience both in control engineering and clinical practice.   The book begins by reviewing basic concepts of system theory and the modeling process. It then goes on to discuss control engineering application areas like ·         Different models for the human operator, ·         Dosage and timing optimization in oral drug administration, ·         Measuring symptoms of and optimal dopaminergic therapy in Parkinson’s disease, ·         Measure­ment and control of blood glucose le­vels both naturally and by means of external controllers in diabetes, and ·         Control of depth of anaesthesia using inhalational anaesthetic agents like sevoflurane using both fuzzy and state feedback controllers....

  8. Ceramics for Turbine Engine Applications.

    Science.gov (United States)

    1980-03-01

    permet de travailler en compression. 2 - LES TURBINES CONTRAROTATIVES Connues depuis plus de 50 ans dsns lea turbines A vapeur (A grilles radiales) lea...AD-AO87 594 ADVISORY GROUP FOR AEROSPACE RESEARCH AND DEVELOPMENT--ETC F/6 11/2 CERAMICS FOR TURBINE ENGINE APPICATIONS.(U) MAR 8G H M GURTE, J...for Turbine Engine Applications ( X.,, ~LAJ DISTRIBUTION AND AVAILABILITY Ths ai’-t~ ~ru O ACK COVER forp"~ ~So’ 8 6 0 40 NORTH ATLANTIC TREATY

  9. Industrial and Systems Engineering Applications in NASA

    Science.gov (United States)

    Shivers, Charles H.

    2006-01-01

    A viewgraph presentation on the many applications of Industrial and Systems Engineering used for safe NASA missions is shown. The topics include: 1) NASA Information; 2) Industrial Engineering; 3) Systems Engineering; and 4) Major NASA Programs.

  10. Diesel Engine Light Truck Application

    Energy Technology Data Exchange (ETDEWEB)

    None

    2007-12-31

    The Diesel Engine Light Truck Application (DELTA) program consists of two major contracts with the Department of Energy (DOE). The first one under DE-FC05-97-OR22606, starting from 1997, was completed in 2001, and consequently, a final report was submitted to DOE in 2003. The second part of the contract was under DE-FC05-02OR22909, covering the program progress from 2002 to 2007. This report is the final report of the second part of the program under contract DE-FC05-02OR22909. During the course of this contract, the program work scope and objectives were significantly changed. From 2002 to 2004, the DELTA program continued working on light-duty engine development with the 4.0L V6 DELTA engine, following the accomplishments made from the first part of the program under DE-FC05-97-OR22606. The program work scope in 2005-2007 was changed to the Diesel Particulate Filter (DPF) soot layer characterization and substrate material assessment. This final report will cover two major technical tasks. (1) Continuation of the DELTA engine development to demonstrate production-viable diesel engine technologies and to demonstrate emissions compliance with significant fuel economy advantages, covering progress made from 2002 to 2004. (2) DPF soot layer characterization and substrate material assessment from 2005-2007.

  11. Gentic engineering for practical application.

    Science.gov (United States)

    Klingmüller, W

    1979-04-01

    Genetic engineering has ushered in a new era in biology. Although many problems are still to be solved, there are examples that point to a possible later application for the benefit of mankind: Bacteria can be manipulated to degrade crude-oil spillages, to produce human insulin and to bind nitrogen from the air. If all the bacteria that are indigenous to agricultural soils could be made to bind nitrogen, an increase in soil fertility might well result.

  12. Gentic engineering for practical application

    Energy Technology Data Exchange (ETDEWEB)

    Klingmuller, W.

    1979-04-01

    Genetic engineering has ushered in a new era in biology. Although many problems are still to be solved, there are examples that point to a possible later application for the benefit of mankind: Bacteria can be manipulated to degrade crude-oil spillages, to produce human insulin and to bind nitrogen from the air. If all the bacteria that are indigenous to agricultural soils could be made to bind nitrogen, and increase in soil fertility might well result.

  13. Handbook of bioplastics and biocomposites engineering applications

    National Research Council Canada - National Science Library

    Pilla, Srikanth

    2011-01-01

    "The Handbook of Bioplastics & Biocomposites Engineering Applications brings together scientists, from academia and industries, to report on current research and applications, in the bioplastics and biocomposites arena...

  14. Inequalities with applications to engineering

    CERN Document Server

    Cloud, Michael J; Lebedev, Leonid P

    2014-01-01

    This book offers a concise introduction to mathematical inequalities for graduate students and researchers in the fields of engineering and applied mathematics. It begins by reviewing essential facts from algebra and calculus and proceeds with a presentation of the central inequalities of applied analysis, illustrating a wide variety of practical applications. The text provides a gentle introduction to abstract spaces, such as metric, normed, and inner product spaces. It also provides full coverage of the central inequalities of applied analysis, such as Young's inequality, the inequality of the means, Hölder's inequality, Minkowski's inequality, the Cauchy–Schwarz inequality, Chebyshev's inequality, Jensen's inequality, and the triangle inequality. The second edition features extended coverage of applications, including continuum mechanics and interval analysis. It also includes many additional examples and exercises with hints and full solutions that may appeal to upper-level undergraduate and graduate...

  15. Application of engineering surveying in engineering industry

    Directory of Open Access Journals (Sweden)

    Lucia Forgáčová

    2005-11-01

    Full Text Available This is a presentation of the application of surveying principles used in a process of building the electrolytic tinning line at the U.S.Steel s.r.o. Kosice. The work involved is setting up a new network of measuring points, as well as the effective implementation of suitable methodologies, instruments and measuring tools. All of these were focal points for the survey, required during the installation of machinery units for the new tinning line. The coil producing technology utilised on the line entails a high speed movement. In this context all methods and final measurements were adapted to a very high standard of precision in order to ensure a safe working environment and exclude the risk of malfunctions in the final production stage. The smallest variations in the positioning of machinery units, compared with technical drawings, could rise a danger of coil breakdown, line malfunction or personal injury.

  16. Geothermal engineering fundamentals and applications

    CERN Document Server

    Watson, Arnold

    2013-01-01

    This book explains the engineering required to bring geothermal resources into use. The book covers specifically engineering aspects that are unique to geothermal engineering, such as measurements in wells and their interpretation, transport of near-boiling water through long pipelines, turbines driven by fluids other than steam, and project economics. The explanations are reinforced by drawing comparisons with other energy industries.

  17. Nonlinear approaches in engineering applications 2

    CERN Document Server

    Jazar, Reza N

    2013-01-01

    Provides updated principles and applications of the nonlinear approaches in solving engineering and physics problems Demonstrates how nonlinear approaches may open avenues to better, safer, cheaper systems with less energy consumption Has a strong emphasis on the application, physical meaning, and methodologies of nonlinear approaches in different engineering and science problems

  18. Specification framework for engineering adaptive web applications

    NARCIS (Netherlands)

    Frasincar, F.; Houben, G.J.P.M.; Vdovják, R.

    2002-01-01

    The growing demand for data-driven Web applications has led to the need for a structured and controlled approach to the engineering of such applications. Both designers and developers need a framework that in all stages of the engineering process allows them to specify the relevant aspects of the

  19. Nastran's Application in Agricultural Engineering

    Science.gov (United States)

    Vanwicklen, G. L.

    1985-01-01

    Finite element analysis has been recognized as a valuable solution method by agricultural engineers. NASTRAN has been obtained by the Agricultural Engineering Department at the University of Georgia. The NASTRAN Thermal Analyzer has been used in the teaching program for an undergraduate course in heat transfer and will be used for a new graduate course in finite element analysis. The NASTRAN Thermal Analyzer has also been applied to several research problems in the Agricultural Engineering Department.

  20. Soil variability in engineering applications

    Science.gov (United States)

    Vessia, Giovanna

    2014-05-01

    Natural geomaterials, as soils and rocks, show spatial variability and heterogeneity of physical and mechanical properties. They can be measured by in field and laboratory testing. The heterogeneity concerns different values of litho-technical parameters pertaining similar lithological units placed close to each other. On the contrary, the variability is inherent to the formation and evolution processes experienced by each geological units (homogeneous geomaterials on average) and captured as a spatial structure of fluctuation of physical property values about their mean trend, e.g. the unit weight, the hydraulic permeability, the friction angle, the cohesion, among others. The preceding spatial variations shall be managed by engineering models to accomplish reliable designing of structures and infrastructures. Materon (1962) introduced the Geostatistics as the most comprehensive tool to manage spatial correlation of parameter measures used in a wide range of earth science applications. In the field of the engineering geology, Vanmarcke (1977) developed the first pioneering attempts to describe and manage the inherent variability in geomaterials although Terzaghi (1943) already highlighted that spatial fluctuations of physical and mechanical parameters used in geotechnical designing cannot be neglected. A few years later, Mandelbrot (1983) and Turcotte (1986) interpreted the internal arrangement of geomaterial according to Fractal Theory. In the same years, Vanmarcke (1983) proposed the Random Field Theory providing mathematical tools to deal with inherent variability of each geological units or stratigraphic succession that can be resembled as one material. In this approach, measurement fluctuations of physical parameters are interpreted through the spatial variability structure consisting in the correlation function and the scale of fluctuation. Fenton and Griffiths (1992) combined random field simulation with the finite element method to produce the Random

  1. Biocatalysts: application and engineering for industrial purposes.

    Science.gov (United States)

    Jemli, Sonia; Ayadi-Zouari, Dorra; Hlima, Hajer Ben; Bejar, Samir

    2016-01-01

    Enzymes are widely applied in various industrial applications and processes, including the food and beverage, animal feed, textile, detergent and medical industries. Enzymes screened from natural origins are often engineered before entering the market place because their native forms do not meet the requirements for industrial application. Protein engineering is concerned with the design and construction of novel enzymes with tailored functional properties, including stability, catalytic activity, reaction product inhibition and substrate specificity. Two broad approaches have been used for enzyme engineering, namely, rational design and directed evolution. The powerful and revolutionary techniques so far developed for protein engineering provide excellent opportunities for the design of industrial enzymes with specific properties and production of high-value products at lower production costs. The present review seeks to highlight the major fields of enzyme application and to provide an updated overview on previous protein engineering studies wherein natural enzymes were modified to meet the operational conditions required for industrial application.

  2. Engineering Metal Nanostructure for SERS Application

    Directory of Open Access Journals (Sweden)

    Yanqin Cao

    2013-01-01

    Full Text Available Surface-enhanced Raman scattering (SERS has attracted great attention due to its remarkable enhancement and excellent selectivity in the detection of various molecules. Noble metal nanomaterials have usually been employed for producing substrates that can be used in SERS because of their unique local plasma resonance. As the SERS enhancement of signals depends on parameters such as size, shape, morphology, arrangement, and dielectric environment of the nanostructure, there have been a number of studies on tunable nanofabrication and synthesis of noble metals. In this work, we will illustrate progress in engineering metallic nanostructures with various morphologies using versatile methods. We also discuss their SERS applications in different fields and the challenges.

  3. Biomaterials for tissue engineering applications.

    Science.gov (United States)

    Keane, Timothy J; Badylak, Stephen F

    2014-06-01

    With advancements in biological and engineering sciences, the definition of an ideal biomaterial has evolved over the past 50 years from a substance that is inert to one that has select bioinductive properties and integrates well with adjacent host tissue. Biomaterials are a fundamental component of tissue engineering, which aims to replace diseased, damaged, or missing tissue with reconstructed functional tissue. Most biomaterials are less than satisfactory for pediatric patients because the scaffold must adapt to the growth and development of the surrounding tissues and organs over time. The pediatric community, therefore, provides a distinct challenge for the tissue engineering community. Copyright © 2014. Published by Elsevier Inc.

  4. Solid fuel applications to transportation engines

    Energy Technology Data Exchange (ETDEWEB)

    Rentz, Richard L.; Renner, Roy A.

    1980-06-01

    The utilization of solid fuels as alternatives to liquid fuels for future transportation engines is reviewed. Alternative liquid fuels will not be addressed nor will petroleum/solid fuel blends except for the case of diesel engines. With respect to diesel engines, coal/oil mixtures will be addressed because of the high interest in this specific application as a result of the large number of diesel engines currently in transportation use. Final assessments refer to solid fuels only for diesel engines. The technical assessments of solid fuels utilization for transportation engines is summarized: solid fuel combustion in transportation engines is in a non-developed state; highway transportation is not amenable to solid fuels utilization due to severe environmental, packaging, control, and disposal problems; diesel and open-cycle gas turbines do not appear worthy of further development, although coal/oil mixtures for slow speed diesels may offer some promise as a transition technology; closed-cycle gas turbines show some promise for solid fuels utilization for limited applications as does the Stirling engine for use of cleaner solid fuels; Rankine cycle engines show good potential for limited applications, such as for locomotives and ships; and any development program will require large resources and sophisticated equipment in order to advance the state-of-the-art.

  5. Basic Mechanics with Engineering Applications

    CERN Document Server

    Jones, J; Fawcett, J N

    2012-01-01

    This book gives a sufficient grounding in mechanics for engineers to tackle a significant range of problems encountered in the design and specification of simple structures and machines. It also provides an excellent background for students wishing to progress to more advanced studies in three-dimensional mechanics.

  6. Engineering proteins for environmental applications

    NARCIS (Netherlands)

    Janssen, Dick B.; Schanstra, Joost P.

    1994-01-01

    Recently, significant new insight has been obtained into the structure and catalytic mechanism of enzymes that convert environmental pollutants. Recent advances in protein engineering make it possible to use this information for improving the catalytic performance of such enzymes to achieve

  7. Fuzzy logic applications in engineering science

    CERN Document Server

    Harris, J

    2006-01-01

    Fuzzy logic is a relatively new concept in science applications. Hitherto, fuzzy logic has been a conceptual process applied in the field of risk management. Its potential applicability is much wider than that, however, and its particular suitability for expanding our understanding of processes and information in science and engineering in our post-modern world is only just beginning to be appreciated. Written as a companion text to the author's earlier volume "An Introduction to Fuzzy Logic Applications", the book is aimed at professional engineers and students and those with an interest in exploring the potential of fuzzy logic as an information processing kit with a wide variety of practical applications in the field of engineering science and develops themes and topics introduced in the author's earlier text.

  8. Silicone cushions for engineering applications

    International Nuclear Information System (INIS)

    Anon.

    1984-01-01

    When a complex system composed of materials of very different properties is subjected to varying temperature, differential thermal expansion and contraction will produce intolerable stresses unless the parts are separated by suitable cushions. In addition to accommodating differential thermal expansion and contraction, these cushions must absorb shock and vibration, take up dimensional tolerances in the parts, and distribute and attenuate applied loads. We are studying cellular silicone cushions, starting with raw materials and polymer manufacture, to analysis of mechanical and chemical properties, through short- and long-term life testing, in order to tailor cushions to various specific engineering requirements

  9. Compound cycle engine for helicopter application

    Science.gov (United States)

    Castor, Jere G.

    1986-01-01

    The Compound Cycle Engine (CCE) is a highly turbocharged, power compounded, ultra-high power density, light-weight diesel engine. The turbomachinery is similar to a moderate pressure ratio, free power turbine engine and the diesel core is high speed and a low compression ratio. This engine is considered a potential candidate for future military light helicopter applications. This executive summary presents cycle thermodynamic (SFC) and engine weight analyses performed to establish general engine operating parameters and configuration. An extensive performance and weight analysis based on a typical two hour helicopter (+30 minute reserve) mission determined final conceptual engine design. With this mission, CCE performance was compared to that of a T-800 class gas turbine engine. The CCE had a 31% lower-fuel consumption and resulted in a 16% reduction in engine plus fuel and fuel tank weight. Design SFC of the CCE is 0.33 lb-HP-HR and installed wet weight is 0.43 lbs/HP. The major technology development areas required for the CCE are identified and briefly discussed.

  10. Observer design for non linear systems: application to automatic fault detection in process engineering; Synthese d'observateurs pour les systemes non lineaires. Application a la detection automatique de pannes en genie des procedes

    Energy Technology Data Exchange (ETDEWEB)

    Armanet, F.

    1999-04-01

    This thesis describes some theoretical contributions in state observer design for non linear systems and the conception of an automatic fault detector system for a petrochemical process. The first chapter is an overview of the observer theory for non linear systems. The second chapter presents a new methodology of high gain observer design for single-output U-uniformly observable systems. It consists in calculate a symmetric positive definite matrix which allows the design of an high gain observer which is exponentially converging. This observer is applied to estimate the concentrations in a perfectly mixed tank reactor with a kinetic scheme corresponding to the conversion of a product A onto a product B which is also converting onto a product C. In the third chapter, the use of high gain observer is extended for systems which are not uniformly observable but all admissible inputs are locally regularly persistent. A characterization of some of this class of inputs is given and an application for the preceding reactor illustrates this theory. The fourth chapter includes a summary of the observer used in residual generator design for linear and non linear systems. Two examples of automatic fault detector using these methods are describes. In annexed documents, a detailed study of the process modeling and the main observability properties are presented. (author)

  11. Aloe Vera for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Shekh Rahman

    2017-02-01

    Full Text Available Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers.

  12. Aloe Vera for Tissue Engineering Applications.

    Science.gov (United States)

    Rahman, Shekh; Carter, Princeton; Bhattarai, Narayan

    2017-02-14

    Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers.

  13. Collisions engineering. Theory and applications

    Energy Technology Data Exchange (ETDEWEB)

    Fremond, Michel [Rome ' ' Tor Vergata' ' Univ. (Italy). Dept. of Civil Engineering and Computer Science

    2017-02-01

    This book investigates collisions occurring in the motion of solids, in the motion of fluids but also in the motion of pedestrians in crowds. The duration of these presented collisions is short compared to the whole duration of the motion: they are assumed instantaneous. The innovative concept demonstrated in this book is that a system made of two solids, is deformable because their relative position changes. The definition of the velocities of deformation of the system introduced in the classical developments of mechanics, the principle of the virtual work and the laws of thermodynamics, allows a large range of applications such as crowd motions, debris flow motions, and shape memory alloys motions. The set of the applications is even larger: social sciences and mechanics are unified to predict the motion of crowds with application to transport management and to evacuation of theaters management.

  14. Collisions engineering. Theory and applications

    International Nuclear Information System (INIS)

    Fremond, Michel

    2017-01-01

    This book investigates collisions occurring in the motion of solids, in the motion of fluids but also in the motion of pedestrians in crowds. The duration of these presented collisions is short compared to the whole duration of the motion: they are assumed instantaneous. The innovative concept demonstrated in this book is that a system made of two solids, is deformable because their relative position changes. The definition of the velocities of deformation of the system introduced in the classical developments of mechanics, the principle of the virtual work and the laws of thermodynamics, allows a large range of applications such as crowd motions, debris flow motions, and shape memory alloys motions. The set of the applications is even larger: social sciences and mechanics are unified to predict the motion of crowds with application to transport management and to evacuation of theaters management.

  15. Collisions engineering theory and applications

    CERN Document Server

    Frémond, Michel

    2017-01-01

    This book investigates collisions occurring in the motion of solids, in the motion of fluids but also in the motion of pedestrians in crowds. The duration of these presented collisions is short compared to the whole duration of the motion: they are assumed instantaneous. The innovative concept demonstrated in this book is that a system made of two solids, is deformable because their relative position changes. The definition of the velocities of deformation of the system introduced in the classical developments of mechanics, the principle of the virtual work and the laws of thermodynamics, allows a large range of applications such as crowd motions, debris flow motions, and shape memory alloys motions. The set of the applications is even larger: social sciences and mechanics are unified to predict the motion of crowds with application to transport management and to evacuation of theaters management.

  16. Social Engineering Attack Detection Model: SEADMv2

    CSIR Research Space (South Africa)

    Mouton, F

    2015-10-01

    Full Text Available link in the security chain. A social engineering attack targets this weakness by using various manipulation techniques to elicit individuals to perform sensitive requests. The field of social engineering is still in its infancy as far as formal...

  17. Practical Application of Sociology in Systems Engineering

    Science.gov (United States)

    Watson, Michael D.; Andrews, James G.; Eckley, Jeri Cassel; Culver, Michael L.

    2017-01-01

    Systems engineering involves both the integration of the system and the integration of the disciplines which develop and operate the system. Integrating the disciplines is a sociological effort to bring together different groups, who often have different terminology, to achieve a common goal, the system. The focus for the systems engineer is information flow through the organization, between the disciplines, to ensure the system is developed and operated will all relevant information informing system decisions. The practical application of the sociology in systems engineering brings in various organizational development concepts including the principles of planned renegotiation and the application of principles to address information barriers created by organizational culture. Concepts such as specification of ignorance, consistent terminology, opportunity structures, role-sets, and the reclama (reconsideration) process are all important sociological approaches that help address the organizational social structure (culture). In bringing the disciplines together, the systems engineer must also be wary of social ambivalence, social anomie, social dysfunction, and insider-outsider behavior. Unintended consequences can result when these social issues are present. These issues can occur when localized subcultures shift from the overarching organizational culture, or when the organizational culture prevents achievement of system goals. These sociological principles provide the systems engineer with key approaches to manage the information flow through the organization as the disciplines are integrated and share their information and provides key sociological barriers to information flow through the organization. This paper will discuss the practical application of sociological principles to systems engineering.

  18. Photonics Applications and Web Engineering: WILGA 2017

    Science.gov (United States)

    Romaniuk, Ryszard S.

    2017-08-01

    XLth Wilga Summer 2017 Symposium on Photonics Applications and Web Engineering was held on 28 May-4 June 2017. The Symposium gathered over 350 participants, mainly young researchers active in optics, optoelectronics, photonics, modern optics, mechatronics, applied physics, electronics technologies and applications. There were presented around 300 oral and poster papers in a few main topical tracks, which are traditional for Wilga, including: bio-photonics, optical sensory networks, photonics-electronics-mechatronics co-design and integration, large functional system design and maintenance, Internet of Things, measurement systems for astronomy, high energy physics experiments, and other. The paper is a traditional introduction to the 2017 WILGA Summer Symposium Proceedings, and digests some of the Symposium chosen key presentations. This year Symposium was divided to the following topical sessions/conferences: Optics, Optoelectronics and Photonics, Computational and Artificial Intelligence, Biomedical Applications, Astronomical and High Energy Physics Experiments Applications, Material Research and Engineering, and Advanced Photonics and Electronics Applications in Research and Industry.

  19. Optimization strategies for complex engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Eldred, M.S.

    1998-02-01

    LDRD research activities have focused on increasing the robustness and efficiency of optimization studies for computationally complex engineering problems. Engineering applications can be characterized by extreme computational expense, lack of gradient information, discrete parameters, non-converging simulations, and nonsmooth, multimodal, and discontinuous response variations. Guided by these challenges, the LDRD research activities have developed application-specific techniques, fundamental optimization algorithms, multilevel hybrid and sequential approximate optimization strategies, parallel processing approaches, and automatic differentiation and adjoint augmentation methods. This report surveys these activities and summarizes the key findings and recommendations.

  20. DESIGN QUALITY IN MECHANICAL ENGINEERING APPLICATION

    Directory of Open Access Journals (Sweden)

    Ayşegül Akdogan Eker

    2010-09-01

    Full Text Available There is a close relationship between material chose and quality in mechanical engineering application like there is in all the other engineering applications. If this relation is balanced then engineering success increases. Material chose comes to fore in the design process most of the time. The two most important responsibilities of the design engineer in here is to chose suitable material and to know the production processes about design. The chose of material of a design that will fulfill the needs all through its life has great importance. It is needed to limit the material applicants by choosing the most suitable ones among variable material. Choosing materials that were examined before and whose behavior is well known provides the designer to feel confident. However since using highly successful materials would increase the competitive power of the designs; designers should follow the developments in materials and know the features of new materials. The description of these features can be interpreted within quality. Quality from the point of engineer is the total fulfillment of expectations.Engineer today are faced with very important problems such as fast technological innovations, a dynamic socio-economical environment, global rivalry. One of the life buoys they stick while trying to solve these problems is total method of quality control. Total Quality model which can provide higher competitive power compared to classical management model brings success only when applied with its whole components. "Approach toward prevention" and "measurement and statistics" have an important place among these elements. The first step of the approach toward prevention composes of design quality and Quality Function Deployment (QFD, or in other words The House of Quality method that will provide this. In this paper; considering the quality function deployment, how the chose of material are done in mechanical engineering applications will be explained.

  1. Foam engineering fundamentals and applications

    CERN Document Server

    2012-01-01

    Containing contributions from leading academic and industrial researchers, this book provides a much needed update of foam science research. The first section of the book presents an accessible summary of the theory and fundamentals of foams. This includes chapters on morphology, drainage, Ostwald ripening, coalescence, rheology, and pneumatic foams. The second section demonstrates how this theory is used in a wide range of industrial applications, including foam fractionation, froth flotation and foam mitigation. It includes chapters on suprafroths, flotation of oil sands, foams in enhancing petroleum recovery, Gas-liquid Mass Transfer in foam, foams in glass manufacturing, fire-fighting foam technology and consumer product foams.

  2. Engineering Stem Cells for Biomedical Applications

    Science.gov (United States)

    Yin, Perry T.; Han, Edward

    2018-01-01

    Stem cells are characterized by a number of useful properties, including their ability to migrate, differentiate, and secrete a variety of therapeutic molecules such as immunomodulatory factors. As such, numerous pre-clinical and clinical studies have utilized stem cell-based therapies and demonstrated their tremendous potential for the treatment of various human diseases and disorders. Recently, efforts have focused on engineering stem cells in order to further enhance their innate abilities as well as to confer them with new functionalities, which can then be used in various biomedical applications. These engineered stem cells can take on a number of forms. For instance, engineered stem cells encompass the genetic modification of stem cells as well as the use of stem cells for gene delivery, nanoparticle loading and delivery, and even small molecule drug delivery. The present Review gives an in-depth account of the current status of engineered stem cells, including potential cell sources, the most common methods used to engineer stem cells, and the utilization of engineered stem cells in various biomedical applications, with a particular focus on tissue regeneration, the treatment of immunodeficiency diseases, and cancer. PMID:25772134

  3. Engineering Stem Cells for Biomedical Applications.

    Science.gov (United States)

    Yin, Perry T; Han, Edward; Lee, Ki-Bum

    2016-01-07

    Stem cells are characterized by a number of useful properties, including their ability to migrate, differentiate, and secrete a variety of therapeutic molecules such as immunomodulatory factors. As such, numerous pre-clinical and clinical studies have utilized stem cell-based therapies and demonstrated their tremendous potential for the treatment of various human diseases and disorders. Recently, efforts have focused on engineering stem cells in order to further enhance their innate abilities as well as to confer them with new functionalities, which can then be used in various biomedical applications. These engineered stem cells can take on a number of forms. For instance, engineered stem cells encompass the genetic modification of stem cells as well as the use of stem cells for gene delivery, nanoparticle loading and delivery, and even small molecule drug delivery. The present Review gives an in-depth account of the current status of engineered stem cells, including potential cell sources, the most common methods used to engineer stem cells, and the utilization of engineered stem cells in various biomedical applications, with a particular focus on tissue regeneration, the treatment of immunodeficiency diseases, and cancer. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  4. Thermal barrier coatings application in diesel engines

    Science.gov (United States)

    Fairbanks, J. W.

    1995-01-01

    Commercial use of thermal barrier coatings in diesel engines began in the mid 70's by Dr. Ingard Kvernes at the Central Institute for Industrial Research in Oslo, Norway. Dr. Kvernes attributed attack on diesel engine valves and piston crowns encountered in marine diesel engines in Norwegian ships as hot-corrosion attributed to a reduced quality of residual fuel. His solution was to coat these components to reduce metal temperature below the threshold of aggressive hot-corrosion and also provide protection. Roy Kamo introduced thermal barrier coatings in his 'Adiabatic Diesel Engine' in the late 70's. Kamo's concept was to eliminate the engine block water cooling system and reduce heat losses. Roy reported significant performance improvements in his thermally insulated engine at the SAE Congress in 1982. Kamo's work stimulates major programs with insulated engines, particularly in Europe. Most of the major diesel engine manufacturers conducted some level of test with insulated combustion chamber components. They initially ran into increased fuel consumption. The German engine consortium had Prof. Woschni of the Technical Institute in Munich. Woschni conducted testing with pistons with air gaps to provide the insulation effects. Woschni indicated the hot walls of the insulated engine created a major increase in heat transfer he refers to as 'convection vive.' Woschni's work was a major factor in the abrupt curtailment of insulated diesel engine work in continental Europe. Ricardo in the UK suggested that combustion should be reoptimized for the hot-wall effects of the insulated combustion chamber and showed under a narrow range of conditions fuel economy could be improved. The Department of Energy has supported thermal barrier coating development for diesel engine applications. In the Clean Diesel - 50 Percent Efficient (CD-50) engine for the year 2000, thermal barrier coatings will be used on piston crowns and possibly other components. The primary purpose of the

  5. Engineering applications of heuristic multilevel optimization methods

    Science.gov (United States)

    Barthelemy, Jean-Francois M.

    1989-01-01

    Some engineering applications of heuristic multilevel optimization methods are presented and the discussion focuses on the dependency matrix that indicates the relationship between problem functions and variables. Coordination of the subproblem optimizations is shown to be typically achieved through the use of exact or approximate sensitivity analysis. Areas for further development are identified.

  6. Electromyography physiology engineering and noninvasive applications

    CERN Document Server

    Parker, Philip; John Wiley & Sons

    2004-01-01

    "Featuring contributions from key innovators working in the field today, Electromyography reveals the broad applications of EMG data in areas as diverse as neurology, ergonomics, exercise physiology, rehabilitation, movement analysis, biofeedback, and myoelectric control of prostheses." "Electromyography offers physiologists, medical professionals, and students in biomedical engineering a new window into the possibilities of this technology."--Jacket.

  7. Recent Advances in Application of Biosensors in Tissue Engineering

    Science.gov (United States)

    Paul, Arghya; Lee, Yong-kyu; Jaffa, Ayad A.

    2014-01-01

    Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose, and H2O2 as well as serum proteins of large molecular size, such as albumin and alpha-fetoprotein, and inflammatory cytokines, such as IFN-g and TNF-α. In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications. PMID:25165697

  8. Recent Advances in Application of Biosensors in Tissue Engineering

    Directory of Open Access Journals (Sweden)

    Anwarul Hasan

    2014-01-01

    Full Text Available Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose, and H2O2 as well as serum proteins of large molecular size, such as albumin and alpha-fetoprotein, and inflammatory cytokines, such as IFN-g and TNF-α. In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications.

  9. Diesel Engine Valve Clearance Detection Using Acoustic Emission

    Directory of Open Access Journals (Sweden)

    Fathi Elamin

    2010-01-01

    Full Text Available This paper investigated, using experimental method, the suitability of acoustic emission (AE technique for the condition monitoring of diesel engine valve faults. The clearance fault was adjusted experimentally in an exhaust valve and successfully detected and diagnosed in a Ford FSD 425 four-cylinder, four-stroke, in-line OHV, direct injection diesel engine. The effect of faulty exhaust valve clearance on engine performance was monitored and the difference between the healthy and faulty engine was observed from the recorded AE signals. The measured results from this technique show that using only time domain and frequency domain analysis of acoustic emission signals can give a superior measure of engine condition. This concludes that acoustic emission is a powerful and reliable method of detection and diagnosis of the faults in diesel engines and this is considered to be a unique approach to condition monitoring of valve performance.

  10. Application of smart transmitter technology in nuclear engineering measurements

    International Nuclear Information System (INIS)

    Kang, Hyun Gook; Seong, Poong Hyun

    1993-01-01

    By making use of the microprocessor technology, instrumentation system becomes intelligent. In this study a programmable smart transmitter is designed and applied to the nuclear engineering measurements. In order to apply the smart transmitter technology to nuclear engineering measurements, the digital time delay compensation function and water level change detection function are developed and applied in this work. The time compensation function compensates effectively the time delay of the measured signal, but it is found that the characteristics of the compensation function should be considered through its application. It is also found that the water level change detection function reduces the detection time to about 7 seconds by the signal processing which has the time constant of over 250 seconds and which has the heavy noise. (Author)

  11. Detecting A Botnet By Reverse Engineering

    Directory of Open Access Journals (Sweden)

    Oesman Hendra Kelana

    2013-06-01

    Full Text Available Abstract— Botnet malware is a malicious program. Botnet that infects computers, called bots, will be controlled by a botmaster to do various things such as: spamming, phishing, keylogging Distributed Denial of Service (DDoS and other activities that are generally profitable to the owner of the bot (botmaster or those who use botnet services. The problem is that many computers have been controlled by botnets without the knowledge of the computer owner.  There are many ways to examine botnets, for example by studying the traffic from the botnet network, studying how botnets communicate to each, studying how each robot receives orders to do something, and so forth. Of the many methods, the most frequently and commonly used is the reverse engineering, where researchers study how a botnet works by botnet debugging. In this study the author tries to understand or research botnets by taking a type of botnet, namely Agobot, using reverse engineering.  One of the result of the research is that malware program files in general and in particular botnet has a technique to obscure the way that research using reverse engineering. Another result also shows that the botnet Agobot runs on computers by using the Windows service, and by changing the Windows registry so that every time the computer starts, Agobot always actively works in the computer memory. Keywords— Malware, Bot, Botnet, Botmaster, Agobot, Spam, Distributed Denial of Services, Identity Theft, Computer Security, Reverse Engineering, Debug, Windows Service, the Registry.

  12. Thermodynamic monitoring and misfunction detection in turbocharged diesel engines

    International Nuclear Information System (INIS)

    Milazzo, A.N.; Bidini, G.

    1992-01-01

    Many kinds of fault detection systems for reciprocating engines have been proposed. Mostly these systems rely on dynamic analysis of engine behavior or chemical analysis of exhaust. Very few systems achieve a real on line diagnosis. On the other hand, land based and aeronautic turbine power plants are mostly equipped with thermodynamic fault detection systems (gas path analysis). The authors are trying to design a simple, cheap and reliable diesel engine monitoring system, performing a real time, continuous service. State of the art dynamics, gas path analysis and some new ideas will be used. Here we present the first part of this project, dealing with thermodynamic engine analysis. Soon we hope to present also a different approach, relying on engine dynamic analysis. This paper is mainly concerned with diesel engines. It seems reasonable to concentrate ourselves on large and based engines, whose size and cost justify the implementation of a fault detection system. Anyway many results are fairly general, and could be used for smaller engines, like vehicle engines, and other cases in which large number of units can lower costs

  13. Engineering applications of microfocal radiography. Chapter 2

    International Nuclear Information System (INIS)

    Sharpe, R.S.; Parish, R.W.

    1980-01-01

    The engineering applications of microfocal radiography are reviewed in detail. After describing the terminology used, the types of application are identified where the advantages of the reduced focal spot size are utilised e.g. finer detail, dynamic radiography of temporally changing events, lower background in the film and superior depth of focus. The quality of the images obtained with microfocal techniques is also discussed in detail. Finally various types of microfocal equipment which are commercially available are described and explicit examples of the areas of application are given, e.g. non-destructive testing in the nuclear industry, microporosity in aero-engine gas turbine blades and inspection of miniaturised electronic components such as integrated circuits. (U.K.)

  14. Fault Detection for a Diesel Engine Actuator

    DEFF Research Database (Denmark)

    Blanke, M.; Bøgh, S.A.; Jørgensen, R.B.

    1995-01-01

    An electro-mechanical position servo is introduced as a benchmark for mode-based Fault Detection and Identification (FDI).......An electro-mechanical position servo is introduced as a benchmark for mode-based Fault Detection and Identification (FDI)....

  15. Practical applications of soft computing in engineering

    CERN Document Server

    2001-01-01

    Soft computing has been presented not only with the theoretical developments but also with a large variety of realistic applications to consumer products and industrial systems. Application of soft computing has provided the opportunity to integrate human-like vagueness and real-life uncertainty into an otherwise hard computer program. This book highlights some of the recent developments in practical applications of soft computing in engineering problems. All the chapters have been sophisticatedly designed and revised by international experts to achieve wide but in-depth coverage. Contents: Au

  16. Application of diagnostic system for diesel engine

    International Nuclear Information System (INIS)

    Yoshinaga, Takeshi; Hayashi, Haruji; Usui, Hiromi; Tsuruzono, Atsuya; Matsuda, Takafumi

    2008-01-01

    The Japan Atomic Power Company (JAPC) began to implement Condition Based Maintenance (CBM) for rotating components (pumps, fans and electric motors) from 1999 and, also has begun to apply diesel engine diagnostic techniques at our three nuclear power plants since 2004. This paper provides a description of the CBM methods used for diesel engines in nuclear standby service, a summary of the procedures to introduce these diagnostic techniques to our nuclear power plants, and experience with the application of these methods to JAPC nuclear power plants. (author)

  17. Engineered cell manipulation for biomedical application

    CERN Document Server

    Akashi, Misturu; Matsusaki, Michiya

    2014-01-01

    This book is the first to summarize new technologies for engineered cell manipulation. The contents focus on control of cellular functions by nanomaterials and control of three-dimensional cell-cell interactions. Control of cellular functions is important for cell differentiation, maturation, and activation, which generally are controlled by the addition of soluble cytokines or growth factors into cell culture dishes. Target antigen molecules can be efficiently delivered to the cytosol of the dendritic cells using the nanoparticle technique described here, and cellular functions such as dendritic cell maturation can be controlled easily and with precision. This book describes basic preparation of the nanoparticles, activation control of dendritic cells, immune function control, and in vivo application for various vaccination systems. The second type of control,that of cell-cell interaction, is important for tissue engineering in order to develop three-dimensional cellular constructs. To achieve in vitro engin...

  18. Pendant chain engineering to fine-tune the nanomorphologies and solid state luminescence of naphthalimide AIEEgens: application to phenolic nitro-explosive detection in water.

    Science.gov (United States)

    Meher, Niranjan; Iyer, Parameswar Krishnan

    2017-06-08

    Strategically, a series of five angular "V" shaped naphthalimide AIEEgens with varying pendant chains (butyl, hexyl, octyl, cyclohexyl and methylcyclohexyl) have been synthesized to fine-tune their nanomorphological and photophysical properties. With similar aromatic cores and electronic states, unexpected tuning of the condensed state emission colors and nanomorphologies (reproducible on any kind of surface) of naphthalimides has been achieved for the first time simply by varying their side chains. Conclusive analysis by various spectroscopic techniques (SC-XRD, powder-XRD, DLS, FESEM) and DFT computational studies confirmed the full control of the pendant chain (in terms of bulkiness around the naphthalimide core, which restricts the ease of intermolecular π-π interactions) over the nanoaggregate morphology and solid state emissive properties of the AIEEgens; this can be rationalized to all aggregation-prone systems. These comprehensive studies establish a conceptually unique yet simple and effective method to precisely tune the nanomorphologies and the emission colors of aggregation-prone small organic molecules by judicious choice of the non-conjugated pendant chain. Thus, considering the prime role of the active layer nanomorphology in all organic optoelectronic devices, this methodology may emerge as a promising tool to improve device performance. Among all the congeners, the hexyl chain-containing congener (HNQ) forms well-defined nanoribbons with smaller diameters (as confirmed from DLS: 166 nm and FESEM: 150 nm) and provides a larger surface area. Consequently, the HNQ-nanoribbons were employed as a fluorescent sensor for the discriminative detection of trinitrophenol (TNP) in pure aqueous media. FE-SEM images revealed that, upon gradual addition of TNP (10 nM to 100 μM), these nanoribbons undergo an aggregation/disaggregation process, forming non-fluorescent co-aggregates with TNP, and provide highly enhanced sensitivity compared to existing state

  19. Application of precision mechanical engineering techniques to the design of a moderate energy beam transport for the FAA explosive detection system

    International Nuclear Information System (INIS)

    Lujan, R.; Christensen, K.

    1993-01-01

    This paper discusses the application of precision mounting and alignment techniques to a moderate energy beam transport system (MEBT) used on the exit of a 1.75 MeV RFQ. While frequently found in optical systems, techniques-such-as kinematic mounting, and degree-of-freedom decoupling, are not as widely used for accelerator components. The MEBT consist of one permanent magnet quadrupole, four electro magnet quadrupole, and one debuncher cavity. Included in the paper are discussions of design and fabrication considerations as well as, installation, alignment and operations experience during the successful implementation on a working accelerator

  20. Engineered Proteins: Redox Properties and Their Applications

    Science.gov (United States)

    Prabhulkar, Shradha; Tian, Hui; Wang, Xiaotang; Zhu, Jun-Jie

    2012-01-01

    Abstract Oxidoreductases and metalloproteins, representing more than one third of all known proteins, serve as significant catalysts for numerous biological processes that involve electron transfers such as photosynthesis, respiration, metabolism, and molecular signaling. The functional properties of the oxidoreductases/metalloproteins are determined by the nature of their redox centers. Protein engineering is a powerful approach that is used to incorporate biological and abiological redox cofactors as well as novel enzymes and redox proteins with predictable structures and desirable functions for important biological and chemical applications. The methods of protein engineering, mainly rational design, directed evolution, protein surface modifications, and domain shuffling, have allowed the creation and study of a number of redox proteins. This review presents a selection of engineered redox proteins achieved through these methods, resulting in a manipulation in redox potentials, an increase in electron-transfer efficiency, and an expansion of native proteins by de novo design. Such engineered/modified redox proteins with desired properties have led to a broad spectrum of practical applications, ranging from biosensors, biofuel cells, to pharmaceuticals and hybrid catalysis. Glucose biosensors are one of the most successful products in enzyme electrochemistry, with reconstituted glucose oxidase achieving effective electrical communication with the sensor electrode; direct electron-transfer-type biofuel cells are developed to avoid thermodynamic loss and mediator leakage; and fusion proteins of P450s and redox partners make the biocatalytic generation of drug metabolites possible. In summary, this review includes the properties and applications of the engineered redox proteins as well as their significance and great potential in the exploration of bioelectrochemical sensing devices. Antioxid. Redox Signal. 17, 1796–1822. PMID:22435347

  1. Application of Formal Methods in Software Engineering

    Directory of Open Access Journals (Sweden)

    Adriana Morales

    2011-12-01

    Full Text Available The purpose of this research work is to examine: (1 why are necessary the formal methods for software systems today, (2 high integrity systems through the methodology C-by-C –Correctness-by-Construction–, and (3 an affordable methodology to apply formal methods in software engineering. The research process included reviews of the literature through Internet, in publications and presentations in events. Among the Research results found that: (1 there is increasing the dependence that the nations have, the companies and people of software systems, (2 there is growing demand for software Engineering to increase social trust in the software systems, (3 exist methodologies, as C-by-C, that can provide that level of trust, (4 Formal Methods constitute a principle of computer science that can be applied software engineering to perform reliable process in software development, (5 software users have the responsibility to demand reliable software products, and (6 software engineers have the responsibility to develop reliable software products. Furthermore, it is concluded that: (1 it takes more research to identify and analyze other methodologies and tools that provide process to apply the Formal Software Engineering methods, (2 Formal Methods provide an unprecedented ability to increase the trust in the exactitude of the software products and (3 by development of new methodologies and tools is being achieved costs are not more a disadvantage for application of formal methods.

  2. Pulmonary applications and toxicity of engineered nanoparticles

    OpenAIRE

    Card, Jeffrey W.; Zeldin, Darryl C.; Bonner, James C.; Nestmann, Earle R.

    2008-01-01

    Because of their unique physicochemical properties, engineered nanoparticles have the potential to significantly impact respiratory research and medicine by means of improving imaging capability and drug delivery, among other applications. These same properties, however, present potential safety concerns, and there is accumulating evidence to suggest that nanoparticles may exert adverse effects on pulmonary structure and function. The respiratory system is susceptible to injury resulting from...

  3. Engineering noble metal nanomaterials for environmental applications

    Science.gov (United States)

    Li, Jingguo; Zhao, Tingting; Chen, Tiankai; Liu, Yanbiao; Ong, Choon Nam; Xie, Jianping

    2015-04-01

    Besides being valuable assets in our daily lives, noble metals (namely, gold, silver, and platinum) also feature many intriguing physical and chemical properties when their sizes are reduced to the nano- or even subnano-scale; such assets may significantly increase the values of the noble metals as functional materials for tackling important societal issues related to human health and the environment. Among which, designing/engineering of noble metal nanomaterials (NMNs) to address challenging issues in the environment has attracted recent interest in the community. In general, the use of NMNs for environmental applications is highly dependent on the physical and chemical properties of NMNs. Such properties can be readily controlled by tailoring the attributes of NMNs, including their size, shape, composition, and surface. In this feature article, we discuss recent progress in the rational design and engineering of NMNs with particular focus on their applications in the field of environmental sensing and catalysis. The development of functional NMNs for environmental applications is highly interdisciplinary, which requires concerted efforts from the communities of materials science, chemistry, engineering, and environmental science.

  4. Engineering noble metal nanomaterials for environmental applications.

    Science.gov (United States)

    Li, Jingguo; Zhao, Tingting; Chen, Tiankai; Liu, Yanbiao; Ong, Choon Nam; Xie, Jianping

    2015-05-07

    Besides being valuable assets in our daily lives, noble metals (namely, gold, silver, and platinum) also feature many intriguing physical and chemical properties when their sizes are reduced to the nano- or even subnano-scale; such assets may significantly increase the values of the noble metals as functional materials for tackling important societal issues related to human health and the environment. Among which, designing/engineering of noble metal nanomaterials (NMNs) to address challenging issues in the environment has attracted recent interest in the community. In general, the use of NMNs for environmental applications is highly dependent on the physical and chemical properties of NMNs. Such properties can be readily controlled by tailoring the attributes of NMNs, including their size, shape, composition, and surface. In this feature article, we discuss recent progress in the rational design and engineering of NMNs with particular focus on their applications in the field of environmental sensing and catalysis. The development of functional NMNs for environmental applications is highly interdisciplinary, which requires concerted efforts from the communities of materials science, chemistry, engineering, and environmental science.

  5. Application engineering for process computer systems

    International Nuclear Information System (INIS)

    Mueller, K.

    1975-01-01

    The variety of tasks for process computers in nuclear power stations necessitates the centralization of all production stages from the planning stage to the delivery of the finished process computer system (PRA) to the user. This so-called 'application engineering' comprises all of the activities connected with the application of the PRA: a) establishment of the PRA concept, b) project counselling, c) handling of offers, d) handling of orders, e) internal handling of orders, f) technical counselling, g) establishing of parameters, h) monitoring deadlines, i) training of customers, j) compiling an operation manual. (orig./AK) [de

  6. Heat transfer applications for the practicing engineer

    CERN Document Server

    Theodore, Louis

    2011-01-01

    This book serves as a training tool for individuals in industry and academia involved with heat transfer applications. Although the literature is inundated with texts emphasizing theory and theoretical derivations, the goal of this book is to present the subject of heat transfer from a strictly pragmatic point of view. The book is divided into four Parts: Introduction, Principles, Equipment Design Procedures and Applications, and ABET-related Topics. The first Part provides a series of chapters concerned with introductory topics that are required when solving most engineering problems, inclu

  7. TMTI Task 1.6 Genetic Engineering Methods and Detection

    Energy Technology Data Exchange (ETDEWEB)

    Slezak, T; Lenhoff, R; Allen, J; Borucki, M; Vitalis, E; Gardner, S

    2009-12-04

    A large number of GE techniques can be adapted from other microorganisms to biothreat bacteria and viruses. Detection of GE in a microorganism increases in difficulty as the size of the genetic change decreases. In addition to the size of the engineered change, the consensus genomic sequence of the microorganism can impact the difficulty of detecting an engineered change in genomes that are highly variable from strain to strain. This problem will require comprehensive databases of whole genome sequences for more genetically variable biothreat bacteria and viruses. Preliminary work with microarrays for detecting synthetic elements or virulence genes and analytic bioinformatic approaches for whole genome sequence comparison to detect genetic engineering show promise for attacking this difficult problem but a large amount of future work remains.

  8. Engineering thermal engine rocket adventurer for space nuclear application

    International Nuclear Information System (INIS)

    Nam, Seung H.; Suh, Kune Y.; Kang, Seong G.

    2008-01-01

    The conceptual design for the first-of-a-kind engineering of Thermal Engine Rocket Adventure (TERA) is described. TERA comprising the Battery Omnibus Reactor Integral System (BORIS) as the heat resource and the Space Propulsion Reactor Integral System (SPRIS) as the propulsion system, is one of the advanced Nuclear Thermal Rocket (NTR) engine utilizing hydrogen (H 2 ) propellant being developed at present time. BORIS in this application is an open cycle high temperature gas cooled reactor that has eighteen fuel elements for propulsion and one fuel element for electricity generation and propellant pumping. Each fuel element for propulsion has its own small nozzle. The nineteen fuel elements are arranged into hexagonal prism shape in the core and surrounded by outer Be reflector. The TERA maximum power is 1,000 MW th , specific impulse 1,000 s, thrust 250,000 N, and the total mass is 550 kg including the reactor, turbo pump and auxiliaries. Each fuel element comprises the fuel assembly, moderators, pressure tube and small nozzle. The TERA fuel assembly is fabricated of 93% enriched 1.5 mm (U, Zr, Nb)C wafers in 25.3% voided Square Lattice Honeycomb (SLHC). The H 2 propellant passes through these flow channels. This study is concerned with thermohydrodynamic analysis of the fuel element for propulsion with hypothetical axial power distribution because nuclear analysis of TERA has not been performed yet. As a result, when the power distribution of INSPI's M-SLHC is applied to the fuel assembly, the local heat concentration of fuel is more serious and the pressure of the initial inlet H 2 is higher than those of constant average power distribution applied. This means the fuel assembly geometry of 1.5 mm fuel wafers and 25.3% voided SLHC needs to be changed in order to reduce thermal and mechanical shocks. (author)

  9. Electrospinning of Nanofibers for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Haifeng Liu

    2013-01-01

    Full Text Available Electrospinning is a method in which materials in solution are formed into nano- and micro-sized continuous fibers. Recent interest in this technique stems from both the topical nature of nanoscale material fabrication and the considerable potential for use of these nanoscale fibres in a range of applications including, amongst others, a range of biomedical applications processes such as drug delivery and the use of scaffolds to provide a framework for tissue regeneration in both soft and hard tissue applications systems. The objectives of this review are to describe the theory behind the technique, examine the effect of changing the process parameters on fiber morphology, and discuss the application and impact of electrospinning on the fields of vascular, neural, bone, cartilage, and tendon/ligament tissue engineering.

  10. Radioactivity source terms for underground engineering application

    Energy Technology Data Exchange (ETDEWEB)

    Tewes, H A [Lawrence Radiation Laboratory, Livermore, CA (United States)

    1969-07-01

    The constraints on nuclide production are usually very similar in any underground engineering application of nuclear explosives. However, in some applications the end product could be contaminated unless the proper nuclear device is used. This fact can be illustrated from two underground engineering experiments-Gasbuggy and Sloop. In the Gasbuggy experiment, appreciable tritium has been shown to be present in the gas currently being produced. However, in future gas stimulation applications (as distinct from experiments), a minimum production of tritium by the explosive is desirable since product contamination by this nuclide may place severe limitations on the use of the tritiated gas. In Sloop, where production of copper is the goal of the experiment, product contamination would not be caused by tritium but could result from other nuclides: Thus, gas stimulation could require the use of fission explosives while the lower cost per kiloton of thermonuclear explosives could make them attractive for ore-crushing applications. Because of this consideration, radionuclide production calculations must be made for both fission and for thermonuclear explosives in the underground environment. Such activation calculations materials of construction are performed in a manner similar to that described in another paper, but radionuclide production in the environment must be computed using both fission neutron and 14-MeV neutron sources in order to treat the 'source term' problem realistically. In making such computations, parameter studies including the effects of environmental temperature, neutron shielding, and rock types have been carried out. Results indicate the importance of carefully evaluating the radionuclide production for each individual underground engineering application. (author)

  11. Radioactivity source terms for underground engineering application

    International Nuclear Information System (INIS)

    Tewes, H.A.

    1969-01-01

    The constraints on nuclide production are usually very similar in any underground engineering application of nuclear explosives. However, in some applications the end product could be contaminated unless the proper nuclear device is used. This fact can be illustrated from two underground engineering experiments-Gasbuggy and Sloop. In the Gasbuggy experiment, appreciable tritium has been shown to be present in the gas currently being produced. However, in future gas stimulation applications (as distinct from experiments), a minimum production of tritium by the explosive is desirable since product contamination by this nuclide may place severe limitations on the use of the tritiated gas. In Sloop, where production of copper is the goal of the experiment, product contamination would not be caused by tritium but could result from other nuclides: Thus, gas stimulation could require the use of fission explosives while the lower cost per kiloton of thermonuclear explosives could make them attractive for ore-crushing applications. Because of this consideration, radionuclide production calculations must be made for both fission and for thermonuclear explosives in the underground environment. Such activation calculations materials of construction are performed in a manner similar to that described in another paper, but radionuclide production in the environment must be computed using both fission neutron and 14-MeV neutron sources in order to treat the 'source term' problem realistically. In making such computations, parameter studies including the effects of environmental temperature, neutron shielding, and rock types have been carried out. Results indicate the importance of carefully evaluating the radionuclide production for each individual underground engineering application. (author)

  12. Electrospun polyurethane membranes for Tissue Engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Gabriel, Laís P., E-mail: lagabriel@gmail.com [National Institute of Biofabrication, Campinas (Brazil); Department of Chemical Engineering, University of Campinas, Campinas (Brazil); Rodrigues, Ana Amélia [National Institute of Biofabrication, Campinas (Brazil); Department of Medical Sciences, University of Campinas, Campinas (Brazil); Macedo, Milton; Jardini, André L.; Maciel Filho, Rubens [National Institute of Biofabrication, Campinas (Brazil); Department of Chemical Engineering, University of Campinas, Campinas (Brazil)

    2017-03-01

    Tissue Engineering proposes, among other things, tissue regeneration using scaffolds integrated with biological molecules, growth factors or cells for such regeneration. In this research, polyurethane membranes were prepared using the electrospinning technique in order to obtain membranes to be applied in Tissue Engineering, such as epithelial, drug delivery or cardiac applications. The influence of fibers on the structure and morphology of the membranes was studied using scanning electron microscopy (SEM), the structure was evaluated by Fourier transform infrared spectroscopy (FT-IR), and the thermal stability was analyzed by thermogravimetry analysis (TGA). In vitro cells attachment and proliferation was investigated by SEM, and in vitro cell viability was studied by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays and Live/Dead® assays. It was found that the membranes present an homogeneous morphology, high porosity, high surface area/volume ratio, it was also observed a random fiber network. The thermal analysis showed that the membrane degradation started at 254 °C. In vitro evaluation of fibroblasts cells showed that fibroblasts spread over the membrane surface after 24, 48 and 72 h of culture. This study supports the investigation of electrospun polyurethane membranes as biocompatible scaffolds for Tissue Engineering applications and provides some guidelines for improved biomaterials with desired properties.

  13. Sonic IR crack detection of aircraft turbine engine blades with multi-frequency ultrasound excitations

    International Nuclear Information System (INIS)

    Zhang, Ding; Han, Xiaoyan; Newaz, Golam

    2014-01-01

    Effectively and accurately detecting cracks or defects in critical engine components, such as turbine engine blades, is very important for aircraft safety. Sonic Infrared (IR) Imaging is such a technology with great potential for these applications. This technology combines ultrasound excitation and IR imaging to identify cracks and flaws in targets. In general, failure of engine components, such as blades, begins with tiny cracks. Since the attenuation of the ultrasound wave propagation in turbine engine blades is small, the efficiency of crack detection in turbine engine blades can be quite high. The authors at Wayne State University have been developing the technology as a reliable tool for the future field use in aircraft engines and engine parts. One part of the development is to use finite element modeling to assist our understanding of effects of different parameters on crack heating while experimentally hard to achieve. The development has been focused with single frequency ultrasound excitation and some results have been presented in a previous conference. We are currently working on multi-frequency excitation models. The study will provide results and insights of the efficiency of different frequency excitation sources to foster the development of the technology for crack detection in aircraft engine components

  14. Vision systems for scientific and engineering applications

    International Nuclear Information System (INIS)

    Chadda, V.K.

    2009-01-01

    Human performance can get degraded due to boredom, distraction and fatigue in vision-related tasks such as measurement, counting etc. Vision based techniques are increasingly being employed in many scientific and engineering applications. Notable advances in this field are emerging from continuing improvements in the fields of sensors and related technologies, and advances in computer hardware and software. Automation utilizing vision-based systems can perform repetitive tasks faster and more accurately, with greater consistency over time than humans. Electronics and Instrumentation Services Division has developed vision-based systems for several applications to perform tasks such as precision alignment, biometric access control, measurement, counting etc. This paper describes in brief four such applications. (author)

  15. A Comparison of Source Code Plagiarism Detection Engines

    Science.gov (United States)

    Lancaster, Thomas; Culwin, Fintan

    2004-06-01

    Automated techniques for finding plagiarism in student source code submissions have been in use for over 20 years and there are many available engines and services. This paper reviews the literature on the major modern detection engines, providing a comparison of them based upon the metrics and techniques they deploy. Generally the most common and effective techniques are seen to involve tokenising student submissions then searching pairs of submissions for long common substrings, an example of what is defined to be a paired structural metric. Computing academics are recommended to use one of the two Web-based detection engines, MOSS and JPlag. It is shown that whilst detection is well established there are still places where further research would be useful, particularly where visual support of the investigation process is possible.

  16. Conformal geometry computational algorithms and engineering applications

    CERN Document Server

    Jin, Miao; He, Ying; Wang, Yalin

    2018-01-01

    This book offers an essential overview of computational conformal geometry applied to fundamental problems in specific engineering fields. It introduces readers to conformal geometry theory and discusses implementation issues from an engineering perspective.  The respective chapters explore fundamental problems in specific fields of application, and detail how computational conformal geometric methods can be used to solve them in a theoretically elegant and computationally efficient way. The fields covered include computer graphics, computer vision, geometric modeling, medical imaging, and wireless sensor networks. Each chapter concludes with a summary of the material covered and suggestions for further reading, and numerous illustrations and computational algorithms complement the text.  The book draws on courses given by the authors at the University of Louisiana at Lafayette, the State University of New York at Stony Brook, and Tsinghua University, and will be of interest to senior undergraduates, gradua...

  17. Incipient failure detection of space shuttle main engine turbopump bearings using vibration envelope detection

    Science.gov (United States)

    Hopson, Charles B.

    1987-01-01

    The results of an analysis performed on seven successive Space Shuttle Main Engine (SSME) static test firings, utilizing envelope detection of external accelerometer data are discussed. The results clearly show the great potential for using envelope detection techniques in SSME incipient failure detection.

  18. Engineering growth factors for regenerative medicine applications.

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Aaron C.; Briquez, Priscilla S.; Hubbell, Jeffrey A.; Cochran, Jennifer R.

    2016-01-15

    Growth factors are important morphogenetic proteins that instruct cell behavior and guide tissue repair and renewal. Although their therapeutic potential holds great promise in regenerative medicine applications, translation of growth factors into clinical treatments has been hindered by limitations including poor protein stability, low recombinant expression yield, and suboptimal efficacy. This review highlights current tools, technologies, and approaches to design integrated and effective growth factor-based therapies for regenerative medicine applications. The first section describes rational and combinatorial protein engineering approaches that have been utilized to improve growth factor stability, expression yield, biodistribution, and serum half-life, or alter their cell trafficking behavior or receptor binding affinity. The second section highlights elegant biomaterial-based systems, inspired by the natural extracellular matrix milieu, that have been developed for effective spatial and temporal delivery of growth factors to cell surface receptors. Although appearing distinct, these two approaches are highly complementary and involve principles of molecular design and engineering to be considered in parallel when developing optimal materials for clinical applications.

  19. Fast radial basis functions for engineering applications

    CERN Document Server

    Biancolini, Marco Evangelos

    2017-01-01

    This book presents the first “How To” guide to the use of radial basis functions (RBF). It provides a clear vision of their potential, an overview of ready-for-use computational tools and precise guidelines to implement new engineering applications of RBF. Radial basis functions (RBF) are a mathematical tool mature enough for useful engineering applications. Their mathematical foundation is well established and the tool has proven to be effective in many fields, as the mathematical framework can be adapted in several ways. A candidate application can be faced considering the features of RBF:  multidimensional space (including 2D and 3D), numerous radial functions available, global and compact support, interpolation/regression. This great flexibility makes RBF attractive – and their great potential has only been partially discovered. This is because of the difficulty in taking a first step toward RBF as they are not commonly part of engineers’ cultural background, but also due to the numerical complex...

  20. Unconventional applications of conventional intrusion detection sensors

    International Nuclear Information System (INIS)

    Williams, J.D.; Matter, J.C.

    1983-01-01

    A number of conventional intrusion detection sensors exists for the detection of persons entering buildings, moving within a given volume, and crossing a perimeter isolation zone. Unconventional applications of some of these sensors have recently been investigated. Some of the applications which are discussed include detection on the edges and tops of buildings, detection in storm sewers, detection on steam and other types of large pipes, and detection of unauthorized movement within secure enclosures. The enclosures can be used around complicated control valves, electrical control panels, emergency generators, etc

  1. Application of polarization OCT in tissue engineering

    Science.gov (United States)

    Yang, Ying; Ahearne, Mark; Bagnaninchi, Pierre O.; Hu, Bin; Hampson, Karen; El Haj, Alicia J.

    2008-02-01

    For tissue engineering of load-bearing tissues, such as bone, tendon, cartilage, and cornea, it is critical to generate a highly organized extracellular matrix. The major component of the matrix in these tissues is collagen, which usually forms a highly hierarchical structure with increasing scale from fibril to fiber bundles. These bundles are ordered into a 3D network to withstand forces such as tensile, compressive or shear. To induce the formation of organized matrix and create a mimic body environment for tissue engineering, in particular, tendon tissue engineering, we have fabricated scaffolds with features to support the formation of uniaxially orientated collagen bundles. In addition, mechanical stimuli were applied to stimulate tissue formation and matrix organization. In parallel, we seek a nondestructive tool to monitor the changes within the constructs in response to these external stimulations. Polarizationsensitive optical coherence tomography (PSOCT) is a non-destructive technique that provides functional imaging, and possesses the ability to assess in depth the organization of tissue. In this way, an engineered tissue construct can be monitored on-line, and correlated with the application of different stimuli by PSOCT. We have constructed a PSOCT using a superluminescent diode (FWHM 52nm) in this study and produced two types of tendon constructs. The matrix structural evolution under different mechanical stimulation has been evaluated by the PSOCT. The results in this study demonstrate that PSOCT was a powerful tool enabling us to monitor non-destructively and real time the progressive changes in matrix organization and assess the impact of various stimuli on tissue orientation and growth.

  2. Applications of laser diagnostics to thermal power plants and engines

    International Nuclear Information System (INIS)

    Deguchi, Y.; Kamimoto, T.; Wang, Z.Z.; Yan, J.J.; Liu, J.P.; Watanabe, H.; Kurose, R.

    2014-01-01

    The demands for lowering the burdens on the environment will continue to grow steadily. It is important to monitor controlling factors in order to improve the operation of industrial thermal systems. In engines, exhaust gas temperature and concentration distributions are important factors in nitrogen oxides (NO x ), total hydrocarbon (THC) and particulate matter (PM) emissions. Coal and fly ash contents are parameters which can be used for the control of coal-fired thermal power plants. Monitoring of heavy metals such as Hg is also important for pollution control. In this study, the improved laser measurement techniques using computed tomography-tunable diode laser absorption spectroscopy (CT-TDLAS), low pressure laser-induced breakdown spectroscopy (LIBS), and laser breakdown time-of-flight mass spectrometry (LB-TOFMS) have been developed and applied to measure 2D temperature and species concentrations in engine exhausts, coal and fly ash contents, and trace species measurement. The 2D temperature and NH 3 concentration distributions in engine exhausts were successfully measured using CT-TDLAS. The elemental contents of size-segregated particles were measured and the signal stability increased using LIBS with the temperature correction method. The detection limit of trace species measurement was enhanced using low pressure LIBS and LB-TOFMS. The detection limit of Hg can be enhanced to 3.5 ppb when employing N 2 as the buffer gas using low pressure LIBS. Hg detection limit was about 0.82 ppb using 35 ps LB-TOFMS. Compared to conventional measurement methods laser diagnostics has high sensitivity, high response and non-contact features for actual industrial systems. With these engineering developments, transient phenomena such as start-ups in thermal systems can be evaluated to improve the efficiency of these thermal processes. - Highlights: • Applicability of newly developed laser diagnostics was demonstrated for the improvement of thermal power plants and

  3. Application of systems engineering: An acquisition agent perspective

    CSIR Research Space (South Africa)

    Niken, A

    2014-09-01

    Full Text Available This article covers a descriptive case study on the application of systems engineering and systems engineering management at Armscor. The report also covers the investigation into development methods used and the how the requirements changes...

  4. Application of systems engineering: An acquisition agent perspective

    CSIR Research Space (South Africa)

    Niken, A

    2014-10-01

    Full Text Available This article covers a descriptive case study on the application of systems engineering and systems engineering management at Armscor. The report also covers the investigation into development methods used and the how the requirements changes...

  5. Applications of metaheuristic optimization algorithms in civil engineering

    CERN Document Server

    Kaveh, A

    2017-01-01

    The book presents recently developed efficient metaheuristic optimization algorithms and their applications for solving various optimization problems in civil engineering. The concepts can also be used for optimizing problems in mechanical and electrical engineering.

  6. Introduction to tissue engineering and application for cartilage engineering.

    Science.gov (United States)

    de Isla, N; Huseltein, C; Jessel, N; Pinzano, A; Decot, V; Magdalou, J; Bensoussan, D; Stoltz, J-F

    2010-01-01

    Tissue engineering is a multidisciplinary field that applies the principles of engineering, life sciences, cell and molecular biology toward the development of biological substitutes that restore, maintain, and improve tissue function. In Western Countries, tissues or cells management for clinical uses is a medical activity governed by different laws. Three general components are involved in tissue engineering: (1) reparative cells that can form a functional matrix; (2) an appropriate scaffold for transplantation and support; and (3) bioreactive molecules, such as cytokines and growth factors that will support and choreograph formation of the desired tissue. These three components may be used individually or in combination to regenerate organs or tissues. Thus the growing development of tissue engineering needs to solve four main problems: cells, engineering development, grafting and safety studies.

  7. Intelligent techniques in engineering management theory and applications

    CERN Document Server

    Onar, Sezi

    2015-01-01

    This book presents recently developed intelligent techniques with applications and theory in the area of engineering management. The involved applications of intelligent techniques such as neural networks, fuzzy sets, Tabu search, genetic algorithms, etc. will be useful for engineering managers, postgraduate students, researchers, and lecturers. The book has been written considering the contents of a classical engineering management book but intelligent techniques are used for handling the engineering management problem areas. This comprehensive characteristics of the book makes it an excellent reference for the solution of complex problems of engineering management. The authors of the chapters are well-known researchers with their previous works in the area of engineering management.

  8. Unsupervised Condition Change Detection In Large Diesel Engines

    DEFF Research Database (Denmark)

    Pontoppidan, Niels Henrik; Larsen, Jan

    2003-01-01

    This paper presents a new method for unsupervised change detection which combines independent component modeling and probabilistic outlier etection. The method further provides a compact data representation, which is amenable to interpretation, i.e., the detected condition changes can be investig...... be investigated further. The method is successfully applied to unsupervised condition change detection in large diesel engines from acoustical emission sensor signal and compared to more classical techniques based on principal component analysis and Gaussian mixture models.......This paper presents a new method for unsupervised change detection which combines independent component modeling and probabilistic outlier etection. The method further provides a compact data representation, which is amenable to interpretation, i.e., the detected condition changes can...

  9. Applications of artificial intelligence in engineering problems

    Energy Technology Data Exchange (ETDEWEB)

    Sriram, D; Adey, R

    1986-01-01

    This book presents the papers given at a conference on the use of artificial intelligence in engineering. Topics considered at the conference included Prolog logic, expert systems, knowledge representation and acquisition, knowledge bases, machine learning, robotics, least-square algorithms, vision systems for robots, natural language, probability, mechanical engineering, civil engineering, and electrical engineering.

  10. Software engineering processes principles and applications

    CERN Document Server

    Wang, Yingxu

    2000-01-01

    Fundamentals of the Software Engineering ProcessIntroductionA Unified Framework of the Software Engineering ProcessProcess AlgebraProcess-Based Software EngineeringSoftware Engineering Process System ModelingThe CMM ModelThe ISO 9001 ModelThe BOOTSTRAP ModelThe ISO/IEC 15504 (SPICE) ModelThe Software Engineering Process Reference Model: SEPRMSoftware Engineering Process System AnalysisBenchmarking the SEPRM ProcessesComparative Analysis of Current Process ModelsTransformation of Capability Levels Between Current Process ModelsSoftware Engineering Process EstablishmentSoftware Process Establish

  11. Internal Combustion Engine Principles with Vehicle Applications

    DEFF Research Database (Denmark)

    Sorenson, Spencer C

    The book is an introductory text on the subject of internal combustion engines, intended for use in engineering courses at the senior or introductory graduate student level. The focus in on describing the basic principles of engine operation on a broad basis, to provide a foundation for further...... exchange processes, combustion in different engine types, exhaust emissions, engine control including mean value engine models, pressure charging, fuels and fuel systems, balancing, friction, and heat transfer. In addition, methods to establish the connection between engine characteristics and vehicle...

  12. Civil engineering applications of ground penetrating radar

    CERN Document Server

    Pajewski, Lara

    2015-01-01

    This book, based on Transport and Urban Development COST Action TU1208, presents the most advanced applications of ground penetrating radar (GPR) in a civil engineering context, with documentation of instrumentation, methods, and results. It explains clearly how GPR can be employed for the surveying of critical transport infrastructure, such as roads, pavements, bridges, and tunnels, and for the sensing and mapping of underground utilities and voids. Detailed attention is also devoted to use of GPR in the inspection of geological structures and of construction materials and structures, including reinforced concrete, steel reinforcing bars, and pre/post-tensioned stressing ducts. Advanced methods for solution of electromagnetic scattering problems and new data processing techniques are also presented. Readers will come to appreciate that GPR is a safe, advanced, nondestructive, and noninvasive imaging technique that can be effectively used for the inspection of composite structures and the performance of diagn...

  13. Uncertainty Quantification with Applications to Engineering Problems

    DEFF Research Database (Denmark)

    Bigoni, Daniele

    in measurements, predictions and manufacturing, and we can say that any dynamical system used in engineering is subject to some of these uncertainties. The first part of this work presents an overview of the mathematical framework used in Uncertainty Quantification (UQ) analysis and introduces the spectral tensor...... and thus the UQ analysis of the associated systems will benefit greatly from the application of methods which require few function evaluations. We first consider the propagation of the uncertainty and the sensitivity analysis of the non-linear dynamics of railway vehicles with suspension components whose......-scale problems, where efficient methods are necessary with today’s computational resources. The outcome of this work was also the creation of several freely available Python modules for Uncertainty Quantification, which are listed and described in the appendix....

  14. Application of Internet in Road Traffic Engineering

    Directory of Open Access Journals (Sweden)

    Ivan Dadić

    2012-10-01

    Full Text Available The paper deals with the implementation of Internet in trafficengineering with the purpose of improving the professionaland scientific research development of the traffic system in theRepublic of Croatia.Fast growth of the world computer network, Internet, andits applications in almost all the fields of human activities,change the picture of the modern world. The current exchangeof data in all their forms and the daily growth of the network,supplemented by almost incredible amounts of data that can bealmost instantly accessible, indicates that Internet is not just theinfomwtion technology revolution, but that it is a revolutionper se. More than 100 million computers are estimated to benetworked beginning of the 21" century.Internet seems almost as if it were created for the purposesof knowledge and expe1ience exchange in traffic, a relativelyyoung scientific branch. 11 can be concluded that the presenceof traffic engineers in Internet is today's reality and tomon·ow'snecessity.

  15. Mobile Prototyping Platforms for Remote Engineering Applications

    Directory of Open Access Journals (Sweden)

    Karsten Henke

    2009-08-01

    Full Text Available This paper describes a low-cost mobile communication platform as a universal rapid-prototyping system, which is based on the Quadrocopter concept. At the Integrated Hardware and Software Systems Group at the Ilmenau University of Technology these mobile platforms are used to motivate bachelor and master students to study Computer Engineering sciences. This could be done by increasing their interest in technical issues, using this platform as integral part of a new ad-hoc lab to demonstrate different aspects in the area of Mobile Communication as well as universal rapid prototyping nodes to investigate different mechanisms for self-organized mobile communication systems within the International Graduate School on Mobile Communications. Beside the three fields of application, the paper describes the current architecture concept of the mobile prototyping platform as well as the chosen control mechanism and the assigned sensor systems to fulfill all the required tasks.

  16. Soft computing techniques in engineering applications

    CERN Document Server

    Zhong, Baojiang

    2014-01-01

    The Soft Computing techniques, which are based on the information processing of biological systems are now massively used in the area of pattern recognition, making prediction & planning, as well as acting on the environment. Ideally speaking, soft computing is not a subject of homogeneous concepts and techniques; rather, it is an amalgamation of distinct methods that confirms to its guiding principle. At present, the main aim of soft computing is to exploit the tolerance for imprecision and uncertainty to achieve tractability, robustness and low solutions cost. The principal constituents of soft computing techniques are probabilistic reasoning, fuzzy logic, neuro-computing, genetic algorithms, belief networks, chaotic systems, as well as learning theory. This book covers contributions from various authors to demonstrate the use of soft computing techniques in various applications of engineering.  

  17. Application of Chaos Theory to Engine Systems

    OpenAIRE

    Matsumoto, Kazuhiro; Diebner, Hans H.; Tsuda, Ichiro; Hosoi, Yukiharu

    2008-01-01

    We focus on the control issue for engine systems from the perspective of chaos theory, which is based on the fact that engine systems have a low-dimensional chaotic dynamics. Two approaches are discussed: controlling chaos and harnessing chaos, respectively. We apply Pyragas' chaos control method to an actual engine system. The experimental results show that the chaotic motion of an engine system may be stabilized to a periodic motion. Alternatively, harnessing chaos for engine systems is add...

  18. Nano-Engineered Hierarchical Advanced Composite Materials for Space Applications

    Data.gov (United States)

    National Aeronautics and Space Administration — Composites are widely used throughout aerospace engineering and in numerous other applications where structures that possess high strength and toughness properties...

  19. Engineering β-sheet peptide assemblies for biomedical applications.

    Science.gov (United States)

    Yu, Zhiqiang; Cai, Zheng; Chen, Qiling; Liu, Menghua; Ye, Ling; Ren, Jiaoyan; Liao, Wenzhen; Liu, Shuwen

    2016-03-01

    Hydrogels have been widely studied in various biomedical applications, such as tissue engineering, cell culture, immunotherapy and vaccines, and drug delivery. Peptide-based nanofibers represent a promising new strategy for current drug delivery approaches and cell carriers for tissue engineering. This review focuses on the recent advances in the use of self-assembling engineered β-sheet peptide assemblies for biomedical applications. The applications of peptide nanofibers in biomedical fields, such as drug delivery, tissue engineering, immunotherapy, and vaccines, are highlighted. The current challenges and future perspectives for self-assembling peptide nanofibers in biomedical applications are discussed.

  20. Molecularly engineered graphene surfaces for sensing applications: A review

    International Nuclear Information System (INIS)

    Liu, Jingquan; Liu, Zhen; Barrow, Colin J.; Yang, Wenrong

    2015-01-01

    Highlights: • The importance of surface chemistry of graphene materials is clearly described. • We discuss molecularly engineered graphene surfaces for sensing applications. • We describe the latest developments of these materials for sensing technology. - Abstract: Graphene is scientifically and commercially important because of its unique molecular structure which is monoatomic in thickness, rigorously two-dimensional and highly conjugated. Consequently, graphene exhibits exceptional electrical, optical, thermal and mechanical properties. Herein, we critically discuss the surface modification of graphene, the specific advantages that graphene-based materials can provide over other materials in sensor research and their related chemical and electrochemical properties. Furthermore, we describe the latest developments in the use of these materials for sensing technology, including chemical sensors and biosensors and their applications in security, environmental safety and diseases detection and diagnosis

  1. Molecularly engineered graphene surfaces for sensing applications: A review

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Jingquan, E-mail: jliu@qdu.edu.cn [College of Chemical Science and Engineering, Laboratory of Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao (China); Liu, Zhen; Barrow, Colin J. [Centre for Chemistry and Biotechnology, Deakin University, Geelong, VIC 3217 (Australia); Yang, Wenrong, E-mail: wenrong.yang@deakin.edu.au [Centre for Chemistry and Biotechnology, Deakin University, Geelong, VIC 3217 (Australia)

    2015-02-15

    Highlights: • The importance of surface chemistry of graphene materials is clearly described. • We discuss molecularly engineered graphene surfaces for sensing applications. • We describe the latest developments of these materials for sensing technology. - Abstract: Graphene is scientifically and commercially important because of its unique molecular structure which is monoatomic in thickness, rigorously two-dimensional and highly conjugated. Consequently, graphene exhibits exceptional electrical, optical, thermal and mechanical properties. Herein, we critically discuss the surface modification of graphene, the specific advantages that graphene-based materials can provide over other materials in sensor research and their related chemical and electrochemical properties. Furthermore, we describe the latest developments in the use of these materials for sensing technology, including chemical sensors and biosensors and their applications in security, environmental safety and diseases detection and diagnosis.

  2. Engineering applications using CAD based application programming interface

    Directory of Open Access Journals (Sweden)

    Tzotzis Anastasios

    2017-01-01

    Full Text Available Automating the design process of a product or a system can provide engineers and designers with many benefits. As such, repeatable tasks that are time consuming can be handled automatically and with minimal human attention. This is achieved by using the API (Application Programmable Interface of CAD systems in order to create macros or even develop software applications. The present paper deals with an application that has been developed with the API of a general purposes CAD system. This application automates the design process of a standard pneumatic double acting cylinder based on the appropriate inserted parameters (ISO 15552.The design process begins with the creation of a series of components developed as solids, and extends to the extraction of basic attributes and properties from the complete mechanical assembly. Finally, the assembled models and the extracted data can be used to further study the design of the pneumatic double acting cylinder. It is expected in the future to expand the features of the presented application in order to automate the design process of other related mechanical systems.

  3. Optoisolation circuits nonlinearity applications in engineering : optoisolation nonlinear dynamics and chaos, application in engineering

    CERN Document Server

    Aluf, Ofer

    2012-01-01

    This book describes a new concept in analyzing circuits, which includes optoisolation elements. The analysis is based on nonlinear dynamics and chaos models and shows comprehensive benefits and results. All conceptual optoisolation circuits are innovative and can be broadly implemented in engineering applications. The dynamics of optoisolation circuits provides several ways to use them in a variety of applications covering wide areas. The presentation fills the gap of analytical methods for optoisolation circuits analysis, concrete examples, and geometric examples. The optoisolation circuits analysis is developed systematically, starting with basic optoisolation circuits differential equations and their bifurcations, followed by Fixed points analysis, limit cycles and their bifurcations. Optoisolation circuits can be characterized as Lorenz equations, chaos, iterated maps, period doubling and attractors. This book is aimed at electrical and electronic engineers, students and researchers in physics as well. A ...

  4. The Application of Tissue Engineering Procedures to Repair the Larynx

    Science.gov (United States)

    Ringel, Robert L.; Kahane, Joel C.; Hillsamer, Peter J.; Lee, Annie S.; Badylak, Stephen F.

    2006-01-01

    The field of tissue engineering/regenerative medicine combines the quantitative principles of engineering with the principles of the life sciences toward the goal of reconstituting structurally and functionally normal tissues and organs. There has been relatively little application of tissue engineering efforts toward the organs of speech, voice,…

  5. Sign Detection Theory and Its Applications.

    Science.gov (United States)

    Heine, M. H.

    1984-01-01

    Offers characterization of sign-transmission which is more general than conventional signal-transmission theory. Concepts and terminology, formal description of individual communications process, reconciliation with classical signal-detection theory, applications of sign-detection formalism to information retrieval on MEDLINE database, and a…

  6. Microbial xylanases: engineering, production and industrial applications.

    Science.gov (United States)

    Juturu, Veeresh; Wu, Jin Chuan

    2012-01-01

    and paper industries for a longer time but more and more attention has been paid to using them in producing sugars and other chemicals from lignocelluloses in recent years. Mining new genes from nature, rational engineering of known genes and directed evolution of these genes are required to get tailor-made xylanases for various industrial applications. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Extracellular matrix and tissue engineering applications

    NARCIS (Netherlands)

    Fernandes, H.A.M.; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan

    2009-01-01

    The extracellular matrix is a key component during regeneration and maintenance of tissues and organs, and it therefore plays a critical role in successful tissue engineering as well. Tissue engineers should recognise that engineering technology can be deduced from natural repair processes. Due to

  8. A Model-Based Anomaly Detection Approach for Analyzing Streaming Aircraft Engine Measurement Data

    Science.gov (United States)

    Simon, Donald L.; Rinehart, Aidan Walker

    2015-01-01

    This paper presents a model-based anomaly detection architecture designed for analyzing streaming transient aircraft engine measurement data. The technique calculates and monitors residuals between sensed engine outputs and model predicted outputs for anomaly detection purposes. Pivotal to the performance of this technique is the ability to construct a model that accurately reflects the nominal operating performance of the engine. The dynamic model applied in the architecture is a piecewise linear design comprising steady-state trim points and dynamic state space matrices. A simple curve-fitting technique for updating the model trim point information based on steadystate information extracted from available nominal engine measurement data is presented. Results from the application of the model-based approach for processing actual engine test data are shown. These include both nominal fault-free test case data and seeded fault test case data. The results indicate that the updates applied to improve the model trim point information also improve anomaly detection performance. Recommendations for follow-on enhancements to the technique are also presented and discussed.

  9. Application of value engineering technique in construction project

    International Nuclear Information System (INIS)

    Chen Changbing

    2003-01-01

    The author introduces how to apply the theories and methods of the value engineering in construction project. In the construction of a test device of the thermal hydrodynamic process, the authors have greatly reduced the construction cost and shortened the construction period by using the value engineering analyzing method. The application of value engineering in the project management is innovative. This practice indicates that the value engineering is important in many construction projects

  10. Protocol vulnerability detection based on network traffic analysis and binary reverse engineering.

    Science.gov (United States)

    Wen, Shameng; Meng, Qingkun; Feng, Chao; Tang, Chaojing

    2017-01-01

    Network protocol vulnerability detection plays an important role in many domains, including protocol security analysis, application security, and network intrusion detection. In this study, by analyzing the general fuzzing method of network protocols, we propose a novel approach that combines network traffic analysis with the binary reverse engineering method. For network traffic analysis, the block-based protocol description language is introduced to construct test scripts, while the binary reverse engineering method employs the genetic algorithm with a fitness function designed to focus on code coverage. This combination leads to a substantial improvement in fuzz testing for network protocols. We build a prototype system and use it to test several real-world network protocol implementations. The experimental results show that the proposed approach detects vulnerabilities more efficiently and effectively than general fuzzing methods such as SPIKE.

  11. Protocol vulnerability detection based on network traffic analysis and binary reverse engineering.

    Directory of Open Access Journals (Sweden)

    Shameng Wen

    Full Text Available Network protocol vulnerability detection plays an important role in many domains, including protocol security analysis, application security, and network intrusion detection. In this study, by analyzing the general fuzzing method of network protocols, we propose a novel approach that combines network traffic analysis with the binary reverse engineering method. For network traffic analysis, the block-based protocol description language is introduced to construct test scripts, while the binary reverse engineering method employs the genetic algorithm with a fitness function designed to focus on code coverage. This combination leads to a substantial improvement in fuzz testing for network protocols. We build a prototype system and use it to test several real-world network protocol implementations. The experimental results show that the proposed approach detects vulnerabilities more efficiently and effectively than general fuzzing methods such as SPIKE.

  12. Refresher Course on Tensors and their Applications in Engineering ...

    Indian Academy of Sciences (India)

    Applications in Engineering Sciences. Department of Mechanical Engineering, Indian Institute of Science, Bangalore. December 11-23,2006 sponsored by Indian Academy of Sciences, Bangalore in collaboration with Indian Institute of Science, Bangalore. Applications are invited from University/College teachers, Research ...

  13. Applications of the discrete element method in mechanical engineering

    International Nuclear Information System (INIS)

    Fleissner, Florian; Gaugele, Timo; Eberhard, Peter

    2007-01-01

    Compared to other fields of engineering, in mechanical engineering, the Discrete Element Method (DEM) is not yet a well known method. Nevertheless, there is a variety of simulation problems where the method has obvious advantages due to its meshless nature. For problems where several free bodies can collide and break after having been largely deformed, the DEM is the method of choice. Neighborhood search and collision detection between bodies as well as the separation of large solids into smaller particles are naturally incorporated in the method. The main DEM algorithm consists of a relatively simple loop that basically contains the three substeps contact detection, force computation and integration. However, there exists a large variety of different algorithms to choose the substeps to compose the optimal method for a given problem. In this contribution, we describe the dynamics of particle systems together with appropriate numerical integration schemes and give an overview over different types of particle interactions that can be composed to adapt the method to fit to a given simulation problem. Surface triangulations are used to model complicated, non-convex bodies in contact with particle systems. The capabilities of the method are finally demonstrated by means of application examples

  14. Environmental implications and applications of engineered ...

    Science.gov (United States)

    This review focus on environmental implications and applications of engineered magnetite (Fe3O4) nanoparticles (MNPs) as a single phase or a component of a hybrid nanocomposite that take advantages of their superparamagnetism and high surface area. MNPs are synthesized via co-precipitation, thermal decomposition, hydrothermal process, emulsion, and microbial process. Aggregation/sedimentation and transport of MNPs depend on surface charge of MNPs and geochemical parameters such as pH, ionic strength, and organic matter. MNPs generally have low toxicity to humans and ecosystem. MNPs are used for making excellent anode electrode materials in lithium-ion battery, for constructing biosensors, and for catalyzing a variety of chemical reactions. MNPs are used for air cleanup and carbon sequestration. MNP nanocomposites are made as antimicrobial agent for water disinfection and flocculants for water treatment. Conjugated MNPs are widely used for adsorptive/separative removal of organics, dye, oil, arsenic, Cr(VI), heavy metals, radionuclides, and rare earth elements. MNPs can degrade organic/inorganic contaminants via chemical reduction or oxidation in water, sediment, and soil. Future studies should further explore mechanisms of MNP interactions with other nanomaterials and contaminants, economic and green approaches of MNP synthesis, and field scale demonstration of MNP utilization. Submit to Journal of Hazardous Materials.

  15. System Would Detect Foreign-Object Damage in Turbofan Engine

    Science.gov (United States)

    Torso, James A.; Litt, Jonathan S.

    2006-01-01

    A proposed data-fusion system, to be implemented mostly in software, would further process the digitized and preprocessed outputs of sensors in a turbofan engine to detect foreign-object damage (FOD) [more precisely, damage caused by impingement of such foreign objects as birds, pieces of ice, and runway debris]. The proposed system could help a flight crew to decide what, if any, response is necessary to complete a flight safely, and could aid mechanics in deciding what post-flight maintenance action might be needed. The sensory information to be utilized by the proposed system would consist of (1) the output of an accelerometer in an engine-vibration-monitoring subsystem and (2) features extracted from a gas path analysis. ["Gas path analysis" (GPA) is a term of art that denotes comprehensive analysis of engine performance derived from readings of fuel-flow meters, shaft-speed sensors, temperature sensors, and the like.] The acceleration signal would first be processed by a wavelet-transform-based algorithm, using a wavelet created for the specific purpose of finding abrupt FOD-induced changes in noisy accelerometer signals. Two additional features extracted would be the amplitude of vibration (determined via a single- frequency Fourier transform calculated at the rotational speed of the engine), and the rate of change in amplitude due to an FOD-induced rotor imbalance. This system would utilize two GPA features: the fan efficiency and the rate of change of fan efficiency with time. The selected GPA and vibrational features would be assessed by two fuzzy-logic inference engines, denoted the "Gas Path Expert" and the "Vibration Expert," respectively (see Figure 1). Each of these inference engines would generate a "possibility" distribution for occurrence of an FOD event: Each inference engine would assign, to its input information, degrees of membership, which would subsequently be transformed into basic probability assignments for the gas path and vibration

  16. VoIP attacks detection engine based on neural network

    Science.gov (United States)

    Safarik, Jakub; Slachta, Jiri

    2015-05-01

    The security is crucial for any system nowadays, especially communications. One of the most successful protocols in the field of communication over IP networks is Session Initiation Protocol. It is an open-source project used by different kinds of applications, both open-source and proprietary. High penetration and text-based principle made SIP number one target in IP telephony infrastructure, so security of SIP server is essential. To keep up with hackers and to detect potential malicious attacks, security administrator needs to monitor and evaluate SIP traffic in the network. But monitoring and following evaluation could easily overwhelm the security administrator in networks, typically in networks with a number of SIP servers, users and logically or geographically separated networks. The proposed solution lies in automatic attack detection systems. The article covers detection of VoIP attacks through a distributed network of nodes. Then the gathered data analyze aggregation server with artificial neural network. Artificial neural network means multilayer perceptron network trained with a set of collected attacks. Attack data could also be preprocessed and verified with a self-organizing map. The source data is detected by distributed network of detection nodes. Each node contains a honeypot application and traffic monitoring mechanism. Aggregation of data from each node creates an input for neural networks. The automatic classification on a centralized server with low false positive detection reduce the cost of attack detection resources. The detection system uses modular design for easy deployment in final infrastructure. The centralized server collects and process detected traffic. It also maintains all detection nodes.

  17. Recent advances in electrical engineering and control applications

    CERN Document Server

    Bououden, Sofiane; Zelinka, Ivan

    2017-01-01

    This book of proceedings includes papers presenting the state of art in electrical engineering and control theory as well as their applications. The topics focus on classical as well as modern methods for modeling, control, identification and simulation of complex systems with applications in science and engineering. The papers were selected from the hottest topic areas, such as control and systems engineering, renewable energy, faults diagnosis—faults tolerant control, large-scale systems, fractional order systems, unconventional algorithms in control engineering, signals and communications. The control and design of complex systems dynamics, analysis and modeling of its behavior and structure is vitally important in engineering, economics and in science generally science today. Examples of such systems can be seen in the world around us and are a part of our everyday life. Application of modern methods for control, electronics, signal processing and more can be found in our mobile phones, car engines, hom...

  18. Applications of sliding mode control in science and engineering

    CERN Document Server

    Lien, Chang-Hua

    2017-01-01

    Gathering 20 chapters contributed by respected experts, this book reports on the latest advances in and applications of sliding mode control in science and engineering. The respective chapters address applications of sliding mode control in the broad areas of chaos theory, robotics, electrical engineering, physics, chemical engineering, memristors, mechanical engineering, environmental engineering, finance, and biology. Special emphasis has been given to papers that offer practical solutions, and which examine design and modeling involving new types of sliding mode control such as higher order sliding mode control, terminal sliding mode control, super-twisting sliding mode control, and integral sliding mode control. This book serves as a unique reference guide to sliding mode control and its recent applications for graduate students and researchers with a basic knowledge of electrical and control systems engineering.

  19. International conference on Information Engineering and Applications (IEA) 2012

    CERN Document Server

    2013-01-01

    Information engineering and applications is the field of study concerned with constructing information computing, intelligent systems, mathematical models, numerical solution techniques, and using computers and other electronic devices to analyze and solve natural scientific, social scientific and engineering problems.   Information engineering is an important underpinning for techniques used in information and computational science and there are many unresolved problems worth studying. The Proceedings of the 2nd International Conference on Information Engineering and Applications (IEA 2012), which was held in Chongqing, China, from October 26-28, 2012, discusses the most innovative research and developments including technical challenges and social, legal, political, and economic issues.   A forum for engineers and scientists in academia, industry, and government, the Proceedings of the 2nd International Conference on Information Engineering and Applications presents ideas, results, works in progress, and ...

  20. Application of Statistics in Engineering Technology Programs

    Science.gov (United States)

    Zhan, Wei; Fink, Rainer; Fang, Alex

    2010-01-01

    Statistics is a critical tool for robustness analysis, measurement system error analysis, test data analysis, probabilistic risk assessment, and many other fields in the engineering world. Traditionally, however, statistics is not extensively used in undergraduate engineering technology (ET) programs, resulting in a major disconnect from industry…

  1. Teaching learning based optimization algorithm and its engineering applications

    CERN Document Server

    Rao, R Venkata

    2016-01-01

    Describing a new optimization algorithm, the “Teaching-Learning-Based Optimization (TLBO),” in a clear and lucid style, this book maximizes reader insights into how the TLBO algorithm can be used to solve continuous and discrete optimization problems involving single or multiple objectives. As the algorithm operates on the principle of teaching and learning, where teachers influence the quality of learners’ results, the elitist version of TLBO algorithm (ETLBO) is described along with applications of the TLBO algorithm in the fields of electrical engineering, mechanical design, thermal engineering, manufacturing engineering, civil engineering, structural engineering, computer engineering, electronics engineering, physics and biotechnology. The book offers a valuable resource for scientists, engineers and practitioners involved in the development and usage of advanced optimization algorithms.

  2. The Application of Quantum Energy Saver on Engine

    Directory of Open Access Journals (Sweden)

    Fang Xiong

    2016-01-01

    Full Text Available In order to reduce diesel fuel consumption, this paper conducts the research in view of a new type of quantum energy saving device, and then produce the sample and applied on automobile engine, Detect fuel use of an automobile by automobile fuel saving technology as-sessment methods from the department of transportation. Compare the changes of fuel use be-fore and after installation of quantum energy saving device on the same car, and give the feed-back of energy saving capability. The result shows, after installed quantum energy saver, both fuel consumption and the smoke of tail gas has decreased. The analysis and application of this paper carry out the conclusion that the quantum energy saver can play an important role in en-ergy saving and emission reduction, and provide a reference for other related research.

  3. Engineering nanomaterials-based biosensors for food safety detection.

    Science.gov (United States)

    Lv, Man; Liu, Yang; Geng, Jinhui; Kou, Xiaohong; Xin, Zhihong; Yang, Dayong

    2018-05-30

    Food safety always remains a grand global challenge to human health, especially in developing countries. To solve food safety pertained problems, numerous strategies have been developed to detect biological and chemical contaminants in food. Among these approaches, nanomaterials-based biosensors provide opportunity to realize rapid, sensitive, efficient and portable detection, overcoming the restrictions and limitations of traditional methods such as complicated sample pretreatment, long detection time, and relying on expensive instruments and well-trained personnel. In this review article, we provide a cross-disciplinary perspective to review the progress of nanomaterials-based biosensors for the detection of food contaminants. The review article is organized by the category of food contaminants including pathogens/toxins, heavy metals, pesticides, veterinary drugs and illegal additives. In each category of food contaminant, the biosensing strategies are summarized including optical, colorimetric, fluorescent, electrochemical, and immune- biosensors; the relevant analytes, nanomaterials and biosensors are analyzed comprehensively. Future perspectives and challenges are also discussed briefly. We envision that our review could bridge the gap between the fields of food science and nanotechnology, providing implications for the scientists or engineers in both areas to collaborate and promote the development of nanomaterials-based biosensors for food safety detection. Copyright © 2018 Elsevier B.V. All rights reserved.

  4. Video motion detection for physical security applications

    International Nuclear Information System (INIS)

    Matter, J.C.

    1990-01-01

    Physical security specialists have been attracted to the concept of video motion detection for several years. Claimed potential advantages included additional benefit from existing video surveillance systems, automatic detection, improved performance compared to human observers, and cost-effectiveness. In recent years, significant advances in image-processing dedicated hardware and image analysis algorithms and software have accelerated the successful application of video motion detection systems to a variety of physical security applications. Early video motion detectors (VMDs) were useful for interior applications of volumetric sensing. Success depended on having a relatively well-controlled environment. Attempts to use these systems outdoors frequently resulted in an unacceptable number of nuisance alarms. Currently, Sandia National Laboratories (SNL) is developing several advanced systems that employ image-processing techniques for a broader set of safeguards and security applications. The Target Cueing and Tracking System (TCATS), the Video Imaging System for Detection, Tracking, and Assessment (VISDTA), the Linear Infrared Scanning Array (LISA); the Mobile Intrusion Detection and Assessment System (MIDAS), and the Visual Artificially Intelligent Surveillance (VAIS) systems are described briefly

  5. Controlling LPG temperature for SI engine applications

    International Nuclear Information System (INIS)

    Ceviz, Mehmet Akif; Kaleli, Alirıza; Güner, Erdoğan

    2015-01-01

    In this study, the effects of the LPG temperature on the engine performance and the exhaust emission characteristics have been investigated experimentally on an SI engine. In conventional injection systems, the LPG temperature increases excessively during the phase change in pressure regulator, and reduces the engine volumetric efficiency. According to the test results, engine performance and NO emission characteristics can be improved by controlling the LPG temperature before injecting to the engine intake manifold. A new control system taking into account the results of the study has been developed and tested. In order to control the LPG temperature, the coolant flow rate in pressure regulator circuit was arranged by using a control valve activated by a PID controller unit. Results of the study showed that the engine brake power loss can be increased by about 1.85% and NO emissions can be decreased by about 2% as compared to the operation with the original LPG injection system. - Highlights: • Effects of the LPG temperature have been examined. • Engine performance characteristics and exhaust emissions have been studied. • Results reveal that the LPG temperature should be kept in a range. • A prototype LPG temperature control system has been successfully developed

  6. Protein engineering and its applications in food industry.

    Science.gov (United States)

    Kapoor, Swati; Rafiq, Aasima; Sharma, Savita

    2017-07-24

    Protein engineering is a young discipline that has been branched out from the field of genetic engineering. Protein engineering is based on the available knowledge about the proteins structure/function(s), tools/instruments, software, bioinformatics database, available cloned gene, knowledge about available protein, vectors, recombinant strains and other materials that could lead to change in the protein backbone. Protein produced properly from genetic engineering process means a protein that is able to fold correctly and to do particular function(s) efficiently even after being subjected to engineering practices. Protein is modified through its gene or chemically. However, modification of protein through gene is easier. There is no specific limitation of Protein Engineering tools; any technique that can lead to change the protein constituent of amino acid and result in the modification of protein structure/function is in the frame of Protein Engineering. Meanwhile, there are some common tools used to reach a specific target. More active industrial and pharmaceutical based proteins have been invented by the field of Protein Engineering to introduce new function as well as to change its interaction with surrounding environment. A variety of protein engineering applications have been reported in the literature. These applications range from biocatalysis for food and industry to environmental, medical and nanobiotechnology applications. Successful combinations of various protein engineering methods had led to successful results in food industries and have created a scope to maintain the quality of finished product after processing.

  7. Reliability of ceramics for heat engine applications

    Science.gov (United States)

    1980-01-01

    The advantages and disadvantages associated with the use of monolithic ceramics in heat engines are discussed. The principle gaps in the state of understanding of ceramic material, failure origins, nondestructive tests as well as life prediction are included.

  8. Aerospike Nozzle for Rotating Detonation Engine Application

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal presents a graduate MS research thesis on improving the efficiency of rotating detonation engines by using aerospike nozzle technologies. A rotating...

  9. Introduction to tissue engineering applications and challenges

    CERN Document Server

    Birla, Ravi

    2014-01-01

    Covering a progressive medical field, Tissue Engineering describes the innovative process of regenerating human cells to restore or establish normal function in defective organs. As pioneering individuals look ahead to the possibility of generating entire organ systems, students may turn to this textbook for a comprehensive understanding and preparation for the future of regenerative medicine. This book explains chemical stimulations, the bioengineering of specific organs, and treatment plans for chronic diseases. It is a must-read for tissue engineering students and practitioners.

  10. New spam-detection engine for CERN mailboxes

    CERN Multimedia

    IT Department

    2008-01-01

    The flow of spam (unsolicited e-mail) targetting CERN mailboxes is constantly increasing: 96% of the 2.5 million mails received daily at CERN consist in successfully filtered spam, but spammers get smarter and detecting spam is becoming ever more difficult. In order to address this evolution, a new spam-detection software engine will progressively be deployed starting from 15 April 2008. It will not affect how CERN users currently deal with spam: the spam configuration page, the ‘CERN Spam’ folder and the Outlook ‘report spam’ button will continue to work exactly as before. Because spam detection is based on probabilities, some legitimate messages can sometimes be incorrectly detected as spam. We invite all users of CERN mailboxes to regularly check their ‘CERN spam’ folder for such messages. To prevent incorrect filtering of legitimate messages, it is possible to set up a whitelist (list of trusted e-mail addresses that bypass the spam filter) and adjust the spa...

  11. New spam-detection engine for CERN mailboxes

    CERN Multimedia

    The flow of spam (unsolicited e-mail) targetting CERN mailboxes is constantly increasing: 96% of the 2.5 million mails received daily at CERN consist in successfully filtered spam, but spammers get smarter and detecting spam is becoming ever more difficult. In order to address this evolution, a new spam-detection software engine will progressively be deployed starting from 15 April 2008. It will not affect how CERN users currently deal with spam: the spam configuration page, the 'CERN Spam' folder and the Outlook 'report spam' button will continue to work exactly as before. Because spam detection is based on probabilities, some legitimate messages can sometimes be incorrectly detected as spam. We invite all users of CERN mailboxes to regularly check their 'CERN spam' folder for such messages. To prevent incorrect filtering of legitimate messages, it is possible to set up a whitelist (list of trusted e-mail addresses that bypass the spam filter) and adjust the spam filtering level from the CERN mailbox confi...

  12. The application of human engineering in control room of HFETR

    International Nuclear Information System (INIS)

    Yang Shuchun; Shan Songlin

    2003-01-01

    The human-machine system for improving the working environment in the control room of HFETR is described. The reliability of the equipment, instruments and operation by human engineering is increased. The relations between human engineering and lowering human failure in HFETR are also discussed. It is concluded that the further application of human engineering can increase interaction of the human and machine in the control room and provide assurances for the safe and reliable operation of reactor. (authors)

  13. The application of human engineering in control room of HFETR

    Energy Technology Data Exchange (ETDEWEB)

    Shuchun, Yang; Songlin, Shan [Nuclear Power Inst. of China, Chengdu (China)

    2003-07-01

    The human-machine system for improving the working environment in the control room of HFETR is described. The reliability of the equipment, instruments and operation by human engineering is increased. The relations between human engineering and lowering human failure in HFETR are also discussed. It is concluded that the further application of human engineering can increase interaction of the human and machine in the control room and provide assurances for the safe and reliable operation of reactor. (authors)

  14. Stirling engine alternatives for the terrestrial solar application

    Science.gov (United States)

    Stearns, J.

    1985-01-01

    The first phase of the present study of Stirling engine alternatives for solar thermal-electric generation has been completed. Development risk levels are considered to be high for all engines evaluated. Free-piston type and Ringbom-type Stirling engine-alternators are not yet developed for the 25 to 50-kW electrical power range, although smaller machines have demonstrated the inherent robustness of the machines. Kinematic-type Stirling engines are presently achieving a 3500 hr lifetime or longer on critical components, and lifetime must still be further extended for the solar application. Operational and technical characteristics of all types of Stirling engines have been reviewed with engine developers. Technical work of merit in progress in each engine development organization should be recognized and supported in an appropriate manner.

  15. Towards evolution-guided microbial engineering - tools development and applications

    DEFF Research Database (Denmark)

    Genee, Hans Jasper

    is thedevelopment of highly robust biosensor-based synthetic selection systemsthat enable high-throughput functional interrogation of complexphenotypic libraries. Using the model organism Escherichia coli as a host, Ideploy these systems to i) perform metagenome wide sequenceindependentidentification of novel...... for microbial engineering anddemonstrates direct applications to gene discovery, protein engineering andcell factory development....

  16. Systematic Applications of Metabolomics in Metabolic Engineering

    Directory of Open Access Journals (Sweden)

    Robert A. Dromms

    2012-12-01

    Full Text Available The goals of metabolic engineering are well-served by the biological information provided by metabolomics: information on how the cell is currently using its biochemical resources is perhaps one of the best ways to inform strategies to engineer a cell to produce a target compound. Using the analysis of extracellular or intracellular levels of the target compound (or a few closely related molecules to drive metabolic engineering is quite common. However, there is surprisingly little systematic use of metabolomics datasets, which simultaneously measure hundreds of metabolites rather than just a few, for that same purpose. Here, we review the most common systematic approaches to integrating metabolite data with metabolic engineering, with emphasis on existing efforts to use whole-metabolome datasets. We then review some of the most common approaches for computational modeling of cell-wide metabolism, including constraint-based models, and discuss current computational approaches that explicitly use metabolomics data. We conclude with discussion of the broader potential of computational approaches that systematically use metabolomics data to drive metabolic engineering.

  17. Institute for Computer Applications in Science and Engineering (ICASE)

    Science.gov (United States)

    1984-01-01

    Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis and computer science during the period April 1, 1983 through September 30, 1983 is summarized.

  18. Medical Engineering and Microneurosurgery: Application and Future.

    Science.gov (United States)

    Morita, Akio; Sora, Shigeo; Nakatomi, Hirofumi; Harada, Kanako; Sugita, Naohiko; Saito, Nobuhito; Mitsuishi, Mamoru

    2016-10-15

    Robotics and medical engineering can convert traditional surgery into digital and scientific procedures. Here, we describe our work to develop microsurgical robotic systems and apply engineering technology to assess microsurgical skills. With the collaboration of neurosurgeons and an engineering team, we have developed two types of microsurgical robotic systems. The first, the deep surgical systems, enable delicate surgical procedures such as vessel suturing in a deep and narrow space. The second type allows for super-fine surgical procedures such as anastomosing artificial vessels of 0.3 mm in diameter. Both systems are constructed with master and slave manipulator robots connected to local area networks. Robotic systems allowed for secure and accurate procedures in a deep surgical field. In cadaveric models, these systems showed a good potential of being useful in actual human surgeries, but mechanical refinements in thickness and durability are necessary for them to be established as clinical systems. The super-fine robotic system made the very intricate surgery possible and will be applied in clinical trials. Another trial included the digitization of surgical technique and scientific analysis of surgical skills. Robotic and human hand motions were analyzed in numerical fashion as we tried to define surgical skillfulness in a digital format. Engineered skill assessment is also feasible and should be useful for microsurgical training. Robotics and medical engineering should bring science into the surgical field and training of surgeons. Active collaboration between medical and engineering teams and academic and industry groups is mandatory to establish such medical systems to improve patient care.

  19. International Conference on Soft Computing Techniques and Engineering Application

    CERN Document Server

    Li, Xiaolong

    2014-01-01

    The main objective of ICSCTEA 2013 is to provide a platform for researchers, engineers and academicians from all over the world to present their research results and development activities in soft computing techniques and engineering application. This conference provides opportunities for them to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration.

  20. Key applications of plant metabolic engineering.

    Directory of Open Access Journals (Sweden)

    Warren Lau

    2014-06-01

    Full Text Available Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy their own nitrogen requirement, so reducing or eliminating the need for nitrogen fertilizer; enhancing the nutrient content of crop plants; engineering biofuel feed stocks that harbor easy-to-access fermentable saccharides by incorporating self-destructing lignin; and increasing photosynthetic efficiency. We also look to the future at emerging areas of research in this field.

  1. A Software Application to Detect Dental Color

    Directory of Open Access Journals (Sweden)

    Dan SÎMPĂLEAN

    2015-09-01

    Full Text Available Choosing dental color for missing teeth or tooth reconstruction is an important step and it usually raises difficulties for dentists due to a significant amount of subjective factors that can influence the color selection. Dental reconstruction presumes the combination between dentistry and chromatics, thus implying important challenges. Purpose: The aim of this study was to develop and implement a software application for detecting dental color to come to the aid of dentists and largely to remove the inherent subjectiveness of the human vision. Basic Methods: The implemented application was named Color Detection and the application’s source code is written using the C++ language. During application development, for creating the GUI (graphical user interface the wxWidgets 2.8 library it was used. Results: The application displays the average color of the selected area of interest, the reference color from the key collection existent in the program and also the degree of similarity between the original (the selected area of interest and the nearest reference key. This degree of similarity is expressed as a percentage. Conclusions: The Color Detection Program, by eliminating the subjectivity inherent to human sight, can help the dentist to select an appropriate dental color with precision.

  2. Fundamentals of reliability engineering applications in multistage interconnection networks

    CERN Document Server

    Gunawan, Indra

    2014-01-01

    This book presents fundamentals of reliability engineering with its applications in evaluating reliability of multistage interconnection networks. In the first part of the book, it introduces the concept of reliability engineering, elements of probability theory, probability distributions, availability and data analysis.  The second part of the book provides an overview of parallel/distributed computing, network design considerations, and more.  The book covers a comprehensive reliability engineering methods and its practical aspects in the interconnection network systems. Students, engineers, researchers, managers will find this book as a valuable reference source.

  3. Applications of Statistics and Probability in Civil Engineering

    DEFF Research Database (Denmark)

    Faber, Michael Havbro

    contains the proceedings of the 11th International Conference on Applications of Statistics and Probability in Civil Engineering (ICASP11, Zürich, Switzerland, 1-4 August 2011). The book focuses not only on the more traditional technical issues, but also emphasizes the societal context...... and reliability in engineering; to professionals and engineers, including insurance and consulting companies working with natural hazards, design, operation and maintenance of civil engineering and industrial facilities; and to decision makers and professionals in the public sector, including nongovernmental...

  4. Application of industrial CT in reverse engineering technology

    International Nuclear Information System (INIS)

    Fang Liyong; Li Hui; Bai Jinping; Li Bailin

    2013-01-01

    The basic principle and basic steps of reverse engineering technology based on industrial CT are described. The recent research progresses and situation at home and abroad of reverse engineering technology based on industrial CT image are respectively described, analyzed and summarized from two routes which are surface segmentation and volume segmentation. An example of conch is used to exhibit the results from the two routes in reverse engineering technology based on industrial CT image. Finally, some difficulties in application and the future developments of reverse engineering technology based on industrial CT are prospected. (authors)

  5. Engineering applications of pneumatics and hydraulics

    CERN Document Server

    Turner, Ian C

    2014-01-01

    Assuming only the most basic knowledge of the physics of fluids, this book aims to equip the reader with a sound understanding of fluid power systems and their uses in practical engineering. In line with the strongly practical bias of the book, maintenance and trouble-shooting are covered, with particular emphasis on safety systems and regulations.

  6. Ramgen Power Systems for Military Engine Applications

    Science.gov (United States)

    2007-05-01

    never been realized or consid- ered. In addition, the reduced footprint and the potential for vertical ver- sus horizontal engine mounting will...Ramgen CO2 compressor to conventional machines. Intergrally Inline Geared Process Turbo Turbo Ramgen lbm/h 150000 150000 150000 icfm 21411 21411 21411

  7. Confocal Raman Microscopy; applications in tissue engineering

    NARCIS (Netherlands)

    van Apeldoorn, Aart A.

    2005-01-01

    This dissertation describes the use of confocal Raman microscopy and spectroscopy in the field of tissue engineering. Moreover, it describes the combination of two already existing technologies, namely scanning electron microscopy and confocal Raman spectroscopy in one apparatus for the enhancement

  8. Advances in Industrial Engineering Applications and Pratice

    DEFF Research Database (Denmark)

    Sørensen, Torben

    1997-01-01

    are known as Computer Integrated Manufacturing and Engineering (CIME) systems. The basic concept in CIME is to share and reuse information between the different computer based subsystems. Consequently, for the integration purposes, the CIME systems are highly dependent on reliable product model interfaces...

  9. The application of reaction engineering to biocatalysis

    DEFF Research Database (Denmark)

    Ringborg, Rolf Hoffmeyer; Woodley, John

    2016-01-01

    outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes....

  10. SDM applications to machine tools and engines

    Indian Academy of Sciences (India)

    Abstract. The method of structural dynamic optimization is applied here to ... variations of mass, stiffness and/or damping, lumped on a limited number of positions of the path. ... The direct path is through the cylinder head and the engine block.

  11. Statistics and probability with applications for engineers and scientists

    CERN Document Server

    Gupta, Bhisham C

    2013-01-01

    Introducing the tools of statistics and probability from the ground up An understanding of statistical tools is essential for engineers and scientists who often need to deal with data analysis over the course of their work. Statistics and Probability with Applications for Engineers and Scientists walks readers through a wide range of popular statistical techniques, explaining step-by-step how to generate, analyze, and interpret data for diverse applications in engineering and the natural sciences. Unique among books of this kind, Statistics and Prob

  12. Advances in Computer Science, Engineering & Applications : Proceedings of the Second International Conference on Computer Science, Engineering & Applications

    CERN Document Server

    Zizka, Jan; Nagamalai, Dhinaharan

    2012-01-01

    The International conference series on Computer Science, Engineering & Applications (ICCSEA) aims to bring together researchers and practitioners from academia and industry to focus on understanding computer science, engineering and applications and to establish new collaborations in these areas. The Second International Conference on Computer Science, Engineering & Applications (ICCSEA-2012), held in Delhi, India, during May 25-27, 2012 attracted many local and international delegates, presenting a balanced mixture of  intellect and research both from the East and from the West. Upon a strenuous peer-review process the best submissions were selected leading to an exciting, rich and a high quality technical conference program, which featured high-impact presentations in the latest developments of various areas of computer science, engineering and applications research.  

  13. Advances in Computer Science, Engineering & Applications : Proceedings of the Second International Conference on Computer Science, Engineering & Applications

    CERN Document Server

    Zizka, Jan; Nagamalai, Dhinaharan

    2012-01-01

    The International conference series on Computer Science, Engineering & Applications (ICCSEA) aims to bring together researchers and practitioners from academia and industry to focus on understanding computer science, engineering and applications and to establish new collaborations in these areas. The Second International Conference on Computer Science, Engineering & Applications (ICCSEA-2012), held in Delhi, India, during May 25-27, 2012 attracted many local and international delegates, presenting a balanced mixture of  intellect and research both from the East and from the West. Upon a strenuous peer-review process the best submissions were selected leading to an exciting, rich and a high quality technical conference program, which featured high-impact presentations in the latest developments of various areas of computer science, engineering and applications research.

  14. Cosmic Muon Detection for Geophysical Applications

    Directory of Open Access Journals (Sweden)

    László Oláh

    2013-01-01

    Full Text Available A portable cosmic muon detector has been developed for environmental, geophysical, or industrial applications. The device is a tracking detector based on the Close Cathode Chamber, an MWPC-like technology, allowing operation in natural underground caves or artificial tunnels, far from laboratory conditions. The compact, low power consumption system with sensitive surface of 0.1 m2 measures the angular distribution of cosmic muons with a resolution of 10 mrad, allowing for a detailed mapping of the rock thickness above the muon detector. Demonstration of applicability of the muon telescope (REGARD Muontomograph for civil engineering and measurements in artificial underground tunnels or caverns are presented.

  15. Android Application Protection against Static Reverse Engineering based on Multidexing

    Directory of Open Access Journals (Sweden)

    Nak Young Kim

    2016-11-01

    Full Text Available DEX files are executable files of Android applications. Since DEX files are in the format of Java bytecodes, their Java source codes can be easily obtained using static reverse engineering tools. This results in numerous Android application thefts. There are some tools (e.g. bangcle, ijiami, liapp that protect Android applications against static reverse engineering utilizing dynamic code loading. These tools usually encrypt classes.dex in an APK file. When the application is launched, the encrypted classes.dex file is decrypted and dynamically loaded. However, these tools fail to protect multidex APKs, which include more than one DEX files (classes2.dex, classes3.dex, ... to accommodate large-sized execution codes. In this paper, we propose a technique that protects multidex Android applications against static reverse engineering. The technique can encrypt/decrypt multiple DEX files in APK files and dynamically load them. The experimental results show that the proposed technique can effiectively protect multidex APKs.

  16. Parallel science and engineering applications the Charm++ approach

    CERN Document Server

    Kale, Laxmikant V

    2016-01-01

    Developed in the context of science and engineering applications, with each abstraction motivated by and further honed by specific application needs, Charm++ is a production-quality system that runs on almost all parallel computers available. Parallel Science and Engineering Applications: The Charm++ Approach surveys a diverse and scalable collection of science and engineering applications, most of which are used regularly on supercomputers by scientists to further their research. After a brief introduction to Charm++, the book presents several parallel CSE codes written in the Charm++ model, along with their underlying scientific and numerical formulations, explaining their parallelization strategies and parallel performance. These chapters demonstrate the versatility of Charm++ and its utility for a wide variety of applications, including molecular dynamics, cosmology, quantum chemistry, fracture simulations, agent-based simulations, and weather modeling. The book is intended for a wide audience of people i...

  17. Advances in polymeric systems for tissue engineering and biomedical applications.

    Science.gov (United States)

    Ravichandran, Rajeswari; Sundarrajan, Subramanian; Venugopal, Jayarama Reddy; Mukherjee, Shayanti; Ramakrishna, Seeram

    2012-03-01

    The characteristics of tissue engineered scaffolds are major concerns in the quest to fabricate ideal scaffolds for tissue engineering applications. The polymer scaffolds employed for tissue engineering applications should possess multifunctional properties such as biocompatibility, biodegradability and favorable mechanical properties as it comes in direct contact with the body fluids in vivo. Additionally, the polymer system should also possess biomimetic architecture and should support stem cell adhesion, proliferation and differentiation. As the progress in polymer technology continues, polymeric biomaterials have taken characteristics more closely related to that desired for tissue engineering and clinical needs. Stimuli responsive polymers also termed as smart biomaterials respond to stimuli such as pH, temperature, enzyme, antigen, glucose and electrical stimuli that are inherently present in living systems. This review highlights the exciting advancements in these polymeric systems that relate to biological and tissue engineering applications. Additionally, several aspects of technology namely scaffold fabrication methods and surface modifications to confer biological functionality to the polymers have also been discussed. The ultimate objective is to emphasize on these underutilized adaptive behaviors of the polymers so that novel applications and new generations of smart polymeric materials can be realized for biomedical and tissue engineering applications. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Uprated OMS engine status and future applications

    Science.gov (United States)

    Boyd, W. C.; Brasher, W. L.

    1986-01-01

    The baseline Orbital Maneuvering Engine (OME) of the Space Shuttle has the potential for significant performance uprating, leading to increased Shuttle performance capability. The approach to uprating that is being pursued at the NASA Lyndon B. Johnson Space Center is the use of a gas generator-driven turbopump to increase OME operating pressure. A higher pressure engine can have a greater nozzle expansion ratio in the same envelope and at the same thrust level, giving increased engine Isp. The results of trade studies and analyses that have led to the preferred uprated OME configuration are described. The significant accomplishments of a pre-development component demonstration program are also presented, including descriptions of test hardware and discussion of test results. It is shown that testing to date confirms the capability of the preferred uprated OME configuration to meet or exceed performance and life requirements. Potential future activities leading up to a full-scale development program are described, and the capability for the uprated OME to be used in future storable propellant upper stages is discussed.

  19. NASA Applications and Lessons Learned in Reliability Engineering

    Science.gov (United States)

    Safie, Fayssal M.; Fuller, Raymond P.

    2011-01-01

    Since the Shuttle Challenger accident in 1986, communities across NASA have been developing and extensively using quantitative reliability and risk assessment methods in their decision making process. This paper discusses several reliability engineering applications that NASA has used over the year to support the design, development, and operation of critical space flight hardware. Specifically, the paper discusses several reliability engineering applications used by NASA in areas such as risk management, inspection policies, components upgrades, reliability growth, integrated failure analysis, and physics based probabilistic engineering analysis. In each of these areas, the paper provides a brief discussion of a case study to demonstrate the value added and the criticality of reliability engineering in supporting NASA project and program decisions to fly safely. Examples of these case studies discussed are reliability based life limit extension of Shuttle Space Main Engine (SSME) hardware, Reliability based inspection policies for Auxiliary Power Unit (APU) turbine disc, probabilistic structural engineering analysis for reliability prediction of the SSME alternate turbo-pump development, impact of ET foam reliability on the Space Shuttle System risk, and reliability based Space Shuttle upgrade for safety. Special attention is given in this paper to the physics based probabilistic engineering analysis applications and their critical role in evaluating the reliability of NASA development hardware including their potential use in a research and technology development environment.

  20. Connecting NASA science and engineering with earth science applications

    Science.gov (United States)

    The National Research Council (NRC) recently highlighted the dual role of NASA to support both science and applications in planning Earth observations. This Editorial reports the efforts of the NASA Soil Moisture Active Passive (SMAP) mission to integrate applications with science and engineering i...

  1. Engineering artificial machines from designable DNA materials for biomedical applications.

    Science.gov (United States)

    Qi, Hao; Huang, Guoyou; Han, Yulong; Zhang, Xiaohui; Li, Yuhui; Pingguan-Murphy, Belinda; Lu, Tian Jian; Xu, Feng; Wang, Lin

    2015-06-01

    Deoxyribonucleic acid (DNA) emerges as building bricks for the fabrication of nanostructure with complete artificial architecture and geometry. The amazing ability of DNA in building two- and three-dimensional structures raises the possibility of developing smart nanomachines with versatile controllability for various applications. Here, we overviewed the recent progresses in engineering DNA machines for specific bioengineering and biomedical applications.

  2. CVD diamond for nuclear detection applications

    CERN Document Server

    Bergonzo, P; Tromson, D; Mer, C; Guizard, B; Marshall, R D; Foulon, F

    2002-01-01

    Chemically vapour deposited (CVD) diamond is a remarkable material for the fabrication of radiation detectors. In fact, there exist several applications where other standard semiconductor detectors do not fulfil the specific requirements imposed by corrosive, hot and/or high radiation dose environments. The improvement of the electronic properties of CVD diamond has been under intensive investigations and led to the development of a few applications that are addressing specific industrial needs. Here, we report on CVD diamond-based detector developments and we describe how this material, even though of a polycrystalline nature, is readily of great interest for applications in the nuclear industry as well as for physics experiments. Improvements in the material synthesis as well as on device fabrication especially concern the synthesis of films that do not exhibit space charge build up effects which are often encountered in CVD diamond materials and that are highly detrimental for detection devices. On a pre-i...

  3. Engineering application of anaerobic ammonium oxidation process in wastewater treatment.

    Science.gov (United States)

    Mao, Nianjia; Ren, Hongqiang; Geng, Jinju; Ding, Lili; Xu, Ke

    2017-08-01

    Anaerobic ammonium oxidation (Anammox), a promising biological nitrogen removal process, has been verified as an efficient, sustainable and cost-effective alternative to conventional nitrification and denitrification processes. To date, more than 110 full-scale anammox plants have been installed and are in operation, treating industrial NH 4 + -rich wastewater worldwide, and anammox-based technologies are flourishing. This review the current state of the art for engineering applications of the anammox process, including various anammox-based technologies, reactor selection and attempts to apply it at different wastewater plants. Process control and implementation for stable performance are discussed as well as some remaining issues concerning engineering application are exposed, including the start-up period, process disturbances, greenhouse gas emissions and especially mainstream anammox applications. Finally, further development of the anammox engineering application is proposed in this review.

  4. Microwave RF antennas and circuits nonlinearity applications in engineering

    CERN Document Server

    Aluf, Ofer

    2017-01-01

    This book describes a new concept for analyzing RF/microwave circuits, which includes RF/microwave antennas. The book is unique in its emphasis on practical and innovative microwave RF engineering applications. The analysis is based on nonlinear dynamics and chaos models and shows comprehensive benefits and results. All conceptual RF microwave circuits and antennas are innovative and can be broadly implemented in engineering applications. Given the dynamics of RF microwave circuits and antennas, they are suitable for use in a broad range of applications. The book presents analytical methods for microwave RF antennas and circuit analysis, concrete examples, and geometric examples. The analysis is developed systematically, starting with basic differential equations and their bifurcations, and subsequently moving on to fixed point analysis, limit cycles and their bifurcations. Engineering applications include microwave RF circuits and antennas in a variety of topological structures, RFID ICs and antennas, micros...

  5. Printed strain sensors for early damage detection in engineering structures

    Science.gov (United States)

    Zymelka, Daniel; Yamashita, Takahiro; Takamatsu, Seiichi; Itoh, Toshihiro; Kobayashi, Takeshi

    2018-05-01

    In this paper, we demonstrate the analysis of strain measurements recorded using a screen-printed sensors array bonded to a metal plate and subjected to high strains. The analysis was intended to evaluate the capabilities of the printed strain sensors to detect abnormal strain distribution before actual defects (cracks) in the analyzed structures appear. The results demonstrate that the developed device can accurately localize the enhanced strains at the very early stage of crack formation. The promising performance and low fabrication cost confirm the potential suitability of the printed strain sensors for applications within the framework of structural health monitoring (SHM).

  6. Aircraft applications of fault detection and isolation techniques

    Science.gov (United States)

    Marcos Esteban, Andres

    In this thesis the problems of fault detection & isolation and fault tolerant systems are studied from the perspective of LTI frequency-domain, model-based techniques. Emphasis is placed on the applicability of these LTI techniques to nonlinear models, especially to aerospace systems. Two applications of Hinfinity LTI fault diagnosis are given using an open-loop (no controller) design approach: one for the longitudinal motion of a Boeing 747-100/200 aircraft, the other for a turbofan jet engine. An algorithm formalizing a robust identification approach based on model validation ideas is also given and applied to the previous jet engine. A general linear fractional transformation formulation is given in terms of the Youla and Dual Youla parameterizations for the integrated (control and diagnosis filter) approach. This formulation provides better insight into the trade-off between the control and the diagnosis objectives. It also provides the basic groundwork towards the development of nested schemes for the integrated approach. These nested structures allow iterative improvements on the control/filter Youla parameters based on successive identification of the system uncertainty (as given by the Dual Youla parameter). The thesis concludes with an application of Hinfinity LTI techniques to the integrated design for the longitudinal motion of the previous Boeing 747-100/200 model.

  7. Application of local area network technology in an engineering environment

    International Nuclear Information System (INIS)

    Powell, A.D.; Sokolowski, M.A.

    1990-01-01

    This paper reports on the application of local area network technology in an engineering environment. Mobil Research and Development Corporation Engineering, Dallas, texas has installed a local area network (LAN) linking over 85 microcomputers. This network, which has been in existence for more than three years, provides common access by all engineers to quality output devices such as laser printers and multi-color pen plotters; IBM mainframe connections; electronic mail and file transfer; and common engineering program. The network has been expanded via a wide area ethernet network to link the Dallas location with a functionally equivalent LAN of over 400 microcomputers in Princeton, N.J. Additionally, engineers on assignment at remote areas in Europe, U.S., Africa and project task forces have dial-in access to the network via telephone lines

  8. Evolutionary engineering of industrial microorganisms-strategies and applications.

    Science.gov (United States)

    Zhu, Zhengming; Zhang, Juan; Ji, Xiaomei; Fang, Zhen; Wu, Zhimeng; Chen, Jian; Du, Guocheng

    2018-06-01

    Microbial cells have been widely used in the industry to obtain various biochemical products, and evolutionary engineering is a common method in biological research to improve their traits, such as high environmental tolerance and improvement of product yield. To obtain better integrate functions of microbial cells, evolutionary engineering combined with other biotechnologies have attracted more attention in recent years. Classical laboratory evolution has been proven effective to letting more beneficial mutations occur in different genes but also has some inherent limitations such as a long evolutionary period and uncontrolled mutation frequencies. However, recent studies showed that some new strategies may gradually overcome these limitations. In this review, we summarize the evolutionary strategies commonly used in industrial microorganisms and discuss the combination of evolutionary engineering with other biotechnologies such as systems biology and inverse metabolic engineering. Finally, we prospect the importance and application prospect of evolutionary engineering as a powerful tool especially in optimization of industrial microbial cell factories.

  9. The development and application of CFD technology in mechanical engineering

    Science.gov (United States)

    Wei, Yufeng

    2017-12-01

    Computational Fluid Dynamics (CFD) is an analysis of the physical phenomena involved in fluid flow and heat conduction by computer numerical calculation and graphical display. The numerical method simulates the complexity of the physical problem and the precision of the numerical solution, which is directly related to the hardware speed of the computer and the hardware such as memory. With the continuous improvement of computer performance and CFD technology, it has been widely applied to the field of water conservancy engineering, environmental engineering and industrial engineering. This paper summarizes the development process of CFD, the theoretical basis, the governing equations of fluid mechanics, and introduces the various methods of numerical calculation and the related development of CFD technology. Finally, CFD technology in the mechanical engineering related applications are summarized. It is hoped that this review will help researchers in the field of mechanical engineering.

  10. A software engineering process for safety-critical software application

    International Nuclear Information System (INIS)

    Kang, Byung Heon; Kim, Hang Bae; Chang, Hoon Seon; Jeon, Jong Sun

    1995-01-01

    Application of computer software to safety-critical systems in on the increase. To be successful, the software must be designed and constructed to meet the functional and performance requirements of the system. For safety reason, the software must be demonstrated not only to meet these requirements, but also to operate safely as a component within the system. For longer-term cost consideration, the software must be designed and structured to ease future maintenance and modifications. This paper presents a software engineering process for the production of safety-critical software for a nuclear power plant. The presentation is expository in nature of a viable high quality safety-critical software development. It is based on the ideas of a rational design process and on the experience of the adaptation of such process in the production of the safety-critical software for the shutdown system number two of Wolsung 2, 3 and 4 nuclear power generation plants. This process is significantly different from a conventional process in terms of rigorous software development phases and software design techniques, The process covers documentation, design, verification and testing using mathematically precise notations and highly reviewable tabular format to specify software requirements and software requirements and software requirements and code against software design using static analysis. The software engineering process described in this paper applies the principle of information-hiding decomposition in software design using a modular design technique so that when a change is required or an error is detected, the affected scope can be readily and confidently located. it also facilitates a sense of high degree of confidence in the 'correctness' of the software production, and provides a relatively simple and straightforward code implementation effort. 1 figs., 10 refs. (Author)

  11. Advanced materials and protective coatings in aero-engines application

    OpenAIRE

    M. Hetmańczyk; L. Swadźba; B. Mendala

    2007-01-01

    Purpose: The following article demonstrates the characteristics of the materials applied as parts of aircraft engine turbines and the stationary gas turbines. The principal technologies for manufacturing the heat resistant coatings and the erosion and corrosion resistant coatings were characterized. Sample applications for the aforementioned coatings are presented: on turbine blades, compressor blades and on parts of combustion chambers of aircraft engines.Design/methodology/approach: The nic...

  12. Applications of computational modeling in metabolic engineering of yeast

    DEFF Research Database (Denmark)

    Kerkhoven, Eduard J.; Lahtvee, Petri-Jaan; Nielsen, Jens

    2015-01-01

    a preferred flux distribution. These methods point to strategies for altering gene expression; however, fluxes are often controlled by post-transcriptional events. Moreover, GEMs are usually not taking into account metabolic regulation, thermodynamics and enzyme kinetics. To facilitate metabolic engineering......, it is necessary to expand the modeling of metabolism to consider kinetics of individual processes. This review will give an overview about models available for metabolic engineering of yeast and discusses their applications....

  13. Rational engineering of physicochemical properties of nanomaterials for biomedical applications with nanotoxicological perspectives.

    Science.gov (United States)

    Navya, P N; Daima, Hemant Kumar

    2016-01-01

    Innovative engineered nanomaterials are at the leading edge of rapidly emerging fields of nanobiotechnology and nanomedicine. Meticulous synthesis, unique physicochemical properties, manifestation of chemical or biological moieties on the surface of materials make engineered nanostructures suitable for a variety of biomedical applications. Besides, tailored nanomaterials exhibit entirely novel therapeutic applications with better functionality, sensitivity, efficiency and specificity due to their customized unique physicochemical and surface properties. Additionally, such designer made nanomaterials has potential to generate series of interactions with various biological entities including DNA, proteins, membranes, cells and organelles at nano-bio interface. These nano-bio interactions are driven by colloidal forces and predominantly depend on the dynamic physicochemical and surface properties of nanomaterials. Nevertheless, recent development and atomic scale tailoring of various physical, chemical and surface properties of nanomaterials is promising to dictate their interaction in anticipated manner with biological entities for biomedical applications. As a result, rationally designed nanomaterials are in extensive demand for bio-molecular detection and diagnostics, therapeutics, drug and gene delivery, fluorescent labelling, tissue engineering, biochemical sensing and other pharmaceuticals applications. However, toxicity and risk associated with engineered nanomaterials is rather unclear or not well understood; which is gaining considerable attention and the field of nanotoxicology is evolving promptly. Therefore, this review explores current knowledge of articulate engineering of nanomaterials for biomedical applications with special attention on potential toxicological perspectives.

  14. Engineered magnetic nanoparticles for biomedical applications.

    Science.gov (United States)

    Canfarotta, Francesco; Piletsky, Sergey A

    2014-02-01

    In the past decades, magnetic nanoparticles (MNPs) have been used in wide range of diverse applications, ranging from separation to sensing. Here, synthesis and applications of functionalized MNPs in the biomedical field are discussed, in particular in drug delivery, imaging, and cancer therapy, highlighting also recent progresses in the development of multifunctional and stimuli-responsive MNPs. The role of their size, composition, and surface functionalization is analyzed, together with their biocompatibility issues. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Software engineering with application-specific languages

    Science.gov (United States)

    Campbell, David J.; Barker, Linda; Mitchell, Deborah; Pollack, Robert H.

    1993-01-01

    Application-Specific Languages (ASL's) are small, special-purpose languages that are targeted to solve a specific class of problems. Using ASL's on software development projects can provide considerable cost savings, reduce risk, and enhance quality and reliability. ASL's provide a platform for reuse within a project or across many projects and enable less-experienced programmers to tap into the expertise of application-area experts. ASL's have been used on several software development projects for the Space Shuttle Program. On these projects, the use of ASL's resulted in considerable cost savings over conventional development techniques. Two of these projects are described.

  16. Applicability of advanced automotive heat engines to solar thermal power

    Science.gov (United States)

    Beremand, D. G.; Evans, D. G.; Alger, D. L.

    The requirements of a solar thermal power system are reviewed and compared with the predicted characteristics of automobile engines under development. A good match is found in terms of power level and efficiency when the automobile engines, designed for maximum powers of 65-100 kW (87 to 133 hp) are operated to the nominal 20-40 kW electric output requirement of the solar thermal application. At these reduced power levels it appears that the automotive gas turbine and Stirling engines have the potential to deliver the 40+ percent efficiency goal of the solar thermal program.

  17. Protein engineering of enzymes for process applications

    DEFF Research Database (Denmark)

    Woodley, John M

    2013-01-01

    opportunities will be targeted on modification to enable process application. This article discusses the challenges involved in enzyme modification focused on process requirements, such as the need to fulfill reaction thermodynamics, specific activity under the required conditions, kinetics at required...... concentrations, and stability. Finally, future research directions are discussed, including the integration of biocatalysis with neighboring chemical steps....

  18. Mathematical modeling and computational intelligence in engineering applications

    CERN Document Server

    Silva Neto, Antônio José da; Silva, Geraldo Nunes

    2016-01-01

    This book brings together a rich selection of studies in mathematical modeling and computational intelligence, with application in several fields of engineering, like automation, biomedical, chemical, civil, electrical, electronic, geophysical and mechanical engineering, on a multidisciplinary approach. Authors from five countries and 16 different research centers contribute with their expertise in both the fundamentals and real problems applications based upon their strong background on modeling and computational intelligence. The reader will find a wide variety of applications, mathematical and computational tools and original results, all presented with rigorous mathematical procedures. This work is intended for use in graduate courses of engineering, applied mathematics and applied computation where tools as mathematical and computational modeling, numerical methods and computational intelligence are applied to the solution of real problems.

  19. CVD diamond for nuclear detection applications

    International Nuclear Information System (INIS)

    Bergonzo, P.; Brambilla, A.; Tromson, D.; Mer, C.; Guizard, B.; Marshall, R.D.; Foulon, F.

    2002-01-01

    Chemically vapour deposited (CVD) diamond is a remarkable material for the fabrication of radiation detectors. In fact, there exist several applications where other standard semiconductor detectors do not fulfil the specific requirements imposed by corrosive, hot and/or high radiation dose environments. The improvement of the electronic properties of CVD diamond has been under intensive investigations and led to the development of a few applications that are addressing specific industrial needs. Here, we report on CVD diamond-based detector developments and we describe how this material, even though of a polycrystalline nature, is readily of great interest for applications in the nuclear industry as well as for physics experiments. Improvements in the material synthesis as well as on device fabrication especially concern the synthesis of films that do not exhibit space charge build up effects which are often encountered in CVD diamond materials and that are highly detrimental for detection devices. On a pre-industrial basis, CVD diamond detectors have been fabricated for nuclear industry applications in hostile environments. Such devices can operate in harsh environments and overcome limitations encountered with the standard semiconductor materials. Of these, this paper presents devices for the monitoring of the alpha activity in corrosive nuclear waste solutions, such as those encountered in nuclear fuel assembly reprocessing facilities, as well as diamond-based thermal neutron detectors exhibiting a high neutron to gamma selectivity. All these demonstrate the effectiveness of a demanding industrial need that relies on the remarkable resilience of CVD diamond

  20. Radiation Detection for Homeland Security Applications

    Science.gov (United States)

    Ely, James

    2008-05-01

    In the past twenty years or so, there have been significant changes in the strategy and applications for homeland security. Recently there have been significant at deterring and interdicting terrorists and associated organizations. This is a shift in the normal paradigm of deterrence and surveillance of a nation and the `conventional' methods of warfare to the `unconventional' means that terrorist organizations resort to. With that shift comes the responsibility to monitor international borders for weapons of mass destruction, including radiological weapons. As a result, countries around the world are deploying radiation detection instrumentation to interdict the illegal shipment of radioactive material crossing international borders. These efforts include deployments at land, rail, air, and sea ports of entry in the US and in European and Asian countries. Radioactive signatures of concern include radiation dispersal devices (RDD), nuclear warheads, and special nuclear material (SNM). Radiation portal monitors (RPMs) are used as the main screening tool for vehicles and cargo at borders, supplemented by handheld detectors, personal radiation detectors, and x-ray imaging systems. This talk will present an overview of radiation detection equipment with emphasis on radiation portal monitors. In the US, the deployment of radiation detection equipment is being coordinated by the Domestic Nuclear Detection Office within the Department of Homeland Security, and a brief summary of the program will be covered. Challenges with current generation systems will be discussed as well as areas of investigation and opportunities for improvements. The next generation of radiation portal monitors is being produced under the Advanced Spectroscopic Portal program and will be available for deployment in the near future. Additional technologies, from commercially available to experimental, that provide additional information for radiation screening, such as density imaging equipment, will

  1. Artificial hammerhead ribozymes: engineering and applications

    International Nuclear Information System (INIS)

    Vorobjeva, M A; Davydova, A S; Venyaminova, Aliya G

    2011-01-01

    The properties of hammerhead ribozymes are described. Various hammerhead ribozyme constructs for target RNA cleavage were considered. Approaches to enhancement of the stability of artificial ribozymes in biological media and to regulation of the catalytic activity of hammerhead ribozymes using effector molecules are described. The effect of ribozymes on extended structured natural RNAs is discussed. Applications of artificial hammerhead ribozymes as inhibitors of gene expression at matrix RNA level were considered.

  2. Qualitative knowledge engineering for nuclear applications

    International Nuclear Information System (INIS)

    Kim, Jae H.; Kim, Ko R.; Lee, Jae C.

    1996-01-01

    After the TMI nuclear power plant accident, the two topics of plant safety and operational efficiency became more important areas of artificial intelligence, which have difference characteristics. Qualitative deep model is the recently prospective technology of AI, that can overcome several handicaps of the existing expert systems such as lack of common sense reasoning. The application of AI to the large and complex system like nuclear power plants is typically and effectively done through a module-based hierarchical system. As each module has to be built with suitable AI system. Through the experiences of hierarchical system construction, we aimed to develop basic AI application schemes for the power plant safety and operational efficiency as well as basic technologies for autonomous power plants. The goal of the research is to develop qualitative reasoning technologies for nuclear power plants. For this purpose, the development of qualitative modeling technologies and qualitative behaviour prediction technologies of the power plant are accomplished. In addition, the feasibility of application of typical qualitative reasoning technologies to power plants is studied . The goal of the application is to develop intelligent control technologies of power plants, support technologies. For these purposes, we analyzed the operation of power plants according to its operation purpose: power generation operation, shut-down and start-up operation. As a result, qualitative model of basic components were sketched, including pipes, valves, pumps and heat exchangers. Finally, plant behaviour prediction technologies through qualitative plant heat transfer model and design support technologies through 2nd-order differential equation were developed. For the construction of AI system of power plants, we have studied on the mixed module based hierarchical software. As a testbed, we have considered the spent fuel system and the feedwater system. We also studied the integration

  3. Introduction to Plasma Technology Science, Engineering and Applications

    CERN Document Server

    Harry, John Ernest

    2011-01-01

    Written by a university lecturer with more than forty years experience in plasma technology, this book adopts a didactic approach in its coverage of the theory, engineering and applications of technological plasmas. The theory is developed in a unified way to enable brevity and clarity, providing readers with the necessary background to assess the factors that affect the behavior of plasmas under different operating conditions. The major part of the book is devoted to the applications of plasma technology and their accompanying engineering aspects, classified by the various pressure and densit

  4. Fuzzy Sets Applications in Civil Engineering Basic Areas

    Directory of Open Access Journals (Sweden)

    Latif Onur UĞUR

    2016-01-01

    Full Text Available Civil engineering is a professional engineering discipline that deals with the design, construction, and maintenance of the physical and naturally built environment, including works like roads, bridges, canals, dams, and buildings. This paper presents some Fuzzy Logic (FL applications in civil engeering discipline and shows the potential of facilities of FL in this area. The potential role of fuzzy sets in analysing system and human uncertainty is investigated in the paper. The main finding of this inquiry is FL applications used in different areas of civil engeering discipline with success. Once developed, the fuzzy logic models can be used for further monitoring activities, as a management tool.

  5. Implementation of Scientific Computing Applications on the Cell Broadband Engine

    Directory of Open Access Journals (Sweden)

    Guochun Shi

    2009-01-01

    Full Text Available The Cell Broadband Engine architecture is a revolutionary processor architecture well suited for many scientific codes. This paper reports on an effort to implement several traditional high-performance scientific computing applications on the Cell Broadband Engine processor, including molecular dynamics, quantum chromodynamics and quantum chemistry codes. The paper discusses data and code restructuring strategies necessary to adapt the applications to the intrinsic properties of the Cell processor and demonstrates performance improvements achieved on the Cell architecture. It concludes with the lessons learned and provides practical recommendations on optimization techniques that are believed to be most appropriate.

  6. Applications of pattern recognition techniques to online fault detection

    International Nuclear Information System (INIS)

    Singer, R.M.; Gross, K.C.; King, R.W.

    1993-01-01

    A common problem to operators of complex industrial systems is the early detection of incipient degradation of sensors and components in order to avoid unplanned outages, to orderly plan for anticipated maintenance activities and to assure continued safe operation. In such systems, there usually are a large number of sensors (upwards of several thousand is not uncommon) serving many functions, ranging from input to control systems, monitoring of safety parameters and component performance limits, system environmental conditions, etc. Although sensors deemed to measure important process conditions are generally alarmed, the alarm set points usually are just high-low limits and the operator's response to such alarms is based on written procedures and his or her experience and training. In many systems this approach has been successful, but in situations where the cost of a forced outage is high an improved method is needed. In such cases it is desirable, if not necessary, to detect disturbances in either sensors or the process prior to any actual failure that could either shut down the process or challenge any safety system that is present. Recent advances in various artificial intelligence techniques have provided the opportunity to perform such functions of early detection and diagnosis. In this paper, the experience gained through the application of several pattern-recognition techniques to the on-line monitoring and incipient disturbance detection of several coolant pumps and numerous sensors at the Experimental Breeder Reactor-II (EBR-II) which is located at the Idaho National Engineering Laboratory is presented

  7. Nanostructure Engineered Chemical Sensors for Hazardous Gas and Vapor Detection

    Science.gov (United States)

    Li, Jing; Lu, Yijiang

    2005-01-01

    A nanosensor technology has been developed using nanostructures, such as single walled carbon nanotubes (SWNTs) and metal oxides nanowires or nanobelts, on a pair of interdigitated electrodes (IDE) processed with a silicon based microfabrication and micromachining technique. The IDE fingers were fabricated using thin film metallization techniques. Both in-situ growth of nanostructure materials and casting of the nanostructure dispersions were used to make chemical sensing devices. These sensors have been exposed to hazardous gases and vapors, such as acetone, benzene, chlorine, and ammonia in the concentration range of ppm to ppb at room temperature. The electronic molecular sensing in our sensor platform can be understood by electron modulation between the nanostructure engineered device and gas molecules. As a result of the electron modulation, the conductance of nanodevice will change. Due to the large surface area, low surface energy barrier and high thermal and mechanical stability, nanostructured chemical sensors potentially can offer higher sensitivity, lower power consumption and better robustness than the state-of-the-art systems, which make them more attractive for defense and space applications. Combined with MEMS technology, light weight and compact size sensors can be made in wafer scale with low cost.

  8. Solar energy sciences and engineering applications

    CERN Document Server

    Enteria, Napoleon

    2013-01-01

    Solar energy is available all over the world in different intensities. Theoretically, the solar energy available on the surface of the earth is enough to support the energy requirements of the entire planet. However, in reality, progress and development of solar science and technology depends to a large extent on human desires and needs. This is due to the various barriers to overcome and to deal with the economics of practical utilization of solar energy.This book will introduce the rapid development and progress in the field of solar energy applications for science and technology: the advanc

  9. Applications of observational techniques in pavement engineering

    CSIR Research Space (South Africa)

    Steyn, WJVDM

    2007-05-01

    Full Text Available available at CSIR BE. The technology used to obtain the images at each of the resolutions and wavelengths, as well as the benefits and limitations and typical applications of the groups of images are as follows: 3.1 Visible waveband, Mm resolution... of technology enabled an increase in the scope of potential observations that is spreading towards the larger and smaller realms of visibility. In this sense observations can be made on a scale from very large artefacts (such as the earth) to very small...

  10. 46 CFR 113.35-15 - Mechanical engine order telegraph systems; application.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

  11. LCCP Desktop Application v1.0 Engineering Reference

    Energy Technology Data Exchange (ETDEWEB)

    Beshr, Mohamed [Univ. of Maryland, College Park, MD (United States); Aute, Vikrant [Univ. of Maryland, College Park, MD (United States)

    2014-04-01

    This Life Cycle Climate Performance (LCCP) Desktop Application Engineering Reference is divided into three parts. The first part of the guide, consisting of the LCCP objective, literature review, and mathematical background, is presented in Sections 2-4. The second part of the guide (given in Sections 5-10) provides a description of the input data required by the LCCP desktop application, including each of the input pages (Application Information, Load Information, and Simulation Information) and details for interfacing the LCCP Desktop Application with the VapCyc and EnergyPlus simulation programs. The third part of the guide (given in Section 11) describes the various interfaces of the LCCP code.

  12. Optimized application of systems engineering to nuclear waste repository projects

    International Nuclear Information System (INIS)

    Miskimin, P.A.; Shepard, M.

    1986-01-01

    The purpose of this presentation is to describe a fully optimized application of systems engineering methods and philosophy to the management of a large nuclear waste repository project. Knowledge gained from actual experience with the use of the systems approach on two repository projects is incorporated in the material presented. The projects are currently evaluating the isolation performance of different geologic settings and are in different phases of maturity. Systems engineering methods were applied by the principal author at the Waste Isolation Pilot Plant (WIPP) in the form of a functional analysis. At the Basalt Waste Isolation Project (BWIP), the authors assisted the intergrating contractor with the development and application of systems engineering methods. Based on this experience and that acquired from other waste management projects, an optimized plan for applying systems engineering techniques was developed. The plan encompasses the following aspects: project organization, developing and defining requirements, assigning work responsibilities, evaluating system performance, quality assurance, controlling changes, enhancing licensability, optimizing project performance, and addressing regulatory issues. This information is presented in the form of a roadmap for the practical application of system engineering principles to a nuclear waste repository project

  13. Bioreactors in tissue engineering - principles, applications and commercial constraints.

    Science.gov (United States)

    Hansmann, Jan; Groeber, Florian; Kahlig, Alexander; Kleinhans, Claudia; Walles, Heike

    2013-03-01

    Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide a tissue-specific physiological in vitro environment during tissue maturation. In addition to this most obvious application, bioreactors have the potential to improve the efficiency of the overall tissue-engineering concept. To date, a variety of bioreactor systems for tissue-specific applications have been developed. Of these, some systems are already commercially available. With bioreactor technology, various functional tissues of different types were generated and cultured in vitro. Nevertheless, these efforts and achievements alone have not yet led to many clinically successful tissue-engineered implants. We review possible applications for bioreactor systems within a tissue-engineering process and present basic principles and requirements for bioreactor development. Moreover, the use of bioreactor systems for the expansion of clinically relevant cell types is addressed. In contrast to cell expansion, for the generation of functional three-dimensional tissue equivalents, additional physical cues must be provided. Therefore, bioreactors for musculoskeletal tissue engineering are discussed. Finally, bioreactor technology is reviewed in the context of commercial constraints. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Evaluation of undeveloped rocket engine cycle applications to advanced transportation

    Science.gov (United States)

    1990-01-01

    Undeveloped pump-fed, liquid propellant rocket engine cycles were assessed and evaluated for application to Next Manned Transportation System (NMTS) vehicles, which would include the evolving Space Transportation System (STS Evolution), the Personnel Launch System (PLS), and the Advanced Manned Launch System (AMLS). Undeveloped engine cycles selected for further analysis had potential for increased reliability, more maintainability, reduced cost, and improved (or possibly level) performance when compared to the existing SSME and proposed STME engines. The split expander (SX) cycle, the full flow staged combustion (FFSC) cycle, and a hybrid version of the FFSC, which has a LOX expander drive for the LOX pump, were selected for definition and analysis. Technology requirements and issues were identified and analyses of vehicle systems weight deltas using the SX and FFSC cycles in AMLS vehicles were performed. A strawman schedule and cost estimate for FFSC subsystem technology developments and integrated engine system demonstration was also provided.

  15. Using hybrid expert system approaches for engineering applications

    Science.gov (United States)

    Allen, R. H.; Boarnet, M. G.; Culbert, C. J.; Savely, R. T.

    1987-01-01

    In this paper, the use of hybrid expert system shells and hybrid (i.e., algorithmic and heuristic) approaches for solving engineering problems is reported. Aspects of various engineering problem domains are reviewed for a number of examples with specific applications made to recently developed prototype expert systems. Based on this prototyping experience, critical evaluations of and comparisons between commercially available tools, and some research tools, in the United States and Australia, and their underlying problem-solving paradigms are made. Characteristics of the implementation tool and the engineering domain are compared and practical software engineering issues are discussed with respect to hybrid tools and approaches. Finally, guidelines are offered with the hope that expert system development will be less time consuming, more effective, and more cost-effective than it has been in the past.

  16. Computational electromagnetics recent advances and engineering applications

    CERN Document Server

    2014-01-01

    Emerging Topics in Computational Electromagnetics in Computational Electromagnetics presents advances in Computational Electromagnetics. This book is designed to fill the existing gap in current CEM literature that only cover the conventional numerical techniques for solving traditional EM problems. The book examines new algorithms, and applications of these algorithms for solving problems of current interest that are not readily amenable to efficient treatment by using the existing techniques. The authors discuss solution techniques for problems arising in nanotechnology, bioEM, metamaterials, as well as multiscale problems. They present techniques that utilize recent advances in computer technology, such as parallel architectures, and the increasing need to solve large and complex problems in a time efficient manner by using highly scalable algorithms.

  17. Phenomenological BRDF modeling for engineering applications

    Science.gov (United States)

    Jafolla, James C.; Stokes, Jeffrey A.; Sullivan, Robert J.

    1997-09-01

    The application of analytical light scattering techniques for virtual prototyping the optical performance of paint coatings provides an effective tool for optimizing paint design for specific optical requirements. This paper describes the phenomenological basis for the scattering coatings computer aided design (ScatCad) code. The ScatCad code predicts the bidirectional reflectance distribution function (BRDF) and the hemispherical directional reflectance (HDR) of pigmented paint coatings for the purpose of coating design optimization. The code uses techniques for computing the pigment single scattering phase function, multiple scattering radiative transfer, and rough surface scattering to calculate the BRDF and HDR based on the fundamental optical properties of the pigment(s) and binder, pigment number density and size distribution, and surface roughness of the binder-interface and substrate. This is a significant enhancement to the two- flux, Kubelka-Munk analysis that has traditionally been used in the coatings industry. Example calculations and comparison with measurements are also presented.

  18. 4th International Conference in Software Engineering for Defence Applications

    CERN Document Server

    Sillitti, Alberto; Succi, Giancarlo; Messina, Angelo

    2016-01-01

    This book presents high-quality original contributions on new software engineering models, approaches, methods, and tools and their evaluation in the context of defence and security applications. In addition, important business and economic aspects are discussed, with a particular focus on cost/benefit analysis, new business models, organizational evolution, and business intelligence systems. The contents are based on presentations delivered at SEDA 2015, the 4th International Conference in Software Engineering for Defence Applications, which was held in Rome, Italy, in May 2015. This conference series represents a targeted response to the growing need for research that reports and debates the practical implications of software engineering within the defence environment and also for software performance evaluation in real settings through controlled experiments as well as case and field studies. The book will appeal to all with an interest in modeling, managing, and implementing defence-related software devel...

  19. System Engineering of Photonic Systems for Space Application

    Science.gov (United States)

    Watson, Michael D.; Pryor, Jonathan E.

    2014-01-01

    The application of photonics in space systems requires tight integration with the spacecraft systems to ensure accurate operation. This requires some detailed and specific system engineering to properly incorporate the photonics into the spacecraft architecture and to guide the spacecraft architecture in supporting the photonics devices. Recent research in product focused, elegant system engineering has led to a system approach which provides a robust approach to this integration. Focusing on the mission application and the integration of the spacecraft system physics incorporation of the photonics can be efficiently and effectively accomplished. This requires a clear understanding of the driving physics properties of the photonics device to ensure proper integration with no unintended consequences. The driving physics considerations in terms of optical performance will be identified for their use in system integration. Keywords: System Engineering, Optical Transfer Function, Optical Physics, Photonics, Image Jitter, Launch Vehicle, System Integration, Organizational Interaction

  20. Engineering mechanical microenvironment of macrophage and its biomedical applications.

    Science.gov (United States)

    Li, Jing; Li, Yuhui; Gao, Bin; Qin, Chuanguang; He, Yining; Xu, Feng; Yang, Hui; Lin, Min

    2018-03-01

    Macrophages are the most plastic cells in the hematopoietic system and can be widely found in almost all tissues. Recently studies have shown that mechanical cues (e.g., matrix stiffness and stress/strain) can significantly affect macrophage behaviors. Although existing reviews on the physical and mechanical cues that regulate the macrophage's phenotype are available, engineering mechanical microenvironment of macrophages in vitro as well as a comprehensive overview and prospects for their biomedical applications (e.g., tissue engineering and immunotherapy) has yet to be summarized. Thus, this review provides an overview on the existing methods for engineering mechanical microenvironment of macrophages in vitro and then a section on their biomedical applications and further perspectives are presented.

  1. Advance elements of optoisolation circuits nonlinearity applications in engineering

    CERN Document Server

    Aluf, Ofer

    2017-01-01

    This book on advanced optoisolation circuits for nonlinearity applications in engineering addresses two separate engineering and scientific areas, and presents advanced analysis methods for optoisolation circuits that cover a broad range of engineering applications. The book analyzes optoisolation circuits as linear and nonlinear dynamical systems and their limit cycles, bifurcation, and limit cycle stability by using Floquet theory. Further, it discusses a broad range of bifurcations related to optoisolation systems: cusp-catastrophe, Bautin bifurcation, Andronov-Hopf bifurcation, Bogdanov-Takens (BT) bifurcation, fold Hopf bifurcation, Hopf-Hopf bifurcation, Torus bifurcation (Neimark-Sacker bifurcation), and Saddle-loop or Homoclinic bifurcation. Floquet theory helps as to analyze advance optoisolation systems. Floquet theory is the study of the stability of linear periodic systems in continuous time. Another way to describe Floquet theory, it is the study of linear systems of differential equations with p...

  2. Qualitative knowledge engineering for nuclear applications

    International Nuclear Information System (INIS)

    Kim, Jae H.; Kim, Ko R.; Lee, Jae C.; Choi, You R.

    1998-01-01

    After the TMI nuclear power plant accident, plant safety and operational efficiency became more important areas of artificial intelligence. They need to build artificial intelligence systems which can predict and explain plant behaviors in earlier phases. We have a 3-year plan to develop hybrid modeling technology of artificial intelligence and related prototype subsystems. After concept design of autonomous power plant in the first year, basic and essential AI technologies were studied and applied to nuclear power plant subsystems, such as the underwater bubble detection subsystem and the eddy current test (ECT) subsystem this year. We developed diagnostic algorithm and experimented it on a testbed we prepared. The testbed system consists of ultrasonic sensor arrays and signal processors, which generates bubble image data and ultrasonic signal distribution data. The essential algorithm to guess the bubble image and its position was studied and developed using two different technologies: the neural network technology and the ultrasonic tomography technology. We developed diagnostic algorithms through ECT data analysis and applied it on an ECT subsystem. During the analysis of ECT data, we concentrated on structure analysis of physical data and internal data, and especially on segmentation scheme of ECT data. The diagnostic algorithm was studied and developed using two different technologies: Fourier descriptors technology and neural network technology. In order to verify the diagnostic algorithms, we have developed the prototype diagnostic programs which proved its good performance. (author). 15 refs., 5 tabs., 25 figs

  3. Handbook of power systems engineering with power electronics applications

    CERN Document Server

    Hase, Yoshihide

    2012-01-01

    Formerly known as Handbook of Power System Engineering, this second edition provides rigorous revisions to the original treatment of systems analysis together with a substantial new four-chapter section on power electronics applications. Encompassing a whole range of equipment, phenomena, and analytical approaches, this handbook offers a complete overview of power systems and their power electronics applications, and presents a thorough examination of the fundamental principles, combining theories and technologies that are usually treated in separate specialised fields, in a single u

  4. Droplet-Wall/Film Impact in IC Engine Applications

    Science.gov (United States)

    2017-08-14

    Report: Droplet-Wall/ Film Impact in IC Engine Applications (ARO Topic 1.4.1 under ARO’s Dr. Ralph A. Anthenien) The views, opinions and/or findings...Participants: RPPR Final Report as of 12-Oct-2017 Agreement Number: W911NF-16-1-0449 Organization: Princeton University Title: Droplet-Wall/ Film Impact...droplets impacting a wet surface under various film thickness, which plays a critical role in controlling the efficiency of applications such as those

  5. Engineered nonviral nanocarriers for intracellular gene delivery applications

    International Nuclear Information System (INIS)

    Ojea-Jiménez, Isaac; Puntes, Victor F; Tort, Olivia; Lorenzo, Julia

    2012-01-01

    The efficient delivery of nucleic acids into mammalian cells is a central aspect of cell biology and of medical applications, including cancer therapy and tissue engineering. Non-viral chemical methods have been received with great interest for transfecting cells. However, further development of nanocarriers that are biocompatible, efficient and suitable for clinical applications is still required. In this paper, the different material platforms for gene delivery are comparatively addressed, and the mechanisms of interaction with biological systems are discussed carefully. (paper)

  6. Applications of Green's functions in science and engineering

    CERN Document Server

    Greenberg, Michael D

    2015-01-01

    Concise and highly regarded, this treatment of Green's functions and their applications in science and engineering is geared toward undergraduate and graduate students with only a moderate background in ordinary differential equations and partial differential equations. The text also includes a wealth of information of a more general nature on boundary value problems, generalized functions, eigenfunction expansions, partial differential equations, and acoustics. The two-part treatment begins with an overview of applications to ordinary differential equations. Topics include the adjoint operato

  7. Detection of combustion start in the controlled auto ignition engine by wavelet transform of the engine block vibration signal

    International Nuclear Information System (INIS)

    Kim, Seonguk; Min, Kyoungdoug

    2008-01-01

    The CAI (controlled auto ignition) engine ignites fuel and air mixture by trapping high temperature burnt gas using a negative valve overlap. Due to auto ignition in CAI combustion, efficiency improvements and low level NO x emission can be obtained. Meanwhile, the CAI combustion regime is restricted and control parameters are limited. The start of combustion data in the compressed ignition engine are most critical for controlling the overall combustion. In this research, the engine block vibration signal is transformed by the Meyer wavelet to analyze CAI combustion more easily and accurately. Signal acquisition of the engine block vibration is a more suitable method for practical use than measurement of in-cylinder pressure. A new method for detecting combustion start in CAI engines through wavelet transformation of the engine block vibration signal was developed and results indicate that it is accurate enough to analyze the start of combustion. Experimental results show that wavelet transformation of engine block vibration can track the start of combustion in each cycle. From this newly developed method, the start of combustion data in CAI engines can be detected more easily and used as input data for controlling CAI combustion

  8. Detection of combustion start in the controlled auto ignition engine by wavelet transform of the engine block vibration signal

    Science.gov (United States)

    Kim, Seonguk; Min, Kyoungdoug

    2008-08-01

    The CAI (controlled auto ignition) engine ignites fuel and air mixture by trapping high temperature burnt gas using a negative valve overlap. Due to auto ignition in CAI combustion, efficiency improvements and low level NOx emission can be obtained. Meanwhile, the CAI combustion regime is restricted and control parameters are limited. The start of combustion data in the compressed ignition engine are most critical for controlling the overall combustion. In this research, the engine block vibration signal is transformed by the Meyer wavelet to analyze CAI combustion more easily and accurately. Signal acquisition of the engine block vibration is a more suitable method for practical use than measurement of in-cylinder pressure. A new method for detecting combustion start in CAI engines through wavelet transformation of the engine block vibration signal was developed and results indicate that it is accurate enough to analyze the start of combustion. Experimental results show that wavelet transformation of engine block vibration can track the start of combustion in each cycle. From this newly developed method, the start of combustion data in CAI engines can be detected more easily and used as input data for controlling CAI combustion.

  9. Off reactor testings. Technological engineering applicative research

    International Nuclear Information System (INIS)

    Doca, Cezar

    2001-01-01

    By the end of year 2000 over 400 nuclear electro-power units were operating world wide, summing up a 350,000 MW total capacity, with a total production of 2,300 TWh, representing 16% of the world's electricity production. Other 36 units, totalizing 28,000 MW, were in construction, while a manifest orientation towards nuclear power development was observed in principal Asian countries like China, India, Japan and Korea. In the same world's trend one find also Romania, the Cernavoda NPP Unit 1 generating electrical energy into the national system beginning with 2 December 1996. Recently, the commercial contract was completed for finishing the Cernavoda NPP Unit 2 and launching it into operation by the end of year 2004. An important role in developing the activity of research and technological engineering, as technical support for manufacturing the CANDU type nuclear fuel and supplying with equipment the Cernavoda units, was played by the Division 7 TAR of the INR Pitesti. Qualification testings were conducted for: - off-reactor CANDU type nuclear fuel; - FARE tools, pressure regulators, explosion proof panels; channel shutting, as well as functional testing for spare pushing facility as a first step in the frame of the qualification tests for the charging/discharging machine (MID) 4 and 5 endings. Testing facilities are described, as well as high pressure hot/cool loops, measuring chains, all of them fulfilling the requirements of quality assurance. The nuclear fuel off-reactor tests were carried out to determine: strength; endurance; impact, pressure fall and wear resistance. For Cernavoda NPP equipment testings were carried out for: the explosion proof panels, pressure regulators, behaviour to vibration and wear of the steam generation tubings, effects of vibration upon different electronic component, channel shutting (for Cernavoda Unit 2), MID operating at 300 and 500 cycles. A number of R and D programs were conducted in the frame of division 7 TAR of INR

  10. Application of Plagiarism Screening Software in the Chemical Engineering Curriculum

    Science.gov (United States)

    Cooper, Matthew E.; Bullard, Lisa G.

    2014-01-01

    Plagiarism is an area of increasing concern for written ChE assignments, such as laboratory and design reports, due to ease of access to text and other materials via the internet. This study examines the application of plagiarism screening software to four courses in a university chemical engineering curriculum. The effectiveness of plagiarism…

  11. Enzymatically biomineralized chitosan scaffolds for tissue-engineering applications.

    NARCIS (Netherlands)

    Dash, M.; Samal, S.K.; Douglas, T.E.L.; Schaubroeck, D.; Leeuwenburgh, S.C.G.; Voort, P. van der; Declercq, H.A.; Dubruel, P.

    2017-01-01

    Porous biodegradable scaffolds represent promising candidates for tissue-engineering applications because of their capability to be preseeded with cells. We report an uncrosslinked chitosan scaffold designed with the aim of inducing and supporting enzyme-mediated formation of apatite minerals in the

  12. Plant cell engineering: current research, application and future prospects

    International Nuclear Information System (INIS)

    Wang Xunqing; Liu Luxiang

    2008-01-01

    This paper reviewed the current status of basic research in plant cell engineering, highlighted the application of embryo culture, double haploid (DH) technology, protoplast culture and somatic hybridization, somaclonal variation, rapid propagation, and bio-products production of plant-origin, and t he prospects. (authors)

  13. Engineering of systems for application of scientific computing in industry

    OpenAIRE

    Loeve, W.; Loeve, W.

    1992-01-01

    Mathematics software is of growing importance for computer simulation in industrial computer aided engineering. To be applicable in industry the mathematics software and supporting software must be structured in such a way that functions and performance can be maintained easily. In the present paper a method is described for development of mathematics software in such a way that this requirement can be met.

  14. Development of Desktop Computing Applications and Engineering Tools on GPUs

    DEFF Research Database (Denmark)

    Sørensen, Hans Henrik Brandenborg; Glimberg, Stefan Lemvig; Hansen, Toke Jansen

    (GPUs) for high-performance computing applications and software tools in science and engineering, inverse problems, visualization, imaging, dynamic optimization. The goals are to contribute to the development of new state-of-the-art mathematical models and algorithms for maximum throughout performance...

  15. Lot-sizing algorithms with applications to engineering and economics

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui; Ferreira, Jose S.

    1984-01-01

    of time-varying parameters. A comparison of the efficiency of the new solution procedures with well-known methods is developed. New applications of the techniques described within the fields of engineering (optimal design of a pump-pipe system) and economics (a model for import-planning) are referred to...

  16. Engineered Metallic Nanostructures: Fabrication, Characterization, and Applications

    Science.gov (United States)

    Bohloul, Arash

    Metallic nanostructures have garnered a great deal of attention due to their fascinating optical properties, which differ from the bulk metal. They have been proven to exceed expectations in wide variety of applications including chemical and biological sensing. Nevertheless, high-throughput and low cost nanofabrication techniques are required to implant metallic nanostructures in widespread applications. With that vision, this thesis presents a versatile and reliable method for scalable fabrication of gold nanostructures. In this approach, a plasma-treated ordered array of polystyrene nanospheres acts as an initial mask. The key step in this process is the vapor-deposition of nickel as a sacrificial mask. Thereby, gold nanostructures are directly formed on the substrate through the nickel mask. This is an easy, powerful, and straightforward method that offers several degrees of freedom to precisely control the shape and size of nanostructures. We made a library of nanostructures including gold nanocrescents, double crescents, nanorings, and nanodisks with the ability to tune the size in the range of 150 to 650 nm. The fabricated nanostructures are highly packed and uniformly cover the centimeter scale substrate. The optical properties of metallic nanostructures were extensively studied by a combination of UV-Vis-NIR and Fourier transform infrared (FTIR) spectroscopies, and correlation between optical response and geometrical parameters were investigated. In the next part of this thesis, highly sensitive surface enhanced infrared absorption (SEIRA) analysis was demonstrated on gold nanocrescent arrays. Theoretical modeling was confirmed that these substrates provide highly dense and strong hot-spots over the substrate, which is required for surface enhanced spectroscopic studies. Gold nanocrescent arrays exhibit highly tunable plasmon resonance to cover desired molecular vibrational bands. These substrates experimentally illustrated 3 orders of magnitude

  17. Dynamic social community detection and its applications.

    Directory of Open Access Journals (Sweden)

    Nam P Nguyen

    Full Text Available Community structure is one of the most commonly observed features of Online Social Networks (OSNs in reality. The knowledge of this feature is of great advantage: it not only provides helpful insights into developing more efficient social-aware solutions but also promises a wide range of applications enabled by social and mobile networking, such as routing strategies in Mobile Ad Hoc Networks (MANETs and worm containment in OSNs. Unfortunately, understanding this structure is very challenging, especially in dynamic social networks where social interactions are evolving rapidly. Our work focuses on the following questions: How can we efficiently identify communities in dynamic social networks? How can we adaptively update the network community structure based on its history instead of recomputing from scratch? To this end, we present Quick Community Adaptation (QCA, an adaptive modularity-based framework for not only discovering but also tracing the evolution of network communities in dynamic OSNs. QCA is very fast and efficient in the sense that it adaptively updates and discovers the new community structure based on its history together with the network changes only. This flexible approach makes QCA an ideal framework applicable for analyzing large-scale dynamic social networks due to its lightweight computing-resource requirement. To illustrate the effectiveness of our framework, we extensively test QCA on both synthesized and real-world social networks including Enron, arXiv e-print citation, and Facebook networks. Finally, we demonstrate the applicability of QCA in real applications: (1 A social-aware message forwarding strategy in MANETs, and (2 worm propagation containment in OSNs. Competitive results in comparison with other methods reveal that social-based techniques employing QCA as a community detection core outperform current available methods.

  18. Dynamic social community detection and its applications.

    Science.gov (United States)

    Nguyen, Nam P; Dinh, Thang N; Shen, Yilin; Thai, My T

    2014-01-01

    Community structure is one of the most commonly observed features of Online Social Networks (OSNs) in reality. The knowledge of this feature is of great advantage: it not only provides helpful insights into developing more efficient social-aware solutions but also promises a wide range of applications enabled by social and mobile networking, such as routing strategies in Mobile Ad Hoc Networks (MANETs) and worm containment in OSNs. Unfortunately, understanding this structure is very challenging, especially in dynamic social networks where social interactions are evolving rapidly. Our work focuses on the following questions: How can we efficiently identify communities in dynamic social networks? How can we adaptively update the network community structure based on its history instead of recomputing from scratch? To this end, we present Quick Community Adaptation (QCA), an adaptive modularity-based framework for not only discovering but also tracing the evolution of network communities in dynamic OSNs. QCA is very fast and efficient in the sense that it adaptively updates and discovers the new community structure based on its history together with the network changes only. This flexible approach makes QCA an ideal framework applicable for analyzing large-scale dynamic social networks due to its lightweight computing-resource requirement. To illustrate the effectiveness of our framework, we extensively test QCA on both synthesized and real-world social networks including Enron, arXiv e-print citation, and Facebook networks. Finally, we demonstrate the applicability of QCA in real applications: (1) A social-aware message forwarding strategy in MANETs, and (2) worm propagation containment in OSNs. Competitive results in comparison with other methods reveal that social-based techniques employing QCA as a community detection core outperform current available methods.

  19. Sandia technology: Engineering and science applications

    Science.gov (United States)

    Maydew, M. C.; Parrot, H.; Dale, B. C.; Floyd, H. L.; Leonard, J. A.; Parrot, L.

    1990-12-01

    This report discusses: protecting environment, safety, and health; Sandia's quality initiative; Sandia vigorously pursues technology transfer; scientific and technical education support programs; nuclear weapons development; recognizing battlefield targets with trained artificial neural networks; battlefield robotics: warfare at a distance; a spinning shell sizes up the enemy; thwarting would-be nuclear terrorists; unattended video surveillance system for nuclear facilities; making the skies safer for travelers; onboard instrumentation system to evaluate performance of stockpile bombs; keeping track with lasers; extended-life lithium batteries; a remote digital video link acquires images securely; guiding high-performance missiles with laser gyroscopes; nonvolatile memory chips for space applications; initiating weapon explosives with lasers; next-generation optoelectronics and microelectronics technology developments; chemometrics: new methods for improving chemical analysis; research team focuses ion beam to record-breaking intensities; standardizing the volt to quantum accuracy; new techniques improve robotic software development productivity; a practical laser plasma source for generating soft x-rays; exploring metal grain boundaries; massively parallel computing; modeling the amount of desiccant needed for moisture control; attacking pollution with sunshine; designing fuel-conversion catalysts with computers; extending a nuclear power plant's useful life; plasma-facing components for the International Thermonuclear Experimental Reactor.

  20. Generating Southern Africa Precipitation Forecast Using the FEWS Engine, a New Application for the Google Earth Engine

    Science.gov (United States)

    Landsfeld, M. F.; Hegewisch, K.; Daudert, B.; Morton, C.; Husak, G. J.; Friedrichs, M.; Funk, C. C.; Huntington, J. L.; Abatzoglou, J. T.; Verdin, J. P.

    2016-12-01

    The Famine Early Warning Systems Network (FEWS NET) focuses on food insecurity in developing nations and provides objective, evidence-based analysis to help government decision-makers and relief agencies plan for and respond to humanitarian emergencies. The network of FEWS NET analysts and scientists require flexible, interactive tools to aid in their monitoring and research efforts. Because they often work in bandwidth-limited regions, lightweight Internet tools and services that bypass the need for downloading massive datasets are preferred for their work. To support food security analysis FEWS NET developed a custom interface for the Google Earth Engine (GEE). GEE is a platform developed by Google to support scientific analysis of environmental data in their cloud computing environment. This platform allows scientists and independent researchers to mine massive collections of environmental data, leveraging Google's vast computational resources for purposes of detecting changes and monitoring the Earth's surface and climate. GEE hosts an enormous amount of satellite imagery and climate archives, one of which is the Climate Hazards Group Infrared Precipitation with Stations dataset (CHIRPS). CHIRPS precipitation dataset is a key input for FEWS NET monitoring and forecasting efforts. In this talk we introduce the FEWS Engine interface. We present an application that highlights the utility of FEWS Engine for forecasting the upcoming seasonal precipitation of southern Africa. Specifically, the current state of ENSO is assessed and used to identify similar historical seasons. The FEWS Engine compositing tool is used to examine rainfall and other environmental data for these analog seasons. The application illustrates the unique benefits of using FEWS Engine for on-the-fly food security scenario development.

  1. Transcription control engineering and applications in synthetic biology

    Directory of Open Access Journals (Sweden)

    Michael D. Engstrom

    2017-09-01

    Full Text Available In synthetic biology, researchers assemble biological components in new ways to produce systems with practical applications. One of these practical applications is control of the flow of genetic information (from nucleic acid to protein, a.k.a. gene regulation. Regulation is critical for optimizing protein (and therefore activity levels and the subsequent levels of metabolites and other cellular properties. The central dogma of molecular biology posits that information flow commences with transcription, and accordingly, regulatory tools targeting transcription have received the most attention in synthetic biology. In this mini-review, we highlight many past successes and summarize the lessons learned in developing tools for controlling transcription. In particular, we focus on engineering studies where promoters and transcription terminators (cis-factors were directly engineered and/or isolated from DNA libraries. We also review several well-characterized transcription regulators (trans-factors, giving examples of how cis- and trans-acting factors have been combined to create digital and analogue switches for regulating transcription in response to various signals. Last, we provide examples of how engineered transcription control systems have been used in metabolic engineering and more complicated genetic circuits. While most of our mini-review focuses on the well-characterized bacterium Escherichia coli, we also provide several examples of the use of transcription control engineering in non-model organisms. Similar approaches have been applied outside the bacterial kingdom indicating that the lessons learned from bacterial studies may be generalized for other organisms.

  2. Transcription control engineering and applications in synthetic biology.

    Science.gov (United States)

    Engstrom, Michael D; Pfleger, Brian F

    2017-09-01

    In synthetic biology, researchers assemble biological components in new ways to produce systems with practical applications. One of these practical applications is control of the flow of genetic information (from nucleic acid to protein), a.k.a. gene regulation. Regulation is critical for optimizing protein (and therefore activity) levels and the subsequent levels of metabolites and other cellular properties. The central dogma of molecular biology posits that information flow commences with transcription, and accordingly, regulatory tools targeting transcription have received the most attention in synthetic biology. In this mini-review, we highlight many past successes and summarize the lessons learned in developing tools for controlling transcription. In particular, we focus on engineering studies where promoters and transcription terminators ( cis -factors) were directly engineered and/or isolated from DNA libraries. We also review several well-characterized transcription regulators ( trans- factors), giving examples of how cis- and trans -acting factors have been combined to create digital and analogue switches for regulating transcription in response to various signals. Last, we provide examples of how engineered transcription control systems have been used in metabolic engineering and more complicated genetic circuits. While most of our mini-review focuses on the well-characterized bacterium Escherichia coli , we also provide several examples of the use of transcription control engineering in non-model organisms. Similar approaches have been applied outside the bacterial kingdom indicating that the lessons learned from bacterial studies may be generalized for other organisms.

  3. Applications of synchrotron radiation to Chemical Engineering Science: Workshop report

    International Nuclear Information System (INIS)

    1991-07-01

    This report contains extended abstracts that summarize presentations made at the Workshop on Applications of Synchrotron Radiation to Chemical Engineering Science held at Argonne National Laboratory (ANL), Argonne, IL, on April 22--23, 1991. The talks emphasized the application of techniques involving absorption fluorescence, diffraction, and reflection of synchrotron x-rays, with a focus on problems in applied chemistry and chemical engineering, as well as on the use of x-rays in topographic, tomographic, and lithographic procedures. The attendees at the workshop included experts in the field of synchrotron science, scientists and engineers from ANL, other national laboratories, industry, and universities; and graduate and undergraduate students who were enrolled in ANL educational programs at the time of the workshop. Talks in the Plenary and Overview Session described the status of and special capabilities to be offered by the Advanced Photon Source (APS), as well as strategies and opportunities for utilization of synchrotron radiation to solve science and engineering problems. Invited talks given in subsequent sessions covered the use of intense infrared, ultraviolet, and x-ray photon beams (as provided by synchrotrons) in traditional and nontraditional areas of chemical engineering research related to electrochemical and corrosion science, catalyst development and characterization, lithography and imaging techniques, and microanalysis

  4. Applications of synchrotron radiation to Chemical Engineering Science: Workshop report

    Energy Technology Data Exchange (ETDEWEB)

    1991-07-01

    This report contains extended abstracts that summarize presentations made at the Workshop on Applications of Synchrotron Radiation to Chemical Engineering Science held at Argonne National Laboratory (ANL), Argonne, IL, on April 22--23, 1991. The talks emphasized the application of techniques involving absorption fluorescence, diffraction, and reflection of synchrotron x-rays, with a focus on problems in applied chemistry and chemical engineering, as well as on the use of x-rays in topographic, tomographic, and lithographic procedures. The attendees at the workshop included experts in the field of synchrotron science, scientists and engineers from ANL, other national laboratories, industry, and universities; and graduate and undergraduate students who were enrolled in ANL educational programs at the time of the workshop. Talks in the Plenary and Overview Session described the status of and special capabilities to be offered by the Advanced Photon Source (APS), as well as strategies and opportunities for utilization of synchrotron radiation to solve science and engineering problems. Invited talks given in subsequent sessions covered the use of intense infrared, ultraviolet, and x-ray photon beams (as provided by synchrotrons) in traditional and nontraditional areas of chemical engineering research related to electrochemical and corrosion science, catalyst development and characterization, lithography and imaging techniques, and microanalysis.

  5. Risk reduction using DDP (Defect Detection and Prevention): Software support and software applications

    Science.gov (United States)

    Feather, M. S.

    2001-01-01

    Risk assessment and mitigation is the focus of the Defect Detection and Prevention (DDP) process, which has been applied to spacecraft technology assessments and planning, both hardware and software. DDP's major elements and their relevance to core requirement engineering concerns are summarized. The accompanying research demonstration illustrates DDP's tool support, and further customizations for application to software.

  6. 3D-Printed Biopolymers for Tissue Engineering Application

    Directory of Open Access Journals (Sweden)

    Xiaoming Li

    2014-01-01

    Full Text Available 3D printing technology has recently gained substantial interest for potential applications in tissue engineering due to the ability of making a three-dimensional object of virtually any shape from a digital model. 3D-printed biopolymers, which combine the 3D printing technology and biopolymers, have shown great potential in tissue engineering applications and are receiving significant attention, which has resulted in the development of numerous research programs regarding the material systems which are available for 3D printing. This review focuses on recent advances in the development of biopolymer materials, including natural biopolymer-based materials and synthetic biopolymer-based materials prepared using 3D printing technology, and some future challenges and applications of this technology are discussed.

  7. Micro-/nano-engineered cellular responses for soft tissue engineering and biomedical applications.

    Science.gov (United States)

    Tay, Chor Yong; Irvine, Scott Alexander; Boey, Freddy Y C; Tan, Lay Poh; Venkatraman, Subbu

    2011-05-23

    The development of biomedical devices and reconstruction of functional ex vivo tissues often requires the need to fabricate biomimetic surfaces with features of sub-micrometer precision. This can be achieved with the advancements in micro-/nano-engineering techniques, allowing researchers to manipulate a plethora of cellular behaviors at the cell-biomaterial interface. Systematic studies conducted on these 2D engineered surfaces have unraveled numerous novel findings that can potentially be integrated as part of the design consideration for future 2D and 3D biomaterials and will no doubt greatly benefit tissue engineering. In this review, recent developments detailing the use of micro-/nano-engineering techniques to direct cellular orientation and function pertinent to soft tissue engineering will be highlighted. Particularly, this article aims to provide valuable insights into distinctive cell interactions and reactions to controlled surfaces, which can be exploited to understand the mechanisms of cell growth on micro-/nano-engineered interfaces, and to harness this knowledge to optimize the performance of 3D artificial soft tissue grafts and biomedical applications. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  8. Recent applications of synthetic biology tools for yeast metabolic engineering

    DEFF Research Database (Denmark)

    Jensen, Michael Krogh; Keasling, Jay

    2015-01-01

    to engineer microbial chemical factories has steadily decreased, improvement is still needed. Through the development of synthetic biology tools for key microbial hosts, it should be possible to further decrease the development times and improve the reliability of the resulting microorganism. Together...... with continuous decreases in price and improvements in DNA synthesis, assembly and sequencing, synthetic biology tools will rationalize time-consuming strain engineering, improve control of metabolic fluxes, and diversify screening assays for cellular metabolism. This review outlines some recently developed...... synthetic biology tools and their application to improve production of chemicals and fuels in yeast. Finally, we provide a perspective for the challenges that lie ahead....

  9. Introduction to the application of genetic algorithms in engineering

    Directory of Open Access Journals (Sweden)

    I. S. Shaw

    1998-07-01

    Full Text Available Genetic algorithms constitute a new research area in the field of artificial intelligence. This work is aimed at their application in specific areas of engineering where good results have already been achieved. The purpose of this work is to provide a basic introduction for students as well as experienced engineers who wish to upgrade their knowledge. A distinctive feature of artificial intelligence is that instead of mathematical models, either direct human experience or certain functions of the human brain for the modelling of physical phenomena are used.

  10. Advanced FDTD methods parallelization, acceleration, and engineering applications

    CERN Document Server

    Yu, Wenhua

    2011-01-01

    The finite-difference time-domain (FDTD) method has revolutionized antenna design and electromagnetics engineering. Here's a cutting-edge book that focuses on the performance optimization and engineering applications of FDTD simulation systems. Covering the latest developments in this area, this unique resource offer you expert advice on the FDTD method, hardware platforms, and network systems. Moreover the book offers guidance in distinguishing between the many different electromagnetics software packages on the market today. You also find a complete chapter dedicated to large multi-scale pro

  11. Probability with applications to investments, insurance, and engineering

    CERN Document Server

    Bean, Michael A

    2009-01-01

    This book covers the basic probability of distributions with an emphasis on applications from the areas of investments, insurance, and engineering. Written by a Fellow of the Casualty Actuarial Society and the Society of Actuaries with many years of experience as a university professor and industry practitioner, the book is suitable as a text for senior undergraduate and beginning graduate students in mathematics, statistics, actuarial science, finance, or engineering as well as a reference for practitioners in these fields. The book is particularly well suited for students preparing for profe

  12. Computer, Network, Software, and Hardware Engineering with Applications

    CERN Document Server

    Schneidewind, Norman F

    2012-01-01

    There are many books on computers, networks, and software engineering but none that integrate the three with applications. Integration is important because, increasingly, software dominates the performance, reliability, maintainability, and availability of complex computer and systems. Books on software engineering typically portray software as if it exists in a vacuum with no relationship to the wider system. This is wrong because a system is more than software. It is comprised of people, organizations, processes, hardware, and software. All of these components must be considered in an integr

  13. Engineering applications of discrete-time optimal control

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui; Ravn, Hans V.

    1990-01-01

    Many problems of design and operation of engineering systems can be formulated as optimal control problems where time has been discretisized. This is also true even if 'time' is not involved in the formulation of the problem, but rather another one-dimensional parameter. This paper gives a review...... of some well-known and new results in discrete time optimal control methods applicable to practical problem solving within engineering. Emphasis is placed on dynamic programming, the classical maximum principle and generalized versions of the maximum principle for optimal control of discrete time systems...

  14. Ice Engineering. Number 25, September 2000. Remote Ice Motion Detection

    National Research Council Canada - National Science Library

    2000-01-01

    .... Government agencies, and the engineering community in general. The potential exists for property damage, serious injury, and fatalities during ice-related flooding, evacuations, and other ice mitigation operations...

  15. Engineering Rugged Field Assays to Detect Hazardous Chemicals Using Spore-Based Bacterial Biosensors.

    Science.gov (United States)

    Wynn, Daniel; Deo, Sapna; Daunert, Sylvia

    2017-01-01

    Bacterial whole cell-based biosensors have been genetically engineered to achieve selective and reliable detection of a wide range of hazardous chemicals. Although whole-cell biosensors demonstrate many advantages for field-based detection of target analytes, there are still some challenges that need to be addressed. Most notably, their often modest shelf life and need for special handling and storage make them challenging to use in situations where access to reagents, instrumentation, and expertise are limited. These problems can be circumvented by developing biosensors in Bacillus spores, which can be engineered to address all of these concerns. In its sporulated state, a whole cell-based biosensor has a remarkably long life span and is exceptionally resistant to environmental insult. When these spores are germinated for use in analytical techniques, they show no loss in performance, even after long periods of storage under harsh conditions. In this chapter, we will discuss the development and use of whole cell-based sensors, their adaptation to spore-based biosensors, their current applications, and future directions in the field. © 2017 Elsevier Inc. All rights reserved.

  16. 76 FR 37085 - Applications for New Awards; Rehabilitation Engineering Research Centers (RERCs)

    Science.gov (United States)

    2011-06-24

    ... DEPARTMENT OF EDUCATION Applications for New Awards; Rehabilitation Engineering Research Centers...)--Disability and Rehabilitation Research Projects and Centers Program--Rehabilitation Engineering Research... (Rehabilitation Act). Rehabilitation Engineering Research Centers Program (RERCs) The purpose of the RERC program...

  17. Metabolic engineering of Yarrowia lipolytica for industrial applications.

    Science.gov (United States)

    Zhu, Quinn; Jackson, Ethel N

    2015-12-01

    Yarrowia lipolytica is a safe and robust yeast that has a history of industrial applications. Its physiological, metabolic and genomic characteristics have made it a superior host for metabolic engineering. The results of optimizing internal pathways and introducing new pathways have demonstrated that Y. lipolytica can be a platform cell factory for cost-effective production of chemicals and fuels derived from fatty acids, lipids and acetyl-CoA. Two products have been commercialized from metabolically engineered Y. lipolytica strains producing high amounts of omega-3 eicosapentaenoic acid, and more products are on the way to be produced at industrial scale. Here we review recent progress in metabolic engineering of Y. lipolytica for production of biodiesel fuel, functional fatty acids and carotenoids. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  18. Selected engineering properties and applications of EPS geofoam

    Science.gov (United States)

    Elragi, Ahmed Fouad

    Expanded polystyrene (EPS) geofoam is a lightweight material that has been used in engineering applications since at least the 1950s. Its density is about a hundredth of that of soil. It has good thermal insulation properties with stiffness and compression strength comparable to medium clay. It is utilized in reducing settlement below embankments, sound and vibration damping, reducing lateral pressure on substructures, reducing stresses on rigid buried conduits and related applications. This study starts with an overview on EPS geofoam. EPS manufacturing processes are described followed by a review of engineering properties found in previous research work done so far. Standards and design manuals applicable to EPS are presented. Selected EPS geofoam-engineering applications are discussed with examples. State-of-the-art of experimental work is done on different sizes of EPS specimens under different loading rates for better understanding of the behavior of the material. The effects of creep, sample size, strain rate and cyclic loading on the stress strain response are studied. Equations for the initial modulus and the strength of the material under compression for different strain rates are presented. The initial modulus and Poisson's ratio are discussed in detail. Sample size effect on creep behavior is examined. Three EPS projects are shown in this study. The creep behavior of the largest EPS geofoam embankment fill is shown. Results from laboratory tests, mathematical modeling and field records are compared to each other. Field records of a geofoam-stabilized slope are compared to finite difference analysis results. Lateral stress reduction on an EPS backfill retaining structure is analyzed. The study ends with a discussion on two promising properties of EPS geofoam. These are the damping ability and the compressibility of this material. Finite element analysis, finite difference analysis and lab results are included in this discussion. The discussion with the

  19. The Application of Biomedical Engineering Techniques to the Diagnosis and Management of Tropical Diseases: A Review

    Directory of Open Access Journals (Sweden)

    Fatimah Ibrahim

    2015-03-01

    Full Text Available This paper reviews a number of biomedical engineering approaches to help aid in the detection and treatment of tropical diseases such as dengue, malaria, cholera, schistosomiasis, lymphatic filariasis, ebola, leprosy, leishmaniasis, and American trypanosomiasis (Chagas. Many different forms of non-invasive approaches such as ultrasound, echocardiography and electrocardiography, bioelectrical impedance, optical detection, simplified and rapid serological tests such as lab-on-chip and micro-/nano-fluidic platforms and medical support systems such as artificial intelligence clinical support systems are discussed. The paper also reviewed the novel clinical diagnosis and management systems using artificial intelligence and bioelectrical impedance techniques for dengue clinical applications.

  20. The application of biomedical engineering techniques to the diagnosis and management of tropical diseases: a review.

    Science.gov (United States)

    Ibrahim, Fatimah; Thio, Tzer Hwai Gilbert; Faisal, Tarig; Neuman, Michael

    2015-03-23

    This paper reviews a number of biomedical engineering approaches to help aid in the detection and treatment of tropical diseases such as dengue, malaria, cholera, schistosomiasis, lymphatic filariasis, ebola, leprosy, leishmaniasis, and American trypanosomiasis (Chagas). Many different forms of non-invasive approaches such as ultrasound, echocardiography and electrocardiography, bioelectrical impedance, optical detection, simplified and rapid serological tests such as lab-on-chip and micro-/nano-fluidic platforms and medical support systems such as artificial intelligence clinical support systems are discussed. The paper also reviewed the novel clinical diagnosis and management systems using artificial intelligence and bioelectrical impedance techniques for dengue clinical applications.

  1. Rapid prototyping technology and its application in bone tissue engineering.

    Science.gov (United States)

    Yuan, Bo; Zhou, Sheng-Yuan; Chen, Xiong-Sheng

    Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies. This review focuses on the basic principles and characteristics of various fabrication technologies, such as stereolithography, selective laser sintering, and fused deposition modeling, and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering. In the near future, the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects.

  2. Rapid prototyping technology and its application in bone tissue engineering*

    Science.gov (United States)

    YUAN, Bo; ZHOU, Sheng-yuan; CHEN, Xiong-sheng

    2017-01-01

    Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies. This review focuses on the basic principles and characteristics of various fabrication technologies, such as stereolithography, selective laser sintering, and fused deposition modeling, and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering. In the near future, the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects. PMID:28378568

  3. GLobal Integrated Design Environment (GLIDE): A Concurrent Engineering Application

    Science.gov (United States)

    McGuire, Melissa L.; Kunkel, Matthew R.; Smith, David A.

    2010-01-01

    The GLobal Integrated Design Environment (GLIDE) is a client-server software application purpose-built to mitigate issues associated with real time data sharing in concurrent engineering environments and to facilitate discipline-to-discipline interaction between multiple engineers and researchers. GLIDE is implemented in multiple programming languages utilizing standardized web protocols to enable secure parameter data sharing between engineers and researchers across the Internet in closed and/or widely distributed working environments. A well defined, HyperText Transfer Protocol (HTTP) based Application Programming Interface (API) to the GLIDE client/server environment enables users to interact with GLIDE, and each other, within common and familiar tools. One such common tool, Microsoft Excel (Microsoft Corporation), paired with its add-in API for GLIDE, is discussed in this paper. The top-level examples given demonstrate how this interface improves the efficiency of the design process of a concurrent engineering study while reducing potential errors associated with manually sharing information between study participants.

  4. Biocompatibility of hydrogel-based scaffolds for tissue engineering applications.

    Science.gov (United States)

    Naahidi, Sheva; Jafari, Mousa; Logan, Megan; Wang, Yujie; Yuan, Yongfang; Bae, Hojae; Dixon, Brian; Chen, P

    2017-09-01

    Recently, understanding of the extracellular matrix (ECM) has expanded rapidly due to the accessibility of cellular and molecular techniques and the growing potential and value for hydrogels in tissue engineering. The fabrication of hydrogel-based cellular scaffolds for the generation of bioengineered tissues has been based on knowledge of the composition and structure of ECM. Attempts at recreating ECM have used either naturally-derived ECM components or synthetic polymers with structural integrity derived from hydrogels. Due to their increasing use, their biocompatibility has been questioned since the use of these biomaterials needs to be effective and safe. It is not surprising then that the evaluation of biocompatibility of these types of biomaterials for regenerative and tissue engineering applications has been expanded from being primarily investigated in a laboratory setting to being applied in the multi-billion dollar medicinal industry. This review will aid in the improvement of design of non-invasive, smart hydrogels that can be utilized for tissue engineering and other biomedical applications. In this review, the biocompatibility of hydrogels and design criteria for fabricating effective scaffolds are examined. Examples of natural and synthetic hydrogels, their biocompatibility and use in tissue engineering are discussed. The merits and clinical complications of hydrogel scaffold use are also reviewed. The article concludes with a future outlook of the field of biocompatibility within the context of hydrogel-based scaffolds. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Flavonoid engineering of flax potentiate its biotechnological application

    Directory of Open Access Journals (Sweden)

    Prescha Anna

    2011-01-01

    Full Text Available Abstract Background Flavonoids are a group of secondary plant metabolites important for plant growth and development. They show also a protective effect against colon and breast cancer, diabetes, hypercholesterolemic atherosclerosis, lupus nephritis, and immune and inflammatory reactions. Thus, overproduction of these compounds in flax by genetic engineering method might potentiate biotechnological application of these plant products. Results Flax plants of third generation overexpressing key genes of flavonoid pathway cultivated in field were used as plant material throughout this study. The biochemical properties of seed, oil and seedcake extracts and fibre from natural and transgenic flax plants were compared. The data obtained suggests that the introduced genes were stably inherited and expressed through plant generations. Overproduction of flavonoid compounds resulted in increase of fatty acids accumulation in oil from transgenic seeds due to protection from oxidation offered during synthesis and seed maturation. The biochemical analysis of seedcake extracts from seeds of transgenic flax revealed significant increase in flavonoids (kaempferol, phenolic acids (coumaric, ferulic, synapic acids and lignan content. Fibres, another product of flax plant showed increase in the level of catechine and acetylvanillone and decrease in phenolic acids upon flax modification. Biochemical analysis results were confirmed using IR spectroscopy. The integral intensities of IR bands have been used for identification of the component of phenylpropanoid pathway in oil, seedcake extract and fibre from control and transgenic flax. It was shown that levels of flavonoids, phenolic acids and lignans in oil and seedcake extract was higher in transgenic flax products compared to control. An FT-IR study of fibres confirmed the biochemical data and revealed that the arrangement of the cellulose polymer in the transgenic fibres differs from the control; in particular a

  6. The development and application of engineered proteins for bioremediation

    Energy Technology Data Exchange (ETDEWEB)

    Trewhella, J. [ed.

    1995-09-26

    Clean up of the toxic legacy of the Cold War is projected to be the most expensive domestic project the nation has yet undertaken. Remediation of the Department of Energy and Department of Defense toxic waste sites alone are projected to cost {approximately}$1 trillion over a 20-30 year period. New, cost effective technologies are needed to attack this enormous problem. Los Alamos has put together a cross-divisional team of scientist to develop science based bioremediation technology to work toward this goal. In the team we have expertise in: (1) molecular, ecosystem and transport modeling; (2) genetic and protein engineering; (3) microbiology and microbial ecology; (4) structural biology; and (5) bioinorganic chemistry. This document summarizes talks at a workshop of different aspects of bioremediation technology including the following: Introducing novel function into a Heme enzyme: engineering by excavation; cytochrome P-450: ideal systems for bioremediation?; selection and development of bacterial strains for in situ remediation of cholorinated solvents; genetic analysis and preparation of toluene ortho-monooxygenase for field application in remediation of trichloroethylene; microbial ecology and diversity important to bioremediation; engineering haloalkane dehalogenase for bioremediation; enzymes for oxidative biodegradation; indigenous bacteria as hosts for engineered proteins; performance of indigenous bacterial, hosting engineered proteins in microbial communities.

  7. Piezoelectric polymers as biomaterials for tissue engineering applications.

    Science.gov (United States)

    Ribeiro, Clarisse; Sencadas, Vítor; Correia, Daniela M; Lanceros-Méndez, Senentxu

    2015-12-01

    Tissue engineering often rely on scaffolds for supporting cell differentiation and growth. Novel paradigms for tissue engineering include the need of active or smart scaffolds in order to properly regenerate specific tissues. In particular, as electrical and electromechanical clues are among the most relevant ones in determining tissue functionality in tissues such as muscle and bone, among others, electroactive materials and, in particular, piezoelectric ones, show strong potential for novel tissue engineering strategies, in particular taking also into account the existence of these phenomena within some specific tissues, indicating their requirement also during tissue regeneration. This referee reports on piezoelectric materials used for tissue engineering applications. The most used materials for tissue engineering strategies are reported together with the main achievements, challenges and future needs for research and actual therapies. This review provides thus a compilation of the most relevant results and strategies and a start point for novel research pathways in the most relevant and challenging open questions. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Sandia National Laboratories ASCI Applications Software Quality Engineering Practices; TOPICAL

    International Nuclear Information System (INIS)

    ZEPPER, JOHN D.; ARAGON, KATHRYN MARY; ELLIS, MOLLY A.; BYLE, KATHLEEN A.; EATON, DONNA SUE

    2002-01-01

    This document provides a guide to the deployment of the software verification activities, software engineering practices, and project management principles that guide the development of Accelerated Strategic Computing Initiative (ASCI) applications software at Sandia National Laboratories (Sandia). The goal of this document is to identify practices and activities that will foster the development of reliable and trusted products produced by the ASCI Applications program. Document contents include an explanation of the structure and purpose of the ASCI Quality Management Council, an overview of the software development lifecycle, an outline of the practices and activities that should be followed, and an assessment tool. These sections map practices and activities at Sandia to the ASCI Software Quality Engineering: Goals, Principles, and Guidelines, a Department of Energy document

  9. Catastrophe theory and its application status in mechanical engineering

    Directory of Open Access Journals (Sweden)

    Jinge LIU

    Full Text Available Catastrophe theory is a kind of mathematical method which aims to apply and interpret the discontinuous phenomenon. Since its emergence, it has been widely used to explain a variety of emergent phenomena in the fields of natural science, social science, management science and some other science and technology fields. Firstly, this paper introduces the theory of catastrophe in several aspects, such as its generation, radical principle, basic characteristics and development. Secondly, it summarizes the main applications of catastrophe theory in the field of mechanical engineering, focusing on the research progress of catastrophe theory in revealing catastrophe of rotor vibration state, analyzing friction and wear failure, predicting metal fracture, and so on. Finally, it advises that later development of catastrophe theory should pay more attention to the combination of itself with other traditional nonlinear theories and methods. This paper provides a beneficial reference to guide the application of catastrophe theory in mechanical engineering and related fields for later research.

  10. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm

    2015-01-01

     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  11. Application of plasma technology to nuclear engineering fields

    International Nuclear Information System (INIS)

    Suzuki, Masaaki; Akatsuka, Hiroshi

    1996-01-01

    In order to discuss about the application of the plasma technology to nuclear engineering fields, we mention two subjects, the oxygenation of metal chloride waste by oxygen plasma and the characterization of fine particles generated in the plasma process. Through the experimental results of two subjects, both of the advantage and the disadvantage of the plasma technology and their characteristics are shown and discussed. The following conclusions are obtained. The reactive plasma is effective to oxygenate the chloride wastes. The particle generation which is one of the disadvantages must not be specialized and its characteristics can be estimated. Consequently, the plasma technology should be applicable to nuclear engineering fields adopting its advantage and overcoming its disadvantage. (author)

  12. [Flexible print circuit technology application in biomedical engineering].

    Science.gov (United States)

    Jiang, Lihua; Cao, Yi; Zheng, Xiaolin

    2013-06-01

    Flexible print circuit (FPC) technology has been widely applied in variety of electric circuits with high precision due to its advantages, such as low-cost, high specific fabrication ability, and good flexibility, etc. Recently, this technology has also been used in biomedical engineering, especially in the development of microfluidic chip and microelectrode array. The high specific fabrication can help making microelectrode and other micro-structure equipment. And good flexibility allows the micro devices based on FPC technique to be easily packaged with other parts. In addition, it also reduces the damage of microelectrodes to the tissue. In this paper, the application of FPC technology in biomedical engineering is introduced. Moreover, the important parameters of FPC technique and the development trend of prosperous applications is also discussed.

  13. Fuzzy commutative algebra and its application in mechanical engineering

    International Nuclear Information System (INIS)

    Han, J.; Song, H.

    1996-01-01

    Based on literature data, this paper discusses the whole mathematical structure about point-fuzzy number set F(R). By introducing some new operations about addition, subtraction, multiplication, division and scalar multiplication, we prove that F(R) can form fuzzy linear space, fuzzy commutative ring, fuzzy commutative algebra in order. Furthermore, we get that A is fuzzy commutative algebra for any fuzzy subset. At last, we give an application of point-fuzzy number to mechanical engineering

  14. Chaos in neurons and its application: perspective of chaos engineering.

    Science.gov (United States)

    Hirata, Yoshito; Oku, Makito; Aihara, Kazuyuki

    2012-12-01

    We review our recent work on chaos in neurons and its application to neural networks from perspective of chaos engineering. Especially, we analyze a dataset of a squid giant axon by newly combining our previous work of identifying Devaney's chaos with surrogate data analysis, and show that an axon can behave chaotically. Based on this knowledge, we use a chaotic neuron model to investigate possible information processing in the brain.

  15. Strain Engineering for Phosphorene: The Potential Application as a Photocatalyst

    OpenAIRE

    Sa, Baisheng; Li, Yan-Ling; Qi, Jingshan; Ahuja, Rajeev; Sun, Zhimei

    2014-01-01

    Phosphorene has been attracted intense interest due to its unexpected high carrier mobility and distinguished anisotropic optoelectronic and electronic properties. In this work, we unraveled strain engineered phosphorene as a photocatalyst in the application of water splitting hydrogen production based on density functional theory calculations. Lattice dynamic calculations demonstrated the stability for such kind of artificial materials under different strains. The phosphorene lattice is unst...

  16. Molecular profiling techniques as tools to detect potential unintended effects in genetically engineered maize

    CSIR Research Space (South Africa)

    Barros, E

    2010-05-01

    Full Text Available Molecular Profiling Techniques as Tools to Detect Potential Unintended Effects in Genetically Engineered Maize Eugenia Barros Introduction In the early stages of production and commercialization of foods derived from genetically engineered (GE) plants... systems. In a recent paper published in Plant Biotechnology Journal,4 we compared two transgenic white maize lines with the non-transgenic counterpart to investigate two possible sources of variation: genetic engineering and environmental variation...

  17. Real cases study through computer applications for futures Agricultural Engineers

    Science.gov (United States)

    Moratiel, R.; Durán, J. M.; Tarquis, A. M.

    2010-05-01

    One of the huge concerns on the higher engineer education is the lag of real cases study that the future professionals need in the work and corporation market. This concern was reflected in Bologna higher education system including recommendations in this respect. The knowhow as why this or other methodology is one of the keys to resolve this problem. In the last courses given in Department of Crop Production, at the Agronomy Engineer School of Madrid (Escuela Técnica Superior de Ingenieros Agrónomos, UPM) we have developed more than one hundred applications in Microsoft Excel®. Our aim was to show different real scenarios which the future Agronomic Engineers can be found in their professional life and with items related to crop production field. In order to achieve our target, each application in Excel presents a file text in which is explained the theoretical concepts and the objectives, as well as some resources used from Excel syntax. In this way, the student can understand and use of such application, even they can modify and customize it for a real case presented in their context and/or master project. This electronic monograph gives an answer to the need to manage data in several real scenarios showed in lectures, calculus resolution, information analysis and manage worksheets in a professional and student level.

  18. Orthogonal polarization in lasers physical phenomena and engineering applications

    CERN Document Server

    Zhang, Shulian

    2013-01-01

    This practical book summarizes the latest research results of orthogonally polarized lasers, birefringence laser cavities, and their applications. Coverage ranges from basic principles and technologies to the characteristics of different cavities and lasers to various measurement techniques. A number of figures, experimental designs, and measurement curves are included, helping readers gain a thorough understanding of the many applications in modern engineering and start their own projects. Many types of relevant lasers (Helium/Neon lasers, Nd:YAG lasers, laser diodes, etc.) are also discussed

  19. Applications of super - high intensity lasers in nuclear engineering

    International Nuclear Information System (INIS)

    Salomaa, R.; Hakola, A.; Santala, M.

    2007-01-01

    Laser-plasma interactions arising when a super intense ultrashort laser pulse impinges a solid target creates intense partly collimated and energy resolved photons, high energy electron and protons and neutrons. In addition the plasma plume can generate huge magnetic and electric fields. Also ultra short X-ray pulses are created. We have participated in some of such experiments at Rutherford and Max-Planck Institute and assessed the applications of such kind as laser-driven accelerators. This paper discusses applications in nuclear engineering (neutron sources, isotope separation, fast ignition and transmutation, etc). In particular the potential for extreme time resolution and to partial energy resolution are assessed

  20. Photonics applications and web engineering: WILGA Summer 2016

    Science.gov (United States)

    Romaniuk, Ryszard S.

    2016-09-01

    Wilga Summer 2016 Symposium on Photonics Applications and Web Engineering was held on 29 May - 06 June. The Symposium gathered over 350 participants, mainly young researchers active in optics, optoelectronics, photonics, electronics technologies and applications. There were presented around 300 presentations in a few main topical tracks including: bio-photonics, optical sensory networks, photonics-electronics-mechatronics co-design and integration, large functional system design and maintenance, Internet of Thins, and other. The paper is an introduction the 2016 WILGA Summer Symposium Proceedings, and digests some of the Symposium chosen key presentations.

  1. Generalized Linear Models with Applications in Engineering and the Sciences

    CERN Document Server

    Myers, Raymond H; Vining, G Geoffrey; Robinson, Timothy J

    2012-01-01

    Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities."-Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Ma

  2. Photonics applications and web engineering: WILGA Summer 2015

    Science.gov (United States)

    Romaniuk, Ryszard S.

    2015-09-01

    Wilga Summer 2015 Symposium on Photonics Applications and Web Engineering was held on 23-31 May. The Symposium gathered over 350 participants, mainly young researchers active in optics, optoelectronics, photonics, electronics technologies and applications. There were presented around 300 presentations in a few main topical tracks including: bio-photonics, optical sensory networks, photonics-electronics-mechatronics co-design and integration, large functional system design and maintenance, Internet of Thins, and other. The paper is an introduction the 2015 WILGA Summer Symposium Proceedings, and digests some of the Symposium chosen key presentations.

  3. Underlying finite state machine for the social engineering attack detection model

    CSIR Research Space (South Africa)

    Mouton, Francois

    2017-08-01

    Full Text Available one to have a clearer overview of the mental processing performed within the model. While the current model provides a general procedural template for implementing detection mechanisms for social engineering attacks, the finite state machine provides a...

  4. Application of carbon fiber reinforced carbon composite to nuclear engineering

    International Nuclear Information System (INIS)

    Ishihara, Masahiro

    2003-01-01

    Carbon fiber reinforced carbon matrix composite (C/C composite) is thought to be one of promising structural materials with high temperature resistivity in the nuclear engineering field. In the high temperature gas-cooled reactors with gas outlet temperature maximum around 1000degC, high performance core internal structures, such as control rod sheath, core restraint mechanism, will be expected to achieve by the C/C composite application. Moreover, in the fusion reactors, plasma facing structures having high temperature with high neutron irradiation and particle collision will be expected to achieve by the C/C composite application. In this paper, current research and development studies of the C/C composite application on both reactors are reviewed and vista of the future on the C/C composite application is mentioned. (author)

  5. Statistical Damage Detection of Civil Engineering Structures using ARMAV Models

    DEFF Research Database (Denmark)

    Andersen, P.; Kirkegaard, Poul Henning

    In this paper a statistically based damage detection of a lattice steel mast is performed. By estimation of the modal parameters and their uncertainties it is possible to detect whether some of the modal parameters have changed with a statistical significance. The estimation of the uncertainties ...

  6. Development and application of laser techniques for studying fuel dynamics and NO formation in engines

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Oeivind

    2000-11-01

    In this work a number of laser techniques have been applied in new ways for combustion diagnostics in engines. The applications cover small two-stroke engines, ordinary spark ignition (SI) engines, direct-injection spark ignition (DISI) engines, and heavy-duty diesel truck engines. In an investigation of unmodified two-stroke engines running at high engine speed, it has been shown that cycle-resolved laser diagnostics are applicable to real-world engines. The emission of unburned fuel was detected at the exhaust port with successful discrimination against other unburned hydrocarbons. Although a few problems remain to be solved in order to get quantitative concentration data, valuable information can nonetheless be attained using this technique. The technique would benefit from the use of a non-fluorescing lubricant, as that would decrease the background fluorescence. Laser-based techniques also provide a useful tool for studying the fuel dynamics inside the cylinder. In the development of DISI engines it is of particular importance to acquire knowledge about the distribution of fuel around the spark plug. Numerical computer codes are often used as design tools in these applications. Laser techniques are capable of yielding instantaneous multi-point concentration information with high spatial and temporal resolution, making them ideal both for validation of CFD simulations and for testing designs. The feasibility of using laser diagnostics in the development of DISI engines has been shown. Future research should be aimed at simplifying the procedure for quantifying the data, since a fairly simple and reliable technique would be an important asset for the industry. In a more fundamental study, it has been shown that it is possible to simultaneously detect a substance in both liquid and vapour phase. Water was used in the study since it is easily produced in both phases. Liquid drops were detected using spontaneous Raman scattering, whereas the vapour surrounding them

  7. Development and application of laser techniques for studying fuel dynamics and NO formation in engines

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Oeivind

    2000-11-01

    In this work a number of laser techniques have been applied in new ways for combustion diagnostics in engines. The applications cover small two-stroke engines, ordinary spark ignition (SI) engines, direct-injection spark ignition (DISI) engines, and heavy-duty diesel truck engines. In an investigation of unmodified two-stroke engines running at high engine speed, it has been shown that cycle-resolved laser diagnostics are applicable to real-world engines. The emission of unburned fuel was detected at the exhaust port with successful discrimination against other unburned hydrocarbons. Although a few problems remain to be solved in order to get quantitative concentration data, valuable information can nonetheless be attained using this technique. The technique would benefit from the use of a non-fluorescing lubricant, as that would decrease the background fluorescence. Laser-based techniques also provide a useful tool for studying the fuel dynamics inside the cylinder. In the development of DISI engines it is of particular importance to acquire knowledge about the distribution of fuel around the spark plug. Numerical computer codes are often used as design tools in these applications. Laser techniques are capable of yielding instantaneous multi-point concentration information with high spatial and temporal resolution, making them ideal both for validation of CFD simulations and for testing designs. The feasibility of using laser diagnostics in the development of DISI engines has been shown. Future research should be aimed at simplifying the procedure for quantifying the data, since a fairly simple and reliable technique would be an important asset for the industry. In a more fundamental study, it has been shown that it is possible to simultaneously detect a substance in both liquid and vapour phase. Water was used in the study since it is easily produced in both phases. Liquid drops were detected using spontaneous Raman scattering, whereas the vapour surrounding them

  8. Laser ultrasonics for civil engineering : some applications in development for concrete non destructive testing

    International Nuclear Information System (INIS)

    Abraham, O; Cottineau, L-M; Durand, O; Popovics, J S

    2011-01-01

    Non destructive testing of civil engineering infrastructures is becoming of primary importance for their diagnosis, residual time life estimation and/or structural health monitoring. A particularity of civil engineering application is the large size of the survey zones and the expected low cost of inspection. In this context non contact ultrasonics may offer the possibility to built robots that can automatically scan large areas (or eventually be integrated in moving vehicles) to recover mechanical properties of material or to perform imagery for geometrical information recovery. In this paper we present two possible applications of in situ laser ultrasonics : one is the detection of voids in tendon duct with the impact echo method, the other is the use of surface waves to recover mechanical properties of the first centimetres of concrete structures (here after called cover concrete).

  9. The System Concept and Its Application to Engineering

    CERN Document Server

    Aslaksen, Erik W

    2013-01-01

    Systems engineering is a mandatory approach in some industries, and is gaining wider acceptance for complex projects in general. However, under the imperative of delivering these projects on time and within budget, the focus has been mainly on the management aspects, with less attention to improving the core engineering activity – design. This book addresses the application of the system concept to design in several ways: by developing a deeper understanding of the system concept, by defining design and its characteristics within the process of engineering, and by applying the system concept to the early stage of design, where it has the greatest impact.   A central theme of the book is that the purpose of engineering is to be useful in meeting the needs of society, and that therefore the ultimate measure of the benefit of applying the system concept should be the extent to which it advances the achievement of that purpose. Consequently, any consistent, top-down development of the functionality required of...

  10. Trends in high power laser applications in civil engineering

    Science.gov (United States)

    Wignarajah, Sivakumaran; Sugimoto, Kenji; Nagai, Kaori

    2005-03-01

    This paper reviews the research and development efforts made on the use of lasers for material processing in the civil engineering industry. Initial investigations regarding the possibility of using lasers in civil engineering were made in the 1960s and '70s, the target being rock excavation. At that time however, the laser powers available were too small for any practical application utilization. In the 1980's, the technology of laser surface cleaning of historically important structures was developed in Europe. In the early 1990s, techniques of laser surface modification, including glazing and coloring of concrete, roughening of granite stones, carbonization of wood were pursued, mainly in Japan. In the latter part of the decade, techniques of laser decontamination of concrete surfaces in nuclear facilities were developed in many countries, and field tests were caried out in Japan. The rapid advances in development of diode lasers and YAG lasers with high power outputs and efficiencies since the late 1990's have led to a revival of worldwide interest in the use of lasers for material processing in civil engineering. The authors believe that, in the next 10 years or so, the advent of compact high power lasers is likely to lead to increased use of lasers of material processing in the field of civil engineering.

  11. Applications of computational modeling in metabolic engineering of yeast.

    Science.gov (United States)

    Kerkhoven, Eduard J; Lahtvee, Petri-Jaan; Nielsen, Jens

    2015-02-01

    Generally, a microorganism's phenotype can be described by its pattern of metabolic fluxes. Although fluxes cannot be measured directly, inference of fluxes is well established. In biotechnology the aim is often to increase the capacity of specific fluxes. For this, metabolic engineering methods have been developed and applied extensively. Many of these rely on balancing of intracellular metabolites, redox, and energy fluxes, using genome-scale models (GEMs) that in combination with appropriate objective functions and constraints can be used to predict potential gene targets for obtaining a preferred flux distribution. These methods point to strategies for altering gene expression; however, fluxes are often controlled by post-transcriptional events. Moreover, GEMs are usually not taking into account metabolic regulation, thermodynamics and enzyme kinetics. To facilitate metabolic engineering, tools from synthetic biology have emerged, enabling integration and assembly of naturally nonexistent, but well-characterized components into a living organism. To describe these systems kinetic models are often used and to integrate these systems with the standard metabolic engineering approach, it is necessary to expand the modeling of metabolism to consider kinetics of individual processes. This review will give an overview about models available for metabolic engineering of yeast and discusses their applications. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permission@oup.com.

  12. CRISPR Mediated Genome Engineering and its Application in Industry.

    Science.gov (United States)

    Kaboli, Saeed; Babazada, Hasan

    2018-01-01

    The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9 (CRISPR-associated nuclease 9) method has been dramatically changing the field of genome engineering. It is a rapid, highly efficient and versatile tool for precise modification of genome that uses a guide RNA (gRNA) to target Cas9 to a specific sequence. This novel RNA-guided genome-editing technique has become a revolutionary tool in biomedical science and has many innovative applications in different fields. In this review, we briefly introduce the Cas9-mediated genome-editing tool, summarize the recent advances in CRISPR/Cas9 technology to engineer the genomes of a wide variety of organisms, and discuss their applications to treatment of fungal and viral disease. We also discuss advantageous of CRISPR/Cas9 technology to drug design, creation of animal model, and to food, agricultural and energy sciences. Adoption of the CRISPR/Cas9 technology in biomedical and biotechnological researches would create innovative applications of it not only for breeding of strains exhibiting desired traits for specific industrial and medical applications, but also for investigation of genome function.

  13. Applications of Ecological Engineering Remedies for Uranium Processing Sites, USA

    Energy Technology Data Exchange (ETDEWEB)

    Waugh, William [Navarro Research and Engineering

    2016-05-23

    The U.S. Department of Energy (USDOE) is responsible for remediation of environmental contamination and long-term stewardship of sites associated with the legacy of nuclear weapons production during the Cold War in the United States. Protection of human health and the environment will be required for hundreds or even thousands of years at many legacy sites. USDOE continually evaluates and applies advances in science and technology to improve the effectiveness and sustainability of surface and groundwater remedies (USDOE 2011). This paper is a synopsis of ecological engineering applications that USDOE is evaluating to assess the effectiveness of remedies at former uranium processing sites in the southwestern United States. Ecological engineering remedies are predicated on the concept that natural ecological processes at legacy sites, once understood, can be beneficially enhanced or manipulated. Advances in tools for characterizing key processes and for monitoring remedy performance are demonstrating potential. We present test cases for four ecological engineering remedies that may be candidates for international applications.

  14. Customizing CAD system and its application for engineering design

    International Nuclear Information System (INIS)

    Shin, Jeong Ho; Kwak, Byung Man

    2003-01-01

    The computer is an important tool to design an engineering system and CAD systems are widely used for various design practice. To meet the market requirements, the old mass production system is being changed into the mass customization system. As for CAD systems, it is increasingly required to extend, automate, and customize a wide range of functionality. This article describes the state-of-the-art of the principal technologies for customizing CAD systems. And we have implemented an application that enables the parametric design by directly inputting numerical values of parameters for a CAD model. Based on this application, we have developed another system that makes it possible sharing of part family data between SolidEdge and Pro/Engineer. Through customization of CAD systems, it is possible to improve the product quality using external knowledge-based systems or to integrate with external system such as CAE tools. This paper can be a guide for engineering designers who want to customize CAD systems

  15. Grouting applications in civil engineering. Volume I and II

    International Nuclear Information System (INIS)

    Einstein, H.H.; Barvenik, M.J.

    1975-01-01

    A comprehensive description of grouting applications in civil engineering is presented that can serve as a basis for the selection of grouting methods in the borehole sealing problem. The breadth and depth of the study was assured by conducting the main part of the review, the collection and evaluation of information, without specifically considering the borehole sealing problem (but naturally incorporating any aspect of civil engineering applications that could be of potential use). Grouting is very much an art and not a science. In most cases, it is a trial and error procedure where an inexpensive method is initially tried and then a more expensive one is used until the desired results are obtained. Once a desired effect is obtained, it is difficult to credit any one procedure with the success because the results are due to the summation of all the methods used. In many cases, the method that proves successful reflects a small abnormality in the ground or structure rather than its overall characteristics. Hence, successful grouting relies heavily on good engineering judgement and experience, and not on a basic set of standard correlations or equations. 800 references

  16. Ion engine auxiliary propulsion applications and integration study

    Science.gov (United States)

    Zafran, S. (Editor)

    1977-01-01

    The benefits derived from application of the 8-cm mercury electron bombardment ion thruster were assessed. Two specific spacecraft missions were studied. A thruster was tested to provide additional needed information on its efflux characteristics and interactive effects. A Users Manual was then prepared describing how to integrate the thruster for auxiliary propulsion on geosynchronous satellites. By incorporating ion engines on an advanced communications mission, the weight available for added payload increases by about 82 kg (181 lb) for a 100 kg (2200 lb) satellite which otherwise uses electrothermal hydrazine. Ion engines can be integrated into a high performance propulsion module that is compatible with the multimission modular spacecraft and can be used for both geosynchronous and low earth orbit applications. The low disturbance torques introduced by the ion engines permit accurate spacecraft pointing with the payload in operation during thrusting periods. The feasibility of using the thruster's neutralizer assembly for neutralization of differentially charged spacecraft surfaces at geosynchronous altitude was demonstrated during the testing program.

  17. Detection Damage in Bearing System of Jet Engine Using the Vibroacoustic Method

    Directory of Open Access Journals (Sweden)

    Żokowski Mariusz

    2017-09-01

    Full Text Available The article discusses typical, operational systems for monitoring vibrations of jet engines, which constitute the propulsion of combat aircraft of the Armed Forces of the Republic of Poland. After that, the paper presents the stage of installing vibration measuring sensors in the direct area of one of the jet engine bearings, which is a support system for its rotor. The article discusses results of carried out analyses of data gathered during tests of the engine in the conditions a jet engine test bed. Results of detecting damages to the bear-ing, using sensors built in the direct area will be presented.

  18. Modeling and Detection of Ice Particle Accretion in Aircraft Engine Compression Systems

    Science.gov (United States)

    May, Ryan D.; Simon, Donald L.; Guo, Ten-Huei

    2012-01-01

    The accretion of ice particles in the core of commercial aircraft engines has been an ongoing aviation safety challenge. While no accidents have resulted from this phenomenon to date, numerous engine power loss events ranging from uneventful recoveries to forced landings have been recorded. As a first step to enabling mitigation strategies during ice accretion, a detection scheme must be developed that is capable of being implemented on board modern engines. In this paper, a simple detection scheme is developed and tested using a realistic engine simulation with approximate ice accretion models based on data from a compressor design tool. These accretion models are implemented as modified Low Pressure Compressor maps and have the capability to shift engine performance based on a specified level of ice blockage. Based on results from this model, it is possible to detect the accretion of ice in the engine core by observing shifts in the typical sensed engine outputs. Results are presented in which, for a 0.1 percent false positive rate, a true positive detection rate of 98 percent is achieved.

  19. Molecular and chemical engineering of bacteriophages for potential medical applications.

    Science.gov (United States)

    Hodyra, Katarzyna; Dąbrowska, Krystyna

    2015-04-01

    Recent progress in molecular engineering has contributed to the great progress of medicine. However, there are still difficult problems constituting a challenge for molecular biology and biotechnology, e.g. new generation of anticancer agents, alternative biosensors or vaccines. As a biotechnological tool, bacteriophages (phages) offer a promising alternative to traditional approaches. They can be applied as anticancer agents, novel platforms in vaccine design, or as target carriers in drug discovery. Phages also offer solutions for modern cell imaging, biosensor construction or food pathogen detection. Here we present a review of bacteriophage research as a dynamically developing field with promising prospects for further development of medicine and biotechnology.

  20. A special issue on reviews in biomedical applications of nanomaterials, tissue engineering, stem cells, bioimaging, and toxicity.

    Science.gov (United States)

    Nalwa, Hari Singh

    2014-10-01

    This second special issue of the Journal of Biomedical Nanotechnology in a series contains another 30 state-of-the-art reviews focused on the biomedical applications of nanomaterials, biosensors, bone tissue engineering, MRI and bioimaging, single-cell detection, stem cells, endothelial progenitor cells, toxicity and biosafety of nanodrugs, nanoparticle-based new therapeutic approaches for cancer, hepatic and cardiovascular disease.

  1. Computer- Aided Design in Power Engineering Application of Software Tools

    CERN Document Server

    Stojkovic, Zlatan

    2012-01-01

    This textbooks demonstrates the application of software tools in solving a series of problems from the field of designing power system structures and systems. It contains four chapters: The first chapter leads the reader through all the phases necessary in the procedures of computer aided modeling and simulation. It guides through the complex problems presenting on the basis of eleven original examples. The second chapter presents  application of software tools in power system calculations of power systems equipment design. Several design example calculations are carried out using engineering standards like MATLAB, EMTP/ATP, Excel & Access, AutoCAD and Simulink. The third chapters focuses on the graphical documentation using a collection of software tools (AutoCAD, EPLAN, SIMARIS SIVACON, SIMARIS DESIGN) which enable the complete automation of the development of graphical documentation of a power systems. In the fourth chapter, the application of software tools in the project management in power systems ...

  2. Photoreconfigurable polymers for biomedical applications: chemistry and macromolecular engineering.

    Science.gov (United States)

    Zhu, Congcong; Ninh, Chi; Bettinger, Christopher J

    2014-10-13

    Stimuli-responsive polymers play an important role in many biomedical technologies. Light responsive polymers are particularly desirable because the parameters of irradiated light and diverse photoactive chemistries produce a large number of combinations between functional materials and associated stimuli. This Review summarizes recent advances in utilizing photoactive chemistries in macromolecules for prospective use in biomedical applications. Special focus is granted to selection criterion when choosing photofunctional groups. Synthetic strategies to incorporate these functionalities into polymers and networks with different topologies are also highlighted herein. Prospective applications of these materials are discussed including programmable matrices for controlled release, dynamic scaffolds for tissue engineering, and functional coatings for medical devices. The article concludes by summarizing the state of the art in photoresponsive polymers for biomedical applications including current challenges and future opportunities.

  3. Laser ignition - Spark plug development and application in reciprocating engines

    Science.gov (United States)

    Pavel, Nicolaie; Bärwinkel, Mark; Heinz, Peter; Brüggemann, Dieter; Dearden, Geoff; Croitoru, Gabriela; Grigore, Oana Valeria

    2018-03-01

    Combustion is one of the most dominant energy conversion processes used in all areas of human life, but global concerns over exhaust gas pollution and greenhouse gas emission have stimulated further development of the process. Lean combustion and exhaust gas recirculation are approaches to improve the efficiency and to reduce pollutant emissions; however, such measures impede reliable ignition when applied to conventional ignition systems. Therefore, alternative ignition systems are a focus of scientific research. Amongst others, laser induced ignition seems an attractive method to improve the combustion process. In comparison with conventional ignition by electric spark plugs, laser ignition offers a number of potential benefits. Those most often discussed are: no quenching of the combustion flame kernel; the ability to deliver (laser) energy to any location of interest in the combustion chamber; the possibility of delivering the beam simultaneously to different positions, and the temporal control of ignition. If these advantages can be exploited in practice, the engine efficiency may be improved and reliable operation at lean air-fuel mixtures can be achieved, making feasible savings in fuel consumption and reduction in emission of exhaust gasses. Therefore, laser ignition can enable important new approaches to address global concerns about the environmental impact of continued use of reciprocating engines in vehicles and power plants, with the aim of diminishing pollutant levels in the atmosphere. The technology can also support increased use of electrification in powered transport, through its application to ignition of hybrid (electric-gas) engines, and the efficient combustion of advanced fuels. In this work, we review the progress made over the last years in laser ignition research, in particular that aimed towards realizing laser sources (or laser spark plugs) with dimensions and properties suitable for operating directly on an engine. The main envisaged

  4. Application of software engineering to development of reactor safety codes

    International Nuclear Information System (INIS)

    Wilburn, N.P.; Niccoli, L.G.

    1981-01-01

    Software Engineering, which is a systematic methodology by which a large scale software development project is partitioned into manageable pieces, has been applied to the development of LMFBR safety codes. The techniques have been applied extensively in the business and aerospace communities and have provided an answer to the drastically increasing cost of developing and maintaining software. The five phases of software engineering (Survey, Analysis, Design, Implementation, and Testing) were applied in turn to development of these codes, along with Walkthroughs (peer review) at each stage. The application of these techniques has resulted in SUPERIOR SOFTWARE which is well documented, thoroughly tested, easy to modify, easier to use and maintain. The development projects have resulted in lower overall cost. (orig.) [de

  5. Magnetic Resonance Imaging and Velocity Mapping in Chemical Engineering Applications.

    Science.gov (United States)

    Gladden, Lynn F; Sederman, Andrew J

    2017-06-07

    This review aims to illustrate the diversity of measurements that can be made using magnetic resonance techniques, which have the potential to provide insights into chemical engineering systems that cannot readily be achieved using any other method. Perhaps the most notable advantage in using magnetic resonance methods is that both chemistry and transport can be followed in three dimensions, in optically opaque systems, and without the need for tracers to be introduced into the system. Here we focus on hydrodynamics and, in particular, applications to rheology, pipe flow, and fixed-bed and gas-solid fluidized bed reactors. With increasing development of industrially relevant sample environments and undersampling data acquisition strategies that can reduce acquisition times to chemical engineering research.

  6. Lead-free bearing alloys for engine applications

    Science.gov (United States)

    Ratke, Lorenz; Ågren, John; Ludwig, Andreas; Tonn, Babette; Gránásy, László; Mathiesen, Ragnvald; Arnberg, Lars; Anger, Gerd; Reifenhäuser, Bernd; Lauer, Michael; Garen, Rune; Gust, Edgar

    2005-10-01

    Recent developments to reduce the fuel consumption, emission and air pollution, size and weight of engines for automotive, truck, ship propulsion and electrical power generation lead to temperature and load conditions within the engines that cannot be borne by conventional bearings. Presently, only costly multilayer bearings with electroplated or sputtered surface coatings can cope with the load/speed combinations required. Ecological considerations in recent years led to a ban by the European Commission on the use of lead in cars a problem for the standard bronze-lead bearing material. This MAP project is therefore developing an aluminium-based lead-free bearing material with sufficient hardness, wear and friction properties and good corrosion resistance. Only alloys made of components immiscible in the molten state can meet the demanding requirements. Space experimentation plays a crucial role in optimising the cast microstructure for such applications.

  7. Knowledge Engineering Aspects of Affective Bi-Modal Educational Applications

    Science.gov (United States)

    Alepis, Efthymios; Virvou, Maria; Kabassi, Katerina

    This paper analyses the knowledge and software engineering aspects of educational applications that provide affective bi-modal human-computer interaction. For this purpose, a system that provides affective interaction based on evidence from two different modes has been developed. More specifically, the system's inferences about students' emotions are based on user input evidence from the keyboard and the microphone. Evidence from these two modes is combined by a user modelling component that incorporates user stereotypes as well as a multi criteria decision making theory. The mechanism that integrates the inferences from the two modes has been based on the results of two empirical studies that were conducted in the context of knowledge engineering of the system. The evaluation of the developed system showed significant improvements in the recognition of the emotional states of users.

  8. Intelligent computer systems in engineering design principles and applications

    CERN Document Server

    Sunnersjo, Staffan

    2016-01-01

    This introductory book discusses how to plan and build useful, reliable, maintainable and cost efficient computer systems for automated engineering design. The book takes a user perspective and seeks to bridge the gap between texts on principles of computer science and the user manuals for commercial design automation software. The approach taken is top-down, following the path from definition of the design task and clarification of the relevant design knowledge to the development of an operational system well adapted for its purpose. This introductory text for the practicing engineer working in industry covers most vital aspects of planning such a system. Experiences from applications of automated design systems in practice are reviewed based on a large number of real, industrial cases. The principles behind the most popular methods in design automation are presented with sufficient rigour to give the user confidence in applying them on real industrial problems. This book is also suited for a half semester c...

  9. Decomposition techniques in mathematical programming engineering and science applications

    CERN Document Server

    Conejo, Antonio J; Minguez, Roberto; Garcia-Bertrand, Raquel

    2006-01-01

    Optimization plainly dominates the design, planning, operation, and c- trol of engineering systems. This is a book on optimization that considers particular cases of optimization problems, those with a decomposable str- ture that can be advantageously exploited. Those decomposable optimization problems are ubiquitous in engineering and science applications. The book considers problems with both complicating constraints and complicating va- ables, and analyzes linear and nonlinear problems, with and without in- ger variables. The decomposition techniques analyzed include Dantzig-Wolfe, Benders, Lagrangian relaxation, Augmented Lagrangian decomposition, and others. Heuristic techniques are also considered. Additionally, a comprehensive sensitivity analysis for characterizing the solution of optimization problems is carried out. This material is particularly novel and of high practical interest. This book is built based on many clarifying, illustrative, and compu- tional examples, which facilitate the learning p...

  10. Mobile Timekeeping Application Built on Reverse-Engineered JPL Infrastructure

    Science.gov (United States)

    Witoff, Robert J.

    2013-01-01

    Every year, non-exempt employees cumulatively waste over one man-year tracking their time and using the timekeeping Web page to save those times. This app eliminates this waste. The innovation is a native iPhone app. Libraries were built around a reverse- engineered JPL API. It represents a punch-in/punch-out paradigm for timekeeping. It is accessible natively via iPhones, and features ease of access. Any non-exempt employee can natively punch in and out, as well as save and view their JPL timecard. This app is built on custom libraries created by reverse-engineering the standard timekeeping application. Communication is through custom libraries that re-route traffic through BrowserRAS (remote access service). This has value at any center where employees track their time.

  11. Elements of quantum computing history, theories and engineering applications

    CERN Document Server

    Akama, Seiki

    2015-01-01

    A quantum computer is a computer based on a computational model which uses quantum mechanics, which is a subfield of physics to study phenomena at the micro level. There has been a growing interest on quantum computing in the 1990's, and some quantum computers at the experimental level were recently implemented. Quantum computers enable super-speed computation, and can solve some important problems whose solutions were regarded impossible or intractable with traditional computers. This book provides a quick introduction to quantum computing for readers who have no backgrounds of both theory of computation and quantum mechanics. “Elements of Quantum Computing” presents the history, theories, and engineering applications of quantum computing. The book is suitable to computer scientists, physicist, and software engineers.

  12. Nonparametric statistics with applications to science and engineering

    CERN Document Server

    Kvam, Paul H

    2007-01-01

    A thorough and definitive book that fully addresses traditional and modern-day topics of nonparametric statistics This book presents a practical approach to nonparametric statistical analysis and provides comprehensive coverage of both established and newly developed methods. With the use of MATLAB, the authors present information on theorems and rank tests in an applied fashion, with an emphasis on modern methods in regression and curve fitting, bootstrap confidence intervals, splines, wavelets, empirical likelihood, and goodness-of-fit testing. Nonparametric Statistics with Applications to Science and Engineering begins with succinct coverage of basic results for order statistics, methods of categorical data analysis, nonparametric regression, and curve fitting methods. The authors then focus on nonparametric procedures that are becoming more relevant to engineering researchers and practitioners. The important fundamental materials needed to effectively learn and apply the discussed methods are also provide...

  13. Computational intelligence in time series forecasting theory and engineering applications

    CERN Document Server

    Palit, Ajoy K

    2005-01-01

    Foresight in an engineering enterprise can make the difference between success and failure, and can be vital to the effective control of industrial systems. Applying time series analysis in the on-line milieu of most industrial plants has been problematic owing to the time and computational effort required. The advent of soft computing tools offers a solution. The authors harness the power of intelligent technologies individually and in combination. Examples of the particular systems and processes susceptible to each technique are investigated, cultivating a comprehensive exposition of the improvements on offer in quality, model building and predictive control and the selection of appropriate tools from the plethora available. Application-oriented engineers in process control, manufacturing, production industry and research centres will find much to interest them in this book. It is suitable for industrial training purposes, as well as serving as valuable reference material for experimental researchers.

  14. A comparison of damage detection methods applied to civil engineering structures

    DEFF Research Database (Denmark)

    Gres, Szymon; Andersen, Palle; Johansen, Rasmus Johan

    2018-01-01

    Facilitating detection of early-stage damage is crucial for in-time repairs and cost-optimized maintenance plans of civil engineering structures. Preferably, the damage detection is performed by use of output vibration data, hereby avoiding modal identification of the structure. Most of the work...

  15. A comparison of damage detection methods applied to civil engineering structures

    DEFF Research Database (Denmark)

    Gres, Szymon; Andersen, Palle; Johansen, Rasmus Johan

    2017-01-01

    Facilitating detection of early-stage damage is crucial for in-time repairs and cost-optimized maintenance plans of civil engineering structures. Preferably, the damage detection is performed by use of output vibration data, hereby avoiding modal identification of the structure. Most of the work...

  16. Engineering Support for Handling Controller Conflicts in Energy Storage Systems Applications

    Directory of Open Access Journals (Sweden)

    Claudia Zanabria

    2017-10-01

    Full Text Available Energy storage systems will play a major role in the decarbonization of future sustainable electric power systems, allowing a high penetration of distributed renewable energy sources and contributing to the distribution network stability and reliability. To accomplish this, a storage system is required to provide multiple services such as self-consumption, grid support, peak-shaving, etc. The simultaneous activation of controllers operation may lead to conflicts, as a consequence the execution of committed services is not guaranteed. This paper presents and discusses a solution to the exposed issue by developing an engineering support approach to semi-automatically detect and handle conflicts for multi-usage storage systems applications. To accomplish that an ontology is developed and exploited by model-driven engineering mechanisms. The proposed approach is evaluated by implementing a use case example, where detection of conflicts is automatically done at an early design stage. Besides this, exploitable source code for conflicts resolution is generated and used during the design and prototype stages of controllers development. Thus, the proposed engineering support enhances the design and development of storage system controllers, especially for multi-usage applications.

  17. 2D modelling and its applications in engineering

    International Nuclear Information System (INIS)

    Altinbalik, M. Tahir; İRSEL, Gürkan

    2013-01-01

    A model, in computer aided engineering applications, may be created by either using a two- dimensional or a three-dimensional design depending on the purpose of design. What matters most in this regard is the selection of a right method to meet system solution requirements in the most economical way. Manufacturability of a design that is developed by utilising computer aided engineering is important, but usability of the data obtained in the course of design works in the production is also equally important. In the applications consisting of such production operations as CNC or plasma cutting, two-dimensional designs can be directly used in production. These machines are equipped with interfaces which converts two-dimensional drawings into codes. In this way, a design can be directly transferred to production, and any arrangements during production process can be synchronously evaluated. As a result of this, investment expenses will be lowered, and thus the costs can be reduced to some extent. In the presented study, we have studied two-dimensional design applications and requirements. We created a two-dimensional design for a part for which a three-dimensional model have previously been generated, and then, we transferred this design to plasma cutting machine, and thus, the operation has been realized experimentally. Key words: Plasma Cutting, 2D modelling, flexibility

  18. 2D modelling and its applications in engineering

    Energy Technology Data Exchange (ETDEWEB)

    Altinbalik, M. Tahir; İRSEL, Gürkan [Trakya University, Faculty of Engineering and Architecture Mechanical Engineering Department, Edİrne (Turkey)

    2013-07-01

    A model, in computer aided engineering applications, may be created by either using a two- dimensional or a three-dimensional design depending on the purpose of design. What matters most in this regard is the selection of a right method to meet system solution requirements in the most economical way. Manufacturability of a design that is developed by utilising computer aided engineering is important, but usability of the data obtained in the course of design works in the production is also equally important. In the applications consisting of such production operations as CNC or plasma cutting, two-dimensional designs can be directly used in production. These machines are equipped with interfaces which converts two-dimensional drawings into codes. In this way, a design can be directly transferred to production, and any arrangements during production process can be synchronously evaluated. As a result of this, investment expenses will be lowered, and thus the costs can be reduced to some extent. In the presented study, we have studied two-dimensional design applications and requirements. We created a two-dimensional design for a part for which a three-dimensional model have previously been generated, and then, we transferred this design to plasma cutting machine, and thus, the operation has been realized experimentally. Key words: Plasma Cutting, 2D modelling, flexibility.

  19. Radar application in void and bar detection

    International Nuclear Information System (INIS)

    Amry Amin Abas; Mohamad Pauzi Ismail; Suhairy Sani

    2003-01-01

    Radar is one of the new non-destructive testing techniques for concrete and structures inspection. Radar is a non-ionizing electromagnetic wave that can penetrate deep into concrete or soil in about several tenths of meters. Method of inspection using radar enables us to perform high resolution detection, imaging and mapping of subsurface concrete and soil condition. This paper will discuss the use of radar for void and bar detection and sizing. The samples used in this paper are custom made samples and comparison will be made to validate the use of radar in detecting, locating and also size determination of voids and bars. (Author)

  20. Enhanced Airport Surface Detection Equipment Applications,

    Science.gov (United States)

    1985-04-17

    of runway capacity for the single mixed runway case . The ASDE display, however, provides independent position and timing information on runway...restored to within approximately 5 percent of the good visibility capacity for the single mixed runway case . The lack of identity informa- tion on the ASDE...D.C. 20591 ENGINEERING AND ECONOMICS RESEARCH, INC. Technical Support Staff Henry R. Schramm Mignonette E. Stephen A-2 I m i . . . -i , ’ ,.i

  1. Chitosan for gene delivery and orthopedic tissue engineering applications.

    Science.gov (United States)

    Raftery, Rosanne; O'Brien, Fergal J; Cryan, Sally-Ann

    2013-05-15

    Gene therapy involves the introduction of foreign genetic material into cells in order exert a therapeutic effect. The application of gene therapy to the field of orthopaedic tissue engineering is extremely promising as the controlled release of therapeutic proteins such as bone morphogenetic proteins have been shown to stimulate bone repair. However, there are a number of drawbacks associated with viral and synthetic non-viral gene delivery approaches. One natural polymer which has generated interest as a gene delivery vector is chitosan. Chitosan is biodegradable, biocompatible and non-toxic. Much of the appeal of chitosan is due to the presence of primary amine groups in its repeating units which become protonated in acidic conditions. This property makes it a promising candidate for non-viral gene delivery. Chitosan-based vectors have been shown to transfect a number of cell types including human embryonic kidney cells (HEK293) and human cervical cancer cells (HeLa). Aside from its use in gene delivery, chitosan possesses a range of properties that show promise in tissue engineering applications; it is biodegradable, biocompatible, has anti-bacterial activity, and, its cationic nature allows for electrostatic interaction with glycosaminoglycans and other proteoglycans. It can be used to make nano- and microparticles, sponges, gels, membranes and porous scaffolds. Chitosan has also been shown to enhance mineral deposition during osteogenic differentiation of MSCs in vitro. The purpose of this review is to critically discuss the use of chitosan as a gene delivery vector with emphasis on its application in orthopedic tissue engineering.

  2. Hydraulic modeling development and application in water resources engineering

    Science.gov (United States)

    Simoes, Francisco J.; Yang, Chih Ted; Wang, Lawrence K.

    2015-01-01

    The use of modeling has become widespread in water resources engineering and science to study rivers, lakes, estuaries, and coastal regions. For example, computer models are commonly used to forecast anthropogenic effects on the environment, and to help provide advanced mitigation measures against catastrophic events such as natural and dam-break floods. Linking hydraulic models to vegetation and habitat models has expanded their use in multidisciplinary applications to the riparian corridor. Implementation of these models in software packages on personal desktop computers has made them accessible to the general engineering community, and their use has been popularized by the need of minimal training due to intuitive graphical user interface front ends. Models are, however, complex and nontrivial, to the extent that even common terminology is sometimes ambiguous and often applied incorrectly. In fact, many efforts are currently under way in order to standardize terminology and offer guidelines for good practice, but none has yet reached unanimous acceptance. This chapter provides a view of the elements involved in modeling surface flows for the application in environmental water resources engineering. It presents the concepts and steps necessary for rational model development and use by starting with the exploration of the ideas involved in defining a model. Tangible form of those ideas is provided by the development of a mathematical and corresponding numerical hydraulic model, which is given with a substantial amount of detail. The issues of model deployment in a practical and productive work environment are also addressed. The chapter ends by presenting a few model applications highlighting the need for good quality control in model validation.

  3. Application of ionizing radiation processing in biomedical engineering and microelectronics

    International Nuclear Information System (INIS)

    Hongfej, H.; Jilan, W.

    1988-01-01

    The applied radiation chemistry has made great contributions to the development of polymeric industrial materials by the characteristics reaction means such as crosslinking, graft copolymerization and low-temperature or solid-phase polymerization, and become a important field on peaceful use of atomic energy. A brief review on the applications of ionizing radiation processing in biomedical engineering and microelectronics is presented. The examples of this technique were the studies on biocompatible and biofunctional polymers for medical use and on resists of lithography in microelectronics

  4. Performance assessment of advanced engineering workstations for fuel management applications

    International Nuclear Information System (INIS)

    Turinsky, P.J.

    1989-07-01

    The purpose of this project was to assess the performance of an advanced engineering workstation [AEW] with regard to applications to incore fuel management for LWRs. The attributes of most interest to us that define an AEW are parallel computational hardware and graphics capabilities. The AEWs employed were super microcomputers manufactured by MASSCOMP, Inc. These computers utilize a 32-bit architecture, graphics co-processor, multi-CPUs [up to six] attached to common memory and multi-vector accelerators. 7 refs., 33 figs., 4 tabs

  5. Robotic applications at the Idaho National Engineering Laboratory

    International Nuclear Information System (INIS)

    Griebenow, B.E.; Marts, D.J.

    1990-01-01

    The Idaho National Engineering Laboratory (INEL) has several programs and projected programs that involve work in hazardous environments. Robotics/remote handling technology is being considered for an active role in these programs. The most appealing aspect of using robotics is in the area of personnel safety. Any task requiring an individual to enter a hazardous or potentially hazardous environment can benefit substantially from robotics by removing the operator from the environment and having him conduct the work remotely. Several INEL programs were evaluated based on their applications for robotics and the results and some conclusions are discussed in this paper. 1 fig

  6. Applications of ionizing radiation processing in biomedical engineering and microelectronics

    International Nuclear Information System (INIS)

    Ha Hongfei; Wu Jilan

    1987-01-01

    The applied radiation chemistry has made great contributions to the development of polymeric industrial materials by the characteristic reaction means such as corsslinking, graft copolymerization and low-temperature or solid-phase polymerization, and become an important field on peaceful use of atomic energy. A brief review on the applications of ionizing radiation processing in biomedical engineering and microelectronics is presented. The examples of this techique were the studies on biocompatible and biofunctional polymers for medical use and on resists of lithography in microelectronics. (author)

  7. Development of biosensors and their application in metabolic engineering

    DEFF Research Database (Denmark)

    Zhang, Jie; Jensen, Michael Krogh; Keasling, Jay

    2015-01-01

    and ease of implementation with high-throughput analysis. Here we describe recent progress in biosensor development and their applications in a metabolic engineering context. We also highlight examples of how biosensors can be integrated with synthetic circuits to exert feedback regulation...... for the desired phenotypes. However, methods available for microbial genome diversification far exceed our ability to screen and select for those variants with optimal performance. Genetically encoded biosensors have shown the potential to address this gap, given their ability to respond to small molecule binding...

  8. Nanoscale biomaterial interface modification for advanced tissue engineering applications

    International Nuclear Information System (INIS)

    Safonov, V; Zykova, A; Smolik, J; Rogovska, R; Donkov, N; Goltsev, A; Dubrava, T; Rassokha, I; Georgieva, V

    2012-01-01

    Recently, various stem cells, including mesenchymal stem cells (MSCs), have been found to have considerable potential for application in tissue engineering and future advanced therapies due to their biological capability to differentiate into specific lineages. Modified surface properties, such as composition, nano-roughness and wettability, affect the most important processes at the biomaterial interface. The aim of the present is work is to study the stem cells' (MSCs) adhesive potential, morphology, phenotypical characteristics in in vitro tests, and to distinguish betwen the different factors influencing the cell/biomaterial interaction, such as nano-topography, surface chemistry and surface free energy.

  9. Automatic invariant detection in dynamic web applications

    NARCIS (Netherlands)

    Groeneveld, F.; Mesbah, A.; Van Deursen, A.

    2010-01-01

    The complexity of modern web applications increases as client-side JavaScript and dynamic DOM programming are used to offer a more interactive web experience. In this paper, we focus on improving the dependability of such applications by automatically inferring invariants from the client-side and

  10. Plagiarism detection and prevention techniques in engineering education

    OpenAIRE

    Halak, Basel; El-Hajjar, Mohammed

    2016-01-01

    Plagiarism seriously damages the education process in a number of ways; it prevents students from developing the skills of creative thinking and critical analysis; it undermines the trust between lectures and students, and if goes undetected, it can impact the reputation of the academic institution and devalue its degrees. In this paper, we present two techniques for plagiarism detection and prevention. The first method is based on the allocation of a unique assignment for each student, and t...

  11. Osteochondral tissue engineering: scaffolds, stem cells and applications

    Science.gov (United States)

    Nooeaid, Patcharakamon; Salih, Vehid; Beier, Justus P; Boccaccini, Aldo R

    2012-01-01

    Osteochondral tissue engineering has shown an increasing development to provide suitable strategies for the regeneration of damaged cartilage and underlying subchondral bone tissue. For reasons of the limitation in the capacity of articular cartilage to self-repair, it is essential to develop approaches based on suitable scaffolds made of appropriate engineered biomaterials. The combination of biodegradable polymers and bioactive ceramics in a variety of composite structures is promising in this area, whereby the fabrication methods, associated cells and signalling factors determine the success of the strategies. The objective of this review is to present and discuss approaches being proposed in osteochondral tissue engineering, which are focused on the application of various materials forming bilayered composite scaffolds, including polymers and ceramics, discussing the variety of scaffold designs and fabrication methods being developed. Additionally, cell sources and biological protein incorporation methods are discussed, addressing their interaction with scaffolds and highlighting the potential for creating a new generation of bilayered composite scaffolds that can mimic the native interfacial tissue properties, and are able to adapt to the biological environment. PMID:22452848

  12. 48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation.

    Science.gov (United States)

    2010-10-01

    ... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

  13. Molecular engineering and fluorescence for the detection of toxic cations

    International Nuclear Information System (INIS)

    Souchon, V.

    2007-11-01

    This work is a part of the 'Toxicologie Nucleaire Environnementale' program which aims at studying the effects on the living of heavy metals or radionuclides involved in nuclear industry. Most particularly, it deals with the design of new fluorescent sensors for the selective detection of Pb 2+ , Cd 2+ and Cs + in biological media. Several fluorescent calixarenes possessing nitrogen atoms were synthesized and their properties as potential lead sensors were investigated. One of them could be used in experimental conditions close to biological media and new target compounds with amide functional groups were proposed. Many approaches were considered for the design of selective fluorescent sensors for cadmium. On the basis of literature results, many chelating compounds incorporating sulfur atoms were synthesized but showed no significant affinity towards cadmium. On the opposite, compounds functionalized with several pyridine-2'-yl-1,2,3-triazol fluorescent moieties linked to a β-cyclodextrin or a calix[4]arene showed good affinity for cadmium in methanol, but the selectivity was found to be insufficient. In contrast, very satisfying results in terms of both selectivity and sensitivity could be obtained with the commercial calcium sensor Rhod-5N in an aqueous medium at neutral pH. Lastly, micromolar detection limits for the selective detection of caesium were reached in an aqueous medium at neutral pH thanks to a new sulfonated fluorescent calixarene with two appended crown-ethers. An original complexation mechanism was proposed and validated by molecular modelling (DFT). (author)

  14. APPLICATION FRAMEWORK IN ENGINEERING SERVICE ORIENTED ARCHITECTURE SYSTEM SERVICE

    Directory of Open Access Journals (Sweden)

    Ade Hodijah

    2017-03-01

    Full Text Available The Service Engineering (SE is understood as a framework to create innovative services in application development of information technology approach to Service Oriented Architecture (SOA. Implementing SOA is required methodology to identify services that can be used again in the application and organization of a company. in this research, software development model used is object-oriented methodologies, SOA itself is a collection consisting of tools, technologies, frameworks, and best practices that facilitate the implementation of a service quickly. in a study this uses the tools of Business Process Management System (BPMS to support the implementation of service-oriented software. the purpose of this study is to produce a model of activities and artifacts of the application software development models of the SE with a case study Rate Loans. Validation to the design of the model is done through testing of the software produced. The results showed that the application of the SE in the development of service-oriented software can use the object-oriented methodology by providing additional value-added analysis and redesign of business processes to be implemented on a BPMS. BPMS usage of the application of the SE on the SOA has the advantage of visualization in the management of business processes.

  15. Explosives detection with applications to landmines

    International Nuclear Information System (INIS)

    Lanza, R.C.

    1998-01-01

    Modern mines have been made difficult to detect by conventional means such as magnetic detection. The problem is not only that there is often only a small amount of metal in the mine but that the war zone may contain an enormous amount of metal pieces from other weapons. Thus the problem is not just one of detection, but of developing methods to discriminate between many kinds of background and clutter that are present. One of techniques is the use of fast neutrons to probe material with subsequent spectrometry of gamma rays produced by inelastic neutron interactions. Another approach is the use of an infrared camera to detect mines after heating soil with a large heater. Certain advantages has Nuclear Quadrupole Resonance to detect nitrogen in compounds such as TNT. Use of remote controlled mechanical devices to detonate mines can also be considered. It is important to note that no single device will solve the problem and therefore it will be more effective to build devices specific to problem

  16. Transglutaminase reactivity with gelatine: perspective applications in tissue engineering.

    Science.gov (United States)

    Bertoni, F; Barbani, N; Giusti, P; Ciardelli, G

    2006-05-01

    Gelatine was crosslinked by means of an enzymatic treatment using tissue transglutaminase (tTGase) (Sigma) and microbial transglutaminase (mTGase) (Ajinomoto) which catalyses the formation of isopeptide bonds between the gamma-carbonyl group of a glutamine residue and the epsilon-amino group of a lysine residue. The reaction is an interesting alternative to the traditional glutaraldehyde crosslinking, which has several drawbacks (e.g., in medical application) due to the toxicity of the chemical reagent. To further investigate the possibility to utilize the modified protein for tissue engineering application, TGase crosslinked gelatine was incorporated in a gellan matrix, a polysaccharide, to enhance the stability in aqueous media. Films obtained by casting were characterized by thermal analysis, chemical imaging, swelling behaviour and cell adhesion.

  17. Modelling of Electrokinetic Processes in Civil and Environmental Engineering Applications

    DEFF Research Database (Denmark)

    Paz-Garcia, Juan Manuel; Johannesson, Björn; Ottosen, Lisbeth M.

    2011-01-01

    conditions are assumed between the aqueous species and the solid matrix for a set of feasible chemical equilibrium reactions defined for each specific application. A module for re-establishing the chemical equilibrium has been developed and included in the system for this purpose. Changes in the porosity......A mathematical model for the electrokinetic phenomena is described. Numerical simulations of different applications of electrokinetic techniques to the fields of civil and environmental engineering are included, showing the versatility and consistency of the model. The electrokinetics phenomena......-Nernst-Planck system of equations, accounting for ionic migration, chemical diffusion and advection is used for modeling the transport process. The advection term contributor is studied by including in the system the water transport through the porous media, mainly due to electroosmosis. The pore solution filling...

  18. Surface engineering of graphene-based nanomaterials for biomedical applications.

    Science.gov (United States)

    Shi, Sixiang; Chen, Feng; Ehlerding, Emily B; Cai, Weibo

    2014-09-17

    Graphene-based nanomaterials have attracted tremendous interest over the past decade due to their unique electronic, optical, mechanical, and chemical properties. However, the biomedical applications of these intriguing nanomaterials are still limited due to their suboptimal solubility/biocompatibility, potential toxicity, and difficulties in achieving active tumor targeting, just to name a few. In this Topical Review, we will discuss in detail the important role of surface engineering (i.e., bioconjugation) in improving the in vitro/in vivo stability and enriching the functionality of graphene-based nanomaterials, which can enable single/multimodality imaging (e.g., optical imaging, positron emission tomography, magnetic resonance imaging) and therapy (e.g., photothermal therapy, photodynamic therapy, and drug/gene delivery) of cancer. Current challenges and future research directions are also discussed and we believe that graphene-based nanomaterials are attractive nanoplatforms for a broad array of future biomedical applications.

  19. Applications of chaos and nonlinear dynamics in science and engineering

    CERN Document Server

    Rondoni, Lamberto; Mitra, Mala

    Chaos and nonlinear dynamics initially developed as a new emergent field with its foundation in physics and applied mathematics. The highly generic, interdisciplinary quality of the insights gained in the last few decades has spawned myriad applications in almost all branches of science and technology—and even well beyond. Wherever the quantitative modeling and analysis of complex, nonlinear phenomena are required, chaos theory and its methods can play a key role.    This second volume concentrates on reviewing further relevant, contemporary applications of chaotic nonlinear systems as they apply to the various cutting-edge branches of engineering. This encompasses, but is not limited to, topics such as the spread of epidemics; electronic circuits; chaos control in mechanical devices; secure communication; and digital watermarking. Featuring contributions from active and leading research groups, this collection is ideal both as a reference work and as a ‘recipe book’ full of tried and tested, successf...

  20. Basic Potential of Carbon Nanotubes in Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Hisao Haniu

    2012-01-01

    Full Text Available Carbon nanotubes (CNTs are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.

  1. Continuous nonlinear optimization for engineering applications in GAMS technology

    CERN Document Server

    Andrei, Neculai

    2017-01-01

    This book presents the theoretical details and computational performances of algorithms used for solving continuous nonlinear optimization applications imbedded in GAMS. Aimed toward scientists and graduate students who utilize optimization methods to model and solve problems in mathematical programming, operations research, business, engineering, and industry, this book enables readers with a background in nonlinear optimization and linear algebra to use GAMS technology to understand and utilize its important capabilities to optimize algorithms for modeling and solving complex, large-scale, continuous nonlinear optimization problems or applications. Beginning with an overview of constrained nonlinear optimization methods, this book moves on to illustrate key aspects of mathematical modeling through modeling technologies based on algebraically oriented modeling languages. Next, the main feature of GAMS, an algebraically oriented language that allows for high-level algebraic representation of mathematical opti...

  2. Synthesis of Graphene-Based Sensors and Application on Detecting SF6 Decomposing Products: A Review

    Directory of Open Access Journals (Sweden)

    Xiaoxing Zhang

    2017-02-01

    Full Text Available Graphene-based materials have aroused enormous focus on a wide range of engineering fields because of their unique structure. One of the most promising applications is gas adsorption and sensing. In electrical engineering, graphene-based sensors are also employed as detecting devices to estimate the operation status of gas insulated switchgear (GIS. This paper reviews the main synthesis methods of graphene, gas adsorption, and sensing mechanism of its based sensors, as well as their applications in detecting SF6 decomposing products, such as SO2, H2S, SO2F2, and SOF2, in GIS. Both theoretical and experimental researches on gas response of graphene-based sensors to these typical gases are summarized. Finally, the future research trend about graphene synthesis technique and relevant perspective are also given.

  3. Surface plasmon resonance application for herbicide detection

    Science.gov (United States)

    Chegel, Vladimir I.; Shirshov, Yuri M.; Piletskaya, Elena V.; Piletsky, Sergey A.

    1998-01-01

    The optoelectronic biosensor, based on Surface Plasmon Resonance (SPR) for detection of photosynthesis-inhibiting herbicides in aqueous solutions is presented. The pesticide capability to replace plastoquinone from its complex with D1 protein is used for the detection. This replacement reaction results in the changes of the optical characteristics of protein layer, immobilized on the gold surface. Monitoring of these changes with SPR-technique permit to determine 0.1 - 5.0 mkg/ml herbicide in solution within one hour.

  4. 3D bioprinting and the current applications in tissue engineering.

    Science.gov (United States)

    Huang, Ying; Zhang, Xiao-Fei; Gao, Guifang; Yonezawa, Tomo; Cui, Xiaofeng

    2017-08-01

    Bioprinting as an enabling technology for tissue engineering possesses the promises to fabricate highly mimicked tissue or organs with digital control. As one of the biofabrication approaches, bioprinting has the advantages of high throughput and precise control of both scaffold and cells. Therefore, this technology is not only ideal for translational medicine but also for basic research applications. Bioprinting has already been widely applied to construct functional tissues such as vasculature, muscle, cartilage, and bone. In this review, the authors introduce the most popular techniques currently applied in bioprinting, as well as the various bioprinting processes. In addition, the composition of bioink including scaffolds and cells are described. Furthermore, the most current applications in organ and tissue bioprinting are introduced. The authors also discuss the challenges we are currently facing and the great potential of bioprinting. This technology has the capacity not only in complex tissue structure fabrication based on the converted medical images, but also as an efficient tool for drug discovery and preclinical testing. One of the most promising future advances of bioprinting is to develop a standard medical device with the capacity of treating patients directly on the repairing site, which requires the development of automation and robotic technology, as well as our further understanding of biomaterials and stem cell biology to integrate various printing mechanisms for multi-phasic tissue engineering. Copyright © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Engineering Thermostable Microbial Xylanases Toward its Industrial Applications.

    Science.gov (United States)

    Kumar, Vishal; Dangi, Arun Kumar; Shukla, Pratyoosh

    2018-03-01

    Xylanases are one of the important hydrolytic enzymes which hydrolyze the β-1, 4 xylosidic linkage of the backbone of the xylan polymeric chain which consists of xylose subunits. Xylanases are mainly found in plant cell walls and are produced by several kinds of microorganisms such as fungi, bacteria, yeast, and some protozoans. The fungi are considered as most potent xylanase producers than that of yeast and bacteria. There is a broad series of industrial applications for the thermostable xylanase as an industrial enzyme. Thermostable xylanases have been used in a number of industries such as paper and pulp industry, biofuel industry, food and feed industry, textile industry, etc. The present review explores xylanase-substrate interactions using gene-editing tools toward the comprehension in improvement in industrial stability of xylanases. The various protein-engineering and metabolic-engineering methods have also been explored to improve operational stability of xylanase. Thermostable xylanases have also been used for improvement in animal feed nutritional value. Furthermore, they have been used directly in bakery and breweries, including a major use in paper and pulp industry as a biobleaching agent. This present review envisages some of such applications of thermostable xylanases for their bioengineering.

  6. Preparation of Laponite Bioceramics for Potential Bone Tissue Engineering Applications

    Science.gov (United States)

    Li, Kai; Ju, Yaping; Li, Jipeng; Zhang, Yongxing; Li, Jinhua; Liu, Xuanyong; Shi, Xiangyang; Zhao, Qinghua

    2014-01-01

    We report a facile approach to preparing laponite (LAP) bioceramics via sintering LAP powder compacts for bone tissue engineering applications. The sintering behavior and mechanical properties of LAP compacts under different temperatures, heating rates, and soaking times were investigated. We show that LAP bioceramic with a smooth and porous surface can be formed at 800°C with a heating rate of 5°C/h for 6 h under air. The formed LAP bioceramic was systematically characterized via different methods. Our results reveal that the LAP bioceramic possesses an excellent surface hydrophilicity and serum absorption capacity, and good cytocompatibility and hemocompatibility as demonstrated by resazurin reduction assay of rat mesenchymal stem cells (rMSCs) and hemolytic assay of pig red blood cells, respectively. The potential bone tissue engineering applicability of LAP bioceramic was explored by studying the surface mineralization behavior via soaking in simulated body fluid (SBF), as well as the surface cellular response of rMSCs. Our results suggest that LAP bioceramic is able to induce hydroxyapatite deposition on its surface when soaked in SBF and rMSCs can proliferate well on the LAP bioceramic surface. Most strikingly, alkaline phosphatase activity together with alizarin red staining results reveal that the produced LAP bioceramic is able to induce osteoblast differentiation of rMSCs in growth medium without any inducing factors. Finally, in vivo animal implantation, acute systemic toxicity test and hematoxylin and eosin (H&E)-staining data demonstrate that the prepared LAP bioceramic displays an excellent biosafety and is able to heal the bone defect. Findings from this study suggest that the developed LAP bioceramic holds a great promise for treating bone defects in bone tissue engineering. PMID:24955961

  7. Inductive learning as a fusion engine for mine detection

    Energy Technology Data Exchange (ETDEWEB)

    Kercel, S.W.; Dress, W.B.

    1997-08-01

    Semiotics is defined by some researchers as {open_quotes}the study of the appearance (visual or otherwise) meaning, and use of symbols and symbol systems.{close_quotes} Semiotic fusion of data from multiple sensory sources is a potential solution to the problem of landmine detection. This turns out to be significant, because notwithstanding the diversity of sensor technologies being used to attack the problem, there is no single effective landmine sensor technology. The only practical, general-purpose mine detector presently available is the trained dog. Most research into mine-detection technology seeds to emulate the dog`s seemingly uncanny abilities. An ideal data-fusion system would mimic animal reaction, with the brain`s perceptive power melding multiple sensory cues into an awareness of the size and location of a mine. Furthermore, the fusion process should be adaptive, with the skill at combining cues into awareness improving with experience. Electronic data-fusion systems reported in the countermine literature use conventional vector-based pattern recognition methods. Although neural nets are popular, they have never satisfactorily met the challenge. Despite years of investigation, nobody has ever found a vector space representation that reliably characterizes mine identity. This strongly suggests that the features have not been found because researchers have been looking for the wrong characteristics. It is worth considering that dogs probably do not represent data as mathematical number lists, but they almost certainly represent data via semiotic structures.

  8. Engineering of an Extreme Rainfall Detection System using Grid Computing

    Directory of Open Access Journals (Sweden)

    Olivier Terzo

    2012-10-01

    Full Text Available This paper describes a new approach for intensive rainfall data analysis. ITHACA's Extreme Rainfall Detection System (ERDS is conceived to provide near real-time alerts related to potential exceptional rainfalls worldwide, which can be used by WFP or other humanitarian assistance organizations to evaluate the event and understand the potentially floodable areas where their assistance is needed. This system is based on precipitation analysis and it uses rainfall data from satellite at worldwide extent. This project uses the Tropical Rainfall Measuring Mission Multisatellite Precipitation Analysis dataset, a NASA-delivered near real-time product for current rainfall condition monitoring over the world. Considering the great deal of data to process, this paper presents an architectural solution based on Grid Computing techniques. Our focus is on the advantages of using a distributed architecture in terms of performances for this specific purpose.

  9. CAD/CAM/CAI Application for High-Precision Machining of Internal Combustion Engine Pistons

    Directory of Open Access Journals (Sweden)

    V. V. Postnov

    2014-07-01

    Full Text Available CAD/CAM/CAI application solutions for internal combustion engine pistons machining was analyzed. Low-volume technology of internal combustion engine pistons production was proposed. Fixture for CNC turning center was designed.

  10. State of radiotracer application at the Division of Environmental Engineering, CDTN, NUCLEBRAS

    International Nuclear Information System (INIS)

    Aun, P.E.; Castro, J.O.N.M. de; Moreira, R.M.; Bandeira, J.V.

    1984-01-01

    The history and working phylosophy of the NUCLEBRAS division of environmental engineering are reported. Some aspects of tracer applications and of the tasks performed by the division of environmental engineering are described. (M.A.C.) [pt

  11. Application of stem cells in tissue engineering for defense medicine.

    Science.gov (United States)

    Ude, Chinedu Cletus; Miskon, Azizi; Idrus, Ruszymah Bt Hj; Abu Bakar, Muhamad Bin

    2018-02-26

    The dynamic nature of modern warfare, including threats and injuries faced by soldiers, necessitates the development of countermeasures that address a wide variety of injuries. Tissue engineering has emerged as a field with the potential to provide contemporary solutions. In this review, discussions focus on the applications of stem cells in tissue engineering to address health risks frequently faced by combatants at war. Human development depends intimately on stem cells, the mysterious precursor to every kind of cell in the body that, with proper instruction, can grow and differentiate into any new tissue or organ. Recent reports have suggested the greater therapeutic effects of the anti-inflammatory, trophic, paracrine and immune-modulatory functions associated with these cells, which induce them to restore normal healing and tissue regeneration by modulating immune reactions, regulating inflammation, and suppressing fibrosis. Therefore, the use of stem cells holds significant promise for the treatment of many battlefield injuries and their complications. These applications include the treatment of injuries to the skin, sensory organs, nervous system tissues, the musculoskeletal system, circulatory/pulmonary tissues and genitals/testicles and of acute radiation syndrome and the development of novel biosensors. The new research developments in these areas suggest that solutions are being developed to reduce critical consequences of wounds and exposures suffered in warfare. Current military applications of stem cell-based therapies are already saving the lives of soldiers who would have died in previous conflicts. Injuries that would have resulted in deaths previously now result in wounds today; similarly, today's permanent wounds may be reduced to tomorrow's bad memories with further advances in stem cell-based therapies.

  12. Tissue Engineering Applications of Three-Dimensional Bioprinting.

    Science.gov (United States)

    Zhang, Xiaoying; Zhang, Yangde

    2015-07-01

    Recent advances in tissue engineering have adapted the additive manufacturing technology, also known as three-dimensional printing, which is used in several industrial applications, for the fabrication of bioscaffolds and viable tissue and/or organs to overcome the limitations of other in vitro conventional methods. 3D bioprinting technology has gained enormous attention as it enabled 3D printing of a multitude of biocompatible materials, different types of cells and other supporting growth factors into complex functional living tissues in a 3D format. A major advantage of this technology is its ability for simultaneously 3D printing various cell types in defined spatial locations, which makes this technology applicable to regenerative medicine to meet the need for suitable for transplantation suitable organs and tissues. 3D bioprinting is yet to successfully overcome the many challenges related to building 3D structures that closely resemble native organs and tissues, which are complex structures with defined microarchitecture and a variety of cell types in a confined area. An integrated approach with a combination of technologies from the fields of engineering, biomaterials science, cell biology, physics, and medicine is required to address these complexities. Meeting this challenge is being made possible by directing the 3D bioprinting to manufacture biomimetic-shaped 3D structures, using organ/tissue images, obtained from magnetic resonance imaging and computerized tomography, and employing computer-aided design and manufacturing technologies. Applications of 3D bioprinting include the generation of multilayered skin, bone, vascular grafts, heart valves, etc. The current 3D bioprinting technologies need to be improved with respect to the mechanical strength and integrity in the manufactured constructs as the presently used biomaterials are not of optimal viscosity. A better understanding of the tissue/organ microenvironment, which consists of multiple types of

  13. Detection of Cast Shadows in Surveillance Applications

    DEFF Research Database (Denmark)

    Erbou, Søren G.; Sørensen, Helge Bjarne Dissing; Stage, Bjarne

    2005-01-01

    Cast shadows from moving objects reduce the general ability of robust classification and tracking of these objects, in outdoor surveillance applications. A method for segmentation of cast shadows is proposed, combining statistical features with a new similarity feature, derived from a physics...

  14. Advantages and Disadvantages of Using MATLAB/ode45 for Solving Differential Equations in Engineering Applications

    OpenAIRE

    Waleed K. Ahmed

    2013-01-01

    The present paper demonstrates the route used for solving differential equations for the engineering applications at UAEU. Usually students at the Engineering Requirements Unit (ERU) stage of the Faculty of Engineering at the UAEU must enroll in a course of Differential Equations and Engineering Applications (MATH 2210) as a prerequisite for the subsequent stages of their study. Mainly, one of the objectives of this course is that the students practice MATLAB software package during the cours...

  15. Application of image editing software for forensic detection of image ...

    African Journals Online (AJOL)

    Application of image editing software for forensic detection of image. ... The image editing software's available today is apt for creating visually compelling and sophisticated fake images, ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT

  16. Civil Engineering Applications of Ground Penetrating Radar in Finland

    Science.gov (United States)

    Pellinen, Terhi; Huuskonen-Snicker, Eeva; Olkkonen, Martta-Kaisa; Eskelinen, Pekka

    2014-05-01

    Ground penetrating radar (GPR) has been used in Finland since 1980's for civil engineering applications. First applications in this field were road surveys and dam inspections. Common GPR applications in road surveys include the thickness evaluation of the pavement, subgrade soil evaluation and evaluation of the soil moisture and frost susceptibility. Since the 1990's, GPR has been used in combination with other non-destructive testing (NDT) methods in road surveys. Recently, more GPR applications have been adopted, such as evaluating bridges, tunnels, railways and concrete elements. Nowadays, compared with other countries GPR is relatively widely used in Finland for road surveys. Quite many companies, universities and research centers in Finland have their own GPR equipment and are involved in the teaching and research of the GPR method. However, further research and promotion of the GPR techniques are still needed since GPR could be used more routinely. GPR has been used to evaluate the air void content of asphalt pavements for years. Air void content is an important quality measure of pavement condition for both the new and old asphalt pavements. The first Finnish guideline was released in 1999 for the method. Air void content is obtained from the GPR data by measuring the dielectric value as continuous record. To obtain air void content data, few pavement cores must be taken for calibration. Accuracy of the method is however questioned because there are other factors that affect the dielectric value of the asphalt layer, in addition to the air void content. Therefore, a research project is currently carried out at Aalto University in Finland. The overall objective is to investigate if the existing GPR technique used in Finland is accurate enough to be used as QC/QA tool in assessing the compaction of asphalt pavements. The project is funded by the Finnish Transport Agency. Further research interests at Aalto University include developing new microwave asphalt

  17. Plastic Gamma Sensors: An Application in Detection of Radioisotopes

    International Nuclear Information System (INIS)

    Mukhopadhyay, S.

    2003-01-01

    A brief survey of plastic scintillators for various radiation measurement applications is presented here. The utility of plastic scintillators for practical applications such as gamma radiation monitoring, real-time radioisotope detection and screening is evaluated in laboratory and field measurements. This study also reports results of Monte Carlo-type predictive responses of common plastic scintillators in gamma and neutron radiation fields. Small-size plastic detectors are evaluated for static and dynamic gamma-ray detection sensitivity of selected radiation sources

  18. Application of Crushed Concrete in Geotechnical Engineering - Selected Issues

    Science.gov (United States)

    Kawalec, Jacek; Kwiecien, Slawomir; Pilipenko, Anton; Rybak, Jarosław

    2017-12-01

    The reuse of building materials becomes an important issue in sustainable engineering. As the technical requirements for civil engineering structures changes with time and the life time is limited, the need of building new objects meets the necessity of recycling of the existing ones. In the case of steel structures, the possibility of recycling is obvious, also in the case of wooden constructions, the possibility of “burning” solves the problem. The concrete waste is generated mainly as a result of the demolition and reconstruction of residential and industrial buildings. These types of waste are basically made from crushed rocks and cement minerals and contain non-hydrated cement particles in its composition. Concrete poses a lot of problems mainly for two reasons. It is difficult to crush, heavy and hard to transport and demanding in reuse. Different fractions (particle sizes) may be used for different purposes. Starting from very fine particles which can be used in concrete production, through regular 16-300 mm fractions used to form new fills and fill the mats, up to very irregular mixtures used to form stone columns by means of Impulse Compaction or in Dynamic Replacement. The presented study juxtaposes authors experience with crushed concrete used in civil engineering, mainly in geotechnical projects. Authors’ experiences comprise the application of crushed concrete in the new concrete production in Russia, changing pulverized bridge into the fill of mesh sacks, or mattresses used as an effective way to protect the shoreline and the New Orleans East land bridge after Katrina storm (forming a new shoreline better able to withstand wave actions), and finally the use of very irregular concrete fractions to form stone columns in week soils on the example of railway and road projects in Poland. Selected case studies are presented and summarized with regard to social, technical and economic issues including energy consumption needed for proposed technologies

  19. Multifunctional silk-heparin biomaterials for vascular tissue engineering applications

    Science.gov (United States)

    Seib, F. Philipp; Herklotz, Manuela; Burke, Kelly A.; Maitz, Manfred F.; Werner, Carsten; Kaplan, David L.

    2013-01-01

    Over the past 30 years, silk has been proposed for numerous biomedical applications that go beyond its traditional use as a suture material. Silk sutures are well tolerated in humans, but the use of silk for vascular engineering applications still requires extensive biocompatibility testing. Some studies have indicated a need to modify silk to yield a hemocompatible surface. This study examined the potential of low molecular weight heparin as a material for refining silk properties by acting as a carrier for vascular endothelial growth factor (VEGF) and improving silk hemocompatibility. Heparinized silk showed a controlled VEGF release over 6 days; the released VEGF was bioactive and supported the growth of human endothelial cells. Silk samples were then assessed using a humanized hemocompatibility system that employs whole blood and endothelial cells. The overall thrombogenic response for silk was very low and similar to the clinical reference material polytetrafluoroethylene. Despite an initial inflammatory response to silk, apparent as complement and leukocyte activation, the endothelium was maintained in a resting, anticoagulant state. The low thrombogenic response and the ability to control VEGF release support the further development of silk for vascular applications. PMID:24099708

  20. Microscale Bioadhesive Hydrogel Arrays for Cell Engineering Applications

    Science.gov (United States)

    PATEL, RAVI GHANSHYAM; PURWADA, ALBERTO; CERCHIETTI, LEANDRO; INGHIRAMI, GIORGIO; MELNICK, ARI; GAHARWAR, AKHILESH K.; SINGH, ANKUR

    2014-01-01

    Bioengineered hydrogels have been explored in cell and tissue engineering applications to support cell growth and modulate its behavior. A rationally designed scaffold should allow for encapsulated cells to survive, adhere, proliferate, remodel the niche, and can be used for controlled delivery of biomolecules. Here we report a microarray of composite bioadhesive microgels with modular dimensions, tunable mechanical properties and bulk modified adhesive biomolecule composition. Composite bioadhesive microgels of maleimide functionalized polyethylene glycol (PEG-MAL) with interpenetrating network (IPN) of gelatin ionically cross-linked with silicate nanoparticles were engineered by integrating microfabrication with Michael-type addition chemistry and ionic gelation. By encapsulating clinically relevant anchorage-dependent cervical cancer cells and suspension leukemia cells as cell culture models in these composite microgels, we demonstrate enhanced cell spreading, survival, and metabolic activity compared to control gels. The composite bioadhesive hydrogels represent a platform that could be used to study independent effect of stiffness and adhesive ligand density on cell survival and function. We envision that such microarrays of cell adhesive microenvironments, which do not require harsh chemical and UV crosslinking conditions, will provide a more efficacious cell culture platform that can be used to study cell behavior and survival, function as building blocks to fabricate 3D tissue structures, cell delivery systems, and high throughput drug screening devices. PMID:25328548

  1. Renewable energy technology from underpinning physics to engineering application

    International Nuclear Information System (INIS)

    Infield, D G

    2008-01-01

    The UK Energy Research Centre (UKERC) in it's submission to the DTI's 2006 Energy Review reminded us that the 'UK has abundant wind, wave and tidal resources available; its mild climate lends itself to bio-energy production, and solar radiation levels are sufficient to sustain a viable solar industry'. These technologies are at different stages of development but they all draw on basic and applied Science and Engineering. The paper will briefly review the renewable energy technologies and their potential for contributing to a sustainable energy supply. Three research topics will be highlighted that bridge the gap between the physics underpinning the energy conversion, and the engineering aspects of development and deployment; all three are highly relevant to the Government's programme on micro-generation. Two are these are taken from field of thin film photovoltaics (PV), one related to novel device development and the other to a measurement technique for assessing the manufacturing quality of PV modules and their performance. The third topic concerns the development of small building integrated wind turbines and examines the complex flow associated with such applications. The paper will conclude by listing key research challenges that are central to the search for efficient and cost-effective renewable energy generation

  2. Practical application of reliability engineering in detailed design and maintenance

    International Nuclear Information System (INIS)

    Barden, S.E.

    1975-01-01

    Modern plant systems are closely coupled combinations of sophisticated and expensive equipment, some important parts of which may be in the development stage (high technology sector), and simpler, crude but not necessarily cheap equipment (low technology sector). Manpower resources involved with such plant systems can also be placed in high and low technology categories (i.e. specialist design and construction staff, and production staff, respectively). Neither can operate effectively without the other, and both are equally important. A sophisticated on-line computer controlling plant or analysing fault symptoms is useless, if not unsafe, if the peripheral sensing and control equipment on plant providing input data is poorly designed and inaccurate, and/or unreliable because of inadequate maintenance. Similarly, the designer can be misled and misinformed, and subsequent design evolution can be wrongly directed, if production recors do not accurately reflect what is actually happening on the plant. The application of Reliability Technology can be counter productive if it demands more effort in the collection of data that it save in facilitating quick, correct engineering decisions, and more accurate assessments of resource requirements. Reliability Engineering techniques must be simplified to made their use widely adopted in the important low technology sector, and established in all financial and contractural procedures associated with design specification and production management. This paper develops this theme with practical examples. (author)

  3. Engineering derivatives from biological systems for advanced aerospace applications

    Science.gov (United States)

    Winfield, Daniel L.; Hering, Dean H.; Cole, David

    1991-01-01

    The present study consisted of a literature survey, a survey of researchers, and a workshop on bionics. These tasks produced an extensive annotated bibliography of bionics research (282 citations), a directory of bionics researchers, and a workshop report on specific bionics research topics applicable to space technology. These deliverables are included as Appendix A, Appendix B, and Section 5.0, respectively. To provide organization to this highly interdisciplinary field and to serve as a guide for interested researchers, we have also prepared a taxonomy or classification of the various subelements of natural engineering systems. Finally, we have synthesized the results of the various components of this study into a discussion of the most promising opportunities for accelerated research, seeking solutions which apply engineering principles from natural systems to advanced aerospace problems. A discussion of opportunities within the areas of materials, structures, sensors, information processing, robotics, autonomous systems, life support systems, and aeronautics is given. Following the conclusions are six discipline summaries that highlight the potential benefits of research in these areas for NASA's space technology programs.

  4. A review of free-piston engine history and applications

    Energy Technology Data Exchange (ETDEWEB)

    Mikalsen, R.; Roskilly, A.P. [School of Marine Science and Technology, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU (United Kingdom)

    2007-10-15

    This document reviews the history of free-piston internal combustion engines, from the air compressors and gas generators used in the mid-20th century through to recent free-piston hydraulic engines and linear electric generators. Unique features of the free-piston engine are presented and their effects on engine operation are discussed, along with potential advantages and disadvantages compared to conventional engines. The paper focuses mainly on developed engines where operational data has been reported. Finally, the potential of the free-piston engine is evaluated and the most promising designs identified. (author)

  5. Application of Product Configuration Systems in Engineering Companies

    DEFF Research Database (Denmark)

    Kristjansdottir, Katrin

    Engineering companies increasingly face the challenge of delivering highly customized products where time, cost, and quality are critical factors. To provide customized products efficiently, a product configuration system (PCS) is commonly implemented. A PCS supports the product configuration...... process, which consists of activities that involve gathering requirements from customers and generating the required product-related specifications. The application of a PCS in the industry has revealed benefits that include shorter lead-times, improved quality of specifications and products, and lower...... overall cost of the product. However, many PCS projects do encounter failure. With an increased focus on customized and personalized products, there is a growing need for the automation of business processes. For this reason, a PCS is becoming an essential part of IT strategy in different industries...

  6. Idaho National Engineering Laboratory irradiation facilities and their applications

    International Nuclear Information System (INIS)

    Gupta, V.P.; Herring, J.S.; Korenke, R.E.; Harker, Y.D.

    1986-05-01

    Although there is a growing need for neutron and gamma irradiation by governmental and industrial organizations in the United States and in other countries, the number of facilities providing such irradiations are limited. At the Idaho National Engineering Laboratory, there are several unique irradiation facilities producing high neutron and gamma radiation environments. These facilities could be readily used for nuclear research, materials testing, radiation hardening studies on electronic components/circuitry and sensors, and production of neutron transmutation doped (NTD) silicon and special radioisotopes. In addition, a neutron radiography unit, suitable for examining irradiated materials and assemblies, is also available. This report provides a description of the irradiation facilities and the neutron radiography unit as well as examples of their unique applications

  7. 2nd International Conference on Advanced Engineering : Theory and Applications

    CERN Document Server

    Dao, Tran; Zelinka, Ivan; Choi, Hyeung-Sik; Chadli, Mohammed

    2016-01-01

    This proceeding book consists of 10 topical areas of selected papers like: telecommunication, power systems, robotics, control system, renewable energy, power electronics, computer science and more. All selected papers represent interesting ideas and state of the art overview. Readers will find interesting papers of those areas about design and implement of dynamic positioning control system for USV, scheduling problems, motor control, backtracking search algorithm for distribution network and others. All selected papers represent interesting ideas and state of art overview. The proceeding book will also be a resource and material for practitioners who want to apply discussed problems to solve real-life problems in their challenging applications. It is also devoted to the studies of common and related subjects in intensive research fields of modern electric, electronic and related technologies. For these reasons, we believe that this proceeding book will be useful for scientists and engineers working in the ...

  8. Computer graphics application in the engineering design integration system

    Science.gov (United States)

    Glatt, C. R.; Abel, R. W.; Hirsch, G. N.; Alford, G. E.; Colquitt, W. N.; Stewart, W. A.

    1975-01-01

    The computer graphics aspect of the Engineering Design Integration (EDIN) system and its application to design problems were discussed. Three basic types of computer graphics may be used with the EDIN system for the evaluation of aerospace vehicles preliminary designs: offline graphics systems using vellum-inking or photographic processes, online graphics systems characterized by direct coupled low cost storage tube terminals with limited interactive capabilities, and a minicomputer based refresh terminal offering highly interactive capabilities. The offline line systems are characterized by high quality (resolution better than 0.254 mm) and slow turnaround (one to four days). The online systems are characterized by low cost, instant visualization of the computer results, slow line speed (300 BAUD), poor hard copy, and the early limitations on vector graphic input capabilities. The recent acquisition of the Adage 330 Graphic Display system has greatly enhanced the potential for interactive computer aided design.

  9. Introduction to computational mass transfer with applications to chemical engineering

    CERN Document Server

    Yu, Kuo-Tsong

    2014-01-01

    This book presents a new computational methodology called Computational Mass Transfer (CMT). It offers an approach to rigorously simulating the mass, heat and momentum transfer under turbulent flow conditions with the help of two newly published models, namely the C’2—εC’ model and the Reynolds  mass flux model, especially with regard to predictions of concentration, temperature and velocity distributions in chemical and related processes. The book will also allow readers to understand the interfacial phenomena accompanying the mass transfer process and methods for modeling the interfacial effect, such as the influences of Marangoni convection and Rayleigh convection. The CMT methodology is demonstrated by means of its applications to typical separation and chemical reaction processes and equipment, including distillation, absorption, adsorption and chemical reactors. Professor Kuo-Tsong Yu is a Member of the Chinese Academy of Sciences. Dr. Xigang Yuan is a Professor at the School of Chemical Engine...

  10. Monte Carlo applications at Hanford Engineering Development Laboratory

    International Nuclear Information System (INIS)

    Carter, L.L.; Morford, R.J.; Wilcox, A.D.

    1980-03-01

    Twenty applications of neutron and photon transport with Monte Carlo have been described to give an overview of the current effort at HEDL. A satisfaction factor was defined which quantitatively assigns an overall return for each calculation relative to the investment in machine time and expenditure of manpower. Low satisfaction factors are frequently encountered in the calculations. Usually this is due to limitations in execution rates of present day computers, but sometimes a low satisfaction factor is due to computer code limitations, calendar time constraints, or inadequacy of the nuclear data base. Present day computer codes have taken some of the burden off of the user. Nevertheless, it is highly desirable for the engineer using the computer code to have an understanding of particle transport including some intuition for the problems being solved, to understand the construction of sources for the random walk, to understand the interpretation of tallies made by the code, and to have a basic understanding of elementary biasing techniques

  11. Application of GIS in hydrogeology and engineering geology

    Directory of Open Access Journals (Sweden)

    Lucia Mihalová

    2007-06-01

    Full Text Available Hydrogeology as a specific science discipline has a multi spectral interest focused to officiating sources in drink water and utilization water and also in area aimed for pure mineral water sources. Although engineering geology works exercise with piece of knowledge, geosciences are focused to territorial planning, investment construction and protection environment. Application of GIS in appointed problems purvey possibility quality, quick and high special analysis appointed problems and take advantage all accessible quality and quantity related information of water focused to hydrogeology, as to occurrence varied basement soil, appropriate for building activity, possibly appointed for protection. Solution of this probleme is on first name terms definite interest area, as to adjudication sources focused economic significance state.

  12. Practical application of computer graphics in nuclear power plant engineering

    International Nuclear Information System (INIS)

    Machiba, Hiroshi; Kawamura, Hirobumi; Sasaki, Norio

    1992-01-01

    A nuclear power plant is composed of a vast amount of equipment, piping, and so on, and six or seven years are required to complete the design and engineering from the initial planning stage to the time of commercial operation. Furthermore, operating plants must be continually maintained and improved for a long period. Computer graphics were first applied to the composite arrangement design of nuclear power plants in the form of 3-dimensional CAD. Subsequently, as the introduction of CAE has progressed, a huge assortment of information has been accumulated in database, and measures have been sought that would permit the convenient utilization of this information. Using computer graphics technologies, improvement of the interface between the user and such databases has recently been accomplished. In response to the growth in environmental consciousness, photo-realistic simulations for artistic design of the interior and overviews showing harmony with the surroundings have been achieved through the application of computer graphics. (author)

  13. Strong terahertz field generation, detection, and application

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Yong [Univ. of Maryland, College Park, MD (United States)

    2016-05-22

    This report describes the generation and detection of high-power, broadband terahertz (THz) radiation with using femtosecond terawatt (TW) laser systems. In particular, this focuses on two-color laser mixing in gases as a scalable THz source, addressing both microscopic and macroscopic effects governing its output THz yield and radiation profile. This also includes the characterization of extremely broad THz spectra extending from microwaves to infrared frequencies. Experimentally, my group has generated high-energy (tens of microjoule), intense (>8 MV/cm), and broadband (0.01~60 THz) THz radiation in two-color laser mixing in air. Such an intense THz field can be utilized to study THz-driven extremely nonlinear phenomena in a university laboratory.

  14. Strong terahertz field generation, detection, and application

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ki-Yong [Univ. of Maryland, College Park, MD (United States)

    2016-05-15

    This report describes the generation and detection of high-power, broadband terahertz (THz) radiation with using femtosecond terawatt (TW) laser systems. In particular, this focuses on two-color laser mixing in gases as a scalable THz source, addressing both microscopic and macroscopic effects governing its output THz yield and radiation profile. This also includes the characterization of extremely broad THz spectra extending from microwaves to infrared frequencies. Experimentally, my group has generated high-energy (tens of microjoule), intense (>8 MV/cm), and broadband (0.01~60 THz) THz radiation in two-color laser mixing in air. Such an intense THz field can be utilized to study THz-driven extremely nonlinear phenomena in a university laboratory.

  15. Smartphone application for emergency signal detection.

    Science.gov (United States)

    Figueiredo, Isabel N; Leal, Carlos; Pinto, Luís; Bolito, Jason; Lemos, André

    2016-09-01

    Currently, a number of studies focus on the study and design of new healthcare technologies to improve elderly health and quality of life. Taking advantage of the popularity, portability, and inherent technology of smartphones, we present an emergency application for smartphones, designated as knock-to-panic (KTP). This innovative and novel system enables users to simply hit their devices in order to send an alarm signal to an emergency service. This application is a complete and autonomous emergency system, and can provide an economic, reliable, and unobtrusive method for elderly monitoring or safety protection. Moreover, the simple and fast activation of KTP makes it a viable and potentially superior alternative to traditional ambient assisted living emergency calls. Furthermore, KTP can be further extended to the general population as well and not just be limited for elderly persons. The proposed method is a threshold-based algorithm and is designed to require a low battery power consumption. The evaluation of the performance of the algorithm in collected data indicates that both sensitivity and specificity are above 90%. Copyright © 2016 IPEM. Published by Elsevier Ltd. All rights reserved.

  16. Genetically Engineered Virulent Phage Banks in the Detection and Control of Emergent Pathogenic Bacteria

    Science.gov (United States)

    Blois, Hélène; Iris, François

    2010-01-01

    Natural outbreaks of multidrug-resistant microorganisms can cause widespread devastation, and several can be used or engineered as agents of bioterrorism. From a biosecurity standpoint, the capacity to detect and then efficiently control, within hours, the spread and the potential pathological effects of an emergent outbreak, for which there may be no effective antibiotics or vaccines, become key challenges that must be met. We turned to phage engineering as a potentially highly flexible and effective means to both detect and eradicate threats originating from emergent (uncharacterized) bacterial strains. To this end, we developed technologies allowing us to (1) concurrently modify multiple regions within the coding sequence of a gene while conserving intact the remainder of the gene, (2) reversibly interrupt the lytic cycle of an obligate virulent phage (T4) within its host, (3) carry out efficient insertion, by homologous recombination, of any number of engineered genes into the deactivated genomes of a T4 wild-type phage population, and (4) reactivate the lytic cycle, leading to the production of engineered infective virulent recombinant progeny. This allows the production of very large, genetically engineered lytic phage banks containing, in an E. coli host, a very wide spectrum of variants for any chosen phage-associated function, including phage host-range. Screening of such a bank should allow the rapid isolation of recombinant T4 particles capable of detecting (ie, diagnosing), infecting, and destroying hosts belonging to gram-negative bacterial species far removed from the original E. coli host. PMID:20569057

  17. Diesel engine coolant analysis, new application for established instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, D P; Lukas, M; Lynch, B K [Spectro Incorporated, Littleton, MA (United States)

    1998-12-31

    Rotating disk electrode (RDE) arc emission spectrometers are user` many commercial, industrial and military laboratories throughout the world to analyze millions of oil and fuel samples each year. In fact, RDE spectrometers have been used exclusively for oil and fuel analysis for so long that it has nearly been forgotten by most practitioners that when RDE spectrometers were first introduced more than 40 years ago, they were routinely used for aqueous samples as well. This presentation reviews early methods of aqueous sample analysis using RDE technology. This presentation also describes recent work to calibrate an RDE spectrometer for both water samples and for engine coolant samples which are a mixture of approximately 50 % water and 50 % ethylene or propylene glycol. Limits of detection determined for aqueous standards are comparable to limits of detection for oil standards. Repeatability of aqueous samples is comparable to the repeatability achieved for oil samples. A comparison of results for coolant samples measured by both inductively coupled plasma (ICP) and rotating disk electrode (RDE) spectrometers is presented. Not surprisingly, RDE results are significantly higher for samples containing particles larger than a few micrometers. Although limits of detection for aqueous samples are not as low as can be achieved using the more modern ICP spectrometric method or the more cumbersome atomic absorption (AA) method, this presentation suggests that RDE spectrometers may be appropriate for certain types of aqueous samples in situations where the more sensitive ICP or AA spectrometers and the laboratory environment and skilled personnel needed for them to operate are not conveniently available. (orig.) 4 refs.

  18. Diesel engine coolant analysis, new application for established instrumentation

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, D.P.; Lukas, M.; Lynch, B.K. [Spectro Incorporated, Littleton, MA (United States)

    1997-12-31

    Rotating disk electrode (RDE) arc emission spectrometers are user` many commercial, industrial and military laboratories throughout the world to analyze millions of oil and fuel samples each year. In fact, RDE spectrometers have been used exclusively for oil and fuel analysis for so long that it has nearly been forgotten by most practitioners that when RDE spectrometers were first introduced more than 40 years ago, they were routinely used for aqueous samples as well. This presentation reviews early methods of aqueous sample analysis using RDE technology. This presentation also describes recent work to calibrate an RDE spectrometer for both water samples and for engine coolant samples which are a mixture of approximately 50 % water and 50 % ethylene or propylene glycol. Limits of detection determined for aqueous standards are comparable to limits of detection for oil standards. Repeatability of aqueous samples is comparable to the repeatability achieved for oil samples. A comparison of results for coolant samples measured by both inductively coupled plasma (ICP) and rotating disk electrode (RDE) spectrometers is presented. Not surprisingly, RDE results are significantly higher for samples containing particles larger than a few micrometers. Although limits of detection for aqueous samples are not as low as can be achieved using the more modern ICP spectrometric method or the more cumbersome atomic absorption (AA) method, this presentation suggests that RDE spectrometers may be appropriate for certain types of aqueous samples in situations where the more sensitive ICP or AA spectrometers and the laboratory environment and skilled personnel needed for them to operate are not conveniently available. (orig.) 4 refs.

  19. Preliminary Study on Acoustic Detection of Faults Experienced by a High-Bypass Turbofan Engine

    Science.gov (United States)

    Boyle, Devin K.

    2014-01-01

    The vehicle integrated propulsion research (VIPR) effort conducted by NASA and several partners provided an unparalleled opportunity to test a relatively low TRL concept regarding the use of far field acoustics to identify faults occurring in a high bypass turbofan engine. Though VIPR Phase II ground based aircraft installed engine testing wherein a multitude of research sensors and methods were evaluated, an array of acoustic microphones was used to determine the viability of such an array to detect failures occurring in a commercially representative high bypass turbofan engine. The failures introduced during VIPR testing included commanding the engine's low pressure compressor (LPC) exit and high pressure compressor (HPC) 14th stage bleed values abruptly to their failsafe positions during steady state

  20. Data mining approach to web application intrusions detection

    Science.gov (United States)

    Kalicki, Arkadiusz

    2011-10-01

    Web applications became most popular medium in the Internet. Popularity, easiness of web application script languages and frameworks together with careless development results in high number of web application vulnerabilities and high number of attacks performed. There are several types of attacks possible because of improper input validation: SQL injection Cross-site scripting, Cross-Site Request Forgery (CSRF), web spam in blogs and others. In order to secure web applications intrusion detection (IDS) and intrusion prevention systems (IPS) are being used. Intrusion detection systems are divided in two groups: misuse detection (traditional IDS) and anomaly detection. This paper presents data mining based algorithm for anomaly detection. The principle of this method is the comparison of the incoming HTTP traffic with a previously built profile that contains a representation of the "normal" or expected web application usage sequence patterns. The frequent sequence patterns are found with GSP algorithm. Previously presented detection method was rewritten and improved. Some tests show that the software catches malicious requests, especially long attack sequences, results quite good with medium length sequences, for short length sequences must be complemented with other methods.

  1. Nitric oxide in a diesel engine. Laser-based detection and interpretation

    International Nuclear Information System (INIS)

    Stoffels, G.G.M.

    1999-01-01

    The main objective of the work described in this thesis is the development of a method to determine the nitric oxide (NO) density with both spatial and temporal resolution during the combustion inside the cylinder of a diesel engine by means of laser diagnostics. As a tool to observe the NO molecules the Laser Induced Fluorescence (LIF) technique is used. This non-intrusive technique allows to detect minority species in combustion with spatial and temporal resolution. The intensity of the fluorescence resulting from the NO molecules, that are excited by the laser radiation is a measure for the amount of NO present in the cylinder of the running engine. The engine used is a one-cylinder, two-stroke, direct injection diesel engine. The engine is made optically accessible by mounting two quartz windows in the cylinder wall through which the laser beam can traverse the combustion chamber. A third window is placed in the centre of the cylinder head and is used to detect the fluorescence. The engine was operated in steady-state, on standard commercial diesel fuel and non-oxygen enriched intake air, in contrast to most other experiments reported in literature. In previously described experiments the research engine was mostly operated in skip-fired mode on a substitute fuel and often extra oxygen was supplied to the intake air. The experiments reported in this thesis have shown that it is possible to observe NO inside the combustion chamber of the two-stroke diesel engine applying the LIF technique. 93 refs

  2. ZnO Nanostructures for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Marco Laurenti

    2017-11-01

    Full Text Available This review focuses on the most recent applications of zinc oxide (ZnO nanostructures for tissue engineering. ZnO is one of the most investigated metal oxides, thanks to its multifunctional properties coupled with the ease of preparing various morphologies, such as nanowires, nanorods, and nanoparticles. Most ZnO applications are based on its semiconducting, catalytic and piezoelectric properties. However, several works have highlighted that ZnO nanostructures may successfully promote the growth, proliferation and differentiation of several cell lines, in combination with the rise of promising antibacterial activities. In particular, osteogenesis and angiogenesis have been effectively demonstrated in numerous cases. Such peculiarities have been observed both for pure nanostructured ZnO scaffolds as well as for three-dimensional ZnO-based hybrid composite scaffolds, fabricated by additive manufacturing technologies. Therefore, all these findings suggest that ZnO nanostructures represent a powerful tool in promoting the acceleration of diverse biological processes, finally leading to the formation of new living tissue useful for organ repair.

  3. Applications of Chondrocyte-Based Cartilage Engineering: An Overview

    Directory of Open Access Journals (Sweden)

    Abdul-Rehman Phull

    2016-01-01

    Full Text Available Chondrocytes are the exclusive cells residing in cartilage and maintain the functionality of cartilage tissue. Series of biocomponents such as different growth factors, cytokines, and transcriptional factors regulate the mesenchymal stem cells (MSCs differentiation to chondrocytes. The number of chondrocytes and dedifferentiation are the key limitations in subsequent clinical application of the chondrocytes. Different culture methods are being developed to overcome such issues. Using tissue engineering and cell based approaches, chondrocytes offer prominent therapeutic option specifically in orthopedics for cartilage repair and to treat ailments such as tracheal defects, facial reconstruction, and urinary incontinence. Matrix-assisted autologous chondrocyte transplantation/implantation is an improved version of traditional autologous chondrocyte transplantation (ACT method. An increasing number of studies show the clinical significance of this technique for the chondral lesions treatment. Literature survey was carried out to address clinical and functional findings by using various ACT procedures. The current study was conducted to study the pharmacological significance and biomedical application of chondrocytes. Furthermore, it is inferred from the present study that long term follow-up studies are required to evaluate the potential of these methods and specific positive outcomes.

  4. Engineering and Applications of fungal laccases for organic synthesis

    Directory of Open Access Journals (Sweden)

    Ballesteros Antonio

    2008-11-01

    Full Text Available Abstract Laccases are multi-copper containing oxidases (EC 1.10.3.2, widely distributed in fungi, higher plants and bacteria. Laccase catalyses the oxidation of phenols, polyphenols and anilines by one-electron abstraction, with the concomitant reduction of oxygen to water in a four-electron transfer process. In the presence of small redox mediators, laccase offers a broader repertory of oxidations including non-phenolic substrates. Hence, fungal laccases are considered as ideal green catalysts of great biotechnological impact due to their few requirements (they only require air, and they produce water as the only by-product and their broad substrate specificity, including direct bioelectrocatalysis. Thus, laccases and/or laccase-mediator systems find potential applications in bioremediation, paper pulp bleaching, finishing of textiles, bio-fuel cells and more. Significantly, laccases can be used in organic synthesis, as they can perform exquisite transformations ranging from the oxidation of functional groups to the heteromolecular coupling for production of new antibiotics derivatives, or the catalysis of key steps in the synthesis of complex natural products. In this review, the application of fungal laccases and their engineering by rational design and directed evolution for organic synthesis purposes are discussed.

  5. Ramgen Power Systems-Supersonic Component Technology for Military Engine Applications

    National Research Council Canada - National Science Library

    Sohn, Chang W; Holcomb, Franklin H; Baldwin, Peter; Lawlor, Shawn; Steele, Robert C; Belshaw, Karen; Tamm, Gunnar

    2006-01-01

    ...) a unique configuration that minimizes flow stream turning losses throughout the engine. The RPS engine concept can be configured as a high-pressure ratio simple-cycle design for propulsion applications or as a low-pressure ratio recuperated engine...

  6. Engineering models for merging wakes in wind farm optimization applications

    DEFF Research Database (Denmark)

    Machefaux, Ewan; Larsen, Gunner Chr.; Murcia Leon, Juan Pablo

    2015-01-01

    The present paper deals with validation of 4 different engineering wake superposition approaches against detailed CFD simulations and covering different turbine interspacing, ambient turbulence intensities and mean wind speeds. The first engineering model is a simple linear superposition of wake ...

  7. Detection and Elimination of a Potential Fire in Engine and Battery Compartments of Hybrid Electric Vehicles

    Directory of Open Access Journals (Sweden)

    Macam S. Dattathreya

    2012-01-01

    Full Text Available This paper presents a novel fuzzy deterministic noncontroller type (FDNCT system and an FDNCT inference algorithm (FIA. The FDNCT uses fuzzy inputs and produces a deterministic non-fuzzy output. The FDNCT is an extension and alternative for the existing fuzzy singleton inference algorithm. The research described in this paper applies FDNCT to build an architecture for an intelligent system to detect and to eliminate potential fires in the engine and battery compartments of a hybrid electric vehicle. The fuzzy inputs consist of sensor data from the engine and battery compartments, namely, temperature, moisture, and voltage and current of the battery. The system synthesizes the data and detects potential fires, takes actions for eliminating the hazard, and notifies the passengers about the potential fire using an audible alarm. This paper also presents the computer simulation results of the comparison between the FIA and singleton inference algorithms for detecting potential fires and determining the actions for eliminating them.

  8. Engineering Gold Nanorod-Based Plasmonic Nanocrystals for Optical Applications

    KAUST Repository

    Huang, Jianfeng

    2015-09-01

    Plasmonic nanocrystals have a unique ability to support localized surface plasmon resonances and exhibit rich and intriguing optical properties. Engineering plasmonic nanocrystals can maximize their potentials for specific applications. In this dissertation, we developed three unprecedented Au nanorod-based plasmonic nanocrystals through rational design of the crystal shape and/or composition, and successfully demonstrated their applications in light condensation, photothermal conversion, and surface-enhanced Raman spectroscopy (SERS). The “Au nanorod-Au nanosphere dimer” nanocrystal was synthesized via the ligand-induced asymmetric growth of a Au nanosphere on a Au nanorod. This dimeric nanostructure features an extraordinary broadband optical absorption in the range of 400‒1400nm, and it proved to be an ideal black-body material for light condensation and an efficient solar-light harvester for photothermal conversion. The “Au nanorod (core) @ AuAg alloy (shell)” nanocrystal was built through the epitaxial growth of homogeneously alloyed AuAg shells on Au nanorods by precisely controlled synthesis. The resulting core-shell structured, bimetallic nanorods integrate the merits of the AuAg alloy with the advantages of anisotropic nanorods, exhibiting strong, stable and tunable surface plasmon resonances that are essential for SERS applications in a corrosive environment. The “high-index faceted Au nanorod (core) @ AuPd alloy (shell)” nanocrystal was produced via site-specific epitaxial growth of AuPd alloyed horns at the ends of Au nanorods. The AuPd alloyed horns are bound with high-index side facets, while the Au nanorod concentrates an intensive electric field at each end. This unique configuration unites highly active catalytic sites with strong SERS sites into a single entity and was demonstrated to be ideal for in situ monitoring of Pd-catalyzed reactions by SERS. The synthetic strategies developed here are promising towards the fabrication of

  9. Alternatives to electrical cogeneration: The direct application of steam engines

    International Nuclear Information System (INIS)

    Phillips, W.C.

    1993-01-01

    Although small to medium sized industrial facilities are aware of electrical cogeneration, often they are too small for it to be economically justifiable. The direct application of steam turbine power to equipment formerly powered by electric motors, can allow them to use steam capacity to reduce electrical demand and consumption, bypassing cogeneration. Cogeneration converts the heat energy of steam into circular mechanical motion and then converts the circular mechanical motion into electricity. Each conversion entails a loss of energy due to friction and other conversion losses. A substantial amount of the generated electricity is then converted back into circular motion with electric motors, again incurring energy losses. Directly applying the mechanical motion of turbines eliminates both the motion-to-electricity (generator) and the electricity-to-motion (motor) conversion losses. Excess steam capacity during the summer is not unusual for facilities that use steam to provide winter heating. Similarly, most of these facilities experience a large electrical demand peak during the cooling season due to the electricity needed to operate centrifugal chillers. Steam capacity via a turbine to power the chillers can allow the boilers to operate at a higher loading while reducing electrical consumption and demand precisely those periods when demand reduction is most needed. In facilities where the steam generating capacity is sufficient, air compressors provide an appropriate year-round application for turbine power. This paper is the result of an on-going project by the Energy Division, State of North Carolina, Department of Economic and Community Development, in conjunction with the University of North Carolina at Charlotte. The objective of this project is to educate the operating engineers and managers of small to medium sized manufacturing facilities on the technical application and economic justification of steam turbine power

  10. A demonstration of expert systems applications in transportation engineering : volume I, transportation engineers and expert systems.

    Science.gov (United States)

    1987-01-01

    Expert systems, a branch of artificial-intelligence studies, is introduced with a view to its relevance in transportation engineering. Knowledge engineering, the process of building expert systems or transferring knowledge from human experts to compu...

  11. Application of nuclear photon engines for deep-space exploration

    International Nuclear Information System (INIS)

    Gulevich, Andrey V.; Ivanov, Eugeny A.; Kukharchuk, Oleg F.; Poupko, Victor Ya.; Zrodnikov, Anatoly V.

    2001-01-01

    Conception of using the nuclear photon rocket engines for deep space exploration is proposed. Some analytical estimations have been made to illustrate the possibility to travel to 100-10000 AU using a small thrust photon engine. Concepts of high temperature nuclear reactors for the nuclear photon engines are also discussed

  12. Building information modelling review with potential applications in tunnel engineering of China

    Science.gov (United States)

    Zhou, Weihong; Qin, Haiyang; Qiu, Junling; Fan, Haobo; Lai, Jinxing; Wang, Ke; Wang, Lixin

    2017-08-01

    Building information modelling (BIM) can be applied to tunnel engineering to address a number of problems, including complex structure, extensive design, long construction cycle and increased security risks. To promote the development of tunnel engineering in China, this paper combines actual cases, including the Xingu mountain tunnel and the Shigu Mountain tunnel, to systematically analyse BIM applications in tunnel engineering in China. The results indicate that BIM technology in tunnel engineering is currently mainly applied during the design stage rather than during construction and operation stages. The application of BIM technology in tunnel engineering covers many problems, such as a lack of standards, incompatibility of different software, disorganized management, complex combination with GIS (Geographic Information System), low utilization rate and poor awareness. In this study, through summary of related research results and engineering cases, suggestions are introduced and an outlook for the BIM application in tunnel engineering in China is presented, which provides guidance for design optimization, construction standards and later operation maintenance.

  13. Update of development on the new Audi NSU rotary engine generation. [for application to aircraft engines

    Science.gov (United States)

    Vanbasshuysen, R.

    1978-01-01

    Rotary engines with a chamber volume of 750 cc as a two rotor automotive powerplant, called KKM 871 are described. This engine is compared to a 3 liter or 183 cubic inch, six-cylinder reciprocating engine. Emphasis is placed on exhaust emission control and fuel economy.

  14. Detroit Diesel Engine Technology for Light Duty Truck Applications - DELTA Engine Update

    Energy Technology Data Exchange (ETDEWEB)

    Freese, Charlie

    2000-08-20

    The early generation of the DELTA engine has been thoroughly tested and characterized in the virtual lab, during engine dynamometer testing, and on light duty trucks for personal transportation. This paper provides an up-to-date account of program findings. Further, the next generation engine design and future program plans will be briefly presented.

  15. Anomaly Detection Based on Sensor Data in Petroleum Industry Applications

    Directory of Open Access Journals (Sweden)

    Luis Martí

    2015-01-01

    Full Text Available Anomaly detection is the problem of finding patterns in data that do not conform to an a priori expected behavior. This is related to the problem in which some samples are distant, in terms of a given metric, from the rest of the dataset, where these anomalous samples are indicated as outliers. Anomaly detection has recently attracted the attention of the research community, because of its relevance in real-world applications, like intrusion detection, fraud detection, fault detection and system health monitoring, among many others. Anomalies themselves can have a positive or negative nature, depending on their context and interpretation. However, in either case, it is important for decision makers to be able to detect them in order to take appropriate actions. The petroleum industry is one of the application contexts where these problems are present. The correct detection of such types of unusual information empowers the decision maker with the capacity to act on the system in order to correctly avoid, correct or react to the situations associated with them. In that application context, heavy extraction machines for pumping and generation operations, like turbomachines, are intensively monitored by hundreds of sensors each that send measurements with a high frequency for damage prevention. In this paper, we propose a combination of yet another segmentation algorithm (YASA, a novel fast and high quality segmentation algorithm, with a one-class support vector machine approach for efficient anomaly detection in turbomachines. The proposal is meant for dealing with the aforementioned task and to cope with the lack of labeled training data. As a result, we perform a series of empirical studies comparing our approach to other methods applied to benchmark problems and a real-life application related to oil platform turbomachinery anomaly detection.

  16. Remote sensing applications for transportation and traffic engineering studies: A review of the literature

    Science.gov (United States)

    Epps, J. W.

    1973-01-01

    Current references were surveyed for the application of remote sensing to traffic and transportation studies. The major problems are presented that concern traffic engineers and transportation managers, and the literature references that discuss remote sensing applications are summarized.

  17. Processing of Instantaneous Angular Speed Signal for Detection of a Diesel Engine Failure

    Directory of Open Access Journals (Sweden)

    Adam Charchalis

    2013-01-01

    Full Text Available Continuous monitoring of diesel engine performance under its operating is critical for the prediction of malfunction development and subsequently functional failure detection. Analysis of instantaneous angular speed (IAS of the crankshaft is considered as one of the nonintrusive and effective methods of the detection of combustion quality deterioration. In this paper results of experimental verification of fuel system's malfunction detecting, using optical encoder for IAS recording are presented. The implemented method relies on the comparison of measurement results, recorded under healthy and faulty conditions of the engine. Elaborated dynamic model of angular speed variations enables us to build templates of engine behavior. Recorded during experiment, values of cylinder pressure were taken for the approximation of pressure basic waveform. The main task of data processing is smoothing the raw angular speed signal. The noise is due to sensor mount vibrations, signal emitter machining, engine body vibrations, and crankshaft torsional vibrations. Smoothing of the measurement data was carried out by the implementation of the Savitzky-Golay filter. Measured signal after smoothing was compared with the model of IAS run.

  18. Data-driven fault detection, isolation and estimation of aircraft gas turbine engine actuator and sensors

    Science.gov (United States)

    Naderi, E.; Khorasani, K.

    2018-02-01

    In this work, a data-driven fault detection, isolation, and estimation (FDI&E) methodology is proposed and developed specifically for monitoring the aircraft gas turbine engine actuator and sensors. The proposed FDI&E filters are directly constructed by using only the available system I/O data at each operating point of the engine. The healthy gas turbine engine is stimulated by a sinusoidal input containing a limited number of frequencies. First, the associated system Markov parameters are estimated by using the FFT of the input and output signals to obtain the frequency response of the gas turbine engine. These data are then used for direct design and realization of the fault detection, isolation and estimation filters. Our proposed scheme therefore does not require any a priori knowledge of the system linear model or its number of poles and zeros at each operating point. We have investigated the effects of the size of the frequency response data on the performance of our proposed schemes. We have shown through comprehensive case studies simulations that desirable fault detection, isolation and estimation performance metrics defined in terms of the confusion matrix criterion can be achieved by having access to only the frequency response of the system at only a limited number of frequencies.

  19. Detecting and Characterizing Engineered Nanomaterials: A Key Tool for Environmentally Responsible Nanotechnology

    Science.gov (United States)

    The same properties of engineered nanomaterials (ENMs) that are the basis for their many novel applications also raise important issues related to their environmental impact. ENMs might not behave similarly in the environment to the dissolved or solid forms of the chemicals from ...

  20. Latest Progress of Fault Detection and Localization in Complex Electrical Engineering

    Science.gov (United States)

    Zhao, Zheng; Wang, Can; Zhang, Yagang; Sun, Yi

    2014-01-01

    In the researches of complex electrical engineering, efficient fault detection and localization schemes are essential to quickly detect and locate faults so that appropriate and timely corrective mitigating and maintenance actions can be taken. In this paper, under the current measurement precision of PMU, we will put forward a new type of fault detection and localization technology based on fault factor feature extraction. Lots of simulating experiments indicate that, although there are disturbances of white Gaussian stochastic noise, based on fault factor feature extraction principal, the fault detection and localization results are still accurate and reliable, which also identifies that the fault detection and localization technology has strong anti-interference ability and great redundancy.

  1. Applicability estimation of flowmeter logging for detecting hydraulic pass

    International Nuclear Information System (INIS)

    Miyakawa, Kimio; Tanaka, Yasuji; Tanaka, Kazuhiro

    1997-01-01

    Estimation of the hydraulic pass governing hydrogeological structure contributes significantly to the siting HLW repository. Flowmeter logging can detect hydraulic passes by measuring vertical flow velocity of groundwater in the borehole. We reviewed application of this logging in situ. The hydraulic pass was detected with combination of ambient flow logging, with pumping and/or injecting induced flow logging. This application showed that the flowmeter logging detected hydraulic passes conveniently and accurately compared with other hydraulic tests. Hydraulic conductivity by using flowmeter logging was assessed above 10 -6 m/sec and within one order from comparison with injection packer tests. We suggest that appropriate application of the flowmeter logging for the siting is conducted before hydraulic tests because test sections and monitoring sections are decided rationally for procurement of quantitative hydraulic data. (author)

  2. Development and engineering application of rotating drum acid-curing equipment in uranium mills

    International Nuclear Information System (INIS)

    Liu Wenhua

    2006-01-01

    The development and engineering application of rotating drum acid-curing equipment for 'strong acid-curing and ferri-trickle leaching' process are introduced, including the design of main structure, problems appeared in the development and engineering application, and methods solved. (authors)

  3. Photonics applications and web engineering: WILGA Winter 2016

    Science.gov (United States)

    Romaniuk, Ryszard S.

    2016-09-01

    Since twenty years, young researchers form the Institute of Electronic Systems, Warsaw University of Technology, organize two times a year, under only a marginal supervision of the senior faculty members, under the patronage of WEiTI PW, KEiT PAN, SPIE, IEEE, PKOpto SEP and PSF, the WILGA Symposium on advanced, integrated functional electronic, photonic and mechatronic systems [1-5]. All aspects are considered like: research and development, theory and design, technology - material and construction, software and hardware, commissioning and tests, as well as pilot and practical applications. The applications concern mostly, which turned after several years to be a proud specialization of the WILGA Symposium, Internet engineering, high energy physics experiments, new power industry including fusion, nuclear industry, space and satellite technologies, telecommunications, smart municipal environment, as well as biology and medicine [6-8]. XXXVIIth WILGA Symposium was held on 29-31 January 2016 and gathered a few tens of young researchers active in the mentioned research areas. There were presented a few tens of technical papers which will be published in Proc.SPIE together with the accepted articles from the Summer Edition of the WILGA Symposium scheduled for 29.05-06.06.2016. This article is a digest of chosen presentations from WILGA Symposium 2016 Winter Edition. The survey is narrowed to a few chosen and main topical tracks, like electronics and photonics design using industrial standards like ATCA/MTCA, also particular designs of functional systems using this series of industrial standards. The paper, summarizing traditionally since many years the accomplished WILGA Symposium organized by young researchers from Warsaw University of Technology, is also the following part of a cycle of papers concerning their participation in design of new generations of electronic systems used in discovery experiments in Poland and in leading research laboratories of the world.

  4. Polycaprolactone Scaffolds Fabricated via Bioextrusion for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Marco Domingos

    2009-01-01

    Full Text Available The most promising approach in Tissue Engineering involves the seeding of porous, biocompatible/biodegradable scaffolds, with donor cells to promote tissue regeneration. Additive biomanufacturing processes are increasingly recognized as ideal techniques to produce 3D structures with optimal pore size and spatial distribution, providing an adequate mechanical support for tissue regeneration while shaping in-growing tissues. This paper presents a novel extrusion-based system to produce 3D scaffolds with controlled internal/external geometry for TE applications.The BioExtruder is a low-cost system that uses a proper fabrication code based on the ISO programming language enabling the fabrication of multimaterial scaffolds. Poly(ε-caprolactone was the material chosen to produce porous scaffolds, made by layers of directionally aligned microfilaments. Chemical, morphological, and in vitro biological evaluation performed on the polymeric constructs revealed a high potential of the BioExtruder to produce 3D scaffolds with regular and reproducible macropore architecture, without inducing relevant chemical and biocompatibility alterations of the material.

  5. Cobalt doped proangiogenic hydroxyapatite for bone tissue engineering application

    International Nuclear Information System (INIS)

    Kulanthaivel, Senthilguru; Roy, Bibhas; Agarwal, Tarun; Giri, Supratim; Pramanik, Krishna; Pal, Kunal; Ray, Sirsendu S.; Maiti, Tapas K.; Banerjee, Indranil

    2016-01-01

    ABSTRACT: The present study delineates the synthesis and characterization of cobalt doped proangiogenic–osteogenic hydroxyapatite. Hydroxyapatite samples, doped with varying concentrations of bivalent cobalt (Co"2"+) were prepared by the ammoniacal precipitation method and the extent of doping was measured by ICP–OES. The crystalline structure of the doped hydroxyapatite samples was confirmed by XRD and FTIR studies. Analysis pertaining to the effect of doped hydroxyapatite on cell cycle progression and proliferation of MG-63 cells revealed that the doping of cobalt supported the cell viability and proliferation up to a threshold limit. Furthermore, such level of doping also induced differentiation of the bone cells, which was evident from the higher expression of differentiation markers (Runx2 and Osterix) and better nodule formation (SEM study). Western blot analysis in conjugation with ELISA study confirmed that the doped HAp samples significantly increased the expression of HIF-1α and VEGF in MG-63 cells. The analysis described here confirms the proangiogenic–osteogenic properties of the cobalt doped hydroxyapatite and indicates its potential application in bone tissue engineering. - Highlights: • Cobalt (Co"+"2) doped hydroxyapatite (Co-HAp) can be prepared by the wet chemical method. • The concentration of Co"+"2 influences the physico-chemical properties of HAp. • Co-HAp was found to be biocompatible and osteogenic. • Co-HAp enhanced cellular VEGF secretion through HIF-1α stabilization. • The optimum biological performance of Co-HAp was achieved for 0.33% (w/w) Co"+"2 doping.

  6. Cobalt doped proangiogenic hydroxyapatite for bone tissue engineering application.

    Science.gov (United States)

    Kulanthaivel, Senthilguru; Roy, Bibhas; Agarwal, Tarun; Giri, Supratim; Pramanik, Krishna; Pal, Kunal; Ray, Sirsendu S; Maiti, Tapas K; Banerjee, Indranil

    2016-01-01

    The present study delineates the synthesis and characterization of cobalt doped proangiogenic-osteogenic hydroxyapatite. Hydroxyapatite samples, doped with varying concentrations of bivalent cobalt (Co(2+)) were prepared by the ammoniacal precipitation method and the extent of doping was measured by ICP-OES. The crystalline structure of the doped hydroxyapatite samples was confirmed by XRD and FTIR studies. Analysis pertaining to the effect of doped hydroxyapatite on cell cycle progression and proliferation of MG-63 cells revealed that the doping of cobalt supported the cell viability and proliferation up to a threshold limit. Furthermore, such level of doping also induced differentiation of the bone cells, which was evident from the higher expression of differentiation markers (Runx2 and Osterix) and better nodule formation (SEM study). Western blot analysis in conjugation with ELISA study confirmed that the doped HAp samples significantly increased the expression of HIF-1α and VEGF in MG-63 cells. The analysis described here confirms the proangiogenic-osteogenic properties of the cobalt doped hydroxyapatite and indicates its potential application in bone tissue engineering. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Probability with applications in engineering, science, and technology

    CERN Document Server

    Carlton, Matthew A

    2017-01-01

    This updated and revised first-course textbook in applied probability provides a contemporary and lively post-calculus introduction to the subject of probability. The exposition reflects a desirable balance between fundamental theory and many applications involving a broad range of real problem scenarios. It is intended to appeal to a wide audience, including mathematics and statistics majors, prospective engineers and scientists, and those business and social science majors interested in the quantitative aspects of their disciplines. The textbook contains enough material for a year-long course, though many instructors will use it for a single term (one semester or one quarter). As such, three course syllabi with expanded course outlines are now available for download on the book’s page on the Springer website. A one-term course would cover material in the core chapters (1-4), supplemented by selections from one or more of the remaining chapters on statistical inference (Ch. 5), Markov chains (Ch. 6), stoch...

  8. High damping Fe-Mn martensitic alloys for engineering applications

    International Nuclear Information System (INIS)

    Baik, S.-H.

    2000-01-01

    Conventional methods for reducing vibration in engineering designs (i.e. by stiffening or detuning) may be undesirable or inadequate in conditions where size or weight must be minimized or where complex vibration spectra exist. Alloys which combine high damping capacity with good mechanical properties can provide attractive technical and economic solutions to problems involving seismic, shock and vibration isolation. To meet these trends, we have developed a new high damping Fe-17%Mn alloy. Also, the alloy has advantages of good mechanical properties and is more economical than any other known damping alloys (a quarter the cost of non-ferrous damping alloy). Thus, the high damping Fe-17%Mn alloy can be widely applied to household appliances, automobiles, industrial facilities and power plant components with its excellent damping capacity (SDC, 30%) and mechanical property (T.S. 700 MPa). It is the purpose of this paper to introduce the characterization of the high damping Fe-17%Mn alloy and the results of retrofit of several such applications. (orig.)

  9. Engineering of Semiconductor Nanocrystals for Light Emitting Applications

    Directory of Open Access Journals (Sweden)

    Francesco Todescato

    2016-08-01

    Full Text Available Semiconductor nanocrystals are rapidly spreading into the display and lighting markets. Compared with liquid crystal and organic LED displays, nanocrystalline quantum dots (QDs provide highly saturated colors, wide color gamut, resolution, rapid response time, optical efficiency, durability and low cost. This remarkable progress has been made possible by the rapid advances in the synthesis of colloidal QDs and by the progress in understanding the intriguing new physics exhibited by these nanoparticles. In this review, we provide support to the idea that suitably engineered core/graded-shell QDs exhibit exceptionally favorable optical properties, photoluminescence and optical gain, while keeping the synthesis facile and producing QDs well suited for light emitting applications. Solid-state laser emitters can greatly profit from QDs as efficient gain materials. Progress towards fabricating low threshold, solution processed DFB lasers that are optically pumped using one- and two-photon absorption is reviewed. In the field of display technologies, the exploitation of the exceptional photoluminescence properties of QDs for LCD backlighting has already advanced to commercial levels. The next big challenge is to develop the electroluminescence properties of QD to a similar state. We present an overview of QLED devices and of the great perspectives for next generation display and lighting technologies.

  10. Research on application of knowledge engineering to nuclear power stations

    International Nuclear Information System (INIS)

    Umeda, Takeo; Kiyohashi, Satoshi

    1990-01-01

    Recently, the research on the software and hardware regarding knowledge engineering has been advanced eagerly. Especially the applicability of expert systems is high. When expert systems are introduced into nuclear power stations, it is necessary to make the plan for introduction based on the detailed knowledge on the works in nuclear power stations, and to improve the system repeatedly by adopting the opinion and request of those in charge upon the trial use. Tohoku Electric Power Co. was able to develop the expert system of practically usable scale 'Supporting system for deciding fuel movement procedure'. The survey and analysis of the works in nuclear power stations, the selection of the system to be developed and so on are reported. In No. 1 plant of Onagawa Nuclear Power Station of BWR type, up to 1/3 of the fuel is replaced at the time of the regular inspection. Some fuel must be taken to outside for ensuring the working space. The works of deciding fuel movement procedure, the development of the system and its evaluation are described. (K.I.)

  11. Band gap engineering of BC2N for nanoelectronic applications

    Science.gov (United States)

    Lim, Wei Hong; Hamzah, Afiq; Ahmadi, Mohammad Taghi; Ismail, Razali

    2017-12-01

    The BC2N as an example of boron-carbon-nitride (BCN), has the analogous structure as the graphene and boron nitride. It is predicted to have controllable electronic properties. Therefore, the analytical study on the engineer-able band gap of the BC2N is carried out based on the schematic structure of BC2N. The Nearest Neighbour Tight Binding (NNTB) model is employed with the dispersion relation and the density of state (DOS) as the main band gap analysing parameter. The results show that the hopping integrals having the significant effect on the band gap, band structure and DOS of BC2N nanowire (BC2NNW) need to be taken into consideration. The presented model indicates consistent trends with the published computational results around the Dirac points with the extracted band gap of 0.12 eV. Also, it is distinguished that wide energy gap of boron nitride (BN) is successfully narrowed by this carbon doped material which assures the application of BC2N on the nanoelectronics and optoelectronics in the near future.

  12. Solid state nuclear track detection principles, methods and applications

    CERN Document Server

    Durrani, S A; ter Haar, D

    1987-01-01

    Solid State Nuclear Track Detection: Principles, Methods and Applications is the second book written by the authors after Nuclear Tracks in Solids: Principles and Applications. The book is meant as an introduction to the subject solid state of nuclear track detection. The text covers the interactions of charged particles with matter; the nature of the charged-particle track; the methodology and geometry of track etching; thermal fading of latent damage trails on tracks; the use of dielectric track recorders in particle identification; radiation dossimetry; and solid state nuclear track detecti

  13. CO2 laser-driven Stirling engine. [space power applications

    Science.gov (United States)

    Lee, G.; Perry, R. L.; Carney, B.

    1978-01-01

    A 100-W Beale free-piston Stirling engine was powered remotely by a CO2 laser for long periods of time. The engine ran on both continuous-wave and pulse laser input. The working fluid was helium doped with small quantities of sulfur hexafluoride, SF6. The CO2 radiation was absorbed by the vibrational modes of the sulfur hexafluoride, which in turn transferred the energy to the helium to drive the engine. Electrical energy was obtained from a linear alternator attached to the piston of the engine. Engine pressures, volumes, and temperatures were measured to determine engine performance. It was found that the pulse radiation mode was more efficient than the continuous-wave mode. An analysis of the engine heat consumption indicated that heat losses around the cylinder and the window used to transmit the beam into the engine accounted for nearly half the energy input. The overall efficiency, that is, electrical output to laser input, was approximately 0.75%. However, this experiment was not designed for high efficiency but only to demonstrate the concept of a laser-driven engine. Based on this experiment, the engine could be modified to achieve efficiencies of perhaps 25-30%.

  14. GPR applications in Civil Engineering in Spain - state-of-the-art

    Science.gov (United States)

    Pérez Gracia, Vega; Solla, Mercedes; Santos-Assunçao, Sonia; Lorenzo, Henrique

    2014-05-01

    GPR was introduced in Spain in 1990, and the first significant work was the PhD thesis of H. Lorenzo in 1994. Due to its versatile applicability, the employ has been increased and actually, GPR is extensively used in detection of pipes, wiring and urban services mainly. During the last years, this method was also widely utilized in the detection of graves from the civil war and in forensic studies, with irregular results. It was also commonly applied in archaeology. Actually exists more than 20 private companies offering geotechnical services by means of GPR. Also, several public institutions as Universities and Research Institutes base part of their research in GPR or in GPR applications. Notwithstanding, no training courses of specific formation on GPR is offered, but in several doctorate programs it is possible to work with GPR. Also, in many schools, GPR is part of the geophysical formation of graduate students. However, no national guidelines and rules exist, and each company defines the investigation protocols. Nevertheless, one of the aims of the Comisión Española de Geodesia y Geofísica (Spanish Committee for Geodesy and Geophysics) is to define guidelines for the GPR studies. Probably, the existence of national guidelines or perhaps European guidelines could be the most effective way to promote the responsible use of GPR in different domains. On the other hand, perhaps recommendations on the use of combined methodologies could be a practical way to persuade in the application of geophysical non-destructive technologies. The CEDEX, Centro de Estudios y Experimentación de Obras Públicas (Center for Studies and Experimentation in Civil Engineering), which is a civil engineering research agency in Spain, offers different test sites to calibrate and evaluate the method. It is an autonomous organization, organically ascribed at present to the Ministry of Fomento, and functionally ascribed to the Ministries of Fomento and Medioambiente of Spain, giving

  15. Conductometric Sensor for Soot Mass Flow Detection in Exhausts of Internal Combustion Engines

    Science.gov (United States)

    Feulner, Markus; Hagen, Gunter; Müller, Andreas; Schott, Andreas; Zöllner, Christian; Brüggemann, Dieter; Moos, Ralf

    2015-01-01

    Soot sensors are required for on-board diagnostics (OBD) of automotive diesel particulate filters (DPF) to detect filter failures. Widely used for this purpose are conductometric sensors, measuring an electrical current or resistance between two electrodes. Soot particles deposit on the electrodes, which leads to an increase in current or decrease in resistance. If installed upstream of a DPF, the “engine-out” soot emissions can also be determined directly by soot sensors. Sensors were characterized in diesel engine real exhausts under varying operation conditions and with two different kinds of diesel fuel. The sensor signal was correlated to the actual soot mass and particle number, measured with an SMPS. Sensor data and soot analytics (SMPS) agreed very well, an impressing linear correlation in a double logarithmic representation was found. This behavior was even independent of the used engine settings or of the biodiesel content. PMID:26580621

  16. Conductometric Sensor for Soot Mass Flow Detection in Exhausts of Internal Combustion Engines.

    Science.gov (United States)

    Feulner, Markus; Hagen, Gunter; Müller, Andreas; Schott, Andreas; Zöllner, Christian; Brüggemann, Dieter; Moos, Ralf

    2015-11-13

    Soot sensors are required for on-board diagnostics (OBD) of automotive diesel particulate filters (DPF) to detect filter failures. Widely used for this purpose are conductometric sensors, measuring an electrical current or resistance between two electrodes. Soot particles deposit on the electrodes, which leads to an increase in current or decrease in resistance. If installed upstream of a DPF, the "engine-out" soot emissions can also be determined directly by soot sensors. Sensors were characterized in diesel engine real exhausts under varying operation conditions and with two different kinds of diesel fuel. The sensor signal was correlated to the actual soot mass and particle number, measured with an SMPS. Sensor data and soot analytics (SMPS) agreed very well, an impressing linear correlation in a double logarithmic representation was found. This behavior was even independent of the used engine settings or of the biodiesel content.

  17. Conductometric Sensor for Soot Mass Flow Detection in Exhausts of Internal Combustion Engines

    Directory of Open Access Journals (Sweden)

    Markus Feulner

    2015-11-01

    Full Text Available Soot sensors are required for on-board diagnostics (OBD of automotive diesel particulate filters (DPF to detect filter failures. Widely used for this purpose are conductometric sensors, measuring an electrical current or resistance between two electrodes. Soot particles deposit on the electrodes, which leads to an increase in current or decrease in resistance. If installed upstream of a DPF, the “engine-out” soot emissions can also be determined directly by soot sensors. Sensors were characterized in diesel engine real exhausts under varying operation conditions and with two different kinds of diesel fuel. The sensor signal was correlated to the actual soot mass and particle number, measured with an SMPS. Sensor data and soot analytics (SMPS agreed very well, an impressing linear correlation in a double logarithmic representation was found. This behavior was even independent of the used engine settings or of the biodiesel content.

  18. Optical detection of random features for high security applications

    Science.gov (United States)

    Haist, T.; Tiziani, H. J.

    1998-02-01

    Optical detection of random features in combination with digital signatures based on public key codes in order to recognize counterfeit objects will be discussed. Without applying expensive production techniques objects are protected against counterfeiting. Verification is done off-line by optical means without a central authority. The method is applied for protecting banknotes. Experimental results for this application are presented. The method is also applicable for identity verification of a credit- or chip-card holder.

  19. Particular bi-fuel application of spark ignition engines

    Science.gov (United States)

    Raţiu, S.; Alexa, V.; Kiss, I.

    2016-02-01

    This paper presents a comparative test concerning the operation of a spark-ignition engine, make: Dacia 1300, model: 810.99, fuelled alternatively with gasoline and LPG (Liquefied Petroleum Gas). The tests carried out show, on the one hand, the maintenance of power and torque performances in both engine fuelling cases, for all the engine operation regimes, and, on the other hand, a considerable decrease in CO and HC emissions when using poor mixtures related to LPG fuelling.

  20. Application of radioactivity to subterranean hydraulic engineering (1961)

    International Nuclear Information System (INIS)

    Hours, R.

    1961-01-01

    The search for radioactive tracers for water capable of percolating through permeable grounds without significant absorption has led to the choosing of two isotopes, bromine 82 (half-life 36 hours) and iodine (half-life 8 days), both γ emitters; various combinations of other γ emitters with longer half-lives have been tried but with only partial success. The recent progress in the dosage of tritium should make it possible to widen the field of application of this tracer which is unique in its kind. Being detectable at concentrations of 10 -6 to 10 -8 curies per cubic meter, the radioactive tracers are suitable for all the usual applications of conventional tracers; furthermore, some original techniques have been devised for measurements of flow, of reservoir capacity, of porosity and of permeability. Techniques based on the absorption and scattering of γ-rays have also been developed for the measurement of the density, the humidity and the porosity of soils, and also for their analysis. Up to the present, radioactivity has been mainly applied to the study of oil-bearing formations. Furthermore, the study of the distribution of natural of thermonuclear tritium has contributed greatly to the study of the hydrological cycle. (author) [fr

  1. Computational studies of an intake manifold for restricted engine application

    Science.gov (United States)

    Prasetyo, Bagus Dwi; Ubaidillah, Maharani, Elliza Tri; Setyohandoko, Gabriel; Idris, Muhammad Idzdihar

    2018-02-01

    The Formula Society of Automotive Engineer (FSAE) student competition is an international contest for a vehicle that entirely designed and built by students from various universities. The engine design in the Formula SAE competition has to comply a tight regulation. Concerning the engine intake line, an air restrictor of circular cross-section less than 20 mm must be fitted between the throttle valve and the engine inlet. The throat is aimed to limit the engine air flow rate as it strongly influences the volumetric efficiency and then the maximum power. This article focuses on the design of the engine intake system of the Bengawan FSAE team vehicle to optimize the engine power output and its stability. The performance of engine intake system is studied through computational fluid dynamics (CFD). The objective of CFD is to know the pressure, velocity, and airflow of the air intake manifold for the best performance of the engine. The three-dimensional drawing of the intake manifold was made, and CFD simulation was conducted using ANSYS FLUENT. Two models were studied. The result shows that the different design produces a different value of the velocity of airflow and the kind of flow type.

  2. Applications of human factors engineering in the digital HMI

    International Nuclear Information System (INIS)

    Zhou Bingjian

    2014-01-01

    In order to prevent and minimize human errors in the digital main control room, the principles of human factors engineering must be complied strictly in the design process of digital human-machine interface. This paper briefly describes the basic human factors engineering principles of designing main control room, introduces the main steps to implement the human factors engineering verification and validation of main control room, including HSI task support verification, human factors engineering design verification and integrated system validation. Meanwhile, according to the new digital human-machine interface characteristics, the development models of human error are analyzed. (author)

  3. A Naive-Bayes classifier for damage detection in engineering materials

    Energy Technology Data Exchange (ETDEWEB)

    Addin, O. [Laboratory of Intelligent Systems, Institute of Advanced Technology, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Sapuan, S.M. [Department of Mechanical and Manufacturing Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia)]. E-mail: sapuan@eng.upm.edu.my; Mahdi, E. [Department of Aerospace Engineering, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia); Othman, M. [Department of Communication Technology and Networks, Universiti Putra Malaysia, 43400 Serdang, Selangor (Malaysia)

    2007-07-01

    This paper is intended to introduce the Bayesian network in general and the Naive-Bayes classifier in particular as one of the most successful classification systems to simulate damage detection in engineering materials. A method for feature subset selection has also been introduced too. The method is based on mean and maximum values of the amplitudes of waves after dividing them into folds then grouping them by a clustering algorithm (e.g. k-means algorithm). The Naive-Bayes classifier and the feature sub-set selection method were analyzed and tested on two sets of data. The data sets were conducted based on artificial damages created in quasi isotopic laminated composites of the AS4/3501-6 graphite/epoxy system and ball bearing of the type 6204 with a steel cage. The Naive-Bayes classifier and the proposed feature subset selection algorithm have been shown as efficient techniques for damage detection in engineering materials.

  4. Reverse Engineering and Security Evaluation of Commercial Tags for RFID-Based IoT Applications.

    Science.gov (United States)

    Fernández-Caramés, Tiago M; Fraga-Lamas, Paula; Suárez-Albela, Manuel; Castedo, Luis

    2016-12-24

    The Internet of Things (IoT) is a distributed system of physical objects that requires the seamless integration of hardware (e.g., sensors, actuators, electronics) and network communications in order to collect and exchange data. IoT smart objects need to be somehow identified to determine the origin of the data and to automatically detect the elements around us. One of the best positioned technologies to perform identification is RFID (Radio Frequency Identification), which in the last years has gained a lot of popularity in applications like access control, payment cards or logistics. Despite its popularity, RFID security has not been properly handled in numerous applications. To foster security in such applications, this article includes three main contributions. First, in order to establish the basics, a detailed review of the most common flaws found in RFID-based IoT systems is provided, including the latest attacks described in the literature. Second, a novel methodology that eases the detection and mitigation of such flaws is presented. Third, the latest RFID security tools are analyzed and the methodology proposed is applied through one of them (Proxmark 3) to validate it. Thus, the methodology is tested in different scenarios where tags are commonly used for identification. In such systems it was possible to clone transponders, extract information, and even emulate both tags and readers. Therefore, it is shown that the methodology proposed is useful for auditing security and reverse engineering RFID communications in IoT applications. It must be noted that, although this paper is aimed at fostering RFID communications security in IoT applications, the methodology can be applied to any RFID communications protocol.

  5. Reverse Engineering and Security Evaluation of Commercial Tags for RFID-Based IoT Applications

    Directory of Open Access Journals (Sweden)

    Tiago M. Fernández-Caramés

    2016-12-01

    Full Text Available The Internet of Things (IoT is a distributed system of physical objects that requires the seamless integration of hardware (e.g., sensors, actuators, electronics and network communications in order to collect and exchange data. IoT smart objects need to be somehow identified to determine the origin of the data and to automatically detect the elements around us. One of the best positioned technologies to perform identification is RFID (Radio Frequency Identification, which in the last years has gained a lot of popularity in applications like access control, payment cards or logistics. Despite its popularity, RFID security has not been properly handled in numerous applications. To foster security in such applications, this article includes three main contributions. First, in order to establish the basics, a detailed review of the most common flaws found in RFID-based IoT systems is provided, including the latest attacks described in the literature. Second, a novel methodology that eases the detection and mitigation of such flaws is presented. Third, the latest RFID security tools are analyzed and the methodology proposed is applied through one of them (Proxmark 3 to validate it. Thus, the methodology is tested in different scenarios where tags are commonly used for identification. In such systems it was possible to clone transponders, extract information, and even emulate both tags and readers. Therefore, it is shown that the methodology proposed is useful for auditing security and reverse engineering RFID communications in IoT applications. It must be noted that, although this paper is aimed at fostering RFID communications security in IoT applications, the methodology can be applied to any RFID communications protocol.

  6. Reverse Engineering and Security Evaluation of Commercial Tags for RFID-Based IoT Applications

    Science.gov (United States)

    Fernández-Caramés, Tiago M.; Fraga-Lamas, Paula; Suárez-Albela, Manuel; Castedo, Luis

    2016-01-01

    The Internet of Things (IoT) is a distributed system of physical objects that requires the seamless integration of hardware (e.g., sensors, actuators, electronics) and network communications in order to collect and exchange data. IoT smart objects need to be somehow identified to determine the origin of the data and to automatically detect the elements around us. One of the best positioned technologies to perform identification is RFID (Radio Frequency Identification), which in the last years has gained a lot of popularity in applications like access control, payment cards or logistics. Despite its popularity, RFID security has not been properly handled in numerous applications. To foster security in such applications, this article includes three main contributions. First, in order to establish the basics, a detailed review of the most common flaws found in RFID-based IoT systems is provided, including the latest attacks described in the literature. Second, a novel methodology that eases the detection and mitigation of such flaws is presented. Third, the latest RFID security tools are analyzed and the methodology proposed is applied through one of them (Proxmark 3) to validate it. Thus, the methodology is tested in different scenarios where tags are commonly used for identification. In such systems it was possible to clone transponders, extract information, and even emulate both tags and readers. Therefore, it is shown that the methodology proposed is useful for auditing security and reverse engineering RFID communications in IoT applications. It must be noted that, although this paper is aimed at fostering RFID communications security in IoT applications, the methodology can be applied to any RFID communications protocol. PMID:28029119

  7. Probabilistic pipe fracture evaluations for leak-rate-detection applications

    International Nuclear Information System (INIS)

    Rahman, S.; Ghadiali, N.; Paul, D.; Wilkowski, G.

    1995-04-01

    Regulatory Guide 1.45, open-quotes Reactor Coolant Pressure Boundary Leakage Detection Systems,close quotes was published by the U.S. Nuclear Regulatory Commission (NRC) in May 1973, and provides guidance on leak detection methods and system requirements for Light Water Reactors. Additionally, leak detection limits are specified in plant Technical Specifications and are different for Boiling Water Reactors (BWRs) and Pressurized Water Reactors (PWRs). These leak detection limits are also used in leak-before-break evaluations performed in accordance with Draft Standard Review Plan, Section 3.6.3, open-quotes Leak Before Break Evaluation Proceduresclose quotes where a margin of 10 on the leak detection limit is used in determining the crack size considered in subsequent fracture analyses. This study was requested by the NRC to: (1) evaluate the conditional failure probability for BWR and PWR piping for pipes that were leaking at the allowable leak detection limit, and (2) evaluate the margin of 10 to determine if it was unnecessarily large. A probabilistic approach was undertaken to conduct fracture evaluations of circumferentially cracked pipes for leak-rate-detection applications. Sixteen nuclear piping systems in BWR and PWR plants were analyzed to evaluate conditional failure probability and effects of crack-morphology variability on the current margins used in leak rate detection for leak-before-break

  8. Application of Dimethyl Ether in Compression Ignition Engines

    DEFF Research Database (Denmark)

    Hansen, Kim Rene

    -Marathon. The diesel engine test results from 1995 showed that DME is a superb diesel fuel. DME is easy to ignite by compression ignition and it has a molecular structure that results in near-zero emission of particulates when burned. These are features of a fuel that are highly desirable in a diesel engine....... The challenges with DME as a diesel engine fuel are mainly related to poor lubricity and incompatibility with a range of elastomers commonly used for seals in fuel injection systems. This means that although DME burns well in a diesel engine designing a fuel injection system for DME is challenging. Since...... then studies have revealed that the injection pressure for DME does not have to be as high as with diesel to achieve satisfactory performance. This opens for a larger range of possibilities when designing injection systems. In the period from 2004 to 2009 the DME engine was perfected for use in the car DTU...

  9. SQUID sensor application for small metallic particle detection

    International Nuclear Information System (INIS)

    Tanaka, Saburo; Hatsukade, Yoshimi; Ohtani, Takeyoshi; Suzuki, Shuichi

    2009-01-01

    High-Tc superconducting quantum interference device (SQUID) is an ultra-sensitive magnetic sensor. Since the performance of the SQUID is improved and stabilized, now it is ready for application. One strong candidate for application is a detection system of magnetic foreign matters in industrial products or beverages. There is a possibility that ultra-small metallic foreign matter has been accidentally mixed with industrial products such as lithium ion batteries. If this happens, the manufacturer of the product suffers a great loss recalling products. The outer dimension of metallic particles less than 100 μm cannot be detected by an X-ray imaging, which is commonly used for the inspection. Ionization of the material is also a big issue for beverages in the case of the X-ray imaging. Therefore a highly sensitive and safety detection system for small foreign matters is required. We developed detection systems based on high-Tc SQUID with a high-performance magnetic shield. We could successfully measure small iron particles of 100 μm on a belt conveyer and stainless steel balls of 300 μm in water. These detection levels were hard to be achieved by a conventional X-ray detection or other methods

  10. Detecting content adaptive scaling of images for forensic applications

    Science.gov (United States)

    Fillion, Claude; Sharma, Gaurav

    2010-01-01

    Content-aware resizing methods have recently been developed, among which, seam-carving has achieved the most widespread use. Seam-carving's versatility enables deliberate object removal and benign image resizing, in which perceptually important content is preserved. Both types of modifications compromise the utility and validity of the modified images as evidence in legal and journalistic applications. It is therefore desirable that image forensic techniques detect the presence of seam-carving. In this paper we address detection of seam-carving for forensic purposes. As in other forensic applications, we pose the problem of seam-carving detection as the problem of classifying a test image in either of two classes: a) seam-carved or b) non-seam-carved. We adopt a pattern recognition approach in which a set of features is extracted from the test image and then a Support Vector Machine based classifier, trained over a set of images, is utilized to estimate which of the two classes the test image lies in. Based on our study of the seam-carving algorithm, we propose a set of intuitively motivated features for the detection of seam-carving. Our methodology for detection of seam-carving is then evaluated over a test database of images. We demonstrate that the proposed method provides the capability for detecting seam-carving with high accuracy. For images which have been reduced 30% by benign seam-carving, our method provides a classification accuracy of 91%.

  11. Methylcellulose Based Thermally Reversible Hydrogel System for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Ram V. Devireddy

    2013-06-01

    Full Text Available The thermoresponsive behavior of a Methylcellulose (MC polymer was systematically investigated to determine its usability in constructing MC based hydrogel systems in cell sheet engineering applications. Solution-gel analyses were made to study the effects of polymer concentration, molecular weight and dissolved salts on the gelation of three commercially available MCs using differential scanning calorimeter and rheology. For investigation of the hydrogel stability and fluid uptake capacity, swelling and degradation experiments were performed with the hydrogel system exposed to cell culture solutions at incubation temperature for several days. From these experiments, the optimal composition of MC-water-salt that was able to produce stable hydrogels at or above 32 °C, was found to be 12% to 16% of MC (Mol. wt. of 15,000 in water with 0.5× PBS (~150mOsm. This stable hydrogel system was then evaluated for a week for its efficacy to support the adhesion and growth of specific cells in culture; in our case the stromal/stem cells derived from human adipose tissue derived stem cells (ASCs. The results indicated that the addition (evenly spread of ~200 µL of 2 mg/mL bovine collagen type -I (pH adjusted to 7.5 over the MC hydrogel surface at 37 °C is required to improve the ASC adhesion and proliferation. Upon confluence, a continuous monolayer ASC sheet was formed on the surface of the hydrogel system and an intact cell sheet with preserved cell–cell and cell–extracellular matrix was spontaneously and gradually detached when the grown cell sheet was removed from the incubator and exposed to room temperature (~30 °C within minutes.

  12. Methylcellulose based thermally reversible hydrogel system for tissue engineering applications.

    Science.gov (United States)

    Thirumala, Sreedhar; Gimble, Jeffrey M; Devireddy, Ram V

    2013-06-25

    The thermoresponsive behavior of a Methylcellulose (MC) polymer was systematically investigated to determine its usability in constructing MC based hydrogel systems in cell sheet engineering applications. Solution-gel analyses were made to study the effects of polymer concentration, molecular weight and dissolved salts on the gelation of three commercially available MCs using differential scanning calorimeter and rheology. For investigation of the hydrogel stability and fluid uptake capacity, swelling and degradation experiments were performed with the hydrogel system exposed to cell culture solutions at incubation temperature for several days. From these experiments, the optimal composition of MC-water-salt that was able to produce stable hydrogels at or above 32 °C, was found to be 12% to 16% of MC (Mol. wt. of 15,000) in water with 0.5× PBS (~150mOsm). This stable hydrogel system was then evaluated for a week for its efficacy to support the adhesion and growth of specific cells in culture; in our case the stromal/stem cells derived from human adipose tissue derived stem cells (ASCs). The results indicated that the addition (evenly spread) of ~200 µL of 2 mg/mL bovine collagen type -I (pH adjusted to 7.5) over the MC hydrogel surface at 37 °C is required to improve the ASC adhesion and proliferation. Upon confluence, a continuous monolayer ASC sheet was formed on the surface of the hydrogel system and an intact cell sheet with preserved cell-cell and cell-extracellular matrix was spontaneously and gradually detached when the grown cell sheet was removed from the incubator and exposed to room temperature (~30 °C) within minutes.

  13. Potential applications of skip SMV with thrust engine

    Science.gov (United States)

    Wang, Weilin; Savvaris, Al

    2016-11-01

    This paper investigates the potential applications of Space Maneuver Vehicles (SMV) with skip trajectory. Due to soaring space operations over the past decades, the risk of space debris has considerably increased such as collision risks with space asset, human property on ground and even aviation. Many active debris removal methods have been investigated and in this paper, a debris remediation method is first proposed based on skip SMV. The key point is to perform controlled re-entry. These vehicles are expected to achieve a trans-atmospheric maneuver with thrust engine. If debris is released at altitude below 80 km, debris could be captured by the atmosphere drag force and re-entry interface prediction accuracy is improved. Moreover if the debris is released in a cargo at a much lower altitude, this technique protects high value space asset from break up by the atmosphere and improves landing accuracy. To demonstrate the feasibility of this concept, the present paper presents the simulation results for two specific mission profiles: (1) descent to predetermined altitude; (2) descent to predetermined point (altitude, longitude and latitude). The evolutionary collocation method is adopted for skip trajectory optimization due to its global optimality and high-accuracy. This method is actually a two-step optimization approach based on the heuristic algorithm and the collocation method. The optimal-control problem is transformed into a nonlinear programming problem (NLP) which can be efficiently and accurately solved by the sequential quadratic programming (SQP) procedure. However, such a method is sensitive to initial values. To reduce the sensitivity problem, genetic algorithm (GA) is adopted to refine the grids and provide near optimum initial values. By comparing the simulation data from different scenarios, it is found that skip SMV is feasible in active debris removal and the evolutionary collocation method gives a truthful re-entry trajectory that satisfies the

  14. Cobalt doped proangiogenic hydroxyapatite for bone tissue engineering application

    Energy Technology Data Exchange (ETDEWEB)

    Kulanthaivel, Senthilguru [Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha 769008 (India); Roy, Bibhas [Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302 (India); Agarwal, Tarun [Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha 769008 (India); Giri, Supratim [Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008 (India); Pramanik, Krishna; Pal, Kunal; Ray, Sirsendu S. [Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha 769008 (India); Maiti, Tapas K. [Department of Biotechnology, Indian Institute of Technology Kharagpur, Kharagpur, West Bengal 721302 (India); Banerjee, Indranil, E-mail: indraniliit@gmail.com [Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha 769008 (India)

    2016-01-01

    ABSTRACT: The present study delineates the synthesis and characterization of cobalt doped proangiogenic–osteogenic hydroxyapatite. Hydroxyapatite samples, doped with varying concentrations of bivalent cobalt (Co{sup 2+}) were prepared by the ammoniacal precipitation method and the extent of doping was measured by ICP–OES. The crystalline structure of the doped hydroxyapatite samples was confirmed by XRD and FTIR studies. Analysis pertaining to the effect of doped hydroxyapatite on cell cycle progression and proliferation of MG-63 cells revealed that the doping of cobalt supported the cell viability and proliferation up to a threshold limit. Furthermore, such level of doping also induced differentiation of the bone cells, which was evident from the higher expression of differentiation markers (Runx2 and Osterix) and better nodule formation (SEM study). Western blot analysis in conjugation with ELISA study confirmed that the doped HAp samples significantly increased the expression of HIF-1α and VEGF in MG-63 cells. The analysis described here confirms the proangiogenic–osteogenic properties of the cobalt doped hydroxyapatite and indicates its potential application in bone tissue engineering. - Highlights: • Cobalt (Co{sup +2}) doped hydroxyapatite (Co-HAp) can be prepared by the wet chemical method. • The concentration of Co{sup +2} influences the physico-chemical properties of HAp. • Co-HAp was found to be biocompatible and osteogenic. • Co-HAp enhanced cellular VEGF secretion through HIF-1α stabilization. • The optimum biological performance of Co-HAp was achieved for 0.33% (w/w) Co{sup +2} doping.

  15. Electronic aroma detection technology for forensic and law enforcement applications

    Energy Technology Data Exchange (ETDEWEB)

    Barshick, S.-A.; Griest, W.H.; Vass, A.A.

    1996-12-31

    A major problem hindering criminal investigations is the lack of appropriate tools for proper crime scene investigations. Often locating important pieces of evidence means relying on the ability of trained detection canines. Development of analytical technology to uncover and analyze evidence, potentially at the scene, could serve to expedite criminal investigations, searches, and court proceedings. To address this problem, a new technology based on gas sensor arrays was investigated for its applicability to forensic and law enforcement problems. The technology employs an array of sensors that respond to volatile chemical components yielding a characteristic `fingerprint` pattern representative of the vapor- phase composition of a sample. Sample aromas can be analyzed and identified using artificial neural networks that are trained on known aroma patterns. Several candidate applications based on known technological needs of the forensic and law enforcement communities have been investigated. These applications have included the detection of aromas emanating from cadavers to aid in determining time since death, drug detection for deterring the manufacture, sale, and use of drugs of abuse, and the analysis of fire debris for accelerant identification. The results to date for these applications have been extremely promising and demonstrate the potential applicability of this technology for forensic use.

  16. Workshop on the applications of new computer tools to thermal engineering; Applications a la thermique des nouveaux outils informatiques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-31

    This workshop on the applications of new computer tools to thermal engineering has been organized by the French society of thermal engineers. Seven papers have been presented, from which two papers dealing with thermal diffusivity measurements in materials and with the optimization of dryers have been selected for ETDE. (J.S.)

  17. Detecting cracks in aircraft engine fan blades using vibrothermography nondestructive evaluation

    International Nuclear Information System (INIS)

    Gao, Chunwang; Meeker, William Q.; Mayton, Donna

    2014-01-01

    Inspection is an important part of many maintenance processes, especially for safety-critical system components. This work was motivated by the need to develop more effective methods to detect cracks in rotating components of aircraft engines. This paper describes the analysis of data from vibrothermography inspections on aircraft engine turbine blades. Separate but similar analysis were done for two different purposes. In both analyses, we fit statistical models with random effects to describe the crack-to-crack variability and the effect that the experimental variables have on the responses. In the first analysis, the purpose of the study was to find vibrothermography equipment settings that will provide good crack detection capability over the population of similar cracks in the particular kind of aircraft engine turbine blades that were inspected. Then, the fitted model was used to determine the test conditions where the probability of detection (POD) is expected to be high and probability of alarm is expected to be low. In our second analysis, crack size information was added and a similar model was fit. This model provides an estimate of POD as a function of crack size for specified test conditions. This function is needed as an input to models for planning in-service inspection intervals. - Highlights: • Developed experimental design methods to optimize the inspection parameters for a vibrothermography inspection system. • Used mixed effects modeling to describe crack-to-crack variability. • Fit an extended model to provide estimates of the probability of detection as a function of crack length. • Investigated the coverage probability of confidence intervals for probability of detection

  18. Nanomaterials application in electrochemical detection of heavy metals

    International Nuclear Information System (INIS)

    Aragay, Gemma; Merkoçi, Arben

    2012-01-01

    Highlights: ► We review the recent trends in the application of nanomaterials for electrochemical detection of heavy metals. ► Different types of nanomaterials including metal nanoparticles, different carbon nanomaterials or nanochannels have been applied on the electrochemical analysis of heavy metals in various sensing formats/configurations. ► The great properties of nanomaterials allow the new devices to show advantages in terms of sensing performance (i.e. increase the sensitivity, decrease the detection limits and improve the stability). ► Between the various electrochemical techniques, voltammetric and potentiometric based ones are particularly taking interesting advantages by the incorporation of new nanomaterials due to the improved electrocatalytic properties beside the increase of the sensor's transducing area. - Abstract: Recent trends in the application of nanomaterials for electrochemical detection of heavy metals are shown. Various nanomaterials such as nanoparticles, nanowires, nanotubes, nanochannels, graphene, etc. have been explored either as modifiers of electrodes or as new electrode materials with interest to be applied in electrochemical stripping analysis, ion-selective detection, field-effect transistors or other indirect heavy metals (bio)detection alternatives. The developed devices have shown increased sensitivity and decreased detection limits between other improvements of analytical performance data. The phenomena behind nanomaterials responses are also discussed and some typical responses data of the developed systems either in standard solutions or in real samples are given. The developed nanomaterials based electrochemical systems are giving new inputs to the existing devices or leading to the development of novel heavy metal detection tools with interest for applications in field such as diagnostics, environmental and safety and security controls or other industries.

  19. Development and application of the ultrasonic technologies in nuclear engineering

    International Nuclear Information System (INIS)

    Lebedev, Nikolay; Krasilnikov, Dmitry; Vasiliev, Albert; Dubinin, Gennady; Yurmanov, Viktor

    2012-09-01

    Efficiency of some traditional chemical technologies in different areas could be significantly increased by adding ultrasonic treatment. For example, ultrasonic treatment was found to improve make-up water systems, decontamination procedures, etc. Improvement of traditional chemical technologies with implementation of ultrasonic treatment has allowed to significantly reducing water waste, including harmful species and radioactive products. The report shows the examples of the recent ultrasonic technology development and application in Russian nuclear engineering. They are as follows: - Preliminary cleaning of surfaces of in-pile parts (e.g. control sensors) prior to their assemblage and welding - Decontamination of grounds and metal surfaces of components with a complex structure -Decrease in sliding friction between fuel rods and grids during VVER reactor fuel assembly manufacturing -Removal of deposits from reactor fuel surfaces in VVER-440s -Increasing the density and strength of pressed sintered items while making fuel pellets and fuel elements, especially mixed-oxide fuel Surface cleanness is very important for the fuel assembly manufacturing, especially prior to welding. An ultrasonic technology for surface cleaning (from graphite and other lubricants, oxides etc.) was developed and implemented. The ultrasonic cleaning is applicable to the parts having both simple shape and different holes. Ultrasonic technology has allowed to improve the surface quality and environmental safety. Ultrasonic treatment appears to be expedient to intensify the chemical decontamination of solid radioactive waste from grounds of different fractions to metallic components. Ultrasonic treatment reduces the decontamination process duration up to 100 times as much. Excellent decontamination factor was received even for the ground fractions below 1 mm. It should be noted that alternative decontamination techniques (e.g. hydraulic separation) are poorly applicable for such ground

  20. Exploring Permission-Induced Risk in Android Applications for Malicious Application Detection

    KAUST Repository

    Wang, Wei; Wang, Xing; Feng, Dawei; Liu, Jiqiang; Han, Zhen; Zhang, Xiangliang

    2014-01-01

    Android has been a major target of malicious applications (malapps). How to detect and keep the malapps out of the app markets is an ongoing challenge. One of the central design points of Android security mechanism is permission control

  1. Incorporating unnatural amino acids to engineer biocatalysts for industrial bioprocess applications.

    Science.gov (United States)

    Ravikumar, Yuvaraj; Nadarajan, Saravanan Prabhu; Hyeon Yoo, Tae; Lee, Chong-Soon; Yun, Hyungdon

    2015-12-01

    The bioprocess engineering with biocatalysts broadly spans its development and actual application of enzymes in an industrial context. Recently, both the use of bioprocess engineering and the development and employment of enzyme engineering techniques have been increasing rapidly. Importantly, engineering techniques that incorporate unnatural amino acids (UAAs) in vivo has begun to produce enzymes with greater stability and altered catalytic properties. Despite the growth of this technique, its potential value in bioprocess applications remains to be fully exploited. In this review, we explore the methodologies involved in UAA incorporation as well as ways to synthesize these UAAs. In addition, we summarize recent efforts to increase the yield of UAA engineered proteins in Escherichia coli and also the application of this tool in enzyme engineering. Furthermore, this protein engineering tool based on the incorporation of UAA can be used to develop immobilized enzymes that are ideal for bioprocess applications. Considering the potential of this tool and by exploiting these engineered enzymes, we expect the field of bioprocess engineering to open up new opportunities for biocatalysis in the near future. Copyright © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Optical system for CO and NO gas detection in the exhaust manifold of combustion engines

    International Nuclear Information System (INIS)

    Mello, M.; De Vittorio, M.; Passaseo, A.; Lomascolo, M.; De Risi, A.

    2007-01-01

    The experimental characterization of an innovative optical system for detection of carbon monoxide (CO) and nitride oxide (NO) in the exhaust manifold of otto and diesel engines is reported. A photodetector based on gallium nitride (GaN) and an UV light source are integrated in a chamber of analysis and form the detection system. The UV light source, consisting of a spark produced by an arc discharge, induces electronic transitions in the gas molecules flowing between the light source and the GaN photodetector. The transitions modify the fraction of light in the UV spectral region which is detected by the GaN photodetector, as a function of the species concentration. By means of its structural properties, gallium nitride (GaN) allows to operate at high temperature and high speed and to work in situ in the exhaust manifold of combustion engines at temperatures as high as 600 o C, at which the deposited organic residuals on the detector can be oxidized. This assures a clear surface necessary for a real time optical measurement of the species concentration to be used for a closed loop control of the fuel injection process. The system was applied to the detection of CO and NO with concentration between 0% and 2% in a buffer of pure nitrogen gas, showing an increase in the measured photocurrent as a function of the above gases

  3. Ceramic applications in the advanced Stirling automotive engine

    Science.gov (United States)

    Tomazic, W. A.; Cairelli, J. E.

    1978-01-01

    The requirements of the ideal Stirling cycle, as well as basic types of practical engines are described. Advantages, disadvantages, and problem areas of these Stirling engines are discussed. The potential for ceramic components is also considered. Currently ceramics are used in only two areas, the air preheater and insulating tiles between the burner and the heater head. For the advanced Stirling engine to achieve high efficiency and low cost, the principal components are expected to be made from ceramic materials, including the heater head, air preheater, regenerator, the burner and the power piston. Supporting research and technology programs for ceramic component development are briefly described.

  4. Application of Modern Simulation Technology in Mechanical Outstanding Engineer Training

    Directory of Open Access Journals (Sweden)

    Gongfa Li

    2014-03-01

    Full Text Available This text has described the relationship between outstanding engineer training and modern simulation technology, have recommended the characteristics of mechanical outstanding engineer in detail. Aiming at the importance of the teaching practice link to course of theory of mechanics, mechanical design and mechanical signal analysis, have expounded the function of modern simulation technology in the mechanical outstanding engineer training, especially on teaching practice in the theory of mechanics, mechanical design and mechanical signal analysis. It has the advantages of economizing the teaching cost, overcoming the hardware constrains, model prediction, promoting student's innovation and manipulative ability, so can popularize and develop in a more cost-effective manner in the university.

  5. Advances in fractional calculus theoretical developments and applications in physics and engineering

    CERN Document Server

    Sabatier, J; Machado, J A Teneiro

    2007-01-01

    Fractional Calculus is a new growing field. Up to this point, researchers, scientists, and engineers have been reluctant to accept the fact that Fractional Calculus can be used in the analysis and design of many systems of practical interests, whereas in similar applications the traditional calculus either fails or provides poor solutionsMany engineers, scientists, and applied mathematicians are looking for books that can provide many applications of Fractional Calculus. This book will provide a partial solution to this problem. Since it covers recent applications of Fractional Calculus, it will be attractive to many engineers, scientists, and applied mathematicians.

  6. Surfing the Edge of Chaos: Applications to Software Engineering

    National Research Council Canada - National Science Library

    Nogueira, Juan C; Jones, Carl

    2000-01-01

    .... We discuss the feasibility of using this theory in software engineering as an alternative to bureaucratic software development processes. We present also some recommendations that could help to acquire competitive advantage in software development, hence achieve information superiority.

  7. Reaming process improvement and control: An application of statistical engineering

    DEFF Research Database (Denmark)

    Müller, Pavel; Genta, G.; Barbato, G.

    2012-01-01

    A reaming operation had to be performed within given technological and economical constraints. Process improvement under realistic conditions was the goal of a statistical engineering project, supported by a comprehensive experimental investigation providing detailed information on single...

  8. Final report : evaluation of microcomputer applications in transportation engineering.

    Science.gov (United States)

    1984-01-01

    This study investigated areas where microcomputers can aid in the effectiveness of transportation engineering at state and local levels. A survey of the microcomputer needs of transportation professionals in state and local agencies in Virginia was c...

  9. Impedance-based monitoring for tissue engineering applications

    DEFF Research Database (Denmark)

    Canali, Chiara; Heiskanen, Arto; Martinsen, Ø.G.

    2015-01-01

    Impedance is a promising technique for sensing the overall process of tissue engineering. Different electrode configurations can be used to characterize the scaffold that supports cell organization in terms of hydrogel polymerization and degree of porosity, monitoring cell loading, cell...

  10. Irreversible thermodynamic analysis and application for molecular heat engines

    Science.gov (United States)

    Lucia, Umberto; Açıkkalp, Emin

    2017-09-01

    Is there a link between the macroscopic approach to irreversibility and microscopic behaviour of the systems? Consumption of free energy keeps the system away from a stable equilibrium. Entropy generation results from the redistribution of energy, momentum, mass and charge. This concept represents the essence of the thermodynamic approach to irreversibility. Irreversibility is the result of the interaction between systems and their environment. The aim of this paper is to determine lost works in a molecular engine and compare results with macro (classical) heat engines. Firstly, irreversible thermodynamics are reviewed for macro and molecular cycles. Secondly, irreversible thermodynamics approaches are applied for a quantum heat engine with -1/2 spin system. Finally, lost works are determined for considered system and results show that macro and molecular heat engines obey same limitations. Moreover, a quantum thermodynamic approach is suggested in order to explain the results previously obtained from an atomic viewpoint.

  11. Engineering protein scaffolds for protein separation, biocatalysis and nanotechnology applications

    Science.gov (United States)

    Liu, Fang

    -coordinating function impaired was used in replace of the original full length dockerin domain. The truncated dockerin domain maintained its functionality as an effective affinity tag, and efficient EDTA mediated dissociation of the bound dockerin-intein tag was also realized. The regenerated ELP capturing scaffold was reused for additional purification cycles without any decrease in efficiency. The second objective was to assemble biocatalysts for biofuel cells. Three beta-NAD dependent dehydrogenases, alcohol dehydrogenase (ADH), formaldehyde dehydrogenase (FALDH) and formate dehydrogenase (FDH), were site-specifically co-localized onto the scaffolds displayed on the yeast surface based on the high-affinity interactions between three orthogonal cohesin/dockerin pairs. The assembled multi-enzyme cascades, which can completely convert methanol to CO2, showed improved production yield compared with that of the non-complexed enzyme mixture, indicating efficient substrate channeling among the three enzymes. This strategy can be easily extended to other complex cascade reactions for enzymatic fuel cell applications. To further explore the role of biotechnology toward environmental sustainability, Escherichia coli was engineered to express phytochelatin synthase, which converted glutathione into the metal-binding peptide phytochelatin (PC). PCs served as peptide scaffolds and mediated synthesis of CdS nanocrystals. This approach may be generalized to guide the in vitro self-assembly of a wide range of nanocrystals with different compositions and sizes.

  12. Prototype of Intrusion Detection Model using UML 5.0 and Forward Engineering

    Directory of Open Access Journals (Sweden)

    Muthaiyan MADIAJAGAN,

    2011-01-01

    Full Text Available In this paper we are using UML (Unified Modeling Language which is the blueprint language between the programmers, analysts, and designer’s for easy representation of pictures or diagrammatic notation with some textual data. Here we are using UML 5.0 to show “prototype of the Intrusion Detection Model” and by explaining it by combining various parts by drawing various UML diagrams such as Use cases and Activity diagrams and Class Diagram using which we show forward engineering using the class diagram of the IDM( Intrusion Detection Model. IDM is a device or software that works on detecting malicious activities by unauthorized users that can cause breach to the security policy within a network.

  13. A Model-Free Diagnosis Approach for Intake Leakage Detection and Characterization in Diesel Engines

    Directory of Open Access Journals (Sweden)

    Ghaleb Hoblos

    2015-07-01

    Full Text Available Feature selection is an essential step for data classification used in fault detection and diagnosis processes. In this work, a new approach is proposed, which combines a feature selection algorithm and a neural network tool for leak detection and characterization tasks in diesel engine air paths. The Chi square classifier is used as the feature selection algorithm and the neural network based on Levenberg-Marquardt is used in system behavior modeling. The obtained neural network is used for leak detection and characterization. The model is learned and validated using data generated by xMOD. This tool is used again for testing. The effectiveness of the proposed approach is illustrated in simulation when the system operates on a low speed/load and the considered leak affecting the air path is very small.

  14. The application of the detection filter to aircraft control surface and actuator failure detection and isolation

    Science.gov (United States)

    Bonnice, W. F.; Wagner, E.; Motyka, P.; Hall, S. R.

    1985-01-01

    The performance of the detection filter in detecting and isolating aircraft control surface and actuator failures is evaluated. The basic detection filter theory assumption of no direct input-output coupling is violated in this application due to the use of acceleration measurements for detecting and isolating failures. With this coupling, residuals produced by control surface failures may only be constrained to a known plane rather than to a single direction. A detection filter design with such planar failure signatures is presented, with the design issues briefly addressed. In addition, a modification to constrain the residual to a single known direction even with direct input-output coupling is also presented. Both the detection filter and the modification are tested using a nonlinear aircraft simulation. While no thresholds were selected, both filters demonstrated an ability to detect control surface and actuator failures. Failure isolation may be a problem if there are several control surfaces which produce similar effects on the aircraft. In addition, the detection filter was sensitive to wind turbulence and modeling errors.

  15. Few molecule SERS detection using nanolens based plasmonic nanostructure: application to point mutation detection

    KAUST Repository

    Das, Gobind

    2016-10-27

    Advancements in nanotechnology fabrication techniques allow the possibility to design and fabricate a device with a minimum gap (<10 nm) between the composing nanostructures in order to obtain better control over the creation and spatial definition of plasmonic hot-spots. The present study is intended to show the fabrication of nanolens and their application to single/few molecules detection. Theoretical simulations were performed on different designs of real structures, including comparison of rough and smooth surfaces. Various molecules (rhodamine 6G, benzenethiol and BRCA1/BRCT peptides) were examined in this regard. Single molecule detection was possible for synthetic peptides, with a possible application in early detection of diseases. © The Royal Society of Chemistry.

  16. Few molecule SERS detection using nanolens based plasmonic nanostructure: application to point mutation detection

    KAUST Repository

    Das, Gobind; Alrasheed, Salma; Coluccio, Maria Laura; Gentile, Francesco; Nicastri, Annalisa; Candeloro, Patrizio; Cuda, Giovanni; Perozziello, Gerardo; Di Fabrizio, Enzo M.

    2016-01-01

    Advancements in nanotechnology fabrication techniques allow the possibility to design and fabricate a device with a minimum gap (<10 nm) between the composing nanostructures in order to obtain better control over the creation and spatial definition of plasmonic hot-spots. The present study is intended to show the fabrication of nanolens and their application to single/few molecules detection. Theoretical simulations were performed on different designs of real structures, including comparison of rough and smooth surfaces. Various molecules (rhodamine 6G, benzenethiol and BRCA1/BRCT peptides) were examined in this regard. Single molecule detection was possible for synthetic peptides, with a possible application in early detection of diseases. © The Royal Society of Chemistry.

  17. The application of learning skills in an engineering programme

    OpenAIRE

    Shoemaker, Leslie

    2006-01-01

    At the Dublin Institute of Technology, an engineering programme in the School of Control Systems and Electrical Engineering has successfully incorporated a study skills module into the core curriculum. The module, titled Academic Development and Key Skills, is part of the first year of the programme and has a two-fold purpose. Primarily the goal is to assist the students with the transition from second level education to third level by teaching them a more competent learning style. This, in t...

  18. Application of image processing technology in yarn hairiness detection

    Directory of Open Access Journals (Sweden)

    Guohong ZHANG

    2016-02-01

    Full Text Available Digital image processing technology is one of the new methods for yarn detection, which can realize the digital characterization and objective evaluation of yarn appearance. This paper overviews the current status of development and application of digital image processing technology used for yarn hairiness evaluation, and analyzes and compares the traditional detection methods and this new developed method. Compared with the traditional methods, the image processing technology based method is more objective, fast and accurate, which is the vital development trend of the yarn appearance evaluation.

  19. Molecular engineering of two-photon fluorescent probes for bioimaging applications

    Science.gov (United States)

    Liu, Hong-Wen; Liu, Yongchao; Wang, Peng; Zhang, Xiao-Bing

    2017-03-01

    During the past two decades, two-photon microscopy (TPM), which utilizes two near-infrared photons as the excitation source, has emerged as a novel, attractive imaging tool for biological research. Compared with one-photon microscopy, TPM offers several advantages, such as lowering background fluorescence in living cells and tissues, reducing photodamage to biosamples, and a photobleaching phenomenon, offering better 3D spatial localization, and increasing penetration depth. Small-molecule-based two-photon fluorescent probes have been well developed for the detection and imaging of various analytes in biological systems. In this review, we will give a general introduction of molecular engineering of two-photon fluorescent probes based on different fluorescence response mechanisms for bioimaging applications during the past decade. Inspired by the desired advantages of small-molecule two-photon fluorescent probes in biological imaging applications, we expect that more attention will be devoted to the development of new two-photon fluorophores and applications of TPM in areas of bioanalysis and disease diagnosis.

  20. Structural Damage Detection Using Changes in Natural Frequencies: Theory and Applications

    Science.gov (United States)

    He, K.; Zhu, W. D.

    2011-07-01

    A vibration-based method that uses changes in natural frequencies of a structure to detect damage has advantages over conventional nondestructive tests in detecting various types of damage, including loosening of bolted joints, using minimum measurement data. Two major challenges associated with applications of the vibration-based damage detection method to engineering structures are addressed: accurate modeling of structures and the development of a robust inverse algorithm to detect damage, which are defined as the forward and inverse problems, respectively. To resolve the forward problem, new physics-based finite element modeling techniques are developed for fillets in thin-walled beams and for bolted joints, so that complex structures can be accurately modeled with a reasonable model size. To resolve the inverse problem, a logistical function transformation is introduced to convert the constrained optimization problem to an unconstrained one, and a robust iterative algorithm using a trust-region method, called the Levenberg-Marquardt method, is developed to accurately detect the locations and extent of damage. The new methodology can ensure global convergence of the iterative algorithm in solving under-determined system equations and deal with damage detection problems with relatively large modeling error and measurement noise. The vibration-based damage detection method is applied to various structures including lightning masts, a space frame structure and one of its components, and a pipeline. The exact locations and extent of damage can be detected in the numerical simulation where there is no modeling error and measurement noise. The locations and extent of damage can be successfully detected in experimental damage detection.

  1. Structural Damage Detection Using Changes in Natural Frequencies: Theory and Applications

    International Nuclear Information System (INIS)

    He, K; Zhu, W D

    2011-01-01

    A vibration-based method that uses changes in natural frequencies of a structure to detect damage has advantages over conventional nondestructive tests in detecting various types of damage, including loosening of bolted joints, using minimum measurement data. Two major challenges associated with applications of the vibration-based damage detection method to engineering structures are addressed: accurate modeling of structures and the development of a robust inverse algorithm to detect damage, which are defined as the forward and inverse problems, respectively. To resolve the forward problem, new physics-based finite element modeling techniques are developed for fillets in thin-walled beams and for bolted joints, so that complex structures can be accurately modeled with a reasonable model size. To resolve the inverse problem, a logistical function transformation is introduced to convert the constrained optimization problem to an unconstrained one, and a robust iterative algorithm using a trust-region method, called the Levenberg-Marquardt method, is developed to accurately detect the locations and extent of damage. The new methodology can ensure global convergence of the iterative algorithm in solving under-determined system equations and deal with damage detection problems with relatively large modeling error and measurement noise. The vibration-based damage detection method is applied to various structures including lightning masts, a space frame structure and one of its components, and a pipeline. The exact locations and extent of damage can be detected in the numerical simulation where there is no modeling error and measurement noise. The locations and extent of damage can be successfully detected in experimental damage detection.

  2. Situational Requirements Engineering for the Development of Content Management System-based Web Applications

    NARCIS (Netherlands)

    Souer, J.; van de Weerd, I.; Versendaal, J.M.; Brinkkemper, S.

    2005-01-01

    Web applications are evolving towards strong content-centered Web applications. The development processes and implementation of these applications are unlike the development and implementation of traditional information systems. In this paper we propose WebEngineering Method; a method for developing

  3. Research on engineering-oriented constraints conflict detection in collaborative design of wire harness technology

    Institute of Scientific and Technical Information of China (English)

    LIU Xiaoping; HE Honglin; XU Benzhu

    2012-01-01

    Engineering-oriented constraint of harness technology has much information and project information presents progressive changes along with the design. Therefore, how to handle conflict resolution quickly is a problem to be solved. Process model of con- flict detection is put forward according to characteristics of harness technology design engineering-oriented constraint, and then two problems of how to conduct conflict positioning and judgment of constraint rules are introduced in this paper. Afterwards in this pa- per, constraint information directed acyclic graph is established by classified project constraint information to solve the conflict posi- tioning problem; solution of constraint satisfaction problem is applied to realize judgment problem of constraint rules. Finally, exam- ple is used to analyze the method in this paper to further verify the correctness and effectiveness of this method.

  4. Knock investigation by flame and radical species detection in spark ignition engine for different fuels

    International Nuclear Information System (INIS)

    Merola, Simona S.; Vaglieco, Bianca M.

    2007-01-01

    The present paper aims to evaluate the phenomena of normal combustion and knocking in a single cylinder, ported fuel injection, four-stroke spark-ignition engine with a four-valve production head. All the measurements were realized in an optically accessible engine equipped with a wide quartz window in the bottom of the chamber. The study was carried out using optical techniques based on flame natural emission imaging and spectroscopy from UV to visible. Radical species such as OH and HCO were detected and correlated to the onset and the duration of knock and presence of hot-spots in end-gas. Measurements were carried out at 1000 rpm with wide-open throttle and stoichiometric mixture. Pure iso-octane, suitable mixtures of iso-octane and n-heptane and commercial gasoline were used

  5. Chemical Reaction Engineering Applications in Non-traditional Technologies. A Textbook Supplement.

    Science.gov (United States)

    Savage, Phillip E.; Blaine, Steven

    1991-01-01

    A set of educational materials that have been developed which deal with chemical engineering applications in emerging technologies is described. The organization and the content of the supplemental textbook materials and how they can be integrated into an undergraduate reaction engineering course are discussed. (KR)

  6. Application of wear resistant spraying for diesel engine; Diesel kikan eno taimamo yosha no tekiyo

    Energy Technology Data Exchange (ETDEWEB)

    Kitajima, Y. [Mitsui Engineering and Shipbuliding Co. Ltd., Tokyo (Japan)

    1999-03-31

    Diesel engines used widely as propelling engines of ships have increasingly been provided with a high output and a high thermal efficiency; their structural members, particularly, the component parts for combustion chambers are therefore used under severe conditions, giving rise to the need of surface treatment and surface reforming of the members. Parts for marine diesel engines are huge, so that the technology applicable to the surface treatment and reforming are limited in point of facility and cost; therefore, most suitable is thermal spraying. This paper primarily discusses, among marine diesel engines, a 2-cycle low-speed engine with a 260-980mm bore used for the main engine of a merchant ship such as a container ship, bulk carrier or a tanker, and a 4-cycle medium-speed engine with a 300-420mm bore used for the main engine of a naval vessel; the paper explains the application status of a thermal spraying technology which is in progress to cope with the high output and high thermal efficiency of the diesel engines, explaining particularly the story of the development and the technological features of the wear resistant thermal spraying, which has been put to practical use, on the cylinder liner and the piston ring of the 4-cycle medium-speed engine. (NEDO)

  7. Damage detection of engine bladed-disks using multivariate statistical analysis

    Science.gov (United States)

    Fang, X.; Tang, J.

    2006-03-01

    The timely detection of damage in aero-engine bladed-disks is an extremely important and challenging research topic. Bladed-disks have high modal density and, particularly, their vibration responses are subject to significant uncertainties due to manufacturing tolerance (blade-to-blade difference or mistuning), operating condition change and sensor noise. In this study, we present a new methodology for the on-line damage detection of engine bladed-disks using their vibratory responses during spin-up or spin-down operations which can be measured by blade-tip-timing sensing technique. We apply a principle component analysis (PCA)-based approach for data compression, feature extraction, and denoising. The non-model based damage detection is achieved by analyzing the change between response features of the healthy structure and of the damaged one. We facilitate such comparison by incorporating the Hotelling's statistic T2 analysis, which yields damage declaration with a given confidence level. The effectiveness of the method is demonstrated by case studies.

  8. Fault Diagnosis of Internal Combustion Engine Valve Clearance Using the Impact Commencement Detection Method

    Science.gov (United States)

    Jiang, Zhinong; Wang, Zijia; Zhang, Jinjie

    2017-01-01

    Internal combustion engines (ICEs) are widely used in many important fields. The valve train clearance of an ICE usually exceeds the normal value due to wear or faulty adjustment. This work aims at diagnosing the valve clearance fault based on the vibration signals measured on the engine cylinder heads. The non-stationarity of the ICE operating condition makes it difficult to obtain the nominal baseline, which is always an awkward problem for fault diagnosis. This paper overcomes the problem by inspecting the timing of valve closing impacts, of which the referenced baseline can be obtained by referencing design parameters rather than extraction during healthy conditions. To accurately detect the timing of valve closing impact from vibration signals, we carry out a new method to detect and extract the commencement of the impacts. The results of experiments conducted on a twelve-cylinder ICE test rig show that the approach is capable of extracting the commencement of valve closing impact accurately and using only one feature can give a superior monitoring of valve clearance. With the help of this technique, the valve clearance fault becomes detectable even without the comparison to the baseline, and the changing trend of the clearance could be trackable. PMID:29244722

  9. Fault Diagnosis of Internal Combustion Engine Valve Clearance Using the Impact Commencement Detection Method.

    Science.gov (United States)

    Jiang, Zhinong; Mao, Zhiwei; Wang, Zijia; Zhang, Jinjie

    2017-12-15

    Internal combustion engines (ICEs) are widely used in many important fields. The valve train clearance of an ICE usually exceeds the normal value due to wear or faulty adjustment. This work aims at diagnosing the valve clearance fault based on the vibration signals measured on the engine cylinder heads. The non-stationarity of the ICE operating condition makes it difficult to obtain the nominal baseline, which is always an awkward problem for fault diagnosis. This paper overcomes the problem by inspecting the timing of valve closing impacts, of which the referenced baseline can be obtained by referencing design parameters rather than extraction during healthy conditions. To accurately detect the timing of valve closing impact from vibration signals, we carry out a new method to detect and extract the commencement of the impacts. The results of experiments conducted on a twelve-cylinder ICE test rig show that the approach is capable of extracting the commencement of valve closing impact accurately and using only one feature can give a superior monitoring of valve clearance. With the help of this technique, the valve clearance fault becomes detectable even without the comparison to the baseline, and the changing trend of the clearance could be trackable.

  10. DETECT: a MATLAB toolbox for event detection and identification in time series, with applications to artifact detection in EEG signals.

    Science.gov (United States)

    Lawhern, Vernon; Hairston, W David; Robbins, Kay

    2013-01-01

    Recent advances in sensor and recording technology have allowed scientists to acquire very large time-series datasets. Researchers often analyze these datasets in the context of events, which are intervals of time where the properties of the signal change relative to a baseline signal. We have developed DETECT, a MATLAB toolbox for detecting event time intervals in long, multi-channel time series. Our primary goal is to produce a toolbox that is simple for researchers to use, allowing them to quickly train a model on multiple classes of events, assess the accuracy of the model, and determine how closely the results agree with their own manual identification of events without requiring extensive programming knowledge or machine learning experience. As an illustration, we discuss application of the DETECT toolbox for detecting signal artifacts found in continuous multi-channel EEG recordings and show the functionality of the tools found in the toolbox. We also discuss the application of DETECT for identifying irregular heartbeat waveforms found in electrocardiogram (ECG) data as an additional illustration.

  11. DETECT: a MATLAB toolbox for event detection and identification in time series, with applications to artifact detection in EEG signals.

    Directory of Open Access Journals (Sweden)

    Vernon Lawhern

    Full Text Available Recent advances in sensor and recording technology have allowed scientists to acquire very large time-series datasets. Researchers often analyze these datasets in the context of events, which are intervals of time where the properties of the signal change relative to a baseline signal. We have developed DETECT, a MATLAB toolbox for detecting event time intervals in long, multi-channel time series. Our primary goal is to produce a toolbox that is simple for researchers to use, allowing them to quickly train a model on multiple classes of events, assess the accuracy of the model, and determine how closely the results agree with their own manual identification of events without requiring extensive programming knowledge or machine learning experience. As an illustration, we discuss application of the DETECT toolbox for detecting signal artifacts found in continuous multi-channel EEG recordings and show the functionality of the tools found in the toolbox. We also discuss the application of DETECT for identifying irregular heartbeat waveforms found in electrocardiogram (ECG data as an additional illustration.

  12. Fault Detection based on MCSA for a 400Hz Asynchronous Motor for Airborne Applications

    Directory of Open Access Journals (Sweden)

    Steffen Haus

    2013-01-01

    Full Text Available Future health monitoring concepts in different fields of engineering require reliable fault detection to avoid unscheduled machine downtime. Diagnosis of electrical induction machines for industrial applications is widely discussed in literature. In aviation industry, this topic is still only rarely discussed.A common approach to health monitoring for electrical induction machines is to use Motor Current Signature Analysis (MCSA based on a Fast Fourier Transform (FFT. Research results on this topic are available for comparatively large motors, where the power supply is typically based on 50Hz alternating current, which is the general power supply frequency for industrial applications.In this paper, transferability to airborne applications, where the power supply is 400Hz, is assessed. Three phase asynchronous motors are used to analyse detectability of different motor faults. The possibility to transfer fault detection results from 50Hz to 400Hz induction machines is the main question answered in this research work. 400Hz power supply frequency requires adjusted motor design, causing increased motor speed compared to 50Hz supply frequency. The motor used for experiments in this work is a 800W motor with 200V phase to phase power supply, powering an avionic fan. The fault cases to be examined are a bearing fault, a rotor unbalance, a stator winding fault, a broken rotor bar and a static air gap eccentricity. These are the most common faults in electrical induction machines which can cause machine downtime. The focus of the research work is the feasibility of the application of MCSA for small scale, high speed motor design, using the Fourier spectra of the current signal.Detectability is given for all but the bearing fault, although rotor unbalance can only be detected in case of severe damage level. Results obtained in the experiments are interpreted with respect to the motor design. Physical interpretation are given in case the results differ

  13. Laser desorption mass spectrometry for biomolecule detection and its applications

    Science.gov (United States)

    Winston Chen, C. H.; Sammartano, L. J.; Isola, N. R.; Allman, S. L.

    2001-08-01

    During the past few years, we developed and used laser desorption mass spectrometry for biomolecule detections. Matrix-assisted laser desorption/ionization (MALDI) was successfully used to detect DNA fragments with the size larger than 3000 base pairs. It was also successfully used to sequence DNA with both enzymatic and chemical degradation methods to produce DNA ladders. We also developed MALDI with fragmentation for direct DNA sequencing for short DNA probes. Since laser desorption mass spectrometry for DNA detection has the advantages of fast speed and no need of labeling, it has a great potential for molecular diagnosis for disease and person identification by DNA fingerprinting. We applied laser desorption mass spectrometry to succeed in the diagnosis of cystic fibrosis and several other nerve degenerative diseases such as Huntington's disease. We also succeeded in demonstrating DNA typing for forensic applications.

  14. Laser desorption mass spectrometry for biomolecule detection and its applications

    International Nuclear Information System (INIS)

    Winston Chen, C.H.; Allman, S.L.; Sammartano, L.J.; Isola, N.R.

    2001-01-01

    During the past few years, we developed and used laser desorption mass spectrometry for biomolecule detections. Matrix-assisted laser desorption/ionization (MALDI) was successfully used to detect DNA fragments with the size larger than 3000 base pairs. It was also successfully used to sequence DNA with both enzymatic and chemical degradation methods to produce DNA ladders. We also developed MALDI with fragmentation for direct DNA sequencing for short DNA probes. Since laser desorption mass spectrometry for DNA detection has the advantages of fast speed and no need of labeling, it has a great potential for molecular diagnosis for disease and person identification by DNA fingerprinting. We applied laser desorption mass spectrometry to succeed in the diagnosis of cystic fibrosis and several other nerve degenerative diseases such as Huntington's disease. We also succeeded in demonstrating DNA typing for forensic applications

  15. Synthesis of cracked Calophyllum inophyllum oil using fly ash catalyst for diesel engine application

    KAUST Repository

    Muthukumaran, N.; Saravanan, Chinnusamy G.; Prasanna Raj Yadav, S.; Vallinayagam, R.; Vedharaj, S.; Roberts, William L.

    2015-01-01

    In this study, production of hydrocarbon fuel from Calophyllum inophyllum oil has been characterized for diesel engine application, by appraising essential fuel processing parameters. As opposed to traditional trans-esterification process

  16. Activities of the Institute for Computer Applications in Science and Engineering (ICASE)

    Science.gov (United States)

    1988-01-01

    This report summarizes research conducted at the Institute for Computer Applications Science and Engineering in applied mathematics, numerical analysis, and computer science during the period October 2, 1987 through March 31, 1988.

  17. [Research Conducted at the Institute for Computer Applications in Science and Engineering

    Science.gov (United States)

    1997-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, fluid mechanics, and computer science during the period 1 Oct. 1996 - 31 Mar. 1997.

  18. Research in progress at the Institute for Computer Applications in Science and Engineering

    Science.gov (United States)

    1987-01-01

    This report summarizes research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis, and computer science during the period April 1, 1987 through October 1, 1987.

  19. Activities of the Institute for Computer Applications in Science and Engineering

    Science.gov (United States)

    1985-01-01

    Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis, and computer science during the period April 1, 1985 through October 2, 1985 is summarized.

  20. An overview of interactive computer graphics and its application to computer-aided engineering and design

    International Nuclear Information System (INIS)

    Van Dam, A.

    1983-01-01

    The purpose of this brief birds-eye view of interactive graphics is to list the key ideas, and to show how one of the most important application areas, Computer Aided Engineering/Design takes advantage of it. (orig.)

  1. [Optimized application of nested PCR method for detection of malaria].

    Science.gov (United States)

    Yao-Guang, Z; Li, J; Zhen-Yu, W; Li, C

    2017-04-28

    Objective To optimize the application of the nested PCR method for the detection of malaria according to the working practice, so as to improve the efficiency of malaria detection. Methods Premixing solution of PCR, internal primers for further amplification and new designed primers that aimed at two Plasmodium ovale subspecies were employed to optimize the reaction system, reaction condition and specific primers of P . ovale on basis of routine nested PCR. Then the specificity and the sensitivity of the optimized method were analyzed. The positive blood samples and examination samples of malaria were detected by the routine nested PCR and the optimized method simultaneously, and the detection results were compared and analyzed. Results The optimized method showed good specificity, and its sensitivity could reach the pg to fg level. The two methods were used to detect the same positive malarial blood samples simultaneously, the results indicated that the PCR products of the two methods had no significant difference, but the non-specific amplification reduced obviously and the detection rates of P . ovale subspecies improved, as well as the total specificity also increased through the use of the optimized method. The actual detection results of 111 cases of malarial blood samples showed that the sensitivity and specificity of the routine nested PCR were 94.57% and 86.96%, respectively, and those of the optimized method were both 93.48%, and there was no statistically significant difference between the two methods in the sensitivity ( P > 0.05), but there was a statistically significant difference between the two methods in the specificity ( P PCR can improve the specificity without reducing the sensitivity on the basis of the routine nested PCR, it also can save the cost and increase the efficiency of malaria detection as less experiment links.

  2. Advanced materials for aircraft engine applications. Koku engine yo zairyo no doko

    Energy Technology Data Exchange (ETDEWEB)

    1994-05-01

    The thrust/weight ratio which is thrust per unit weight of engine is a parameter of aircraft engine performance. With a mean material density of 6.6g/cm[sup 3], some of the supersonic plane engines are 7.9 in thrust/weight ratio. Its attaining 20 is predicted by some reports. The turbine inlet temperature is a parameter of engine temperature heightening exceeds 1400[degree]C. Its attaining 2000[degree]C in the 21st century is also predicted by some reports. By dividing the aircraft engine materials into both improvement and innovation material systems, the present paper explained the characteristics and present status of materials, and how to put them in practical use. As an improvement material, titanium alloy, nickel base alloy and resinous composite materials were exhibited with examples of having improved the established material system in performance and cost. Used as a turbine vane member, the nickel base alloy contributes, as a unidirectional coagulation alloy, single crystal alloy and oxide dispersion exciting alloy, to the creep resistance strengthening at high temperatures against the fatigue due to thermal strain. It is also explained how to put TiAl and FRM to practical use. 8 refs., 13 figs., 2 tabs.

  3. Can a novel smartphone application detect periodic limb movements?

    Science.gov (United States)

    Bhopi, Rashmi; Nagy, David; Erichsen, Daniel

    2012-01-01

    Periodic limb movements (PLMs) are repetitive, stereotypical and unconscious movements, typically of the legs, that occur in sleep and are associated with several sleep disorders. The gold standard for detecting PLMs is overnight electromyography which, although highly sensitive and specific, is time and labour consuming. The current generation of smart phones is equipped with tri-axial accelerometers that record movement. To develop a smart phone application that can detect PLMs remotely. A leg movement sensing application (LMSA) was programmed in iOS 5x and incorporated into an iPhone 4S (Apple INC.). A healthy adult male subject underwent simultaneous EMG and LMSA measurements of voluntary stereotypical leg movements. The mean number of leg movements recorded by EMG and by the LMSA was compared. A total of 403 leg movements were scored by EMG of which the LMSA recorded 392 (97%). There was no statistical difference in mean number of leg movements recorded between the two modalities (p = 0.3). These preliminary results indicate that a smart phone application is able to accurately detect leg movements outside of the hospital environment and may be a useful tool for screening and follow up of patients with PLMs.

  4. The self-assembling process and applications in tissue engineering

    Science.gov (United States)

    Lee, Jennifer K.; Link, Jarrett M.; Hu, Jerry C. Y.; Athanasiou, Kyriacos A.

    2018-01-01

    Tissue engineering strives to create neotissues capable of restoring function. Scaffold-free technologies have emerged that can recapitulate native tissue function without the use of an exogenous scaffold. This chapter will survey, in particular, the self-assembling and self-organization processes as scaffold-free techniques. Characteristics and benefits of each process are described, and key examples of tissues created using these scaffold-free processes are examined to provide guidance for future tissue engineering developments. This chapter aims to explore the potential of self-assembly and self-organization scaffold-free approaches, detailing the recent progress in the in vitro tissue engineering of biomimetic tissues with these methods, toward generating functional tissue replacements. PMID:28348174

  5. The Application of Corals in Bone Tissue Engineering

    Directory of Open Access Journals (Sweden)

    Iraj Nabipour

    2017-05-01

    Full Text Available Natural coral exoskeleton and coralline hydroxyapatite have been used as bone replacement graft for repairing of bone defects in animal models and humans since two decades ago. These bone replacement grafts have an osteoconductive, biodegradable and biocompatible features. Currently, three lines of researches in bone tissue engineering are conducting on corals. Corals have been used for construction of bony composites, stem cells attachments, and the growth factors-scaffold-based approaches. This review have paid to the wide range of coral use in clinical experiments as a bone graft substitute and cell-scaffold-based approaches in bone tissue engineering.

  6. Application of reverse engineering in the medical industry.

    Science.gov (United States)

    Kaleev, A. A.; Kashapov, L. N.; Kashapov, N. F.; Kashapov, R. N.

    2017-09-01

    The purpose of this research is to develop on the basis of existing analogs new design of ophthalmologic microsurgical tweezers by using reverse engineering techniques. Virtual model was obtained by using a three-dimensional scanning system Solutionix Rexcan 450 MP. Geomagic Studio program was used to remove defects and inaccuracies of the obtained parametric model. A prototype of the finished model was made on the installation of laser stereolithography Projet 6000. Total time of the creation was 16 hours from the reverse engineering procedure to 3D-printing of the prototype.

  7. A systems engineering management approach to resource management applications

    Science.gov (United States)

    Hornstein, Rhoda Shaller

    1989-01-01

    The author presents a program management response to the following question: How can the traditional practice of systems engineering management, including requirements specification, be adapted, enhanced, or modified to build future planning and scheduling systems for effective operations? The systems engineering management process, as traditionally practiced, is examined. Extensible resource management systems are discussed. It is concluded that extensible systems are a partial solution to problems presented by requirements that are incomplete, partially immeasurable, and often dynamic. There are positive indications that resource management systems have been characterized and modeled sufficiently to allow their implementation as extensible systems.

  8. WAVELET-BASED ALGORITHM FOR DETECTION OF BEARING FAULTS IN A GAS TURBINE ENGINE

    Directory of Open Access Journals (Sweden)

    Sergiy Enchev

    2014-07-01

    Full Text Available Presented is a gas turbine engine bearing diagnostic system that integrates information from various advanced vibration analysis techniques to achieve robust bearing health state awareness. This paper presents a computational algorithm for identifying power frequency variations and integer harmonics by using wavelet-based transform. The continuous wavelet transform with  the complex Morlet wavelet is adopted to detect the harmonics presented in a power signal. The algorithm based on the discrete stationary wavelet transform is adopted to denoise the wavelet ridges.

  9. Multiplexed genome engineering and genotyping methods applications for synthetic biology and metabolic engineering.

    Science.gov (United States)

    Wang, Harris H; Church, George M

    2011-01-01

    Engineering at the scale of whole genomes requires fundamentally new molecular biology tools. Recent advances in recombineering using synthetic oligonucleotides enable the rapid generation of mutants at high efficiency and specificity and can be implemented at the genome scale. With these techniques, libraries of mutants can be generated, from which individuals with functionally useful phenotypes can be isolated. Furthermore, populations of cells can be evolved in situ by directed evolution using complex pools of oligonucleotides. Here, we discuss ways to utilize these multiplexed genome engineering methods, with special emphasis on experimental design and implementation. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. Microfabricated Chemical Sensors for Aerospace Fire Detection Applications

    Science.gov (United States)

    Hunter, Gary W.; Neudeck, Philip G.; Fralick, Gustave; Thomas, Valarie; Makel, D.; Liu, C. C.; Ward, B.; Wu, Q. H.

    2001-01-01

    The detection of fires on-board commercial aircraft is extremely important for safety reasons. Although dependable fire detection equipment presently exists within the cabin, detection of fire within the cargo hold has been less reliable and susceptible to false alarms. A second, independent method of fire detection to complement the conventional smoke detection techniques, such as the measurement of chemical species indicative of a fire, will help reduce false alarms and improve aircraft safety. Although many chemical species are indicative of a fire, two species of particular interest are CO and CO2. This paper discusses microfabricated chemical sensor development tailored to meet the needs of fire safety applications. This development is based on progress in three types of technology: 1) Micromachining and microfabrication (Microsystem) technology to fabricate miniaturized sensors. 2) The use of nanocrystalline materials to develop sensors with improved stability combined with higher sensitivity. 3) The development of high temperature semiconductors, especially silicon carbide. The individual sensor being developed and their level of maturity will be presented.

  11. [Application of lysosomal detection in marine pollution monitoring: research progress].

    Science.gov (United States)

    Weng, You-Zhu; Fang, Yong-Qiang; Zhang, Yu-Sheng

    2013-11-01

    Lysosome is an important organelle existing in eukaryotic cells. With the development of the study on the structure and function of lysosome in recent years, lysosome is considered as a target of toxic substances on subcellular level, and has been widely applied abroad in marine pollution monitoring. This paper summarized the biological characteristics of lysosomal marker enzyme, lysosome-autophagy system, and lysosomal membrane, and introduced the principles and methods of applying lysosomal detection in marine pollution monitoring. Bivalve shellfish digestive gland and fish liver are the most sensitive organs for lysosomal detection. By adopting the lysosomal detection techniques such as lysosomal membrane stability (LMS) test, neutral red retention time (NRRT) assay, morphological measurement (MM) of lysosome, immunohistochemical (Ih) assay of lysosomal marker enzyme, and electron microscopy (EM), the status of marine pollution can be evaluated. It was suggested that the lysosome could be used as a biomarker for monitoring marine environmental pollution. The advantages and disadvantages of lysosomal detection and some problems worthy of attention were analyzed, and the application prospects of lysosomal detection were discussed.

  12. Blueprint model and language for engineering cloud applications

    NARCIS (Netherlands)

    Nguyen, D.K.

    2013-01-01

    The research presented in this thesis is positioned within the domain of engineering CSBAs. Its contribution is twofold: (1) a uniform specification language, called the Blueprint Specification Language (BSL), for specifying cloud services across several cloud vendors and (2) a set of associated

  13. Application of neural networks in coastal engineering - An overview

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.; Patil, S.G.; Manjunatha, Y.R.; Hegde, A.V.

    Artificial Neural Network (ANN) is being applied to solve a wide variety of coastal/ocean engineering problems. In practical terms ANNs are non-linear modeling tools and they can be used to model complex relationship between the input and output...

  14. From biomedical-engineering research to clinical application and industrialization

    Science.gov (United States)

    Taguchi, Tetsushi; Aoyagi, Takao

    2012-12-01

    The rising costs and aging of the population due to a low birth rate negatively affect the healthcare system in Japan. In 2011, the Council for Science and Technology Policy released the 4th Japan's Science and Technology Basic Policy Report from 2011 to 2015. This report includes two major innovations, 'Life Innovation' and 'Green Innovation', to promote economic growth. Biomedical engineering research is part of 'Life Innovation' and its outcomes are required to maintain people's mental and physical health. It has already resulted in numerous biomedical products, and new ones should be developed using nanotechnology-based concepts. The combination of accumulated knowledge and experience, and 'nanoarchitechtonics' will result in novel, well-designed functional biomaterials. This focus issue contains three reviews and 19 original papers on various biomedical topics, including biomaterials, drug-delivery systems, tissue engineering and diagnostics. We hope that it demonstrates the importance of collaboration among scientists, engineers and clinicians, and will contribute to the further development of biomedical engineering.

  15. Systems Engineering Applications for Small Business Innovative Research (SBIR) Projects

    Science.gov (United States)

    2012-09-01

    Engineering processes within the SBIR community. Information was collected from multiple organizations throughout the SBIR community to support this research...Force by Program Executive Officers, Technolgy Directorates, Air Logistics Centers and Test Centers. SBIR projects are developed in three phases...found to be associated with SBIR projects and varied among organizations. Thus it became essential to conduct interviews to gather the information

  16. 40 CFR 94.221 - Application of good engineering judgment.

    Science.gov (United States)

    2010-07-01

    ... judgment in making all decisions called for under this part, including but not limited to selections... was not made in good faith, or that the decision was not made with a rational basis, the Administrator... Administrator may reject any such decision by a manufacturer if it is not based on good engineering judgment or...

  17. Nano-Science-Engineering-Technology Applications to Food and Nutrition.

    Science.gov (United States)

    Nakajima, Mitsutoshi; Wang, Zheng; Chaudhry, Qasim; Park, Hyun Jin; Juneja, Lekh R

    2015-01-01

    Nanoscale Science, Engineering and Technology are applied to Food and Nutrition. Various delivery systems include nanoemulsions, microemulsions, solid lipid nanoparticles, micelles, and liposomes. The nanoscale systems have advantages, such as higher bioavailabitity, and other physicochemical properties. The symposium will provide an overview of the formulation, characterization, and utilization of nanotechnology-based food and nutrition.

  18. Engineering light-matter interaction for emerging optical manipulation applications

    DEFF Research Database (Denmark)

    Qiu, Cheng-Wei; Palima, Darwin; Novitsky, Andrey

    2014-01-01

    In this review, we explore recent trends in optical micromanipulation by engineering light-matter interaction and controlling the mechanical effects of optical fields. One central theme is exploring the rich phenomena beyond the now established precision measurements based on trapping micro beads...

  19. A Dynamic Model for the Evaluation of Aircraft Engine Icing Detection and Control-Based Mitigation Strategies

    Science.gov (United States)

    Simon, Donald L.; Rinehart, Aidan W.; Jones, Scott M.

    2017-01-01

    Aircraft flying in regions of high ice crystal concentrations are susceptible to the buildup of ice within the compression system of their gas turbine engines. This ice buildup can restrict engine airflow and cause an uncommanded loss of thrust, also known as engine rollback, which poses a potential safety hazard. The aviation community is conducting research to understand this phenomena, and to identify avoidance and mitigation strategies to address the concern. To support this research, a dynamic turbofan engine model has been created to enable the development and evaluation of engine icing detection and control-based mitigation strategies. This model captures the dynamic engine response due to high ice water ingestion and the buildup of ice blockage in the engines low pressure compressor. It includes a fuel control system allowing engine closed-loop control effects during engine icing events to be emulated. The model also includes bleed air valve and horsepower extraction actuators that, when modulated, change overall engine operating performance. This system-level model has been developed and compared against test data acquired from an aircraft turbofan engine undergoing engine icing studies in an altitude test facility and also against outputs from the manufacturers customer deck. This paper will describe the model and show results of its dynamic response under open-loop and closed-loop control operating scenarios in the presence of ice blockage buildup compared against engine test cell data. Planned follow-on use of the model for the development and evaluation of icing detection and control-based mitigation strategies will also be discussed. The intent is to combine the model and control mitigation logic with an engine icing risk calculation tool capable of predicting the risk of engine icing based on current operating conditions. Upon detection of an operating region of risk for engine icing events, the control mitigation logic will seek to change the

  20. Application of integrated computer-aided engineering for design, construction and operation of nuclear power plant

    International Nuclear Information System (INIS)

    Kyung-shick Min; Byung-hun Lee

    1987-01-01

    Computer-aided-engineering (CAE) is an essential tool for modern nuclear power plant engineering. It greatly varies in definition, application, and technology from project to project and company to company. Despite the fast growing technologies and applications of CAE, its complexty and variety have thrown aonther puzzle to management of a nuclear project. Without due consideration of an integrated CAE system in early planning stage, the overall efficiency of a nuclear project would slow down due to the inefficiency in data flow. In this paper, practices and perspectives of CAE appliation are discussed under the Korea Power Engineering Company (KOPEC) philosophy in CAE approach. (author)