Sample records for engineering simulator applications

  1. Application of process simulators in chemical engineering process design -natural gas separation plant case study

    Directory of Open Access Journals (Sweden)

    Stevanović Dimitrije Ž.


    Full Text Available Software for chemical processes modeling and simulation, in the past few decades, play an important role in the development of chemical-process industry with their growing capabilities and wide range of application. Usage of process simulators in Serbia for the process design is very limited. This paper gives a brief overview of the numerous process simulators that are used in the chemical-process industry today. The conceptual design is responsible for most of the investment costs in chemical process industry. Importance of precise design on preliminary level is obvious. Wrong decisions made at the conceptual level could be carried out throughout the chain in process design to the detailed design procedures and procurement of equipment. Although preliminary design phase comprises only about 2% of the total cost of the project, it contributes significantly to the reduction of cost of the project by more than 30%. Therefore process simulators play important role in elimination of unnecessary errors in basic process design. Here is also shown a case study of parallel process simulated in different process simulators which tests the results, the reliability and usefulness of these programs in solving specific engineering tasks. Comparison of given simulation results confirm that the modern process simulators are at high level of confidence, no matter they are based on different models, equations, methods, operations, interfaces or data bases. Usage of software speeds up the arrival of optimized solution during the design and the operational procedures. Therefore software have significant impact on reducing time of pre-project phase such as research, conceptual design, and proving project abilities. It’s development lead to faster commercialization of industrial ideas. [Projekat Ministartsva nauke Republike Srbije, br. TR 34009

  2. DEM GPU studies of industrial scale particle simulations for granular flow civil engineering applications (United States)

    Pizette, Patrick; Govender, Nicolin; Wilke, Daniel N.; Abriak, Nor-Edine


    The use of the Discrete Element Method (DEM) for industrial civil engineering industrial applications is currently limited due to the computational demands when large numbers of particles are considered. The graphics processing unit (GPU) with its highly parallelized hardware architecture shows potential to enable solution of civil engineering problems using discrete granular approaches. We demonstrate in this study the pratical utility of a validated GPU-enabled DEM modeling environment to simulate industrial scale granular problems. As illustration, the flow discharge of storage silos using 8 and 17 million particles is considered. DEM simulations have been performed to investigate the influence of particle size (equivalent size for the 20/40-mesh gravel) and induced shear stress for two hopper shapes. The preliminary results indicate that the shape of the hopper significantly influences the discharge rates for the same material. Specifically, this work shows that GPU-enabled DEM modeling environments can model industrial scale problems on a single portable computer within a day for 30 seconds of process time.

  3. LAMMPS integrated materials engine (LIME) for efficient automation of particle-based simulations: application to equation of state generation (United States)

    Barnes, Brian C.; Leiter, Kenneth W.; Becker, Richard; Knap, Jaroslaw; Brennan, John K.


    We describe the development, accuracy, and efficiency of an automation package for molecular simulation, the large-scale atomic/molecular massively parallel simulator (LAMMPS) integrated materials engine (LIME). Heuristics and algorithms employed for equation of state (EOS) calculation using a particle-based model of a molecular crystal, hexahydro-1,3,5-trinitro-s-triazine (RDX), are described in detail. The simulation method for the particle-based model is energy-conserving dissipative particle dynamics, but the techniques used in LIME are generally applicable to molecular dynamics simulations with a variety of particle-based models. The newly created tool set is tested through use of its EOS data in plate impact and Taylor anvil impact continuum simulations of solid RDX. The coarse-grain model results from LIME provide an approach to bridge the scales from atomistic simulations to continuum simulations.

  4. Engineering dynamics from the Lagrangian to simulation

    CERN Document Server

    Gans, Roger F


    This engineering dynamics textbook is aimed at beginning graduate students in mechanical engineering and other related engineering disciplines who need training in dynamics as applied to engineering mechanisms. It introduces the formal mathematical development of Lagrangian mechanics (and its corollaries), while solving numerous engineering applications. The author’s goal is to instill an understanding of the basic physics required for engineering dynamics, while providing a recipe (algorithm) for the simulation of engineering mechanisms such as robots. The book is reasonably self-contained so that the practicing engineer interested in this area can also make use of it. This book is made accessible to the widest possible audience by numerous, solved examples and diagrams that apply the principles to real engineering applications. • Provides an applied textbook for intermediate/advanced engineering dynamics courses; • Discusses Lagrangian mechanics in the context of numerous engineering applications...

  5. Simulation of ODE/PDE models with MATLAB, OCTAVE and SCILAB scientific and engineering applications

    CERN Document Server

    Vande Wouwer, Alain; Vilas, Carlos


    Simulation of ODE/PDE Models with MATLAB®, OCTAVE and SCILAB shows the reader how to exploit a fuller array of numerical methods for the analysis of complex scientific and engineering systems than is conventionally employed. The book is dedicated to numerical simulation of distributed parameter systems described by mixed systems of algebraic equations, ordinary differential equations (ODEs) and partial differential equations (PDEs). Special attention is paid to the numerical method of lines (MOL), a popular approach to the solution of time-dependent PDEs, which proceeds in two basic steps: spatial discretization and time integration. Besides conventional finite-difference and -element techniques, more advanced spatial-approximation methods are examined in some detail, including nonoscillatory schemes and adaptive-grid approaches. A MOL toolbox has been developed within MATLAB®/OCTAVE/SCILAB. In addition to a set of spatial approximations and time integrators, this toolbox includes a collection of applicatio...

  6. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming Analysis, Simulation and Engineering Applications

    CERN Document Server

    Hu, Ping; Liu, Li-zhong; Zhu, Yi-guo


    Over the last 15 years, the application of innovative steel concepts in the automotive industry has increased steadily. Numerical simulation technology of hot forming of high-strength steel allows engineers to modify the formability of hot forming steel metals and to optimize die design schemes. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming focuses on hot and cold forming theories, numerical methods, relative simulation and experiment techniques for high-strength steel forming and die design in the automobile industry. Theories, Methods and Numerical Technology of Sheet Metal Cold and Hot Forming introduces the general theories of cold forming, then expands upon advanced hot forming theories and simulation methods, including: • the forming process, • constitutive equations, • hot boundary constraint treatment, and • hot forming equipment and experiments. Various calculation methods of cold and hot forming, based on the authors’ experience in commercial CAE software f...

  7. An Introduction to Transient Engine Applications Using the Numerical Propulsion System Simulation (NPSS) and MATLAB (United States)

    Chin, Jeffrey C.; Csank, Jeffrey T.; Haller, William J.; Seidel, Jonathan A.


    This document outlines methodologies designed to improve the interface between the Numerical Propulsion System Simulation framework and various control and dynamic analyses developed in the Matlab and Simulink environment. Although NPSS is most commonly used for steady-state modeling, this paper is intended to supplement the relatively sparse documentation on it's transient analysis functionality. Matlab has become an extremely popular engineering environment, and better methodologies are necessary to develop tools that leverage the benefits of these disparate frameworks. Transient analysis is not a new feature of the Numerical Propulsion System Simulation (NPSS), but transient considerations are becoming more pertinent as multidisciplinary trade-offs begin to play a larger role in advanced engine designs. This paper serves to supplement the relatively sparse documentation on transient modeling and cover the budding convergence between NPSS and Matlab based modeling toolsets. The following sections explore various design patterns to rapidly develop transient models. Each approach starts with a base model built with NPSS, and assumes the reader already has a basic understanding of how to construct a steady-state model. The second half of the paper focuses on further enhancements required to subsequently interface NPSS with Matlab codes. The first method being the simplest and most straightforward but performance constrained, and the last being the most abstract. These methods aren't mutually exclusive and the specific implementation details could vary greatly based on the designer's discretion. Basic recommendations are provided to organize model logic in a format most easily amenable to integration with existing Matlab control toolsets.

  8. Pneumatic pulsator design as an example of numerical simulations in engineering applications (United States)

    Wołosz, Krzysztof; Wernik, Jacek


    The paper presents the part of the investigation that has been carried out in order to develop the pneumatic pulsator which is to be employed as an unblocking device at lose material silo outlets. The part of numerical simulation is reported. The fluid dynamics issues have been outlined which are present during supersonic airflow thought the head of the pulsator. These issues describe the pneumatic impact phenomenon onto the loose material bed present in the silo to which walls the pulsator is assembled. The investigation presented in the paper are industrial applicable and the result is the working prototype of the industrial pneumatic pulsator. The numerical simulation has led to change the piston shape which is moving inside the head of the pulsator, and therefore, to reduce the pressure losses during the airflow. A stress analysis of the pulsator controller body has been carried out while the numerical simulation investigation part of the whole project. The analysis has made possible the change of the controller body material from cast iron to aluminium alloy.

  9. Vortex Characterization for Engineering Applications

    Energy Technology Data Exchange (ETDEWEB)

    Jankun-Kelly, M; Thompson, D S; Jiang, M; Shannahan, B; Machiraju, R


    Realistic engineering simulation data often have features that are not optimally resolved due to practical limitations on mesh resolution. To be useful to application engineers, vortex characterization techniques must be sufficiently robust to handle realistic data with complex vortex topologies. In this paper, we present enhancements to the vortex topology identification component of an existing vortex characterization algorithm. The modified techniques are demonstrated by application to three realistic data sets that illustrate the strengths and weaknesses of our approach.

  10. An architecture and model for cognitive engineering simulation analysis - Application to advanced aviation automation (United States)

    Corker, Kevin M.; Smith, Barry R.


    The process of designing crew stations for large-scale, complex automated systems is made difficult because of the flexibility of roles that the crew can assume, and by the rapid rate at which system designs become fixed. Modern cockpit automation frequently involves multiple layers of control and display technology in which human operators must exercise equipment in augmented, supervisory, and fully automated control modes. In this context, we maintain that effective human-centered design is dependent on adequate models of human/system performance in which representations of the equipment, the human operator(s), and the mission tasks are available to designers for manipulation and modification. The joint Army-NASA Aircrew/Aircraft Integration (A3I) Program, with its attendant Man-machine Integration Design and Analysis System (MIDAS), was initiated to meet this challenge. MIDAS provides designers with a test bed for analyzing human-system integration in an environment in which both cognitive human function and 'intelligent' machine function are described in similar terms. This distributed object-oriented simulation system, its architecture and assumptions, and our experiences from its application in advanced aviation crew stations are described.

  11. Systems Engineering Simulator (SES) Simulator Planning Guide (United States)

    McFarlane, Michael


    The simulation process, milestones and inputs are unknowns to first-time users of the SES. The Simulator Planning Guide aids in establishing expectations for both NASA and non-NASA facility customers. The potential audience for this guide includes both internal and commercial spaceflight hardware/software developers. It is intended to assist their engineering personnel in simulation planning and execution. Material covered includes a roadmap of the simulation process, roles and responsibilities of facility and user, major milestones, facility capabilities, and inputs required by the facility. Samples of deliverables, facility interfaces, and inputs necessary to define scope, cost, and schedule are included as an appendix to the guide.

  12. Design and simulation of oxide and doping engineered lateral bipolar junction transistors for high power applications (United States)

    Loan, Sajad A.; Bashir, Faisal; Akhoon, M. Saqib; Alamoud, Abdulrahman M.


    In this paper, we propose new structures of lateral bipolar junction transistor (LBJT) on silicon on insulator (SOI) with improved performance. The proposed devices are lateral bipolar transistors with multi doping zone collector drift region and a thick buried oxide under the collector region. Calibrated simulation studies have revealed that the proposed devices have higher breakdown voltage than the conventional device, that too at higher drift doping concentration. This has resulted in improved tradeoff between the on-resistance and the breakdown voltage of the proposed devices. It has been observed that the proposed device with two collector drift doping zones and a buried oxide thick step results in ∼190% increase in the breakdown voltage than the conventional device. The further increase in the number of collector drift doping zones from two to three has increased the breakdown voltage by 260% than the conventional one. On comparing the proposed devices with the buried oxide double step devices, it has been found that an increase of ∼15-19% in the breakdown voltage is observed in the proposed devices even at higher drift doping concentrations. The use of higher drift doping concentration reduces the on-resistance of the proposed device and thus improves the tradeoff between the breakdown voltage and the on-resistance of the proposed device in comparison to buried oxide double step devices. Further, the use of step doping in the collector drift region has resulted in the reduction of kink effect in the proposed device. Using the mixed mode simulations, the proposed devices have been tested at the circuit level, by designing and simulating inverting amplifiers employing the proposed devices. Both DC and AC analyses of the inverting amplifiers have shown that the proposed devices work well at the circuit level. It has been observed that there is a slight increase in ON delay in the proposed device; however, the OFF delay is more or less same as that of the

  13. Engineering Web Applications

    DEFF Research Database (Denmark)

    Casteleyn, Sven; Daniel, Florian; Dolog, Peter

    Nowadays, Web applications are almost omnipresent. The Web has become a platform not only for information delivery, but also for eCommerce systems, social networks, mobile services, and distributed learning environments. Engineering Web applications involves many intrinsic challenges due...... to their distributed nature, content orientation, and the requirement to make them available to a wide spectrum of users who are unknown in advance. The authors discuss these challenges in the context of well-established engineering processes, covering the whole product lifecycle from requirements engineering through...

  14. Information Engineering and Applications

    CERN Document Server

    Ma, Yan; International Conference on Information Engineering and Applications (IEA) 2011


    The International Conference on Information Engineering and Applications (IEA) 2011 will be held on October 21-24, 2011, in Chongqing, China. It is organized by Chongqing Normal University, Chongqing University, Shanghai Jiao Tong University, Nanyang Technological University, the University of Michigan, Chongqing University of Arts and Sciences, and sponsored by the National Natural Science Foundation of China. The objective of IEA 2011 is to facilitate an exchange of information on best practices for the latest research advances in the area of information engineering and intelligence applications, which mainly includes computer science and engineering, informatics, communications and control, electrical engineering, information computing, business intelligence and management. IEA 2011 will provide a forum for engineers and scientists in academia, industry, and government to address the most innovative research and development including technical challenges, social and economic issues, and to present and disc...

  15. Application for managing model-based material properties for simulation-based engineering (United States)

    Hoffman, Edward L [Alameda, CA


    An application for generating a property set associated with a constitutive model of a material includes a first program module adapted to receive test data associated with the material and to extract loading conditions from the test data. A material model driver is adapted to receive the loading conditions and a property set and operable in response to the loading conditions and the property set to generate a model response for the material. A numerical optimization module is adapted to receive the test data and the model response and operable in response to the test data and the model response to generate the property set.

  16. Engineering Adaptive Applications

    DEFF Research Database (Denmark)

    Dolog, Peter

    for a domain.In this book, we propose a new domain engineering framework which extends a development process of Web applications with techniques required when designing such adaptive customizable Web applications. The framework is provided with design abstractions which deal separately with information served...

  17. Rocket Engine Altitude Simulation Technologies (United States)

    Woods, Jody L.; Lansaw, John


    John C. Stennis Space Center is embarking on a very ambitious era in its rocket engine propulsion test history. The first new large rocket engine test stand to be built at Stennis Space Center in over 40 years is under construction. The new A3 Test Stand is designed to test very large (294,000 Ibf thrust) cryogenic propellant rocket engines at a simulated altitude of 100,000 feet. A3 Test Stand will have an engine testing chamber where the engine will be fired after the air in the chamber has been evacuated to a pressure at the simulated altitude of less than 0.16 PSIA. This will result in a very unique environment with extremely low pressures inside a very large chamber and ambient pressures outside this chamber. The test chamber is evacuated of air using a 2-stage diffuser / ejector system powered by 5000 lb/sec of steam produced by 27 chemical steam generators. This large amount of power and flow during an engine test will result in a significant acoustic and vibrational environment in and around A3 Test Stand.

  18. Developing an Internet Oriented Platform for Earthquake Engineering Application and Web-based Virtual Reality Simulation System for Seismic hazards: Towards Disaster Mitigation in Metropolises

    Directory of Open Access Journals (Sweden)

    Ali Alaghehbandian


    Full Text Available This paper reviews the state of the art on risk communication to the public, with an emphasis on simulation of seismic hazards using VRML. Rapid growth computer technologies, especially the Internet provide human beings new measures to deal with engineering and social problems which were hard to solve in traditional ways. This paper presents a prototype of an application platform based on the Internet using VR (Virtual Reality for civil engineering considering building an information system of risk communication for seismic hazards and at the moment in the case of bridge structure.

  19. Otto engine simulation in Dymola

    Energy Technology Data Exchange (ETDEWEB)

    Egnell, R.


    A component library for otto engines has been developed in Dymola and three otto engines have been built using these components. This work has been part of a bigger project of which the goal is to develop the structure of a vehicle simulation program package and, in the process, evaluate different commercially available simulation tools. In order to develop the vehicle simulation package models of the various subsystems and components must be available to define the interface between them. The Otto engine models developed for this purpose are based on steady state measurements of performance and emissions. The steady state input is however corrected with respect to the actual transient conditions. In order to achieve this a lot of attention has been paid to the factors influencing the lambda excursions. Three main factors have been identified. They are: 1. Bad synchronization between the air and the fuel flow entering the engine., 2. Fuel wetting of the inlet port walls., 3. The delay time in the lambda control feed back loop

  20. Complex systems models: engineering simulations


    Polack, Fiona A. C.; Hoverd, Tim; Sampson, Adam T.; Stepney, Susan; Timmis, Jon,


    As part of research towards the CoSMoS unified infrastructure for modelling and simulating complex systems, we review uses of definitional and descriptive models in natural science and computing, and existing integrated platforms. From these, we identify requirements for engineering models of complex systems, and consider how some of the requirements could be met, using state-of-the-art model management and a mobile, process-oriented computing paradigm.

  1. Applications of Computer Graphics in Engineering (United States)


    Various applications of interactive computer graphics to the following areas of science and engineering were described: design and analysis of structures, configuration geometry, animation, flutter analysis, design and manufacturing, aircraft design and integration, wind tunnel data analysis, architecture and construction, flight simulation, hydrodynamics, curve and surface fitting, gas turbine engine design, analysis, and manufacturing, packaging of printed circuit boards, spacecraft design.

  2. BEST: Biochemical Engineering Simulation Technology

    Energy Technology Data Exchange (ETDEWEB)


    The idea of developing a process simulator that can describe biochemical engineering (a relatively new technology area) was formulated at the National Renewable Energy Laboratory (NREL) during the late 1980s. The initial plan was to build a consortium of industrial and U.S. Department of Energy (DOE) partners to enhance a commercial simulator with biochemical unit operations. DOE supported this effort; however, before the consortium was established, the process simulator industry changed considerably. Work on the first phase of implementing various fermentation reactors into the chemical process simulator, ASPEN/SP-BEST, is complete. This report will focus on those developments. Simulation Sciences, Inc. (SimSci) no longer supports ASPEN/SP, and Aspen Technology, Inc. (AspenTech) has developed an add-on to its ASPEN PLUS (also called BioProcess Simulator [BPS]). This report will also explain the similarities and differences between BEST and BPS. ASPEN, developed by the Massachusetts Institute of Technology for DOE in the late 1970s, is still the state-of-the-art chemical process simulator. It was selected as the only simulator with the potential to be easily expanded into the biochemical area. ASPEN/SP, commercially sold by SimSci, was selected for the BEST work. SimSci completed work on batch, fed-batch, and continuous fermentation reactors in 1993, just as it announced it would no longer commercially support the complete ASPEN/SP product. BEST was left without a basic support program. Luckily, during this same time frame, AspenTech was developing a biochemical simulator with its version of ASPEN (ASPEN PLUS), which incorporates most BEST concepts. The future of BEST will involve developing physical property data and models appropriate to biochemical systems that are necessary for good biochemical process design.

  3. A computer simulator for development of engineering system design methodologies (United States)

    Padula, S. L.; Sobieszczanski-Sobieski, J.


    A computer program designed to simulate and improve engineering system design methodology is described. The simulator mimics the qualitative behavior and data couplings occurring among the subsystems of a complex engineering system. It eliminates the engineering analyses in the subsystems by replacing them with judiciously chosen analytical functions. With the cost of analysis eliminated, the simulator is used for experimentation with a large variety of candidate algorithms for multilevel design optimization to choose the best ones for the actual application. Thus, the simulator serves as a development tool for multilevel design optimization strategy. The simulator concept, implementation, and status are described and illustrated with examples.

  4. Engineering Adaptive Web Applications

    DEFF Research Database (Denmark)

    Dolog, Peter


    Information and services on the web are accessible for everyone. Users of the web differ in their background, culture, political and social environment, interests and so on. Ambient intelligence was envisioned as a concept for systems which are able to adapt to user actions and needs. With the gr......Information and services on the web are accessible for everyone. Users of the web differ in their background, culture, political and social environment, interests and so on. Ambient intelligence was envisioned as a concept for systems which are able to adapt to user actions and needs...... suit the user profile the most. This paper summarizes the domain engineering framework for such adaptive web applications. The framework provides guidelines to develop adaptive web applications as members of a family. It suggests how to utilize the design artifacts as knowledge which can be used...

  5. Dynamics simulations for engineering macromolecular interactions (United States)

    Robinson-Mosher, Avi; Shinar, Tamar; Silver, Pamela A.; Way, Jeffrey


    The predictable engineering of well-behaved transcriptional circuits is a central goal of synthetic biology. The artificial attachment of promoters to transcription factor genes usually results in noisy or chaotic behaviors, and such systems are unlikely to be useful in practical applications. Natural transcriptional regulation relies extensively on protein-protein interactions to insure tightly controlled behavior, but such tight control has been elusive in engineered systems. To help engineer protein-protein interactions, we have developed a molecular dynamics simulation framework that simplifies features of proteins moving by constrained Brownian motion, with the goal of performing long simulations. The behavior of a simulated protein system is determined by summation of forces that include a Brownian force, a drag force, excluded volume constraints, relative position constraints, and binding constraints that relate to experimentally determined on-rates and off-rates for chosen protein elements in a system. Proteins are abstracted as spheres. Binding surfaces are defined radially within a protein. Peptide linkers are abstracted as small protein-like spheres with rigid connections. To address whether our framework could generate useful predictions, we simulated the behavior of an engineered fusion protein consisting of two 20 000 Da proteins attached by flexible glycine/serine-type linkers. The two protein elements remained closely associated, as if constrained by a random walk in three dimensions of the peptide linker, as opposed to showing a distribution of distances expected if movement were dominated by Brownian motion of the protein domains only. We also simulated the behavior of fluorescent proteins tethered by a linker of varying length, compared the predicted Förster resonance energy transfer with previous experimental observations, and obtained a good correspondence. Finally, we simulated the binding behavior of a fusion of two ligands that could

  6. VCSEL Applications and Simulation (United States)

    Cheung, Samson; Goorjian, Peter; Ning, Cun-Zheng; Li, Jian-Zhong


    This viewgraph presentation gives an overview of Vertical Cavity Surface Emitting Laser (VCSEL) simulation and its applications. Details are given on the optical interconnection in information technology of VCSEL, the formulation of the simulation, its numeric algorithm, and the computational results.

  7. High-Fidelity Simulation and Analysis of Ignition Regimes and Mixing Characteristics for Low Temperature Combustion Engine Application (United States)

    Gupta, Saurabh

    Computational singular perturbation (CSP) technique is applied as an automated diagnostic tool to classify ignition regimes, especially spontaneous ignition front and deflagration in low temperature combustion (LTC) engine environments. Various model problems representing LTC are simulated using high-fidelity computation with detailed chemistry for hydrogen-air, and the simulation data are then analyzed by CSP. The active reaction zones are first identified by the locus of minimum number of fast exhausted time scales. Subsequently, the relative importance of transport and chemistry is determined in the region ahead of the reaction zone. A new index IT, defined as the sum of the absolute values of the importance indices of diffusion and convection of temperature to the slow dynamics of temperature, serves as a criterion to differentiate spontaneous ignition from deflagration regimes. The same strategy is then used to gain insights into classification of ignition regimes in n-heptane air mixtures. Parametric studies are conducted using high-fidelity simulations with detailed chemistry and transport. The mixture at non-NTC conditions shows initially a deflagration front which is subsequently transitioned into a spontaneous ignition front. For the mixtures at the NTC conditions which exhibit two-stage ignition behavior, the 1 st stage ignition front is found to be more likely in the deflagration regime. On the other hand, the 2nd stage ignition front occurs almost always in the spontaneous regime because the upstream mixture contains active radical species produced by the preceding 1st stage ignition front. The effects of differently correlated equivalence ratio stratification are also considered and the results are shown to be consistent with previous findings. 2D turbulent auto-ignition problems corresponding to NTC and non-NTC chemistry yield similar qualitative results. Finally, we look into the modeling of turbulent mixing, in particular, the scalar dissipation

  8. Industrial applications of affective engineering

    CERN Document Server

    Shiizuka, Hisao; Lee, Kun-Pyo; Otani, Tsuyoshi; Lim, Chee-Peng


    This book examines the industrial applications of affective engineering. The contributors cover new analytical methods such as fluctuation, fuzzy logic, fractals, and complex systems. These chapters also include interdisciplinary research that traverses a wide range of fields, including information engineering, human engineering, cognitive science, psychology, and design studies. The text is split into two parts: theory and applications. This work is a collection of the best papers from ISAE2013 (International Symposium of Affective Engineering) held at Kitakyushu, Japan and Japan Kansei Engineering Meeting on March 6-8, 2013.

  9. Engine Modelling for Control Applications

    DEFF Research Database (Denmark)

    Hendricks, Elbert


    In earlier work published by the author and co-authors, a dynamic engine model called a Mean Value Engine Model (MVEM) was developed. This model is physically based and is intended mainly for control applications. In its newer form, it is easy to fit to many different engines and requires little...... engine data for this purpose. It is especially well suited to embedded model applications in engine controllers, such as nonlinear observer based air/fuel ratio and advanced idle speed control. After a brief review of this model, it will be compared with other similar models which can be found...

  10. Distributed simulation a model driven engineering approach

    CERN Document Server

    Topçu, Okan; Oğuztüzün, Halit; Yilmaz, Levent


    Backed by substantive case studies, the novel approach to software engineering for distributed simulation outlined in this text demonstrates the potent synergies between model-driven techniques, simulation, intelligent agents, and computer systems development.

  11. Simulation based engineering in solid mechanics

    CERN Document Server

    Rao, J S


    This book begins with a brief historical perspective of the advent of rotating machinery in 20th century Solid Mechanics and the development of the discipline of the Strength of Materials. High Performance Computing (HPC) and Simulation Based Engineering Science (SBES) have gradually replaced the conventional approach in Design bringing science directly into engineering without approximations. A recap of the required mathematical principles is given. The science of deformation, strain and stress at a point under the application of external traction loads is next presented. Only one-dimensional structures classified as Bars (axial loads), Rods (twisting loads) and Beams (bending loads) are considered in this book. The principal stresses and strains and von Mises stress and strain that used in design of structures are next presented. Lagrangian solution was used to derive the governing differential equations consistent with assumed deformation field and solution for deformations, strains and stresses were obtai...

  12. Multiphysics simulation electromechanical system applications and optimization

    CERN Document Server

    Dede, Ercan M; Nomura, Tsuyoshi


    This book highlights a unique combination of numerical tools and strategies for handling the challenges of multiphysics simulation, with a specific focus on electromechanical systems as the target application. Features: introduces the concept of design via simulation, along with the role of multiphysics simulation in today's engineering environment; discusses the importance of structural optimization techniques in the design and development of electromechanical systems; provides an overview of the physics commonly involved with electromechanical systems for applications such as electronics, ma

  13. Engineering uses of physics-based ground motion simulations (United States)

    Baker, Jack W.; Luco, Nicolas; Abrahamson, Norman A.; Graves, Robert W.; Maechling, Phillip J.; Olsen, Kim B.


    This paper summarizes validation methodologies focused on enabling ground motion simulations to be used with confidence in engineering applications such as seismic hazard analysis and dynmaic analysis of structural and geotechnical systems. Numberical simullation of ground motion from large erthquakes, utilizing physics-based models of earthquake rupture and wave propagation, is an area of active research in the earth science community. Refinement and validatoin of these models require collaboration between earthquake scientists and engineering users, and testing/rating methodolgies for simulated ground motions to be used with confidence in engineering applications. This paper provides an introduction to this field and an overview of current research activities being coordinated by the Souther California Earthquake Center (SCEC). These activities are related both to advancing the science and computational infrastructure needed to produce ground motion simulations, as well as to engineering validation procedures. Current research areas and anticipated future achievements are also discussed.

  14. application to engine systems

    Directory of Open Access Journals (Sweden)

    G. George Zhu


    Full Text Available The q-Markov COVariance Equivalent Realization (q-Markov Cover method for identification uses either pulse, white noise or PRBS (Pseudo-Random Binary Signal as test excitation. This paper extended the q-Markov Cover using PRBS to the weighted multirate case, that is, the sample rate of the PRBS signal is different from the system output one. Then, the multirate PRBS q-Markov Cover is applied to identify a diesel engine model from the fuel command input to the engine speed output. The identified engine model has order of two and approximates the pure fuel system time delay using a first-order transfer function with a non-minimum phase numerator. Finally, the identified engine model was successfully used for designing engine idle speed governor and obtained satisfactory performance in the first try.

  15. Optimization strategies for complex engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Eldred, M.S.


    LDRD research activities have focused on increasing the robustness and efficiency of optimization studies for computationally complex engineering problems. Engineering applications can be characterized by extreme computational expense, lack of gradient information, discrete parameters, non-converging simulations, and nonsmooth, multimodal, and discontinuous response variations. Guided by these challenges, the LDRD research activities have developed application-specific techniques, fundamental optimization algorithms, multilevel hybrid and sequential approximate optimization strategies, parallel processing approaches, and automatic differentiation and adjoint augmentation methods. This report surveys these activities and summarizes the key findings and recommendations.

  16. Simulations, serious games and their applications

    CERN Document Server

    Goei, Sui


    This book presents the state of the art technology in Serious Games which is driven extensive by applications and research in simulation. The topics in this book include: (1) Fashion simulation; (2) Chinese calligraphy ink diffusion simulation; (3) Rehabilitation (4) Long vehicle turning simulation; (5) Marine traffic conflict control; (6) CNC simulation; (7) Special needs education. The book also addresses the fundamental issues in Simulation and Serious Games such as rapid collision detection, game engines or game development platforms. The target audience for this book includes scientists, engineers and practitioners involved in the field of Serious Games and Simulation. The major part of this book comprises of papers presented at the 2012 Asia-Europe Workshop on Serious Games and Simulation held in Nanyang Technological University, Singapore (May 9, 2012).  All the contributions have been peer reviewed and by scientific committee members with report about quality, content and originality.

  17. WDM Systems and Networks Modeling, Simulation, Design and Engineering

    CERN Document Server

    Ellinas, Georgios; Roudas, Ioannis


    WDM Systems and Networks: Modeling, Simulation, Design and Engineering provides readers with the basic skills, concepts, and design techniques used to begin design and engineering of optical communication systems and networks at various layers. The latest semi-analytical system simulation techniques are applied to optical WDM systems and networks, and a review of the various current areas of optical communications is presented. Simulation is mixed with experimental verification and engineering to present the industry as well as state-of-the-art research. This contributed volume is divided into three parts, accommodating different readers interested in various types of networks and applications. The first part of the book presents modeling approaches and simulation tools mainly for the physical layer including transmission effects, devices, subsystems, and systems), whereas the second part features more engineering/design issues for various types of optical systems including ULH, access, and in-building system...

  18. Nonlinear Approaches in Engineering Applications

    CERN Document Server

    Jazar, Reza


    Nonlinear Approaches in Engineering Applications focuses on nonlinear phenomena that are common in the engineering field. The nonlinear approaches described in this book provide a sound theoretical base and practical tools to design and analyze engineering systems with high efficiency and accuracy and with less energy and downtime. Presented here are nonlinear approaches in areas such as dynamic systems, optimal control and approaches in nonlinear dynamics and acoustics. Coverage encompasses a wide range of applications and fields including mathematical modeling and nonlinear behavior as applied to microresonators, nanotechnologies, nonlinear behavior in soil erosion,nonlinear population dynamics, and optimization in reducing vibration and noise as well as vibration in triple-walled carbon nanotubes. This book also: Provides a complete introduction to nonlinear behavior of systems and the advantages of nonlinearity as a tool for solving engineering problems Includes applications and examples drawn from the el...

  19. Engineering applications of soft computing

    CERN Document Server

    Díaz-Cortés, Margarita-Arimatea; Rojas, Raúl


    This book bridges the gap between Soft Computing techniques and their applications to complex engineering problems. In each chapter we endeavor to explain the basic ideas behind the proposed applications in an accessible format for readers who may not possess a background in some of the fields. Therefore, engineers or practitioners who are not familiar with Soft Computing methods will appreciate that the techniques discussed go beyond simple theoretical tools, since they have been adapted to solve significant problems that commonly arise in such areas. At the same time, the book will show members of the Soft Computing community how engineering problems are now being solved and handled with the help of intelligent approaches. Highlighting new applications and implementations of Soft Computing approaches in various engineering contexts, the book is divided into 12 chapters. Further, it has been structured so that each chapter can be read independently of the others.

  20. Simulation and Spacecraft Design: Engineering Mars Landings. (United States)

    Conway, Erik M


    A key issue in history of technology that has received little attention is the use of simulation in engineering design. This article explores the use of both mechanical and numerical simulation in the design of the Mars atmospheric entry phases of the Viking and Mars Pathfinder missions to argue that engineers used both kinds of simulation to develop knowledge of their designs' likely behavior in the poorly known environment of Mars. Each kind of simulation could be used as a warrant of the other's fidelity, in an iterative process of knowledge construction.

  1. Computer Simulation in Information and Communication Engineering

    CERN Multimedia

    Anton Topurov


    CSICE'05 Sofia, Bulgaria 20th - 22nd October, 2005 On behalf of the International Scientific Committee, we would like to invite you all to Sofia, the capital city of Bulgaria, to the International Conference in Computer Simulation in Information and Communication Engineering CSICE'05. The Conference is aimed at facilitating the exchange of experience in the field of computer simulation gained not only in traditional fields (Communications, Electronics, Physics...) but also in the areas of biomedical engineering, environment, industrial design, etc. The objective of the Conference is to bring together lectures, researchers and practitioners from different countries, working in the fields of computer simulation in information engineering, in order to exchange information and bring new contribution to this important field of engineering design and education. The Conference will bring you the latest ideas and development of the tools for computer simulation directly from their inventors. Contribution describ...


    Bisdorf, Robert J.


    Surface electrical geophysical methods have been used in such engineering applications as locating and delineating shallow gravel deposits, depth to bedrock, faults, clay zones, and other geological phenomena. Other engineering applications include determining water quality, tracing ground water contaminant plumes and locating dam seepages. Various methods and electrode arrays are employed to solve particular geological problems. The sensitivity of a particular method or electrode array depends upon the physics on which the method is based, the array geometry, the electrical contrast between the target and host materials, and the depth to the target. Each of the available electrical methods has its own particular advantages and applications which the paper discusses.

  3. Simulation Application for the LHCb Experiment

    CERN Document Server

    Pokorski, Witold


    We describe the LHCb detector simulation application (Gauss) based on the Geant4 toolkit. The application is built using the Gaudi software framework, which is used for all event-processing applications in the LHCb experiment. The existence of an underlying framework allows several common basic services such as persistency, interactivity, as well as detector geometry description or particle data to be shared between simulation, reconstruction and analysis applications. The main benefits of such common services are coherence between different event-processing stages as well as reduced development effort. The interfacing to Geant4 toolkit is realized through a façade (GiGa) which minimizes the coupling to the simulation engine and provides a set of abstract interfaces for configuration and event-by-event communication. The Gauss application is composed of three main blocks, i.e. event generation, detector response simulation and digitization which reflect the different stages performed during the simulation jo...

  4. Study of the rheological properties of water and Martian soil simulant mixtures for engineering applications on the red planet (United States)

    Taylor, Lewis; Alberini, Federico; Sullo, Antonio; Meyer, Marit E.; Alexiadis, Alessio


    The rheological properties of mixtures of water and the Martian soil simulant JSC-Mars-1A are investigated by preparing and testing samples at various solids concentrations. The results indicate that the dispersion is viscoelastic and, at small timescales (∼0.1 s), reacts to sudden strain as an elastic solid. At longer timescales the dispersion behaves like a Bingham fluid and exhibits a yield stress. Hysteresis loops show that rapid step-changes (2 s duration) of shear-rate result in thixotropic behaviour, but slower changes (>10 s duration) can result in rheopexy. These observations are explained with the breakdown and recovery of the packing structure under stress. The rheological information is used to generate practical tools, such as the system curve and the Moody chart that can be used for designing piping systems, and calculating pump sizes and pressure requirements.

  5. Cognitive engineering in aerospace applications (United States)

    Woods, David D.


    The progress that was made with respect to the objectives and goals of the research that is being carried out in the Cognitive Systems Engineering Laboratory (CSEL) under a Cooperative Agreement with NASA Ames Research Center is described. The major objective of this project is to expand the research base in Cognitive Engineering to be able to support the development and human-centered design of automated systems for aerospace applications. This research project is in support of the Aviation Safety/Automation Research plan and related NASA research goals in space applications.

  6. Analysis and simulation of Wiseman hypocycloid engine

    Directory of Open Access Journals (Sweden)

    Priyesh Ray


    Full Text Available This research studies an alternative to the slider-crank mechanism for internal combustion engines, which was proposed by the Wiseman Technologies Inc. Their design involved replacing the crankshaft with a hypocycloid gear assembly. The unique hypocycloid gear arrangement allowed the piston and connecting rod to move in a straight line creating a perfect sinusoidal motion, without any side loads. In this work, the Wiseman hypocycloid engine was modeled in a commercial engine simulation software and compared to slider-crank engine of the same size. The engine’s performance was studied, while operating on diesel, ethanol, and gasoline fuel. Furthermore, a scaling analysis on the Wiseman engine prototypes was carried out to understand how the performance of the engine is affected by increasing the output power and cylinder displacement. It was found that the existing 30cc Wiseman engine produced about 7% less power at peak speeds than the slider-crank engine of the same size. These results were concurrent with the dynamometer tests performed in the past. It also produced lower torque and was about 6% less fuel efficient than the slider-crank engine. The four-stroke diesel variant of the same Wiseman engine performed better than the two-stroke gasoline version. The Wiseman engine with a contra piston (that allowed to vary the compression ratio showed poor fuel efficiency but produced higher torque when operating on E85 fuel. It also produced about 1.4% more power than while running on gasoline. While analyzing effects of the engine size on the Wiseman hypocycloid engine prototypes, it was found that the engines performed better in terms of power, torque, fuel efficiency, and cylinder brake mean effective pressure as the displacement increased. The 30 horsepower (HP conceptual Wiseman prototype, while operating on E85, produced the most optimum results in all aspects, and the diesel test for the same engine proved to be the most fuel efficient.

  7. Visualization and simulation of complex flows in biomedical engineering

    CERN Document Server

    Imai, Yohsuke; Ishikawa, Takuji; Oliveira, Mónica


    This book focuses on the most recent advances in the application of visualization and simulation methods to understand the flow behavior of complex fluids used in biomedical engineering and other related fields. It shows the physiological flow behavior in large arteries, microcirculation, respiratory systems and in biomedical microdevices.

  8. Biomedical applications of control engineering

    CERN Document Server

    Hacısalihzade, Selim S


    Biomedical Applications of Control Engineering is a lucidly written textbook for graduate control engin­eering and biomedical engineering students as well as for medical prac­ti­tioners who want to get acquainted with quantitative methods. It is based on decades of experience both in control engineering and clinical practice.   The book begins by reviewing basic concepts of system theory and the modeling process. It then goes on to discuss control engineering application areas like ·         Different models for the human operator, ·         Dosage and timing optimization in oral drug administration, ·         Measuring symptoms of and optimal dopaminergic therapy in Parkinson’s disease, ·         Measure­ment and control of blood glucose le­vels both naturally and by means of external controllers in diabetes, and ·         Control of depth of anaesthesia using inhalational anaesthetic agents like sevoflurane using both fuzzy and state feedback controllers....

  9. Front panel engineering with CAD simulation tool (United States)

    Delacour, Jacques; Ungar, Serge; Mathieu, Gilles; Hasna, Guenther; Martinez, Pascal; Roche, Jean-Christophe


    THe progress made recently in display technology covers many fields of application. The specification of radiance, colorimetry and lighting efficiency creates some new challenges for designers. Photometric design is limited by the capability of correctly predicting the result of a lighting system, to save on the costs and time taken to build multiple prototypes or bread board benches. The second step of the research carried out by company OPTIS is to propose an optimization method to be applied to the lighting system, developed in the software SPEOS. The main features of the tool requires include the CAD interface, to enable fast and efficient transfer between mechanical and light design software, the source modeling, the light transfer model and an optimization tool. The CAD interface is mainly a prototype of transfer, which is not the subjects here. Photometric simulation is efficiently achieved by using the measured source encoding and a simulation by the Monte Carlo method. Today, the advantages and the limitations of the Monte Carlo method are well known. The noise reduction requires a long calculation time, which increases with the complexity of the display panel. A successful optimization is difficult to achieve, due to the long calculation time required for each optimization pass including a Monte Carlo simulation. The problem was initially defined as an engineering method of study. The experience shows that good understanding and mastering of the phenomenon of light transfer is limited by the complexity of non sequential propagation. The engineer must call for the help of a simulation and optimization tool. The main point needed to be able to perform an efficient optimization is a quick method for simulating light transfer. Much work has been done in this area and some interesting results can be observed. It must be said that the Monte Carlo method wastes time calculating some results and information which are not required for the needs of the simulation

  10. Application of physics engines in virtual worlds (United States)

    Norman, Mark; Taylor, Tim


    Dynamic virtual worlds potentially can provide a much richer and more enjoyable experience than static ones. To realize such worlds, three approaches are commonly used. The first of these, and still widely applied, involves importing traditional animations from a modeling system such as 3D Studio Max. This approach is therefore limited to predefined animation scripts or combinations/blends thereof. The second approach involves the integration of some specific-purpose simulation code, such as car dynamics, and is thus generally limited to one (class of) application(s). The third approach involves the use of general-purpose physics engines, which promise to enable a range of compelling dynamic virtual worlds and to considerably speed up development. By far the largest market today for real-time simulation is computer games, revenues exceeding those of the movie industry. Traditionally, the simulation is produced by game developers in-house for specific titles. However, off-the-shelf middleware physics engines are now available for use in games and related domains. In this paper, we report on our experiences of using middleware physics engines to create a virtual world as an interactive experience, and an advanced scenario where artificial life techniques generate controllers for physically modeled characters.

  11. Modelling and Simulation of Search Engine (United States)

    Nasution, Mahyuddin K. M.


    The best tool currently used to access information is a search engine. Meanwhile, the information space has its own behaviour. Systematically, an information space needs to be familiarized with mathematics so easily we identify the characteristics associated with it. This paper reveal some characteristics of search engine based on a model of document collection, which are then estimated the impact on the feasibility of information. We reveal some of characteristics of search engine on the lemma and theorem about singleton and doubleton, then computes statistically characteristic as simulating the possibility of using search engine. In this case, Google and Yahoo. There are differences in the behaviour of both search engines, although in theory based on the concept of documents collection.

  12. Industrial and Systems Engineering Applications in NASA (United States)

    Shivers, Charles H.


    A viewgraph presentation on the many applications of Industrial and Systems Engineering used for safe NASA missions is shown. The topics include: 1) NASA Information; 2) Industrial Engineering; 3) Systems Engineering; and 4) Major NASA Programs.

  13. Numerical simulations of pulsejet engines (United States)

    Geng, Tao

    The pulsejet has recently received more research interests due to its simple design, which can be developed into low-cost micro-scale propulsion devices for use in many of today's new applications such as UAVs. However, the relatively low thermal efficiency of pulsejets has always been the major obstacle in their development. The goal of this research is to investigate the possibility of using pulsejets in certain applications where the pulsejet can trade its low efficiency with low cost, simple design, and light weight. This work investigates pulsejet operation in a combined experimental and numerical approach, although the focus here is on the computational research. The fluid mechanics, acoustics, and chemical kinetics are studied numerically to understand the physics behind pulsejets and their operations. The research objectives include miniaturization of valveless pulsejets, acoustics model developments for both valved and valveless pulsejets, obtaining preliminary thrust performance data on micro-scale pulsejets, and finally, the formation of the starting vortex ring and its effect on pulsejet thrust.

  14. Simulation of diesel engine energy conversion processes

    Directory of Open Access Journals (Sweden)

    А. С. Афанасьев


    Full Text Available In order to keep diesel engines in good working order the troubleshooting methods shall be improved. For their further improvement by parameters of associated processes a need has arisen to develop a diesel engine troubleshooting method based on time parameters of operating cycle. For such method to be developed a computational experiment involving simulation of diesel engine energy conversion processes has been carried out. The simulation was based on the basic mathematical model of reciprocating internal combustion engines, representing a closed system of equations and relationships. The said model has been supplemented with the engine torque dynamics taking into account the current values of in-cylinder processes with different amounts of fuel injected, including zero feed.The torque values obtained by the in-cylinder pressure conversion does not account for mechanical losses, which is why the base simulation program has been supplemented with calculations for the friction and pumping forces. In order to determine the indicator diagram of idle cylinder a transition to zero fuel feed mode and exclusion of the combustion process from calculation have been provisioned.

  15. Diesel Engine Light Truck Application

    Energy Technology Data Exchange (ETDEWEB)



    The Diesel Engine Light Truck Application (DELTA) program consists of two major contracts with the Department of Energy (DOE). The first one under DE-FC05-97-OR22606, starting from 1997, was completed in 2001, and consequently, a final report was submitted to DOE in 2003. The second part of the contract was under DE-FC05-02OR22909, covering the program progress from 2002 to 2007. This report is the final report of the second part of the program under contract DE-FC05-02OR22909. During the course of this contract, the program work scope and objectives were significantly changed. From 2002 to 2004, the DELTA program continued working on light-duty engine development with the 4.0L V6 DELTA engine, following the accomplishments made from the first part of the program under DE-FC05-97-OR22606. The program work scope in 2005-2007 was changed to the Diesel Particulate Filter (DPF) soot layer characterization and substrate material assessment. This final report will cover two major technical tasks. (1) Continuation of the DELTA engine development to demonstrate production-viable diesel engine technologies and to demonstrate emissions compliance with significant fuel economy advantages, covering progress made from 2002 to 2004. (2) DPF soot layer characterization and substrate material assessment from 2005-2007.

  16. Interactive Mathematica Simulations in Chemical Engineering Courses (United States)

    Falconer, John L.; Nicodemus, Garret D.


    Interactive Mathematica simulations with graphical displays of system behavior are an excellent addition to chemical engineering courses. The Manipulate command in Mathematica creates on-screen controls that allow users to change system variables and see the graphical output almost instantaneously. They can be used both in and outside class. More…

  17. Software for Engineering Simulations of a Spacecraft (United States)

    Shireman, Kirk; McSwain, Gene; McCormick, Bernell; Fardelos, Panayiotis


    Spacecraft Engineering Simulation II (SES II) is a C-language computer program for simulating diverse aspects of operation of a spacecraft characterized by either three or six degrees of freedom. A functional model in SES can include a trajectory flight plan; a submodel of a flight computer running navigational and flight-control software; and submodels of the environment, the dynamics of the spacecraft, and sensor inputs and outputs. SES II features a modular, object-oriented programming style. SES II supports event-based simulations, which, in turn, create an easily adaptable simulation environment in which many different types of trajectories can be simulated by use of the same software. The simulation output consists largely of flight data. SES II can be used to perform optimization and Monte Carlo dispersion simulations. It can also be used to perform simulations for multiple spacecraft. In addition to its generic simulation capabilities, SES offers special capabilities for space-shuttle simulations: for this purpose, it incorporates submodels of the space-shuttle dynamics and a C-language version of the guidance, navigation, and control components of the space-shuttle flight software.

  18. Soil variability in engineering applications (United States)

    Vessia, Giovanna


    Natural geomaterials, as soils and rocks, show spatial variability and heterogeneity of physical and mechanical properties. They can be measured by in field and laboratory testing. The heterogeneity concerns different values of litho-technical parameters pertaining similar lithological units placed close to each other. On the contrary, the variability is inherent to the formation and evolution processes experienced by each geological units (homogeneous geomaterials on average) and captured as a spatial structure of fluctuation of physical property values about their mean trend, e.g. the unit weight, the hydraulic permeability, the friction angle, the cohesion, among others. The preceding spatial variations shall be managed by engineering models to accomplish reliable designing of structures and infrastructures. Materon (1962) introduced the Geostatistics as the most comprehensive tool to manage spatial correlation of parameter measures used in a wide range of earth science applications. In the field of the engineering geology, Vanmarcke (1977) developed the first pioneering attempts to describe and manage the inherent variability in geomaterials although Terzaghi (1943) already highlighted that spatial fluctuations of physical and mechanical parameters used in geotechnical designing cannot be neglected. A few years later, Mandelbrot (1983) and Turcotte (1986) interpreted the internal arrangement of geomaterial according to Fractal Theory. In the same years, Vanmarcke (1983) proposed the Random Field Theory providing mathematical tools to deal with inherent variability of each geological units or stratigraphic succession that can be resembled as one material. In this approach, measurement fluctuations of physical parameters are interpreted through the spatial variability structure consisting in the correlation function and the scale of fluctuation. Fenton and Griffiths (1992) combined random field simulation with the finite element method to produce the Random

  19. Handbook of bioplastics and biocomposites engineering applications

    National Research Council Canada - National Science Library

    Pilla, Srikanth


    "The Handbook of Bioplastics & Biocomposites Engineering Applications brings together scientists, from academia and industries, to report on current research and applications, in the bioplastics and biocomposites arena...

  20. Coastal Processes with Engineering Applications (United States)

    Dean, Robert G.; Dalrymple, Robert A.


    The world's coastlines, dividing land from sea, are geological environments that are unique in their composition and the physical processes affecting them. At the dynamically active intersection of land and the oceans, humans have been building structures throughout history. Initially used for naval and commercial purposes, more recently recreation and tourism have increased activity in the coastal zone dramatically. Shoreline development is now causing a significant conflict with natural coastal processes. This text on coastal engineering will help the reader understand these coastal processes and develop strategies to cope effectively with shoreline erosion. The book is organized in four parts: (1) an overview of coastal engineering, using case studies to illustrate problems; (2) hydrodynamics of the coastal zone, reviewing storm surges, water waves, and low frequency motions within the nearshore and surf zone; (3) coastal responses including equilibrium beach profiles and sediment transport; (4) applications such as erosion mitigation, beach nourishment, coastal armoring, tidal inlets, and shoreline management.

  1. Nuclear engine system simulation (NESS) program update (United States)

    Scheil, Christine M.; Pelaccio, Dennis G.; Petrosky, Lyman J.


    The second phase of development of a Nuclear Thermal Propulsion (NTP) engine system design analysis code has been completed. The standalone, versatile Nuclear Engine System Simulation (NESS) code provides an accurate, detailed assessment of engine system operating performance, weight, and sizes. The critical information is required to support ongoing and future engine system and stage design study efforts. This recent development effort included incorporation of an updated solid-core nuclear thermal reactor model that yields a reduced core weight and higher fuel power density when compared to a NERVA type reactor. NESS can now analyze expander, gas generator, and bleed cycles, along with multi-redundant propellant pump feed systems. Performance and weight of efficient multi-stage axial turbopump can now be determined, in addition to the traditional centrifugal pump. Key code outputs include reactor operating charactertistics and weights and well as engine system parameters such as performance, weights, dimensions, pressures, temperatures, mass flows and turbopump operating characteristics for both design and off-design operating conditions. Representative NTP engine system designs are also shown. An overview of NESS methodology and capabilities is presented in this paper, with special emphasis being placed on recent code developments.

  2. Internal Combustion Engine Principles with Vehicle Applications

    DEFF Research Database (Denmark)

    Sorenson, Spencer C

    The book is an introductory text on the subject of internal combustion engines, intended for use in engineering courses at the senior or introductory graduate student level. The focus in on describing the basic principles of engine operation on a broad basis, to provide a foundation for further...... exchange processes, combustion in different engine types, exhaust emissions, engine control including mean value engine models, pressure charging, fuels and fuel systems, balancing, friction, and heat transfer. In addition, methods to establish the connection between engine characteristics and vehicle...... study, research and development. The goal is to describe the main variables involved in engine operation of different engine types, and how their interaction determines engine performance. Topics included are: general engine parameters, thermodynamic cycles including simple engine simulation, air...

  3. Alya: Towards Exascale for Engineering Simulation Codes

    CERN Document Server

    Vazquez, Mariano; Koric, Seid; Artigues, Antoni; Aguado-Sierra, Jazmin; Aris, Ruth; Mira, Daniel; Calmet, Hadrien; Cucchietti, Fernando; Owen, Herbert; Taha, Ahmed; Cela, Jose Maria


    Alya is the BSC in-house HPC-based multi-physics simulation code. It is designed from scratch to run efficiently in parallel supercomputers, solving coupled problems. The target domain is engineering, with all its particular features: complex geome- tries and unstructured meshes, coupled multi-physics with exotic coupling schemes and Physical models, ill-posed problems, flexibility needs for rapidly including new models, etc. Since its conception in 2004, Alya has shown scaling behaviour in an increasing number of cores. In this paper, we present its performance up to 100.000 cores in Blue Waters, the NCSA supercomputer. The selected tests are representative of the engineering world, all the problematic features included: incompressible flow in a hu- man respiratory system, low Mach combustion problem in a kiln furnace and coupled electro-mechanical problem in a heart. We show scalability plots for all cases, discussing all the aspects of such kind of simulations, including solvers convergence.

  4. An Emotional Engine for Behavior Simulators

    Directory of Open Access Journals (Sweden)

    Santiago García Carbajal


    Full Text Available Interpreting, modeling and representing emotions is a key feature of new generation games. This paper describes the first version of the Emotional Engine we have developed as a component of more complex behavior simulators. The purpose of this module is to manage the state and behavior of the characters present in a scene while they interact with a human user. We use preexistent language recognition libraries like Windows™ Speech API, and Kinect™ devices to communicate real humans with artificial characters participating in a virtual scene. The Emotional Engine works upon numeric variables extracted from such devices and calculated after some natural language interpretation process. It then produces numerical results that lead the behavior, modify both the verbal and body language of the characters, and influence the general evolution of the scene that takes place inside the simulator. This paper presents the system architecture and discusses some key components, such as the Language Interpretation and the Body Language Interpreter modules.

  5. Virtual environment application with partial gravity simulation (United States)

    Ray, David M.; Vanchau, Michael N.


    To support manned missions to the surface of Mars and missions requiring manipulation of payloads and locomotion in space, a training facility is required to simulate the conditions of both partial and microgravity. A partial gravity simulator (Pogo) which uses pneumatic suspension is being studied for use in virtual reality training. Pogo maintains a constant partial gravity simulation with a variation of simulated body force between 2.2 and 10 percent, depending on the type of locomotion inputs. this paper is based on the concept and application of a virtual environment system with Pogo including a head-mounted display and glove. The reality engine consists of a high end SGI workstation and PC's which drive Pogo's sensors and data acquisition hardware used for tracking and control. The tracking system is a hybrid of magnetic and optical trackers integrated for this application.


    Directory of Open Access Journals (Sweden)

    Angelo Fabbri


    Full Text Available In agri-food engineering many complex problems arise in plant and process design. Specifically the designer has to deal with fluid dynamics, thermal or mechanical problems, often characterized by physics coupling, non-linearity, irregular geometry, anisotropy and in definitive rather high complexity. In recent years, the ever growing availability of computational power at low cost, made these problems more often approached with numerical simulation techniques. Mainly in terms of finite elements and finite volumes. In this paper the fundamentals of numerical methods are briefly recalled and a discussion about their possibility of application in the food and agricultural engineering is developed.

  7. Inequalities with applications to engineering

    CERN Document Server

    Cloud, Michael J; Lebedev, Leonid P


    This book offers a concise introduction to mathematical inequalities for graduate students and researchers in the fields of engineering and applied mathematics. It begins by reviewing essential facts from algebra and calculus and proceeds with a presentation of the central inequalities of applied analysis, illustrating a wide variety of practical applications. The text provides a gentle introduction to abstract spaces, such as metric, normed, and inner product spaces. It also provides full coverage of the central inequalities of applied analysis, such as Young's inequality, the inequality of the means, Hölder's inequality, Minkowski's inequality, the Cauchy–Schwarz inequality, Chebyshev's inequality, Jensen's inequality, and the triangle inequality. The second edition features extended coverage of applications, including continuum mechanics and interval analysis. It also includes many additional examples and exercises with hints and full solutions that may appeal to upper-level undergraduate and graduate...

  8. Recent advances in electrical engineering and control applications

    CERN Document Server

    Bououden, Sofiane; Zelinka, Ivan


    This book of proceedings includes papers presenting the state of art in electrical engineering and control theory as well as their applications. The topics focus on classical as well as modern methods for modeling, control, identification and simulation of complex systems with applications in science and engineering. The papers were selected from the hottest topic areas, such as control and systems engineering, renewable energy, faults diagnosis—faults tolerant control, large-scale systems, fractional order systems, unconventional algorithms in control engineering, signals and communications. The control and design of complex systems dynamics, analysis and modeling of its behavior and structure is vitally important in engineering, economics and in science generally science today. Examples of such systems can be seen in the world around us and are a part of our everyday life. Application of modern methods for control, electronics, signal processing and more can be found in our mobile phones, car engines, hom...

  9. Simulation Engine for Fluid Solid Interaction Problems and its Application to the Modelling of Air Blast Hazards in Block Cave Mining. (United States)

    Galindo Torres, S. A.; Scheuermann, A.; Ruest, M.


    Air blasts that may occur in a block caving mining operation represent a significant hazard for personnel as well as to mining infrastructure. Uncontrolled caving of a large volume of broken rock into a mine void causes compression of the air within, forcing it to flow at high velocities into connecting tunnels such as extraction points beneath the cave or observation points intersecting the cave. This high velocity flow of air can cause injury to personnel and significant damage to equipment. In this presentation, we introduce a simulation engine for the air blast problem. The solid material is modelled using the Discrete Element Method (DEM) and the fluid (air) is modelled using the Lattice Boltzmann Method (LBM). The combined DEM-LBM approach has been introduced by our group at the University of Queensland[1]. LBM allows us to introduce an appropriate equation of state for the air that simulates compressibility as a function of the speed of sound. Validation examples are presented to justify the use of this tool for an air blasting situation. A section view of one simulation is provided in Fig 1. An investigation into the risk of developing air pockets as a function of fragment size distribution is also conducted and described. The fragment size distribution can be assessed during mining and the risk of air pockets forming (and consequently of air blast occurring) can be deduced and mitigation measures put in place. The effect of other key variables that can be determined from geotechnical investigations, such as fracture frequency, are also systematically explored. It is expected that the results of this study can elucidate key features of the air blasting phenomenon in order to formulate safer mining protocols. references 1. Galindo-Torres, S.A., A coupled Discrete Element Lattice Boltzmann Method for the simulation of fluid-solid interaction with particles of general shapes. Computer Methods in Applied Mechanics and Engineering, 2013. 265(0): p. 107-119.

  10. Simulation teaching method in Engineering Optics (United States)

    Lu, Qieni; Wang, Yi; Li, Hongbin


    We here introduce a pedagogical method of theoretical simulation as one major means of the teaching process of "Engineering Optics" in course quality improvement action plan (Qc) in our school. Students, in groups of three to five, complete simulations of interference, diffraction, electromagnetism and polarization of light; each student is evaluated and scored in light of his performance in the interviews between the teacher and the student, and each student can opt to be interviewed many times until he is satisfied with his score and learning. After three years of Qc practice, the remarkable teaching and learning effect is obatined. Such theoretical simulation experiment is a very valuable teaching method worthwhile for physical optics which is highly theoretical and abstruse. This teaching methodology works well in training students as to how to ask questions and how to solve problems, which can also stimulate their interest in research learning and their initiative to develop their self-confidence and sense of innovation.

  11. Rainfall simulation for environmental application

    Energy Technology Data Exchange (ETDEWEB)

    Shriner, D.S.; Abner, C.H.; Mann, L.K.


    Rain simulation systems have been designed for field and greenhouse studies which have the capability of reproducing the physical and chemical characteristics of natural rainfall. The systems permit the simulation of variations in rainfall and droplet size similar to that of natural precipitation. The systems are completely automatic and programmable, allowing unattended operation for periods of up to one week, and have been used to expose not only vegetation but also soils and engineering materials, making them versatile tools for studies involving simulated precipitation.

  12. Computer simulation in physics and engineering

    CERN Document Server

    Steinhauser, Martin Oliver


    This work is a needed reference for widely used techniques and methods of computer simulation in physics and other disciplines, such as materials science. The work conveys both: the theoretical foundations of computer simulation as well as applications and "tricks of the trade", that often are scattered across various papers. Thus it will meet a need and fill a gap for every scientist who needs computer simulations for his/her task at hand. In addition to being a reference, case studies and exercises for use as course reading are included.

  13. Cardiovascular system simulation in biomedical engineering education. (United States)

    Rideout, V. C.


    Use of complex cardiovascular system models, in conjunction with a large hybrid computer, in biomedical engineering courses. A cardiovascular blood pressure-flow model, driving a compartment model for the study of dye transport, was set up on the computer for use as a laboratory exercise by students who did not have the computer experience or skill to be able to easily set up such a simulation involving some 27 differential equations running at 'real time' rate. The students were given detailed instructions regarding the model, and were then able to study effects such as those due to septal and valve defects upon the pressure, flow, and dye dilution curves. The success of this experiment in the use of involved models in engineering courses was such that it seems that this type of laboratory exercise might be considered for use in physiology courses as an adjunct to animal experiments.

  14. Large Eddy Simulation (LES for IC Engine Flows

    Directory of Open Access Journals (Sweden)

    Kuo Tang-Wei


    Full Text Available Numerical computations are carried out using an engineering-level Large Eddy Simulation (LES model that is provided by a commercial CFD code CONVERGE. The analytical framework and experimental setup consist of a single cylinder engine with Transparent Combustion Chamber (TCC under motored conditions. A rigorous working procedure for comparing and analyzing the results from simulation and high speed Particle Image Velocimetry (PIV experiments is documented in this work. The following aspects of LES are analyzed using this procedure: number of cycles required for convergence with adequate accuracy; effect of mesh size, time step, sub-grid-scale (SGS turbulence models and boundary condition treatments; application of the proper orthogonal decomposition (POD technique.

  15. Advancements in real-time engine simulation technology (United States)

    Szuch, J. R.


    The approaches used to develop real-time engine simulations are reviewed. Both digital and hybrid (analog and digital) techniques are discussed and specific examples of each are cited. These approaches are assessed from the standpoint of their usefulness for digital engine control development. A number of NASA-sponsored simulation research activities, aimed at exploring real-time simulation techniques, are described. These include the development of a microcomputer-based, parallel processor system for real-time engine simulation.

  16. Applications of smart materials in structural engineering. (United States)


    With the development of materials and technology, many new materials find their applications in civil engineering to deal with the deteriorating infrastructure. Smart material is a promising example that deserves a wide focus, from research to applic...

  17. Geothermal engineering fundamentals and applications

    CERN Document Server

    Watson, Arnold


    This book explains the engineering required to bring geothermal resources into use. The book covers specifically engineering aspects that are unique to geothermal engineering, such as measurements in wells and their interpretation, transport of near-boiling water through long pipelines, turbines driven by fluids other than steam, and project economics. The explanations are reinforced by drawing comparisons with other energy industries.

  18. LCCP Desktop Application v1.0 Engineering Reference

    Energy Technology Data Exchange (ETDEWEB)

    Beshr, Mohamed [Univ. of Maryland, College Park, MD (United States); Aute, Vikrant [Univ. of Maryland, College Park, MD (United States)


    This Life Cycle Climate Performance (LCCP) Desktop Application Engineering Reference is divided into three parts. The first part of the guide, consisting of the LCCP objective, literature review, and mathematical background, is presented in Sections 2-4. The second part of the guide (given in Sections 5-10) provides a description of the input data required by the LCCP desktop application, including each of the input pages (Application Information, Load Information, and Simulation Information) and details for interfacing the LCCP Desktop Application with the VapCyc and EnergyPlus simulation programs. The third part of the guide (given in Section 11) describes the various interfaces of the LCCP code.

  19. CFD Simulation of Liquid Rocket Engine Injectors (United States)

    Farmer, Richard; Cheng, Gary; Chen, Yen-Sen; Garcia, Roberto (Technical Monitor)


    Detailed design issues associated with liquid rocket engine injectors and combustion chamber operation require CFD methodology which simulates highly three-dimensional, turbulent, vaporizing, and combusting flows. The primary utility of such simulations involves predicting multi-dimensional effects caused by specific injector configurations. SECA, Inc. and Engineering Sciences, Inc. have been developing appropriate computational methodology for NASA/MSFC for the past decade. CFD tools and computers have improved dramatically during this time period; however, the physical submodels used in these analyses must still remain relatively simple in order to produce useful results. Simulations of clustered coaxial and impinger injector elements for hydrogen and hydrocarbon fuels, which account for real fluid properties, is the immediate goal of this research. The spray combustion codes are based on the FDNS CFD code' and are structured to represent homogeneous and heterogeneous spray combustion. The homogeneous spray model treats the flow as a continuum of multi-phase, multicomponent fluids which move without thermal or velocity lags between the phases. Two heterogeneous models were developed: (1) a volume-of-fluid (VOF) model which represents the liquid core of coaxial or impinger jets and their atomization and vaporization, and (2) a Blob model which represents the injected streams as a cloud of droplets the size of the injector orifice which subsequently exhibit particle interaction, vaporization, and combustion. All of these spray models are computationally intensive, but this is unavoidable to accurately account for the complex physics and combustion which is to be predicted, Work is currently in progress to parallelize these codes to improve their computational efficiency. These spray combustion codes were used to simulate the three test cases which are the subject of the 2nd International Workshop on-Rocket Combustion Modeling. Such test cases are considered by

  20. Nonlinear approaches in engineering applications 2

    CERN Document Server

    Jazar, Reza N


    Provides updated principles and applications of the nonlinear approaches in solving engineering and physics problems Demonstrates how nonlinear approaches may open avenues to better, safer, cheaper systems with less energy consumption Has a strong emphasis on the application, physical meaning, and methodologies of nonlinear approaches in different engineering and science problems

  1. Biomedical Applications of Simulated Environments .


    W. Selvamurthy


    Environmental physiology assumes great significance in our national context of the diverse climatic conditions prevailing in different regions. Troops have to operate in diverse environmental conditions guarding the frontiers. Hence, the research in this area has been focused on the usage of field studies in the natural environments or simulated environments in the laboratory. Besides, the application of the simulation chambers in the research on the physiological effects of diverse en...

  2. Numerical simulations of coupled problems in engineering

    CERN Document Server


    This book presents and discusses mathematical models, numerical methods and computational techniques used for solving coupled problems in science and engineering. It takes a step forward in the formulation and solution of real-life problems with a multidisciplinary vision, accounting for all of the complex couplings involved in the physical description. Simulation of multifaceted physics problems is a common task in applied research and industry. Often a suitable solver is built by connecting together several single-aspect solvers into a network. In this book, research in various fields was selected for consideration: adaptive methodology for multi-physics solvers, multi-physics phenomena and coupled-field solutions, leading to computationally intensive structural analysis. The strategies which are used to keep these problems computationally affordable are of special interest, and make this an essential book.

  3. Experiences on dynamic simulation software in chemical engineering education


    Komulainen, Tiina M.; Enemark-Rasmussen, Rasmus; Sin, Gürkan; Fletcher, John P.; Cameron, David


    Commercial process simulators are increasing interest in the chemical engineer education. In this paper, the use of commercial dynamic simulation software, D-SPICE® and K-Spice®, for three different chemical engineering courses is described and discussed. The courses cover the following topics: basic chemical engineering, operability and safety analysis and process control. User experiences from both teachers and students are presented. The benefits of dynamic simulation as an additional teac...

  4. High Fidelity Simulation of Atomization in Diesel Engine Sprays (United States)


    ARL-RP-0555 ● SEP 2015 US Army Research Laboratory High Fidelity Simulation of Atomization in Diesel Engine Sprays by L Bravo...ARL-RP-0555 ● SEP 2015 US Army Research Laboratory High Fidelity Simulation of Atomization in Diesel Engine Sprays by L...Simulation of Atomization in Diesel Engine Sprays 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) L Bravo, CB Ivey, D

  5. Simulation on microscopic deformation behavior of engine gasket


    Cao Ke; Zhao Yixi; Jin Sun


    Engine gasket is the thin steel plate with coatings. Its compressive deformation affects the height of engine assembly, which changes combustion chamber’s volume and then influences engine performance. In this paper, the assembly simulation of head, block and gasket was studied. Then a further simulation takes the thin coatings on steel sheet into consideration. In the second simulation, gasket’s partial micro-model in micron-scale meshes was established and deformation of coatings was analys...

  6. Biocatalysts: application and engineering for industrial purposes. (United States)

    Jemli, Sonia; Ayadi-Zouari, Dorra; Hlima, Hajer Ben; Bejar, Samir


    Enzymes are widely applied in various industrial applications and processes, including the food and beverage, animal feed, textile, detergent and medical industries. Enzymes screened from natural origins are often engineered before entering the market place because their native forms do not meet the requirements for industrial application. Protein engineering is concerned with the design and construction of novel enzymes with tailored functional properties, including stability, catalytic activity, reaction product inhibition and substrate specificity. Two broad approaches have been used for enzyme engineering, namely, rational design and directed evolution. The powerful and revolutionary techniques so far developed for protein engineering provide excellent opportunities for the design of industrial enzymes with specific properties and production of high-value products at lower production costs. The present review seeks to highlight the major fields of enzyme application and to provide an updated overview on previous protein engineering studies wherein natural enzymes were modified to meet the operational conditions required for industrial application.

  7. A Solar Sailcraft Simulation Application (United States)

    Celeda, Tomáš


    An application was created to encourage students' practical knowledge of gravitational fields, the law of conservation of energy and other phenomena, such as gravitational slingshots. The educational software simulates the flight of a solar sail spacecraft between two planets of the Solar System using the laws of gravity and radiation…

  8. Application of Advanced Materials in Petroleum Engineering (United States)

    Zhao, Gufan; Di, Weina; Wang, Minsheng

    With the background of increasing requirements on the petroleum engineering technology from more high demanding exploration targets, global oil companies and oil service companies are making more efforts on both R&D and application of new petroleum engineering technology. Advanced materials always have a decisive role in the functionality of a new product. Technology transplantation has become the important means of innovation in oil and gas industry. Here, we mainly discuss the properties and scope of application of several advanced materials. Based on the material requirements in petroleum engineering, we provide several candidates for downhole electronics protection, drilling fluid additives, downhole tools, etc. Based on the analysis of petroleum engineering technology characteristics, this paper made analysis and research on such advanced materials as new insulation materials, functional gradient materials, self-healing polymers, and introduced their application prospect in petroleum engineering in terms of specific characteristics.

  9. Large Eddy Simulation of Engineering Flows: A Bill Reynolds Legacy. (United States)

    Moin, Parviz


    The term, Large eddy simulation, LES, was coined by Bill Reynolds, thirty years ago when he and his colleagues pioneered the introduction of LES in the engineering community. Bill's legacy in LES features his insistence on having a proper mathematical definition of the large scale field independent of the numerical method used, and his vision for using numerical simulation output as data for research in turbulence physics and modeling, just as one would think of using experimental data. However, as an engineer, Bill was pre-dominantly interested in the predictive capability of computational fluid dynamics and in particular LES. In this talk I will present the state of the art in large eddy simulation of complex engineering flows. Most of this technology has been developed in the Department of Energy's ASCI Program at Stanford which was led by Bill in the last years of his distinguished career. At the core of this technology is a fully implicit non-dissipative LES code which uses unstructured grids with arbitrary elements. A hybrid Eulerian/ Largangian approach is used for multi-phase flows, and chemical reactions are introduced through dynamic equations for mixture fraction and reaction progress variable in conjunction with flamelet tables. The predictive capability of LES is demonstrated in several validation studies in flows with complex physics and complex geometry including flow in the combustor of a modern aircraft engine. LES in such a complex application is only possible through efficient utilization of modern parallel super-computers which was recognized and emphasized by Bill from the beginning. The presentation will include a brief mention of computer science efforts for efficient implementation of LES.

  10. Growing tissues in real and simulated microgravity: new methods for tissue engineering

    NARCIS (Netherlands)

    Grimm, D.; Wehland, M.; Pietsch, J.; Aleshcheva, G.; Wise, P.; van Loon, J.; Ulbrich, C.; Magnusson, N.E.; Infanger, M.; Bauer, J.


    Tissue engineering in simulated (s-) and real microgravity (r-μg) is currently a topic in Space medicine contributing to biomedical sciences and their applications on Earth. The principal aim of this review is to highlight the advances and accomplishments in the field of tissue engineering that

  11. Growing Tissues in Real and Simulated Microgravity: New Methods for Tissue Engineering

    NARCIS (Netherlands)

    Grimm, D.; Wehland, M.; Pietsch, J.; Aleshcheva, G.; Wise, P.; van Loon, J.J.W.A.; Ulbrich, C.; Magnusson, N.E.; Infanger, M.; Bauer, J.


    Tissue engineering in simulated (s-) and real microgravity (r-μg) is currently a topic in Space medicine contributing to biomedical sciences and their applications on Earth. The principal aim of this review is to highlight the advances and accomplishments in the field of tissue engineering that

  12. Large eddy simulation applications in gas turbines. (United States)

    Menzies, Kevin


    The gas turbine presents significant challenges to any computational fluid dynamics techniques. The combination of a wide range of flow phenomena with complex geometry is difficult to model in the context of Reynolds-averaged Navier-Stokes (RANS) solvers. We review the potential for large eddy simulation (LES) in modelling the flow in the different components of the gas turbine during a practical engineering design cycle. We show that while LES has demonstrated considerable promise for reliable prediction of many flows in the engine that are difficult for RANS it is not a panacea and considerable application challenges remain. However, for many flows, especially those dominated by shear layer mixing such as in combustion chambers and exhausts, LES has demonstrated a clear superiority over RANS for moderately complex geometries although at significantly higher cost which will remain an issue in making the calculations relevant within the design cycle.

  13. Solid fuel applications to transportation engines

    Energy Technology Data Exchange (ETDEWEB)

    Rentz, Richard L.; Renner, Roy A.


    The utilization of solid fuels as alternatives to liquid fuels for future transportation engines is reviewed. Alternative liquid fuels will not be addressed nor will petroleum/solid fuel blends except for the case of diesel engines. With respect to diesel engines, coal/oil mixtures will be addressed because of the high interest in this specific application as a result of the large number of diesel engines currently in transportation use. Final assessments refer to solid fuels only for diesel engines. The technical assessments of solid fuels utilization for transportation engines is summarized: solid fuel combustion in transportation engines is in a non-developed state; highway transportation is not amenable to solid fuels utilization due to severe environmental, packaging, control, and disposal problems; diesel and open-cycle gas turbines do not appear worthy of further development, although coal/oil mixtures for slow speed diesels may offer some promise as a transition technology; closed-cycle gas turbines show some promise for solid fuels utilization for limited applications as does the Stirling engine for use of cleaner solid fuels; Rankine cycle engines show good potential for limited applications, such as for locomotives and ships; and any development program will require large resources and sophisticated equipment in order to advance the state-of-the-art.

  14. Product Representation to support validation of simulation models in Computer aided engineering


    Kain, Andreas;Gaag, Andreas;Lindemann, Udo


    Computer aided engineering (CAE) provides proper means to support New Product Development (NPD) by simulation tools. Simulation furthers early identification of product characteristics to reduce costs and time. The applicability of simulation models in NPD strongly depends on their validity, thus validating a simulation poses a major issue to provide correct experimentation results. The authors propose a matrix based approach to combine solution neutral system representation, solution specifi...

  15. Application of neural networks in coastal engineering

    Digital Repository Service at National Institute of Oceanography (India)

    Mandal, S.

    methods. That is why it is becoming popular in various fields including coastal engineering. Waves and tides will play important roles in coastal erosion or accretion. This paper briefly describes the back-propagation neural networks and its application...

  16. The development and application of CFD technology in mechanical engineering (United States)

    Wei, Yufeng


    Computational Fluid Dynamics (CFD) is an analysis of the physical phenomena involved in fluid flow and heat conduction by computer numerical calculation and graphical display. The numerical method simulates the complexity of the physical problem and the precision of the numerical solution, which is directly related to the hardware speed of the computer and the hardware such as memory. With the continuous improvement of computer performance and CFD technology, it has been widely applied to the field of water conservancy engineering, environmental engineering and industrial engineering. This paper summarizes the development process of CFD, the theoretical basis, the governing equations of fluid mechanics, and introduces the various methods of numerical calculation and the related development of CFD technology. Finally, CFD technology in the mechanical engineering related applications are summarized. It is hoped that this review will help researchers in the field of mechanical engineering.

  17. Growing Tissues in Real and Simulated Microgravity: New Methods for Tissue Engineering


    Grimm, Daniela; Wehland, Markus; Pietsch, Jessica; Aleshcheva, Ganna; Wise, Petra; van Loon, Jack; Ulbrich, Claudia; Magnusson, Nils E.; Infanger, Manfred; Bauer, Johann


    Tissue engineering in simulated (s-) and real microgravity (r-μg) is currently a topic in Space medicine contributing to biomedical sciences and their applications on Earth. The principal aim of this review is to highlight the advances and accomplishments in the field of tissue engineering that could be achieved by culturing cells in Space or by devices created to simulate microgravity on Earth. Understanding the biology of three-dimensional (3D) multicellular structures is very important for...

  18. Basic Mechanics with Engineering Applications

    CERN Document Server

    Jones, J; Fawcett, J N


    This book gives a sufficient grounding in mechanics for engineers to tackle a significant range of problems encountered in the design and specification of simple structures and machines. It also provides an excellent background for students wishing to progress to more advanced studies in three-dimensional mechanics.

  19. Interactive, Secure Web-enabled Aircraft Engine Simulation Using XML Databinding Integration (United States)

    Lin, Risheng; Afjeh, Abdollah A.


    This paper discusses the detailed design of an XML databinding framework for aircraft engine simulation. The framework provides an object interface to access and use engine data. while at the same time preserving the meaning of the original data. The Language independent representation of engine component data enables users to move around XML data using HTTP through disparate networks. The application of this framework is demonstrated via a web-based turbofan propulsion system simulation using the World Wide Web (WWW). A Java Servlet based web component architecture is used for rendering XML engine data into HTML format and dealing with input events from the user, which allows users to interact with simulation data from a web browser. The simulation data can also be saved to a local disk for archiving or to restart the simulation at a later time.

  20. Understanding molecular simulation: from algorithms to applications

    NARCIS (Netherlands)

    Frenkel, D.; Smit, B.


    Second and revised edition Understanding Molecular Simulation: From Algorithms to Applications explains the physics behind the "recipes" of molecular simulation for materials science. Computer simulators are continuously confronted with questions concerning the choice of a particular technique

  1. TCC-III Engine Benchmark for Large-Eddy Simulation of IC Engine Flows

    Directory of Open Access Journals (Sweden)

    Schiffmann P.


    Full Text Available A collaborative effort is described to benchmark the TCC-III engine, and to illustrate the application of this data for the evaluation of sub-grid scale models and valve simulation details on the fidelity of Large-Eddy Simulations (LES. The TCC-III is a spark ignition 4-stroke 2-valve engine with a flat head and piston and is equipped with a full quartz liner for maximum optical access that allows high-speed flow measurements with Particle Image Velocimetry (PIV; the TCC-III has new valve seats and a modified intake-system compared to previous configurations. This work is an extension of a previous study at an engine speed of 800 RPM and an intake manifold pressure (MAP of 95 kPa, where a one-equation eddy viscosity LES model yielded accurate qualitative and quantitative predictions of ensemble averaged mean and RMS velocities during the intake and compression stroke. Here, experimental data were acquired with parametric variation of engine speed and intake manifold absolute pressure to assess the capability of LES models over a range of operating conditions of practical relevance. This paper focuses on the repeatability and accuracy of the measured PIV data, acquired at 1 300 RPM, at two different MAP (95 kPa and 40 kPa, and imaged at multiple data planes and crank angles. Two examples are provided, illustrating the application of this data to LES model development. In one example, the experimental data are used to distinguish between the efficacies of a one-equation eddy viscosity model versus a dynamic structure one-equation model for the sub-grid stresses. The second example addresses the effects of numerical intake-valve opening strategy and local mesh refinement in the valve curtain.

  2. Fuzzy logic applications in engineering science

    CERN Document Server

    Harris, J


    Fuzzy logic is a relatively new concept in science applications. Hitherto, fuzzy logic has been a conceptual process applied in the field of risk management. Its potential applicability is much wider than that, however, and its particular suitability for expanding our understanding of processes and information in science and engineering in our post-modern world is only just beginning to be appreciated. Written as a companion text to the author's earlier volume "An Introduction to Fuzzy Logic Applications", the book is aimed at professional engineers and students and those with an interest in exploring the potential of fuzzy logic as an information processing kit with a wide variety of practical applications in the field of engineering science and develops themes and topics introduced in the author's earlier text.

  3. Ceramics for Turbine Engine Applications. (United States)


    1909, Karl M a y b a c h (picture 20) founds his company "Luftfahrzeug-Motoren GmbH", which in 1912 is turned into " Maybach -Motoren GmbH...Germany 1909 Mercedes-Daimler 4 80 Germany 1912 Austro-Daimler 6 120 Austria 1915 Benz 6 160 Germany 1915 Rolls-Royce 6 100 Great Britain 1915 Maybach ...6 180 Germany 1916 Mercedes 6 180 Germany 1917 BMW 6 185 Germany 1917 Siddeley-Puma 6 250 Great Britain Fig. 16 1920 Maybach 6 260 Germany V-engines

  4. Lattice engineering technology and applications

    CERN Document Server

    Wang, Shumin


    This book contains comprehensive reviews of different technologies to harness lattice mismatch in semiconductor heterostructures and their applications in electronic and optoelectronic devices. While the book is a bit focused on metamorphic epitaxial growth, it also includes other methods like compliant substrate, selective area growth, wafer bonding and heterostructure nanowires etc. Basic knowledge on dislocations in semiconductors and innovative methods to eliminate threading dislocations are provided, and successful device applications are reviewed. It covers a variety of important semicon

  5. Metal Matrix Composites for Rocket Engine Applications (United States)

    McDonald, Kathleen R.; Wooten, John R.


    This document is from a presentation about the applications of Metal Matrix Composites (MMC) in rocket engines. Both NASA and the Air Force have goals which would reduce the costs and the weight of launching spacecraft. Charts show the engine weight distribution for both reuseable and expendable engine components. The presentation reviews the operating requirements for several components of the rocket engines. The next slide reviews the potential benefits of MMCs in general and in use as materials for Advanced Pressure Casting. The next slide reviews the drawbacks of MMCs. The reusable turbopump housing is selected to review for potential MMC application. The presentation reviews solutions for reusable turbopump materials, pointing out some of the issues. It also reviews the development of some of the materials.

  6. Aloe Vera for Tissue Engineering Applications (United States)

    Rahman, Shekh; Carter, Princeton; Bhattarai, Narayan


    Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers. PMID:28216559

  7. Aloe Vera for Tissue Engineering Applications. (United States)

    Rahman, Shekh; Carter, Princeton; Bhattarai, Narayan


    Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers.

  8. Aloe Vera for Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Shekh Rahman


    Full Text Available Aloe vera, also referred as Aloe barbadensis Miller, is a succulent plant widely used for biomedical, pharmaceutical and cosmetic applications. Aloe vera has been used for thousands of years. However, recent significant advances have been made in the development of aloe vera for tissue engineering applications. Aloe vera has received considerable attention in tissue engineering due to its biodegradability, biocompatibility, and low toxicity properties. Aloe vera has been reported to have many biologically active components. The bioactive components of aloe vera have effective antibacterial, anti-inflammatory, antioxidant, and immune-modulatory effects that promote both tissue regeneration and growth. The aloe vera plant, its bioactive components, extraction and processing, and tissue engineering prospects are reviewed in this article. The use of aloe vera as tissue engineering scaffolds, gels, and films is discussed, with a special focus on electrospun nanofibers.

  9. Microbiome engineering: Current applications and its future. (United States)

    Foo, Jee Loon; Ling, Hua; Lee, Yung Seng; Chang, Matthew Wook


    Microbiomes exist in all ecosystems and are composed of diverse microbial communities. Perturbation to microbiomes brings about undesirable phenotypes in the hosts, resulting in diseases and disorders, and disturbs the balance of the associated ecosystems. Engineering of microbiomes can be used to modify structures of the microbiota and restore ecological balance. Consequently, microbiome engineering has been employed for improving human health and agricultural productivity. The importance and current applications of microbiome engineering, particularly in humans, animals, plants and soil is reviewed. Furthermore, we explore the challenges in engineering microbiome and the future of this field, thus providing perspectives and outlook of microbiome engineering. Copyright © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Simulation Of The Internal-Combustion Engine (United States)

    Zeleznik, Frank J.; Mcbride, Bonnie J.


    Program adapts to available information about particular engine. Mathematical model of internal-combustion engine constructed and implemented as computer program suitable for use on large digital computer systems. ZMOTTO program calculates Otto-cycle performance parameters as well as working-fluid compositions and properties throughout cycle for number of consecutive cycles and for variety of input parameters. Written in standard FORTRAN IV.

  11. Collisions engineering. Theory and applications

    Energy Technology Data Exchange (ETDEWEB)

    Fremond, Michel [Rome ' ' Tor Vergata' ' Univ. (Italy). Dept. of Civil Engineering and Computer Science


    This book investigates collisions occurring in the motion of solids, in the motion of fluids but also in the motion of pedestrians in crowds. The duration of these presented collisions is short compared to the whole duration of the motion: they are assumed instantaneous. The innovative concept demonstrated in this book is that a system made of two solids, is deformable because their relative position changes. The definition of the velocities of deformation of the system introduced in the classical developments of mechanics, the principle of the virtual work and the laws of thermodynamics, allows a large range of applications such as crowd motions, debris flow motions, and shape memory alloys motions. The set of the applications is even larger: social sciences and mechanics are unified to predict the motion of crowds with application to transport management and to evacuation of theaters management.

  12. Collisions engineering theory and applications

    CERN Document Server

    Frémond, Michel


    This book investigates collisions occurring in the motion of solids, in the motion of fluids but also in the motion of pedestrians in crowds. The duration of these presented collisions is short compared to the whole duration of the motion: they are assumed instantaneous. The innovative concept demonstrated in this book is that a system made of two solids, is deformable because their relative position changes. The definition of the velocities of deformation of the system introduced in the classical developments of mechanics, the principle of the virtual work and the laws of thermodynamics, allows a large range of applications such as crowd motions, debris flow motions, and shape memory alloys motions. The set of the applications is even larger: social sciences and mechanics are unified to predict the motion of crowds with application to transport management and to evacuation of theaters management.

  13. Practical Application of Sociology in Systems Engineering (United States)

    Watson, Michael D.; Andrews, James G.; Eckley, Jeri Cassel; Culver, Michael L.


    Systems engineering involves both the integration of the system and the integration of the disciplines which develop and operate the system. Integrating the disciplines is a sociological effort to bring together different groups, who often have different terminology, to achieve a common goal, the system. The focus for the systems engineer is information flow through the organization, between the disciplines, to ensure the system is developed and operated will all relevant information informing system decisions. The practical application of the sociology in systems engineering brings in various organizational development concepts including the principles of planned renegotiation and the application of principles to address information barriers created by organizational culture. Concepts such as specification of ignorance, consistent terminology, opportunity structures, role-sets, and the reclama (reconsideration) process are all important sociological approaches that help address the organizational social structure (culture). In bringing the disciplines together, the systems engineer must also be wary of social ambivalence, social anomie, social dysfunction, and insider-outsider behavior. Unintended consequences can result when these social issues are present. These issues can occur when localized subcultures shift from the overarching organizational culture, or when the organizational culture prevents achievement of system goals. These sociological principles provide the systems engineer with key approaches to manage the information flow through the organization as the disciplines are integrated and share their information and provides key sociological barriers to information flow through the organization. This paper will discuss the practical application of sociological principles to systems engineering.

  14. The optimal homotopy asymptotic method engineering applications

    CERN Document Server

    Marinca, Vasile


    This book emphasizes in detail the applicability of the Optimal Homotopy Asymptotic Method to various engineering problems. It is a continuation of the book “Nonlinear Dynamical Systems in Engineering: Some Approximate Approaches”, published at Springer in 2011, and it contains a great amount of practical models from various fields of engineering such as classical and fluid mechanics, thermodynamics, nonlinear oscillations, electrical machines, and so on. The main structure of the book consists of 5 chapters. The first chapter is introductory while the second chapter is devoted to a short history of the development of homotopy methods, including the basic ideas of the Optimal Homotopy Asymptotic Method. The last three chapters, from Chapter 3 to Chapter 5, are introducing three distinct alternatives of the Optimal Homotopy Asymptotic Method with illustrative applications to nonlinear dynamical systems. The third chapter deals with the first alternative of our approach with two iterations. Five application...

  15. Advanced FDTD methods parallelization, acceleration, and engineering applications

    CERN Document Server

    Yu, Wenhua


    The finite-difference time-domain (FDTD) method has revolutionized antenna design and electromagnetics engineering. Here's a cutting-edge book that focuses on the performance optimization and engineering applications of FDTD simulation systems. Covering the latest developments in this area, this unique resource offer you expert advice on the FDTD method, hardware platforms, and network systems. Moreover the book offers guidance in distinguishing between the many different electromagnetics software packages on the market today. You also find a complete chapter dedicated to large multi-scale pro

  16. Modelling and Simulation of Gas Engines Using Aspen HYSYS

    Directory of Open Access Journals (Sweden)

    M. C. Ekwonu


    Full Text Available In this paper gas engine model was developed in Aspen HYSYS V7.3 and validated with Waukesha 16V275GL+ gas engine. Fuel flexibility, fuel types and part load performance of the gas engine were investigated. The design variability revealed that the gas engine can operate on poor fuel with low lower heating value (LHV such as landfill gas, sewage gas and biogas with biogas offering potential integration with bottoming cycles when compared to natural gas. The result of the gas engine simulation gave an efficiency 40.7% and power output of 3592kW.

  17. Photonics Applications and Web Engineering: WILGA 2017 (United States)

    Romaniuk, Ryszard S.


    XLth Wilga Summer 2017 Symposium on Photonics Applications and Web Engineering was held on 28 May-4 June 2017. The Symposium gathered over 350 participants, mainly young researchers active in optics, optoelectronics, photonics, modern optics, mechatronics, applied physics, electronics technologies and applications. There were presented around 300 oral and poster papers in a few main topical tracks, which are traditional for Wilga, including: bio-photonics, optical sensory networks, photonics-electronics-mechatronics co-design and integration, large functional system design and maintenance, Internet of Things, measurement systems for astronomy, high energy physics experiments, and other. The paper is a traditional introduction to the 2017 WILGA Summer Symposium Proceedings, and digests some of the Symposium chosen key presentations. This year Symposium was divided to the following topical sessions/conferences: Optics, Optoelectronics and Photonics, Computational and Artificial Intelligence, Biomedical Applications, Astronomical and High Energy Physics Experiments Applications, Material Research and Engineering, and Advanced Photonics and Electronics Applications in Research and Industry.

  18. Comparison of Engine Simulation Software for Development of Control System

    Directory of Open Access Journals (Sweden)

    KinYip Chan


    Full Text Available Most commonly used commercial engine simulation packages generate detailed estimation of the combustion and gas flow parameters. These parameters are required for advanced research on fluid flow and heat transfer and development of geometries of engine components. However, engine control involves different operating parameters. Various sensors are installed into the engine, the combustion performance is recorded, and data is sent to engine control unit (ECU. ECU computes the new set of parameters to make fine adjustments to actuators providing better engine performance. Such techniques include variable valve timing, variable ignition timing, variable air to fuel ratio, and variable compression ratio. In the present study, two of the commercial packages, Ricardo Wave and Lotus Engine Simulation, have been tested on the capabilities for engine control purposes. These packages are compared with an in-house developed package and with reference results available from the literature. Different numerical experiments have been carried out from which it can be concluded that all packages predict similar profiles of pressure and temperature in the engine cylinder. Moreover, those are in reasonable agreement with the reference results while in-house developed package is possible to run simulations with changing speed for engine control purpose.

  19. Carbon nanotubes: engineering biomedical applications. (United States)

    Gomez-Gualdrón, Diego A; Burgos, Juan C; Yu, Jiamei; Balbuena, Perla B


    Carbon nanotubes (CNTs) are cylinder-shaped allotropic forms of carbon, most widely produced under chemical vapor deposition. They possess astounding chemical, electronic, mechanical, and optical properties. Being among the most promising materials in nanotechnology, they are also likely to revolutionize medicine. Among other biomedical applications, after proper functionalization carbon nanotubes can be transformed into sophisticated biosensing and biocompatible drug-delivery systems, for specific targeting and elimination of tumor cells. This chapter provides an introduction to the chemical and electronic structure and properties of single-walled carbon nanotubes, followed by a description of the main synthesis and post-synthesis methods. These sections allow the reader to become familiar with the specific characteristics of these materials and the manner in which these properties may be dependent on the specific synthesis and post-synthesis processes. The chapter ends with a review of the current biomedical applications of carbon nanotubes, highlighting successes and challenges. Copyright © 2011 Elsevier Inc. All rights reserved.

  20. Understanding molecular simulation from algorithms to applications

    CERN Document Server

    Frenkel, Daan


    Understanding Molecular Simulation: From Algorithms to Applications explains the physics behind the ""recipes"" of molecular simulation for materials science. Computer simulators are continuously confronted with questions concerning the choice of a particular technique for a given application. A wide variety of tools exist, so the choice of technique requires a good understanding of the basic principles. More importantly, such understanding may greatly improve the efficiency of a simulation program. The implementation of simulation methods is illustrated in pseudocodes and their practic

  1. Autonomous Cryogenics Loading Operations Simulation Software: Knowledgebase Autonomous Test Engineer (United States)

    Wehner, Walter S., Jr.


    Working on the ACLO (Autonomous Cryogenics Loading Operations) project I have had the opportunity to add functionality to the physics simulation software known as KATE (Knowledgebase Autonomous Test Engineer), create a new application allowing WYSIWYG (what-you-see-is-what-you-get) creation of KATE schematic files and begin a preliminary design and implementation of a new subsystem that will provide vision services on the IHM (Integrated Health Management) bus. The functionality I added to KATE over the past few months includes a dynamic visual representation of the fluid height in a pipe based on number of gallons of fluid in the pipe and implementing the IHM bus connection within KATE. I also fixed a broken feature in the system called the Browser Display, implemented many bug fixes and made changes to the GUI (Graphical User Interface).

  2. Engineering Applications of Bird Flight (United States)


 aerofoil ...September

  3. Foam engineering fundamentals and applications

    CERN Document Server


    Containing contributions from leading academic and industrial researchers, this book provides a much needed update of foam science research. The first section of the book presents an accessible summary of the theory and fundamentals of foams. This includes chapters on morphology, drainage, Ostwald ripening, coalescence, rheology, and pneumatic foams. The second section demonstrates how this theory is used in a wide range of industrial applications, including foam fractionation, froth flotation and foam mitigation. It includes chapters on suprafroths, flotation of oil sands, foams in enhancing petroleum recovery, Gas-liquid Mass Transfer in foam, foams in glass manufacturing, fire-fighting foam technology and consumer product foams.

  4. Numerical Simulation of Methane Slip in Dual Fuel Marine Engines

    DEFF Research Database (Denmark)

    Han, Jaehyun; Jensen, Michael Vincent; Pang, Kar Mun


    and the valve timings on the methane slip was investigated. MAN L28/32DF engine was modeled to simulate the gas exchange process of the four stroke NG-diesel dual fuel engines. The mesh size of the model was decided based on the sensitivity study on the peak pressure of the cylinder and the fuel mass...

  5. Engineering Stem Cells for Biomedical Applications (United States)

    Yin, Perry T.; Han, Edward


    Stem cells are characterized by a number of useful properties, including their ability to migrate, differentiate, and secrete a variety of therapeutic molecules such as immunomodulatory factors. As such, numerous pre-clinical and clinical studies have utilized stem cell-based therapies and demonstrated their tremendous potential for the treatment of various human diseases and disorders. Recently, efforts have focused on engineering stem cells in order to further enhance their innate abilities as well as to confer them with new functionalities, which can then be used in various biomedical applications. These engineered stem cells can take on a number of forms. For instance, engineered stem cells encompass the genetic modification of stem cells as well as the use of stem cells for gene delivery, nanoparticle loading and delivery, and even small molecule drug delivery. The present Review gives an in-depth account of the current status of engineered stem cells, including potential cell sources, the most common methods used to engineer stem cells, and the utilization of engineered stem cells in various biomedical applications, with a particular focus on tissue regeneration, the treatment of immunodeficiency diseases, and cancer. PMID:25772134

  6. Mobile Applications and Multi-User Virtual Reality Simulations (United States)

    Gordillo, Orlando Enrique


    This is my third internship with NASA and my second one at the Johnson Space Center. I work within the engineering directorate in ER7 (Software Robotics and Simulations Division) at a graphics lab called IGOAL. We are a very well-rounded lab because we have dedicated software developers and dedicated 3D artist, and when you combine the two, what you get is the ability to create many different things such as interactive simulations, 3D models, animations, and mobile applications.

  7. Surface electromyography physiology, engineering and applications

    CERN Document Server

    Farina, Dario


    The book presents a quantitative approach to the study and use of noninvasively detected electromyographic (EMG) signals, as well as their numerous applications in various aspects of the life sciences. Surface Electromyography: Physiology, Engineering, and Applications is an update of Electromyography: Physiology, Engineering, and Noninvasive Applications (Wiley-IEEE Press, 2004) and focuses on the developments that have taken place over the last decade. The first nine chapters deal with the generation, detection, understanding, interpretation, and modeling of EMG signals. Detection technology, with particular focus on EMG imaging techniques that are based on two-dimensional electrode arrays are also included in the first half of the book. The latter 11 chapters deal with applications, which range fro monitoring muscle fatigue, electrically elicited contractions, posture analysis, prevention of work-related and child-delivery-related neuromuscular disorders, ergonomics, movement analysis, physical therapy, ex...

  8. Multi-agent systems simulation and applications

    CERN Document Server

    Uhrmacher, Adelinde M


    Methodological Guidelines for Modeling and Developing MAS-Based SimulationsThe intersection of agents, modeling, simulation, and application domains has been the subject of active research for over two decades. Although agents and simulation have been used effectively in a variety of application domains, much of the supporting research remains scattered in the literature, too often leaving scientists to develop multi-agent system (MAS) models and simulations from scratch. Multi-Agent Systems: Simulation and Applications provides an overdue review of the wide ranging facets of MAS simulation, i

  9. Thermal and Environmental Barrier Coatings for Advanced Turbine Engine Applications (United States)

    Zhu, Dong-Ming; Miller, Robert A.


    Ceramic thermal and environmental barrier coatings (T/EBCs) will play a crucial role in advanced gas turbine engine systems because of their ability to significantly increase engine operating temperatures and reduce cooling requirements, thus help achieve engine low emission and high efficiency goals. Advanced T/EBCs are being developed for the low emission SiC/SiC ceramic matrix composite (CMC) combustor applications by extending the CMC liner and vane temperature capability to 1650 C (3000 F) in oxidizing and water vapor containing combustion environments. Low conductivity thermal barrier coatings (TBCs) are also being developed for metallic turbine airfoil and combustor applications, providing the component temperature capability up to 1650 C (3000 F). In this paper, ceramic coating development considerations and requirements for both the ceramic and metallic components will be described for engine high temperature and high-heat-flux applications. The underlying coating failure mechanisms and life prediction approaches will be discussed based on the simulated engine tests and fracture mechanics modeling results.

  10. Electromyography physiology engineering and noninvasive applications

    CERN Document Server

    Parker, Philip; John Wiley & Sons


    "Featuring contributions from key innovators working in the field today, Electromyography reveals the broad applications of EMG data in areas as diverse as neurology, ergonomics, exercise physiology, rehabilitation, movement analysis, biofeedback, and myoelectric control of prostheses." "Electromyography offers physiologists, medical professionals, and students in biomedical engineering a new window into the possibilities of this technology."--Jacket.

  11. SDM applications to machine tools and engines

    Indian Academy of Sciences (India)

    The method of structural dynamic optimization is applied here to two real-life structures, a small two-cylinder, air-cooled gasoline engine and a high speed machine tool. The aim of the first application isthe reduction of the kinematic vibration transmission path composed of a piston-connecting rod, a crankshaft and an ...

  12. Experiences on dynamic simulation software in chemical engineering education

    DEFF Research Database (Denmark)

    Komulainen, Tiina M.; Enemark-rasmussen, Rasmus; Sin, Gürkan


    : basic chemical engineering, operability and safety analysis and process control. User experiences from both teachers and students are presented. The benefits of dynamic simulation as an additional teaching tool are discussed and summarized. The experiences confirm that commercial dynamic simulators...... provide realistic training and can be successfully integrated into undergraduate and graduate teaching, laboratory courses and research....

  13. Expert System Architecture for Rocket Engine Numerical Simulators: A Vision (United States)

    Mitra, D.; Babu, U.; Earla, A. K.; Hemminger, Joseph A.


    Simulation of any complex physical system like rocket engines involves modeling the behavior of their different components using mostly numerical equations. Typically a simulation package would contain a set of subroutines for these modeling purposes and some other ones for supporting jobs. A user would create an input file configuring a system (part or whole of a rocket engine to be simulated) in appropriate format understandable by the package and run it to create an executable module corresponding to the simulated system. This module would then be run on a given set of input parameters in another file. Simulation jobs are mostly done for performance measurements of a designed system, but could be utilized for failure analysis or a design job such as inverse problems. In order to use any such package the user needs to understand and learn a lot about the software architecture of the package, apart from being knowledgeable in the target domain. We are currently involved in a project in designing an intelligent executive module for the rocket engine simulation packages, which would free any user from this burden of acquiring knowledge on a particular software system. The extended abstract presented here will describe the vision, methodology and the problems encountered in the project. We are employing object-oriented technology in designing the executive module. The problem is connected to the areas like the reverse engineering of any simulation software, and the intelligent systems for simulation.

  14. Numerical Simulation of Methane Slip in Dual Fuel Marine Engines

    DEFF Research Database (Denmark)

    Han, Jaehyun; Jensen, Michael Vincent; Pang, Kar Mun

    and the valve timings on the methane slip was investigated. MAN L28/32DF engine was modeled to simulate the gas exchange process of the four stroke NG-diesel dual fuel engines. The mesh size of the model was decided based on the sensitivity study on the peak pressure of the cylinder and the fuel mass......The methane slip is the problematic issue for the engines using natural gas(NG). Because methane is more powerful greenhouse gas (GHG) than CO2, understanding of the methane slip during gas exchange process of the engines is essential. In this study, the influence of the gas pipe geometry...

  15. An Object Model for a Rocket Engine Numerical Simulator (United States)

    Mitra, D.; Bhalla, P. N.; Pratap, V.; Reddy, P.


    Rocket Engine Numerical Simulator (RENS) is a packet of software which numerically simulates the behavior of a rocket engine. Different parameters of the components of an engine is the input to these programs. Depending on these given parameters the programs output the behaviors of those components. These behavioral values are then used to guide the design of or to diagnose a model of a rocket engine "built" by a composition of these programs simulating different components of the engine system. In order to use this software package effectively one needs to have a flexible model of a rocket engine. These programs simulating different components then should be plugged into this modular representation. Our project is to develop an object based model of such an engine system. We are following an iterative and incremental approach in developing the model, as is the standard practice in the area of object oriented design and analysis of softwares. This process involves three stages: object modeling to represent the components and sub-components of a rocket engine, dynamic modeling to capture the temporal and behavioral aspects of the system, and functional modeling to represent the transformational aspects. This article reports on the first phase of our activity under a grant (RENS) from the NASA Lewis Research center. We have utilized Rambaugh's object modeling technique and the tool UML for this purpose. The classes of a rocket engine propulsion system are developed and some of them are presented in this report. The next step, developing a dynamic model for RENS, is also touched upon here. In this paper we will also discuss the advantages of using object-based modeling for developing this type of an integrated simulator over other tools like an expert systems shell or a procedural language, e.g., FORTRAN. Attempts have been made in the past to use such techniques.

  16. Improved automated diagnosis of misfire in internal combustion engines based on simulation models (United States)

    Chen, Jian; Bond Randall, Robert


    In this paper, a new advance in the application of Artificial Neural Networks (ANNs) to the automated diagnosis of misfires in Internal Combustion engines(IC engines) is detailed. The automated diagnostic system comprises three stages: fault detection, fault localization and fault severity identification. Particularly, in the severity identification stage, separate Multi-Layer Perceptron networks (MLPs) with saturating linear transfer functions were designed for individual speed conditions, so they could achieve finer classification. In order to obtain sufficient data for the network training, numerical simulation was used to simulate different ranges of misfires in the engine. The simulation models need to be updated and evaluated using experimental data, so a series of experiments were first carried out on the engine test rig to capture the vibration signals for both normal condition and with a range of misfires. Two methods were used for the misfire diagnosis: one is based on the torsional vibration signals of the crankshaft and the other on the angular acceleration signals (rotational motion) of the engine block. Following the signal processing of the experimental and simulation signals, the best features were selected as the inputs to ANN networks. The ANN systems were trained using only the simulated data and tested using real experimental cases, indicating that the simulation model can be used for a wider range of faults for which it can still be considered valid. The final results have shown that the diagnostic system based on simulation can efficiently diagnose misfire, including location and severity.

  17. Practical applications of soft computing in engineering

    CERN Document Server


    Soft computing has been presented not only with the theoretical developments but also with a large variety of realistic applications to consumer products and industrial systems. Application of soft computing has provided the opportunity to integrate human-like vagueness and real-life uncertainty into an otherwise hard computer program. This book highlights some of the recent developments in practical applications of soft computing in engineering problems. All the chapters have been sophisticatedly designed and revised by international experts to achieve wide but in-depth coverage. Contents: Au

  18. Multiscale-multiphysics approaches for engineering applications (United States)

    Pozzetti, Gabriele; Peters, Bernhard


    Engineering applications often require the study of complex Multiphysics systems. In order to provide solutions for problems of industrial-environmental interest, methods that can capture the influence of all the different scales of composite phenomena must be developed. Due to these necessities multiscale and multiphysics approaches are rapidly becoming a standard in the mathematical-numerical description of engineering systems. The goal of the symposium is to bring together industrial and environmental researcher and practitioners, in order to discuss techniques that aim to solve this kind of heterogeneous problem in an highly efficient way.

  19. XVI 'Jacques-Louis Lions' Spanish-French School on Numerical Simulation in Physics and Engineering

    CERN Document Server

    Roldán, Teo; Torrens, Juan


    This book presents lecture notes from the XVI ‘Jacques-Louis Lions’ Spanish-French School on Numerical Simulation in Physics and Engineering, held in Pamplona (Navarra, Spain) in September 2014. The subjects covered include: numerical analysis of isogeometric methods, convolution quadrature for wave simulations, mathematical methods in image processing and computer vision, modeling and optimization techniques in food processes, bio-processes and bio-systems, and GPU computing for numerical simulation. The book is highly recommended to graduate students in Engineering or Science who want to focus on numerical simulation, either as a research topic or in the field of industrial applications. It can also benefit senior researchers and technicians working in industry who are interested in the use of state-of-the-art numerical techniques in the fields addressed here. Moreover, the book can be used as a textbook for master courses in Mathematics, Physics, or Engineering.

  20. Simulation based engineering in fluid flow design

    CERN Document Server

    Rao, J S


    This volume offers a tool for High Performance Computing (HPC). A brief historical background on the subject is first given. Fluid Statics dealing with Pressure in fluids at rest, Buoyancy and Basics of Thermodynamics are next presented. The Finite Volume Method, the most convenient process for HPC, is explained in one-dimensional approach to diffusion with convection and pressure velocity coupling. Adiabatic, isentropic and supersonic flows in quasi-one dimensional flows in axisymmetric nozzles is considered before applying CFD solutions. Though the theory is restricted to one-dimensional cases, three-dimensional CFD examples are also given. Lastly, nozzle flows with normal shocks are presented using turbulence models. Worked examples and exercises are given in each chapter. Fluids transport thermal energy for its conversion to kinetic energy, thus playing a major role that is central to all heat engines. With the advent of rotating machinery in the 20th century, Fluid Engineering was developed in the form o...

  1. Simulation Based Studies in Software Engineering: A Matter of Validity

    Directory of Open Access Journals (Sweden)

    Breno Bernard Nicolau de França


    Full Text Available Despite the possible lack of validity when compared with other science areas, Simulation-Based Studies (SBS in Software Engineering (SE have supported the achievement of some results in the field. However, as it happens with any other sort of experimental study, it is important to identify and deal with threats to validity aiming at increasing their strength and reinforcing results confidence. OBJECTIVE: To identify potential threats to SBS validity in SE and suggest ways to mitigate them. METHOD: To apply qualitative analysis in a dataset resulted from the aggregation of data from a quasi-systematic literature review combined with ad-hoc surveyed information regarding other science areas. RESULTS: The analysis of data extracted from 15 technical papers allowed the identification and classification of 28 different threats to validity concerned with SBS in SE according Cook and Campbell’s categories. Besides, 12 verification and validation procedures applicable to SBS were also analyzed and organized due to their ability to detect these threats to validity. These results were used to make available an improved set of guidelines regarding the planning and reporting of SBS in SE. CONCLUSIONS: Simulation based studies add different threats to validity when compared with traditional studies. They are not well observed and therefore, it is not easy to identify and mitigate all of them without explicit guidance, as the one depicted in this paper.

  2. Electro-Quasistatic Simulations in Bio-Systems Engineering and Medical Engineering

    Directory of Open Access Journals (Sweden)

    U. van Rienen


    Full Text Available Slowly varying electromagnetic fields play a key role in various applications in bio-systems and medical engineering. Examples are the electric activity of neurons on neurochips used as biosensors, the stimulating electric fields of implanted electrodes used for deep brain stimulation in patients with Morbus Parkinson and the stimulation of the auditory nerves in deaf patients, respectively. In order to simulate the neuronal activity on a chip it is necessary to couple Maxwell's and Hodgkin-Huxley's equations. First numerical results for a neuron coupling to a single electrode are presented. They show a promising qualitative agreement with the experimentally recorded signals. Further, simulations are presented on electrodes for deep brain stimulation in animal experiments where the question of electrode ageing and energy deposition in the surrounding tissue are of major interest. As a last example, electric simulations for a simple cochlea model are presented comparing the field in the skull bones for different electrode types and stimulations in different positions.

  3. Towards an Automated Full-Turbofan Engine Numerical Simulation (United States)

    Reed, John A.; Turner, Mark G.; Norris, Andrew; Veres, Joseph P.


    The objective of this study was to demonstrate the high-fidelity numerical simulation of a modern high-bypass turbofan engine. The simulation utilizes the Numerical Propulsion System Simulation (NPSS) thermodynamic cycle modeling system coupled to a high-fidelity full-engine model represented by a set of coupled three-dimensional computational fluid dynamic (CFD) component models. Boundary conditions from the balanced, steady-state cycle model are used to define component boundary conditions in the full-engine model. Operating characteristics of the three-dimensional component models are integrated into the cycle model via partial performance maps generated automatically from the CFD flow solutions using one-dimensional meanline turbomachinery programs. This paper reports on the progress made towards the full-engine simulation of the GE90-94B engine, highlighting the generation of the high-pressure compressor partial performance map. The ongoing work will provide a system to evaluate the steady and unsteady aerodynamic and mechanical interactions between engine components at design and off-design operating conditions.

  4. Engineered cell manipulation for biomedical application

    CERN Document Server

    Akashi, Misturu; Matsusaki, Michiya


    This book is the first to summarize new technologies for engineered cell manipulation. The contents focus on control of cellular functions by nanomaterials and control of three-dimensional cell-cell interactions. Control of cellular functions is important for cell differentiation, maturation, and activation, which generally are controlled by the addition of soluble cytokines or growth factors into cell culture dishes. Target antigen molecules can be efficiently delivered to the cytosol of the dendritic cells using the nanoparticle technique described here, and cellular functions such as dendritic cell maturation can be controlled easily and with precision. This book describes basic preparation of the nanoparticles, activation control of dendritic cells, immune function control, and in vivo application for various vaccination systems. The second type of control,that of cell-cell interaction, is important for tissue engineering in order to develop three-dimensional cellular constructs. To achieve in vitro engin...

  5. Development of an engine system simulation software package - ESIM

    Energy Technology Data Exchange (ETDEWEB)

    Erlandsson, Olof


    A software package, ESIM is developed for simulating internal combustion engine systems, including models for engine, manifolds, turbocharger, charge-air cooler (inter cooler) and inlet air heater. This study focus on the thermodynamic treatment and methods used in the models. It also includes some examples of system simulations made with these models for validation purposes. The engine model can be classified as a zero-dimensional, single zone model. It includes calculation of the valve flow process, models for heat release and models for in-cylinder, exhaust port and manifold heat transfer. Models are developed for handling turbocharger performance and charge air cooler characteristics. The main purpose of the project related to this work is to use the ESIM software to study heat balance and performance of homogeneous charge compression ignition (HCCI) engine systems. A short description of the HCCI engine is therefore included, pointing out the difficulties, or challenges regarding the HCCI engine, from a system perspective. However, the relations given here, and the code itself, is quite general, making it possible to use these models to simulate spark ignited, as well as direct injected engines.

  6. Engineered Proteins: Redox Properties and Their Applications (United States)

    Prabhulkar, Shradha; Tian, Hui; Wang, Xiaotang; Zhu, Jun-Jie


    Abstract Oxidoreductases and metalloproteins, representing more than one third of all known proteins, serve as significant catalysts for numerous biological processes that involve electron transfers such as photosynthesis, respiration, metabolism, and molecular signaling. The functional properties of the oxidoreductases/metalloproteins are determined by the nature of their redox centers. Protein engineering is a powerful approach that is used to incorporate biological and abiological redox cofactors as well as novel enzymes and redox proteins with predictable structures and desirable functions for important biological and chemical applications. The methods of protein engineering, mainly rational design, directed evolution, protein surface modifications, and domain shuffling, have allowed the creation and study of a number of redox proteins. This review presents a selection of engineered redox proteins achieved through these methods, resulting in a manipulation in redox potentials, an increase in electron-transfer efficiency, and an expansion of native proteins by de novo design. Such engineered/modified redox proteins with desired properties have led to a broad spectrum of practical applications, ranging from biosensors, biofuel cells, to pharmaceuticals and hybrid catalysis. Glucose biosensors are one of the most successful products in enzyme electrochemistry, with reconstituted glucose oxidase achieving effective electrical communication with the sensor electrode; direct electron-transfer-type biofuel cells are developed to avoid thermodynamic loss and mediator leakage; and fusion proteins of P450s and redox partners make the biocatalytic generation of drug metabolites possible. In summary, this review includes the properties and applications of the engineered redox proteins as well as their significance and great potential in the exploration of bioelectrochemical sensing devices. Antioxid. Redox Signal. 17, 1796–1822. PMID:22435347

  7. Application of Formal Methods in Software Engineering

    Directory of Open Access Journals (Sweden)

    Adriana Morales


    Full Text Available The purpose of this research work is to examine: (1 why are necessary the formal methods for software systems today, (2 high integrity systems through the methodology C-by-C –Correctness-by-Construction–, and (3 an affordable methodology to apply formal methods in software engineering. The research process included reviews of the literature through Internet, in publications and presentations in events. Among the Research results found that: (1 there is increasing the dependence that the nations have, the companies and people of software systems, (2 there is growing demand for software Engineering to increase social trust in the software systems, (3 exist methodologies, as C-by-C, that can provide that level of trust, (4 Formal Methods constitute a principle of computer science that can be applied software engineering to perform reliable process in software development, (5 software users have the responsibility to demand reliable software products, and (6 software engineers have the responsibility to develop reliable software products. Furthermore, it is concluded that: (1 it takes more research to identify and analyze other methodologies and tools that provide process to apply the Formal Software Engineering methods, (2 Formal Methods provide an unprecedented ability to increase the trust in the exactitude of the software products and (3 by development of new methodologies and tools is being achieved costs are not more a disadvantage for application of formal methods.

  8. Simulation Optimization for Transportation System: A Real Case Application

    Directory of Open Access Journals (Sweden)

    Muhammet Enes Akpınar


    Full Text Available Simulation applications help decision makers to give right decisions to eliminate some problems such as: create a new firm, need some changes inside a factory; improve the process of a hospital etc. In this engineering simulation study, there are two points which are used by students to arrive at the University. Initial point is the train station and the final point is the arrival point. Students’ transportation is provided with buses. The main problem is to decide the number of buses by taking number of student into consideration. To be able to solve this real-life application PROMODEL pack software is used.

  9. Real-Time Engineering Simulation of Lunar Excavation

    Energy Technology Data Exchange (ETDEWEB)

    Bruce Damer, George Tompkins, Sheldon Freid, Dave Rasmussen, Peter Newman, Brad Blair


    DigitalSpace Corporation has been building an open source real-time three-dimensional (3-D) collaborative design engineering and training platform called Digital Spaces (DSS) in support of the Exploration Vision of the National Aeronautics and Space Administration (NASA). Real-time 3-D simulation has reached a level of maturity where it is capable of supporting engineering design and operations using off-the-shelf game chipsets and open source physics and rendering technologies. This paper will illustrate a state-of-the-art real-time engineering simulation utilizing DSS in support of NASA lunar excavation studies. During the project DigitalSpace building driveable 3-D models of lunar excavators and South Polar terrain, and added a soil mechanics physics model as well as a random failure generator to the repertoire of standard mobility platform physics in prior use for real-time engineering and operational analysis at NASA.

  10. Engineering report for simulated riser installation

    Energy Technology Data Exchange (ETDEWEB)

    Brevick, C.H., Westinghouse Hanford


    The simulated riser installation field tests demonstrated that new access ports (risers) can be installed safely, quickly, and economically in the concrete domes of existing underground single- shell waste storage tanks by utilizing proven rotary drilling equipment and vacuum excavation techniques. The new riser installation will seal against water intrusion, provide as table riser anchored to the tank dome, and be installed in accordance with ALARA principles. The information contained in the report will apply to actual riser installation activity in the future.

  11. Heat transfer applications for the practicing engineer

    CERN Document Server

    Theodore, Louis


    This book serves as a training tool for individuals in industry and academia involved with heat transfer applications. Although the literature is inundated with texts emphasizing theory and theoretical derivations, the goal of this book is to present the subject of heat transfer from a strictly pragmatic point of view. The book is divided into four Parts: Introduction, Principles, Equipment Design Procedures and Applications, and ABET-related Topics. The first Part provides a series of chapters concerned with introductory topics that are required when solving most engineering problems, inclu

  12. Automated Comparison of Building Energy Simulation Engines (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Polly, B.; Horowitz, S.; Booten, B.; Kruis, N.; Christensen, C.


    This presentation describes the BEopt comparative test suite, which is a tool that facilitates the automated comparison of building energy simulation engines. It also demonstrates how the test suite is improving the accuracy of building energy simulation programs. Building energy simulation programs inform energy efficient design for new homes and energy efficient upgrades for existing homes. Stakeholders rely on accurate predictions from simulation programs. Previous research indicates that software tends to over-predict energy usage for poorly-insulated leaky homes. NREL is identifying, investigating, and resolving software inaccuracy issues. Comparative software testing is one method of many that NREL uses to identify potential software issues.

  13. A parallel framework for multidisciplinary aerospace engineering simulations using unstructured meshes (United States)

    Morgan, K.; Weatherill, N. P.; Hassan, O.; Brookes, P. J.; Said, R.; Jones, J.


    High performance parallel computers offer the promise of sufficient computational power to enable the routine use of large scale simulations during the process of engineering design. With this in mind, and with particular reference to the aerospace industry, this paper describes developments that have been undertaken to provide parallel implementations of algorithms for simulation, mesh generation and visualization. Designers are also demanding that software should be easy to use and, here, this requirement is addressed by embedding the algorithms within a convenient computer environment. This environment allows for the integration of arbitrary application software, which enables the development of a multidisciplinary engineering analysis capability within a unified computational framework. Copyright

  14. Autonomic Computing Paradigm For Large Scale Scientific And Engineering Applications (United States)

    Hariri, S.; Yang, J.; Zhang, Y.


    Large-scale distributed scientific applications are highly adaptive and heterogeneous in terms of their computational requirements. The computational complexity associated with each computational region or domain varies continuously and dramatically both in space and time throughout the whole life cycle of the application execution. Furthermore, the underlying distributed computing environment is similarly complex and dynamic in the availabilities and capacities of the computing resources. These challenges combined together make the current paradigms, which are based on passive components and static compositions, ineffectual. Autonomic Computing paradigm is an approach that efficiently addresses the complexity and dynamism of large scale scientific and engineering applications and realizes the self-management of these applications. In this presentation, we present an Autonomic Runtime Manager (ARM) that supports the development of autonomic applications. The ARM includes two modules: online monitoring and analysis module and autonomic planning and scheduling module. The ARM behaves as a closed-loop control system that dynamically controls and manages the execution of the applications at runtime. It regularly senses the state changes of both the applications and the underlying computing resources. It then uses these runtime information and prior knowledge about the application behavior and its physics to identify the appropriate solution methods as well as the required computing and storage resources. Consequently this approach enables us to develop autonomic applications, which are capable of self-management and self-optimization. We have developed and implemented the autonomic computing paradigms for several large scale applications such as wild fire simulations, simulations of flow through variably saturated geologic formations, and life sciences. The distributed wildfire simulation models the wildfire spread behavior by considering such factors as fuel

  15. Numerical simulation of spark ignition engine using OpenFOAM®

    Directory of Open Access Journals (Sweden)

    B.T. Kannan


    Full Text Available The present work is the numerical investigation of Spark Ignition (SI engines using an open source Computational Fluid Dynamics (CFD tool. Investigations on the usage of OpenFOAM® CFD tool has been carried out for the simulation of SI engines using engineFoam solver. Four-valve pent roof type engine is chosen for the present simulations. The standard k–ɛ turbulence model is used along with the Reynolds Averaged Navier Stokes (RANS equations for simulating the flow field. Energy equation and transport equation for regress variable is solved along with the momentum equations. Xi model is used for the transport and Gulder's correlation is used for laminar flame speed. Unstrained model is used for calculating the laminar flame speed velocity. Two simulations are carried out one with cold flow and the other with combustion. For combustion analysis, Iso-octane fuel is used. Average cylinder pressure is tracked for different Crank Angles (CA from −180 to 60. The temperature contours are plotted on a vertical plane inside the cylinder to indicate the rise in temperature due to combustion. The results indicate that the open source CFD code can be an ideal choice for engine designers.

  16. Exergetic analysis of cogeneration plants through integration of internal combustion engine and process simulators

    Energy Technology Data Exchange (ETDEWEB)

    Carvalho, Leonardo de Oliveira [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)], E-mail:; Leiroz, Albino Kalab; Cruz, Manuel Ernani [Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE/UFRJ), RJ (Brazil). Programa de Engenharia Mecanica], Emails:,


    Internal combustion engines (ICEs) have been used in industry and power generation much before they were massively employed for transportation. Their high reliability, excellent power-to-weight ratio, and thermal efficiency have made them a competitive choice as main energy converters in small to medium sized power plants. Process simulators can model ICE powered energy plants with limited depth, due to the highly simplified ICE models used. Usually a better understanding of the global effects of different engine parameters is desirable, since the combustion process within the ICE is typically the main cause of exergy destruction in systems which utilize them. Dedicated commercial ICE simulators have reached such a degree of maturity, that they can adequately model a wide spectrum of phenomena that occur in ICEs. However, ICE simulators are unable to incorporate the remaining of power plant equipment and processes in their models. This paper presents and exploits the integration of an internal combustion engine simulator with a process simulator, so as to evaluate the construction of a fully coupled simulation platform to analyze the performance of ICE-based power plants. A simulation model of an actual cogeneration plant is used as a vehicle for application of the proposed computational methodology. The results show that by manipulating the engine mapping parameters, the overall efficiency of the plant can be improved. (author)

  17. Systems Engineering Model and Training Application for Desktop Environment (United States)

    May, Jeffrey T.


    Provide a graphical user interface based simulator for desktop training, operations and procedure development and system reference. This simulator allows for engineers to train and further understand the dynamics of their system from their local desktops. It allows the users to train and evaluate their system at a pace and skill level based on the user's competency and from a perspective based on the user's need. The simulator will not require any special resources to execute and should generally be available for use. The interface is based on a concept of presenting the model of the system in ways that best suits the user's application or training needs. The three levels of views are Component View, the System View (overall system), and the Console View (monitor). These views are portals into a single model, so changing the model from one view or from a model manager Graphical User Interface will be reflected on all other views.

  18. NTP system simulation and detailed nuclear engine modeling (United States)

    Anghaie, Samim


    The topics are presented in viewgraph form and include the following: nuclear thermal propulsion (NTP) & detailed nuclear engine modeling; modeling and engineering simulation of nuclear thermal rocket systems; nuclear thermal rocket simulation system; INSPI-NTVR core axial flow profiles; INSPI-NTRV core axial flow profiles; specific impulse vs. chamber pressure; turbine pressure ratio vs. chamber pressure; NERVA core axial flow profiles; P&W XNR2000 core axial flow profiles; pump pressure rise vs. chamber pressure; streamline of jet-induced flow in cylindrical chamber; flow pattern of a jet-induced flow in a chamber; and radiative heat transfer models.

  19. CNC Milling Machine Simulation in Engineering Education


    Lo Valvo, E; Licari, R; Adornetto, A


    In this work an effective simulator for a CNC milling machine is presented. It has been developed in EMC2, a free Opens Source NC software running in Linux environment, developed by an international community. It can be installed on a common PC and is able to: control a CNC machine; read part programs; display the tool path; send instructions to the CNC machine for the cutting process. In this work a new feature has been implemented, which can both display a 3D model of the machine and simula...

  20. Speeding up predictive electromagnetic simulations for ITER application

    Energy Technology Data Exchange (ETDEWEB)

    Alekseev, A.B. [ITER Organization, Route de Vinon sur Verdon, 13067 St. Paul Lez Durance Cedex (France); Amoskov, V.M. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); Bazarov, A.M., E-mail: [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); Belov, A.V. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); Belyakov, V.A. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); St. Petersburg State University, 7/9 Universitetskaya Embankment, St. Petersburg, 199034 (Russian Federation); Gapionok, E.I. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); Gornikel, I.V. [Alphysica GmbH, Unterreut, 6, D-76135, Karlsruhe (Germany); Gribov, Yu. V. [ITER Organization, Route de Vinon sur Verdon, 13067 St. Paul Lez Durance Cedex (France); Kukhtin, V.P.; Lamzin, E.A. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); Sytchevsky, S.E. [JSC “NIIEFA”, Doroga na Metallostroy 3, St. Petersburg, 196641 (Russian Federation); St. Petersburg State University, 7/9 Universitetskaya Embankment, St. Petersburg, 199034 (Russian Federation)


    Highlights: • A general concept of engineering EM simulator for tokamak application is proposed. • An algorithm is based on influence functions and superposition principle. • The software works with extensive databases and offers parallel processing. • The simulator allows us to obtain the solution hundreds times faster. - Abstract: The paper presents an attempt to proceed to a general concept of software environment for fast and consistent multi-task simulation of EM transients (engineering simulator for tokamak applications). As an example, the ITER tokamak is taken to introduce a computational technique. The strategy exploits parallel processing with optimized simulation algorithms based on using of influence functions and superposition principle to take full advantage of parallelism. The software has been tested on a multi-core supercomputer. The results were compared with data obtained in TYPHOON computations. A discrepancy was found to be below 0.4%. The computation cost for the simulator is proportional to the number of observation points. An average computation time with the simulator is found to be by hundreds times less than the time required to solve numerically a relevant system of differential equations for known software tools.

  1. Engineering models for merging wakes in wind farm optimization applications

    DEFF Research Database (Denmark)

    Machefaux, Ewan; Larsen, Gunner Chr.; Murcia Leon, Juan Pablo


    The present paper deals with validation of 4 different engineering wake superposition approaches against detailed CFD simulations and covering different turbine interspacing, ambient turbulence intensities and mean wind speeds. The first engineering model is a simple linear superposition of wake ...

  2. Advances in Intelligent Modelling and Simulation Simulation Tools and Applications

    CERN Document Server

    Oplatková, Zuzana; Carvalho, Marco; Kisiel-Dorohinicki, Marek


    The human capacity to abstract complex systems and phenomena into simplified models has played a critical role in the rapid evolution of our modern industrial processes and scientific research. As a science and an art, Modelling and Simulation have been one of the core enablers of this remarkable human trace, and have become a topic of great importance for researchers and practitioners. This book was created to compile some of the most recent concepts, advances, challenges and ideas associated with Intelligent Modelling and Simulation frameworks, tools and applications. The first chapter discusses the important aspects of a human interaction and the correct interpretation of results during simulations. The second chapter gets to the heart of the analysis of entrepreneurship by means of agent-based modelling and simulations. The following three chapters bring together the central theme of simulation frameworks, first describing an agent-based simulation framework, then a simulator for electrical machines, and...

  3. Electrospun polyurethane membranes for Tissue Engineering applications. (United States)

    Gabriel, Laís P; Rodrigues, Ana Amélia; Macedo, Milton; Jardini, André L; Maciel Filho, Rubens


    Tissue Engineering proposes, among other things, tissue regeneration using scaffolds integrated with biological molecules, growth factors or cells for such regeneration. In this research, polyurethane membranes were prepared using the electrospinning technique in order to obtain membranes to be applied in Tissue Engineering, such as epithelial, drug delivery or cardiac applications. The influence of fibers on the structure and morphology of the membranes was studied using scanning electron microscopy (SEM), the structure was evaluated by Fourier transform infrared spectroscopy (FT-IR), and the thermal stability was analyzed by thermogravimetry analysis (TGA). In vitro cells attachment and proliferation was investigated by SEM, and in vitro cell viability was studied by 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assays and Live/Dead® assays. It was found that the membranes present an homogeneous morphology, high porosity, high surface area/volume ratio, it was also observed a random fiber network. The thermal analysis showed that the membrane degradation started at 254°C. In vitro evaluation of fibroblasts cells showed that fibroblasts spread over the membrane surface after 24, 48 and 72h of culture. This study supports the investigation of electrospun polyurethane membranes as biocompatible scaffolds for Tissue Engineering applications and provides some guidelines for improved biomaterials with desired properties. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Mean Line Pump Flow Model in Rocket Engine System Simulation (United States)

    Veres, Joseph P.; Lavelle, Thomas M.


    A mean line pump flow modeling method has been developed to provide a fast capability for modeling turbopumps of rocket engines. Based on this method, a mean line pump flow code PUMPA has been written that can predict the performance of pumps at off-design operating conditions, given the loss of the diffusion system at the design point. The pump code can model axial flow inducers, mixed-flow and centrifugal pumps. The code can model multistage pumps in series. The code features rapid input setup and computer run time, and is an effective analysis and conceptual design tool. The map generation capability of the code provides the map information needed for interfacing with a rocket engine system modeling code. The off-design and multistage modeling capabilities of the code permit parametric design space exploration of candidate pump configurations and provide pump performance data for engine system evaluation. The PUMPA code has been integrated with the Numerical Propulsion System Simulation (NPSS) code and an expander rocket engine system has been simulated. The mean line pump flow code runs as an integral part of the NPSS rocket engine system simulation and provides key pump performance information directly to the system model at all operating conditions.

  5. Simulation systems: design and applications

    Directory of Open Access Journals (Sweden)

    Liudmila Burtseva


    Full Text Available In this paper the history of Simulation System Group investigations is presented. Some important achievements in past and present time are marked. The directions of future investigations are discussed in the fourth section of the paper.

  6. Improving a Computer Networks Course Using the Partov Simulation Engine (United States)

    Momeni, B.; Kharrazi, M.


    Computer networks courses are hard to teach as there are many details in the protocols and techniques involved that are difficult to grasp. Employing programming assignments as part of the course helps students to obtain a better understanding and gain further insight into the theoretical lectures. In this paper, the Partov simulation engine and…

  7. Real-time Simulation of Turboprop Engine Control System (United States)

    Sheng, Hanlin; Zhang, Tianhong; Zhang, Yi


    On account of the complexity of turboprop engine control system, real-time simulation is the technology, under the prerequisite of maintaining real-time, to effectively reduce development cost, shorten development cycle and avert testing risks. The paper takes RT-LAB as a platform and studies the real-time digital simulation of turboprop engine control system. The architecture, work principles and external interfaces of RT-LAB real-time simulation platform are introduced firstly. Then based on a turboprop engine model, the control laws of propeller control loop and fuel control loop are studied. From that and on the basis of Matlab/Simulink, an integrated controller is designed which can realize the entire process control of the engine from start-up to maximum power till stop. At the end, on the basis of RT-LAB platform, the real-time digital simulation of the designed control system is studied, different regulating plans are tried and more ideal control effects have been obtained.

  8. Analysis of simulated engine sounds using a psychoacoustic model (United States)

    Duvigneau, Fabian; Liefold, Steffen; Höchstetter, Marius; Verhey, Jesko L.; Gabbert, Ulrich


    The aim of the paper is the evaluation and the prediction of the perceived quality of engine sounds, which is predicted in the design process by numerical simulations. Periodic combustion sounds of the operating engine are synthesized with the help of an overall numerical simulation approach before a real prototype exists. The perceived quality of the sound is rated in hearing tests using the method of relative comparison and absolute judgment. Results are transferred into an interval scaled ranking of the stimuli. Based on the data, a psychoacoustic model for sound quality is developed using psychoacoustic parameters. Predictions of this model are used to evaluate the sound quality of several technical design modifications, for example, different engine encapsulations. The results are visualized to allow a simple qualitative analysis of the sound perception. This results in an impartial and objective decision regarding the final design of an acoustic encapsulation with a higher perceived sound quality.

  9. Engineering growth factors for regenerative medicine applications.

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, Aaron C.; Briquez, Priscilla S.; Hubbell, Jeffrey A.; Cochran, Jennifer R.


    Growth factors are important morphogenetic proteins that instruct cell behavior and guide tissue repair and renewal. Although their therapeutic potential holds great promise in regenerative medicine applications, translation of growth factors into clinical treatments has been hindered by limitations including poor protein stability, low recombinant expression yield, and suboptimal efficacy. This review highlights current tools, technologies, and approaches to design integrated and effective growth factor-based therapies for regenerative medicine applications. The first section describes rational and combinatorial protein engineering approaches that have been utilized to improve growth factor stability, expression yield, biodistribution, and serum half-life, or alter their cell trafficking behavior or receptor binding affinity. The second section highlights elegant biomaterial-based systems, inspired by the natural extracellular matrix milieu, that have been developed for effective spatial and temporal delivery of growth factors to cell surface receptors. Although appearing distinct, these two approaches are highly complementary and involve principles of molecular design and engineering to be considered in parallel when developing optimal materials for clinical applications.

  10. ATLAS Tracking Detector Upgrade studies using the Fast Simulation Engine

    CERN Document Server

    Calace, Noemi; The ATLAS collaboration


    The successful physics program Run-1 of the LHC has put a strong emphasis on design studies for future upgrades of the existing LHC detectors. In ATLAS, testing alternative layouts through the full simulation and reconstruction chain is a work-intensive program, which can only be carried out for a few concept layouts. To facilitate layout prototyping, we have established a novel technique based on the ATLAS reconstruction geometry and a fast simulation engine that allows fast layout iterations and a realistic but fast Monte Carlo simulation. This approach is extended by a fast digitisation and reconstruction module.

  11. Comparison of Engineering Wake Models with CFD Simulations

    DEFF Research Database (Denmark)

    Andersen, Søren Juhl; Sørensen, Jens Nørkær; Ivanell, S.


    The engineering wake models by Jensen [1] and Frandsen et al. [2] are assessed for different scenarios simulated using Large Eddy Simulation and the Actuator Line method implemented in the Navier-Stokes equations. The scenarios include the far wake behind a single wind turbine, a long row...... of turbines in an atmospheric boundary layer, idealised cases of an infinitely long row of wind turbines and infinite wind farms with three different spacings. Both models include a wake expansion factor, which is calibrated to fit the simulated wake velocities. The analysis highlights physical deficiencies...

  12. Computer- Aided Design in Power Engineering Application of Software Tools

    CERN Document Server

    Stojkovic, Zlatan


    This textbooks demonstrates the application of software tools in solving a series of problems from the field of designing power system structures and systems. It contains four chapters: The first chapter leads the reader through all the phases necessary in the procedures of computer aided modeling and simulation. It guides through the complex problems presenting on the basis of eleven original examples. The second chapter presents  application of software tools in power system calculations of power systems equipment design. Several design example calculations are carried out using engineering standards like MATLAB, EMTP/ATP, Excel & Access, AutoCAD and Simulink. The third chapters focuses on the graphical documentation using a collection of software tools (AutoCAD, EPLAN, SIMARIS SIVACON, SIMARIS DESIGN) which enable the complete automation of the development of graphical documentation of a power systems. In the fourth chapter, the application of software tools in the project management in power systems ...

  13. Comparison of cross culture engineering ethics training using the simulator for engineering ethics education. (United States)

    Chung, Christopher


    This paper describes the use and analysis of the Simulator for Engineering Ethics Education (SEEE) to perform cross culture engineering ethics training and analysis. Details describing the first generation and second generation development of the SEEE are published in Chung and Alfred, Science and Engineering Ethics, vol. 15, 2009 and Alfred and Chung, Science and Engineering Ethics, vol. 18, 2012. In this effort, a group of far eastern educated students operated the simulator in the instructional, training, scenario, and evaluation modes. The pre and post treatment performance of these students were compared to U.S. Educated students. Analysis of the performance indicated that the far eastern educated student increased their level of knowledge 23.7 percent while U.S. educated students increased their level of knowledge by 39.3 percent.

  14. Tissue engineering applications in periodontics: Alternate god

    Directory of Open Access Journals (Sweden)

    Samir Chugh


    Full Text Available "Tissue engineering" also referred as regenerative medicine indicates a new interdisciplinary initiative, which has the goal of growing tissues or organs directly from a single cell taken from an individual. Originally coined to denote the construction in the laboratory of a device containing viable cells and biologic mediators in a synthetic or biologic matrix that could be implanted in patients to facilitate regeneration. However, the term has crept into clinical armory of periodontists and has attained certain halo and glamour even when used in mundane and prosaic situations. Thus, this paper critically evaluates its role and application in clinical scenario.

  15. Ceramic applications in the advanced Stirling automotive engine (United States)

    Tomazic, W. A.; Cairelli, J. E.


    The ideal cycle, its application to a practical machine, and the specific advantages of high efficiency, low emissions, multi-fuel capability, and low noise of the stirling engine are discussed. Certain portions of the Stirling engine must operate continuously at high temperature. Ceramics offer the potential of cost reduction and efficiency improvement for advanced engine applications. Potential applications for ceramics in Stirling engines, and some of the special problems pertinent to using ceramics in the Stirling engine are described. The research and technology program in ceramics which is planned to support the development of advanced Stirling engines is outlined.

  16. Internal combustion engines performance simulation; Simulacao de desempenho de motores de combustao interna

    Energy Technology Data Exchange (ETDEWEB)

    Monteiro, Jose F.C.; Barbosa, Joao R. [Centro Tecnico Aeroespacial, Sao Jose dos Campos, SP (Brazil). Inst. Tecnologico de Aeronautica. Dept. de Energia]. E-mail:;


    A study of numerical methods for the simulation of internal combustion engines is presented. Functional blocks, representing each component of the engine, can be combined to simulate the engine. A model was selected for each component. The engine simulation is carried out connecting the functional blocks. The inviscid conservation equations coupled with loss models where solved using a C++ computer program. Engine performance simulation is shown and results compared with published data. (author)

  17. Building of Nuclear Ship Engineering Simulation System development of the simulator for the integral type reactor

    Energy Technology Data Exchange (ETDEWEB)

    Takahashi, Teruo; Shimazaki, Junya; Yabuuchi, Noriaki; Fukuhara, Yosifumi; Kusunoki, Takeshi; Ochiai, Masaaki [Department of Nuclear Energy Systems, Tokai Research Establishment, Japan Atomic Energy Research Institute, Tokai, Ibaraki (Japan); Nakazawa, Toshio [Department of HTTR Project, Oarai Research Establishment, Japan Atomic Energy Research Institute, Oarai, Ibaraki (Japan)


    JAERI had carried out the design study of a light-weight and compact integral type reactor of power 100 MW{sub th} with passive safety as a power source for the future nuclear ships, and completed an engineering design. To confirm the design and operation performance and to utilize the study of automation of the operations of reactor, we developed a real-time simulator for the integral type reactor. This simulator is a part of Nuclear Ship Engineering Simulation System (NESSY) and on the same hardware as 'Mutsu' simulator which was developed to simulate the first Japanese nuclear ship Mutsu'. Simulation accuracy of 'Mutsu' simulator was verified by comparing the simulation results With data got in the experimental voyage of 'Mutsu'. The simulator for the integral type reactor uses the same programs which were used in 'Mutsu' simulator for the separate type PWR, and the simulated results are approximately consistent with the calculated values using RELAP5/MOD2 (The later points are reported separately). Therefore simulation accuracy of the simulator for the integral type reactor is also expected to be reasonable, though it is necessary to verify by comparing with the real plant data or experimental data in future. We can get the perspectives to use as a real-time engineering simulator and to achieve the above-mentioned aims. This is a report on development of the simulator for the integral type reactor mainly focused on the contents of the analytical programs expressed the structural features of reactor. (author)

  18. Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Filipe, Joaquim; Kacprzyk, Janusz; Pina, Nuno


    This book includes extended and revised versions of a set of selected papers from the 2012 International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2012) which was sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC) and held in Rome, Italy. SIMULTECH 2012 was technically co-sponsored by the Society for Modeling & Simulation International (SCS), GDR I3, Lionphant Simulation, Simulation Team and IFIP and held in cooperation with AIS Special Interest Group of Modeling and Simulation (AIS SIGMAS) and the Movimento Italiano Modellazione e Simulazione (MIMOS).

  19. Tissue engineering skeletal muscle for orthopaedic applications (United States)

    Payumo, Francis C.; Kim, Hyun D.; Sherling, Michael A.; Smith, Lee P.; Powell, Courtney; Wang, Xiao; Keeping, Hugh S.; Valentini, Robert F.; Vandenburgh, Herman H.


    With current technology, tissue-engineered skeletal muscle analogues (bioartificial muscles) generate too little active force to be clinically useful in orthopaedic applications. They have been engineered genetically with numerous transgenes (growth hormone, insulinlike growth factor-1, erythropoietin, vascular endothelial growth factor), and have been shown to deliver these therapeutic proteins either locally or systemically for months in vivo. Bone morphogenetic proteins belonging to the transforming growth factor-beta superfamily are osteoinductive molecules that drive the differentiation pathway of mesenchymal cells toward the chondroblastic or osteoblastic lineage, and stimulate bone formation in vivo. To determine whether skeletal muscle cells endogenously expressing bone morphogenetic proteins might serve as a vehicle for systemic bone morphogenetic protein delivery in vivo, proliferating skeletal myoblasts (C2C12) were transduced with a replication defective retrovirus containing the gene for recombinant human bone morphogenetic protein-6 (C2BMP-6). The C2BMP-6 cells constitutively expressed recombinant human bone morphogenetic protein-6 and synthesized bioactive recombinant human bone morphogenetic protein-6, based on increased alkaline phosphatase activity in coincubated mesenchymal cells. C2BMP-6 cells did not secrete soluble, bioactive recombinant human bone morphogenetic protein-6, but retained the bioactivity in the cell layer. Therefore, genetically-engineered skeletal muscle cells might serve as a platform for long-term delivery of osteoinductive bone morphogenetic proteins locally.

  20. Simulation of Production Lines in the Education of Engineers: How to Choose the Right Software?

    Directory of Open Access Journals (Sweden)

    Rostkowska Marta


    Full Text Available The article discusses the problems of modeling and simulation in the design of production lines, mainly from an educator's perspective. Nowadays, there is a wide range of computer programs that can be used to design production lines and to simulate various aspects of their operation. However, the programs being available vary considerably as to their functionality, the approach to production system design, and the visualization tools. Therefore we demonstrate and evaluate in this paper four simulation programs, focusing on the easiness of system design, area of the possible applications in education of engineers, and the limitations imposed by versions dedicated for students. We evaluate three of programs for digital factory simulation on a common, simple assembly task, then demonstrate that these programs may be also used for more specialized simulations in various areas of production, and compare with a specialized program for simulation of robotised production lines and work cells.

  1. [Application status of rapid prototyping technology in artificial bone based on reverse engineering]. (United States)

    Fang, Ao; Zheng, Min; Fan, Ding


    Artificial bone replacement has made an important contribution to safeguard human health and improve the quality of life. The application requirements of rapid prototyping technology based on reverse engineering in individualized artificial bone with individual differences are particularly urgent. This paper reviewed the current research and applications of rapid prototyping and reverse engineering in artificial bone. The research developments and the outlook of bone kinematics and dynamics simulation are also introduced.

  2. Supercritical fluid mixing in Diesel Engine Applications (United States)

    Bravo, Luis; Ma, Peter; Kurman, Matthew; Tess, Michael; Ihme, Matthias; Kweon, Chol-Bum


    A numerical framework for simulating supercritical fluids mixing with large density ratios is presented in the context of diesel sprays. Accurate modeling of real fluid effects on the fuel air mixture formation process is critical in characterizing engine combustion. Recent work (Dahms, 2013) has suggested that liquid fuel enters the chamber in a transcritical state and rapidly evolves to supercritical regime where the interface transitions from a distinct liquid/gas interface into a continuous turbulent mixing layer. In this work, the Peng Robinson EoS is invoked as the real fluid model due to an acceptable compromise between accuracy and computational tractability. Measurements at supercritical conditions are reported from the Constant Pressure Flow (CPF) chamber facility at the Army Research Laboratory. Mie and Schlieren optical spray diagnostics are utilized to provide time resolved liquid and vapor penetration length measurement. The quantitative comparison presented is discussed. Oak Ridge Associated Universities (ORAU).

  3. Applications of metaheuristic optimization algorithms in civil engineering

    CERN Document Server

    Kaveh, A


    The book presents recently developed efficient metaheuristic optimization algorithms and their applications for solving various optimization problems in civil engineering. The concepts can also be used for optimizing problems in mechanical and electrical engineering.

  4. Application of systems engineering: An acquisition agent perspective

    CSIR Research Space (South Africa)

    Niken, A


    Full Text Available This article covers a descriptive case study on the application of systems engineering and systems engineering management at Armscor. The report also covers the investigation into development methods used and the how the requirements changes...

  5. Application of systems engineering: An acquisition agent perspective

    CSIR Research Space (South Africa)

    Niken, A


    Full Text Available This article covers a descriptive case study on the application of systems engineering and systems engineering management at Armscor. The report also covers the investigation into development methods used and the how the requirements changes...

  6. Intelligent techniques in engineering management theory and applications

    CERN Document Server

    Onar, Sezi


    This book presents recently developed intelligent techniques with applications and theory in the area of engineering management. The involved applications of intelligent techniques such as neural networks, fuzzy sets, Tabu search, genetic algorithms, etc. will be useful for engineering managers, postgraduate students, researchers, and lecturers. The book has been written considering the contents of a classical engineering management book but intelligent techniques are used for handling the engineering management problem areas. This comprehensive characteristics of the book makes it an excellent reference for the solution of complex problems of engineering management. The authors of the chapters are well-known researchers with their previous works in the area of engineering management.

  7. Launch Site Computer Simulation and its Application to Processes (United States)

    Sham, Michael D.


    This paper provides an overview of computer simulation, the Lockheed developed STS Processing Model, and the application of computer simulation to a wide range of processes. The STS Processing Model is an icon driven model that uses commercial off the shelf software and a Macintosh personal computer. While it usually takes one year to process and launch 8 space shuttles, with the STS Processing Model this process is computer simulated in about 5 minutes. Facilities, orbiters, or ground support equipment can be added or deleted and the impact on launch rate, facility utilization, or other factors measured as desired. This same computer simulation technology can be used to simulate manufacturing, engineering, commercial, or business processes. The technology does not require an 'army' of software engineers to develop and operate, but instead can be used by the layman with only a minimal amount of training. Instead of making changes to a process and realizing the results after the fact, with computer simulation, changes can be made and processes perfected before they are implemented.

  8. Introduction to tissue engineering and application for cartilage engineering. (United States)

    de Isla, N; Huseltein, C; Jessel, N; Pinzano, A; Decot, V; Magdalou, J; Bensoussan, D; Stoltz, J-F


    Tissue engineering is a multidisciplinary field that applies the principles of engineering, life sciences, cell and molecular biology toward the development of biological substitutes that restore, maintain, and improve tissue function. In Western Countries, tissues or cells management for clinical uses is a medical activity governed by different laws. Three general components are involved in tissue engineering: (1) reparative cells that can form a functional matrix; (2) an appropriate scaffold for transplantation and support; and (3) bioreactive molecules, such as cytokines and growth factors that will support and choreograph formation of the desired tissue. These three components may be used individually or in combination to regenerate organs or tissues. Thus the growing development of tissue engineering needs to solve four main problems: cells, engineering development, grafting and safety studies.

  9. Combustion Engines Development Mixture Formation, Combustion, Emissions and Simulation

    CERN Document Server

    Schwarz, Christian; Teichmann, Rüdiger


    In the development of engines and vehicles it is nowadays standard practice to use commercially available computing programmes for simulation, not only of the transient reaction of vehicles or of the complete driveshaft, but also of the highly unsteady processes in the combustion chamber of an engine. Normally the source code is not available for these computing programmes and it takes too much time to study the respective specifications, so the users often do not have sufficient knowledge about the physical and chemical contents of the approaches that the programmes are based on. We have often been faced with this fact in talks to employees or in discussions during the presentation of results of simulation. Therefore it is our aim to point out different physical and chemical approaches and to show the possibilities and limits of the models used.

  10. Numerical Simulation of Combustion Chamber for Button Turbojet Engine

    Directory of Open Access Journals (Sweden)

    Ma Hongpeng


    Full Text Available To provide reference data for ultra-micro combustor, a new type button turbojet engine was designed and simulated the combustion’s steady-state process. The boundary condition of inlet was calculated using isentropic numerical calculation, taken into turbulent chemical reaction, heat radiation, and so on, getting the combustion chamber’s steady-state of the velocity, temperature and component concentration distribution, analysis the fuel/air flow and backflow, combustion efficiency and total pressure recovery coefficient, and compared with the experimental data. The calculation results can accurately reflect the actual combustion. The results show that combustion chamber exit velocity is about 65m/s, outlet temperature is around 1000K, the simulation and experimental data are similar, combustion chamber structure design is reasonable, and this paper will provide a basis for the future improvement of the millimeter scale turbojet engine.

  11. Optical engine initiation: multiple compartment applications (United States)

    Hunt, Jeffrey H.


    Modern day propulsion systems are used in aerospace applications for different purposes. The aerospace industry typically requires propulsion systems to operate in a rocket mode in order to drive large boost vehicles. The defense industry generally requires propulsion systems to operate in an air-breathing mode in order to drive missiles. A mixed system could use an air-breathing first stage and a rocket-mode upper stage for space access. Thus, propulsion systems can be used for high mass payloads and where the payload is dominated by the fuel/oxidizer mass being used by the propulsion system. The pulse detonation wave engine (PDWE) uses an alternative type of detonation cycle to achieve the same propulsion results. The primary component of the PDWE is the combustion chamber (or detonation tube). The PDWE represents an attractive propulsion source since its engine cycle is thermodynamically closest to that of a constant volume reaction. This characteristic leads to the inference that a maximum of the potential energy of the PDWE is put into thrust and not into flow work. Consequently, the volume must be increased. The technical community has increasingly adopted the alternative choice of increasing total volume by designing the engine to include a set of banks of smaller combustion chambers. This technique increases the complexity of the ignition subsystem because the inter-chamber timing must be considered. Current approaches to igniting the PDWE have involved separate shock or blast wave initiators and chemical additives designed to enhance detonatibility. An optical ignition subsystem generates a series of optical pulses, where the optical pulses ignite the fuel/oxidizer mixture such that the chambers detonate in a desired order. The detonation system also has an optical transport subsystem for transporting the optical pulses from the optical ignition subsystem to the chambers. The use of optical ignition and transport provides a non-toxic, small, lightweight

  12. The future of simulations for space applications (United States)

    Matsumoto, H.

    Space development has been rapidly increasing and there will be huge investment by business markets for space development and applications such as space factory and Solar Power Station (SPS). In such a situation, we would like to send a warning message regarding the future space simulations. It is widely recognized that space simulation have been contributing to the quantitative understanding of various plasma phenomena occurring in the solarterrestrial environment. In the current century, however, in addition to the conventional contribution to the solar-terrestrial physics, we also have to pay our attention to the application of space simulation for human activities in space. We believe that space simulations can be a a powerful and helpful tool for the understanding the spacecraft-environment interactions occurring in space development and applications. The global influence by exhausted heavy ions from electric propulsion on the plasmasphere can be also analyzed by the combination of MHD and particle simulations. The results obtained in the simulations can provide us very significant and beneficial information so that we can minimize the undesirable effects in space development and applications. 1 Brief history of ISSS and contribution to the space plasma physics Numerical simulation has been largely recognized as a powerful tool in the advance of space plasma physics. The International School for Space Simulation (ISSS) series was set up in order to emphasize such a recognition in the early eighties, on the common initiative of M. Ashour-Abdalla, R. Gendrin, T. Sato and myself. The preceding five ISSS's (in Japan, USA, France, Japan, and Japan again) have greatly contributed to the promotion of and advance of computer simulations as well as the education of students trying to start the simulation study for their own research objectives.

  13. Simulational nanoengineering: Molecular dynamics implementation of an atomistic Stirling engine. (United States)

    Rapaport, D C


    A nanoscale-sized Stirling engine with an atomistic working fluid has been modeled using molecular dynamics simulation. The design includes heat exchangers based on thermostats, pistons attached to a flywheel under load, and a regenerator. Key aspects of the behavior, including the time-dependent flows, are described. The model is shown to be capable of stable operation while producing net work at a moderate level of efficiency.

  14. Blood Pump Development Using Rocket Engine Flow Simulation Technology (United States)

    Kiris, Cetin C.; Kwak, Dochan


    This viewgraph presentation provides information on the transfer of rocket engine flow simulation technology to work involving the development of blood pumps. Details are offered regarding the design and requirements of mechanical heart assist devices, or VADs (ventricular assist device). There are various computational fluid dynamics issues involved in the visualization of flow in such devices, and these are highlighted and compared to those of rocket turbopumps.

  15. Evaluation of heat engine for hybrid vehicle application (United States)

    Schneider, H. W.


    The status of ongoing heat-engine developments, including spark-ignition, compression-ignition, internal-combustion, and external-combustion engines is presented. The potential of engine concepts under consideration for hybrid vehicle use is evaluated, using self-imposed criteria for selection. The deficiencies of the engines currently being evaluated in hybrid vehicles are discussed. Focus is on recent research with two-stroke, rotary, and free-piston engines. It is concluded that these engine concepts have the most promising potential for future application in hybrid vehicles. Recommendations are made for analysis and experimentation to evaluate stop-start and transient emission behavior of recommended engine concepts.

  16. A Virtual Engineering Framework for Simulating Advanced Power System

    Energy Technology Data Exchange (ETDEWEB)

    Mike Bockelie; Dave Swensen; Martin Denison; Stanislav Borodai


    In this report is described the work effort performed to provide NETL with VE-Suite based Virtual Engineering software and enhanced equipment models to support NETL's Advanced Process Engineering Co-simulation (APECS) framework for advanced power generation systems. Enhancements to the software framework facilitated an important link between APECS and the virtual engineering capabilities provided by VE-Suite (e.g., equipment and process visualization, information assimilation). Model enhancements focused on improving predictions for the performance of entrained flow coal gasifiers and important auxiliary equipment (e.g., Air Separation Units) used in coal gasification systems. In addition, a Reduced Order Model generation tool and software to provide a coupling between APECS/AspenPlus and the GE GateCycle simulation system were developed. CAPE-Open model interfaces were employed where needed. The improved simulation capability is demonstrated on selected test problems. As part of the project an Advisory Panel was formed to provide guidance on the issues on which to focus the work effort. The Advisory Panel included experts from industry and academics in gasification, CO2 capture issues, process simulation and representatives from technology developers and the electric utility industry. To optimize the benefit to NETL, REI coordinated its efforts with NETL and NETL funded projects at Iowa State University, Carnegie Mellon University and ANSYS/Fluent, Inc. The improved simulation capabilities incorporated into APECS will enable researchers and engineers to better understand the interactions of different equipment components, identify weaknesses and processes needing improvement and thereby allow more efficient, less expensive plants to be developed and brought on-line faster and in a more cost-effective manner. These enhancements to APECS represent an important step toward having a fully integrated environment for performing plant simulation and engineering

  17. Discrete Event Modeling and Simulation-Driven Engineering for the ATLAS Data Acquisition Network

    CERN Document Server

    Bonaventura, Matias Alejandro; The ATLAS collaboration; Castro, Rodrigo Daniel


    We present an iterative and incremental development methodology for simulation models in network engineering projects. Driven by the DEVS (Discrete Event Systems Specification) formal framework for modeling and simulation we assist network design, test, analysis and optimization processes. A practical application of the methodology is presented for a case study in the ATLAS particle physics detector, the largest scientific experiment built by man where scientists around the globe search for answers about the origins of the universe. The ATLAS data network convey real-time information produced by physics detectors as beams of particles collide. The produced sub-atomic evidences must be filtered and recorded for further offline scrutiny. Due to the criticality of the transported data, networks and applications undergo careful engineering processes with stringent quality of service requirements. A tight project schedule imposes time pressure on design decisions, while rapid technology evolution widens the palett...

  18. Application of Internet in Road Traffic Engineering

    Directory of Open Access Journals (Sweden)

    Ivan Dadić


    Full Text Available The paper deals with the implementation of Internet in trafficengineering with the purpose of improving the professionaland scientific research development of the traffic system in theRepublic of Croatia.Fast growth of the world computer network, Internet, andits applications in almost all the fields of human activities,change the picture of the modern world. The current exchangeof data in all their forms and the daily growth of the network,supplemented by almost incredible amounts of data that can bealmost instantly accessible, indicates that Internet is not just theinfomwtion technology revolution, but that it is a revolutionper se. More than 100 million computers are estimated to benetworked beginning of the 21" century.Internet seems almost as if it were created for the purposesof knowledge and expe1ience exchange in traffic, a relativelyyoung scientific branch. 11 can be concluded that the presenceof traffic engineers in Internet is today's reality and tomon·ow'snecessity.

  19. Civil engineering applications of ground penetrating radar

    CERN Document Server

    Pajewski, Lara


    This book, based on Transport and Urban Development COST Action TU1208, presents the most advanced applications of ground penetrating radar (GPR) in a civil engineering context, with documentation of instrumentation, methods, and results. It explains clearly how GPR can be employed for the surveying of critical transport infrastructure, such as roads, pavements, bridges, and tunnels, and for the sensing and mapping of underground utilities and voids. Detailed attention is also devoted to use of GPR in the inspection of geological structures and of construction materials and structures, including reinforced concrete, steel reinforcing bars, and pre/post-tensioned stressing ducts. Advanced methods for solution of electromagnetic scattering problems and new data processing techniques are also presented. Readers will come to appreciate that GPR is a safe, advanced, nondestructive, and noninvasive imaging technique that can be effectively used for the inspection of composite structures and the performance of diagn...

  20. Soft computing techniques in engineering applications

    CERN Document Server

    Zhong, Baojiang


    The Soft Computing techniques, which are based on the information processing of biological systems are now massively used in the area of pattern recognition, making prediction & planning, as well as acting on the environment. Ideally speaking, soft computing is not a subject of homogeneous concepts and techniques; rather, it is an amalgamation of distinct methods that confirms to its guiding principle. At present, the main aim of soft computing is to exploit the tolerance for imprecision and uncertainty to achieve tractability, robustness and low solutions cost. The principal constituents of soft computing techniques are probabilistic reasoning, fuzzy logic, neuro-computing, genetic algorithms, belief networks, chaotic systems, as well as learning theory. This book covers contributions from various authors to demonstrate the use of soft computing techniques in various applications of engineering.  

  1. Mobile Prototyping Platforms for Remote Engineering Applications

    Directory of Open Access Journals (Sweden)

    Karsten Henke


    Full Text Available This paper describes a low-cost mobile communication platform as a universal rapid-prototyping system, which is based on the Quadrocopter concept. At the Integrated Hardware and Software Systems Group at the Ilmenau University of Technology these mobile platforms are used to motivate bachelor and master students to study Computer Engineering sciences. This could be done by increasing their interest in technical issues, using this platform as integral part of a new ad-hoc lab to demonstrate different aspects in the area of Mobile Communication as well as universal rapid prototyping nodes to investigate different mechanisms for self-organized mobile communication systems within the International Graduate School on Mobile Communications. Beside the three fields of application, the paper describes the current architecture concept of the mobile prototyping platform as well as the chosen control mechanism and the assigned sensor systems to fulfill all the required tasks.

  2. Software engineering processes principles and applications

    CERN Document Server

    Wang, Yingxu


    Fundamentals of the Software Engineering ProcessIntroductionA Unified Framework of the Software Engineering ProcessProcess AlgebraProcess-Based Software EngineeringSoftware Engineering Process System ModelingThe CMM ModelThe ISO 9001 ModelThe BOOTSTRAP ModelThe ISO/IEC 15504 (SPICE) ModelThe Software Engineering Process Reference Model: SEPRMSoftware Engineering Process System AnalysisBenchmarking the SEPRM ProcessesComparative Analysis of Current Process ModelsTransformation of Capability Levels Between Current Process ModelsSoftware Engineering Process EstablishmentSoftware Process Establish

  3. Application of Chaos Theory to Engine Systems


    Matsumoto, Kazuhiro; Diebner, Hans H.; Tsuda, Ichiro; Hosoi, Yukiharu


    We focus on the control issue for engine systems from the perspective of chaos theory, which is based on the fact that engine systems have a low-dimensional chaotic dynamics. Two approaches are discussed: controlling chaos and harnessing chaos, respectively. We apply Pyragas' chaos control method to an actual engine system. The experimental results show that the chaotic motion of an engine system may be stabilized to a periodic motion. Alternatively, harnessing chaos for engine systems is add...

  4. Lean NOx Trap Catalysis for Lean Natural Gas Engine Applications

    Energy Technology Data Exchange (ETDEWEB)

    Parks, II, James E [ORNL; Storey, John Morse [ORNL; Theiss, Timothy J [ORNL; Ponnusamy, Senthil [ORNL; Ferguson, Harley Douglas [ORNL; Williams, Aaron M [ORNL; Tassitano, James B [ORNL


    efficiency and emissions of natural gas reciprocating engines are being pursued. Approaches include: stoichiometric engine operation with exhaust gas recirculation and three-way catalysis, advanced combustion modes such as homogeneous charge compression ignition, and extension of the lean combustion limit with advanced ignition concepts and/or hydrogen mixing. The research presented here addresses the technical approach of combining efficient lean spark-ignited natural gas combustion with low emissions obtained from a lean NOx trap catalyst aftertreatment system. This approach can be applied to current lean engine technology or advanced lean engines that may result from related efforts in lean limit extension. Furthermore, the lean NOx trap technology has synergy with hydrogen-assisted lean limit extension since hydrogen is produced from natural gas during the lean NOx trap catalyst system process. The approach is also applicable to other lean engines such as diesel engines, natural gas turbines, and lean gasoline engines; other research activities have focused on those applications. Some commercialization of the technology has occurred for automotive applications (both diesel and lean gasoline engine vehicles) and natural gas turbines for stationary power. The research here specifically addresses barriers to commercialization of the technology for large lean natural gas reciprocating engines for stationary power. The report presented here is a comprehensive collection of research conducted by Oak Ridge National Laboratory (ORNL) on lean NOx trap catalysis for lean natural gas reciprocating engines. The research was performed in the Department of Energy's ARES program from 2003 to 2007 and covers several aspects of the technology. All studies were conducted at ORNL on a Cummins C8.3G+ natural gas engine chosen based on industry input to simulate large lean natural gas engines. Specific technical areas addressed by the research include: NOx reduction efficiency, partial

  5. Research of Simulation in Character Animation Based on Physics Engine

    Directory of Open Access Journals (Sweden)

    Yang Yu


    Full Text Available Computer 3D character animation essentially is a product, which is combined with computer graphics and robotics, physics, mathematics, and the arts. It is based on computer hardware and graphics algorithms and related sciences rapidly developed new technologies. At present, the mainstream character animation technology is based on the artificial production of key technologies and capture frames based on the motion capture device technology. 3D character animation is widely used not only in the production of film, animation, and other commercial areas but also in virtual reality, computer-aided education, flight simulation, engineering simulation, military simulation, and other fields. In this paper, we try to study physics based character animation to solve these problems such as poor real-time interaction that appears in the character, low utilization rate, and complex production. The paper deeply studied the kinematics, dynamics technology, and production technology based on the motion data. At the same time, it analyzed ODE, PhysX, Bullet, and other variety of mainstream physics engines and studied OBB hierarchy bounding box tree, AABB hierarchical tree, and other collision detection algorithms. Finally, character animation based on ODE is implemented, which is simulation of the motion and collision process of a tricycle.

  6. A Survey of High-Quality Computational Libraries and their Impactin Science and Engineering Applications

    Energy Technology Data Exchange (ETDEWEB)

    Drummond, L.A.; Hernandez, V.; Marques, O.; Roman, J.E.; Vidal, V.


    Recently, a number of important scientific and engineering problems have been successfully studied and solved by means of computational modeling and simulation. Many of these computational models and simulations benefited from the use of available software tools and libraries to achieve high performance and portability. In this article, we present a reference matrix of the performance of robust, reliable and widely used tools mapped to scientific and engineering applications that use them. We aim at regularly maintaining and disseminating this matrix to the computational science community. This matrix will contain information on state-of-the-art computational tools, their applications and their use.

  7. Research Needs and Impacts in Predictive Simulation for Internal Combustion Engines (PreSICE)

    Energy Technology Data Exchange (ETDEWEB)

    Eckerle, Wayne [Cummins, Inc., Columbus, IN (United States); Rutland, Chris [Univ. of Wisconsin, Madison, WI (United States); Rohlfing, Eric [Dept. of Energy (DOE), Washington DC (United States). Office of Science; Singh, Gurpreet [Dept. of Energy (DOE), Washington DC (United States). Office of Energy Efficiency and Renewable Energy; McIlroy, Andrew [Sandia National Lab. (SNL-CA), Livermore, CA (United States)


    outcome will be: New and deeper understanding of the relevant fundamental physical and chemical processes in advanced combustion technologies, Implementation of this understanding into models and simulation tools appropriate for both exploration and design, and Sufficient validation with uncertainty quantification to provide confidence in the simulation results. These outcomes will provide the design tools for industry to reduce development time by up to 30% and improve engine efficiencies by 30% to 50%. The improved efficiencies applied to the national mix of transportation applications have the potential to save over 5 million barrels of oil per day, a current cost savings of $500 million per day.

  8. Engineering-Based Thermal CFD Simulations on Massive Parallel Systems

    Directory of Open Access Journals (Sweden)

    Jérôme Frisch


    Full Text Available The development of parallel Computational Fluid Dynamics (CFD codes is a challenging task that entails efficient parallelization concepts and strategies in order to achieve good scalability values when running those codes on modern supercomputers with several thousands to millions of cores. In this paper, we present a hierarchical data structure for massive parallel computations that supports the coupling of a Navier–Stokes-based fluid flow code with the Boussinesq approximation in order to address complex thermal scenarios for energy-related assessments. The newly designed data structure is specifically designed with the idea of interactive data exploration and visualization during runtime of the simulation code; a major shortcoming of traditional high-performance computing (HPC simulation codes. We further show and discuss speed-up values obtained on one of Germany’s top-ranked supercomputers with up to 140,000 processes and present simulation results for different engineering-based thermal problems.

  9. FPGA Simulation Engine for Customized Construction of Neural Microcircuits (United States)

    Blair, Hugh T.; Cong, Jason; Wu, Di


    In this paper we describe an FPGA-based platform for high-performance and low-power simulation of neural microcircuits composed from integrate-and-fire (IAF) neurons. Based on high-level synthesis, our platform uses design templates to map hierarchies of neuron model to logic fabrics. This approach bypasses high design complexity and enables easy optimization and design space exploration. We demonstrate the benefits of our platform by simulating a variety of neural microcircuits that perform oscillatory path integration, which evidence suggests may be a critical building block of the navigation system inside a rodent’s brain. Experiments show that our FPGA simulation engine for oscillatory neural microcircuits can achieve up to 39× speedup compared to software benchmarks on commodity CPU, and 232× energy reduction compared to embedded ARM core. PMID:25584120

  10. Engineering-Based Thermal CFD Simulations on Massive Parallel Systems

    KAUST Repository

    Frisch, Jérôme


    The development of parallel Computational Fluid Dynamics (CFD) codes is a challenging task that entails efficient parallelization concepts and strategies in order to achieve good scalability values when running those codes on modern supercomputers with several thousands to millions of cores. In this paper, we present a hierarchical data structure for massive parallel computations that supports the coupling of a Navier–Stokes-based fluid flow code with the Boussinesq approximation in order to address complex thermal scenarios for energy-related assessments. The newly designed data structure is specifically designed with the idea of interactive data exploration and visualization during runtime of the simulation code; a major shortcoming of traditional high-performance computing (HPC) simulation codes. We further show and discuss speed-up values obtained on one of Germany’s top-ranked supercomputers with up to 140,000 processes and present simulation results for different engineering-based thermal problems.

  11. Optoisolation circuits nonlinearity applications in engineering : optoisolation nonlinear dynamics and chaos, application in engineering

    CERN Document Server

    Aluf, Ofer


    This book describes a new concept in analyzing circuits, which includes optoisolation elements. The analysis is based on nonlinear dynamics and chaos models and shows comprehensive benefits and results. All conceptual optoisolation circuits are innovative and can be broadly implemented in engineering applications. The dynamics of optoisolation circuits provides several ways to use them in a variety of applications covering wide areas. The presentation fills the gap of analytical methods for optoisolation circuits analysis, concrete examples, and geometric examples. The optoisolation circuits analysis is developed systematically, starting with basic optoisolation circuits differential equations and their bifurcations, followed by Fixed points analysis, limit cycles and their bifurcations. Optoisolation circuits can be characterized as Lorenz equations, chaos, iterated maps, period doubling and attractors. This book is aimed at electrical and electronic engineers, students and researchers in physics as well. A ...

  12. CMC Technology Advancements for Gas Turbine Engine Applications (United States)

    Grady, Joseph E.


    CMC research at NASA Glenn is focused on aircraft propulsion applications. The objective is to enable reduced engine emissions and fuel consumption for more environmentally friendly aircraft. Engine system studies show that incorporation of ceramic composites into turbine engines will enable significant reductions in emissions and fuel burn due to increased engine efficiency resulting from reduced cooling requirements for hot section components. This presentation will describe recent progress and challenges in developing fiber and matrix constituents for 2700 F CMC turbine applications. In addition, ongoing research in the development of durable environmental barrier coatings, ceramic joining integration technologies and life prediction methods for CMC engine components will be reviewed.

  13. Microbial xylanases: engineering, production and industrial applications. (United States)

    Juturu, Veeresh; Wu, Jin Chuan


    and paper industries for a longer time but more and more attention has been paid to using them in producing sugars and other chemicals from lignocelluloses in recent years. Mining new genes from nature, rational engineering of known genes and directed evolution of these genes are required to get tailor-made xylanases for various industrial applications. Copyright © 2011 Elsevier Inc. All rights reserved.

  14. Extracellular matrix and tissue engineering applications

    NARCIS (Netherlands)

    Fernandes, H.A.M.; Moroni, Lorenzo; van Blitterswijk, Clemens; de Boer, Jan


    The extracellular matrix is a key component during regeneration and maintenance of tissues and organs, and it therefore plays a critical role in successful tissue engineering as well. Tissue engineers should recognise that engineering technology can be deduced from natural repair processes. Due to

  15. Engineering Mechanics and Design Applications Transdisciplinary Engineering Fundamentals

    CERN Document Server

    Ertas, Atila


    In the last decade, the number of complex problems facing engineers has increased, and the technical knowledge required to address and mitigate them continues to evolve rapidly. These problems include not only the design of engineering systems with numerous components and subsystems, but also the design, redesign, and interaction of social, political, managerial, commercial, biological, medical, and other systems. These systems are likely to be dynamic and adaptive in nature. Finding creative solutions to such large-scale, unstructured problems requires activities that cut across traditional d

  16. Integrated Turbine Tip Clearance and Gas Turbine Engine Simulation (United States)

    Chapman, Jeffryes W.; Kratz, Jonathan; Guo, Ten-Huei; Litt, Jonathan


    Gas turbine compressor and turbine blade tip clearance (i.e., the radial distance between the blade tip of an axial compressor or turbine and the containment structure) is a major contributing factor to gas path sealing, and can significantly affect engine efficiency and operational temperature. This paper details the creation of a generic but realistic high pressure turbine tip clearance model that may be used to facilitate active tip clearance control system research. This model uses a first principles approach to approximate thermal and mechanical deformations of the turbine system, taking into account the rotor, shroud, and blade tip components. Validation of the tip clearance model shows that the results are realistic and reflect values found in literature. In addition, this model has been integrated with a gas turbine engine simulation, creating a platform to explore engine performance as tip clearance is adjusted. Results from the integrated model explore the effects of tip clearance on engine operation and highlight advantages of tip clearance management.

  17. Interactive simulations as teaching tools for engineering mechanics courses (United States)

    Carbonell, Victoria; Romero, Carlos; Martínez, Elvira; Flórez, Mercedes


    This study aimed to gauge the effect of interactive simulations in class as an active teaching strategy for a mechanics course. Engineering analysis and design often use the properties of planar sections in calculations. In the stress analysis of a beam under bending and torsional loads, cross-sectional properties are used to determine stress and displacement distributions in the beam cross section. The centroid, moments and products of inertia of an area made up of several common shapes (rectangles usually) may thus be obtained by adding the moments of inertia of the component areas (U-shape, L-shape, C-shape, etc). This procedure is used to calculate the second moments of structural shapes in engineering practice because the determination of their moments of inertia is necessary for the design of structural components. This paper presents examples of interactive simulations developed for teaching the ‘Mechanics and mechanisms’ course at the Universidad Politecnica de Madrid, Spain. The simulations focus on fundamental topics such as centroids, the properties of the moment of inertia, second moments of inertia with respect to two axes, principal moments of inertia and Mohr's Circle for plane stress, and were composed using Geogebra software. These learning tools feature animations, graphics and interactivity and were designed to encourage student participation and engagement in active learning activities, to effectively explain and illustrate course topics, and to build student problem-solving skills.

  18. Hyperthermal Environments Simulator for Nuclear Rocket Engine Development (United States)

    Litchford, Ron J.; Foote, John P.; Clifton, W. B.; Hickman, Robert R.; Wang, Ten-See; Dobson, Christopher C.


    An arc-heater driven hyperthermal convective environments simulator was recently developed and commissioned for long duration hot hydrogen exposure of nuclear thermal rocket materials. This newly established non-nuclear testing capability uses a high-power, multi-gas, wall-stabilized constricted arc-heater to produce hightemperature pressurized hydrogen flows representative of nuclear reactor core environments, excepting radiation effects, and is intended to serve as a low-cost facility for supporting non-nuclear developmental testing of hightemperature fissile fuels and structural materials. The resulting reactor environments simulator represents a valuable addition to the available inventory of non-nuclear test facilities and is uniquely capable of investigating and characterizing candidate fuel/structural materials, improving associated processing/fabrication techniques, and simulating reactor thermal hydraulics. This paper summarizes facility design and engineering development efforts and reports baseline operational characteristics as determined from a series of performance mapping and long duration capability demonstration tests. Potential follow-on developmental strategies are also suggested in view of the technical and policy challenges ahead. Keywords: Nuclear Rocket Engine, Reactor Environments, Non-Nuclear Testing, Fissile Fuel Development.

  19. 2003 SNL ASCI applications software quality engineering assessment report.

    Energy Technology Data Exchange (ETDEWEB)

    Schofield, Joseph Richard, Jr.; Ellis, Molly A.; Williamson, Charles Michael; Bonano, Lora A.


    This document describes the 2003 SNL ASCI Software Quality Engineering (SQE) assessment of twenty ASCI application code teams and the results of that assessment. The purpose of this assessment was to determine code team compliance with the Sandia National Laboratories ASCI Applications Software Quality Engineering Practices, Version 2.0 as part of an overall program assessment.

  20. A Phenomenological Heat Transfer Model of SI EnginesApplication to the Simulation of a Full-Hybrid Vehicle Un modèle phénoménologique de transfert thermique au sein de moteurs à allumage commandé — Application à la simulation d’un véhicule full-hybride

    Directory of Open Access Journals (Sweden)

    Dubouil R.


    Full Text Available A hybrid thermal-electric vehicle allows some significant fuel economy due to its peculiar use of the Internal Combustion Engine (ICE that runs with better efficiency. However, this propulsion system impacts its thermal behaviour, especially during its warm-up after a cold start. The ICE can indeed be shut down when the vehicle is stopped (Stop&Start system and during full-electric propulsion mode (allowed at light speed and load if the battery state of charge is high enough resulting in a lack of heat source and a slow down of the warm-up. Moreover, the use of the ICE at higher loads while charging the batteries provides an increase of the heating power generated by the combustion. Control strategies in a hybrid vehicle (energy repartition between the two propulsions: thermal and electric have a significant effect on its final consumption. Therefore, the simulation of hybrid vehicles is then useful to evaluate the efficiency of these strategies. However, the consideration of the warm-up of the ICE in such a propulsion system was done in only few published studies. A simulation tool using the Amesim software has been developed in order to simulate the warm-up of an ICE used in a hybrid parallel propulsion system. The corresponding model is developed in order to take into account the thermal phenomena occurring between the different ICE components. Thus, a thermodynamic model is coupled with a thermal model of the metallic parts and the different fluid loops (water and oil. Their mean temperature dependence with different parameters like speed, the load, the cylinder geometry and the spark advance, is studied with the aim at reducing fuel consumption. The thermal model of the engine is finally integrated in a simulation of the whole vehicle. The thermal behaviour of a parallel electric full-hybrid vehicle using a spark ignition engine is then presented using this simulation tool. The simulation results show the impact of the peculiar use of the

  1. System Engineering Strategy for Distributed Multi-Purpose Simulation Architectures (United States)

    Bhula, Dlilpkumar; Kurt, Cindy Marie; Luty, Roger


    This paper describes the system engineering approach used to develop distributed multi-purpose simulations. The multi-purpose simulation architecture focuses on user needs, operations, flexibility, cost and maintenance. This approach was used to develop an International Space Station (ISS) simulator, which is called the International Space Station Integrated Simulation (ISIS)1. The ISIS runs unmodified ISS flight software, system models, and the astronaut command and control interface in an open system design that allows for rapid integration of multiple ISS models. The initial intent of ISIS was to provide a distributed system that allows access to ISS flight software and models for the creation, test, and validation of crew and ground controller procedures. This capability reduces the cost and scheduling issues associated with utilizing standalone simulators in fixed locations, and facilitates discovering unknowns and errors earlier in the development lifecycle. Since its inception, the flexible architecture of the ISIS has allowed its purpose to evolve to include ground operator system and display training, flight software modification testing, and as a realistic test bed for Exploration automation technology research and development.

  2. Simulation of air pollution due to marine engines (United States)

    Stan, L. C.


    This paperwork tried to simulate the combustion inside the marine engines using the newest computer methods and technologies with the result of a diverse and rich palette of solutions, extremely useful for the study and prediction of complex phenomena of the fuel combustion. The paperwork is contributing to the theoretical systematization of the area of interest bringing into attention a thoroughly inventory of the thermodynamic description of the phenomena which take place in the combustion process into the marine diesel engines; to the in depth multidimensional combustion models description along with the interdisciplinary phenomenology taking place in the combustion models; to the FEA (Finite Elements Method) modelling for the combustion chemistry in the nonpremixed mixtures approach considered too; the CFD (Computational Fluid Dynamics) model was issued for the combustion area and a rich palette of results interesting for any researcher of the process.

  3. Efficient quantum optical state engineering and applications (United States)

    McCusker, Kevin T.

    Over a century after the modern prediction of the existence of individual particles of light by Albert Einstein, a reliable source of this simple quantum state of one photon does not exist. While common light sources such as a light bulb, LED, or laser can produce a pulse of light with an average of one photon, there is (currently) no way of knowing the number of photons in that pulse without first absorbing (and thereby destroying) them. Spontaneous parametric down-conversion, a process in which one high-energy photon splits into two lower-energy photons, allows us to prepare a single-photon state by detecting one of the photons, which then heralds the existence of its twin. This process has been the workhorse of quantum optics, allowing demonstrations of a myriad of quantum processes and protocols, such as entanglement, cryptography, superdense coding, teleportation, and simple quantum computing demonstrations. All of these processes would benefit from better engineering of the underlying down-conversion process, but despite significant effort (both theoretical and experimental), optimization of this process is ongoing. The focus of this work is to optimize certain aspects of a down-conversion source, and then use this tool in novel experiments not otherwise feasible. Specifically, the goal is to optimize the heralding efficiency of the down-conversion photons, i.e., the probability that if one photon is detected, the other photon is also detected. This source is then applied to two experiments (a single-photon source, and a quantum cryptography implementation), and the detailed theory of an additional application (a source of Fock states and path-entangled states, called N00N states) is discussed, along with some other possible applications.

  4. Environmental implications and applications of engineered ... (United States)

    This review focus on environmental implications and applications of engineered magnetite (Fe3O4) nanoparticles (MNPs) as a single phase or a component of a hybrid nanocomposite that take advantages of their superparamagnetism and high surface area. MNPs are synthesized via co-precipitation, thermal decomposition, hydrothermal process, emulsion, and microbial process. Aggregation/sedimentation and transport of MNPs depend on surface charge of MNPs and geochemical parameters such as pH, ionic strength, and organic matter. MNPs generally have low toxicity to humans and ecosystem. MNPs are used for making excellent anode electrode materials in lithium-ion battery, for constructing biosensors, and for catalyzing a variety of chemical reactions. MNPs are used for air cleanup and carbon sequestration. MNP nanocomposites are made as antimicrobial agent for water disinfection and flocculants for water treatment. Conjugated MNPs are widely used for adsorptive/separative removal of organics, dye, oil, arsenic, Cr(VI), heavy metals, radionuclides, and rare earth elements. MNPs can degrade organic/inorganic contaminants via chemical reduction or oxidation in water, sediment, and soil. Future studies should further explore mechanisms of MNP interactions with other nanomaterials and contaminants, economic and green approaches of MNP synthesis, and field scale demonstration of MNP utilization. Submit to Journal of Hazardous Materials.

  5. Simulation of liquid propellant rocket engine combustion instabilities (United States)

    Ventrice, M. B.; Fang, J. C.; Purdy, K. R.


    A simulation technique for studying the high frequency combustion instabilities of liquid propellant rocket engines has been developed and used to investigate various aspects of instability phenomena. Of importance was investigation of the significance of the method of coupling the combustion and the gas dynamics of the system. Two coupling processes were studied: linear response of the combustion process to pressure fluctuations, and the nature of the resulting instabilities; and nonlinear response of the combustion process to velocity fluctuations, and the nature of the resulting instabilities. For the combustion model studied, nonlinear (velocity) coupling was found to more closely characterize liquid propellant instabilities.

  6. Preparation of laponite bioceramics for potential bone tissue engineering applications.

    Directory of Open Access Journals (Sweden)

    Chuanshun Wang

    Full Text Available We report a facile approach to preparing laponite (LAP bioceramics via sintering LAP powder compacts for bone tissue engineering applications. The sintering behavior and mechanical properties of LAP compacts under different temperatures, heating rates, and soaking times were investigated. We show that LAP bioceramic with a smooth and porous surface can be formed at 800°C with a heating rate of 5°C/h for 6 h under air. The formed LAP bioceramic was systematically characterized via different methods. Our results reveal that the LAP bioceramic possesses an excellent surface hydrophilicity and serum absorption capacity, and good cytocompatibility and hemocompatibility as demonstrated by resazurin reduction assay of rat mesenchymal stem cells (rMSCs and hemolytic assay of pig red blood cells, respectively. The potential bone tissue engineering applicability of LAP bioceramic was explored by studying the surface mineralization behavior via soaking in simulated body fluid (SBF, as well as the surface cellular response of rMSCs. Our results suggest that LAP bioceramic is able to induce hydroxyapatite deposition on its surface when soaked in SBF and rMSCs can proliferate well on the LAP bioceramic surface. Most strikingly, alkaline phosphatase activity together with alizarin red staining results reveal that the produced LAP bioceramic is able to induce osteoblast differentiation of rMSCs in growth medium without any inducing factors. Finally, in vivo animal implantation, acute systemic toxicity test and hematoxylin and eosin (H&E-staining data demonstrate that the prepared LAP bioceramic displays an excellent biosafety and is able to heal the bone defect. Findings from this study suggest that the developed LAP bioceramic holds a great promise for treating bone defects in bone tissue engineering.

  7. Applications of sliding mode control in science and engineering

    CERN Document Server

    Lien, Chang-Hua


    Gathering 20 chapters contributed by respected experts, this book reports on the latest advances in and applications of sliding mode control in science and engineering. The respective chapters address applications of sliding mode control in the broad areas of chaos theory, robotics, electrical engineering, physics, chemical engineering, memristors, mechanical engineering, environmental engineering, finance, and biology. Special emphasis has been given to papers that offer practical solutions, and which examine design and modeling involving new types of sliding mode control such as higher order sliding mode control, terminal sliding mode control, super-twisting sliding mode control, and integral sliding mode control. This book serves as a unique reference guide to sliding mode control and its recent applications for graduate students and researchers with a basic knowledge of electrical and control systems engineering.

  8. International conference on Information Engineering and Applications (IEA) 2012

    CERN Document Server


    Information engineering and applications is the field of study concerned with constructing information computing, intelligent systems, mathematical models, numerical solution techniques, and using computers and other electronic devices to analyze and solve natural scientific, social scientific and engineering problems.   Information engineering is an important underpinning for techniques used in information and computational science and there are many unresolved problems worth studying. The Proceedings of the 2nd International Conference on Information Engineering and Applications (IEA 2012), which was held in Chongqing, China, from October 26-28, 2012, discusses the most innovative research and developments including technical challenges and social, legal, political, and economic issues.   A forum for engineers and scientists in academia, industry, and government, the Proceedings of the 2nd International Conference on Information Engineering and Applications presents ideas, results, works in progress, and ...

  9. Application for certification 1993 model year heavy-duty diesel engines - Cummins Engine Company

    Energy Technology Data Exchange (ETDEWEB)


    Each year, each manufacturer of passenger cars, light-duty trucks, motorcycles, or heavy-duty engines submits to EPA an application for certification. In the application, the manufacturer gives a detailed technical description of the vehicles or engines he intends to market during the upcoming model year. These engineering data include explanations and/or drawings which describe engine/vehicle parameters such as basic engine design, fuel systems, ignition systems and exhaust and evaporative emission control systems. It also provides information on emission test procedures, service accumulation procedures, fuels to be used, and proposed maintenance requirements to be followed during testing. Section 16 of the application contains the results of emission testing, a statement or compliance to the regulations, production engine parameters, and a Summary Sheet Input Form on which issuance of a Certificate of Conformity is based.

  10. Teaching learning based optimization algorithm and its engineering applications

    CERN Document Server

    Rao, R Venkata


    Describing a new optimization algorithm, the “Teaching-Learning-Based Optimization (TLBO),” in a clear and lucid style, this book maximizes reader insights into how the TLBO algorithm can be used to solve continuous and discrete optimization problems involving single or multiple objectives. As the algorithm operates on the principle of teaching and learning, where teachers influence the quality of learners’ results, the elitist version of TLBO algorithm (ETLBO) is described along with applications of the TLBO algorithm in the fields of electrical engineering, mechanical design, thermal engineering, manufacturing engineering, civil engineering, structural engineering, computer engineering, electronics engineering, physics and biotechnology. The book offers a valuable resource for scientists, engineers and practitioners involved in the development and usage of advanced optimization algorithms.

  11. The study, design and simulation of a free piston Stirling engine linear alternatorThe study, design and simulation of a free piston Stirling engine linear alternator

    Directory of Open Access Journals (Sweden)

    Teodora Susana Oros


    Full Text Available This paper presents a study, design and simulation of a Free Piston Stirling Engine Linear Alternator. There are presented the main steps of the magnetic and electric calculations for a permanent magnet linear alternator of fixed coil and moving magnets type. Finally, a detailed thermal, mechanical and electrical model for a Stirling engine linear alternator have been made in SIMULINK simulation program. The linear alternator simulation model uses a controllable DC voltage which simulates the linear alternator combined with a rectifier, a variable load and a DC-DC converter, which compensates for the variable nature of Stirling engine operation, and ensures a constant voltage output regardless of the load.

  12. Piezoelectric materials and devices applications in engineering and medical sciences

    CERN Document Server

    Vijaya, M S


    Piezoelectric Materials and Devices: Applications in Engineering and Medical Sciences provides a complete overview of piezoelectric materials, covering all aspects of the materials starting from fundamental concepts. The treatment includes physics of piezoelectric materials, their characteristics and applications. The author uses simple language to explain the theory of piezoelectricity and introduce readers to the properties and design of different types of piezoelectric materials, such as those used in engineering and medical device applications.This book: Introduces various types of dielect

  13. A New Engineering Theory of Planar Bending and Applications. (United States)


    TR- Interim Scientific Report AA 12 1461 A NEW ENGINEERING THEORY OF PLANAR BENDING AND APPLICATIONS / I By Pappu L. N. Murthy and Lawrence W...Scientific Applications 6. PERFORMING ORG. REPORT NUMBERand Apiain 7. AUTHOR(*) S. CONTRACT OR GRANT NUMER4) Pappu L.N. Murthy and Lawrence W...APPLICATIONS Interim Scientific Report AFOSR Contract 81-0056 Pappu L.N. Murthy I and Lawrence W. Rehfield 2 school of Aerospace Engineering Georgia

  14. Parametric Optimization Through Numerical Simulation of VCR Diesel Engine (United States)

    Ganji, Prabhakara Rao; Mahmood, Al-Qarttani Abdulrahman Shakir; Kandula, Aasrith; Raju, Vysyaraju Rajesh Khana; Rao, Surapaneni Srinivasa


    In the present study, the Variable Compression Ratio (VCR) engine was analyzed numerically using CONVERGE™ Computational Fluid Dynamics code in order to optimize the design/operating parameters such as Compression Ratio (CR), Start of Injection (SOI) and Exhaust Gas Recirculation (EGR). VCR engine was run for 100 % load to test its performance and it was validated for standard configuration. Simulations were performed by varying the design/operating parameters such as CR (18-14), SOI (17°-26° bTDC) and EGR (0-15 %) at constant fuel injection pressure of 230 bar and speed of 1500 rpm. The effect of each of these parameters on pressure, oxides of nitrogen (NOx) and soot are presented. Finally, regression equations were developed for pressure, NOx and soot by using the simulation results. The regression equations were solved for multi objective criteria in order to reduce the NOx and soot while maintaining the baseline performance. The optimized configuration was tested for validation and found satisfactory.

  15. Enhancing food engineering education with interactive web-based simulations

    Directory of Open Access Journals (Sweden)

    Alexandros Koulouris


    Full Text Available In the traditional deductive approach in teaching any engineering topic, teachers would first expose students to the derivation of the equations that govern the behavior of a physical system and then demonstrate the use of equations through a limited number of textbook examples. This methodology, however, is rarely adequate to unmask the cause-effect and quantitative relationships between the system variables that the equations embody. Web-based simulation, which is the integration of simulation and internet technologies, has the potential to enhance the learning experience by offering an interactive and easily accessible platform for quick and effortless experimentation with physical phenomena.This paper presents the design and development of a web-based platform for teaching basic food engineering phenomena to food technology students. The platform contains a variety of modules (“virtual experiments” covering the topics of mass and energy balances, fluid mechanics and heat transfer. In this paper, the design and development of three modules for mass balances and heat transfer is presented. Each webpage representing an educational module has the following features: visualization of the studied phenomenon through graphs, charts or videos, computation through a mathematical model and experimentation.  The student is allowed to edit key parameters of the phenomenon and observe the effect of these changes on the outputs. Experimentation can be done in a free or guided fashion with a set of prefabricated examples that students can run and self-test their knowledge by answering multiple-choice questions.

  16. Computational modeling, optimization and manufacturing simulation of advanced engineering materials

    CERN Document Server


    This volume presents recent research work focused in the development of adequate theoretical and numerical formulations to describe the behavior of advanced engineering materials.  Particular emphasis is devoted to applications in the fields of biological tissues, phase changing and porous materials, polymers and to micro/nano scale modeling. Sensitivity analysis, gradient and non-gradient based optimization procedures are involved in many of the chapters, aiming at the solution of constitutive inverse problems and parameter identification. All these relevant topics are exposed by experienced international and inter institutional research teams resulting in a high level compilation. The book is a valuable research reference for scientists, senior undergraduate and graduate students, as well as for engineers acting in the area of computational material modeling.

  17. Vision and Displays for Military and Security Applications The Advanced Deployable Day/Night Simulation Project

    CERN Document Server

    Niall, Keith K


    Vision and Displays for Military and Security Applications presents recent advances in projection technologies and associated simulation technologies for military and security applications. Specifically, this book covers night vision simulation, semi-automated methods in photogrammetry, and the development and evaluation of high-resolution laser projection technologies for simulation. Topics covered include: advances in high-resolution projection, advances in image generation, geographic modeling, and LIDAR imaging, as well as human factors research for daylight simulation and for night vision devices. This title is ideal for optical engineers, simulator users and manufacturers, geomatics specialists, human factors researchers, and for engineers working with high-resolution display systems. It describes leading-edge methods for human factors research, and it describes the manufacture and evaluation of ultra-high resolution displays to provide unprecedented pixel density in visual simulation.

  18. Protein engineering and its applications in food industry. (United States)

    Kapoor, Swati; Rafiq, Aasima; Sharma, Savita


    Protein engineering is a young discipline that has been branched out from the field of genetic engineering. Protein engineering is based on the available knowledge about the proteins structure/function(s), tools/instruments, software, bioinformatics database, available cloned gene, knowledge about available protein, vectors, recombinant strains and other materials that could lead to change in the protein backbone. Protein produced properly from genetic engineering process means a protein that is able to fold correctly and to do particular function(s) efficiently even after being subjected to engineering practices. Protein is modified through its gene or chemically. However, modification of protein through gene is easier. There is no specific limitation of Protein Engineering tools; any technique that can lead to change the protein constituent of amino acid and result in the modification of protein structure/function is in the frame of Protein Engineering. Meanwhile, there are some common tools used to reach a specific target. More active industrial and pharmaceutical based proteins have been invented by the field of Protein Engineering to introduce new function as well as to change its interaction with surrounding environment. A variety of protein engineering applications have been reported in the literature. These applications range from biocatalysis for food and industry to environmental, medical and nanobiotechnology applications. Successful combinations of various protein engineering methods had led to successful results in food industries and have created a scope to maintain the quality of finished product after processing.

  19. Simulation Study (SimStudy): A Simulation Tool for Engineers and Mission Planners (United States)


    and build additional terrain databases . The SimStudy continues to be updated to mimic the ever-improving capabilities and demands of simulation...April 2009. 9. Stoliker, F.N., “ AGARD Flight Test Techniques Series, Volume 14: Introduction to Flight Test Engineering,” North Atlantic Treaty...Organization Advisory Group for Aerospace Research and Development, AGARD -AG_300 Vol. 14, Neuilly-Sur-Seine, France, September 1995. 14 LIST OF

  20. Constructing an Efficient Self-Tuning Aircraft Engine Model for Control and Health Management Applications (United States)

    Armstrong, Jeffrey B.; Simon, Donald L.


    Self-tuning aircraft engine models can be applied for control and health management applications. The self-tuning feature of these models minimizes the mismatch between any given engine and the underlying engineering model describing an engine family. This paper provides details of the construction of a self-tuning engine model centered on a piecewise linear Kalman filter design. Starting from a nonlinear transient aerothermal model, a piecewise linear representation is first extracted. The linearization procedure creates a database of trim vectors and state-space matrices that are subsequently scheduled for interpolation based on engine operating point. A series of steady-state Kalman gains can next be constructed from a reduced-order form of the piecewise linear model. Reduction of the piecewise linear model to an observable dimension with respect to available sensed engine measurements can be achieved using either a subset or an optimal linear combination of "health" parameters, which describe engine performance. The resulting piecewise linear Kalman filter is then implemented for faster-than-real-time processing of sensed engine measurements, generating outputs appropriate for trending engine performance, estimating both measured and unmeasured parameters for control purposes, and performing on-board gas-path fault diagnostics. Computational efficiency is achieved by designing multidimensional interpolation algorithms that exploit the shared scheduling of multiple trim vectors and system matrices. An example application illustrates the accuracy of a self-tuning piecewise linear Kalman filter model when applied to a nonlinear turbofan engine simulation. Additional discussions focus on the issue of transient response accuracy and the advantages of a piecewise linear Kalman filter in the context of validation and verification. The techniques described provide a framework for constructing efficient self-tuning aircraft engine models from complex nonlinear

  1. Reliability of ceramics for heat engine applications (United States)


    The advantages and disadvantages associated with the use of monolithic ceramics in heat engines are discussed. The principle gaps in the state of understanding of ceramic material, failure origins, nondestructive tests as well as life prediction are included.

  2. Simulation of Road Traffic Applying Model-Driven Engineering

    Directory of Open Access Journals (Sweden)



    Full Text Available Road traffic is an important phenomenon in modern societies. The study of its different aspects in the multiple scenarios where it happens is relevant for a huge number of problems. At the same time, its scale and complexity make it hard to study. Traffic simulations can alleviate these difficulties, simplifying the scenarios to consider and controlling their variables. However, their development also presents difficulties. The main ones come from the need to integrate the way of working of researchers and developers from multiple fields. Model-Driven Engineering (MDE addresses these problems using Modelling Languages (MLs and semi-automatic transformations to organise and describe the development, from requirements to code. This paper presents a domain-specific MDE framework for simulations of road traffic. It comprises an extensible ML, support tools, and development guidelines. The ML adopts an agent-based approach, which is focused on the roles of individuals in road traffic and their decision-making. A case study shows the process to model a traffic theory with the ML, and how to specialise that specification for an existing target platform and its simulations. The results are the basis for comparison with related work.

  3. Introduction to tissue engineering applications and challenges

    CERN Document Server

    Birla, Ravi


    Covering a progressive medical field, Tissue Engineering describes the innovative process of regenerating human cells to restore or establish normal function in defective organs. As pioneering individuals look ahead to the possibility of generating entire organ systems, students may turn to this textbook for a comprehensive understanding and preparation for the future of regenerative medicine. This book explains chemical stimulations, the bioengineering of specific organs, and treatment plans for chronic diseases. It is a must-read for tissue engineering students and practitioners.

  4. Acoustic emission testing: basics for research, applications in civil engineering

    National Research Council Canada - National Science Library

    Grosse, Christian U; Ohtsu, Masayasu


    ... methods observing a materials surface. There are many reports on successful AE applications in engineering at a broad variety of materials, material compositions and structures. Applications to many different materials are addressed in this book, but the success of these applications does not necessarily mean that the AET is easy to be applied....

  5. Development of teaching material to integrate GT-POWER into combustion courses for IC engine simulations. (United States)


    The main objective of this project was to develop instructional engineering projects that utilize the newly-offered PACE software GT-POWER for engine simulations in combustion-related courses at the Missouri University of Science and Technology. Stud...

  6. An introduction to network modeling and simulation for the practicing engineer

    CERN Document Server

    Burbank, Jack; Ward, Jon


    This book provides the practicing engineer with a concise listing of commercial and open-source modeling and simulation tools currently available including examples of implementing those tools for solving specific Modeling and Simulation examples. Instead of focusing on the underlying theory of Modeling and Simulation and fundamental building blocks for custom simulations, this book compares platforms used in practice, and gives rules enabling the practicing engineer to utilize available Modeling and Simulation tools. This book will contain insights regarding common pitfalls in network Modeling and Simulation and practical methods for working engineers.

  7. Expanding Applications of SERS through Versatile Nanomaterials Engineering (Postprint) (United States)


    directions We expect that advances in synthetic chemistry and materials engineering will continue to provide new directions for answer- ing chemical...biologically relevant molecules by SERS. 6. Conclusions Advances in synthetic chemistry and materials engineering have helped expand the applications of SERS...ROYAL SOCIETY OF CHEMISTRY (STINFO COPY) AIR FORCE RESEARCH LABORATORY MATERIALS AND MANUFACTURING DIRECTORATE WRIGHT-PATTERSON AIR FORCE BASE

  8. Organic Rankine Cycle and its application in renewable power engineering

    Directory of Open Access Journals (Sweden)

    G. V. Belov


    Full Text Available A considerable part of energy consumed in the world is thermal power that is produced due to burning of hydrocarbon fuels and as a result of controlled course of nuclear reactions. Thus rather large part of thermal power is used ultrainefficiently, often simply dissipates in environment. The rise in prices for energy compels to use low-grade one to be released in large quantities in environment. To utilize the low-grade energy Renkin's cycle with with alternative working bodies is often applied. The corresponding cycle was called Renkin's organic cycle (ROC. A substance with lower boiling temperature, than that of water is used in ROC as a working body to utilize low-grade energy.The review of literature shows that thrust on power sector related to utilization of residual heat (thermal waste and use of alternative energy sources, recently, intensively develops. However there is, essentially, a lack of publications on this subject in Russian. The objective of given article is to analyse modern sources of information (mainly, foreign ones which consider various aspects of ROC and its application potential in alternative power engineering. The article focuses much attention on the choice of ROC working body. It presents a list of main requirements for a working body. The article studies the matters of ROC simulation.It is shown that ROC application enables using the low-grade power of exhaust gases, geothermal sources, other thermal streams with rather low temperature. Integration of ROC with ICE (internal combustion engine is in position to increase an efficiency of used fuel energy and to reduce amount of toxic impurity in exhaust gases. Essential influence of working body properties on its characteristics of ROC is noted.

  9. Institute for Computer Applications in Science and Engineering (ICASE) (United States)


    Research conducted at the Institute for Computer Applications in Science and Engineering in applied mathematics, numerical analysis and computer science during the period April 1, 1983 through September 30, 1983 is summarized.

  10. application of used engine oil on of used engine oil in soil on of ...

    African Journals Online (AJOL)


    applicability of used engine oil used engine oil ordinary Portland ordinary Portland cement (OPC) stabiliz. Sand (SC) according to the unified soil classification according to the unified soil classification soaked and unsoaked CBR soaked and unsoaked CBR tests, X-ray fluorescence ray fluorescence general reduction in the ...

  11. International Conference on Soft Computing Techniques and Engineering Application

    CERN Document Server

    Li, Xiaolong


    The main objective of ICSCTEA 2013 is to provide a platform for researchers, engineers and academicians from all over the world to present their research results and development activities in soft computing techniques and engineering application. This conference provides opportunities for them to exchange new ideas and application experiences face to face, to establish business or research relations and to find global partners for future collaboration.

  12. Nonlinear optimization in electrical engineering with applications in Matlab

    CERN Document Server

    Bakr, Mohamed


    Nonlinear Optimization in Electrical Engineering with Applications in MATLAB® provides an introductory course on nonlinear optimization in electrical engineering, with a focus on applications such as the design of electric, microwave, and photonic circuits, wireless communications, and digital filter design. Basic concepts are introduced using a step-by-step approach and illustrated with MATLAB® codes that the reader can use and adapt. Topics covered include: classical optimization methods; one dimensional optimization; unconstrained and constrained optimization; global optimization; space map

  13. Centaur engine gimbal friction characteristics under simulated thrust load (United States)

    Askew, J. W.


    An investigation was performed to determine the friction characteristics of the engine gimbal system of the Centaur upper stage rocket. Because the Centaur requires low-gain autopilots in order to meet all stability requirements for some configurations, control performance (response to transients and limit-cycle amplitudes) depends highly on these friction characteristics. Forces required to rotate the Centaur engine gimbal system were measured under a simulated thrust load of 66,723 N (15,000 lb) and in an altitude/thermal environment. A series of tests was performed at three test conditions; ambient temperature and pressure, ambient temperature and vacuum, and cryogenic temperature and vacuum. Gimbal rotation was controlled, and tests were performed in which rotation amplitude and frequency were varied by using triangular and sinusoidal waveforms. Test data revealed an elastic characteristic of the gimbal, independent of the input signal, which was evident prior to true gimbal sliding. The torque required to initiate gimbal sliding was found to decrease when both pressure and temperature decreased. Results from the low amplitude and low frequency data are currently being used in mathematically modeling the gimbal friction characteristics for Centaur autopilot performance studies.

  14. Simulation and testing of new control methods for achieving low emissions in gas turbine engines

    Energy Technology Data Exchange (ETDEWEB)

    Boyce, P.M.


    In the past few years, development of clean burning land-based industrial gas turbines have been the focus for many manufacturers. This effort lead to the development of the LM6000 dry low emission engine. As a part of the control system, a real time mathematical model of the engine was included. This model is used to control the air and fuel low paths to the engine`s new combustor. A real time simulator was needed to simulate the control system hardware and engine. A brief discussion and some basic concepts of the combustor, along with a full discussion on the development of the real time simulator, follows in this paper.

  15. Ceramic applications in turbine engines. [for automotive application (United States)

    Byrd, J. A.; Helms, H. E.


    In the past the potential of vehicular gas engines could not be realized because component materials served to limit the turbine operating temperature, thereby restricting fuel economy and initial cost. It was, therefore, not possible for the vehicular gas turbine to compete with more conventional engines. The emergence of low-cost, high-temperature ceramic components has the potential to reverse this situation. For example, the Allison GT404 engine, operating with ceramic components at turbine inlet temperatures up to 2350 F to 2500 F, has the potential of a fuel economy which is better than that of current Diesel engines. The Allison AGT100 engine operating with ceramic components offers the possibility of a 30% improvement in fuel economy over 1985 spark ignition engines. The materials considered for an employment in the ceramic components include silicon carbide, silicon nitride, aluminum silicate, and lithium aluminum silicate.

  16. Engineering applications of metaheuristics: an introduction (United States)

    Oliva, Diego; Hinojosa, Salvador; Demeshko, M. V.


    Metaheuristic algorithms are important tools that in recent years have been used extensively in several fields. In engineering, there is a big amount of problems that can be solved from an optimization point of view. This paper is an introduction of how metaheuristics can be used to solve complex problems of engineering. Their use produces accurate results in problems that are computationally expensive. Experimental results support the performance obtained by the selected algorithms in such specific problems as digital filter design, image processing and solar cells design.

  17. Key applications of plant metabolic engineering.

    Directory of Open Access Journals (Sweden)

    Warren Lau


    Full Text Available Great strides have been made in plant metabolic engineering over the last two decades, with notable success stories including Golden rice. Here, we discuss the field's progress in addressing four long-standing challenges: creating plants that satisfy their own nitrogen requirement, so reducing or eliminating the need for nitrogen fertilizer; enhancing the nutrient content of crop plants; engineering biofuel feed stocks that harbor easy-to-access fermentable saccharides by incorporating self-destructing lignin; and increasing photosynthetic efficiency. We also look to the future at emerging areas of research in this field.

  18. The application of reaction engineering to biocatalysis

    DEFF Research Database (Denmark)

    Ringborg, Rolf Hoffmeyer; Woodley, John


    outline the benefits of reaction engineering in this development process, with particular emphasis of reaction kinetics. Future research needs to focus on rapid methods to collect such data at sufficient accuracy that it can be used forthe effective design of new biocatalytic processes.......Biocatalysis is a growing area of synthetic and process chemistry with the ability to deliver not only improved processes for the synthesis of existing compounds, but also new routes to new compounds. In order to assess the many options and strategies available to an engineer developing a new...

  19. Engineering porous materials for fuel cell applications. (United States)

    Brandon, N P; Brett, D J


    Porous materials play an important role in fuel cell engineering. For example, they are used to support delicate electrolyte membranes, where mechanical integrity and effective diffusivity to fuel gases is critical; they are used as gas diffusion layers, where electronic conductivity and permeability to both gas and water is critical; and they are used to construct fuel cell electrodes, where an optimum combination of ionic conductivity, electronic conductivity, porosity and catalyst distribution is critical. The paper will discuss these characteristics, and introduce the materials and processing methods used to engineer porous materials within two of the leading fuel cell variants, the solid oxide fuel cell and the polymer electrolyte membrane fuel cell.

  20. Fundamentals of reliability engineering applications in multistage interconnection networks

    CERN Document Server

    Gunawan, Indra


    This book presents fundamentals of reliability engineering with its applications in evaluating reliability of multistage interconnection networks. In the first part of the book, it introduces the concept of reliability engineering, elements of probability theory, probability distributions, availability and data analysis.  The second part of the book provides an overview of parallel/distributed computing, network design considerations, and more.  The book covers a comprehensive reliability engineering methods and its practical aspects in the interconnection network systems. Students, engineers, researchers, managers will find this book as a valuable reference source.

  1. Applications of Statistics and Probability in Civil Engineering

    DEFF Research Database (Denmark)

    Faber, Michael Havbro

    contains the proceedings of the 11th International Conference on Applications of Statistics and Probability in Civil Engineering (ICASP11, Zürich, Switzerland, 1-4 August 2011). The book focuses not only on the more traditional technical issues, but also emphasizes the societal context...... and reliability in engineering; to professionals and engineers, including insurance and consulting companies working with natural hazards, design, operation and maintenance of civil engineering and industrial facilities; and to decision makers and professionals in the public sector, including nongovernmental...

  2. Application for Simulating Gyro-Compass Behavior

    Directory of Open Access Journals (Sweden)

    Jaskólski Krzysztof


    Full Text Available Resolution of International Maritime Organization (IMO Res. A.424 (XI, International Convention for the Safety of Life at Sea (SOLAS V/19.2.5 and consequently ‘Provisions Survey of Ships Marine’, part V, contained in the Polish Register of Shipping impose an obligation to fit ships with gyro-compass as one of the most complex marine equipment has found in the curricula of seafarers at the operational level (IMO Model Course 7.03. Curriculum involves the use real navigation devices. In addition, the adaptation of teaching facilities to meet the needs of the training process often requires the development of educational aids in the form of simulators and applications that represent the construction and operation of navigation devices. The article presents possibilities of the application - gyro-compass simulator developed for the requirements of the Institute of Navigation and Maritime Hydrography PNA. Among others, the program is used to simulate the conditions in which you can expect the occurrence of different types of gyro-compass deviation. Designed software is expected to improve the educational process, to help the students assimilate the content of the curriculum in the field of classic gyro-compasses and familiarize trainees with static and dynamic errors occurring with the change of operating conditions.

  3. Statistics and probability with applications for engineers and scientists

    CERN Document Server

    Gupta, Bhisham C


    Introducing the tools of statistics and probability from the ground up An understanding of statistical tools is essential for engineers and scientists who often need to deal with data analysis over the course of their work. Statistics and Probability with Applications for Engineers and Scientists walks readers through a wide range of popular statistical techniques, explaining step-by-step how to generate, analyze, and interpret data for diverse applications in engineering and the natural sciences. Unique among books of this kind, Statistics and Prob

  4. Applications of yeast surface display for protein engineering (United States)

    Cherf, Gerald M.; Cochran, Jennifer R.


    The method of displaying recombinant proteins on the surface of Saccharomyces cerevisiae via genetic fusion to an abundant cell wall protein, a technology known as yeast surface display, or simply, yeast display, has become a valuable protein engineering tool for a broad spectrum of biotechnology and biomedical applications. This review focuses on the use of yeast display for engineering protein affinity, stability, and enzymatic activity. Strategies and examples for each protein engineering goal are discussed. Additional applications of yeast display are also briefly presented, including protein epitope mapping, identification of protein-protein interactions, and uses of displayed proteins in industry and medicine. PMID:26060074

  5. Value Engineering: An Application to Computer Software (United States)


    software to effectively implement VE in software acquisition. To add to this problem, the DOD Value Engineering program as a whole has had a history ...of VE in sortware acquisitionfdevelopment (ie. educacion , award programs, designate Govt. savings for use in 77 generating additional savings

  6. Computer Applications in Production and Engineering

    DEFF Research Database (Denmark)

    Sørensen, Torben


    into an integrated manufacturing unit. Such units are known as Computer Integrated Manufacturing and Engineering (CIME) systems.The basic concept in CIME is to share and reuse information between the different computer based subsystems. Consequently, for the integration purposes, the CIME systems are highly...

  7. Engineering applications of pneumatics and hydraulics

    CERN Document Server

    Turner, Ian C


    Assuming only the most basic knowledge of the physics of fluids, this book aims to equip the reader with a sound understanding of fluid power systems and their uses in practical engineering. In line with the strongly practical bias of the book, maintenance and trouble-shooting are covered, with particular emphasis on safety systems and regulations.

  8. Confocal Raman Microscopy; applications in tissue engineering

    NARCIS (Netherlands)

    van Apeldoorn, Aart A.


    This dissertation describes the use of confocal Raman microscopy and spectroscopy in the field of tissue engineering. Moreover, it describes the combination of two already existing technologies, namely scanning electron microscopy and confocal Raman spectroscopy in one apparatus for the enhancement

  9. Advances in Industrial Engineering Applications and Pratice

    DEFF Research Database (Denmark)

    Sørensen, Torben


    are known as Computer Integrated Manufacturing and Engineering (CIME) systems. The basic concept in CIME is to share and reuse information between the different computer based subsystems. Consequently, for the integration purposes, the CIME systems are highly dependent on reliable product model interfaces...

  10. Advances in Computer Science, Engineering & Applications : Proceedings of the Second International Conference on Computer Science, Engineering & Applications

    CERN Document Server

    Zizka, Jan; Nagamalai, Dhinaharan


    The International conference series on Computer Science, Engineering & Applications (ICCSEA) aims to bring together researchers and practitioners from academia and industry to focus on understanding computer science, engineering and applications and to establish new collaborations in these areas. The Second International Conference on Computer Science, Engineering & Applications (ICCSEA-2012), held in Delhi, India, during May 25-27, 2012 attracted many local and international delegates, presenting a balanced mixture of  intellect and research both from the East and from the West. Upon a strenuous peer-review process the best submissions were selected leading to an exciting, rich and a high quality technical conference program, which featured high-impact presentations in the latest developments of various areas of computer science, engineering and applications research.  

  11. Advances in Computer Science, Engineering & Applications : Proceedings of the Second International Conference on Computer Science, Engineering & Applications

    CERN Document Server

    Zizka, Jan; Nagamalai, Dhinaharan


    The International conference series on Computer Science, Engineering & Applications (ICCSEA) aims to bring together researchers and practitioners from academia and industry to focus on understanding computer science, engineering and applications and to establish new collaborations in these areas. The Second International Conference on Computer Science, Engineering & Applications (ICCSEA-2012), held in Delhi, India, during May 25-27, 2012 attracted many local and international delegates, presenting a balanced mixture of  intellect and research both from the East and from the West. Upon a strenuous peer-review process the best submissions were selected leading to an exciting, rich and a high quality technical conference program, which featured high-impact presentations in the latest developments of various areas of computer science, engineering and applications research.

  12. Quasi-2D Unsteady Flow Solver Module for Rocket Engine and Propulsion System Simulations

    National Research Council Canada - National Science Library

    Campell, Bryan T; Davis, Roger L


    .... The solver is targeted to the commercial dynamic simulation software package Simulink(Registered) for integration into a larger suite of modules developed for simulating rocket engines and propulsion systems...

  13. Establishing a "Centre for Engineering Experimentation and Design Simulation": A Step towards Restructuring Engineering Education in India (United States)

    Venkateswarlu, P.


    Reforms in undergraduate engineering curriculum to produce engineers with entrepreneurial skills should address real-world problems relevant to industry and society with active industry support. Technology-assisted, hands-on projects involving experimentation, design simulation and prototyping will transform graduates into professionals with…

  14. Applications of hybrid and digital computation methods in aerospace-related sciences and engineering. [problem solving methods at the University of Houston (United States)

    Huang, C. J.; Motard, R. L.


    The computing equipment in the engineering systems simulation laboratory of the Houston University Cullen College of Engineering is described and its advantages are summarized. The application of computer techniques in aerospace-related research psychology and in chemical, civil, electrical, industrial, and mechanical engineering is described in abstracts of 84 individual projects and in reprints of published reports. Research supports programs in acoustics, energy technology, systems engineering, and environment management as well as aerospace engineering.

  15. Hollow fiber bioreactor technology for tissue engineering applications. (United States)

    Eghbali, Hadis; Nava, Michele M; Mohebbi-Kalhori, Davod; Raimondi, Manuela T


    Hollow fiber bioreactors are the focus of scientific research aiming to mimic physiological vascular networks and engineer organs and tissues in vitro. The reason for this lies in the interesting features of this bioreactor type, including excellent mass transport properties. Indeed, hollow fiber bioreactors allow limitations to be overcome in nutrient transport by diffusion, which is often an obstacle to engineer sizable constructs in vitro. This work reviews the existing literature relevant to hollow fiber bioreactors in organ and tissue engineering applications. To this purpose, we first classify the hollow fiber bioreactors into 2 categories: cylindrical and rectangular. For each category, we summarize their main applications both at the tissue and at the organ level, focusing on experimental models and computational studies as predictive tools for designing innovative, dynamic culture systems. Finally, we discuss future perspectives on hollow fiber bioreactors as in vitro models for tissue and organ engineering applications.

  16. Multicomponent and multiscale systems theory, methods, and applications in engineering

    CERN Document Server

    Geiser, Juergen


    This book examines the latest research results from combined multi-component and multi-scale explorations. It provides theory, considers underlying numerical methods, and presents brilliant computational experimentation. Engineering computations featured in this monograph further offer particular interest to many researchers, engineers, and computational scientists working in frontier modeling and applications of multicomponent and multiscale problems. Professor Geiser gives specific attention to the aspects of decomposing and splitting delicate structures and controlling decomposition and the rationale behind many important applications of multi-component and multi-scale analysis. Multicomponent and Multiscale Systems: Theory, Methods, and Applications in Engineering also considers the question of why iterative methods can be powerful and more appropriate for well-balanced multiscale and multicomponent coupled nonlinear problems. The book is ideal for engineers and scientists working in theoretical and a...

  17. Weighted Ensemble Simulation: Review of Methodology, Applications, and Software. (United States)

    Zuckerman, Daniel M; Chong, Lillian T


    The weighted ensemble (WE) methodology orchestrates quasi-independent parallel simulations run with intermittent communication that can enhance sampling of rare events such as protein conformational changes, folding, and binding. The WE strategy can achieve superlinear scaling-the unbiased estimation of key observables such as rate constants and equilibrium state populations to greater precision than would be possible with ordinary parallel simulation. WE software can be used to control any dynamics engine, such as standard molecular dynamics and cell-modeling packages. This article reviews the theoretical basis of WE and goes on to describe successful applications to a number of complex biological processes-protein conformational transitions, (un)binding, and assembly processes, as well as cell-scale processes in systems biology. We furthermore discuss the challenges that need to be overcome in the next phase of WE methodological development. Overall, the combined advances in WE methodology and software have enabled the simulation of long-timescale processes that would otherwise not be practical on typical computing resources using standard simulation.

  18. Growing tissues in real and simulated microgravity: new methods for tissue engineering. (United States)

    Grimm, Daniela; Wehland, Markus; Pietsch, Jessica; Aleshcheva, Ganna; Wise, Petra; van Loon, Jack; Ulbrich, Claudia; Magnusson, Nils E; Infanger, Manfred; Bauer, Johann


    Tissue engineering in simulated (s-) and real microgravity (r-μg) is currently a topic in Space medicine contributing to biomedical sciences and their applications on Earth. The principal aim of this review is to highlight the advances and accomplishments in the field of tissue engineering that could be achieved by culturing cells in Space or by devices created to simulate microgravity on Earth. Understanding the biology of three-dimensional (3D) multicellular structures is very important for a more complete appreciation of in vivo tissue function and advancing in vitro tissue engineering efforts. Various cells exposed to r-μg in Space or to s-μg created by a random positioning machine, a 2D-clinostat, or a rotating wall vessel bioreactor grew in the form of 3D tissues. Hence, these methods represent a new strategy for tissue engineering of a variety of tissues, such as regenerated cartilage, artificial vessel constructs, and other organ tissues as well as multicellular cancer spheroids. These aggregates are used to study molecular mechanisms involved in angiogenesis, cancer development, and biology and for pharmacological testing of, for example, chemotherapeutic drugs or inhibitors of neoangiogenesis. Moreover, they are useful for studying multicellular responses in toxicology and radiation biology, or for performing coculture experiments. The future will show whether these tissue-engineered constructs can be used for medical transplantations. Unveiling the mechanisms of microgravity-dependent molecular and cellular changes is an up-to-date requirement for improving Space medicine and developing new treatment strategies that can be translated to in vivo models while reducing the use of laboratory animals.

  19. 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications

    CERN Document Server

    Koziel, Slawomir; Kacprzyk, Janusz; Leifsson, Leifur; Ören, Tuncer


    This book includes extended and revised versions of a set of selected papers from the 3rd International Conference on Simulation and Modeling Methodologies, Technologies and Applications (SIMULTECH 2013) which was co-organized by the Reykjavik University (RU) and sponsored by the Institute for Systems and Technologies of Information, Control and Communication (INSTICC). SIMULTECH 2013 was held in cooperation with the ACM SIGSIM - Special Interest Group (SIG) on SImulation and Modeling (SIM), Movimento Italiano Modellazione e Simulazione (MIMOS) and AIS Special Interest Group on Modeling and Simulation (AIS SIGMAS) and technically co-sponsored by the Society for Modeling & Simulation International (SCS), Liophant Simulation, Simulation Team and International Federation for Information Processing (IFIP). This proceedings brings together researchers, engineers, applied mathematicians and practitioners working in the advances and applications in the field of system simulation.

  20. Engineering artificial machines from designable DNA materials for biomedical applications. (United States)

    Qi, Hao; Huang, Guoyou; Han, Yulong; Zhang, Xiaohui; Li, Yuhui; Pingguan-Murphy, Belinda; Lu, Tian Jian; Xu, Feng; Wang, Lin


    Deoxyribonucleic acid (DNA) emerges as building bricks for the fabrication of nanostructure with complete artificial architecture and geometry. The amazing ability of DNA in building two- and three-dimensional structures raises the possibility of developing smart nanomachines with versatile controllability for various applications. Here, we overviewed the recent progresses in engineering DNA machines for specific bioengineering and biomedical applications.

  1. Rubble-pile Simulations Using The Open Dynamics Engine (United States)

    Korycansky, Donald; Asphaug, E.


    We describe a series of calculations of low-speed collisions of km-scale rubble piles (i.e. asteroids or planetesimals), similar to previous work (Korycansky and Asphaug 2006). The rubble piles are aggregates of polyhedra held together by gravity and friction. Collision velocities are typically of order 1 to 100 m/sec.In this work we make use of a so-called "physics engine" to solve the equations of rigid-body motion and collisions of the polyhedra. Such code libraries have been primarily developed for computer simulations and games. The chief advantage of these libraries is the inclusion of sophisticated algorithms for collision detection, which we have found to be the main computational bottleneck in our calculations. The package we have used is the Open Dynamics Engine, a freely available open-source library ( It solves the equations of motion to first-order accuracy in time and utilizes a fast algorithm for collision detection. We have found a factor of approximately 30 speed-up for our calculations, allowing the exploration of a much larger range of parameter space and the running of multiple calculations in order to sample the stochasticity of the results. For the calculations we report on here, the basic model is the collision of an impactor in the range 0.1--1 km in diameter with a target of 1 km diameter.argets are modeled with 1000 polyhedral elements and impactors modeled with 1 to 1000 elements depending on mass. Collisions of objects with both equal-mass elements, and elements chosen from a power-law distribution, are studied. We concentrate on determining the energy required for catastrophic disruption (Q*D) as a function of impactor/target mass atio and impactor parameter for off-center collisions. This work has been supported by NASA Planetary Geology and Geophysics Program grant NNX07AQ04G.

  2. Microwave RF antennas and circuits nonlinearity applications in engineering

    CERN Document Server

    Aluf, Ofer


    This book describes a new concept for analyzing RF/microwave circuits, which includes RF/microwave antennas. The book is unique in its emphasis on practical and innovative microwave RF engineering applications. The analysis is based on nonlinear dynamics and chaos models and shows comprehensive benefits and results. All conceptual RF microwave circuits and antennas are innovative and can be broadly implemented in engineering applications. Given the dynamics of RF microwave circuits and antennas, they are suitable for use in a broad range of applications. The book presents analytical methods for microwave RF antennas and circuit analysis, concrete examples, and geometric examples. The analysis is developed systematically, starting with basic differential equations and their bifurcations, and subsequently moving on to fixed point analysis, limit cycles and their bifurcations. Engineering applications include microwave RF circuits and antennas in a variety of topological structures, RFID ICs and antennas, micros...

  3. Multiscale ensemble filtering for reservoir engineering applications

    NARCIS (Netherlands)

    Lawniczak, W.; Hanea, R.G.; Heemink, A.; McLaughlin, D.


    Reservoir management requires periodic updates of the simulation models using the production data available over time. Traditionally, validation of reservoir models with production data is done using a history matching process. Uncertainties in the data, as well as in the model, lead to a nonunique

  4. SIMULATE-3 K coupled code applications

    Energy Technology Data Exchange (ETDEWEB)

    Joensson, Christian [Studsvik Scandpower AB, Vaesteraas (Sweden); Grandi, Gerardo; Judd, Jerry [Studsvik Scandpower Inc., Idaho Falls, ID (United States)


    This paper describes the coupled code system TRACE/SIMULATE-3 K/VIPRE and the application of this code system to the OECD PWR Main Steam Line Break. A short description is given for the application of the coupled system to analyze DNBR and the flexibility the system creates for the user. This includes the possibility to compare and evaluate the result with the TRACE/SIMULATE-3K (S3K) coupled code, the S3K standalone code (core calculation) as well as performing single-channel calculations with S3K and VIPRE. This is the typical separate-effect-analyses required for advanced calculations in order to develop methodologies to be used for safety analyses in general. The models and methods of the code systems are presented. The outline represents the analysis approach starting with the coupled code system, reactor and core model calculation (TRACE/S3K). This is followed by a more detailed core evaluation (S3K standalone) and finally a very detailed thermal-hydraulic investigation of the hot pin condition (VIPRE).

  5. Automatic differentiation tools in the dynamic simulation of chemical engineering processes

    Directory of Open Access Journals (Sweden)

    Castro M.C.


    Full Text Available Automatic Differentiation is a relatively recent technique developed for the differentiation of functions applicable directly to the source code to compute the function written in standard programming languages. That technique permits the automatization of the differentiation step, crucial for dynamic simulation and optimization of processes. The values for the derivatives obtained with AD are exact (to roundoff. The theoretical exactness of the AD comes from the fact that it uses the same rules of differentiation as in differential calculus, but these rules are applied to an algorithmic specification of the function rather than to a formula. The main purpose of this contribution is to discuss the impact of Automatic Differentiation in the field of dynamic simulation of chemical engineering processes. The influence of the differentiation technique on the behavior of the integration code, the performance of the generated code and the incorporation of AD tools in consistent initialization tools are discussed from the viewpoint of dynamic simulation of typical models in chemical engineering.

  6. Application Model for a Stirling Engine Micro-Generation System in Caravans in Different European Locations

    Directory of Open Access Journals (Sweden)

    Carlos Ulloa


    Full Text Available This article describes a simple model obtained from a commercial Stirling engine and used for heating a caravan. The Stirling engine has been tested in the lab under different electrical load conditions, and the operating points obtained are presented. As an application of the model, a series of transient simulations was performed using TRNSYS. During these simulations, the caravan is traveling throughout the day and is stationary at night. Therefore, during the night-time hours, the heating system is turned on by means of the Stirling engine. The study was performed for each month of the year in different European cities. The different heating demand profiles for different cities induce variation in the electricity production, as it has been assumed that electricity is only generated when the thermal demand requires the operation of the Stirling system. As a result, a comparison of the expected power generation in different European cities is presented.

  7. Protein engineering of enzymes for process applications

    DEFF Research Database (Denmark)

    Woodley, John M


    Scientific progress in the field of enzyme modification today enables the opportunity to tune a given biocatalyst for a specific industrial application. Much work has been focused on extending the substrate repertoire and altering selectivity. Nevertheless, it is clear that many new forthcoming...... opportunities will be targeted on modification to enable process application. This article discusses the challenges involved in enzyme modification focused on process requirements, such as the need to fulfill reaction thermodynamics, specific activity under the required conditions, kinetics at required...

  8. Engineering

    National Research Council Canada - National Science Library

    Includes papers in the following fields: Aerospace Engineering, Agricultural Engineering, Chemical Engineering, Civil Engineering, Electrical Engineering, Environmental Engineering, Industrial Engineering, Materials Engineering, Mechanical...

  9. Applications of MEMS technologies in tissue engineering. (United States)

    Puleo, Christopher M; Yeh, Hsin-Chih; Wang, Tza-Huei


    The success of therapeutic strategies within the fields of regenerative medicine, including tissue engineering, biomaterials engineering, and cell and tissue transplantation science, relies on researchers' understanding of the complex cellular microenvironments that occur within functional tissue. Microfabricated biomedical platforms provide tools for researchers to study cellular response to various stimuli with micro- and nanoscale spatial control. Initial studies utilizing relatively passive means of microenvironmental control have provided the fundamental knowledge required to begin to design microculture platforms that closely mimic these biological systems. In this review, we discuss second-generation cell and tissue culture platforms that utilize active components, borrowed from work in the development of microelectromechanical systems (MEMS). These microsystems offer the unprecedented opportunity to fabricate culture platforms designed to match tissue-specific growth parameters. In addition, the adoption of MEMS components opens up the door for future integration with the burgeoning field of microanalytical systems, providing analytical platforms that retain the sensitivity and resolution required within low-volume, microfluidic culture technologies.

  10. Potential applications of skip SMV with thrust engine (United States)

    Wang, Weilin; Savvaris, Al


    This paper investigates the potential applications of Space Maneuver Vehicles (SMV) with skip trajectory. Due to soaring space operations over the past decades, the risk of space debris has considerably increased such as collision risks with space asset, human property on ground and even aviation. Many active debris removal methods have been investigated and in this paper, a debris remediation method is first proposed based on skip SMV. The key point is to perform controlled re-entry. These vehicles are expected to achieve a trans-atmospheric maneuver with thrust engine. If debris is released at altitude below 80 km, debris could be captured by the atmosphere drag force and re-entry interface prediction accuracy is improved. Moreover if the debris is released in a cargo at a much lower altitude, this technique protects high value space asset from break up by the atmosphere and improves landing accuracy. To demonstrate the feasibility of this concept, the present paper presents the simulation results for two specific mission profiles: (1) descent to predetermined altitude; (2) descent to predetermined point (altitude, longitude and latitude). The evolutionary collocation method is adopted for skip trajectory optimization due to its global optimality and high-accuracy. This method is actually a two-step optimization approach based on the heuristic algorithm and the collocation method. The optimal-control problem is transformed into a nonlinear programming problem (NLP) which can be efficiently and accurately solved by the sequential quadratic programming (SQP) procedure. However, such a method is sensitive to initial values. To reduce the sensitivity problem, genetic algorithm (GA) is adopted to refine the grids and provide near optimum initial values. By comparing the simulation data from different scenarios, it is found that skip SMV is feasible in active debris removal and the evolutionary collocation method gives a truthful re-entry trajectory that satisfies the

  11. Development of Kinetic Mechanisms for Next-Generation Fuels and CFD Simulation of Advanced Combustion Engines

    Energy Technology Data Exchange (ETDEWEB)

    Pitz, William J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); McNenly, Matt J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Whitesides, Russell [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mehl, Marco [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Killingsworth, Nick J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Westbrook, Charles K. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    Predictive chemical kinetic models are needed to represent next-generation fuel components and their mixtures with conventional gasoline and diesel fuels. These kinetic models will allow the prediction of the effect of alternative fuel blends in CFD simulations of advanced spark-ignition and compression-ignition engines. Enabled by kinetic models, CFD simulations can be used to optimize fuel formulations for advanced combustion engines so that maximum engine efficiency, fossil fuel displacement goals, and low pollutant emission goals can be achieved.

  12. Performance, Applications, and Analysis of Rotating Detonation Engine Technologies (Preprint) (United States)


    Scott W. Theuerkauf, and Frederick R. Schauer Combustion Branch Turbine Engine Division Matthew L. Fotia, Andrew G. Naples, Christopher A...5c. PROGRAM ELEMENT NUMBER 62203F 6. AUTHOR(S) Brent A. Rankin, Scott W. Theuerkauf, and Frederick R. Schauer (AFRL/RQTC) Matthew L. Fotia, Andrew...unlimited. Performance, Application, and Analysis of Rotating Detonation Engine Technologies Brent A. Rankin1, Scott W. Theuerkauf2, and Frederick R

  13. Advanced materials and protective coatings in aero-engines application


    M. Hetmańczyk; L. Swadźba; B. Mendala


    Purpose: The following article demonstrates the characteristics of the materials applied as parts of aircraft engine turbines and the stationary gas turbines. The principal technologies for manufacturing the heat resistant coatings and the erosion and corrosion resistant coatings were characterized. Sample applications for the aforementioned coatings are presented: on turbine blades, compressor blades and on parts of combustion chambers of aircraft engines.Design/methodology/approach: The nic...

  14. Laser engine simulation using pressure based Navier-Stokes solver (United States)

    Youssef, Hazim Saad


    Analysis of the flow field in a laser engine represents a difficult computational problem involving combinations of complex physical and gas-dynamical processes. Following a brief discussion of these processes a calculation procedure using primitive variables formulation on a nonstaggered grid system is introduced. Based on this procedure, a pressure based Navier-Stokes solver (PBNS) is developed using a generalized curvilinear coordinate system. The solver is first tested in application to a subsonic compressible flow over an insulated flat plate and to a flow in an axisymmetric converging-diverging nozzle. Next, the PBNS code is used to analyze the flowfield and performance of a laser thruster. The physical/numerical model includes the geometric ray tracing for the laser beam, beam power absorption, plasma radiation losses, and plasma thermophysical and optical properties. Equilibrium hydrogen is used as a flowing gas and its properties are calculated using the Hydrogen Properties Calculation (HPC) based on the methods of statistical thermodynamics. Two thrustor configurations, two laser types (CO2 and iodide), various laser power levels, and various injection conditions are tested. The results of these tests include the temperature, pressure, velocity, and Mach number contours, as well as tables of the laser beam power absorbed, radiation losses to the thrustor walls, thrust level, and specific impulse. The maximum specific impulse obtained in these tests is 1537 sec for a CO2 laser thruster and 827 sec for an iodide laser thruster. Up to 100% power absorption can be achieved; however, radiation losses from the hot plasma are quite high disallowing a full conversion of the absorbed power into the thermal energy of the propellant. The PBNS code can be used to study the effects of various design parameters on the performance of a laser thruster and provide guidelines for the preliminary design of a laser engine.

  15. Applicability of advanced automotive heat engines to solar thermal power (United States)

    Beremand, D. G.; Evans, D. G.; Alger, D. L.


    The requirements of a solar thermal power system are reviewed and compared with the predicted characteristics of automobile engines under development. A good match is found in terms of power level and efficiency when the automobile engines, designed for maximum powers of 65-100 kW (87 to 133 hp) are operated to the nominal 20-40 kW electric output requirement of the solar thermal application. At these reduced power levels it appears that the automotive gas turbine and Stirling engines have the potential to deliver the 40+ percent efficiency goal of the solar thermal program.

  16. Towards evolution-guided microbial engineering - tools development and applications

    DEFF Research Database (Denmark)

    Genee, Hans Jasper

    -performing microorganisms.However, an insufficient understanding of biological complexity currentlyrenders strict forward engineering approaches inadequate. Our success forthe development of useful biological systems is therefore largelydetermined by our abilities to generate microbial diversity and evaluate itsphenotypic...... performance at large-scale.In this thesis I report the development of a number of novel tools -experimental as well as computational - that aim to accelerate theconstruction of new microbial phenotypes and functionally evaluate theirperformance in ultra high-throughput. At the very core of the thesis...... for microbial engineering anddemonstrates direct applications to gene discovery, protein engineering andcell factory development....

  17. Building GIS applications in an engineering environment

    Energy Technology Data Exchange (ETDEWEB)

    Schaaf, F. van der; Volkert, J. [BSC/Cullinan Associates, Boston, MA (United States)


    The application of geographic information system (GIS) technology to geotechnical instrumentation is highlighted in this paper. GIS technology is being used in the Central Artery/Tunnel (CA/T) Project, a multi-billion dollar, multi-discipline design and construction effort addressing traffic problems in downtown Boston, Massachusetts. The project will construct an eight-to-ten lane underground highway to replace the existing elevated Artery, and a cross-harbor tunnel connecting South Boston with Logan International Airport. The GIS development approach, application design process, and application modules are described. The GIS provides spatial analysis, geographic correlation, and cartographic display capabilities with rapid retrieval, thereby enhancing decision-making, management, and productivity throughout the construction and operations phases of the CA/T Project.

  18. Collagen tissue engineering: development of novel biomaterials and applications. (United States)

    Cen, Lian; Liu, Wei; Cui, Lei; Zhang, Wenjie; Cao, Yilin


    Scientific investigations involving collagen have inspired tissue engineering and design of biomaterials since collagen fibrils and their networks primarily regulate and define most tissues. The collagen networks form a highly organized, three-dimensional architecture to entrap other ingredients. Biomaterials are expected to function as cell scaffolds to replace native collagen-based extracellular matrix. The composition and properties of biomaterials used as scaffold for tissue engineering significantly affect the regeneration of neo-tissues and influence the conditions of collagen engineering. The complex scenario of collagen characteristics, types, fibril arrangement, and collagen structure-related functions (in a variety of connective tissues including bone, cartilage, tendon, skin and cornea) are addressed in this review. Discussion will focus on nanofibrillar assemblies and artificial synthetic peptides that mimic either the fibrillar structure or the elemental components of type I collagen as illustrated by their preliminary applications in tissue engineering. Conventional biomaterials used as scaffolds in engineering collagen-containing tissues are also discussed. The design of novel biomaterials and application of conventional biomaterials will facilitate development of additional novel tissue engineering bioproducts by refining the currently available techniques. The field of tissue engineering will ultimately be advanced by increasing control of collagen in native tissue and by continual manipulation of biomaterials.

  19. Technical progress report for application of numerical simulation methodology to automotive combustion

    Energy Technology Data Exchange (ETDEWEB)



    The third quarterly technical progress report is presented for DOE Contract No. DE-AC-03-79-ET15397.001 entitled, Application of Numerical Simulation Methodology to Automotive Combustion. Work during the period has concentrated on completing the model development and validation for in-cylinder fluid dynamics via: simulation (and data comparison) for piston induced vortex roll-up at high Reynolds number; simulation (and data comparison) for the decay of swirl in the Sandia DISC engine; and definition of compression cycle parametric cycle simulations. The results of these studies are described.

  20. A TT&C Performance Simulator for Space Exploration and Scientific Satellites - Architecture and Applications (United States)

    Donà, G.; Faletra, M.


    This paper presents the TT&C performance simulator toolkit developed internally at Thales Alenia Space Italia (TAS-I) to support the design of TT&C subsystems for space exploration and scientific satellites. The simulator has a modular architecture and has been designed using a model-based approach using standard engineering tools such as MATLAB/SIMULINK and mission analysis tools (e.g. STK). The simulator is easily reconfigurable to fit different types of satellites, different mission requirements and different scenarios parameters. This paper provides a brief description of the simulator architecture together with two examples of applications used to demonstrate some of the simulator’s capabilities.

  1. Mathematical model of marine diesel engine simulator for a new methodology of self propulsion tests

    Energy Technology Data Exchange (ETDEWEB)

    Izzuddin, Nur; Sunarsih,; Priyanto, Agoes [Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, 81310 Skudai, Johor (Malaysia)


    As a vessel operates in the open seas, a marine diesel engine simulator whose engine rotation is controlled to transmit through propeller shaft is a new methodology for the self propulsion tests to track the fuel saving in a real time. Considering the circumstance, this paper presents the real time of marine diesel engine simulator system to track the real performance of a ship through a computer-simulated model. A mathematical model of marine diesel engine and the propeller are used in the simulation to estimate fuel rate, engine rotating speed, thrust and torque of the propeller thus achieve the target vessel’s speed. The input and output are a real time control system of fuel saving rate and propeller rotating speed representing the marine diesel engine characteristics. The self-propulsion tests in calm waters were conducted using a vessel model to validate the marine diesel engine simulator. The simulator then was used to evaluate the fuel saving by employing a new mathematical model of turbochargers for the marine diesel engine simulator. The control system developed will be beneficial for users as to analyze different condition of vessel’s speed to obtain better characteristics and hence optimize the fuel saving rate.

  2. Mathematical model of marine diesel engine simulator for a new methodology of self propulsion tests (United States)

    Izzuddin, Nur; Sunarsih, Priyanto, Agoes


    As a vessel operates in the open seas, a marine diesel engine simulator whose engine rotation is controlled to transmit through propeller shaft is a new methodology for the self propulsion tests to track the fuel saving in a real time. Considering the circumstance, this paper presents the real time of marine diesel engine simulator system to track the real performance of a ship through a computer-simulated model. A mathematical model of marine diesel engine and the propeller are used in the simulation to estimate fuel rate, engine rotating speed, thrust and torque of the propeller thus achieve the target vessel's speed. The input and output are a real time control system of fuel saving rate and propeller rotating speed representing the marine diesel engine characteristics. The self-propulsion tests in calm waters were conducted using a vessel model to validate the marine diesel engine simulator. The simulator then was used to evaluate the fuel saving by employing a new mathematical model of turbochargers for the marine diesel engine simulator. The control system developed will be beneficial for users as to analyze different condition of vessel's speed to obtain better characteristics and hence optimize the fuel saving rate.

  3. Mathematical modeling and computational intelligence in engineering applications

    CERN Document Server

    Silva Neto, Antônio José da; Silva, Geraldo Nunes


    This book brings together a rich selection of studies in mathematical modeling and computational intelligence, with application in several fields of engineering, like automation, biomedical, chemical, civil, electrical, electronic, geophysical and mechanical engineering, on a multidisciplinary approach. Authors from five countries and 16 different research centers contribute with their expertise in both the fundamentals and real problems applications based upon their strong background on modeling and computational intelligence. The reader will find a wide variety of applications, mathematical and computational tools and original results, all presented with rigorous mathematical procedures. This work is intended for use in graduate courses of engineering, applied mathematics and applied computation where tools as mathematical and computational modeling, numerical methods and computational intelligence are applied to the solution of real problems.

  4. Engine panel seals for hypersonic engine applications: High temperature leakage assessments and flow modelling (United States)

    Steinetz, Bruce M.; Mutharasan, Rajakkannu; Du, Guang-Wu; Miller, Jeffrey H.; Ko, Frank


    A critical mechanical system in advanced hypersonic engines is the panel-edge seal system that seals gaps between the articulating horizontal engine panels and the adjacent engine splitter walls. Significant advancements in seal technology are required to meet the extreme demands placed on the seals, including the simultaneous requirements of low leakage, conformable, high temperature, high pressure, sliding operation. In this investigation, the seal concept design and development of two new seal classes that show promise of meeting these demands will be presented. These seals include the ceramic wafer seal and the braided ceramic rope seal. Presented are key elements of leakage flow models for each of these seal types. Flow models such as these help designers to predict performance-robbing parasitic losses past the seals, and estimate purge coolant flow rates. Comparisons are made between measured and predicted leakage rates over a wide range of engine simulated temperatures and pressures, showing good agreement.

  5. Studies on SI engine simulation and air/fuel ratio control systems design


    Bai, Yang


    This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University. More stringent Euro 6 and LEV III emission standards will immediately begin execution on 2014 and 2015 respectively. Accurate air/fuel ratio control can effectively reduce vehicle emission. The simulation of engine dynamic system is a very powerful method for developing and analysing engine and engine controller. Currently, most engine air/fuel ratio control used look-up table combined with p...

  6. Engaging Undergraduate Students in Transportation Studies through Simulating Transportation for Realistic Engineering Education and Training (STREET)


    Chen-Fu Liao; David Levinson; Henry Liu


    The practice of transportation engineering and planning has evolved substantially over the past several decades. A new paradigm for transportation engineering education is required to better engage students and deliver knowledge. Simulation tools have been used by transportation professionals to evaluate and analyze the potential impact of design or control strategy changes. Conveying complex transportation concepts can be effectively achieved by exploring them through simulation. Simulation ...


    Directory of Open Access Journals (Sweden)

    Dobre Daniel


    Full Text Available This article discusses the relation between the concept of symmetry and its applications in engineering. "Symmetry" is interpreted in a broad sense as repeated, coplanar shape fragments. An analysis of symmetry, which justifies its applications in engineering is given and discussed. After a brief explication of group theory and symmetry types, we show that there are industrial workpieces where symmetry is omnipresent. The analysis of symmetry can also be utilized for future research concerns the combining symmetry information with other functional characteristic of digital 3D design.

  8. Introduction to Plasma Technology Science, Engineering and Applications

    CERN Document Server

    Harry, John Ernest


    Written by a university lecturer with more than forty years experience in plasma technology, this book adopts a didactic approach in its coverage of the theory, engineering and applications of technological plasmas. The theory is developed in a unified way to enable brevity and clarity, providing readers with the necessary background to assess the factors that affect the behavior of plasmas under different operating conditions. The major part of the book is devoted to the applications of plasma technology and their accompanying engineering aspects, classified by the various pressure and densit

  9. Applications of CRISPR Genome Engineering in Cell Biology. (United States)

    Wang, Fangyuan; Qi, Lei S


    Recent advances in genome engineering are starting a revolution in biological research and translational applications. The clustered regularly interspaced short palindromic repeats (CRISPR)-associated RNA-guided endonuclease CRISPR associated protein 9 (Cas9) and its variants enable diverse manipulations of genome function. In this review, we describe the development of Cas9 tools for a variety of applications in cell biology research, including the study of functional genomics, the creation of transgenic animal models, and genomic imaging. Novel genome engineering methods offer a new avenue to understand the causality between the genome and phenotype, thus promising a fuller understanding of cell biology. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Pharmaceutical and biomedical applications of surface engineered carbon nanotubes. (United States)

    Mehra, Neelesh Kumar; Jain, Keerti; Jain, Narendra Kumar


    Surface engineered carbon nanotubes (CNTs) are attracting recent attention of scientists owing to their vivid biomedical and pharmaceutical applications. The focus of this review is to highlight the important role of surface engineered CNTs in the highly challenging but rewarding area of nanotechnology. The major strength of this review lies in highlighting the exciting applications of CNTs to boost the research efforts, which unfortunately are otherwise scattered in the literature making the reading non-coherent and non-homogeneous. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Implementation of Scientific Computing Applications on the Cell Broadband Engine

    Directory of Open Access Journals (Sweden)

    Guochun Shi


    Full Text Available The Cell Broadband Engine architecture is a revolutionary processor architecture well suited for many scientific codes. This paper reports on an effort to implement several traditional high-performance scientific computing applications on the Cell Broadband Engine processor, including molecular dynamics, quantum chromodynamics and quantum chemistry codes. The paper discusses data and code restructuring strategies necessary to adapt the applications to the intrinsic properties of the Cell processor and demonstrates performance improvements achieved on the Cell architecture. It concludes with the lessons learned and provides practical recommendations on optimization techniques that are believed to be most appropriate.

  12. Requirements Engineering of Context-Aware Applications


    Alalshuhai, Ahmed


    Context-aware computing envisions a new generation of smart applications that have the ability to perpetually sense the user’s context and use these data to make adaptation decision in response to changes in the user’s context so as to provide timely and personalized services anytime and anywhere. Unlike the traditional distribution systems where the network topology is fixed and wired, context-aware computing systems are mostly based on wireless communication due to the mobility of the netwo...

  13. Qualitative knowledge engineering for nuclear applications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jae H.; Kim, Ko R.; Lee, Jae C.


    After the TMI nuclear power plant accident, the two topics of plant safety and operational efficiency became more important areas of artificial intelligence, which have difference characteristics. Qualitative deep model is the recently prospective technology of AI, that can overcome several handicaps of the existing expert systems such as lack of common sense reasoning. The application of AI to the large and complex system like nuclear power plants is typically and effectively done through a module-based hierarchical system. As each module has to be built with suitable AI system. Through the experiences of hierarchical system construction, we aimed to develop basic AI application schemes for the power plant safety and operational efficiency as well as basic technologies for autonomous power plants. The goal of the research is to develop qualitative reasoning technologies for nuclear power plants. For this purpose, the development of qualitative modeling technologies and qualitative behaviour prediction technologies of the power plant are accomplished. In addition, the feasibility of application of typical qualitative reasoning technologies to power plants is studied . The goal of the application is to develop intelligent control technologies of power plants, support technologies. For these purposes, we analyzed the operation of power plants according to its operation purpose: power generation operation, shut-down and start-up operation. As a result, qualitative model of basic components were sketched, including pipes, valves, pumps and heat exchangers. Finally, plant behaviour prediction technologies through qualitative plant heat transfer model and design support technologies through 2nd-order differential equation were developed. For the construction of AI system of power plants, we have studied on the mixed module based hierarchical software. As a testbed, we have considered the spent fuel system and the feedwater system. We also studied the integration

  14. Geometry and Simulation Results for a Gas Turbine Representative of the Energy Efficient Engine (EEE) (United States)

    Claus, Russell W.; Beach, Tim; Turner, Mark; Hendricks, Eric S.


    This paper describes the geometry and simulation results of a gas-turbine engine based on the original EEE engine developed in the 1980s. While the EEE engine was never in production, the technology developed during the program underpins many of the current generation of gas turbine engines. This geometry is being explored as a potential multi-stage turbomachinery test case that may be used to develop technology for virtual full-engine simulation. Simulation results were used to test the validity of each component geometry representation. Results are compared to a zero-dimensional engine model developed from experimental data. The geometry is captured in a series of Initial Graphical Exchange Specification (IGES) files and is available on a supplemental DVD to this report.

  15. 46 CFR 113.35-15 - Mechanical engine order telegraph systems; application. (United States)


    ... 46 Shipping 4 2010-10-01 2010-10-01 false Mechanical engine order telegraph systems; application...) ELECTRICAL ENGINEERING COMMUNICATION AND ALARM SYSTEMS AND EQUIPMENT Engine Order Telegraph Systems § 113.35-15 Mechanical engine order telegraph systems; application. If a mechanical engine order telegraph...

  16. Thermodynamics. Application to chemical engineering and petroleum industry; Thermodynamique. Application au genie chimique et a l`industrie petroliere

    Energy Technology Data Exchange (ETDEWEB)

    Vidal, J. [Institut Francais du Petrole (IFP), 92 - Rueil-Malmaison (France)]|[Ecole Nationale Superieure du Petrole et des Moteurs (ENSPM), 92 - Rueil-Malmaison (France)


    The processes simulation and their optimization assume that the thermodynamic properties and the phase equilibria of the studied mixings are well known. This knowledge is not only based on the experimental measures but also on calculation methods involving the thermodynamics principles. The aim of this book is to describe these methods, their development and their applications in the fields of chemical engineering and petroleum industry. The basic concepts are at first described. Then the author insists on the models which have a predictive character. Some numerical examples specify the application of these notions and of these models. A very important bibliography allows to complete the already acquired knowledge. (O.M.) 473 refs.

  17. Using elements of game engine architecture to simulate sensor networks for eldercare. (United States)

    Godsey, Chad; Skubic, Marjorie


    When dealing with a real time sensor network, building test data with a known ground truth is a tedious and cumbersome task. In order to quickly build test data for such a network, a simulation solution is a viable option. Simulation environments have a close relationship with computer game environments, and therefore there is much to be learned from game engine design. In this paper, we present our vision for a simulated in-home sensor network and describe ongoing work on using elements of game engines for building the simulator. Validation results are included to show agreement on motion sensor simulation with the physical environment.

  18. Solar energy sciences and engineering applications

    CERN Document Server

    Enteria, Napoleon


    Solar energy is available all over the world in different intensities. Theoretically, the solar energy available on the surface of the earth is enough to support the energy requirements of the entire planet. However, in reality, progress and development of solar science and technology depends to a large extent on human desires and needs. This is due to the various barriers to overcome and to deal with the economics of practical utilization of solar energy.This book will introduce the rapid development and progress in the field of solar energy applications for science and technology: the advanc

  19. Developments of three-dimensional computer-aided engineering simulation for injection moulding (United States)

    Kim, Sang-Woo; Turng, Lih-Sheng


    This paper presents the state-of-the-art technology and developments of three-dimensional computer-aided engineering (CAE) simulation for injection moulding. It is aimed at providing insights into the emerging three-dimensional CAE tools to facilitate judicious application and further developments of these tools for design and manufacturing of complex injection moulded parts. It begins with background information on the evolution of CAE for injection moulding, followed by a discussion of advantages and limitations inherent with the widely adopted 2.5-dimensional Hele-Shaw flow approximation. After that, the mathematical formulations and numerical methods used in three-dimensional simulation are presented. This paper also discusses some special issues related to three-dimensional simulation, such as intensive CPU requirement and solution resolution in the gap-wise direction. A number of illustrative examples are presented to demonstrate the capabilities of three-dimensional simulation and the difference between predictions from the 2.5-dimensional and three-dimensional analyses.

  20. Suppression of pool fires with HRC-125 in a simulated engine nacelle.

    Energy Technology Data Exchange (ETDEWEB)

    Keyser, David R. (INS, Inc., Lexington Park, MD); Hewson, John C.


    CFD simulations are conducted to predict the distribution of fire suppressant in an engine nacelle and to predict the suppression of pool fires by the application of this suppressant. In the baseline configuration, which is based on an installed system, suppressant is injected through four nozzles at a rate fast enough to suppress all simulated pool fires. Variations that reduce the mass of the suppression system (reducing the impact of the suppression system on meeting mission needs) are considered, including a reduction in the rate of suppressant injection, a reduction in the mass of suppressant and a reduction in the number of nozzles. In general, these variations should work to reduce the effectiveness of the suppression system, but the CFD results point out certain changes that have negligible impact, at least for the range of phenomena considered here. The results are compared with measurements where available. Comparisons with suppressant measurements are reasonable. A series of twenty-three fire suppression tests were conducted to check the predictions. The pre-test predictions were generally successful in identifying the range of successful suppression tests. In two separate cases, each where one nozzle of the suppression system was capped, the simulation results did indicate a failure to suppress for a condition where the tests indicated successful suppression. When the test-suppressant discharge rate was reduced by roughly 25%, the tests were in agreement with the predictions. That is, the simulations predict a failure to suppress slightly before observed in these cases.

  1. High-fidelity simulations of unsteady civil aircraft aerodynamics: stakes and perspectives. Application of zonal detached eddy simulation. (United States)

    Deck, Sébastien; Gand, Fabien; Brunet, Vincent; Ben Khelil, Saloua


    This paper provides an up-to-date survey of the use of zonal detached eddy simulations (ZDES) for unsteady civil aircraft applications as a reflection on the stakes and perspectives of the use of hybrid methods in the framework of industrial aerodynamics. The issue of zonal or non-zonal treatment of turbulent flows for engineering applications is discussed. The ZDES method used in this article and based on a fluid problem-dependent zonalization is briefly presented. Some recent landmark achievements for conditions all over the flight envelope are presented, including low-speed (aeroacoustics of high-lift devices and landing gear), cruising (engine-airframe interactions), propulsive jets and off-design (transonic buffet and dive manoeuvres) applications. The implications of such results and remaining challenges in a more global framework are further discussed. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  2. Bioreactors in tissue engineering - principles, applications and commercial constraints. (United States)

    Hansmann, Jan; Groeber, Florian; Kahlig, Alexander; Kleinhans, Claudia; Walles, Heike


    Bioreactor technology is vital for tissue engineering. Usually, bioreactors are used to provide a tissue-specific physiological in vitro environment during tissue maturation. In addition to this most obvious application, bioreactors have the potential to improve the efficiency of the overall tissue-engineering concept. To date, a variety of bioreactor systems for tissue-specific applications have been developed. Of these, some systems are already commercially available. With bioreactor technology, various functional tissues of different types were generated and cultured in vitro. Nevertheless, these efforts and achievements alone have not yet led to many clinically successful tissue-engineered implants. We review possible applications for bioreactor systems within a tissue-engineering process and present basic principles and requirements for bioreactor development. Moreover, the use of bioreactor systems for the expansion of clinically relevant cell types is addressed. In contrast to cell expansion, for the generation of functional three-dimensional tissue equivalents, additional physical cues must be provided. Therefore, bioreactors for musculoskeletal tissue engineering are discussed. Finally, bioreactor technology is reviewed in the context of commercial constraints. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Process/Engineering Co-Simulation of Oxy-Combustion and Chemical Looping Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Sloan, David [Alstom Power Inc., Windsor, CT (United States)


    Over the past several years, the DOE has sponsored various funded programs, collectively referred to as Advanced Process Engineering Co-Simulator (APECS) programs, which have targeted the development of a steady-state simulator for advanced power plants. The simulator allows the DOE and its contractors to systematically evaluate various power plant concepts, either for preliminary conceptual design or detailed final design.

  4. Computational electromagnetics recent advances and engineering applications

    CERN Document Server


    Emerging Topics in Computational Electromagnetics in Computational Electromagnetics presents advances in Computational Electromagnetics. This book is designed to fill the existing gap in current CEM literature that only cover the conventional numerical techniques for solving traditional EM problems. The book examines new algorithms, and applications of these algorithms for solving problems of current interest that are not readily amenable to efficient treatment by using the existing techniques. The authors discuss solution techniques for problems arising in nanotechnology, bioEM, metamaterials, as well as multiscale problems. They present techniques that utilize recent advances in computer technology, such as parallel architectures, and the increasing need to solve large and complex problems in a time efficient manner by using highly scalable algorithms.

  5. Multifunctional silk-heparin biomaterials for vascular tissue engineering applications


    Seib, F. Philipp; Herklotz, Manuela; Burke, Kelly A; Maitz, Manfred F.; Werner, Carsten; Kaplan, David L.


    Over the past 30 years, silk has been proposed for numerous biomedical applications that go beyond its traditional use as a suture material. Silk sutures are well tolerated in humans, but the use of silk for vascular engineering applications still requires extensive biocompatibility testing. Some studies have indicated a need to modify silk to yield a hemocompatible surface. This study examined the potential of low molecular weight heparin as a material for refining silk properties by acting ...

  6. Handbook of power systems engineering with power electronics applications

    CERN Document Server

    Hase, Yoshihide


    Formerly known as Handbook of Power System Engineering, this second edition provides rigorous revisions to the original treatment of systems analysis together with a substantial new four-chapter section on power electronics applications. Encompassing a whole range of equipment, phenomena, and analytical approaches, this handbook offers a complete overview of power systems and their power electronics applications, and presents a thorough examination of the fundamental principles, combining theories and technologies that are usually treated in separate specialised fields, in a single u

  7. Advance elements of optoisolation circuits nonlinearity applications in engineering

    CERN Document Server

    Aluf, Ofer


    This book on advanced optoisolation circuits for nonlinearity applications in engineering addresses two separate engineering and scientific areas, and presents advanced analysis methods for optoisolation circuits that cover a broad range of engineering applications. The book analyzes optoisolation circuits as linear and nonlinear dynamical systems and their limit cycles, bifurcation, and limit cycle stability by using Floquet theory. Further, it discusses a broad range of bifurcations related to optoisolation systems: cusp-catastrophe, Bautin bifurcation, Andronov-Hopf bifurcation, Bogdanov-Takens (BT) bifurcation, fold Hopf bifurcation, Hopf-Hopf bifurcation, Torus bifurcation (Neimark-Sacker bifurcation), and Saddle-loop or Homoclinic bifurcation. Floquet theory helps as to analyze advance optoisolation systems. Floquet theory is the study of the stability of linear periodic systems in continuous time. Another way to describe Floquet theory, it is the study of linear systems of differential equations with p...

  8. 4th International Conference in Software Engineering for Defence Applications

    CERN Document Server

    Sillitti, Alberto; Succi, Giancarlo; Messina, Angelo


    This book presents high-quality original contributions on new software engineering models, approaches, methods, and tools and their evaluation in the context of defence and security applications. In addition, important business and economic aspects are discussed, with a particular focus on cost/benefit analysis, new business models, organizational evolution, and business intelligence systems. The contents are based on presentations delivered at SEDA 2015, the 4th International Conference in Software Engineering for Defence Applications, which was held in Rome, Italy, in May 2015. This conference series represents a targeted response to the growing need for research that reports and debates the practical implications of software engineering within the defence environment and also for software performance evaluation in real settings through controlled experiments as well as case and field studies. The book will appeal to all with an interest in modeling, managing, and implementing defence-related software devel...

  9. Biomaterial based cardiac tissue engineering and its applications. (United States)

    Huyer, Locke Davenport; Montgomery, Miles; Zhao, Yimu; Xiao, Yun; Conant, Genevieve; Korolj, Anastasia; Radisic, Milica


    Cardiovascular disease is a leading cause of death worldwide, necessitating the development of effective treatment strategies. A myocardial infarction involves the blockage of a coronary artery leading to depletion of nutrient and oxygen supply to cardiomyocytes and massive cell death in a region of the myocardium. Cardiac tissue engineering is the growth of functional cardiac tissue in vitro on biomaterial scaffolds for regenerative medicine application. This strategy relies on the optimization of the complex relationship between cell networks and biomaterial properties. In this review, we discuss important biomaterial properties for cardiac tissue engineering applications, such as elasticity, degradation, and induced host response, and their relationship to engineered cardiac cell environments. With these properties in mind, we also emphasize in vitro use of cardiac tissues for high-throughput drug screening and disease modelling.

  10. Engineering mechanical microenvironment of macrophage and its biomedical applications. (United States)

    Li, Jing; Li, Yuhui; Gao, Bin; Qin, Chuanguang; He, Yining; Xu, Feng; Yang, Hui; Lin, Min


    Macrophages are the most plastic cells in the hematopoietic system and can be widely found in almost all tissues. Recently studies have shown that mechanical cues (e.g., matrix stiffness and stress/strain) can significantly affect macrophage behaviors. Although existing reviews on the physical and mechanical cues that regulate the macrophage's phenotype are available, engineering mechanical microenvironment of macrophages in vitro as well as a comprehensive overview and prospects for their biomedical applications (e.g., tissue engineering and immunotherapy) has yet to be summarized. Thus, this review provides an overview on the existing methods for engineering mechanical microenvironment of macrophages in vitro and then a section on their biomedical applications and further perspectives are presented.



  12. Sterilization techniques for biodegradable scaffolds in tissue engineering applications


    Dai, Zheng; Ronholm, Jennifer; Tian, Yiping; Sethi, Benu; Cao, Xudong


    Biodegradable scaffolds have been extensively studied due to their wide applications in biomaterials and tissue engineering. However, infections associated with in vivo use of these scaffolds by different microbiological contaminants remain to be a significant challenge. This review focuses on different sterilization techniques including heat, chemical, irradiation, and other novel sterilization techniques for various ...

  13. Towards Model-Driven Engineering Constraint-Based Scheduling Applications


    de Siqueira Teles, Fabrício


    de Siqueira Teles, Fabrício; Pierre Louis Robin, Jacques. Towards Model-Driven Engineering Constraint-Based Scheduling Applications. 2008. Dissertação (Mestrado). Programa de Pós-Graduação em Ciência da Computação, Universidade Federal de Pernambuco, Recife, 2008.

  14. Application of an acoustofluidic perfusion bioreactor for cartilage tissue engineering


    Li, Siwei; Glynne-Jones, Peter; Andriotis, Orestis G.; Ching, Kuan Y.; Jonnalagadda, Umesh S.; Oreffo, Richard O.C.; Hill, Martyn; Tare, Rahul S.


    Cartilage grafts generated using conventional static tissue engineering strategies are characterised by low cell viability, suboptimal hyaline cartilage formation and, critically, inferior mechanical competency, which limit their application for resurfacing articular cartilage defects. To address the limitations of conventional static cartilage bioengineering strategies and generate robust, scaffold-free neocartilage grafts of human articular chondrocytes, the present study utilised custom-bu...

  15. Refresher Course on Tensors and their Applications in Engineering ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 11; Issue 7. Refresher Course on Tensors and their Applications in Engineering Sciences. Information and Announcements Volume 11 Issue 7 July 2006 pp 100-100. Fulltext. Click here to view fulltext PDF. Permanent link:

  16. Use and Application of Quality Engineering in Increasing ...

    African Journals Online (AJOL)

    The purpose of this paper is to demonstrate uses and application of quality engineering in general and Taguchi methods in particular in Ethiopian Plastic Share Company (EPSC) main processes. As a methodology, secondary data from the company has been collected and used to identify process variation and their ...

  17. Application of Plagiarism Screening Software in the Chemical Engineering Curriculum (United States)

    Cooper, Matthew E.; Bullard, Lisa G.


    Plagiarism is an area of increasing concern for written ChE assignments, such as laboratory and design reports, due to ease of access to text and other materials via the internet. This study examines the application of plagiarism screening software to four courses in a university chemical engineering curriculum. The effectiveness of plagiarism…

  18. Development of Desktop Computing Applications and Engineering Tools on GPUs

    DEFF Research Database (Denmark)

    Sørensen, Hans Henrik Brandenborg; Glimberg, Stefan Lemvig; Hansen, Toke Jansen

    (GPUs) for high-performance computing applications and software tools in science and engineering, inverse problems, visualization, imaging, dynamic optimization. The goals are to contribute to the development of new state-of-the-art mathematical models and algorithms for maximum throughout performance...

  19. Model-Based Control of a Nonlinear Aircraft Engine Simulation using an Optimal Tuner Kalman Filter Approach (United States)

    Connolly, Joseph W.; Csank, Jeffrey Thomas; Chicatelli, Amy; Kilver, Jacob


    This paper covers the development of a model-based engine control (MBEC) methodology featuring a self tuning on-board model applied to an aircraft turbofan engine simulation. Here, the Commercial Modular Aero-Propulsion System Simulation 40,000 (CMAPSS40k) serves as the MBEC application engine. CMAPSS40k is capable of modeling realistic engine performance, allowing for a verification of the MBEC over a wide range of operating points. The on-board model is a piece-wise linear model derived from CMAPSS40k and updated using an optimal tuner Kalman Filter (OTKF) estimation routine, which enables the on-board model to self-tune to account for engine performance variations. The focus here is on developing a methodology for MBEC with direct control of estimated parameters of interest such as thrust and stall margins. Investigations using the MBEC to provide a stall margin limit for the controller protection logic are presented that could provide benefits over a simple acceleration schedule that is currently used in traditional engine control architectures.

  20. The impact of improved sparse linear solvers on industrial engineering applications

    Energy Technology Data Exchange (ETDEWEB)

    Heroux, M. [Cray Research, Inc., Eagan, MN (United States); Baddourah, M.; Poole, E.L.; Yang, Chao Wu


    There are usually many factors that ultimately determine the quality of computer simulation for engineering applications. Some of the most important are the quality of the analytical model and approximation scheme, the accuracy of the input data and the capability of the computing resources. However, in many engineering applications the characteristics of the sparse linear solver are the key factors in determining how complex a problem a given application code can solve. Therefore, the advent of a dramatically improved solver often brings with it dramatic improvements in our ability to do accurate and cost effective computer simulations. In this presentation we discuss the current status of sparse iterative and direct solvers in several key industrial CFD and structures codes, and show the impact that recent advances in linear solvers have made on both our ability to perform challenging simulations and the cost of those simulations. We also present some of the current challenges we have and the constraints we face in trying to improve these solvers. Finally, we discuss future requirements for sparse linear solvers on high performance architectures and try to indicate the opportunities that exist if we can develop even more improvements in linear solver capabilities.

  1. Experiences with Integrating Simulation into a Software Engineering Curriculum (United States)

    Bollin, Andreas; Hochmuller, Elke; Mittermeir, Roland; Samuelis, Ladislav


    Software Engineering education must account for a broad spectrum of knowledge and skills software engineers will be required to apply throughout their professional life. Covering all the topics in depth within a university setting is infeasible due to curricular constraints as well as due to the inherent differences between educational…

  2. Sandia technology: Engineering and science applications (United States)

    Maydew, M. C.; Parrot, H.; Dale, B. C.; Floyd, H. L.; Leonard, J. A.; Parrot, L.


    This report discusses: protecting environment, safety, and health; Sandia's quality initiative; Sandia vigorously pursues technology transfer; scientific and technical education support programs; nuclear weapons development; recognizing battlefield targets with trained artificial neural networks; battlefield robotics: warfare at a distance; a spinning shell sizes up the enemy; thwarting would-be nuclear terrorists; unattended video surveillance system for nuclear facilities; making the skies safer for travelers; onboard instrumentation system to evaluate performance of stockpile bombs; keeping track with lasers; extended-life lithium batteries; a remote digital video link acquires images securely; guiding high-performance missiles with laser gyroscopes; nonvolatile memory chips for space applications; initiating weapon explosives with lasers; next-generation optoelectronics and microelectronics technology developments; chemometrics: new methods for improving chemical analysis; research team focuses ion beam to record-breaking intensities; standardizing the volt to quantum accuracy; new techniques improve robotic software development productivity; a practical laser plasma source for generating soft x-rays; exploring metal grain boundaries; massively parallel computing; modeling the amount of desiccant needed for moisture control; attacking pollution with sunshine; designing fuel-conversion catalysts with computers; extending a nuclear power plant's useful life; plasma-facing components for the International Thermonuclear Experimental Reactor.

  3. Closed loop models for analyzing engineering requirements for simulators (United States)

    Baron, S.; Muralidharan, R.; Kleinman, D.


    A closed loop analytic model, incorporating a model for the human pilot, (namely, the optimal control model) that would allow certain simulation design tradeoffs to be evaluated quantitatively was developed. This model was applied to a realistic flight control problem. The resulting model is used to analyze both overall simulation effects and the effects of individual elements. The results show that, as compared to an ideal continuous simulation, the discrete simulation can result in significant performance and/or workload penalties.

  4. Computational wind engineering and its application in civil engineering. Aerodynamic and aeroelastic analysis


    Awruch, A.M.; Braun, A.L.; Greco, M.


    Experimental tests in wind tunnels have been traditionally employed as a fundamental tool to evaluate aerodynamic and aeroelastic effects due to wind action on civil engineering structures, such as bridges and slender buildings. In the last decades, due to the versatility presented by numerical methods to change physical as well as geometrical parameters, numerical simulation has become a very attractive tool. Computational Fluid Dynamics (CFD), Computational Structural Dynamics (CSD) togethe...

  5. Applications of synchrotron radiation to Chemical Engineering Science: Workshop report

    Energy Technology Data Exchange (ETDEWEB)


    This report contains extended abstracts that summarize presentations made at the Workshop on Applications of Synchrotron Radiation to Chemical Engineering Science held at Argonne National Laboratory (ANL), Argonne, IL, on April 22--23, 1991. The talks emphasized the application of techniques involving absorption fluorescence, diffraction, and reflection of synchrotron x-rays, with a focus on problems in applied chemistry and chemical engineering, as well as on the use of x-rays in topographic, tomographic, and lithographic procedures. The attendees at the workshop included experts in the field of synchrotron science, scientists and engineers from ANL, other national laboratories, industry, and universities; and graduate and undergraduate students who were enrolled in ANL educational programs at the time of the workshop. Talks in the Plenary and Overview Session described the status of and special capabilities to be offered by the Advanced Photon Source (APS), as well as strategies and opportunities for utilization of synchrotron radiation to solve science and engineering problems. Invited talks given in subsequent sessions covered the use of intense infrared, ultraviolet, and x-ray photon beams (as provided by synchrotrons) in traditional and nontraditional areas of chemical engineering research related to electrochemical and corrosion science, catalyst development and characterization, lithography and imaging techniques, and microanalysis.

  6. Transcription control engineering and applications in synthetic biology

    Directory of Open Access Journals (Sweden)

    Michael D. Engstrom


    Full Text Available In synthetic biology, researchers assemble biological components in new ways to produce systems with practical applications. One of these practical applications is control of the flow of genetic information (from nucleic acid to protein, a.k.a. gene regulation. Regulation is critical for optimizing protein (and therefore activity levels and the subsequent levels of metabolites and other cellular properties. The central dogma of molecular biology posits that information flow commences with transcription, and accordingly, regulatory tools targeting transcription have received the most attention in synthetic biology. In this mini-review, we highlight many past successes and summarize the lessons learned in developing tools for controlling transcription. In particular, we focus on engineering studies where promoters and transcription terminators (cis-factors were directly engineered and/or isolated from DNA libraries. We also review several well-characterized transcription regulators (trans-factors, giving examples of how cis- and trans-acting factors have been combined to create digital and analogue switches for regulating transcription in response to various signals. Last, we provide examples of how engineered transcription control systems have been used in metabolic engineering and more complicated genetic circuits. While most of our mini-review focuses on the well-characterized bacterium Escherichia coli, we also provide several examples of the use of transcription control engineering in non-model organisms. Similar approaches have been applied outside the bacterial kingdom indicating that the lessons learned from bacterial studies may be generalized for other organisms.

  7. Foil Bearing Starting Considerations and Requirements for Rotorcraft Engine Applications (United States)

    Radil, Kevin C.; DellaCorte, Christopher


    Foil gas bearings under development for rotorcraft-sized, hot core engine applications have been susceptible to damage from the slow acceleration and rates typically encountered during the pre-ignition stage in conventional engines. Recent laboratory failures have been assumed to be directly linked to operating foil bearings below their lift-off speed while following conventional startup procedures for the engines. In each instance, the continuous sliding contact between the foils and shaft was believed to thermally overload the bearing and cause the engines to fail. These failures highlight the need to characterize required acceleration rates and minimum operating speeds for these applications. In this report, startup experiments were conducted with a large, rotorcraft engine sized foil bearing under moderate load and acceleration rates to identify the proper start procedures needed to avoid bearing failure. The results showed that a bearing under a 39.4 kPa static load can withstand a modest acceleration rate of 500 rpm/s and excessive loitering below the bearing lift-off speed provided an adequate solid lubricant is present.

  8. Recent Advances in Application of Biosensors in Tissue Engineering (United States)

    Paul, Arghya; Lee, Yong-kyu; Jaffa, Ayad A.


    Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose, and H2O2 as well as serum proteins of large molecular size, such as albumin and alpha-fetoprotein, and inflammatory cytokines, such as IFN-g and TNF-α. In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications. PMID:25165697

  9. Recent Advances in Application of Biosensors in Tissue Engineering

    Directory of Open Access Journals (Sweden)

    Anwarul Hasan


    Full Text Available Biosensors research is a fast growing field in which tens of thousands of papers have been published over the years, and the industry is now worth billions of dollars. The biosensor products have found their applications in numerous industries including food and beverages, agricultural, environmental, medical diagnostics, and pharmaceutical industries and many more. Even though numerous biosensors have been developed for detection of proteins, peptides, enzymes, and numerous other biomolecules for diverse applications, their applications in tissue engineering have remained limited. In recent years, there has been a growing interest in application of novel biosensors in cell culture and tissue engineering, for example, real-time detection of small molecules such as glucose, lactose, and H2O2 as well as serum proteins of large molecular size, such as albumin and alpha-fetoprotein, and inflammatory cytokines, such as IFN-g and TNF-α. In this review, we provide an overview of the recent advancements in biosensors for tissue engineering applications.

  10. Phase locked loops design, simulation, and applications

    CERN Document Server

    Best, Roland E


    The Definitive Introduction to Phase-Locked Loops, Complete with Software for Designing Wireless Circuits! The Sixth Edition of Roland Best's classic Phase-Locked Loops has been updated to equip you with today's definitive introduction to PLL design, complete with powerful PLL design and simulation software written by the author. Filled with all the latest PLL advances, this celebrated sourcebook now includes new chapters on frequency synthesis…CAD for PLLs…mixed-signal PLLs…all-digital PLLs…and software PLLs_plus a new collection of sample communications applications. An essential tool for achieving cutting-edge PLL design, the Sixth Edition of Phase-Locked Loops features: A wealth of easy-to-use methods for designing phase-locked loops Over 200 detailed illustrations New to this edition: new chapters on frequency synthesis, including fractional-N PLL frequency synthesizers using sigma-delta modulators; CAD for PLLs, mixed-signal PLLs, all-digital PLLs, and software PLLs; new PLL communications ap...

  11. 3D-Printed Biopolymers for Tissue Engineering Application

    Directory of Open Access Journals (Sweden)

    Xiaoming Li


    Full Text Available 3D printing technology has recently gained substantial interest for potential applications in tissue engineering due to the ability of making a three-dimensional object of virtually any shape from a digital model. 3D-printed biopolymers, which combine the 3D printing technology and biopolymers, have shown great potential in tissue engineering applications and are receiving significant attention, which has resulted in the development of numerous research programs regarding the material systems which are available for 3D printing. This review focuses on recent advances in the development of biopolymer materials, including natural biopolymer-based materials and synthetic biopolymer-based materials prepared using 3D printing technology, and some future challenges and applications of this technology are discussed.

  12. Application of Maximum Entropy Method to Semiconductor Engineering

    Directory of Open Access Journals (Sweden)

    Yoshiki Yonamoto


    Full Text Available The maximum entropy method (MEM is widely used in research fields such as linguistics, meteorology, physics, and chemistry. Recently, MEM application has become a subject of interest in the semiconductor engineering field, in which devices utilize very thin films composed of many materials. For thin film fabrication, it is essential to thoroughly understand atomic-scale structures, internal fixed charges, and bulk/interface traps, and many experimental techniques have been developed for evaluating these. However, the difficulty in interpreting the data they provide prevents the improvement of device fabrication processes. As a candidate for a very practical data analyzing technique, MEM is a promising approach to solve this problem. In this paper, we review the application of MEM to thin films used in semiconductor engineering. The method provides interesting and important information that cannot be obtained with conventional methods. This paper explains its theoretical background, important points for practical use, and application results.

  13. Simulation of a two-stroke diesel engine for propulsion in waves

    Directory of Open Access Journals (Sweden)

    Kevin Koosup Yum


    Full Text Available Propulsion in waves is a complex physical process that involves interactions between a hull, a propeller, a shaft and a prime mover which is often a diesel engine. Among the relevant components, the diesel engine plays an important role in the overall system dynamics. Therefore, using a proper model for the diesel engine is essential to achieve the reasonable accuracy of the transient simulation of the entire system. In this paper, a simulation model of a propulsion system in waves is presented with emphasis on modeling a two-stroke marine diesel engine: the framework for building such a model and its mathematical descriptions. The models are validated against available measurement data, and a sensitivity analysis for the transient performance of the diesel engine is carried out. Finally, the results of the system simulations under various wave conditions are analyzed to understand the physical processes and compare the efficiency for different cases.

  14. Probability with applications to investments, insurance, and engineering

    CERN Document Server

    Bean, Michael A


    This book covers the basic probability of distributions with an emphasis on applications from the areas of investments, insurance, and engineering. Written by a Fellow of the Casualty Actuarial Society and the Society of Actuaries with many years of experience as a university professor and industry practitioner, the book is suitable as a text for senior undergraduate and beginning graduate students in mathematics, statistics, actuarial science, finance, or engineering as well as a reference for practitioners in these fields. The book is particularly well suited for students preparing for profe

  15. Skin tissue engineering--in vivo and in vitro applications. (United States)

    Groeber, Florian; Holeiter, Monika; Hampel, Martina; Hinderer, Svenja; Schenke-Layland, Katja


    Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for the replacement of lost skin or for the establishment of human-based in vitro skin models. This review summarizes these advances in in vivo and in vitro applications of tissue-engineered skin. We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening. Copyright © 2011 Elsevier B.V. All rights reserved.

  16. Introduction to the application of genetic algorithms in engineering

    Directory of Open Access Journals (Sweden)

    I. S. Shaw


    Full Text Available Genetic algorithms constitute a new research area in the field of artificial intelligence. This work is aimed at their application in specific areas of engineering where good results have already been achieved. The purpose of this work is to provide a basic introduction for students as well as experienced engineers who wish to upgrade their knowledge. A distinctive feature of artificial intelligence is that instead of mathematical models, either direct human experience or certain functions of the human brain for the modelling of physical phenomena are used.

  17. Computer, Network, Software, and Hardware Engineering with Applications

    CERN Document Server

    Schneidewind, Norman F


    There are many books on computers, networks, and software engineering but none that integrate the three with applications. Integration is important because, increasingly, software dominates the performance, reliability, maintainability, and availability of complex computer and systems. Books on software engineering typically portray software as if it exists in a vacuum with no relationship to the wider system. This is wrong because a system is more than software. It is comprised of people, organizations, processes, hardware, and software. All of these components must be considered in an integr

  18. Engineering applications of discrete-time optimal control

    DEFF Research Database (Denmark)

    Vidal, Rene Victor Valqui; Ravn, Hans V.


    Many problems of design and operation of engineering systems can be formulated as optimal control problems where time has been discretisized. This is also true even if 'time' is not involved in the formulation of the problem, but rather another one-dimensional parameter. This paper gives a review...... of some well-known and new results in discrete time optimal control methods applicable to practical problem solving within engineering. Emphasis is placed on dynamic programming, the classical maximum principle and generalized versions of the maximum principle for optimal control of discrete time systems...

  19. Nanostructured materials for applications in drug delivery and tissue engineering. (United States)

    Goldberg, Michael; Langer, Robert; Jia, Xinqiao


    point of view, both the drug-delivery vehicles and tissue-engineering scaffolds need to be biocompatible and biodegradable. The biological functions of encapsulated drugs and cells can be dramatically enhanced by designing biomaterials with controlled organizations at the nanometer scale. This review summarizes the most recent development in utilizing nanostructured materials for applications in drug delivery and tissue engineering.

  20. Simulation of fuel demand for wood-gas in combustion engine

    Directory of Open Access Journals (Sweden)

    Botwinska Katarzyna


    Full Text Available In the era of the oil crisis and proceeding contamination of the natural environment, it is attempted to substitute fossil raw materials with alternative carriers. For many years, road transport has been considered as one of the main sources of the substances deteriorating air quality. Applicable European directives oblige the member states to implement biofuels and biocomponents into the general fuel market, however, such process is proceeding gradually and relatively slowly. So far, alternative fuels have been used on a large scale to substitute diesel fuel or petrol. Derivatives of vegetable raw materials, such as vegetable oils or their esters and ethanol extracted from biomass, are used to that end. It has been noticed that there is no alternative to LPG which, due to financial reasons, is more and more popular as fuel in passenger cars. In relation to solutions adopted in the past, it has been decided to analyse the option of powering a modern passenger car with wood gas - syngas. Such fuel has been practically used since the 1920's. To that end, a computer simulation created in SciLab environment was carried out. Passenger car Fiat Seicento, fitted with Fire 1.1 8V petrol engine with power of 40kW, whose parameters were used to prepare the model, was selected as the model vehicle. The simulation allows the determination of engine demand on the given fuel. Apart from the wood gas included in the title, petrol, methane and LPG were used. Additionally, the created model enables the determination of the engine power at the time of the indicated fuels supply. The results obtained in the simulation revealed considerable decrease in the engine power when the wood gas was supplied and the increased consumption of this fuel. On the basis of the analysis of the professional literature describing numerous inconveniences connected with the use of this fuel as well as the obtained results, it has been established that using the wood gas as alternative

  1. Simulation of fuel demand for wood-gas in combustion engine (United States)

    Botwinska, Katarzyna; Mruk, Remigiusz; Tucki, Karol; Wata, Mateusz


    In the era of the oil crisis and proceeding contamination of the natural environment, it is attempted to substitute fossil raw materials with alternative carriers. For many years, road transport has been considered as one of the main sources of the substances deteriorating air quality. Applicable European directives oblige the member states to implement biofuels and biocomponents into the general fuel market, however, such process is proceeding gradually and relatively slowly. So far, alternative fuels have been used on a large scale to substitute diesel fuel or petrol. Derivatives of vegetable raw materials, such as vegetable oils or their esters and ethanol extracted from biomass, are used to that end. It has been noticed that there is no alternative to LPG which, due to financial reasons, is more and more popular as fuel in passenger cars. In relation to solutions adopted in the past, it has been decided to analyse the option of powering a modern passenger car with wood gas - syngas. Such fuel has been practically used since the 1920's. To that end, a computer simulation created in SciLab environment was carried out. Passenger car Fiat Seicento, fitted with Fire 1.1 8V petrol engine with power of 40kW, whose parameters were used to prepare the model, was selected as the model vehicle. The simulation allows the determination of engine demand on the given fuel. Apart from the wood gas included in the title, petrol, methane and LPG were used. Additionally, the created model enables the determination of the engine power at the time of the indicated fuels supply. The results obtained in the simulation revealed considerable decrease in the engine power when the wood gas was supplied and the increased consumption of this fuel. On the basis of the analysis of the professional literature describing numerous inconveniences connected with the use of this fuel as well as the obtained results, it has been established that using the wood gas as alternative fuel is currently

  2. Medical imaging education in biomedical engineering curriculum: courseware development and application through a hybrid teaching model. (United States)

    Zhao, Weizhao; Li, Xiping; Chen, Hairong; Manns, Fabrice


    Medical Imaging is a key training component in Biomedical Engineering programs. Medical imaging education is interdisciplinary training, involving physics, mathematics, chemistry, electrical engineering, computer engineering, and applications in biology and medicine. Seeking an efficient teaching method for instructors and an effective learning environment for students has long been a goal for medical imaging education. By the support of NSF grants, we developed the medical imaging teaching software (MITS) and associated dynamic assessment tracking system (DATS). The MITS/DATS system has been applied to junior and senior medical imaging classes through a hybrid teaching model. The results show that student's learning gain improved, particularly in concept understanding and simulation project completion. The results also indicate disparities in subjective perception between junior and senior classes. Three institutions are collaborating to expand the courseware system and plan to apply it to different class settings.

  3. 76 FR 46769 - Applications for New Awards; Minority Science and Engineering Improvement Program (United States)


    ... science, technology, engineering, or mathematics (STEM) fields; or applications that develop articulation... in science, technology, engineering and mathematics. D. For cooperative projects grants, eligible... the fields of engineering or physical or biological sciences, compared to the average minority...

  4. Fluid Transport in Porous Media for Engineering Applications (United States)

    Benner, Eric Michael

    This doctoral dissertation presents three topics in modeling fluid transport through porous media used in engineering applications. The results provide insights into the design of fuel cell components, catalyst and drug delivery particles, and aluminum- based materials. Analytical and computational methods are utilized for the modeling of the systems of interest. Theoretical analysis of capillary-driven transport in porous media show that both geometric and evaporation effects significantly change the time dependent behavior of liquid imbibition and give a steady state flux into the medium. The evaporation-capillary number is significant in determining the time-dependent behavior of capillary flows in porous media. The analytical solutions for the front position for 1D and 2D capillary flows and under normal evaporation agree with experimental results. The lattice Boltzmann method (LBM) is used for versatile and flexible modeling of pore-scale phenomena in porous media. The LBM is used to show the the effects of various physical phenomena, such as multiphase, electrochemical, and dissolution, on pitting corrosion of aluminum surfaces in corrosive environments. In particular, each of these phenomena may spontaneously manifest phenomenological asymmetries that influence the growth of the corroding pit. Fluid motion in bimodal porous particles shows heterogeneous flow behavior in the medium. A brief discussion is given on implementations of parallel lattice Boltzmann schemes for future increase in simulation model capabilities. Each of these topic areas may be extended by further combining models of important physical phenomena. In the appendices, additional prospective results are overviewed. The font shape of capillary wicking from a finite line source into a 2D domain agrees qualitatively with empirical observations. A discussion of the background and application of the LBM to stress corrosion cracking in aluminum is given, where we show that thin cracks will

  5. Advances in biodiesel fuel for application in compression ignition engines

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Jo-Han; Ng, Hoon Kiat [University of Nottingham Malaysia Campus, Department of Mechanical, Materials and Manufacturing Engineering, Jalan Broga, Semenyih, Selangor (Malaysia); Gan, Suyin [University of Nottingham Malaysia Campus, Department of Chemical and Environmental Engineering, Jalan Broga, Semenyih, Selangor (Malaysia)


    The importance of biodiesel as a renewable and economically viable alternative to fossil diesel for applications in compression ignition (CI) engines has led to intense research in the field over the last two decades. This is predominantly due to the depletion of petroleum resources, and increasing awareness of environmental and health impacts from the combustion of fossil diesel. Biodiesel is favoured over other biofuels because of its compatibility with present day CI engines, with no further adjustments required to the core engine configurations when used in either neat or blended forms. Studies conducted to date on various CI engines fuelled with varying biodiesel types and blends under numerous test cycles have shown that key tailpipe pollutants, such as carbon monoxide, aromatics, sulphur oxides, unburnt hydrocarbons and particulate matters are potentially reduced. The effects of biodiesel on nitrogen oxides emission require further tests and validations. The improvement in most of the diesel emission species comes with a trade-off in a reduction of brake power and an increase in fuel consumption. Biodiesel's lubricating properties are generally better than those of its fossil diesel counterpart, which result in an increased engine life. These substantial differences in engine-out responses between biodiesel and fossil diesel combustion are mainly attributed to the physical properties and chemical composition of the fuels. Despite the purported benefits, widespread adoption of biodiesel usage in CI engines is hindered by outstanding technical challenges, such as low temperature inoperability, storage instabilities, in-cylinder carbon deposition and fuel line corrosion. It is imperative that these issues are addressed appropriately to ensure that long-term biodiesel usage in CI engines does not negatively affect the overall engine durability. Possible solutions range from biodiesel fuel reformulation through feedstock choice and production technique, to

  6. Computational engineering

    CERN Document Server


    The book presents state-of-the-art works in computational engineering. Focus is on mathematical modeling, numerical simulation, experimental validation and visualization in engineering sciences. In particular, the following topics are presented: constitutive models and their implementation into finite element codes, numerical models in nonlinear elasto-dynamics including seismic excitations, multiphase models in structural engineering and multiscale models of materials systems, sensitivity and reliability analysis of engineering structures, the application of scientific computing in urban water management and hydraulic engineering, and the application of genetic algorithms for the registration of laser scanner point clouds.

  7. Application of control theory to dynamic systems simulation (United States)

    Auslander, D. M.; Spear, R. C.; Young, G. E.


    The application of control theory is applied to dynamic systems simulation. Theory and methodology applicable to controlled ecological life support systems are considered. Spatial effects on system stability, design of control systems with uncertain parameters, and an interactive computing language (PARASOL-II) designed for dynamic system simulation, report quality graphics, data acquisition, and simple real time control are discussed.

  8. Application of Anova to Pulse Detonation Engine Dynamic Performance Measurements (United States)

    Chander, Subhash; Kumar, Rakesh; Sandhu, Manmohan; Jindal, TK


    Application of Anova to Pulse detonation engine dynamic performance measurement resulted in quantifying engine functionality during various operations. After evaluating the performance, techniques of improving it, were applied in multiple areas of relevant interest. This produced encouraging results and helped in upscaling efforts in a significant manner. The current paper deals in the details of anova implementation and systematic identification of key areas of improvements. The improvements were carried out after careful selection of plans in the engine, ground rig and instrumentation setup etc. It also yielded better reproducibility of performance and optimization of main subsystems of PDE. Further, this will also contribute to reduce the development cycle and trial complexity also, if researchers continue to extract concern areas to be addressed.

  9. [Plastid genome engineering: novel optimization strategies and applications]. (United States)

    Zhou, Fei; Lu, Shi-zhan; Gao, Liang; Zhang, Juan-juan; Lin, Yong-jun


    The plastid genome engineering system allows site-specific modifications via two homologous recombination events. It is much safer, more precise and efficient compared with the nuclear transformation system. This technology can be applied to the basic research to expand plastid genome function analysis, and it also provides an excellent platform for not only high-level production of recombinant proteins but also plant breeding. In this review, we summarize the state of the art and progresses in this field. We focus on novel breeding strategies in transformation system improvement and new tools to enhance plastid transgene expression levels. In addition, we highlight selected applications in resistance engineering and quality improvement via metabolic engineering. We believe that by overcoming current technological limitations in the plastid transformation system can another green revolution for crop breeding beckon.

  10. Genetic engineering of the chloroplast: novel tools and new applications. (United States)

    Bock, Ralph


    The plastid genome represents an attractive target of genetic engineering in crop plants. Plastid transgenes often give high expression levels, can be stacked in operons and are largely excluded from pollen transmission. Recent research has greatly expanded our toolbox for plastid genome engineering and many new proof-of-principle applications have highlighted the enormous potential of the transplastomic technology in both crop improvement and the development of plants as bioreactors for the sustainable and cost-effective production of biopharmaceuticals, enzymes and raw materials for the chemical industry. This review describes recent technological advances with plastid transformation in seed plants. It focuses on novel tools for plastid genome engineering and transgene expression and summarizes progress with harnessing the potential of plastid transformation in biotechnology. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Metabolic engineering of Yarrowia lipolytica for industrial applications. (United States)

    Zhu, Quinn; Jackson, Ethel N


    Yarrowia lipolytica is a safe and robust yeast that has a history of industrial applications. Its physiological, metabolic and genomic characteristics have made it a superior host for metabolic engineering. The results of optimizing internal pathways and introducing new pathways have demonstrated that Y. lipolytica can be a platform cell factory for cost-effective production of chemicals and fuels derived from fatty acids, lipids and acetyl-CoA. Two products have been commercialized from metabolically engineered Y. lipolytica strains producing high amounts of omega-3 eicosapentaenoic acid, and more products are on the way to be produced at industrial scale. Here we review recent progress in metabolic engineering of Y. lipolytica for production of biodiesel fuel, functional fatty acids and carotenoids. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  12. Block copolymer assisted refractive index engineering of metal oxides for applications in optical sensing (United States)

    Poole, Zsolt L.; Ohodnicki, Paul; Buric, Michael; Yan, Aidong; Riyadh, Shaymaa; Lin, Yuankun; Chen, Kevin P.


    We demonstrate that the refractive indices of important functional metal oxides (TiO2, SnO2, and ZnO) can be engineered "at will" for applications in photonics engineering. The tailoring of the refractive indices is accomplished by 3D nanostructuring in the sub-wavelength regime (50nm or less) using the method of block-copolymer templating combined with a low cost solution processing approach. Using this method, the index of refraction of the demonstrated metal oxides and their doped variants can be engineered to be as low as 1.25. We will present both numerical simulations and experimental data demonstrating the unrestricted integration of functional metal oxides with a D-shaped optical fiber for applications in chemical and biological sensing. Using the developed refractive index engineering scheme, we introduce a novel hydrogen sensor by integrating a palladium doped TiO2 nanomaterial with D-shaped optical fiber and provide sensor characterization up to 700°C for applications in the energy sector.

  13. EngineSim: Turbojet Engine Simulator Adapted for High School Classroom Use (United States)

    Petersen, Ruth A.


    EngineSim is an interactive educational computer program that allows users to explore the effect of engine operation on total aircraft performance. The software is supported by a basic propulsion web site called the Beginner's Guide to Propulsion, which includes educator-created, web-based activities for the classroom use of EngineSim. In addition, educators can schedule videoconferencing workshops in which EngineSim's creator demonstrates the software and discusses its use in the educational setting. This software is a product of NASA Glenn Research Center's Learning Technologies Project, an educational outreach initiative within the High Performance Computing and Communications Program.

  14. Computational Materials Science and Chemistry: Accelerating Discovery and Innovation through Simulation-Based Engineering and Science

    Energy Technology Data Exchange (ETDEWEB)

    Crabtree, George [Argonne National Lab. (ANL), Argonne, IL (United States); Glotzer, Sharon [University of Michigan; McCurdy, Bill [University of California Davis; Roberto, Jim [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)


    uncertainty in simulation and modeling. Uncertainty quantification becomes increasingly challenging as simulations become more complex. Robust and sustainable computational infrastructure, including software and applications. For modeling and simulation, software equals infrastructure. To validate the computational tools, software is critical infrastructure that effectively translates huge arrays of experimental data into useful scientific understanding. An integrated approach for managing this infrastructure is essential. Efficient transfer and incorporation of simulation-based engineering and science in industry. Strategies for bridging the gap between research and industrial applications and for widespread industry adoption of integrated computational materials engineering are needed.

  15. Diffusion in Liquids : Equilibrium Molecular Simulations and Predictive Engineering Models

    NARCIS (Netherlands)

    Liu, X.


    The aim of this thesis is to study multicomponent diffusion in liquids using Molecular Dynamics (MD) simulations. Diffusion plays an important role in mass transport processes. In binary systems, mass transfer processes have been studied extensively using both experiments and molecular simulations.

  16. Protein-hydrogel interactions in tissue engineering: mechanisms and applications. (United States)

    Zustiak, Silviya P; Wei, Yunqian; Leach, Jennie B


    Recent advances in our understanding of the sophistication of the cellular microenvironment and the dynamics of tissue remodeling during development, disease, and regeneration have increased our appreciation of the current challenges facing tissue engineering. As this appreciation advances, we are better equipped to approach problems in the biology and therapeutics of even more complex fields, such as stem cells and cancer. To aid in these studies, as well as the established areas of tissue engineering, including cardiovascular, musculoskeletal, and neural applications, biomaterials scientists have developed an extensive array of materials with specifically designed chemical, mechanical, and biological properties. Herein, we highlight an important topic within this area of biomaterials research, protein-hydrogel interactions. Due to inherent advantages of hydrated scaffolds for soft tissue engineering as well as specialized bioactivity of proteins and peptides, this field is well-posed to tackle major needs within emerging areas of tissue engineering. We provide an overview of the major modes of interactions between hydrogels and proteins (e.g., weak forces, covalent binding, affinity binding), examples of applications within growth factor delivery and three-dimensional scaffolds, and finally future directions within the area of hydrogel-protein interactions that will advance our ability to control the cell-biomaterial interface.

  17. Protein–Hydrogel Interactions in Tissue Engineering: Mechanisms and Applications (United States)

    Zustiak, Silviya P.; Wei, Yunqian


    Recent advances in our understanding of the sophistication of the cellular microenvironment and the dynamics of tissue remodeling during development, disease, and regeneration have increased our appreciation of the current challenges facing tissue engineering. As this appreciation advances, we are better equipped to approach problems in the biology and therapeutics of even more complex fields, such as stem cells and cancer. To aid in these studies, as well as the established areas of tissue engineering, including cardiovascular, musculoskeletal, and neural applications, biomaterials scientists have developed an extensive array of materials with specifically designed chemical, mechanical, and biological properties. Herein, we highlight an important topic within this area of biomaterials research, protein–hydrogel interactions. Due to inherent advantages of hydrated scaffolds for soft tissue engineering as well as specialized bioactivity of proteins and peptides, this field is well-posed to tackle major needs within emerging areas of tissue engineering. We provide an overview of the major modes of interactions between hydrogels and proteins (e.g., weak forces, covalent binding, affinity binding), examples of applications within growth factor delivery and three-dimensional scaffolds, and finally future directions within the area of hydrogel–protein interactions that will advance our ability to control the cell–biomaterial interface. PMID:23150926

  18. Rapid prototyping technology and its application in bone tissue engineering. (United States)

    Yuan, Bo; Zhou, Sheng-Yuan; Chen, Xiong-Sheng

    Bone defects arising from a variety of reasons cannot be treated effectively without bone tissue reconstruction. Autografts and allografts have been used in clinical application for some time, but they have disadvantages. With the inherent drawback in the precision and reproducibility of conventional scaffold fabrication techniques, the results of bone surgery may not be ideal. This is despite the introduction of bone tissue engineering which provides a powerful approach for bone repair. Rapid prototyping technologies have emerged as an alternative and have been widely used in bone tissue engineering, enhancing bone tissue regeneration in terms of mechanical strength, pore geometry, and bioactive factors, and overcoming some of the disadvantages of conventional technologies. This review focuses on the basic principles and characteristics of various fabrication technologies, such as stereolithography, selective laser sintering, and fused deposition modeling, and reviews the application of rapid prototyping techniques to scaffolds for bone tissue engineering. In the near future, the use of scaffolds for bone tissue engineering prepared by rapid prototyping technology might be an effective therapeutic strategy for bone defects.

  19. An Open Simulation System Model for Scientific Applications (United States)

    Williams, Anthony D.


    A model for a generic and open environment for running multi-code or multi-application simulations - called the open Simulation System Model (OSSM) - is proposed and defined. This model attempts to meet the requirements of complex systems like the Numerical Propulsion Simulator System (NPSS). OSSM places no restrictions on the types of applications that can be integrated at any state of its evolution. This includes applications of different disciplines, fidelities, etc. An implementation strategy is proposed that starts with a basic prototype, and evolves over time to accommodate an increasing number of applications. Potential (standard) software is also identified which may aid in the design and implementation of the system.

  20. The development and application of engineered proteins for bioremediation

    Energy Technology Data Exchange (ETDEWEB)

    Trewhella, J. [ed.


    Clean up of the toxic legacy of the Cold War is projected to be the most expensive domestic project the nation has yet undertaken. Remediation of the Department of Energy and Department of Defense toxic waste sites alone are projected to cost {approximately}$1 trillion over a 20-30 year period. New, cost effective technologies are needed to attack this enormous problem. Los Alamos has put together a cross-divisional team of scientist to develop science based bioremediation technology to work toward this goal. In the team we have expertise in: (1) molecular, ecosystem and transport modeling; (2) genetic and protein engineering; (3) microbiology and microbial ecology; (4) structural biology; and (5) bioinorganic chemistry. This document summarizes talks at a workshop of different aspects of bioremediation technology including the following: Introducing novel function into a Heme enzyme: engineering by excavation; cytochrome P-450: ideal systems for bioremediation?; selection and development of bacterial strains for in situ remediation of cholorinated solvents; genetic analysis and preparation of toluene ortho-monooxygenase for field application in remediation of trichloroethylene; microbial ecology and diversity important to bioremediation; engineering haloalkane dehalogenase for bioremediation; enzymes for oxidative biodegradation; indigenous bacteria as hosts for engineered proteins; performance of indigenous bacterial, hosting engineered proteins in microbial communities.

  1. Piezoelectric polymers as biomaterials for tissue engineering applications. (United States)

    Ribeiro, Clarisse; Sencadas, Vítor; Correia, Daniela M; Lanceros-Méndez, Senentxu


    Tissue engineering often rely on scaffolds for supporting cell differentiation and growth. Novel paradigms for tissue engineering include the need of active or smart scaffolds in order to properly regenerate specific tissues. In particular, as electrical and electromechanical clues are among the most relevant ones in determining tissue functionality in tissues such as muscle and bone, among others, electroactive materials and, in particular, piezoelectric ones, show strong potential for novel tissue engineering strategies, in particular taking also into account the existence of these phenomena within some specific tissues, indicating their requirement also during tissue regeneration. This referee reports on piezoelectric materials used for tissue engineering applications. The most used materials for tissue engineering strategies are reported together with the main achievements, challenges and future needs for research and actual therapies. This review provides thus a compilation of the most relevant results and strategies and a start point for novel research pathways in the most relevant and challenging open questions. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Enabling Aequorin for Biotechnology Applications Through Genetic Engineering. (United States)

    Grinstead, Kristen; Joel, Smita; Zingg, Jean-Marc; Dikici, Emre; Daunert, Sylvia


    In recent years, luminescent proteins have been studied for their potential application in a variety of detection systems. Bioluminescent proteins, which do not require an external excitation source, are especially well-suited as reporters in analytical detection. The photoprotein aequorin is a bioluminescent protein that can be engineered for use as a molecular reporter under a wide range of conditions while maintaining its sensitivity. Herein, the characteristics of aequorin as well as the engineering and production of aequorin variants and their impact on signal detection in biological systems are presented. The structural features and activity of aequorin, its benefits as a label for sensing and applications in highly sensitive detection, as well as in gaining insight into biological processes are discussed. Among those, focus has been placed on the highly sensitive calcium detection in vivo, in vitro DNA and small molecule sensing, and development of in vivo imaging technologies. Graphical Abstract.

  3. Silk Materials Functionalized via Genetic Engineering for Biomedical Applications. (United States)

    Deptuch, Tomasz; Dams-Kozlowska, Hanna


    The great mechanical properties, biocompatibility and biodegradability of silk-based materials make them applicable to the biomedical field. Genetic engineering enables the construction of synthetic equivalents of natural silks. Knowledge about the relationship between the structure and function of silk proteins enables the design of bioengineered silks that can serve as the foundation of new biomaterials. Furthermore, in order to better address the needs of modern biomedicine, genetic engineering can be used to obtain silk-based materials with new functionalities. Sequences encoding new peptides or domains can be added to the sequences encoding the silk proteins. The expression of one cDNA fragment indicates that each silk molecule is related to a functional fragment. This review summarizes the proposed genetic functionalization of silk-based materials that can be potentially useful for biomedical applications.

  4. Some design considerations for ceramic components in heat engine applications (United States)

    Gyekenyesi, John P.


    The design methodology for brittle material structures which is being developed and used at the Lewis Research Center for sizing ceramic components in heat engine applications is reviewed. Theoretical aspects of designing with structural ceramics are discussed, and a general purpose reliability program for predicting fast fracture response due to volume distributed flaws is described. Statistical treatment of brittle behavior, based on the Weibull model, is reviewed and its advantages, as well as drawbacks, are listed. A mechanistic statistical fracture theory, proposed by Batdorf to overcome the Weibull model limitations and based on Griffith fracture mechanics, is summarized. Failure probability predictions are made for rotating annular Si3N4 disks using various fracture models, and the results are compared to actual failure data. The application of these design methods to Government funded ceramics engine demonstration programs is surveyed. The uncertainty in observed component performance emphasizes the need for proof testing and improved nondestructive evaluation to guarantee adequate structural integrity.

  5. Applications of computational tools in biosciences and medical engineering

    CERN Document Server

    Altenbach, Holm


     This book presents the latest developments and applications of computational tools related to the biosciences and medical engineering. It also reports the findings of different multi-disciplinary research projects, for example, from the areas of scaffolds and synthetic bones, implants and medical devices, and medical materials. It is also shown that the application of computational tools often requires mathematical and experimental methods. Computational tools such as the finite element methods, computer-aided design and optimization as well as visualization techniques such as computed axial tomography open up completely new research fields that combine the fields of engineering and bio/medical. Nevertheless, there are still hurdles since both directions are based on quite different ways of education. Often even the “language” can vary from discipline to discipline.

  6. Simulation of Temperature Fluctuations in Stirling Engine Regenerator Matrices

    DEFF Research Database (Denmark)

    Andersen, Stig Kildegaard; Carlsen, Henrik; Thomsen, Per Grove


    The objective of this study has been to create a model for studying the effects of fluctuations in regenerator matrix temperatures on Stirling engine performance. A one-dimensional model with axial discretisation of engine components has been formulated using the balance equations for mass, energy...... an idealised model. Steady state periodic solutions to the model are found using a custom built shooting method that finds solutions that simultaneously satisfy cyclic boundary conditions and integral conditions. It has been found that true steady state periodic solutions to the model can be reliably...

  7. Microscale and nanoscale heat transfer fundamentals and engineering applications

    CERN Document Server

    Sobhan, CB


    Preface Introduction to Microscale Heat Transfer Microscale Heat Transfer: A Recent Avenue in Energy Transport State of the Art: Some Introductory Remarks Overview of Microscale Transport Phenomena Discussions on Size-Effect Behavior Fundamental Approach for Microscale Heat Transfer Introduction to Engineering Applications of Microscale Heat Transfer Microscale Heat Conduction Review of Conduction Heat Transfer Conduction at the Microscale Space and Timescales Fundamental Approach Thermal Conductivity Boltzmann Equation and Phonon Transport Conduction in Thin Films

  8. Sensors for in vitro bone tissue engineering applications


    Gustavsson, Mikael


    This doctoral thesis explores how ion sensors can provide spatial and temporal control of specific cellular and biomaterial activity related to bone tissue engineering applications. First it was investigated the influence of different osteoblast-like cell models on the ionic extracellular environment (IEE) in vitro. Rat-derived mesenchymal stem cells (rMSCs) and SAOS-2 cells were observed to express high alkaline phosphatase (ALP) activity, and as a consequence they increased the concentra...

  9. Magnesium incorporated chitosan based scaffolds for tissue engineering applications


    Adhikari, Udhab; Rijal, Nava P.; Khanal, Shalil; Pai, Devdas; Sankar, Jagannathan; Bhattarai, Narayan


    Chitosan based porous scaffolds are of great interest in biomedical applications especially in tissue engineering because of their excellent biocompatibility in vivo, controllable degradation rate and tailorable mechanical properties. This paper presents a study of the fabrication and characterization of bioactive scaffolds made of chitosan (CS), carboxymethyl chitosan (CMC) and magnesium gluconate (MgG). Scaffolds were fabricated by subsequent freezing-induced phase separation and lyophiliza...

  10. Web-Based Simulation Games for the Integration of Engineering and Business Fundamentals (United States)

    Calfa, Bruno; Banholzer, William; Alger, Monty; Doherty, Michael


    This paper describes a web-based suite of simulation games that have the purpose to enhance the chemical engineering curriculum with business-oriented decisions. Two simulation cases are discussed whose teaching topics include closing material and energy balances, importance of recycle streams, price-volume relationship in a dynamic market, impact…

  11. Modular simulation software development for liquid propellant rocket engines based on MATLAB Simulink

    Directory of Open Access Journals (Sweden)

    Naderi Mahyar


    Full Text Available Focusing on Liquid Propellant Rocket Engine (LPRE major components, a steady state modular simulation software has been established in MATLAB Simulink. For integrated system analysis, a new algorithm dependant on engine inlet mass flow rate and pressure is considered. Using the suggested algorithm, it is possible to evaluate engine component operation, similar to the known initial parameters during hot fire test of the engine on stand. As a case study, the reusable Space Shuttle Main Engine (SSME has been selected and the simulation has been performed to predict engine’s throttled operation at 109 percent of the nominal thrust value. For this purpose the engine actual flow diagram has been converted to 34 numerical modules and the engine has been modelled by solving a total of 101 steady state mathematic equations. The mean error of the simulation results is found to be less than 5% compared with the published SSME data. Using the presented idea and developed modules, it is possible to build up the numerical model and simulate other LPREs.

  12. A simulation based engineering method to support HAZOP studies

    DEFF Research Database (Denmark)

    Enemark-Rasmussen, Rasmus; Cameron, David; Angelo, Per Bagge


    HAZOP is the most commonly used process hazard analysis tool in industry, a systematic yet tedious and time consuming method. The aim of this study is to explore the feasibility of process dynamic simulations to facilitate the HAZOP studies. We propose a simulation-based methodology to complement...... the conventional HAZOP procedure. The method systematically generates failure scenarios by considering process equipment deviations with pre-defined failure modes. The effect of failure scenarios is then evaluated using dynamic simulations -in this study the K-Spice® software used. The consequences of each failure...... model as case study....

  13. Orthogonal polarization in lasers physical phenomena and engineering applications

    CERN Document Server

    Zhang, Shulian


    This practical book summarizes the latest research results of orthogonally polarized lasers, birefringence laser cavities, and their applications. Coverage ranges from basic principles and technologies to the characteristics of different cavities and lasers to various measurement techniques. A number of figures, experimental designs, and measurement curves are included, helping readers gain a thorough understanding of the many applications in modern engineering and start their own projects. Many types of relevant lasers (Helium/Neon lasers, Nd:YAG lasers, laser diodes, etc.) are also discussed

  14. Genetic engineering of cytokinins and their application to agriculture. (United States)

    Ma, Qing-Hu


    Cytokinins are master regulators of plant growth and development. They are involved in the regulation of many important physiological and metabolic processes. Recent progress in cytokinin research at the molecular level, including identification of related genes and cytokinin receptors, plus elucidation of signal transduction, has greatly increased our understanding of cytokinin actions. Although still in its infant stage, molecular breeding of crops with altered cytokinin metabolism, when combined with the transgenic approach, has shown very promising potential for application to agriculture. In this review we briefly introduce recent progress in cytokinin molecular biology, discuss applications of cytokinin genetic engineering to agriculture, and present implications and future research directions.

  15. Photonics applications and web engineering: WILGA Summer 2015 (United States)

    Romaniuk, Ryszard S.


    Wilga Summer 2015 Symposium on Photonics Applications and Web Engineering was held on 23-31 May. The Symposium gathered over 350 participants, mainly young researchers active in optics, optoelectronics, photonics, electronics technologies and applications. There were presented around 300 presentations in a few main topical tracks including: bio-photonics, optical sensory networks, photonics-electronics-mechatronics co-design and integration, large functional system design and maintenance, Internet of Thins, and other. The paper is an introduction the 2015 WILGA Summer Symposium Proceedings, and digests some of the Symposium chosen key presentations.

  16. Generalized Linear Models with Applications in Engineering and the Sciences

    CERN Document Server

    Myers, Raymond H; Vining, G Geoffrey; Robinson, Timothy J


    Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities."-Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Ma

  17. Geomagnetically induced currents: Science, engineering, and applications readiness (United States)

    Pulkkinen, A.; Bernabeu, E.; Thomson, A.; Viljanen, A.; Pirjola, R.; Boteler, D.; Eichner, J.; Cilliers, P. J.; Welling, D.; Savani, N. P.; Weigel, R. S.; Love, J. J.; Balch, C.; Ngwira, C. M.; Crowley, G.; Schultz, A.; Kataoka, R.; Anderson, B.; Fugate, D.; Simpson, J. J.; MacAlester, M.


    This paper is the primary deliverable of the very first NASA Living With a Star Institute Working Group, Geomagnetically Induced Currents (GIC) Working Group. The paper provides a broad overview of the current status and future challenges pertaining to the science, engineering, and applications of the GIC problem. Science is understood here as the basic space and Earth sciences research that allows improved understanding and physics-based modeling of the physical processes behind GIC. Engineering, in turn, is understood here as the "impact" aspect of GIC. Applications are understood as the models, tools, and activities that can provide actionable information to entities such as power systems operators for mitigating the effects of GIC and government agencies for managing any potential consequences from GIC impact to critical infrastructure. Applications can be considered the ultimate goal of our GIC work. In assessing the status of the field, we quantify the readiness of various applications in the mitigation context. We use the Applications Readiness Level (ARL) concept to carry out the quantification.

  18. Geomagnetically induced currents: Science, engineering, and applications readiness (United States)

    Pulkkinen, Antti; Bernabeu, E.; Thomson, A.; Viljanen, A.; Pirjola, R.; Boteler, D.; Eichner, J.; Cilliers, P.J.; Welling, D.; Savani, N.P.; Weigel, R.S.; Love, Jeffrey J.; Balch, Christopher; Ngwira, C.M.; Crowley, G.; Schultz, Adam; Kataoka, R.; Anderson, B.; Fugate, D.; Simpson, J.J.; MacAlester, M.


    This paper is the primary deliverable of the very first NASA Living With a Star Institute Working Group, Geomagnetically Induced Currents (GIC) Working Group. The paper provides a broad overview of the current status and future challenges pertaining to the science, engineering, and applications of the GIC problem. Science is understood here as the basic space and Earth sciences research that allows improved understanding and physics-based modeling of the physical processes behind GIC. Engineering, in turn, is understood here as the “impact” aspect of GIC. Applications are understood as the models, tools, and activities that can provide actionable information to entities such as power systems operators for mitigating the effects of GIC and government agencies for managing any potential consequences from GIC impact to critical infrastructure. Applications can be considered the ultimate goal of our GIC work. In assessing the status of the field, we quantify the readiness of various applications in the mitigation context. We use the Applications Readiness Level (ARL) concept to carry out the quantification.

  19. Progress in the field of electrospinning for tissue engineering applications. (United States)

    Agarwal, Seema; Wendorff, Joachim H; Greiner, Andreas


    Electrospinning is an extremely promising method for the preparation of tissue engineering (TE) scaffolds. This technique provides nonwovens resembling in their fibrillar structures those of the extracellular matrix (ECM), and offering large surface areas, ease of functionalization for various purposes, and controllable mechanical properties. The recent developments toward large-scale productions combined with the simplicity of the process render this technique very attractive. Progress concerning the use of electrospinning for TE applications has advanced impressively. Different groups have tackled the problem of electrospinning for TE applications from different angles. Nowadays, electrospinning of the majority of biodegradable and biocompatible polymers, either synthetic or natural, for TE applications is straightforward. Different issues, such as cell penetration, incorporation of growth and differentiating factors, toxicity of solvents used, productivity, functional gradient, etc. are main points of current considerations. The progress in the use of electrospinning for TE applications is highlighted in this article with focus on major problems encountered and on various solutions available until now.

  20. Technology Prospecting on Enzymes: Application, Marketing and Engineering

    Directory of Open Access Journals (Sweden)

    Shuang Li


    Full Text Available Enzymes are protein molecules functioning as specialized catalysts for chemical reactions. They have contributed greatly to the traditional and modern chemical industry by improving existing processes. In this article, we first give a survey of representative industrial applications of enzymes, focusing on the technical applications, feed industry, food processing and cosmetic products. The recent important developments and applications of enzymes in industry are reviewed. Then large efforts are dedicated to the worldwide enzyme market from the demand and production perspectives. Special attention is laid on the Chinese enzyme market. Although enzyme applications are being developed in full swing, breakthroughs are needed to overcome their weaknesses in maintaining activities during the catalytic processes. Strategies of metagomic analysis, cell surface display technology and cell-free system might give valuable solutions in novel enzyme exploiting and enzyme engineering.

  1. The Application of Simulation in Large Energy System Analysis

    Directory of Open Access Journals (Sweden)

    S.M. Divakaruni


    Full Text Available The Modular Modeling System (MMS developed by the Electric Power Research Institute (EPRI provides an efficient, economical, and user friendly computer code to engineers involved in the analysis of nuclear and fossil power plants. MMS will complement existing codes in the areas of nuclear and fossil power plant systems simulation. This paper provides a synopsis of MMS code features, development objectives, usage and results of fossil and nuclear plant simulation.

  2. The Application of Simulation in Large Energy System Analysis


    S.M. Divakaruni


    The Modular Modeling System (MMS) developed by the Electric Power Research Institute (EPRI) provides an efficient, economical, and user friendly computer code to engineers involved in the analysis of nuclear and fossil power plants. MMS will complement existing codes in the areas of nuclear and fossil power plant systems simulation. This paper provides a synopsis of MMS code features, development objectives, usage and results of fossil and nuclear plant simulation.

  3. Enhanced Discrete-Time Scheduler Engine for MBMS E-UMTS System Level Simulator

    DEFF Research Database (Denmark)

    Pratas, Nuno; Rodrigues, António


    In this paper the design of an E-UMTS system level simulator developed for the study of optimization methods for the MBMS is presented. The simulator uses a discrete event based philosophy, which captures the dynamic behavior of the Radio Network System. This dynamic behavior includes the user...... mobility, radio interfaces and the Radio Access Network. Its given emphasis on the enhancements developed for the simulator core, the Event Scheduler Engine. Two implementations for the Event Scheduler Engine are proposed, one optimized for single core processors and other for multi-core ones....

  4. Novel Engineered Refractory Materials for Advanced Reactor Applications

    Energy Technology Data Exchange (ETDEWEB)

    Shannon, Steven [North Carolina State Univ., Raleigh, NC (United States); Eapen, Jacob [North Carolina State Univ., Raleigh, NC (United States); Maria, Jon-Paul [North Carolina State Univ., Raleigh, NC (United States); Weber, William [Univ. of Tennessee, Knoxville, TN (United States)


    This report summarizes the results of DOE-NEUP grant 10-853. The project spanned 48 months (36 months under the original grant plus a 12 month no cost extension). The overarching goal of this work was to fabricate and characterize refractory materials engineered at the atomic scale with emphasis on their tolerance to accumulated radiation damage. With an emphasis on nano-scale structure, this work included atomic scale simulation to study the underlying mechanisms for modified radiation tolerance at these atomic scales.

  5. Engineering applications of fpgas chaotic systems, artificial neural networks, random number generators, and secure communication systems

    CERN Document Server

    Tlelo-Cuautle, Esteban; de la Fraga, Luis Gerardo


    This book offers readers a clear guide to implementing engineering applications with FPGAs, from the mathematical description to the hardware synthesis, including discussion of VHDL programming and co-simulation issues. Coverage includes FPGA realizations such as: chaos generators that are described from their mathematical models; artificial neural networks (ANNs) to predict chaotic time series, for which a discussion of different ANN topologies is included, with different learning techniques and activation functions; random number generators (RNGs) that are realized using different chaos generators, and discussions of their maximum Lyapunov exponent values and entropies. Finally, optimized chaotic oscillators are synchronized and realized to implement a secure communication system that processes black and white and grey-scale images. In each application, readers will find VHDL programming guidelines and computer arithmetic issues, along with co-simulation examples with Active-HDL and Simulink. Readers will b...

  6. Open source software engineering for geoscientific modeling applications (United States)

    Bilke, L.; Rink, K.; Fischer, T.; Kolditz, O.


    OpenGeoSys (OGS) is a scientific open source project for numerical simulation of thermo-hydro-mechanical-chemical (THMC) processes in porous and fractured media. The OGS software development community is distributed all over the world and people with different backgrounds are contributing code to a complex software system. The following points have to be addressed for successful software development: - Platform independent code - A unified build system - A version control system - A collaborative project web site - Continuous builds and testing - Providing binaries and documentation for end users OGS should run on a PC as well as on a computing cluster regardless of the operating system. Therefore the code should not include any platform specific feature or library. Instead open source and platform independent libraries like Qt for the graphical user interface or VTK for visualization algorithms are used. A source code management and version control system is a definite requirement for distributed software development. For this purpose Git is used, which enables developers to work on separate versions (branches) of the software and to merge those versions at some point to the official one. The version control system is integrated into an information and collaboration website based on a wiki system. The wiki is used for collecting information such as tutorials, application examples and case studies. Discussions take place in the OGS mailing list. To improve code stability and to verify code correctness a continuous build and testing system, based on the Jenkins Continuous Integration Server, has been established. This server is connected to the version control system and does the following on every code change: - Compiles (builds) the code on every supported platform (Linux, Windows, MacOS) - Runs a comprehensive test suite of over 120 benchmarks and verifies the results Runs software development related metrics on the code (like compiler warnings, code complexity

  7. A numerical simulation method and analysis of a complete thermoacoustic-Stirling engine. (United States)

    Ling, Hong; Luo, Ercang; Dai, Wei


    Thermoacoustic prime movers can generate pressure oscillation without any moving parts on self-excited thermoacoustic effect. The details of the numerical simulation methodology for thermoacoustic engines are presented in the paper. First, a four-port network method is used to build the transcendental equation of complex frequency as a criterion to judge if temperature distribution of the whole thermoacoustic system is correct for the case with given heating power. Then, the numerical simulation of a thermoacoustic-Stirling heat engine is carried out. It is proved that the numerical simulation code can run robustly and output what one is interested in. Finally, the calculated results are compared with the experiments of the thermoacoustic-Stirling heat engine (TASHE). It shows that the numerical simulation can agrees with the experimental results with acceptable accuracy.

  8. Solution-limited time stepping method and numerical simulation of single-element rocket engine combustor (United States)

    Lian, Chenzhou

    The focus of the research is to gain a better understanding of the mixing and combustion of propellants in a confined single element rocket engine combustor. The approach taken is to use the unsteady computational simulations of both liquid and gaseous oxygen reacting with gaseous hydrogen to study the effects of transient processes, recirculation regions and density variations under supercritical conditions. The physics of combustion involve intimate coupling between fluid dynamics, chemical kinetics and intense energy release and take place over an exceptionally wide range of scales. In the face of these monumental challenges, it remains the engineer's task to find acceptable simulation approach and reliable CFD algorithm for combustion simulations. To provide the computational robustness to allow detailed analyses of such complex problems, we start by investigating a method for enhancing the reliability of implicit computational algorithms and decreasing their sensitivity to initial conditions without adversely impacting their efficiency. Efficient convergence is maintained by specifying a large global CFL number while reliability is improved by limiting the local CFL number such that the solution change in any cell is less than a specified tolerance. The magnitude of the solution change is estimated from the calculated residual in a manner that requires negligible computational time. The method precludes unphysical excursions in Newton-like iterations in highly non-linear regions where Jacobians are changing rapidly as well as non-physical results during the computation. The method is tested against a series of problems to identify its characteristics and to verify the approach. The results reveal a substantial improvement in convergence reliability of implicit CFD applications that enables computations starting from simple initial conditions. The method is applied in the unsteady combustion simulations and allows long time running of the code without user

  9. Geant4-based Monte Carlo simulations on GPU for medical applications. (United States)

    Bert, Julien; Perez-Ponce, Hector; El Bitar, Ziad; Jan, Sébastien; Boursier, Yannick; Vintache, Damien; Bonissent, Alain; Morel, Christian; Brasse, David; Visvikis, Dimitris


    Monte Carlo simulation (MCS) plays a key role in medical applications, especially for emission tomography and radiotherapy. However MCS is also associated with long calculation times that prevent its use in routine clinical practice. Recently, graphics processing units (GPU) became in many domains a low cost alternative for the acquisition of high computational power. The objective of this work was to develop an efficient framework for the implementation of MCS on GPU architectures. Geant4 was chosen as the MCS engine given the large variety of physics processes available for targeting different medical imaging and radiotherapy applications. In addition, Geant4 is the MCS engine behind GATE which is actually the most popular medical applications' simulation platform. We propose the definition of a global strategy and associated structures for such a GPU based simulation implementation. Different photon and electron physics effects are resolved on the fly directly on GPU without any approximations with respect to Geant4. Validations have shown equivalence in the underlying photon and electron physics processes between the Geant4 and the GPU codes with a speedup factor of 80-90. More clinically realistic simulations in emission and transmission imaging led to acceleration factors of 400-800 respectively compared to corresponding GATE simulations.

  10. Applications of Simulation Technology - Pitfalls and Challenges

    Directory of Open Access Journals (Sweden)

    A.A. Malik


    Full Text Available Simulator based training has its own unique features and problems associated with it. There is a need to discuss these issues in order to understand the real meaning of simulator based training and to handle it effectively. Like other fields of training, use of simulation in the maritime industry is owing to the multiple factors covering technological, financial and training needs of the time. When properly used, supported by well trained and experienced instructors, simulator training, through its risk free environment, can contribute to a reduction in accidents and improve capability and efficiency, by providing trainees with the necessary experience and self confidence to carry out their roles, functions and tasks.

  11. Multitasking simulation: Present application and future directions. (United States)

    Adams, Traci Nicole; Rho, Jason C


    The Accreditation Council for Graduate Medical Education lists multi-tasking as a core competency in several medical specialties due to increasing demands on providers to manage the care of multiple patients simultaneously. Trainees often learn multitasking on the job without any formal curriculum, leading to high error rates. Multitasking simulation training has demonstrated success in reducing error rates among trainees. Studies of multitasking simulation demonstrate that this type of simulation is feasible, does not hinder the acquisition of procedural skill, and leads to better performance during subsequent periods of multitasking. Although some healthcare agencies have discouraged multitasking due to higher error rates among multitasking providers, it cannot be eliminated entirely in settings such as the emergency department in which providers care for more than one patient simultaneously. Simulation can help trainees to identify situations in which multitasking is inappropriate, while preparing them for situations in which multitasking is inevitable.

  12. Using Simulation to Increase Yields in Chemical Engineering

    Directory of Open Access Journals (Sweden)

    William C. Conley


    Full Text Available Trying to increase the yields or profit or efficiency (less pollution of chemical processes is a central goal of the chemical engineer in theory and practice. Certainly sound training in chemistry, business and pollution control help the engineer to set up optimal chemical processes. However, the ever changing demands of customers and business conditions, plus the multivariate complexity of the chemical business can make optimization challenging. Mathematical tools such as statistics and linear programming have certainly been useful to chemical engineers in their pursuit of optimal efficiency. However, some processes can be modeled linearly and some can not. Therefore, presented here will be an industrial chemical process with potentially five variables affecting the yield. Data from over one hundred runs of the process has been collected, but it is not known initially whether the yield relationship is linear or nonlinear. Therefore, the CTSP multivariate correlation coefficient will be calculated for the data to see if a relationship exists among the variables. Then once it is proven that there is a statistically significant relationship, an appropriate linear or nonlinear equation can be fitted to the data, and it can be optimized for use in the chemical plant.

  13. CRISPR Mediated Genome Engineering and its Application in Industry. (United States)

    Kaboli, Saeed; Babazada, Hasan


    The CRISPR (clustered regularly interspaced short palindromic repeat)-Cas9 (CRISPR-associated nuclease 9) method has been dramatically changing the field of genome engineering. It is a rapid, highly efficient and versatile tool for precise modification of genome that uses a guide RNA (gRNA) to target Cas9 to a specific sequence. This novel RNA-guided genome-editing technique has become a revolutionary tool in biomedical science and has many innovative applications in different fields. In this review, we briefly introduce the Cas9-mediated genome-editing tool, summarize the recent advances in CRISPR/Cas9 technology to engineer the genomes of a wide variety of organisms, and discuss their applications to treatment of fungal and viral disease. We also discuss advantageous of CRISPR/Cas9 technology to drug design, creation of animal model, and to food, agricultural and energy sciences. Adoption of the CRISPR/Cas9 technology in biomedical and biotechnological researches would create innovative applications of it not only for breeding of strains exhibiting desired traits for specific industrial and medical applications, but also for investigation of genome function.

  14. Applications of computational modeling in metabolic engineering of yeast. (United States)

    Kerkhoven, Eduard J; Lahtvee, Petri-Jaan; Nielsen, Jens


    Generally, a microorganism's phenotype can be described by its pattern of metabolic fluxes. Although fluxes cannot be measured directly, inference of fluxes is well established. In biotechnology the aim is often to increase the capacity of specific fluxes. For this, metabolic engineering methods have been developed and applied extensively. Many of these rely on balancing of intracellular metabolites, redox, and energy fluxes, using genome-scale models (GEMs) that in combination with appropriate objective functions and constraints can be used to predict potential gene targets for obtaining a preferred flux distribution. These methods point to strategies for altering gene expression; however, fluxes are often controlled by post-transcriptional events. Moreover, GEMs are usually not taking into account metabolic regulation, thermodynamics and enzyme kinetics. To facilitate metabolic engineering, tools from synthetic biology have emerged, enabling integration and assembly of naturally nonexistent, but well-characterized components into a living organism. To describe these systems kinetic models are often used and to integrate these systems with the standard metabolic engineering approach, it is necessary to expand the modeling of metabolism to consider kinetics of individual processes. This review will give an overview about models available for metabolic engineering of yeast and discusses their applications. © FEMS 2015. All rights reserved. For permissions, please e-mail:

  15. The System Concept and Its Application to Engineering

    CERN Document Server

    Aslaksen, Erik W


    Systems engineering is a mandatory approach in some industries, and is gaining wider acceptance for complex projects in general. However, under the imperative of delivering these projects on time and within budget, the focus has been mainly on the management aspects, with less attention to improving the core engineering activity – design. This book addresses the application of the system concept to design in several ways: by developing a deeper understanding of the system concept, by defining design and its characteristics within the process of engineering, and by applying the system concept to the early stage of design, where it has the greatest impact.   A central theme of the book is that the purpose of engineering is to be useful in meeting the needs of society, and that therefore the ultimate measure of the benefit of applying the system concept should be the extent to which it advances the achievement of that purpose. Consequently, any consistent, top-down development of the functionality required of...

  16. Research Application of Support Vector Machine in Fault Diagnosis of Certain Type Engine

    Directory of Open Access Journals (Sweden)

    Donghua FENG


    Full Text Available For the engine fault diagnosis in real problems, the number of samples available are limited, and the progress of research on the theory of the most limited to assume that the data samples, so that the network training data examples, in engineering applications has been slow, in this paper, the application of support vector machine in fault diagnosis of engine, the segmentation of the training sample set, in order to achieve the optimal analysis of the machine, the reasoning ability best. First introduced the two classification method of support vector machine and multi classification method based on two classification methods of the study, and applied to the fault diagnosis of engine, and then the simulation test for this method, and compared with the existing methods, the results show the effectiveness of the classification method, the results of the analysis also can use the tree diagram or table form, simple and intuitive; but also can save the contribution to some extent in time.

  17. Education and training of future nuclear engineers through the use of an interactive plant simulator

    Energy Technology Data Exchange (ETDEWEB)

    Ahnert, C.; Cuervo, D.; Garcia-Herranz, N.; Aragones, J.M.; Cabellos, O.; Gallego, E.; Minguez, E.; Lorente, A.; Piedra, D. [Departamento de Ingenieria Nuclear, Universidad Politecnica de Madrid, Jose Gutierrez Abascal 2, 28006 Madrid (Spain); Rebollo, L.; Blanco, J. [Gas Natural-Union FENOSA, Avda. de San Luis 77, 28033 Madrid (Spain)


    The International Atomic Energy Agency (IAEA) sponsors the development of nuclear reactor simulators for education, or arranges the supply of such simulation programs. Aware of this, the Department of Nuclear Engineering of the Universidad Politecnica de Madrid was provided in 2008 with the Interactive Graphical Simulator of the Spanish nuclear power plant Jose Cabrera, whose operation ceased definitively in 2006. According with the IAEA-TECDOC- 1411, the simulator is a Graphical Simulator, used for training of main control room personnel, technical support engineers, and operations management. This paper presents all the work performed at the Department to turn the simulator into a teaching/learning tool, to be use in the nuclear engineering studies following guidance found in: Shtub, A. Parush, T.T. Hewett 'The use of simulation in learning and teaching' (Int. J. Eng. Educ., 25(2), 2009, pp. 206-208). The experience obtained so far with the use of the simulator has been very successful. The graduate students involved in the development of the projects, practices and documents related with the simulator show a great interest for the work that they are doing making that the laboratory where the simulator is installed to be busy place. Regarding the undergraduate students, the practices in the simulator encourage them to follow the Nuclear Energy studies in the Engineering Schools, what is very rewarding for the Department professors. The simulator has proved to be an optimal tool to transfer the knowledge of the physical phenomena that are involved in the nuclear power plants, from the nuclear reactor to the whole set of systems and equipments on a nuclear power plant. It is also a relevant tool for motivation of the students, and to complete the theoretical lessons. This use of the simulator in the learning-teaching process meats also the criteria recommended for the Bologna adapted studies, as it helps to increase the private hands-on work of the

  18. Ionic Liquids as Novel Lubricants and Additives for Diesel Engine Applications

    Energy Technology Data Exchange (ETDEWEB)

    Qu, Jun [ORNL; Blau, Peter Julian [ORNL; Dai, Sheng [ORNL; Luo, Huimin [ORNL; Meyer III, Harry M [ORNL


    The lubricating properties of two ionic liquids with the same anion but different cations, one ammonium IL [C8H17]3NH.Tf2N and one imidazolium IL C10mim.Tf2N, were evaluated both in neat form and as oil additives. Experiments were conducted using a standardized reciprocating sliding test using a segment of a Cr-plated diesel engine piston ring against a grey cast iron flat specimen with simulated honing marks as on the engine cylinder liner. The selected ionic liquids were benchmarked against conventional hydrocarbon oils. Substantial friction and wear reductions, up to 55% and 34%, respectively, were achieved for the neat ionic liquids compared to a fully-formulated 15W40 engine oil. Adding 5 vol% ILs into mineral oil has demonstrated significant improvement in the lubricity. One blend even outperformed the 15W40 engine oil with 9% lower friction and 34% less wear. Lubrication regime modeling, worn surface morphology examination, and surface chemical analysis were conducted to help understand the lubricating mechanisms for ionic liquids. Results suggest great potential for using ionic liquids as base lubricants or lubricant additives for diesel engine applications.

  19. Application and Evaluation of Control Modes for Risk-Based Engine Performance Enhancements (United States)

    Liu, Yuan; Litt, Jonathan S.; Sowers, T. Shane; Owen, A. Karl; Guo, Ten-Huei


    The engine control system for civil transport aircraft imposes operational limits on the propulsion system to ensure compliance with safety standards. However, during certain emergency situations, aircraft survivability may benefit from engine performance beyond its normal limits despite the increased risk of failure. Accordingly, control modes were developed to improve the maximum thrust output and responsiveness of a generic high-bypass turbofan engine. The algorithms were designed such that the enhanced performance would always constitute an elevation in failure risk to a consistent predefined likelihood. This paper presents an application of these risk-based control modes to a combined engine/aircraft model. Through computer and piloted simulation tests, the aim is to present a notional implementation of these modes, evaluate their effects on a generic airframe, and demonstrate their usefulness during emergency flight situations. Results show that minimal control effort is required to compensate for the changes in flight dynamics due to control mode activation. The benefits gained from enhanced engine performance for various runway incursion scenarios are investigated. Finally, the control modes are shown to protect against potential instabilities during propulsion-only flight where all aircraft control surfaces are inoperable.

  20. Applications of Ecological Engineering Remedies for Uranium Processing Sites, USA

    Energy Technology Data Exchange (ETDEWEB)

    Waugh, William [Navarro Research and Engineering


    The U.S. Department of Energy (USDOE) is responsible for remediation of environmental contamination and long-term stewardship of sites associated with the legacy of nuclear weapons production during the Cold War in the United States. Protection of human health and the environment will be required for hundreds or even thousands of years at many legacy sites. USDOE continually evaluates and applies advances in science and technology to improve the effectiveness and sustainability of surface and groundwater remedies (USDOE 2011). This paper is a synopsis of ecological engineering applications that USDOE is evaluating to assess the effectiveness of remedies at former uranium processing sites in the southwestern United States. Ecological engineering remedies are predicated on the concept that natural ecological processes at legacy sites, once understood, can be beneficially enhanced or manipulated. Advances in tools for characterizing key processes and for monitoring remedy performance are demonstrating potential. We present test cases for four ecological engineering remedies that may be candidates for international applications.

  1. [Application and potential of genome engineering by artificial enzymes]. (United States)

    Nomura, Wataru


    Artificial zinc finger proteins (ZFPs) consist of Cys2-His2-type modules composed of approximately 30 amino acids that adopt a ββα structure and coordinate a zinc ion. ZFPs recognizing specific DNA target sequences can substitute for the binding domains of various DNA-modifying enzymes to create designer nucleases, recombinases, and methylases with programmable sequence specificity. Enzymatic genome editing and modification can be applied to many fields of basic research and medicine. The recent development of new platforms using transcription activator-like effector (TALE) proteins or the clustered regularly interspaced short palindromic repeats/CRISPR-associated protein (CRISPR/Cas) system has expanded the range of possibilities for genome-editing technologies. These technologies empower investigators with the ability to efficiently knockout or regulate the functions of genes of interest. In this review, we discuss historical advancements in artificial ZFP applications and important issues that may influence the future of genome editing and engineering technologies. The development of artificial ZFPs has greatly increased the feasibility of manipulating endogenous gene functions through transcriptional control and gene modification. Advances in the ZFP, TALE, and CRISPR/Cas platforms have paved the way for the next generation of genome engineering approaches. Perspectives for the future of genome engineering are also discussed, including applications of targeting specific genomic alleles and studies in synthetic biology.

  2. NeuroManager: a workflow analysis based simulation management engine for computational neuroscience. (United States)

    Stockton, David B; Santamaria, Fidel


    We developed NeuroManager, an object-oriented simulation management software engine for computational neuroscience. NeuroManager automates the workflow of simulation job submissions when using heterogeneous computational resources, simulators, and simulation tasks. The object-oriented approach (1) provides flexibility to adapt to a variety of neuroscience simulators, (2) simplifies the use of heterogeneous computational resources, from desktops to super computer clusters, and (3) improves tracking of simulator/simulation evolution. We implemented NeuroManager in MATLAB, a widely used engineering and scientific language, for its signal and image processing tools, prevalence in electrophysiology analysis, and increasing use in college Biology education. To design and develop NeuroManager we analyzed the workflow of simulation submission for a variety of simulators, operating systems, and computational resources, including the handling of input parameters, data, models, results, and analyses. This resulted in 22 stages of simulation submission workflow. The software incorporates progress notification, automatic organization, labeling, and time-stamping of data and results, and integrated access to MATLAB's analysis and visualization tools. NeuroManager provides users with the tools to automate daily tasks, and assists principal investigators in tracking and recreating the evolution of research projects performed by multiple people. Overall, NeuroManager provides the infrastructure needed to improve workflow, manage multiple simultaneous simulations, and maintain provenance of the potentially large amounts of data produced during the course of a research project.

  3. NeuroManager: A workflow analysis based simulation management engine for computational neuroscience

    Directory of Open Access Journals (Sweden)

    David Bruce Stockton


    Full Text Available We developed NeuroManager, an object-oriented simulation management software engine for computational neuroscience. NeuroManager automates the workflow of simulation job submissions when using heterogeneous computational resources, simulators, and simulation tasks. The object-oriented approach 1 provides flexibility to adapt to a variety of neuroscience simulators, 2 simplifies the use of heterogeneous computational resources, from desktops to super computer clusters, and 3 improves tracking of simulator/simulation evolution. We implemented NeuroManager in Matlab, a widely used engineering and scientific language, for its signal and image processing tools, prevalence in electrophysiology analysis, and increasing use in college Biology education. To design and develop NeuroManager we analyzed the workflow of simulation submission for a variety of simulators, operating systems, and computational resources, including the handling of input parameters, data, models, results, and analyses. This resulted in twenty-two stages of simulation submission workflow. The software incorporates progress notification, automatic organization, labeling, and time-stamping of data and results, and integrated access to Matlab's analysis and visualization tools. NeuroManager provides users with the tools to automate daily tasks, and assists principal investigators in tracking and recreating the evolution of research projects performed by multiple people. Overall, NeuroManager provides the infrastructure needed to improve workflow, manage multiple simultaneous simulations, and maintain provenance of the potentially large amounts of data produced during the course of a research project.

  4. Simulation of Cycle-to-Cycle Variation in Dual-Fuel Engines

    KAUST Repository

    Jaasim, Mohammed


    Standard practices of internal combustion (IC) engine experiments are to conduct the measurements of quantities averaged over a large number of cycles. Depending on the operating conditions, the cycle-to-cycle variation (CCV) of quantities, such as the indicated mean effective pressure (IMEP) are observed at different levels. Accurate prediction of CCV in IC engines is an important but challenging task. Computational fluid dynamics (CFD) simulations using high performance computing (HPC) can be used effectively to visualize such 3D spatial distributions. In the present study, a dual fuel large engine is considered, with natural gas injected into the manifold accompanied with direct injection of diesel pilot fuel to trigger ignition. Multiple engine cycles in 3D are simulated in series as in the experiments to investigate the potential of HPC based high fidelity simulations to accurately capture the cycle to cycle variation in dual fuel engines. Open cycle simulations are conducted to predict the combined effect of the stratification of fuel-air mixture, temperature and turbulence on the CCV of pressure. The predicted coefficient of variation (COV) of pressure compared to the results from closed cycle simulations and the experiments.

  5. Nanocomposite Hydrogels and Their Applications in Tissue Engineering. (United States)

    Motealleh, Andisheh; Kehr, Nermin Seda


    Nanocomposite (NC) hydrogels, organic-inorganic hybrid materials, are of great interest as artificial three-dimensional (3D) biomaterials for biomedical applications. NC hydrogels are prepared in water by chemically or physically cross-linking organic polymers with nanomaterials (NMs). The incorporation of hard inorganic NMs into the soft organic polymer matrix enhances the physical, chemical, and biological properties of NC hydrogels. Therefore, NC hydrogels are excellent candidates for artificial 3D biomaterials, particularly in tissue engineering applications, where they can mimic the chemical, mechanical, electrical, and biological properties of native tissues. A wide range of functional NMs and synthetic or natural organic polymers have been used to design new NC hydrogels with novel properties and tailored functionalities for biomedical uses. Each of these approaches can improve the development of NC hydrogels and, thus, provide advanced 3D biomaterials for biomedical applications. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  6. Virtual reality simulators for rock engineering related training.

    CSIR Research Space (South Africa)

    Squelch, A


    Full Text Available Virtual reality (VR) has been investigated by SIMRAC and CSIR Miningtek as a means of providing an enhancement to current training methods that will lead to more effective hazard awareness training programmes. A VR training simulator developed under...

  7. Coalbed gas content simulation test and application

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, S. [New Star Petroleum Company, Zhengzhou (China). North China Petroleum Bureau


    With a high-pressure canister and accurate thermoregulation system of IS-100 isotherm instrument and an electronic flow meter, a coalbed gas content simulation method is established. A control program is combined with it to control data acquisition. The method simulates the whole process of gas content measurement from coring to the completion of desorption. It enables the understanding of gas desorption regularities, and for obtaining the volume of gas loss at any one time. The study would be useful for comparing the various approaches of calculating gas loss volume. 3 refs., 5 figs.

  8. Intelligent computer systems in engineering design principles and applications

    CERN Document Server

    Sunnersjo, Staffan


    This introductory book discusses how to plan and build useful, reliable, maintainable and cost efficient computer systems for automated engineering design. The book takes a user perspective and seeks to bridge the gap between texts on principles of computer science and the user manuals for commercial design automation software. The approach taken is top-down, following the path from definition of the design task and clarification of the relevant design knowledge to the development of an operational system well adapted for its purpose. This introductory text for the practicing engineer working in industry covers most vital aspects of planning such a system. Experiences from applications of automated design systems in practice are reviewed based on a large number of real, industrial cases. The principles behind the most popular methods in design automation are presented with sufficient rigour to give the user confidence in applying them on real industrial problems. This book is also suited for a half semester c...

  9. Computational intelligence in time series forecasting theory and engineering applications

    CERN Document Server

    Palit, Ajoy K


    Foresight in an engineering enterprise can make the difference between success and failure, and can be vital to the effective control of industrial systems. Applying time series analysis in the on-line milieu of most industrial plants has been problematic owing to the time and computational effort required. The advent of soft computing tools offers a solution. The authors harness the power of intelligent technologies individually and in combination. Examples of the particular systems and processes susceptible to each technique are investigated, cultivating a comprehensive exposition of the improvements on offer in quality, model building and predictive control and the selection of appropriate tools from the plethora available. Application-oriented engineers in process control, manufacturing, production industry and research centres will find much to interest them in this book. It is suitable for industrial training purposes, as well as serving as valuable reference material for experimental researchers.

  10. The applicability of chemical alternatives assessment for engineered nanomaterials

    DEFF Research Database (Denmark)

    Hjorth, Rune; Hansen, Steffen Foss; Jacobs, Molly


    The use of alternatives assessment to substitute hazardous chemicals with inherently safer options is gaining momentum worldwide as a legislative and corporate strategy to minimize consumer, occupational, and environmental risks. Engineered nanomaterials represent an interesting case for alternat......The use of alternatives assessment to substitute hazardous chemicals with inherently safer options is gaining momentum worldwide as a legislative and corporate strategy to minimize consumer, occupational, and environmental risks. Engineered nanomaterials represent an interesting case...... for alternatives assessment approaches as they can be considered both emerging “chemicals” of concern, as well as potentially safer alternatives to hazardous chemicals. However, comparing the hazards of nanomaterials to traditional chemicals or to other nanomaterials is challenging and critical elements...... in chemical hazard and exposure assessment may have to be fundamentally altered to sufficiently address nanomaterials. The aim of this paper is to assess the overall applicability of alternatives assessment methods for nanomaterials and outline recommendations to enhance their use in this context. This paper...

  11. Mobile Timekeeping Application Built on Reverse-Engineered JPL Infrastructure (United States)

    Witoff, Robert J.


    Every year, non-exempt employees cumulatively waste over one man-year tracking their time and using the timekeeping Web page to save those times. This app eliminates this waste. The innovation is a native iPhone app. Libraries were built around a reverse- engineered JPL API. It represents a punch-in/punch-out paradigm for timekeeping. It is accessible natively via iPhones, and features ease of access. Any non-exempt employee can natively punch in and out, as well as save and view their JPL timecard. This app is built on custom libraries created by reverse-engineering the standard timekeeping application. Communication is through custom libraries that re-route traffic through BrowserRAS (remote access service). This has value at any center where employees track their time.

  12. Magnetic Resonance Imaging and Velocity Mapping in Chemical Engineering Applications. (United States)

    Gladden, Lynn F; Sederman, Andrew J


    This review aims to illustrate the diversity of measurements that can be made using magnetic resonance techniques, which have the potential to provide insights into chemical engineering systems that cannot readily be achieved using any other method. Perhaps the most notable advantage in using magnetic resonance methods is that both chemistry and transport can be followed in three dimensions, in optically opaque systems, and without the need for tracers to be introduced into the system. Here we focus on hydrodynamics and, in particular, applications to rheology, pipe flow, and fixed-bed and gas-solid fluidized bed reactors. With increasing development of industrially relevant sample environments and undersampling data acquisition strategies that can reduce acquisition times to chemical engineering research.

  13. An engineered plant peroxisome and its application in biotechnology. (United States)

    Kessel-Vigelius, Sarah K; Wiese, Jan; Schroers, Martin G; Wrobel, Thomas J; Hahn, Florian; Linka, Nicole


    Plant metabolic engineering is a promising tool for biotechnological applications. Major goals include enhancing plant fitness for an increased product yield and improving or introducing novel pathways to synthesize industrially relevant products. Plant peroxisomes are favorable targets for metabolic engineering, because they are involved in diverse functions, including primary and secondary metabolism, development, abiotic stress response, and pathogen defense. This review discusses targets for manipulating endogenous peroxisomal pathways, such as fatty acid β-oxidation, or introducing novel pathways, such as the synthesis of biodegradable polymers. Furthermore, strategies to bypass peroxisomal pathways for improved energy efficiency and detoxification of environmental pollutants are discussed. In sum, we highlight the biotechnological potential of plant peroxisomes and indicate future perspectives to exploit peroxisomes as biofactories. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

  14. Elements of quantum computing history, theories and engineering applications

    CERN Document Server

    Akama, Seiki


    A quantum computer is a computer based on a computational model which uses quantum mechanics, which is a subfield of physics to study phenomena at the micro level. There has been a growing interest on quantum computing in the 1990's, and some quantum computers at the experimental level were recently implemented. Quantum computers enable super-speed computation, and can solve some important problems whose solutions were regarded impossible or intractable with traditional computers. This book provides a quick introduction to quantum computing for readers who have no backgrounds of both theory of computation and quantum mechanics. “Elements of Quantum Computing” presents the history, theories, and engineering applications of quantum computing. The book is suitable to computer scientists, physicist, and software engineers.

  15. Engineering the Bacterial Microcompartment Domain for Molecular Scaffolding Applications

    Directory of Open Access Journals (Sweden)

    Eric J. Young


    Full Text Available As synthetic biology advances the intricacy of engineered biological systems, the importance of spatial organization within the cellular environment must not be marginalized. Increasingly, biological engineers are investigating means to control spatial organization within the cell, mimicking strategies used by natural pathways to increase flux and reduce cross-talk. A modular platform for constructing a diverse set of defined, programmable architectures would greatly assist in improving yields from introduced metabolic pathways and increasing insulation of other heterologous systems. Here, we review recent research on the shell proteins of bacterial microcompartments and discuss their potential application as “building blocks” for a range of customized intracellular scaffolds. We summarize the state of knowledge on the self-assembly of BMC shell proteins and discuss future avenues of research that will be important to realize the potential of BMC shell proteins as predictively assembling and programmable biological materials for bioengineering.

  16. Nonparametric statistics with applications to science and engineering

    CERN Document Server

    Kvam, Paul H


    A thorough and definitive book that fully addresses traditional and modern-day topics of nonparametric statistics This book presents a practical approach to nonparametric statistical analysis and provides comprehensive coverage of both established and newly developed methods. With the use of MATLAB, the authors present information on theorems and rank tests in an applied fashion, with an emphasis on modern methods in regression and curve fitting, bootstrap confidence intervals, splines, wavelets, empirical likelihood, and goodness-of-fit testing. Nonparametric Statistics with Applications to Science and Engineering begins with succinct coverage of basic results for order statistics, methods of categorical data analysis, nonparametric regression, and curve fitting methods. The authors then focus on nonparametric procedures that are becoming more relevant to engineering researchers and practitioners. The important fundamental materials needed to effectively learn and apply the discussed methods are also provide...

  17. Decomposition techniques in mathematical programming engineering and science applications

    CERN Document Server

    Conejo, Antonio J; Minguez, Roberto; Garcia-Bertrand, Raquel


    Optimization plainly dominates the design, planning, operation, and c- trol of engineering systems. This is a book on optimization that considers particular cases of optimization problems, those with a decomposable str- ture that can be advantageously exploited. Those decomposable optimization problems are ubiquitous in engineering and science applications. The book considers problems with both complicating constraints and complicating va- ables, and analyzes linear and nonlinear problems, with and without in- ger variables. The decomposition techniques analyzed include Dantzig-Wolfe, Benders, Lagrangian relaxation, Augmented Lagrangian decomposition, and others. Heuristic techniques are also considered. Additionally, a comprehensive sensitivity analysis for characterizing the solution of optimization problems is carried out. This material is particularly novel and of high practical interest. This book is built based on many clarifying, illustrative, and compu- tional examples, which facilitate the learning p...

  18. The concepts and applications of tissue engineering in otorhinolaryngology. (United States)

    Ribeiro, Leandro; Castro, Eugénia; Ferreira, Manuela; Helena, Diamantino; Robles, Raquel; Faria E Almeida, António; Condé, Artur


    Tissue engineering is a rapidly developing field that, making biological substitutes for the repair and regeneration of damaged tissues, will play an important role in the future of otorhinolaryngology. In this article we explain the principles of regenerative medicine and its potential applications in Otorhinolaryngology. The authors searched the published literature on this topic, chose relevant references, and extracted and systematized the data. There are some exciting possibilities for future treatments in otorhinolaryngology applying the concepts of tissue engineering. Copyright © 2014 Elsevier España, S.L.U. and Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial. All rights reserved.

  19. In vitro immersion studies of optimized electrospun bioglass 45S5 fibers for tissue engineering application (United States)

    Durgalakshmi, D.; Balakumar, S.


    Bioactive-glass scaffolds are crucial in bone tissue engineering application since, they work as temporary templates for tissue regrowth and provides structural support to the cells. However, many issues remain unfolded with regard to their design. In this study, for the first time bioactive glass 45S5 fibers were synthesized using electrospinning technique. The electrospinning process parameters were optimized to obtain reproducible fibers. The effect of solvent concentration and polymer concentration on fiber formation was clearly studied. In vitro studies in simulated body fluid (SBF) were performed to investigate the bioactivity and mineralization of the scaffold by inducing the formation of hydroxyapatite (HA) crystals.

  20. Mathematical Modeling and Simulation Introduction for Scientists and Engineers

    CERN Document Server

    Velten, Kai


    This concise and clear introduction to the topic requires only basic knowledge of calculus and linear algebra—all other concepts and ideas are developed in the course of the book. Lucidly written so as to appeal to undergraduates and practitioners alike, it enables readers to set up simple mathematical models on their own and to interpret their results and those of others critically. To achieve this, many examples have been chosen from various fields, such as biology, ecology, economics, medicine, agricultural, chemical, electrical, mechanical and process engineering, which are subsequently di

  1. A Perspective on Bionanosensor Simulation & Computational Enzyme Engineering

    DEFF Research Database (Denmark)

    Hediger, Martin Robert

    helps in optimizing such sensors. In the second project, Computational Enzyme Engineering, a method is developed which can be used to calculate the reaction barrier of a large number of enzyme mutants. First technical details are discussed, then we compare to experiments from Novozymes A/S and show how...... accurate the method is. Finally we use the method to calcualte the rate-limiting step in the reaction profile of around 400 mutants of an enzyme. This is the first time that the barrier of the rate-determining step is alculated in as set of mutants of this size, consisting of the full enzyme structure...

  2. Computational fluid dynamics simulation of the air/suppressant flow in an uncluttered F18 engine nacelle

    Energy Technology Data Exchange (ETDEWEB)

    Lopez, A.R.; Gritzo, L.A.; Hassan, B.


    For the purposes of designing improved Halon-alternative fire suppression strategies for aircraft applications, Computational Fluid Dynamics (CFD) simulations of the air flow, suppressant transport, and air-suppressant mixing within an uncluttered F18 engine nacelle were performed. The release of inert gases from a Solid Propellant Gas Generator (SPGG) was analyzed at two different injection locations in order to understand the effect of injection position on the flow patterns and the mixing of air and suppression agent. An uncluttered engine nacelle was simulated to provide insight into the global flow features as well as to promote comparisons with previous nacelle fire tests and recent water tunnel tests which included little or no clutter. Oxygen concentration levels, fuel/air residence times that would exist if a small fuel leak were present, velocity contours, and streamline patterns are presented inside the engine nacelle. The numerical results show the influence of the gent release location on regions of potential flame extinction due to oxygen inerting and high flame strain. The occurrence of inflow through the exhaust ducts on the aft end of the nacelle is also predicted. As expected, the predicted oxygen concentration levels were consistently higher than the measured levels since a fire was not modeled in this analysis. Despite differences in the conditions of these simulations and the experiments, good agreement was obtained between the CFD predictions and the experimental measurements.

  3. Large-eddy simulations of turbulent flows in internal combustion engines (United States)

    Banaeizadeh, Araz

    evaporated fuel mass fractions as predicted by the LES-FD and FMDF-MC for both reacting and non-reacting cases are shown to be consistent inside the RCM. Several non-reacting and reacting flows relevant to IC engines are also simulated with the new two-phase LES/FMDF model. The non-reacting flows in three geometrical configurations are considered: (1) a poppet valve in a sudden expansion, (2) a simple piston-cylinder assembly with a stationary open valve and harmonically moving flat piston, and (3) a realistic 3-valve single-cylinder direct-injection spark-ignition engine. The first and the second configurations are considered for validation of LES and for better understanding of the large-scale unsteady flow motions around the valve in the cylinder as generated by the piston movement. The predicted flow statistics by LES for the first two configurations compare well with the available experimental data. The LES results for third flow configuration show significant cycle-to-cycle variations (CCV) in the velocity field but insignificant CCV in the thermodynamic variables. During the intake stroke, the in-cylinder flow is highly inhomogeneous and turbulent, but during the compression stroke the flow becomes more homogeneous as turbulent decays. Turbulent mixing and combustion (with and without spray) in the 3-valve engine are simulated using the new two-phase compressible LES/FMDF model. Consistency of LES and FMDF results for single-phase reacting flows without spray but with flame ignition and premixed flame propagation, and two-phase reacting flows with spray, mixing and non-premixed combustion indicates the applicability and accuracy of the LES/FMDF model for complex turbulent combustion systems with moving boundaries.

  4. Transferable and flexible thin film devices for engineering applications (United States)

    Mutyala, Madhu Santosh K.; Zhou, Jingzhou; Li, Xiaochun


    Thin film devices can be of significance for manufacturing, energy conversion systems, solid state electronics, wireless applications, etc. However, these thin film sensors/devices are normally fabricated on rigid silicon substrates, thus neither flexible nor transferrable for engineering applications. This paper reports an innovative approach to transfer polyimide (PI) embedded thin film devices, which were fabricated on glass, to thin metal foils. Thin film thermocouples (TFTCs) were fabricated on a thin PI film, which was spin coated and cured on a glass substrate. Another layer of PI film was then spin coated again on TFTC/PI and cured to obtain the embedded TFTCs. Assisted by oxygen plasma surface coarsening of the PI film on the glass substrate, the PI embedded TFTC was successfully transferred from the glass substrate to a flexible copper foil. To demonstrate the functionality of the flexible embedded thin film sensors, they were transferred to the sonotrode tip of an ultrasonic metal welding machine for in situ process monitoring. The dynamic temperatures near the sonotrode tip were effectively measured under various ultrasonic vibration amplitudes. This technique of transferring polymer embedded electronic devices onto metal foils yield great potentials for numerous engineering applications.

  5. Interatomic bonding in solids fundamentals, simulation, applications

    CERN Document Server

    Levitin , Valim


    The connection between the quantum behavior of the structure elements of a substance and the parameters that determine the macroscopic behavior of materials has a major influence on the properties exhibited by different solids. Although quantum engineering and theory should complement each other, this is not always the case. This book aims to demonstrate how the properties of materials can be derived and predicted from the features of their structural elements, generally electrons. In a sense, electronic structure forms the glue holding solids together and it is central to determining struct


    NARCIS (Netherlands)


    A survey is given of Quantum Monte Carlo methods currently used to simulate quantum lattice models. The formalisms employed to construct the simulation algorithms are sketched. The origin of fundamental (minus sign) problems which limit the applicability of the Quantum Monte Carlo approach is shown

  7. Quantum Monte Carlo Simulations : Algorithms, Limitations and Applications

    NARCIS (Netherlands)

    Raedt, H. De


    A survey is given of Quantum Monte Carlo methods currently used to simulate quantum lattice models. The formalisms employed to construct the simulation algorithms are sketched. The origin of fundamental (minus sign) problems which limit the applicability of the Quantum Monte Carlo approach is shown

  8. Application of wildfire simulation models for risk analysis (United States)

    Alan A. Ager; Mark A. Finney


    Wildfire simulation models are being widely used by fire and fuels specialists in the U.S. to support tactical and strategic decisions related to the mitigation of wildfire risk. Much of this application has resulted from the development of a minimum travel time (MTT) fire spread algorithm (M. Finney) that makes it computationally feasible to simulate thousands of...

  9. Hydraulic modeling development and application in water resources engineering (United States)

    Simoes, Francisco J.; Yang, Chih Ted; Wang, Lawrence K.


    The use of modeling has become widespread in water resources engineering and science to study rivers, lakes, estuaries, and coastal regions. For example, computer models are commonly used to forecast anthropogenic effects on the environment, and to help provide advanced mitigation measures against catastrophic events such as natural and dam-break floods. Linking hydraulic models to vegetation and habitat models has expanded their use in multidisciplinary applications to the riparian corridor. Implementation of these models in software packages on personal desktop computers has made them accessible to the general engineering community, and their use has been popularized by the need of minimal training due to intuitive graphical user interface front ends. Models are, however, complex and nontrivial, to the extent that even common terminology is sometimes ambiguous and often applied incorrectly. In fact, many efforts are currently under way in order to standardize terminology and offer guidelines for good practice, but none has yet reached unanimous acceptance. This chapter provides a view of the elements involved in modeling surface flows for the application in environmental water resources engineering. It presents the concepts and steps necessary for rational model development and use by starting with the exploration of the ideas involved in defining a model. Tangible form of those ideas is provided by the development of a mathematical and corresponding numerical hydraulic model, which is given with a substantial amount of detail. The issues of model deployment in a practical and productive work environment are also addressed. The chapter ends by presenting a few model applications highlighting the need for good quality control in model validation.

  10. Fault mechanism analysis and simulation for continuity resistance test of electrical components in aircraft engine (United States)

    Shi, Xudong; Yin, Yaping; Wang, Jialin; Sun, Zhaorong


    A large number of electrical components are used in civil aircraft engines, whose electrical circuits are usually intricate and complicated. Continuity resistance is an important parameter for the operating state of electrical components. Electrical continuity fault has serious impact on the reliability of the aircraft engine. In this paper, mathematical models of electrical components are established, and simulation is made by Simulink to analyze the electrical continuity fault.

  11. Development of biosensors and their application in metabolic engineering

    DEFF Research Database (Denmark)

    Zhang, Jie; Jensen, Michael Krogh; Keasling, Jay


    for the desired phenotypes. However, methods available for microbial genome diversification far exceed our ability to screen and select for those variants with optimal performance. Genetically encoded biosensors have shown the potential to address this gap, given their ability to respond to small molecule binding...... and ease of implementation with high-throughput analysis. Here we describe recent progress in biosensor development and their applications in a metabolic engineering context. We also highlight examples of how biosensors can be integrated with synthetic circuits to exert feedback regulation...


    Directory of Open Access Journals (Sweden)



    Full Text Available This paper is areview of last10years research papersrelatedto the Bayesiannetworks (BNapplication in power systems engineering (PSE. The various uses of BN in the PSE have been classified according to: forecasting, reliability, stability, defects, steady stateestimation, other. The paper is structured in three parts followed by conclusions. The first part introduces the purpose of the paper, the second part presents the concept of BN, the third part deals with application of BN in the PSE, the paper finalizing with the conclusions.

  13. Validation of a zero-dimensional and 2-phase combustion model for dual-fuel compression ignition engine simulation

    Directory of Open Access Journals (Sweden)

    Mikulski Maciej


    Full Text Available Increasing demands for the reduction of exhaust emissions and the pursuit to re-duce the use of fossil fuels require the search for new fuelling technologies in combustion engines. One of the most promising technologies is the multi-fuel compression ignition engine concept, in which a small dose of liquid fuel injected directly into the cylinder acts as the ignition inhibitor of the gaseous fuel. Achieving the optimum combustion process in such an engine requires the application of advanced control algorithms which require mathematical modelling support. In response to the growing demand for new simulation tools, a 0-D model of a dual-fuel engine was proposed and validated. The validation was performed in a broad range of engine operating points, including various speeds and load condition, as well as different natural gas/diesel blend ratios. It was demonstrated that the average model calculation error within the entire cycle did not exceed 6.2%, and was comparable to the measurement results cycle to cycle variations. The maximum model calculation error in a single point of a cycle was 15% for one of the complex (multipoint injection cases. In other cases, it did not exceed 11%.

  14. Engine simulation models for the cycles of BE1 and report on obtained performance data: Model development with the Gas turbine Simulation Program (GSP)

    NARCIS (Netherlands)

    Visser, W.P.J.; Head, A.J.


    report describes the work conducted by TUD for WP 1.3.3 of the ESPOSA project for the development of the BE1 engine simulation model in NLR’s Gas turbine Simulation Program, GSP. Results include simulation results, validation and the GSP model project files. The model is based on simulated data from

  15. 48 CFR 836.606-73 - Application of 6 percent architect-engineer fee limitation. (United States)


    ... architect-engineer fee limitation. 836.606-73 Section 836.606-73 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS SPECIAL CATEGORIES OF CONTRACTING CONSTRUCTION AND ARCHITECT-ENGINEER CONTRACTS Architect-Engineer Services 836.606-73 Application of 6 percent architect-engineer fee limitation...

  16. Material properties in unconfined compression of gelatin hydrogel for skin tissue engineering applications. (United States)

    Karimi, Alireza; Navidbakhsh, Mahdi


    Gelatin (Gel) has been reported as a promising candidate in tissue engineering owing to its easy availability, biocompatibility, and biodegradability. Gel hydrogel is of potential to be cross-linked with different materials to enhance their biocompatibility for cell culture for tissue engineering applications. The mechanical properties of this versatile material, however, have not been thoroughly determined. In this study, the linear elastic (Young's modulus and maximum stress) and non-linear hyperelastic (hyperelastic coefficients) mechanical properties of prepared hydrogels at different contents of Gel (wt%) were measured, and its Young's modulus was compared with that of skin tissue. The prepared cylindrical Gel hydrogels were subjected to a series of unconfined compression tests. The hyperelastic strain energy density function was calibrated using the compressive experimental data. The potential ability of the Yeoh hyperelastic constitutive equation, which has been proposed as the best material model to represent the non-linear behavior of hydrogels, was verified using finite element (FE) simulations. The results revealed that the Young's modulus and maximum stress of hydrogels are increased by the addition of Gel. The highest Young's modulus (81 kPa) and maximum stress (24 kPa) were observed for hydrogels with 15 wt% Gel. Results also showed that the hydrogels with a relatively lower content (7.5 wt%) for skin tissue engineering. The Yeoh material model was closely fitted with the experimental data and could be used in further biomechanical simulations of the hydrogels. The experimental results were also compared well with those predicted by the FE models. The results of this study might have implications not only for the understanding of the mechanical properties of Gel hydrogel but also for the fabrication of polymeric substrate materials suitable for skin tissue engineering applications.

  17. Multiple-cycle Simulation of a Pulse Detonation Engine Ejector (United States)

    Yungster, S.; Perkins, H. D.


    This paper presents the results of a study involving single and multiple-cycle numerical simulations of various PDE-ejector configurations utilizing hydrogen-oxygen mixtures. The objective was to investigate the thrust, impulse and mass flow rate characteristics of these devices. The results indicate that ejector systems can utilize the energy stored in the strong shock wave exiting the detonation tube to augment the impulse obtained from the detonation tube alone. Impulse augmentation ratios of up to 1.9 were achieved. The axial location of the converging-diverging ejectors relative to the end of the detonation tube were shown to affect the performance of the system.

  18. Calibration and Forward Uncertainty Propagation for Large-eddy Simulations of Engineering Flows

    Energy Technology Data Exchange (ETDEWEB)

    Templeton, Jeremy Alan [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Blaylock, Myra L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Domino, Stefan P. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Hewson, John C. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kumar, Pritvi Raj [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ling, Julia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Najm, Habib N. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Ruiz, Anthony [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Safta, Cosmin [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Sargsyan, Khachik [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Stewart, Alessia [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Wagner, Gregory [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)


    The objective of this work is to investigate the efficacy of using calibration strategies from Uncertainty Quantification (UQ) to determine model coefficients for LES. As the target methods are for engineering LES, uncertainty from numerical aspects of the model must also be quantified. 15 The ultimate goal of this research thread is to generate a cost versus accuracy curve for LES such that the cost could be minimized given an accuracy prescribed by an engineering need. Realization of this goal would enable LES to serve as a predictive simulation tool within the engineering design process.

  19. Modeling and simulation in the systems engineering life cycle core concepts and accompanying lectures

    CERN Document Server

    Loper, Margaret L


    This easy to read text/reference provides a broad introduction to the fundamental concepts of modeling and simulation (M&S) and systems engineering, highlighting how M&S is used across the entire systems engineering lifecycle. Each chapter corresponds to a short lecture covering a core topic in M&S or systems engineering.  Topics and features: reviews the full breadth of technologies, methodologies and uses of M&S, rather than just focusing on a specific aspect of the field; presents contributions from renowned specialists in each topic covered; introduces the foundational elements and proce

  20. Applications of chaos and nonlinear dynamics in science and engineering

    CERN Document Server

    Rondoni, Lamberto; Mitra, Mala

    Chaos and nonlinear dynamics initially developed as a new emergent field with its foundation in physics and applied mathematics. The highly generic, interdisciplinary quality of the insights gained in the last few decades has spawned myriad applications in almost all branches of science and technology—and even well beyond. Wherever the quantitative modeling and analysis of complex, nonlinear phenomena are required, chaos theory and its methods can play a key role.    This second volume concentrates on reviewing further relevant, contemporary applications of chaotic nonlinear systems as they apply to the various cutting-edge branches of engineering. This encompasses, but is not limited to, topics such as the spread of epidemics; electronic circuits; chaos control in mechanical devices; secure communication; and digital watermarking. Featuring contributions from active and leading research groups, this collection is ideal both as a reference work and as a ‘recipe book’ full of tried and tested, successf...

  1. Continuous nonlinear optimization for engineering applications in GAMS technology

    CERN Document Server

    Andrei, Neculai


    This book presents the theoretical details and computational performances of algorithms used for solving continuous nonlinear optimization applications imbedded in GAMS. Aimed toward scientists and graduate students who utilize optimization methods to model and solve problems in mathematical programming, operations research, business, engineering, and industry, this book enables readers with a background in nonlinear optimization and linear algebra to use GAMS technology to understand and utilize its important capabilities to optimize algorithms for modeling and solving complex, large-scale, continuous nonlinear optimization problems or applications. Beginning with an overview of constrained nonlinear optimization methods, this book moves on to illustrate key aspects of mathematical modeling through modeling technologies based on algebraically oriented modeling languages. Next, the main feature of GAMS, an algebraically oriented language that allows for high-level algebraic representation of mathematical opti...

  2. Surface Engineering of Graphene-Based Nanomaterials for Biomedical Applications (United States)


    Graphene-based nanomaterials have attracted tremendous interest over the past decade due to their unique electronic, optical, mechanical, and chemical properties. However, the biomedical applications of these intriguing nanomaterials are still limited due to their suboptimal solubility/biocompatibility, potential toxicity, and difficulties in achieving active tumor targeting, just to name a few. In this Topical Review, we will discuss in detail the important role of surface engineering (i.e., bioconjugation) in improving the in vitro/in vivo stability and enriching the functionality of graphene-based nanomaterials, which can enable single/multimodality imaging (e.g., optical imaging, positron emission tomography, magnetic resonance imaging) and therapy (e.g., photothermal therapy, photodynamic therapy, and drug/gene delivery) of cancer. Current challenges and future research directions are also discussed and we believe that graphene-based nanomaterials are attractive nanoplatforms for a broad array of future biomedical applications. PMID:25117569

  3. Basic Potential of Carbon Nanotubes in Tissue Engineering Applications

    Directory of Open Access Journals (Sweden)

    Hisao Haniu


    Full Text Available Carbon nanotubes (CNTs are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.

  4. Molecularly engineered graphene surfaces for sensing applications: A review

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Jingquan, E-mail: [College of Chemical Science and Engineering, Laboratory of Fiber Materials and Modern Textile, The Growing Base for State Key Laboratory, Qingdao University, Qingdao (China); Liu, Zhen; Barrow, Colin J. [Centre for Chemistry and Biotechnology, Deakin University, Geelong, VIC 3217 (Australia); Yang, Wenrong, E-mail: [Centre for Chemistry and Biotechnology, Deakin University, Geelong, VIC 3217 (Australia)


    Highlights: • The importance of surface chemistry of graphene materials is clearly described. • We discuss molecularly engineered graphene surfaces for sensing applications. • We describe the latest developments of these materials for sensing technology. - Abstract: Graphene is scientifically and commercially important because of its unique molecular structure which is monoatomic in thickness, rigorously two-dimensional and highly conjugated. Consequently, graphene exhibits exceptional electrical, optical, thermal and mechanical properties. Herein, we critically discuss the surface modification of graphene, the specific advantages that graphene-based materials can provide over other materials in sensor research and their related chemical and electrochemical properties. Furthermore, we describe the latest developments in the use of these materials for sensing technology, including chemical sensors and biosensors and their applications in security, environmental safety and diseases detection and diagnosis.

  5. UE4Sim: A Photo-Realistic Simulator for Computer Vision Applications

    KAUST Repository

    Mueller, Matthias


    We present a photo-realistic training and evaluation simulator (UE4Sim) with extensive applications across various fields of computer vision. Built on top of the Unreal Engine, the simulator integrates full featured physics based cars, unmanned aerial vehicles (UAVs), and animated human actors in diverse urban and suburban 3D environments. We demonstrate the versatility of the simulator with two case studies: autonomous UAV-based tracking of moving objects and autonomous driving using supervised learning. The simulator fully integrates both several state-of-the-art tracking algorithms with a benchmark evaluation tool and a deep neural network (DNN) architecture for training vehicles to drive autonomously. It generates synthetic photo-realistic datasets with automatic ground truth annotations to easily extend existing real-world datasets and provides extensive synthetic data variety through its ability to reconfigure synthetic worlds on the fly using an automatic world generation tool.

  6. Virtual Environment Computer Simulations to Support Human Factors Engineering and Operations Analysis for the RLV Program (United States)

    Lunsford, Myrtis Leigh


    The Army-NASA Virtual Innovations Laboratory (ANVIL) was recently created to provide virtual reality tools for performing Human Engineering and operations analysis for both NASA and the Army. The author's summer research project consisted of developing and refining these tools for NASA's Reusable Launch Vehicle (RLV) program. Several general simulations were developed for use by the ANVIL for the evaluation of the X34 Engine Changeout procedure. These simulations were developed with the software tool dVISE 4.0.0 produced by Division Inc. All software was run on an SGI Indigo2 High Impact. This paper describes the simulations, various problems encountered with the simulations, other summer activities, and possible work for the future. We first begin with a brief description of virtual reality systems.

  7. Simulation models generator. Applications in scheduling

    Directory of Open Access Journals (Sweden)

    Omar Danilo Castrillón


    Rev.Mate.Teor.Aplic. (ISSN 1409-2433 Vol. 20(2: 231–241, July 2013 generador de modelos de simulacion 233 will, in order to have an approach to reality to evaluate decisions in order to take more assertive. To test prototype was used as the modeling example of a production system with 9 machines and 5 works as a job shop configuration, testing stops processing times and stochastic machine to measure rates of use of machines and time average jobs in the system, as measures of system performance. This test shows the goodness of the prototype, to save the user the simulation model building

  8. 3D bioprinting and the current applications in tissue engineering. (United States)

    Huang, Ying; Zhang, Xiao-Fei; Gao, Guifang; Yonezawa, Tomo; Cui, Xiaofeng


    Bioprinting as an enabling technology for tissue engineering possesses the promises to fabricate highly mimicked tissue or organs with digital control. As one of the biofabrication approaches, bioprinting has the advantages of high throughput and precise control of both scaffold and cells. Therefore, this technology is not only ideal for translational medicine but also for basic research applications. Bioprinting has already been widely applied to construct functional tissues such as vasculature, muscle, cartilage, and bone. In this review, the authors introduce the most popular techniques currently applied in bioprinting, as well as the various bioprinting processes. In addition, the composition of bioink including scaffolds and cells are described. Furthermore, the most current applications in organ and tissue bioprinting are introduced. The authors also discuss the challenges we are currently facing and the great potential of bioprinting. This technology has the capacity not only in complex tissue structure fabrication based on the converted medical images, but also as an efficient tool for drug discovery and preclinical testing. One of the most promising future advances of bioprinting is to develop a standard medical device with the capacity of treating patients directly on the repairing site, which requires the development of automation and robotic technology, as well as our further understanding of biomaterials and stem cell biology to integrate various printing mechanisms for multi-phasic tissue engineering. Copyright © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  9. Strategies in biomimetic surface engineering of nanoparticles for biomedical applications (United States)

    Gong, Yong-Kuan; Winnik, Françoise M.


    Engineered nanoparticles (NPs) play an increasingly important role in biomedical sciences and in nanomedicine. Yet, in spite of significant advances, it remains difficult to construct drug-loaded NPs with precisely defined therapeutic effects, in terms of release time and spatial targeting. The body is a highly complex system that imposes multiple physiological and cellular barriers to foreign objects. Upon injection in the blood stream or following oral administation, NPs have to bypass numerous barriers prior to reaching their intended target. A particularly successful design strategy consists in masking the NP to the biological environment by covering it with an outer surface mimicking the composition and functionality of the cell's external membrane. This review describes this biomimetic approach. First, we outline key features of the composition and function of the cell membrane. Then, we present recent developments in the fabrication of molecules that mimic biomolecules present on the cell membrane, such as proteins, peptides, and carbohydrates. We present effective strategies to link such bioactive molecules to the NPs surface and we highlight the power of this approach by presenting some exciting examples of biomimetically engineered NPs useful for multimodal diagnostics and for target-specific drug/gene delivery applications. Finally, critical directions for future research and applications of biomimetic NPs are suggested to the readers.

  10. The application of electrospinning used in meniscus tissue engineering. (United States)

    Chen, Mingxue; Gao, Shuang; Wang, Pei; Li, Yan; Guo, Weimin; Zhang, Yu; Wang, Mingjie; Xiao, Tongguang; Zhang, Zengzeng; Zhang, Xueliang; Jing, Xiaoguang; Li, Xu; Liu, Shuyun; Guo, Quanyi; Xi, Tingfei


    Meniscus is a fibrocartilaginous organ to redistribute stress and enhance the stability of knee joint. Meniscus injury is common and still a formidable challenge to orthopedic surgeons. Surgical techniques and allograft transplantation were primary approaches to meniscus repair, but with intrinsic limitations in clinical practice. Tissue engineering is the most promising method to repair meniscus at present. Electrospinning is a method to fabricate fibers in small scale. With different materials and parameters, electrospinning materials could have different mechanical properties, porosity, and orientation, which could mimic architectural features and mechanical properties of native meniscus. Therefore, electrospinning materials could be used in meniscus regeneration and curing. This review gave a brief introduction of meniscus structure, injury, treatment and the application of electrospinning fibers in meniscus tissue engineering and curing. Besides that, we summarized materials commonly used in electrospinning to fabricate meniscus scaffolds, and discussed the form of electrospinning fibers used such as scaffold, substitute and patch. Finally, the function of electrospinning fibers, for example, carrying drugs, providing mechanical properties were described. The potential applications of electrospinning fibers in meniscus therapy were proposed.

  11. Engineering Thermostable Microbial Xylanases Toward its Industrial Applications. (United States)

    Kumar, Vishal; Dangi, Arun Kumar; Shukla, Pratyoosh


    Xylanases are one of the important hydrolytic enzymes which hydrolyze the β-1, 4 xylosidic linkage of the backbone of the xylan polymeric chain which consists of xylose subunits. Xylanases are mainly found in plant cell walls and are produced by several kinds of microorganisms such as fungi, bacteria, yeast, and some protozoans. The fungi are considered as most potent xylanase producers than that of yeast and bacteria. There is a broad series of industrial applications for the thermostable xylanase as an industrial enzyme. Thermostable xylanases have been used in a number of industries such as paper and pulp industry, biofuel industry, food and feed industry, textile industry, etc. The present review explores xylanase-substrate interactions using gene-editing tools toward the comprehension in improvement in industrial stability of xylanases. The various protein-engineering and metabolic-engineering methods have also been explored to improve operational stability of xylanase. Thermostable xylanases have also been used for improvement in animal feed nutritional value. Furthermore, they have been used directly in bakery and breweries, including a major use in paper and pulp industry as a biobleaching agent. This present review envisages some of such applications of thermostable xylanases for their bioengineering.

  12. Magnesium incorporated chitosan based scaffolds for tissue engineering applications

    Directory of Open Access Journals (Sweden)

    Udhab Adhikari


    Full Text Available Chitosan based porous scaffolds are of great interest in biomedical applications especially in tissue engineering because of their excellent biocompatibility in vivo, controllable degradation rate and tailorable mechanical properties. This paper presents a study of the fabrication and characterization of bioactive scaffolds made of chitosan (CS, carboxymethyl chitosan (CMC and magnesium gluconate (MgG. Scaffolds were fabricated by subsequent freezing-induced phase separation and lyophilization of polyelectrolyte complexes of CS, CMC and MgG. The scaffolds possess uniform porosity with highly interconnected pores of 50–250 μm size range. Compressive strengths up to 400 kPa, and elastic moduli up to 5 MPa were obtained. The scaffolds were found to remain intact, retaining their original three-dimensional frameworks while testing in in-vitro conditions. These scaffolds exhibited no cytotoxicity to 3T3 fibroblast and osteoblast cells. These observations demonstrate the efficacy of this new approach to preparing scaffold materials suitable for tissue engineering applications.

  13. Development of a Twin-Spool Turbofan Engine Simulation Using the Toolbox for the Modeling and Analysis of Thermodynamic Systems (T-MATS) (United States)

    Zinnecker, Alicia M.; Chapman, Jeffryes W.; Lavelle, Thomas M.; Litt, Jonathan S.


    The Toolbox for the Modeling and Analysis of Thermodynamic Systems (T-MATS) is a tool that has been developed to allow a user to build custom models of systems governed by thermodynamic principles using a template to model each basic process. Validation of this tool in an engine model application was performed through reconstruction of the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) (v2) using the building blocks from the T-MATS (v1) library. In order to match the two engine models, it was necessary to address differences in several assumptions made in the two modeling approaches. After these modifications were made, validation of the engine model continued by integrating both a steady-state and dynamic iterative solver with the engine plant and comparing results from steady-state and transient simulation of the T-MATS and C-MAPSS models. The results show that the T-MATS engine model was accurate within 3% of the C-MAPSS model, with inaccuracy attributed to the increased dimension of the iterative solver solution space required by the engine model constructed using the T-MATS library. This demonstrates that, given an understanding of the modeling assumptions made in T-MATS and a baseline model, the T-MATS tool provides a viable option for constructing a computational model of a twin-spool turbofan engine that may be used in simulation studies.

  14. Development of a Twin-spool Turbofan Engine Simulation Using the Toolbox for Modeling and Analysis of Thermodynamic Systems (T-MATS) (United States)

    Zinnecker, Alicia M.; Chapman, Jeffryes W.; Lavelle, Thomas M.; Litt, Johathan S.


    The Toolbox for Modeling and Analysis of Thermodynamic Systems (T-MATS) is a tool that has been developed to allow a user to build custom models of systems governed by thermodynamic principles using a template to model each basic process. Validation of this tool in an engine model application was performed through reconstruction of the Commercial Modular Aero-Propulsion System Simulation (C-MAPSS) (v2) using the building blocks from the T-MATS (v1) library. In order to match the two engine models, it was necessary to address differences in several assumptions made in the two modeling approaches. After these modifications were made, validation of the engine model continued by integrating both a steady-state and dynamic iterative solver with the engine plant and comparing results from steady-state and transient simulation of the T-MATS and C-MAPSS models. The results show that the T-MATS engine model was accurate within 3 of the C-MAPSS model, with inaccuracy attributed to the increased dimension of the iterative solver solution space required by the engine model constructed using the T-MATS library. This demonstrates that, given an understanding of the modeling assumptions made in T-MATS and a baseline model, the T-MATS tool provides a viable option for constructing a computational model of a twin-spool turbofan engine that may be used in simulation studies.

  15. Synergetic approachto simulation of physical wear of engineering technical systems

    Directory of Open Access Journals (Sweden)

    Kirillov Andrey Mikhaylovich


    Full Text Available In course of time in structural elements of engineering technical systems defects and damages are accumulated, which is caused by loadings and environmental influence. The defects are any inconsistencies with normative documents, and damages are discontinuances of structure. The defects and damages lead to decrease of operational properties of structures (their bearing capacity, waterproofing, thermal resistance, etc. The occurrences of such character are called physical wear.In the article the authors show the possibility of phase trajectory use of the processes of physical wear, creep and cusp catastrophe for determinating the critical timepoint, corresponding to the beginning of the system damage catastrophic growth. The alternative approach to the description of the processes of physical wear and creep of pavement consisting in comparison of asphalt concrete creep curve and the curve of the mathematical model of cusp catastrophe, is received. The applied synergetic approach gives us the chance to improve the existing and create new methods of pavement resource forecasting and assessment of physical wear of any technical constructions.

  16. Rocket-Plume Spectroscopy Simulation for Hydrocarbon-Fueled Rocket Engines (United States)

    Tejwani, Gopal D.


    The UV-Vis spectroscopic system for plume diagnostics monitors rocket engine health by using several analytical tools developed at Stennis Space Center (SSC), including the rocket plume spectroscopy simulation code (RPSSC), to identify and quantify the alloys from the metallic elements observed in engine plumes. Because the hydrocarbon-fueled rocket engine is likely to contain C2, CO, CH, CN, and NO in addition to OH and H2O, the relevant electronic bands of these molecules in the spectral range of 300 to 850 nm in the RPSSC have been included. SSC incorporated several enhancements and modifications to the original line-by-line spectral simulation computer program implemented for plume spectral data analysis and quantification in 1994. These changes made the program applicable to the Space Shuttle Main Engine (SSME) and the Diagnostic Testbed Facility Thruster (DTFT) exhaust plume spectral data. Modifications included updating the molecular and spectral parameters for OH, adding spectral parameter input files optimized for the 10 elements of interest in the spectral range from 320 to 430 nm and linking the output to graphing and analysis packages. Additionally, the ability to handle the non-uniform wavelength interval at which the spectral computations are made was added. This allowed a precise superposition of wavelengths at which the spectral measurements have been made with the wavelengths at which the spectral computations are done by using the line-by-line (LBL) code. To account for hydrocarbon combustion products in the plume, which might interfere with detection and quantification of metallic elements in the spectral region of 300 to 850 nm, the spectroscopic code has been enhanced to include the carbon-based combustion species of C2, CO, and CH. In addition, CN and NO have spectral bands in 300 to 850 nm and, while these molecules are not direct products of hydrocarbon-oxygen combustion systems, they can show up if nitrogen or a nitrogen compound is present



    Nureddin Dinler; Nuri Yucel


    Combustion is an important subject of internal combustion engine studies. To reduce the air pollution from internal combustion engines and to increase the engine performance, it is required to increase combustion efficiency. In this study, effects of air/fuel ratio were investigated numerically. An axisymmetrical internal combustion engine was modeled in order to simulate in-cylinder engine flow and combustion. Two dimensional transient continuity, momentum, turbulence, energy, and combustion...

  18. Reaction engineering simulations of oxidative coupling of methane in a circulating fluidized-bed reactor

    Energy Technology Data Exchange (ETDEWEB)

    Pannek, U.; Mleczko, L. [Bochum Univ. (Germany). Lehrstuhl fuer Technische Chemie


    Oxidative coupling of methane in a circulating fluidized-bed reactor was investigated by means of reaction engineering modeling and simulations. A model of the reactor that combines comprehensive kinetics of the OCM and a model for the description of the bed hydrodynamics was developed and applied to predict the reactor performance. The important goal of the simulations was a better understanding of the effect of the hydrodynamic conditions in the riser reactor on the reaction pathway and the product distribution. (orig.)

  19. Multigrid methods with applications to reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Xiao, Shengyou [Univ. of Texas, Austin, TX (United States)


    Multigrid methods are studied for solving elliptic partial differential equations. Focus is on parallel multigrid methods and their use for reservoir simulation. Multicolor Fourier analysis is used to analyze the behavior of standard multigrid methods for problems in one and two dimensions. Relation between multicolor and standard Fourier analysis is established. Multiple coarse grid methods for solving model problems in 1 and 2 dimensions are considered; at each coarse grid level we use more than one coarse grid to improve convergence. For a given Dirichlet problem, a related extended problem is first constructed; a purification procedure can be used to obtain Moore-Penrose solutions of the singular systems encountered. For solving anisotropic equations, semicoarsening and line smoothing techniques are used with multiple coarse grid methods to improve convergence. Two-level convergence factors are estimated using multicolor. In the case where each operator has the same stencil on each grid point on one level, exact multilevel convergence factors can be obtained. For solving partial differential equations with discontinuous coefficients, interpolation and restriction operators should include information about the equation coefficients. Matrix-dependent interpolation and restriction operators based on the Schur complement can be used in nonsymmetric cases. A semicoarsening multigrid solver with these operators is used in UTCOMP, a 3-D, multiphase, multicomponent, compositional reservoir simulator. The numerical experiments are carried out on different computing systems. Results indicate that the multigrid methods are promising.

  20. Minimizing the Discrepancy between Simulated and Historical Failures in Turbine Engines: A Simulation-Based Optimization Method

    Directory of Open Access Journals (Sweden)

    Ahmed Kibria


    Full Text Available The reliability modeling of a module in a turbine engine requires knowledge of its failure rate, which can be estimated by identifying statistical distributions describing the percentage of failure per component within the turbine module. The correct definition of the failure statistical behavior per component is highly dependent on the engineer skills and may present significant discrepancies with respect to the historical data. There is no formal methodology to approach this problem and a large number of labor hours are spent trying to reduce the discrepancy by manually adjusting the distribution’s parameters. This paper addresses this problem and provides a simulation-based optimization method for the minimization of the discrepancy between the simulated and the historical percentage of failures for turbine engine components. The proposed methodology optimizes the parameter values of the component’s failure statistical distributions within the component’s likelihood confidence bounds. A complete testing of the proposed method is performed on a turbine engine case study. The method can be considered as a decision-making tool for maintenance, repair, and overhaul companies and will potentially reduce the cost of labor associated to finding the appropriate value of the distribution parameters for each component/failure mode in the model and increase the accuracy in the prediction of the mean time to failures (MTTF.

  1. Online frequency estimation with applications to engine and generator sets (United States)

    Manngård, Mikael; Böling, Jari M.


    Frequency and spectral analysis based on the discrete Fourier transform is a fundamental task in signal processing and machine diagnostics. This paper aims at presenting computationally efficient methods for real-time estimation of stationary and time-varying frequency components in signals. A brief survey of the sliding time window discrete Fourier transform and Goertzel filter is presented, and two filter banks consisting of: (i) sliding time window Goertzel filters (ii) infinite impulse response narrow bandpass filters are proposed for estimating instantaneous frequencies. The proposed methods show excellent results on both simulation studies and on a case study using angular speed data measurements of the crankshaft of a marine diesel engine-generator set.

  2. Update: Advancement of Contact Dynamics Modeling for Human Spaceflight Simulation Applications (United States)

    Brain, Thomas A.; Kovel, Erik B.; MacLean, John R.; Quiocho, Leslie J.


    Pong is a new software tool developed at the NASA Johnson Space Center that advances interference-based geometric contact dynamics based on 3D graphics models. The Pong software consists of three parts: a set of scripts to extract geometric data from 3D graphics models, a contact dynamics engine that provides collision detection and force calculations based on the extracted geometric data, and a set of scripts for visualizing the dynamics response with the 3D graphics models. The contact dynamics engine can be linked with an external multibody dynamics engine to provide an integrated multibody contact dynamics simulation. This paper provides a detailed overview of Pong including the overall approach and modeling capabilities, which encompasses force generation from contact primitives and friction to computational performance. Two specific Pong-based examples of International Space Station applications are discussed, and the related verification and validation using this new tool are also addressed.

  3. Securing Sensitive Flight and Engine Simulation Data Using Smart Card Technology (United States)

    Blaser, Tammy M.


    NASA Glenn Research Center has developed a smart card prototype capable of encrypting and decrypting disk files required to run a distributed aerospace propulsion simulation. Triple Data Encryption Standard (3DES) encryption is used to secure the sensitive intellectual property on disk pre, during, and post simulation execution. The prototype operates as a secure system and maintains its authorized state by safely storing and permanently retaining the encryption keys only on the smart card. The prototype is capable of authenticating a single smart card user and includes pre simulation and post simulation tools for analysis and training purposes. The prototype's design is highly generic and can be used to protect any sensitive disk files with growth capability to urn multiple simulations. The NASA computer engineer developed the prototype on an interoperable programming environment to enable porting to other Numerical Propulsion System Simulation (NPSS) capable operating system environments.

  4. New Tools Being Developed for Engine- Airframe Blade-Out Structural Simulations (United States)

    Lawrence, Charles


    One of the primary concerns of aircraft structure designers is the accurate simulation of the blade-out event. This is required for the aircraft to pass Federal Aviation Administration (FAA) certification and to ensure that the aircraft is safe for operation. Typically, the most severe blade-out occurs when a first-stage fan blade in a high-bypass gas turbine engine is released. Structural loading results from both the impact of the blade onto the containment ring and the subsequent instantaneous unbalance of the rotating components. Reliable simulations of blade-out are required to ensure structural integrity during flight as well as to guarantee successful blade-out certification testing. The loads generated by these analyses are critical to the design teams for several components of the airplane structures including the engine, nacelle, strut, and wing, as well as the aircraft fuselage. Currently, a collection of simulation tools is used for aircraft structural design. Detailed high-fidelity simulation tools are used to capture the structural loads resulting from blade loss, and then these loads are used as input into an overall system model that includes complete structural models of both the engines and the airframe. The detailed simulation (shown in the figure) includes the time-dependent trajectory of the lost blade and its interactions with the containment structure, and the system simulation includes the lost blade loadings and the interactions between the rotating turbomachinery and the remaining aircraft structural components. General-purpose finite element structural analysis codes are typically used, and special provisions are made to include transient effects from the blade loss and rotational effects resulting from the engine s turbomachinery. To develop and validate these new tools with test data, the NASA Glenn Research Center has teamed with GE Aircraft Engines, Pratt & Whitney, Boeing Commercial Aircraft, Rolls-Royce, and MSC.Software.

  5. Simulations

    CERN Document Server

    Ngada, Narcisse


    The complexity and cost of building and running high-power electrical systems make the use of simulations unavoidable. The simulations available today provide great understanding about how systems really operate. This paper helps the reader to gain an insight into simulation in the field of power converters for particle accelerators. Starting with the definition and basic principles of simulation, two simulation types, as well as their leading tools, are presented: analog and numerical simulations. Some practical applications of each simulation type are also considered. The final conclusion then summarizes the main important items to keep in mind before opting for a simulation tool or before performing a simulation.

  6. CAD/CAM/CAI Application for High-Precision Machining of Internal Combustion Engine Pistons

    Directory of Open Access Journals (Sweden)

    V. V. Postnov


    Full Text Available CAD/CAM/CAI application solutions for internal combustion engine pistons machining was analyzed. Low-volume technology of internal combustion engine pistons production was proposed. Fixture for CNC turning center was designed.

  7. How to Identify Possible Applications of Product Configuration Systems in Engineer-to-Order Companies

    DEFF Research Database (Denmark)

    Kristjansdottir, Katrin; Shafiee, Sara; Hvam, Lars


    Product configuration systems (PCS) play an essential role when providing customised and engineered products efficiently. Literature in the field describes numerous strategies to develop PCS but neglects to identify different application areas. This topic is particularly important for engineer...

  8. Analysis of experimental hydrogen engine data and hydrogen vehicle performance and emissions simulation

    Energy Technology Data Exchange (ETDEWEB)

    Aceves, S.M.


    This paper reports the engine and vehicle simulation and analysis done at Lawrence Livermore (LLNL) as a part of a joint optimized hydrogen engine development effort. Project participants are: Sandia National Laboratory, California (SNLC), responsible for experimental evaluation; Los Alamos National Laboratory (LANL), responsible for detailed fluid mechanics engine evaluations, and the University of Miami, responsible for engine friction reduction. Fuel cells are considered as the ideal power source for future vehicles, due to their high efficiency and low emissions. However, extensive use of fuel cells in light-duty vehicles is likely to be years away, due to their high manufacturing cost. Hydrogen-fueled, spark-ignited, homogeneous-charge engines offer a near-term alternative to fuel cells. Hydrogen in a spark-ignited engine can be burned at very low equivalence ratios, so that NO{sub x} emissions can be reduced to less than 10 ppm without catalyst. HC and CO emissions may result from oxidation of engine oil, but by proper design are negligible (a few ppm). Lean operation also results in increased indicated efficiency due to the thermodynamic properties of the gaseous mixture contained in the cylinder. The high effective octane number of hydrogen allows the use of a high compression ratio, further increasing engine efficiency.

  9. Design, development, and evaluation of a second generation interactive Simulator for Engineering Ethics Education (SEEE2). (United States)

    Alfred, Michael; Chung, Christopher A


    This paper describes a second generation Simulator for Engineering Ethics Education. Details describing the first generation activities of this overall effort are published in Chung and Alfred (Sci Eng Ethics 15:189-199, 2009). The second generation research effort represents a major development in the interactive simulator educational approach. As with the first generation effort, the simulator places students in first person perspective scenarios involving different types of ethical situations. Students must still gather data, assess the situation, and make decisions. The approach still requires students to develop their own ability to identify and respond to ethical engineering situations. However, were as, the generation one effort involved the use of a dogmatic model based on National Society of Professional Engineers' Code of Ethics, the new generation two model is based on a mathematical model of the actual experiences of engineers involved in ethical situations. This approach also allows the use of feedback in the form of decision effectiveness and professional career impact. Statistical comparisons indicate a 59 percent increase in overall knowledge and a 19 percent improvement in teaching effectiveness over an Internet Engineering Ethics resource based approach.

  10. Extending the Capabilities of Closed-loop Distributed Engine Control Simulations Using LAN Communication (United States)

    Aretskin-Hariton, Eliot D.; Zinnecker, Alicia Mae; Culley, Dennis E.


    Distributed Engine Control (DEC) is an enabling technology that has the potential to advance the state-of-the-art in gas turbine engine control. To analyze the capabilities that DEC offers, a Hardware-In-the-Loop (HIL) test bed is being developed at NASA Glenn Research Center. This test bed will support a systems-level analysis of control capabilities in closed-loop engine simulations. The structure of the HIL emulates a virtual test cell by implementing the operator functions, control system, and engine on three separate computers. This implementation increases the flexibility and extensibility of the HIL. Here, a method is discussed for implementing these interfaces by connecting the three platforms over a dedicated Local Area Network (LAN). This approach is verified using the Commercial Modular Aero-Propulsion System Simulation 40k (C-MAPSS40k), which is typically implemented on one computer. There are marginal differences between the results from simulation of the typical and the three-computer implementation. Additional analysis of the LAN network, including characterization of network load, packet drop, and latency, is presented. The three-computer setup supports the incorporation of complex control models and proprietary engine models into the HIL framework.

  11. Analysis of experimental hydrogen engine data and hydrogen vehicle performance and emissions simulation

    Energy Technology Data Exchange (ETDEWEB)

    Aceves, S.A. [Lawrence Livermore National Lab., CA (United States)


    This paper reports the engine and vehicle simulation and analysis done at Lawrence Livermore (LLNL) as a part of a joint optimized hydrogen engine development effort. Project participants are: Sandia National Laboratory; Los Alamos National Laboratory; and the University of Miami. Fuel cells are considered as the ideal power source for future vehicles, due to their high efficiency and low emissions. However, extensive use of fuel cells in light-duty vehicles is likely to be years away, due to their high manufacturing cost. Hydrogen-fueled, spark-ignited, homogeneous-charge engines offer a near-term alternative to fuel cells. Hydrogen in a spark-ignited engine can be burned at very low equivalence ratios. NO{sub x} emissions can be reduced to less than 10 ppm without catalyst. HC and CO emissions may result from oxidation of engine oil, but by proper design are negligible (a few ppm). Lean operation also results in increased indicated efficiency due to the thermodynamic properties of the gaseous mixture contained in the cylinder. The high effective octane number of hydrogen allows the use of a high compression ratio, further increasing engine efficiency. In this paper, a simplified engine model is used for predicting hydrogen engine efficiency and emissions. The model uses basic thermodynamic equations for the compression and expansion processes, along with an empirical correlation for heat transfer, to predict engine indicated efficiency. A friction correlation and a supercharger/turbocharger model are then used to calculate brake thermal efficiency. The model is validated with many experimental points obtained in a recent evaluation of a hydrogen research engine. The experimental data are used to adjust the empirical constants in the heat release rate and heat transfer correlation. The results indicate that hydrogen lean-burn spark-ignite engines can provide Equivalent Zero Emission Vehicle (EZEV) levels in either a series hybrid or a conventional automobile.

  12. Tissue Engineering Applications of Three-Dimensional Bioprinting. (United States)

    Zhang, Xiaoying; Zhang, Yangde


    Recent advances in tissue engineering have adapted the additive manufacturing technology, also known as three-dimensional printing, which is used in several industrial applications, for the fabrication of bioscaffolds and viable tissue and/or organs to overcome the limitations of other in vitro conventional methods. 3D bioprinting technology has gained enormous attention as it enabled 3D printing of a multitude of biocompatible materials, different types of cells and other supporting growth factors into complex functional living tissues in a 3D format. A major advantage of this technology is its ability for simultaneously 3D printing various cell types in defined spatial locations, which makes this technology applicable to regenerative medicine to meet the need for suitable for transplantation suitable organs and tissues. 3D bioprinting is yet to successfully overcome the many challenges related to building 3D structures that closely resemble native organs and tissues, which are complex structures with defined microarchitecture and a variety of cell types in a confined area. An integrated approach with a combination of technologies from the fields of engineering, biomaterials science, cell biology, physics, and medicine is required to address these complexities. Meeting this challenge is being made possible by directing the 3D bioprinting to manufacture biomimetic-shaped 3D structures, using organ/tissue images, obtained from magnetic resonance imaging and computerized tomography, and employing computer-aided design and manufacturing technologies. Applications of 3D bioprinting include the generation of multilayered skin, bone, vascular grafts, heart valves, etc. The current 3D bioprinting technologies need to be improved with respect to the mechanical strength and integrity in the manufactured constructs as the presently used biomaterials are not of optimal viscosity. A better understanding of the tissue/organ microenvironment, which consists of multiple types of

  13. Introduction to computational mass transfer with applications to chemical engineering

    CERN Document Server

    Yu, Kuo-Tsung


    This book offers an easy-to-understand introduction to the computational mass transfer (CMT) method. On the basis of the contents of the first edition, this new edition is characterized by the following additional materials. It describes the successful application of this method to the simulation of the mass transfer process in a fluidized bed, as well as recent investigations and computing methods for predictions for the multi-component mass transfer process. It also demonstrates the general issues concerning computational methods for simulating the mass transfer of the rising bubble process. This new edition has been reorganized by moving the preparatory materials for Computational Fluid Dynamics (CFD) and Computational Heat Transfer into appendices, additions of new chapters, and including three new appendices on, respectively, generalized representation of the two-equation model for the CMT, derivation of the equilibrium distribution function in the lattice-Boltzmann method, and derivation of the Navier-S...

  14. Advantages and Disadvantages of Using MATLAB/ode45 for Solving Differential Equations in Engineering Applications


    Waleed K. Ahmed


    The present paper demonstrates the route used for solving differential equations for the engineering applications at UAEU. Usually students at the Engineering Requirements Unit (ERU) stage of the Faculty of Engineering at the UAEU must enroll in a course of Differential Equations and Engineering Applications (MATH 2210) as a prerequisite for the subsequent stages of their study. Mainly, one of the objectives of this course is that the students practice MATLAB software package during the cours...

  15. Driving engineering of novel antimicrobial peptides from simulations of peptide-micelle interactions

    DEFF Research Database (Denmark)

    Khandelia, Himanshu; Langham, Allison A; Kaznessis, Yiannis N


    Simulations of antimicrobial peptides in membrane mimics can provide the high resolution, atomistic picture that is necessary to decipher which sequence and structure components are responsible for activity and toxicity. With such detailed insight, engineering new sequences that are active but no...

  16. Teaching Complicated Conceptual Knowledge with Simulation Videos in Foundational Electrical Engineering Courses (United States)

    Chen, Baiyun; Wei, Lei; Li, Huihui


    Building a solid foundation of conceptual knowledge is critical for students in electrical engineering. This mixed-method case study explores the use of simulation videos to illustrate complicated conceptual knowledge in foundational communications and signal processing courses. Students found these videos to be very useful for establishing…

  17. Simulation of diesel engine emissions on the example of Fiat Panda in the NEDC test (United States)

    Botwinska, Katarzyna; Mruk, Remigiusz; Słoma, Jacek; Tucki, Karol; Zaleski, Mateusz


    Road transport may be deemed a strategic branch of modern economy. Unfortunately, a rapid increase in the number of on-road motor vehicles entails some negative consequences as well, for instance, excessive concentration of exhausts produced by engines which results in deterioration of air quality. EURO emission standards which define acceptable limits for exhaust emissions of power units is an example of an activity performed in attempt to improve air quality. The EURO standard defines permissible amount of exhausts produced by a vehicle. Presently new units are examined through NEDC test. For the purpose of this thesis, a virtual test stand in a form of a computer simulation of a chassis dynamometer was used to simulate emission of a diesel engine (compression-ignition engine) in the NEDC test. Actual parameters of the 1.3 MultiJet engine of the Fiat Panda passenger car of 2014 were applied in the model. The simulation was carried out in the Matlab Simulink environment. The simulation model of the Fiat Panda passenger car enables the designation of the emission waveform for all test stages which corresponds to the values received during an approval test in real-life conditions.

  18. Factors Affecting Perceived Learning of Engineering Students in Problem Based Learning Supported by Business Simulation (United States)

    Chaparro-Pelaez, Julian; Iglesias-Pradas, Santiago; Pascual-Miguel, Felix J.; Hernandez-Garcia, Angel


    Although literature about problem based learning (PBL) is not scarce, there is little research on experiences about learning methodologies that combine PBL and the use of simulation tools. This lack of studies is even more notable in the case of engineering courses. The motivation for this study is to show how such a combination of PBL and…

  19. Simulation of diesel engine emissions on the example of Fiat Panda in the NEDC test

    Directory of Open Access Journals (Sweden)

    Botwinska Katarzyna


    Full Text Available Road transport may be deemed a strategic branch of modern economy. Unfortunately, a rapid increase in the number of on-road motor vehicles entails some negative consequences as well, for instance, excessive concentration of exhausts produced by engines which results in deterioration of air quality. EURO emission standards which define acceptable limits for exhaust emissions of power units is an example of an activity performed in attempt to improve air quality. The EURO standard defines permissible amount of exhausts produced by a vehicle. Presently new units are examined through NEDC test. For the purpose of this thesis, a virtual test stand in a form of a computer simulation of a chassis dynamometer was used to simulate emission of a diesel engine (compression-ignition engine in the NEDC test. Actual parameters of the 1.3 MultiJet engine of the Fiat Panda passenger car of 2014 were applied in the model. The simulation was carried out in the Matlab Simulink environment. The simulation model of the Fiat Panda passenger car enables the designation of the emission waveform for all test stages which corresponds to the values received during an approval test in real-life conditions.

  20. OSCE best practice guidelines-applicability for nursing simulations. (United States)

    Kelly, Michelle A; Mitchell, Marion L; Henderson, Amanda; Jeffrey, Carol A; Groves, Michele; Nulty, Duncan D; Glover, Pauline; Knight, Sabina


    Objective structured clinical examinations (OSCEs) have been used for many years within healthcare programmes as a measure of students' and clinicians' clinical performance. OSCEs are a form of simulation and are often summative but may be formative. This educational approach requires robust design based on sound pedagogy to assure practice and assessment of holistic nursing care. As part of a project testing seven OSCE best practice guidelines (BPGs) across three sites, the BPGs were applied to an existing simulation activity. The aim of this study was to determine the applicability and value of the OSCE BPGs in an existing formative simulation. A mixed methods approach was used to address the research question: in what ways do OSCE BPGs align with simulations. The BPGs were aligned and compared with all aspects of an existing simulation activity offered to first-year nursing students at a large city-based university, prior to their first clinical placement in an Australian healthcare setting. Survey questions, comprised of Likert scales and free-text responses, used at other sites were slightly modified for reference to simulation. Students' opinions about the refined simulation activity were collected via electronic survey immediately following the simulation and from focus groups. Template analysis, using the BPGs as existing or a priori thematic codes, enabled interpretation and illumination of the data from both sources. Few changes were made to the existing simulation plan and format. Students' responses from surveys ( n  = 367) and four focus groups indicated that all seven BPGs were applicable for simulations in guiding their learning, particularly in the affective domain, and assisting their perceived needs in preparing for upcoming clinical practice. Similarities were found in the intent of simulation and OSCEs informed by the BPGs to enable feedback to students about holistic practice across affective, cognitive and psychomotor domains. The