WorldWideScience

Sample records for energy transducing enzyme

  1. An enzyme logic bioprotonic transducer

    Energy Technology Data Exchange (ETDEWEB)

    Miyake, Takeo; Keene, Scott; Deng, Yingxin; Rolandi, Marco, E-mail: rolandi@uw.edu [Department of Materials Science and Engineering, University of Washington, Seattle, Washington 98195-2120 (United States); Josberger, Erik E. [Department of Materials Science and Engineering, University of Washington, Seattle, Washington 98195-2120 (United States); Department of Electrical Engineering, University of Washington, Seattle, Washington 98195-2500 (United States)

    2015-01-01

    Translating ionic currents into measureable electronic signals is essential for the integration of bioelectronic devices with biological systems. We demonstrate the use of a Pd/PdH{sub x} electrode as a bioprotonic transducer that connects H{sup +} currents in solution into an electronic signal. This transducer exploits the reversible formation of PdH{sub x} in solution according to PdH↔Pd + H{sup +} + e{sup −}, and the dependence of this formation on solution pH and applied potential. We integrate the protonic transducer with glucose dehydrogenase as an enzymatic AND gate for glucose and NAD{sup +}. PdH{sub x} formation and associated electronic current monitors the output drop in pH, thus transducing a biological function into a measurable electronic output.

  2. The Evolution of Energy-Transducing Systems. Studies with Archaebacteria

    Science.gov (United States)

    Stan-Lotter, Helga

    1996-01-01

    The dicyclohexyl carbodiimide (DCCD)- binding site of the membrane ATPase from Halobacterium saccharovorum was investigated during earlier periods of this Cooperative Agreement and was localized to a cyanogen bromide fragment of subunit 2 from amino acids 379 (Glu) to 442 (Met). Although the exact position of the reactive amino acid (probably a glutamic acid) has not yet been determined, the data, together with recently obtained immuno reactions and sequences of Cyanogen Bromide (CNBr) fragments from E.coli F-ATPase, suggested subunit interactions in the halobacterial ATPase which had not been recognized before. They also provided evidence for the presence of a gamma subunit in the halobacterial ATPase, and for a stretch of a amino acids similar to the 'catch' between beta and gamma in bovine F-ATPase. The evolutionary implications of these findings are twofold: first, halobacterial (or archaebacterial) ATPases appear as complex as those from higher organisms - no simpler versions of these membrane enzymes are known to date; second, a monophyletic origin of the energy-transducing ATPases is becoming more apparent, and - together with other data - the split into V- and F-ATPases may have occurred much later than had been previously thought (i.e., after the split into Archaea and Bacteria). Other work included the characterization of an extremely halophilic isolate (Halococcus salifodinae ) from Permian salt sediments. This organism appeared to be an autotrophic halobacterium; its incorporation of C02 was investigated.

  3. Thermal energy harvesters with piezoelectric or electrostatic transducer

    Science.gov (United States)

    Prokaryn, Piotr; Domański, Krzysztof; Marchewka, Michał; Tomaszewski, Daniel; Grabiec, Piotr; Puscasu, Onoriu; Monfray, Stéphane; Skotnicki, Thomas

    2014-08-01

    This paper describes the idea of the energy harvester which converts thermal gradient present in environment into electricity. Two kinds of such devices are proposed and their prototypes are shown and discussed. The main parts of harvesters are bimetallic spring, piezoelectric transducer or electrostatic transducer with electret. The applied piezomembrane was commercial available product but electrets was made by authors. In the paper a fabrication procedure of electrets formed by the corona discharge process is described. Devices were compared in terms of generated power, charging current, and the voltage across a storage capacitor.

  4. Development and research of in-core transducers at IAE (Institute of Atomic Energy)

    International Nuclear Information System (INIS)

    Huang Yucai; Qian Shunfa; Jia Guozhen

    1989-10-01

    The development of in-core transducers at IAE (Institute of Atomic Energy) and their applications in in-pile fuel assembly test are mentioned. These transducers include mainly tubed tungsten-rhenium thermocouple assembly, displacement transducer of linear variable differential transformer, pressure transducer of membrane type, gamma thermometer, turbine flow meter, self-powered neutron detector etc

  5. Energy harvesting for wireless sensors by using piezoelectric transducers

    Energy Technology Data Exchange (ETDEWEB)

    Duerager, Christian [Empa, Swiss Federal Laboratories for Materials Science and Technology, Duebendorf (Switzerland)

    2012-07-01

    Wireless sensor technology, which integrates transducers, measurement electronics and wireless communication, has become increasingly vital in structural health monitoring (SHM) applications. Compared to traditional wired systems, wireless solutions reduce the installation time and costs and are not subjected to breakage caused by harsh weather conditions or other extreme events. Because of the low installation costs, wireless sensor networks allow the deployment of a big number of wireless sensor nodes on the structures. Moreover, the nodes can be placed on particularly critical components of the structure difficult to reach by wires. In most of the cases the power supply are conventional batteries, which could be a problem because of their finite life span. Furthermore, in the case of wireless sensor nodes located on structures, it is often advantageous to embed them, which makes an access impossible. Therefore, if a method of obtaining the untapped energy surrounding these sensors was implemented, significant life could be added to the power supply. Various approaches to energy harvesting and energy storage are discussed and limitations associated with the current technology are addressed. In this paper we first discuss the research that has been performed in the area of energy harvesting for wireless sensor technologies by using the ambient vibration energy. In many cases the energy produced by the ambient vibrations is far too small to directly power a wireless sensor node. Therefore, in a second step we discuss the development process for an electronic energy harvesting circuit optimized for piezoelectric transducers. In the last part of this paper an experiment with different piezoelectric transducers and their applicability for energy harvesting applications on vibrating structures will be discussed. (orig.)

  6. Phased transducer array for acoustic energy harvesting inside an MRI machine

    NARCIS (Netherlands)

    Klymko, V.; Roes, M.G.L.; Duivenbode, van J.; Lomonova, E.

    2013-01-01

    In this study, an array of piezoelectric speakers is used to focus acoustic energy on a single transducer that acts as a harvester. The transmitting transducers are located along a curve that fits inside the magnetic resonance interferometer (MRI) torus interior. The numerical results for the

  7. Illustrating Enzyme Inhibition Using Gibbs Energy Profiles

    Science.gov (United States)

    Bearne, Stephen L.

    2012-01-01

    Gibbs energy profiles have great utility as teaching and learning tools because they present students with a visual representation of the energy changes that occur during enzyme catalysis. Unfortunately, most textbooks divorce discussions of traditional kinetic topics, such as enzyme inhibition, from discussions of these same topics in terms of…

  8. Enzyme Catalysis and the Gibbs Energy

    Science.gov (United States)

    Ault, Addison

    2009-01-01

    Gibbs-energy profiles are often introduced during the first semester of organic chemistry, but are less often presented in connection with enzyme-catalyzed reactions. In this article I show how the Gibbs-energy profile corresponds to the characteristic kinetics of a simple enzyme-catalyzed reaction. (Contains 1 figure and 1 note.)

  9. Gating energies and forces of the mammalian hair cell transducer channel and related hair bundle mechanics

    NARCIS (Netherlands)

    van Netten, SM; Kros, CJ

    2000-01-01

    We quantified the molecular energies and forces involved in opening and closing of mechanoelectrical transducer channels in hair cells using a novel generally applicable method. It relies on a thermodynamic description of the free energy of an ion channel in terms of its open probability. The

  10. Adaptive acoustic energy delivery to near and far fields using foldable, tessellated star transducers

    Science.gov (United States)

    Zou, Chengzhe; Harne, Ryan L.

    2017-05-01

    Methods of guiding acoustic energy arbitrarily through space have long relied on digital controls to meet performance needs. Yet, more recent attention to adaptive structures with unique spatial configurations has motivated mechanical signal processing (MSP) concepts that may not be subjected to the same functional and performance limitations as digital acoustic beamforming counterparts. The periodicity of repeatable structural reconfiguration enabled by origami-inspired tessellated architectures turns attention to foldable platforms as frameworks for MSP development. This research harnesses principles of MSP to study a tessellated, star-shaped acoustic transducer constituent that provides on-demand control of acoustic energy guiding via folding-induced shape reconfiguration. An analytical framework is established to probe the roles of mechanical and acoustic geometry on the far field directivity and near field focusing of sound energy. Following validation by experiments and verification by simulations, parametric studies are undertaken to uncover relations between constituent topology and acoustic energy delivery to arbitrary points in the free field. The adaptations enabled by folding of the star-shaped transducer reveal capability for restricting sound energy to angular regions in the far field while also introducing means to modulate sound energy by three orders-of-magnitude to locations near to the transducer surface. In addition, the modeling philosophy devised here provides a valuable approach to solve general sound radiation problems for foldable, tessellated acoustic transducer constituents of arbitrary geometry.

  11. Involvement of methyltransferases enzymes during the energy

    African Journals Online (AJOL)

    Mgina

    INVOLVEMENT OF METHYLTRANSFERASES ENZYMES DURING THE. ENERGY METABOLISM OF ..... cell extract still exhibited relatively high methanogenesis with methanol (Fig ... product CH3-CoM into methane (see Fig. 1). The HS-CoM ...

  12. CMOS circuits for electromagnetic vibration transducers interfaces for ultra-low voltage energy harvesting

    CERN Document Server

    Maurath, Dominic

    2015-01-01

    Chip-integrated power management solutions are a must for ultra-low power systems. This enables not only the optimization of innovative sensor applications. It is also essential for integration and miniaturization of energy harvesting supply strategies of portable and autonomous monitoring systems. The book particularly addresses interfaces for energy harvesting, which are the key element to connect micro transducers to energy storage elements. Main features of the book are: - A comprehensive technology and application review, basics on transducer mechanics, fundamental circuit and control design, prototyping and testing, up to sensor system supply and applications. - Novel interfacing concepts - including active rectifiers, MPPT methods for efficient tracking of DC as well as AC sources, and a fully-integrated charge pump for efficient maximum AC power tracking at sub-100µW ultra-low power levels. The chips achieve one of widest presented operational voltage range in standard CMOS technology: 0.44V to over...

  13. Voltammetric enzyme sensor for urea using mercaptohydroquinone-modified gold electrode as the base transducer.

    Science.gov (United States)

    Mizutani, F; Yabuki, S; Sato, Y

    1997-01-01

    A voltammetric urea-sensing electrode was prepared by combining a lipid-attached urease layer with a 2,5-dihydroxythiophenol-modified gold electrode. A self-assembled monolayer of dihydroxythiophenol was prepared on the gold surface by soaking the electrode into an ethanolic solution containing the modifier. A layer of the lipid-attached enzyme and that of acetyl cellulose overcoat were successively made on the dihydroxythiophenol-modified electrode by applying a dip-coating procedure. The addition of urea in a test solution (10 mM phosphate buffer, pH 7.0) brought about an increase of pH near the urease layer. The pH shift accompanied a negative shift of the anodic peak, which corresponded to the electro-oxidation of dihydroxyphenol moiety to form quinone, on the linear sweep voltammograms for the urease/dihydroxythiophenol electrode. The concentration of urea (0.2-5 mM) could be determined by measuring the electrode current at -0.05 V versus Ag/AgCl from the voltammogram. The electrode was applied to the determination of urea in human urine; the measurement of electrode current at such a low potential provided the urea determination without any electrochemical interference from L-ascorbic acid and uric acid.

  14. Vibration energy harvesting in a small channel fluid flow using piezoelectric transducer

    Energy Technology Data Exchange (ETDEWEB)

    Hassan, Md. Mehedi, E-mail: buetmehedi10@gmail.com; Hossain, Md. Yeam, E-mail: yeamhossain@gmail.com; Mazumder, Rakib, E-mail: rakibmazumder46075@gmail.com; Rahman, Roussel, E-mail: roussel.rahman@gmail.com; Rahman, Md. Ashiqur, E-mail: ashiqurrahman@me.buet.ac.bd [Department of Mechanical Engineering, Bangladesh University of Engineering and Technology (BUET), Dhaka-1000 (Bangladesh)

    2016-07-12

    This work is aimed at developing a way to harvest energy from a fluid stream with the application of piezoelectric transducers in a small channel. In this COMSOL Multiphysics based simulation study, it is attempted to harvest energy from the abundant renewable source of energy available in the form of kinetic energy of naturally occurring flow of fluids. The strategy involves harnessing energy from a fluid-actuator through generation of couples, eddies and vortices, resulting from the stagnation and separation of flow around a semi-circular bluff-body attached to a cantilever beam containing a piezoceramic layer. Fluctuation of fluidic pressure impulse on the beam due to vortex shedding and varying lift forces causes the flexible cantilever beam to oscillate in the direction normal to the fluid flow in a periodic manner. The periodic application and release of a mechanical strain upon the beam effected a generation of electric potential within the piezoelectric layer, thus enabling extraction of electrical energy from the kinetic energy of the fluid. The piezoelectric material properties and transducer design are kept unchanged throughout the study, whereas the configuration is tested with different fluids and varying flow characteristics. The size and geometry of the obstructing entity are systematically varied to closely inspect the output from different iterations and for finding the optimum design parameters. The intermittent changes in the generated forces and subsequent variation in the strain on the beam are also monitored to find definitive relationship with the electrical energy output.

  15. A system of two piezoelectric transducers and a storage circuit for wireless energy transmission through a thin metal wall.

    Science.gov (United States)

    Hu, Hongping; Hu, Yuantai; Chen, Chuanyao; Wang, Ji

    2008-10-01

    A system to wirelessly convey electric energy through a thin metal wall is proposed in the paper, where 2 piezoelectric transducers are used to realize energy transformation between electric and mechanical, and a rechargeable battery is employed to store the transmitted energy. To integrate them as a whole, an interface of a modulating circuit is applied between the transducer system and the storage battery. In addition, a synchronized switch harvesting on inductor in parallel with the transducer system is introduced to artificially extend the closed interval of the modulating circuit. The process of transmitting energy is computed, and the performance of the transducer system is optimized in detail for a prescribed external electric source. The results obtained are useful for understanding and designing wireless energy supply systems.

  16. Influence of the α-, β- and γ-subunits of the energy-transducing adenosine triphosphatase from Micrococcus lysodeikticus in the immunochemical properties of the protein and in their reconstitution studied by a radioimmunoassay method

    International Nuclear Information System (INIS)

    Larraga, V.; Mollinedo, F.; Rubio, N.; Munoz, E.

    1981-01-01

    A sensitive radioimmunoassay was developed for the energy-transducing adenosine triphosphatase (F 1 -ATPase, EC 3.6.1.3) of Micrococcus lysodeikticus and the assay was extended to the α-, β- and γ-subunits of the enzyme. These subunits were isolated and cross-reactions studied. (author)

  17. Influence of the. cap alpha. -,. beta. -, and. gamma. -subunits of the energy-transducing adenosine triphosphatase from Micrococcus lysodeikticus in the immunochemical properties of the protein and in their reconstitution studied by a radioimmunoassay method

    Energy Technology Data Exchange (ETDEWEB)

    Larraga, V; Mollinedo, F; Rubio, N; Munoz, E [Unidad de Biomembranas, Instituto de Inmunologia y Biologia Microbiana, Madrid (Spain)

    1981-03-01

    A sensitive radioimmunoassay was developed for the energy-transducing adenosine triphosphatase (F/sub 1/-ATPase, EC 3.6.1.3) of Micrococcus lysodeikticus and the assay was extended to the ..cap alpha..-, ..beta..-, and ..gamma..-subunits of the enzyme. These subunits were isolated and cross-reactions studied.

  18. Test rig with active damping control for the simultaneous evaluation of vibration control and energy harvesting via piezoelectric transducers

    OpenAIRE

    Perfetto, Sara; Rohlfing, Jens; Infante, Francesco; Mayer, Dirk; Herold, Sven

    2016-01-01

    Piezoelectric transducers can be used to harvest electrical energy from structural vibrations in order to power continuously operating condition monitoring systems local to where they operate. However, excessive vibrations can compromise the safe operation of mechanical systems. Therefore, absorbers are commonly used to control vibrations. With an integrated device, the mechanical energy that otherwise would be dissipated can be converted via piezoelectric transducers. Vibration absorbers are...

  19. Possibility of cellulose-based electro-active paper energy scavenging transducer.

    Science.gov (United States)

    Abas, Zafar; Kim, Heung Soo; Zhai, Lindong; Kim, Jaehwan; Kim, Joo Hyung

    2014-10-01

    In this paper, a cellulose-based Electro-Active Paper (EAPap) energy scavenging transducer is presented. Cellulose is proven as a smart material, and exhibits piezoelectric effect. Specimens were prepared by coating gold electrodes on both sides of cellulose film. The fabricated specimens were tested by a base excited aluminum cantilever beam at resonant frequency. Different tests were performed with single and multiple parallel connected electrodes coated on the cellulose film. A maximum of 131 mV output voltage was measured, when three electrodes were connected in parallel. It was observed that voltage output increases significantly with the area of electrodes. From these results, it can be concluded that the piezoelectricity of cellulose-based EAPap can be used in energy transduction application.

  20. Investigations of DC power supplies with optoelectronic transducers and RF energy converters

    Science.gov (United States)

    Guzowski, B.; Gozdur, R.; Bernacki, L.; Lakomski, M.

    2016-04-01

    Fiber Distribution Cabinets (FDC) monitoring systems are increasingly popular. However it is difficult to realize such system in passive FDC, due to lack of source of power supply. In this paper investigation of four different DC power supplies with optoelectronic transducers is described. Two converters: photovoltaic power converter and PIN photodiode can convert the light transmitted through the optical fiber to electric energy. Solar cell and antenna RF-PCB are also tested. Results presented in this paper clearly demonstrate that it is possible to build monitoring system in passive FDC. During the tests maximum obtained output power was 11 mW. However all converters provided enough power to excite 32-bit microcontroller with ARM-cores and digital thermometer.

  1. Lead-free piezoelectric transducers for vibration-based energy harvesting devices

    Energy Technology Data Exchange (ETDEWEB)

    Roescher, Mark

    2011-11-15

    Future applications like piezoelectric energy harvesters in addition with increasing environmental awareness ultimately demand novel sophisticated material systems in the field of piezoelectrics as an alternative to the long-established system lead-zirconate-titanate. In this publication state-of-the-art microgenerators have been designed to possess nonlinear Duffing oscillator characteristics. It is shown by measurement and simulation that lead-zirconate-titanate may hence no longer be the first choice in material selection for a piezoelectric microgenerator. Polyvinylidene fluoride has been integrated in a piezoelectric microgenerator and identified as an extraordinarily promising material system for transducer applications being highly insusceptible to stretching induced material failure. Finally, a fundamentally new chemical synthesis approach has been developed for the fabrication of potassium-sodium-niobate films that may also be suitable for other complex oxides.

  2. Temperature dependence of energy-transducing functions and inhibitor sensitivity in chloroplasts

    Energy Technology Data Exchange (ETDEWEB)

    Schuurmans, J.J.; Veerman, E.C.I.; Francke, J.A.; Torres-Pereira, J.M.G.; Kraayenhof, R.

    1984-01-01

    A comparative analysis of the temperature dependence of energy-transducing reactions in spinach (Spinacia oleracea) chloroplasts and their sensitivity for uncouplers and energy-transfer inhibitors at different temperatures is presented. Arrhenius plots reveal two groups of transitions, around 19/sup 0/C and around 12/sup 0/C. Activities that show transitions around 19/sup 0/C include linear electron flow from water to ferricyanide, its coupled photophosphorylation, the dark-release of the fluorescent probe atebrin, and the slow component of the 515 nm (carotenoid) absorbance decay after a flash. The transitions around 12/sup 0/C are observed with pyocyanine-mediated cyclic photophosphorylation, light- and dithioerythritol-activated ATP hydrolysis, the dark-release of protons, and the fast 515 nm decay component. It is suggested that both groups of temperature transitions are determined by proton displacements in different domains of the exposed thylakoid membranes. The effects of various uncouplers and an energy-transfer inhibitor are temperature dependent. Some uncouplers also show a different relative inhibition of proton uptake and ATP synthesis at lower temperatures. The efficiency of energy transduction (ATP/e/sub 3/) varied with temperature and was optimal around 10/sup 0/C.

  3. Test rig with active damping control for the simultaneous evaluation of vibration control and energy harvesting via piezoelectric transducers

    International Nuclear Information System (INIS)

    Perfetto, S; Rohlfing, J; Infante, F; Mayer, D; Herold, S

    2016-01-01

    Piezoelectric transducers can be used to harvest electrical energy from structural vibrations in order to power continuously operating condition monitoring systems local to where they operate. However, excessive vibrations can compromise the safe operation of mechanical systems. Therefore, absorbers are commonly used to control vibrations. With an integrated device, the mechanical energy that otherwise would be dissipated can be converted via piezoelectric transducers. Vibration absorbers are designed to have high damping factors. Hence, the integration of transducers would lead to a low energy conversion. Efficient energy harvesters usually have low damping capabilities; therefore, they are not effective for vibration suppression. Thus, the design of an integrated device needs to consider the two conflicting requirements on the damping. This study focuses on the development of a laboratory test rig with a host structure and a vibration absorber with tunable damping via an active relative velocity feedback. A voice coil actuator is used for this purpose. To overcome the passive damping effects of the back electromagnetic force a novel voltage feedback control is proposed, which has been validated both in simulation and experimentally. The aim of this study is to have a test rig ready for the introduction of piezo-transducers and available for future experimental evaluations of the damping effect on the effectiveness of vibration reduction and energy harvesting efficiency. (paper)

  4. Test rig with active damping control for the simultaneous evaluation of vibration control and energy harvesting via piezoelectric transducers

    Science.gov (United States)

    Perfetto, S.; Rohlfing, J.; Infante, F.; Mayer, D.; Herold, S.

    2016-09-01

    Piezoelectric transducers can be used to harvest electrical energy from structural vibrations in order to power continuously operating condition monitoring systems local to where they operate. However, excessive vibrations can compromise the safe operation of mechanical systems. Therefore, absorbers are commonly used to control vibrations. With an integrated device, the mechanical energy that otherwise would be dissipated can be converted via piezoelectric transducers. Vibration absorbers are designed to have high damping factors. Hence, the integration of transducers would lead to a low energy conversion. Efficient energy harvesters usually have low damping capabilities; therefore, they are not effective for vibration suppression. Thus, the design of an integrated device needs to consider the two conflicting requirements on the damping. This study focuses on the development of a laboratory test rig with a host structure and a vibration absorber with tunable damping via an active relative velocity feedback. A voice coil actuator is used for this purpose. To overcome the passive damping effects of the back electromagnetic force a novel voltage feedback control is proposed, which has been validated both in simulation and experimentally. The aim of this study is to have a test rig ready for the introduction of piezo-transducers and available for future experimental evaluations of the damping effect on the effectiveness of vibration reduction and energy harvesting efficiency.

  5. Energy harvesting with stacked dielectric elastomer transducers: Nonlinear theory, optimization, and linearized scaling law

    Science.gov (United States)

    Tutcuoglu, A.; Majidi, C.

    2014-12-01

    Using principles of damped harmonic oscillation with continuous media, we examine electrostatic energy harvesting with a "soft-matter" array of dielectric elastomer (DE) transducers. The array is composed of infinitely thin and deformable electrodes separated by layers of insulating elastomer. During vibration, it deforms longitudinally, resulting in a change in the capacitance and electrical enthalpy of the charged electrodes. Depending on the phase of electrostatic loading, the DE array can function as either an actuator that amplifies small vibrations or a generator that converts these external excitations into electrical power. Both cases are addressed with a comprehensive theory that accounts for the influence of viscoelasticity, dielectric breakdown, and electromechanical coupling induced by Maxwell stress. In the case of a linearized Kelvin-Voigt model of the dielectric, we obtain a closed-form estimate for the electrical power output and a scaling law for DE generator design. For the complete nonlinear model, we obtain the optimal electrostatic voltage input for maximum electrical power output.

  6. A sandwiched piezoelectric transducer with flex end-caps for energy harvesting in large force environments

    International Nuclear Information System (INIS)

    Kuang, Yang; Daniels, Alice; Zhu, Meiling

    2017-01-01

    This paper presents a sandwiched piezoelectric transducer (SPT) for energy harvesting in large force environments with increased load capacity and electric power output. The SPT uses (1) flex end-caps to amplify the applied load force so as to increase its power output and (2) a sandwiched piezoelectric-substrate structure to reduce the stress concentration in the piezoelectric material so as to increase the load capacity. A coupled piezoelectric-circuit finite element model (CPC-FEM) was developed, which is able to directly predict the electric power output of the SPT connected to a load resistor. The CPC-FEM was used to study the effects of various parameters of the SPT on the performance to obtain an optimal design. These parameters included the substrate thickness, the end-cap material and thickness, the electrode length, the joint length, the end-cap internal angle and the PZT thickness. A prototype with optimised parameters was tested on a loading machine, and the experimental results were compared with simulation. A good agreement was observed between simulation and experiment. When subjected to a 1 kN 2 Hz sinusoidal force applied by the loading machine, the SPT produced an average power of 4.68 mW. The application of the SPT as a footwear energy harvester was demonstrated by fitting the SPT into a boot and performing the tests on a treadmill, and the SPT generated an average power of 2.5 mW at a walking speed of 4.8 km h −1 . (paper)

  7. Involvement of methyltransferases enzymes during the energy ...

    African Journals Online (AJOL)

    The methyl group transfer from dimethylsulfide (DMS), trimethylamine and methanol to 2-mercaptoethanesulfonic acid (coenzyme M) were investigated from cell extracts of Methanosarcina semesiae sp. nov. to evaluate whether the enzyme systems involved were constitutive or inductive. The extracts from cells grown on ...

  8. Pressure transducers

    International Nuclear Information System (INIS)

    Gomes, A.V.

    1975-01-01

    Strain gauges pressure transducers types are presented. Models, characteristics and calibration procedures were also analysed. Initially, a theoretical study was accomplished to evaluate metallic alloys behavior on sensing elements manufacturing, and diaphragm was used as deflecting elements. Electrical models for potenciometric transducers were proposed at the beginning and subsequently comproved according our experiments. Concerning bridge transducers, existing models confirmed the conditions of linearity and sensitivity related to the electrical signal. All the work done was of help on the calibration field and pressure measurements employing unbounded strain gauge pressure transducers

  9. A Low-Power CMOS Piezoelectric Transducer Based Energy Harvesting Circuit for Wearable Sensors for Medical Applications

    Directory of Open Access Journals (Sweden)

    Taeho Oh

    2017-12-01

    Full Text Available Piezoelectric vibration based energy harvesting systems have been widely utilized and researched as powering modules for various types of sensor systems due to their ease of integration and relatively high energy density compared to RF, thermal, and electrostatic based energy harvesting systems. In this paper, a low-power CMOS full-bridge rectifier is presented as a potential solution for an efficient energy harvesting system for piezoelectric transducers. The energy harvesting circuit consists of two n-channel MOSFETs (NMOS and two p-channel MOSFETs (PMOS devices implementing a full-bridge rectifier coupled with a switch control circuit based on a PMOS device driven by a comparator. With a load of 45 kΩ, the output rectifier voltage and the input piezoelectric transducer voltage are 694 mV and 703 mV, respectably, while the VOUT versus VIN conversion ratio is 98.7% with a PCE of 52.2%. The energy harvesting circuit has been designed using 130 nm standard CMOS process.

  10. Acoustic transducer

    Science.gov (United States)

    Drumheller, Douglas S.

    2000-01-01

    An active acoustic transducer tool for use down-hole applications. The tool includes a single cylindrical mandrel including a shoulder defining the boundary of a narrowed portion over which is placed a sandwich-style piezoelectric tranducer assembly. The piezoelectric transducer assembly is prestressed by being placed in a thermal interference fit between the shoulder of the mandrel and the base of an anvil which is likewise positioned over the narrower portion of the mandrel. In the preferred embodiment, assembly of the tool is accomplished using a hydraulic jack to stretch the mandrel prior to emplacement of the cylindrical sandwich-style piezoelectric transducer assembly and anvil. After those elements are positioned and secured, the stretched mandrel is allowed to return substantially to its original (pre-stretch) dimensions with the result that the piezoelectric transducer elements are compressed between the anvil and the shoulder of the mandrel.

  11. Coaxial Transducer

    National Research Council Canada - National Science Library

    Ruffa, Anthony A

    2008-01-01

    The invention as disclosed is of a coaxial transducer that uses lead zirconate titanate ceramic or other suitable material as an isolator between the conductors in a coaxial cable to transmit acoustic...

  12. The dynamic basis of energy transduction in enzymes.

    Science.gov (United States)

    Somogyi, B; Welch, G R; Damjanovich, S

    1984-09-06

    The most important idea underlying our treatment herein is the unity of the enzyme molecule and the medium. Appreciation of this relationship is vital, if enzymology is to graduate from its present reductionistic status to a more holistic posture. Enzymes are biological entities firstly, and isolated objects of physicochemical analysis secondly. Perhaps the most crucial 'biological lesson', particularly apropos of enzymes in intermediary metabolism, concerns the 'cytosociology' of enzyme action in vivo [94,128]. The natural habitat of many enzymes in the living cell is far different from that in bulk aqueous solution in vitro. In order to obtain a real grasp of the nature of enzyme function, one must ultimately couch enzymology in concepts emerging from contemporary cell biology [95]. Notwithstanding, analysis precedes synthesis; and one must needs begin with the individual enzyme molecule. The trenchant efforts of the physical chemist and the organic chemist have produced a wealth of information on the nature of the binding and catalytic events at the enzyme active site. While it is not yet possible to explain precisely the complete sequence of events in the catalytic process, nevertheless, the basic mechanisms by which enzymes effect catalysis (i.e., reduce activation energy) now seem apparent [81,129]. The new frontier is to be found, in exploring the dynamic role of the protein matrix [17]. Not only does the protein provide the 3-D scaffolding for active-site processes, but, more importantly, it serves as the local solvent for the bound chemical subsystem. Thus, the dynamical aspects of enzyme catalysis (for thermally based systems) must arise from the fluctuational properties of the protein molecule. This notion is the common denominator in all of the models in subsection IIC. It is the anisotropic nature of this fluctuational behavior, which would characterize the energy-transduction phenomenon leading to localized catalytic events at the active-site. In

  13. Enzyme

    Science.gov (United States)

    Enzymes are complex proteins that cause a specific chemical change in all parts of the body. For ... use them. Blood clotting is another example of enzymes at work. Enzymes are needed for all body ...

  14. Magnetically coupled flextensional transducer for wideband vibration energy harvesting: Design, modeling and experiments

    Science.gov (United States)

    Zou, Hong-Xiang; Zhang, Wen-Ming; Li, Wen-Bo; Wei, Ke-Xiang; Hu, Kai-Ming; Peng, Zhi-Ke; Meng, Guang

    2018-03-01

    The combination of nonlinear bistable and flextensional mechanisms has the advantages of wide operating frequency and high equivalent piezoelectric constant. In this paper, three magnetically coupled flextensional vibration energy harvesters (MF-VEHs) are designed from three magnetically coupled vibration systems which utilize a magnetic repulsion, two symmetrical magnetic attractions and multi-magnetic repulsions, respectively. The coupled dynamic models are developed to describe the electromechanical transitions. Simulations under harmonic excitation and random excitation are carried out to investigate the performance of the MF-VEHs with different parameters. Experimental validations of the MF-VEHs are performed under different excitation levels. The experimental results verify that the developed mathematical models can be used to accurately characterize the MF-VEHs for various magnetic coupling modes. A comparison of three MF-VEHs is provided and the results illustrate that a reasonable arrangement of multiple magnets can reduce the threshold excitation intensity and increase the harvested energy.

  15. Stress wave focusing transducers

    Energy Technology Data Exchange (ETDEWEB)

    Visuri, S.R., LLNL

    1998-05-15

    Conversion of laser radiation to mechanical energy is the fundamental process behind many medical laser procedures, particularly those involving tissue destruction and removal. Stress waves can be generated with laser radiation in several ways: creation of a plasma and subsequent launch of a shock wave, thermoelastic expansion of the target tissue, vapor bubble collapse, and ablation recoil. Thermoelastic generation of stress waves generally requires short laser pulse durations and high energy density. Thermoelastic stress waves can be formed when the laser pulse duration is shorter than the acoustic transit time of the material: {tau}{sub c} = d/c{sub s} where d = absorption depth or spot diameter, whichever is smaller, and c{sub s} = sound speed in the material. The stress wave due to thermoelastic expansion travels at the sound speed (approximately 1500 m/s in tissue) and leaves the site of irradiation well before subsequent thermal events can be initiated. These stress waves, often evolving into shock waves, can be used to disrupt tissue. Shock waves are used in ophthalmology to perform intraocular microsurgery and photodisruptive procedures as well as in lithotripsy to fragment stones. We have explored a variety of transducers that can efficiently convert optical to mechanical energy. One such class of transducers allows a shock wave to be focused within a material such that the stress magnitude can be greatly increased compared to conventional geometries. Some transducer tips could be made to operate regardless of the absorption properties of the ambient media. The size and nature of the devices enable easy delivery, potentially minimally-invasive procedures, and precise tissue- targeting while limiting thermal loading. The transducer tips may have applications in lithotripsy, ophthalmology, drug delivery, and cardiology.

  16. Steerable Doppler transducer probes

    International Nuclear Information System (INIS)

    Fidel, H.F.; Greenwood, D.L.

    1986-01-01

    An ultrasonic diagnostic probe is described which is capable of performing ultrasonic imaging and Doppler measurement consisting of: a hollow case having an acoustic window which passes ultrasonic energy and including chamber means for containing fluid located within the hollow case and adjacent to a portion of the acoustic window; imaging transducer means, located in the hollow case and outside the fluid chamber means, and oriented to direct ultrasonic energy through the acoustic window toward an area which is to be imaged; Doppler transducer means, located in the hollow case within the fluid chamber means, and movably oriented to direct Doppler signals through the acoustic window toward the imaged area; means located within the fluid chamber means and externally controlled for controllably moving the Doppler transducer means to select one of a plurality of axes in the imaged area along which the Doppler signals are to be directed; and means, located external to the fluid chamber means and responsive to the means for moving, for providing an indication signal for identifying the selected axis

  17. Transducer-Mounting Fixture

    Science.gov (United States)

    Spiegel, Kirk W.

    1990-01-01

    Transducer-mounting fixture holds transducer securely against stud. Projects only slightly beyond stud after installation. Flanged transducer fits into fixture when hinged halves open. When halves reclosed, fixture tightened onto threaded stud until stud makes contact with transducer. Knurled area on fixture aids in tightening fixture on stud.

  18. Energy conservation and maximal entropy production in enzyme reactions.

    Science.gov (United States)

    Dobovišek, Andrej; Vitas, Marko; Brumen, Milan; Fajmut, Aleš

    2017-08-01

    A procedure for maximization of the density of entropy production in a single stationary two-step enzyme reaction is developed. Under the constraints of mass conservation, fixed equilibrium constant of a reaction and fixed products of forward and backward enzyme rate constants the existence of maximum in the density of entropy production is demonstrated. In the state with maximal density of entropy production the optimal enzyme rate constants, the stationary concentrations of the substrate and the product, the stationary product yield as well as the stationary reaction flux are calculated. The test, whether these calculated values of the reaction parameters are consistent with their corresponding measured values, is performed for the enzyme Glucose Isomerase. It is found that calculated and measured rate constants agree within an order of magnitude, whereas the calculated reaction flux and the product yield differ from their corresponding measured values for less than 20 % and 5 %, respectively. This indicates that the enzyme Glucose Isomerase, considered in a non-equilibrium stationary state, as found in experiments using the continuous stirred tank reactors, possibly operates close to the state with the maximum in the density of entropy production. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Microhydraulic transducer technology for actuation and power generation

    Science.gov (United States)

    Hagood, Nesbitt W.; Roberts, David C.; Saggere, Laxminarayana; Breuer, Kenneth S.; Chen, Kuo-Shen; Carretero, Jorge A.; Li, Hanqing; Mlcak, Richard; Pulitzer, Seward W.; Schmidt, Martin A.; Spearing, S. Mark; Su, Yu-Hsuan

    2000-06-01

    The paper introduces a novel transducer technology, called the solid-state micro-hydraulic transducer, currently under development at MIT. The new technology is enabled through integration of micromachining technology, piezoelectrics, and microhydraulic concepts. These micro-hydraulic transducers are capable of bi-directional electromechanical energy conversion, i.e., they can operate as both an actuator that supplies high mechanical force in response to electrical input and an energy generator that transduces electrical energy from mechanical energy in the environment. These transducers are capable of transducing energy at very high specific power output in the order of 1 kW/kg, and thus, they have the potential to enable many novel applications. The concept, the design, and the potential applications of the transducers are presented. Present efforts towards the development of these transducers, and the challenges involved therein, are also discussed.

  20. Coalgebraising subsequential transducers

    NARCIS (Netherlands)

    H.H. Hansen (Helle); J. Adamek; C.A. Kupke (Clemens)

    2008-01-01

    htmlabstractSubsequential transducers generalise both classic deterministic automata and Mealy/Moore type state machines by combining (input) language recognition with transduction. In this paper we show that normalisation and taking differentials of subsequential transducers and their underlying

  1. Coalgebraising Subsequential Transducers

    NARCIS (Netherlands)

    Hansen, H.H.

    2008-01-01

    Subsequential transducers generalise both classic deterministic automata and Mealy/Moore type state machines by combining (input) language recognition with transduction. In this paper we show that normalisation and taking differentials of subsequential transducers and their underlying structures can

  2. Driving electrostatic transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2013-01-01

    Electrostatic transducers represent a very interesting alternative to the traditional inefficient electrodynamic transducers. In order to establish the full potential of these transducers, power amplifiers which fulfill the strict requirements imposed by such loads (high impedance, frequency...... depended, nonlinear and high bias voltage for linearization) must be developed. This paper analyzes power stages and bias configurations suitable for driving an electrostatic transducer. Measurement results of a 300 V prototype amplifier are shown. Measuring THD across a high impedance source is discussed...

  3. Effect of fat source, energy level and enzyme supplementation and ...

    African Journals Online (AJOL)

    Martina

    2014-09-24

    Sep 24, 2014 ... ISSN 0375-1589 (print), ISSN 2221-4062 (online) ... were fed ad libitum in cages from 1 to 30 days of age. ... diet, improve efficiency and increase nutrient digestibility in broilers (Baião & Lara, 2005; Fascina et al., ... feed to reduce the cost per ton of feed and then, by adding enzymes, restores the nutritional ...

  4. Planar integrated optical waveguide used as a transducer to yield chemical information: detection of the activity of proteolytic enzymes e.g. serine-proteases

    Science.gov (United States)

    Zhylyak, Gleb; Ramoz-Perez, Victor; Linnhoff, Michael; Hug, Thomas; Citterio, Daniel; Spichiger-Keller, Ursula E.

    2005-03-01

    The paper shows the very first results of a feasibility study where the activity of proteolytic enzymes towards dye-labelled artificial substrates immobilized on the surface of planar optical Ta2O5 waveguide was investigated. Within this project, a chromophore label was developed, synthesized and attached to the carboxy-terminus of specific tripeptides. The goal was to develop a highly sensitive optical assay in order to monitor the activity of serine-proteases by cleavage of the amide bond between peptide and chromophore. On the one hand, a strategy was developed to immobilize the labeled tripeptide unto integrated planar waveguides. On the other hand, an instrument, the so-called "chip-reader" was developed to detect the biological process on the surface of the integrated planar optical waveguide. Surface characteristics were analyzed by XPS, TOF-SIMS and contact angle measurements. A comparison between the effectivity of ATR-photometry on chip using TE0 mode and photometry in transmission mode is discussed.

  5. Model of a Piezoelectric Transducer

    Science.gov (United States)

    Goodenow, Debra

    2004-01-01

    It's difficult to control liquid and gas in propellant tanks in zero gravity. A possible a design would utilize acoustic liquid manipulation (ALM) technology which uses ultrasonic beams conducted through a liquid and solid media, to push gas bubbles in the liquid to desirable locations. We can propel and control the bubble with acoustic radiation pressure by aiming the acoustic waves on the bubble s surface. This allows us to design a so called smart tank in which the ALM devices transfer the gas to the outer wall of the tank and isolating the liquid in the center. Because the heat transfer rate of a gas is lower of that of the liquid it would substantially decrease boil off and provide of for a longer storage life. The ALM beam is composed of little wavelets which are individual waves that constructively interfere with each other to produce a single, combined acoustic wave front. This is accomplished by using a set of synchronized ultrasound transducers arranged in an array. A slight phase offset of these elements allows us to focus and steer the beam. The device that we are using to produce the acoustic beam is called the piezoelectric transducer. This device converts electrical energy to mechanical energy, which appears in the form of acoustic energy. Therefore the behavior of the device is dependent on both the mechanical characteristics, such as its density, cross-sectional area, and its electrical characteristics, such as, electric flux permittivity and coupling factor. These devices can also be set up in a number of modes which are determined by the way the piezoelectric device is arranged, and the shape of the transducer. For this application we are using the longitudinal or thickness mode for our operation. The transducer also vibrates in the lateral mode, and one of the goals of my project is to decrease the amount of energy lost to the lateral mode. To model the behavior of the transducers I will be using Pspice, electric circuit modeling tool, to

  6. Transducer handbook user's directory of electrical transducers

    CERN Document Server

    Boyle, H B

    2013-01-01

    When selecting or using a particular type of transducer or sensor, there are a number of factors which must be considered. The question is not only for what kind of measurement, but under what physical conditions, constraints of accuracy, and to meet which service requirements, is a transducer needed? This handbook is designed to meet the selection needs of anyone specifying or using transducers with an electrical output. Each transducer is described in an easy-to-use tabular format, giving all of the necessary data including operating principles, applications, range limits, errors, over-range protection, supply voltage requirements, sensitivities, cross sensitivities, temperature ranges and sensitivities and signal conditioning needs. The author has added notes that reflect his broad practical experience. Added to this is an extensive worldwide suppliers directory.

  7. Beyond triglyceride synthesis: the dynamic functional roles of MGAT and DGAT enzymes in energy metabolism.

    Science.gov (United States)

    Shi, Yuguang; Cheng, Dong

    2009-07-01

    Monoacyglycerol acyltransferases (MGATs) and diacylglycerol acyltransferases (DGATs) catalyze two consecutive steps of enzyme reactions in the synthesis of triacylglycerols (TAGs). The metabolic complexity of TAG synthesis is reflected by the presence of multiple isoforms of MGAT and DGAT enzymes that differ in catalytic properties, subcellular localization, tissue distribution, and physiological functions. MGAT and DGAT enzymes play fundamental roles in the metabolism of monoacylglycerol (MAG), diacylglycerol (DAG), and triacylglycerol (TAG) that are involved in many aspects of physiological functions, such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, signal transduction, satiety, and lactation. The recent progress in the phenotypic characterization of mice deficient in MGAT and DGAT enzymes and the development of chemical inhibitors have revealed important roles of these enzymes in the regulation of energy homeostasis and insulin sensitivity. Consequently, selective inhibition of MGAT or DGAT enzymes by synthetic compounds may provide novel treatment for obesity and its related metabolic complications.

  8. Optimum Operating Conditions of (PbxX1−x(ZryTizY1−y−z Piezoelectric Transducer for Vibrational Energy Harvesting Applications

    Directory of Open Access Journals (Sweden)

    Funda Demir

    2016-01-01

    Full Text Available The electrical energy production capability of bimorph (PbxX1-x(ZryTizY1-y-z fiber composite piezoelectric transducer has been investigated for energy harvesting applications. The material has been analyzed under different frequencies, bending amounts, and temperatures. The operating conditions for maximum electrical energy outcome have been determined. The natural frequencies of oscillations in the macro dimensions have been found to be inversely proportional to the length of the material. On the other hand, the voltage output with respect to the oscillation frequency exhibits an interesting behavior such that the characteristic curve shifts to higher frequencies as the bending radius is decreased. This behavior has been interpreted as a result of possible overtone transitions of the oscillations to a stiffer mode. The increasing temperature has been observed to have a negative effect on the piezoelectric energy harvesting property. When the determined optimum conditions were utilized, the amount of electrical energy stored in 6300 s by an energy harvester circuitry has been found to be 0.8 J.

  9. Handbook of force transducers

    CERN Document Server

    Stefanescu, Dan Mihai

    2011-01-01

    Part I introduces the basic ""Principles and Methods of Force Measurement"" acording to a classification into a dozen of force transducers types: resistive, inductive, capacitive, piezoelectric, electromagnetic, electrodynamic, magnetoelastic, galvanomagnetic (Hall-effect), vibrating wires, (micro)resonators, acoustic and gyroscopic. Two special chapters refer to force balance techniques and to combined methods in force measurement. Part II discusses the ""(Strain Gauge) Force Transducers Components"", evolving from the classical force transducer to the digital / intelligent one, with the inco

  10. Irradiation Testing of Ultrasonic Transducers

    International Nuclear Information System (INIS)

    Daw, J.; Rempe, J.; Palmer, J.; Tittmann, B.; Reinhardt, B.; Kohse, G.; Ramuhalli, P.; Montgomery, R.; Chien, H.T.; Villard, J.F.

    2013-06-01

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of numerous parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of single, small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of existing knowledge of ultrasonic transducer material survivability under irradiation conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate promising magnetostrictive and piezoelectric transducer performance in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 10 21 n/cm 2 (E> 0.1 MeV). This test will be an instrumented lead test; and real-time transducer performance data will be collected along with temperature and neutron and gamma flux data. By characterizing magnetostrictive and piezoelectric transducer survivability during irradiation, test results will enable the development of novel radiation tolerant ultrasonic sensors for use in Material and Test Reactors (MTRs). The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers. (authors)

  11. Programming macro tree transducers

    DEFF Research Database (Denmark)

    Bahr, Patrick; Day, Laurence E.

    2013-01-01

    transducers can be concisely represented in Haskell, and demonstrate the benefits of utilising such an approach with a number of examples. In particular, tree transducers afford a modular programming style as they can be easily composed and manipulated. Our Haskell representation generalises the original...

  12. Crossflow force transducer

    International Nuclear Information System (INIS)

    Mulcahy, T.M.

    1982-05-01

    A force transducer for measuring lift and drag coefficients for a circular cylinder in turbulent water flow is presented. In addition to describing the actual design and construction of the strain-gauged force- ring based transducer, requirements for obtained valid fluid force test data are discussed, and pertinent flow test experience is related

  13. Modeling of ultrasound transducers

    DEFF Research Database (Denmark)

    Bæk, David

    This Ph.D. dissertation addresses ultrasound transducer modeling for medical ultrasound imaging and combines the modeling with the ultrasound simulation program Field II. The project firstly presents two new models for spatial impulse responses (SIR)s to a rectangular elevation focused transducer...... (REFT) and to a convex rectangular elevation focused transducer (CREFT). These models are solvable on an analog time scale and give exact smooth solutions to the Rayleigh integral. The REFT model exhibits a root mean square (RMS) error relative to Field II predictions of 0.41 % at 3400 MHz, and 1.......37 % at 100MHz. The CREFT model exhibits a RMS deviation of 0.01 % relative to the exact numerical solution on a CREFT transducer. A convex non-elevation focused, a REFT, and a linear flat transducer are shown to be covered with the CREFT model as well. Pressure pulses calculated with a one...

  14. FEATURES OF ELECTROMECHANICAL ACOUSTIC ENERGY CONVERSION BY CYLINDRICAL PIEZOCERAMIC TRANSDUCERS WITH INTERNAL SCREENS IN COMPOSITION OF FLAT SYSTEMS

    Directory of Open Access Journals (Sweden)

    A. G. Leiko

    2018-01-01

    Full Text Available The problem of sound emission is considered by a system formed from cylindrical piezoceramic radiators with internal acoustically soft screens. Longitudinal axis of emitters lie in one plane. This system is characterized by the interaction of electric, mechanical and acoustic fields in the process of conversion electrical energy to acoustical energy and acoustic fields in the process of forming them in the environments. The purpose of the work is to determine the peculiarities of the electromechanical acoustic transformation of energy by cylindrical piezoceramic radiators with internal screens in the composition of flat systems, taking into account all types of interaction.The research was carried out by the method of bound fields in multiply connected domains with the use of addition theorems for the cylindrical wave functions. The physical fields arising from the emission of sound by such a system are determined by the joint solution of the system of differential equations: the wave equation; equations of motion of thin piezoceramic shells with circular polarization in displacements; the equations of forced electrostatics for piezoceramics at given boundary conditions, the conditions of conjugation of fields at the boundaries of the division of domains and electric conditions.The solution of the problem is reduced to the solution of an infinite system of linear algebraic equations with respect to unknown coefficients of field expansions.An analysis of the results of numerical calculations, performed on the basis of the obtained analytical relations, called to establish a number of features in the electromechanical acoustic transformation of energy by emitters in the composition of flat systems. They include: the role of acoustic interaction in the process of energy conversion; determination of the mechanism of quantitative assessment of the influence of interaction on these processes; the dependence of the degree of violation of the radial

  15. From Bunsen Burners to Fuel Cells: Invoking Energy Transducers to Exemplify "Paths" and Unify the Energy-Related Concepts of Thermochemistry and Thermodynamics

    Science.gov (United States)

    Hladky, Paul W.

    2009-01-01

    The conversion of chemical energy entirely into thermal energy by Bunsen burners and into thermal energy and electrical energy by fuel cells of varying efficiencies illustrates different paths by which a chemical reaction can occur. Using the efficiency of producing electrical energy as a path label allows all of the energy-related quantities to…

  16. Structural differences of matrix metalloproteinases. Homology modeling and energy minimization of enzyme-substrate complexes

    DEFF Research Database (Denmark)

    Terp, G E; Christensen, I T; Jørgensen, Flemming Steen

    2000-01-01

    Matrix metalloproteinases are extracellular enzymes taking part in the remodeling of extracellular matrix. The structures of the catalytic domain of MMP1, MMP3, MMP7 and MMP8 are known, but structures of enzymes belonging to this family still remain to be determined. A general approach...... to the homology modeling of matrix metalloproteinases, exemplified by the modeling of MMP2, MMP9, MMP12 and MMP14 is described. The models were refined using an energy minimization procedure developed for matrix metalloproteinases. This procedure includes incorporation of parameters for zinc and calcium ions...... in the AMBER 4.1 force field, applying a non-bonded approach and a full ion charge representation. Energy minimization of the apoenzymes yielded structures with distorted active sites, while reliable three-dimensional structures of the enzymes containing a substrate in active site were obtained. The structural...

  17. Smart transducer with radiomodem

    Science.gov (United States)

    Pugach, V. N.; Voronin, E. L.

    2018-04-01

    Systems for measuring different parameters enabling metering and wireless data transmission are an urgent problem in the industry. One of the most promising solutions is the developments of metering instruments enabling radio-link and GSM data transmission. The article describes a transducer operating with temperature sensors of different types as well as with the sensors of other physical values with the output signal represented as current or voltage with subsequent measurement data transmission from the transducer to the computer via radio-link. The article provides transducer measurement accuracy check. The work confirmed the claimed temperature measurement accuracy, noted a stable data transmission via radio link and convenience of work with the transducer and software.

  18. A method for determining losses in magnetostrictive transducers

    Science.gov (United States)

    Krysin, V. N.; Ketlerov, A. S.

    A method for estimating energy losses in magnetostrictive transducers is described. It is shown that domain remagnetization is responsible for the greatest energy loss in magnetostrictive transducers. Energy losses associated with Foucault currents and Joule heat are an order of magnitude less.

  19. Corn and soybean meal metabolizable energy with the addition of exogenous enzymes for poultry

    Directory of Open Access Journals (Sweden)

    LRB Dourado

    2009-03-01

    Full Text Available Two metabolism assays were carried out to determine corn and soybean meal metabolizable energy when enzymes were added. In the first trial, 35 cockerels per studied feedstuff (corn and soybean meal were distributed in a completely randomized experimental design with four treatments of seven replicates of one bird each. The evaluated treatments were: ingredient (corn and soybean meal with no enzyme addition, with the addition of an enzyme complex (xylanase, amylase, protease - XAP, xylanase, or phytase. Precise feeding method was used to determine true metabolizable energy corrected for nitrogen balance (TMEn. The use of enzymes did not result in any differences (p>0.05 in soybean meal TMEn, but phytase improved corn TMEn in 2.3% (p=0.004. In the second trial, 280 seven-day-old broiler chicks were distributed in a completely randomized experimental design with seven treatments of five replicates of eight birds each. Treatments consisted of corn with no enzyme addition or with the addition of amylase, xylanase, phytase, XAP complex, XAP+phytase combination, or xylanase/ pectinase/β-glucanase complex (XPBG. Corn was supplemented with macro and trace minerals. Total excreta collection was used to determine apparent metabolizable energy corrected for nitrogen balance (AMEn. Differences were observed (p=0.08 in AMEn and dry matter metabolizability coefficient (p=0.03. The combination of the XAP complex with phytase promoted a 2.11% increase in corn AMEn values, and the remaining enzymes allowed increased between 0.86% and 1.66%.

  20. Immobilization of enzyme and antibody by low energy electron beam polymerization

    International Nuclear Information System (INIS)

    Kaetsu, Isao; Kumakura, Minoru

    1987-01-01

    Immobilization of glucoamylase and AFP-antibody was studied using an electron beam of relatively low energy. A thin polymer membrane formed by irradiation of monomer enzyme mixture in a buffer, which had a considerable enzymatic activity. A membrane of almost the same thickness and activity was obtained by repeated irradiation. The effect of irradiation conditions on the immobilization and the variations of irradiation method for immobilization were investigated. The immobilization of antibody was carried out in similar ways as for enzyme, and the product also showed a considerable activity. (author)

  1. Methods for Efficiently and Accurately Computing Quantum Mechanical Free Energies for Enzyme Catalysis.

    Science.gov (United States)

    Kearns, F L; Hudson, P S; Boresch, S; Woodcock, H L

    2016-01-01

    Enzyme activity is inherently linked to free energies of transition states, ligand binding, protonation/deprotonation, etc.; these free energies, and thus enzyme function, can be affected by residue mutations, allosterically induced conformational changes, and much more. Therefore, being able to predict free energies associated with enzymatic processes is critical to understanding and predicting their function. Free energy simulation (FES) has historically been a computational challenge as it requires both the accurate description of inter- and intramolecular interactions and adequate sampling of all relevant conformational degrees of freedom. The hybrid quantum mechanical molecular mechanical (QM/MM) framework is the current tool of choice when accurate computations of macromolecular systems are essential. Unfortunately, robust and efficient approaches that employ the high levels of computational theory needed to accurately describe many reactive processes (ie, ab initio, DFT), while also including explicit solvation effects and accounting for extensive conformational sampling are essentially nonexistent. In this chapter, we will give a brief overview of two recently developed methods that mitigate several major challenges associated with QM/MM FES: the QM non-Boltzmann Bennett's acceptance ratio method and the QM nonequilibrium work method. We will also describe usage of these methods to calculate free energies associated with (1) relative properties and (2) along reaction paths, using simple test cases with relevance to enzymes examples. © 2016 Elsevier Inc. All rights reserved.

  2. Calibration of acoustic emission transducers

    International Nuclear Information System (INIS)

    Leschek, W.C.

    1976-01-01

    A method is described for calibrating an acoustic emission transducer to be used in a pre-set frequency range. The absolute reception sensitivity of a reference transducer is determined at frequencies selected within the frequency range. The reference transducer and the acoustic emission transducer are put into acoustic communication with the surface of a limited acoustic medium representing an equivalent acoustic load appreciably identical to that of the medium in which the use of the acoustic emission transducer is intended. A blank random acoustic noise is emitted in the acoustic medium in order to establish a diffuse and reverberating sound field, after which the output responses of the reference transducer and of the acoustic emission transducer are obtained with respect to the diffuse and reverberating field, for selected frequencies. The output response of the acoustic emission transducer is compared with that of the reference transducer for the selected frequencies, so as to determine the reception sensitivity of the acoustic emission transducer [fr

  3. NMR signal transducer

    International Nuclear Information System (INIS)

    Kucheryaev, A.G.; Oliferchuk, N.L.

    1975-01-01

    A signal transducer of nuclear magnetic resonance for simultaneously measuring frequency and intensitivity of two various isotope signals, which are in one specimen is described. The transducer represents radiofrequency circuit with two resonance frequences, which is common for two autodyne generators. To decrease measuring time and to increase recording diagram stability the radiofrequency circuit has LC netork, in the inductivity of which investigated specimen is located; a circuit variable capacity is connected in parallel with one of the autodyne generators. Besides the radiofrequency circuit has an inductance coil in series with a standard specimen inside as well as a variable capacitor connected in parallel with the second autodyne generator. An amplitude of oscillation of each resonance frequency is controlled and adjusted separately. The transducer described can be used for the measurement of a nuclei concentration, isotope concentration and for the spin determination

  4. Enzyme Supplementation of Broiler Feeds with Reduced Mineral and Energy Levels

    Directory of Open Access Journals (Sweden)

    JO Nunes

    2015-12-01

    Full Text Available ABSTRACT An experiment was conducted with the purpose of evaluating enzyme blends on the performance, carcass traits, and bone mineralization of broilers. In total, 928 one-day-old Cobb 500 male chicks of were used. A completely randomized design with four treatments with eight replicates of 29 birds each was adopted. The evaluated treatments were: 1- Positive Control (PC, feed containing the nutritional recommendations of the genetic company's manual; 2- Negative Control (NC, feed with reductions of 75 kcal/kg AME and 0.10 and 0.12 percent points of phosphorus and calcium, respectively; 3 - NC + enzyme blend (amylase + b-glucanase, xylanase, and phytase; 250 g/t of feed and 4 - NC + enzyme complex (phytase, amylase, xylanase, glucanase, pectinase, cellulase, and protease; 200 g/t of feed. Birds fed the diet with reduced nutrient levels (NC presented the worst performance (p0.05 carcass or parts yields. The broilers fed the reduced-nutrient and energy diet presented lower (p<0.05 tibial ash, calcium, and phosphorus contents that the other treatments. The use of enzyme combinations improved the performance of broilers fed diets with reduced nutrient and energy levels.

  5. Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling.

    Science.gov (United States)

    Albaek, Mads O; Gernaey, Krist V; Hansen, Morten S; Stocks, Stuart M

    2012-04-01

    Modeling biotechnological processes is key to obtaining increased productivity and efficiency. Particularly crucial to successful modeling of such systems is the coupling of the physical transport phenomena and the biological activity in one model. We have applied a model for the expression of cellulosic enzymes by the filamentous fungus Trichoderma reesei and found excellent agreement with experimental data. The most influential factor was demonstrated to be viscosity and its influence on mass transfer. Not surprisingly, the biological model is also shown to have high influence on the model prediction. At different rates of agitation and aeration as well as headspace pressure, we can predict the energy efficiency of oxygen transfer, a key process parameter for economical production of industrial enzymes. An inverse relationship between the productivity and energy efficiency of the process was found. This modeling approach can be used by manufacturers to evaluate the enzyme fermentation process for a range of different process conditions with regard to energy efficiency. Copyright © 2011 Wiley Periodicals, Inc.

  6. Radiation-resistant pressure transducers

    International Nuclear Information System (INIS)

    Abbasov, Sh.M.; Kerimova, T.I.

    2005-01-01

    Full text : The sensitive element of vibrofrequency tensor converter (VTC) is an electromechanical resonator of string type with electrostatic excitation of longitudinal mechanical vibrations. The string is made from tensosensitive thread-like monocrystal n-Ge1-x Six (length 1-5 mm, diameter 8-12 mcm) with current outlet and strictly fixed by ends at plate or deformable surface (in elastic element) at 50 mcm apartheid. With increasing Si atomic percent in n-Ge1-x Six the converter tens sensitivity increases. There has been shown the scheme of pressure transducer which contains monocrystalline silicon membrane and string tens converter from thread-like monocrystal Ge-Si. Using method, when crystal position on membrane while it deforms by pressure, corresponds to free (uptight) state, allowed to obtain the maximum sensitivity in measurement of pressure fluctuation. The transducers of absolute and pressure differential of this type can be used in automated systems of life activity. The high sensitivity of string transducers to pressure exceeding 100 hertz/mm (water column) permits to use them in devices for measuring gas concentration. The combination of optical and deformation methods of measurements forms the basis of their operation. The pressure change occurs due to the fact that gas molecules absorbing the quanta of incident light, become at excited state and then excitation energy of their vibrational-rotatory degrees of freedom converts to the energy of translational motion of molecules, i.e. to heat appropriate to pressure increase. Using these tens converters of high pressure one can prevent the possible accidents on oil pipe-like Baku-Tibilisi-Ceyhan

  7. Piezoelectric transducer array microspeaker

    KAUST Repository

    Carreno, Armando Arpys Arevalo; Conchouso Gonzalez, David; Castro, David; Kosel, Jü rgen; Foulds, Ian G.

    2016-01-01

    contains 2n piezoelectric transducer membranes, where “n” is the bit number. Every element of the array has a circular shape structure. The membrane is made out four layers: 300nm of platinum for the bottom electrode, 250nm or lead zirconate titanate (PZT

  8. Vibration transducer calibration techniques

    Science.gov (United States)

    Brinkley, D. J.

    1980-09-01

    Techniques for the calibration of vibration transducers used in the Aeronautical Quality Assurance Directorate of the British Ministry of Defence are presented. Following a review of the types of measurements necessary in the calibration of vibration transducers, the performance requirements of vibration transducers, which can be used to measure acceleration, velocity or vibration amplitude, are discussed, with particular attention given to the piezoelectric accelerometer. Techniques for the accurate measurement of sinusoidal vibration amplitude in reference-grade transducers are then considered, including the use of a position sensitive photocell and the use of a Michelson laser interferometer. Means of comparing the output of working-grade accelerometers with that of previously calibrated reference-grade devices are then outlined, with attention given to a method employing a capacitance bridge technique and a method to be used at temperatures between -50 and 200 C. Automatic calibration procedures developed to speed up the calibration process are outlined, and future possible extensions of system software are indicated.

  9. Evaluation of the energy efficiency of enzyme fermentation by mechanistic modeling

    DEFF Research Database (Denmark)

    Albaek, Mads O.; Gernaey, Krist V.; Hansen, Morten S.

    2012-01-01

    Modeling biotechnological processes is key to obtaining increased productivity and efficiency. Particularly crucial to successful modeling of such systems is the coupling of the physical transport phenomena and the biological activity in one model. We have applied a model for the expression of ce...... was found. This modeling approach can be used by manufacturers to evaluate the enzyme fermentation process for a range of different process conditions with regard to energy efficiency.......Modeling biotechnological processes is key to obtaining increased productivity and efficiency. Particularly crucial to successful modeling of such systems is the coupling of the physical transport phenomena and the biological activity in one model. We have applied a model for the expression...... of cellulosic enzymes by the filamentous fungus Trichoderma reesei and found excellent agreement with experimental data. The most influential factor was demonstrated to be viscosity and its influence on mass transfer. Not surprisingly, the biological model is also shown to have high influence on the model...

  10. Nano-optomechanical transducer

    Science.gov (United States)

    Rakich, Peter T; El-Kady, Ihab F; Olsson, Roy H; Su, Mehmet Fatih; Reinke, Charles; Camacho, Ryan; Wang, Zheng; Davids, Paul

    2013-12-03

    A nano-optomechanical transducer provides ultrabroadband coherent optomechanical transduction based on Mach-wave emission that uses enhanced photon-phonon coupling efficiencies by low impedance effective phononic medium, both electrostriction and radiation pressure to boost and tailor optomechanical forces, and highly dispersive electromagnetic modes that amplify both electrostriction and radiation pressure. The optomechanical transducer provides a large operating bandwidth and high efficiency while simultaneously having a small size and minimal power consumption, enabling a host of transformative phonon and signal processing capabilities. These capabilities include optomechanical transduction via pulsed phonon emission and up-conversion, broadband stimulated phonon emission and amplification, picosecond pulsed phonon lasers, broadband phononic modulators, and ultrahigh bandwidth true time delay and signal processing technologies.

  11. High Temperature, High Power Piezoelectric Composite Transducers

    Science.gov (United States)

    Lee, Hyeong Jae; Zhang, Shujun; Bar-Cohen, Yoseph; Sherrit, StewarT.

    2014-01-01

    Piezoelectric composites are a class of functional materials consisting of piezoelectric active materials and non-piezoelectric passive polymers, mechanically attached together to form different connectivities. These composites have several advantages compared to conventional piezoelectric ceramics and polymers, including improved electromechanical properties, mechanical flexibility and the ability to tailor properties by using several different connectivity patterns. These advantages have led to the improvement of overall transducer performance, such as transducer sensitivity and bandwidth, resulting in rapid implementation of piezoelectric composites in medical imaging ultrasounds and other acoustic transducers. Recently, new piezoelectric composite transducers have been developed with optimized composite components that have improved thermal stability and mechanical quality factors, making them promising candidates for high temperature, high power transducer applications, such as therapeutic ultrasound, high power ultrasonic wirebonding, high temperature non-destructive testing, and downhole energy harvesting. This paper will present recent developments of piezoelectric composite technology for high temperature and high power applications. The concerns and limitations of using piezoelectric composites will also be discussed, and the expected future research directions will be outlined. PMID:25111242

  12. Molecular dynamics simulations and free energy calculations on the enzyme 4-hydroxyphenylpyruvate dioxygenase.

    Science.gov (United States)

    De Beer, Stephanie B A; Glättli, Alice; Hutzler, Johannes; Vermeulen, Nico P E; Oostenbrink, Chris

    2011-07-30

    4-Hydroxyphenylpyruvate dioxygenase is a relevant target in both pharmaceutical and agricultural research. We report on molecular dynamics simulations and free energy calculations on this enzyme, in complex with 12 inhibitors for which experimental affinities were determined. We applied the thermodynamic integration approach and the more efficient one-step perturbation. Even though simulations seem well converged and both methods show excellent agreement between them, the correlation with the experimental values remains poor. We investigate the effect of slight modifications on the charge distribution of these highly conjugated systems and find that accurate models can be obtained when using improved force field parameters. This study gives insight into the applicability of free energy methods and current limitations in force field parameterization. Copyright © 2011 Wiley Periodicals, Inc.

  13. Fluvoxamine alters the activity of energy metabolism enzymes in the brain

    Directory of Open Access Journals (Sweden)

    Gabriela K. Ferreira

    2014-09-01

    Full Text Available Objective: Several studies support the hypothesis that metabolism impairment is involved in the pathophysiology of depression and that some antidepressants act by modulating brain energy metabolism. Thus, we evaluated the activity of Krebs cycle enzymes, the mitochondrial respiratory chain, and creatine kinase in the brain of rats subjected to prolonged administration of fluvoxamine. Methods: Wistar rats received daily administration of fluvoxamine in saline (10, 30, and 60 mg/kg for 14 days. Twelve hours after the last administration, rats were killed by decapitation and the prefrontal cortex, cerebral cortex, hippocampus, striatum, and cerebellum were rapidly isolated. Results: The activities of citrate synthase, malate dehydrogenase, and complexes I, II-III, and IV were decreased after prolonged administration of fluvoxamine in rats. However, the activities of complex II, succinate dehydrogenase, and creatine kinase were increased. Conclusions: Alterations in activity of energy metabolism enzymes were observed in most brain areas analyzed. Thus, we suggest that the decrease in citrate synthase, malate dehydrogenase, and complexes I, II-III, and IV can be related to adverse effects of pharmacotherapy, but long-term molecular adaptations cannot be ruled out. In addition, we demonstrated that these changes varied according to brain structure or biochemical analysis and were not dose-dependent.

  14. Numerical Transducer Modeling

    DEFF Research Database (Denmark)

    Henriquez, Vicente Cutanda

    This thesis describes the development of a numerical model of the propagation of sound waves in fluids with viscous and thermal losses, with application to the simulation of acoustic transducers, in particular condenser microphones for measurement. The theoretical basis is presented, numerical...... manipulations are developed to satisfy the more complicated boundary conditions, and a model of a condenser microphone with a coupled membrane is developed. The model is tested against measurements of ¼ inch condenser microphones and analytical calculations. A detailed discussion of the results is given....

  15. Piezoelectric transducer array microspeaker

    KAUST Repository

    Carreno, Armando Arpys Arevalo

    2016-12-19

    In this paper we present the fabrication and characterization of a piezoelectric micro-speaker. The speaker is an array of micro-machined piezoelectric membranes, fabricated on silicon wafer using advanced micro-machining techniques. Each array contains 2n piezoelectric transducer membranes, where “n” is the bit number. Every element of the array has a circular shape structure. The membrane is made out four layers: 300nm of platinum for the bottom electrode, 250nm or lead zirconate titanate (PZT), a top electrode of 300nm and a structural layer of 50

  16. Standards for dielectric elastomer transducers

    International Nuclear Information System (INIS)

    Carpi, Federico; Frediani, Gabriele; Anderson, Iain; Bauer, Siegfried; Gallone, Giuseppe; Gei, Massimiliano; Graaf, Christian; Jean-Mistral, Claire; Kaal, William; Kofod, Guggi; Kollosche, Matthias; Kornbluh, Roy; Pelrine, Ron; Lassen, Benny; Rechenbach, Björn; Matysek, Marc; Michel, Silvain; Nowak, Stephan; O’Brien, Benjamin; Pei, Qibing

    2015-01-01

    Dielectric elastomer transducers consist of thin electrically insulating elastomeric membranes coated on both sides with compliant electrodes. They are a promising electromechanically active polymer technology that may be used for actuators, strain sensors, and electrical generators that harvest mechanical energy. The rapid development of this field calls for the first standards, collecting guidelines on how to assess and compare the performance of materials and devices. This paper addresses this need, presenting standardized methods for material characterisation, device testing and performance measurement. These proposed standards are intended to have a general scope and a broad applicability to different material types and device configurations. Nevertheless, they also intentionally exclude some aspects where knowledge and/or consensus in the literature were deemed to be insufficient. This is a sign of a young and vital field, whose research development is expected to benefit from this effort towards standardisation. (paper)

  17. Standards for dielectric elastomer transducers

    Science.gov (United States)

    Carpi, Federico; Anderson, Iain; Bauer, Siegfried; Frediani, Gabriele; Gallone, Giuseppe; Gei, Massimiliano; Graaf, Christian; Jean-Mistral, Claire; Kaal, William; Kofod, Guggi; Kollosche, Matthias; Kornbluh, Roy; Lassen, Benny; Matysek, Marc; Michel, Silvain; Nowak, Stephan; O'Brien, Benjamin; Pei, Qibing; Pelrine, Ron; Rechenbach, Björn; Rosset, Samuel; Shea, Herbert

    2015-10-01

    Dielectric elastomer transducers consist of thin electrically insulating elastomeric membranes coated on both sides with compliant electrodes. They are a promising electromechanically active polymer technology that may be used for actuators, strain sensors, and electrical generators that harvest mechanical energy. The rapid development of this field calls for the first standards, collecting guidelines on how to assess and compare the performance of materials and devices. This paper addresses this need, presenting standardized methods for material characterisation, device testing and performance measurement. These proposed standards are intended to have a general scope and a broad applicability to different material types and device configurations. Nevertheless, they also intentionally exclude some aspects where knowledge and/or consensus in the literature were deemed to be insufficient. This is a sign of a young and vital field, whose research development is expected to benefit from this effort towards standardisation.

  18. Enzymes of energy metabolism in hatchlings of amazonian freshwater turtles (Testudines, Podocnemididae

    Directory of Open Access Journals (Sweden)

    WP. Duncan

    Full Text Available The metabolic profiles of selected tissues were analyzed in hatchlings of the Amazonian freshwater turtles Podocnemis expansa, P. unifilis and P. sextuberculata. Metabolic design in these species was judged based on the key enzymes of energy metabolism, with special emphasis on carbohydrate, lipid, amino acid and ketone body metabolism. All species showed a high glycolytic potential in all sampled tissues. Based on low levels of hexokinase, glycogen may be an important fuel for these species. The high lactate dehydrogenase activity in the liver may play a significant role in carbohydrate catabolism, possibly during diving. Oxidative metabolism in P. sextuberculata appears to be designed for the use of lipids, amino acids and ketone bodies. The maximal activities of 3-hydroxyacyl-CoA dehydrogenase, malate dehydrogenase, glutamine dehydrogenase, alanine aminotransferase and succinyl-CoA keto transferase display high aerobic potential, especially in muscle and liver tissues of this species. Although amino acids and ketone bodies may be important fuels for oxidative metabolism, carbohydrates and lipids are the major fuels used by P. expansa and P. unifilis. Our results are consistent with the food habits and lifestyle of Amazonian freshwater turtles. The metabolic design, based on enzyme activities, suggests that hatchlings of P. unifilis and P. expansa are predominately herbivorous, whereas P. sextuberculata rely on a mixed diet of animal matter and vegetation.

  19. Study on electrical impedance matching for broadband ultrasonic transducer

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Geon Woo [University of Science and Technology, Daejeon (Korea, Republic of); Kim, Ki Bok [Korea Research Institute of Standards and Science, Center for Safety Measurement, Daejeon (Korea, Republic of); Baek, Kwang Sae [Elache Co., Busan (Korea, Republic of)

    2017-02-15

    Ultrasonic transducers with high resolution and resonant frequency are required to detect small defects (less than hundreds of μm) by ultrasonic testing. The resonance frequency and resolution of an ultrasonic transducer are closely related to the thickness of piezo-electric materials, backing materials, and the electric impedance matching technique. Among these factors, electrical impedance matching plays an important role because it can reduce the loss and reflection of ultrasonic energy differences in electrical impedance between an ultrasonic transducer and an ultrasonic defects detecting system. An LC matching circuit is the most frequently used electric matching method. It is necessary for the electrical impedance of an ultrasonic transducer to correspond to approximately 50 Ω to compensate the difference in electrical impedance between both connections. In this study, a 15 MHz immersion ultrasonic transducer was fabricated and an LC electrical impedance circuit was applied to that for having broad-band frequency characteristic.

  20. Biological energy from the igneous rock enhances cell growth and enzyme activity

    International Nuclear Information System (INIS)

    Lin Y.-L.; Kuo, H.-S; Chen, C.-T.; Kuo, S.-C.

    2000-01-01

    Some effects from natural resources might be ignored and unused by humans. Environmental hormesis could be a phenomena necessary to bio-organism existence on earth. Since 1919, radiation and some heavy metal hormesis from the environment were proved in various reports. In this study, igneous rock with very low radioactivity and high ferrous activity was measured by multichannel analyzer and inductively coupled plasma analyzer. The water treated by igneous rock, both directly soaked or indirectly in contact, induced increased activities of glucose oxidase, catalase, peroxidase, and superoxide dismutase. It also increased cell growth of SC-M1, HCT-15, Raji, and fibroblast cell lines. The water after treatment of igneous rock had no change in pH values, but displayed decreased conductivity values. We assume that the igneous rock could transfer energy to water to change the molecular structure or conformation of water cluster, or by radiation hormesis effect could then induce increased enzyme activity and cell growth. It is also possible that the energy from rock may combine radiation hormesis with other transferable biological energy forms to change water cluster conformation

  1. Circuit for Driving Piezoelectric Transducers

    Science.gov (United States)

    Randall, David P.; Chapsky, Jacob

    2009-01-01

    The figure schematically depicts an oscillator circuit for driving a piezoelectric transducer to excite vibrations in a mechanical structure. The circuit was designed and built to satisfy application-specific requirements to drive a selected one of 16 such transducers at a regulated amplitude and frequency chosen to optimize the amount of work performed by the transducer and to compensate for both (1) temporal variations of the resonance frequency and damping time of each transducer and (2) initially unknown differences among the resonance frequencies and damping times of different transducers. In other words, the circuit is designed to adjust itself to optimize the performance of whichever transducer is selected at any given time. The basic design concept may be adaptable to other applications that involve the use of piezoelectric transducers in ultrasonic cleaners and other apparatuses in which high-frequency mechanical drives are utilized. This circuit includes three resistor-capacitor networks that, together with the selected piezoelectric transducer, constitute a band-pass filter having a peak response at a frequency of about 2 kHz, which is approximately the resonance frequency of the piezoelectric transducers. Gain for generating oscillations is provided by a power hybrid operational amplifier (U1). A junction field-effect transistor (Q1) in combination with a resistor (R4) is used as a voltage-variable resistor to control the magnitude of the oscillation. The voltage-variable resistor is part of a feedback control loop: Part of the output of the oscillator is rectified and filtered for use as a slow negative feedback to the gate of Q1 to keep the output amplitude constant. The response of this control loop is much slower than 2 kHz and, therefore, does not introduce significant distortion of the oscillator output, which is a fairly clean sine wave. The positive AC feedback needed to sustain oscillations is derived from sampling the current through the

  2. Micromachined Integrated Transducers for Ultrasound Imaging

    DEFF Research Database (Denmark)

    la Cour, Mette Funding

    The purpose of this project is to develop capacitive micromachined ultrasonic transducers (CMUTs) for medical imaging. Medical ultrasound transducers used today are fabricated using piezoelectric materials and bulk processing. To fabricate transducers capable of delivering a higher imaging...

  3. Updated Results of Ultrasonic Transducer Irradiation Test

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua; Palmer, Joe [Idaho National Laboratory, P.O. Box 1625, MS 4112, Idaho Falls, ID, 38415-3840 (United States); Ramuhalli, Pradeep; Keller, Paul; Montgomery, Robert [Pacific Northwest National Laboratory, 902 Battelle Blvd. Richland, WA, 99354 (United States); Chien, Hual-Te [Argonne National Laboratory, 9700 S. Cass Avenue Argonne, IL, 60439 (United States); Tittmann, Bernhard; Reinhardt, Brian [Pennsylvania State University, 212 Earth and Engr. Sciences Building, University Park, PA, 16802 (United States); Kohse, Gordon [Massachusetts Institute of Technology, 77 Massachusetts Ave. Cambridge, MA 02139 (United States); Rempe, Joy [Rempe and Associates, LLC, 360 Stillwater, Idaho Falls, ID 83404 (United States); Villard, J.F. [Commissariat a l' energie atomique et aux energies alternatives, Centre d' etudes de Cadarache, 13108 Saint-Paul-lez-Durance (France)

    2015-07-01

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 10{sup 21} n/cm{sup 2}. A multi-National Laboratory collaboration funded by the Nuclear Energy Enabling Technologies Advanced Sensors and Instrumentation (NEET-ASI) program also provided initial support for this effort. This irradiation, which started in February 2014, is an instrumented lead test and real-time transducer performance data are collected along with temperature and neutron and gamma flux data. The irradiation is ongoing and will continue to approximately mid-2015. To date, very encouraging results have been attained as several transducers continue to operate under irradiation. (authors)

  4. [Effects of waterlogging on the growth and energy-metabolic enzyme activities of different tree species].

    Science.gov (United States)

    Wang, Gui-Bin; Cao, Fu-Liang; Zhang, Xiao-Yan; Zhang, Wang-Xiang

    2010-03-01

    Aimed to understand the waterlogging tolerance and adaptation mechanisms of different tree species, a simulated field experiment was conducted to study the growth and energy-metabolic enzyme activities of one-year-old seedlings of Taxodium distichum, Carya illinoensis, and Sapium sebiferum. Three treatments were installed, i. e., CK, waterlogging, and flooding, with the treatment duration being 60 days. Under waterlogging and flooding, the relative growth of test tree species was in the order of T. distichum > C. illinoensis > S. sebiferum, indicating that T. distichum had the strongest tolerance against waterlogging and flooding, while S. sebiferum had the weakest one. Also under waterlogging and flooding, the root/crown ratio of the three tree species increased significantly, suggesting that more photosynthates were allocated in roots, and the lactate dehydrogenase (LDH) and alcohol dehydrogenase (ADH) activities of the tree species also had a significant increase. Among the test tree species, T. distichum had the lowest increment of LDH and ADH activities under waterlogging and flooding, but the increment could maintain at a higher level in the treatment duration, while for C. illinoensis and S. sebiferum, the increment was larger during the initial and medium period, but declined rapidly during the later period of treatment. The malate dehydrogenase (MDH), phosphohexose (HPI), and glucose-6-phosphate dehydrogenase (G6PDH) -6-phosphogluconate dehydrogenase (6PGDH) activities of the tree species under waterlogging and flooding had a significant decrease, and the decrement was the largest for T. distichum, being 35.6% for MDH, 21.0% for HPI, and 22.7% for G6PDH - 6PGDH under flooding. It was suggested that under waterlogging and flooding, the tree species with strong waterlogging tolerance had a higher ability to maintain energy-metabolic balance, and thus, its growth could be maintained at a certain level.

  5. Piezoelectric Nanotube Array for Broadband High-Frequency Ultrasonic Transducer.

    Science.gov (United States)

    Liew, Weng Heng; Yao, Kui; Chen, Shuting; Tay, Francis Eng Hock

    2018-03-01

    Piezoelectric materials are vital in determining ultrasonic transducer and imaging performance as they offer the function for conversion between mechanical and electrical energy. Ultrasonic transducers with high-frequency operation suffer from performance degradation and fabrication difficulty of the demanded piezoelectric materials. Hence, we propose 1-D polymeric piezoelectric nanostructure with controlled nanoscale features to overcome the technical limitations of high-frequency ultrasonic transducers. For the first time, we demonstrate the integration of a well-aligned piezoelectric nanotube array to produce a high-frequency ultrasonic transducer with outstanding performance. We find that nanoconfinement-induced polarization orientation and unique nanotube structure lead to significantly improved piezoelectric and ultrasonic transducing performance over the conventional piezoelectric thin film. A large bandwidth, 126% (-6 dB), is achieved at high center frequency, 108 MHz. Transmission sensitivity of nanotube array is found to be 46% higher than that of the monolithic thin film transducer attributed to the improved electromechanical coupling effectiveness and impedance match. We further demonstrate high-resolution scanning, ultrasonic imaging, and photoacoustic imaging using the obtained nanotube array transducers, which is valuable for biomedical imaging applications in the future.

  6. The use of Fluorescence Resonance Energy Transfer (FRET peptidesfor measurement of clinically important proteolytic enzymes

    Directory of Open Access Journals (Sweden)

    Adriana K. Carmona

    2009-09-01

    Full Text Available Proteolytic enzymes have a fundamental role in many biological processes and are associated with multiple pathological conditions. Therefore, targeting these enzymes may be important for a better understanding of their function and development of therapeutic inhibitors. Fluorescence Resonance Energy Transfer (FRET peptides are convenient tools for the study of peptidases specificity as they allow monitoring of the reaction on a continuous basis, providing a rapid method for the determination of enzymatic activity. Hydrolysis of a peptide bond between the donor/acceptor pair generates fluorescence that permits the measurement of the activity of nanomolar concentrations of the enzyme. The assays can be performed directly in a cuvette of the fluorimeter or adapted for determinations in a 96-well fluorescence plate reader. The synthesis of FRET peptides containing ortho-aminobenzoic acid (Abz as fluorescent group and 2, 4-dinitrophenyl (Dnp or N-(2, 4-dinitrophenylethylenediamine (EDDnp as quencher was optimized by our group and became an important line of research at the Department of Biophysics of the Federal University of São Paulo. Recently, Abz/Dnp FRET peptide libraries were developed allowing high-throughput screening of peptidases substrate specificity. This review presents the consolidation of our research activities undertaken between 1993 and 2008 on the synthesis of peptides and study of peptidases specificities.As enzimas proteolíticas têm um papel fundamental em muitos processos biológicos e estão associadas a vários estados patológicos. Por isso, o estudo da especificidade das peptidases pode ser importante para uma melhor compreensão da função destas enzimas e para o desenvolvimento de inibidores. Os substratos com supressão intramolecular de fluorescência constituem uma excelente ferramenta, pois permitem o monitoramento da reação de forma contínua, proporcionando um método prático e rápido para a determinação da

  7. Characterization of Dielectric Electroactive Polymer transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Møller, Martin B.; Sarban, Rahimullah

    2014-01-01

    This paper analysis the small-signal model of the Dielectric Electro Active Polymer (DEAP) transducer. The DEAP transducer have been proposed as an alternative to the electrodynamic transducer in sound reproduction systems. In order to understand how the DEAP transducer works, and provide...

  8. Effects of Enzyme Treated Palm Kernel Expeller on Metabolizable Energy, Growth Performance, Villus Height and Digesta Viscosity in Broiler Chickens

    Directory of Open Access Journals (Sweden)

    P. Saenphoom

    2013-04-01

    Full Text Available This study examined whether pre-treating palm kernel expeller (PKE with exogenous enzyme would degrade its fiber content; thus improving its metabolizable energy (ME, growth performance, villus height and digesta viscosity in broiler chickens fed diets containing PKE. Our results showed that enzyme treatment decreased (p0.05 among treatment groups in the finisher period, ADG of chickens in the control (PKE-free diet was higher (p0.05 FCR. The intestinal villus height and crypt depth (duodenum, jejunum and ileum were not different (p>0.05 among treatments except for duodenal crypt depth. The villus height and crypt depth of birds in enzyme treated PKE diets were higher (p0.05 among treatments. Results of this study suggest that exogenous enzyme is effective in hydrolyzing the fiber (hemicellulose and cellulose component and improved the ME values of PKE, however, the above positive effects were not reflected in the growth performance in broiler chickens fed the enzyme treated PKE compared to those received raw PKE. The results suggest that PKE can be included up to 5% in the grower diet and 20% in the finisher diet without any significant negative effect on FCR in broiler chickens.

  9. Auto-positioning ultrasonic transducer system

    Science.gov (United States)

    Buchanan, Randy K. (Inventor)

    2010-01-01

    An ultrasonic transducer apparatus and process for determining the optimal transducer position for flow measurement along a conduit outer surface. The apparatus includes a transmitting transducer for transmitting an ultrasonic signal, said transducer affixed to a conduit outer surface; a guide rail attached to a receiving transducer for guiding movement of a receiving transducer along the conduit outer surface, wherein the receiving transducer receives an ultrasonic signal from the transmitting transducer and sends a signal to a data acquisition system; and a motor for moving the receiving transducer along the guide rail, wherein the motor is controlled by a controller. The method includes affixing a transmitting transducer to an outer surface of a conduit; moving a receiving transducer on the conduit outer surface, wherein the receiving transducer is moved along a guide rail by a motor; transmitting an ultrasonic signal from the transmitting transducer that is received by the receiving transducer; communicating the signal received by the receiving transducer to a data acquisition and control system; and repeating the moving, transmitting, and communicating along a length of the conduit.

  10. Enzymatic pretreatment of wood chips for energy reductions in TMP production. A method for ranking of enzymes; Enzymatisk foerbehandling av flis foer energibesparing vid TMP tillverkning. Metod foer rankning av enzymer

    Energy Technology Data Exchange (ETDEWEB)

    Viforr, Silvia

    2010-11-15

    The production of thermomechanical pulp (TMP) demands high levels of energy. This, together with current expensive energy prices of nowadays results in significant costs, which is the reason why there is a demand for processes that require less energy. One way of reducing energy consumption in TMP refining could be to pretreat the wood chips with enzymes before the subsequent refining step. However, enzymes molecules are relatively large, which limits the impregnation process, and so the pores in the fibre walls are not large enough to fit the size of the enzymes. By mechanically pretreating wood chips in a screw feeder and press equipment, this opens the wood structure significantly which increases enzyme penetration. If enzymes are used for reducing energy consumption in TMP processes, it is necessary to optimise the enzymatic effect during the pretreatment of wood chips. It is very expensive to evaluate completely the effect of enzymes in large scale refining. Thus there is a need for other relevant methods for rapidly and effectively evaluating the energy saving effects when it comes to refining enzymatic pretreated wood chips. The aim of this project was to find a method for ranking of enzymes for pretreatment of chips for energy savings at TMP production. This method was to be independent of the type of enzyme used and of the type of pretreated wood chips involved. In order to asses the method for ranking enzymes being used in the pretreatment of chips to reduce energy input during refining, a comparison between the method and a mill trial was carried out in the mill trial. A known chemical pretreatment was used; here it was sulphonation of the wood chips before refining with low sulphite levels. Further, a laboratory wing refiner was used as an evaluation equipment. The trial started with the running conditions for a wing refiner that the best correspond with industrial refining. An evaluation was made on the effect of enzymatic pretreatment on energy

  11. DEVELOPMENTAL STUDIES OF NUCLEAR DIGITAL TRANSDUCERS

    Energy Technology Data Exchange (ETDEWEB)

    Hyde, James L.

    1963-09-15

    A pressure transducer based on mechanical modulation of a beam of alpha particles is described. This type of transducer is capable of direct digital pressure measurexnent with corresponding telemetry advantages. Any variable that is sensed through a mechanical displacement is measurable by means of a corresponding member of this transducer family. Preliminary tests of an experimental pressure transducer show an overall accuracy within a few tenths of one percent, with promise of substantial improvement. General characteristics of nuclear digital transducers include exceptional long-term calibration stability and accuracy, independent of ambient environmental effects. Three concepts of systems enipioying these transducers are discussed. (auth)

  12. Acoustic Levitation With One Transducer

    Science.gov (United States)

    Barmatz, Martin B.

    1987-01-01

    Higher resonator modes enables simplification of equipment. Experimental acoustic levitator for high-temperature containerless processing has round cylindrical levitation chamber and only one acoustic transducer. Stable levitation of solid particle or liquid drop achieved by exciting sound in chamber to higher-order resonant mode that makes potential well for levitated particle or drop at some point within chamber.

  13. Proceedings of transducer 84 conference

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    In the broad and varied field of sensors this conference reviews thermal sensors for temperature measurements, gas sensors for gas analysis (for example analysis of exhaust gases from vehicles), optical fiber sensors, applications for optics, mechanics, robotics and signal processing. In particular one of the applications concerns acoustical transducers operating in liquid sodium for LMFBR reactors.

  14. Calculations for Piezoelectric Ultrasonic Transducers

    DEFF Research Database (Denmark)

    Jensen, Henrik

    1986-01-01

    Analysis of piezoelectric ultrasonic transducers implies a solution of a boundary value problem, for a boay which consists of different materials, including a piezoelectric part. The problem is dynamic at frequencies, where a typical wavelength is somewhat less than the size of the body. Radiation...

  15. [Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism].

    Science.gov (United States)

    Petrosyan, M S; Nersesova, L S; Gazaryants, M G; Meliksetyan, G O; Malakyan, M G; Bajinyan, S A; Akopian, J I

    2015-01-01

    The research deals with the effect of low-intensity 900 MHz frequency electromagnetic radiation (EMR), power density 25 μW/cm2, on the following rat brain and blood serum enzyme activities: creatine kinase (CK), playing a central role in the process of storing and distributing the cell energy, as well as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) that play a key role in providing the conjunction of carbohydrate and amino acid metabolism. The comparative analysis of the changes in the enzyme activity studied at different times following the two-hour single, as well as fractional, radiation equivalent of the total time showed that the most radiosensitive enzyme is the brain creatine kinase, which may then be recommended as a marker of the radio frequency radiation impact. According to the analysis of the changing dynamics of the CK, ALT and AST activity level, with time these changes acquire the adaptive character and are directed to compensate the damaged cell energy metabolism.

  16. The research on high power transducer

    International Nuclear Information System (INIS)

    Zhao Wuling; Li Yubin; Peng Shuwen

    2014-01-01

    This paper introduces the transducer structure used double PWM mode, the control system design of hardware and software. The transducer has been applied in factory. From the real experiment, it shows that the system has a high reliability. (authors)

  17. A Direct Driver for Electrostatic Transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    Electrostatic transducers represent a very interesting alternative to the traditional inefficient electrodynamic transducers. In order to establish the full potential of these transducers, power amplifiers which fulfill the strict requirements imposed by such loads (high impedance, frequency...... depended, nonlinear and high bias voltage for linearization) must be developed. This paper analyzes a power stage suitable for driving an electrostatic transducer under biasing. Measurement results of a ±400 V prototype amplifier are shown. THD below 1% is reported....

  18. Echo signal from rough planar interfaces influence of roughness, angle, range and transducer type

    DEFF Research Database (Denmark)

    Wilhjelm, Jens E.; Pedersen, P.C.; Jacobsen, S.M.

    1998-01-01

    The received electrical signal from a pulse-echo system insonifying a planar acoustical interface was measured for varying degrees of rms roughness (0-0.16 mm), angle of incidence (typically +/-7°) and range to the transducer. A planar and a focused 5 MHz transducer was used. When insonifying...... a smooth interface, the normalized spectrum of the received signals for a planar transducer exhibits an increasing number of nulls with increased angle of insonification, as predicted from numerical modeling while the dependence on insonification angle for the focused transducer was smaller and the null...... pattern was much less distinct. For the planar transducer and for the focused transducer with the interface located at the geometrical point of focus, the energy of the received signal as a function of incident angle was approximately Gaussian with maximum at 0°. For the smooth interface, the -3 dB width...

  19. Digital electrostatic acoustic transducer array

    KAUST Repository

    Carreno, Armando Arpys Arevalo

    2016-12-19

    In this paper we present the fabrication and characterization of an array of electrostatic acoustic transducers. The array is micromachined on a silicon wafer using standard micro-machining techniques. Each array contains 2n electrostatic transducer membranes, where “n” is the bit number. Every element of the array has a hexagonal membrane shape structure, which is separated from the substrate by 3µm air gap. The membrane is made out 5µm thick polyimide layer that has a bottom gold electrode on the substrate and a gold top electrode on top of the membrane (250nm). The wafer layout design was diced in nine chips with different array configurations, with variation of the membrane dimensions. The device was tested with 90 V giving and sound output level as high as 35dB, while actuating all the elements at the same time.

  20. Digital electrostatic acoustic transducer array

    KAUST Repository

    Carreno, Armando Arpys Arevalo; Castro, David; Conchouso Gonzalez, David; Kosel, Jü rgen; Foulds, Ian G.

    2016-01-01

    In this paper we present the fabrication and characterization of an array of electrostatic acoustic transducers. The array is micromachined on a silicon wafer using standard micro-machining techniques. Each array contains 2n electrostatic transducer membranes, where “n” is the bit number. Every element of the array has a hexagonal membrane shape structure, which is separated from the substrate by 3µm air gap. The membrane is made out 5µm thick polyimide layer that has a bottom gold electrode on the substrate and a gold top electrode on top of the membrane (250nm). The wafer layout design was diced in nine chips with different array configurations, with variation of the membrane dimensions. The device was tested with 90 V giving and sound output level as high as 35dB, while actuating all the elements at the same time.

  1. Construction and Experimental Implementation of a Model-Based Inverse Filter to Attenuate Hysteresis in Ferroelectric Transducers

    National Research Council Canada - National Science Library

    Hatch, Andrew G; Smith, Ralph C; De, Tathagata; Salapaka, Murti V

    2005-01-01

    .... In this paper, we illustrate the construction of inverse filters, based on homogenized energy models, which can be used to approximately linearize the piezoceramic transducer behavior for linear...

  2. Calculations for piezoelectric ultrasonic transducers

    International Nuclear Information System (INIS)

    Jensen, H.

    1986-05-01

    Analysis of piezoelectric ultrasonic transducers implies a solution of a boundary value problem, for a body which consists of different materials, including a piezoelectric part. The problem is dynamic at frequencies, where a typical wavelength is somewhat less than the size of the body. Radiation losses as well as internal losses may be important. Due to the complexity of the problem, a closed form solution is the exception rather than the rule. For this reason, it is necessary to use approximate methods for the analysis. Equivalent circuits, the Rayleigh-Ritz method, Mindlin plate theory and in particular the finite element method are considered. The finite element method is utilized for analysis of axisymmetric transducers. An explicit, fully piezoelectric, triangular ring element, with linear variations in displacement and electric potential is given. The influence of a fluid half-space is also given, in the form of a complex stiffness matrix. A special stacking procedure, for analysis of the backing has been developed. This procedure gives a saving, which is similar to that of the fast fourier transform algorithm, and is also wellsuited for analysis of finite and infinite waveguides. Results obtained by the finite element method are shown and compared with measurements and exact solutions. Good agreement is obtained. It is concluded that the finite element method can be a valueable tool in analysis and design of ultrasonic transducers. (author)

  3. Transducers

    Digital Repository Service at National Institute of Oceanography (India)

    Chakraborty, B

    stream_size 27 stream_content_type text/plain stream_name Encycl_Microcomputers_18_335.pdf.txt stream_source_info Encycl_Microcomputers_18_335.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset=ISO-8859-1 ...

  4. Consequences of lower food intake on the digestive enzymes activities, the energy reserves and the reproductive outcome in Gammarus fossarum.

    Directory of Open Access Journals (Sweden)

    Laetitia Charron

    Full Text Available Digestive enzyme activity is often used as a sensitive response to environmental pollution. However, only little is known about the negative effects of stress on digestive capacities and their consequences on energy reserves and reproduction, although these parameters are important for the maintenance of populations. To highlight if changes in biochemical responses (digestive enzymes and reserves led to impairments at an individual level (fertility, Gammarus fossarum were submitted to a lower food intake throughout a complete female reproductive cycle (i.e. from ovogenesis to offspring production. For both males and females, amylase activity was inhibited by the diet stress, whereas trypsin activity was not influenced. These results underline similar sensitivity of males and females concerning their digestive capacity. Energy reserves decreased with food starvation in females, and remained stable in males. The number of embryos per female decreased with food starvation. Lower digestive activity in males and females therefore appears as an early response. These results underline the ecological relevance of digestive markers, as they make it possible to anticipate upcoming consequences on reproduction in females, a key biological variable for population dynamics.

  5. Expression changes of hippocampal energy metabolism enzymes contribute to behavioural abnormalities during chronic morphine treatment

    Institute of Scientific and Technical Information of China (English)

    Xiao-Lan Chen; Jing-Gen Liu; Gang Lu; Ying-Xia Gong; Liang-Cai Zhao; Jie Chen; Zhi-Qiang Chi; Yi-Ming Yang; Zhong Chen; Qing-lin Li

    2007-01-01

    Dependence and impairment of learning and memory are two well-established features caused by abused drugs such as opioids. The hippocampus is an important region associated with both drug dependence and learning and memory. However, the molecular events in hippocampus following exposure to abused drugs such as opioids are not well understood. Here we examined the effect of chronic morphine treatment on hippocampal protein expression by proteomic analyses. We found that chronic exposure of mice to morphine for 10 days produced robust morphine withdrawal jumping and memory impairment, and also resulted in a significant downregulation of hippocampal protein levels of three metabolic enzymes, including Fe-S protein 1 of NADH dehydrogenase, dihydrolipoamide acetyltransferase or E2 component of the pyruvate dehydrogenase complex and lactate dehydrogenase 2. Further real-time quantitative PCR analyses confirmed that the levels of the corresponding mRNAs were also remarkably reduced. Consistent with these findings, lower ATP levels and an impaired ability to convert glucose into ATP were also observed in the hippocampus of chronically treated mice. Opioid antagonist naltrexone administrated concomitantly with morphine significantly suppressed morphine withdrawal jumping and reversed the downregulation of these proteins. Acute exposure to morphine also produced robust morphine withdrawal jumping and significant memory impairment, but failed to decrease the expression of these three proteins. Intrahippocampal injection of D-glucose before morphine administration significantly enhanced ATP levels and suppressed morphine withdrawal jumping and memory impairment in acute morphine-treated but not in chronic morphine-treated mice. Intraperitoneal injection of high dose of D-glucose shows a similar effect on morphine-induced withdrawal jumping as the central treatment. Taken together, our results suggest that reduced expression of the three metabolic enzymes in the hippocampus as

  6. Candle soot nanoparticles-polydimethylsiloxane composites for laser ultrasound transducers

    Science.gov (United States)

    Chang, Wei-Yi; Huang, Wenbin; Kim, Jinwook; Li, Sibo; Jiang, Xiaoning

    2015-10-01

    Generation of high power laser ultrasound strongly demands the advanced materials with efficient laser energy absorption, fast thermal diffusion, and large thermoelastic expansion capabilities. In this study, candle soot nanoparticles-polydimethylsiloxane (CSNPs-PDMS) composite was investigated as the functional layer for an optoacoustic transducer with high-energy conversion efficiency. The mean diameter of the collected candle soot carbon nanoparticles is about 45 nm, and the light absorption ratio at 532 nm wavelength is up to 96.24%. The prototyped CSNPs-PDMS nano-composite laser ultrasound transducer was characterized and compared with transducers using Cr-PDMS, carbon black (CB)-PDMS, and carbon nano-fiber (CNFs)-PDMS composites, respectively. Energy conversion coefficient and -6 dB frequency bandwidth of the CSNPs-PDMS composite laser ultrasound transducer were measured to be 4.41 × 10-3 and 21 MHz, respectively. The unprecedented laser ultrasound transduction performance using CSNPs-PDMS nano-composites is promising for a broad range of ultrasound therapy applications.

  7. Enzyme catalysis: a new definition accounting for noncovalent substrate- and product-like states.

    Science.gov (United States)

    Purich, D L

    2001-07-01

    Biological catalysis frequently causes changes in noncovalent bonding. By building on Pauling's assertion that any long-lived, chemically distinct interaction is a chemical bond, this article redefines enzyme catalysis as the facilitated making and/or breaking of chemical bonds, not just of covalent bonds. It is also argued that nearly every ATPase or GTPase is misnamed as a hydrolase and actually belongs to a distinct class of enzymes, termed here 'energases'. By transducing covalent bond energy into mechanical work, energases mediate such fundamental processes as protein folding, self-assembly, G-protein interactions, DNA replication, chromatin remodeling and even active transport.

  8. Tunable-angle wedge transducer for improved acoustophoretic control in a microfluidic chip

    DEFF Research Database (Denmark)

    Iranmanesh, I.; Barnkob, Rune; Bruus, Henrik

    2013-01-01

    We present a tunable-angle wedge ultrasound transducer for improved control of microparticle acoustophoresis in a microfluidic chip. The transducer is investigated by analyzing the pattern of aligned particles and induced acoustic energy density while varying the transducer geometry, transducer...... change in geometry and that the coupling angle may be used as an additional tuning parameter for improved acoustophoretic control with single-frequency actuation. Further, we find that frequency-modulation actuation is suitable for diminishing such tuning effects and that it is a robust method to produce...... coupling angle, and transducer actuation method (single-frequency actuation or frequency-modulation actuation). The energy-density analysis is based on measuring the transmitted light intensity through a microfluidic channel filled with a suspension of 5 µm diameter beads and the results with the tunable-angle...

  9. Micromachined capacitive ultrasonic immersion transducer array

    Science.gov (United States)

    Jin, Xuecheng

    Capacitive micromachined ultrasonic transducers (cMUTs) have emerged as an attractive alternative to conventional piezoelectric ultrasonic transducers. They offer performance advantages of wide bandwidth and sensitivity that have heretofore been attainable. In addition, micromachining technology, which has benefited from the fast-growing microelectronics industry, enables cMUT array fabrication and electronics integration. This thesis describes the design and fabrication of micromachined capacitive ultrasonic immersion transducer arrays. The basic transducer electrical equivalent circuit is derived from Mason's theory. The effects of Lamb waves and Stoneley waves on cross coupling and acoustic losses are discussed. Electrical parasitics such as series resistance and shunt capacitance are also included in the model of the transducer. Transducer fabrication technology is systematically studied. Device dimension control in both vertical and horizontal directions, process alternatives and variations in membrane formation, via etch and cavity sealing, and metalization as well as their impact on transducer performance are summarized. Both 64 and 128 element 1-D array transducers are fabricated. Transducers are characterized in terms of electrical input impedance, bandwidth, sensitivity, dynamic range, impulse response and angular response, and their performance is compared with theoretical simulation. Various schemes for cross coupling reduction is analyzed, implemented, and verified with both experiments and theory. Preliminary results of immersion imaging are presented using 64 elements 1-D array transducers for active source imaging.

  10. LAVA Pressure Transducer Trade Study

    Science.gov (United States)

    Oltman, Samuel B.

    2016-01-01

    The Regolith and Environment Science and Oxygen and Lunar Volatile Extraction (RESOLVE) payload will transport the (LAVA) subsystem to hydrogen-rich locations on the moon supporting NASA's in-situ resource utilization (ISRU) programs. There, the LAVA subsystem will analyze volatiles that evolve from heated regolith samples in order to quantify how much water is present. To do this, the system needs resilient pressure transducers (PTs) to calculate the moles in the gas samples. The PT trade study includes a comparison of newly-procured models to a baseline unit with prior flight history in order to determine the PT model with the best survivability in flight-forward conditions.

  11. Na,K-ATPase biostimulation by low-energy laser irradiation: comparative effects in membrane, solubilized and proteoliposomes enzyme

    Energy Technology Data Exchange (ETDEWEB)

    Rigos, C.F.; Tedesco, A.C.; Ciancaglini, P. [Universidade de Sao Paulo (USP), Ribeirao Preto, SP (Brazil). Faculdade de Filosofia, Ciencias e Letras. Dept. de Quimica; Santos, H.L. [Universidade Federal de Sao Joao Del Rei (UFSJ), MG (Brazil)

    2008-07-01

    Full text: The mechanism of laser irradiation action on living cells is not yet understood. The role of membrane ATPases as possible targets has been analyzed. In our group we have been working with Na,K-ATPase. This enzyme is a member of the P-type family of active cation transport proteins. Thus, the aim of the present work was to investigate the effect of low-energy laser irradiation (685 nm, 35 mW) on the ATPase activity of different forms of the Na,K-ATPase. Membrane-bound and solubilized (ab)2 form of Na,K-ATPase was obtained from the rabbit kidney and DPPC:DPPE-proteoliposomes were prepared by the co-solubilization method. Irradiations were carried out at 685 nm. The ATPase activity of the membrane fraction was not altered with exposition to irradiation doses between 4 and 24 J/c m2. With irradiation doses ranging from 32 to 40 J/c m2, a 28% increase on the ATPase activity was observed while when using up to 50 J/c m2 no additional enhancement was observed. When bio stimulation was done using the purified or the reconstituted enzyme, an increase of about 36-40% on the ATPase activity was observed using only 4-8 J/c m2. With irradiation above these values (24 J/c m2) no additional increase in the activity appeared. These studies revealed that the bio stimulation of ATPase activity from different forms of the Na,K -ATPase is dose dependent in different ranges of irradiation exposure. The stimulation promoted by visible laser doses was modulated and the process was reverted after 2 h for the enzyme present in the membrane and after about 5 h for the solubilized or the reconstituted in DPPC:DPPE-liposomes.

  12. Na,K-ATPase biostimulation by low-energy laser irradiation: comparative effects in membrane, solubilized and proteoliposomes enzyme

    International Nuclear Information System (INIS)

    Rigos, C.F.; Tedesco, A.C.; Ciancaglini, P.

    2008-01-01

    Full text: The mechanism of laser irradiation action on living cells is not yet understood. The role of membrane ATPases as possible targets has been analyzed. In our group we have been working with Na,K-ATPase. This enzyme is a member of the P-type family of active cation transport proteins. Thus, the aim of the present work was to investigate the effect of low-energy laser irradiation (685 nm, 35 mW) on the ATPase activity of different forms of the Na,K-ATPase. Membrane-bound and solubilized (ab)2 form of Na,K-ATPase was obtained from the rabbit kidney and DPPC:DPPE-proteoliposomes were prepared by the co-solubilization method. Irradiations were carried out at 685 nm. The ATPase activity of the membrane fraction was not altered with exposition to irradiation doses between 4 and 24 J/c m2. With irradiation doses ranging from 32 to 40 J/c m2, a 28% increase on the ATPase activity was observed while when using up to 50 J/c m2 no additional enhancement was observed. When bio stimulation was done using the purified or the reconstituted enzyme, an increase of about 36-40% on the ATPase activity was observed using only 4-8 J/c m2. With irradiation above these values (24 J/c m2) no additional increase in the activity appeared. These studies revealed that the bio stimulation of ATPase activity from different forms of the Na,K -ATPase is dose dependent in different ranges of irradiation exposure. The stimulation promoted by visible laser doses was modulated and the process was reverted after 2 h for the enzyme present in the membrane and after about 5 h for the solubilized or the reconstituted in DPPC:DPPE-liposomes

  13. A new ultrasonic transducer for improved contrast nonlinear imaging

    International Nuclear Information System (INIS)

    Bouakaz, Ayache; Cate, Folkert ten; Jong, Nico de

    2004-01-01

    Second harmonic imaging has provided significant improvement in contrast detection over fundamental imaging. This improvement is a result of a higher contrast-to-tissue ratio (CTR) achievable at the second harmonic frequency. Nevertheless, the differentiation between contrast and tissue at the second harmonic frequency is still in many situations cumbersome and contrast detection remains nowadays as one of the main challenges, especially in the capillaries. The reduced CTR is mainly caused by the generation of second harmonic energy from nonlinear propagation effects in tissue, which hence obscures the echoes from contrast bubbles. In a previous study, we demonstrated theoretically that the CTR increases with the harmonic number. Therefore the purpose of our study was to increase the CTR by selectively looking to the higher harmonic frequencies. In order to be able to receive these high frequency components (third up to the fifth harmonic), a new ultrasonic phased array transducer has been constructed. The main advantage of the new design is its wide frequency bandwidth. The new array transducer contains two different types of elements arranged in an interleaved pattern (odd and even elements). This design enables separate transmission and reception modes. The odd elements operate at 2.8 MHz and 80% bandwidth, whereas the even elements have a centre frequency of 900 kHz with a bandwidth of 50%. The probe is connected to a Vivid 5 system (GE-Vingmed) and proper software is developed for driving. The total bandwidth of such a transducer is estimated to be more than 150% which enables higher harmonic imaging at an adequate sensitivity and signal to noise ratio compared to standard medical array transducers. We describe in this paper the design and fabrication of the array transducer. Moreover its acoustic properties are measured and its performances for nonlinear contrast imaging are evaluated in vitro and in vivo. The preliminary results demonstrate the advantages of

  14. Micromachined Ultrasonic Transducers for 3-D Imaging

    DEFF Research Database (Denmark)

    Christiansen, Thomas Lehrmann

    of state-of-the-art 3-D ultrasound systems. The focus is on row-column addressed transducer arrays. This previously sparsely investigated addressing scheme offers a highly reduced number of transducer elements, resulting in reduced transducer manufacturing costs and data processing. To produce...... such transducer arrays, capacitive micromachined ultrasonic transducer (CMUT) technology is chosen for this project. Properties such as high bandwidth and high design flexibility makes this an attractive transducer technology, which is under continuous development in the research community. A theoretical...... treatment of CMUTs is presented, including investigations of the anisotropic plate behaviour and modal radiation patterns of such devices. Several new CMUT fabrication approaches are developed and investigated in terms of oxide quality and surface protrusions, culminating in a simple four-mask process...

  15. The Dynamic Performance of Flexural Ultrasonic Transducers

    Directory of Open Access Journals (Sweden)

    Andrew Feeney

    2018-01-01

    Full Text Available Flexural ultrasonic transducers are principally used as proximity sensors and for industrial metrology. Their operation relies on a piezoelectric ceramic to generate a flexing of a metallic membrane, which delivers the ultrasound signal. The performance of flexural ultrasonic transducers has been largely limited to excitation through a short voltage burst signal at a designated mechanical resonance frequency. However, a steady-state amplitude response is not generated instantaneously in a flexural ultrasonic transducer from a drive excitation signal, and differences in the drive characteristics between transmitting and receiving transducers can affect the measured response. This research investigates the dynamic performance of flexural ultrasonic transducers using acoustic microphone measurements and laser Doppler vibrometry, supported by a detailed mechanical analog model, in a process which has not before been applied to the flexural ultrasonic transducer. These techniques are employed to gain insights into the physics of their vibration behaviour, vital for the optimisation of industrial ultrasound systems.

  16. Transducers and arrays for underwater sound

    CERN Document Server

    Butler, John L

    2016-01-01

    This improved and updated second edition covers the theory, development, and design of electro-acoustic transducers for underwater applications. This highly regarded text discusses the basics of piezoelectric and magnetostrictive transducers that are currently being used as well as promising new designs. It presents the basic acoustics as well as the specific acoustics data needed in transducer design and evaluation. A broad range of designs of projectors and hydrophones are described in detail along with methods of modeling, evaluation, and measurement. Analysis of projector and hydrophone transducer arrays, including the effects of mutual radiation impedance and numerical models for elements and arrays, are also covered. The book includes new advances in transducer design and transducer materials and has been completely reorganized to be suitable for use as a textbook, as well as a reference or handbook. The new edition contains updates to the first edition, end-of-chapter exercises, and solutions to select...

  17. Nuclear Radiation Tolerance of Single Crystal Aluminum Nitride Ultrasonic Transducer

    Science.gov (United States)

    Reinhard, Brian; Tittmann, Bernhard R.; Suprock, Andrew

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models, (Rempe et al., 2011; Kazys et al., 2005). These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 1021 n/cm2. The irradiation is also supported by a multi-National Laboratory collaboration funded by the Nuclear Energy Enabling Technologies Advanced Sensors and Instrumentation (NEET ASI) program. The results from this irradiation, which started in February 2014, offer the potential to enable the development of novel radiation tolerant ultrasonic sensors for use in Material Testing Reactors (MTRs). As such, this test is an instrumented lead test and real-time transducer performance data is collected along with temperature and neutron and gamma flux data. Hence, results from this irradiation offer the potential to bridge the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the

  18. A photocatalyst-enzyme coupled artificial photosynthesis system for solar energy in production of formic acid from CO2.

    Science.gov (United States)

    Yadav, Rajesh K; Baeg, Jin-Ook; Oh, Gyu Hwan; Park, No-Joong; Kong, Ki-jeong; Kim, Jinheung; Hwang, Dong Won; Biswas, Soumya K

    2012-07-18

    The photocatalyst-enzyme coupled system for artificial photosynthesis process is one of the most promising methods of solar energy conversion for the synthesis of organic chemicals or fuel. Here we report the synthesis of a novel graphene-based visible light active photocatalyst which covalently bonded the chromophore, such as multianthraquinone substituted porphyrin with the chemically converted graphene as a photocatalyst of the artificial photosynthesis system for an efficient photosynthetic production of formic acid from CO(2). The results not only show a benchmark example of the graphene-based material used as a photocatalyst in general artificial photosynthesis but also the benchmark example of the selective production system of solar chemicals/solar fuel directly from CO(2).

  19. Microbial surface displayed enzymes based biofuel cell utilizing degradation products of lignocellulosic biomass for direct electrical energy.

    Science.gov (United States)

    Fan, Shuqin; Hou, Chuantao; Liang, Bo; Feng, Ruirui; Liu, Aihua

    2015-09-01

    In this work, a bacterial surface displaying enzyme based two-compartment biofuel cell for the direct electrical energy conversion from degradation products of lignocellulosic biomass is reported. Considering that the main degradation products of the lignocellulose are glucose and xylose, xylose dehydrogenase (XDH) displayed bacteria (XDH-bacteria) and glucose dehydrogenase (GDH) displayed bacteria (GDH-bacteria) were used as anode catalysts in anode chamber with methylene blue as electron transfer mediator. While the cathode chamber was constructed with laccase/multi-walled-carbon nanotube/glassy-carbon-electrode. XDH-bacteria exhibited 1.75 times higher catalytic efficiency than GDH-bacteria. This assembled enzymatic fuel cell exhibited a high open-circuit potential of 0.80 V, acceptable stability and energy conversion efficiency. Moreover, the maximum power density of the cell could reach 53 μW cm(-2) when fueled with degradation products of corn stalk. Thus, this finding holds great potential to directly convert degradation products of biomass into electrical energy. Copyright © 2015 Elsevier Ltd. All rights reserved.

  20. Note: Decoupling design for high frequency piezoelectric ultrasonic transducers with their clamping connections

    Energy Technology Data Exchange (ETDEWEB)

    Wang, F. J., E-mail: wangfujun@tju.edu.cn; Liang, C. M.; Tian, Y. L.; Zhao, X. Y.; Zhang, D. W. [Tianjin Key Laboratory of Equipment Design and Manufacturing Technology, School of Mechanical Engineering, Tianjin University, Tianjin 300072 (China); Zhang, H. J. [Tianjin Key Laboratory of Modern Mechatronics Equipment Technology, School of Mechanical Engineering, Tianjin Polytechnic University, Tianjin 300387 (China)

    2015-12-15

    This work presents the flexure-mechanism based decoupling design between high frequency piezoelectric ultrasonic transducers and their clamping connections to improve ultrasonic energy transmission efficiency. The ring, prismatic beam, and circular notched hinge based flanges were presented, and the crucial geometric dimensions of the transducers with the flexure decoupling flanges were determined. Finite element analysis (FEA) was carried out to investigate the dynamic characteristics of the transducers. Finally, experiments were conducted to examine and verify the effects of the proposed decoupling flanges. FEA and experimental results show that smaller frequency deviations and larger tip displacement amplitudes have been achieved by using the transducers with the flexure flanges compared with the transducer with a rigid ring-type flange, and thus the ultrasonic transmission efficiency can be improved through the flexure flanges.

  1. Integration of biomolecular logic gates with field-effect transducers

    Energy Technology Data Exchange (ETDEWEB)

    Poghossian, A., E-mail: a.poghossian@fz-juelich.de [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany); Malzahn, K. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Abouzar, M.H. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany); Mehndiratta, P. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Katz, E. [Department of Chemistry and Biomolecular Science, NanoBio Laboratory (NABLAB), Clarkson University, Potsdam, NY 13699-5810 (United States); Schoening, M.J. [Institute of Nano- and Biotechnologies, Aachen University of Applied Sciences, Campus Juelich, Heinrich-Mussmann-Str. 1, D-52428 Juelich (Germany); Institute of Bio- and Nanosystems, Research Centre Juelich GmbH, D-52425 Juelich (Germany)

    2011-11-01

    Highlights: > Enzyme-based AND/OR logic gates are integrated with a capacitive field-effect sensor. > The AND/OR logic gates compose of multi-enzyme system immobilised on sensor surface. > Logic gates were activated by different combinations of chemical inputs (analytes). > The logic output (pH change) produced by the enzymes was read out by the sensor. - Abstract: The integration of biomolecular logic gates with field-effect devices - the basic element of conventional electronic logic gates and computing - is one of the most attractive and promising approaches for the transformation of biomolecular logic principles into macroscopically useable electrical output signals. In this work, capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensors based on a p-Si-SiO{sub 2}-Ta{sub 2}O{sub 5} structure modified with a multi-enzyme membrane have been used for electronic transduction of biochemical signals processed by enzyme-based OR and AND logic gates. The realised OR logic gate composes of two enzymes (glucose oxidase and esterase) and was activated by ethyl butyrate or/and glucose. The AND logic gate composes of three enzymes (invertase, mutarotase and glucose oxidase) and was activated by two chemical input signals: sucrose and dissolved oxygen. The developed integrated enzyme logic gates produce local pH changes at the EIS sensor surface as a result of biochemical reactions activated by different combinations of chemical input signals, while the pH value of the bulk solution remains unchanged. The pH-induced charge changes at the gate-insulator (Ta{sub 2}O{sub 5}) surface of the EIS transducer result in an electronic signal corresponding to the logic output produced by the immobilised enzymes. The logic output signals have been read out by means of a constant-capacitance method.

  2. Integration of biomolecular logic gates with field-effect transducers

    International Nuclear Information System (INIS)

    Poghossian, A.; Malzahn, K.; Abouzar, M.H.; Mehndiratta, P.; Katz, E.; Schoening, M.J.

    2011-01-01

    Highlights: → Enzyme-based AND/OR logic gates are integrated with a capacitive field-effect sensor. → The AND/OR logic gates compose of multi-enzyme system immobilised on sensor surface. → Logic gates were activated by different combinations of chemical inputs (analytes). → The logic output (pH change) produced by the enzymes was read out by the sensor. - Abstract: The integration of biomolecular logic gates with field-effect devices - the basic element of conventional electronic logic gates and computing - is one of the most attractive and promising approaches for the transformation of biomolecular logic principles into macroscopically useable electrical output signals. In this work, capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensors based on a p-Si-SiO 2 -Ta 2 O 5 structure modified with a multi-enzyme membrane have been used for electronic transduction of biochemical signals processed by enzyme-based OR and AND logic gates. The realised OR logic gate composes of two enzymes (glucose oxidase and esterase) and was activated by ethyl butyrate or/and glucose. The AND logic gate composes of three enzymes (invertase, mutarotase and glucose oxidase) and was activated by two chemical input signals: sucrose and dissolved oxygen. The developed integrated enzyme logic gates produce local pH changes at the EIS sensor surface as a result of biochemical reactions activated by different combinations of chemical input signals, while the pH value of the bulk solution remains unchanged. The pH-induced charge changes at the gate-insulator (Ta 2 O 5 ) surface of the EIS transducer result in an electronic signal corresponding to the logic output produced by the immobilised enzymes. The logic output signals have been read out by means of a constant-capacitance method.

  3. A capacitive ultrasonic transducer based on parametric resonance.

    Science.gov (United States)

    Surappa, Sushruta; Satir, Sarp; Levent Degertekin, F

    2017-07-24

    A capacitive ultrasonic transducer based on a parametric resonator structure is described and experimentally demonstrated. The transducer structure, which we call capacitive parametric ultrasonic transducer (CPUT), uses a parallel plate capacitor with a movable membrane as part of a degenerate parametric series RLC resonator circuit with a resonance frequency of f o . When the capacitor plate is driven with an incident harmonic ultrasonic wave at the pump frequency of 2f o with sufficient amplitude, the RLC circuit becomes unstable and ultrasonic energy can be efficiently converted to an electrical signal at f o frequency in the RLC circuit. An important characteristic of the CPUT is that unlike other electrostatic transducers, it does not require DC bias or permanent charging to be used as a receiver. We describe the operation of the CPUT using an analytical model and numerical simulations, which shows drive amplitude dependent operation regimes including parametric resonance when a certain threshold is exceeded. We verify these predictions by experiments with a micromachined membrane based capacitor structure in immersion where ultrasonic waves incident at 4.28 MHz parametrically drive a signal with significant amplitude in the 2.14 MHz RLC circuit. With its unique features, the CPUT can be particularly advantageous for applications such as wireless power transfer for biomedical implants and acoustic sensing.

  4. A capacitive ultrasonic transducer based on parametric resonance

    Science.gov (United States)

    Surappa, Sushruta; Satir, Sarp; Levent Degertekin, F.

    2017-07-01

    A capacitive ultrasonic transducer based on a parametric resonator structure is described and experimentally demonstrated. The transducer structure, which we call capacitive parametric ultrasonic transducer (CPUT), uses a parallel plate capacitor with a movable membrane as part of a degenerate parametric series RLC resonator circuit with a resonance frequency of fo. When the capacitor plate is driven with an incident harmonic ultrasonic wave at the pump frequency of 2fo with sufficient amplitude, the RLC circuit becomes unstable and ultrasonic energy can be efficiently converted to an electrical signal at fo frequency in the RLC circuit. An important characteristic of the CPUT is that unlike other electrostatic transducers, it does not require DC bias or permanent charging to be used as a receiver. We describe the operation of the CPUT using an analytical model and numerical simulations, which shows drive amplitude dependent operation regimes including parametric resonance when a certain threshold is exceeded. We verify these predictions by experiments with a micromachined membrane based capacitor structure in immersion where ultrasonic waves incident at 4.28 MHz parametrically drive a signal with significant amplitude in the 2.14 MHz RLC circuit. With its unique features, the CPUT can be particularly advantageous for applications such as wireless power transfer for biomedical implants and acoustic sensing.

  5. A new high performance current transducer

    International Nuclear Information System (INIS)

    Tang Lijun; Lu Songlin; Li Deming

    2003-01-01

    A DC-100 kHz current transducer is developed using a new technique on zero-flux detecting principle. It was shown that the new current transducer is of high performance, its magnetic core need not be selected very stringently, and it is easy to manufacture

  6. Cobalt deficiency effects on trace elements, hormones and enzymes involved in energy metabolism of cattle.

    Science.gov (United States)

    Stangl, G I; Schwarz, F J; Kirchgessner, M

    1999-03-01

    This study was conducted to investigate the physiological consequences of long-term moderate cobalt deficiency in beef cattle, which have not hitherto been studied in detail. Cobalt deficiency was induced in cattle by feeding two groups of animals either a basal corn silage-based diet that was moderately low in cobalt (83 micrograms Co/kg), or the same diet supplemented with cobalt to a total of 200 micrograms per kg, for 43 weeks. Cobalt deficiency was induced, as judged by inappetance, diminished growth gain and a markedly reduced vitamin B12 status in serum and liver. The long-term cobalt deprivation which was primarily a combination of reduced feed intake and a tissue vitamin B12 deficiency did not show evidence of a significant dysfunction of energy metabolism. The activities of glucose-6-phosphate dehydrogenase and cytochrome oxidase in liver remained unaffected by cobalt deficiency, nor was there a significant change in serum glucose level of cattle on the cobalt-deprived diet. However, analysis of thyroid hormone status indicated a slight reduction of type I thyroxine monodeiodinase activity in liver accompanied by a significant reduction of the triiodothyronine level in serum. The diminished liver vitamin B12 level resulted in significantly reduced folate level in this tissue, reduced concentrations of heme-depending blood parameters. Moreover cobalt deficiency or rather vitamin B12 deficiency was accompanied by a dramatic accumulation of the trace elements iron and nickel in liver. These results indicate that long-term moderate cobalt deficiency may induce a number of physiological changes in cattle, but a follow-up study, which excluded different feed levels by including a pair-fed control group, will be necessary to actually obtain the single effect of cobalt deficiency in cattle.

  7. Advanced Low Energy Enzyme Catalyzed Solvent for CO2 Capture

    Energy Technology Data Exchange (ETDEWEB)

    Zaks, Alex [Akermin Inc., St. Louis, MO (United States); Reardon, John [Akermin Inc., St. Louis, MO (United States)

    2013-09-30

    A proof-of-concept biocatalyst enhanced solvent process was developed and demonstrated in an integrated bench-scale system using coal post combustion flue gas. The biocatalyst was deployed as a coating on M500X structured packing. Rate enhancement was evaluated using a non-volatile and non-toxic 20 wt% potassium carbonate solution. Greater than 500-fold volumetric scale-up from laboratory to bench scale was demonstrated in this project. Key technical achievements included: 10-fold mass transfer enhancement demonstrated in laboratory testing relative to blank potassium carbonate at 45°C; ~ 7-fold enhancement over blank in bench-scale field testing at National Carbon Capture Center; aerosol emissions were below detection limits (< 0.8 ppm); 90% capture was demonstrated at ~19.5 Nm3/hr (dry basis); and ~ 80% CO2 capture was demonstrated at ~ 30 Nm3/hr (dry basis) for more than 2800-hrs on flue gas with minimal detectible decline in activity. The regeneration energy requirement was 3.5 GJ/t CO2 for this solvent, which was below the target of <2.1 GJ/t CO2. Bench unit testing revealed kinetic limitations in the un-catalyzed stripper at around 85°C, but process modeling based on bench unit data showed that equivalent work of less than 300 kWh/t CO2 including all CO2 compression can be achieved at lower temperature stripping conditions. Cost analysis showed that 20% potassium carbonate in a basic solvent flow sheet with biocatalyst coated packing has economic performance comparable to the reference NETL Case-12, 30% MEA. A detailed techno-economic analysis indicated that addition of catalyst in the stripper could reduce the cost of capture by ~6% and cost of avoided CO2 by ~10% below reference NETL Case-12. Based on these results, a directional plan was identified to reduce the cost of CO2 capture in future work.

  8. Using Portable Transducers to Measure Tremor Severity

    Directory of Open Access Journals (Sweden)

    Rodger Elble

    2016-05-01

    Full Text Available Background: Portable motion transducers, suitable for measuring tremor, are now available at a reasonable cost. The use of these transducers requires knowledge of their limitations and data analysis. The purpose of this review is to provide a practical overview and example software for using portable motion transducers in the quantification of tremor. Methods: Medline was searched via PubMed.gov in December 2015 using the Boolean expression “tremor AND (accelerometer OR accelerometry OR gyroscope OR inertial measurement unit OR digitizing tablet OR transducer.” Abstracts of 419 papers dating back to 1964 were reviewed for relevant portable transducers and methods of tremor analysis, and 105 papers written in English were reviewed in detail. Results: Accelerometers, gyroscopes, and digitizing tablets are used most commonly, but few are sold for the purpose of measuring tremor. Consequently, most software for tremor analysis is developed by the user. Wearable transducers are capable of recording tremor continuously, in the absence of a clinician. Tremor amplitude, frequency, and occurrence (percentage of time with tremor can be computed. Tremor amplitude and occurrence correlate strongly with clinical ratings of tremor severity. Discussion: Transducers provide measurements of tremor amplitude that are objective, precise, and valid, but the precision and accuracy of transducers are mitigated by natural variability in tremor amplitude. This variability is so great that the minimum detectable change in amplitude, exceeding random variability, is comparable for scales and transducers. Research is needed to determine the feasibility of detecting smaller change using averaged data from continuous long-term recordings with wearable transducers.

  9. Sensitivity limits of capacitive transducer for gravitational wave resonant antennas

    Energy Technology Data Exchange (ETDEWEB)

    Bassan, M; Pizzella, G [Rome Tor Vergata Univ. (Italy). Dip. di Fisica

    1996-12-01

    It is analyzed the performance of a resonant gravitational wave antenna equipped with a resonant, d.c. biased capacitive transducer, an untuned superconducting matching circuit and a d.c. Squid. It is derived simple relations for the detector energy sensitivity that serve as guidelines for device development and it is shown that, with reasonable improvements in Squid technology, an effective temperature for burst detection of 2miK can be achieved.

  10. Damage detection with concentrated configurations of piezoelectric transducers

    International Nuclear Information System (INIS)

    Wandowski, T; Malinowski, P; Ostachowicz, W M

    2011-01-01

    In this paper results of investigation on concentrated piezoelectric networks with different configurations are presented. They were used for elastic wave generation and acquisition. The elastic wave propagation phenomenon was used for damage localization in thin aluminium panels. This approach utilized the fact that any discontinuities existing in structural elements cause local changes of physical material properties which affect elastic wave propagation. Elastic waves were excited and received using piezoelectric transducer networks with different element arrangements. The method of transducer placement and the number of piezoelectric elements used had an influence on the accuracy of the damage localization algorithm. Obviously, the more elements there were, the more data had to be processed. After the acquisition process signal processing was conducted in order to create damage influence maps. These maps presents elastic wave energy connected with reflection from discontinuities. In order to create such a map a computer program was developed that assigns a mesh of points to the panel surface. At each point the energy of elastic wave reflection was calculated. This energy was extracted from the acquired signals. This paper summarizes an extensive experimental investigation that included three damage scenarios and twelve transducer configurations

  11. Influence of a direct-fed microbial and xylanase enzyme on the dietary energy uptake efficiency and performance of broiler chickens.

    Science.gov (United States)

    Murugesan, Ganapathi Raj; Persia, Michael E

    2015-09-01

    Efficacy of a multi-strain direct-fed microbial product (PoultryStar(®) ME; PS) and a xylanase enzyme product on the dietary energy utilization efficiency and resulting performance in broiler chickens was evaluated. Apart from performance parameters, cecal and serum metabolites and activities of hepatic enzymes involved in energy metabolism were also determined. Ross 308 chicks were fed one of four experimental diets [control (CON), CON + PS, CON + xylanase and CON + PS + xylanase] using a 2 × 2 factorial arrangement from 1-21 days of age. Cecal proportions of propionate and butyrate, as well as total short-chain fatty acid concentration were increased (P energy uptake and hepatic energy retention. The combination additively increased the FCR, suggesting involvement of synergistic modes of actions. © 2014 Society of Chemical Industry.

  12. Pancreatic Enzymes

    Science.gov (United States)

    ... Contact Us DONATE NOW GENERAL DONATION PURPLESTRIDE Pancreatic enzymes Home Facing Pancreatic Cancer Living with Pancreatic Cancer ... and see a registered dietitian. What are pancreatic enzymes? Pancreatic enzymes help break down fats, proteins and ...

  13. Tunable-angle wedge transducer for improved acoustophoretic control in a microfluidic chip

    DEFF Research Database (Denmark)

    Iranmanesh, I.; Barnkob, Rune; Bruus, Henrik

    2012-01-01

    We present a tunable-angle wedge ultrasound transducer for improved control of microparticle acoustophoresis in a microfluidic chip. The transducer is investigated by analyzing the pattern of aligned particles and induced acoustic energy density while varying the system geometry, transducer...... in geometry and that the coupling angle may be used as an additional tuning parameter for improved acoustophoretic control with single-frequency actuation. Further, we find that frequency-modulation actuation is suitable for diminishing such tuning effects and that it is a robust method to produce uniform...... coupling angle, and transducer actuation method (single-frequency actuation or frequency-modulation actuation). The energy-density analysis is based on measuring the transmitted light intensity through a microfluidic channel filled with a suspension of 5-μm-diameter beads and the results with the tunable-angle...

  14. Capacitance high temperature strain transducer by Interatom

    International Nuclear Information System (INIS)

    Fortmann, M.

    1987-01-01

    Special strain transducers are necessary to perform structure mechanical experiments on real components under creep-fatigue load. The new development of the transducer was able to solve the problem. In the meantime, different characteristics of the transducer have been examined and many successful applications have been effected. Some important aspects are given in this report. Up to now the longest operation period has been 24000 h on a pipe at 630 0 C service temperature in a conventional power station. (orig./DG) [de

  15. Progress towards developing neutron tolerant magnetostrictive and piezoelectric transducers

    Energy Technology Data Exchange (ETDEWEB)

    Reinhardt, Brian; Tittmann, Bernhard [The Pennsylvania State University (United States); Rempe, Joy; Daw, Joshua [Idaho National Laboratory (United States); Kohse, Gordon; Carpenter, David; Ames, Michael; Ostrovsky, Yakov [Massachusetts Institute of Technology (United States); Ramuhalli, Pradeep; Montgomery, Robert [Pacific Northwest National Laboratory (United States); Chien, Hualte [Argonne National Laboratory (United States); Wernsman, Bernard [Bechtel Marine Propulsion Corp (United States)

    2015-03-31

    Current generation light water reactors (LWRs), sodium cooled fast reactors (SFRs), small modular reactors (SMRs), and next generation nuclear plants (NGNPs) produce harsh environments in and near the reactor core that can severely tax material performance and limit component operational life. To address this issue, several Department of Energy Office of Nuclear Energy (DOE-NE) research programs are evaluating the long duration irradiation performance of fuel and structural materials used in existing and new reactors. In order to maximize the amount of information obtained from Material Testing Reactor (MTR) irradiations, DOE is also funding development of enhanced instrumentation that will be able to obtain in-situ, real-time data on key material characteristics and properties, with unprecedented accuracy and resolution. Such data are required to validate new multi-scale, multi-physics modeling tools under development as part of a science-based, engineering driven approach to reactor development. It is not feasible to obtain high resolution/microscale data with the current state of instrumentation technology. However, ultrasound-based sensors offer the ability to obtain such data if it is demonstrated that these sensors and their associated transducers are resistant to high neutron flux, high gamma radiation, and high temperature. To address this need, the Advanced Test Reactor National Scientific User Facility (ATR-NSUF) is funding an irradiation, led by PSU, at the Massachusetts Institute of Technology Research Reactor to test the survivability of ultrasound transducers. As part of this effort, PSU and collaborators have designed, fabricated, and provided piezoelectric and magnetostrictive transducers that are optimized to perform in harsh, high flux, environments. Four piezoelectric transducers were fabricated with either aluminum nitride, zinc oxide, or bismuth titanate as the active element that were coupled to either Kovar or aluminum waveguides and two

  16. Progress towards developing neutron tolerant magnetostrictive and piezoelectric transducers

    Science.gov (United States)

    Reinhardt, Brian; Tittmann, Bernhard; Rempe, Joy; Daw, Joshua; Kohse, Gordon; Carpenter, David; Ames, Michael; Ostrovsky, Yakov; Ramuhalli, Pradeep; Montgomery, Robert; Chien, Hualte; Wernsman, Bernard

    2015-03-01

    Current generation light water reactors (LWRs), sodium cooled fast reactors (SFRs), small modular reactors (SMRs), and next generation nuclear plants (NGNPs) produce harsh environments in and near the reactor core that can severely tax material performance and limit component operational life. To address this issue, several Department of Energy Office of Nuclear Energy (DOE-NE) research programs are evaluating the long duration irradiation performance of fuel and structural materials used in existing and new reactors. In order to maximize the amount of information obtained from Material Testing Reactor (MTR) irradiations, DOE is also funding development of enhanced instrumentation that will be able to obtain in-situ, real-time data on key material characteristics and properties, with unprecedented accuracy and resolution. Such data are required to validate new multi-scale, multi-physics modeling tools under development as part of a science-based, engineering driven approach to reactor development. It is not feasible to obtain high resolution/microscale data with the current state of instrumentation technology. However, ultrasound-based sensors offer the ability to obtain such data if it is demonstrated that these sensors and their associated transducers are resistant to high neutron flux, high gamma radiation, and high temperature. To address this need, the Advanced Test Reactor National Scientific User Facility (ATR-NSUF) is funding an irradiation, led by PSU, at the Massachusetts Institute of Technology Research Reactor to test the survivability of ultrasound transducers. As part of this effort, PSU and collaborators have designed, fabricated, and provided piezoelectric and magnetostrictive transducers that are optimized to perform in harsh, high flux, environments. Four piezoelectric transducers were fabricated with either aluminum nitride, zinc oxide, or bismuth titanate as the active element that were coupled to either Kovar or aluminum waveguides and two

  17. Transducers and microprocessors in oceanographic applications

    Digital Repository Service at National Institute of Oceanography (India)

    Desai, R.G.P.; Desa, E.

    Transducers used for the sensing of the ten most measured marine parameters have been described in this paper. The ten parameters have been classed under 5 sensor types, namely temperature, pressure, salinity, currents and waves. For each sensor...

  18. A rectangle-type linear ultrasonic motor using longitudinal vibration transducers with four driving feet.

    Science.gov (United States)

    Liu, Yingxiang; Chen, Weishan; Liu, Junkao; Shi, Shengjun

    2013-04-01

    To make full use of the vibrational energy of a longitudinal transducer, a rectangle-type linear ultrasonic motor with four driving feet is proposed in this paper. This new motor consists of four longitudinal vibration transducers which are arranged in a rectangle and form an enclosed construction. Lead zirconate titanate ceramics are embedded into the middle of the transducer and fastened by a wedge-caulking mechanism. Each transducer includes an exponentially shaped horn located on each end. The horns of the vertical transducers intersect at the base of the horizontal transducers' horns; the tip ends of the horizontal transducers' horns are used as the driving feet. Longitudinal vibrations are superimposed in the motor and generate elliptical movements at the tip ends of the horns. The working principle of the proposed motor is analyzed. The resonance frequencies of two working modes are tuned to be close to each other by adjusting the structural parameters. Transient analysis is developed to gain the vibration characteristics of the motor. A prototype motor is fabricated and measured. The vibration test results verify the feasibility of the proposed design. Typical output of the prototype is a no-load speed of 928 mm/s and maximum thrust force of 60 N at a voltage of 200 Vrms.

  19. Thermal effects on transducer material for heat assisted magnetic recording application

    Energy Technology Data Exchange (ETDEWEB)

    Ji, Rong, E-mail: Ji-Rong@dsi.a-star.edu.sg; Xu, Baoxi; Cen, Zhanhong; Ying, Ji Feng; Toh, Yeow Teck [Data Storage Institute, Agency for Science, Technology and Research (A-STAR), 5 Engineering Drive 1, Singapore 117608 (Singapore)

    2015-05-07

    Heat Assisted Magnetic Recording (HAMR) is a promising technology for next generation hard disk drives with significantly increased data recording capacities. In HAMR, an optical near-field transducer (NFT) is used to concentrate laser energy on a magnetic recording medium to fulfill the heat assist function. The key components of a NFT are transducer material, cladding material, and adhesion material between the cladding and the transducer materials. Since transducer materials and cladding materials have been widely reported, this paper focuses on the adhesion materials between the Au transducer and the Al{sub 2}O{sub 3} cladding material. A comparative study for two kinds of adhesion material, Ta and Cr, has been conducted. We found that Ta provides better thermal stability to the whole transducer than Cr. This is because after thermal annealing, chromium forms oxide material at interfaces and chromium atoms diffuse remarkably into the Au layer and react with Au to form Au alloy. This study also provides insights on the selection of adhesion material for HAMR transducer.

  20. Effect of the Matching Circuit on the Electromechanical Characteristics of Sandwiched Piezoelectric Transducers

    Directory of Open Access Journals (Sweden)

    Shuyu Lin

    2017-02-01

    Full Text Available The input electrical impedance behaves as a capacitive when a piezoelectric transducer is excited near its resonance frequency. In order to increase the energy transmission efficiency, a series or parallel inductor should be used to compensate the capacitive impedance of the piezoelectric transducer. In this paper, the effect of the series matching inductor on the electromechanical characteristics of the piezoelectric transducer is analyzed. The dependency of the resonance/anti-resonance frequency, the effective electromechanical coupling coefficient, the electrical quality factor and the electro-acoustical efficiency on the matching inductor is obtained. It is shown that apart from compensating the capacitive impedance of the piezoelectric transducer, the series matching inductor can also change the electromechanical characteristics of the piezoelectric transducer. When series matching inductor is increased, the resonance frequency is decreased and the anti-resonance unchanged; the effective electromechanical coupling coefficient is increased. For the electrical quality factor and the electroacoustic efficiency, the dependency on the matching inductor is different when the transducer is operated at the resonance and the anti-resonance frequency. The electromechanical characteristics of the piezoelectric transducer with series matching inductor are measured. It is shown that the theoretically predicted relationship between the electromechanical characteristics and the series matching inductor is in good agreement with the experimental results.

  1. Effect of the Matching Circuit on the Electromechanical Characteristics of Sandwiched Piezoelectric Transducers.

    Science.gov (United States)

    Lin, Shuyu; Xu, Jie

    2017-02-10

    The input electrical impedance behaves as a capacitive when a piezoelectric transducer is excited near its resonance frequency. In order to increase the energy transmission efficiency, a series or parallel inductor should be used to compensate the capacitive impedance of the piezoelectric transducer. In this paper, the effect of the series matching inductor on the electromechanical characteristics of the piezoelectric transducer is analyzed. The dependency of the resonance/anti-resonance frequency, the effective electromechanical coupling coefficient, the electrical quality factor and the electro-acoustical efficiency on the matching inductor is obtained. It is shown that apart from compensating the capacitive impedance of the piezoelectric transducer, the series matching inductor can also change the electromechanical characteristics of the piezoelectric transducer. When series matching inductor is increased, the resonance frequency is decreased and the anti-resonance unchanged; the effective electromechanical coupling coefficient is increased. For the electrical quality factor and the electroacoustic efficiency, the dependency on the matching inductor is different when the transducer is operated at the resonance and the anti-resonance frequency. The electromechanical characteristics of the piezoelectric transducer with series matching inductor are measured. It is shown that the theoretically predicted relationship between the electromechanical characteristics and the series matching inductor is in good agreement with the experimental results.

  2. Performance of Honeywell silicon pressure transducers

    Digital Repository Service at National Institute of Oceanography (India)

    VijayKumar, K.; Joseph, A.; Desai, R.G.P.; Nagvekar, S.; Prabhudesai, S.; Damodaran, V.

    pressure. The precision pressure transducer – ruggedized (PPTR) manufactured by Honeywell is provided with a special “Hastelloy” material isolation-diaphragm to protect the transducer port against corrosive effects during its prolonged exposure...-scale output (an intelligent technique anufacturers to hide the non-linearity of the product at all data points below ore realistic estimate of linearity is obtained by ean of a few samples) based on the corresponding true ethod employed by performance...

  3. In vivo continuous and simultaneous monitoring of brain energy substrates with a multiplex amperometric enzyme-based biosensor device.

    Science.gov (United States)

    Cordeiro, C A; de Vries, M G; Ngabi, W; Oomen, P E; Cremers, T I F H; Westerink, B H C

    2015-05-15

    Enzyme-based amperometric biosensors are widely used for monitoring key biomarkers. In experimental neuroscience there is a growing interest in in vivo continuous and simultaneous monitoring of metabolism-related biomarkers, like glucose, lactate and pyruvate. The use of multiplex biosensors will provide better understanding of brain energy metabolism and its role in neuropathologies such as diabetes, ischemia, and epilepsy. We have developed and characterized an implantable multiplex microbiosensor device (MBD) for simultaneous and continuous in vivo monitoring of glucose, lactate, and pyruvate. First, we developed and characterized amperometric microbiosensors for monitoring lactate and pyruvate. In vitro evaluation allowed us to choose the most suitable biosensors for incorporation into the MBD, along with glucose and background biosensors. Fully assembled MBDs were characterized in vitro. The calculated performance parameters (LOD, LR, LRS, IMAX and appKM) showed that the multiplex MBD was highly selective and sensitive (LRS≥100 nA/mM) for each analyte and within an adequate range for in vivo application. Finally, MBDs were implanted in the mPFC of anesthetized adult male Wistar rats for in vivo evaluation. Following an equilibration period, baseline brain levels of glucose (1.3±0.2 mM), lactate (1.5±0.4 mM) and pyruvate (0.3±0.1 mM) were established. Subsequently, the MBDs recorded the responses of the animals when submitted to hyperglycemic (40% glucose i.v.) and hypoglycemic (5 U/kg insulin i.v.) challenges. Afterwards, MBDs were recalibrated to convert electrochemical readings into accurate substrate concentrations and to assess biofouling. The presented MBD can monitor simultaneously multiple biomarkers in vivo. Copyright © 2014 Elsevier B.V. All rights reserved.

  4. Proof-of-concept experimental study of damage detection of concrete piles using embedded piezoceramic transducers

    International Nuclear Information System (INIS)

    Wang, R L; Gu, H; Song, G; Mo, Y L

    2013-01-01

    This paper presents a proof-of-concept experimental study of an innovative active-sensing approach for damage detection of concrete piles by using embedded piezoceramic transducers. In the proposed active-sensing approach, one piezoceramic transducer is used as an actuator to generate a stress wave to propagate through the concrete pile and the other distributed piezoceramic transducers are used as sensors to detect the wave response. Cracks or damage inside the concrete structure act as stress relief in the wave propagation path. The amplitude of the wave and the transmission energy will decrease due to the existence of cracks or damage. Experiments were performed on two bored piles instrumented with embedded piezoceramic transducers. The experimental results demonstrate the effectiveness of the proposed approach for pile damage detection. (fast track communication)

  5. Active acoustical impedance using distributed electrodynamical transducers.

    Science.gov (United States)

    Collet, M; David, P; Berthillier, M

    2009-02-01

    New miniaturization and integration capabilities available from emerging microelectromechanical system (MEMS) technology will allow silicon-based artificial skins involving thousands of elementary actuators to be developed in the near future. SMART structures combining large arrays of elementary motion pixels coated with macroscopic components are thus being studied so that fundamental properties such as shape, stiffness, and even reflectivity of light and sound could be dynamically adjusted. This paper investigates the acoustic impedance capabilities of a set of distributed transducers connected with a suitable controlling strategy. Research in this domain aims at designing integrated active interfaces with a desired acoustical impedance for reaching an appropriate global acoustical behavior. This generic problem is intrinsically connected with the control of multiphysical systems based on partial differential equations (PDEs) and with the notion of multiscaled physics when a dense array of electromechanical systems (or MEMS) is considered. By using specific techniques based on PDE control theory, a simple boundary control equation capable of annihilating the wave reflections has been built. The obtained strategy is also discretized as a low order time-space operator for experimental implementation by using a dense network of interlaced microphones and loudspeakers. The resulting quasicollocated architecture guarantees robustness and stability margins. This paper aims at showing how a well controlled semidistributed active skin can substantially modify the sound transmissibility or reflectivity of the corresponding homogeneous passive interface. In Sec. IV, numerical and experimental results demonstrate the capabilities of such a method for controlling sound propagation in ducts. Finally, in Sec. V, an energy-based comparison with a classical open-loop strategy underlines the system's efficiency.

  6. Mechano-electric optoisolator transducer with hysteresis

    International Nuclear Information System (INIS)

    Ciurus, I M; Dimian, M; Graur, A

    2011-01-01

    This article presents a theoretical and experimental study of designing a mechano-electric optoisolator transducer with hysteresis. Our research is centred upon designing transducers on the basis of optical sensors, as photoelectric conversions eliminate the influence of electromagnetic disturbances. Conversion of the rotation/translation motions into electric signals is performed with the help of a LED-photoresistor Polaroid optocoupler. The driver of the optocoupler's transmitter module is an independent current source. The signal conditioning circuit is a Schmitt trigger circuit. The device is designed to be applied in the field of automation and mechatronics.

  7. Immune Algorithm Complex Method for Transducer Calibration

    Directory of Open Access Journals (Sweden)

    YU Jiangming

    2014-08-01

    Full Text Available As a key link in engineering test tasks, the transducer calibration has significant influence on accuracy and reliability of test results. Because of unknown and complex nonlinear characteristics, conventional method can’t achieve satisfactory accuracy. An Immune algorithm complex modeling approach is proposed, and the simulated studies on the calibration of third multiple output transducers is made respectively by use of the developed complex modeling. The simulated and experimental results show that the Immune algorithm complex modeling approach can improve significantly calibration precision comparison with traditional calibration methods.

  8. The Current State of Silicone-Based Dielectric Elastomer Transducers

    DEFF Research Database (Denmark)

    Madsen, Frederikke Bahrt; Daugaard, Anders Egede; Hvilsted, Søren

    2016-01-01

    class of transducer due to their inherent lightweight and potentially large strains. For the field to progress towards industrial implementation, a leap in material devel- opment is required, specifically targeting longer lifetime and higher energy densities to provide more efficient transduction at lower...... driving voltages. In this review, the current state of sili- cone elastomers for DETs is summarised and critically discussed, including commercial elastomers, composites, polymer blends, grafted elastomers and complex network structures. For future developments in the field it is essential that all aspects...

  9. Ultrasonic non-destructive testing of pieces of complex geometry with a flexible phased array transducer

    Science.gov (United States)

    Chatillon; Cattiaux; Serre; Roy

    2000-03-01

    Ultrasonic non-destructive testing of components of complex geometry in the nuclear industry faces several difficulties: sensitivity variations due to unmatched contact, inaccurate localization of defects due to variations of transducer orientation, and uncovered area of the component. To improve the performances of such testing and defect characterization, we propose a new concept of ultrasonic contact phased array transducer. The phased array transducer has a flexible radiating surface able to fit the actual surface of the piece to optimize the contact and thus the sensitivity of the test. To control the transmitted field, and therefore to improve the defect characterization, a delay law optimizing algorithm is developed. To assess the capability of such a transducer, the Champ-Sons model, developed at the French Atomic Energy Commission for predicting field radiated by arbitrary transducers into pieces, has to be extended to sources directly in contact with pieces of complex geometry. The good behavior of this new type of probe predicted by computations is experimentally validated with a jointed transducer positioned on pieces of various profiles.

  10. Effect of wheat cultivar and enzyme addition to broiler chicken diets on nutrient digestibility, performance, and apparent metabolizable energy content.

    NARCIS (Netherlands)

    Gutierrez del Alamo Oms, A.; Verstegen, M.W.A.; Hartog, den L.A.; Villamide, M.J.

    2008-01-01

    A total of 5,000 one-day-old male broiler chickens were assigned to 8 different treatments in a 4 x 2 factorial design. Four wheat cultivars (Amiro, Guadalupe, Isengrain, and Horzal) and 2 levels (0 or 1 kg/t of feed) of an enzyme cocktail (Avizyme 1300, xylanase, 2,500 U/kg and protease, 800 U/kg)

  11. In vivo continuous and simultaneous monitoring of brain energy substrates with a multiplex amperometric enzyme-based biosensor device

    NARCIS (Netherlands)

    De Lima Braga Lopes Cordeiro, Carlos; de Vries, M.G.; Ngabi, W; Oomen, P.E.; Cremers, T.I.F.H.; Westerink, B.H.C.

    2015-01-01

    Enzyme-based amperometric biosensors are widely used for monitoring key biomarkers. In experimental neuroscience there is a growing interest in in vivo continuous and simultaneous monitoring of metabolism-related biomarkers, like glucose, lactate and pyruvate. The use of multiplex biosensors will

  12. Electromechanically active polymer transducers: research in Europe

    Science.gov (United States)

    Carpi, Federico; Graz, Ingrid; Jager, Edwin; Ladegaard Skov, Anne; Vidal, Frédéric

    2013-10-01

    Smart materials and structures based on electromechanically active polymers (EAPs) represent a fast growing and stimulating field of research and development. EAPs are materials capable of changing dimensions and/or shape in response to suitable electrical stimuli. They are commonly classified in two major families: ionic EAPs (activated by an electrically induced transport of ions and/or solvent) and electronic EAPs (activated by electrostatic forces). These polymers show interesting properties, such as sizable active strains and/or stresses in response to electrical driving, high mechanical flexibility, low density, structural simplicity, ease of processing and scalability, no acoustic noise and, in most cases, low costs. Since many of these characteristics can also describe natural muscle tissues from an engineering standpoint, it is not surprising that EAP transducers are sometimes also referred to as 'muscle-like smart materials' or 'artificial muscles'. They are used not only to generate motion, but also to sense or harvest energy from it. In particular, EAP electromechanical transducers are studied for applications that can benefit from their 'biomimetic' characteristics, with possible usages from the micro- to the macro-scale, spanning several disciplines, such as mechatronics, robotics, automation, biotechnology and biomedical engineering, haptics, fluidics, optics and acoustics. Currently, the EAP field is just undergoing its initial transition from academic research into commercialization, with companies starting to invest in this technology and the first products appearing on the market. This focus issue is intentionally aimed at gathering contributions from the most influential European groups working in the EAP field. In fact, today Europe hosts the broadest EAP community worldwide. The rapid expansion of the EAP field in Europe, where it historically has strong roots, has stimulated the creation of the 'European Scientific Network for Artificial

  13. Low-Energy Solvents For Carbon Dioxide Capture Enabled By A Combination Of Enzymes And Vacuum Regeneration

    Energy Technology Data Exchange (ETDEWEB)

    Salmon, Sonja [Novozymes North America, Inc., Franklinton, NC (United States); House, Alan [Novozymes North America, Inc., Franklinton, NC (United States); Liu, Kun [Univ. of Kentucky, Lexington, KY (United States); Frimpong, Reynolds [Univ. of Kentucky, Lexington, KY (United States); Liu, Kunlei [Univ. of Kentucky, Lexington, KY (United States); Freeman, Charles [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Whyatt, Greg [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Slater, Jonathan [Doosan Babcock, Renfew (United Kingdom); Fitzgerald, David [Doosan Babcock, Renfew (United Kingdom)

    2015-08-31

    An integrated bench-scale system combining the attributes of the bio-renewable enzyme carbonic anhydrase (CA) with low-enthalpy CO2 absorption solvents and vacuum regeneration was designed, built and operated for 500 hours using simulated flue gas. The objective was to develop a CO2 capture process with improved efficiency and sustainability when compared to NETL Case 10 monoethanolamine (MEA) scrubbing technology. The use of CA accelerates inter-conversion between dissolved CO2 and bicarbonate ion to enhance CO2 absorption, and the use of low enthalpy CO2 absorption solvents makes it possible to regenerate the solvent at lower temperatures relative to the reference MEA-based solvent. The vacuum regeneration-based integrated bench-scale system operated successfully for an accumulated 500 hours using aqueous 23.5 wt% K2CO3-based solvent containing 2.5 g/L enzyme to deliver an average 84% CO2 capture when operated with a 20% enzyme replenishment rate per ~7 hour steady-state run period. The total inlet gas flow was 30 standard liters per minute with 15% CO2 and 85% N2. The absorber temperature was 40°C and the stripper operated under 35 kPa pressure with an approximate 77°C stripper bottom temperature. Tests with a 30°C absorber temperature delivered >90% capture. On- and off-line operational measurements provided a full process data set, with recirculating enzyme, that allowed for enzyme replenishment and absorption/desorption kinetic parameter calculations. Dissolved enzyme replenishment and conventional process controls were demonstrated as straightforward approaches to maintain system performance. Preliminary evaluation of a novel flow-through ultrasonically enhanced regeneration system was also conducted, yet resulted in CO2 release within the range of temperature-dependent release, and further work would be needed to validate the benefits of ultrasonic enhanced stripping. A full technology assessment was completed in which four techno-economic cases for

  14. A method for predicting individual residue contributions to enzyme specificity and binding-site energies, and its application to MTH1.

    Science.gov (United States)

    Stewart, James J P

    2016-11-01

    A new method for predicting the energy contributions to substrate binding and to specificity has been developed. Conventional global optimization methods do not permit the subtle effects responsible for these properties to be modeled with sufficient precision to allow confidence to be placed in the results, but by making simple alterations to the model, the precisions of the various energies involved can be improved from about ±2 kcal mol -1 to ±0.1 kcal mol -1 . This technique was applied to the oxidized nucleotide pyrophosphohydrolase enzyme MTH1. MTH1 is unusual in that the binding and reaction sites are well separated-an advantage from a computational chemistry perspective, as it allows the energetics involved in docking to be modeled without the need to consider any issues relating to reaction mechanisms. In this study, two types of energy terms were investigated: the noncovalent interactions between the binding site and the substrate, and those responsible for discriminating between the oxidized nucleotide 8-oxo-dGTP and the normal dGTP. Both of these were investigated using the semiempirical method PM7 in the program MOPAC. The contributions of the individual residues to both the binding energy and the specificity of MTH1 were calculated by simulating the effect of mutations. Where comparisons were possible, all calculated results were in agreement with experimental observations. This technique provides fresh insight into the binding mechanism that enzymes use for discriminating between possible substrates.

  15. Fiber-optic coupled pressure transducer

    International Nuclear Information System (INIS)

    Tallman, C.R.; Wingate, F.P.; Ballard, E.O.

    1979-01-01

    A fiber-optic coupled pressure transducer was developed for measurement of pressure transients produced by fast electrical discharges in laser cavities. A detailed description of the design and performance will be given. Shock tube performance and measurements in direct electrical discharge regions will be presented

  16. Eliminating transducer distortion in acoustic measurements

    DEFF Research Database (Denmark)

    Agerkvist, Finn T.; Torras Rosell, Antoni; McWalter, Richard Ian

    2014-01-01

    This paper investigates the in uence of nonlinear components that contaminate the linear response of acoustic transducer, and presents a method for eliminating the in uence of nonlinearities in acoustic measurements. The method is evaluated on simulated as well as experimental data, and is shown...

  17. Ferroelectret non-contact ultrasonic transducers

    Czech Academy of Sciences Publication Activity Database

    Bovtun, Viktor; Döring, J.; Bartusch, J.; Beck, U.; Erhard, A.; Yakymenko, Y.

    2007-01-01

    Roč. 88, č. 4 (2007), s. 737-743 ISSN 0947-8396 R&D Projects: GA ČR(CZ) GA202/06/0403 Institutional research plan: CEZ:AV0Z10100520 Keywords : ferroelectrets * polymers * ultrasonic transducers Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.857, year: 2007

  18. Linearization of resistance thermometers and other transducers

    DEFF Research Database (Denmark)

    Diamond, Joseph M.

    1970-01-01

    deflection output or to null balance output. The application to the common temperature transducers is considered. It is shown that thermistors, linear metals (e.g., copper), and nickel can be linearized in terms of temperature, but platinum cannot be. If linearization is desired in terms of the reciprocal...

  19. Characterisation and Modelling of MEMS Ultrasonic Transducers

    International Nuclear Information System (INIS)

    Teng, M F; Hariz, A J

    2006-01-01

    Silicon ultrasonic transducer micro arrays based on micro-electro-mechanicalsystem (MEMS) technologies are gaining popularity for applications in sonar sensing and excitation. A current challenge for many researchers is modelling the dynamic performance of these and other micro-mechanical devices to ascertain their performance and explain experimental observations reported. In this work, the performance simulation of a MEMS ultrasonic transducer array made from silicon nitride has been successfully carried out using CoventorWare package. The dynamic response of the entire transducer array was characterised, and the results were compared with theoretical predictions. Individual elements were found to vibrate with Bessel-like displacement patterns, and they were resonant at approximately 3 MHz, depending on thickness and lateral dimensions. The frequency shows a linear dependence around the common thickness of 2 μm. Peak displacement levels were examined as a function of frequency, DC bias voltage, and AC drive voltage. Accounting for fabrication variations, and uniformity variations across the wafer, the full array showed minimal variations in peak out-of-plane displacement levels across the device, and isolated elements that were over-responsive and under-responsive. Presently, the effect of observed variations across the array on the performance of the transducers and their radiated fields are being examined

  20. Features calibration of the dynamic force transducers

    Science.gov (United States)

    Sc., M. Yu Prilepko D.; Lysenko, V. G.

    2018-04-01

    The article discusses calibration methods of dynamic forces measuring instruments. The relevance of work is dictated by need to valid definition of the dynamic forces transducers metrological characteristics taking into account their intended application. The aim of this work is choice justification of calibration method, which provides the definition dynamic forces transducers metrological characteristics under simulation operating conditions for determining suitability for using in accordance with its purpose. The following tasks are solved: the mathematical model and the main measurements equation of calibration dynamic forces transducers by load weight, the main budget uncertainty components of calibration are defined. The new method of dynamic forces transducers calibration with use the reference converter “force-deformation” based on the calibrated elastic element and measurement of his deformation by a laser interferometer is offered. The mathematical model and the main measurements equation of the offered method is constructed. It is shown that use of calibration method based on measurements by the laser interferometer of calibrated elastic element deformations allows to exclude or to considerably reduce the uncertainty budget components inherent to method of load weight.

  1. Enzyme Informatics

    Science.gov (United States)

    Alderson, Rosanna G.; Ferrari, Luna De; Mavridis, Lazaros; McDonagh, James L.; Mitchell, John B. O.; Nath, Neetika

    2012-01-01

    Over the last 50 years, sequencing, structural biology and bioinformatics have completely revolutionised biomolecular science, with millions of sequences and tens of thousands of three dimensional structures becoming available. The bioinformatics of enzymes is well served by, mostly free, online databases. BRENDA describes the chemistry, substrate specificity, kinetics, preparation and biological sources of enzymes, while KEGG is valuable for understanding enzymes and metabolic pathways. EzCatDB, SFLD and MACiE are key repositories for data on the chemical mechanisms by which enzymes operate. At the current rate of genome sequencing and manual annotation, human curation will never finish the functional annotation of the ever-expanding list of known enzymes. Hence there is an increasing need for automated annotation, though it is not yet widespread for enzyme data. In contrast, functional ontologies such as the Gene Ontology already profit from automation. Despite our growing understanding of enzyme structure and dynamics, we are only beginning to be able to design novel enzymes. One can now begin to trace the functional evolution of enzymes using phylogenetics. The ability of enzymes to perform secondary functions, albeit relatively inefficiently, gives clues as to how enzyme function evolves. Substrate promiscuity in enzymes is one example of imperfect specificity in protein-ligand interactions. Similarly, most drugs bind to more than one protein target. This may sometimes result in helpful polypharmacology as a drug modulates plural targets, but also often leads to adverse side-effects. Many cheminformatics approaches can be used to model the interactions between druglike molecules and proteins in silico. We can even use quantum chemical techniques like DFT and QM/MM to compute the structural and energetic course of enzyme catalysed chemical reaction mechanisms, including a full description of bond making and breaking. PMID:23116471

  2. Biasing of Capacitive Micromachined Ultrasonic Transducers.

    Science.gov (United States)

    Caliano, Giosue; Matrone, Giulia; Savoia, Alessandro Stuart

    2017-02-01

    Capacitive micromachined ultrasonic transducers (CMUTs) represent an effective alternative to piezoelectric transducers for medical ultrasound imaging applications. They are microelectromechanical devices fabricated using silicon micromachining techniques, developed in the last two decades in many laboratories. The interest for this novel transducer technology relies on its full compatibility with standard integrated circuit technology that makes it possible to integrate on the same chip the transducers and the electronics, thus enabling the realization of extremely low-cost and high-performance devices, including both 1-D or 2-D arrays. Being capacitive transducers, CMUTs require a high bias voltage to be properly operated in pulse-echo imaging applications. The typical bias supply residual ripple of high-quality high-voltage (HV) generators is in the millivolt range, which is comparable with the amplitude of the received echo signals, and it is particularly difficult to minimize. The aim of this paper is to analyze the classical CMUT biasing circuits, highlighting the features of each one, and to propose two novel HV generator architectures optimized for CMUT biasing applications. The first circuit proposed is an ultralow-residual ripple (generator that uses an extremely stable sinusoidal power oscillator topology. The second circuit employs a commercially available integrated step-up converter characterized by a particularly efficient switching topology. The circuit is used to bias the CMUT by charging a buffer capacitor synchronously with the pulsing sequence, thus reducing the impact of the switching noise on the received echo signals. The small area of the circuit (about 1.5 cm 2 ) makes it possible to generate the bias voltage inside the probe, very close to the CMUT, making the proposed solution attractive for portable applications. Measurements and experiments are shown to demonstrate the effectiveness of the new approaches presented.

  3. Parameter sensitivity study of a Field II multilayer transducer model on a convex transducer

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2009-01-01

    A multilayer transducer model for predicting a transducer impulse response has in earlier works been developed and combined with the Field II software. This development was tested on current, voltage, and intensity measurements on piezoceramics discs (Bæk et al. IUS 2008) and a convex 128 element...... ultrasound imaging transducer (Bæk et al. ICU 2009). The model benefits from its 1D simplicity and hasshown to give an amplitude error around 1.7‐2 dB. However, any prediction of amplitude, phase, and attenuation of pulses relies on the accuracy of manufacturer supplied material characteristics, which may...... is a quantitative calibrated model for a complete ultrasound system. This includes a sensitivity study aspresented here.Statement of Contribution/MethodsThe study alters 35 different model parameters which describe a 128 element convex transducer from BK Medical Aps. The changes are within ±20 % of the values...

  4. Capacitive pressure transducer using flexible films. Junan film wo mochiita seiden yoryoshiki atsukaku transducer

    Energy Technology Data Exchange (ETDEWEB)

    Yamada, Y.; Tsuchida, N.; Imai, K. (Toyota Technological Institute, Aichi (Japan)); Fujita, K. (Nitto Denko Corp., Osaka (Japan)): Tsuboi, O. (Fujitsu Corp., Tokyo (Japan))

    1992-12-20

    This paper describes the design, manufacture, and evaluation of a capacitive pressure transducer made of polyimide films. The structure of a pressure transducer cell was first determined, and then, the deflection-stress and capacitance-load characteristics of the surface film were analyzed using finite element methods. For the practical stage of manufacture, a polyimide film was emboss processed and electrodes were deposited on the film to construct a pressure transducer cell to which a Schmidt-trigger detecting circuit was connected. As a consequence of the examination of operational characteristics of the cell, it was found that the actual relation between the deflection and load approximately agreed with the linear analyses, and that the capacitance depended with little hysteresis on the gap regardless of the native visco-elasticity of the film. Furthermore, small stick-slip vibration of a contact rubber surface was detected by the transducer to verify its high sensitivity. 17 refs., 18 figs.

  5. Folding and Function of Proteorhodopsins in Photoenergy Transducing Membranes

    Energy Technology Data Exchange (ETDEWEB)

    Spudich, John L. [University of Texas Medical School, Houston, TX (United States). Health Science Center, Dept. of Biochemistry and Molecular Biology

    2012-08-10

    The overall research objectives are to develop proteorhodopsin (PR) proteins as a model system for α-helical membrane protein insertion and folding, and to advance understanding of the diversity and mechanisms of PRs, a large family of photoenergy transducers (~4000 identified) abundant in the world’s oceans. Specific aims are: (1) To develop a high-efficiency genetic selection procedure for light-driven proton-pumping in E. coli cells. Such a procedure would provide a positive selection method for proper folding and function of PRs in the E. coli membrane. (2) Characterize flash-induced absorption changes and photocurrents in PR variants in organisms from various environments, and their expression level and function when expressed in E. coli. Subaims are to: (a) elucidate the relationship of the transport mechanism to mechanisms of other microbial rhodopsins, some of which like PRs function as ion transporters and some of which use light energy to activate signaling pathways (sensory rhodopsins); and (b) identify important residues and chemical events in light-driven proton transport by PRs. In addition to their importance to the energy of the biosphere PRs have attracted interest for their potential for use in making photoenergy-transducing membranes for bioengineering applications.

  6. An overheight vehicle bridge collision monitoring system using piezoelectric transducers

    Science.gov (United States)

    Song, G.; Olmi, C.; Gu, H.

    2007-04-01

    With increasing traffic volume follows an increase in the number of overheight truck collisions with highway bridges. The detection of collision impact and evaluation of the impact level is a critical issue in the maintenance of a concrete bridge. In this paper, an overheight collision detection and evaluation system is developed for concrete bridge girders using piezoelectric transducers. An electric circuit is designed to detect the impact and to activate a digital camera to take photos of the offending truck. Impact tests and a health monitoring test were conducted on a model concrete bridge girder by using three piezoelectric transducers embedded before casting. From the experimental data of the impact test, it can be seen that there is a linear relation between the output of sensor energy and the impact energy. The health monitoring results show that the proposed damage index indicates the level of damage inside the model concrete bridge girder. The proposed overheight truck-bridge collision detection and evaluation system has the potential to be applied to the safety monitoring of highway bridges.

  7. Lamb wave tuning curve calibration for surface-bonded piezoelectric transducers

    International Nuclear Information System (INIS)

    Sohn, Hoon; Lee, Sang Jun

    2010-01-01

    Surface-bonded lead zirconate titanate (PZT) transducers have been widely used for guided wave generation and measurement. For selective actuation and sensing of Lamb wave modes, the sizes of the transducers and the driving frequency of the input waveform should be tuned. For this purpose, a theoretical Lamb wave tuning curve (LWTC) of a specific transducer size is generally obtained. Here, the LWTC plots each Lamb wave mode' amplitude as a function of the driving frequency. However, a discrepancy between experimental and existing theoretical LWTCs has been observed due to little consideration of the bonding layer and the energy distribution between Lamb wave modes. In this study, calibration techniques for theoretical LWTCs are proposed. First, a theoretical LWTC is developed when circular PZT transducers are used for both Lamb wave excitation and sensing. Then, the LWTC is calibrated by estimating the effective PZT size with PZT admittance measurement. Finally, the energy distributions among symmetric and antisymmetric modes are taken into account for better prediction of the relative amplitudes between Lamb wave modes. The effectiveness of the proposed calibration techniques is examined through numerical simulations and experimental estimation of the LWTC using the circular PZT transducers instrumented on an aluminum plate

  8. Dissipation in vibrating superleak second sound transducers

    International Nuclear Information System (INIS)

    Giordano, N.

    1985-01-01

    We have performed an experimental study of the generation and detection of second sound in 4 He using vibrating superleak second sound transducers. At temperatures well below T/sub lambda/ and for low driving amplitudes, the magnitude of the generated second sound wave is proportional to the drive amplitude. However, near T/sub lambda/ and for high drive amplitudes this is no longer the case--instead, the second sound amplitude saturates. In this regime we also find that overtones of the drive frequency are generated. Our results suggest that this behavior is due to critical velocity effects in the pores of the superleak in the generator transducer. This type of measurement may prove to be a useful way in which to study critical velocity effects in confined geometries

  9. Ultrasonic transducer design for uniform insonation

    International Nuclear Information System (INIS)

    Harrison, G.H.; Balcer-Kubiczek, E.K.; McCulloch, D.

    1984-01-01

    Techniques used in transducer development for acoustical imaging have been evaluated for the purpose of producing broad, uniform ultrasonic fields from planar radiators. Such fields should be useful in hyperthermia, physical therapy, and ultrasonic bioeffects studies. Fourier inversion of the circ function yielded a source velocity distribution proportional to (P/r) exp ((-ik/2Z) (2Z/sup 2/+r/sup 2/)) J/sub 1/(krP/Z), where r is the radial source coordinate, k is the wave number, and P is the desired radius of uniform insonation at a depth Z in water. This source distribution can be truncated without significantly degrading the solution. A simpler solution consists of exponentially shading the edge of an otherwise uniformly excited disk transducer. This approach was successfully approximated experimentally

  10. Cymbal and BB underwater transducers and arrays

    Energy Technology Data Exchange (ETDEWEB)

    Newnham, R.E.; Zhang, J.; Alkoy, S.; Meyer, R.; Hughes, W.J.; Hladky-Hennion, A.C.; Cochran, J.; Markley, D. [Materials Research Laboratory, Penn State University, University Park, PA 16802 (United States)

    2002-09-01

    The cymbal is a miniaturized class V flextensional transducer that was developed for use as a shallow water sound projector and receiver. Single elements are characterized by high Q, low efficiency, and medium power output capability. Its low cost and thin profile allow the transducer to be assembled into large flexible arrays. Efforts were made to model both single elements and arrays using the ATILA code and the integral equation formulation (EQI).Millimeter size microprobe hydrophones (BBs) have been designed and fabricated from miniature piezoelectric hollow ceramic spheres for underwater applications such as mapping acoustic fields of projectors, and flow noise sensors for complex underwater structures. Green spheres are prepared from soft lead zirconate titanate powders using a coaxial nozzle slurry process. A compact hydrophone with a radially-poled sphere is investigated using inside and outside electrodes. Characterization of these hydrophones is done through measurement of hydrostatic piezoelectric charge coefficients, free field voltage sensitivities and directivity beam patterns. (orig.)

  11. Creaming enhancement in a liter scale ultrasonic reactor at selected transducer configurations and frequencies.

    Science.gov (United States)

    Juliano, Pablo; Temmel, Sandra; Rout, Manoj; Swiergon, Piotr; Mawson, Raymond; Knoerzer, Kai

    2013-01-01

    Recent research has shown that high frequency ultrasound (0.4-3 MHz), can enhance milkfat separation in small scale systems able to treat only a few milliliters of sample. In this work, the effect of ultrasonic standing waves on milkfat creaming was studied in a 6L reactor and the influence of different frequencies and transducer configurations in direct contact with the fluid was investigated. A recombined coarse milk emulsion with fat globules stained with oil-red-O dye was selected for the separation trials. Runs were performed with one or two transducers placed in vertical (parallel or perpendicular) and horizontal positions (at the reactor base) at 0.4, 1 and/or 2 MHz (specific energy 8.5 ± 0.6 kJ/kg per transducer). Creaming behavior was assessed by measuring the thickness of the separated cream layer. Other methods supporting this assessment included the measurement of fat content, backscattering, particle size distribution, and microscopy of samples taken at the bottom and top of the reactor. Most efficient creaming was found after treatment at 0.4 MHz in single and double vertical transducer configurations. Among these configurations, a higher separation rate was obtained when sonicating at 0.4 MHz in a vertical perpendicular double transducer setup. The horizontal transducer configuration promoted creaming at 2 MHz only. Fat globule size increase was observed when creaming occurred. This research highlights the potential for enhanced separation of milkfat in larger scale systems from selected transducer configurations in contact with a dairy emulsion, or emulsion splitting in general. Copyright © 2012 Elsevier B.V. All rights reserved.

  12. Design and fabrication of a double-sided piezoelectric transducer for harvesting vibration power

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Wei-Tsai; Chen, Ying-Chung [Department of Electrical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC (China); Kao, Kuo-Sheng [Department of Computer and Communication, Shu-Te University, Kaohsiung, Taiwan, ROC (China); Chu, Yu-Hsien [Department of Electrical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan, ROC (China); Cheng, Chien-Chuan, E-mail: chengccc@dlit.edu.tw [Department of Electronic Engineering, De Lin Institute of Technology, Taipei, Taiwan, ROC (China)

    2013-02-01

    This investigation examines a means of integrating high-performance ZnO piezoelectric thin films with a flexible stainless steel substrate (SUS304) to fabricate a double-sided piezoelectric transducer for vibration-energy harvesting applications. The double-sided piezoelectric transducer is constructed by depositing ZnO piezoelectric thin films on both the front and the back sides of the SUS304 substrate. The titanium and platinum layers were deposited using a dual-gun DC sputtering system between the ZnO piezoelectric thin film and the back side of the SUS304 substrate. The scanning electron microscopy and X-ray diffraction of ZnO piezoelectric films reveal a rigid surface structure and a highly c-axis-preferring orientation. To fabricate a transducer with a low resonant frequency, a tip-mass of 0.5 g and a vibration-area of 1 cm{sup 2} are designed, based on the cantilever vibration theory. The maximum open circuit voltage of the power transducer is approximately 18 V. After rectification and filtering through a 33 nF capacitor, a specific power output of 1.31 μW/cm{sup 2} is obtained from the transducers with a load resistance of 6 MΩ. The variation of the power output of ± 0.001% is obtained after 24-hour continuous test. - Highlights: ► A double-sided piezoelectric transducer is fabricated with the ZnO thin films. ► Vibrated frequency of a double-sided transducer is designed and presented. ► A maximum output power of 3.23 μW/cm{sup 2} is obtained under turbulent vibration.

  13. Design, Simulation and Experimental Evaluation of Tri-Phasic Piezoelectric Composite Transducers

    Science.gov (United States)

    Tamez, Juan Pedro

    Piezoelectric ceramics exhibit excellent piezoelectric and dielectric properties that is the basis of practically all transducers and piezoelectric devices, but their inherent properties, such as brittleness, non-ductility and poor shapeability may limit their applications in areas such as vibration sensing, impact detection, structural health monitoring and other reinforced structures and energy harvesting. To compensate for such limitations, the 1-3 piezoelectric composites transducers have become the material of choice for many high performance ultrasound transducers since it was invented in the late 1970's [ref. Newnham/Cross]. Extensive studies on 1-3 composites have been performed since then to improve the performance of a transducer by modifying their electromechanical coupling, bandwidth, quality factor, and flexibility and by reducing or eliminating the cross talk, i.e., induced noise between the active piezoelectric elements, especially in high power and low frequency applications. These fundamental issues, their possible solutions and their wide impact underline the motivation of the current work in this dissertation report. The motivation for this dissertation was to study and provide a foundation to designing multiphasic piezoelectric transducers that could be useful for multitude of applications. The goal was to improve the 1-3 diphasic composite transducer by eliminating the cross talk between the active piezoelectric elements while maintaining and improving the figures of merit of the design. To achieve the ultimate goal, the steps outlined below were followed: i. Understanding the theoretical and mathematical modeling for tri-phasic piezoelectric composite. ii. Implement Finite Element Analysis (FEA) and simulations of tri-phasic piezoelectric composites where the different active piezoelectric material PZT-5H and PMN-30%PT is surrounded by a vacuum phase that is enclosed by a hexagonal polymer walls. iii. Propose a redesign of the tri

  14. ACT listening test[Active transducers

    Energy Technology Data Exchange (ETDEWEB)

    Agerkvist, F. [Oersted, DTU, Kgs. Lyngby (Denmark); Fenger, L.M. [Bang and Olufsen ICEPower a/s, Kgs. Lyngby (Denmark)

    2004-07-01

    This report describes the series of subjective listening that was performed in order to test the subjective quality of the integration of amplifier and loudspeaker developed in the Active transducer project. The project is a fundamental study of the loss mechanisms in loudspeakers and amplifiers. The project has resulted in new switch mode amplifier topologies with very high audio performance at a very low cost. (BA)

  15. Transducer Analysis and ATILA++ Model Development

    Science.gov (United States)

    2016-10-10

    the behavior of single crystal piezoelectric devices. OBJECTIVES To carry out this effort, a team consisting of ISEN...recording the vibration displacements on the opposite surface of the sample with a second receiving transducer. A software program is used to curve-fit the ...analysis in a loop until the desired quality of fit is achieved. 12 The technique has, in the past, been successfully used to determine

  16. Passive Mode Carbon Nanotube Underwater Acoustic Transducer

    Science.gov (United States)

    2016-09-20

    Acoustical transducer arrays can reflect a sound signal in reverse to the sender which can be used for echo location devices. [0008] In Jiang...States Patent No. 8,494,187) a sound wave generator is disclosed which includes a carbon nanotube structure and an insulating reinforcement structure... acoustic device that includes an electrode layer and a sound wave generator. The sound wave generator is disposed on a surface of the electrode

  17. Thermoelectric Transducer Using Bio Nano Process

    Science.gov (United States)

    2015-08-01

    Ferritin; Thermal Transducer; Nanoparticle; Ammonium acetate; Separation distance; Debye length . ABSTRACT: As an application to thermos...condition of 10 mM concentration, the Debye length of ferritin is shorter than 3 nm 40 . Comparing it with the DLS results (Fig. 3), the Debye length is...modified PEGs will obstruct additional modification. This effect should strengthen when PEG length becomes longer which means the utilization of

  18. Cooling Acoustic Transducer with Heat Pipes

    Science.gov (United States)

    2009-07-29

    a heat sink. [0009] In Kan et al (United States Patent No. 6,528,909), a spindle motor assembly is disclosed which has a shaft with an integral...heat pipe. The shaft with the integral heat pipe improves the thermal conductively of the shaft and the spindle motor assembly. The shaft includes...Description of the Prior Art [0004] It is known in the art that transducers, designed to project acoustic power, are often limited by the build

  19. Turbine transducer developed for adverse conditions

    International Nuclear Information System (INIS)

    Cooper, D.R.; Edson, J.L.

    1982-01-01

    This paper reviews the latest developments that the Idaho National Engineering Laboratory (INEL) has made on a turbine transducer used in measurement of two-phase flow. It is operated in a modular configuration with a drag transducer to provide mass flow data. Current configurations allow its use in single modules or in multiples to provide flow profile information. The turbine can also provide mass flow data when used with associated instrumentation such as a densitometer. The transducer, which is the product of long investigations and test series, is subject to high vibration loading and high temperatures as well as a borated liquid environment; flow conditions range from all liquid to all steam and from ambient temperatures to over 600 0 F at pressures up to 2200 psi. Graphite bearing and carbide shaft materials were selected to provide corrosion resistance along with mechanical integrity, and resistance to wear. The new turbine design has met all operational requirements in actual use and in extended lifetime tests

  20. Stress Sensors and Signal Transducers in Cyanobacteria

    Science.gov (United States)

    Los, Dmitry A.; Zorina, Anna; Sinetova, Maria; Kryazhov, Sergey; Mironov, Kirill; Zinchenko, Vladislav V.

    2010-01-01

    In living cells, the perception of environmental stress and the subsequent transduction of stress signals are primary events in the acclimation to changes in the environment. Some molecular sensors and transducers of environmental stress cannot be identified by traditional and conventional methods. Based on genomic information, a systematic approach has been applied to the solution of this problem in cyanobacteria, involving mutagenesis of potential sensors and signal transducers in combination with DNA microarray analyses for the genome-wide expression of genes. Forty-five genes for the histidine kinases (Hiks), 12 genes for serine-threonine protein kinases (Spks), 42 genes for response regulators (Rres), seven genes for RNA polymerase sigma factors, and nearly 70 genes for transcription factors have been successfully inactivated by targeted mutagenesis in the unicellular cyanobacterium Synechocystis sp. PCC 6803. Screening of mutant libraries by genome-wide DNA microarray analysis under various stress and non-stress conditions has allowed identification of proteins that perceive and transduce signals of environmental stress. Here we summarize recent progress in the identification of sensory and regulatory systems, including Hiks, Rres, Spks, sigma factors, transcription factors, and the role of genomic DNA supercoiling in the regulation of the responses of cyanobacterial cells to various types of stress. PMID:22294932

  1. Production of particulates from transducer erosion: implications on food safety.

    Science.gov (United States)

    Mawson, Raymond; Rout, Manoj; Ripoll, Gabriela; Swiergon, Piotr; Singh, Tanoj; Knoerzer, Kai; Juliano, Pablo

    2014-11-01

    The formation of metallic particulates from erosion was investigated by running a series of transducers at various frequencies in water. Two low frequency transducer sonotrodes were run for 7.5h at 18kHz and 20kHz. Three high frequency plates operating at megasonic frequencies of 0.4MHz, 1MHz, and 2MHz were run over a 7days period. Electrical conductivity and pH of the solution were measured before and after each run. A portion of the non-sonicated and treated water was partially evaporated to achieve an 80-fold concentration of particles and then sieved through nano-filters of 0.1μm, 0.05μm, and 0.01μm. An aliquot of the evaporated liquid was also completely dried on strips of carbon tape to determine the presence of finer particles post sieving. An aliquot was analyzed for detection of 11 trace elements by Inductively Coupled Plasma Mass Spectroscopy (ICPMS). The filters and carbon tapes were analyzed by FE-SEM imaging to track the presence of metals by EDS (Energy Dispersive Spectroscopy) and measure the particle size and approximate composition of individual particles detected. Light microscopy visualization was used to calculate the area occupied by the particles present in each filter and high resolution photography was used for visualization of sonotrode surfaces. The roughness of all transducers before and after sonication was tested through profilometry. No evidence of formation of nano-particles was found at any tested frequency. High amounts of metallic micron-sized particles at 18kHz and 20kHz formed within a day, while after 7day runs only a few metallic micro particles were detected above 0.4MHz. Erosion was corroborated by an increase in roughness in the 20kHz tip after ultrasound. The elemental analysis showed that metal leach occurred but values remained below accepted drinking water limits, even after excessively long exposure to ultrasound. With the proviso that the particles measured here were only characterized in two dimensions and could be

  2. Unbinding pathway energy of glyphosate from the EPSPs enzyme binding site characterized by Steered Molecular Dynamics and Potential of Mean Force.

    Science.gov (United States)

    Ferreira, Moacir F; Franca, Eduardo F; Leite, Fábio L

    2017-03-01

    The quantification of herbicides in the environment, like glyphosate, is extremely important to prevent contamination. Nanobiosensors stands out in the quantization process, because of the high selectivity, sensitivity and short response time of the method. In order to emulate the detection of glyphosate using a specific nanobiossensor through an Atomic Force Microscope (AFM), this work carried out Steered Molecular Dynamics simulations (SMD) in which the herbicide was unbinded from the active site of the enzyme 5- enolpyruvylshikimate 3 phosphate synthase (EPSPS) along three different directions.After the simulations, Potential of Mean Force calculations were carried, from a cumulant expansion of Jarzynski's equation to obtain the profile of free energy of interaction between the herbicide and the active site of the enzyme in the presence of shikimate-3 substrate phosphate (S3P). The set of values for external work, had a Gaussian distribution. The PMF values ranged according to the directions of the unbindong pahway of each simulation, displaying energy values of 10.7, 14.7 and 19.5KJmol -1 . The results provide a theoretical support in order to assist the construction of a specific nanobiossensor to quantify the glyphosate herbicide. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Phenomenally High Transduction Air/gas Transducers for Practical Non-Contact Ultrasonic Applications

    Science.gov (United States)

    Bhardwaj, Mahesh C.

    2009-03-01

    Based on novel acoustic impedance matching layers and high coupling piezoelectric materials this paper describes exceptionally high air/gas transduction ultrasonic transducers. By providing applications oriented performance of these transducers we also usher in the era of much desired Non-Contact Ultrasound (NCU) testing and analysis of a wide range of materials including early stage formation of materials such as uncured composite prepregs, green ceramics and powder metals, plastics, elastomers, porous, hygroscopic, chemically bonded and other materials. Besides quality control, ultimately NCU offers timely opportunities for cost-effective materials production, energy savings, and environment protection.

  4. Ultrasonic properties of all-printed piezoelectric polymer transducers

    Science.gov (United States)

    Wagle, Sanat; Decharat, Adit; Bodö, Peter; Melandsø, Frank

    2013-12-01

    The ability of producing ultrasonic transducers from screen-printing has been explored experimentally, through printing and characterization of a large number of transducers. In an all-printed test design, 124 transducers with four different electrode sizes ranging from 1 to 4.9 mm2, were printed layer-by-layer on a high performance polyethyleneimine polymer. Inks from ferroelectric and conductive polymers were applied to the active part of a transducer, to provide a good acoustical match between the individual layers. Ultrasonic characterizations of the transducers done by two independent methods provided a broad-banded frequency response with a maximum response around 100 MHz.

  5. Multi-relaxation-time lattice Boltzmann modeling of the acoustic field generated by focused transducer

    Science.gov (United States)

    Shan, Feng; Guo, Xiasheng; Tu, Juan; Cheng, Jianchun; Zhang, Dong

    The high-intensity focused ultrasound (HIFU) has become an attractive therapeutic tool for the noninvasive tumor treatment. The ultrasonic transducer is the key component in HIFU treatment to generate the HIFU energy. The dimension of focal region generated by the transducer is closely relevant to the safety of HIFU treatment. Therefore, it is essential to numerically investigate the focal region of the transducer. Although the conventional acoustic wave equations have been used successfully to describe the acoustic field, there still exist some inherent drawbacks. In this work, we presented an axisymmetric isothermal multi-relaxation-time lattice Boltzmann method (MRT-LBM) model with the Bouzidi-Firdaouss-Lallemand (BFL) boundary condition in cylindrical coordinate system. With this model, some preliminary simulations were firstly conducted to determine a reasonable value of the relaxation parameter. Then, the validity of the model was examined by comparing the results obtained with the LBM results with the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation and the Spheroidal beam equation (SBE) for the focused transducers with different aperture angles, respectively. In addition, the influences of the aperture angle on the focal region were investigated. The proposed model in this work will provide significant references for the parameter optimization of the focused transducer for applications in the HIFU treatment or other fields, and provide new insights into the conventional acoustic numerical simulations.

  6. Research on Effective Electric-Mechanical Coupling Coefficient of Sandwich Type Piezoelectric Ultrasonic Transducer Using Bending Vibration Mode

    Directory of Open Access Journals (Sweden)

    Qiang Zhang

    2015-01-01

    Full Text Available An analytical model on electromechanical coupling coefficient and the length optimization of a bending piezoelectric ultrasonic transducer are proposed. The piezoelectric transducer consists of 8 PZT elements sandwiched between four thin electrodes, and the PZT elements are clamped by a screwed connection between fore beam and back beam. Firstly, bending vibration model of the piezoelectric transducer is built based on the Timoshenko beam theory. Secondly, the analytical model of effective electromechanical coupling coefficient is built based on the bending vibration model. Energy method and electromechanical equivalent circuit method are involved in the modelling process. To validate the analytical model, sandwich type piezoelectric transducer example in second order bending vibration mode is analysed. Effective electromechanical coupling coefficient of the transducer is optimized with simplex reflection technique, and the optimized ratio of length of the transducers is obtained. Finally, experimental prototypes of the sandwich type piezoelectric transducers are fabricated. Bending vibration mode and impedance of the experimental prototypes are tested, and electromechanical coupling coefficient is obtained according to the testing results. Results show that the analytical model is in good agreement with the experimental model.

  7. Long-term exposure of the isopod Porcellionides pruinosus to nickel: Costs in the energy budget and detoxification enzymes.

    Science.gov (United States)

    Ferreira, Nuno G C; Cardoso, Diogo N; Morgado, Rui; Soares, Amadeu M V M; Loureiro, Susana

    2015-09-01

    Terrestrial isopods from the species Porcellionides pruinosus were exposed to the maximum allowed nickel concentration in the Canadian framework guideline (50 mg Ni/kg soil) and to 5× this concentration (250 mg Ni/kg soil). The exposure lasted for 28 days and was followed by a recovery period of 14 days where organisms were changed to clean soil. Organisms were sampled after 24 h, 48 h, 96 h, 7 days, 14 days, 21 days, and 28 days of exposure, and at days 35 and 42 during the recovery period. For each sampling time the acetylcholinesterase (AChE), glutathione-S-transferases (GST), catalase (CAT), lactate dehydrogenase (LDH) activities were determined as well as lipid peroxidation rate (LPO) along with lipids, carbohydrates, proteins content, energy available (Ea), energy consumption (Ec) and cellular energy allocation (CEA). The integrated biomarker response (IBR) was calculated for each sampling time as well as for each one of the above parameters. In addition, mortality was also recorded throughout the assay. The results obtained showed that nickel induced oxidative stress, evidenced by results on GST, GPx, CAT or LPO, but also on changes in the energy reserves content of these organisms. In addition, this study showed that these organisms possess a specific strategy to handle nickel toxicity. In this case, biomarkers were associated with costs in the energy budget, and the increase of energy reserves has a compensation for that cost. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Linear Array Ultrasonic Transducers: Sensitivity and Resolution Study

    International Nuclear Information System (INIS)

    Kramb, V.A.

    2005-01-01

    The University of Dayton Research Institute (UDRI) under contract by the US Air Force has designed and integrated a fully automated inspection system for the inspection of turbine engines that incorporates linear phased array ultrasonic transducers. Phased array transducers have been successfully implemented into weld and turbine blade root inspections where the defect types are well known and characterized. Embedded defects in aerospace turbine engine components are less well defined, however. In order to determine the applicability of linear arrays to aerospace inspections the sensitivity of array transducers to embedded defects in engine materials must be characterized. In addition, the implementation of array transducers into legacy inspection procedures must take into account any differences in sensitivity between the array transducer and that of the single element transducer currently used. This paper discusses preliminary results in a study that compares the sensitivity of linear array and conventional single element transducers to synthetic hard alpha defects in a titanium alloy

  9. Förster resonance energy transfer demonstrates a flavonoid metabolon in living plant cells that displays competitive interactions between enzymes

    NARCIS (Netherlands)

    Crosby, K.C.; Pietraszewska-Bogiel, A.; Gadella (jr.), T.W.J.; Winkel, B.S.J.

    2011-01-01

    We have used Förster resonance energy transfer detected by fluorescence lifetime imaging microscopy (FLIM-FRET) to provide the first evidence from living plants cells for the existence of a flavonoid metabolon. The distribution of flux within this system may be regulated by the direct competition of

  10. Na, K-ATPase as signaling transducer

    OpenAIRE

    Li, Juan

    2007-01-01

    It is now generally agreed that Na,K-ATPase (NKA), in addition to its role in the maintenance of Na+ and K+ gradients across the cell membrane, is a signal transducer. Our group has identified a novel signaling pathway where NKA interact with IP3R to form a signaling microdomain. Ouabain, a specific ligand of NKA, activates this pathway, triggers slow Ca2+ oscillations and activates NF-κB. In current study, the molecular mechanisms and some important downstream effects of NK...

  11. Modeling of nonlinear responses for reciprocal transducers involving polarization switching

    DEFF Research Database (Denmark)

    Willatzen, Morten; Wang, Linxiang

    2007-01-01

    Nonlinearities and hysteresis effects in a reciprocal PZT transducer are examined by use of a dynamical mathematical model on the basis of phase-transition theory. In particular, we consider the perovskite piezoelectric ceramic in which the polarization process in the material can be modeled...... by Landau theory for the first-order phase transformation, in which each polarization state is associated with a minimum of the Landau free-energy function. Nonlinear constitutive laws are obtained by using thermodynamical equilibrium conditions, and hysteretic behavior of the material can be modeled...... intrinsically. The time-dependent Ginzburg-Landau theory is used in the parameter identification involving hysteresis effects. We use the Chebyshev collocation method in the numerical simulations. The elastic field is assumed to be coupled linearly with other fields, and the nonlinearity is in the E-D coupling...

  12. Towards a visual modeling approach to designing microelectromechanical system transducers

    Science.gov (United States)

    Dewey, Allen; Srinivasan, Vijay; Icoz, Evrim

    1999-12-01

    In this paper, we address initial design capture and system conceptualization of microelectromechanical system transducers based on visual modeling and design. Visual modeling frames the task of generating hardware description language (analog and digital) component models in a manner similar to the task of generating software programming language applications. A structured topological design strategy is employed, whereby microelectromechanical foundry cell libraries are utilized to facilitate the design process of exploring candidate cells (topologies), varying key aspects of the transduction for each topology, and determining which topology best satisfies design requirements. Coupled-energy microelectromechanical system characterizations at a circuit level of abstraction are presented that are based on branch constitutive relations and an overall system of simultaneous differential and algebraic equations. The resulting design methodology is called visual integrated-microelectromechanical VHDL-AMS interactive design (VHDL-AMS is visual hardware design language for analog and mixed signal).

  13. Comparative study on effects of four energy plants growth on chemical fractions of heavy metals and activity of soil enzymes in copper mine tailings.

    Science.gov (United States)

    Zhang, Jie; Yang, Shiyong; Yang, Hongfei; Huang, Yongjie; Zheng, Liming; Yuan, Jing; Zhou, Shoubiao

    2018-05-12

    Four gramineous energy plants, Miscanthus sacchariflorus, M. floridulus, Phragmites australis, and Arundo donax were grown on copper tailings in the field for four years. Their phytoremediation potential was examined in terms of their effects on the fractions of heavy metals and soil enzyme activities. Results showed that plantation of these four gramineous plants has improved the proportion of organic material (OM)-binding fraction of heavy metals in copper tailings as a whole, and reduced the proportion of exchangeable and residual fractions. In particular, M. sacchariflorus growth improved significantly the proportion of the OM-binding fractions of Cu (1.73 times), Cd (1.71 times), Zn (1.18 times), and Pb (3.14 times) (P tailings to some extent. In particular, the activity of soil phosphatase and urease in planted tailings differed significantly from that of control (P tailings.

  14. A new concept of smart flexible phased array transducer to inspect component of complex geometry

    International Nuclear Information System (INIS)

    Roy, O.; Mauhaut, S.; Casula, O.; Cattiaux, G.

    2001-01-01

    In most of industries as aeronautics, aerospace and nuclear, the main part of the non destructive testing is carried out directly in touch with the inspected component. Among others, the cooling piping of French pressurized water reactor comprises many welding components with complex geometry: elbows, butt welds, nozzles. In service inspections of such components performed with conventional ultrasonic contact transducers present limited performances. First, variations in sensitivity, due to unmatched contact on depressions or irregular surface are observed, resulting in poor detection performances. In addition, the beam orientation transmitted through complex interfaces cannot be totally controlled, because of the disorientations suffered by the transducer during its displacement. As a result, the possible defect cannot be correctly detected, positioned and characterized. To overcome these difficulties and to improve the performances of such inspections, the French Atomic Energy Commission has developed a new concept of transducer, allowing both to take into account the varying profile of the tested component and to efficiently compensate these effects. This transducer is a flexible phased array able to match the surface of the inspected specimen and to efficiently compensate the deformation of its own surface, in order to preserve the ultrasonic beam characteristics in spite of the profile variations encountered during the scanning. This ability is achieved thanks to a specific instrumentation, which measures the deformation of the transducer radiating surface, made of individual ultrasonic elements mechanically jointed to fit the actual surface of the component being inspected. Inspections in pulse-echo mode have been performed on a specimen with an irregular profile containing artificial embedded reflectors. The comparison with inspection carried out using conventional transducer shows the efficiency of the system to characterize defects under such complex

  15. Manufacturing technologies for ultrasonic transducers in a broad frequency range

    OpenAIRE

    Gebhardt, Sylvia; Hohlfeld, Kai; Günther, Paul; Neubert, Holger

    2018-01-01

    According to the application field, working frequency of ultrasonic transducers needs to be tailored to a certain value. Low frequency ultrasonic transducers with working frequencies of 1 kHz to 1 MHz are especially interesting for sonar applications, whereas high frequency ultrasonic transducers with working frequencies higher than 15 MHz are favorable for high-resolution imaging in biomedical and non-destructive evaluation. Conventional non-destructive testing devices and clinical ultrasoun...

  16. High Temperature Ultrasonic Transducer for Real-time Inspection

    Science.gov (United States)

    Amini, Mohammad Hossein; Sinclair, Anthony N.; Coyle, Thomas W.

    A broadband ultrasonic transducer with a novel porous ceramic backing layer is introduced to operate at 700 °C. 36° Y-cut lithium niobate (LiNbO3) single crystal was selected for the piezoelectric element. By appropriate choice of constituent materials, porosity and pore size, the acoustic impedance and attenuation of a zirconia-based backing layer were optimized. An active brazing alloy with high temperature and chemical stability was selected to bond the transducer layers together. Prototype transducers have been tested at temperatures up to 700 °C. The experiments confirmed that transducer integrity was maintained.

  17. FEM Modeling of a Magnetoelectric Transducer for Autonomous Micro Sensors in Medical Application

    Science.gov (United States)

    Yang, Gang; Talleb, Hakeim; Gensbittel, Aurélie; Ren, Zhuoxiang

    2015-11-01

    In the context of wireless and autonomous sensors, this paper presents the multiphysics modeling of an energy transducer based on magnetoelectric (ME) composite for biomedical applications. The study considers the power requirement of an implanted sensor, the communication distance, the size limit of the device for minimal invasive insertion as well as the electromagnetic exposure restriction of the human body. To minimize the electromagnetic absorption by the human body, the energy source is provided by an external reader emitting low frequency magnetic field. The modeling is carried out with the finite element method by solving simultaneously the multiple physics problems including the electric load of the conditioning circuit. The simulation results show that with the T-L mode of a trilayer laminated ME composite, the transducer can deliver the required energy in respecting different constraints.

  18. Biochemical characterization of thermostable cellulase enzyme from ...

    African Journals Online (AJOL)

    user

    2012-05-29

    May 29, 2012 ... tested for their ability to produce cellulase complex enzyme by growing on a defined substrates as well ... In the current industrial processes, cellulolytic enzymes ... energy sources such as glucose, ethanol, hydrogen and.

  19. High-Temperature Surface-Acoustic-Wave Transducer

    Science.gov (United States)

    Zhao, Xiaoliang; Tittmann, Bernhard R.

    2010-01-01

    Aircraft-engine rotating equipment usually operates at high temperature and stress. Non-invasive inspection of microcracks in those components poses a challenge for the non-destructive evaluation community. A low-profile ultrasonic guided wave sensor can detect cracks in situ. The key feature of the sensor is that it should withstand high temperatures and excite strong surface wave energy to inspect surface/subsurface cracks. As far as the innovators know at the time of this reporting, there is no existing sensor that is mounted to the rotor disks for crack inspection; the most often used technology includes fluorescent penetrant inspection or eddy-current probes for disassembled part inspection. An efficient, high-temperature, low-profile surface acoustic wave transducer design has been identified and tested for nondestructive evaluation of structures or materials. The development is a Sol-Gel bismuth titanate-based surface-acoustic-wave (SAW) sensor that can generate efficient surface acoustic waves for crack inspection. The produced sensor is very thin (submillimeter), and can generate surface waves up to 540 C. Finite element analysis of the SAW transducer design was performed to predict the sensor behavior, and experimental studies confirmed the results. One major uniqueness of the Sol-Gel bismuth titanate SAW sensor is that it is easy to implement to structures of various shapes. With a spray coating process, the sensor can be applied to surfaces of large curvatures. Second, the sensor is very thin (as a coating) and has very minimal effect on airflow or rotating equipment imbalance. Third, it can withstand temperatures up to 530 C, which is very useful for engine applications where high temperature is an issue.

  20. Smooth driving of Moessbauer electromechanical transducers

    Energy Technology Data Exchange (ETDEWEB)

    Veiga, A., E-mail: veiga@fisica.unlp.edu.ar; Mayosky, M. A. [Universidad Nacional de La Plata, Facultad de Ingenieria (Argentina); Martinez, N.; Mendoza Zelis, P.; Pasquevich, G. A.; Sanchez, F. H. [Instituto de Fisica La Plata, CONICET (Argentina)

    2011-11-15

    Quality of Moessbauer spectra is strongly related to the performance of source velocity modulator. Traditional electromechanical driving techniques demand hard-edged square or triangular velocity waveforms that introduce long settling times and demand careful driver tuning. For this work, the behavior of commercial velocity transducers and drive units was studied under different working conditions. Different velocity reference waveforms in constant-acceleration, constant-velocity and programmable-velocity techniques were tested. Significant improvement in spectrometer efficiency and accuracy was achieved by replacing triangular and square hard edges with continuous smooth-shaped transitions. A criterion for best waveform selection and synchronization is presented and attainable enhancements are evaluated. In order to fully exploit this driving technique, a compact microprocessor-based architecture is proposed and a suitable data acquisition system implementation is presented. System linearity and efficiency characterization are also shown.

  1. Modeling piezoelectric ultrasonic transducers for physiotherapy

    International Nuclear Information System (INIS)

    Iglesias, E.; Frutos, J. de; Montero de Espinosa, F.

    2015-01-01

    Applications of ultrasound are well known in medical and aesthetic skin and subcutaneous fatty tissue mobilization treatments. The basic transducer used consists of a piezoelectric disk adhered to a metal delay line in capsule shape. The capsule design is critical since the two bonded elements have vibration modes which can cause very inefficient designs and vibration distributions very irregular if they are not properly studied and utilized. This must be known to avoid distributions of heat and sound pressure that could be ineffective or harmful. In this paper, using Finite Element Method and laser interferometric vibrational analysis, it has reached a piston-type solution that allows properly implement sound pressure vibration dose. (Author)

  2. Development of piezoelectric composites for transducers

    Science.gov (United States)

    Safari, A.

    1994-07-01

    For the past decade and a half, many different types of piezoelectric ceramic-polymer composites have been developed intended for transducer applications. These diphasic composites are prepared from non-active polymer, such as epoxy, and piezoelectric ceramic, such as PZT, in the form of filler powders, elongated fibers, multilayer and more complex three-dimensional structures. For the last four years, most of the efforts have been given to producing large area and fine scale PZT fiber composites. In this paper, processing of piezoelectric ceramic-polymer composites with various connectivity patterns are reviewed. Development of fine scale piezoelectric composites by lost mold, injection molding and the relic method are described. Research activities of different groups for preparing large area piezocomposites for hydrophone and actuator applications are briefly reviewed. Initial development of electrostrictive ceramics and composites are also

  3. Design optimization of embedded ultrasonic transducers for concrete structures assessment.

    Science.gov (United States)

    Dumoulin, Cédric; Deraemaeker, Arnaud

    2017-08-01

    In the last decades, the field of structural health monitoring and damage detection has been intensively explored. Active vibration techniques allow to excite structures at high frequency vibrations which are sensitive to small damage. Piezoelectric PZT transducers are perfect candidates for such testing due to their small size, low cost and large bandwidth. Current ultrasonic systems are based on external piezoelectric transducers which need to be placed on two faces of the concrete specimen. The limited accessibility of in-service structures makes such an arrangement often impractical. An alternative is to embed permanently low-cost transducers inside the structure. Such types of transducers have been applied successfully for the in-situ estimation of the P-wave velocity in fresh concrete, and for crack monitoring. Up to now, the design of such transducers was essentially based on trial and error, or in a few cases, on the limitation of the acoustic impedance mismatch between the PZT and concrete. In the present study, we explore the working principles of embedded piezoelectric transducers which are found to be significantly different from external transducers. One of the major challenges concerning embedded transducers is to produce very low cost transducers. We show that a practical way to achieve this imperative is to consider the radial mode of actuation of bulk PZT elements. This is done by developing a simple finite element model of a piezoelectric transducer embedded in an infinite medium. The model is coupled with a multi-objective genetic algorithm which is used to design specific ultrasonic embedded transducers both for hard and fresh concrete monitoring. The results show the efficiency of the approach and a few designs are proposed which are optimal for hard concrete, fresh concrete, or both, in a given frequency band of interest. Copyright © 2017 Elsevier B.V. All rights reserved.

  4. Resonant acoustic transducer system for a well drilling string

    Science.gov (United States)

    Nardi, Anthony P.

    1981-01-01

    For use in transmitting acoustic waves propated along a well drilling string, a piezoelectric transducer is provided operating in the relatively low loss acoustic propagation range of the well drilling string. The efficiently coupled transmitting transducer incorporates a mass-spring-piezoelectric transmitter combination permitting a resonant operation in the desired low frequency range.

  5. Resonant transducers for solid-state plasma density modulation

    Energy Technology Data Exchange (ETDEWEB)

    Hallock, Gary A., E-mail: hallock@ece.utexas.edu [The University of Texas at Austin, Austin, Texas 78701 (United States); Meier, Mark A., E-mail: mark.a.meier@exxonmobil.com [ExxonMobil Upstream Research Company, Houston, Texas 77389 (United States)

    2016-04-15

    We have developed transducers capable of modulating the plasma density and plasma density gradients in indium antimonide. These transducers make use of piezoelectric drivers to excite acoustic pressure resonance at 3λ/2, generating large amplitude standing waves and plasma density modulations. The plasma density has been directly measured using a laser diagnostic. A layered media model shows good agreement with the experimental measurements.

  6. Optimization of ultrasonic tube testing with concentric transducers

    International Nuclear Information System (INIS)

    Dufayet, J.-P.; Gambin, Raymond.

    1978-01-01

    In order to test tubes by ultrasonics without rotation, concentric transducers can be used with conical mirrors to detect transverse defects and with helical shaped mirrors to detect longitudinal defects. Further optimization studies have been carried out in order to bring the system highly operational. The respective advantages brought by the rotating screen or by our especially designed sectorial transducers are discussed [fr

  7. Respiratory Belt Transducer Constructed Using a Singing Greeting Card Beeper

    Science.gov (United States)

    Bhaskar, Anand; Subramani, Selvam; Ojha, Rajdeep

    2013-01-01

    An article by Belusic and Zupancic described the construction of a finger pulse sensor using a singing greeting card beeper. These authors felt that this beeper made of piezoelectric material could be easily modified to function as a respiratory belt transducer to monitor respiratory movements. Commercially available respiratory belt transducers,…

  8. Design and performance of the drag-disc turbine transducer

    International Nuclear Information System (INIS)

    Averill, R.H.; Goodrich, L.D.; Ford, R.E.

    1979-01-01

    Mass flow rates at the Loss-of-Fluid Test (LOFT) facility, EG and G Idaho, Inc., at the Idaho National Engineering Laboratory, are measured with the drag-disc turbine transducer (DTT). Operational description of the DTT and the developmental effort are discussed. Performance data and experiences with this transducer have been evaluated and are presented in this paper

  9. A mathematical model for transducer working at high temperature

    International Nuclear Information System (INIS)

    Fabre, J.P.

    1974-01-01

    A mathematical model is proposed for a lithium niobate piezoelectric transducer working at high temperature in liquid sodium. The model proposed suitably described the operation of the high temperature transducer presented; it allows the optimization of the efficiency and band-pass [fr

  10. A Force Transducer from a Junk Electronic Balance

    Science.gov (United States)

    Aguilar, Horacio Munguia; Aguilar, Francisco Armenta

    2009-01-01

    It is shown how the load cell from a junk electronic balance can be used as a force transducer for physics experiments. Recovering this device is not only an inexpensive way of getting a valuable laboratory tool but also very useful didactic work on electronic instrumentation. Some experiments on mechanics with this transducer are possible after a…

  11. Transducer hygiene: comparison of procedures for decontamination of ultrasound transducers and their use in clinical practice.

    Science.gov (United States)

    Häggström, Mikael; Spira, Jack; Edelstam, Greta

    2015-02-01

    To determine whether current hygiene practices are appropriate during sonographic examinations. Five major hospitals in Sweden were investigated with a survey. At each hospital, the departments corresponding to the main types of sonographic examination were chosen. Personnel who were responsible for or acquainted with the local hygiene procedures completed a standardardized questionnaire. The surveys were completed by 25 departments, where the total number of sonographic examinations was approximately 20,000 per month. For transvaginal and transrectal sonographic examinations, the most common method for decontamination of the transducer was barrier protection during the procedure followed by cleansing with alcohol. Latex was the predominant cover material, but one department used polyethylene gloves, and another department used nitrile gloves. Both of these involved transvaginal ultrasonography. In transcutaneous examinations, all hospitals were using alcohol and paper or cloth for decontamination at a minimum. Transesophageal examinations were carried out without barrier protection, and decontamination was performed with an alkylating substance. The hygiene practices appear to be appropriate at most hospitals, but there is a prevalence of transducer cover materials of unacceptable permeability, as well as use of gloves on transducers despite insufficient evidence of safety. © 2015 Wiley Periodicals, Inc.

  12. DGAT enzymes and triacylglycerol biosynthesis

    Science.gov (United States)

    Yen, Chi-Liang Eric; Stone, Scot J.; Koliwad, Suneil; Harris, Charles; Farese, Robert V.

    2008-01-01

    Triacylglycerols (triglycerides) (TGs) are the major storage molecules of metabolic energy and FAs in most living organisms. Excessive accumulation of TGs, however, is associated with human diseases, such as obesity, diabetes mellitus, and steatohepatitis. The final and the only committed step in the biosynthesis of TGs is catalyzed by acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes. The genes encoding two DGAT enzymes, DGAT1 and DGAT2, were identified in the past decade, and the use of molecular tools, including mice deficient in either enzyme, has shed light on their functions. Although DGAT enzymes are involved in TG synthesis, they have distinct protein sequences and differ in their biochemical, cellular, and physiological functions. Both enzymes may be useful as therapeutic targets for diseases. Here we review the current knowledge of DGAT enzymes, focusing on new advances since the cloning of their genes, including possible roles in human health and diseases. PMID:18757836

  13. Design and Development of transducer for IR radiation measurement

    International Nuclear Information System (INIS)

    Pattarachindanuwong, Surat; Poopat, Bovornchoke; Meethong, Wachira

    2003-06-01

    Recently, IR radiation has many important roles such as for plastics industry, food industry and medical instrumentation. The consequence of exposed irradiation objects from IR can be greatly affected by the quantity of IR radiation. Therefore the objectively this research is to design and develop a transducer for IR radiation measurement. By using a quartz halogen lamp as a IR heat source of IR radiation and a thermopile sensor as a transducer. The thermal conductivity of transducer and air flow, were also considered for design and development of transducer. The study shows that the designed transducer can be used and applied in high temperature process, for example, the quality control of welding, the non-contact temperature measurement of drying oven and the testing of IR source in medical therapy device

  14. Transducers for Sound and Vibration - FEM Based Design

    DEFF Research Database (Denmark)

    Liu, Bin

    2001-01-01

    Design of transducers for measurement of vibration (piezoelectric accelerometers) and sound (condenser microphones) is a very labour intensive work. The design work is mostly based on experience and on simple analogies to electrical circuit design. Often a time consuming itterative loop is used......: Specification of the transducer, production of a physical prototype, measurements on the prototype, changed specification of the transducer etc. Furthermore are many transducers made based on customer requirements which also increases the amount of required design work. For these reasons there is a need...... for methods that can reduce the design time consumption and the number of itterations. The present work proposes to use finite element based programs for simulating the behaviour of a transducer with a given set of specifications. A simulation program for accelerometers was developed and has been tested...

  15. Photoacoustic imaging of early gastric cancer diagnosis based on long focal area ultrasound transducer

    Science.gov (United States)

    Wu, Huaqin; Li, Zuoran; Liu, Lantian; Li, Zhifang; Wu, Shulian; Li, Hui

    2017-06-01

    We illustrated a novel imaging method to diagnose gastric neoplasms via photoacoustic tomography (PAT). Depending on the structural characteristics of gastric cavity, we used column diffusion fiber to irradiate the stomach tissue through the esophagus, and the externally placed telecentric focus ultrasonic transducer detected photoacoustic signals from the gastric tissue. We reconstructed the distribution of light energy deposition of the simulated gastric tumor, and obtained the location and size information of gastric tumor.

  16. Acoustic cavity transducers for the manipulation of cells and biomolecules

    Science.gov (United States)

    Tovar, Armando; Patel, Maulik; Lee, Abraham P.

    2010-02-01

    A novel fluidic actuator that is simple to fabricate, integrate, and operate is demonstrated for use within microfluidic systems. The actuator is designed around the use of trapped air bubbles in lateral cavities and the resultant acoustic streaming generated from an outside acoustic energy source. The orientation of the lateral cavities to the main microchannel is used to control the bulk fluid motion within the device. The first order flow generated by the oscillating bubble is used to develop a pumping platform that is capable of driving fluid within a chip. This pump is integrated into a recirculation immunoassay device for enhanced biomolecule binding through fluid flow for convection limited transport. The recirculation system showed an increase in binding site concentration when compared with traditional passive and flow-through methods. The acoustic cavity transducer has also been demonstrated for application in particle switching. Bursts of acoustic energy are used to generate a second order streaming pattern near the cavity interface to drive particles away or towards the cavity. The use of this switching mechanism is being extended to the application of sorting cells and other particles within a microfluidic system.

  17. The evolution of energy-transducing systems. Studies with archaebacteria

    Science.gov (United States)

    Stan-Lotter, Helga

    1994-01-01

    N-ethylmaleimide (NEM) inhibits the ATPase of H. saccharovorum in a nucleotide protectable manner. The bulk of C-14 NEM is incorporated into subunit one. Cyanogen bromide cleavage of labeled subunit one indicated that NEM bound to a peptide of a Mr of about 8,900. Thus, Cys 262 (H. salinarium numbering) may be the NEM binding site. Cyanogen bromide fragments have been submitted for sequencing. To prove the presence of three Cys residues in subunit one, alkaline cleavage following treatment with NTCB was carried out. Thiol reagents such as p-chloro mercuri phenyl sulfonate also inhibited the ATPase. However, this inhibition was not nucleotide-protectable, suggesting a different location and role for the PCMS-sensitive Cys. The proteolipid which was extracted with chloroform/methanol from the membranes of H. saccharovorum cross-reacted with an antiserum against subunit c (the DCCD-binding protein) of Escherichia coli. Following labeling of membranes from H. saccharovorum with C-14 DCCD under conditions, which inhibited ATP synthesis, the isotope was incorporated into one protein of Mr of about 6,500. Thus, the proteolipid of H. saccharovorum and the DCCD-labeled peptide may be identical. If so, these results suggest that the proteolipid is a component of the membrane sector of an archaeal F-type ATP synthase.

  18. The AMPK enzyme-complex: from the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders.

    Science.gov (United States)

    Antonioli, Luca; Colucci, Rocchina; Pellegrini, Carolina; Giustarini, Giulio; Sacco, Deborah; Tirotta, Erika; Caputi, Valentina; Marsilio, Ilaria; Giron, Maria Cecilia; Németh, Zoltán H; Blandizzi, Corrado; Fornai, Matteo

    2016-01-01

    Adenosine monophosphate-activated protein kinase (AMPK), known as an enzymatic complex that regulates the energetic metabolism, is emerging as a pivotal enzyme and enzymatic pathway involved in the regulation of immune homeostatic networks. It is also involved in the molecular mechanisms underlying the pathophysiology of chronic inflammatory diseases. AMPK is expressed in several immune cell types including macrophages, lymphocytes, neutrophils and dendritic cells, and governs a broad array of cell functions, which include cytokine production, chemotaxis, cytotoxicity, apoptosis and proliferation. Based on its wide variety of immunoregulatory actions, the AMPK system has been targeted to reveal its impact on the course of immune-related diseases, such as atherosclerosis, psoriasis, joint inflammation and inflammatory bowel diseases. The identification of AMPK subunits responsible for specific anti-inflammatory actions and the understanding of the underlying molecular mechanisms will promote the generation of novel AMPK activators, endowed with improved pharmacodynamic and pharmacokinetic profiles. These new tools will aid us to utilize AMPK pathway activation in the management of acute and chronic inflammatory diseases, while minimizing potential adverse reactions related to the effects of AMPK on metabolic energy.

  19. Numerical comparison of patch and sandwich piezoelectric transducers for transmitting ultrasonic waves

    CSIR Research Space (South Africa)

    Loveday, PW

    2006-03-01

    Full Text Available in the waveguide. Piezoelectric patch transducers are frequently employed, by researchers, for exciting waves in beam like structures. Sonar systems frequently make use of resonant transducers, such as sandwich transducers, for acoustic wave generation...

  20. Mechanical Amplifier for a Piezoelectric Transducer

    Science.gov (United States)

    Moore, James; Swain, Mark; Lawson, Peter; Calvet, Robert

    2003-01-01

    A mechanical amplifier has been devised to multiply the stroke of a piezoelectric transducer (PZT) intended for use at liquid helium temperatures. Interferometry holds the key to high angular resolution imaging and astrometry in space. Future space missions that will detect planets around other solar systems and perform detailed studies of the evolution of stars and galaxies will use new interferometers that observe at mid- and far-infrared wavelengths. Phase-measurement interferometry is key to many aspects of astronomical interferometry, and PZTs are ideal modulators for most methods of phase measurement, but primarily at visible wavelengths. At far infrared wavelengths of 150 to 300 m, background noise is a severe problem and all optics must be cooled to about 4 K. Under these conditions, piezos are ill-suited as modulators, because their throw is reduced by as much as a factor of 2, and even a wavelength or two of modulation is beyond their capability. The largest commercially available piezo stacks are about 5 in. (12.7 cm) long and have a throw of about 180 m at room temperature and only 90 m at 4 K. It would seem difficult or impossible to use PZTs for phase measurements in the far infrared were it not for the new mechanical amplifier that was designed and built.

  1. Bonding and impedance matching of acoustic transducers using silver epoxy.

    Science.gov (United States)

    Son, Kyu Tak; Lee, Chin C

    2012-04-01

    Silver epoxy was selected to bond transducer plates on glass substrates. The properties and thickness of the bonding medium affect the electrical input impedance of the transducer. Thus, the thickness of the silver epoxy bonding layer was used as a design parameter to optimize the structure for the transducer input impedance to match the 50 Ω output impedance of most radio frequency (RF) generators. Simulation and experimental results show that nearly perfect matching is achieved without using any matching circuit. At the matching condition, the transducer operates at a frequency band a little bit below the half-wavelength resonant frequency of the piezoelectric plate. In experiments, lead titanate (PT) piezoelectric plates were employed. Both full-size, 11.5 mm × 2 mm × 0.4 mm, and half-size, 5.75 mm × 2 mm × 0.4 mm, can be well matched using optimal silver epoxy thickness. The transducer assemblies demonstrate high efficiency. The conversion loss from electrical power to acoustic power in soda-lime glass is 4.3 dB. This loss is low considering the fact that the transducers operate at off-resonance by 12%. With proper choice of silver epoxy thickness, the transducer can be matched at the fundamental, the 3rd and 5th harmonic frequencies. This leads to the possible realization of triple-band transducers. Reliability was assessed with thermal cycling test according to Telcordia GR-468-Core recommendation. Of the 30 transducer assemblies tested, none broke until 2900 cycles and 27 have sustained beyond 4050 cycles. Copyright © 2011 Elsevier B.V. All rights reserved.

  2. Stability of Enzymes in Granular Enzyme Products for Laundry Detergents

    DEFF Research Database (Denmark)

    Biran, Suzan; Bach, Poul; Simonsen, Ole

    Enzymes have long been of interest to the detergent industry due to their ability to improve the cleaning efficiency of synthetic detergents, contribute to shortening washing times, and reduce energy and water consumption, provision of environmentally friendlier wash water effluents and fabric care....... However, incorporating enzymes in detergent formulations gives rise to numerous practical problems due to their incompatibility with and stability against various detergent components. In powdered detergent formulations, these issues can be partly overcome by physically isolating the enzymes in separate...... particles. However, enzymes may loose a significant part of their activity over a time period of several weeks. Possible causes of inactivation of enzymes in a granule may be related to the release of hydrogen peroxide from the bleaching chemicals in a moisture-containing atmosphere, humidity, autolysis...

  3. Broadband electrical impedance matching for piezoelectric ultrasound transducers.

    Science.gov (United States)

    Huang, Haiying; Paramo, Daniel

    2011-12-01

    This paper presents a systematic method for designing broadband electrical impedance matching networks for piezoelectric ultrasound transducers. The design process involves three steps: 1) determine the equivalent circuit of the unmatched piezoelectric transducer based on its measured admittance; 2) design a set of impedance matching networks using a computerized Smith chart; and 3) establish the simulation model of the matched transducer to evaluate the gain and bandwidth of the impedance matching networks. The effectiveness of the presented approach is demonstrated through the design, implementation, and characterization of impedance matching networks for a broadband acoustic emission sensor. The impedance matching network improved the power of the acquired signal by 9 times.

  4. USE OF PELTIER COOLERS AS SOIL HEAT FLUX TRANSDUCERS.

    Science.gov (United States)

    Weaver, H.L.; Campbell, G.S.

    1985-01-01

    Peltier coolers were modified and calibrated to serve as soil heat flux transducers. The modification was to fill their interiors with epoxy. The average calibration constant on 21 units was 13. 6 plus or minus 0. 8 kW m** minus **2 V** minus **1 at 20 degree C. This sensitivity is about eight times that of the two thermopile transducers with which comparisons were made. The thermal conductivity of the Peltier cooler transducers was 0. 4 W m** minus **1 degree C** minus **1, which is comparable to that of dry soil.

  5. Reflective array modeling for reflective and directional SAW transducers.

    Science.gov (United States)

    Morgan, D P

    1998-01-01

    This paper presents a new approximate method for analyzing reflective SAW transducers, with much of the convenience of the coupled-mode (COM) method but with better accuracy. Transduction accuracy is obtained by incorporating the accurate electrostatic solution, giving for example correct harmonics, and allowance for electrode width variation, in a simple manner. Results are shown for a single-electrode transducer, Natural SPUDT and DART SPUDT, each using theoretically derived parameters. In contrast to the COM, the RAM can give accurate results for short or withdrawal-weighted transducers and for wide analysis bandwidth.

  6. Ultrasonic Transducer Peak-to-Peak Optical Measurement

    Directory of Open Access Journals (Sweden)

    Pavel Skarvada

    2012-01-01

    Full Text Available Possible optical setups for measurement of the peak-to-peak value of an ultrasonic transducer are described in this work. The Michelson interferometer with the calibrated nanopositioner in reference path and laser Doppler vibrometer were used for the basic measurement of vibration displacement. Langevin type of ultrasonic transducer is used for the purposes of Electro-Ultrasonic Nonlinear Spectroscopy (EUNS. Parameters of produced mechanical vibration have to been well known for EUNS. Moreover, a monitoring of mechanical vibration frequency shift with a mass load and sample-transducer coupling is important for EUNS measurement.

  7. Advances in enzyme bioelectrochemistry

    Directory of Open Access Journals (Sweden)

    ANDRESSA R. PEREIRA

    Full Text Available ABSTRACT Bioelectrochemistry can be defined as a branch of Chemical Science concerned with electron-proton transfer and transport involving biomolecules, as well as electrode reactions of redox enzymes. The bioelectrochemical reactions and system have direct impact in biotechnological development, in medical devices designing, in the behavior of DNA-protein complexes, in green-energy and bioenergy concepts, and make it possible an understanding of metabolism of all living organisms (e.g. humans where biomolecules are integral to health and proper functioning. In the last years, many researchers have dedicated itself to study different redox enzymes by using electrochemistry, aiming to understand their mechanisms and to develop promising bioanodes and biocathodes for biofuel cells as well as to develop biosensors and implantable bioelectronics devices. Inside this scope, this review try to introduce and contemplate some relevant topics for enzyme bioelectrochemistry, such as the immobilization of the enzymes at electrode surfaces, the electron transfer, the bioelectrocatalysis, and new techniques conjugated with electrochemistry vising understand the kinetics and thermodynamics of redox proteins. Furthermore, examples of recent approaches in designing biosensors and biofuel developed are presented.

  8. Testing of Local Velocity Transducer Used at Sodium Thermal Hydraulic Test Facilities

    International Nuclear Information System (INIS)

    Kim, Tae Joon; Eoh, Jae Hyuk; Hwang, In Koo; Jeong, Ji Young; Kim, Jong Man; Lee, Yong Bum; Kim, Yeong Il

    2012-01-01

    KAERI (Korea Atomic Energy Research Institute) will perform a test for a thermal hydraulic simulation with STELLA-1 for a Component Performance Test Sodium Loop in the year 2012, and subsequently it will construct for STELLA-2 for a Sodium Thermalhydraulic Experimental Facility in the year 2016. The STELLA-2 consists of a scaled reactor vessel with a core of electric heaters, four IHXs, two PHTS pumps, two DHXs, and two AHXs. In STELLA-2, several kinds of flow measurements exists. In this paper, the local velocity transducer as a prototype tested in IPPE (in Russia), was manufactured as a prototype by a shop in KAERI. This local velocity transducer will be used to measure the flow rate in a pool

  9. Smart Drug Delivery System-Inspired Enzyme-Linked Immunosorbent Assay Based on Fluorescence Resonance Energy Transfer and Allochroic Effect Induced Dual-Modal Colorimetric and Fluorescent Detection.

    Science.gov (United States)

    Miao, Luyang; Zhu, Chengzhou; Jiao, Lei; Li, He; Du, Dan; Lin, Yuehe; Wei, Qin

    2018-02-06

    Numerous analytical techniques have been undertaken for the detection of protein biomarkers because of their extensive and significant applications in clinical diagnosis, whereas there are few strategies to develop dual-readout immunosensors to achieve more accurate results. To the best of our knowledge, inspired by smart drug delivery system (DDS), a novel pH-responsive modified enzyme-linked immunosorbent assay (ELISA) was innovatively developed for the first time, realizing dual-modal colorimetric and fluorescent detection of cardiac troponin I (cTnI). Curcumin (CUR) was elaborately selected as a reporter molecule, which played the same role of drugs in DDS based on the following considerations: (1) CUR can be used as a kind of pH indicator by the inherited allochroic effect induced by basic pH value; (2) the fluorescence of CUR can be quenched by certain nanocarriers as the acceptor because of the occurrence of fluorescence resonance energy transfer (FRET), while recovered by the stimuli of basic pH value, which can produce "signal-on" fluorescence detection. Three-dimensional MoS 2 nanoflowers (3D-MoS 2 NFs) were employed in immobilizing CUR to constitute a nanoprobe for the determination of cTnI by virtue of good biocompatibility, high absorption capacity, and fluorescence quench efficiency toward CUR. The proposed DDS-inspired ELISA offered dual-modal colorimetric and fluorescent detection of cTnI, thereby meeting the reliable and precise analysis requirements. We believe that the developed dual-readout ELISA will create a new avenue and bring innovative inspirations for biological detections.

  10. Wideband Single Crystal Transducer for Bone Characterization, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — TRS proposes to develop a simple-to-use, launch capable, ultrasound transducer that is capable of producing the necessary bandwidth to accurately determine in vivo...

  11. Phage Pl mutants with altered transducing abilities for Escherichia coli

    International Nuclear Information System (INIS)

    Wall, J.D.; Harriman, P.D.

    1974-01-01

    A search was made for mutants of the coliphage P1 with altered transducing frequencies. A method was developed for the rapid assay of transducing frequencies in single plaques using prophage lambda as the transduced bacterial marker. This procedure selects for mutants altered in their ability to package host DNA. Mutants with 5 to 10 times higher or 10 to 20 times lower frequencies than those of wild-type P1 were found. Not only are the markers used for the detection of the mutants affected, but all other markers are similarly affected (not always to the same extent). One of the high transducing frequency mutants is a suppressible amber, indicating that loss of a function increases P1's ability to package host DNA preferentially. (U.S.)

  12. Thermal properties photonic crystal fiber transducers with ferromagnetic nanoparticles

    Science.gov (United States)

    Przybysz, N.; Marć, P.; Kisielewska, A.; Jaroszewicz, L. R.

    2015-12-01

    The main aim of the research is to design new types of fiber optic transducers based on filled photonic crystal fibers for sensor applications. In our research we propose to use as a filling material nanoparticles' ferrofluids (Fe3O4 NPs). Optical properties of such transducers are studied by measurements of spectral characteristics' changes when transducers are exposed to temperature and magnetic field changes. From synthesized ferrofluid several mixtures with different NPs' concentrations were prepared. Partially filled commercially available photonic crystal fiber LMA 10 (NKT Photonics) was used to design PCF transducers. Their thermo-optic properties were tested in a temperature chamber. Taking into account magnetic properties of synthetized NPs the patch cords based on a partially filled PM 1550 PCF were measured.

  13. Failure Analysis of High-Power Piezoelectric Transducers

    National Research Council Canada - National Science Library

    Gabrielson, T. B

    2005-01-01

    ... and stress in a piezoelectric material. For a transducer operated near resonance, there will be "hot spots" or regions of locally intense stress and electric field that precipitate premature failure...

  14. Piezoelectric textured ceramics: Effective properties and application to ultrasonic transducers.

    Science.gov (United States)

    Levassort, Franck; Pham Thi, Mai; Hemery, Henry; Marechal, Pierre; Tran-Huu-Hue, Louis-Pascal; Lethiecq, Marc

    2006-12-22

    Piezoelectric textured ceramics obtained by homo-template grain growth (HTGG) were recently demonstrated. A simple model with several assumptions has been used to calculate effective parameters of these new materials. Different connectivities have been simulated to show that spatial arrangements between the considered phases have little influence on the effective parameters, even through the 3-0 connectivity delivers the highest electromechanical thickness factor. A transducer based on a textured ceramic sample has been fabricated and characterised to show the efficiency of these piezoelectric materials. Finally, in a single element transducer configuration, simulation shows an improvement of 2 dB sensitivity for a transducer made with textured ceramic in comparison with a similar transducer design based on standard soft PZT (at equivalent bandwidths).

  15. Detection of plane, poorly oriented wide flaws using focused transducers

    International Nuclear Information System (INIS)

    Vadder, D. de; Azou, P.; Bastien, P.; Saglio, R.

    1976-01-01

    The detection of plane, poorly oriented, wide flaws by ultrasonic non destructive testing is distinctly improved when using focused transducers. An increased echo can be obtained crossing the defect limit [fr

  16. Piezoelectric transducer vibrations in a one-dimensional approximation

    CERN Document Server

    Hilke, H J

    1973-01-01

    The theory of piezoelectric transducer vibrations, which may be treated as one-dimensional, is developed in detail for thin discs vibrating in a pure thickness extensional mode. An effort has been made to obtain relations of general validity, which include losses, and which are in a simple explicit form convenient for practical calculations. The behaviour of transducers is discussed with special attention to their characteristics at the two fundamental frequencies, the so-called parallel and series resonances. Several peculiarities occur when transducers are coupled to media with considerably different acoustic impedances. These peculiarities are discussed and illustrated by numerical results for quartz and PZT 4 piezoelectric discs radiating into water, air and liquid hydrogen. The application of the theory to different types of vibrations is briefly illustrated for thin bars vibrating longitudinally. Short discussions are included on compound transducer systems, and on the properties of thin discs as receiv...

  17. Active Metamaterial Based Ultrasonic Guided Wave Transducer System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — An active and tunable metamaterial phased array transducer for guided wave mode selection with high intensity per driving channel and with dramatically lower modal...

  18. Integration of Capacitive Micromachined Ultrasound Transducers to Microfluidic Devices

    KAUST Repository

    Viržonis, Darius; Kodzius, Rimantas; Vanagas, Galius

    2013-01-01

    The design and manufacturing flexibility of capacitive micromachined ultrasound transducers (CMUT) makes them attractive option for integration with microfluidic devices both for sensing and fluid manipulation. CMUT concept is introduced here

  19. Integration of Capacitive Micromachined Ultrasound Transducers to Microfluidic Devices

    KAUST Repository

    Viržonis, Darius

    2013-10-22

    The design and manufacturing flexibility of capacitive micromachined ultrasound transducers (CMUT) makes them attractive option for integration with microfluidic devices both for sensing and fluid manipulation. CMUT concept is introduced here by presentin

  20. Performance Evaluation of Pressure Transducers for Water Impacts

    Science.gov (United States)

    Vassilakos, Gregory J.; Stegall, David E.; Treadway, Sean

    2012-01-01

    The Orion Multi-Purpose Crew Vehicle is being designed for water landings. In order to benchmark the ability of engineering tools to predict water landing loads, test programs are underway for scale model and full-scale water impacts. These test programs are predicated on the reliable measurement of impact pressure histories. Tests have been performed with a variety of pressure transducers from various manufacturers. Both piezoelectric and piezoresistive devices have been tested. Effects such as thermal shock, pinching of the transducer head, and flushness of the transducer mounting have been studied. Data acquisition issues such as sampling rate and anti-aliasing filtering also have been studied. The response of pressure transducers have been compared side-by-side on an impulse test rig and on a 20-inch diameter hemisphere dropped into a pool of water. The results have identified a range of viable configurations for pressure measurement dependent on the objectives of the test program.

  1. Finite-State Complexity and the Size of Transducers

    Directory of Open Access Journals (Sweden)

    Cristian Calude

    2010-08-01

    Full Text Available Finite-state complexity is a variant of algorithmic information theory obtained by replacing Turing machines with finite transducers. We consider the state-size of transducers needed for minimal descriptions of arbitrary strings and, as our main result, we show that the state-size hierarchy with respect to a standard encoding is infinite. We consider also hierarchies yielded by more general computable encodings.

  2. Test and evaluation of radioactively contaminated transducers and transmitters

    International Nuclear Information System (INIS)

    Strahm, R.C.

    1983-01-01

    People in the nuclear industries face some unique problems when handling, testing, or examining transducers and transmitters that have been radioactively contaminated. Although many people and organizations, including EG and G Idaho, have performed such work for many years, there are no set, structured approaches or procedures. This paper discusses a disciplined laboratory approach to contaminated transducer testing and evaluation, utilizing equipment and facilities developed specifically for this type of work

  3. A theoretical study of cylindrical ultrasound transducers for intracavitary hyperthermia

    International Nuclear Information System (INIS)

    Lin, W.-L.; Fan, W.-C.; Yen, J.-Y.; Chen, Y.-Y.; Shieh, M.-J.

    2000-01-01

    Purpose: The purpose of this paper was to examine the heating patterns and penetration depth when a cylindrical ultrasound transducer is employed for intracavitary hyperthermia treatments. Methods and Materials: The present study employs a simulation program based on a simplified power deposition model for infinitely long cylindrical ultrasound transducers. The ultrasound power in the tissue is assumed to be exponentially attenuated according to the penetration depth of the ultrasound beam, and a uniform attenuation for the entire treatment region is also assumed. The distribution of specific absorption rate (SAR) ratio (the ratio of SAR for a point within the tissue to that for a specific point on the cavity surface) is used to determine the heating pattern for a set of given parameters. The parameters considered are the ultrasound attenuation in the tissue, the cavity size, and the transducer eccentricity. Results: Simulation results show that the ultrasound attenuation in the tissue, the cavity size, and the transducer eccentricity are the most influential parameters for the distribution of SAR ratio. A low frequency transducer located in a large cavity can produce a much better penetration. The cavity size is the major parameter affecting the penetration depth for a small cavity size, such as interstitial hyperthermia. The heating pattern can also be dramatically changed by the transducer eccentricity and radiating sector. In addition, for a finite length of cylindrical transducer, lower SAR ratio appears in the regions near the applicator's edges. Conclusion: The distribution of SAR ratio indicates the relationship between the treatable region and the parameters if an appropriate threshold of SAR ratio is taken. The findings of the present study comprehend whether or not a tumor is treatable, as well as select the optimal driving frequency, the appropriate cavity size, and the eccentricity of a cylindrical transducer for a specific treatment

  4. Design of a Smart Ultrasonic Transducer for Interconnecting Machine Applications

    Directory of Open Access Journals (Sweden)

    Chang Xu

    2009-06-01

    Full Text Available A high-frequency ultrasonic transducer for copper or gold wire bonding has been designed, analyzed, prototyped and tested. Modeling techniques were used in the design phase and a practical design procedure was established and used. The transducer was decomposed into its elementary components. For each component, an initial design was obtained with simulations using a finite elements model (FEM. Simulated ultrasonic modules were built and characterized experimentally through the Laser Doppler Vibrometer (LDV and electrical resonance spectra. Compared with experimental data, the FEM could be iteratively adjusted and updated. Having achieved a remarkably highly-predictive FEM of the whole transducer, the design parameters could be tuned for the desired applications, then the transducer is fixed on the wire bonder with a complete holder clamping was calculated by the FEM. The approach to mount ultrasonic transducers on wire bonding machines also is of major importance for wire bonding in modern electronic packaging. The presented method can lead to obtaining a nearly complete decoupling clamper design of the transducer to the wire bonder.

  5. DESIGN AND IMPLEMENTATION OF POTENTIOMETER-BASED NONLINEAR TRANSDUCER EMULATOR

    Directory of Open Access Journals (Sweden)

    Sheroz Khan

    2011-05-01

    Full Text Available This work attempts to design and implement in hardware a transducer with a nonlinear response using potentiometer. Potentiometer is regarded as a linear transducer, while a the response of a nonlinear transducer can be treated as a concatenation of linear segments made out of the response curve of an actual nonlinear transducer at the points of inflections being exhibited by the nonlinear curve. Each straight line segment is characterized by its slope and a constant, called the y-intercept, which is ultimately realized by a corresponding electronic circuit. The complete circuit diagram is made of three stages: (i the input stage for range selection, (ii a digital logic to make appropriate selection, (iii a conditioning circuit for realizing a given straight-line segment identified by its relevant slope and reference voltage. The simulation of the circuit is carried using MULTISIM, and the designed circuit is afterward tested to verify that variations of the input voltage give us an output voltage very close to the response pattern envisaged in the analytical stage of the design. The utility of this work lies in its applications in emulating purpose built transducers that could be used to nicely emulate a transducer in a real world system that is to be controlled by a programmable digital system.

  6. Experimental Evaluation of Three Designs of Electrodynamic Flexural Transducers

    Directory of Open Access Journals (Sweden)

    Tobias J. R. Eriksson

    2016-08-01

    Full Text Available Three designs for electrodynamic flexural transducers (EDFT for air-coupled ultrasonics are presented and compared. An all-metal housing was used for robustness, which makes the designs more suitable for industrial applications. The housing is designed such that there is a thin metal plate at the front, with a fundamental flexural vibration mode at ∼50 kHz. By using a flexural resonance mode, good coupling to the load medium was achieved without the use of matching layers. The front radiating plate is actuated electrodynamically by a spiral coil inside the transducer, which produces an induced magnetic field when an AC current is applied to it. The transducers operate without the use of piezoelectric materials, which can simplify manufacturing and prolong the lifetime of the transducers, as well as open up possibilities for high-temperature applications. The results show that different designs perform best for the generation and reception of ultrasound. All three designs produced large acoustic pressure outputs, with a recorded sound pressure level (SPL above 120 dB at a 40 cm distance from the highest output transducer. The sensitivity of the transducers was low, however, with single shot signal-to-noise ratio ( SNR ≃ 15 dB in transmit–receive mode, with transmitter and receiver 40 cm apart.

  7. Damage detection in concrete structures with smart piezoceramic transducers

    Science.gov (United States)

    Naidu, Akshay S. K.; Bhalla, Suresh

    2003-10-01

    Detection of damages and progressive deterioration in structures is a critical issue. Visual inspections are tedious and unreliable. Incipient damages are often not discernible by low frequency dynamic response and other NDE techniques. Smart piezoelectric ceramic (PZT) transducers are emerging as an effective alternative in health monitoring of structures. The electro-mechanical impedance method employs the self-actuating and sensing characteristics of the PZT, without having to use actuators and sensors separately. When excited by an ac source, the PZT transducers bonded to the host structure activates the higher modes of vibration locally. Changes in the admittance response of the transducer serves as an indicator of damage around the transducer. In this paper, the effectiveness of PZT transducers for characterizing damages in concrete, in terms of the damage extent and location, is experimentally examined. The root mean square deviation (RMSD) index, adopted to quantify the changes in the admittance signatures, correlates with the damage extent. The damages on the surface that is not mounted by the PZT are also discernible. An array of transducers proves effective in detecting the damaged zone. The progressive incipient crack can be detected much before it actually becomes visible to the naked eye.

  8. Home Automation System Based on Intelligent Transducer Enablers

    Science.gov (United States)

    Suárez-Albela, Manuel; Fraga-Lamas, Paula; Fernández-Caramés, Tiago M.; Dapena, Adriana; González-López, Miguel

    2016-01-01

    This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers), which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet. PMID:27690031

  9. Home Automation System Based on Intelligent Transducer Enablers.

    Science.gov (United States)

    Suárez-Albela, Manuel; Fraga-Lamas, Paula; Fernández-Caramés, Tiago M; Dapena, Adriana; González-López, Miguel

    2016-09-28

    This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers), which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet.

  10. Home Automation System Based on Intelligent Transducer Enablers

    Directory of Open Access Journals (Sweden)

    Manuel Suárez-Albela

    2016-09-01

    Full Text Available This paper presents a novel home automation system named HASITE (Home Automation System based on Intelligent Transducer Enablers, which has been specifically designed to identify and configure transducers easily and quickly. These features are especially useful in situations where many transducers are deployed, since their setup becomes a cumbersome task that consumes a significant amount of time and human resources. HASITE simplifies the deployment of a home automation system by using wireless networks and both self-configuration and self-registration protocols. Thanks to the application of these three elements, HASITE is able to add new transducers by just powering them up. According to the tests performed in different realistic scenarios, a transducer is ready to be used in less than 13 s. Moreover, all HASITE functionalities can be accessed through an API, which also allows for the integration of third-party systems. As an example, an Android application based on the API is presented. Remote users can use it to interact with transducers by just using a regular smartphone or a tablet.

  11. Software for Correcting the Dynamic Error of Force Transducers

    Directory of Open Access Journals (Sweden)

    Naoki Miyashita

    2014-07-01

    Full Text Available Software which corrects the dynamic error of force transducers in impact force measurements using their own output signal has been developed. The software corrects the output waveform of the transducers using the output waveform itself, estimates its uncertainty and displays the results. In the experiment, the dynamic error of three transducers of the same model are evaluated using the Levitation Mass Method (LMM, in which the impact forces applied to the transducers are accurately determined as the inertial force of the moving part of the aerostatic linear bearing. The parameters for correcting the dynamic error are determined from the results of one set of impact measurements of one transducer. Then, the validity of the obtained parameters is evaluated using the results of the other sets of measurements of all the three transducers. The uncertainties in the uncorrected force and those in the corrected force are also estimated. If manufacturers determine the correction parameters for each model using the proposed method, and provide the software with the parameters corresponding to each model, then users can obtain the waveform corrected against dynamic error and its uncertainty. The present status and the future prospects of the developed software are discussed in this paper.

  12. Receive-Noise Analysis of Capacitive Micromachined Ultrasonic Transducers.

    Science.gov (United States)

    Bozkurt, Ayhan; Yaralioglu, G Goksenin

    2016-11-01

    This paper presents an analysis of thermal (Johnson) noise received from the radiation medium by otherwise noiseless capacitive micromachined ultrasonic transducer (CMUT) membranes operating in their fundamental resonance mode. Determination of thermal noise received by multiple numbers of transducers or a transducer array requires the assessment of cross-coupling through the radiation medium, as well as the self-radiation impedance of the individual transducer. We show that the total thermal noise received by the cells of a CMUT has insignificant correlation, and is independent of the radiation impedance, but is only determined by the mass of each membrane and the electromechanical transformer ratio. The proof is based on the analytical derivations for a simple transducer with two cells, and extended to transducers with numerous cells using circuit simulators. We used a first-order model, which incorporates the fundamental resonance of the CMUT. Noise power is calculated by integrating over the entire spectrum; hence, the presented figures are an upper bound for the noise. The presented analyses are valid for a transimpedance amplifier in the receive path. We use the analysis results to calculate the minimum detectable pressure of a CMUT. We also provide an analysis based on the experimental data to show that output noise power is limited by and comparable to the theoretical upper limit.

  13. High Frequency Longitudinal Damped Vibrations of a Cylindrical Ultrasonic Transducer

    Directory of Open Access Journals (Sweden)

    Mihai Valentin Predoi

    2014-01-01

    Full Text Available Ultrasonic piezoelectric transducers used in classical nondestructive testing are producing in general longitudinal vibrations in the MHz range. A simple mechanical model of these transducers would be very useful for wave propagation numerical simulations, avoiding the existing complicated models in which the real components of the transducer are modeled by finite elements. The classical model for longitudinal vibrations is not adequate because the generated longitudinal wave is not dispersive, the velocity being the same at any frequency. We have adopted the Rayleigh-Bishop model, which avoids these limitations, even if it is not converging to the first but to the second exact longitudinal mode in an elastic rod, as obtained from the complicated Pochhammer-Chree equations. Since real transducers have significant vibrations damping, we have introduced a damping term in the Rayleigh-Bishop model, increasing the imaginary part and keeping almost identical real part of the wavenumber. Common transducers produce amplitude modulated signals, completely attenuated after several periods. This can be modeled by two close frequencies, producing a “beat” phenomenon, superposed on the high damping. For this reason, we introduce a two-rod Rayleigh-Bishop model with damping. Agreement with measured normal velocity on the transducer free surface is encouraging for continuation of the research.

  14. DGAT enzymes and triacylglycerol biosynthesis

    OpenAIRE

    Yen, Chi-Liang Eric; Stone, Scot J.; Koliwad, Suneil; Harris, Charles; Farese, Robert V.

    2008-01-01

    Triacylglycerols (triglycerides) (TGs) are the major storage molecules of metabolic energy and FAs in most living organisms. Excessive accumulation of TGs, however, is associated with human diseases, such as obesity, diabetes mellitus, and steatohepatitis. The final and the only committed step in the biosynthesis of TGs is catalyzed by acyl-CoA:diacylglycerol acyltransferase (DGAT) enzymes. The genes encoding two DGAT enzymes, DGAT1 and DGAT2, were identified in the past decade, ...

  15. Immersion apparatus and process for an ultrasonic transducer in a liquid metal

    International Nuclear Information System (INIS)

    Le Baud, P.

    1987-01-01

    The ultrasonic transducer is introduced in a casing. The coupling zone of the transducer is covered by a layer of liquid metal. This layer is solidified and then the transducer with his coating layer is introduced in the liquid metal under an inert atmosphere. The device for immersing the transducer is claimed [fr

  16. Numerical optimization approach for resonant electromagnetic vibration transducer designed for random vibration

    International Nuclear Information System (INIS)

    Spreemann, Dirk; Hoffmann, Daniel; Folkmer, Bernd; Manoli, Yiannos

    2008-01-01

    This paper presents a design and optimization strategy for resonant electromagnetic vibration energy harvesting devices. An analytic expression for the magnetic field of cylindrical permanent magnets is used to build up an electromagnetic subsystem model. This subsystem is used to find the optimal resting position of the oscillating mass and to optimize the geometrical parameters (shape and size) of the magnet and coil. The objective function to be investigated is thereby the maximum voltage output of the transducer. An additional mechanical subsystem model based on well-known equations describing the dynamics of spring–mass–damper systems is established to simulate both nonlinear spring characteristics and the effect of internal limit stops. The mechanical subsystem enables the identification of optimal spring characteristics for realistic operation conditions such as stochastic vibrations. With the overall transducer model, a combination of both subsystems connected to a simple electrical circuit, a virtual operation of the optimized vibration transducer excited by a measured random acceleration profile can be performed. It is shown that the optimization approach results in an appreciable increase of the converter performance

  17. Enzyme detection by microfluidics

    DEFF Research Database (Denmark)

    2013-01-01

    Microfluidic-implemented methods of detecting an enzyme, in particular a DNA-modifying enzyme, are provided, as well as methods for detecting a cell, or a microorganism expressing said enzyme. The enzyme is detected by providing a nucleic acid substrate, which is specifically targeted...... by that enzyme...

  18. Design of a saturated analogue and digital current transducer

    International Nuclear Information System (INIS)

    Pross, Alexander

    2002-01-01

    This project describes the development of a new analogue and digital current transducer, providing a range of new theoretical design methods for these novel devices. The main control feature is the limit cycling operation, and the novel use of the embedded sigma-delta modulator sensor structure to derive a low component count digital sensor. The research programme was initiated into the design, development and evaluation of a novel non-Hall sensing analogue and digital current transducer. These transducers are used for measurement of high currents in power systems applications. The investigation is concerned with a new design which uses a magnetic ferrite core without an air gap for current measurement. The motivation for this work was to design a new control circuit which provides a low component count, and utilises the non-linear properties of the magnetic ferrite core to transmit direct current. The use of a limit cycle control circuit was believed to be particularly suitable for the analogue and digital transducers, for two main reasons: the low component count, and the output signal is directly digital. In line with the motivations outlined above, the outcome of the research has witnessed the design, development and evaluation of a practically realisable analogue and digital current transducer. The design procedure, which is documented in this thesis, is considered to be a major contribution to the field of transducers design and development using a control systems approach. Mathematical models for both analogue and digital transducers were developed and the resulting model based predictions were found to be in good agreement with measured results. Simplification of the new model sensing device was achieved by approximating the non-linear ferrite core using FFT analysis. This is also considered to be a significant contribution. The development analogue and digital current censors employed a sampled data control systems design and utilised limit cycling

  19. Multiple single-element transducer photoacoustic computed tomography system

    Science.gov (United States)

    Kalva, Sandeep Kumar; Hui, Zhe Zhi; Pramanik, Manojit

    2018-02-01

    Light absorption by the chromophores (hemoglobin, melanin, water etc.) present in any biological tissue results in local temperature rise. This rise in temperature results in generation of pressure waves due to the thermoelastic expansion of the tissue. In a circular scanning photoacoustic computed tomography (PACT) system, these pressure waves can be detected using a single-element ultrasound transducer (SUST) (while rotating in full 360° around the sample) or using a circular array transducer. SUST takes several minutes to acquire the PA data around the sample whereas the circular array transducer takes only a fraction of seconds. Hence, for real time imaging circular array transducers are preferred. However, these circular array transducers are custom made, expensive and not easily available in the market whereas SUSTs are cheap and readily available in the market. Using SUST for PACT systems is still cost effective. In order to reduce the scanning time to few seconds instead of using single SUST (rotating 360° ), multiple SUSTs can be used at the same time to acquire the PA data. This will reduce the scanning time by two-fold in case of two SUSTs (rotating 180° ) or by four-fold and eight-fold in case of four SUSTs (rotating 90° ) and eight SUSTs (rotating 45° ) respectively. Here we show that with multiple SUSTs, similar PA images (numerical and experimental phantom data) can be obtained as that of PA images obtained using single SUST.

  20. A piezoelectric transducer for measurement of dynamic strain in pipes

    Energy Technology Data Exchange (ETDEWEB)

    Lannes, Daniel P.; Gama, Antonio L. [Universidade Federal Fluminense (UFF), Niteroi, RJ (Brazil). Dept. de Engenharia Mecanica

    2009-07-01

    This work presents a new strain transducer developed mainly for the inspection and evaluation of piping systems with excessive vibration. Vibration is one of the most common causes of piping failures. These failures could be avoided if the vibration problems were identified and quickly evaluated. Procedures for evaluation of piping vibration are usually based on pipe velocity or displacement. Although simple and fast, these procedures do not provide precise information on the risk of piping fatigue failure. Through the measurement of pipe dynamic strains the risk of failure due to vibration can be determined more accurately. The measurement of strain is usually performed using the conventional strain gauge method. Although efficient and accurate, the implementation of the conventional strain gauge technique may become a difficult task in certain industrial scenarios. Motivated by the need of a simple and rapid method for pipe dynamic strain measurement, a piezoelectric dynamic strain transducer was developed. This work presents a description of the piezoelectric strain transducer and the preliminary results of pipe strain measurements. The transducer can be applied directly to the pipe through magnetic bases allowing for the quick measurement of the dynamic strains in many points of the pipe. The transducer signal can be read with the same commercial data collectors used for accelerometers. (author)

  1. Transducer selection and application in magnetoacoustic tomography with magnetic induction

    International Nuclear Information System (INIS)

    Zhou, Yuqi; Wang, Jiawei; Ma, Qingyu; Sun, Xiaodong; Zhang, Dong

    2016-01-01

    As an acoustic receiver, transducer plays a vital role in signal acquisition and image reconstruction for magnetoacoustic tomography with magnetic induction (MAT-MI). In order to optimize signal acquisition, the expressions of acoustic pressure detection and waveform collection are theoretically studied based on the radiation theory of acoustic dipole and the reception pattern of transducer. Pressure distributions are simulated for a cylindrical phantom model using a planar piston transducer with different radii and bandwidths. The proposed theory is also verified by the experimental measurements of acoustic waveform detection for an aluminum foil cylinder. It is proved that acoustic pressure with sharp and clear boundary peaks can be detected by the large-radius transducer with wide bandwidth, reflecting the differential of the induced Lorentz force accurately, which is helpful for precise conductivity reconstruction. To detect acoustic pressure with acceptable pressure amplitude, peak pressure ratio, amplitude ratio, and improved signal to noise ratio, the scanning radius of 5–10 times the radius of the object should be selected to improve the accuracy of image reconstruction. This study provides a theoretical and experimental basis for transducer selection and application in MAT-MI to obtain reconstructed images with improved resolution and definition.

  2. Transducer selection and application in magnetoacoustic tomography with magnetic induction

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Yuqi; Wang, Jiawei; Ma, Qingyu, E-mail: maqingyu@njnu.edu.cn [Key Laboratory of Optoelectronics of Jiangsu Province, School of Physics and Technology, Nanjing Normal University, Nanjing 210023 (China); Sun, Xiaodong [China Key System & Integrated Circuit Co., Ltd., Wuxi 214072 (China); Zhang, Dong [Laboratory of Modern Acoustics of MOE, Institute of Acoustics, Nanjing University, Nanjing 210093 (China)

    2016-03-07

    As an acoustic receiver, transducer plays a vital role in signal acquisition and image reconstruction for magnetoacoustic tomography with magnetic induction (MAT-MI). In order to optimize signal acquisition, the expressions of acoustic pressure detection and waveform collection are theoretically studied based on the radiation theory of acoustic dipole and the reception pattern of transducer. Pressure distributions are simulated for a cylindrical phantom model using a planar piston transducer with different radii and bandwidths. The proposed theory is also verified by the experimental measurements of acoustic waveform detection for an aluminum foil cylinder. It is proved that acoustic pressure with sharp and clear boundary peaks can be detected by the large-radius transducer with wide bandwidth, reflecting the differential of the induced Lorentz force accurately, which is helpful for precise conductivity reconstruction. To detect acoustic pressure with acceptable pressure amplitude, peak pressure ratio, amplitude ratio, and improved signal to noise ratio, the scanning radius of 5–10 times the radius of the object should be selected to improve the accuracy of image reconstruction. This study provides a theoretical and experimental basis for transducer selection and application in MAT-MI to obtain reconstructed images with improved resolution and definition.

  3. Piezoelectric Polymer Ultrasound Transducers and Its Biomedical Applications

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Kang Lyeol; Cao, Yanggang [Department of Physics, Pukyong National University, Busan (Korea, Republic of)

    2012-10-15

    PVDF(poly vinylidene fluoride) and P(VDF-TrFE)(poly vinylidene fluoride-tetrafluoroethylene) are the typical piezoelectric polymers with unique properties. Even they are inferior to conventional piezoelectric ceramics PZT in electromechanical conversion efficiency and interior loss, though they are superior in receiving sensitivity and frequency bandwidth. Their acoustic impedances are relatively close to water or biological tissue and it is easier to make thin film than other piezoelectric materials. Furthermore, the film is so flexible that it is easy to attach on a complex surface. Those properties are suitable for the ultrasound transducers which are useful for medical and biological application, so that various types of polymer transducers have been developed. In this paper, several important considerations for design and fabrication of piezoelectric polymer transducers were described and their effect on the transducer performance were demonstrated through the KLM model analysis. Then, it was briefly reviewed about the structures of the polymer transducers developed for obtaining images as well as the characteristics of the images in several important medical and biological application fields.

  4. A new hybrid longitudinal–torsional magnetostrictive ultrasonic transducer

    International Nuclear Information System (INIS)

    Karafi, Mohammad Reza; Hojjat, Yousef; Sassani, Farrokh

    2013-01-01

    In this paper, a novel hybrid longitudinal–torsional magnetostrictive ultrasonic transducer (HL–TMUT) is introduced. The transducer is composed of a magnetostrictive exponential horn and a stainless steel tail mass. In this transducer a spiral magnetic field made up of longitudinal and circumferential magnetic fields is applied to the magnetostrictive horn. As a result, the magnetostrictive horn oscillates simultaneously both longitudinally and torsionally in accordance with the Joule and Wiedemann effects. The magnetostrictive exponential horn is designed in such a manner that it has the same longitudinal and torsional resonant frequency. It is made up of ‘2V Permendur’, which has isotropic magnetic properties. The differential equations of the torsional and longitudinal vibration of the horn are derived, and a HL–TMUT is designed with a resonant frequency of 20 573 Hz. The natural frequency and mode shapes of the transducer are considered theoretically and numerically. The experimental results show that this transducer resonates torsionally and longitudinally with frequencies of 20 610 Hz and 20 830 Hz respectively. The maximum torsional displacement is 1.5 mrad m −1 and the maximum longitudinal displacement is 0.6 μm. These are promising features for industrial applications. (paper)

  5. Design of compact piezoelectric transducers for shock wave applications

    Science.gov (United States)

    Dreyer, Thomas; Liebler, Marko; Riedlinger, Rainer E.; Ginter, Siegfried

    2003-10-01

    The application of focused intense sound pulses to treat several orthopedic diseases has gained in importance during the past years. Self-focusing piezoelectric transducers known from ESWL are not well suited for this purpose due to their size. Therefore compact transducers have to be designed. This implies an increase of the pressure pulse amplitude generated at the radiating surface. A stacked placement of two piezoelectric layers driven by two high-voltage pulses with an adjustable delay accomplishes this. Several designs are presented here representing transducers of different sizes. In principle piezoelectric transducers have the ability to vary the pressure pulse shape to a wider extent than other shock wave sources. Based on FEM simulations of the transducer the influence of some driving parameters, like a variation of the interpulse delay or shape of the driving voltage, on the resulting focal pressure signal is demonstrated. The results show the feasibility to control some parameters of the signal, for example the peak negative pressure amplitude. This possibility could provide new aspects in basic research as well as in clinical applications.

  6. Design of HIFU Transducers for Generating Specified Nonlinear Ultrasound Fields.

    Science.gov (United States)

    Rosnitskiy, Pavel B; Yuldashev, Petr V; Sapozhnikov, Oleg A; Maxwell, Adam D; Kreider, Wayne; Bailey, Michael R; Khokhlova, Vera A

    2017-02-01

    Various clinical applications of high-intensity focused ultrasound have different requirements for the pressure levels and degree of nonlinear waveform distortion at the focus. The goal of this paper is to determine transducer design parameters that produce either a specified shock amplitude in the focal waveform or specified peak pressures while still maintaining quasi-linear conditions at the focus. Multiparametric nonlinear modeling based on the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation with an equivalent source boundary condition was employed. Peak pressures, shock amplitudes at the focus, and corresponding source outputs were determined for different transducer geometries and levels of nonlinear distortion. The results are presented in terms of the parameters of an equivalent single-element spherically shaped transducer. The accuracy of the method and its applicability to cases of strongly focused transducers were validated by comparing the KZK modeling data with measurements and nonlinear full diffraction simulations for a single-element source and arrays with 7 and 256 elements. The results provide look-up data for evaluating nonlinear distortions at the focus of existing therapeutic systems as well as for guiding the design of new transducers that generate specified nonlinear fields.

  7. Elevated Liver Enzymes

    Science.gov (United States)

    Symptoms Elevated liver enzymes By Mayo Clinic Staff Elevated liver enzymes may indicate inflammation or damage to cells in the liver. Inflamed or ... than normal amounts of certain chemicals, including liver enzymes, into the bloodstream, which can result in elevated ...

  8. PIXE analysis of Zn enzymes

    International Nuclear Information System (INIS)

    Solis, C.; Oliver, A.; Andrade, E.; Ruvalcaba-Sil, J.L.; Romero, I.; Celis, H.

    1999-01-01

    Zinc is a necessary component in the action and structural stability of many enzymes. Some of them are well characterized, but in others, Zn stoichiometry and its association is not known. PIXE has been proven to be a suitable technique for analyzing metallic proteins embedded in electrophoresis gels. In this study, PIXE has been used to investigate the Zn content of enzymes that are known to carry Zn atoms. These include the carbonic anhydrase, an enzyme well characterized by other methods and the cytoplasmic pyrophosphatase of Rhodospirillum rubrum that is known to require Zn to be stable but not how many metal ions are involved or how they are bound to the enzyme. Native proteins have been purified by polyacrylamide gel electrophoresis and direct identification and quantification of Zn in the gel bands was performed with an external proton beam of 3.7 MeV energy

  9. The AMPK enzyme-complex: From the regulation of cellular energy homeostasis to a possible new molecular target in the management of chronic inflammatory disorders

    NARCIS (Netherlands)

    Antonioli, Luca; Colucci, Rocchina; Pellegrini, Carolina; Giustarini, Giulio; Sacco, Deborah; Tirotta, Erika; Caputi, Valentina; Marsilio, Ilaria; Giron, Maria Cecilia; Németh, Zoltán H; Blandizzi, Corrado; Fornai, Matteo

    2016-01-01

    Introduction: Adenosine monophosphate-activated protein kinase (AMPK), known as an enzymatic complex that regulates the energetic metabolism, is emerging as a pivotal enzyme and enzymatic pathway involved in the regulation of immune homeostatic networks. It is also involved in the molecular

  10. Gibbs Free Energy of Hydrolytic Water Molecule in Acyl-Enzyme Intermediates of a Serine Protease: A Potential Application for Computer-Aided Discovery of Mechanism-Based Reversible Covalent Inhibitors.

    Science.gov (United States)

    Masuda, Yosuke; Yamaotsu, Noriyuki; Hirono, Shuichi

    2017-01-01

    In order to predict the potencies of mechanism-based reversible covalent inhibitors, the relationships between calculated Gibbs free energy of hydrolytic water molecule in acyl-trypsin intermediates and experimentally measured catalytic rate constants (k cat ) were investigated. After obtaining representative solution structures by molecular dynamics (MD) simulations, hydration thermodynamics analyses using WaterMap™ were conducted. Consequently, we found for the first time that when Gibbs free energy of the hydrolytic water molecule was lower, logarithms of k cat were also lower. The hydrolytic water molecule with favorable Gibbs free energy may hydrolyze acylated serine slowly. Gibbs free energy of hydrolytic water molecule might be a useful descriptor for computer-aided discovery of mechanism-based reversible covalent inhibitors of hydrolytic enzymes.

  11. Electromechanical characteristics of discal piezoelectric transducers with spiral interdigitated electrodes

    International Nuclear Information System (INIS)

    Pan, Chengliang; Xiao, Guangjun; Feng, Zhihua; Liao, Wei-Hsin

    2014-01-01

    In this study, piezoceramic thin disks with spiral interdigitated electrodes on their surfaces are proposed to generate in-plane torsional vibrations. Electromechanical characteristics of the discal piezoelectric transducers are investigated. Working principles of the transducers are explained while their static deformations are formulated. Dynamic models are derived to analyze the in-plane torsional vibrations of the disks together with the radial vibrations. The corresponding electromechanical equivalent circuits are also obtained. With different boundary conditions and structural parameters, frequency responses of their electric admittances are calculated numerically. Resonant frequencies, mode shapes, and electromechanical coupling coefficients of the vibration modes are also extracted. Prototype transducers are fabricated and tested to validate the theoretical results. (paper)

  12. Inspection of complex geometry pieces with an intelligent contact transducer

    International Nuclear Information System (INIS)

    Chatillon, S.; Roy, O.; Mahaut, St.

    2000-01-01

    A new multi-element contact transducer has been developed to improve the inspection of components with complex geometry. The emitting surface is flexible in order to optimize the contact with pieces. An algorithm, based on a simplified geometric model, has been used to determine the delays law which allows to control the focal characteristics of the transmitted field. Acquisition data lead in transmission with an articulated transducer validate the behavior provided by simulation. Thus the optimization of the delays law ensures the transmission of a beam which is homogeneous and controlled during the moving of the transducer. Inspections in echo-pulse mode are implemented on a sample simulating a component controlled on site. Results show that the dynamical adaptation of the delays law to the geometry of the piece leads to very good performances

  13. Actuators, transducers and motors based on giant magnetostrictive materials

    Energy Technology Data Exchange (ETDEWEB)

    Claeyssen, F.; Lhermet, N.; Le Letty, R. [Cedrat Recherche, Meylan (France); Bouchilloux, P. [Magsoft Corporation, 1223 People`s Avenue, New York 12180 (United States)

    1997-08-01

    Rare earth-iron magnetostrictive alloys, especially Terfenol-D, feature ``giant`` magnetostrains: static strains of 1000-2000 ppm and dynamic strains of 3500 ppm are reported. These strains permit building various actuating devices (actuators, transducers, motors) both at macro and micro scale. The object of the paper is to recall adapted design methods, especially finite element methods such as ATILA, and to review these different kinds of devices studied at Cedrat Recherche, providing both up-dated experimental and numerical results. The presented devices will include several large displacement longitudinal and shear actuators biased using permanent magnets and used either as characterisation devices or as electromechanical actuators (for active damping, for sonar transducers..), a 1 kHz 4 kW Tonpilz-type sonar transducer called the tripode, a 2 N m torque rotating multi-mode motor, a torsion based drift free micro actuator and a wireless linear micromotor. (orig.)

  14. Torque magnetometry by use of capacitance type transducer

    International Nuclear Information System (INIS)

    Braught, M.C.; Pechan, M.J.

    1992-01-01

    Interfacial anisotropy in magnetic multilayered samples comprised of nanometer thick magnetic layers alternating with non-magnetic layers is investigated by torque magnetometry in the temperature regime of 4 to 300K. The design, construction and use of a capacitance type transducer wherein the sample is mounted directly on with the plate of the capacitor, will be described. As a result the sample and transducer spatially coexist at the sample temperature in an applied external field, eliminating mechanical coupling from the cryogenic region to a remote room temperature transducer. The capacitor measuring the torque of the sample is paired with a reference capacitor. The difference between torque influenced capacitance and the reference is then determined by a differential transimpedance amplifier. Since both capacitors are physically identical variables such as temperature, vibration, orientation and external devices are minimized. Torques up to 300 dyne-cm can be measured with a sensitivity of 0.010 dyne-cm

  15. A novel serrated columnar phased array ultrasonic transducer

    Science.gov (United States)

    Zou, Cheng; Sun, Zhenguo; Cai, Dong; Song, Hongwei; Chen, Qiang

    2016-02-01

    Traditionally, wedges are required to generate transverse waves in a solid specimen and mechanical rotation device is needed for interrogation of a specimen with a hollow bore, such as high speed railway locomotive axles, turbine rotors, etc. In order to eliminate the mechanical rotation process, a novel array pattern of phased array ultrasonic transducers named as serrated columnar phased array ultrasonic transducer (SCPAUT) is designed. The elementary transducers are planar rectangular, located on the outside surface of a cylinder. This layout is aimed to generate electrically rotating transverse waveforms so as to inspect the longitudinal cracks on the outside surface of a specimen which has a hollow bore at the center, such as the high speed railway locomotive axles. The general geometry of the SCPAUT and the inspection system are illustrated. A FEM model and mockup experiment has been carried out. The experiment results are in good agreement with the FEM simulation results.

  16. INFLUENCE OF PIEZOELECTRIC TRANSDUCER TO GLASS FIBER REINFORCED COMPOSITE STIFFNESS

    Directory of Open Access Journals (Sweden)

    Witold Rządkowski

    2015-08-01

    Full Text Available The main goal was to determine if transducers based on piezoelectric materials are suitable for strain calculations in thin GFRP specimens. Numerous experimental studies, both physical and numerical, performed by the authors, have shown that there is a huge influence of bonded piezoelectric transducer on the overall stiffness of the measured object. The paper presents tensile test performed on strength machine with Digital Image Correlation strain and deflection observations. Test were compared with FEM models for detailed investigation. The main conclusion is piezoelectric transducers has huge influence on local stiffness of measured object. That is critical especially when they are used as strain sensors, when presence of sensor is influencing to measured results.

  17. Investigation of Calibrating Force Transducer Using Sinusoidal Force

    International Nuclear Information System (INIS)

    Zhang Li; Wang Yu; Zhang Lizhe

    2010-01-01

    Sinusoidal force calibration method was studied several years before at Physikalisch-Technische Bundesanstalt (PTB). A similar dynamic force calibration system is developed at Changcheng Institute of Metrology and Measurement (CIMM). It uses electro-dynamic shakers to generate dynamic force in the range from 1 N to 20 kN, and heterodyne laser interferometers are used for acceleration measurement. The force transducer to be calibrated is mounted on the shaker, and a mass block is screwed on the top of force transducer, the sinusoidal forces realized by accelerated load masses are traceable to acceleration and mass according to the force definition. The methods of determining Spatial-dependent acceleration on mass block and measuring the end mass of force transducer in dynamic force calibration are discussed in this paper.

  18. Measurement of two-phase flow momentum with force transducers

    International Nuclear Information System (INIS)

    Hardy, J.E.; Smith, J.E.

    1990-01-01

    Two strain-gage-based drag transducers were developed to measure two-phase flow in simulated pressurized water reactor (PWR) test facilities. One transducer, a drag body (DB), was designed to measure the bidirectional average momentum flux passing through an end box. The second drag sensor, a break through detector (BTD), was designed to sense liquid downflow from the upper plenum to the core region. After prototype sensors passed numerous acceptance tests, transducers were fabricated and installed in two experimental test facilities, one in Japan and one in West Germany. High-quality data were extracted from both the DBs and BTDs for a variety of loss-of-coolant accident (LOCA) scenarios. The information collected from these sensors has added to the understanding of the thermohydraulic phenomena that occur during the refill/reflood stage of a LOCA in a PWR. 9 refs., 15 figs

  19. Transducers for the Brazilian gravitational wave detector 'Mario Schenberg'

    International Nuclear Information System (INIS)

    Frajuca, Carlos; Ribeiro, Kilder L; Andrade, Luiz A; Jr, Walter F Velloso; Melo, Jose L; Aguiar, Odylio D; Magalhaes, Nadja S

    2002-01-01

    'Mario Schenberg' is a spherical resonant-mass gravitational wave (GW) detector that will be part of a GW detection array of three detectors. The other two will be built in Italy and the Netherlands. Their resonant frequencies will be around 3.2 kHz with a bandwidth of about 200 Hz. This range of frequencies is new in a field where the typical frequencies lie below 1 kHz, making the transducer development much more complex. In this paper, the design of the mechanical part of the transducer will be shown, as well as the attachment method to the sphere and the expected sensitivity

  20. A digital transducer and digital microphone using an optical technique

    Science.gov (United States)

    Ghelmansarai, F. A.

    1996-09-01

    A transducer is devised to measure pressure, displacements or angles by optical means. This transducer delivers a digital output without relying on interferometry techniques or analogue-to-digital converters. This device is based on an optical scanner and an optical detector. An inter-digital photoconductive detector (IDPC) is employed that delivers a series of pulses, whose number depends on the scan length. A pre-objective scanning configuration is used that allows for the possibility of a flat image plane. The optical scanner provides scanning of IDPC and the generated scan length is proportional to the measurand.

  1. An overview of the dynamic calibration of piezoelectric pressure transducers

    Science.gov (United States)

    Theodoro, F. R. F.; Reis, M. L. C. C.; d’ Souto, C.

    2018-03-01

    Dynamic calibration is a research area that is still under development and is of great interest to aerospace and automotive industries. This study discusses some concepts regarding dynamic measurements of pressure quantities and presents an overview of dynamic calibration of pressure transducers. Studies conducted by the Institute of Aeronautics and Space focusing on research regarding piezoelectric pressure transducer calibration in shock tube are presented. We employed the Guide to the Expression of Uncertainty and a Monte Carlo Method in the methodology. The results show that both device and methodology employed are adequate to calibrate the piezoelectric sensor.

  2. A process chain for integrating piezoelectric transducers into aluminum die castings to generate smart lightweight structures

    Directory of Open Access Journals (Sweden)

    Stefan Stein

    Full Text Available The application of piezoelectric transducers to structural body parts of machines or vehicles enables the combination of passive mechanical components with sensor and actuator functions in one single structure. According to Herold et al. [1] and Staeves [2] this approach indicates significant potential regarding smart lightweight construction. To obtain the highest yield, the piezoelectric transducers need to be integrated into the flux of forces (load path of load bearing structures. Application in a downstream process reduces yield and process efficiency during manufacturing and operation, due to the necessity of a subsequent process step of sensor/actuator application. The die casting process offers the possibility for integration of piezoelectric transducers into metal structures. Aluminum castings are particularly favorable due to their high quality and feasibility for high unit production at low cost (Brunhuber [3], Nogowizin [4]. Such molded aluminum parts with integrated piezoelectric transducers enable functions like active vibration damping, structural health monitoring or energy harvesting resulting in significant possibilities of weight reduction, which is an increasingly important driving force of automotive and aerospace industry (Klein [5], Siebenpfeiffer [6] due to increasingly stringent environmental protection laws. In the scope of those developments, this paper focuses on the entire process chain enabling the generation of lightweight metal structures with sensor and actuator function, starting from the manufacturing of piezoelectric modules over electrical and mechanical bonding to the integration of such modules into aluminum (Al matrices by die casting. To achieve this challenging goal, piezoceramic sensors/actuator modules, so-called LTCC/PZT modules (LPM were developed, since ceramic based piezoelectric modules are more likely to withstand the thermal stress of about 700 °C introduced by the casting process (Flössel et

  3. A study on the performance of piezoelectric composite materials for designing embedded transducers for concrete assessment

    Science.gov (United States)

    Dumoulin, Cédric; Deraemaeker, Arnaud

    2018-03-01

    Ultrasonic measurements of concrete can provide crucial information about its state of health. The most common practice in the construction industry consists in using external probes which strongly limits the use of the method since large parts of the in-service structures are difficult to access. It is also possible to assess in real time the setting process of the concrete using ultrasonic measurements. In practice, the field measurement of the concrete hardening is limited by the formworks. As an alternative, some research teams have studied the possibility to directly embed the transducers into the concrete structures. The current embedded ultrasonic transducers are of two categories: bulk piezoelectric elements surrounded by several coating and matching layers and composites piezoelectric elements. Both technologies aim at optimizing the wave energy transmitted to the tested medium. The performances of the transducers of the first kind have been studied in a previous study. A fair amount of recent research has been focused on the development of novel cement-based piezoelectric composites. In this study, we first compare the effective properties of such cement-based materials with more widespread composites made with matrices of epoxy resins or polyurethane. The study only concerns the 1-3 fiber arrangement composites. The effective properties are computed using both an analytical mixing rule method and a finite element based homogenization method using representative volume elements (RVEs) which allows for considering more realistic fiber arrangements, leading yet to very similar results. The effective piezoelectric properties of cement-based composites appear to be very low compared to composites made of epoxy or polyurethane. This result is underlined by looking at the acoustic response and the electric input impedance of different piezoelectric disks where we compare performances of such transducers with a low-cost bulk piezoelectric disc element. The first

  4. Purification and characterization of the bifunctional uridylyltransferase and the signal transducing proteins GlnB and GlnK from Herbaspirillum seropedicae.

    Science.gov (United States)

    Bonatto, Ana C; Couto, Gustavo H; Souza, Emanuel M; Araújo, Luiza M; Pedrosa, Fabio O; Noindorf, Lilian; Benelli, Elaine M

    2007-10-01

    GlnD is a bifunctional uridylyltransferase/uridylyl-removing enzyme that has a central role in the general nitrogen regulatory system NTR. In enterobacteria, GlnD uridylylates the PII proteins GlnB and GlnK under low levels of fixed nitrogen or ammonium. Under high ammonium levels, GlnD removes UMP from these proteins (deuridylylation). The PII proteins are signal transduction elements that integrate the signals of nitrogen, carbon and energy, and transduce this information to proteins involved in nitrogen metabolism. In Herbaspirillum seropedicae, an endophytic diazotroph isolated from grasses, several genes coding for proteins involved in nitrogen metabolism have been identified and cloned, including glnB, glnK and glnD. In this work, the GlnB, GlnK and GlnD proteins of H. seropedicae were overexpressed in their native forms, purified and used to reconstitute the uridylylation system in vitro. The results show that H. seropedicae GlnD uridylylates GlnB and GlnK trimers producing the forms PII (UMP)(1), PII (UMP)(2) and PII (UMP)(3), in a reaction that requires 2-oxoglutarate and ATP, and is inhibited by glutamine. The quantification of these PII forms indicates that GlnB was more efficiently uridylylated than GlnK in the system used.

  5. A new class of variable capacitance generators based on the dielectric fluid transducer

    Science.gov (United States)

    Duranti, Mattia; Righi, Michele; Vertechy, Rocco; Fontana, Marco

    2017-11-01

    This paper introduces the novel concept of dielectric fluid transducer (DFT), which is an electrostatic variable capacitance transducer made by compliant electrodes, solid dielectrics and a dielectric fluid with variable volume and/or shape. The DFT can be employed in actuator mode and generator mode. In this work, DFTs are studied as electromechanical generators able to convert oscillating mechanical energy into direct current electricity. Beside illustrating the working principle of dielectric fluid generators (DFGs), we introduce different architectural implementations and provide considerations on limitations and best practices for their design. Additionally, the proposed concept is demonstrated in a preliminary experimental test campaign conducted on a first DFG prototype. During experimental tests a maximum energy per cycle of 4.6 {mJ} and maximum power of 0.575 {mW} has been converted, with a conversion efficiency up to 30%. These figures correspond to converted energy densities of 63.8 {mJ} {{{g}}}-1 with respect to the displaced dielectric fluid and 179.0 {mJ} {{{g}}}-1 with respect to the mass of the solid dielectric. This promising performance can be largely improved through the optimization of device topology and dimensions, as well as by the adoption of more performing conductive and dielectric materials.

  6. Engineering Cellulase Enzymes for Bioenergy

    Science.gov (United States)

    Atreya, Meera Elizabeth

    Sustainable energy sources, such as biofuels, offer increasingly important alternatives to fossil fuels that contribute less to global climate change. The energy contained within cellulosic biofuels derives from sunlight energy stored in the form of carbon-carbon bonds comprising sugars such as glucose. Second-generation biofuels are produced from lignocellulosic biomass feedstocks, including agricultural waste products and non-food crops like Miscanthus, that contain lignin and the polysaccharides hemicellulose and cellulose. Cellulose is the most abundant biological material on Earth; it is a polymer of glucose and a structural component of plant cell walls. Accessing the sugar is challenging, as the crystalline structure of cellulose resists degradation; biochemical and thermochemical means can be used to depolymerize cellulose. Cellulase enzymes catalyze the biochemical depolymerization of cellulose into glucose. Glucose can be used as a carbon source for growth of a biofuel-producing microorganism. When it converts glucose to a hydrocarbon fuel, this microbe completes the biofuels process of transforming sunlight energy into accessible, chemical energy capable of replacing non-renewable transportation fuels. Due to strong intermolecular interactions between polymer chains, cellulose is significantly more challenging to depolymerize than starch, a more accessible polymer of glucose utilized in first-generation biofuels processes (often derived from corn). While most mammals cannot digest cellulose (dietary fiber), certain fungi and bacteria produce cellulase enzymes capable of hydrolyzing it. These organisms secrete a wide variety of glycoside hydrolase and other classes of enzymes that work in concert. Because cellulase enzymes are slow-acting and expensive to produce, my aim has been to improve the properties of these enzymes as a means to make a cellulosic biofuels process possible that is more efficient and, consequently, more economical than current

  7. Protein Kinase C Enzymes in the Hematopoietic and Immune Systems.

    Science.gov (United States)

    Altman, Amnon; Kong, Kok-Fai

    2016-05-20

    The protein kinase C (PKC) family, discovered in the late 1970s, is composed of at least 10 serine/threonine kinases, divided into three groups based on their molecular architecture and cofactor requirements. PKC enzymes have been conserved throughout evolution and are expressed in virtually all cell types; they represent critical signal transducers regulating cell activation, differentiation, proliferation, death, and effector functions. PKC family members play important roles in a diverse array of hematopoietic and immune responses. This review covers the discovery and history of this enzyme family, discusses the roles of PKC enzymes in the development and effector functions of major hematopoietic and immune cell types, and points out gaps in our knowledge, which should ignite interest and further exploration, ultimately leading to better understanding of this enzyme family and, above all, its role in the many facets of the immune system.

  8. Analysis of eigenfrequencies in piezoelectric transducers using the finite element method

    DEFF Research Database (Denmark)

    Jensen, Henrik

    1988-01-01

    transducers, which include the complete set of piezoelectric equations, have been included. They can find eigenfrequencies for undamped transducers and perform forced-response analysis for transducers with internal and radiation damping. The superelement technique is used to model the transducer backing......It is noted that the finite-element method is a valuable supplement to the traditional methods for design of novel transducer types because it can determine the vibrational pattern of piezoelectric transducers and is applicable to any geometry. Computer programs for analysis of axisymmetric...

  9. Determination of the response time of pressure transducers using the direct method

    International Nuclear Information System (INIS)

    Perillo, S.R.P.

    1994-01-01

    The available methods to determine the response time of nuclear safety related pressure transducers are discussed, with emphasis to the direct method. In order to perform the experiments, a Hydraulic Ramp Generator was built. The equipment produces ramp pressure transients simultaneously to a reference transducer and to the transducer under test. The time lag between the output of the two transducers, when they reach a predetermined setpoint, is measured as the time delay of the transducer under test. Some results using the direct method to determine the time delay of pressure transducers (1 E Class Conventional) are presented. (author). 18 refs, 35 figs, 12 tabs

  10. Wall thickness tests by means of rotating electrodynamic transducers

    International Nuclear Information System (INIS)

    Hueschelrath, G.

    1986-01-01

    For about three years, the EROT system has been employed for measuring wall thicknesses on pipes of ferritic steels. The experience gathered and the degree of reliability reached up to now are definitely encouraging, so that an increased use of electrodynamic transducers can be expected for measuring pipes with outside diameters of up to 22 inches. (orig.) [de

  11. A New High-Temperature Ultrasonic Transducer for Continuous Inspection.

    Science.gov (United States)

    Amini, Mohammad Hossein; Sinclair, Anthony N; Coyle, Thomas W

    2016-03-01

    A novel design of piezoelectric ultrasonic transducer is introduced, suitable for operation at temperatures of up to 700 °C-800 °C. Lithium niobate single crystal is chosen as the piezoelectric element primarily due to the high Curie temperature of 1200 °C. A backing element based on a porous ceramic is designed for which the pore volume fraction and average pore diameter in the ceramic matrix can be controlled in the manufacturing process; this enables the acoustic impedance and attenuation to be selected to match their optimal values as predicted by a one-dimensional transducer model of the entire transducer. Porous zirconia is selected as the ceramic matrix material of the backing element to obtain an ultrasonic signal with center frequency of 2.7-3 MHz, and 3-dB bandwidth of 90%-95% at the targeted operating temperature. Acoustic coupling of the piezocrystal to the backing element and matching layer is investigated using commercially available high-temperature adhesives and brazing alloys. The performance of the transducer as a function of temperature is studied. Stable bonding and clear signals were obtained using an aluminum brazing alloy as the bonding agent.

  12. Universal Quantum Transducers Based on Surface Acoustic Waves

    NARCIS (Netherlands)

    Schuetz, M.J.A.; Kessler, E.M.; Giedke, G.; Vandersypen, L.M.K.; Lukin, M.D.; Cirac, J.I.

    2015-01-01

    We propose a universal, on-chip quantum transducer based on surface acoustic waves in piezoactive materials. Because of the intrinsic piezoelectric (and/or magnetostrictive) properties of the material, our approach provides a universal platform capable of coherently linking a broad array of qubits,

  13. Instantaneous input electrical power measurements of HITU transducer

    Energy Technology Data Exchange (ETDEWEB)

    Karaboece, B; Guelmez, Y [Tuebitak Ulusal Metroloji Enstituesue (UME), P.K. 54 41470 Gebze-Kocaeli (Turkey); Rajagapol, S; Shaw, A, E-mail: baki.karaboce@ume.tubitak.gov.t [National Physical Laboratory (NPL), Hampton Road, Teddington TW11 0LW (United Kingdom)

    2011-02-01

    HITU (High Intensity Theraupetic Ultrasound) transducers are widely used in therapeutic ultrasound in medicine. The output ultrasonic power of HITU transducer can be measured in number of methods described in IEC 61161 standard [1]. New IEC standards specifically for measurement of HITU equipment are under development. The ultrasound power radiated from a transducer is dependent on applied input electrical voltage and current and consequently power. But, up to now, no standardised method has been developed and adopted for the input electrical power measurements. Hence, a workpackage was carried out for the establishment of such method in the frequency range of 1 to 3 MHz as a part of EURAMET EMRP Era-net plus 'External Beam Cancer Therapy' project. Several current shunts were developed and evaluated. Current measurements were also realized with Philips current probe and preamplifier at NPL and Agilent current probe at UME. In this paper, a method for the measurement of instantaneous electrical power delivered to a reactive ultrasound transducer in the required frequency range is explored.

  14. Neutron Irradiation Tests of Pressure Transducers in Liquid Helium

    CERN Document Server

    Amand, J F; Casas-Cubillos, J; Thermeau, J P

    1999-01-01

    The superconducting magnets of the future Large Hadron Collider (LHC) at CERN will operate in pressurised superfluid helium (1 bar, 1.9 K). About 500 pressure transducers will be placed in the liquid helium bath for monitoring the filling and the pressure transients after resistive transitions. Their precision must remain better than 100 mbar at pressures below 2 bar and better than 5% for higher pressures (up to 20 bar), with temperatures ranging from 1.8 K to 300 K. All the tested transducers are based on the same principle: the fluid or gas is separated from a sealed reference vacuum by an elastic membrane; its deformation indicates the pressure. The transducers will be exposed to high neutron fluence (2 kGy, 1014 n/cm2 per year) during the 20 years of machine operation. This irradiation may induce changes both on the membranes characteristics (leakage, modification of elasticity) and on gauges which measure their deformations. To investigate these effects and select the transducer to be used in the LHC, a...

  15. Nonlinear Dynamic Modeling of Langevin-Type Piezoelectric Transducers

    Directory of Open Access Journals (Sweden)

    Nicolás Peréz Alvarez

    2015-11-01

    Full Text Available Langevin transducers are employed in several applications, such as power ultrasound systems, naval hydrophones, and high-displacement actuators. Nonlinear effects can influence their performance, especially at high vibration amplitude levels. These nonlinear effects produce variations in the resonant frequency, harmonics of the excitation frequency, in addition to loss of symmetry in the frequency response and “frequency domain hysteresis”. In this context, this paper presents a simplified nonlinear dynamic model of power ultrasound transducers requiring only two parameters for simulating the most relevant nonlinear effects. One parameter reproduces the changes in the resonance frequency and the other introduces the dependence of the frequency response on the history of the system. The piezoelectric constitutive equations are extended by a linear dependence of the elastic constant on the mechanical displacement amplitude. For introducing the frequency hysteresis, the elastic constant is computed by combining the current value of the mechanical amplitude with the previous state amplitude. The model developed in this work is applied for predicting the dynamic responses of a 26 kHz ultrasonic transducer. The comparison of theoretical and experimental responses, obtained at several input voltages around the tuned frequency, shows a good agreement, indicating that the model can accurately describe the transducer nonlinear behavior.

  16. Analysis of a non-contact magnetoelastic torque transducer

    International Nuclear Information System (INIS)

    Andreescu, R.; Spellman, B.; Furlani, E.P.

    2008-01-01

    Results are presented for the performance of a magnetoelastic torque transducer that converts a torque-induced strain in a non-magnetic shaft into changes in a measurable magnetic field. The magnetic field is generated by a thin magnetostrictive layer that is coated onto the circumference of the shaft. The layer is magnetized and has an initial residual strain. The magnetization within the layer rotates in response to changes in the strain which occur when the shaft is torqued. The magnetic field produced by the layer changes with the magnetization and this can be sensed by a magnetometer to monitor the torque on the shaft. In this paper, a phenomenological theory is developed for predicting the performance of the transducer. The theory can be used to predict the magnetic field distribution of the transducer as a function of the physical properties of the magnetic coating, its residual strain, and the applied torque. It enables rapid parametric analysis of transducer performance, which is useful for the development and optimization of novel non-contact torque sensors

  17. Power doppler 'blanching' after the application of transducer pressure

    International Nuclear Information System (INIS)

    Joshua, F.; Edmonds, J.; Lassere, M.; De Carle, R.; Rayment, M.; Bryant, C.; Shnier, R.

    2005-01-01

    The aim of this study was to determine if transducer pressure modifies power Doppler assessments of rheumatoid arthritis synovium at the metacarpophalangeal joints and metatarsophalangeal joints. Five rheumatoid arthritis patients of varying degrees of 'disease activity' and damage were assessed with power Doppler ultrasound scanning of the dominant hand second to fifth metacarpophalangeal joints. Two rheumatoid arthritis patients had their dominant foot first to fifth metatarsophalangeal joints assessed with power Doppler ultrasound. Ultrasonography was performed with a high frequency transducer (14 MHz) with a colour mode frequency of 10 Mhz, and a standard colour box and gain. In the joint that showed the highest power Doppler signal, an image was made. A further image was taken after transducer pressure was applied. In all patients, there was increased flow to at least one joint. After pressure was applied, power Doppler signal intensity markedly reduced in all images and in some there was no recordable power Doppler signal. Increased transducer pressure can result in a marked reduction or obliteration in power Doppler signal. This power Doppler 'blanching' shows the need for further studies to evaluate sources of error and standardization before power Doppler ultrasound becomes a routine measure of 'disease activity' in rheumatoid arthritis. Copyright (2005) Blackwell Science Pty Ltd

  18. Testing of electron beam welding by ultrasonic transducers

    International Nuclear Information System (INIS)

    Touffait, A.-M.; Roule, M.; Destribats, M.-T.

    1978-01-01

    Focalized ultrasonic testing is well adapted to the study of electron beam welding. This type of welding leads to narrow weld beads and to small dimension testing zones. Focalized transducers can be used enabling very small defects to be detected [fr

  19. Instantaneous input electrical power measurements of HITU transducer

    International Nuclear Information System (INIS)

    Karaboece, B; Guelmez, Y; Rajagapol, S; Shaw, A

    2011-01-01

    HITU (High Intensity Theraupetic Ultrasound) transducers are widely used in therapeutic ultrasound in medicine. The output ultrasonic power of HITU transducer can be measured in number of methods described in IEC 61161 standard [1]. New IEC standards specifically for measurement of HITU equipment are under development. The ultrasound power radiated from a transducer is dependent on applied input electrical voltage and current and consequently power. But, up to now, no standardised method has been developed and adopted for the input electrical power measurements. Hence, a workpackage was carried out for the establishment of such method in the frequency range of 1 to 3 MHz as a part of EURAMET EMRP Era-net plus 'External Beam Cancer Therapy' project. Several current shunts were developed and evaluated. Current measurements were also realized with Philips current probe and preamplifier at NPL and Agilent current probe at UME. In this paper, a method for the measurement of instantaneous electrical power delivered to a reactive ultrasound transducer in the required frequency range is explored.

  20. Enhancing endosomal escape of transduced proteins by photochemical internalisation.

    Directory of Open Access Journals (Sweden)

    Kevin Mellert

    Full Text Available Induced internalisation of functional proteins into cultured cells has become an important aspect in a rising number of in vitro and in vivo assays. The endo-lysosomal entrapment of the transduced proteins remains the major problem in all transduction protocols. In this study we compared the efficiency, cytotoxicity and protein targeting of different commercially available transduction reagents by transducing a well-studied fluorescently labelled protein (Atto488-bovine serum albumin into cultured human sarcoma cells. The amount of internalised protein and toxicity differed between the different reagents, but the percentage of transduced cells was consistently high. Furthermore, in all protocols the signals of the transduced Atto488-BSA were predominantly punctual consistent with an endosomal localisation. To overcome the endosomal entrapment, the transduction protocols were combined with a photochemical internalisation (PCI treatment. Using this combination revealed that an endosomal disruption is highly effective in cell penetrating peptide (CPP mediated transduction, whereas lipid-mediated transductions lead to a lower signal spreading throughout the cytosol. No change in the signal distribution could be achieved in treatments using non-lipid polymers as a transduction reagent. Therefore, the combination of protein transduction protocols based on CPPs with the endosomolytic treatment PCI can facilitate protein transduction experiments in vitro.

  1. Enhancing endosomal escape of transduced proteins by photochemical internalisation.

    Science.gov (United States)

    Mellert, Kevin; Lamla, Markus; Scheffzek, Klaus; Wittig, Rainer; Kaufmann, Dieter

    2012-01-01

    Induced internalisation of functional proteins into cultured cells has become an important aspect in a rising number of in vitro and in vivo assays. The endo-lysosomal entrapment of the transduced proteins remains the major problem in all transduction protocols. In this study we compared the efficiency, cytotoxicity and protein targeting of different commercially available transduction reagents by transducing a well-studied fluorescently labelled protein (Atto488-bovine serum albumin) into cultured human sarcoma cells. The amount of internalised protein and toxicity differed between the different reagents, but the percentage of transduced cells was consistently high. Furthermore, in all protocols the signals of the transduced Atto488-BSA were predominantly punctual consistent with an endosomal localisation. To overcome the endosomal entrapment, the transduction protocols were combined with a photochemical internalisation (PCI) treatment. Using this combination revealed that an endosomal disruption is highly effective in cell penetrating peptide (CPP) mediated transduction, whereas lipid-mediated transductions lead to a lower signal spreading throughout the cytosol. No change in the signal distribution could be achieved in treatments using non-lipid polymers as a transduction reagent. Therefore, the combination of protein transduction protocols based on CPPs with the endosomolytic treatment PCI can facilitate protein transduction experiments in vitro.

  2. Electrical capacity and resistance determination of emitting electric transducer

    International Nuclear Information System (INIS)

    Alba Fernandez, J.; Ramis Soriano, J.

    2000-01-01

    In this work we calculate the electrical resistance and capacity of emitting electric transducer, which is mainly formed, in direct relationship with its properties, by a ceramic capacitor. Our aim is to motivate the students with an attractive element in order to carry out traditional measurements of the charge and discharge transients of a capacitor, implementing high resistance setups. (Author) 5 refs

  3. Analysis of the conical piezoelectric acoustic emission transducer

    Czech Academy of Sciences Publication Activity Database

    Červená, Olga; Hora, Petr

    2008-01-01

    Roč. 2, č. 1 (2008), s. 13-24 ISSN 1802-680X R&D Projects: GA ČR GA101/06/1689 Institutional research plan: CEZ:AV0Z20760514 Keywords : acoustic emission * conical transducer * FEM Subject RIV: BI - Acoustics

  4. Multilevel inverter based class D audio amplifier for capacitive transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    The reduced semiconductor voltage stress makes the multilevel inverters especially interesting, when driving capacitive transducers for audio applications. A ± 300 V flying capacitor class D audio amplifier driving a 100 nF load in the midrange region of 0.1-3.5 kHz with Total Harmonic Distortion...

  5. Multilayer piezoelectric transducer models combined with Field II

    DEFF Research Database (Denmark)

    Bæk, David; Willatzen, Morten; Jensen, Jørgen Arendt

    2012-01-01

    One-dimensional and three-dimensional axisymmetric transducer model have been compared to determine their feasibility to predict the volt-to-surface impulse response of a circular Pz27 piezoceramic disc. The ceramic is assumed mounted with silver electrodes, bounded at the outer circular boundary...

  6. Lithium niobate ultrasonic transducer design for Enhanced Oil Recovery.

    Science.gov (United States)

    Wang, Zhenjun; Xu, Yuanming; Gu, Yuting

    2015-11-01

    Due to the strong piezoelectric effect possessed by lithium niobate, a new idea that uses lithium niobate to design high-power ultrasonic transducer for Enhanced Oil Recovery technology is proposed. The purpose of this paper is to lay the foundation for the further research and development of high-power ultrasonic oil production technique. The main contents of this paper are as follows: firstly, structure design technique and application of a new high-power ultrasonic transducer are introduced; secondly, the experiment for reducing the viscosity of super heavy oil by this transducer is done, the optimum ultrasonic parameters for reducing the viscosity of super heavy oil are given. Experimental results show that heavy large molecules in super heavy oil can be cracked into light hydrocarbon substances under strong cavitation effect caused by high-intensity ultrasonic wave. Experiment proves that it is indeed feasible to design high-power ultrasonic transducer for ultrasonic oil production technology using lithium niobate. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Transducer frequency response variations investigated by time reversal calibration

    Czech Academy of Sciences Publication Activity Database

    Kober, Jan; Převorovský, Zdeněk

    2016-01-01

    Roč. 26, č. 2 (2016), A16-A16 ISSN 1213-3825. [Europen Conference on Acoustic Emission Testing /32./. 07.09.2016-09.09.2016, Praha] Institutional support: RVO:61388998 Keywords : calibration * time reversal * transducer * frequency response Subject RIV: BI - Acoustics

  8. Modelling of multilayer piezoelectric transducers for echographic applications Equivalent circuits

    International Nuclear Information System (INIS)

    Ramos, A.; Riera, E.; San Emeterio, J.L.; Sanz, P.T.

    1988-01-01

    In this paper, the main equivalent circuits of pulse-echo, single element, multilayer piezoelectric transducers, are analysed. The analogy of matching layers with lossless transmission lines is described. Finally, using the KLM model, the effects of backing and matching layers on the bandwidth and impulse response is analysed. (Author)

  9. A Novel Rotary Piezoelectric Motor Using First Bending Hybrid Transducers

    Directory of Open Access Journals (Sweden)

    Yingxiang Liu

    2015-08-01

    Full Text Available We report a novel rotary piezoelectric motor using bending transducers in this work. Three transducers are used to drive a disk-shaped rotor together by the elliptical movements of their driving tips; these motions are produced by the hybrid of two first bending vibration modes. The proposed piezoelectric transducer has a simple structure as it only contains an aluminum alloy beam and four pieces of PZT plates. Symmetrical structure is the only necessary condition in the design process as it will ensure the resonance frequencies of the two orthogonal first bending modes are equal. Transducers with first bending resonance frequency of about 53 kHz were fabricated and assembled into a rotary motor. The proposed motor exhibits good performance on speed and torque control. Under a working frequency of 53.2 kHz, the maximum no-load speed and the maximum torque of the prototype are tested to be 53.3 rpm and of 27 mN·m.

  10. Effect of stimuli, transducers and gender on acoustic change complex

    Directory of Open Access Journals (Sweden)

    Hemanth N. Shetty

    2012-08-01

    Full Text Available The objective of this study was to investigate the effect of stimuli, transducers and gender on the latency and amplitude of acoustic change complex (ACC. ACC is a multiple overlapping P1-N1-P2 complex reflecting acoustic changes across the entire stimulus. Fifteen males and 15 females, in the age range of 18 to 25 (mean=21.67 years, having normal hearing participated in the study. The ACC was recorded using the vertical montage. The naturally produced stimuli /sa/ and /si/ were presented through the insert earphone/loud speaker to record the ACC. The ACC obtained from different stimuli presented through different transducers from male/female participants were analyzed using mixed analysis of variance. Dependent t-test and independent t-test were performed when indicated. There was a significant difference in latency of 2N1 at the transition, with latency for /sa/ being earlier; but not at the onset portions of ACC. There was no significant difference in amplitude of ACC between the stimuli. Among the transducers, there was no significant difference in latency and amplitude of ACC, for both /sa/ and /si/ stimuli. Female participants showed earlier latency for 2N1 and larger amplitude of N1 and 2P2 than male participants, which was significant. ACC provides important insight in detecting the subtle spectral changes in each stimulus. Among the transducers, no difference in ACC was noted as the spectra of stimuli delivered were within the frequency response of the transducers. The earlier 2N1 latency and larger N1 and 2P2 amplitudes noticed in female participants could be due to smaller head circumference. The findings of this study will be useful in determining the capacity of the auditory pathway in detecting subtle spectral changes in the stimulus at the level of the auditory cortex.

  11. Development of transducers for integrated garter spring repositioning system

    Energy Technology Data Exchange (ETDEWEB)

    Sharma, B S.V.G.; Shyam, T V; Shrivastava, A K; Rupani, B B; Sinha, R K [Bhabha Atomic Research Centre, Bombay (India). Reactor Engineering Div.

    1994-12-31

    In order to reposition the dislocated garter springs in active channels of 235 MW Pressurised Heavy Water Reactors (PHWRs), a tool named as Integrated Garter Spring Repositioning System (INGRES) has been developed. The tool consists of transducers to detect the concentricity between the Pressure Tube (P/T) and Calandria Tube (C/T) and also to detect garter springs in the channel besides different modules for correcting the eccentricity between P/T and C/T and garter spring repositioning. The transducers used in the system namely Concentricity Detection Probe (CDP) and Garter Spring Detection Probe (GSDP) are based on the eddy current techniques. The CDP makes use of four eddy current bobbin probes separated 90 degrees apart in cross sectional plane of channel assembly. The transducer gives output signal in proportional to the air gap between P/T and C/T in two axes (X and Y) which are designed for the purpose. The output of the unit is obtained on the Cathode Ray Oscilloscope (CRO) screen in the form of illuminated dot. The dot position on the CRO screen gives the information about mismatch in concentricity between P/T and C/T of the channel. The GSDP meant for detecting garter springs in PHWR channel uses two sets of primary and secondary coils connected in differential mode. The output signals from the transducers are processed through a signal processing unit devised for the purpose to obtain output from it as a horizontal beam on the CRO screen. The garter spring presence in the channel is indicated by a change in the voltage level of beam and also by audio-visual indication in the form of buzzer and LED illumination on the processing unit. This paper gives general design and development aspects of the CDP and GSDP transducers of the INGRES tool. (author). 3 figs.

  12. Piezoelectric polydimethylsiloxane films for MEMS transducers

    International Nuclear Information System (INIS)

    Wang, Jhih-Jhe; Hsu, Tsung-Hsing; Yeh, Che-Nan; Tsai, Jui-Wei; Su, Yu-Chuan

    2012-01-01

    We have successfully demonstrated the fabrication of piezoelectric polydimethylsiloxane (PDMS) films utilizing multilayer casting, stacking, surface coating and micro plasma discharge processes. To realize the desired electromechanical sensitivity, cellular PDMS structures with micrometer-sized voids are implanted with bipolar charges on the opposite inner surfaces. The implanted charge pairs function as dipoles, which respond promptly to diverse electromechanical stimulation. In the prototype demonstration, cellular PDMS films with various void geometries are fabricated and internally coated with a thin layer of polytetrafluoroethylene, which can help secure the implanted charges. An electric field up to 35 MV m −1 is applied across the fabricated PDMS films to ionize the air in the voids and to accelerate the resulting bipolar charges to bombard the opposite inner surfaces. The resulting charge-implanted, cellular PDMS films show a low effective elastic modulus (E) of about 500 kPa, and a piezoelectric coefficient (d 33 ) higher than 300 pC N −1 , which is more than ten times higher than those of common piezoelectric polymers (e.g. polyvinylidene fluoride). Furthermore, the piezoelectricity of the PDMS films can be tailored by adjusting the dimensions of the cellular structures. As such, the demonstrated piezoelectric PDMS films could potentially serve as flexible and sensitive electromechanical materials, and fulfill the needs of a variety of sensor and energy harvesting applications. (paper)

  13. Six-Axis Force-Torque Transducer for Mars 2018 Mission, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — A transducer element that is hearty enough for a Mars lander mission needs to be developed so that a six-axis force and torque transducer is possible. The technical...

  14. Enzymes in CO2 Capture

    DEFF Research Database (Denmark)

    Fosbøl, Philip Loldrup; Gladis, Arne; Thomsen, Kaj

    The enzyme Carbonic Anhydrase (CA) can accelerate the absorption rate of CO2 into aqueous solutions by several-fold. It exist in almost all living organisms and catalyses different important processes like CO2 transport, respiration and the acid-base balances. A new technology in the field...... of carbon capture is the application of enzymes for acceleration of typically slow ternary amines or inorganic carbonates. There is a hidden potential to revive currently infeasible amines which have an interesting low energy consumption for regeneration but too slow kinetics for viable CO2 capture. The aim...... of this work is to discuss the measurements of kinetic properties for CA promoted CO2 capture solvent systems. The development of a rate-based model for enzymes will be discussed showing the principles of implementation and the results on using a well-known ternary amine for CO2 capture. Conclusions...

  15. Piezoelectric micromachined ultrasonic transducers for fingerprint sensing

    Science.gov (United States)

    Lu, Yipeng

    Fingerprint identification is the most prevalent biometric technology due to its uniqueness, universality and convenience. Over the past two decades, a variety of physical mechanisms have been exploited to capture an electronic image of a human fingerprint. Among these, capacitive fingerprint sensors are the ones most widely used in consumer electronics because they are fabricated using conventional complementary metal oxide semiconductor (CMOS) integrated circuit technology. However, capacitive fingerprint sensors are extremely sensitive to finger contamination and moisture. This thesis will introduce an ultrasonic fingerprint sensor using a PMUT array, which offers a potential solution to this problem. In addition, it has the potential to increase security, as it allows images to be collected at various depths beneath the epidermis, providing images of the sub-surface dermis layer and blood vessels. Firstly, PMUT sensitivity is maximized by optimizing the layer stack and electrode design, and the coupling coefficient is doubled via series transduction. Moreover, a broadband PMUT with 97% fractional bandwidth is achieved by utilizing a thinner structure excited at two adjacent mechanical vibration modes with overlapping bandwidth. In addition, we proposed waveguide PMUTs, which function to direct acoustic waves, confine acoustic energy, and provide mechanical protection for the PMUT array. Furthermore, PMUT arrays were fabricated with different processes to form the membrane, including front-side etching with a patterned sacrificial layer, front-side etching with additional anchor, cavity SOI wafers and eutectic bonding. Additionally, eutectic bonding allows the PMUT to be integrated with CMOS circuits. PMUTs were characterized in the mechanical, electrical and acoustic domains. Using transmit beamforming, a narrow acoustic beam was achieved, and high-resolution (sub-100 microm) and short-range (~1 mm) pulse-echo ultrasonic imaging was demonstrated using a steel

  16. Eddy Current Transducer Dedicated for Sigma Phase Evaluation in Duplex Stainless Steel

    Directory of Open Access Journals (Sweden)

    Grzegorz Psuj

    2012-01-01

    Full Text Available The paper describes a new transducer dedicated for evaluation of a duplex stainless steel (DSS. Different phases which exist in DSS have influence on mechanical as well as on electrical properties. Therefore, an eddy current transducer was utilized. In order to achieve high sensitivity, a differential type of the transducer was selected. The performance of the transducer was verified by utilizing the samples which had a different amount of sigma phase.

  17. Techno-economic analysis of the deacetylation and disk refining process: characterizing the effect of refining energy and enzyme usage on minimum sugar selling price and minimum ethanol selling price.

    Science.gov (United States)

    Chen, Xiaowen; Shekiro, Joseph; Pschorn, Thomas; Sabourin, Marc; Tucker, Melvin P; Tao, Ling

    2015-01-01

    A novel, highly efficient deacetylation and disk refining (DDR) process to liberate fermentable sugars from biomass was recently developed at the National Renewable Energy Laboratory (NREL). The DDR process consists of a mild, dilute alkaline deacetylation step followed by low-energy-consumption disk refining. The DDR corn stover substrates achieved high process sugar conversion yields, at low to modest enzyme loadings, and also produced high sugar concentration syrups at high initial insoluble solid loadings. The sugar syrups derived from corn stover are highly fermentable due to low concentrations of fermentation inhibitors. The objective of this work is to evaluate the economic feasibility of the DDR process through a techno-economic analysis (TEA). A large array of experiments designed using a response surface methodology was carried out to investigate the two major cost-driven operational parameters of the novel DDR process: refining energy and enzyme loadings. The boundary conditions for refining energy (128-468 kWh/ODMT), cellulase (Novozyme's CTec3) loading (11.6-28.4 mg total protein/g of cellulose), and hemicellulase (Novozyme's HTec3) loading (0-5 mg total protein/g of cellulose) were chosen to cover the most commercially practical operating conditions. The sugar and ethanol yields were modeled with good adequacy, showing a positive linear correlation between those yields and refining energy and enzyme loadings. The ethanol yields ranged from 77 to 89 gallons/ODMT of corn stover. The minimum sugar selling price (MSSP) ranged from $0.191 to $0.212 per lb of 50 % concentrated monomeric sugars, while the minimum ethanol selling price (MESP) ranged from $2.24 to $2.54 per gallon of ethanol. The DDR process concept is evaluated for economic feasibility through TEA. The MSSP and MESP of the DDR process falls within a range similar to that found with the deacetylation/dilute acid pretreatment process modeled in NREL's 2011 design report. The DDR process is

  18. A laboratory device for evaluation and study in the filed of ultrasonic transducers

    International Nuclear Information System (INIS)

    Vasiliu, S.

    1978-12-01

    A laboratory device for evaluation of the ultrasonic transducers, in view of adequate selection according to the testing requirements is presented. Recordings of ultrasonic beam of some transducers delivered as being of the same type are presented, showing important departures from specifications of the characteristics. Some of transducers evaluated have not been found acceptable for NDT in the nuclear field. (author)

  19. Evaluation of pressure tuning of enzymes

    DEFF Research Database (Denmark)

    Naghshineh, Mahsa

    and high energy consumption. Therefore, searching for an environmentally friendly method of pectin extraction is a task for science and industry. Employment of hydrolytic enzymes may represent a green approach to obtain intact pectin polymer. However, the low stability/activity of enzymes, and low polymer...... yield of enzymatic extraction limits the application of enzyme in pectin production. There is evidence that emerging technology of high hydrostatic pressure processing can result in stabilization and activation of some enzymes. Therefore, the use of high hydrostatic pressure in combination with enzyme...... (cellulase/xylanase: 50/0, 50/25, 50/50, 25/50, and 0/50 U/g lime peel) at ambient pressure, 100 and 200 MPa were used to extract pectin from dried lime peel waste. It was found that pressure level, type and concentration of enzyme significantly influenced pectin yield and degree of esterification (DE...

  20. Oral administration of thymoquinone mitigates the effect of cisplatin on brush border membrane enzymes, energy metabolism and antioxidant system in rat intestine.

    Science.gov (United States)

    Shahid, Faaiza; Farooqui, Zeba; Abidi, Subuhi; Parwez, Iqbal; Khan, Farah

    2017-10-01

    Cisplatin (CP) is a widely used chemotherapeutic agent that elicits severe gastrointestinal toxicity. Nigella sativa, a member of family Ranunculaceae, is one of the most revered medicinal plant known for its numerous health benefits. Thymoquinone (TQ), a major bioactive component derived from the volatile oil of Nigella sativa seeds, has been shown to improve gastrointestinal functions in animal models of acute gastric/intestinal injury. In view of this, the aim of the present study was to investigate the protective effect of TQ on CP induced toxicity in rat intestine and to elucidate the mechanism underlying these effects. Rats were divided into four groups viz. control, CP, TQ and CP+TQ. Animals in CP+TQ and TQ groups were orally administered TQ (1.5mg/kg bwt) with and without a single intraperitoneal dose of CP (6mg/kg bwt) respectively. The effect of TQ was determined on CP induced alterations in the activities of brush border membrane (BBM), carbohydrate metabolism, and antioxidant defense enzymes in rat intestine. TQ administration significantly mitigated CP induced decline in the specific activities of BBM marker enzymes, both in the mucosal homogenates and in the BBM vesicles (BBMV) prepared from intestinal mucosa. Furthermore, TQ administration restored the redox and metabolic status of intestinal mucosal tissue in CP treated rats. The biochemical results were supported by histopathological findings that showed extensive damage to intestine in CP treated rats and markedly preserved intestinal histoarchitecture in CP and TQ co-treated group. The biochemical and histological data suggest a protective effect of TQ against CP-induced gastrointestinal damage. Thus, TQ may have a potential for clinical application to counteract the accompanying gastrointestinal toxicity in CP chemotherapy. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  1. Valores energéticos do farelo de arroz integral suplementado com complexos enzimáticos para frangos de corte Energy values of whole rice bran supplemented with enzymes complexes for broilers

    Directory of Open Access Journals (Sweden)

    Renato Alberto Giacometti

    2003-06-01

    Full Text Available Este experimento foi realizado com o objetivo de estudar o efeito de enzimas carboidrases exógenas com atividade xilanase sobre a energia metabolizável aparente (EMA e aparente corrigida (EMAn do farelo de arroz integral (FAI. As enzimas carboidrases com atividade xilanase utilizadas foram as da marca comercial Rovabio TM Excel AP, Allzyme Rice e Ronozyme WX, denominadas, respectivamente, neste trabalho, de enzimas A, B, e C. Foram utilizadas 240 aves de corte da linhagem Coob, com 21 dias de idade, alojadas em gaiolas metálicas com bandejas coletoras de excretas instaladas em uma sala de metabolismo com ambiente controlado. O delineamento foi inteiramente casualizado, constituído por 4 dietas-referência e 4 dietas-teste e 6 repetições, totalizando 48 parcelas com 5 aves cada uma. As dietas-referência e as dietas-teste estudadas foram as seguintes: Dieta-referência à base de milho, farelo de soja, vitaminas e minerais (DR; DR + enzima A; DR + enzima B; DR + enzima C; 70% de DR + 30% de FAI; 70% de DR + 30% de FAI + enzima A; 70% de DR + 30% de FAI + enzima B e 70% de DR + 30% de FAI + enzima C. Utilizou-se o método de coleta total de excretas (Sibbald & Slinger, 1963 durante 5 dias em cada unidade experimental, precedido de 5 dias de adaptação das aves às dietas. As determinações de EMA e EMAn foram realizadas conforme metodologia de Matterson et al. (1965. A EMAn do FAI foi de 2897 kcal/kg de MS. Com o uso das enzimas carboidrases, o melhor valor de EMAn do FAI foi obtido quando utilizou-se a enzima C, sendo de 3083 kcal/kg de MS, com um aumento percentual de 6,4%. A dieta-referência que recebeu a adição da enzima C teve sua EMAn aumentada, o que não ocorreu com a utilização das outras carboidrases.An experiment was conducted to study the effect of exogen carbohydrase enzymes with xylanase activity on the apparent metabolizable energy (AME and apparent corrected metabolizable energy (AMEn of whole rice bran (WRB. The

  2. Enzyme inhibition by iminosugars

    DEFF Research Database (Denmark)

    López, Óscar; Qing, Feng-Ling; Pedersen, Christian Marcus

    2013-01-01

    Imino- and azasugar glycosidase inhibitors display pH dependant inhibition reflecting that both the inhibitor and the enzyme active site have groups that change protonation state with pH. With the enzyme having two acidic groups and the inhibitor one basic group, enzyme-inhibitor complexes...

  3. Measurement of vehicle-load using capacitance and acceleration transducers

    International Nuclear Information System (INIS)

    Yang, S; Yang, W; Yang, Y

    2007-01-01

    Over-loading is a common problem in some developing countries. Currently, large and fixed measurement systems are used to measure the load of vehicles travelling on highways. This paper presents an on-vehicle measuring device, which is based on measurement of change in capacitance due to variation in distance between electrodes mounted on vehicles. The on-vehicle leaf springs are used as a key part of the weighing transducer. Acceleration transducers are used to measure the vehicle's forward and the vertical accelerations. A feature of this on-vehicle measuring device is that it can provide both static and dynamic load measurements. The drivers can check the load in the cab, and the highway inspectors can check the load at any time and any place through radio communication, thus identifying over-loaded vehicles

  4. W-Band Circularly Polarized TE11 Mode Transducer

    Science.gov (United States)

    Zhan, Mingzhou; He, Wangdong; Wang, Lei

    2018-06-01

    This paper presents a balanced sidewall exciting approach to realize the circularly polarized TE11 mode transducer. We used a voltage vector transfer matrix to establish the relationship between input and output vectors, then we analyzed amplitude and phase errors to estimate the isolation of degenerate mode. A mode transducer with a sidewall exciter was designed based on the results. In the 88-100 GHz frequency range, the simulated axial ratio is less than 1.05 and the isolation of linearly polarization TE11 mode is higher than 30 dBc. In back-to-back measurements, the return loss is generally greater than 20 dB with a typical insertion loss of 1.2 dB. Back-to-back transmission measurements are in excellent agreement with simulations.

  5. The copying power of one-state tree transducers

    DEFF Research Database (Denmark)

    Engelfriet, Joost; Skyum, Sven

    1982-01-01

    One-state deterministic top-down tree transducers (or, tree homomorphisms) cannot handle “prime copying,” i.e., their class of output (string) languages is not closed under the operation L → {$(w$)f(n) short parallel w ε L, f(n) greater-or-equal, slanted 1}, where f is any integer function whose...... range contains numbers with arbitrarily large prime factors (such as a polynomial). The exact amount of nonclosure under these copying operations is established for several classes of input (tree) languages. These results are relevant to the extended definable (or, restricted parallel level) languages......, to the syntax-directed translation of context-free languages, and to the tree transducer hierarchy....

  6. Transducers for providing an electrical signal representative of physical movement

    International Nuclear Information System (INIS)

    Duncombe, E.; Roach, P.F.

    1985-01-01

    A transducer for use in hostile environments has an externally threaded rod slidable in an internally threaded tube. The threads of rod and tube are of two-start form and define slots in which inductively coupled mineral insulated conductors are located, the conductors being of hairpin form secured at the ends of the rod and tube at the hairpin bend with the hairpin tails in the slots. End diaphragms make a sealed transducer in which the rod can move axially relative to the tube by one half of one pitch of the threads without straining the diaphragms. In a modification rod and tube are arranged to rotate relative to each other up to +-180 0 which effectively also causes a one half pitch movement of the conductors. (author)

  7. Capacitive micromachined ultrasonic transducers for medical imaging and therapy

    International Nuclear Information System (INIS)

    Khuri-Yakub, Butrus T; Oralkan, Ömer

    2011-01-01

    Capacitive micromachined ultrasonic transducers (CMUTs) have been subject to extensive research for the last two decades. Although they were initially developed for air-coupled applications, today their main application space is medical imaging and therapy. This paper first presents a brief description of CMUTs, their basic structure and operating principles. Our progression of developing several generations of fabrication processes is discussed with an emphasis on the advantages and disadvantages of each process. Monolithic and hybrid approaches for integrating CMUTs with supporting integrated circuits are surveyed. Several prototype transducer arrays with integrated front-end electronic circuits we developed and their use for 2D and 3D, anatomical and functional imaging, and ablative therapies are described. The presented results prove the CMUT as a micro-electro-mechanical systems technology for many medical diagnostic and therapeutic applications

  8. Capacitive micromachined ultrasonic transducers for medical imaging and therapy.

    Science.gov (United States)

    Khuri-Yakub, Butrus T; Oralkan, Omer

    2011-05-01

    Capacitive micromachined ultrasonic transducers (CMUTs) have been subject to extensive research for the last two decades. Although they were initially developed for air-coupled applications, today their main application space is medical imaging and therapy. This paper first presents a brief description of CMUTs, their basic structure, and operating principles. Our progression of developing several generations of fabrication processes is discussed with an emphasis on the advantages and disadvantages of each process. Monolithic and hybrid approaches for integrating CMUTs with supporting integrated circuits are surveyed. Several prototype transducer arrays with integrated frontend electronic circuits we developed and their use for 2-D and 3-D, anatomical and functional imaging, and ablative therapies are described. The presented results prove the CMUT as a MEMS technology for many medical diagnostic and therapeutic applications.

  9. Electromechanical modelling of tapered ionic polymer metal composites transducers

    Directory of Open Access Journals (Sweden)

    Rakesha Chandra Dash

    2016-09-01

    Full Text Available Ionic polymer metal composites (IPMCs are relatively new smart materials that exhibit a bidirectional electromechanical coupling. IPMCs have large number of important engineering applications such as micro robotics, biomedical devices, biomimetic robotics etc. This paper presents a comparison between tapered and uniform cantilevered Nafion based IPMCs transducer. Electromechanical modelling is done for the tapered beam. Thickness can be varied according to the requirement of force and deflection. Numerical results pertaining to the force and deflection characteristics of both type IPMCs transducer are obtained. It is shown that the desired amount of force and deflections for tapered IPMCs can be achieved for a given voltage. Different fixed end (t0 and free end (t1 thickness values have been taken to justify the results using MATLAB.

  10. Graphene-metallic nanocomposites as modifiers in electrochemical glucose biosensor transducers

    Science.gov (United States)

    Altuntas, Derya Bal; Tepeli, Yudum; Anik, Ulku

    2016-09-01

    Graphene sheets and three different graphene-metallic nanocomposites including graphene-copper (graphene-Cu), graphene-nickel (graphene-Ni) and graphene-platinum (graphene-Pt) were prepared and characterized in the first place. Then the electrochemical performances of these nanocomposites were tested in glucose biosensor transducers, which were formed by combining these metallic nanocomposites with glucose oxidase enzyme and glassy carbon paste electrode (GCPE). This is the first work that includes the usage of these graphene-Me nanocomposites as a part of glucose biosensor transducer. Fabricated amperometric biosensors linear ranges were obtained as follow: For the plain graphene, the linear range was found in the concentration range between 50 μM and 800 μM with the RSD (n = 3 for 50 μM glucose) value of 12.86% and LOD value of 7.2 μM. For graphene-Pt modified glucose biosensor, the linear range was between 10 μM and 600 μM with the RSD (n = 3 for 50 μM glucose) value of 3.45% and LOD value of 3.06 μM. In the case of graphene-Ni modified glucose biosensor, the values were 25 μM to 600 μM with the RSD (n = 3 for 50 μM glucose) value of 8.76% and LOD value of 24.71 μM and for graphene-Cu modified glucose biosensor linear range was 25 μM to 400 μM with the RSD (n = 3 for 50 μM glucose) value of 3.93% and LOD value of 2.87 μM.

  11. Nonlinear electromechanical response of the ferroelectret ultrasonic transducers

    Czech Academy of Sciences Publication Activity Database

    Döring, J.; Bovtun, Viktor; Bartusch, J.; Erhard, A.; Kreutzbruck, M.; Yakymenko, Y.

    2010-01-01

    Roč. 100, č. 2 (2010), 479-485 ISSN 0947-8396 R&D Projects: GA ČR GAP204/10/0616; GA ČR(CZ) GA202/09/0682 Institutional research plan: CEZ:AV0Z10100520 Keywords : piezoelectric * ferroelectret * transducer * ultrasonic Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 1.765, year: 2010

  12. Application of digital PWM technology in current transducers

    International Nuclear Information System (INIS)

    Liu Huifang; Hu Zhimin; Li Rui

    2012-01-01

    With the development of DSP technology and mature use of PID technology,, a new program for DC or AC signal measurement is proposed. Combined with the DSP chip timer module and PID algorithm, PWM signals are generated to control the feedback circuit for the compensation current. Finally the measured current value can be obtained according to the ampere-turns compensation current and the measured current. Studies have shown that this technology enables new current transducers have high stability. (authors)

  13. Characterization of HIFU transducers designed for sonochemistry application: Acoustic streaming.

    Science.gov (United States)

    Hallez, L; Touyeras, F; Hihn, J-Y; Bailly, Y

    2016-03-01

    Cavitation distribution in a High Intensity Focused Ultrasound sonoreactors (HIFU) has been extensively described in the recent literature, including quantification by an optical method (Sonochemiluminescence SCL). The present paper provides complementary measurements through the study of acoustic streaming generated by the same kind of HIFU transducers. To this end, results of mass transfer measurements (electrodiffusional method) were compared to optical method ones (Particle Image Velocimetry). This last one was used in various configurations: with or without an electrode in the acoustic field in order to have the same perturbation of the wave propagation. Results show that the maximum velocity is not located at the focal but shifted near the transducer, and that this shift is greater for high powers. The two cavitation modes (stationary and moving bubbles) are greatly affect the hydrodynamic behavior of our sonoreactors: acoustic streaming and the fluid generated by bubble motion. The results obtained by electrochemical measurements show the same low hydrodynamic activity in the transducer vicinity, the same shift of the active focal toward the transducer, and the same absence of activity in the post-focal axial zone. The comparison with theoretical Eckart's velocities (acoustic streaming in non-cavitating media) confirms a very high activity at the "sonochemical focal", accounted for by wave distortion, which induced greater absorption coefficients. Moreover, the equivalent liquid velocities are one order of magnitude larger than the ones measured by PIV, confirming the enhancement of mass transfer by bubbles oscillation and collapse close to the surface, rather than from a pure streaming effect. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. An all-optical fiber optic photoacoustic transducer

    Science.gov (United States)

    Thathachary, Supriya V.; Motameni, Cameron; Ashkenazi, Shai

    2018-02-01

    A highly sensitive fiber-optic Fabry-Perot photoacoustic transducer is proposed in this work. The transducer will consist of separate transmit and receive fibers. The receiver will be composed of a Fabry-Perot Ultrasound sensor with a selfwritten waveguide with all-optical ultrasound detection with high sensitivity. In previous work, we have shown an increase in resonator Q-factor from 1900 to 3200 for a simulated Fabry-Perot ultrasound detector of 45 μm thickness upon including a waveguide to limit lateral power losses. Subsequently, we demonstrated a prototype device with 30nm gold mirrors and a cavity composed of the photosensitive polymer Benzocyclobutene. This 80 µm thick device showed an improvement in its Q-factor from 2500 to 5200 after a selfaligned waveguide was written into the cavity using UV exposure. Current work uses a significantly faster fabrication technique using a combination of UV-cured epoxies for the cavity medium, and the waveguide within it. This reduces the fabrication time from several hours to a few minutes, and significantly lowers the cost of fabrication. We use a dip-coating technique to deposit the polymer layer. Future work will include the use of Dielectric Bragg mirrors in place of gold to achieve better reflectivity, thereby further improving the Q-factor of the device. The complete transducer presents an ideal solution for intravascular imaging in cases where tissue differentiation is desirable, an important feature in interventional procedures where arterial perforation is a risk. The final design proposed comprises the transducer within a guidewire to guide interventions for Chronic Total Occlusions, a disease state for which there are currently no invasive imaging options.

  15. Finite element analysis of hysteresis effects in piezoelectric transducers

    Science.gov (United States)

    Simkovics, Reinhard; Landes, Hermann; Kaltenbacher, Manfred; Hoffelner, Johann; Lerch, Reinhard

    2000-06-01

    The design of ultrasonic transducers for high power applications, e.g. in medical therapy or production engineering, asks for effective computer aided design tools to analyze the occurring nonlinear effects. In this paper the finite-element-boundary-element package CAPA is presented that allows to model different types of electromechanical sensors and actuators. These transducers are based on various physical coupling effects, such as piezoelectricity or magneto- mechanical interactions. Their computer modeling requires the numerical solution of a multifield problem, such as coupled electric-mechanical fields or magnetic-mechanical fields as well as coupled mechanical-acoustic fields. With the reported software environment we are able to compute the dynamic behavior of electromechanical sensors and actuators by taking into account geometric nonlinearities, nonlinear wave propagation and ferroelectric as well as magnetic material nonlinearities. After a short introduction to the basic theory of the numerical calculation schemes, two practical examples will demonstrate the applicability of the numerical simulation tool. As a first example an ultrasonic thickness mode transducer consisting of a piezoceramic material used for high power ultrasound production is examined. Due to ferroelectric hysteresis, higher order harmonics can be detected in the actuators input current. Also in case of electrical and mechanical prestressing a resonance frequency shift occurs, caused by ferroelectric hysteresis and nonlinear dependencies of the material coefficients on electric field and mechanical stresses. As a second example, a power ultrasound transducer used in HIFU-therapy (high intensity focused ultrasound) is presented. Due to the compressibility and losses in the propagating fluid a nonlinear shock wave generation can be observed. For both examples a good agreement between numerical simulation and experimental data has been achieved.

  16. Review of piezoelectric micromachined ultrasonic transducers and their applications

    International Nuclear Information System (INIS)

    Jung, Joontaek; Lee, Wonjun; Kang, Woojin; Shin, Eunjung; Choi, Hongsoo; Ryu, Jungho

    2017-01-01

    In recent decades, micromachined ultrasonic transducers (MUTs) have been investigated as an alternative to conventional piezocomposite ultrasonic transducers, primarily due to the advantages that microelectromechanical systems provide. Miniaturized ultrasonic systems require ultrasonic transducers integrated with complementary metal-oxide-semiconductor circuits. Hence, piezoelectric MUTs (pMUTs) and capacitive MUTs (cMUTs) have been developed as the most favorable solutions. This paper reviews the basic equations to understand the characteristics of thin-film-based piezoelectric devices and presents recent research on pMUTs, including current approaches and limitations. Methods to improve the coupling coefficient of pMUTs are also investigated, such as device structure, materials, and fabrication techniques. The device structure improvements include multielectrode pMUTs, partially clamped boundary conditions, and 3D pMUTs (curved and domed types), where the latter can provide an electromechanical coupling coefficient of up to 45%. The piezoelectric coefficient ( e 31 ) can be increased by controlling the crystal texture (seed layer of γ -Al 2 O 3 ), using single-crystal (PMN-PT) materials, or control of residual stresses (using SiO 2 layer). Arrays of pMUTs can be implemented for various applications including intravascular ultrasound, fingerprint sensors, rangefinders in air, and wireless power supply systems. pMUTs are expected to be an ideal solution for applications such as mobile biometric security (fingerprint sensors) and rangefinders due to their superior power efficiency and compact size. (topical review)

  17. Development of ultrasonic testing equipment incorporating electromagnetic acoustic transducer

    International Nuclear Information System (INIS)

    Sato, Michio; Kimura, Motohiko; Okano, Hideharu; Miyazawa, Tatsuo; Nagase, Koichi; Ishikawa, Masaaki

    1989-01-01

    An ultrasonic testing equipment for use in in-service inspection of nuclear power plant piping has been developed, which comprises an angle-beam electromagnetic acoustic transducer mounted on a vehicle for scanning the piping surface to be inspected. The transducer functions without direct contact with the piping surface through couplant, and the vehicle does not require a guide track installed on the piping surface, being equipped with magnetic wheels that adhere to the piping material, permitting it to travel along the circumferential weld joint of a carbon steel pipe. The equipment thus dispenses with the laborious manual work involved in preparing the piping for inspection, such as removal of protective coating, surface polishing and installation of guide track and thereby considerably reduces the duration of inspection. The functioning principle and structural features of the transducer and vehicle are described, together with the results of trial operation of a prototype unit, which proved a 1mm deep notch cut on a test piece of 25mm thick carbon steel plate to be locatable with an accuracy of ±2mm. (author)

  18. Efficient Driving of Piezoelectric Transducers Using a Biaxial Driving Technique.

    Directory of Open Access Journals (Sweden)

    Samuel Pichardo

    Full Text Available Efficient driving of piezoelectric materials is desirable when operating transducers for biomedical applications such as high intensity focused ultrasound (HIFU or ultrasound imaging. More efficient operation reduces the electric power required to produce the desired bioeffect or contrast. Our preliminary work [Cole et al. Journal of Physics: Condensed Matter. 2014;26(13:135901.] suggested that driving transducers by applying orthogonal electric fields can significantly reduce the coercivity that opposes ferroelectric switching. We present here the experimental validation of this biaxial driving technique using piezoelectric ceramics typically used in HIFU. A set of narrow-band transducers was fabricated with two sets of electrodes placed in an orthogonal configuration (following the propagation and the lateral mode. The geometry of the ceramic was chosen to have a resonance frequency similar for the propagation and the lateral mode. The average (± s.d. resonance frequency of the samples was 465.1 (± 1.5 kHz. Experiments were conducted in which each pair of electrodes was driven independently and measurements of effective acoustic power were obtained using the radiation force method. The efficiency (acoustic/electric power of the biaxial driving method was compared to the results obtained when driving the ceramic using electrodes placed only in the pole direction. Our results indicate that the biaxial method increases efficiency from 50% to 125% relative to the using a single electric field.

  19. Tungsten Oxide Photonic Crystals as Optical Transducer for Gas Sensing.

    Science.gov (United States)

    Amrehn, Sabrina; Wu, Xia; Wagner, Thorsten

    2018-01-26

    Some metal oxide semiconductors, such as tungsten trioxide or tin dioxide, are well-known as resistive transducers for gas sensing and offer high sensitivities down to the part per billion level. Electrical signal read-out, however, limits the information obtained on the electronic properties of metal oxides to a certain frequency range and its application because of the required electrical contacts. Therefore, a novel approach for building an optical transducer for gas reactions utilizing metal oxide photonic crystals is presented here. By the rational design of the structure and composition it is possible to synthesize a functional material which allows one to obtain insight into its electronic properties in the optical frequency range with simple experimental measures. The concept is demonstrated by tungsten trioxide inverse opal structure as optical transducer material for hydrogen sensing. The sensing behavior is analyzed in a temperature range from room temperature to 500 °C and in a wide hydrogen concentration range (3000 ppm to 10%). The sensing mechanism is mainly the refractive index change resulting from hydrogen intercalation in tungsten trioxide, but the back reaction has also impact on the optical properties of this system. Detailed chemical reaction studies provide suggestions for specific sensing conditions.

  20. Ergonomic design and evaluation of a diagnostic ultrasound transducer holder.

    Science.gov (United States)

    Ghasemi, Mohamad Sadegh; Hosseinzadeh, Payam; Zamani, Farhad; Ahmadpoor, Hossein; Dehghan, Naser

    2017-12-01

    Work-related musculoskeletal disorders (WMSDs) are injuries and disorders that affect the body's movement and musculoskeletal system. Awkward postures represent one of the major ergonomic risk factors that cause WMSDs among sonographers while working with an ultrasound transducer. This study aimed to design and evaluate a new holder for the ultrasound transducer. In the first phase a new holder was designed for the transducer, considering design principles. Evaluation of the new holder was then carried out by electrogoniometry and a locally perceived discomfort (LPD) scale. The application of design principles to the new holder resulted in an improvement of wrist posture and comfort. Wrist angles in extension, flexion, radial deviation and ulnar deviation were lower with utilization of the new holder. The severity of discomfort based on the LPD method in the two modes of work with and without the new holder was reported with values of 1.3 and 1.8, respectively (p ergonomics design principles was effective in minimizing wrist deviation and increasing comfort while working with the new holder.

  1. Review of piezoelectric micromachined ultrasonic transducers and their applications

    Science.gov (United States)

    Jung, Joontaek; Lee, Wonjun; Kang, Woojin; Shin, Eunjung; Ryu, Jungho; Choi, Hongsoo

    2017-11-01

    In recent decades, micromachined ultrasonic transducers (MUTs) have been investigated as an alternative to conventional piezocomposite ultrasonic transducers, primarily due to the advantages that microelectromechanical systems provide. Miniaturized ultrasonic systems require ultrasonic transducers integrated with complementary metal-oxide-semiconductor circuits. Hence, piezoelectric MUTs (pMUTs) and capacitive MUTs (cMUTs) have been developed as the most favorable solutions. This paper reviews the basic equations to understand the characteristics of thin-film-based piezoelectric devices and presents recent research on pMUTs, including current approaches and limitations. Methods to improve the coupling coefficient of pMUTs are also investigated, such as device structure, materials, and fabrication techniques. The device structure improvements include multielectrode pMUTs, partially clamped boundary conditions, and 3D pMUTs (curved and domed types), where the latter can provide an electromechanical coupling coefficient of up to 45%. The piezoelectric coefficient (e 31) can be increased by controlling the crystal texture (seed layer of γ-Al2O3), using single-crystal (PMN-PT) materials, or control of residual stresses (using SiO2 layer). Arrays of pMUTs can be implemented for various applications including intravascular ultrasound, fingerprint sensors, rangefinders in air, and wireless power supply systems. pMUTs are expected to be an ideal solution for applications such as mobile biometric security (fingerprint sensors) and rangefinders due to their superior power efficiency and compact size.

  2. A process chain for integrating piezoelectric transducers into aluminum die castings to generate smart lightweight structures

    Science.gov (United States)

    Stein, Stefan; Wedler, Jonathan; Rhein, Sebastian; Schmidt, Michael; Körner, Carolin; Michaelis, Alexander; Gebhardt, Sylvia

    The application of piezoelectric transducers to structural body parts of machines or vehicles enables the combination of passive mechanical components with sensor and actuator functions in one single structure. According to Herold et al. [1] and Staeves [2] this approach indicates significant potential regarding smart lightweight construction. To obtain the highest yield, the piezoelectric transducers need to be integrated into the flux of forces (load path) of load bearing structures. Application in a downstream process reduces yield and process efficiency during manufacturing and operation, due to the necessity of a subsequent process step of sensor/actuator application. The die casting process offers the possibility for integration of piezoelectric transducers into metal structures. Aluminum castings are particularly favorable due to their high quality and feasibility for high unit production at low cost (Brunhuber [3], Nogowizin [4]). Such molded aluminum parts with integrated piezoelectric transducers enable functions like active vibration damping, structural health monitoring or energy harvesting resulting in significant possibilities of weight reduction, which is an increasingly important driving force of automotive and aerospace industry (Klein [5], Siebenpfeiffer [6]) due to increasingly stringent environmental protection laws. In the scope of those developments, this paper focuses on the entire process chain enabling the generation of lightweight metal structures with sensor and actuator function, starting from the manufacturing of piezoelectric modules over electrical and mechanical bonding to the integration of such modules into aluminum (Al) matrices by die casting. To achieve this challenging goal, piezoceramic sensors/actuator modules, so-called LTCC/PZT modules (LPM) were developed, since ceramic based piezoelectric modules are more likely to withstand the thermal stress of about 700 °C introduced by the casting process (Flössel et al., [7]). The

  3. Modeling transducer impulse responses for predicting calibrated pressure pulses with the ultrasound simulation program Field II

    DEFF Research Database (Denmark)

    Bæk, David; Jensen, Jørgen Arendt; Willatzen, Morten

    2010-01-01

    FIELD II is a simulation software capable of predicting the field pressure in front of transducers having any complicated geometry. A calibrated prediction with this program is, however, dependent on an exact voltage-to-surface acceleration impulse response of the transducer. Such impulse response...... is not calculated by FIELD II. This work investigates the usability of combining a one-dimensional multilayer transducer modeling principle with the FIELD II software. Multilayer here refers to a transducer composed of several material layers. Measurements of pressure and current from Pz27 piezoceramic disks...... transducer model and the FIELD II software in combination give good agreement with measurements....

  4. Research and development of in-core transducers at the CIAE

    International Nuclear Information System (INIS)

    Huang Yucai; Liu Yupu; Jia Guozhen; Liu Lianping

    1996-01-01

    In this paper, R and D of in-core transducers at the CIAE are briefly summarized. With the construction and commissioning of PWR nuclear power plant in China, fuel rod behaviour need to be studied carefully. As conventional transducers cannot meet the requirements of in-core applications, R and D of in-core transducers are developed. Since 1980's, several kinds of in-core transducers have been successfully fabricated and tested under the conditions simulating PWR. At present, in-pile tests of the transducers combining with the studies of individual behaviour of PWR fuel rod are being planned at the CIAE. (author). 11 refs, 12 figs, 4 tabs

  5. Positioning calibration apparatus for transducers employed in nuclear reactor vessel inspection apparatus

    International Nuclear Information System (INIS)

    Elsner, H.J.

    1981-01-01

    The invention provides a calibration apparatus suitable for verifying the position and orientation of transducers used in reactor vessel ultrasonic inspection. The apparatus includes moveable mounting means which secures a transducer within the tank in its normal inspection orientation. A drive is also provided for moving the transducer in the tank relative to a target. The target is slidably positioned in the tank at a distance from the transducer which is selected to avoid the distortion effects in the near field of the transducer. The drive mechanism may be provided with graduated indicia of travel, or a scale may be affixed to the side of the tank. (L.L.)

  6. Full-scale Mark II CRT program: dynamic response evaluation test of pressure transducers

    International Nuclear Information System (INIS)

    Kukita, Yutaka; Namatame, Ken; Takeshita, Isao; Shiba, Masayoshi

    1982-12-01

    A dynamic response evaluation test of pressure transducers was conducted in support of the JAERI Full-Scale Mark II CRT (Containment Response Test) Program. The test results indicated that certain of the cavity-type transducers used in the early blowdown test had undesirable response characteristics. The transducer mounting scheme was modified to avoid trapping of air bubbles in the pressure transmission tubing attached to the transducers. The dynamic response of the modified transducers was acceptable within the frequency range of 200 Hz. (author)

  7. 3D-printed adaptive acoustic lens as a disruptive technology for transcranial ultrasound therapy using single-element transducers

    Science.gov (United States)

    Maimbourg, Guillaume; Houdouin, Alexandre; Deffieux, Thomas; Tanter, Mickael; Aubry, Jean-François

    2018-01-01

    The development of multi-element arrays for better control of the shape of ultrasonic beams has opened the way for focusing through highly aberrating media, such as the human skull. As a result, the use of brain therapy with transcranial-focused ultrasound has rapidly grown. Although effective, such technology is expensive. We propose a disruptive, low-cost approach that consists of focusing a 1 MHz ultrasound beam through a human skull with a single-element transducer coupled with a tailored silicone acoustic lens cast in a 3D-printed mold and designed using computed tomography-based numerical acoustic simulation. We demonstrate on N  =  3 human skulls that adding lens-based aberration correction to a single-element transducer increases the deposited energy on the target 10 fold.

  8. Study of the temperature rise induced by a focusing transducer with a wide aperture angle on biological tissue containing ribs

    International Nuclear Information System (INIS)

    Wang Xin; Lin Jiexing; Liu Xiaozhou; Liu Jiehui; Gong Xiufen

    2016-01-01

    We used the spheroidal beam equation to calculate the sound field created by focusing a transducer with a wide aperture angle to obtain the heat deposition, and then we used the Pennes bioheat equation to calculate the temperature field in biological tissue with ribs and to ascertain the effects of rib parameters on the temperature field. The results show that the location and the gap width between the ribs have a great influence on the axial and radial temperature rise of multilayer biological tissue. With a decreasing gap width, the location of the maximum temperature rise moves forward; as the ribs are closer to the transducer surface, the sound energy that passes through the gap between the ribs at the focus decreases, the maximum temperature rise decreases, and the location of the maximum temperature rise moves forward with the ribs. (paper)

  9. Calculation of wideband ultrasonic fields radiated by immersed transducers into solids

    International Nuclear Information System (INIS)

    Lhemery, A.; Calmon, P.; Mephane, M.

    1996-01-01

    In ultrasonic nondestructive testing (NDT), configurations of immersion techniques where transducers radiate through non-planar interfaces are often encountered, e.g., pipe inspection where the probe can be scanned either inside or outside the pipe. When local radii of curvature are far larger that typical wave paths in the coupling fluid and into the piece, field predictions can often be made assuming a plane interface. For smaller radii, such an approximation is not valid. The model developed at the French Atomic ENergy Commission (CEA) to predict ultrasonic fields radiated by wideband transducers through liquid-interfaces (called Champ-Sons) is based on a modification of the Rayleigh integral to take account of refraction. It is derived under the geometrical optics approximation (GO) which introduces two factors: the transmission coefficient between the two media of elementary contributions from source-points to field-points and the so-called 'divergence factor' of the transmitted rays (denoted by DF), accounting for the principal radii of curvature of the retransmitted rays (denoted by DF), accounting for the principal radii of curvature of the refracted wave fronts (initially spherical in the coupling medium). (authors)

  10. Choice of primary transducers of beam parameters for measuring and control systems of charged particle accelerators

    International Nuclear Information System (INIS)

    Rybin, V.M.

    1981-01-01

    Investigations on classification of primary transducers (pT) of the main parameters of charged particle beams are conducted for development of the common series on the base of program- controlled module systems for measuring the parameters of charged particle beams. The PT classification is exercised by: the physical principle of single transformation, the degree of effect on the beam, principle of operation, design, performance, location. It is shown that the optimal choice of PT and their parameters should be necessarily executed in several stages: estimation of the limiting possibilities of PT; choice of PT by time and metrological characteristics as well as sensitivity for the determined operation conditions; choice of the PT by the degree of effect on the beam: choice of the PT type with account of its design performance and location, determination of PT parameters with account of possibility of information, energy and design compatibility of the used standard. The classification results of magnetoinduction and acoustic transducers have shown that the number of their modifications does not exceed 100 [ru

  11. From research to production: field induced electro-mechanical polymer-transducer (Conference Presentation)

    Science.gov (United States)

    Kovacs, Gabor M.

    2017-04-01

    In the past decades the development of compliant dielectric materials, capable of storing high electric energy density, is the object of considerable research efforts for commercial applications. Compared to the widely used soft dielectrics as compliant insulators, only a small variety of commercially products based on dielectric polymer transducers are available on the market up to date. A whole bunch of research activities worldwide has created a lot of very useful knowledge; but many researchers have been faced to different obstacles to manufacture devices for demonstrations. However, building handy demonstrators is one of the most relevant action in order to attract the interest of decision makers of industrial companies. Moreover, low cost devices strictly require highly efficient production methods and facilities to become competitive on the market. This aspect contains the ultimate requirement especially for very high output rates and represents one of the major topic at most negotiations. All technological problems linked to this issue have been addressed only a little in the past R+D activities and are still widely not satisfactory solved. The present talk will provide an overview of the options for opening the door of industrial production of polymer transducers and the remaining obstacles to be solved for the next step. In particular, the most relevant actions to be taken for enabling high capacity production at very low cost will be discussed, which have an essential impact on the direction of future research activities.

  12. Development of ultrasound transducer diffractive field theory for nonlinear propagation-based imaging

    Science.gov (United States)

    Kharin, Nikolay A.

    2000-04-01

    In nonlinear ultrasound imaging the images are formed using the second harmonic energy generated due to the nonlinear nature of finite amplitude propagation. This propagation can be modeled using the KZK wave equation. This paper presents further development of nonlinear diffractive field theory based on the KZK equation and its solution by means of the slowly changing profile method for moderate nonlinearity. The analytical expression for amplitudes and phases of sum frequency wave are obtained in addition to the second harmonic wave. Also, the analytical expression for the relative curvature of the wave fronts of fundamental and second harmonic signals are derived. The media with different nonlinear properties and absorption coefficients were investigated to characterize the diffractive field of the transducer at medical frequencies. All expressions demonstrate good agreement with experimental results. The expressions are novel and provide an easy way for prediction of amplitude and phase structure of nonlinearly distorted field of a transducer. The sum frequency signal technique could be implemented as well as second harmonic technique to improve the quality of biomedical images. The results obtained are of importance for medical diagnostic ultrasound equipment design.

  13. A U-shaped linear ultrasonic motor using longitudinal vibration transducers with double feet.

    Science.gov (United States)

    Liu, Yingxiang; Liu, Junkao; Chen, Weishan; Shi, Shengjun

    2012-05-01

    A U-shaped linear ultrasonic motor using longitudinal vibration transducers with double feet was proposed in this paper. The proposed motor contains a horizontal transducer and two vertical transducers. The horizontal transducer includes two exponential shape horns located at the leading ends, and each vertical transducer contains one exponential shape horn. The horns of the horizontal transducer and the vertical transducer intersect at the tip ends where the driving feet are located. Longitudinal vibrations are superimposed in the motor and generate elliptical motions at the driving feet. The two vibration modes of the motor are discussed, and the motion trajectories of driving feet are deduced. By adjusting the structural parameters, the resonance frequencies of two vibration modes were degenerated. A prototype motor was fabricated and measured. Typical output of the prototype is no-load speed of 854 mm/s and maximum thrust force of 40 N at a voltage of 200 V(rms).

  14. Energy

    International Nuclear Information System (INIS)

    Meister, F.; Ott, F.

    2002-01-01

    This chapter gives an overview of the current energy economy in Austria. The Austrian political aims of sustainable development and climate protection imply a reorientation of the Austrian energy policy as a whole. Energy consumption trends (1993-1998), final energy consumption by energy carrier (indexed data 1993-1999), comparative analysis of useful energy demand (1993 and 1999) and final energy consumption of renewable energy sources by sector (1996-1999) in Austria are given. The necessary measures to be taken in order to reduce the energy demand and increased the use of renewable energy are briefly mentioned. Figs. 5. (nevyjel)

  15. Demonstration of TEG-powered wireless autonomous transducer solution for condition monitoring in industrial environment

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Ziyang; Patrascu, Mihai; Su, Jiale; Vullers, Ruud J.M. [imec the Netherlands, Eindhoven (Netherlands)

    2011-07-01

    Imec/Holst Centre focuses on the development of wireless autonomous transducer solution, which is poised to bring about huge impact in the sectors of health care, machinery, transportation and energy, etc. In this paper, we first showcase a TEG-powered demonstration for condition monitoring in industrial environment. Composing of sensor-actuator, front-end interface, digital signal processing unit and radio, the developed wireless sensor node can monitor the changing operating condition, i.e. the loading on a rolling-element bearing, on a rotating shaft. The use of a specially designed TEG, working in tandem with an energy storage device, can significantly improve the energy autonomy of the condition monitoring system as a whole. The different components in the demonstration are presented. Subsequently, the experimental results of vibration signature analysis are exhibited. On one hand, the presented demonstration sheds light on the huge potential of thermoelectric energy harvesting to achieve energy autonomy. On the other hand, it also points to the aspects that are in need of further development, namely miniaturization and cost reduction of energy harvesters. Aimed at the delivery of cost-effective miniaturized thermoelectric harvesting devices, imec/Holst Centre has been tackling with the relevant challenges by resorting to, but not limited to, its expertise in micromachining. An update on the latest research results is subsequently given with regard to various micromachined thermoelectric devices, fully fledged wearable TEGs with custom designed package and thermoelectric material property optimization. (orig.)

  16. Energy

    International Nuclear Information System (INIS)

    Meister, F.

    2001-01-01

    This chapter of the environmental control report deals with the environmental impact of energy production, energy conversion, atomic energy and renewable energy. The development of the energy consumption in Austria for the years 1993 to 1999 is given for the different energy types. The development of the use of renewable energy sources in Austria is given, different domestic heat-systems are compared, life cycles and environmental balance are outlined. (a.n.)

  17. Microbial production of raw starch digesting enzymes | Sun | African ...

    African Journals Online (AJOL)

    Raw starch digesting enzymes refer to enzymes that can act directly on raw starch granules below the gelatinization temperature of starch. With the view of energy-saving, a worldwide interest has been focused on raw starch digesting enzymes in recent years, especially since the oil crisis of 1973. Raw starch digesting ...

  18. Enzymes for improved biomass conversion

    Science.gov (United States)

    Brunecky, Roman; Himmel, Michael E.

    2016-02-02

    Disclosed herein are enzymes and combinations of the enzymes useful for the hydrolysis of cellulose and the conversion of biomass. Methods of degrading cellulose and biomass using enzymes and cocktails of enzymes are also disclosed.

  19. Immobilized enzymes and cells

    Energy Technology Data Exchange (ETDEWEB)

    Bucke, C; Wiseman, A

    1981-04-04

    This article reviews the current state of the art of enzyme and cell immobilization and suggests advances which might be made during the 1980's. Current uses of immobilized enzymes include the use of glucoamylase in the production of glucose syrups from starch and glucose isomerase in the production of high fructose corn syrup. Possibilities for future uses of immobilized enzymes and cells include the utilization of whey and the production of ethanol.

  20. Profiling the orphan enzymes

    Science.gov (United States)

    2014-01-01

    The emergence of Next Generation Sequencing generates an incredible amount of sequence and great potential for new enzyme discovery. Despite this huge amount of data and the profusion of bioinformatic methods for function prediction, a large part of known enzyme activities is still lacking an associated protein sequence. These particular activities are called “orphan enzymes”. The present review proposes an update of previous surveys on orphan enzymes by mining the current content of public databases. While the percentage of orphan enzyme activities has decreased from 38% to 22% in ten years, there are still more than 1,000 orphans among the 5,000 entries of the Enzyme Commission (EC) classification. Taking into account all the reactions present in metabolic databases, this proportion dramatically increases to reach nearly 50% of orphans and many of them are not associated to a known pathway. We extended our survey to “local orphan enzymes” that are activities which have no representative sequence in a given clade, but have at least one in organisms belonging to other clades. We observe an important bias in Archaea and find that in general more than 30% of the EC activities have incomplete sequence information in at least one superkingdom. To estimate if candidate proteins for local orphans could be retrieved by homology search, we applied a simple strategy based on the PRIAM software and noticed that candidates may be proposed for an important fraction of local orphan enzymes. Finally, by studying relation between protein domains and catalyzed activities, it appears that newly discovered enzymes are mostly associated with already known enzyme domains. Thus, the exploration of the promiscuity and the multifunctional aspect of known enzyme families may solve part of the orphan enzyme issue. We conclude this review with a presentation of recent initiatives in finding proteins for orphan enzymes and in extending the enzyme world by the discovery of new

  1. Development of a novel omnidirectional magnetostrictive transducer for plate applications

    Science.gov (United States)

    Vinogradov, Sergey; Cobb, Adam; Bartlett, Jonathan; Udagawa, Youichi

    2018-04-01

    The application of guided waves for the testing of plate-type structures has been recently investigated by a number of research groups due to the ability of guided waves to detect corrosion in remote and hidden areas. Guided wave sensors for plate applications can be either directed (i.e., the waves propagate in a single direction) or omnidirectional. Each type has certain advantages and disadvantages. Omnidirectional sensors can inspect large areas from a single location, but it is challenging to define where a feature is located. Conversely, directed sensors can be used to precisely locate an indication, but have no sensitivity to flaws away from the wave propagation direction. This work describes a newly developed sensor that combines the strengths of both sensor types to create a novel omnidirectional transducer. The sensor transduction is based on a custom magnetostrictive transducer (MsT). In this new probe design, a directed, plate-application MsT with known characteristics was incorporated into an automated scanner. This scanner rotates the directed MsT for data collection at regular intervals. Coupling of the transducer to the plate is accomplished using a shear wave couplant. The array of data that is received is used for compiling B-scans and imaging, utilizing a synthetic aperture focusing algorithm (SAFT). The performance of the probe was evaluated on a 0.5-inch thick carbon steel plate mockup with a surface area of over 100 square feet. The mockup had a variety of known anomalies representing localized and distributed pitting corrosion, gradual wall thinning, and notches of different depths. Experimental data was also acquired using the new probe on a retired storage tank with known corrosion damage. The performance of the new sensor and its limitations are discussed together with general directions in technology development.

  2. Enzymes - important players in green chemistry

    Directory of Open Access Journals (Sweden)

    Agata Tarczykowska

    2017-09-01

    Full Text Available Green chemistry has become a worldwide approach that leads to sustainable growth through application and development of its principles. A lot of work has to be put into designing new processes comprising of materials which do not emit pollutants to the atmosphere. Inventing new safer methods and finding less harmful products can be challenging. Enzymes are a great hope of scientists in the field of green chemistry. Enzymes as catalysts require mild conditions therefore it is a great way of saving resources such as energy or water. Processes with the use of enzymes have become more feasible by being more cost effective and eco friendly. Taking into account the benefits of green chemistry, enzyme biocatalysis has quickly replaced traditional chemical processes in several fields, and this substitution is going to reach even more areas because of new emerging technologies in enzyme engineering.

  3. Production of cellulolytic enzymes from ascomycetes

    DEFF Research Database (Denmark)

    Hansen, Gustav Hammerich; Lübeck, Mette; Frisvad, Jens Christian

    2015-01-01

    Optimizing production of cellulose degrading enzymes is of great interest in order to increase the feasibility of constructing biorefinery facilities for a sustainable supply of energy and chemical products. The ascomycete phylum has a large potential for the production of cellulolytic enzymes....... Although numerous enzymatic profiles have already been unraveled, the research has been covering only a limited number of species and genera, thus leaving many ascomycetes to be analyzed. Such analysis requires choosing appropriate media and cultivation methods that ensure enzyme profiles with high...... specificities and activities. However, the choice of media, cultivation methods and enzyme assays highly affect the enzyme activity profile observed. This review provides an overview of enzymatic profiles for several ascomycetes covering phylogenetically distinct genera and species. The profiles of cellulose...

  4. Design and analysis of fractional order seismic transducer for displacement and acceleration measurements

    Science.gov (United States)

    Veeraian, Parthasarathi; Gandhi, Uma; Mangalanathan, Umapathy

    2018-04-01

    Seismic transducers are widely used for measurement of displacement, velocity, and acceleration. This paper presents the design of seismic transducer in the fractional domain for the measurement of displacement and acceleration. The fractional order transfer function for seismic displacement and acceleration transducer are derived using Grünwald-Letnikov derivative. Frequency response analysis of fractional order seismic displacement transducer (FOSDT) and fractional order seismic acceleration transducer (FOSAT) are carried out for different damping ratio with the different fractional order, and the maximum dynamic measurement range is identified. The results demonstrate that fractional order seismic transducer has increased dynamic measurement range and less phase distortion as compared to the conventional seismic transducer even with a lower damping ratio. Time response of FOSDT and FOSAT are derived analytically in terms of Mittag-Leffler function, the effect of fractional behavior in the time domain is evaluated from the impulse and step response. The fractional order system is found to have significantly reduced overshoot as compared to the conventional transducer. The fractional order seismic transducer design proposed in this paper is illustrated with a design example for FOSDT and FOSAT. Finally, an electrical equivalent of FOSDT and FOSAT is considered, and its frequency response is found to be in close agreement with the proposed fractional order seismic transducer.

  5. LOFT liquid level transducer application techniques and measurement uncertainty

    International Nuclear Information System (INIS)

    Batt, D.L.; Biladeau, G.L.; Goodrich, L.D.; Nightingale, C.M.

    1979-01-01

    A conductivity sensitive liquid level transducer (LLT) has been designed and used successfully for determining whether steam or water is present in the Loss-of-Fluid Tests (LOFT) performed by EG and G Idaho, Inc., at the Idaho National Engineering Laboratory. The presence of steam or water is determined by establishing a discriminator level which is set manually. A computer program establishes the presence or absence of water for each data point taken. In addition to liquid level, the LLT is used for reactor vessel mass and volume calculations. The uncertainty in the liquid level is essentially the spacing of the LLT electrodes

  6. Capacitive micromachined ultrasonic transducer arrays as tunable acoustic metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Lani, Shane W., E-mail: shane.w.lani@gmail.com, E-mail: karim.sabra@me.gatech.edu, E-mail: levent.degertekin@me.gatech.edu; Sabra, Karim G. [George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 801Ferst Drive, Georgia 30332-0405 (United States); Wasequr Rashid, M.; Hasler, Jennifer [School of Electrical and Computer Engineering, Georgia Institute of Technology, Van Leer Electrical Engineering Building, 777 Atlantic Drive NW, Atlanta, Georgia 30332-0250 (United States); Levent Degertekin, F. [George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 801Ferst Drive, Georgia 30332-0405 (United States); School of Electrical and Computer Engineering, Georgia Institute of Technology, Van Leer Electrical Engineering Building, 777 Atlantic Drive NW, Atlanta, Georgia 30332-0250 (United States)

    2014-02-03

    Capacitive Micromachined Ultrasonic Transducers (CMUTs) operating in immersion support dispersive evanescent waves due to the subwavelength periodic structure of electrostatically actuated membranes in the array. Evanescent wave characteristics also depend on the membrane resonance which is modified by the externally applied bias voltage, offering a mechanism to tune the CMUT array as an acoustic metamaterial. The dispersion and tunability characteristics are examined using a computationally efficient, mutual radiation impedance based approach to model a finite-size array and realistic parameters of variation. The simulations are verified, and tunability is demonstrated by experiments on a linear CMUT array operating in 2-12 MHz range.

  7. Supported silver clusters as nanoplasmonic transducers for protein sensing

    DEFF Research Database (Denmark)

    Fojan, Peter; Hanif, Muhammad; Bartling, Stephen

    2015-01-01

    Transducers for optical sensing of proteins are prepared using cluster beam deposition on quartz substrates. Surface plasmon resonance phenomenon of the supported silver clusters is used for the detection. It is shown that surface immobilisation procedure providing adhesion of the silver clusters...... stages and protein immobilisation scheme the sensing of protein of interest can be assured using a relatively simple optical spectroscopy method....... an enhancement of the plasmon absorption band used for the detection. Atomic force microscopy study allows to suggest that immobilisation of antibodies on silver clusters has been achieved, thus giving a possibility to incubate and detect an antigen of interest. Hence, by applying the developed preparation...

  8. A Treatise on Acoustic Radiation. Volume 2. Acoustic Transducers

    Science.gov (United States)

    1983-01-01

    Newton) V (meter/sec) acoustical p (Newton/meter2 ) U (meter 3/sec) To display Eq. 1.53.1 in simple form we take time to be given by exp(- iot ) and choose...if all the C-component edges and e-drivers are in the tree, all the L-component "A edges and idrivers are in the cotree, all the algebraic equations...momentum and mass of the elastic field then become, (a) Al - V -T + F 278 W-4. ,-,- * * * 4 % • *.• Design of Acoustic Transducers IOT (b) I + VV-s

  9. Immersed acoustical transducers and their potential uses in LMFBR

    International Nuclear Information System (INIS)

    Argous, J.P.; Brunet, M.; Baron, J.; Lhuillier, C.; Segui, J.L.

    1980-04-01

    Six years satisfactory operation in PHENIX has proved the reliability and effectivness of under-sodium viewing (VISUS) and Acoustic Detection. This fact has been strong incentive to maintain, on the future LMFBR the visus as well as the Acoustic Detection functions. These two functions are performed on SUPER PHENIX, by two sets of distinct systems using the well-known solution. Taking into account of recent improvements in sodium immersible acoustic transducers technology, CEA decided to undertake the development of a multi-functions instrument. This paper gives an outline of this new concept, which should be able to reduce the cost and the complexity of core instrumentation

  10. Making transducers and sensors which lead to safer mining

    Energy Technology Data Exchange (ETDEWEB)

    Laird, R

    1977-10-20

    MRDE work on transducers and sensors is described. A device containing a radioactive source has already been developed for detecting the edge of a coal seam; on a device which senses the edge of the seam by measuring natural radiation form the neighbouring rocks. Hard bands or dirt in a seam can be located by measuring pick force or pick vibrations. Environmental monitors, sensors for measuring pressure and flow in methane drainage pipes, vibration monitors for fans, means of detecting cage position in pit shaft, and bunker control systems are also mentioned.

  11. Three-dimensional micro electromechanical system piezoelectric ultrasound transducer

    Science.gov (United States)

    Hajati, Arman; Latev, Dimitre; Gardner, Deane; Hajati, Azadeh; Imai, Darren; Torrey, Marc; Schoeppler, Martin

    2012-12-01

    Here we present the design and experimental acoustic test data for an ultrasound transducer technology based on a combination of micromachined dome-shaped piezoelectric resonators arranged in a flexible architecture. Our high performance niobium-doped lead zirconate titanate film is implemented in three-dimensional dome-shaped structures, which form the basic resonating cells. Adjustable frequency response is realized by mixing these basic cells and modifying their dimensions by lithography. Improved characteristics such as high sensitivity, adjustable wide-bandwidth frequency response, low transmit voltage compatible with ordinary integrated circuitry, low electrical impedance well matched to coaxial cabling, and intrinsic acoustic impedance match to water are demonstrated.

  12. Development of a High-Temperature Smart Transducer Interface Node and Telemetry System (HSTINTS)

    Energy Technology Data Exchange (ETDEWEB)

    Buckner, M.A. et al.

    2006-11-03

    Halliburton Energy Services and Oak Ridge National Laboratory established a CRADA to conduct applied research to develop a general purpose, High-Temperature, Smart Transducer Interface Node and Telemetry System (HSTINTS) capable of temporally-coherent multiple-channel, high speed, high-resolution data transuction and acquisition while operating in a hostile thermal, chemical, and pressure environment for extended periods of time over a single coaxial cable. This ambitious, high-risk effort required development of custom dielectric isolated integrated circuits, amplified hybrid couplers for telemetry and an audio-frequency based power supply and distribution system using an engineered application of standing waves to compensate voltage drop along a 2 mile long cable. Several goals were achieved but underestimated challenges and a couple of mistakes hampered progress. When it was determined that an additional year of concerted effort would be required to complete the system demonstration, the sponsor withdrew funding and terminated the effort.

  13. Energy

    International Nuclear Information System (INIS)

    Bobin, J.L.

    1996-01-01

    Object of sciences and technologies, energy plays a major part in economics and relations between nations. Jean-Louis Bobin, physicist, analyses the relations between man and energy and wonders about fears that delivers nowadays technologies bound to nuclear energy and about the fear of a possible shortage of energy resources. (N.C.). 17 refs., 14 figs., 2 tabs

  14. Artificial Enzymes, "Chemzymes"

    DEFF Research Database (Denmark)

    Bjerre, Jeannette; Rousseau, Cyril Andre Raphaël; Pedersen, Lavinia Georgeta M

    2008-01-01

    Enzymes have fascinated scientists since their discovery and, over some decades, one aim in organic chemistry has been the creation of molecules that mimic the active sites of enzymes and promote catalysis. Nevertheless, even today, there are relatively few examples of enzyme models that successf......Enzymes have fascinated scientists since their discovery and, over some decades, one aim in organic chemistry has been the creation of molecules that mimic the active sites of enzymes and promote catalysis. Nevertheless, even today, there are relatively few examples of enzyme models...... that successfully perform Michaelis-Menten catalysis under enzymatic conditions (i.e., aqueous medium, neutral pH, ambient temperature) and for those that do, very high rate accelerations are seldomly seen. This review will provide a brief summary of the recent developments in artificial enzymes, so called...... "Chemzymes", based on cyclodextrins and other molecules. Only the chemzymes that have shown enzyme-like activity that has been quantified by different methods will be mentioned. This review will summarize the work done in the field of artificial glycosidases, oxidases, epoxidases, and esterases, as well...

  15. Magnetically responsive enzyme powders

    Energy Technology Data Exchange (ETDEWEB)

    Pospiskova, Kristyna, E-mail: kristyna.pospiskova@upol.cz [Regional Centre of Advanced Technologies and Materials, Palacky University, Slechtitelu 11, 783 71 Olomouc (Czech Republic); Safarik, Ivo, E-mail: ivosaf@yahoo.com [Regional Centre of Advanced Technologies and Materials, Palacky University, Slechtitelu 11, 783 71 Olomouc (Czech Republic); Department of Nanobiotechnology, Institute of Nanobiology and Structural Biology of GCRC, Na Sadkach 7, 370 05 Ceske Budejovice (Czech Republic)

    2015-04-15

    Powdered enzymes were transformed into their insoluble magnetic derivatives retaining their catalytic activity. Enzyme powders (e.g., trypsin and lipase) were suspended in various liquid media not allowing their solubilization (e.g., saturated ammonium sulfate and highly concentrated polyethylene glycol solutions, ethanol, methanol, 2-propanol) and subsequently cross-linked with glutaraldehyde. Magnetic modification was successfully performed at low temperature in a freezer (−20 °C) using magnetic iron oxides nano- and microparticles prepared by microwave-assisted synthesis from ferrous sulfate. Magnetized cross-linked enzyme powders were stable at least for two months in water suspension without leakage of fixed magnetic particles. Operational stability of magnetically responsive enzymes during eight repeated reaction cycles was generally without loss of enzyme activity. Separation of magnetically modified cross-linked powdered enzymes from reaction mixtures was significantly simplified due to their magnetic properties. - Highlights: • Cross-linked enzyme powders were prepared in various liquid media. • Insoluble enzymes were magnetized using iron oxides particles. • Magnetic iron oxides particles were prepared by microwave-assisted synthesis. • Magnetic modification was performed under low (freezing) temperature. • Cross-linked powdered trypsin and lipase can be used repeatedly for reaction.

  16. Targeted enzyme prodrug therapies.

    Science.gov (United States)

    Schellmann, N; Deckert, P M; Bachran, D; Fuchs, H; Bachran, C

    2010-09-01

    The cure of cancer is still a formidable challenge in medical science. Long-known modalities including surgery, chemotherapy and radiotherapy are successful in a number of cases; however, invasive, metastasized and inaccessible tumors still pose an unresolved and ongoing problem. Targeted therapies designed to locate, detect and specifically kill tumor cells have been developed in the past three decades as an alternative to treat troublesome cancers. Most of these therapies are either based on antibody-dependent cellular cytotoxicity, targeted delivery of cytotoxic drugs or tumor site-specific activation of prodrugs. The latter is a two-step procedure. In the first step, a selected enzyme is accumulated in the tumor by guiding the enzyme or its gene to the neoplastic cells. In the second step, a harmless prodrug is applied and specifically converted by this enzyme into a cytotoxic drug only at the tumor site. A number of targeting systems, enzymes and prodrugs were investigated and improved since the concept was first envisioned in 1974. This review presents a concise overview on the history and latest developments in targeted therapies for cancer treatment. We cover the relevant technologies such as antibody-directed enzyme prodrug therapy (ADEPT), gene-directed enzyme prodrug therapy (GDEPT) as well as related therapies such as clostridial- (CDEPT) and polymer-directed enzyme prodrug therapy (PDEPT) with emphasis on prodrug-converting enzymes, prodrugs and drugs.

  17. Enzymes in Fermented Fish.

    Science.gov (United States)

    Giyatmi; Irianto, H E

    Fermented fish products are very popular particularly in Southeast Asian countries. These products have unique characteristics, especially in terms of aroma, flavor, and texture developing during fermentation process. Proteolytic enzymes have a main role in hydrolyzing protein into simpler compounds. Fermentation process of fish relies both on naturally occurring enzymes (in the muscle or the intestinal tract) as well as bacteria. Fermented fish products processed using the whole fish show a different characteristic compared to those prepared from headed and gutted fish. Endogenous enzymes like trypsin, chymotrypsin, elastase, and aminopeptidase are the most involved in the fermentation process. Muscle tissue enzymes like cathepsins, peptidases, transaminases, amidases, amino acid decarboxylases, glutamic dehydrogenases, and related enzymes may also play a role in fish fermentation. Due to the decreased bacterial number during fermentation, contribution of microbial enzymes to proteolysis may be expected prior to salting of fish. Commercial enzymes are supplemented during processing for specific purposes, such as quality improvement and process acceleration. In the case of fish sauce, efforts to accelerate fermentation process and to improve product quality have been studied by addition of enzymes such as papain, bromelain, trypsin, pepsin, and chymotrypsin. © 2017 Elsevier Inc. All rights reserved.

  18. Development of a Novel Transparent Flexible Capacitive Micromachined Ultrasonic Transducer

    Directory of Open Access Journals (Sweden)

    Da-Chen Pang

    2017-06-01

    Full Text Available This paper presents the world’s first transparent flexible capacitive micromachined ultrasonic transducer (CMUT that was fabricated through a roll-lamination technique. This polymer-based CMUT has advantages of transparency, flexibility, and non-contacting detection which provide unique functions in display panel applications. Comprising an indium tin oxide-polyethylene terephthalate (ITO-PET substrate, SU-8 sidewall and vibrating membranes, and silver nanowire transparent electrode, the transducer has visible-light transmittance exceeding 80% and can operate on curved surfaces with a 40 mm radius of curvature. Unlike the traditional silicon-based high temperature process, the CMUT can be fabricated on a flexible substrate at a temperature below 100 °C to reduce residual stress introduced at high temperature. The CMUT on the curved surfaces can detect a flat target and finger at distances up to 50 mm and 40 mm, respectively. The transparent flexible CMUT provides a better human-machine interface than existing touch panels because it can be integrated with a display panel for non-contacting control in a health conscious environment and the flexible feature is critical for curved display and wearable electronics.

  19. Putting Encyclopaedia Knowledge into Structural Form: Finite State Transducers Approach

    Directory of Open Access Journals (Sweden)

    Pajić Vesna

    2011-06-01

    Full Text Available In biology and functional genomics in particular, understanding the dependence and interplay between different genome and ecological characteristics of organisms is a very challenging problem. There are some public databases which combine this kind of information, but there is still much more information about microbes and other organisms that reside in unstructured and semi-structured documents, such as encyclopaedias. In this paper we present a method for extracting information from semi-structured resources, such as encyclopaedias, based on finite state transducers, consisting of two clearly distinguished phases. The first phase strongly relies on the analysis of the document structure and it is used for locating records of data in the text. The second phase is based on the finite state transducers created for extracting the data, which can be modified so as to achieve the preferred efficiency and it is used for extracting the particular characteristic from the text. We show how the two phase method is applied to the text of the encyclopaedia “Systematic Bacteriology”. A fully structured database with genotype and phenotype characteristics of organisms has been created from the encyclopaedia unstructured descriptions.

  20. Sensitivity-Bandwidth Limit in a Multimode Optoelectromechanical Transducer

    Science.gov (United States)

    Moaddel Haghighi, I.; Malossi, N.; Natali, R.; Di Giuseppe, G.; Vitali, D.

    2018-03-01

    An optoelectromechanical system formed by a nanomembrane capacitively coupled to an L C resonator and to an optical interferometer has recently been employed for the highly sensitive optical readout of rf signals [T. Bagci et al., Nature (London) 507, 81 (2013), 10.1038/nature13029]. We propose and experimentally demonstrate how the bandwidth of such a transducer can be increased by controlling the interference between two electromechanical interaction pathways of a two-mode mechanical system. With a proof-of-principle device operating at room temperature, we achieve a sensitivity of 300 nV /√{Hz } over a bandwidth of 15 kHz in the presence of radio-frequency noise, and an optimal shot-noise-limited sensitivity of 10 nV /√{Hz } over a bandwidth of 5 kHz. We discuss strategies for improving the performance of the device, showing that, for the same given sensitivity, a mechanical multimode transducer can achieve a bandwidth significantly larger than that for a single-mode one.

  1. A ring transducer system for medical ultrasound research.

    Science.gov (United States)

    Waag, Robert C; Fedewa, Russell J

    2006-10-01

    An ultrasonic ring transducer system has been developed for experimental studies of scattering and imaging. The transducer consists of 2048 rectangular elements with a 2.5-MHz center frequency, a 67% -6 dB bandwidth, and a 0.23-mm pitch arranged in a 150-mm-diameter ring with a 25-mm elevation. At the center frequency, the element size is 0.30lambda x 42lambda and the pitch is 0.38lambda. The system has 128 parallel transmit channels, 16 parallel receive channels, a 2048:128 transmit multiplexer, a 2048:16 receive multiplexer, independently programmable transmit waveforms with 8-bit resolution, and receive amplifiers with time variable gain independently programmable over a 40-dB range. Receive signals are sampled at 20 MHz with 12-bit resolution. Arbitrary transmit and receive apertures can be synthesized. Calibration software minimizes system nonidealities caused by noncircularity of the ring and element-to-element response differences. Application software enables the system to be used by specification of high-level parameters in control files from which low-level hardware-dependent parameters are derived by specialized code. Use of the system is illustrated by producing focused and steered beams, synthesizing a spatially limited plane wave, measuring angular scattering, and forming b-scan images.

  2. Two high accuracy digital integrators for Rogowski current transducers

    Science.gov (United States)

    Luo, Pan-dian; Li, Hong-bin; Li, Zhen-hua

    2014-01-01

    The Rogowski current transducers have been widely used in AC current measurement, but their accuracy is mainly subject to the analog integrators, which have typical problems such as poor long-term stability and being susceptible to environmental conditions. The digital integrators can be another choice, but they cannot obtain a stable and accurate output for the reason that the DC component in original signal can be accumulated, which will lead to output DC drift. Unknown initial conditions can also result in integral output DC offset. This paper proposes two improved digital integrators used in Rogowski current transducers instead of traditional analog integrators for high measuring accuracy. A proportional-integral-derivative (PID) feedback controller and an attenuation coefficient have been applied in improving the Al-Alaoui integrator to change its DC response and get an ideal frequency response. For the special design in the field of digital signal processing, the improved digital integrators have better performance than analog integrators. Simulation models are built for the purpose of verification and comparison. The experiments prove that the designed integrators can achieve higher accuracy than analog integrators in steady-state response, transient-state response, and temperature changing condition.

  3. Sensitivity analysis for improving nanomechanical photonic transducers biosensors

    International Nuclear Information System (INIS)

    Fariña, D; Álvarez, M; Márquez, S; Lechuga, L M; Dominguez, C

    2015-01-01

    The achievement of high sensitivity and highly integrated transducers is one of the main challenges in the development of high-throughput biosensors. The aim of this study is to improve the final sensitivity of an opto-mechanical device to be used as a reliable biosensor. We report the analysis of the mechanical and optical properties of optical waveguide microcantilever transducers, and their dependency on device design and dimensions. The selected layout (geometry) based on two butt-coupled misaligned waveguides displays better sensitivities than an aligned one. With this configuration, we find that an optimal microcantilever thickness range between 150 nm and 400 nm would increase both microcantilever bending during the biorecognition process and increase optical sensitivity to 4.8   ×   10 −2  nm −1 , an order of magnitude higher than other similar opto-mechanical devices. Moreover, the analysis shows that a single mode behaviour of the propagating radiation is required to avoid modal interference that could misinterpret the readout signal. (paper)

  4. Phononic Crystal Waveguide Transducers for Nonlinear Elastic Wave Sensing.

    Science.gov (United States)

    Ciampa, Francesco; Mankar, Akash; Marini, Andrea

    2017-11-07

    Second harmonic generation is one of the most sensitive and reliable nonlinear elastic signatures for micro-damage assessment. However, its detection requires powerful amplification systems generating fictitious harmonics that are difficult to discern from pure nonlinear elastic effects. Current state-of-the-art nonlinear ultrasonic methods still involve impractical solutions such as cumbersome signal calibration processes and substantial modifications of the test component in order to create material-based tunable harmonic filters. Here we propose and demonstrate a valid and sensible alternative strategy involving the development of an ultrasonic phononic crystal waveguide transducer that exhibits both single and multiple frequency stop-bands filtering out fictitious second harmonic frequencies. Remarkably, such a sensing device can be easily fabricated and integrated on the surface of the test structure without altering its mechanical and geometrical properties. The design of the phononic crystal structure is supported by a perturbative theoretical model predicting the frequency band-gaps of periodic plates with sinusoidal corrugation. We find our theoretical findings in excellent agreement with experimental testing revealing that the proposed phononic crystal waveguide transducer successfully attenuates second harmonics caused by the ultrasonic equipment, thus demonstrating its wide range of potential applications for acousto/ultrasonic material damage inspection.

  5. Iron-free moving coil high temperature displacement transducer

    Energy Technology Data Exchange (ETDEWEB)

    Grindrod, A

    1976-07-01

    A unique, iron free, moving coil linear displacement transducer system is described, which is suitable for continuously monitoring linear movements, at varying temperatures up to 750/sup 0/C, in operational nuclear reactors. Although this device has been primarily developed for Advanced Gas Cooled Reactor Systems, it also has uses where long term measurements on conventional high temperature plant are required. Furthermore it could be particularly useful in material creep laboratories where precise linear changes in specimen length need to be monitored at elevated temperatures, over several years. Since individual transducer installations demand specific mounting arrangements to suit particular component geometries, evaluations have been made only on standard operational modules or capsules which are designed for containment in a range of housing or fixtures to suit particular applications. The behaviour of these devices has been studied at temperatures up to 750/sup 0/C for periods of over 10,000 h. An evaluation is also included of a commercially designed sensor assembly employing the same principle, for monitoring the boiler-shield wall movement at Hinkley Point 'B' AGR Station.

  6. Design of HIFU Transducers to Generate Specific Nonlinear Ultrasound Fields

    Science.gov (United States)

    Khokhlova, Vera A.; Yuldashev, Petr V.; Rosnitskiy, Pavel B.; Maxwell, Adam D.; Kreider, Wayne; Bailey, Michael R.; Sapozhnikov, Oleg A.

    Various clinical applications of high intensity focused ultrasound (HIFU) have different requirements on the pressure level and degree of nonlinear waveform distortion at the focus. Applications that utilize nonlinear waves with developed shocks are of growing interest, for example, for mechanical disintegration as well as for accelerated thermal ablation oftissue. In this work, an inverse problem of determining transducer parameters to enable formation of shockswith desired amplitude at the focus is solved. The solution was obtained by performing multipledirect simulations of the parabolic Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation for various parameters of the source. It is shown that results obtained within the parabolic approximation can be used to describe the focal region of single element spherical sourcesas well as complex transducer arrays. It is also demonstrated that the focal pressure level at which fully developed shocksare formed mainly depends on the focusing angle of the source and only slightly depends on its aperture and operating frequency. Using the simulation results, a 256-element HIFU array operating at 1.5 MHz frequency was designed for a specific application of boiling-histotripsy that relies on the presence of 90-100 MPa shocks at the focus. The size of the array elements and focusing angle of the array were chosen to satisfy technical limitations on the intensity at the array elements and desired shock amplitudes in the focal waveform. Focus steering capabilities of the array were analysed using an open-source T-Array software developed at Moscow State University.

  7. Raman and fluorescence microscopy sensing energy-transducing and energy-storing structures in microalgae

    Czech Academy of Sciences Publication Activity Database

    Moudříková, Š.; Mojzeš, P.; Zachleder, Vilém; Pfaff, Ch.; Behrendt, D.; Nedbal, L.

    2016-01-01

    Roč. 16, June (2016), s. 224-232 ISSN 2211-9264 Institutional support: RVO:61388971 Keywords : Biofuels * Lipids * Photosynthesis Subject RIV: EE - Microbiology, Virology Impact factor: 3.994, year: 2016

  8. Energy

    CERN Document Server

    Foland, Andrew Dean

    2007-01-01

    Energy is the central concept of physics. Unable to be created or destroyed but transformable from one form to another, energy ultimately determines what is and isn''t possible in our universe. This book gives readers an appreciation for the limits of energy and the quantities of energy in the world around them. This fascinating book explores the major forms of energy: kinetic, potential, electrical, chemical, thermal, and nuclear.

  9. High-frequency Doppler ultrasound transducer for the peripheral circulatory system

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Youngmin; Yang, Jeongwon; Kang, Uk; Kim, Guanghoon [Korea Electrotechnology Research Institute, Ansan (Korea, Republic of)

    2011-12-15

    A Doppler ultrasound transducer was designed and implemented to measure the blood flow velocity in tiny vessels near the skin of hands or feet. The geometric parameters of the transducer for defining the observation volume were derived and implemented with an acoustic window made of polystyrene. The observation volume designed in this study was located 6.5 mm from the transducer, which was comparable to the value predicted geometrically. The two-way insertion loss of the transducer was -11.3 dB on ultrasound frequency of 20 MHz, and the 3-dB bandwidth was approximately 2 MHz. In addition, the Doppler shift in the frequency measured by using a Doppler device composed of the transducer and a Doppler signal processing unit was proportional to the flow velocity generated by a homemade flowing system. Finally, we concluded that the transducer could be applied to measure the blood flow velocity in hands or feet.

  10. High-frequency Doppler ultrasound transducer for the peripheral circulatory system

    International Nuclear Information System (INIS)

    Bae, Youngmin; Yang, Jeongwon; Kang, Uk; Kim, Guanghoon

    2011-01-01

    A Doppler ultrasound transducer was designed and implemented to measure the blood flow velocity in tiny vessels near the skin of hands or feet. The geometric parameters of the transducer for defining the observation volume were derived and implemented with an acoustic window made of polystyrene. The observation volume designed in this study was located 6.5 mm from the transducer, which was comparable to the value predicted geometrically. The two-way insertion loss of the transducer was -11.3 dB on ultrasound frequency of 20 MHz, and the 3-dB bandwidth was approximately 2 MHz. In addition, the Doppler shift in the frequency measured by using a Doppler device composed of the transducer and a Doppler signal processing unit was proportional to the flow velocity generated by a homemade flowing system. Finally, we concluded that the transducer could be applied to measure the blood flow velocity in hands or feet.

  11. Class H power amplifier for power saving in fluxgate current transducers

    OpenAIRE

    Velasco Quesada, Guillermo; Román Lumbreras, Manuel; Pérez Delgado, Raul; Conesa Roca, Alfons

    2016-01-01

    This paper presents a new improvement in the design of a fluxgate-based current transducer in order to reduce the power consumption of control electronics. The proposed improvement involves the replacement of the output linear amplifier of the transducer by a class H amplifier. The output amplifier is devoted to the magnetic flux compensation and generates the transducer output current, which is proportional to the current to be measured. In this way, it is possible to reduce significantly th...

  12. Effect of planecta and ROSE? on the frequency characteristics of blood pressure-transducer kits

    OpenAIRE

    Fujiwara, Shigeki; Kawakubo, Yoshifumi; Mori, Satoshi; Tachihara, Keiichi; Toyoguchi, Izumi; Yokoyama, Takeshi

    2014-01-01

    Pressure-transducer kits have frequency characteristics such as natural frequency and damping coefficient, which affect the monitoring accuracy. The aim of the present study was to investigate the effect of planecta ports and a damping device (ROSE?, Argon Medical Devices, TX, USA) on the frequency characteristics of pressure-transducer kits. The FloTrac sensor kit (Edwards Lifesciences, CA, USA) and the DTXplus transducer kit (Argon Medical Devices) were prepared with planecta ports, and the...

  13. Local Interaction Simulation Approach for Fault Detection in Medical Ultrasonic Transducers

    Directory of Open Access Journals (Sweden)

    Z. Hashemiyan

    2015-01-01

    Full Text Available A new approach is proposed for modelling medical ultrasonic transducers operating in air. The method is based on finite elements and the local interaction simulation approach. The latter leads to significant reductions of computational costs. Transmission and reception properties of the transducer are analysed using in-air reverberation patterns. The proposed approach can help to provide earlier detection of transducer faults and their identification, reducing the risk of misdiagnosis due to poor image quality.

  14. Detection and generation of first sound in4He by vibrating superleak transducers

    Science.gov (United States)

    Giordano, N.; Edison, N.

    1986-07-01

    Measurement is made of the first-sound generation and detection efficiencies of vibrating superleak transducers (VSTs) operated in superfluid4He. This is accomplished by using an ordinary pressure transducer to generate first sound with a VST as the detector, and by using a pressure transducer to detect the sound generated by a VST. The results are in reasonably good agreement with the current theory of VST operation.

  15. Detection and generation of first sound in 4He by vibrating superleak transducers

    International Nuclear Information System (INIS)

    Giordano, N.; Edison, N.

    1986-01-01

    Measurement is made of the first-sound generation and detection efficiencies of vibrating superleak transducers (VSTs) operated in superfluid 4 He. This is accomplished by using an ordinary pressure transducer to generate first sound with a VST as the detector, and by using a pressure transducer to detect the sound generated by a VST. The results are in reasonably good agreement with the current theory of VST operation

  16. A Float Type Liquid Level Measuring System Using a Modified Inductive Transducer

    Directory of Open Access Journals (Sweden)

    Samik MARICK

    2014-11-01

    Full Text Available Float type liquid level sensor is generally used as a very simple technique for local level indication and level switching. In the present paper a technique has been proposed to transmit the measured liquid level signal of a float type sensor at remote terminal using a modified differential inductance type electromechanical transducer. The theoretical characteristic equation of this transducer has been derived. A prototype unit of the transducer has been developed and fabricated and its performance characteristic has been experimentally determined. The experimental results are reported in the paper. From experimental data, a very good linear characteristic of the proposed level transducer has been observed.

  17. A High-Voltage Class D Audio Amplifier for Dielectric Elastomer Transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2014-01-01

    Dielectric Elastomer (DE) transducers have emerged as a very interesting alternative to the traditional electrodynamic transducer. Lightweight, small size and high maneuverability are some of the key features of the DE transducer. An amplifier for the DE transducer suitable for audio applications...... is proposed and analyzed. The amplifier addresses the issue of a high impedance load, ensuring a linear response over the midrange region of the audio bandwidth (100 Hz – 3.5 kHz). THD+N below 0.1% are reported for the ± 300 V prototype amplifier producing a maximum of 125 Var at a peak efficiency of 95 %....

  18. New improvement of the combined optical fiber transducer for landslide monitoring

    Science.gov (United States)

    Zhu, Z.-W.; Yuan, Q.-Y.; Liu, D.-Y.; Liu, B.; Liu, J.-C.; Luo, H.

    2014-08-01

    Landslide monitoring is important in predicting the behavior of landslides, thereby ensuring environmental, life, and property safety. On the basis of our previous studies, we conducted the double shear test by using a third-generation optical fiber transducer that uses expandable polystyrene (EPS) as base material. However, the third-generation transducer has poor performance when cohesive force is present between the grout and capillary stainless steel pipe of the transducer. Thus, the fourth-generation optical fiber transducer was invented. Similar to the third-generation transducer, the fourth-generation transducer also used EPS as its base material. Single shear test was conducted on the fourth-generation transducer after being grouted with cement mortar (1 : 1 mix ratio). The micro-bend loss mechanism of the optical fiber was considered, and the optical time domain reflectometry instrument was used. The fact that the loss sequence of optical fibers subjected to loading is different at various locations is found. The relationship of the loading-point displacement vs. optical fiber sliding distance and optical loss were measured. Results show that the maximum initial measurement precision of the newly proposed device is 1 mm, the corresponding sliding distance is 21 mm, and the dynamic range is 0-20 mm. The fourth-generation transducer can measure the movement direction of loadings, thus making this transducer applicable for landslide monitoring.

  19. Polarization Control with Piezoelectric and LiNbO3 Transducers

    Science.gov (United States)

    Bradley, E.; Miles, E.; Loginov, B.; Vu, N.

    Several Polarization control transducers have appeared on the market, and now automated, endless polarization control systems using these transducers are becoming available. Unfortunately it is not entirely clear what benchmark performance tests a polarization control system must pass, and the polarization disturbances a system must handle are open to some debate. We present quantitative measurements of realistic polarization disturbances and two benchmark tests we have successfully used to evaluate the performance of an automated, endless polarization control system. We use these tests to compare the performance of a system using piezoelectric transducers to that of a system using LiNbO3 transducers.

  20. On-chip RF-to-optical transducer (Conference Presentation)

    Science.gov (United States)

    Simonsen, Anders; Tsaturyan, Yeghishe; Seis, Yannick; Schmid, Silvan; Schliesser, Albert; Polzik, Eugene S.

    2016-04-01

    techniques. We will furthermore present ongoing work to couple our transducer to an RF or microwave antenna, for low-noise detection of electromagnetic signals, including sensitive measurements of magnetic fields in an MRI detector. Suppression of thermomechanical noise is a key feature of electro-optomechanical transducers, and, more generally, hybrid systems involving mechanical degrees of freedom. We have shown that engineering of the phononic density of states allows improved isolation of the relevant mechanical modes from their thermal bath [2], enabling coherence times sufficient to realize quantum-coherent optomechanical coupling. This proves the potential of the employed platform for complex transducers all the way into the quantum regime. References: [1] Bagci et al, Nature 507, 81-85, (06 March 2014) [2] Tsaturyan, et al., Optics Express, Vol. 22, Issue 6, pp. 6810-6821 (2014)

  1. Determination of acoustic impedances of multi matching layers for narrowband ultrasonic airborne transducers at frequencies <2.5 MHz - Application of a genetic algorithm.

    Science.gov (United States)

    Saffar, Saber; Abdullah, Amir

    2012-01-01

    The effective ultrasonic energy radiation into the air of piezoelectric transducers requires using multilayer matching systems with accurately selected acoustic impedances and the thickness of particular layers. One major problem of ultrasonic transducers, radiating acoustic energy into air, is to find the proper acoustic impedances of one or more matching layers. This work aims at developing an original solution to the acoustic impedance mismatch between transducer and air. If the acoustic impedance defences between transducer and air be more, then finding best matching layer(s) is harder. Therefore we consider PZT (lead zirconate titanate piezo electric) transducer and air that has huge acoustic impedance deference. The vibration source energy (PZT), which is used to generate the incident wave, consumes a part of the mechanical energy and converts it to an electrical one in theoretical calculation. After calculating matching layers, we consider the energy source as layer to design a transducer. However, this part of the mechanical energy will be neglected during the mathematical work. This approximation is correct only if the transducer is open-circuit. Since the possibilities of choosing material with required acoustic impedance are limited (the counted values cannot always be realized and applied in practice) it is necessary to correct the differences between theoretical values and the possibilities of practical application of given acoustic impedances. Such a correction can be done by manipulating other parameters of matching layers (e.g. by changing their thickness). The efficiency of the energy transmission from the piezoceramic transducer through different layers with different thickness and different attenuation enabling a compensation of non-ideal real values by changing their thickness was computer analyzed (base on genetic algorithm). Firstly, three theoretical solutions were investigated. Namely, Chebyshev, Desilets and Souquet theories. However, the

  2. Structure and function of α-glucan debranching enzymes

    DEFF Research Database (Denmark)

    Møller, Marie Sofie; Henriksen, Anette; Svensson, Birte

    2016-01-01

    α-Glucan debranching enzymes hydrolyse α-1,6-linkages in starch/glycogen, thereby, playing a central role in energy metabolism in all living organisms. They belong to glycoside hydrolase families GH13 and GH57 and several of these enzymes are industrially important. Nine GH13 subfamilies include α......-glucan debranching enzymes; isoamylase and glycogen debranching enzymes (GH13_11); pullulanase type I/limit dextrinase (GH13_12–14); pullulan hydrolase (GH13_20); bifunctional glycogen debranching enzyme (GH13_25); oligo-1 and glucan-1,6-α-glucosidases (GH13_31); pullulanase type II (GH13_39); and α-amylase domains......_39 enzymes could represent a “missing link” between the strictly α-1,6-specific debranching enzymes and the enzymes with dual specificity and α-1,4-linkage preference....

  3. Parametric analysis of electromechanical and fatigue performance of total knee replacement bearing with embedded piezoelectric transducers

    Science.gov (United States)

    Safaei, Mohsen; Meneghini, R. Michael; Anton, Steven R.

    2017-09-01

    Total knee arthroplasty is a common procedure in the United States; it has been estimated that about 4 million people are currently living with primary knee replacement in this country. Despite huge improvements in material properties, implant design, and surgical techniques, some implants fail a few years after surgery. A lack of information about in vivo kinetics of the knee prevents the establishment of a correlated intra- and postoperative loading pattern in knee implants. In this study, a conceptual design of an ultra high molecular weight (UHMW) knee bearing with embedded piezoelectric transducers is proposed, which is able to measure the reaction forces from knee motion as well as harvest energy to power embedded electronics. A simplified geometry consisting of a disk of UHMW with a single embedded piezoelectric ceramic is used in this work to study the general parametric trends of an instrumented knee bearing. A combined finite element and electromechanical modeling framework is employed to investigate the fatigue behavior of the instrumented bearing and the electromechanical performance of the embedded piezoelectric. The model is validated through experimental testing and utilized for further parametric studies. Parametric studies consist of the investigation of the effects of several dimensional and piezoelectric material parameters on the durability of the bearing and electrical output of the transducers. Among all the parameters, it is shown that adding large fillet radii results in noticeable improvement in the fatigue life of the bearing. Additionally, the design is highly sensitive to the depth of piezoelectric pocket. Finally, using PZT-5H piezoceramics, higher voltage and slightly enhanced fatigue life is achieved.

  4. Energy

    CERN Document Server

    Robertson, William C

    2002-01-01

    Confounded by kinetic energy? Suspect that teaching about simple machines isn t really so simple? Exasperated by electricity? If you fear the study of energy is beyond you, this entertaining book will do more than introduce you to the topic. It will help you actually understand it. At the book s heart are easy-to-grasp explanations of energy basics work, kinetic energy, potential energy, and the transformation of energy and energy as it relates to simple machines, heat energy, temperature, and heat transfer. Irreverent author Bill Robertson suggests activities that bring the basic concepts of energy to life with common household objects. Each chapter ends with a summary and an applications section that uses practical examples such as roller coasters and home heating systems to explain energy transformations and convection cells. The final chapter brings together key concepts in an easy-to-grasp explanation of how electricity is generated. Energy is the second book in the Stop Faking It! series published by NS...

  5. Enzymic lactose hydrolysis

    Energy Technology Data Exchange (ETDEWEB)

    Miller, J J; Brand, J C

    1980-01-01

    Acid or enzymic hydrolysis can be used to hydrolyze lactose. Advantages of both are compared and details of enzymic hydrolysis using yeast or fungal enzymes given. The new scheme outlined involves recycling lactase. Because lactose and lactase react to ultrafiltration (UF) membranes differently separation is possible. Milk or milk products are ultrafiltered to separate a concentrate from a lactose-rich permeate which is treated with lactase in a reactor until hydrolysis reaches a required level. The lactase can be removed by UF as it does not permeate the membrane, and it is recycled back to the reactor. Permeate from the second UF stage may or may not be recombined with the concentrate from the first stage to produce a low lactose product (analysis of a typical low-lactose dried whole milk is given). Batch or continuous processes are explained and a batch process without enzyme recovery is discussed. (Refs. 4).

  6. Indicators: Sediment Enzymes

    Science.gov (United States)

    Sediment enzymes are proteins that are produced by microorganisms living in the sediment or soil. They are indicators of key ecosystem processes and can help determine which nutrients are affecting the biological community of a waterbody.

  7. Enzyme Vs. Extremozyme -32 ...

    Indian Academy of Sciences (India)

    Enzymes are biocatalytic protein molecules that enhance the rates of ... to physical forces (hydrogen bonds, hydrophobic 1, electrostatic and Van der ... conformation. In 1995 ... surface against 14.7% in Klenow poll (some of the hydrophobic.

  8. Dynamic hysteretic sensing model of bending-mode Galfenol transducer

    International Nuclear Information System (INIS)

    Cao, Shuying; Zheng, Jiaju; Sang, Jie; Zhang, Pengfei; Wang, Bowen; Huang, Wenmei

    2015-01-01

    A dynamic hysteretic sensing model has been developed to predict the dynamic responses of the magnetic induction, the stress, and the output voltage for a bending-mode Galfenol unimorph transducer subjected simultaneously to acceleration and bias magnetic field. This model is obtained by coupling the hysteretic Armstrong model and the structural dynamic model of the Galfenol unimorph beam. The structural dynamic model of the beam is founded based on the Euler-Bernouli beam theory, the nonlinear constitutive equations, and the Faraday law of electromagnetic induction. Comparisons between the calculated and measured results show the model can describe dynamic nonlinear voltage characteristics of the device, and can predict hysteretic behaviors between the magnetic induction and the stress. Moreover, the model can effectively analyze the effects of the bias magnetic field, the acceleration amplitude, and frequency on the root mean square voltage of the device

  9. A distributed transducer system for functional electrical stimulation

    DEFF Research Database (Denmark)

    Gudnason, Gunnar; Nielsen, Jannik Hammel; Bruun, Erik

    2001-01-01

    to be affected by the inductive link. Neural stimulators are affected to a lesser degree, but still benefit from the partitioning. As a test case, we have designed a transceiver and a sensor chip which implement this partitioning policy. The transceiver is designed to operate in the 6.78 MHz ISM band......Implanted transducers for functional electrical stimulation (FES) powered by inductive links are subject to conflicting requirements arising from low link efficiency, a low power budget and the need for protection of the weak signals against strong RF electromagnetic fields. We propose a solution...... to these problems by partitioning the RF transceiver and sensor/actuator functions onto separate integrated circuits. By amplifying measured neural signals directly at the measurements site and converting them into the digital domain before passing them to the transceiver the signal integrity is less likely...

  10. Research on recognition of ramp angle based on transducer

    Directory of Open Access Journals (Sweden)

    Wenhao GU

    2015-12-01

    Full Text Available Focusing on the recognition of ramp angle, the relationship between the signal of vehicle transducer and real ramp angle is studied. The force change of vehicle on the ramp, and the relationship between the body tilt angle and front and rear suspension scale is discussed. According to the suspension and tire deformation, error angle of the ramp angle is deduced. A mathematical model is established with Matlab/Simulink and used for simulation to generate error curve of ramp angle. The results show that the error angle increases with the increasing of the ramp angle, and the limit value can reach 6.5%, while the identification method can effectively eliminate this error, and enhance the accuracy of ramp angle recognition.

  11. Electromagnetic acoustic transducers noncontacting ultrasonic measurements using EMATS

    CERN Document Server

    Hirao, Masahiko

    2017-01-01

    This second edition provides comprehensive information on electromagnetic acoustic transducers (EMATs), from the theory and physical principles of EMATs to the construction of systems and their applications to scientific and industrial ultrasonic measurements on materials. The original version has been complemented with selected ideas on ultrasonic measurement that have emerged since the first edition was released. The book is divided into four parts: PART I offers a self-contained description of the basic elements of coupling mechanisms along with the practical designing of EMATs for various purposes. Several implementations to compensate for EMATs’ low transfer efficiency are provided, along with useful tips on how to make an EMAT. PART II describes the principle of electromagnetic acoustic resonance (EMAR), which makes the most of EMATs’ contactless nature and is the most successful amplification mechanism for precise measurements of velocity and attenuation. PART III applies EMAR to studying physical ...

  12. Smooth driving of Mössbauer electromechanical transducers

    International Nuclear Information System (INIS)

    Veiga, A.; Mayosky, M. A.; Martínez, N.; Mendoza Zélis, P.; Pasquevich, G. A.; Sánchez, F. H.

    2011-01-01

    Quality of Mössbauer spectra is strongly related to the performance of source velocity modulator. Traditional electromechanical driving techniques demand hard-edged square or triangular velocity waveforms that introduce long settling times and demand careful driver tuning. For this work, the behavior of commercial velocity transducers and drive units was studied under different working conditions. Different velocity reference waveforms in constant-acceleration, constant-velocity and programmable-velocity techniques were tested. Significant improvement in spectrometer efficiency and accuracy was achieved by replacing triangular and square hard edges with continuous smooth-shaped transitions. A criterion for best waveform selection and synchronization is presented and attainable enhancements are evaluated. In order to fully exploit this driving technique, a compact microprocessor-based architecture is proposed and a suitable data acquisition system implementation is presented. System linearity and efficiency characterization are also shown.

  13. Nonlinear ultrasonic fatigue crack detection using a single piezoelectric transducer

    Science.gov (United States)

    An, Yun-Kyu; Lee, Dong Jun

    2016-04-01

    This paper proposes a new nonlinear ultrasonic technique for fatigue crack detection using a single piezoelectric transducer (PZT). The proposed technique identifies a fatigue crack using linear (α) and nonlinear (β) parameters obtained from only a single PZT mounted on a target structure. Based on the different physical characteristics of α and β, a fatigue crack-induced feature is able to be effectively isolated from the inherent nonlinearity of a target structure and data acquisition system. The proposed technique requires much simpler test setup and less processing costs than the existing nonlinear ultrasonic techniques, but fast and powerful. To validate the proposed technique, a real fatigue crack is created in an aluminum plate, and then false positive and negative tests are carried out under varying temperature conditions. The experimental results reveal that the fatigue crack is successfully detected, and no positive false alarm is indicated.

  14. Class D audio amplifiers for high voltage capacitive transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis

    of high volume, weight, and cost. High efficient class D amplifiers are now widely available offering power densities, that their linear counterparts can not match. Unlike the technology of audio amplifiers, the loudspeaker is still based on the traditional electrodynamic transducer invented by C.W. Rice......Audio reproduction systems contains two key components, the amplifier and the loudspeaker. In the last 20 – 30 years the technology of audio amplifiers have performed a fundamental shift of paradigm. Class D audio amplifiers have replaced the linear amplifiers, suffering from the well-known issues...... with the low level of acoustical output power and complex amplifier requirements, have limited the commercial success of the technology. Horn or compression drivers are typically favoured, when high acoustic output power is required, this is however at the expense of significant distortion combined...

  15. A Pseudo-3D Model for Electromagnetic Acoustic Transducers (EMATs

    Directory of Open Access Journals (Sweden)

    Wuliang Yin

    2018-03-01

    Full Text Available Previous methods for modelling Rayleigh waves produced by a meander-line-coil electromagnetic acoustic transducer (EMAT consisted mostly of two-dimensional (2D simulations that focussed on the vertical plane of the material. This paper presents a pseudo-three-dimensional (3D model that extends the simulation space to both vertical and horizontal planes. For the vertical plane, we combines analytical and finite-difference time-domain (FDTD methods to model Rayleigh waves’ propagation within an aluminium plate and their scattering behaviours by cracks. For the horizontal surface plane, we employ an analytical method to investigate the radiation pattern of Rayleigh waves at various depths. The experimental results suggest that the models and the modelling techniques are valid.

  16. Selective generation of ultrasonic Lamb waves by electromagnetic acoustic transducers

    International Nuclear Information System (INIS)

    Li Ming-Liang; Deng Ming-Xi; Gao Guang-Jian

    2016-01-01

    In this paper, we describe a modal expansion approach for the analysis of the selective generation of ultrasonic Lamb waves by electromagnetic acoustic transducers (EMATs). With the modal expansion approach for waveguide excitation, an analytical expression of the Lamb wave’s mode expansion coefficient is deduced, which is related to the driving frequency and the geometrical parameters of the EMAT’s meander coil, and lays a theoretical foundation for exactly analyzing the selective generation of Lamb waves with EMATs. The influences of the driving frequency on the mode expansion coefficient of ultrasonic Lamb waves are analyzed when the EMAT’s geometrical parameters are given. The numerical simulations and experimental examinations show that the ultrasonic Lamb wave modes can be effectively regulated (strengthened or restrained) by choosing an appropriate driving frequency of EMAT, with the geometrical parameters given. This result provides a theoretical and experimental basis for selectively generating a single and pure Lamb wave mode with EMATs. (special topic)

  17. On-chip RF-to-optical transducer

    DEFF Research Database (Denmark)

    Simonsen, Anders; Tsaturyan, Yeghishe; Seis, Yannick

    2016-01-01

    these diverse systems, plus technologies that utilize them, and the mature toolbox of optical techniques that routinely operates at the quantum limit. In a previous work [1], we demonstrated such a bridge by realizing simultaneous coupling between an electronic LC circuit and a quantum-noise limited optical...... noise temperatures far below the actual temperature of the mechanical element. On-chip integration of the electrical, mechanical and optical elements is necessary for an implementation of the transduction scheme that is viable for commercial applications. Reliable assembly of a strongly coupled...... electromechanical device, and inclusion of an optical cavity for enhanced optical readout, are key features of the new platform. Both can be achieved with standard cleanroom fabrication techniques. We will furthermore present ongoing work to couple our transducer to an RF or microwave antenna, for low...

  18. Campylobacter jejuni transducer like proteins: Chemotaxis and beyond.

    Science.gov (United States)

    Chandrashekhar, Kshipra; Kassem, Issmat I; Rajashekara, Gireesh

    2017-07-04

    Chemotaxis, a process that mediates directional motility toward or away from chemical stimuli (chemoeffectors/ligands that can be attractants or repellents) in the environment, plays an important role in the adaptation of Campylobacter jejuni to disparate niches. The chemotaxis system consists of core signal transduction proteins and methyl-accepting-domain-containing Transducer like proteins (Tlps). Ligands binding to Tlps relay a signal to chemotaxis proteins in the cytoplasm which initiate a signal transduction cascade, culminating into a directional flagellar movement. Tlps facilitate substrate-specific chemotaxis in C. jejuni, which plays an important role in the pathogen's adaptation, pathobiology and colonization of the chicken gastrointestinal tract. However, the role of Tlps in C. jejuni's host tissue specific colonization, physiology and virulence remains not completely understood. Based on recent studies, it can be predicted that Tlps might be important targets for developing strategies to control C. jejuni via vaccines and antimicrobials.

  19. Introduction to special session on "ultrasonic transducers for harsh environments

    Science.gov (United States)

    Tittmann, B. R.; Reinhardt, B.; Daw, J.

    2018-04-01

    This work describes the results of experiments conducted as part of an instrumented lead test in-core in a nuclear reactor with the piezoelectric and magnetostrictive materials. The experiments exposed AlN, ZnO, BiT, Remendur, and Galfenol to more neutron radiation than found in the literature. The magnetostrictive sensors produce stable ultrasonic pulse-echoes throughout much of the irradiation. The BiT transducers could operate up until approximate 5 × 10^20 n/cm^2 (E>1MeV). The piezoelectric AlN operated well during the entire experiment. The results imply that now available are candidates for operation in harsh environments found in nuclear reactors and steam generator plants.

  20. Optical detection of radio waves through a nanomechanical transducer

    DEFF Research Database (Denmark)

    Bagci, T.; Simonsen, A.; Schmid, Silvan

    2014-01-01

    Low-loss transmission and sensitive recovery of weak radio-frequency and microwave signals is a ubiquitous challenge, crucial in radio astronomy, medical imaging, navigation, and classical and quantum communication. Efficient up-conversion of radio-frequency signals to an optical carrier would...... strong coupling between the voltage fluctuations in a radio-frequency resonance circuit and the membrane's displacement, which is simultaneously coupled to light reflected off its surface. The radio-frequency signals are detected as an optical phase shift with quantum-limited sensitivity....... The corresponding half-wave voltage is in the microvolt range, orders of magnitude less than that of standard optical modulators. The noise of the transducer--beyond the measured 800 pV Hz-1/2 Johnson noise of the resonant circuit--consists of the quantum noise of light and thermal fluctuations of the membrane...

  1. Dynamic hysteretic sensing model of bending-mode Galfenol transducer

    Energy Technology Data Exchange (ETDEWEB)

    Cao, Shuying, E-mail: shuying-cao@hebut.edu.cn; Zheng, Jiaju; Sang, Jie; Zhang, Pengfei; Wang, Bowen; Huang, Wenmei [Province-Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin 300130 (China)

    2015-05-07

    A dynamic hysteretic sensing model has been developed to predict the dynamic responses of the magnetic induction, the stress, and the output voltage for a bending-mode Galfenol unimorph transducer subjected simultaneously to acceleration and bias magnetic field. This model is obtained by coupling the hysteretic Armstrong model and the structural dynamic model of the Galfenol unimorph beam. The structural dynamic model of the beam is founded based on the Euler-Bernouli beam theory, the nonlinear constitutive equations, and the Faraday law of electromagnetic induction. Comparisons between the calculated and measured results show the model can describe dynamic nonlinear voltage characteristics of the device, and can predict hysteretic behaviors between the magnetic induction and the stress. Moreover, the model can effectively analyze the effects of the bias magnetic field, the acceleration amplitude, and frequency on the root mean square voltage of the device.

  2. HIFU Transducer Characterization Using a Robust Needle Hydrophone

    Science.gov (United States)

    Howard, Samuel M.; Zanelli, Claudio I.

    2007-05-01

    A robust needle hydrophone has been developed for HIFU transducer characterization and reported on earlier. After a brief review of the hydrophone design and performance, we demonstrate its use to characterize a 1.5 MHz, 10 cm diameter, F-number 1.5 spherically focused source driven to exceed an intensity of 1400 W/cm2at its focus. Quantitative characterization of this source at high powers is assisted by deconvolving the hydrophone's calibrated frequency response in order to accurately reflect the contribution of harmonics generated by nonlinear propagation in the water testing environment. Results are compared to measurements with a membrane hydrophone at 0.3% duty cycle and to theoretical calculations, using measurements of the field at the source's radiating surface as input to a numerical solution of the KZK equation.

  3. Bidirectional microwave-mechanical-optical transducer in a dilution refrigerator

    Science.gov (United States)

    Burns, Peter S.; Higginbotham, Andrew P.; Peterson, Robert W.; Urmey, Maxwell D.; Kampel, Nir S.; Menke, Timothy; Cicak, Katarina; Simmonds, Raymond. W.; Regal, Cindy A.; Lehnert, Konrad W.

    Transferring quantum states between microwave and optical networks would be a powerful resource for quantum communication and computation. Our approach is to simultaneously couple one mode of a micromechanical oscillator to a resonant microwave circuit and a high-finesse optical cavity. Building on previous work demonstrating bidirectional and efficient classical conversion at 4 K, a new microwave-to-optical transducer is operated at 0.1 K and preparations are underway to operate it in the quantum regime. To improve transfer efficiency, we characterize and implement wireless microwave access to the converter chip. Transfer efficiency of the device is measured, and loss in the LC circuit due to laser light is characterized. We acknowledge support from AFOSR MURI Grant FA9550-15-1-0015 and PFC National Science Foundation Grant 1125844.

  4. Monitoring of Grouting Compactness in a Post-Tensioning Tendon Duct Using Piezoceramic Transducers

    Directory of Open Access Journals (Sweden)

    Tianyong Jiang

    2016-08-01

    Full Text Available A post-tensioning tendon duct filled with grout can effectively prevent corrosion of the reinforcement, maintain bonding behavior between the reinforcement and concrete, and enhance the load bearing capacity of concrete structures. In practice, grouting of the post-tensioning tendon ducts always causes quality problems, which may reduce structural integrity and service life, and even cause accidents. However, monitoring of the grouting compactness is still a challenge due to the invisibility of the grout in the duct during the grouting process. This paper presents a stress wave-based active sensing approach using piezoceramic transducers to monitor the grouting compactness in real time. A segment of a commercial tendon duct was used as research object in this study. One lead zirconate titanate (PZT piezoceramic transducer with marble protection, called a smart aggregate (SA, was bonded on the tendon and installed in the tendon duct. Two PZT patch sensors were mounted on the top outside surface of the duct, and one PZT patch sensor was bonded on the bottom outside surface of the tendon duct. In the active sensing approach, the SA was used as an actuator to generate a stress wave and the PZT sensors were utilized to detect the wave response. Cement or grout in the duct functions as a wave conduit, which can propagate the stress wave. If the cement or grout is not fully filled in the tendon duct, the top PZT sensors cannot receive much stress wave energy. The experimental procedures simulated four stages during the grout pouring process, which includes empty status, half grouting, 90% grouting, and full grouting of the duct. Experimental results show that the bottom PZT sensor can detect the signal when the grout level increases towards 50%, when a conduit between the SA and PZT sensor is formed. The top PZT sensors cannot receive any signal until the grout process is completely finished. The wavelet packet-based energy analysis was adopted in this

  5. Overproduction of ligninolytic enzymes

    Science.gov (United States)

    Elisashvili, Vladimir; Kachlishvili, Eva; Torok, Tamas

    2014-06-17

    Methods, compositions, and systems for overproducing ligninolytic enzymes from the basidiomycetous fungus are described herein. As described, the method can include incubating a fungal strain of Cerrena unicolor IBB 303 in a fermentation system having growth medium which includes lignocellulosic material and then cultivating the fungal strain in the fermentation system under conditions wherein the fungus expresses the ligninolytic enzymes. In some cases, the lignocellulosic material is mandarin peel, ethanol production residue, walnut pericarp, wheat bran, wheat straw, or banana peel.

  6. Reliability and Validity Assessment of a Linear Position Transducer

    Science.gov (United States)

    Garnacho-Castaño, Manuel V.; López-Lastra, Silvia; Maté-Muñoz, José L.

    2015-01-01

    The objectives of the study were to determine the validity and reliability of peak velocity (PV), average velocity (AV), peak power (PP) and average power (AP) measurements were made using a linear position transducer. Validity was assessed by comparing measurements simultaneously obtained using the Tendo Weightlifting Analyzer Systemi and T-Force Dynamic Measurement Systemr (Ergotech, Murcia, Spain) during two resistance exercises, bench press (BP) and full back squat (BS), performed by 71 trained male subjects. For the reliability study, a further 32 men completed both lifts using the Tendo Weightlifting Analyzer Systemz in two identical testing sessions one week apart (session 1 vs. session 2). Intraclass correlation coefficients (ICCs) indicating the validity of the Tendo Weightlifting Analyzer Systemi were high, with values ranging from 0.853 to 0.989. Systematic biases and random errors were low to moderate for almost all variables, being higher in the case of PP (bias ±157.56 W; error ±131.84 W). Proportional biases were identified for almost all variables. Test-retest reliability was strong with ICCs ranging from 0.922 to 0.988. Reliability results also showed minimal systematic biases and random errors, which were only significant for PP (bias -19.19 W; error ±67.57 W). Only PV recorded in the BS showed no significant proportional bias. The Tendo Weightlifting Analyzer Systemi emerged as a reliable system for measuring movement velocity and estimating power in resistance exercises. The low biases and random errors observed here (mainly AV, AP) make this device a useful tool for monitoring resistance training. Key points This study determined the validity and reliability of peak velocity, average velocity, peak power and average power measurements made using a linear position transducer The Tendo Weight-lifting Analyzer Systemi emerged as a reliable system for measuring movement velocity and power. PMID:25729300

  7. Measurement of enzyme activity.

    Science.gov (United States)

    Harris, T K; Keshwani, M M

    2009-01-01

    To study and understand the nature of living cells, scientists have continually employed traditional biochemical techniques aimed to fractionate and characterize a designated network of macromolecular components required to carry out a particular cellular function. At the most rudimentary level, cellular functions ultimately entail rapid chemical transformations that otherwise would not occur in the physiological environment of the cell. The term enzyme is used to singularly designate a macromolecular gene product that specifically and greatly enhances the rate of a chemical transformation. Purification and characterization of individual and collective groups of enzymes has been and will remain essential toward advancement of the molecular biological sciences; and developing and utilizing enzyme reaction assays is central to this mission. First, basic kinetic principles are described for understanding chemical reaction rates and the catalytic effects of enzymes on such rates. Then, a number of methods are described for measuring enzyme-catalyzed reaction rates, which mainly differ with regard to techniques used to detect and quantify concentration changes of given reactants or products. Finally, short commentary is given toward formulation of reaction mixtures used to measure enzyme activity. Whereas a comprehensive treatment of enzymatic reaction assays is not within the scope of this chapter, the very core principles that are presented should enable new researchers to better understand the logic and utility of any given enzymatic assay that becomes of interest.

  8. The ultrasound technology for modifying enzyme activity

    Directory of Open Access Journals (Sweden)

    Meliza Lindsay Rojas

    2016-01-01

    Full Text Available Enzymes are protein complexes compounds widely studied and used due to their ability to catalyze reactions. The food processing mainly a ims the inactivation of enzymes due to various undesirable effects. However, there are many processes that can be optimized by its catalytic activity. In this context, different technologies have been applied both to inactivate or to improve the enzymes ef ficiency. The Ultrasound technology emerges as an alternative mainly applied to achieve the enzyme inactivation. On the contrary, very few investigations show the ability of this technology under certain conditions to achieve the opposite effect (i.e. increase the catalytic activity of enzymes. The objective of this study was to correlate the ultrasonic energy delivered to the sample (J/mL with the residual enzymatic activity and explain the possible mechanisms which results in the enzymatic activation/in activation complex behavior. The activity of POD in coconut water was evaluated as a model. The enzymatic activity initially increased, followed by reduction with a trend to enzyme inactivation. This complex behavior is directly related to the applied ultr asonic energy and their direct mechanical effects on the product, as well as the effect in the enzymatic infinite intermediate states and its structural conformation changes. The obtained results are useful for both academic and industrial perspectives.

  9. The ultrasound technology for modifying enzyme activity

    Directory of Open Access Journals (Sweden)

    Meliza Lindsay

    2016-06-01

    Full Text Available Enzymes are protein complexes compounds widely studied and used due to their ability to catalyze reactions. The food processing mainly aims the inactivation of enzymes due to various undesirable effects. However, there are many processes that can be optimized by its catalytic activity. In this context, different technologies have been applied both to inactivate or to improve the enzymes efficiency. The Ultrasound technology emerges as an alternative mainly applied to achieve the enzyme inactivation. On the contrary, very few investigations show the ability of this technology under certain conditions to achieve the opposite effect (i.e. increase the catalytic activity of enzymes. The objective of this study was to correlate the ultrasonic energy delivered to the sample (J/mL with the residual enzymatic activity and explain the possible mechanisms which results in the enzymatic activation/inactivation complex behavior. The activity of POD in coconut water was evaluated as a model. The enzymatic activity initially increased, followed by reduction with a trend to enzyme inactivation. This complex behavior is directly related to the applied ultrasonic energy and their direct mechanical effects on the product, as well as the effect in the enzymatic infinite intermediate states and its structural conformation changes. The obtained results are useful for both academic and industrial perspectives.

  10. A spherically-shaped PZT thin film ultrasonic transducer with an acoustic impedance gradient matching layer based on a micromachined periodically structured flexible substrate.

    Science.gov (United States)

    Feng, Guo-Hua; Liu, Wei-Fan

    2013-10-09

    This paper presents the microfabrication of an acoustic impedance gradient matching layer on a spherically-shaped piezoelectric ultrasonic transducer. The acoustic matching layer can be designed to achieve higher acoustic energy transmission and operating bandwidth. Also included in this paper are a theoretical analysis of the device design and a micromachining technique to produce the novel transducer. Based on a design of a lead titanium zirconium (PZT) micropillar array, the constructed gradient acoustic matching layer has much better acoustic transmission efficiency within a 20-50 MHz operation range compared to a matching layer with a conventional quarter-wavelength thickness Parylene deposition. To construct the transducer, periodic microcavities are built on a flexible copper sheet, and then the sheet forms a designed curvature with a ball shaping. After PZT slurry deposition, the constructed PZT micropillar array is released onto a curved thin PZT layer. Following Parylene conformal coating on the processed PZT micropillars, the PZT micropillars and the surrounding Parylene comprise a matching layer with gradient acoustic impedance. By using the proposed technique, the fabricated transducer achieves a center frequency of 26 MHz and a -6 dB bandwidth of approximately 65%.

  11. Recent Advances in the Development and Application of Power Plate Transducers in Dense Gas Extraction and Aerosol Agglomeration Processes

    Science.gov (United States)

    Riera, E.; Cardoni, A.; Gallego-Juárez, J. A.; Acosta, V. M.; Blanco, A.; Rodríguez, G.; Blasco, M.; Herranz, L. E.

    Power ultrasound (PU) is an emerging, innovative, energy saving and environmental friendly technology that is generating a great interest in sectors such as food and pharmaceutical industries, green chemistry, environmental pollution, and other processes, where sustainable and energy efficient methods are required to improve and/or produce specific effects. Two typical effects of PU are the enhancement of mass transfer in gases and liquids, and the induction of particle agglomeration in aerosols. These effects are activated by a variety of mechanisms associated to the nonlinear propagation of high amplitude ultrasonic waves such as diffusion, agitation, entrainment, turbulence, etc. During the last years a great effort has been jointly made by the Spanish National Research Council (CSIC) and the company Pusonics towards introducing novel processes into the market based on airborne ultrasonic plate transducers. This technology was specifically developed for the treatment of gas and multiphasic media characterized by low specific acoustic impedance and high acoustic absorption. Different strategies have been developed to mitigate the effects of the nonlinear dynamic behavior of such ultrasonic piezoelectric transducers in order to enhance and stabilize their response at operational power conditions. This work deals with the latter advances in the mitigation of nonlinear problems found in power transducers; besides it describes two applications assisted by ultrasound developed at semi-industrial and laboratory scales and consisting in extraction via dense gases and particle agglomeration. Dense Gas Extraction (DGE) assisted by PU is a new process with a potential to enhance the extraction kinetics with supercritical CO2. Acoustic agglomeration of fine aerosol particles has a great potential for the treatment of air pollution problems generated by particulate materials. Experimental and numerical results in both processes will be shown and discussed.

  12. Energy

    International Nuclear Information System (INIS)

    1975-10-01

    On the occasion of the World Environment Day the Norwegian Ministry for the Environment held a conference on growth problems in energy consumption. The themes which were treated were energy conservation, hydroelectric power, the role of nuclear power, radioactive waste disposal, fossil fuel resources, ecological limits, pollution and international aspects. Nuclear energy forms the main theme of one lecture and an aspect of several others. (JIW)

  13. Energy

    OpenAIRE

    Torriti, Jacopo

    2016-01-01

    The impact of energy policy measures has been assessed with various appraisal and evaluation tools since the 1960s. Decision analysis, environmental impact assessment and strategic environmental assessment are all notable examples of progenitors of Regulatory Impact Assessment (RIA) in the assessment of energy policies, programmes and projects. This chapter provides overview of policy tools which have been historically applied to assess the impacts of energy policies, programmes and projects....

  14. A Dual-Range Strain Gage Weighing Transducer Employing Automatic Switching

    Science.gov (United States)

    Rodger A. Arola

    1968-01-01

    Describes a dual-range strain gage transducer which has proven to be an excellent weight-sensing device for weighing trees and tree-length logs; discusses basic principals of the design and operation; and shows that a single transducer having two sensitivity ranges with automatic internal switching can sense weight with good repeatability and that one calibration curve...

  15. Performance limitations of piezoelectric and force feedback electrostatic transducers in different applications

    International Nuclear Information System (INIS)

    Hadjiloucas, S; Walker, G C; Bowen, J W; Karatzas, L S

    2009-01-01

    Current limitations in piezoelectric and electrostatic transducers are discussed. A force-feedback electrostatic transducer capable of operating at bandwidths up to 20 kHz is described. Advantages of the proposed design are a linearised operation which simplifies the feedback control aspects and robustness of the performance characteristics to environmental perturbations. Applications in nanotechnology, optical sciences and acoustics are discussed.

  16. Study on the sandwich piezoelectric ceramic ultrasonic transducer in thickness vibration

    International Nuclear Information System (INIS)

    Lin Shuyu; Tian Hua

    2008-01-01

    A sandwich piezoelectric ceramic ultrasonic transducer in thickness vibration is studied. The transducer consists of front and back metal masses, and coaxially segmented, thickness polarized piezoelectric ceramic thin rings. For this kind of sandwich piezoelectric transducers in thickness vibration, it is required that the lateral dimension of the transducer is sufficiently large compared with its longitudinal dimension so that no lateral displacements in the transducer can occur (laterally clamped). In this paper, the thickness vibration of the piezoelectric ceramic stack consisting of a number of identical piezoelectric ceramic thin rings is analysed and its electro-mechanical equivalent circuit is obtained. The resonance frequency equation for the sandwich piezoelectric ceramic ultrasonic transducer in thickness vibration is derived. Based on the frequency equation, two sandwich piezoelectric ceramic ultrasonic transducers are designed and manufactured, and their resonance frequencies are measured. It is shown that the measured resonance frequencies are in good agreement with the theoretical results. This kind of sandwich piezoelectric ultrasonic transducer is expected to be used in megasonic ultrasonic cleaning and sonochemistry where high power and high frequency ultrasound is needed

  17. Performance limitations of piezoelectric and force feedback electrostatic transducers in different applications

    Energy Technology Data Exchange (ETDEWEB)

    Hadjiloucas, S; Walker, G C; Bowen, J W [Cybernetics, School of Systems Engineering, University of Reading, RG6 6AY (United Kingdom); Karatzas, L S, E-mail: s.hadjiloucas@reading.ac.u [Temasek Polytechnic, School of Engineering, 21 Tampines Avenue 1, Singapore, 529757 (Singapore)

    2009-07-01

    Current limitations in piezoelectric and electrostatic transducers are discussed. A force-feedback electrostatic transducer capable of operating at bandwidths up to 20 kHz is described. Advantages of the proposed design are a linearised operation which simplifies the feedback control aspects and robustness of the performance characteristics to environmental perturbations. Applications in nanotechnology, optical sciences and acoustics are discussed.

  18. Energies

    International Nuclear Information System (INIS)

    2003-01-01

    In the framework of the National Debate on the energies in a context of a sustainable development some associations for the environment organized a debate on the nuclear interest facing the renewable energies. The first part presents the nuclear energy as a possible solution to fight against the greenhouse effect and the associated problem of the wastes management. The second part gives information on the solar energy and the possibilities of heat and electric power production. A presentation of the FEE (French wind power association) on the situation and the development of the wind power in France, is also provided. (A.L.B.)

  19. A Doubly-Curved Piezoelectric Composite with 1-3 Connectivity for Underwater Transducer Applications

    Science.gov (United States)

    Zhang, Yanjun; Wang, Likun; Qin, Lei; Liao, Qingwei; Zhong, Chao

    2018-03-01

    Aim to increase the horizontal and vertical beam width of the high frequency transducer simultaneously, we present a doubly-curved 1-3 piezoelectric composite element. It consists of 54% piezoelectric ceramic volume fraction and two phases polymer matrix. The finite element analysis (FEA) is used to evaluate the dynamic response of composite. Electroacoustic response in water was measured for the doubly-curved composite being considered as underwater transducer. An underwater transducer was fabricated using the doubly-curved 1-3 piezoelectric composite element. The -3 dB full angle beam width of transducer is approximately 106° and 36° in the horizontal and vertical plane respectively. Both the FEA simulations and experimental results show the potential of a broad covered area of the composite transducer in underwater environment.

  20. Development of a Modular Magnetostrictive Transducer for Torsional Guided Wave Transduction in a Cylindrical Structure

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Seung Hyun; Park, Jae Ha; Kwon, Hyu Sang; Ahn, Bong Young; Lee, Seung Seok [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2009-10-15

    Cylindrical structures such as pipes and shafts are widely used in various industrial facilities. Recently, researches on magnetostrictive transduction of torsional waves have been actively reported for the nondestructive evaluation of those cylindrical structures. However, the existing magnetostrictive patch transducer has somewhat inconvenient and time. Consuming process like patch bonding to a structure since it should employ a magnetostrictive patch having strong magnetostriction. To overcome these limitations of the existing transducer, in this work, we develop a novel modular magnetostrictive transducer to generate and measure torsional waves to inspect a cylindrical structure. The proposed transducer can be applied as viscous liquid coupling with shear couplant or dry coupling without coupling media instead of patch bonding to a structure. We describe a detailed structure of the modular transducer and conduct some experiments to verify its performance

  1. Development of a Modular Magnetostrictive Transducer for Torsional Guided Wave Transduction in a Cylindrical Structure

    International Nuclear Information System (INIS)

    Cho, Seung Hyun; Park, Jae Ha; Kwon, Hyu Sang; Ahn, Bong Young; Lee, Seung Seok

    2009-01-01

    Cylindrical structures such as pipes and shafts are widely used in various industrial facilities. Recently, researches on magnetostrictive transduction of torsional waves have been actively reported for the nondestructive evaluation of those cylindrical structures. However, the existing magnetostrictive patch transducer has somewhat inconvenient and time. Consuming process like patch bonding to a structure since it should employ a magnetostrictive patch having strong magnetostriction. To overcome these limitations of the existing transducer, in this work, we develop a novel modular magnetostrictive transducer to generate and measure torsional waves to inspect a cylindrical structure. The proposed transducer can be applied as viscous liquid coupling with shear couplant or dry coupling without coupling media instead of patch bonding to a structure. We describe a detailed structure of the modular transducer and conduct some experiments to verify its performance

  2. Dissimilar trend of nonlinearity in ultrasound transducers and systems at resonance and non-resonance frequencies

    DEFF Research Database (Denmark)

    Ghasemi, Negareh; Zare, Firuz; Davari, Pooya

    2017-01-01

    Several factors can affect performance of an ultrasound system such as quality of excitation signal and ultrasound transducer behaviour. Nonlinearity of piezoelectric ultrasound transducers is a key determinant in designing a proper driving power supply. Although, the nonlinearity of piezoelectric...... was excited at different frequencies. Different excitation signals were generated using a linear power amplifier and a multilevel converter within a range of 30–200 V. Empirical relation was developed to express the resistance of the piezoelectric transducer as a nonlinear function of both excitation voltage...... and resonance frequency. The impedance measurements revealed that at higher voltage ranges, the piezoelectric transducer can be easily saturated. Also, it was shown that for the developed ultrasound system composed of two transducers (one transmitter and one receiver), the output voltage measured across...

  3. Ultrasonic Transducer Design for the Axial Flaw Detection of Dissimilar Metal Weld

    International Nuclear Information System (INIS)

    Yoon, Byung Sik; Kim, Yong Sik; Yang, Seung Han

    2011-01-01

    Dissimilar metal welds in nuclear power plant are known as very susceptible to PWSCC flaws, and periodically inspected by the qualified inspector and qualified procedure during in-service inspection period. According to field survey data, the majority of their DMWs are located on tapered nozzle or adjacent to a tapered component. These types of configurations restrict examination access and also limit examination volume coverage. Additionally, circumferential scan for axially oriented flaw is very difficult to detect located on tapered surface because the transducer can't receive flaw response from reflector for miss-orientation. To overcome this miss-orientation, it is necessary adapt skewed ultrasonic transducer accommodate tapered surface. The skewed refracted longitudinal ultrasonic transducer designed by modeling and manufactured from the modelling result for axial flaw detection. Experimental results showed that the skewed refracted longitudinal ultrasonic transducer get higher flaw response than non-skewed refracted longitudinal ultrasonic transducer

  4. Metrological analysis of a virtual flowmeter-based transducer for cryogenic helium

    Energy Technology Data Exchange (ETDEWEB)

    Arpaia, P., E-mail: pasquale.arpaia@unina.it [Department of Electrical Engineering and Information Technology, University of Napoli Federico II, Naples (Italy); Technology Department, European Organization for Nuclear Research (CERN), Geneva (Switzerland); Girone, M., E-mail: mario.girone@cern.ch [Technology Department, European Organization for Nuclear Research (CERN), Geneva (Switzerland); Department of Engineering, University of Sannio, Benevento (Italy); Liccardo, A., E-mail: annalisa.liccardo@unina.it [Department of Electrical Engineering and Information Technology, University of Napoli Federico II, Naples (Italy); Pezzetti, M., E-mail: marco.pezzetti@cern.ch [Technology Department, European Organization for Nuclear Research (CERN), Geneva (Switzerland); Piccinelli, F., E-mail: fabio.piccinelli@cern.ch [Department of Mechanical Engineering, University of Brescia, Brescia (Italy)

    2015-12-15

    The metrological performance of a virtual flowmeter-based transducer for monitoring helium under cryogenic conditions is assessed. At this aim, an uncertainty model of the transducer, mainly based on a valve model, exploiting finite-element approach, and a virtual flowmeter model, based on the Sereg-Schlumberger method, are presented. The models are validated experimentally on a case study for helium monitoring in cryogenic systems at the European Organization for Nuclear Research (CERN). The impact of uncertainty sources on the transducer metrological performance is assessed by a sensitivity analysis, based on statistical experiment design and analysis of variance. In this way, the uncertainty sources most influencing metrological performance of the transducer are singled out over the input range as a whole, at varying operating and setting conditions. This analysis turns out to be important for CERN cryogenics operation because the metrological design of the transducer is validated, and its components and working conditions with critical specifications for future improvements are identified.

  5. Random-walk enzymes

    Science.gov (United States)

    Mak, Chi H.; Pham, Phuong; Afif, Samir A.; Goodman, Myron F.

    2015-09-01

    Enzymes that rely on random walk to search for substrate targets in a heterogeneously dispersed medium can leave behind complex spatial profiles of their catalyzed conversions. The catalytic signatures of these random-walk enzymes are the result of two coupled stochastic processes: scanning and catalysis. Here we develop analytical models to understand the conversion profiles produced by these enzymes, comparing an intrusive model, in which scanning and catalysis are tightly coupled, against a loosely coupled passive model. Diagrammatic theory and path-integral solutions of these models revealed clearly distinct predictions. Comparison to experimental data from catalyzed deaminations deposited on single-stranded DNA by the enzyme activation-induced deoxycytidine deaminase (AID) demonstrates that catalysis and diffusion are strongly intertwined, where the chemical conversions give rise to new stochastic trajectories that were absent if the substrate DNA was homogeneous. The C →U deamination profiles in both analytical predictions and experiments exhibit a strong contextual dependence, where the conversion rate of each target site is strongly contingent on the identities of other surrounding targets, with the intrusive model showing an excellent fit to the data. These methods can be applied to deduce sequence-dependent catalytic signatures of other DNA modification enzymes, with potential applications to cancer, gene regulation, and epigenetics.

  6. Calculation of acoustic field based on laser-measured vibration velocities on ultrasonic transducer surface

    Science.gov (United States)

    Hu, Liang; Zhao, Nannan; Gao, Zhijian; Mao, Kai; Chen, Wenyu; Fu, Xin

    2018-05-01

    Determination of the distribution of a generated acoustic field is valuable for studying ultrasonic transducers, including providing the guidance for transducer design and the basis for analyzing their performance, etc. A method calculating the acoustic field based on laser-measured vibration velocities on the ultrasonic transducer surface is proposed in this paper. Without knowing the inner structure of the transducer, the acoustic field outside it can be calculated by solving the governing partial differential equation (PDE) of the field based on the specified boundary conditions (BCs). In our study, the BC on the transducer surface, i.e. the distribution of the vibration velocity on the surface, is accurately determined by laser scanning measurement of discrete points and follows a data fitting computation. In addition, to ensure the calculation accuracy for the whole field even in an inhomogeneous medium, a finite element method is used to solve the governing PDE based on the mixed BCs, including the discretely measured velocity data and other specified BCs. The method is firstly validated on numerical piezoelectric transducer models. The acoustic pressure distributions generated by a transducer operating in an homogeneous and inhomogeneous medium, respectively, are both calculated by the proposed method and compared with the results from other existing methods. Then, the method is further experimentally validated with two actual ultrasonic transducers used for flow measurement in our lab. The amplitude change of the output voltage signal from the receiver transducer due to changing the relative position of the two transducers is calculated by the proposed method and compared with the experimental data. This method can also provide the basis for complex multi-physical coupling computations where the effect of the acoustic field should be taken into account.

  7. Bendable Electro-Acoustic Transducer Fabricated Utilizing Frequency Dispersion of Elastic Modulus

    Science.gov (United States)

    Miyoshi, Tetsu; Ohga, Juro

    2013-09-01

    To realize the speaker diaphragm that can be united with a flexible display without deteriorating lightweight properties and flexibility, a novel bendable electro-acoustic transducer (BEAT) based on 0-3-type piezoelectric composites has been developed. To overcome the trade-off between flexibility and the transmission efficiency of vibration energy, a viscoelastic polymer that has local maximum points in the loss factor as well as large frequency dispersion in the storage modulus near room temperature was employed as the matrix of the piezoelectric composite layer. Against the comparatively slow (10 Hz or less) deformation from the outside, the viscoelastic matrix is viscous enough to prevent cracking and delamination. On the other hand, in the audible range (20 Hz to 20 kHz), the matrix is elastic enough to transmit piezoelectric vibration energy, maintaining a moderately large loss factor as well as a high sound velocity. For the first time, we successfully demonstrated a rollable speaker that can continue to generate a high-quality sound while being rolled and unrolled repeatedly onto a cylinder with a curvature radius of 4 mm.

  8. Study the Possibility of Using an Elastomeric Blend as a Plastic Interfacial media in Ultrasonic Transducers

    Directory of Open Access Journals (Sweden)

    Auda Jabbar Braihi

    2017-03-01

    Full Text Available This work tries to study the using of bromobutyle / butyle elasomeric blends in ultrasonic transducers as a dry plastic interfacial media to inspect porous materials such as concrete and refractory materials which can absorb liquid medias , through the study of acoustic impedance characteristics at interfaces . These characteristics include acoustic impedance , the percentage of energy reflected, dB loss, Power ratios expressions , and Pressure ratios expressions (Reflection Coefficient & Transmission Coefficient . They are studied by using ultrasonic instrument named CSI (type CCT- 4 with 26 KHz frequency . Also, this research try to specify the suitable bromobutyle / butyle blend for immersion inspect through the matching between the acoustic impedance of the blend and that of water. Samples preparation achieved in Babylon Tiers Factory. Results showed that by increasing bromobutyle ratio in the blend both reflection coefficient and the percentage of energy reflected increased while acoustic impedance and Transmission Coefficient have been decreased. Also, the results show that 20 bromobutyle / 80 butyle is the suitable blend for immersion tests.

  9. Matrix Metalloproteinase Enzyme Family

    Directory of Open Access Journals (Sweden)

    Ozlem Goruroglu Ozturk

    2013-04-01

    Full Text Available Matrix metalloproteinases play an important role in many biological processes such as embriogenesis, tissue remodeling, wound healing, and angiogenesis, and in some pathological conditions such as atherosclerosis, arthritis and cancer. Currently, 24 genes have been identified in humans that encode different groups of matrix metalloproteinase enzymes. This review discuss the members of the matrix metalloproteinase family and their substrate specificity, structure, function and the regulation of their enzyme activity by tissue inhibitors. [Archives Medical Review Journal 2013; 22(2.000: 209-220

  10. Transition state theory for enzyme kinetics

    Science.gov (United States)

    Truhlar, Donald G.

    2015-01-01

    This article is an essay that discusses the concepts underlying the application of modern transition state theory to reactions in enzymes. Issues covered include the potential of mean force, the quantization of vibrations, the free energy of activation, and transmission coefficients to account for nonequilibrium effect, recrossing, and tunneling. PMID:26008760

  11. Nanostructured progesterone immunosensor using a tyrosinase-colloidal gold-graphite-Teflon biosensor as amperometric transducer

    Energy Technology Data Exchange (ETDEWEB)

    Carralero, Veronica [Department of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid (Spain); Gonzalez-Cortes, Araceli [Department of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid (Spain); Yanez-Sedeno, Paloma [Department of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid (Spain)]. E-mail: yseo@quim.ucm.es; Pingarron, Jose M. [Department of Analytical Chemistry, Faculty of Chemistry, University Complutense of Madrid, 28040 Madrid (Spain)

    2007-07-16

    A novel progesterone immunosensor using a colloidal gold-graphite-Teflon-tyrosinase composite biosensor as amperometric transducer is reported. A sequential competitive configuration between the analyte and progesterone labelled with alkaline phosphatase (AP) was used. Phenyl phosphate was employed as the AP-substrate and the enzyme reaction product, phenol, was oxidized by tyrosinase to o-quinone, which is subsequently reduced at -0.1 V at the biocomposite electrode. Variables such as the concentration of phenyl phosphate, the amount of antibody attached to the electrode surface, immersion time in a 2% BSA solution, working pH and incubation times in progesterone and AP conjugate were optimized. A linear calibration graph for progesterone was obtained between 0 and 40 ng mL{sup -1} with a slope value of -82.3 nA ng{sup -1} mL, and a detection limit of 0.43 ng mL{sup -1}. The time needed to reach the steady-state current from the addition of phenyl phosphate was 30-40 s. These analytical characteristics improve substantially those reported for other progesterone immunosensors. A lifetime of 14 days with no need to apply any regeneration procedure was also achieved. The usefulness of the immunosensor was evaluated by determining progesterone in milk samples spiked with the analyte at 5.0 and 1.5 ng mL{sup -1} concentration levels. Following a very simple procedure, involving only sample dilution, mean recoveries (n = 7) of 98 {+-} 3% and 99 {+-} 3%, respectively, were obtained.

  12. Glucose biosensor based on disposable electrochemical paper-based transducers fully fabricated by screen-printing.

    Science.gov (United States)

    Lamas-Ardisana, P J; Martínez-Paredes, G; Añorga, L; Grande, H J

    2018-06-30

    This paper describes a new approach for the massive production of electrochemical paper-based analytical devices (ePADs). These devices are fully fabricated by screen-printing technology and consist of a lineal microfluidic channel delimited by hydrophobic walls (patterned with diluted ultraviolet screen-printing ink in chromatographic paper grade 4) and a three-electrode system (printed with carbon and/or Ag/AgCl conductive inks). The printing process was characterised and optimized for pattern each layer with only one squeeze sweep. These ePADs were used as transducers to develop a glucose biosensor. Ionic strength/pH buffering salts, electrochemical mediator (ferricyanide) and enzyme (glucose dehydrogenase FAD-dependent) were separately stored along the microfluidic channel in order to be successively dissolved and mixed after the sample dropping at the entrance. The analyses required only 10 µl and the biosensors showed good reproducibility (RSD = 6.2%, n = 10) and sensitivity (0.426 C/M cm 2 ), wide linear range (0.5-50 mM; r 2 = 0.999) and low limit of detection (0.33 mM). Furthermore, the new biosensor was applied for glucose determination in five commercial soft-drinks without any sample treatment before the analysis. These samples were also analysed with a commercial enzymatic-kit assay. The results indicated that both methods provide accurate results. Copyright © 2018 Elsevier B.V. All rights reserved.

  13. Nanostructured progesterone immunosensor using a tyrosinase-colloidal gold-graphite-Teflon biosensor as amperometric transducer

    International Nuclear Information System (INIS)

    Carralero, Veronica; Gonzalez-Cortes, Araceli; Yanez-Sedeno, Paloma; Pingarron, Jose M.

    2007-01-01

    A novel progesterone immunosensor using a colloidal gold-graphite-Teflon-tyrosinase composite biosensor as amperometric transducer is reported. A sequential competitive configuration between the analyte and progesterone labelled with alkaline phosphatase (AP) was used. Phenyl phosphate was employed as the AP-substrate and the enzyme reaction product, phenol, was oxidized by tyrosinase to o-quinone, which is subsequently reduced at -0.1 V at the biocomposite electrode. Variables such as the concentration of phenyl phosphate, the amount of antibody attached to the electrode surface, immersion time in a 2% BSA solution, working pH and incubation times in progesterone and AP conjugate were optimized. A linear calibration graph for progesterone was obtained between 0 and 40 ng mL -1 with a slope value of -82.3 nA ng -1 mL, and a detection limit of 0.43 ng mL -1 . The time needed to reach the steady-state current from the addition of phenyl phosphate was 30-40 s. These analytical characteristics improve substantially those reported for other progesterone immunosensors. A lifetime of 14 days with no need to apply any regeneration procedure was also achieved. The usefulness of the immunosensor was evaluated by determining progesterone in milk samples spiked with the analyte at 5.0 and 1.5 ng mL -1 concentration levels. Following a very simple procedure, involving only sample dilution, mean recoveries (n = 7) of 98 ± 3% and 99 ± 3%, respectively, were obtained

  14. Simulation study of a chaotic cavity transducer based virtual phased array used for focusing in the bulk of a solid material.

    Science.gov (United States)

    Delrue, Steven; Van Den Abeele, Koen; Bou Matar, Olivier

    2016-04-01

    In acoustic and ultrasonic non-destructive testing techniques, it is sometimes beneficial to concentrate sound energy at a chosen location in space and at a specific instance in time, for example to improve the signal-to-noise ratio or activate the nonlinearity of damage features. Time Reversal (TR) techniques, taking advantage of the reversible character of the wave equation, are particularly suited to focus ultrasonic waves in time and space. The characteristics of the energy focusing in solid media using principles of time reversed acoustics are highly influenced by the nature and dimensions of the medium, the number of transducers and the length of the received signals. Usually, a large number of transducers enclosing the domain of interest is needed to improve the quality of the focusing. However, in the case of highly reverberant media, the number of transducers can be reduced to only one (single-channel TR). For focusing in a non-reverberant medium, which is impossible when using only one source, an adaptation of the single-channel reciprocal TR procedure has been recently suggested by means of a Chaotic Cavity Transducer (CCT), a single element transducer glued on a cavity of chaotic shape. In this paper, a CCT is used to focus elastic energy, at different times, in different points along a predefined line on the upper surface of a thick solid sample. Doing so, all focusing points can act as a virtual phased array transducer, allowing to focus in any point along the depth direction of the sample. This is impossible using conventional reciprocal TR, as you need to have access to all points in the bulk of the material for detecting signals to be used in the TR process. To asses and provide a better understanding of this concept, a numerical study has been developed, allowing to verify the basic concepts of the virtual phased array and to illustrate multi-component time reversal focusing in the bulk of a solid material. Copyright © 2016 Elsevier B.V. All

  15. Health Monitoring of Bolted Spherical Joint Connection Based on Active Sensing Technique Using Piezoceramic Transducers

    Directory of Open Access Journals (Sweden)

    Jing Xu

    2018-05-01

    Full Text Available Bolted spherical joints are widely used to form space steel structures. The stiffness and load capacity of the structures are affected by the looseness of bolted spherical joint connections in the structures. The looseness of the connections, which can be caused by fabrication error, low modeling accuracy, and “false twist” in the installation process, may negatively impact the load capacity of the structure and even lead to severe accidents. Furthermore, it is difficult to detect bolted spherical joint connection looseness from the outside since the bolts connect spheres with rods together from the inside. Active sensing methods are proposed in this paper to monitor the tightness status of the bolted spherical connection using piezoceramic transducers. A triangle-on-triangle offset grid composed of bolted spherical joints and steel tube bars was fabricated as the specimen and was used to validate the active sensing methods. Lead Zirconate Titanate (PZT patches were used as sensors and actuators to monitor the bolted spherical joint tightness status. One PZT patch mounted on the central bolted sphere at the upper chord was used as an actuator to generate a stress wave. Another PZT patch mounted on the bar was used as a sensor to detect the propagated waves through the bolted spherical connection. The looseness of the connection can impact the energy of the stress wave propagated through the connection. The wavelet packet analysis and time reversal (TR method were used to quantify the energy of the transmitted signal between the PZT patches by which the tightness status of the connection can be detected. In order to verify the effectiveness, repeatability, and consistency of the proposed methods, the experiments were repeated six times in different bolted spherical connection positions. The experimental results showed that the wavelet packet analysis and TR method are effective in detecting the tightness status of the connections. The

  16. The surface science of enzymes

    DEFF Research Database (Denmark)

    Rod, Thomas Holm; Nørskov, Jens Kehlet

    2002-01-01

    One of the largest challenges to science in the coming years is to find the relation between enzyme structure and function. Can we predict which reactions an enzyme catalyzes from knowledge of its structure-or from its amino acid sequence? Can we use that knowledge to modify enzyme function......? To solve these problems we must understand in some detail how enzymes interact with reactants from its surroundings. These interactions take place at the surface of the enzyme and the question of enzyme function can be viewed as the surface science of enzymes. In this article we discuss how to describe...... catalysis by enzymes, and in particular the analogies between enzyme catalyzed reactions and surface catalyzed reactions. We do this by discussing two concrete examples of reactions catalyzed both in nature (by enzymes) and in industrial reactors (by inorganic materials), and show that although analogies...

  17. Improvement of amperometric transducer selectivity using nanosized phenylenediamine films

    Science.gov (United States)

    Soldatkina, O. V.; Kucherenko, I. S.; Pyeshkova, V. M.; Alekseev, S. A.; Soldatkin, O. O.; Dzyadevych, S. V.

    2017-11-01

    In this work, we studied the conditions of deposition of a semipermeable polyphenylenediamine (PPD)-based membrane on amperometric disk platinum electrodes. Restricting an access of interfering substances to the electrode surface, the membrane prevents their impact on the sensor operation. Two methods of membrane deposition by electropolymerization were compared—at varying potential (cyclic voltammetry) and at constant potential. The cyclic voltammetry was shown to be easier in performing and providing better properties of the membrane. The dependence of PPD membrane effectiveness on the number of cyclic voltammograms and phenylenediamine concentration was analyzed. It was shown that the impact of interfering substances (ascorbic acid, dopamine, cysteine, uric acid) on sensor operation could be completely avoided using three cyclic voltammograms in 30 mM phenylenediamine. On the other hand, when working with diluted samples, i.e., at lower concentrations of electroactive substances, it is reasonable to decrease the phenylenediamine concentration to 5 mM, which would result in a higher sensitivity of transducers to hydrogen peroxide due to a thinner PPD layer. The PPD membrane was tested during continuous operation and at 8-day storage and turned out to be efficient in sensor and biosensors.

  18. Development of inter digital transducers to the control structures

    International Nuclear Information System (INIS)

    Takpara, R.; Fall, D.; Duquennoy, M.; Ouaftouh, M.; Courtois, C.; Rguiti, M.; Gonon, M.; Maurye, N.; Martic, G.; Lardot, V.; Seronveaux, L.; Halleux, J.; Pelegris, C.; Guessasma, M.

    2015-01-01

    This work deals with the realization of interdigital transducers (IDT) in order to characterize the quality of coatings and surfaces of structures. The challenge of this study is three fold. Firstly, the aim is to have efficient sensors to generate surface acoustic wave (SAW) since these wave sare well suited for this type of characterization. The second objective ofthis study is to provide flexible sensors so that they can adapt to different shapes of structures. Finally, relatively inexpensive technologies are favored for the development of these sensors because this allows continuous monitoring (structural health monitoring) by incorporating these sensors permanently on the structures to be tested. To meet these goals, several French and Belgian laboratories have gathered around the PRISTIFLEX project INTERREG IV. After a presentation of the manufacturing process and the characteristics of the piezo electric material developed in this study, we discussed modeling which helped to define the dimensional parameters of the piezo electric plate that composes the sensor. Then, the techniques for producing the electrodes (laserablation and inkjet printing) were presented and an example of performed electrode was provided. Finally, the effectiveness of these sensors from the measurement of the displacement caused by the surface wave excited by these IDT sensors were demonstrated. (author)

  19. Lunar Advanced Volatile Analysis Subsystem: Pressure Transducer Trade Study

    Science.gov (United States)

    Kang, Edward Shinuk

    2017-01-01

    In Situ Resource Utilization (ISRU) is a key factor in paving the way for the future of human space exploration. The ability to harvest resources on foreign astronomical objects to produce consumables and propellant offers potential reduction in mission cost and risk. Through previous missions, the existence of water ice at the poles of the moon has been identified, however the feasibility of water extraction for resources remains unanswered. The Resource Prospector (RP) mission is currently in development to provide ground truth, and will enable us to characterize the distribution of water at one of the lunar poles. Regolith & Environment Science and Oxygen & Lunar Volatile Extraction (RESOLVE) is the primary payload on RP that will be used in conjunction with a rover. RESOLVE contains multiple instruments for systematically identifying the presence of water. The main process involves the use of two systems within RESOLVE: the Oxygen Volatile Extraction Node (OVEN) and Lunar Advanced Volatile Analysis (LAVA). Within the LAVA subsystem, there are multiple calculations that depend on accurate pressure readings. One of the most important instances where pressure transducers (PT) are used is for calculating the number of moles in a gas transfer from the OVEN subsystem. As a critical component of the main process, a mixture of custom and commercial off the shelf (COTS) PTs are currently being tested in the expected operating environment to eventually down select an option for integrated testing in the LAVA engineering test unit (ETU).

  20. Electronic Current Transducer (ECT) for high voltage dc lines

    Science.gov (United States)

    Houston, J. M.; Peters, P. H., Jr.; Summerayes, H. R., Jr.; Carlson, G. J.; Itani, A. M.

    1980-02-01

    The development of a bipolar electronic current transducer (ECT) for measuring the current in a high voltage dc (HVDC) power line at line potential is discussed. The design and construction of a free standing ECT for use on a 400 kV line having a nominal line current of 2000 A is described. Line current is measured by a 0.0001 ohm shunt whose voltage output is sampled by a 14 bit digital data link. The high voltage interface between line and ground is traversed by optical fibers which carry digital light signals as far as 300 m to a control room where the digital signal is converted back to an analog representation of the shunt voltage. Two redundant electronic and optical data links are used in the prototype. Power to operate digital and optical electronics and temperature controlling heaters at the line is supplied by a resistively and capacitively graded 10 stage cascade of ferrite core transformers located inside the hollow, SF6 filled, porcelain support insulator. The cascade is driven by a silicon controlled rectifier inverter which supplies about 100 W of power at 30 kHz.

  1. Damage Identification of Wind Turbine Blades Using Piezoelectric Transducers

    Directory of Open Access Journals (Sweden)

    Seong-Won Choi

    2014-01-01

    Full Text Available This paper presents the experimental results of active-sensing structural health monitoring (SHM techniques, which utilize piezoelectric transducers as sensors and actuators, for determining the structural integrity of wind turbine blades. Specifically, Lamb wave propagations and frequency response functions at high frequency ranges are used to estimate the condition of wind turbine blades. For experiments, a 1 m section of a CX-100 blade is used. The goal of this study is to assess and compare the performance of each method in identifying incipient damage with a consideration given to field deployability. Overall, these methods yielded a sufficient damage detection capability to warrant further investigation. This paper also summarizes the SHM results of a full-scale fatigue test of a 9 m CX-100 blade using piezoelectric active sensors. This paper outlines considerations needed to design such SHM systems, experimental procedures and results, and additional issues that can be used as guidelines for future investigations.

  2. Bio-applications of ionic polymer metal composite transducers

    International Nuclear Information System (INIS)

    Aw, K C; McDaid, A J

    2014-01-01

    Traditional robotic actuators have advanced performance which in some aspects can surpass that of humans, however they are lacking when it comes to developing devices which are capable of operating together with humans. Bio-inspired transducers, for example ionic polymer metal composites (IPMC), which have similar properties to human tissue and muscle, demonstrate much future promise as candidates for replacing traditional robotic actuators in medical robotics applications. This paper outlines four biomedical robotics applications, an IPMC stepper motor, an assistive glove exoskeleton/prosthetic hand, a surgical robotic tool and a micromanipulation system. These applications have been developed using mechanical design/modelling techniques with IPMC ‘artificial muscle’ as the actuation system. The systems are designed by first simulating the performance using an IPMC model and dynamic models of the mechanical system; the appropriate advanced adaptive control schemes are then implemented to ensure that the IPMCs operate in the correct manner, robustly over time. This paper serves as an overview of the applications and concludes with some discussion on the future challenges of developing real-world IPMC applications

  3. Language Model Combination and Adaptation Using Weighted Finite State Transducers

    Science.gov (United States)

    Liu, X.; Gales, M. J. F.; Hieronymus, J. L.; Woodland, P. C.

    2010-01-01

    In speech recognition systems language model (LMs) are often constructed by training and combining multiple n-gram models. They can be either used to represent different genres or tasks found in diverse text sources, or capture stochastic properties of different linguistic symbol sequences, for example, syllables and words. Unsupervised LM adaption may also be used to further improve robustness to varying styles or tasks. When using these techniques, extensive software changes are often required. In this paper an alternative and more general approach based on weighted finite state transducers (WFSTs) is investigated for LM combination and adaptation. As it is entirely based on well-defined WFST operations, minimum change to decoding tools is needed. A wide range of LM combination configurations can be flexibly supported. An efficient on-the-fly WFST decoding algorithm is also proposed. Significant error rate gains of 7.3% relative were obtained on a state-of-the-art broadcast audio recognition task using a history dependently adapted multi-level LM modelling both syllable and word sequences

  4. Bio-applications of ionic polymer metal composite transducers

    Science.gov (United States)

    Aw, K. C.; McDaid, A. J.

    2014-07-01

    Traditional robotic actuators have advanced performance which in some aspects can surpass that of humans, however they are lacking when it comes to developing devices which are capable of operating together with humans. Bio-inspired transducers, for example ionic polymer metal composites (IPMC), which have similar properties to human tissue and muscle, demonstrate much future promise as candidates for replacing traditional robotic actuators in medical robotics applications. This paper outlines four biomedical robotics applications, an IPMC stepper motor, an assistive glove exoskeleton/prosthetic hand, a surgical robotic tool and a micromanipulation system. These applications have been developed using mechanical design/modelling techniques with IPMC ‘artificial muscle’ as the actuation system. The systems are designed by first simulating the performance using an IPMC model and dynamic models of the mechanical system; the appropriate advanced adaptive control schemes are then implemented to ensure that the IPMCs operate in the correct manner, robustly over time. This paper serves as an overview of the applications and concludes with some discussion on the future challenges of developing real-world IPMC applications.

  5. A rotary piezoelectric actuator using longitudinal and bending hybrid transducer

    Directory of Open Access Journals (Sweden)

    Yingxiang Liu

    2012-12-01

    Full Text Available A rotary piezoelectric actuator using bolt-clamped type transducer with double driving feet is proposed in this study. The first-order longitudinal and fourth-order bending vibration modes are superimposed in the actuator to produce elliptical movements on the driving tips. Longitudinal PZT and bending PZT are clamped between the exponential shape horns and the flange by bolts. The vibration shape changes of the actuator are presented to give a clear explanation of its working principle. Several structural parameters of the exponential shape horn are selected and adjusted to accomplish the tuning process of the longitudinal and bending resonance frequencies. The input impedance and vibration characteristics are calculated by using FEM method; the gained results verify the feasibility of the proposed actuator. After the fabrication of a prototype, its vibration characteristics are measured by using a scanning laser Doppler vibrometer; the tested results are in good agreement with the FEM calculated results. The mechanical output performance experiments state that the prototype achieves a maximum speed of 129 r/min and a maximum torque of 1.5 Nm.

  6. Variable reluctance displacement transducer temperature compensated to 6500F

    International Nuclear Information System (INIS)

    1975-01-01

    In pressurized water reactor tests, compact instruments for accurate measurement of small displacements in a 650 0 F environment are often required. In the case of blowdown tests such as the Loss of Fluid Test (LOFT) or Semiscale computer code development tests, not only is the initial environment water at 650 0 F and 2200 psi but it undergoes a severe transient due to depressurization. Since the LOFT and Semiscale tests are run just for the purpose of obtaining data during the depressurization, instruments used to obtain the data must not give false outputs induced by the change in environment. A LOFT rho v 2 probe and a Semiscale drag disk are described. Each utilizes a variable reluctance transducer (VRT) for indication of the drag-disk location and a torsion bar for drag-disk restoring force. The VRT, in addition to being thermally gain and null offset stable, is fabricated from materials known to be resistant to large nuclear radiation levels and has successfully passed a fast neutron radiation test of 2.7 x 10 17 nvt without failure

  7. Resonant gravimetric immunosensing based on capacitive micromachined ultrasound transducers

    KAUST Repository

    Viržonis, Darius

    2014-04-08

    High-frequency (40 MHz) and low-frequency (7 MHz) capacitive micromachined ultrasound transducers (CMUT) were fabricated and tested for use in gravimetric detection of biomolecules. The low-frequency CMUT sensors have a gold-coated surface, while the high-frequency sensors have a silicon nitride surface. Both surfaces were functionalized with bovine leukemia virus antigen gp51 acting as the antigen. On addition of an a specific antibody labeled with horseradish peroxidase (HRP), the antigen/antibody complex is formed on the surface and quantified by HRP-catalyzed oxidation of tetramethylbenzidine. It has been found that a considerably smaller quantity of immuno complex is formed on the high frequency sensor surface. In parallel, the loading of the surface of the CMUT was determined via resonance frequency and electromechanical resistance readings. Following the formation of the immuno complexes, the resonance frequencies of the low-frequency and high-frequency sensors decrease by up to 420 and 440 kHz, respectively. Finite element analysis reveals that the loading of the (gold-coated) low frequency sensors is several times larger than that on high frequency sensors. The formation of the protein film with pronounced elasticity and stress on the gold surface case is discussed. We also discuss the adoption of this method for the detection of DNA using a hybridization assay following polymerase chain reaction.

  8. Analysis on Coupled Vibration of a Radially Polarized Piezoelectric Cylindrical Transducer

    Directory of Open Access Journals (Sweden)

    Jie Xu

    2017-12-01

    Full Text Available Coupled vibration of a radially polarized piezoelectric cylindrical transducer is analyzed with the mechanical coupling coefficient method. The method has been utilized to analyze the metal cylindrical transducer and the axially polarized piezoelectric cylindrical transducer. In this method, the mechanical coupling coefficient is introduced and defined as the stress ratio in different directions. Coupled vibration of the cylindrical transducer is regarded as the interaction of the plane radial vibration of a ring and the longitudinal vibration of a tube. For the radially polarized piezoelectric cylindrical transducer, the radial and longitudinal electric admittances as functions of mechanical coupling coefficients and angular frequencies are derived, respectively. The resonance frequency equations are obtained. The dependence of resonance frequency and mechanical coupling coefficient on aspect ratio is studied. Vibrational distributions on the surfaces of the cylindrical transducer are presented with experimental measurement. On the support of experiments, this work is verified and provides a theoretical foundation for the analysis and design of the radially polarized piezoelectric cylindrical transducer.

  9. Structural model of standard ultrasonic transducer array developed for FEM analysis of mechanical crosstalk.

    Science.gov (United States)

    Celmer, M; Opieliński, K J; Dopierała, M

    2018-02-01

    One of the reasons of distortions in ultrasonic imaging are crosstalk effects. They can be divided into groups according to the way of their formation. One of them is constituted by mechanical crosstalk, which is propagated by a construction of a multi-element array of piezoelectric transducers. When an individual transducer is excited, mechanical vibrations are transferred to adjacent construction components, thereby stimulating neighboring transducers to an undesired operation. In order to explore ways of the propagation of such vibrations, the authors developed the FEM model of the array of piezoelectric transducers designed for calculations in COMSOL Multiphysics software. Simulations of activating individual transducers and calculated electrical voltages appearing on transducers unstimulated intentionally, were performed in the time domain in order to assess the propagation velocity of different vibration modes through the construction elements. On this basis, conclusions were drawn in terms of the participation of various construction parts of the array of piezoelectric transducers in the process of creating the mechanical crosstalk. The elaborated FEM model allowed also to examine the ways aimed at reducing the transmission of mechanical crosstalk vibrations through the components of the array. Studies showed that correct cuts in the fasteners and the front layer improve the reduction of the mechanical crosstalk effect. The model can become a helpful tool in the process of design and modifications of manufactured ultrasonic arrays particularly in terms of mechanical crosstalk reduction. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. High Performance Relaxor-Based Ferroelectric Single Crystals for Ultrasonic Transducer Applications

    Directory of Open Access Journals (Sweden)

    Yan Chen

    2014-07-01

    Full Text Available Relaxor-based ferroelectric single crystals Pb(Mg1/3Nb2/3O3-PbTiO3 (PMN-PT have drawn much attention in the ferroelectric field because of their excellent piezoelectric properties and high electromechanical coupling coefficients (d33~2000 pC/N, kt~60% near the morphotropic phase boundary (MPB. Ternary Pb(In1/2Nb1/2O3-Pb(Mg1/3Nb2/3O3-PbTiO3 (PIN-PMN-PT single crystals also possess outstanding performance comparable with PMN-PT single crystals, but have higher phase transition temperatures (rhombohedral to tetragonal Trt, and tetragonal to cubic Tc and larger coercive field Ec. Therefore, these relaxor-based single crystals have been extensively employed for ultrasonic transducer applications. In this paper, an overview of our work and perspectives on using PMN-PT and PIN-PMN-PT single crystals for ultrasonic transducer applications is presented. Various types of single-element ultrasonic transducers, including endoscopic transducers, intravascular transducers, high-frequency and high-temperature transducers fabricated using the PMN-PT and PIN-PMN-PT crystals and their 2-2 and 1-3 composites are reported. Besides, the fabrication and characterization of the array transducers, such as phased array, cylindrical shaped linear array, high-temperature linear array, radial endoscopic array, and annular array, are also addressed.

  11. Magnetically responsive enzyme powders

    Czech Academy of Sciences Publication Activity Database

    Pospišková, K.; Šafařík, Ivo

    2015-01-01

    Roč. 380, APR 2015 (2015), s. 197-200 ISSN 0304-8853 R&D Projects: GA MŠk(CZ) LD13021 Institutional support: RVO:67179843 Keywords : enzyme powders * cross-linking * magnetic modification * magnetic separation * magnetic iron oxides particles * microwave-assisted synthesis Subject RIV: CE - Biochemistry Impact factor: 2.357, year: 2015

  12. Enzyme with rhamnogalacturonase activity.

    NARCIS (Netherlands)

    Kofod, L.V.; Andersen, L.N.; Dalboge, H.; Kauppinen, M.S.; Christgau, S.; Heldt-Hansen, H.P.; Christophersen, C.; Nielsen, P.M.; Voragen, A.G.J.; Schols, H.A.

    1998-01-01

    An enzyme exhibiting rhamnogalacturonase activity, capable of cleaving a rhamnogalacturonan backbone in such a manner that galacturonic acids are left as the non-reducing ends, and which exhibits activity on hairy regions from a soy bean material and/or on saponified hairy regions from a sugar beet

  13. Implantable enzyme amperometric biosensors.

    Science.gov (United States)

    Kotanen, Christian N; Moussy, Francis Gabriel; Carrara, Sandro; Guiseppi-Elie, Anthony

    2012-05-15

    The implantable enzyme amperometric biosensor continues as the dominant in vivo format for the detection, monitoring and reporting of biochemical analytes related to a wide range of pathologies. Widely used in animal studies, there is increasing emphasis on their use in diabetes care and management, the management of trauma-associated hemorrhage and in critical care monitoring by intensivists in the ICU. These frontier opportunities demand continuous indwelling performance for up to several years, well in excess of the currently approved seven days. This review outlines the many challenges to successful deployment of chronically implantable amperometric enzyme biosensors and emphasizes the emerging technological approaches in their continued development. The foreign body response plays a prominent role in implantable biotransducer failure. Topics considering the approaches to mitigate the inflammatory response, use of biomimetic chemistries, nanostructured topographies, drug eluting constructs, and tissue-to-device interface modulus matching are reviewed. Similarly, factors that influence biotransducer performance such as enzyme stability, substrate interference, mediator selection and calibration are reviewed. For the biosensor system, the opportunities and challenges of integration, guided by footprint requirements, the limitations of mixed signal electronics, and power requirements, has produced three systems approaches. The potential is great. However, integration along the multiple length scales needed to address fundamental issues and integration across the diverse disciplines needed to achieve success of these highly integrated systems, continues to be a challenge in the development and deployment of implantable amperometric enzyme biosensor systems. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Cold-Adapted Enzymes

    Science.gov (United States)

    Georlette, D.; Bentahir, M.; Claverie, P.; Collins, T.; D'amico, S.; Delille, D.; Feller, G.; Gratia, E.; Hoyoux, A.; Lonhienne, T.; Meuwis, M.-a.; Zecchinon, L.; Gerday, Ch.

    In the last few years, increased attention has been focused on enzymes produced by cold-adapted micro-organisms. It has emerged that psychrophilic enzymes represent an extremely powerful tool in both protein folding investigations and for biotechnological purposes. Such enzymes are characterised by an increased thermosensitivity and, most of them, by a higher catalytic efficiency at low and moderate temperatures, when compared to their mesophilic counterparts. The high thermosensitivity probably originates from an increased flexibility of either a selected area of the molecular edifice or the overall protein structure, providing enhanced abilities to undergo conformational changes during catalysis at low temperatures. Structure modelling and recent crystallographic data have allowed to elucidate the structural parameters that could be involved in this higher resilience. It was demonstrated that each psychrophilic enzyme adopts its own adaptive strategy. It appears, moreover, that there is a continuum in the strategy of protein adaptation to temperature, as the previously mentioned structural parameters are implicated in the stability of thermophilic proteins. Additional 3D crystal structures, site-directed and random mutagenesis experiments should now be undertaken to further investigate the stability-flexibility-activity relationship.

  15. Embedded enzymes catalyse capture

    Science.gov (United States)

    Kentish, Sandra

    2018-05-01

    Membrane technologies for carbon capture can offer economic and environmental advantages over conventional amine-based absorption, but can suffer from limited gas flux and selectivity to CO2. Now, a membrane based on enzymes embedded in hydrophilic pores is shown to exhibit combined flux and selectivity that challenges the state of the art.

  16. Photoperiodism and Enzyme Activity

    Science.gov (United States)

    Queiroz, Orlando; Morel, Claudine

    1974-01-01

    Metabolic readjustments after a change from long days to short days appear, in Kalanchoe blossfeldiana, to be achieved through the operation of two main mechanisms: variation in enzyme capacity, and circadian rhythmicity. After a lag time, capacity in phosphoenolpyruvate carboxylase and capacity in aspartate aminotransferase increase exponentially and appear to be allometrically linked during 50 to 60 short days; then a sudden fall takes place in the activity of the former. Malic enzyme and alanine aminotransferase behave differently. Thus, the operation of the two sections of the pathway (before and after the malate step) give rise to a continuously changing functional compartmentation in the pathway. Circadian rhythmicity, on the other hand, produces time compartmentation through phase shifts and variation in amplitude, independently for each enzyme. These characteristics suggest that the operation of a so-called biological clock would be involved. We propose the hypothesis that feedback regulation would be more accurate and efficient when applied to an already oscillating, clock-controlled enzyme system. PMID:16658749

  17. ISFET based enzyme sensors

    NARCIS (Netherlands)

    van der Schoot, Bart H.; Bergveld, Piet

    1987-01-01

    This paper reviews the results that have been reported on ISFET based enzyme sensors. The most important improvement that results from the application of ISFETs instead of glass membrane electrodes is in the method of fabrication. Problems with regard to the pH dependence of the response and the

  18. The Enzyme Function Initiative†

    Science.gov (United States)

    Gerlt, John A.; Allen, Karen N.; Almo, Steven C.; Armstrong, Richard N.; Babbitt, Patricia C.; Cronan, John E.; Dunaway-Mariano, Debra; Imker, Heidi J.; Jacobson, Matthew P.; Minor, Wladek; Poulter, C. Dale; Raushel, Frank M.; Sali, Andrej; Shoichet, Brian K.; Sweedler, Jonathan V.

    2011-01-01

    The Enzyme Function Initiative (EFI) was recently established to address the challenge of assigning reliable functions to enzymes discovered in bacterial genome projects; in this Current Topic we review the structure and operations of the EFI. The EFI includes the Superfamily/Genome, Protein, Structure, Computation, and Data/Dissemination Cores that provide the infrastructure for reliably predicting the in vitro functions of unknown enzymes. The initial targets for functional assignment are selected from five functionally diverse superfamilies (amidohydrolase, enolase, glutathione transferase, haloalkanoic acid dehalogenase, and isoprenoid synthase), with five superfamily-specific Bridging Projects experimentally testing the predicted in vitro enzymatic activities. The EFI also includes the Microbiology Core that evaluates the in vivo context of in vitro enzymatic functions and confirms the functional predictions of the EFI. The deliverables of the EFI to the scientific community include: 1) development of a large-scale, multidisciplinary sequence/structure-based strategy for functional assignment of unknown enzymes discovered in genome projects (target selection, protein production, structure determination, computation, experimental enzymology, microbiology, and structure-based annotation); 2) dissemination of the strategy to the community via publications, collaborations, workshops, and symposia; 3) computational and bioinformatic tools for using the strategy; 4) provision of experimental protocols and/or reagents for enzyme production and characterization; and 5) dissemination of data via the EFI’s website, enzymefunction.org. The realization of multidisciplinary strategies for functional assignment will begin to define the full metabolic diversity that exists in nature and will impact basic biochemical and evolutionary understanding, as well as a wide range of applications of central importance to industrial, medicinal and pharmaceutical efforts. PMID

  19. The Enzyme Function Initiative.

    Science.gov (United States)

    Gerlt, John A; Allen, Karen N; Almo, Steven C; Armstrong, Richard N; Babbitt, Patricia C; Cronan, John E; Dunaway-Mariano, Debra; Imker, Heidi J; Jacobson, Matthew P; Minor, Wladek; Poulter, C Dale; Raushel, Frank M; Sali, Andrej; Shoichet, Brian K; Sweedler, Jonathan V

    2011-11-22

    The Enzyme Function Initiative (EFI) was recently established to address the challenge of assigning reliable functions to enzymes discovered in bacterial genome projects; in this Current Topic, we review the structure and operations of the EFI. The EFI includes the Superfamily/Genome, Protein, Structure, Computation, and Data/Dissemination Cores that provide the infrastructure for reliably predicting the in vitro functions of unknown enzymes. The initial targets for functional assignment are selected from five functionally diverse superfamilies (amidohydrolase, enolase, glutathione transferase, haloalkanoic acid dehalogenase, and isoprenoid synthase), with five superfamily specific Bridging Projects experimentally testing the predicted in vitro enzymatic activities. The EFI also includes the Microbiology Core that evaluates the in vivo context of in vitro enzymatic functions and confirms the functional predictions of the EFI. The deliverables of the EFI to the scientific community include (1) development of a large-scale, multidisciplinary sequence/structure-based strategy for functional assignment of unknown enzymes discovered in genome projects (target selection, protein production, structure determination, computation, experimental enzymology, microbiology, and structure-based annotation), (2) dissemination of the strategy to the community via publications, collaborations, workshops, and symposia, (3) computational and bioinformatic tools for using the strategy, (4) provision of experimental protocols and/or reagents for enzyme production and characterization, and (5) dissemination of data via the EFI's Website, http://enzymefunction.org. The realization of multidisciplinary strategies for functional assignment will begin to define the full metabolic diversity that exists in nature and will impact basic biochemical and evolutionary understanding, as well as a wide range of applications of central importance to industrial, medicinal, and pharmaceutical efforts.

  20. Study of a Modified Displacement Transducer of a Piston in a Power Cylinder

    Directory of Open Access Journals (Sweden)

    S. C. BERA

    2011-05-01

    Full Text Available The position monitoring of the piston inside a power cylinder is very important in process plant measurement and control. In the present paper a modified inductance type position sensing technique of a power cylinder piston has been described. A modified inductance measuring transducer circuit has been designed to measure the change of inductance of a very high inductance coil. The theoretical equations of the proposed inductive sensor and the displacement transducer have been derived. The transducer has been experimentally tested and the experimental data are presented in the paper.

  1. Hysteretic self-oscillating bandpass current mode control for Class D audio amplifiers driving capacitive transducers

    DEFF Research Database (Denmark)

    Nielsen, Dennis; Knott, Arnold; Andersen, Michael A. E.

    2013-01-01

    A hysteretic self-oscillating bandpass current mode control (BPCM) scheme for Class D audio amplifiers driving capacitive transducers are presented. The scheme provides excellent stability margins and low distortion over a wide range of operating conditions. Small-signal behavior of the amplifier...... the rules of electrostatics have been known as very interesting alternatives to the traditional inefficient electrodynamic transducers. When driving capacitive transducers from a Class D audio amplifier the high impedance nature of the load represents a key challenge. The BPCM control scheme ensures a flat...

  2. Angle transducer based on fiber Bragg gratings able for tunnel auscultation

    Science.gov (United States)

    Quintela, A.; Lázaro, J. M.; Quintela, M. A.; Mirapeix, J.; Muñoz-Berti, V.; López-Higuera, J. M.

    2010-09-01

    In this paper an angle transducer based on Fiber Bragg Grating (FBG) is presented. Two gratings are glued to a metallic platen, one in each side. It is insensitive to temperature changes, given that the temperature shifts affect equally to both FBG. When the platen is uniformly bent an uniform strain appears in both sides of the platen. It depends on the bend angle and the platen length and thickness. The transducer has been designed to be used in the auscultation of tunnels during their construction process and during their live time. The transducer design and its characterization are presented.

  3. Influence of Ultrasonic Nonlinear Propagation on Hydrophone Calibration Using Two-Transducer Reciprocity Method

    Science.gov (United States)

    Yoshioka, Masahiro; Sato, Sojun; Kikuchi, Tsuneo; Matsuda, Yoichi

    2006-05-01

    In this study, the influence of ultrasonic nonlinear propagation on hydrophone calibration by the two-transducer reciprocity method is investigated quantitatively using the Khokhlov-Zabolotskaya-Kuznetsov (KZK) equation. It is proposed that the correction for the diffraction and attenuation of ultrasonic waves used in two-transducer reciprocity calibration can be derived using the KZK equation to remove the influence of nonlinear propagation. The validity of the correction is confirmed by comparing the sensitivities calibrated by the two-transducer reciprocity method and laser interferometry.

  4. Overweight, insulin resistance and type II diabetes in type I Gaucher disease patients in relation to enzyme replacement therapy

    NARCIS (Netherlands)

    Langeveld, M.; de Fost, M.; Aerts, J. M. F. G.; Sauerwein, H. P.; Hollak, C. E. M.

    2008-01-01

    Type I Gaucher disease, a lysosomal storage disorder is associated with metabolic abnormalities such as high resting energy expenditure, low circulating adiponectin and peripheral insulin resistance. Treatment with enzyme replacement therapy (enzyme therapy) leads to a decrease in resting energy

  5. Subunit topology in the V type ATPase and related enzymes

    NARCIS (Netherlands)

    Chaban, Yuriy

    2005-01-01

    During the last decades impressive progress has been made in understanding of the catalytic mechanism of F-type ATP synthase, which is the key enzyme in the energy metabolism of eukaryotes and most bacteria. This enzyme catalyzes the final step in the process of oxidative phosphorylation in bacteria

  6. Chemical vapor detection using a capacitive micromachined ultrasonic transducer.

    Science.gov (United States)

    Lee, Hyunjoo J; Park, Kwan Kyu; Kupnik, Mario; Oralkan, O; Khuri-Yakub, Butrus T

    2011-12-15

    Distributed sensing of gas-phase chemicals using highly sensitive and inexpensive sensors is of great interest for many defense and consumer applications. In this paper we present ppb-level detection of dimethyl methylphosphonate (DMMP), a common simulant for sarin gas, with a ppt-level resolution using an improved capacitive micromachined ultrasonic transducer (CMUT) as a resonant chemical sensor. The improved CMUT operates at a higher resonant frequency of 47.7 MHz and offers an improved mass sensitivity of 48.8 zg/Hz/μm(2) by a factor of 2.7 compared to the previous CMUT sensors developed. A low-noise oscillator using the CMUT resonant sensor as the frequency-selective device was developed for real-time sensing, which exhibits an Allan deviation of 1.65 Hz (3σ) in the presence of a gas flow; this translates into a mass resolution of 80.5 zg/μm(2). The CMUT resonant sensor is functionalized with a 50-nm thick DKAP polymer developed at Sandia National Laboratory for dimethyl methylphosphonate (DMMP) detection. To demonstrate ppb-level detection of the improved chemical sensor system, the sensor performance was tested at a certified lab (MIT Lincoln Laboratory), which is equipped with an experimental chemical setup that reliably and accurately delivers a wide range of low concentrations down to 10 ppb. We report a high volume sensitivity of 34.5 ± 0.79 pptv/Hz to DMMP and a good selectivity of the polymer to DMMP with respect to dodecane and 1-octanol.

  7. Nanomechanical probing of thin-film dielectric elastomer transducers

    Science.gov (United States)

    Osmani, Bekim; Seifi, Saman; Park, Harold S.; Leung, Vanessa; Töpper, Tino; Müller, Bert

    2017-08-01

    Dielectric elastomer transducers (DETs) have attracted interest as generators, actuators, sensors, and even as self-sensing actuators for applications in medicine, soft robotics, and microfluidics. Their performance crucially depends on the elastic properties of the electrode-elastomer sandwich structure. The compressive displacement of a single-layer DET can be easily measured using atomic force microscopy (AFM) in the contact mode. While polymers used as dielectric elastomers are known to exhibit significant mechanical stiffening for large strains, their mechanical properties when subjected to voltages are not well understood. To examine this effect, we measured the depths of 400 nanoindentations as a function of the applied electric field using a spherical AFM probe with a radius of (522 ± 4) nm. Employing a field as low as 20 V/μm, the indentation depths increased by 42% at a load of 100 nN with respect to the field-free condition, implying an electromechanically driven elastic softening of the DET. This at-a-glance surprising experimental result agrees with related nonlinear, dynamic finite element model simulations. Furthermore, the pull-off forces rose from (23.0 ± 0.4) to (49.0 ± 0.7) nN implying a nanoindentation imprint after unloading. This embossing effect is explained by the remaining charges at the indentation site. The root-mean-square roughness of the Au electrode raised by 11% upon increasing the field from zero to 12 V/μm, demonstrating that the electrode's morphology change is an undervalued factor in the fabrication of DET structures.

  8. Reliability and Validity Assessment of a Linear Position Transducer

    Directory of Open Access Journals (Sweden)

    Manuel V. Garnacho-Castaño

    2015-03-01

    Full Text Available The objectives of the study were to determine the validity and reliability of peak velocity (PV, average velocity (AV, peak power (PP and average power (AP measurements were made using a linear position transducer. Validity was assessed by comparing measurements simultaneously obtained using the Tendo Weightlifting Analyzer Systemi and T-Force Dynamic Measurement Systemr (Ergotech, Murcia, Spain during two resistance exercises, bench press (BP and full back squat (BS, performed by 71 trained male subjects. For the reliability study, a further 32 men completed both lifts using the Tendo Weightlifting Analyzer Systemz in two identical testing sessions one week apart (session 1 vs. session 2. Intraclass correlation coefficients (ICCs indicating the validity of the Tendo Weightlifting Analyzer Systemi were high, with values ranging from 0.853 to 0.989. Systematic biases and random errors were low to moderate for almost all variables, being higher in the case of PP (bias ±157.56 W; error ±131.84 W. Proportional biases were identified for almost all variables. Test-retest reliability was strong with ICCs ranging from 0.922 to 0.988. Reliability results also showed minimal systematic biases and random errors, which were only significant for PP (bias -19.19 W; error ±67.57 W. Only PV recorded in the BS showed no significant proportional bias. The Tendo Weightlifting Analyzer Systemi emerged as a reliable system for measuring movement velocity and estimating power in resistance exercises. The low biases and random errors observed here (mainly AV, AP make this device a useful tool for monitoring resistance training.

  9. Investigation of bulk acoustic microwaves excited by an interdigital transducer

    Directory of Open Access Journals (Sweden)

    Reshotka O. G.

    2015-12-01

    Full Text Available Excitation of bulk and surface acoustic waves with the interdigital transducer (IDT, which is deposited on the surface of piezoelectric crystal, is widely used in the development of devices in acoustoelectronics and in the design of the microwave acousto-optic deflectors. Excitation of bulk acoustic waves by IDT in the devices on surface acoustic waves leads to the appearance of spurious signals. At the same time excitation of bulk acoustic waves with IDT from the surface of lithium niobate crystals allows creating high frequency acousto-optic deflectors, which makes possible to significantly simplify the technology of their production. Therefore, significant attention is paid to the task of excitation and distribution of bulk acoustic waves with IDT including recent times by the method of simulation of their excitation and distribution. The obtained theoretical results require experimental verification. This paper documents the visualization of acoustic beams excited with IDT from the XY-surface of lithium niobate crystals. The Bragg cells with LiNbO3 crystals coated with IDT with a different period of electrodes were manufactured for the experimental research of excitation and distribution of bulk acoustic waves. Visualization results have shown that the acoustic waves excited with IDT distribute in both the Fresnel zone and the Fraunhofer zone. The length of these zones is caused by individual elementary emitters of which consists the IDT (by their size. At the same time the far zone for IDT is located at distances much greater than the actual size of the LiNbO3 crystals. This peculiarity is not always taken into account when calculating diffraction. The achieved results can be used to design high-frequency acousto-optic devices, as well as in the development of devices based on surface acoustic waves.

  10. Ethanologenic Enzymes of Zymomonas mobilis

    Energy Technology Data Exchange (ETDEWEB)

    Ingram, Lonnie O' Neal

    1999-03-01

    Zymomonas mobilis is a unique microorganism in being both obligately fermentative and utilizing a Entner-Doudoroff pathway for glycolysis. Glycolytic flux in this organism is readily measured as evolved carbon dioxide, ethanol, or glucose consumed and exceeds 1 {micro}mole glucose/min per mg cell protein. To support this rapid glycolysis, approximately 50% of cytoplasmic protein is devoted to the 13 glycolytic and fermentative enzymes which constitute this central catabolic pathway. Only 1 ATP (net) is produced from each glucose metabolized. During the past grant period, we have completed the characterization of 11 of the 13 glycolytic genes from Z. mobilis together with complementary but separate DOE-fimded research by a former post-dot and collaborator, Dr. Tyrrell Conway. Research funded in my lab by DOE, Division of Energy Biosciences can be divided into three sections: A. Fundamental studies; B. Applied studies and utility; and C. Miscellaneous investigations.

  11. Response of an oscillating superleak transducer to a pointlike heat source

    Directory of Open Access Journals (Sweden)

    A. Quadt

    2012-03-01

    Full Text Available A new technique of superconducting cavity diagnostics has been introduced by D. L. Hartill at Cornell University, Ithaca, New York. It uses oscillating superleak transducers (OST which detect the heat transferred from a cavity’s quench point via Second Sound through the superfluid He bath, needed to cool the superconducting cavity. The localization of the quench point is done by triangulation. The observed response of an OST is a nontrivial, but reproducible pattern of oscillations. A small helium evaporation cryostat was built which allows the investigation of the response of an OST in greater detail. The distance between a pointlike electrical heater and the OST can be varied. The OST can be mounted either parallel or perpendicular to the plate that houses the heat source. If the artificial quench point releases an amount of energy compatible to a real quench spot on a cavity’s surface, the OST signal starts with a negative pulse, which is usually strong enough to allow automatic detection. Furthermore, the reflection of the Second Sound on the wall is observed. A reflection coefficient R=0.39±0.05 of the glass wall is measured. This excludes a strong influence of multiple reflections in the complex OST response. Fourier analyses show three main frequencies, found in all OST spectra. They can be interpreted as modes of an oscillating circular membrane.

  12. Research on Stabilization Properties of Inductive-Capacitive Transducers Based on Hybrid Electromagnetic Elements

    Science.gov (United States)

    Konesev, S. G.; Khazieva, R. T.; Kirllov, R. V.; Konev, A. A.

    2017-01-01

    Some electrical consumers (the charge system of storage capacitor, powerful pulse generators, electrothermal systems, gas-discharge lamps, electric ovens, plasma torches) require constant power consumption, while their resistance changes in the limited range. Current stabilization systems (CSS) with inductive-capacitive transducers (ICT) provide constant power, when the load resistance changes over a wide range and increaseы the efficiency of high-power loads’ power supplies. ICT elements are selected according to the maximum load, which leads to exceeding a predetermined value of capacity. The paper suggests carrying load power by the ICT based on multifunction integrated electromagnetic components (MIEC) to reduce the predetermined capacity of ICT elements and CSS weights and dimensions. The authors developed and patented ICT based on MIEC that reduces the CSS weights and dimensions by reducing components number with the possibility of device’s electric energy transformation and resonance frequency changing. An ICT mathematical model was produced. The model determines the width of the load stabilization range. Electromagnetic processes study model was built with the MIEC integral parameters (full inductance of the electrical lead, total capacity, current of electrical lead). It shows independence of the load current from the load resistance for different ways of MIEC connection.

  13. A review of piezoelectric polymers as functional materials for electromechanical transducers

    International Nuclear Information System (INIS)

    Ramadan, Khaled S; Evoy, S; Sameoto, D

    2014-01-01

    Polymer based MEMS and microfluidic devices have the advantages of mechanical flexibility, lower fabrication cost and faster processing over silicon based ones. Also, many polymer materials are considered biocompatible and can be used in biological applications. A valuable class of polymers for microfabricated devices is piezoelectric functional polymers. In addition to the normal advantages of polymers, piezoelectric polymers can be directly used as an active material in different transduction applications. This paper gives an overview of piezoelectric polymers based on their operating principle. This includes three main categories: bulk piezoelectric polymers, piezocomposites and voided charged polymers. State-of-the-art piezopolymers of each category are presented with a focus on fabrication techniques and material properties. A comparison between the different piezoelectric polymers and common inorganic piezoelectric materials (PZT, ZnO, AlN and PMN–PT) is also provided in terms of piezoelectric properties. The use of piezopolymers in different electromechanical devices is also presented. This includes tactile sensors, energy harvesters, acoustic transducers and inertial sensors. (topical review)

  14. Dynamic Mode Tuning of Ultrasonic Guided Wave Using an Array Transducer

    International Nuclear Information System (INIS)

    Kim, Young H.; Song, Sung J.; Park, Joon S.; Kim, Jae H.; Eom, Heung S.

    2005-01-01

    Ultrasonic guided waves have been widely employed for long range inspection of structures such as plates, rods and pipes. There are numerous modes with different wave velocities, and the appropriate mode selection is one of key techniques in the application of guided waves. In the present work, phase tuning by an array transducer was applied to generate ultrasonic guided waves. For this purpose, 8-channel ultrasonic pulser/receiver and their controller which enables sequential activation of each channels with given time delay were developed. Eight transducers were fabricated in order to generate guided waves by using an array transducer. The selective tuning of wave mode can be achieved by changing the interval between elements of an array transducer

  15. Actuatable capacitive transducer for quantitative nanoindentation combined with transmission electron microscopy

    Science.gov (United States)

    Warren, Oden L.; Asif, S. A. Syed; Cyrankowski, Edward; Kounev, Kalin

    2010-09-21

    An actuatable capacitive transducer including a transducer body, a first capacitor including a displaceable electrode and electrically configured as an electrostatic actuator, and a second capacitor including a displaceable electrode and electrically configured as a capacitive displacement sensor, wherein the second capacitor comprises a multi-plate capacitor. The actuatable capacitive transducer further includes a coupling shaft configured to mechanically couple the displaceable electrode of the first capacitor to the displaceable electrode of the second capacitor to form a displaceable electrode unit which is displaceable relative to the transducer body, and an electrically-conductive indenter mechanically coupled to the coupling shaft so as to be displaceable in unison with the displaceable electrode unit.-

  16. Ultrasonic field analysis program for transducer design in the nuclear industry

    International Nuclear Information System (INIS)

    Singh, G.P.; Rose, J.L.

    1980-02-01

    An ultrasonic field analysis program is presented that can be used for transducer design in the nuclear industry. Calculation routines that make use of Huygen's principle in a field analysis model are introduced that enable such field characteristics as axial and lateral resolution, beam symmetry, and gain variation throughout the ultrasonic field to be optimized. Mathematical details are presented along with several sample problems that show comparisons with classical results reported in the literature and with experimental data. Several sample problems that are of interest to the nuclear industry are also included, along with some that satisfy both academical and practical curiosity. These include transducer shape effects, pulse shape effects, crystal vibration variation, and an introduction to such novel transducer designs as annular arrays and dual element angle beam transducers

  17. Lead-free piezoelectric materials and ultrasonic transducers for medical imaging

    Directory of Open Access Journals (Sweden)

    Elaheh Taghaddos

    2015-06-01

    Full Text Available Piezoelectric materials have been vastly used in ultrasonic transducers for medical imaging. In this paper, firstly, the most promising lead-free compositions with perovskite structure for medical imaging applications have been reviewed. The electromechanical properties of various lead-free ceramics, composites, and single crystals based on barium titanate, bismuth sodium titanate, potassium sodium niobate, and lithium niobate are presented. Then, fundamental principles and design considerations of ultrasonic transducers are briefly described. Finally, recent developments in lead-free ultrasonic probes are discussed and their acoustic performance is compared to lead-based transducers. Focused transducers with different beam focusing methods such as lens focusing and mechanical shaping are explained. Additionally, acoustic characteristics of lead-free probes including the pulse-echo results as well as their imaging capabilities for various applications such as phantom imaging, in vitro intravascular ultrasound imaging of swine aorta, and in vivo or ex vivo imaging of human eyes and skin are reviewed.

  18. Practical ultrasonic transducers for high-temperature applications using bismuth titanate and Ceramabind 830

    Science.gov (United States)

    Xu, Janet L.; Batista, Caio F. G.; Tittmann, Bernhard R.

    2018-04-01

    Structural health monitoring of large valve bodies in high-temperature environments such as power plants faces several limitations: commercial transducers are not rated for such high temperatures, gel couplants will evaporate, and measurements cannot be made in-situ. To solve this, we have furthered the work of Ledford in applying a practical transducer in liquid form which hardens and air dries directly onto the substrate. The transducer material is a piezoceramic film composed of bismuth titanate and a high-temperature binding agent, Ceramabind 830. The effects of several fabrication conditions were studied to optimize transducer performance and ensure repeatability. These fabrication conditions include humidity, binder ratio, water ratio, substrate roughness, and film thickness. The final product is stable for both reactive and non-reactive substrates, has a quick fabrication time, and has an operating temperature up to the Curie temperature of BIT, 650°C, well beyond the safe operating temperature of PZT (150°C).

  19. Basic technical parameters of magnetometers with ferromagnetic transducers and a method to define them

    International Nuclear Information System (INIS)

    Nagiello, Z.

    1980-01-01

    The basic technical parameters of magnetometers with ferromagnetic transducers and measuring methods to define these parameters have been discussed. Special attention was paid to factors which essentially affect the inaccuracy of these measuring instruments. (author)

  20. Positioning calibration apparatus for transducers employed in nuclear reactor vessel inspection apparatus

    International Nuclear Information System (INIS)

    Elsner, H.J.

    1979-01-01

    Calibration apparatus for verifying the position and orientation of transducers used in nuclear reactor vessel inspection apparatus is disclosed. A tank, filled with water, the operating inspection medium, is fitted with a movable mounting assembly adapted to securely accommodate a transducer and the mounting assembly in which it is normally secured during an inspection procedure. The tank is also provided with a slidably mounted target positioned therein at a predetermined distance from the target which is selected to avoid the distortion effects in the near field of the transducer response. The calibration apparatus can be used to check the normal transducer mounting for either perpendicularity or angular orientation by moving the tank's mounting assembly via a lead screw with which it is threadingly engaged. 6 claims