BAYESIAN INFERENCE OF CMB GRAVITATIONAL LENSING

Energy Technology Data Exchange (ETDEWEB)

Anderes, Ethan [Department of Statistics, University of California, Davis, CA 95616 (United States); Wandelt, Benjamin D.; Lavaux, Guilhem [Sorbonne Universités, UPMC Univ Paris 06 and CNRS, UMR7095, Institut d’Astrophysique de Paris, F-75014, Paris (France)

2015-08-01

The Planck satellite, along with several ground-based telescopes, has mapped the cosmic microwave background (CMB) at sufficient resolution and signal-to-noise so as to allow a detection of the subtle distortions due to the gravitational influence of the intervening matter distribution. A natural modeling approach is to write a Bayesian hierarchical model for the lensed CMB in terms of the unlensed CMB and the lensing potential. So far there has been no feasible algorithm for inferring the posterior distribution of the lensing potential from the lensed CMB map. We propose a solution that allows efficient Markov Chain Monte Carlo sampling from the joint posterior of the lensing potential and the unlensed CMB map using the Hamiltonian Monte Carlo technique. The main conceptual step in the solution is a re-parameterization of CMB lensing in terms of the lensed CMB and the “inverse lensing” potential. We demonstrate a fast implementation on simulated data, including noise and a sky cut, that uses a further acceleration based on a very mild approximation of the inverse lensing potential. We find that the resulting Markov Chain has short correlation lengths and excellent convergence properties, making it promising for applications to high-resolution CMB data sets in the future.

Adiabatic CMB perturbations in pre-big bang string cosmology

DEFF Research Database (Denmark)

Enqvist, Kari; Sloth, Martin Snoager

2001-01-01

We consider the pre-big bang scenario with a massive axion field which starts to dominate energy density when oscillating in an instanton-induced potential and subsequently reheats the universe as it decays into photons, thus creating adiabatic CMB perturbations. We find that the fluctuations...

CMB lensing and giant rings

Energy Technology Data Exchange (ETDEWEB)

Rathaus, Ben; Itzhaki, Nissan, E-mail: nitzhaki@post.tau.ac.il, E-mail: ben.rathaus@gmail.com [Raymond and Beverly Sackler Faculty of Exact Sciences, School of Physics and Astronomy, Tel-Aviv University, Ramat-Aviv, 69978 (Israel)

2012-05-01

We study the CMB lensing signature of a pre-inationary particle (PIP), assuming it is responsible for the giant rings anomaly that was found recently in the WMAP data. Simulating Planck-like data we find that generically the CMB lensing signal to noise ratio associated with such a PIP is quite small and it would be difficult to cross correlate the temperature giant rings with the CMB lensing signal. However, if the pre-inationary particle is also responsible for the bulk flow measured from the local large scale structure, which happens to point roughly at the same direction as the giant rings, then the CMB lensing signal to noise ratio is fairly significant.

CMB lensing forecasts for constraining the primordial perturbations: adding to the CMB temperature and polarization information

Energy Technology Data Exchange (ETDEWEB)

Kasanda, Simon Muya; Moodley, Kavilan, E-mail: simon.muya.kasanda@gmail.com, E-mail: moodleyk41@ukzn.ac.za [Astrophysics and Cosmology Research Unit and School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, University Road, Durban, 4041 (South Africa)

2014-12-01

We forecast how current (PLANCK) and future (PRISM) cosmic microwave background (CMB) experiments constrain the adiabatic mode and its admixtures with primordial isocurvature modes. The forecasts are based on measurements of the reconstructed CMB lensing potential and lensing-induced CMB B-mode polarization anisotropies in combination with the CMB temperature and E-mode polarization anisotropies. We first study the characteristic features of the CMB temperature, polarization and lensing spectra for adiabatic and isocurvature modes. We then consider how information from the CMB lensing potential and B-mode polarization induced by lensing can improve constraints on an admixture of adiabatic and three correlated isocurvature modes. We find that the CMB lensing spectrum improves constraints on isocurvature modes by at most 10% for the PLANCK and PRISM experiments. The limited improvement is a result of the low amplitude of isocurvature lensing spectra and cancellations between these spectra that render them only slightly detectable. There is a larger gain from using the lensing-induced B-mode polarization spectrum measured by PRISM. In this case constraints on isocurvature mode amplitudes improve by as much as 40% relative to the CMB temperature and E-mode polarization constraints. The addition of both lensing and lensing-induced B-mode polarization information constrains isocurvature mode amplitudes at the few percent level or better. In the case of admixtures of the adiabatic mode with one or two correlated isocurvature modes we find that constraints at the percent level or better are possible. We investigate the dependence of our results to various assumptions in our analysis, such as the inclusion of dark energy parameters, the CMB temperature-lensing correlation, and the presence of primordial tensor modes, and find that these assumptions do not significantly change our main results.

Developing Advanced Broadband Microwave Detectors for Next-Generation CMB Polarization Studies

Data.gov (United States)

National Aeronautics and Space Administration — The photons of the cosmic microwave background (CMB) stream toward us from the boundary of the observable universe and arrive with information about both their point...

Probing the cosmological initial conditions using the CMB

Science.gov (United States)

Yadav, Amit P. S.

In the last few decades, advances in observational cosmology have given us a standard model of cosmology. The basic cosmological parameters have been laid out to high precision. Cosmologists have started asking questions about the nature of the cosmological initial conditions. Many ambitious experiments such as Planck satellite, EBEX, ACT, CAPMAP, QUaD, BICEP, SPIDER, QUIET, and GEM are underway. Experiments like these will provide us with a wealth of information about CMB polarization, CMB lensing, and polarization foregrounds. These experiments will be complemented with great observational campaigns to map the 3D structure in the Universe and new particle physics constraints from the Large Hadron Collider. In my graduate work I have made explicit how observations of the CMB temperature and E-polarization anisotropies can be combined to provide optimal constraints on models of the early universe at the highest energies. I have developed new ways of constraining models of the early universe using CMB temperature and polarization data. Inflation is one of the most promising theories of the early universe. Different inflationary models predict different amounts of non-Gaussian perturbations. Although any non-Gaussianity predicted by the canonical inflation model is very small, there exist models which can generate significant amounts of non-Gaussianities. Hence any characterization of non-Gaussianity of the primordial perturbations constrains the models of inflation. The information in the bispectrum (or higher order moments) is completely independent of the power spectrum constraints on the amplitude of primordial power spectrum (A), the scalar spectral index of the primordial power spectrum ns, and the running of the primordial power spectrum. My work has made it possible to extract the bispectrum information from large, high resolution CMB temperature and polarization data. We have demonstrated that the primordial adiabatic perturbations can be reconstructed using

Power filtration of CMB observational data

DEFF Research Database (Denmark)

Novikov, D.I.; Naselsky, P.; Jørgensen, H.E.

2001-01-01

We propose a power filter Cp for linear reconstruction of the CMB signal from one-dimensional scans of observational maps. This Gp filter preserves the power spectrum of the CMB signal in contrast to the Wiener filter which diminishes the power spectrum of the reconstructed CMB signal. We demonst...

Detection of CMB lensing in Planck-HFI data

International Nuclear Information System (INIS)

Lavabre, Alexis

2011-01-01

The Planck satellite is the third generation experiment dedicated to the observation of the cosmic microwave background (CMB). The resolution and sensibility of its instruments allow for the first time the detection of the weak lensing effect on CMB. This thesis present a original detection method of this effect in the data of the HFI instrument of Planck.The first part give a general description of the standard model of cosmology et the physics of the CMB. The part then presents the details of the weak lensing effect, concentrating on its impact on the CMB observables. This part ends with a description of the Planck satellite and its instruments.The second part, describes the set of simulations and analysis tools that I have developed allowing me to make the first measurement of the weak lensing effect on CMB. It presents the original method that I used which is based on a patch analysis of the full sky data, that is able to only take into account the less contaminated regions. This part also present the characterisation of the lensing potential estimator for masked maps in the presence of inhomogeneous noise and introduce a method, based on Monte-Carlo simulations, that is used to correct for the bias produced by the analysis method.The last part, concentrates on the work on HFI data. The first chapter presents the application of the above method to the maps of the combined observations at 143 GHz and 217 GHz and the maps from component separation using GMCA algorithm. The results show a deflection power spectrum compatible with the one expect in a lambda CMB universe, calculated with the cosmological parameters estimated by WMAP including seven years of observations. Using the points, from the combined estimation from the 143 GHz and 217 GHz maps, for multipole smaller than 500, gives a 1.26 Chi2 by degree of freedom. Finally, the last chapter presents the compression algorithm used onboard to compression HFI data. It gives the details of the tuning and the

Optimization study for the experimental configuration of CMB-S4

Science.gov (United States)

Barron, Darcy; Chinone, Yuji; Kusaka, Akito; Borril, Julian; Errard, Josquin; Feeney, Stephen; Ferraro, Simone; Keskitalo, Reijo; Lee, Adrian T.; Roe, Natalie A.; Sherwin, Blake D.; Suzuki, Aritoki

2018-02-01

The CMB Stage 4 (CMB-S4) experiment is a next-generation, ground-based experiment that will measure the cosmic microwave background (CMB) polarization to unprecedented accuracy, probing the signature of inflation, the nature of cosmic neutrinos, relativistic thermal relics in the early universe, and the evolution of the universe. CMB-S4 will consist of O(500,000) photon-noise-limited detectors that cover a wide range of angular scales in order to probe the cosmological signatures from both the early and late universe. It will measure a wide range of microwave frequencies to cleanly separate the CMB signals from galactic and extra-galactic foregrounds. To advance the progress towards designing the instrument for CMB-S4, we have established a framework to optimize the instrumental configuration to maximize its scientific output. The framework combines cost and instrumental models with a cosmology forecasting tool, and evaluates the scientific sensitivity as a function of various instrumental parameters. The cost model also allows us to perform the analysis under a fixed-cost constraint, optimizing for the scientific output of the experiment given finite resources. In this paper, we report our first results from this framework, using simplified instrumental and cost models. We have primarily studied two classes of instrumental configurations: arrays of large-aperture telescopes with diameters ranging from 2–10 m, and hybrid arrays that combine small-aperture telescopes (0.5-m diameter) with large-aperture telescopes. We explore performance as a function of telescope aperture size, distribution of the detectors into different microwave frequencies, survey strategy and survey area, low-frequency noise performance, and balance between small and large aperture telescopes for hybrid configurations. Both types of configurations must cover both large (~ degree) and small (~ arcmin) angular scales, and the performance depends on assumptions for performance vs. angular scale

Cross-correlation studies between CMB temperature anisotropies and 21 cm fluctuations

International Nuclear Information System (INIS)

Cooray, Asantha

2004-01-01

During the transition from a neutral to a fully reionized universe, scattering of cosmic microwave background (CMB) photons via free electrons leads to a new anisotropy contribution to the temperature distribution. If the reionization process is inhomogeneous and patchy, the era of reionization is also visible via brightness temperature fluctuations in the redshifted 21 cm line emission from neutral hydrogen. Since regions containing electrons and neutral hydrogen are expected to trace the same underlying density field, the two are (anti)correlated and this is expected to be reflected in the anisotropy maps via a correlation between arcminute-scale CMB temperature and the 21 cm background. In terms of the angular cross-power spectrum, unfortunately, this correlation is insignificant due to a geometric cancellation associated with second-order CMB anisotropies. The same cross correlation between ionized and neutral regions, however, can be studied using a bispectrum involving large-scale velocity field of ionized regions from the Doppler effect, arcminute-scale CMB anisotropies during reionization, and the 21 cm background. While the geometric cancellation is partly avoided, the signal-to-noise ratio related to this bispectrum is reduced due to the large cosmic variance related to velocity fluctuations traced by the Doppler effect. Unless the velocity field during reionization can be independently established, it is unlikely that the correlation information related to the relative distribution of ionized electrons and regions containing neutral hydrogen can be obtained with a combined study involving CMB and 21 cm fluctuations

Advanced Antenna-Coupled Superconducting Detector Arrays for CMB Polarimetry

Science.gov (United States)

Bock, James

2014-01-01

We are developing high-sensitivity millimeter-wave detector arrays for measuring the polarization of the cosmic microwave background (CMB). This development is directed to advance the technology readiness of the Inflation Probe mission in NASA's Physics of the Cosmos program. The Inflation Probe is a fourth-generation CMB satellite that will measure the polarization of the CMB to astrophysical limits, characterizing the inflationary polarization signal, mapping large-scale structure based on polarization induced by gravitational lensing, and mapping Galactic magnetic fields through measurements of polarized dust emission. The inflationary polarization signal is produced by a background of gravitational waves from the epoch of inflation, an exponential expansion of space-time in the early universe, with an amplitude that depends on the physical mechanism producing inflation. The inflationary polarization signal may be distinguished by its unique 'B-mode' vector properties from polarization from the density variations that predominantly source CMB temperature anisotropy. Mission concepts for the Inflation Probe are being developed in the US, Europe and Japan. The arrays are based on planar antennas that provide integral beam collimation, polarization analysis, and spectral band definition in a compact lithographed format that eliminates discrete fore-optics such as lenses and feedhorns. The antennas are coupled to transition-edge superconducting bolometers, read out with multiplexed SQUID current amplifiers. The superconducting sensors and readouts developed in this program share common technologies with NASA X-ray and FIR detector applications. Our program targets developments required for space observations, and we discuss our technical progress over the past two years and plans for future development. We are incorporating arrays into active sub-orbital and ground-based experiments, which advance technology readiness while producing state of the art CMB

Reionization history and CMB parameter estimation

International Nuclear Information System (INIS)

Dizgah, Azadeh Moradinezhad; Kinney, William H.; Gnedin, Nickolay Y.

2013-01-01

We study how uncertainty in the reionization history of the universe affects estimates of other cosmological parameters from the Cosmic Microwave Background. We analyze WMAP7 data and synthetic Planck-quality data generated using a realistic scenario for the reionization history of the universe obtained from high-resolution numerical simulation. We perform parameter estimation using a simple sudden reionization approximation, and using the Principal Component Analysis (PCA) technique proposed by Mortonson and Hu. We reach two main conclusions: (1) Adopting a simple sudden reionization model does not introduce measurable bias into values for other parameters, indicating that detailed modeling of reionization is not necessary for the purpose of parameter estimation from future CMB data sets such as Planck. (2) PCA analysis does not allow accurate reconstruction of the actual reionization history of the universe in a realistic case

Reionization history and CMB parameter estimation

Energy Technology Data Exchange (ETDEWEB)

Dizgah, Azadeh Moradinezhad; Gnedin, Nickolay Y.; Kinney, William H.

2013-05-01

We study how uncertainty in the reionization history of the universe affects estimates of other cosmological parameters from the Cosmic Microwave Background. We analyze WMAP7 data and synthetic Planck-quality data generated using a realistic scenario for the reionization history of the universe obtained from high-resolution numerical simulation. We perform parameter estimation using a simple sudden reionization approximation, and using the Principal Component Analysis (PCA) technique proposed by Mortonson and Hu. We reach two main conclusions: (1) Adopting a simple sudden reionization model does not introduce measurable bias into values for other parameters, indicating that detailed modeling of reionization is not necessary for the purpose of parameter estimation from future CMB data sets such as Planck. (2) PCA analysis does not allow accurate reconstruction of the actual reionization history of the universe in a realistic case.

Searching for a holographic connection between dark energy and the low-l CMB multipoles

DEFF Research Database (Denmark)

Enqvist, Kari; Hannestad, Steen; Sloth, Martin Snoager

2004-01-01

We consider the angular power spectrum in a finite universe with different boundary conditions and perform a fit to the CMB, LSS and supernova data. A finite universe could be the consequence of a holographic constraint, giving rise to an effective IR cutoff at the future event horizon...

Large-Scale Corrections to the CMB Anisotropy from Asymptotic de Sitter Mode

Science.gov (United States)

Sojasi, A.

2018-01-01

In this study, large-scale effects from asymptotic de Sitter mode on the CMB anisotropy are investigated. Besides the slow variation of the Hubble parameter onset of the last stage of inflation, the recent observational constraints from Planck and WMAP on spectral index confirm that the geometry of the universe can not be pure de Sitter in this era. Motivated by these evidences, we use this mode to calculate the power spectrum of the CMB anisotropy on the large scale. It is found that the CMB spectrum is dependent on the index of Hankel function ν which in the de Sitter limit ν → 3/2, the power spectrum reduces to the scale invariant result. Also, the result shows that the spectrum of anisotropy is dependent on angular scale and slow-roll parameter and these additional corrections are swept away by a cutoff scale parameter H ≪ M ∗ < M P .

Creation of the CMB spectrum: precise analytic solutions for the blackbody photosphere

Energy Technology Data Exchange (ETDEWEB)

Khatri, Rishi; Sunyaev, Rashid A., E-mail: khatri@mpa-garching.mpg.de, E-mail: sunyaev@mpa-Garching.mpg.de [Max Planck Institut für Astrophysik, Karl-Schwarzschild-Str. 1, 85741 Garching (Germany)

2012-06-01

The blackbody spectrum of CMB was created in the blackbody photosphere at redshifts z∼>2 × 10{sup 6}. At these early times, the Universe was dense and hot enough that complete thermal equilibrium between baryonic matter (electrons and ions) and photons could be established on time scales much shorter than the age of the Universe. Any perturbation away from the blackbody spectrum was suppressed exponentially. New physics, for example annihilation and decay of dark matter, can add energy and photons to CMB at redshifts z∼>10{sup 5} and result in a Bose-Einstein spectrum with a non-zero chemical potential (μ). Precise evolution of the CMB spectrum around the critical redshift of z ≅ 2 × 10{sup 6} is required in order to calculate the μ-type spectral distortion and constrain the underlying new physics. Although numerical calculation of important processes involved (double Compton process, comptonization and bremsstrahlung) is not difficult with present day computers, analytic solutions are much faster and easier to calculate and provide valuable physical insights. We provide precise (better than 1%) analytic solutions for the decay of μ, created at an earlier epoch, including all three processes, double Compton, Compton scattering on thermal electrons and bremsstrahlung in the limit of small distortions. This is a significant improvement over the existing solutions with accuracy ∼ 10% or worse. We also give a census of important sources of energy injection into CMB in standard cosmology. In particular, calculations of distortions from electron-positron annihilation and primordial nucleosynthesis illustrate in a dramatic way the strength of the equilibrium restoring processes in the early Universe. Finally, we point out the triple degeneracy in standard cosmology, i.e., the μ and y distortions from adiabatic cooling of baryons and electrons, Silk damping and annihilation of thermally produced WIMP dark matter are of similar order of magnitude ( ∼ 10{sup

Conformal Invariance, Dark Energy, and CMB Non-Gaussianity

CERN Document Server

Antoniadis, Ignatios; Mottola, Emil

2012-01-01

We show that in addition to simple scale invariance, a universe dominated by dark energy naturally gives rise to correlation functions possessing full conformal invariance. This is due to the mathematical isomorphism between the conformal group of certain three dimensional slices of de Sitter space and the de Sitter isometry group SO(4,1). In the standard homogeneous, isotropic cosmological model in which primordial density perturbations are generated during a long vacuum energy dominated de Sitter phase, the embedding of flat spatial R^3 sections in de Sitter space induces a conformal invariant perturbation spectrum and definite prediction for the shape of the non-Gaussian CMB bispectrum. In the case in which the density fluctuations are generated instead on the de Sitter horizon, conformal invariance of the S^2 horizon embedding implies a different but also quite definite prediction for the angular correlations of CMB non-Gaussianity on the sky. Each of these forms for the bispectrum is intrinsic to the sym...

Observational constraint on spherical inhomogeneity with CMB and local Hubble parameter

Science.gov (United States)

Tokutake, Masato; Ichiki, Kiyotomo; Yoo, Chul-Moon

2018-03-01

We derive an observational constraint on a spherical inhomogeneity of the void centered at our position from the angular power spectrum of the cosmic microwave background (CMB) and local measurements of the Hubble parameter. The late time behaviour of the void is assumed to be well described by the so-called Λ-Lemaȋtre-Tolman-Bondi (ΛLTB) solution. Then, we restrict the models to the asymptotically homogeneous models each of which is approximated by a flat Friedmann-Lemaȋtre-Robertson-Walker model. The late time ΛLTB models are parametrized by four parameters including the value of the cosmological constant and the local Hubble parameter. The other two parameters are used to parametrize the observed distance-redshift relation. Then, the ΛLTB models are constructed so that they are compatible with the given distance-redshift relation. Including conventional parameters for the CMB analysis, we characterize our models by seven parameters in total. The local Hubble measurements are reflected in the prior distribution of the local Hubble parameter. As a result of a Markov-Chains-Monte-Carlo analysis for the CMB temperature and polarization anisotropies, we found that the inhomogeneous universe models with vanishing cosmological constant are ruled out as is expected. However, a significant under-density around us is still compatible with the angular power spectrum of CMB and the local Hubble parameter.

Future CMB cosmological constraints in a dark coupled universe

CERN Document Server

Martinelli, Matteo; Melchiorri, Alessandro; Mena, Olga

2010-01-01

Cosmic Microwave Background satellite missions as the on-going Planck experiment are expected to provide the strongest constraints on a wide set of cosmological parameters. Those constraints, however, could be weakened when the assumption of a cosmological constant as the dark energy component is removed. Here we show that it will indeed be the case when there exists a coupling among the dark energy and the dark matter fluids. In particular, the expected errors on key parameters as the cold dark matter density and the angular diameter distance at decoupling are significantly larger when a dark coupling is introduced. We show that it will be the case also for future satellite missions as EPIC, unless CMB lensing extraction is performed.

Novel calibration system with sparse wires for CMB polarization receivers

International Nuclear Information System (INIS)

Tajima, O.; Nguyen, H.; Bischoff, C.; Brizius, A.; Buder, I.; Kusaka, A.

2011-01-01

B-modes in the cosmic microwave background (CMB) polarization is a smoking gun signature of the inflationary universe. To achieve better sensitivity to this faint signal, CMB polarization experiments aim to maximize the number of detector elements, resulting in a large focal plane receiver. Detector calibration of the polarization response becomes essential. It is extremely useful to be able to calibrate 'simultaneously' all detectors on the large focal plane. We developed a novel calibration system that rotates a large 'sparse' grid of metal wires, in front of and fully covering the field of view of the focal plane receiver. Polarized radiation is created via the reflection of ambient temperature from the wire surface. Since the detector has a finite beam size, the observed signal is smeared according to the beam property. The resulting smeared polarized radiation has a reasonable intensity (a few Kelvin or less) compared to the sky temperature (∼10 K observing condition). The system played a successful role for receiver calibration of QUIET, a CMB polarization experiment located in the Atacama desert in Chile. The successful performance revealed that this system is applicable to other experiments based on different technologies, e.g. TES bolometers.

Probing the BSM physics with CMB precision cosmology: an application to supersymmetry

Science.gov (United States)

Dalianis, Ioannis; Watanabe, Yuki

2018-02-01

The cosmic history before the BBN is highly determined by the physics that operates beyond the Standard Model (BSM) of particle physics and it is poorly constrained observationally. Ongoing and future precision measurements of the CMB observables can provide us with significant information about the pre-BBN era and hence possibly test the cosmological predictions of different BSM scenarios. Supersymmetry is a particularly motivated BSM theory and it is often the case that different superymmetry breaking schemes require different cosmic histories with specific reheating temperatures or low entropy production in order to be cosmologically viable. In this paper we quantify the effects of the possible alternative cosmic histories on the n s and r CMB observables assuming a generic non-thermal stage after cosmic inflation. We analyze TeV and especially multi-TeV super-symmetry breaking schemes assuming the neutralino and gravitino dark matter scenarios. We complement our analysis considering the Starobinsky R 2 inflation model to exemplify the improved CMB predictions that a unified description of the early universe cosmic evolution yields. Our analysis underlines the importance of the CMB precision measurements that can be viewed, to some extend, as complementary to the laboratory experimental searches for supersymmetry or other BSM theories.

Searching for primordial non-Gaussianity in Planck CMB maps using a combined estimator

Energy Technology Data Exchange (ETDEWEB)

Novaes, C.P.; Wuensche, C.A. [Divisão de Astrofísica, Instituto Nacional de Pesquisas Espaciais, Av. dos Astronautas 1758, São José dos Campos 12227-010, SP (Brazil); Bernui, A. [Observatório Nacional, Rua General José Cristino 77, São Cristóvão, 20921-400, Rio de Janeiro, RJ (Brazil); Ferreira, I.S., E-mail: camilapnovaes@gmail.com, E-mail: bernui@on.br, E-mail: ivan@fis.unb.br, E-mail: ca.wuensche@inpe.br [Instituto de Física, Universidade de Brasília, Campus Universitário Darcy Ribeiro, Asa Norte, 70919-970, Brasília, DF (Brazil)

2014-01-01

The extensive search for deviations from Gaussianity in cosmic microwave background radiation (CMB) data is very important due to the information about the very early moments of the universe encoded there. Recent analyses from Planck CMB data do not exclude the presence of non-Gaussianity of small amplitude, although they are consistent with the Gaussian hypothesis. The use of different techniques is essential to provide information about types and amplitudes of non-Gaussianities in the CMB data. In particular, we find interesting to construct an estimator based upon the combination of two powerful statistical tools that appears to be sensitive enough to detect tiny deviations from Gaussianity in CMB maps. This estimator combines the Minkowski functionals with a Neural Network, maximizing a tool widely used to study non-Gaussian signals with a reinforcement of another tool designed to identify patterns in a data set. We test our estimator by analyzing simulated CMB maps contaminated with different amounts of local primordial non-Gaussianity quantified by the dimensionless parameter f{sub  NL}. We apply it to these sets of CMB maps and find ∼> 98% of chance of positive detection, even for small intensity local non-Gaussianity like f{sub  NL} = 38±18, the current limit from Planck data for large angular scales. Additionally, we test the suitability to distinguish between primary and secondary non-Gaussianities: first we train the Neural Network with two sets, one of nearly Gaussian CMB maps (|f{sub  NL}| ≤ 10) but contaminated with realistic inhomogeneous Planck noise (i.e., secondary non-Gaussianity) and the other of non-Gaussian CMB maps, that is, maps endowed with weak primordial non-Gaussianity (28 ≤ f{sub  NL} ≤ 48); after that we test an ensemble composed of CMB maps either with one of these non-Gaussian contaminations, and find out that our method successfully classifies ∼ 95% of the tested maps as being CMB maps containing primordial or

Transformation of the angular power spectrum of the Cosmic Microwave Background (CMB) radiation into reciprocal spaces and consequences of this approach

Czech Academy of Sciences Publication Activity Database

Červinka, Ladislav

2011-01-01

Roč. 2, č. 11 (2011), s. 1331-1347 ISSN 2153-120X Institutional research plan: CEZ:AV0Z10100521 Keywords : CMB radiation * analysis of CMB spectrum * radial distribution function of objects * early universe cluster structure * density of ordinary matter Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics

Dynamical 3-Space Predicts Hotter Early Universe: Resolves CMB-BBN 7-Li and 4-He Abundance Anomalies

Directory of Open Access Journals (Sweden)

Cahill R. T.

2010-01-01

Full Text Available The observed abundances of 7-Li and 4-He are significantly inconsistent with the predictions from Big Bang Nucleosynthesis (BBN when using the $Lambda$CDM cosmological model together with the value for $Omega_B h^2 = 0.0224pm0.0009$ from WMAP CMB fluctuations, with the value from BBN required to fit observed abundances being $0.009 < Omega_B h^2 < 0.013$. The dynamical 3-space theory is shown to predict a 20% hotter universe in the radiation-dominated epoch, which then results in a remarkable parameter-free agreement between the BBN and the WMAP value for $Omega_B h^2$. The dynamical 3-space also gives a parameter-free fit to the supernova redshift data, and predicts that the flawed $Lambda$CDM model would require $Omega_Lambda = 0.73$ and $Omega_M = 0.27$ to fit the 3-space dynamics Hubble expansion, and independently of the supernova data. These results amount to the discovery of new physics for the early universe that is matched by numerous other successful observational and experimental tests.

Dynamical 3-Space Predicts Hotter Early Universe: Resolves CMB-BBN 7-Li and 4-He Abundance Anomalies

Directory of Open Access Journals (Sweden)

Cahill R. T.

2010-01-01

Full Text Available The observed abundances of 7 Li and 4 He are significantly inconsistent with the pre- dictions from Big Bang Nucleosynthesis (BBN when using the CDM cosmolog- ical model together with the value for B h 2 = 0 : 0224 0 : 0009 from WMAP CMB fluctuations, with the value from BBN required to fit observed abundances being 0 : 009 < B h 2 < 0 : 013. The dynamical 3-space theory is shown to predict a 20% hot- ter universe in the radiation-dominated epoch, which then results in a remarkable parameter-free agreement between the BBN and the WMAP value for B h 2 . The dy- namical 3-space also gives a parameter-free fit to the supernova redshift data, and pre- dicts that the flawed CDM model would require = 0 : 73 and M = 0 : 27 to fit the 3-space dynamics Hubble expansion, and independently of the supernova data. These results amount to the discovery of new physics for the early universe that is matched by numerous other successful observational and experimental tests.

Novel calibration system with sparse wires for CMB polarization receivers

Energy Technology Data Exchange (ETDEWEB)

Tajima, O.; /KEK, Tsukuba /Chicago U., KICP; Nguyen, H.; /Fermilab; Bischoff, C.; /Chicago U., KICP /Harvard-Smithsonian Ctr. Astrophys.; Brizius, A.; Buder, I.; Kusaka, A. /Chicago U., KICP

2011-07-01

B-modes in the cosmic microwave background (CMB) polarization is a smoking gun signature of the inflationary universe. To achieve better sensitivity to this faint signal, CMB polarization experiments aim to maximize the number of detector elements, resulting in a large focal plane receiver. Detector calibration of the polarization response becomes essential. It is extremely useful to be able to calibrate 'simultaneously' all detectors on the large focal plane. We developed a novel calibration system that rotates a large 'sparse' grid of metal wires, in front of and fully covering the field of view of the focal plane receiver. Polarized radiation is created via the reflection of ambient temperature from the wire surface. Since the detector has a finite beam size, the observed signal is smeared according to the beam property. The resulting smeared polarized radiation has a reasonable intensity (a few Kelvin or less) compared to the sky temperature ({approx}10 K observing condition). The system played a successful role for receiver calibration of QUIET, a CMB polarization experiment located in the Atacama desert in Chile. The successful performance revealed that this system is applicable to other experiments based on different technologies, e.g. TES bolometers.

Recent development in CMB experiments

International Nuclear Information System (INIS)

Matsumura, T.

2014-01-01

The rich data from the measurements of the cosmic microwave background (CMB) have played a key role to establish the ΛCDM cosmology. The WMAP results combined with Type Ia Supernova and BAO constrain not only the standard cosmological parameters to a few percent level. The combination of the data such as WMAP, SPT and H 0 started constraining such as the cosmic inflation r ν <0.38, and the equation of the dark energy w=-1.087 ± 0.096. The current experimental efforts are focused to measure the CMB B-mode polarization to probe deeper to 'beyond standard model' parameters from the sky. The upcoming ground-base and balloon-borne experiments are designed for r∼0.01. This sensitivity with an arcmin scale angular resolution is also well within the detection of the lensing B-mode. I review the recent development and the prospect from the upcoming CMB experiments. (author)

Can CMB Surveys Help the AGN Community?

Directory of Open Access Journals (Sweden)

Bruce Partridge

2017-08-01

Full Text Available Contemporary projects to measure anisotropies in the cosmic microwave background (CMB are now detecting hundreds to thousands of extragalactic radio sources, most of them blazars. As a member of a group of CMB scientists involved in the construction of catalogues of such sources and their analysis, I wish to point out the potential value of CMB surveys to studies of AGN jets and their polarization. Current CMB projects, for instance, reach mJy sensitivity, offer wide sky coverage, are “blind” and generally of uniform sensitivity across the sky (hence useful statistically, make essentially simultaneous multi-frequency observations at frequencies from 30 to 857 GHz, routinely offer repeated observations of sources with interesting cadences and now generally provide polarization measurements. The aim here is not to analyze in any depth the AGN science already derived from such projects, but rather to heighten awareness of their promise for the AGN community.

Observing patchy reionization with future CMB polarization experiments

Science.gov (United States)

Roy, A.; Lapi, A.; Spergel, D.; Baccigalupi, C.

2018-05-01

We study the signal from patchy reionization in view of the future high accuracy polarization measurements of the Cosmic Microwave Background (CMB). We implement an extraction procedure of the patchy reionization signal analogous to CMB lensing. We evaluate the signal to noise ratio (SNR) for the future Stage IV (S4) CMB experiment. The signal has a broad peak centered on the degree angular scales, with a long tail at higher multipoles. The CMB S4 experiment can effectively constrain the properties of reionization by measuring the signal on degree scales. The signal amplitude depends on the properties of the structure determining the reionization morphology. We describe bubbles having radii distributed log-normally. The expected S/N is sensitive to the mean bubble radius: bar R=5 Mpc implies S/N ≈ 4, bar R=10 Mpc implies S/N ≈ 20. The spread of the radii distribution strongly affects the integrated SNR, that changes by a factor of 102 when σlnr goes from ln 2 to ln 3. Future CMB experiments will thus place important constraints on the physics of reionization.

5,120 Superconducting Bolometers for the PIPER Balloon-Borne CMB Polarization Experiment

Science.gov (United States)

Benford, Dominic J.; Chuss, David T.; Hilton, Gene C.; Irwin, Kent D.; Jethava, Nikhil S.; Jhabvala, Christine A.; Kogut, Alan J.; Miller, Timothy M.; Mirel, Paul; Moseley, S. Harvey;

Foreground removal from CMB temperature maps using an MLP neural network

DEFF Research Database (Denmark)

Nørgaard-Nielsen, Hans Ulrik; Jørgensen, H.E.

2008-01-01

the CMB temperature signal from the combined signal CMB and the foregrounds has been investigated. As a specific example, we have analysed simulated data, as expected from the ESA Planck CMB mission. A simple multilayer perceptron neural network with 2 hidden layers can provide temperature estimates over...... CMB signal it is essential to minimize the systematic errors in the CMB temperature determinations. Following the available knowledge of the spectral behavior of the Galactic foregrounds simple power law-like spectra have been assumed. The feasibility of using a simple neural network for extracting...

CMB anisotropies interpolation

NARCIS (Netherlands)

Zinger, S.; Delabrouille, Jacques; Roux, Michel; Maitre, Henri

2010-01-01

We consider the problem of the interpolation of irregularly spaced spatial data, applied to observation of Cosmic Microwave Background (CMB) anisotropies. The well-known interpolation methods and kriging are compared to the binning method which serves as a reference approach. We analyse kriging

Evidence for an inflationary phase transition from the LSS and CMB anisotropy data

International Nuclear Information System (INIS)

Barriga, J.; Gaztanaga, E.; Santos, M.G.; Sarkar, S.

2001-01-01

In the light of the recent Boomerang and Maxima observations of the CMB which show an anomalously low second acoustic peak, we reexamine the prediction by Adams et al (1997) that this would be the consequence of a 'step' in the primordial spectrum induced by a spontaneous symmetry breaking phase transition during primordial inflation. We demonstrate that a deviation from scale-invariance around k ∼ 0.1h Mpc -1 can simultaneously explain both the feature identified earlier in the APM galaxy power spectrum as well the recent CMB anisotropy data, with a baryon density consistent with the BBN value. Such a break also allows a good fit to the data on cluster abundances even for a critical density matter-dominated universe with zero cosmological constant

Gravitational lensing of the CMB: A Feynman diagram approach

Directory of Open Access Journals (Sweden)

Elizabeth E. Jenkins

2014-09-01

Full Text Available We develop a Feynman diagram approach to calculating correlations of the Cosmic Microwave Background (CMB in the presence of distortions. As one application, we focus on CMB distortions due to gravitational lensing by Large Scale Structure (LSS. We study the Hu–Okamoto quadratic estimator for extracting lensing from the CMB and derive the noise of the estimator up to O(ϕ4 in the lensing potential ϕ. By identifying the diagrams responsible for the previously noted large O(ϕ4 term, we conclude that the lensing expansion does not break down. The convergence can be significantly improved by a reorganization of the ϕ expansion. Our approach makes it simple to obtain expressions for quadratic estimators based on any CMB channel, including many previously unexplored cases. We briefly discuss other applications to cosmology of this diagrammatic approach, such as distortions of the CMB due to patchy reionization, or due to Faraday rotation from primordial axion fields.

Experiments on the CMB Spectrum, Big Jets Model and Their Implications for the Missing Half of the Universe

Directory of Open Access Journals (Sweden)

Hsu Leonardo

2018-01-01

Full Text Available Based on the limiting continuation of Lorentz-Poincaré invariance, we propose an alternative formulation of the generalized Planck distribution for inertial and noninertial frames. The Lorentz invariant Planck distribution law leads to a new physical interpretation of the dipole anisotropy of the Cosmic Microwave Background. The Big Jets model predicts a distant ‘antimatter blackbody,’ whose radiations could make 50% of the sky very slightly warmer than the isotropic CMB temperature TCMB with a cosine function. The other 50% of the sky has the same isotropic temperature TCMB. Thus, we could have a pseudo-dipole anisotropy because the microwaves emitted from the antimatter blackbody are totally absorbed by our matter blackbody. We suggest that accurate data of satellite experiments might be used to search for the pseudo-dipole anisotropy and the missing half of the antimatter universe.

CMB constraints on running non-Gaussianity

OpenAIRE

Oppizzi, Filippo; Liguori, Michele; Renzi, Alessandro; Arroja, Frederico; Bartolo, Nicola

2017-01-01

We develop a complete set of tools for CMB forecasting, simulation and estimation of primordial running bispectra, arising from a variety of curvaton and single-field (DBI) models of Inflation. We validate our pipeline using mock CMB running non-Gaussianity realizations and test it on real data by obtaining experimental constraints on the $f_{\\rm NL}$ running spectral index, $n_{\\rm NG}$, using WMAP 9-year data. Our final bounds (68\\% C.L.) read $-0.3< n_{\\rm NG}

Cosmological constraint on the light gravitino mass from CMB lensing and cosmic shear

Energy Technology Data Exchange (ETDEWEB)

Osato, Ken; Yoshida, Naoki [Department of Physics, School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo, Tokyo, 113-0033 (Japan); Sekiguchi, Toyokazu [University of Helsinki and Helsinki Institute of Physics, P.O. Box 64, FI-00014, Helsinki (Finland); Shirasaki, Masato [National Astronomical Observatory of Japan, Mitaka, Tokyo, 181-8588 (Japan); Kamada, Ayuki, E-mail: ken.osato@utap.phys.s.u-tokyo.ac.jp, E-mail: toyokazu.sekiguchi@gmail.com, E-mail: masato.shirasaki@nao.ac.jp, E-mail: ayuki.kamada@ucr.edu, E-mail: naoki.yoshida@phys.s.u-tokyo.ac.jp [Department of Physics and Astronomy, University of California, Riverside, California 92521 (United States)

2016-06-01

Light gravitinos of mass ∼< O (10) eV are of particular interest in cosmology, offering various baryogenesis scenarios without suffering from the cosmological gravitino problem. The gravitino may contribute considerably to the total matter content of the Universe and affect structure formation from early to present epochs. After the gravitinos decouple from other particles in the early Universe, they free-stream and consequently suppress density fluctuations of (sub-)galactic length scales. Observations of structure at the relevant length-scales can be used to infer or constrain the mass and the abundance of light gravitinos. We derive constraints on the light gravitino mass using the data of cosmic microwave background (CMB) lensing from Planck and of cosmic shear from the Canada France Hawaii Lensing Survey survey, combined with analyses of the primary CMB anisotropies and the signature of baryon acoustic oscillations in galaxy distributions. The obtained constraint on the gravitino mass is m {sub 3/2} < 4.7 eV (95 % C.L.), which is substantially tighter than the previous constraint from clustering analysis of Ly-α forests.

Evidence for an inflationary phase transition from the LSS and CMB anisotropy data

Energy Technology Data Exchange (ETDEWEB)

Barriga, J.; Gaztanaga, E.; Santos, M.G.; Sarkar, S

2001-04-01

In the light of the recent Boomerang and Maxima observations of the CMB which show an anomalously low second acoustic peak, we reexamine the prediction by Adams et al (1997) that this would be the consequence of a 'step' in the primordial spectrum induced by a spontaneous symmetry breaking phase transition during primordial inflation. We demonstrate that a deviation from scale-invariance around k {approx} 0.1h Mpc{sup -1} can simultaneously explain both the feature identified earlier in the APM galaxy power spectrum as well the recent CMB anisotropy data, with a baryon density consistent with the BBN value. Such a break also allows a good fit to the data on cluster abundances even for a critical density matter-dominated universe with zero cosmological constant.

Multiverse effects on the CMB angular correlation function in the framework of NCG

Science.gov (United States)

Arabzadeh, Sahar; Kaviani, Kamran

Following many theories that predict the existence of the multiverse and by conjecture that our space-time may have a generalized geometrical structure at the fundamental level, we are interested in using a non-commutative geometry (NCG) formalism to study a suggested two-layer space that contains our 4-dimensional (4D) universe and a re-derived photon propagator. It can be shown that the photon propagator and a cosmic microwave background (CMB) angular correlation function are comparable, and if there exists such a multiverse system, the distance between the two layers can be estimated to be within the observable universe’s radius. Furthermore, this study revealed that our results are not limited to CMB but can be applied to many other types of radiation, such as X-rays.

Primordial gravitational waves measurements and anisotropies of CMB polarization rotation

Directory of Open Access Journals (Sweden)

Si-Yu Li

2015-12-01

Full Text Available Searching for the signal of primordial gravitational waves in the B-modes (BB power spectrum is one of the key scientific aims of the cosmic microwave background (CMB polarization experiments. However, this could be easily contaminated by several foreground issues, such as the interstellar dust grains and the galactic cyclotron electrons. In this paper we study another mechanism, the cosmic birefringence, which can be introduced by a CPT-violating interaction between CMB photons and an external scalar field. Such kind of interaction could give rise to the rotation of the linear polarization state of CMB photons, and consequently induce the CMB BB power spectrum, which could mimic the signal of primordial gravitational waves at large scales. With the recently released polarization data of BICEP2 and the joint analysis data of BICEP2/Keck Array and Planck, we perform a global fitting analysis on constraining the tensor-to-scalar ratio r by considering the polarization rotation angle [α(nˆ] which can be separated into a background isotropic part [α¯] and a small anisotropic part [Δα(nˆ]. Since the data of BICEP2 and Keck Array experiments have already been corrected by using the “self-calibration” method, here we mainly focus on the effects from the anisotropies of CMB polarization rotation angle. We find that including Δα(nˆ in the analysis could slightly weaken the constraints on the tensor-to-scalar ratio r, when using current CMB polarization measurements. We also simulate the mock CMB data with the BICEP3-like sensitivity. Very interestingly, we find that if the effects of the anisotropic polarization rotation angle could not be taken into account properly in the analysis, the constraints on r will be dramatically biased. This implies that we need to break the degeneracy between the anisotropies of the CMB polarization rotation angle and the CMB primordial tensor perturbations, in order to measure the signal of primordial

Cosmological CPT violation and CMB polarization measurements

Energy Technology Data Exchange (ETDEWEB)

Xia, Jun-Qing, E-mail: xia@sissa.it [Scuola Internazionale Superiore di Studi Avanzati, Via Bonomea 265, I-34136 Trieste (Italy)

2012-01-01

In this paper we study the possibility of testing Charge-Parity-Time Reversal (CPT) symmetry with cosmic microwave background (CMB) experiments. We consider two kinds of Chern-Simons (CS) term, electromagnetic CS term and gravitational CS term, and study their effects on the CMB polarization power spectra in detail. By combining current CMB polarization measurements, the seven-year WMAP, BOOMERanG 2003 and BICEP observations, we obtain a tight constraint on the rotation angle Δα = −2.28±1.02 deg (1 σ), indicating a 2.2 σ detection of the CPT violation. Here, we particularly take the systematic errors of CMB measurements into account. After adding the QUaD polarization data, the constraint becomes −1.34 < Δα < 0.82 deg at 95% confidence level. When comparing with the effect of electromagnetic CS term, the gravitational CS term could only generate TB and EB power spectra with much smaller amplitude. Therefore, the induced parameter ε can not be constrained from the current polarization data. Furthermore, we study the capabilities of future CMB measurements, Planck and CMBPol, on the constraints of Δα and ε. We find that the constraint of Δα can be significantly improved by a factor of 15. Therefore, if this rotation angle effect can not be taken into account properly, the constraints of cosmological parameters will be biased obviously. For the gravitational CS term, the future Planck data still can not constrain ε very well, if the primordial tensor perturbations are small, r < 0.1. We need the more accurate CMBPol experiment to give better constraint on ε.

Preferred axis of CMB parity asymmetry in the masked maps

International Nuclear Information System (INIS)

Cheng, Cheng; Zhao, Wen; Huang, Qing-Guo; Santos, Larissa

2016-01-01

Both WMAP and Planck data show a significant odd-multipole preference in the large scales of the cosmic microwave background (CMB) temperature anisotropies. If this pattern originates from cosmological effects, then it can be considered a crucial clue for a violation in the cosmological principle. By defining various direction dependent statistics in the full-sky Planck 2015 maps (see, for instance, Naselsky et al. (2012); W. Zhao (2014)), we found that the CMB parity asymmetry has a preferred direction, which is independent of the choices of the statistics. In particular, this preferred axis is strongly aligned with those in the CMB quadrupole and octopole, as well as that in the CMB kinematic dipole, which hints to their non-cosmological origin. In realistic observations, the foreground residuals are inevitable, and should be properly masked out in order to avoid possible misinterpretation of the results. In this paper, we extend our previous analyses to the masked Planck 2015 data. By defining a similar direction dependent statistic in the masked map, we find a preferred direction of the CMB parity asymmetry, in which the axis also coincides with that found in the full-sky analysis. Therefore, our conclusions on the CMB parity violation and its directional properties are confirmed.

Preferred axis of CMB parity asymmetry in the masked maps

Energy Technology Data Exchange (ETDEWEB)

Cheng, Cheng [State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Science, Beijing 100190 (China); Zhao, Wen, E-mail: wzhao7@ustc.edu.cn [CAS Key Laboratory for Researches in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Chinese Academy of Sciences, Hefei, Anhui 230026 (China); Huang, Qing-Guo [State Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Science, Beijing 100190 (China); Santos, Larissa [CAS Key Laboratory for Researches in Galaxies and Cosmology, Department of Astronomy, University of Science and Technology of China, Chinese Academy of Sciences, Hefei, Anhui 230026 (China)

2016-06-10

Both WMAP and Planck data show a significant odd-multipole preference in the large scales of the cosmic microwave background (CMB) temperature anisotropies. If this pattern originates from cosmological effects, then it can be considered a crucial clue for a violation in the cosmological principle. By defining various direction dependent statistics in the full-sky Planck 2015 maps (see, for instance, Naselsky et al. (2012); W. Zhao (2014)), we found that the CMB parity asymmetry has a preferred direction, which is independent of the choices of the statistics. In particular, this preferred axis is strongly aligned with those in the CMB quadrupole and octopole, as well as that in the CMB kinematic dipole, which hints to their non-cosmological origin. In realistic observations, the foreground residuals are inevitable, and should be properly masked out in order to avoid possible misinterpretation of the results. In this paper, we extend our previous analyses to the masked Planck 2015 data. By defining a similar direction dependent statistic in the masked map, we find a preferred direction of the CMB parity asymmetry, in which the axis also coincides with that found in the full-sky analysis. Therefore, our conclusions on the CMB parity violation and its directional properties are confirmed.

Foreground removal from CMB temperature maps using an MLP neural network

Science.gov (United States)

Nørgaard-Nielsen, H. U.; Jørgensen, H. E.

2008-12-01

One of the main obstacles for extracting the Cosmic Microwave Background (CMB) signal from observations in the mm-submm range is the foreground contamination by emission from Galactic components: mainly synchrotron, free-free and thermal dust emission. Due to the statistical nature of the intrinsic CMB signal it is essential to minimize the systematic errors in the CMB temperature determinations. Following the available knowledge of the spectral behavior of the Galactic foregrounds simple power law-like spectra have been assumed. The feasibility of using a simple neural network for extracting the CMB temperature signal from the combined signal CMB and the foregrounds has been investigated. As a specific example, we have analysed simulated data, as expected from the ESA Planck CMB mission. A simple multilayer perceptron neural network with 2 hidden layers can provide temperature estimates over more than 80 per cent of the sky that are to a high degree uncorrelated with the foreground signals. A single network will be able to cover the dynamic range of the Planck noise level over the entire sky.

The Role of the CMB in Redshift Related Departures from the Gao–Solomon Relation

Energy Technology Data Exchange (ETDEWEB)

Tunnard, R.; Greve, T. R., E-mail: richard.tunnard.13@ucl.ac.uk [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

2017-11-01

A strong correlation between the far-IR and HCN(1−0) line luminosities, known as the Gao–Solomon relation, has been observed to hold over more than 10 orders of magnitude in the local universe. Departures from this relation at redshifts ≳1.5 have been interpreted as evidence for increased dense gas star formation efficiency in luminous galaxies during the period of peak of star formation in the history of the universe. We examine whether the offsets from the relation can be explained by the hotter Cosmic Microwave Background (CMB) at high redshift, which, due to a loss of contrast against the hotter background, reduces the observable molecular-line flux far more significantly than the far-IR continuum bands. Simple line-of-sight modeling argues for highly significant departures from the Gao–Solomon relation at high redshift for kinetic temperatures ∼15 K, while more complex toy-galaxy models based on NGC 1068 suggest a much weaker effect with the galaxy integrated HCN line flux falling by only 10% at z = 3, within the intrinsic scatter of the relation. We conclude that, while the CMB is unlikely to explain the deviations reported in the literature, it may introduce a second-order effect on the relation by raising the low-luminosity end of the Gao–Solomon relation in cooler galaxies. A similar examination of the CO-IR relation finds tantalizing signs of the CMB having a measurable effect on the integrated CO emission in high-redshift galaxies, but these signs cannot be confirmed with the current data.

The Role of the CMB in Redshift Related Departures from the Gao–Solomon Relation

International Nuclear Information System (INIS)

Tunnard, R.; Greve, T. R.

2017-01-01

A strong correlation between the far-IR and HCN(1−0) line luminosities, known as the Gao–Solomon relation, has been observed to hold over more than 10 orders of magnitude in the local universe. Departures from this relation at redshifts ≳1.5 have been interpreted as evidence for increased dense gas star formation efficiency in luminous galaxies during the period of peak of star formation in the history of the universe. We examine whether the offsets from the relation can be explained by the hotter Cosmic Microwave Background (CMB) at high redshift, which, due to a loss of contrast against the hotter background, reduces the observable molecular-line flux far more significantly than the far-IR continuum bands. Simple line-of-sight modeling argues for highly significant departures from the Gao–Solomon relation at high redshift for kinetic temperatures ∼15 K, while more complex toy-galaxy models based on NGC 1068 suggest a much weaker effect with the galaxy integrated HCN line flux falling by only 10% at z = 3, within the intrinsic scatter of the relation. We conclude that, while the CMB is unlikely to explain the deviations reported in the literature, it may introduce a second-order effect on the relation by raising the low-luminosity end of the Gao–Solomon relation in cooler galaxies. A similar examination of the CO-IR relation finds tantalizing signs of the CMB having a measurable effect on the integrated CO emission in high-redshift galaxies, but these signs cannot be confirmed with the current data.

TESTING CPT SYMMETRY WITH CURRENT AND FUTURE CMB MEASUREMENTS

Energy Technology Data Exchange (ETDEWEB)

Li, Si-Yu; Zhang, Xinmin [Theory Division, Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-4, Beijing 100049 (China); Xia, Jun-Qing; Li, Hong [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-3, Beijing 100049 (China); Li, Mingzhe, E-mail: xiajq@ihep.ac.cn [Interdisciplinary Center for Theoretical Study, University of Science and Technology of China, Hefei, Anhui 230026 (China)

2015-02-01

In this paper, we use the current and future cosmic microwave background (CMB) experiments to test the Charge-Parity-Time Reversal (CPT) symmetry. We consider a CPT-violating interaction in the photon sector L{sub cs}∼p{sub μ}A{sub ν} F-tilde {sup μν}, which gives rise to a rotation of the polarization vectors of the propagating CMB photons. By combining the 9 yr WMAP, BOOMERanG 2003, and BICEP1 observations, we obtain the current constraint on the isotropic rotation angle α-bar =−2.12±1.14 (1σ), indicating that the significance of the CPT violation is about 2σ. Here, we particularly take the systematic errors of CMB measurements into account. Then, we study the effects of the anisotropies of the rotation angle [Δα( n-hat )] on the CMB polarization power spectra in detail. Due to the small effects, the current CMB polarization data cannot constrain the related parameters very well. We obtain the 95% C.L. upper limit of the variance of the anisotropies of the rotation angle C {sup α}(0) < 0.035 from all of the CMB data sets. More interestingly, including the anisotropies of rotation angle could lower the best-fit value of r and relax the tension on the constraints of r between BICEP2 and Planck. Finally, we investigate the capabilities of future Planck polarization measurements on α-bar and Δα( n-hat ). Benefited from the high precision of Planck data, the constraints of the rotation angle can be significantly improved.

Isotropic blackbody cosmic microwave background radiation as evidence for a homogeneous universe.

Science.gov (United States)

Clifton, Timothy; Clarkson, Chris; Bull, Philip

2012-08-03

The question of whether the Universe is spatially homogeneous and isotropic on the largest scales is of fundamental importance to cosmology but has not yet been answered decisively. Surprisingly, neither an isotropic primary cosmic microwave background (CMB) nor combined observations of luminosity distances and galaxy number counts are sufficient to establish such a result. The inclusion of the Sunyaev-Zel'dovich effect in CMB observations, however, dramatically improves this situation. We show that even a solitary observer who sees an isotropic blackbody CMB can conclude that the Universe is homogeneous and isotropic in their causal past when the Sunyaev-Zel'dovich effect is present. Critically, however, the CMB must either be viewed for an extended period of time, or CMB photons that have scattered more than once must be detected. This result provides a theoretical underpinning for testing the cosmological principle with observations of the CMB alone.

Asymmetric beams and CMB statistical anisotropy

International Nuclear Information System (INIS)

Hanson, Duncan; Lewis, Antony; Challinor, Anthony

2010-01-01

Beam asymmetries result in statistically anisotropic cosmic microwave background (CMB) maps. Typically, they are studied for their effects on the CMB power spectrum, however they more closely mimic anisotropic effects such as gravitational lensing and primordial power asymmetry. We discuss tools for studying the effects of beam asymmetry on general quadratic estimators of anisotropy, analytically for full-sky observations as well as in the analysis of realistic data. We demonstrate this methodology in application to a recently detected 9σ quadrupolar modulation effect in the WMAP data, showing that beams provide a complete and sufficient explanation for the anomaly.

What will we learn from the CMB?

International Nuclear Information System (INIS)

Dodelson, S.

1997-10-01

Within the next decade, experiments measuring the anisotropies in the cosmic microwave background (CMB) will add greatly to our knowledge of the universe. There are dozens of experiments scheduled to take data over the next several years, capped by the satellite missions of NASA (MAP) and ESA (PLANCK). What will we learn from these experiments? I argue that the potential pay-off is immense: We are quite likely to determine cosmological parameters to unprecedented accuracy. This will provide key information about the theory of structure formation and even about the physics behind inflation. If the experiments succeed, can anything spoil this pay-off? I focus on three possible spoilers - foregrounds, reionization, and defect models - and argue that we have every reason to be optimistic

To the problem of the secondary CMB anisotropy separation

Directory of Open Access Journals (Sweden)

Verkhodanov Oleg

2016-01-01

Full Text Available We study contribution to the secondary anisotropy maps of cosmic microwave background (CMB radiation which difficult to account for faint sources. Two effects are investigated. They are the Sunyaev–Zeldovich effect connected with the inverse Compton scattering of CMB photons on hot electrons of cluster of galaxies, and contamination of the background by weak extragalctic sources. First, we study fields of the Planck CMB maps around radio sources of the RATAN-600 catalog. We see weak microwave sources which make an additional contribution to the secondary anisotropy on angular small scales (< 7′. An algorithm for selecting candidate objects with the Sunyaev–Zeldovich effect was proposed, based on the use of data on the radio spectral indices and the signal in cosmic-microwave background maps. Second, applying the stacking method, we examine the areas of the CMB maps, constructed according to the Planck Space Observatory data in the neighborhood of different populations of radio sources and giant elliptical galaxies. The samples of objects include giant radio galaxies (GRG, radio sources, selected by the radio spectral index and redshift, as well as the gammaray bursts, used as a secondary comparative sample. The signal from this objects exists on CMB maps and its difference in the neighborhood of GRGs from the other types of objects was discovered.

CMB probes on the correlated axion isocurvature perturbation

International Nuclear Information System (INIS)

Kadota, Kenji; Gong, Jinn-Ouk; Ichiki, Kiyotomo; Matsubara, Takahiko

2015-01-01

We explore the possible cosmological consequence of the gravitational coupling between the inflaton and axion-like fields. In view of the forthcoming cosmic microwave background (CMB) polarization and lensing data, we study the sensitivity of the CMB data on the cross-correlation between the curvature and axion isocurvature perturbations. Through a concrete example, we illustrate the explicit dependence of the scale dependent cross-correlation power spectrum on the axion parameters

Big bang nucleosynthesis, the CMB, and the origin of matter and space-time

Science.gov (United States)

Mathews, Grant J.; Gangopadhyay, Mayukh; Sasankan, Nishanth; Ichiki, Kiyotomo; Kajino, Toshitaka

2018-04-01

We summarize some applications of big bang nucleosythesis (BBN) and the cosmic microwave background (CMB) to constrain the first moments of the creation of matter in the universe. We review the basic elements of BBN and how it constraints physics of the radiation-dominated epoch. In particular, how the existence of higher dimensions impacts the cosmic expansion through the projection of curvature from the higher dimension in the "dark radiation" term. We summarize current constraints from BBN and the CMB on this brane-world dark radiation term. At the same time, the existence of extra dimensions during the earlier inflation impacts the tensor to scalar ratio and the running spectral index as measured in the CMB. We summarize how the constraints on inflation shift when embedded in higher dimensions. Finally, one expects that the universe was born out of a complicated multiverse landscape near the Planck time. In these moments the energy scale of superstrings was obtainable during the early moments of chaotic inflation. We summarize the quest for cosmological evidence of the birth of space-time out of the string theory landscape. We will explore the possibility that a superstring excitations may have made itself known via a coupling to the field of inflation. This may have left an imprint of "dips" in the power spectrum of temperature fluctuations in the cosmic microwave background. The identification of this particle as a superstring is possible because there may be evidence for different oscillator states of the same superstring that appear on different scales on the sky. It will be shown that from this imprint one can deduce the mass, number of oscillations, and coupling constant for the superstring. Although the evidence is marginal, this may constitute the first observation of a superstring in Nature.

A New Limit on CMB Circular Polarization from SPIDER

Science.gov (United States)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; Benton, S. J.; Bergman, A. S.; Bihary, R.; Bock, J. J.; Bond, J. R.; Bryan, S. A.; Chiang, H. C.; Contaldi, C. R.; Doré, O.; Duivenvoorden, A. J.; Eriksen, H. K.; Farhang, M.; Filippini, J. P.; Fissel, L. M.; Fraisse, A. A.; Freese, K.; Galloway, M.; Gambrel, A. E.; Gandilo, N. N.; Ganga, K.; Gudmundsson, J. E.; Halpern, M.; Hartley, J.; Hasselfield, M.; Hilton, G.; Holmes, W.; Hristov, V. V.; Huang, Z.; Irwin, K. D.; Jones, W. C.; Kuo, C. L.; Kermish, Z. D.; Li, S.; Mason, P. V.; Megerian, K.; Moncelsi, L.; Morford, T. A.; Netterfield, C. B.; Nolta, M.; Padilla, I. L.; Racine, B.; Rahlin, A. S.; Reintsema, C.; Ruhl, J. E.; Runyan, M. C.; Ruud, T. M.; Shariff, J. A.; Soler, J. D.; Song, X.; Trangsrud, A.; Tucker, C.; Tucker, R. S.; Turner, A. D.; Van Der List, J. F.; Weber, A. C.; Wehus, I. K.; Wiebe, D. V.; Young, E. Y.

2017-08-01

We present a new upper limit on cosmic microwave background (CMB) circular polarization from the 2015 flight of Spider, a balloon-borne telescope designed to search for B-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the nonzero circular-to-linear polarization coupling of the half-wave plate polarization modulators, data from Spider's 2015 Antarctic flight provide a constraint on Stokes V at 95 and 150 GHz in the range 33< {\\ell }< 307. No other limits exist over this full range of angular scales, and Spider improves on the previous limit by several orders of magnitude, providing 95% C.L. constraints on {\\ell }({\\ell }+1){C}{\\ell }{VV}/(2π ) ranging from 141 to 255 μK2 at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain even stronger constraints on circular polarization.

FSD: Frequency Space Differential measurement of CMB spectral distortions

Science.gov (United States)

Mukherjee, Suvodip; Silk, Joseph; Wandelt, Benjamin D.

2018-04-01

Although the Cosmic Microwave Background agrees with a perfect blackbody spectrum within the current experimental limits, it is expected to exhibit certain spectral distortions with known spectral properties. We propose a new method, Frequency Space Differential (FSD) to measure the spectral distortions in the CMB spectrum by using the inter-frequency differences of the brightness temperature. The difference between the observed CMB temperature at different frequencies must agree with the frequency derivative of the blackbody spectrum, in the absence of any distortion. However, in the presence of spectral distortions, the measured inter-frequency differences would also exhibit deviations from blackbody which can be modeled for known sources of spectral distortions like y & μ. Our technique uses FSD information for the CMB blackbody, y, μ or any other sources of spectral distortions to model the observed signal. Successful application of this method in future CMB missions can provide an alternative method to extract spectral distortion signals and can potentially make it feasible to measure spectral distortions without an internal blackbody calibrator.

A New Limit on CMB Circular Polarization from SPIDER

Energy Technology Data Exchange (ETDEWEB)

Nagy, J. M.; Ade, P. A. R.; Amiri, M.; Benton, S. J.; Bergman, A. S.; Bihary, R.; Bock, J. J.; Bond, J. R.; Bryan, S. A.; Chiang, H. C.; Contaldi, C. R.; Doré, O.; Duivenvoorden, A. J.; Eriksen, H. K.; Farhang, M.; Filippini, J. P.; Fissel, L. M.; Fraisse, A. A.; Freese, K.; Galloway, M.; Gambrel, A. E.; Gandilo, N. N.; Ganga, K.; Gudmundsson, J. E.; Halpern, M.; Hartley, J.; Hasselfield, M.; Hilton, G.; Holmes, W.; Hristov, V. V.; Huang, Z.; Irwin, K. D.; Jones, W. C.; Kuo, C. L.; Kermish, Z. D.; Li, S.; Mason, P. V.; Megerian, K.; Moncelsi, L.; Morford, T. A.; Netterfield, C. B.; Nolta, M.; Padilla, I. L.; Racine, B.; Rahlin, A. S.; Reintsema, C.; Ruhl, J. E.; Runyan, M. C.; Ruud, T. M.; Shariff, J. A.; Soler, J. D.; Song, X.; Trangsrud, A.; Tucker, C.; Tucker, R. S.; Turner, A. D.; List, J. F. Van Der; Weber, A. C.; Wehus, I. K.; Wiebe, D. V.; Young, E. Y.

2017-08-01

We present a new upper limit on CMB circular polarization from the 2015 flight of SPIDER, a balloon-borne telescope designed to search for $B$-mode linear polarization from cosmic inflation. Although the level of circular polarization in the CMB is predicted to be very small, experimental limits provide a valuable test of the underlying models. By exploiting the non-zero circular-to-linear polarization coupling of the HWP polarization modulators, data from SPIDER's 2015 Antarctic flight provides a constraint on Stokes $V$ at 95 and 150 GHz from $33<\\ell<307$. No other limits exist over this full range of angular scales, and SPIDER improves upon the previous limit by several orders of magnitude, providing 95% C.L. constraints on $\\ell (\\ell+1)C_{\\ell}^{VV}/(2\\pi)$ ranging from 141 $\\mu K ^2$ to 203 $\\mu K ^2$ at 150 GHz for a thermal CMB spectrum. As linear CMB polarization experiments become increasingly sensitive, the techniques described in this paper can be applied to obtain stronger constraints on circular polarization.

Taking the Measure of the Universe

Science.gov (United States)

Hinshaw, Gary

2009-01-01

The cosmic microwave background (CMB) radiation is the oldest light in the universe - it is literally the remnant heat left over from the Big Bang. This fossil relic has survived largely intact and it provides us with a unique probe of conditions in the early universe, long before any stars or galaxies had formed. NASA has now flown two satellites devoted to studying the CMB: 'COBE' and 'WMAP'. In this lecture I will describe what we have learned from these missions including: evidence for the Big Bang itself; new measurements of the age, shape, and content of the universe; and new evidence that all structure in the universe emerged from microscopic quantum fluctuations in the primordial soup.

Cosmology with clusters in the CMB

International Nuclear Information System (INIS)

Majumdar, Subhabrata

2008-01-01

Ever since the seminal work by Sunyaev and Zel'dovich describing the distortion of the CMB spectrum, due to photons passing through the hot inter cluster gas on its way to us from the surface of last scattering (the so called Sunyaev-Zel'dovich effect (SZE)), small scale distortions of the CMB by clusters has been used to detect clusters as well as to do cosmology with clusters. Cosmology with clusters in the CMB can be divided into three distinct regimes: a) when the clusters are completely unresolved and contribute to the secondary CMB distortions power spectrum at small angular scales; b) when we can just about resolve the clusters so as to detect the clusters through its total SZE flux such that the clusters can be tagged and counted for doing cosmology and c) when we can completely resolve the clusters so as to measure their sizes and other cluster structural properties and their evolution with redshift. In this article, we take a look at these three aspects of SZE cluster studies and their implication for using clusters as cosmological probes. We show that clusters can be used as effective probes of cosmology, when in all of these three cases, one explores the synergy between cluster physics and cosmology as well take clues about cluster physics from the latest high precision cluster observations (for example, from Chandra and XMM - Newton). As a specific case, we show how an observationally motivated cluster SZ template can explain the CBI-excess without the need for a high σ 8 . We also briefly discuss 'self-calibration' in cluster surveys and the prospect of using clusters as an ensemble of cosmic rulers to break degeneracies arising in cluster cosmology.

Needlet estimation of cross-correlation between CMB lensing maps and LSS

Energy Technology Data Exchange (ETDEWEB)

Bianchini, Federico [Astrophysics Sector, SISSA, Via Bonomea 265, I-34136 Trieste (Italy); Renzi, Alessandro; Marinucci, Domenico, E-mail: fbianchini@sissa.it, E-mail: renzi@mat.uniroma2.it, E-mail: marinucc@mat.uniroma2.it [Dipartimento di Matematica, Università di Roma Tor Vergata, Via della Ricerca Scientifica 1, 00133 Roma (Italy)

2016-11-01

In this paper we develop a novel needlet-based estimator to investigate the cross-correlation between cosmic microwave background (CMB) lensing maps and large-scale structure (LSS) data. We compare this estimator with its harmonic counterpart and, in particular, we analyze the bias effects of different forms of masking. In order to address this bias, we also implement a MASTER-like technique in the needlet case. The resulting estimator turns out to have an extremely good signal-to-noise performance. Our analysis aims at expanding and optimizing the operating domains in CMB-LSS cross-correlation studies, similarly to CMB needlet data analysis. It is motivated especially by next generation experiments (such as Euclid) which will allow us to derive much tighter constraints on cosmological and astrophysical parameters through cross-correlation measurements between CMB and LSS.

Signatures of graviton masses on the CMB

Science.gov (United States)

Brax, Philippe; Cespedes, Sebastian; Davis, Anne-Christine

2018-03-01

The impact of the existence of gravitons with non-vanishing masses on the B-modes of the Cosmic Microwave Background (CMB) is investigated. We also focus on putative modifications to the speed of the gravitational waves. We find that a change of the graviton speed shifts the acoustic peaks of the CMB and then could be easily constrained. For the case of massive gravity, we show analytically how the B-modes are sourced in a manner differing from the massless case leading to a plateau at low l in the CMB spectrum. We also study the case when there are more than one graviton, and when pressure instabilities are present. The latter would occur in doubly coupled bigravity in the radiation era. We focus on the case where a massless graviton becomes tachyonic in the radiation era whilst a massive one remains stable. As the unstable mode decouples from matter in the radiation era, we find that the effects of the instability is largely reduced on the spectrum of B-modes as long as the unstable graviton does not grow into the non-linear regime. In all cases when both massless and massive gravitons are present, we find that the B-mode CMB spectrum is characterised by a low l plateau together with a shifted position for the first few peaks compared to a purely massive graviton spectrum, a shift which depends on the mixing between the gravitons in their coupling to matter and could serve as a hint in favour of the existence of multiple gravitons.

Anisotropic cosmological constant and the CMB quadrupole anomaly

International Nuclear Information System (INIS)

Rodrigues, Davi C.

2008-01-01

There are evidences that the cosmic microwave background (CMB) large-angle anomalies imply a departure from statistical isotropy and hence from the standard cosmological model. We propose a ΛCDM model extension whose dark energy component preserves its nondynamical character but wields anisotropic vacuum pressure. Exact solutions for the cosmological scale factors are presented, upper bounds for the deformation parameter are evaluated and its value is estimated considering the elliptical universe proposal to solve the quadrupole anomaly. This model can be constructed from a Bianchi I cosmology with a cosmological constant from two different ways: (i) a straightforward anisotropic modification of the vacuum pressure consistently with energy-momentum conservation; (ii) a Poisson structure deformation between canonical momenta such that the dynamics remain invariant under scale factors rescalings

Cosmology from CMB Polarization with POLARBEAR and the Simons Array

Science.gov (United States)

Barron, Darcy; POLARBEAR Collaboration

2018-01-01

POLARBEAR is a cosmic microwave background (CMB) polarization experiment located in the Atacama desert in Chile. The science goals of the POLARBEAR project are to do a deep search for CMB B-mode polarization created by inflationary gravitational waves, as well as characterize the CMB B-mode signal from gravitational lensing. POLARBEAR-1 started observations in 2012, and the POLARBEAR team has published a series of results from its first season of observations, including the first measurement of a non-zero B-mode polarization angular power spectrum, measured at sub-degree scales where the dominant signal is gravitational lensing of the CMB. Recently, we released an improved measurement of the B-mode polarization power spectrum, improving our band-power uncertainties by a factor of two, by adding new data from our second observing season and re-analyzing the combined data set.To further improve on these measurements, POLARBEAR is expanding to include an additional two telescopes with multi-chroic receivers observing at 95, 150, 220, and 270 GHz, known as the Simons Array. With high sensitivity and large sky coverage, the Simons Array will create a detailed survey of B-mode polarization, and its spectral information will be used to extract the CMB signal from astrophysical foregrounds. We will present the latest POLARBEAR results, as well as the status of development of the Simons Array and its expected capabilities.

Planck-scale sensitivity of CMB polarization data

Energy Technology Data Exchange (ETDEWEB)

Gubitosi, Giulia; Pagano, Luca [Physics Department, University of Rome ' La Sapienza' , and Sezione Roma1 INFN P.le Aldo Moro 2, 00185 Rome (Italy)

2009-10-15

We show that the Cosmic Microwave Background (CMB) polarization data gathered by the BOOMERanG 2003 flight and WMAP provide an opportunity to investigate in-vacuo birefringence, of a type expected in some quantum pictures of space-time, with a sensitivity that extends even beyond the desired Planck-scale energy. In order to render this constraint more transparent we rely on a well studied phenomenological model of quantum-gravity-induced birefringence, in which one easily establishes that effects introduced at the Planck scale would amount to values of a dimensionless parameter, denoted by xi, with respect to the Planck energy which are roughly of order 1. By combining BOOMERanG and WMAP data we estimate xiapprox =-0.097+-0.075 at the 68% c.l. Moreover, we forecast on the sensitivity to xi achievable by future CMB polarization experiments (PLANCK, Spider, EPIC), which, in the absence of systematics, will be at the 1-sigma confidence of 8.5x10{sup -4} (PLANCK), 6.1x10{sup -3} (Spider), and 1.0x10{sup -5} (EPIC) respectively. The cosmic variance-limited sensitivity from CMB is 6.1x10{sup -6}.

Planck-scale sensitivity of CMB polarization data

International Nuclear Information System (INIS)

Gubitosi, Giulia; Pagano, Luca

2009-01-01

We show that the Cosmic Microwave Background (CMB) polarization data gathered by the BOOMERanG 2003 flight and WMAP provide an opportunity to investigate in-vacuo birefringence, of a type expected in some quantum pictures of space-time, with a sensitivity that extends even beyond the desired Planck-scale energy. In order to render this constraint more transparent we rely on a well studied phenomenological model of quantum-gravity-induced birefringence, in which one easily establishes that effects introduced at the Planck scale would amount to values of a dimensionless parameter, denoted by ξ, with respect to the Planck energy which are roughly of order 1. By combining BOOMERanG and WMAP data we estimate ξ≅-0.097±0.075 at the 68% c.l. Moreover, we forecast on the sensitivity to ξ achievable by future CMB polarization experiments (PLANCK, Spider, EPIC), which, in the absence of systematics, will be at the 1-σ confidence of 8.5x10 -4 (PLANCK), 6.1x10 -3 (Spider), and 1.0x10 -5 (EPIC) respectively. The cosmic variance-limited sensitivity from CMB is 6.1x10 -6 .

CMB-S4 Science Book, First Edition

Energy Technology Data Exchange (ETDEWEB)

Abazajian, Kevork N. [Univ. of California, Irvine, CA (United States); et al.

2016-10-09

This book lays out the scientific goals to be addressed by the next-generation ground-based cosmic microwave background experiment, CMB-S4, envisioned to consist of dedicated telescopes at the South Pole, the high Chilean Atacama plateau and possibly a northern hemisphere site, all equipped with new superconducting cameras. CMB-S4 will dramatically advance cosmological studies by crossing critical thresholds in the search for the B-mode polarization signature of primordial gravitational waves, in the determination of the number and masses of the neutrinos, in the search for evidence of new light relics, in constraining the nature of dark energy, and in testing general relativity on large scales.

The Kolmogorov-Smirnov test for the CMB

International Nuclear Information System (INIS)

Frommert, Mona; Durrer, Ruth; Michaud, Jérôme

2012-01-01

We investigate the statistics of the cosmic microwave background using the Kolmogorov-Smirnov test. We show that, when we correctly de-correlate the data, the partition function of the Kolmogorov stochasticity parameter is compatible with the Kolmogorov distribution and, contrary to previous claims, the CMB data are compatible with Gaussian fluctuations with the correlation function given by standard ΛCDM. We then use the Kolmogorov-Smirnov test to derive upper bounds on residual point source power in the CMB, and indicate the promise of this statistics for further datasets, especially Planck, to search for deviations from Gaussianity and for detecting point sources and Galactic foregrounds

Loop quantum gravity effects on inflation and the CMB

International Nuclear Information System (INIS)

Tsujikawa, Shinji; Singh, Parampreet; Maartens, Roy

2004-01-01

In loop quantum cosmology, the universe avoids a big bang singularity and undergoes an early and short super-inflation phase. During super-inflation, non-perturbative quantum corrections to the dynamics drive an inflaton field up its potential hill, thus setting the initial conditions for standard inflation. We show that this effect can raise the inflaton high enough to achieve sufficient e-foldings in the standard inflation era. We analyse the cosmological perturbations generated when slow-roll is violated after super-inflation and show that loop quantum effects can in principle leave an indirect signature on the largest scales in the CMB, with some loss of power and running of the spectral index

Testing alternative theories of dark matter with the CMB

International Nuclear Information System (INIS)

Li Baojiu; Barrow, John D.; Mota, David F.; Zhao, HongSheng

2008-01-01

We propose a method to study and constrain modified gravity theories for dark matter using CMB temperature anisotropies and polarization. We assume that the theories considered here have already passed the matter power-spectrum test of large-scale structure. With this requirement met, we show that a modified gravity theory can be specified by parametrizing the time evolution of its dark-matter density contrast, which is completely controlled by the dark-matter stress history. We calculate how the stress history with a given parametrization affects the CMB observables, and a qualitative discussion of the physical effects involved is supplemented with numerical examples. It is found that, in general, alternative gravity theories can be efficiently constrained by the CMB temperature and polarization spectra. There exist, however, special cases where modified gravity cannot be distinguished from the CDM model even by using both CMB and matter power spectrum observations, nor can they be efficiently restricted by other observables in perturbed cosmologies. Our results show how the stress properties of dark matter, which determine the evolutions of both density perturbations and the gravitational potential, can be effectively investigated using just the general conservation equations and without assuming any specific theoretical gravitational theory within a wide class.

A Measurement of CMB Cluster Lensing with SPT and DES Year 1 Data

Energy Technology Data Exchange (ETDEWEB)

Baxter, E.J.; et al.

2017-08-03

Clusters of galaxies gravitationally lens the cosmic microwave background (CMB) radiation, resulting in a distinct imprint in the CMB on arcminute scales. Measurement of this effect offers a promising way to constrain the masses of galaxy clusters, particularly those at high redshift. We use CMB maps from the South Pole Telescope Sunyaev-Zel'dovich (SZ) survey to measure the CMB lensing signal around galaxy clusters identified in optical imaging from first year observations of the Dark Energy Survey. We detect lensing of the CMB by the galaxy clusters at 6.5$\\sigma$ significance. Using the measured lensing signal, we constrain the amplitude of the relation between cluster mass and optical richness to roughly $20\\%$ precision, finding good agreement with recent constraints obtained with galaxy lensing. The error budget is dominated by statistical noise but includes significant contributions from systematic biases due to the thermal SZ effect and cluster miscentering.

CMBPol Mission Concept Study: Probing Inflation with CMB Polarization

CERN Document Server

Baumann, Daniel; Adshead, Peter; Amblard, Alexandre; Ashoorioon, Amjad; Bartolo, Nicola; Bean, Rachel; Beltran, Maria; de Bernardis, Francesco; Bird, Simeon; Chen, Xingang; Chung, Daniel Jun Hun; Colombo, Loris; Cooray, Asantha R.; Creminelli, Paolo; Dodelson, Scott; Dunkley, Joanna; Dvorkin, Cora; Easther, Richard; Finelli, Fabio; Flauger, Raphael; Hertzberg, Mark P.; Jones-Smith, Katherine; Kachru, Shamit; Kadota, Kenji; Khoury, Justin; Kinney, William H.; Komatsu, Eiichiro; Krauss, Lawrence M.; Lesgourgues, Julien; Liddle, Andrew R.; Liguori, Michele; Lim, Eugene A.; Linde, Andrei D.; Matarrese, Sabino; Mathur, Harsh; McAllister, Liam; Melchiorri, Alessandro; Nicolis, Alberto; Pagano, Luca; Peiris, Hiranya V.; Peloso, Marco; Pogosian, Levon; Pierpaoli, Elena; Riotto, Antonio; Seljak, Uros; Senatore, Leonardo; Shandera, Sarah E.; Silverstein, Eva; Smith, Tristan; Vaudrevange, Pascal M.; Verde, Licia; Wandelt, Ben; Wands, David; Watson, Scott; Wyman, Mark; Yadav, Amit; Valkenburg, Wessel; Zaldarriaga, Matias

2009-01-01

We summarize the utility of precise cosmic microwave background (CMB) polarization measurements as probes of the physics of inflation. We focus on the prospects for using CMB measurements to differentiate various inflationary mechanisms. In particular, a detection of primordial B-mode polarization would demonstrate that inflation occurred at a very high energy scale, and that the inflaton traversed a super-Planckian distance in field space. We explain how such a detection or constraint would illuminate aspects of physics at the Planck scale. Moreover, CMB measurements can constrain the scale-dependence and non-Gaussianity of the primordial fluctuations and limit the possibility of a significant isocurvature contribution. Each such limit provides crucial information on the underlying inflationary dynamics. Finally, we quantify these considerations by presenting forecasts for the sensitivities of a future satellite experiment to the inflationary parameters.

Constraints on reconstructed dark energy model from SN Ia and BAO/CMB observations

Energy Technology Data Exchange (ETDEWEB)

Mamon, Abdulla Al [Manipal University, Manipal Centre for Natural Sciences, Manipal (India); Visva-Bharati, Department of Physics, Santiniketan (India); Bamba, Kazuharu [Fukushima University, Division of Human Support System, Faculty of Symbiotic Systems Science, Fukushima (Japan); Das, Sudipta [Visva-Bharati, Department of Physics, Santiniketan (India)

2017-01-15

The motivation of the present work is to reconstruct a dark energy model through the dimensionless dark energy function X(z), which is the dark energy density in units of its present value. In this paper, we have shown that a scalar field φ having a phenomenologically chosen X(z) can give rise to a transition from a decelerated to an accelerated phase of expansion for the universe. We have examined the possibility of constraining various cosmological parameters (such as the deceleration parameter and the effective equation of state parameter) by comparing our theoretical model with the latest Type Ia Supernova (SN Ia), Baryon Acoustic Oscillations (BAO) and Cosmic Microwave Background (CMB) radiation observations. Using the joint analysis of the SN Ia+BAO/CMB dataset, we have also reconstructed the scalar potential from the parametrized X(z). The relevant potential is found, a polynomial in φ. From our analysis, it has been found that the present model favors the standard ΛCDM model within 1σ confidence level. (orig.)

Small-scale cosmic microwave background anisotropies as probe of the geometry of the universe

Science.gov (United States)

Kamionkowski, Marc; Spergel, David N.; Sugiyama, Naoshi

1994-01-01

We perform detailed calculations of cosmic microwave background (CMB) anisotropies in a cold dark matter (CDM)-dominated open universe with primordial adiabatic density perturbations for a variety of reionization histories. The CMB anisotropies depend primarily on the geometry of the universe, which in a matter-dominated universe is determined by Omega and the optical depth to the surface of last scattering. In particular, the location on the primary Doppler peak depends primarily on Omega and is fairly insensitive to the other unknown parameters, such as Omega(sub b), h, Lambda, and the shape of the power spectrum. Therefore, if the primordial density perturbations are adiabatic, measurements of CMB anisotropies on small scales may be used to determine Omega.

Testing inflation and curvaton scenarios with CMB distortions

International Nuclear Information System (INIS)

Clesse, Sébastien; Garbrecht, Björn; Zhu, Yi

2014-01-01

Prior to recombination, Silk damping causes the dissipation of energy from acoustic waves into the monopole of the Cosmic Microwave Background (CMB), resulting in spectral distortions. These can be used to probe the primordial scalar power spectrum on smaller scales than it is possible with CMB anisotropies. An enhancement of power on these scales is nevertheless required for the resulting distortions to be detectable by future experiments like PIXIE. In this paper, we examine all 49 single-field inflation models listed by Martin et al. in the Encyclopaedia Inflationaris [1] and find that only one of these may lead to a detectable level of distortions in a tuned region of its parameter space, namely the original hybrid model. Three effective multi-field scenarios are also studied: with softly and suddenly turning trajectories, and with a mild waterfall trajectory. Softly turning trajectories do not induce distortions at any detectable level, whereas a sudden turn in the field space or a mild waterfall trajectory predicts a peak (plus damped oscillations in the sudden turn case) in the scalar power spectrum, which can lead to an observable amount of CMB distortions. Finally, another scenario leading to potentially detectable distortions involves a curvaton whose blue spectrum is subdominant on CMB angular scales and overtakes the inflaton spectrum on smaller scales. In this case however, we show that the bounds from ultra compact minihaloes are not satisfied. Expectations for an ultimate PRISM-class experiment characterized by an improvement in sensitivity by a factor of ten are discussed for some models

Testing inflation and curvaton scenarios with CMB distortions

Science.gov (United States)

Clesse, Sébastien; Garbrecht, Björn; Zhu, Yi

2014-10-01

Prior to recombination, Silk damping causes the dissipation of energy from acoustic waves into the monopole of the Cosmic Microwave Background (CMB), resulting in spectral distortions. These can be used to probe the primordial scalar power spectrum on smaller scales than it is possible with CMB anisotropies. An enhancement of power on these scales is nevertheless required for the resulting distortions to be detectable by future experiments like PIXIE. In this paper, we examine all 49 single-field inflation models listed by Martin et al. in the Encyclopaedia Inflationaris [1] and find that only one of these may lead to a detectable level of distortions in a tuned region of its parameter space, namely the original hybrid model. Three effective multi-field scenarios are also studied: with softly and suddenly turning trajectories, and with a mild waterfall trajectory. Softly turning trajectories do not induce distortions at any detectable level, whereas a sudden turn in the field space or a mild waterfall trajectory predicts a peak (plus damped oscillations in the sudden turn case) in the scalar power spectrum, which can lead to an observable amount of CMB distortions. Finally, another scenario leading to potentially detectable distortions involves a curvaton whose blue spectrum is subdominant on CMB angular scales and overtakes the inflaton spectrum on smaller scales. In this case however, we show that the bounds from ultra compact minihaloes are not satisfied. Expectations for an ultimate PRISM-class experiment characterized by an improvement in sensitivity by a factor of ten are discussed for some models.

CMB-S4 and the hemispherical variance anomaly

Science.gov (United States)

O'Dwyer, Márcio; Copi, Craig J.; Knox, Lloyd; Starkman, Glenn D.

2017-09-01

Cosmic microwave background (CMB) full-sky temperature data show a hemispherical asymmetry in power nearly aligned with the Ecliptic. In real space, this anomaly can be quantified by the temperature variance in the Northern and Southern Ecliptic hemispheres, with the Northern hemisphere displaying an anomalously low variance while the Southern hemisphere appears unremarkable [consistent with expectations from the best-fitting theory, Lambda Cold Dark Matter (ΛCDM)]. While this is a well-established result in temperature, the low signal-to-noise ratio in current polarization data prevents a similar comparison. This will change with a proposed ground-based CMB experiment, CMB-S4. With that in mind, we generate realizations of polarization maps constrained by the temperature data and predict the distribution of the hemispherical variance in polarization considering two different sky coverage scenarios possible in CMB-S4: full Ecliptic north coverage and just the portion of the North that can be observed from a ground-based telescope at the high Chilean Atacama plateau. We find that even in the set of realizations constrained by the temperature data, the low Northern hemisphere variance observed in temperature is not expected in polarization. Therefore, observing an anomalously low variance in polarization would make the hypothesis that the temperature anomaly is simply a statistical fluke more unlikely and thus increase the motivation for physical explanations. We show, within ΛCDM, how variance measurements in both sky coverage scenarios are related. We find that the variance makes for a good statistic in cases where the sky coverage is limited, however, full northern coverage is still preferable.

Probing neutrino masses with CMB lensing extraction

International Nuclear Information System (INIS)

Lesgourgues, Julien; Perotto, Laurence; Pastor, Sergio; Piat, Michel

2006-01-01

We evaluate the ability of future cosmic microwave background (CMB) experiments to measure the power spectrum of large scale structure using quadratic estimators of the weak lensing deflection field. We calculate the sensitivity of upcoming CMB experiments such as BICEP, QUaD, BRAIN, ClOVER and Planck to the nonzero total neutrino mass M ν indicated by current neutrino oscillation data. We find that these experiments greatly benefit from lensing extraction techniques, improving their one-sigma sensitivity to M ν by a factor of order four. The combination of data from Planck and the SAMPAN mini-satellite project would lead to σ(M ν )∼0.1 eV, while a value as small as σ(M ν )∼0.035 eV is within the reach of a space mission based on bolometers with a passively cooled 3-4 m aperture telescope, representative of the most ambitious projects currently under investigation. We show that our results are robust not only considering possible difficulties in subtracting astrophysical foregrounds from the primary CMB signal but also when the minimal cosmological model (Λ Mixed Dark Matter) is generalized in order to include a possible scalar tilt running, a constant equation-of-state parameter for the dark energy and/or extra relativistic degrees of freedom

Weak lensing and CMB: Parameter forecasts including a running spectral index

International Nuclear Information System (INIS)

Ishak, Mustapha; Hirata, Christopher M.; McDonald, Patrick; Seljak, Uros

2004-01-01

We use statistical inference theory to explore the constraints from future galaxy weak lensing (cosmic shear) surveys combined with the current CMB constraints on cosmological parameters, focusing particularly on the running of the spectral index of the primordial scalar power spectrum, α s . Recent papers have drawn attention to the possibility of measuring α s by combining the CMB with galaxy clustering and/or the Lyman-α forest. Weak lensing combined with the CMB provides an alternative probe of the primordial power spectrum. We run a series of simulations with variable runnings and compare them to semianalytic nonlinear mappings to test their validity for our calculations. We find that a 'reference' cosmic shear survey with f sky =0.01 and 6.6x10 8 galaxies per steradian can reduce the uncertainty on n s and α s by roughly a factor of 2 relative to the CMB alone. We investigate the effect of shear calibration biases on lensing by including the calibration factor as a parameter, and show that for our reference survey, the precision of cosmological parameter determination is only slightly degraded even if the amplitude calibration is uncertain by as much as 5%. We conclude that in the near future weak lensing surveys can supplement the CMB observations to constrain the primordial power spectrum

The effects of the small-scale behaviour of dark matter power spectrum on CMB spectral distortion

Science.gov (United States)

Sarkar, Abir; Sethi, Shiv. K.; Das, Subinoy

2017-07-01

After numerous astronomical and experimental searches, the precise particle nature of dark matter is still unknown. The standard Weakly Interacting Massive Particle(WIMP) dark matter, despite successfully explaining the large-scale features of the universe, has long-standing small-scale issues. The spectral distortion in the Cosmic Microwave Background(CMB) caused by Silk damping in the pre-recombination era allows one to access information on a range of small scales 0.3 Mpc Light Axion (ULA) dark matter and Charged Decaying Dark Matter (CHDM); the matter power in all these models deviate significantly from the ΛCDM model at small scales. We compute the spectral distortion of CMB for these alternative models and compare our results with the ΛCDM model. We show that the main impact of alternative models is to alter the sub-horizon evolution of the Newtonian potential which affects the late-time behaviour of spectral distortion of CMB. The y-parameter diminishes by a few percent as compared to the ΛCDM model for a range of parameters of these models: LFDM for formation redshift zf = 105 (7%); WDM for mass mwdm = 1 keV (2%); CHDM for decay redshift zdecay = 105 (5%); ULA for mass ma = 10-24 eV (3%). This effect from the pre-recombination era can be masked by orders of magnitude higher y-distortions generated by late-time sources, e.g. the Epoch of Reionization and tSZ from the cluster of galaxies. We also briefly discuss the detectability of this deviation in light of the upcoming CMB experiment PIXIE, which might have the sensitivity to detect this signal from the pre-recombination phase.

Separating the early universe from the late universe: Cosmological parameter estimation beyond the black box

International Nuclear Information System (INIS)

Tegmark, Max; Zaldarriaga, Matias

2002-01-01

We present a method for measuring the cosmic matter budget without assumptions about speculative early Universe physics, and for measuring the primordial power spectrum P * (k) nonparametrically, either by combining CMB and LSS information or by using CMB polarization. Our method complements currently fashionable 'black box' cosmological parameter analysis, constraining cosmological models in a more physically intuitive fashion by mapping measurements of CMB, weak lensing and cluster abundance into k space, where they can be directly compared with each other and with galaxy and Lyα forest clustering. Including the new CBI results, we find that CMB measurements of P(k) overlap with those from 2dF galaxy clustering by over an order of magnitude in scale, and even overlap with weak lensing measurements. We describe how our approach can be used to raise the ambition level beyond cosmological parameter fitting as data improves, testing rather than assuming the underlying physics

The cosmic microwave background how it changed our understanding of the universe

CERN Document Server

Evans, Rhodri

2015-01-01

Rhodri Evans tells the story of what we know about the universe, from Jacobus Kapteyn’s Island universe at the turn of the 20th Century, and the discovery by Hubble that the nebulae were external to our own galaxy, through Gamow’s early work on the cosmic microwave background (CMB) and its subsequent discovery by Penzias and Wilson, to modern day satellite-lead CMB research. Research results from the ground-based experiments DASI, BOOMERANG, and satellite missions COBE, WMAP and Planck are explained and interpreted to show how our current picture of the universe was arrived at, and the author looks at the future of CMB research and what we still need to learn. This account is enlivened by Dr Rhodri Evans' personal connections to the characters and places in the story.

Constraints on Inflation from Polarization and CMB Spectral Distortions

Science.gov (United States)

Kamionkowski, Marc

2014-01-01

This talk will summarize some things we can do with future CMB experiments to study the early Universe. An obvious first is to map the polarization from density perturbations to the cosmic-variance limit to improve upon the types of things (cosmological-parameter determination, lensing, etc.) that have been done so far with the temperature. Another direction, which already has considerable momentum, is the pursuit of the characteristic polarization signature of inflationary gravitational waves. But there is also a strong case, which I will review, now being assembled for a space mission to seek the tiny but nonzero departures from a blackbody spectrum that are expected in the standard cosmological model and that may arise from several interesting exotic mechanisms.

Planck 2013 results. XV. CMB power spectra and likelihood

CERN Document Server

Ade, P.A.R.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartlett, J.G.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chiang, L.Y.; Chiang, H.C.; Christensen, P.R.; Church, S.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.M.; Desert, F.X.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Dunkley, J.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Gaier, T.C.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hansen, F.K.; Hanson, D.; Harrison, D.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Jaffe, T.R.; Jaffe, A.H.; Jewell, J.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T.S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Laureijs, R.J.; Lawrence, C.R.; Le Jeune, M.; Leach, S.; Leahy, J.P.; Leonardi, R.; Leon-Tavares, J.; Lesgourgues, J.; Liguori, M.; Lilje, P.B.; Lindholm, V.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maffei, B.; Maino, D.; Mandolesi, N.; Marinucci, D.; Maris, M.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Menegoni, E.; Mennella, A.; Migliaccio, M.; Millea, M.; Mitra, S.; Miville-Deschenes, M.A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I.J.; Orieux, F.; Osborne, S.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Paykari, P.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Rahlin, A.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ringeval, C.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Sanselme, L.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Starck, J.L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; White, M.; White, S.D.M.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-01-01

We present the Planck likelihood, a complete statistical description of the two-point correlation function of the CMB temperature fluctuations. We use this likelihood to derive the Planck CMB power spectrum over three decades in l, covering 2 = 50, we employ a correlated Gaussian likelihood approximation based on angular cross-spectra derived from the 100, 143 and 217 GHz channels. We validate our likelihood through an extensive suite of consistency tests, and assess the impact of residual foreground and instrumental uncertainties on cosmological parameters. We find good internal agreement among the high-l cross-spectra with residuals of a few uK^2 at l <= 1000. We compare our results with foreground-cleaned CMB maps, and with cross-spectra derived from the 70 GHz Planck map, and find broad agreement in terms of spectrum residuals and cosmological parameters. The best-fit LCDM cosmology is in excellent agreement with preliminary Planck polarisation spectra. The standard LCDM cosmology is well constrained b...

A measurement of CMB cluster lensing with SPT and DES year 1 data

Science.gov (United States)

Baxter, E. J.; Raghunathan, S.; Crawford, T. M.; Fosalba, P.; Hou, Z.; Holder, G. P.; Omori, Y.; Patil, S.; Rozo, E.; Abbott, T. M. C.; Annis, J.; Aylor, K.; Benoit-Lévy, A.; Benson, B. A.; Bertin, E.; Bleem, L.; Buckley-Geer, E.; Burke, D. L.; Carlstrom, J.; Carnero Rosell, A.; Carrasco Kind, M.; Carretero, J.; Chang, C. L.; Cho, H.-M.; Crites, A. T.; Crocce, M.; Cunha, C. E.; da Costa, L. N.; D'Andrea, C. B.; Davis, C.; de Haan, T.; Desai, S.; Dietrich, J. P.; Dobbs, M. A.; Dodelson, S.; Doel, P.; Drlica-Wagner, A.; Estrada, J.; Everett, W. B.; Fausti Neto, A.; Flaugher, B.; Frieman, J.; García-Bellido, J.; George, E. M.; Gaztanaga, E.; Giannantonio, T.; Gruen, D.; Gruendl, R. A.; Gschwend, J.; Gutierrez, G.; Halverson, N. W.; Harrington, N. L.; Hartley, W. G.; Holzapfel, W. L.; Honscheid, K.; Hrubes, J. D.; Jain, B.; James, D. J.; Jarvis, M.; Jeltema, T.; Knox, L.; Krause, E.; Kuehn, K.; Kuhlmann, S.; Kuropatkin, N.; Lahav, O.; Lee, A. T.; Leitch, E. M.; Li, T. S.; Lima, M.; Luong-Van, D.; Manzotti, A.; March, M.; Marrone, D. P.; Marshall, J. L.; Martini, P.; McMahon, J. J.; Melchior, P.; Menanteau, F.; Meyer, S. S.; Miller, C. J.; Miquel, R.; Mocanu, L. M.; Mohr, J. J.; Natoli, T.; Nord, B.; Ogando, R. L. C.; Padin, S.; Plazas, A. A.; Pryke, C.; Rapetti, D.; Reichardt, C. L.; Romer, A. K.; Roodman, A.; Ruhl, J. E.; Rykoff, E.; Sako, M.; Sanchez, E.; Sayre, J. T.; Scarpine, V.; Schaffer, K. K.; Schindler, R.; Schubnell, M.; Sevilla-Noarbe, I.; Shirokoff, E.; Smith, M.; Smith, R. C.; Soares-Santos, M.; Sobreira, F.; Staniszewski, Z.; Stark, A.; Story, K.; Suchyta, E.; Tarle, G.; Thomas, D.; Troxel, M. A.; Vanderlinde, K.; Vieira, J. D.; Walker, A. R.; Williamson, R.; Zhang, Y.; Zuntz, J.

2018-05-01

Clusters of galaxies gravitationally lens the cosmic microwave background (CMB) radiation, resulting in a distinct imprint in the CMB on arcminute scales. Measurement of this effect offers a promising way to constrain the masses of galaxy clusters, particularly those at high redshift. We use CMB maps from the South Pole Telescope Sunyaev-Zel'dovich (SZ) survey to measure the CMB lensing signal around galaxy clusters identified in optical imaging from first year observations of the Dark Energy Survey. The cluster catalogue used in this analysis contains 3697 members with mean redshift of \\bar{z} = 0.45. We detect lensing of the CMB by the galaxy clusters at 8.1σ significance. Using the measured lensing signal, we constrain the amplitude of the relation between cluster mass and optical richness to roughly 17 {per cent} precision, finding good agreement with recent constraints obtained with galaxy lensing. The error budget is dominated by statistical noise but includes significant contributions from systematic biases due to the thermal SZ effect and cluster miscentring.

Thermal analysis of a prototype cryogenic polarization modulator for use in a space-borne CMB polarization experiment

Science.gov (United States)

Iida, T.; Sakurai, Y.; Matsumura, T.; Sugai, H.; Imada, H.; Kataza, H.; Ohsaki, H.; Hazumi, M.; Katayama, N.; Yamamoto, R.; Utsunomiya, S.; Terao, Y.

2017-12-01

We report a thermal analysis of a polarization modulator unit (PMU) for use in a space-borne cosmic microwave background (CMB) project. A measurement of the CMB polarization allows us to probe the physics of early universe, and that is the best method to test the cosmic inflation experimentally. One of the key instruments for this science is to use a halfwave plate (HWP) based polarization modulator. The HWP is required to rotate continuously at about 1 Hz below 10 K to minimize its own thermal emission to a detector system. The rotating HWP system at the cryogenic environment can be realized by using a superconducting magnetic bearing (SMB) without significant heat dissipation by mechanical friction. While the SMB achieves the smooth rotation due to the contactless bearing, an estimation of a levitating HWP temperature becomes a challenge. We manufactured a one-eighth scale prototype model of PMU and built a thermal model. We verified our thermal model with the experimental data. We forecasted the projected thermal performance of PMU for a full-scale model based on the thermal model. From this analysis, we discuss the design requirement toward constructing the full-scale model for use in a space environment such as a future CMB satellite mission, LiteBIRD.

How sensitive is the CMB to a single lens?

Energy Technology Data Exchange (ETDEWEB)

Rathaus, Ben; Fialkov, Anastasia; Itzhaki, Nissan, E-mail: ben.rathaus@gmail.com, E-mail: nitzhaki@post.tau.ac.il, E-mail: anastasia.fialkov@gmail.com [Raymond and Beverly Sackler Faculty of Exact Sciences, School of Physics and Astronomy, Tel-Aviv University, Ramat-Aviv, 69978 (Israel)

2011-06-01

We study the imprints of a single lens, that breaks statistical isotropy, on the CMB and calculate the signal to noise ratio (S/N) for its detection. We emphasize the role of non-Gaussianities induced by ΛCDM weak lensing in this calculation and show that typically the S/N is much smaller than expected. In particular we find that the hypothesis that a void (texture) is responsible for the WMAP cold spot can barely (cannot) be tested via weak lensing of the CMB.

How sensitive is the CMB to a single lens?

International Nuclear Information System (INIS)

Rathaus, Ben; Fialkov, Anastasia; Itzhaki, Nissan

2011-01-01

We study the imprints of a single lens, that breaks statistical isotropy, on the CMB and calculate the signal to noise ratio (S/N) for its detection. We emphasize the role of non-Gaussianities induced by ΛCDM weak lensing in this calculation and show that typically the S/N is much smaller than expected. In particular we find that the hypothesis that a void (texture) is responsible for the WMAP cold spot can barely (cannot) be tested via weak lensing of the CMB

Contribution of domain wall networks to the CMB power spectrum

International Nuclear Information System (INIS)

Lazanu, A.; Martins, C.J.A.P.; Shellard, E.P.S.

2015-01-01

We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined

Contribution of domain wall networks to the CMB power spectrum

Energy Technology Data Exchange (ETDEWEB)

Lazanu, A., E-mail: A.Lazanu@damtp.cam.ac.uk [Centre for Theoretical Cosmology, Department of Applied Mathematics and Theoretical Physics, Wilberforce Road, Cambridge CB3 0WA (United Kingdom); Martins, C.J.A.P., E-mail: Carlos.Martins@astro.up.pt [Centro de Astrofísica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal); Instituto de Astrofísica e Ciências do Espaço, CAUP, Rua das Estrelas, 4150-762 Porto (Portugal); Shellard, E.P.S., E-mail: E.P.S.Shellard@damtp.cam.ac.uk [Centre for Theoretical Cosmology, Department of Applied Mathematics and Theoretical Physics, Wilberforce Road, Cambridge CB3 0WA (United Kingdom)

2015-07-30

We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined.

Contribution of domain wall networks to the CMB power spectrum

Directory of Open Access Journals (Sweden)

A. Lazanu

2015-07-01

Full Text Available We use three domain wall simulations from the radiation era to the late-time dark energy domination era based on the PRS algorithm to calculate the energy–momentum tensor components of domain wall networks in an expanding universe. Unequal time correlators in the radiation, matter and cosmological constant epochs are calculated using the scaling regime of each of the simulations. The CMB power spectrum of a network of domain walls is determined. The first ever quantitative constraint for the domain wall surface tension is obtained using a Markov chain Monte Carlo method; an energy scale of domain walls of 0.93 MeV, which is close but below the Zel'dovich bound, is determined.

CMB polarization at large angular scales: Data analysis of the POLAR experiment

International Nuclear Information System (INIS)

O'Dell, Christopher W.; Keating, Brian G.; Oliveira-Costa, Angelica de; Tegmark, Max; Timbie, Peter T.

2003-01-01

The coming flood of cosmic microwave background (CMB) polarization experiments, spurred by the recent detection of CMB polarization by the DASI and WMAP instruments, will be confronted by many new analysis tasks specific to polarization. For the analysis of CMB polarization data sets, the devil is truly in the details. With this in mind, we present details of the data analysis for the POLAR experiment, which recently led to the tightest upper limits on the polarization of the cosmic microwave background radiation at large angular scales. We discuss the data selection process, map-making algorithms, offset removal, and likelihood analysis which were used to find upper limits on the polarization. Stated using the modern convention for reporting CMB Stokes parameters, these limits are 5.0 μK on both E- and B-type polarization at 95% confidence. Finally, we discuss simulations used to test our analysis techniques and to probe the fundamental limitations of the experiment

Beyond y and μ: the shape of the CMB spectral distortions in the intermediate epoch, 1.5 × 104∼5

International Nuclear Information System (INIS)

Khatri, Rishi; Sunyaev, Rashid A.

2012-01-01

We calculate numerical solutions and analytic approximations for the intermediate-type spectral distortions. Detection of a μ-type distortion (saturated comptonization) in the CMB will constrain the time of energy injection to be at a redshift 2 × 10 6 ∼>z∼>2 × 10 5 , while a detection of a y-type distortion (minimal comptonization) will mean that there was heating of CMB at redshift z∼ 4 . We point out that the partially comptonized spectral distortions, generated in the redshift range 1.5 × 10 4 ∼ 5 , are much richer in information than the pure y and μ-type distortions. The spectrum created during this period is intermediate between y and μ-type distortions and depends sensitively on the redshift of energy injection. These intermediate-type distortions cannot be mimicked by a mixture of y and μ-type distortions at all frequencies and vice versa. The measurement of these intermediate-type CMB spectral distortions has the possibility to constrain precisely not only the amount of energy release in the early Universe but also the mechanism, for example, particle annihilation and Silk damping can be distinguished from particle decay. The intermediate-type distortion templates and software code using these templates to calculate the CMB spectral distortions for user-defined energy injection rate is made publicly available

BICEP2, Planck, spinorial space-time, pre-Big Bang.. On the possible origin of primordial CMB B-modes and gravitational waves. Potentialities of alternative cosmologies and open questions

Science.gov (United States)

Gonzalez-Mestres, Luis

2015-05-01

The field of Cosmology is currently undergoing a positive and constructive crisis. Controversies concerning inflation are not really new. But after the 2013-2014 Planck and BICEP2 announcements, and the more recent joint analysis by Planck, BICEP2 and the Keck Array (PBKA), the basic issues can involve more direct links between the Mathematical Physics aspects of cosmological patterns and the interpretation of experimental results. Open questions and new ideas on the foundations of Cosmology can emerge, while future experimental and observational programs look very promising. The BICEP2 result reporting an excess of B-mode polarization signal of the cosmic microwave background (CMB) radiation was initially presented as a signature of primordial gravitational waves from cosmic inflation. But polarized dust emission can be at the origin of such a signal, and the evidence claimed by BICEP2 is no longer secure after the PBKA analysis. Furthermore, even assuming that significant CMB B-mode polarization has indeed been generated by the early Universe, its theoretical and cosmological interpretation would be far from obvious. Inflationary gravitational waves are not the only possible source of primordial CMB B-modes. Alternative cosmologies such as pre-Big Bang patterns and the spinorial space-time (SST) we introduced in 1996-97 can naturally produce this polarization. Furthermore, the SST automatically generates for each comoving observer a local privileged space direction (PSD) whose existence may have been confirmed by Planck data. If such a PSD exists, vector perturbations have most likely been strong in the early Universe and may have produced CMB B-modes. Pre-Big Bang cosmologies can also generate gravitational waves in the early Universe without inflation. After briefly describing detectors devoted to the study of the CMB polarization, we discuss the situation emerging from BICEP2 results, Planck results and the PBKA analysis. In particular, we further analyze

Pre-Inflationary Relics in the CMB?

CERN Document Server

Gruppuso, A.; Mandolesi, N.; Natoli, P.; Sagnotti, A.

String Theory and Supergravity allow, in principle, to follow the transition of the inflaton from pre-inflationary fast roll to slow roll. This introduces an infrared depression in the primordial power spectrum that might have left an imprint in the CMB anisotropy, if it occurred at accessible wavelengths. We model the effect extending $\\Lambda$CDM with a scale $\\Delta$ related to the infrared depression and explore the constraints allowed by {\\sc Planck} data, employing also more conservative, wider Galactic masks in the low resolution CMB likelihood. In an extended mask with $f_{sky}=39\\%$, we thus find $\\Delta = (0.351 \\pm 0.114) \\times 10^{-3} \\, \\mbox{Mpc}^{-1}$, at $99.4\\%$ confidence level, to be compared with a nearby value at $88.5\\%$ with the standard $f_{sky}=94\\%$ mask. With about 64 $e$--folds of inflation, these values for $\\Delta$ would translate into primordial energy scales ${\\cal O}(10^{14})$ GeV.

Beyond CMB cosmic variance limits on reionization with the polarized Sunyaev-Zel'dovich effect

Science.gov (United States)

Meyers, Joel; Meerburg, P. Daniel; van Engelen, Alexander; Battaglia, Nicholas

2018-05-01

Upcoming cosmic microwave background (CMB) surveys will soon make the first detection of the polarized Sunyaev-Zel'dovich effect, the linear polarization generated by the scattering of CMB photons on the free electrons present in collapsed objects. Measurement of this polarization along with knowledge of the electron density of the objects allows a determination of the quadrupolar temperature anisotropy of the CMB as viewed from the space-time location of the objects. Maps of these remote temperature quadrupoles have several cosmological applications. Here we propose a new application: the reconstruction of the cosmological reionization history. We show that with quadrupole measurements out to redshift 3, constraints on the mean optical depth can be improved by an order of magnitude beyond the CMB cosmic variance limit.

Constraints on early dark energy from CMB lensing and weak lensing tomography

International Nuclear Information System (INIS)

Hollenstein, Lukas; Crittenden, Robert; Sapone, Domenico; Schäfer, Björn Malte

2009-01-01

Dark energy can be studied by its influence on the expansion of the Universe as well as on the growth history of the large-scale structure. In this paper, we follow the growth of the cosmic density field in early dark energy cosmologies by combining observations of the primary CMB temperature and polarisation power spectra at high redshift, of the CMB lensing deflection field at intermediate redshift and of weak cosmic shear at low redshifts for constraining the allowed amount of early dark energy. We present these forecasts using the Fisher matrix formalism and consider the combination of Planck data with the weak lensing survey of Euclid. We find that combining these data sets gives powerful constraints on early dark energy and is able to break degeneracies in the parameter set inherent to the various observational channels. The derived statistical 1σ-bound on the early dark energy density parameter is σ(Ω e d ) = 0.0022 which suggests that early dark energy models can be well examined in our approach. In addition, we derive the dark energy figure of merit for the considered dark energy parameterisation and comment on the applicability of the growth index to early dark energy cosmologies

The effects of the small-scale behaviour of dark matter power spectrum on CMB spectral distortion

Energy Technology Data Exchange (ETDEWEB)

Sarkar, Abir; Sethi, Shiv K. [Raman Research Institute, CV Raman Ave Sadashivnagar, Bengaluru, Karnataka 560080 (India); Das, Subinoy, E-mail: abir@rri.res.in, E-mail: sethi@rri.res.in, E-mail: subinoy@iiap.res.in [Indian Institute of Astrophysics, 100 Feet Rd, Madiwala, 2nd Block, Koramangala, Bengaluru, Karnataka 560034 (India)

2017-07-01

After numerous astronomical and experimental searches, the precise particle nature of dark matter is still unknown. The standard Weakly Interacting Massive Particle(WIMP) dark matter, despite successfully explaining the large-scale features of the universe, has long-standing small-scale issues. The spectral distortion in the Cosmic Microwave Background(CMB) caused by Silk damping in the pre-recombination era allows one to access information on a range of small scales 0.3 Mpc < k < 10{sup 4} Mpc{sup −1}, whose dynamics can be precisely described using linear theory. In this paper, we investigate the possibility of using the Silk damping induced CMB spectral distortion as a probe of the small-scale power. We consider four suggested alternative dark matter candidates—Warm Dark Matter (WDM), Late Forming Dark Matter (LFDM), Ultra Light Axion (ULA) dark matter and Charged Decaying Dark Matter (CHDM); the matter power in all these models deviate significantly from the ΛCDM model at small scales. We compute the spectral distortion of CMB for these alternative models and compare our results with the ΛCDM model. We show that the main impact of alternative models is to alter the sub-horizon evolution of the Newtonian potential which affects the late-time behaviour of spectral distortion of CMB. The y -parameter diminishes by a few percent as compared to the ΛCDM model for a range of parameters of these models: LFDM for formation redshift z {sub f} = 10{sup 5} (7%); WDM for mass m {sub wdm} = 1 keV (2%); CHDM for decay redshift z {sub decay} = 10{sup 5} (5%); ULA for mass m {sub a} = 10{sup −24} eV (3%). This effect from the pre-recombination era can be masked by orders of magnitude higher y -distortions generated by late-time sources, e.g. the Epoch of Reionization and tSZ from the cluster of galaxies. We also briefly discuss the detectability of this deviation in light of the upcoming CMB experiment PIXIE, which might have the sensitivity to detect this signal from

A CMB/Dark Energy Cosmic Duality

DEFF Research Database (Denmark)

Enqvist, Kari; Sloth, Martin Snoager

2004-01-01

We investigate a possible connection between the suppression of the power at low multipoles in the CMB spectrum and the late time acceleration. We show that, assuming a cosmic IR/UV duality between the UV cutoff and a global infrared cutoff given by the size of the future event horizon...

Constraining dark sector perturbations I: cosmic shear and CMB lensing

International Nuclear Information System (INIS)

Battye, Richard A.; Moss, Adam; Pearson, Jonathan A.

2015-01-01

We present current and future constraints on equations of state for dark sector perturbations. The equations of state considered are those corresponding to a generalized scalar field model and time-diffeomorphism invariant L(g) theories that are equivalent to models of a relativistic elastic medium and also Lorentz violating massive gravity. We develop a theoretical understanding of the observable impact of these models. In order to constrain these models we use CMB temperature data from Planck, BAO measurements, CMB lensing data from Planck and the South Pole Telescope, and weak galaxy lensing data from CFHTLenS. We find non-trivial exclusions on the range of parameters, although the data remains compatible with w=−1. We gauge how future experiments will help to constrain the parameters. This is done via a likelihood analysis for CMB experiments such as CoRE and PRISM, and tomographic galaxy weak lensing surveys, focussing in on the potential discriminatory power of Euclid on mildly non-linear scales

Constraining dark sector perturbations I: cosmic shear and CMB lensing

Science.gov (United States)

Battye, Richard A.; Moss, Adam; Pearson, Jonathan A.

2015-04-01

We present current and future constraints on equations of state for dark sector perturbations. The equations of state considered are those corresponding to a generalized scalar field model and time-diffeomorphism invariant Script L(g) theories that are equivalent to models of a relativistic elastic medium and also Lorentz violating massive gravity. We develop a theoretical understanding of the observable impact of these models. In order to constrain these models we use CMB temperature data from Planck, BAO measurements, CMB lensing data from Planck and the South Pole Telescope, and weak galaxy lensing data from CFHTLenS. We find non-trivial exclusions on the range of parameters, although the data remains compatible with w=-1. We gauge how future experiments will help to constrain the parameters. This is done via a likelihood analysis for CMB experiments such as CoRE and PRISM, and tomographic galaxy weak lensing surveys, focussing in on the potential discriminatory power of Euclid on mildly non-linear scales.

Echoes of inflationary first-order phase transitions in the CMB

Energy Technology Data Exchange (ETDEWEB)

Jiang, Hongliang, E-mail: hjiangag@connect.ust.hk [Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Special Administrative Region (Hong Kong); Liu, Tao, E-mail: taoliu@ust.hk [Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Special Administrative Region (Hong Kong); Sun, Sichun, E-mail: sichun@uw.edu [Jockey Club Institute for Advanced Study, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Special Administrative Region (Hong Kong); Wang, Yi, E-mail: phyw@ust.hk [Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong Special Administrative Region (Hong Kong)

2017-02-10

Cosmological phase transitions (CPTs), such as the Grand Unified Theory (GUT) and the electroweak (EW) ones, play a significant role in both particle physics and cosmology. In this letter, we propose to probe the first-order CPTs, by detecting gravitational waves (GWs) which are generated during the phase transitions through the cosmic microwave background (CMB). If happened around the inflation era, the first-order CPTs may yield low-frequency GWs due to bubble dynamics, leaving imprints on the CMB. In contrast to the nearly scale-invariant primordial GWs caused by vacuum fluctuation, these bubble-generated GWs are scale dependent and have non-trivial B-mode spectra. If decoupled from inflaton, the EWPT during inflation may serve as a probe for the one after reheating where the baryon asymmetry could be generated via EW baryogenesis (EWBG). The CMB thus provides a potential way to test the feasibility of the EWBG, complementary to the collider measurements of Higgs potential and the direct detection of GWs generated during EWPT.

A Bayesian framework for cosmic string searches in CMB maps

Energy Technology Data Exchange (ETDEWEB)

Ciuca, Razvan; Hernández, Oscar F., E-mail: razvan.ciuca@mail.mcgill.ca, E-mail: oscarh@physics.mcgill.ca [Department of Physics, McGill University, 3600 rue University, Montréal, QC, H3A 2T8 (Canada)

2017-08-01

There exists various proposals to detect cosmic strings from Cosmic Microwave Background (CMB) or 21 cm temperature maps. Current proposals do not aim to find the location of strings on sky maps, all of these approaches can be thought of as a statistic on a sky map. We propose a Bayesian interpretation of cosmic string detection and within that framework, we derive a connection between estimates of cosmic string locations and cosmic string tension G μ. We use this Bayesian framework to develop a machine learning framework for detecting strings from sky maps and outline how to implement this framework with neural networks. The neural network we trained was able to detect and locate cosmic strings on noiseless CMB temperature map down to a string tension of G μ=5 ×10{sup −9} and when analyzing a CMB temperature map that does not contain strings, the neural network gives a 0.95 probability that G μ≤2.3×10{sup −9}.

What can the CMB tell about the microphysics of cosmic reheating?

International Nuclear Information System (INIS)

Drewes, Marco

2016-01-01

In inflationary cosmology, cosmic reheating after inflation sets the initial conditions for the hot big bang. We investigate how CMB data can be used to study the effective potential and couplings of the inflaton during reheating to constrain the underlying microphysics. If there is a phase of preheating that is driven by a parametric resonance or other instability, then the thermal history and expansion history during the reheating era depend on a large number of microphysical parameters in a complicated way. In this case the connection between CMB observables and microphysical parameters can only established with intense numerical studies. Such studies can help to improve CMB constraints on the effective inflaton potential in specific models, but parameter degeneracies usually make it impossible to extract meaningful best-fit values for individual microphysical parameters. If, on the other hand, reheating is driven by perturbative processes, then it can be possible to constrain the inflaton couplings and the reheating temperature from CMB data. This provides an indirect probe of fundamental microphysical parameters that most likely can never be measured directly in the laboratory, but have an immense impact on the evolution of the cosmos by setting the stage for the hot big bang

The cosmic microwave background in an inhomogeneous universe

Energy Technology Data Exchange (ETDEWEB)

Clarkson, Chris; Regis, Marco, E-mail: chris.clarkson@uct.ac.za, E-mail: regis.mrc@gmail.com [Astrophysics, Cosmology and Gravity Centre and Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701, Cape Town (South Africa)

2011-02-01

The dimming of Type Ia supernovae could be the result of Hubble-scale inhomogeneity in the matter and spatial curvature, rather than signaling the presence of a dark energy component. A key challenge for such models is to fit the detailed spectrum of the cosmic microwave background (CMB). We present a detailed discussion of the small-scale CMB in an inhomogeneous universe, focusing on spherically symmetric 'void' models. We allow for the dynamical effects of radiation while analyzing the problem, in contrast to other work which inadvertently fine tunes its spatial profile. This is a surprisingly important effect and we reach substantially different conclusions. Models which are open at CMB distances fit the CMB power spectrum without fine tuning; these models also fit the supernovae and local Hubble rate data which favour a high expansion rate. Asymptotically flat models may fit the CMB, but require some extra assumptions. We argue that a full treatment of the radiation in these models is necessary if we are to understand the correct constraints from the CMB, as well as other observations which rely on it, such as spectral distortions of the black body spectrum, the kinematic Sunyaev-Zeldovich effect or the Baryon Acoustic Oscillations.

Revisiting the EC/CMB model for extragalactic large scale jets

Science.gov (United States)

Lucchini, M.; Tavecchio, F.; Ghisellini, G.

2017-04-01

One of the most outstanding results of the Chandra X-ray Observatory was the discovery that AGN jets are bright X-ray emitters on very large scales, up to hundreds of kpc. Of these, the powerful and beamed jets of flat-spectrum radio quasars are particularly interesting, as the X-ray emission cannot be explained by an extrapolation of the lower frequency synchrotron spectrum. Instead, the most common model invokes inverse Compton scattering of photons of the cosmic microwave background (EC/CMB) as the mechanism responsible for the high-energy emission. The EC/CMB model has recently come under criticism, particularly because it should predict a significant steady flux in the MeV-GeV band which has not been detected by the Fermi/LAT telescope for two of the best studied jets (PKS 0637-752 and 3C273). In this work, we revisit some aspects of the EC/CMB model and show that electron cooling plays an important part in shaping the spectrum. This can solve the overproduction of γ-rays by suppressing the high-energy end of the emitting particle population. Furthermore, we show that cooling in the EC/CMB model predicts a new class of extended jets that are bright in X-rays but silent in the radio and optical bands. These jets are more likely to lie at intermediate redshifts and would have been missed in all previous X-ray surveys due to selection effects.

Effects on the CMB from magnetic field dissipation before recombination

Science.gov (United States)

Kunze, Kerstin E.

2017-09-01

Magnetic fields present before decoupling are damped due to radiative viscosity. This energy injection affects the thermal and ionization history of the cosmic plasma. The implications for the CMB anisotropies and polarization are investigated for different parameter choices of a nonhelical stochastic magnetic field. Assuming a Gaussian smoothing scale determined by the magnetic damping wave number at recombination, it is found that magnetic fields with present-day strength less than 0.1 nG and negative magnetic spectral indices have a sizable effect on the CMB temperature anisotropies and polarization.

CMB constraints on β-exponential inflationary models

Science.gov (United States)

Santos, M. A.; Benetti, M.; Alcaniz, J. S.; Brito, F. A.; Silva, R.

2018-03-01

We analyze a class of generalized inflationary models proposed in ref. [1], known as β-exponential inflation. We show that this kind of potential can arise in the context of brane cosmology, where the field describing the size of the extra-dimension is interpreted as the inflaton. We discuss the observational viability of this class of model in light of the latest Cosmic Microwave Background (CMB) data from the Planck Collaboration through a Bayesian analysis, and impose tight constraints on the model parameters. We find that the CMB data alone prefer weakly the minimal standard model (ΛCDM) over the β-exponential inflation. However, when current local measurements of the Hubble parameter, H0, are considered, the β-inflation model is moderately preferred over the ΛCDM cosmology, making the study of this class of inflationary models interesting in the context of the current H0 tension.

Constraining the evolution of the CMB temperature with SZ measurements from Planck data

Energy Technology Data Exchange (ETDEWEB)

Luzzi, G.; Petris, M. De; Lamagna, L. [Dept. of Physics, Sapienza, University of Rome, Piazzale Aldo Moro 2, Rome, I-00185 Italy (Italy); Génova-Santos, R.T. [Instituto de Astrofísica de Canarias, C/Vía Láctea s/n, La Laguna, Tenerife (Spain); Martins, C.J.A.P., E-mail: gemma.luzzi@roma1.infn.it, E-mail: rgs@iac.es, E-mail: carlos.martins@astro.up.pt, E-mail: marco.depetris@roma1.infn.it, E-mail: luca.lamagna@roma1.infn.it [Centro de Astrofísica, Universidade do Porto, Rua das Estrelas, Porto, 4150-762 Portugal (Portugal)

2015-09-01

The CMB temperature-redshift relation, T{sub CMB}(z)=T{sub 0}(1+z), is a key prediction of the standard cosmology but is violated in many non-standard models. Constraining possible deviations from this law is an effective way to test the ΛCDM paradigm and to search for hints of new physics. We have determined T{sub CMB}(z), with a precision up to 3%, for a subsample (103 clusters) of the Planck SZ cluster catalog, at redshifts in the range 0.01–0.94, using measurements of the spectrum of the Sunyaev-Zel'dovich (SZ) effect obtained from Planck temperature maps at frequencies from 70 to 353 GHz. The method adopted to provide individual determinations of T{sub CMB}(z) at cluster redshift relies on the use of SZ intensity change, Δ I{sub SZ}(ν) at different frequencies and on a Monte Carlo Markov chain approach. By applying this method to the sample of 103 clusters, we limit possible deviations of the form T{sub CMB}(z)=T{sub 0}(1+z){sup 1−β} to be β= 0.012 ± 0.016, at 1σ uncertainty, consistent with the prediction of the standard model. Combining these measurements with previously published results, we get β=0.013±0.011.

CMB anisotropies at all orders: the non-linear Sachs-Wolfe formula

OpenAIRE

Roldan, Omar

2017-01-01

We obtain the non-linear generalization of the Sachs-Wolfe + integrated Sachs-Wolfe (ISW) formula describing the CMB temperature anisotropies. Our formula is valid at all orders in perturbation theory, is also valid in all gauges and includes scalar, vector and tensor modes. A direct consequence of our results is that the maps of the logarithmic temperature anisotropies are much cleaner than the usual CMB maps, because they automatically remove many secondary anisotropies. This can for instan...

CMB aberration and Doppler effects as a source of hemispherical asymmetries

International Nuclear Information System (INIS)

Notari, Alessio; Quartin, Miguel; Catena, Riccardo

2014-01-01

Our peculiar motion with respect to the CMB rest frame represents a preferred direction in the observed CMB sky since it induces an apparent deflection of the observed CMB photons (aberration) and a shift in their frequency (Doppler). Both effects distort the multipoles a ℓm 's at all ℓ's. Such effects are real as it has been recently measured for the first time by Planck according to what was forecast in some recent papers. However, the common lore when estimating a power spectrum from CMB is to consider that Doppler affects only the ℓ = 1 multipole, neglecting any other corrections. In this work we use simulations of the CMB sky in a boosted frame with a peculiar velocity β≡v/c = 1.23 × 10 −3 in order to assess the impact of such effect on power spectrum estimations in different regions of the sky. We show that the boost induces a north-south asymmetry in the power spectrum which is highly significant and non-negligible, of about (0.58±0.10)% for half-sky cuts when going up to ℓ ≈ 2500. We suggest that these effects are relevant and may account for some of the north-south asymmetries seen in the Planck data, being especially important at small scales. Finally we analyze the particular case of the ACT experiment, which observed only a small fraction of the sky and show that it suffers a bias of about 1% on the power spectrum and of similar size on some cosmological parameters: for example the position of the peaks shifts by 0.5% and the overall amplitude of the spectrum is about 0.4% lower than a full-sky case

Echoes of inflationary first-order phase transitions in the CMB

Directory of Open Access Journals (Sweden)

Hongliang Jiang

2017-02-01

Full Text Available Cosmological phase transitions (CPTs, such as the Grand Unified Theory (GUT and the electroweak (EW ones, play a significant role in both particle physics and cosmology. In this letter, we propose to probe the first-order CPTs, by detecting gravitational waves (GWs which are generated during the phase transitions through the cosmic microwave background (CMB. If happened around the inflation era, the first-order CPTs may yield low-frequency GWs due to bubble dynamics, leaving imprints on the CMB. In contrast to the nearly scale-invariant primordial GWs caused by vacuum fluctuation, these bubble-generated GWs are scale dependent and have non-trivial B-mode spectra. If decoupled from inflaton, the EWPT during inflation may serve as a probe for the one after reheating where the baryon asymmetry could be generated via EW baryogenesis (EWBG. The CMB thus provides a potential way to test the feasibility of the EWBG, complementary to the collider measurements of Higgs potential and the direct detection of GWs generated during EWPT.

Hidden in the background: a local approach to CMB anomalies

Energy Technology Data Exchange (ETDEWEB)

Sánchez, Juan C. Bueno, E-mail: juan.c.bueno@correounivalle.edu.co [Centro de Investigaciones en Ciencias Básicas y Aplicadas, Universidad Antonio Nariño, Cra 3 Este # 47A-15, Bogotá D.C. 110231 (Colombia)

2016-09-01

We investigate a framework aiming to provide a common origin for the large-angle anomalies detected in the Cosmic Microwave Background (CMB), which are hypothesized as the result of the statistical inhomogeneity developed by different isocurvature fields of mass m ∼ H present during inflation. The inhomogeneity arises as the combined effect of ( i ) the initial conditions for isocurvature fields (obtained after a fast-roll stage finishing many e -foldings before cosmological scales exit the horizon), ( ii ) their inflationary fluctuations and ( iii ) their coupling to other degrees of freedom. Our case of interest is when these fields (interpreted as the precursors of large-angle anomalies) leave an observable imprint only in isolated patches of the Universe. When the latter intersect the last scattering surface, such imprints arise in the CMB. Nevertheless, due to their statistically inhomogeneous nature, these imprints are difficult to detect, for they become hidden in the background similarly to the Cold Spot. We then compute the probability that a single isocurvature field becomes inhomogeneous at the end of inflation and find that, if the appropriate conditions are given (which depend exclusively on the preexisting fast-roll stage), this probability is at the percent level. Finally, we discuss several mechanisms (including the curvaton and the inhomogeneous reheating) to investigate whether an initial statistically inhomogeneous isocurvature field fluctuation might give rise to some of the observed anomalies. In particular, we focus on the Cold Spot, the power deficit at low multipoles and the breaking of statistical isotropy.

Effects on the CMB from compactification before inflation

Energy Technology Data Exchange (ETDEWEB)

Kontou, Eleni-Alexandra [Physics Program, Bard College, 30 Campus Rd, Annandale-on-Hudson, NY 12504 (United States); Blanco-Pillado, Jose J. [IKERBASQUE, Basque Foundation for Science, 48011, Bilbao (Spain); Hertzberg, Mark P.; Masoumi, Ali, E-mail: elenikontou@cosmos.phy.tufts.edu, E-mail: josejuan.blanco@ehu.es, E-mail: mark.hertzberg@tufts.edu, E-mail: ali@cosmos.phy.tufts.edu [Institute of Cosmology, Department of Physics and Astronomy, Tufts University, Medford, MA 02155 (United States)

2017-04-01

Many theories beyond the Standard Model include extra dimensions, though these have yet to be directly observed. In this work we consider the possibility of a compactification mechanism which both allows extra dimensions and is compatible with current observations. This compactification is predicted to leave a signature on the CMB by altering the amplitude of the low l multipoles, dependent on the amount of inflation. Recently discovered CMB anomalies at low multipoles may be evidence for this. In our model we assume the spacetime is the product of a four-dimensional spacetime and flat extra dimensions. Before the compactification, both the four-dimensional spacetime and the extra dimensions can either be expanding or contracting independently. Taking into account physical constraints, we explore the observational consequences and the plausibility of these different models.

From Cavendish to PLANCK: Constraining Newton's gravitational constant with CMB temperature and polarization anisotropy

International Nuclear Information System (INIS)

Galli, Silvia; Melchiorri, Alessandro; Smoot, George F.; Zahn, Oliver

2009-01-01

We present new constraints on cosmic variations of Newton's gravitational constant by making use of the latest CMB data from WMAP, BOOMERANG, CBI and ACBAR experiments and independent constraints coming from big bang nucleosynthesis. We found that current CMB data provide constraints at the ∼10% level, that can be improved to ∼3% by including big bang nucleosynthesis data. We show that future data expected from the Planck satellite could constrain G at the ∼1.5% level while an ultimate, cosmic variance limited, CMB experiment could reach a precision of about 0.4%, competitive with current laboratory measurements.

CMB constraints on the inflaton couplings and reheating temperature in α-attractor inflation

Science.gov (United States)

Drewes, Marco; Kang, Jin U.; Mun, Ui Ri

2017-11-01

We study reheating in α-attractor models of inflation in which the inflaton couples to other scalars or fermions. We show that the parameter space contains viable regions in which the inflaton couplings to radiation can be determined from the properties of CMB temperature fluctuations, in particular the spectral index. This may be the only way to measure these fundamental microphysical parameters, which shaped the universe by setting the initial temperature of the hot big bang and contain important information about the embedding of a given model of inflation into a more fundamental theory of physics. The method can be applied to other models of single field inflation.

Architectures and assessment of next-generation CMB polarization instruments

Data.gov (United States)

National Aeronautics and Space Administration — Cosmological inflation predicts a background of gravitational waves that imprint a characteristic polarized pattern on the CMB. This signal is degraded by...

On the Origins of the CMB: Insight from the COBE, WMAP, and Relikt-1 Satellites

Directory of Open Access Journals (Sweden)

Robitaille P.-M.

2007-01-01

Full Text Available The powerful “Cosmic Microwave Background (CMB” signal currently associated with the origins of the Universe is examined from a historical perspective and relative to the experimental context in which it was measured. Results from the COBE satellite are reviewed, with particular emphasis on the systematic error observed in determining the CMB temperature. The nature of the microwave signal emanating from the oceans is also discussed. From this analysis, it is demonstrated that it is improper for the COBE team to model the Earth as a 285 K blackbody source. The assignment of temperatures to objects that fail to meet the requirements set forth in Kirchhoff’s law constitutes a serious overextension of the laws of thermal emission. Using this evidence, and the general rule that powerful signals are associated with proximal sources, the CMB monopole signal is reassigned to the oceans. In turn, through the analysis of COBE, WMAP, and Relikt-1 data, the dipole signal is attributed to motion through a much weaker microwave field present both at the position of the Earth and at the second Lagrange point.

Thermodynamics of SU(2 quantum Yang-Mills theory and CMB anomalies

Directory of Open Access Journals (Sweden)

Hofmann Ralf

2014-04-01

Full Text Available A brief review of effective SU(2 Yang-Mills thermodynamics in the deconfining phase is given, including the construction of the thermal ground-state estimate in terms of an inert, adjoint scalar field φ, based on non-propagating (antiselfdual field configurations of topological charge unity. We also discuss kinematic constraints on interacting propagating gauge fields implied by the according spatial coarse-graining, and we explain why the screening physics of an SU(2 photon is subject to an electric-magnetically dual interpretation. This argument relies on the fact that only (anticalorons of scale parameter ρ ∼ |φ|−1 contribute to the coarse-graining required for thermal-ground-state emergence at temperature T. Thus, use of the effective gauge coupling e in the (anticaloron action is justified, yielding the value ħ for the latter at almost all temperatures. As a consequence, the indeterministic transition of initial to final plane waves caused by an effective, pointlike vertex is fundamentally mediated in Euclidean time by a single (anticaloron being part of the thermal ground state. Next, we elucidate how a low-frequency excess of line temperature in the Cosmic Microwave Background (CMB determines the value of the critical temperature of the deconfining-preconfining phase transition of an SU(2 Yang-Mills theory postulated to describe photon propagation, and we describe how, starting at a redshift of about unity, SU(2 photons collectively work 3D temperature depressions into the CMB. Upon projection along a line of sight, a given depression influences the present CMB sky in a cosmologically local way, possibly explaining the large-angle anomalies confirmed recently by the Planck collaboration. Finally, six relativistic polarisations residing in the SU(2 vector modes roughly match the number of degrees of freedom in cosmic neutrinos (Planck which would disqualify the latter as radiation. Indeed, if interpreted as single center

Thermodynamics of SU(2) quantum Yang-Mills theory and CMB anomalies

Science.gov (United States)

Hofmann, Ralf

2014-04-01

A brief review of effective SU(2) Yang-Mills thermodynamics in the deconfining phase is given, including the construction of the thermal ground-state estimate in terms of an inert, adjoint scalar field φ, based on non-propagating (anti)selfdual field configurations of topological charge unity. We also discuss kinematic constraints on interacting propagating gauge fields implied by the according spatial coarse-graining, and we explain why the screening physics of an SU(2) photon is subject to an electric-magnetically dual interpretation. This argument relies on the fact that only (anti)calorons of scale parameter ρ ˜ |φ|-1 contribute to the coarse-graining required for thermal-ground-state emergence at temperature T. Thus, use of the effective gauge coupling e in the (anti)caloron action is justified, yielding the value ħ for the latter at almost all temperatures. As a consequence, the indeterministic transition of initial to final plane waves caused by an effective, pointlike vertex is fundamentally mediated in Euclidean time by a single (anti)caloron being part of the thermal ground state. Next, we elucidate how a low-frequency excess of line temperature in the Cosmic Microwave Background (CMB) determines the value of the critical temperature of the deconfining-preconfining phase transition of an SU(2) Yang-Mills theory postulated to describe photon propagation, and we describe how, starting at a redshift of about unity, SU(2) photons collectively work 3D temperature depressions into the CMB. Upon projection along a line of sight, a given depression influences the present CMB sky in a cosmologically local way, possibly explaining the large-angle anomalies confirmed recently by the Planck collaboration. Finally, six relativistic polarisations residing in the SU(2) vector modes roughly match the number of degrees of freedom in cosmic neutrinos (Planck) which would disqualify the latter as radiation. Indeed, if interpreted as single center-vortex loops in

Exploring cosmic origins with CORE: Gravitational lensing of the CMB

Science.gov (United States)

Challinor, A.; Allison, R.; Carron, J.; Errard, J.; Feeney, S.; Kitching, T.; Lesgourgues, J.; Lewis, A.; Zubeldía, Í.; Achucarro, A.; Ade, P.; Ashdown, M.; Ballardini, M.; Banday, A. J.; Banerji, R.; Bartlett, J.; Bartolo, N.; Basak, S.; Baumann, D.; Bersanelli, M.; Bonaldi, A.; Bonato, M.; Borrill, J.; Bouchet, F.; Boulanger, F.; Brinckmann, T.; Bucher, M.; Burigana, C.; Buzzelli, A.; Cai, Z.-Y.; Calvo, M.; Carvalho, C.-S.; Castellano, G.; Chluba, J.; Clesse, S.; Colantoni, I.; Coppolecchia, A.; Crook, M.; d'Alessandro, G.; de Bernardis, P.; de Gasperis, G.; De Zotti, G.; Delabrouille, J.; Di Valentino, E.; Diego, J.-M.; Fernandez-Cobos, R.; Ferraro, S.; Finelli, F.; Forastieri, F.; Galli, S.; Genova-Santos, R.; Gerbino, M.; González-Nuevo, J.; Grandis, S.; Greenslade, J.; Hagstotz, S.; Hanany, S.; Handley, W.; Hernandez-Monteagudo, C.; Hervías-Caimapo, C.; Hills, M.; Hivon, E.; Kiiveri, K.; Kisner, T.; Kunz, M.; Kurki-Suonio, H.; Lamagna, L.; Lasenby, A.; Lattanzi, M.; Liguori, M.; Lindholm, V.; López-Caniego, M.; Luzzi, G.; Maffei, B.; Martinez-González, E.; Martins, C. J. A. P.; Masi, S.; Matarrese, S.; McCarthy, D.; Melchiorri, A.; Melin, J.-B.; Molinari, D.; Monfardini, A.; Natoli, P.; Negrello, M.; Notari, A.; Paiella, A.; Paoletti, D.; Patanchon, G.; Piat, M.; Pisano, G.; Polastri, L.; Polenta, G.; Pollo, A.; Poulin, V.; Quartin, M.; Remazeilles, M.; Roman, M.; Rubino-Martin, J.-A.; Salvati, L.; Tartari, A.; Tomasi, M.; Tramonte, D.; Trappe, N.; Trombetti, T.; Tucker, C.; Valiviita, J.; Van de Weijgaert, R.; van Tent, B.; Vennin, V.; Vielva, P.; Vittorio, N.; Young, K.; Zannoni, M.

2018-04-01

Lensing of the cosmic microwave background (CMB) is now a well-developed probe of the clustering of the large-scale mass distribution over a broad range of redshifts. By exploiting the non-Gaussian imprints of lensing in the polarization of the CMB, the CORE mission will allow production of a clean map of the lensing deflections over nearly the full-sky. The number of high-S/N modes in this map will exceed current CMB lensing maps by a factor of 40, and the measurement will be sample-variance limited on all scales where linear theory is valid. Here, we summarise this mission product and discuss the science that will follow from its power spectrum and the cross-correlation with other clustering data. For example, the summed mass of neutrinos will be determined to an accuracy of 17 meV combining CORE lensing and CMB two-point information with contemporaneous measurements of the baryon acoustic oscillation feature in the clustering of galaxies, three times smaller than the minimum total mass allowed by neutrino oscillation measurements. Lensing has applications across many other science goals of CORE, including the search for B-mode polarization from primordial gravitational waves. Here, lens-induced B-modes will dominate over instrument noise, limiting constraints on the power spectrum amplitude of primordial gravitational waves. With lensing reconstructed by CORE, one can "delens" the observed polarization internally, reducing the lensing B-mode power by 60 %. This can be improved to 70 % by combining lensing and measurements of the cosmic infrared background from CORE, leading to an improvement of a factor of 2.5 in the error on the amplitude of primordial gravitational waves compared to no delensing (in the null hypothesis of no primordial B-modes). Lensing measurements from CORE will allow calibration of the halo masses of the tens of thousands of galaxy clusters that it will find, with constraints dominated by the clean polarization-based estimators. The 19

A correlation between the cosmic microwave background and large-scale structure in the Universe.

Science.gov (United States)

Boughn, Stephen; Crittenden, Robert

2004-01-01

Observations of distant supernovae and the fluctuations in the cosmic microwave background (CMB) indicate that the expansion of the Universe may be accelerating under the action of a 'cosmological constant' or some other form of 'dark energy'. This dark energy now appears to dominate the Universe and not only alters its expansion rate, but also affects the evolution of fluctuations in the density of matter, slowing down the gravitational collapse of material (into, for example, clusters of galaxies) in recent times. Additional fluctuations in the temperature of CMB photons are induced as they pass through large-scale structures and these fluctuations are necessarily correlated with the distribution of relatively nearby matter. Here we report the detection of correlations between recent CMB data and two probes of large-scale structure: the X-ray background and the distribution of radio galaxies. These correlations are consistent with those predicted by dark energy, indicating that we are seeing the imprint of dark energy on the growth of structure in the Universe.

Global universe anisotropy probed by the alignment of structures in the cosmic microwave background.

Science.gov (United States)

Wiaux, Y; Vielva, P; Martínez-González, E; Vandergheynst, P

2006-04-21

We question the global universe isotropy by probing the alignment of local structures in the cosmic microwave background (CMB) radiation. The original method proposed relies on a steerable wavelet decomposition of the CMB signal on the sphere. The analysis of the first-year Wilkinson Microwave Anisotropy Probe data identifies a mean preferred plane with a normal direction close to the CMB dipole axis, and a mean preferred direction in this plane, very close to the ecliptic poles axis. Previous statistical anisotropy results are thereby synthesized, but further analyses are still required to establish their origin.

SPIDER: CMB Polarimetry from the Edge of Space

Energy Technology Data Exchange (ETDEWEB)

Gualtieri, R.; et al.

2017-11-28

SPIDER is a balloon-borne instrument designed to map the polarization of the millimeter-wave sky at large angular scales. SPIDER targets the B-mode signature of primordial gravitational waves in the cosmic microwave background (CMB), with a focus on mapping a large sky area with high fidelity at multiple frequencies. SPIDER's first longduration balloon (LDB) flight in January 2015 deployed a total of 2400 antenna-coupled Transition Edge Sensors (TESs) at 90 GHz and 150 GHz. In this work we review the design and in-flight performance of the SPIDER instrument, with a particular focus on the measured performance of the detectors and instrument in a space-like loading and radiation environment. SPIDER's second flight in December 2018 will incorporate payload upgrades and new receivers to map the sky at 285 GHz, providing valuable information for cleaning polarized dust emission from CMB maps.

Gravitational waves in axion inflation: implications for CMB and small-scales interferometer measurements

Science.gov (United States)

Unal, Caner; Peloso, Marco; Sorbo, Lorenzo; Garcia-Bellido, Juan

2017-01-01

A strong experimental effort is ongoing to detect the primordial gravitational waves (GW) generated during inflation from their impact on the Cosmic Microwave Background (CMB). This effort is motivated by the direct relation between the amplitude of GW signal and the energy scale of inflation, in the standard case of GW production from vacuum. I will discuss the robustness of this relation and the conditions under which particle production mechanisms during inflation can generate a stronger GW signal than the vacuum one. I will present a concrete model employing a coupling between a rolling axion and a gauge field, that can produce a detectable GW signal for an arbitrarily small inflation scale, respecting bounds from back-reaction, perturbativity, and the gaussianity of the measured density perturbations. I will show how the GW produced by this mechanism can be distinguished from the vacuum ones by their spectral dependence and statistical properties. I will finally discuss the possibility of detecting an inflationary GW signal at terrestrial (AdvLIGO) and space (LISA) interferometers. Such experiments are sensitive to the modes much smaller than the ones corresponding to CMB and Large Scale Structure, presenting a unique observational window on the final stages of inflation. The work of C.U. is s supported by a Doctoral Dissertation Fellowship from the Graduate School of the University of Minnesota.

The Diffuse Light of the Universe

Science.gov (United States)

Bonnet-Bidaud, Jean-Marc

2017-06-01

In 1965, the discovery of a new type of uniform radiation, located between radiowaves and infrared light, was accidental. Known today as Cosmic Microwave background (CMB), this diffuse radiation is commonly interpreted as a fossil light released in an early hot and dense universe and constitutes today the main 'pilar' of the big bang cosmology. Considerable efforts have been devoted to derive fundamental cosmological parameters from the characteristics of this radiation that led to a surprising universe that is shaped by at least three major unknown components: inflation, dark matter and dark energy. This is an important weakness of the present consensus cosmological model that justifies raising several questions on the CMB interpretation. Can we consider its cosmological nature as undisputable? Do other possible interpretations exist in the context of other cosmological theories or simply as a result of other physical mechanisms that could account for it? In an effort to questioning the validity of scientific hypotheses and the under-determination of theories compared to observations, we examine here the difficulties that still exist on the interpretation of this diffuse radiation and explore other proposed tracks to explain its origin. We discuss previous historical concepts of diffuse radiation before and after the CMB discovery and underline the limit of our present understanding.

Fermi Non-detections of Four X-Ray Jet Sources and Implications for the IC/CMB Mechanism

Science.gov (United States)

Breiding, Peter; Meyer, Eileen T.; Georganopoulos, Markos; Keenan, M. E.; DeNigris, N. S.; Hewitt, Jennifer

2017-11-01

Since its launch in 1999, the Chandra X-ray observatory has discovered several dozen X-ray jets associated with powerful quasars. In many cases, the X-ray spectrum is hard and appears to come from a second spectral component. The most popular explanation for the kpc-scale X-ray emission in these cases has been inverse-Compton (IC) scattering of Cosmic Microwave Background (CMB) photons by relativistic electrons in the jet (the IC/CMB model). Requiring the IC/CMB emission to reproduce the observed X-ray flux density inevitably predicts a high level of gamma-ray emission, which should be detectable with the Fermi Large Area Telescope (LAT). In previous work, we found that gamma-ray upper limits from the large-scale jets of 3C 273 and PKS 0637-752 violate the predictions of the IC/CMB model. Here, we present Fermi/LAT flux density upper limits for the X-ray jets of four additional sources: PKS 1136-135, PKS 1229-021, PKS 1354+195, and PKS 2209+080. We show that these limits violate the IC/CMB predictions at a very high significance level. We also present new Hubble Space Telescope observations of the quasar PKS 2209+080 showing a newly detected optical jet, and Atacama Large Millimeter/submillimeter Array band 3 and 6 observations of all four sources, which provide key constraints on the spectral shape that enable us to rule out the IC/CMB model.

Dark Matter in the Universe and in the Galaxy

Science.gov (United States)

Kamionkowski, Marc

1999-01-01

During the past four years, Prof. Kamionkowski and collaborators have made progress in research on the nature and distribution of dark-matter in the Universe and in the Galaxy, and on related topics in astrophysics and cosmology. We have made progress on research on the cosmic microwave background, large-scale structure, issues related to particle dark matter, and the gamma-ray-burst enigma. A significant fraction of the research supported by this ATP has been on the cosmic microwave background (CMB). Prof. Kamionkowski and collaborators showed how the polarization of the CMB could be used to detect long-wavelength gravitational waves, such as those produced by inflation. With Kosowsky, Prof. Kamionkowski calculated the amplitude of a stochastic gravitational-wave background that could be detected for a satellite experiment of a given sensitivity and angular resolution. They showed that polarization should improve the sensitivity oa MAP to these gravity waves, and that the Planck Surveyor should do even better. Prof. Kamionkowski, Caldwell, and a student calculated and illustrated the CMB temperature/polarization pattern produced by a single plane-wave gravitational wave. They calculated the amplitude of such a wave that would be detectable with MAP and Planck, and compared that with the sensitivity of traditional gravitational-wave detectors like LIGO and LISA. With Lue and Wang, the PI showed how parity violation from new high-energy physics could conceivably give rise to an observable signature in the CMB polarization. With Loeb, Prof. Kamionkowski showed how measurement of the polarization of CMB photons scattered by hot gas in a cluster could be used to determine the quadrupole moment of the CMB incident on that cluster. Prof. Kamionkowski and Jaffe calculated the amplitude of secondary anisotropies produced by scattering of CMB photons from reionized regions. Research has also been carried out on probing the large-scale distribution of mass in the Universe

PMF5.0 vs. CMB8.2: An inter-comparison study based on the new European SPECIEUROPE database

Science.gov (United States)

Bove, Maria Chiara; Massabò, Dario; Prati, Paolo

2018-03-01

Receptor Models are tools widely adopted in source apportionment studies. We describe here an experiment in which we integrated two different approaches, i.e. Positive Matrix Factorization (PMF) and Chemical Mass Balance (CMB) to apportion a set of PM10 (i.e. Particulate Matter with aerodynamic diameter lower than 10 μm) concentration values. The study was performed in the city of Genoa (Italy): a sampling campaign was carried out collecting daily PM10 samples for about two months in an urban background site. PM10 was collected on Quartz fiber filters by a low-volume sampler. A quite complete speciation of PM samples was obtained via Energy Dispersive-X Ray Fluorescence (ED-XRF, for elements), Ionic Chromatography (IC, for major ions and levoglucosan), thermo-optical Analysis (TOT, for organic and elemental carbon). The chemical analyses provided the input database for source apportionment by both PMF and CMB. Source profiles were directly calculated from the input data by PMF while in the CMB runs they were first calculated by averaging the profiles of similar sources collected in the European database SPECIEUROPE. Differences between the two receptor models emerged in particular with PM10 sources linked to very local processes. For this reason, PMF source profiles were adopted in refined CMB runs thus testing a new hybrid approach. Finally, PMF and the "tuned" CMB showed a better agreement even if some discrepancies could not completely been resolved. In this work, we compared the results coming from the last available PMF and CMB versions applied on a set of PM10 samples. Input profiles used in CMB analysis were obtained by averaging the profiles of the new European SPECIEUROPE database. The main differences between PMF and CMB results were linked to very local processes: we obtained the best solution by integrating the two different approaches with the implementation of some output PMF profiles to CMB runs.

Constraining the CMB optical depth through the dispersion measure of cosmological radio transients

International Nuclear Information System (INIS)

Fialkov, A.; Loeb, A.

2016-01-01

The dispersion measure of extragalactic radio transients can be used to measure the column density of free electrons in the intergalactic medium. The same electrons also scatter the Cosmic Microwave Background (CMB) photons, affecting precision measurements of cosmological parameters. We explore the connection between the dispersion measure of radio transients existing during the Epoch of Reionization (EoR) and the total optical depth for the CMB showing that the existence of such transients would provide a new sensitive probe of the CMB optical depth. As an example, we consider the population of FRBs. Assuming they exist during the EoR, we show that: (i) such sources can probe the reionization history by measuring the optical depth to sub-percent accuracy, and (ii) they can be detected with high significance by an instrument such as the Square Kilometer Array.

Constraining the CMB optical depth through the dispersion measure of cosmological radio transients

Energy Technology Data Exchange (ETDEWEB)

Fialkov, A.; Loeb, A., E-mail: anastasia.fialkov@cfa.harvard.edu, E-mail: aloeb@cfa.harvard.edu [Institute for Teory and Computation, Harvard University, 60 Garden Street, MS-51, Cambridge, MA, 02138 (United States)

2016-05-01

The dispersion measure of extragalactic radio transients can be used to measure the column density of free electrons in the intergalactic medium. The same electrons also scatter the Cosmic Microwave Background (CMB) photons, affecting precision measurements of cosmological parameters. We explore the connection between the dispersion measure of radio transients existing during the Epoch of Reionization (EoR) and the total optical depth for the CMB showing that the existence of such transients would provide a new sensitive probe of the CMB optical depth. As an example, we consider the population of FRBs. Assuming they exist during the EoR, we show that: (i) such sources can probe the reionization history by measuring the optical depth to sub-percent accuracy, and (ii) they can be detected with high significance by an instrument such as the Square Kilometer Array.

Development of Optics and Detectors for Advanced CMB Polarization Measurements

Data.gov (United States)

National Aeronautics and Space Administration — Measurements of the cosmic microwave background (CMB) have been essential to the development of modern cosmology. Future observations will provide cosmological...

CMB-8 material balance system

International Nuclear Information System (INIS)

Langner, D.; Canada, T.; Ensslin, N.; Atwell, T.; Baxman, H.; Cowder, L.; Speir, L.; Lyssel, T.V.; Sampson, T.

1980-08-01

We describe the automated nondestructive assay (NDA) system installed at the Los Alamos Scientific Laboratory (LASL) Group CMB-8 uranium recovery facility. A random driver (RD) is used to measure the 235 U content of various solids while a uranium solution assay system (USAS) measures the 235 U or total uranium content of solutions over a concentration range of a few ppM to 400 g/l. Both instruments are interfaced to and controlled by a single minicomputer. The measurement principles, mechanical specifications, system software description, and operational instructions are described

Cysteine-mediated gene expression and characterization of the CmbR regulon in Streptococcus pneumoniae

Directory of Open Access Journals (Sweden)

Muhammad Afzal

2016-12-01

Full Text Available In this study, we investigated the transcriptomic response of Streptococcus pneumoniae D39 to cysteine. Transcriptome comparison of the D39 wild-type strain grown at a restricted concentration of cysteine (0.03 mM to one grown at a high concentration of cysteine (50 mM in chemically-define medium (CDM revealed elevated expression of various genes/operons, i.e. spd-0150, metQ, spd-0431, metEF, gshT, spd-0618, fhs, tcyB, metB-csd, metA, spd-1898, yvdE, and cysK, likely to be involved in the transport and utilization of cysteine and/or methionine. Microarray-based data were further confirmed by quantitative RT-PCR. Promoter lacZ-fusion studies and quantitative RT-PCR data showed that the transcriptional regulator CmbR acts as a transcriptional repressor of spd-0150, metEF, gshT, spd-0618, tcyB, metA, and yvdE, putatively involved in cysteine uptake and utilization. The operator site of CmbR in the promoter regions of CmbR-regulated genes is predicted and confirmed by mutating or deleting CmbR operator sites from the promoter regions of these genes.

Compensation for large tensor modes with iso-curvature perturbations in CMB anisotropies

Energy Technology Data Exchange (ETDEWEB)

Kawasaki, Masahiro; Yokoyama, Shuichiro, E-mail: kawasaki@icrr.u-tokyo.ac.jp, E-mail: shu@icrr.u-tokyo.ac.jp [Institute for Cosmic Ray Research, University of Tokyo, Kashiwa 277-8582 (Japan)

2014-05-01

Recently, BICEP2 has reported the large tensor-to-scalar ratio r = 0.2{sup +0.07}{sub −0.05} from the observation of the cosmic microwave background (CMB) B-mode at degree-scales. Since tensor modes induce not only CMB B-mode but also the temperature fluctuations on large scales, to realize the consistent temperature fluctuations with the Planck result we should consider suppression of scalar perturbations on corresponding large scales. To realize such a suppression, we consider anti-correlated iso-curvature perturbations which could be realized in the simple curvaton model.

On the impact of large angle CMB polarization data on cosmological parameters

Energy Technology Data Exchange (ETDEWEB)

Lattanzi, Massimiliano; Mandolesi, Nazzareno; Natoli, Paolo [Dipartimento di Fisica e Scienze della Terra, Università di Ferrara, Via Giuseppe Saragat 1, I-44122 Ferrara (Italy); Burigana, Carlo; Gruppuso, Alessandro; Trombetti, Tiziana [Istituto Nazionale di Astrofisica, Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, Via Piero Gobetti 101, I-40129 Bologna (Italy); Gerbino, Martina [The Oskar Klein Centre for Cosmoparticle Physics, Department of Physics, Stockholm University, AlbaNova, SE-106 91 Stockholm (Sweden); Polenta, Gianluca [Agenzia Spaziale Italiana Science Data Center, Via del Politecnico snc, 00133, Roma (Italy); Salvati, Laura, E-mail: lattanzi@fe.infn.it, E-mail: burigana@iasfbo.inaf.it, E-mail: martina.gerbino@fysik.su.se, E-mail: gruppuso@iasfbo.inaf.it, E-mail: nazzareno.mandolesi@unife.it, E-mail: paolo.natoli@unife.it, E-mail: gianluca.polenta@asdc.asi.it, E-mail: laura.salvati@ias.u-psud.fr, E-mail: trombetti@iasfbo.inaf.it [Dipartimento di Fisica, Università La Sapienza, Piazzale Aldo Moro 2, I-00185 Roma (Italy)

2017-02-01

We study the impact of the large-angle CMB polarization datasets publicly released by the WMAP and Planck satellites on the estimation of cosmological parameters of the ΛCDM model. To complement large-angle polarization, we consider the high resolution (or 'high-ℓ') CMB datasets from either WMAP or Planck as well as CMB lensing as traced by Planck 's measured four point correlation function. In the case of WMAP, we compute the large-angle polarization likelihood starting over from low resolution frequency maps and their covariance matrices, and perform our own foreground mitigation technique, which includes as a possible alternative Planck 353 GHz data to trace polarized dust. We find that the latter choice induces a downward shift in the optical depth τ, roughly of order 2σ, robust to the choice of the complementary high resolution dataset. When the Planck 353 GHz is consistently used to minimize polarized dust emission, WMAP and Planck 70 GHz large-angle polarization data are in remarkable agreement: by combining them we find τ = 0.066 {sup +0.012}{sub −0.013}, again very stable against the particular choice for high-ℓ data. We find that the amplitude of primordial fluctuations A {sub s} , notoriously degenerate with τ, is the parameter second most affected by the assumptions on polarized dust removal, but the other parameters are also affected, typically between 0.5 and 1σ. In particular, cleaning dust with Planck 's 353 GHz data imposes a 1σ downward shift in the value of the Hubble constant H {sub 0}, significantly contributing to the tension reported between CMB based and direct measurements of the present expansion rate. On the other hand, we find that the appearance of the so-called low ℓ anomaly, a well-known tension between the high- and low-resolution CMB anisotropy amplitude, is not significantly affected by the details of large-angle polarization, or by the particular high-ℓ dataset employed.

The ethics of patenting human embryonic stem cells.

Science.gov (United States)

Chapman, Audrey R

2009-09-01

Just as human embryonic stem cell research has generated controversy about the uses of human embryos for research and therapeutic applications, human embryonic stem cell patents raise fundamental ethical issues. The United States Patent and Trademark Office has granted foundational patents, including a composition of matter (or product) patent to the Wisconsin Alumni Research Foundation (WARF), the University of Wisconsin-Madison's intellectual property office. In contrast, the European Patent Office rejected the same WARF patent application for ethical reasons. This article assesses the appropriateness of these patents placing the discussion in the context of the deontological and consequentialist ethical issues related to human embryonic stem cell patenting. It advocates for a patent system that explicitly takes ethical factors into account and explores options for new types of intellectual property arrangements consistent with ethical concerns.

The cross-correlation of the CMB polarization and the 21-cm line fluctuations from cosmic reionization

NARCIS (Netherlands)

Tashiro, Hiroyuki; Aghanim, Nabila; Langer, Mathieu; Douspis, Marian; Zaroubi, Saleem

2008-01-01

The cosmic microwave background (CMB) polarization and the 21-cm line fluctuations are powerful probes of cosmological reionization. We study how the cross-correlation between the CMB polarization (E modes) and the 21-cm line fluctuations can be used to gain further understanding of the reionization

Constraints on the CMB temperature-redshift dependence from SZ and distance measurements

Energy Technology Data Exchange (ETDEWEB)

Avgoustidis, A. [School of Physics and Astronomy, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom); Luzzi, G. [Laboratoire de l' Accélérateur Linéaire, Université de Paris-Sud, CNRS/IN2P3, Bâtiment 200, BP 34, 91898 Orsay Cedex (France); Martins, C.J.A.P.; Monteiro, A.M.R.V.L., E-mail: A.Avgoustidis@damtp.cam.ac.uk, E-mail: gluzzi@lal.in2p3.fr, E-mail: Carlos.Martins@astro.up.pt, E-mail: up090322024@alunos.fc.up.pt [Centro de Astrofísica, Universidade do Porto, Rua das Estrelas, 4150-762 Porto (Portugal)

2012-02-01

The relation between redshift and the CMB temperature, T{sub CMB}(z) = T{sub 0}(1+z) is a key prediction of standard cosmology, but is violated in many non-standard models. Constraining possible deviations to this law is an effective way to test the ΛCDM paradigm and search for hints of new physics. We present state-of-the-art constraints, using both direct and indirect measurements. In particular, we point out that in models where photons can be created or destroyed, not only does the temperature-redshift relation change, but so does the distance duality relation, and these departures from the standard behaviour are related, providing us with an opportunity to improve constraints. We show that current datasets limit possible deviations of the form T{sub CMB}(z) = T{sub 0}(1+z){sup 1−β} to be β = 0.004±0.016 up to a redshift z ∼ 3. We also discuss how, with the next generation of space and ground-based experiments, these constraints can be improved by more than one order of magnitude.

Constraints on the CMB temperature-redshift dependence from SZ and distance measurements

International Nuclear Information System (INIS)

Avgoustidis, A.; Luzzi, G.; Martins, C.J.A.P.; Monteiro, A.M.R.V.L.

2012-01-01

The relation between redshift and the CMB temperature, T CMB (z) = T 0 (1+z) is a key prediction of standard cosmology, but is violated in many non-standard models. Constraining possible deviations to this law is an effective way to test the ΛCDM paradigm and search for hints of new physics. We present state-of-the-art constraints, using both direct and indirect measurements. In particular, we point out that in models where photons can be created or destroyed, not only does the temperature-redshift relation change, but so does the distance duality relation, and these departures from the standard behaviour are related, providing us with an opportunity to improve constraints. We show that current datasets limit possible deviations of the form T CMB (z) = T 0 (1+z) 1−β to be β = 0.004±0.016 up to a redshift z ∼ 3. We also discuss how, with the next generation of space and ground-based experiments, these constraints can be improved by more than one order of magnitude

Planck 2013 results. XV. CMB power spectra and likelihood

DEFF Research Database (Denmark)

Tauber, Jan; Bartlett, J.G.; Bucher, M.

2014-01-01

This paper presents the Planck 2013 likelihood, a complete statistical description of the two-point correlation function of the CMB temperature fluctuations that accounts for all known relevant uncertainties, both instrumental and astrophysical in nature. We use this likelihood to derive our best...

Does the small CMB quadrupole moment suggest new physics?

CERN Document Server

Cline, J M; Lesgourgues, Julien; Cline, James M.; Crotty, Patrick; Lesgourgues, Julien

2003-01-01

Motivated by WMAP's confirmation of an anomalously low value of the quadrupole moment of the CMB temperature fluctuations, we investigate the effects on the CMB of cutting off the primordial power spectrum P(k) at low wave numbers. This could arise, for example, from a break in the inflaton potential, a prior period of matter or radiation domination, or an oscillating scalar field which couples to the inflaton. We reanalyze the full WMAP parameter space supplemented by a low-k cutoff for P(k). The temperature correlations by themselves are better fit by a cutoff spectrum, but including the TE temperature-polarization spectrum reduces this preference to a 1.4 sigma effect. Inclusion of large scale structure data does not change the conclusion. If taken seriously, the low-k cutoff is correlated with optical depth so that reionization occurs even earlier than indicated by the WMAP analysis.

Detecting relic gravitational waves in the CMB: The contamination caused by the cosmological birefringence

Directory of Open Access Journals (Sweden)

Wen Zhao

2014-10-01

Full Text Available The B-mode polarization of the cosmic microwave background (CMB radiation is an excellent information channel for the detection of relic gravitational waves. However, the detection is contaminated by the B-mode polarization generated by some other effects. In this paper, we discuss the contaminations caused by the cosmological birefringence, which converts the CMB E-mode to the B-mode, and forms the effective noise for the detection of gravitational waves. We find that this contamination is significant, if the rotation angle is large. However, this kind of B-mode can be properly de-rotated, and the effective noises can be greatly reduced. We find that, comparing with the contaminations caused by cosmic weak lensing, the residual polarization generated by the cosmological birefringence is negligible for the detection of relic gravitational waves in the CMB.

CMB anisotropies at all orders: the non-linear Sachs-Wolfe formula

International Nuclear Information System (INIS)

Roldan, Omar

2017-01-01

We obtain the non-linear generalization of the Sachs-Wolfe + integrated Sachs-Wolfe (ISW) formula describing the CMB temperature anisotropies. Our formula is valid at all orders in perturbation theory, is also valid in all gauges and includes scalar, vector and tensor modes. A direct consequence of our results is that the maps of the logarithmic temperature anisotropies are much cleaner than the usual CMB maps, because they automatically remove many secondary anisotropies. This can for instance, facilitate the search for primordial non-Gaussianity in future works. It also disentangles the non-linear ISW from other effects. Finally, we provide a method which can iteratively be used to obtain the lensing solution at the desired order.

CMB anisotropies at all orders: the non-linear Sachs-Wolfe formula

Energy Technology Data Exchange (ETDEWEB)

Roldan, Omar, E-mail: oaroldan@if.ufrj.br [Instituto de Física, Universidade Federal do Rio de Janeiro, 21941-972, Rio de Janeiro, RJ (Brazil)

2017-08-01

We obtain the non-linear generalization of the Sachs-Wolfe + integrated Sachs-Wolfe (ISW) formula describing the CMB temperature anisotropies. Our formula is valid at all orders in perturbation theory, is also valid in all gauges and includes scalar, vector and tensor modes. A direct consequence of our results is that the maps of the logarithmic temperature anisotropies are much cleaner than the usual CMB maps, because they automatically remove many secondary anisotropies. This can for instance, facilitate the search for primordial non-Gaussianity in future works. It also disentangles the non-linear ISW from other effects. Finally, we provide a method which can iteratively be used to obtain the lensing solution at the desired order.

Cosmological parameters from CMB and other data: A Monte Carlo approach

International Nuclear Information System (INIS)

Lewis, Antony; Bridle, Sarah

2002-01-01

We present a fast Markov chain Monte Carlo exploration of cosmological parameter space. We perform a joint analysis of results from recent cosmic microwave background (CMB) experiments and provide parameter constraints, including σ 8 , from the CMB independent of other data. We next combine data from the CMB, HST Key Project, 2dF galaxy redshift survey, supernovae type Ia and big-bang nucleosynthesis. The Monte Carlo method allows the rapid investigation of a large number of parameters, and we present results from 6 and 9 parameter analyses of flat models, and an 11 parameter analysis of non-flat models. Our results include constraints on the neutrino mass (m ν < or approx. 3 eV), equation of state of the dark energy, and the tensor amplitude, as well as demonstrating the effect of additional parameters on the base parameter constraints. In a series of appendixes we describe the many uses of importance sampling, including computing results from new data and accuracy correction of results generated from an approximate method. We also discuss the different ways of converting parameter samples to parameter constraints, the effect of the prior, assess the goodness of fit and consistency, and describe the use of analytic marginalization over normalization parameters

Inflation in the closed FLRW model and the CMB

Energy Technology Data Exchange (ETDEWEB)

Bonga, Béatrice; Gupt, Brajesh; Yokomizo, Nelson, E-mail: bpb165@psu.edu, E-mail: bgupt@gravity.psu.edu, E-mail: yokomizo@gravity.psu.edu [Institute for Gravitation and the Cosmos and Physics Department, The Pennsylvania State University, University Park, PA 16802 (United States)

2016-10-01

Recent cosmic microwave background (CMB) observations put strong constraints on the spatial curvature via estimation of the parameter Ω{sub k} assuming an almost scale invariant primordial power spectrum. We study the evolution of the background geometry and gauge-invariant scalar perturbations in an inflationary closed FLRW model and calculate the primordial power spectrum. We find that the inflationary dynamics is modified due to the presence of spatial curvature, leading to corrections to the nearly scale invariant power spectrum at the end of inflation. When evolved to the surface of last scattering, the resulting temperature anisotropy spectrum ( C {sup TT}{sub ℓ}) shows deficit of power at low multipoles (ℓ < 20). By comparing our results with the recent Planck data we discuss the role of spatial curvature in accounting for CMB anomalies and in the estimation of the parameter Ω{sub k}. Since the curvature effects are limited to low multipoles, the Planck estimation of cosmological parameters remains robust under inclusion of positive spatial curvature.

Planck 2015 results. IX. Diffuse component separation: CMB maps

CERN Document Server

Adam, R.; Aghanim, N.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartlett, J.G.; Bartolo, N.; Basak, S.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Casaponsa, B.; Castex, G.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.R.; Chiang, H.C.; Christensen, P.R.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Desert, F.X.; Dickinson, C.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Falgarone, E.; Fantaye, Y.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Ghosh, T.; Giard, M.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kisner, T.S.; Kneissl, R.; Knoche, J.; Krachmalnicoff, N.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Le Jeune, M.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Mazzotta, P.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mitra, S.; Miville-Deschenes, M.A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Racine, B.; Reach, W.T.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Roudier, G.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Spencer, L.D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-01-01

We present foreground-reduced CMB maps derived from the full Planck data set in both temperature and polarization. Compared to the corresponding Planck 2013 temperature sky maps, the total data volume is larger by a factor of 3.2 for frequencies between 30 and 70 GHz, and by 1.9 for frequencies between 100 and 857 GHz. In addition, systematic errors in the forms of temperature-to-polarization leakage, analogue-to-digital conversion uncertainties, and very long time constant errors have been dramatically reduced, to the extent that the cosmological polarization signal may now be robustly recovered on angular scales $\\ell\\gtrsim40$. On the very largest scales, instrumental systematic residuals are still non-negligible compared to the expected cosmological signal, and modes with $\\ell < 20$ are accordingly suppressed in the current polarization maps by high-pass filtering. As in 2013, four different CMB component separation algorithms are applied to these observations, providing a measure of stability with re...

Determination of neutrino mass hierarchy by 21 cm line and CMB B-mode polarization observations

Energy Technology Data Exchange (ETDEWEB)

Oyama, Yoshihiko, E-mail: oyamayo@post.kek.jp [The Graduate University for Advanced Studies (SOKENDAI), 1-1 Oho, Tsukuba 305-0801 (Japan); Shimizu, Akie [The Graduate University for Advanced Studies (SOKENDAI), 1-1 Oho, Tsukuba 305-0801 (Japan); Kohri, Kazunori [The Graduate University for Advanced Studies (SOKENDAI), 1-1 Oho, Tsukuba 305-0801 (Japan); Institute of Particle and Nuclear Studies, KEK, 1-1 Oho, Tsukuba 305-0801 (Japan)

2013-01-29

We focus on the ongoing and future observations for both the 21 cm line and the CMB B-mode polarization produced by a CMB lensing, and study their sensitivities to the effective number of neutrino species, the total neutrino mass, and the neutrino mass hierarchy. We find that combining the CMB observations with future square kilometer arrays optimized for 21 cm line such as Omniscope can determine the neutrino mass hierarchy at 2{sigma}. We also show that a more feasible combination of Planck + POLARBEAR and SKA can strongly improve errors of the bounds on the total neutrino mass and the effective number of neutrino species to be {Delta}{Sigma}m{sub {nu}}{approx}0.12 eV and {Delta}N{sub {nu}}{approx}0.38 at 2{sigma}, respectively.

Punctuated inflation and the low CMB multipoles

International Nuclear Information System (INIS)

Jain, Rajeev Kumar; Sriramkumar, L.; Chingangbam, Pravabati; Gong, Jinn-Ouk; Souradeep, Tarun

2009-01-01

We investigate inflationary scenarios driven by a class of potentials which are similar in form to those that arise in certain minimal supersymmetric extensions of the standard model. We find that these potentials allow a brief period of departure from inflation sandwiched between two stages of slow roll inflation. We show that such a background behavior leads to a step like feature in the scalar power spectrum. We set the scales such that the drop in the power spectrum occurs at a length scale that corresponds to the Hubble radius today — a feature that seems necessary to explain the lower power observed in the quadrupole moment of the Cosmic Microwave Background (CMB) anisotropies. We perform a Markov Chain Monte Carlo analysis to determine the values of the model parameters that provide the best fit to the recent WMAP 5-year data for the CMB angular power spectrum. We find that an inflationary spectrum with a suppression of power at large scales that we obtain leads to a much better fit (with just one extra parameter, χ eff 2 improves by 6.62) of the observed data when compared to the best fit reference ΛCDM model with a featureless, power law, primordial spectrum

CMB anisotropies from patchy reionisation and diffuse Sunyaev-Zel'dovich effects

Energy Technology Data Exchange (ETDEWEB)

Fidler, Christian; Ringeval, Christophe, E-mail: christophe.ringeval@uclouvain.be, E-mail: christian.fidler@uclouvain.be [Centre for Cosmology, Particle Physics and Phenomenology, Institute of Mathematics and Physics, Louvain University, 2 Chemin du Cyclotron, 1348 Louvain-la-Neuve (Belgium)

2017-10-01

Anisotropies in the Cosmic Microwave Background (CMB) can be induced during the later stages of cosmic evolution, and in particular during and after the Epoch of Reionisation. Inhomogeneities in the ionised fraction, but also in the baryon density, in the velocity fields and in the gravitational potentials are expected to generate correlated CMB perturbations. We present a complete relativistic treatment of all these effects, up to second order in perturbation theory, that we solve using the numerical Boltzmann code (\\SONG). The physical origin and relevance of all second order terms are carefully discussed. In addition to collisional and gravitational contributions, we identify the diffuse analogue of the blurring and kinetic Sunyaev-Zel'dovich (SZ) effects. Our approach naturally includes the correlations between the imprint from patchy reionisation and the diffuse SZ effects thereby allowing us to derive reliable estimates of the induced temperature and polarisation CMB angular power spectra. In particular, we show that the B -modes generated at intermediate length-scales (ℓ ≅ 100) have the same amplitude as the B -modes coming from primordial gravitational waves with a tensor-to-scalar ratio r =10{sup −4}.

A constraint on Planck-scale modifications to electrodynamics with CMB polarization data

International Nuclear Information System (INIS)

Gubitosi, Giulia; Pagano, Luca; Amelino-Camelia, Giovanni; Melchiorri, Alessandro; Cooray, Asantha

2009-01-01

We show that the Cosmic Microwave Background (CMB) polarization data gathered by the BOOMERanG 2003 flight and WMAP provide an opportunity to investigate in-vacuo birefringence, of a type expected in some quantum pictures of space-time, with a sensitivity that extends even beyond the desired Planck-scale energy. In order to render this constraint more transparent we rely on a well studied phenomenological model of quantum-gravity-induced birefringence, in which one easily establishes that effects introduced at the Planck scale would amount to values of a dimensionless parameter, denoted by ξ, with respect to the Planck energy which are roughly of order 1. By combining BOOMERanG and WMAP data we estimate ξ ≅ −0.110±0.075 at the 68% c.l. Moreover, we forecast on the sensitivity to ξ achievable by future CMB polarization experiments (PLANCK, Spider, EPIC), which, in the absence of systematics, will be at the 1-σ confidence of 8.5 × 10 −4 (PLANCK), 6.1 × 10 −3 (Spider), and 1.0 × 10 −5 (EPIC) respectively. The cosmic variance-limited sensitivity from CMB is 6.1 × 10 −6

Extraction Of Cobalt From Spent CMB Catalyst Using Supercritical CO2

Directory of Open Access Journals (Sweden)

Joo S.-H.

2015-06-01

Full Text Available The metal extraction from spent CMB catalyst using supercritical CO2(scCO2 was investigated with single organic system, binary organic system and ternary organic system to extract metal ions. Leaching solution of spent CMB catalyst containing 389 mg L−1 Co2+, 187 mg L−1 Mn2+, 133 mg L−1 Na+, 14.97 mg L−1 Ca2+ and 13.2 mg L−1 Mg2+. The method consists of scCO2/ligands complexation process and metal extraction process at 60°C and 200bar. The result showed the Co and Mn was selectively extracted from Mg, Ca and Na in the ternary system of mixture of Cyanex272, DEA and Alamine304-I.

A note on the birefringence angle estimation in CMB data analysis

Energy Technology Data Exchange (ETDEWEB)

Gruppuso, A. [INAF, Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, via P. Gobetti 101, I-40129 Bologna (Italy); Maggio, G. [INAF, Osservatorio Astronomico di Trieste, Via G.B. Tiepolo 11, Trieste (Italy); Molinari, D.; Natoli, P., E-mail: gruppuso@iasbo.inaf.it, E-mail: maggio@oats.inaf.it, E-mail: molinari@iasfbo.inaf.it, E-mail: ntlpla@unife.it [Dipartimento di Fisica e Scienze della Terra and INFN, Università degli Studi di Ferrara, Via Saragat 1, I-44100 Ferrara (Italy)

2016-05-01

Parity violating physics beyond the standard model of particle physics induces a rotation of the linear polarization of photons. This effect, also known as cosmological birefringence (CB), can be tested with the observations of the cosmic microwave background (CMB) anisotropies which are linearly polarized at the level of 5–10%. In particular CB produces non-null CMB cross correlations between temperature and B mode-polarization, and between E- and B-mode polarization. Here we study the properties of the so called D-estimators, often used to constrain such an effect. After deriving the framework of both frequentist and Bayesian analysis, we discuss the interplay between birefringence and weak-lensing, which, albeit parity conserving, modifies pre-existing TB and EB cross correlation.

The Classification of Universes

Energy Technology Data Exchange (ETDEWEB)

Bjorken, J

2004-04-09

We define a universe as the contents of a spacetime box with comoving walls, large enough to contain essentially all phenomena that can be conceivably measured. The initial time is taken as the epoch when the lowest CMB modes undergo horizon crossing, and the final time taken when the wavelengths of CMB photons are comparable with the Hubble scale, i.e. with the nominal size of the universe. This allows the definition of a local ensemble of similarly constructed universes, using only modest extrapolations of the observed behavior of the cosmos. We then assume that further out in spacetime, similar universes can be constructed but containing different standard model parameters. Within this multiverse ensemble, it is assumed that the standard model parameters are strongly correlated with size, i.e. with the value of the inverse Hubble parameter at the final time, in a manner as previously suggested. This allows an estimate of the range of sizes which allow life as we know it, and invites a speculation regarding the most natural distribution of sizes. If small sizes are favored, this in turn allows some understanding of the hierarchy problems of particle physics. Subsequent sections of the paper explore other possible implications. In all cases, the approach is as bottoms up and as phenomenological as possible, and suggests that theories of the multiverse so constructed may in fact lay some claim of being scientific.

The Classification of Universes

International Nuclear Information System (INIS)

Bjorken, J

2004-01-01

We define a universe as the contents of a spacetime box with comoving walls, large enough to contain essentially all phenomena that can be conceivably measured. The initial time is taken as the epoch when the lowest CMB modes undergo horizon crossing, and the final time taken when the wavelengths of CMB photons are comparable with the Hubble scale, i.e. with the nominal size of the universe. This allows the definition of a local ensemble of similarly constructed universes, using only modest extrapolations of the observed behavior of the cosmos. We then assume that further out in spacetime, similar universes can be constructed but containing different standard model parameters. Within this multiverse ensemble, it is assumed that the standard model parameters are strongly correlated with size, i.e. with the value of the inverse Hubble parameter at the final time, in a manner as previously suggested. This allows an estimate of the range of sizes which allow life as we know it, and invites a speculation regarding the most natural distribution of sizes. If small sizes are favored, this in turn allows some understanding of the hierarchy problems of particle physics. Subsequent sections of the paper explore other possible implications. In all cases, the approach is as bottoms up and as phenomenological as possible, and suggests that theories of the multiverse so constructed may in fact lay some claim of being scientific

Analysing the Effect on CMB in a Parity and Charge Parity Violating Varying Alpha Theory

Energy Technology Data Exchange (ETDEWEB)

Maity, Debaprasad; /NCTS, Taipei /Taiwan, Natl. Taiwan U.; Chen, Pisin; /NCTS, Taipei /Taiwan, Natl. Taiwan U. /KIPAC, Menlo Park /SLAC

2012-09-14

In this paper we study in detail the effect of our recently proposed model of parity and charge-parity (PCP) violating varying alpha on the Cosmic Microwave Background (CMB) photon passing through the intra galaxy-cluster medium (ICM). The ICM is well known to be composed of magnetized plasma. According to our model, the polarization and intensity of the CMB would be affected when traversing through the ICM due to non-trivial scalar photon interactions. We have calculated the evolution of such polarization and intensity collectively, known as the stokes parameters of the CMB photon during its journey through the ICM and tested our results against the Sunyaev-Zel'dovich (SZ) measurement on Coma galaxy cluster. Our model contains a PCP violating parameter, {beta}, and a scale of alpha variation {omega}. Using the derived constrained on the photon-to-scalar conversion probability, {bar P}{sub {gamma}{yields}{phi}}, for Coma cluster in ref.[34] we found a contour plot in the ({omega},{beta}) parameter plane. The {beta} = 0 line in this parameter space corresponds to well-studied Maxwell-dilaton type models which has lower bound on {omega} {approx}> 6.4 x 10{sup 9} GeV. In general, as the absolute value of {beta} increases, lower bound on {omega} also increases. Our model in general predicts the modification of the CMB polarization with a non-trivial dependence on the parity violating coupling parameter {beta}. However, it is unconstrained in this particular study. We show that this effect can in principle be detected in the future measurements on CMB polarization such that {beta} can also be constrained.

Impact of calibration errors on CMB component separation using FastICA and ILC

Science.gov (United States)

Dick, Jason; Remazeilles, Mathieu; Delabrouille, Jacques

2010-01-01

The separation of emissions from different astrophysical processes is an important step towards the understanding of observational data. This topic of component separation is of particular importance in the observation of the relic cosmic microwave background (CMB) radiation, as performed by the Wilkinson Microwave Anisotropy Probe satellite and the more recent Planck mission, launched on 2009 May 14 from Kourou and currently taking data. When performing any sort of component separation, some assumptions about the components must be used. One assumption that many techniques typically use is knowledge of the frequency scaling of one or more components. This assumption may be broken in the presence of calibration errors. Here we compare, in the context of imperfect calibration, the recovery of a clean map of emission of the CMB from observational data with two methods: FastICA (which makes no assumption of the frequency scaling of the components) and an `Internal Linear Combination' (ILC), which explicitly extracts a component with a given frequency scaling. We find that even in the presence of small calibration errors (less than 1 per cent) with a Planck-style mission, the ILC method can lead to inaccurate CMB reconstruction in the high signal-to-noise ratio regime, because of partial cancellation of the CMB emission in the recovered map. While there is no indication that the failure of the ILC will translate to other foreground cleaning or component separation techniques, we propose that all methods which assume knowledge of the frequency scaling of one or more components be careful to estimate the effects of calibration errors.

MODELING ATMOSPHERIC EMISSION FOR CMB GROUND-BASED OBSERVATIONS

Energy Technology Data Exchange (ETDEWEB)

Errard, J.; Borrill, J. [Space Sciences Laboratory, University of California, Berkeley, CA 94720 (United States); Ade, P. A. R. [School of Physics and Astronomy, Cardiff University, Cardiff CF10 3XQ (United Kingdom); Akiba, Y.; Chinone, Y. [High Energy Accelerator Research Organization (KEK), Tsukuba, Ibaraki 305-0801 (Japan); Arnold, K.; Atlas, M.; Barron, D.; Elleflot, T. [Department of Physics, University of California, San Diego, CA 92093-0424 (United States); Baccigalupi, C.; Fabbian, G. [International School for Advanced Studies (SISSA), Trieste I-34014 (Italy); Boettger, D. [Department of Astronomy, Pontifica Universidad Catolica de Chile (Chile); Chapman, S. [Department of Physics and Atmospheric Science, Dalhousie University, Halifax, NS, B3H 4R2 (Canada); Cukierman, A. [Department of Physics, University of California, Berkeley, CA 94720 (United States); Delabrouille, J. [AstroParticule et Cosmologie, Univ Paris Diderot, CNRS/IN2P3, CEA/Irfu, Obs de Paris, Sorbonne Paris Cité (France); Dobbs, M.; Gilbert, A. [Physics Department, McGill University, Montreal, QC H3A 0G4 (Canada); Ducout, A.; Feeney, S. [Department of Physics, Imperial College London, London SW7 2AZ (United Kingdom); Feng, C. [Department of Physics and Astronomy, University of California, Irvine (United States); and others

2015-08-10

Atmosphere is one of the most important noise sources for ground-based cosmic microwave background (CMB) experiments. By increasing optical loading on the detectors, it amplifies their effective noise, while its fluctuations introduce spatial and temporal correlations between detected signals. We present a physically motivated 3D-model of the atmosphere total intensity emission in the millimeter and sub-millimeter wavelengths. We derive a new analytical estimate for the correlation between detectors time-ordered data as a function of the instrument and survey design, as well as several atmospheric parameters such as wind, relative humidity, temperature and turbulence characteristics. Using an original numerical computation, we examine the effect of each physical parameter on the correlations in the time series of a given experiment. We then use a parametric-likelihood approach to validate the modeling and estimate atmosphere parameters from the polarbear-i project first season data set. We derive a new 1.0% upper limit on the linear polarization fraction of atmospheric emission. We also compare our results to previous studies and weather station measurements. The proposed model can be used for realistic simulations of future ground-based CMB observations.

Large scale CMB anomalies from thawing cosmic strings

Energy Technology Data Exchange (ETDEWEB)

Ringeval, Christophe [Centre for Cosmology, Particle Physics and Phenomenology, Institute of Mathematics and Physics, Louvain University, 2 Chemin du Cyclotron, 1348 Louvain-la-Neuve (Belgium); Yamauchi, Daisuke; Yokoyama, Jun' ichi [Research Center for the Early Universe (RESCEU), Graduate School of Science, The University of Tokyo, Tokyo 113-0033 (Japan); Bouchet, François R., E-mail: christophe.ringeval@uclouvain.be, E-mail: yamauchi@resceu.s.u-tokyo.ac.jp, E-mail: yokoyama@resceu.s.u-tokyo.ac.jp, E-mail: bouchet@iap.fr [Institut d' Astrophysique de Paris, UMR 7095-CNRS, Université Pierre et Marie Curie, 98bis boulevard Arago, 75014 Paris (France)

2016-02-01

Cosmic strings formed during inflation are expected to be either diluted over super-Hubble distances, i.e., invisible today, or to have crossed our past light cone very recently. We discuss the latter situation in which a few strings imprint their signature in the Cosmic Microwave Background (CMB) Anisotropies after recombination. Being almost frozen in the Hubble flow, these strings are quasi static and evade almost all of the previously derived constraints on their tension while being able to source large scale anisotropies in the CMB sky. Using a local variance estimator on thousand of numerically simulated Nambu-Goto all sky maps, we compute the expected signal and show that it can mimic a dipole modulation at large angular scales while being negligible at small angles. Interestingly, such a scenario generically produces one cold spot from the thawing of a cosmic string loop. Mixed with anisotropies of inflationary origin, we find that a few strings of tension GU = O(1) × 10{sup −6} match the amplitude of the dipole modulation reported in the Planck satellite measurements and could be at the origin of other large scale anomalies.

Planck 2013 results. XXIII. Isotropy and Statistics of the CMB

DEFF Research Database (Denmark)

Planck Collaboration,; Ade, P. A. R.; Aghanim, N.

2013-01-01

The two fundamental assumptions of the standard cosmological model - that the initial fluctuations are statistically isotropic and Gaussian - are rigorously tested using maps of the CMB anisotropy from the \\Planck\\ satellite. The detailed results are based on studies of four independent estimates...

The Atacama Cosmology Telescope: Likelihood for Small-Scale CMB Data

Science.gov (United States)

Dunkley, J.; Calabrese, E.; Sievers, J.; Addison, G. E.; Battaglia, N.; Battistelli, E. S.; Bond, J. R.; Das, S.; Devlin, M. J.; Dunner, R.;

Multiscale analysis of the CMB temperature derivatives

Energy Technology Data Exchange (ETDEWEB)

Marcos-Caballero, A.; Martínez-González, E.; Vielva, P., E-mail: marcos@ifca.unican.es, E-mail: martinez@ifca.unican.es, E-mail: vielva@ifca.unican.es [Instituto de Física de Cantabria, CSIC-Universidad de Cantabria, Avda. de los Castros s/n, 39005 Santander, Spain. (Spain)

2017-02-01

We study the Planck CMB temperature at different scales through its derivatives up to second order, which allows one to characterize the local shape and isotropy of the field. The problem of having an incomplete sky in the calculation and statistical characterization of the derivatives is addressed in the paper. The analysis confirms the existence of a low variance in the CMB at large scales, which is also noticeable in the derivatives. Moreover, deviations from the standard model in the gradient, curvature and the eccentricity tensor are studied in terms of extreme values on the data. As it is expected, the Cold Spot is detected as one of the most prominent peaks in terms of curvature, but additionally, when the information of the temperature and its Laplacian are combined, another feature with similar probability at the scale of 10{sup o} is also observed. However, the p -value of these two deviations increase above the 6% when they are referred to the variance calculated from the theoretical fiducial model, indicating that these deviations can be associated to the low variance anomaly. Finally, an estimator of the directional anisotropy for spinorial quantities is introduced, which is applied to the spinors derived from the field derivatives. An anisotropic direction whose probability is <1% is detected in the eccentricity tensor.

Probing CPT violation with CMB polarization measurements

Energy Technology Data Exchange (ETDEWEB)

Xia Junqing, E-mail: xia@sissa.i [Scuola Internazionale Superiore di Studi Avanzati, Via Beirut 2-4, I-34014 Trieste (Italy); Li Hong; Zhang Xinmin [Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-4, Beijing 100049 (China); Theoretical Physics Center for Science Facilities (TPCSF), Chinese Academy of Science (China)

2010-04-12

The electrodynamics modified by the Chern-Simons term L{sub cs}approxp{sub m}uA{sub n}uF-tilde{sup m}u{sup n}u with a non-vanishing p{sub m}u violates the Charge-Parity-Time Reversal symmetry (CPT) and rotates the linear polarizations of the propagating Cosmic Microwave Background (CMB) photons. In this Letter we measure the rotation angle DELTAalpha by performing a global analysis on the current CMB polarization measurements from the five-year Wilkinson Microwave Anisotropy Probe (WMAP5), BOOMERanG 2003 (B03), BICEP and QUaD using a Markov Chain Monte Carlo method. Neglecting the systematic errors of these experiments, we find that the results from WMAP5, B03 and BICEP all are consistent and their combination gives DELTAalpha=-2.62+-0.87deg (68% C.L.), indicating a 3sigma detection of the CPT violation. The QUaD data alone gives DELTAalpha=0.59+-0.42deg (68% C.L.) which has an opposite sign for the central value and smaller error bar compared to that obtained from WMAP5, B03 and BICEP. When combining all the polarization data together, we find DELTAalpha=0.09+-0.36deg (68% C.L.) which significantly improves the previous constraint on DELTAalpha and test the validity of the fundamental CPT symmetry at a higher level.

Using the CMB angular power spectrum to study Dark Matter-photon interactions

International Nuclear Information System (INIS)

Wilkinson, Ryan J.; Boehm, Céline; Lesgourgues, Julien

2014-01-01

In this paper, we explore the impact of Dark Matter-photon interactions on the CMB angular power spectrum. Using the one-year data release of the Planck satellite, we derive an upper bound on the Dark Matter-photon elastic scattering cross section of σ DM−γ ≤ 8 × 10 −31 (m DM /GeV) cm 2 (68% CL) if the cross section is constant and a present-day value of σ DM−γ ≤ 6 × 10 −40 (m DM /GeV) cm 2 (68% CL) if it scales as the temperature squared. For such a limiting cross section, both the B-modes and the TT angular power spectrum are suppressed with respect to ΛCDM predictions for ℓ∼>500 and ℓ∼>3000 respectively, indicating that forthcoming data from CMB polarisation experiments and Planck could help to constrain and characterise the physics of the dark sector. This essentially initiates a new type of dark matter search that is independent of whether dark matter is annihilating, decaying or asymmetric. Thus, any CMB experiment with the ability to measure the temperature and/or polarisation power spectra at high ℓ should be able to investigate the potential interactions of dark matter and contribute to our fundamental understanding of its nature

A constraint on Planck-scale modifications to electrodynamics with CMB polarization data

Energy Technology Data Exchange (ETDEWEB)

Gubitosi, Giulia; Pagano, Luca; Amelino-Camelia, Giovanni; Melchiorri, Alessandro [Physics Department, University of Rome ' ' La Sapienza' ' and Sezione Roma1 INFN, P.le Aldo Moro 2, 00185 Rome (Italy); Cooray, Asantha, E-mail: giulia.gubitosi@roma1.infn.it, E-mail: luca.pagano@roma1.infn.it, E-mail: giovanni.amelino-camelia@roma1.infn.it, E-mail: alessandro.melchiorri@roma1.infn.it, E-mail: acooray@uci.edu [Center for Cosmology, Dept. of Physics and Astronomy, University of California Irvine, Irvine, CA 92697 (United States)

2009-08-01

We show that the Cosmic Microwave Background (CMB) polarization data gathered by the BOOMERanG 2003 flight and WMAP provide an opportunity to investigate in-vacuo birefringence, of a type expected in some quantum pictures of space-time, with a sensitivity that extends even beyond the desired Planck-scale energy. In order to render this constraint more transparent we rely on a well studied phenomenological model of quantum-gravity-induced birefringence, in which one easily establishes that effects introduced at the Planck scale would amount to values of a dimensionless parameter, denoted by ξ, with respect to the Planck energy which are roughly of order 1. By combining BOOMERanG and WMAP data we estimate ξ ≅ −0.110±0.075 at the 68% c.l. Moreover, we forecast on the sensitivity to ξ achievable by future CMB polarization experiments (PLANCK, Spider, EPIC), which, in the absence of systematics, will be at the 1-σ confidence of 8.5 × 10{sup −4} (PLANCK), 6.1 × 10{sup −3} (Spider), and 1.0 × 10{sup −5} (EPIC) respectively. The cosmic variance-limited sensitivity from CMB is 6.1 × 10{sup −6}.

Working Group Report: Dark Energy and CMB

Energy Technology Data Exchange (ETDEWEB)

Dodelson, S.; Honscheid, K.; Abazajian, K.; Carlstrom, J.; Huterer, D.; Jain, B.; Kim, A.; Kirkby, D.; Lee, A.; Padmanabhan, N.; Rhodes, J.; Weinberg, D.

2013-09-20

The American Physical Society's Division of Particles and Fields initiated a long-term planning exercise over 2012-13, with the goal of developing the community's long term aspirations. The sub-group "Dark Energy and CMB" prepared a series of papers explaining and highlighting the physics that will be studied with large galaxy surveys and cosmic microwave background experiments. This paper summarizes the findings of the other papers, all of which have been submitted jointly to the arXiv.

Halo Pressure Profile through the Skew Cross-power Spectrum of the Sunyaev–Zel’dovich Effect and CMB Lensing in Planck

Energy Technology Data Exchange (ETDEWEB)

Timmons, Nicholas; Cooray, Asantha; Feng, Chang [Department of Physics and Astronomy, University of California, Irvine, CA 92697 (United States); Keating, Brian [Department of Physics, University of California, San Diego, La Jolla, CA 92093 (United States)

2017-11-01

We measure the cosmic microwave background (CMB) skewness power spectrum in Planck , using frequency maps of the HFI instrument and the Sunyaev–Zel’dovich (SZ) component map. The two-to-one skewness power spectrum measures the cross-correlation between CMB lensing and the thermal SZ effect. We also directly measure the same cross-correlation using the Planck CMB lensing map and the SZ map and compare it to the cross-correlation derived from the skewness power spectrum. We model fit the SZ power spectrum and CMB lensing–SZ cross-power spectrum via the skewness power spectrum to constrain the gas pressure profile of dark matter halos. The gas pressure profile is compared to existing measurements in the literature including a direct estimate based on the stacking of SZ clusters in Planck .

When can preheating affect the CMB?

Science.gov (United States)

Tsujikawa, Shinji; Bassett, Bruce A.

2002-05-01

We discuss the principles governing the selection of inflationary models for which preheating can affect the CMB. This is a (fairly small) subset of those models which have nonnegligible entropy/isocurvature perturbations on large scales during inflation. We study new models which belong to this class-two-field inflation with negative nonminimal coupling and hybrid/double/supernatural inflation models where the tachyonic growth of entropy perturbations can lead to the variation of the curvature perturbation, /R, on super-Hubble scales. Finally, we present evidence against recent claims for the variation of /R in the absence of substantial super-Hubble entropy perturbations.

Imitating intrinsic alignments: a bias to the CMB lensing-galaxy shape cross-correlation power spectrum induced by the large-scale structure bispectrum

Science.gov (United States)

Merkel, Philipp M.; Schäfer, Björn Malte

2017-10-01

Cross-correlating the lensing signals of galaxies and comic microwave background (CMB) fluctuations is expected to provide valuable cosmological information. In particular, it may help tighten constraints on parameters describing the properties of intrinsically aligned galaxies at high redshift. To access the information conveyed by the cross-correlation signal, its accurate theoretical description is required. We compute the bias to CMB lensing-galaxy shape cross-correlation measurements induced by non-linear structure growth. Using tree-level perturbation theory for the large-scale structure bispectrum, we find that the bias is negative on most angular scales, therefore mimicking the signal of intrinsic alignments. Combining Euclid-like galaxy lensing data with a CMB experiment comparable to the Planck satellite mission, the bias becomes significant only on smallest scales (ℓ ≳ 2500). For improved CMB observations, however, the corrections amount to 10-15 per cent of the CMB lensing-intrinsic alignment signal over a wide multipole range (10 ≲ ℓ ≲ 2000). Accordingly, the power spectrum bias, if uncorrected, translates into 2σ and 3σ errors in the determination of the intrinsic alignment amplitude in the case of CMB stage III and stage IV experiments, respectively.

Constraining resonant photon-axion conversions in the Early Universe

International Nuclear Information System (INIS)

Mirizzi, Alessandro; Redondo, Javier; Sigl, Guenter

2009-05-01

The presence of a primordial magnetic field would have induced resonant conversions between photons and axion-like particles (ALPs) during the thermal history of the Universe. These conversions would have distorted the blackbody spectrum of the cosmic microwave background (CMB). In this context, we derive bounds on the photon-ALP resonant conversions using the high precision CMB spectral data collected by the FIRAS instrument on board of the Cosmic Background Explorer. We obtain upper limits on the product of the photon-ALP coupling constant g times the magnetic field strength B down to gB -13 GeV -1 nG for ALP masses below the eV scale. (orig.)

Planck 2015 results. XVI. Isotropy and statistics of the CMB

CERN Document Server

Ade, P.A.R.; Akrami, Y.; Aluri, P.K.; Arnaud, M.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartolo, N.; Basak, S.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Casaponsa, B.; Catalano, A.; Challinor, A.; Chamballu, A.; Chiang, H.C.; Christensen, P.R.; Church, S.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Combet, C.; Contreras, D.; Couchot, F.; Coulais, A.; Crill, B.P.; Cruz, M.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Desert, F.X.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Fantaye, Y.; Fergusson, J.; Fernandez-Cobos, R.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Frolov, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Ghosh, T.; Giard, M.; Giraud-Heraud, Y.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hansen, F.K.; Hanson, D.; Harrison, D.L.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huang, Z.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jaffe, T.R.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kim, J.; Kisner, T.S.; Knoche, J.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Liu, H.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marinucci, D.; Maris, M.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; McGehee, P.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mikkelsen, K.; Mitra, S.; Miville-Deschenes, M.A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J.A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Pant, N.; Paoletti, D.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Perrotta, F.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Popa, L.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rossetti, M.; Rotti, A.; Roudier, G.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Souradeep, T.; Spencer, L.D.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.; Zibin, J.P.; Zonca, A.

2016-01-01

We test the statistical isotropy and Gaussianity of the cosmic microwave background (CMB) anisotropies using observations made by the Planck satellite. Our results are based mainly on the full Planck mission for temperature, but also include some polarization measurements. In particular, we consider the CMB anisotropy maps derived from the multi-frequency Planck data by several component-separation methods. For the temperature anisotropies, we find excellent agreement between results based on these sky maps over both a very large fraction of the sky and a broad range of angular scales, establishing that potential foreground residuals do not affect our studies. Tests of skewness, kurtosis, multi-normality, N-point functions, and Minkowski functionals indicate consistency with Gaussianity, while a power deficit at large angular scales is manifested in several ways, for example low map variance. The results of a peak statistics analysis are consistent with the expectations of a Gaussian random field. The "Cold S...

Planck 2013 results. XXIII. Isotropy and Statistics of the CMB

CERN Document Server

Ade, P.A.R.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartlett, J.G.; Bartolo, N.; Battaner, E.; Battye, R.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R.C.; Cardoso, J.F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chary, R.R.; Chiang, L.Y.; Chiang, H.C.; Christensen, P.R.; Church, S.; Clements, D.L.; Colombi, S.; Colombo, L.P.L.; Couchot, F.; Coulais, A.; Crill, B.P.; Cruz, M.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.M.; Desert, F.X.; Diego, J.M.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Fantaye, Y.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Franceschi, E.; Frommert, M.; Galeotta, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Heraud, Y.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Hansen, M.; Hansen, F.K.; Hanson, D.; Harrison, D.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Hobson, M.; Holmes, W.A.; Hornstrup, A.; Hovest, W.; Huffenberger, K.M.; Jaffe, T.R.; Jaffe, A.H.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kim, J.; Kisner, T.S.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Laureijs, R.J.; Lawrence, C.R.; Leahy, J.P.; Leonardi, R.; Leroy, C.; Lesgourgues, J.; Liguori, M.; Lilje, P.B.; Linden-Vornle, M.; Lopez-Caniego, M.; Lubin, P.M.; Macias-Perez, J.F.; Maffei, B.; Maino, D.; Mandolesi, N.; Mangilli, A.; Marinucci, D.; Maris, M.; Marshall, D.J.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Matthai, F.; Mazzotta, P.; McEwen, J.D.; Meinhold, P.R.; Melchiorri, A.; Mendes, L.; Mennella, A.; Migliaccio, M.; Mikkelsen, K.; Mitra, S.; Miville-Deschenes, M.A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C.B.; Norgaard-Nielsen, H.U.; Noviello, F.; Novikov, D.; Novikov, I.; Osborne, S.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Pasian, F.; Patanchon, G.; Peiris, H.V.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Pogosyan, D.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G.W.; Prezeau, G.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Rath, C.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ricciardi, S.; Riller, T.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Rotti, A.; Roudier, G.; Rubino-Martin, J.A.; Rusholme, B.; Sandri, M.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M.D.; Shellard, E.P.S.; Souradeep, T.; Spencer, L.D.; Starck, J.L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sureau, F.; Sutter, P.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Turler, M.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; White, M.; Wilkinson, A.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-01-01

The two fundamental assumptions of the standard cosmological model - that the initial fluctuations are statistically isotropic and Gaussian - are rigorously tested using maps of the cosmic microwave background (CMB) anisotropy from the Planck satellite. Deviations from isotropy have been found and demonstrated to be robust against component separation algorithm, mask choice and frequency dependence. Many of these anomalies were previously observed in the WMAP data, and are now confirmed at similar levels of significance (about 3 sigma). However, we find little evidence for non-Gaussianity, with the exception of a few statistical signatures that seem to be associated with specific anomalies. In particular, we find that the quadrupole-octopole alignment is also connected to a low observed variance of the CMB signal. A power asymmetry is now found to persist to scales corresponding to about l=600, and can be described in the low-l regime by a phenomenological dipole modulation model. However, any primordial powe...

Testing non-minimally coupled inflation with CMB data: a Bayesian analysis

International Nuclear Information System (INIS)

Campista, Marcela; Benetti, Micol; Alcaniz, Jailson

2017-01-01

We use the most recent cosmic microwave background (CMB) data to perform a Bayesian statistical analysis and discuss the observational viability of inflationary models with a non-minimal coupling, ξ, between the inflaton field and the Ricci scalar. We particularize our analysis to two examples of small and large field inflationary models, namely, the Coleman-Weinberg and the chaotic quartic potentials. We find that ( i ) the ξ parameter is closely correlated with the primordial amplitude ; ( ii ) although improving the agreement with the CMB data in the r − n s plane, where r is the tensor-to-scalar ratio and n s the primordial spectral index, a non-null coupling is strongly disfavoured with respect to the minimally coupled standard ΛCDM model, since the upper bounds of the Bayes factor (odds) for ξ parameter are greater than 150:1.

Testing non-minimally coupled inflation with CMB data: a Bayesian analysis

Energy Technology Data Exchange (ETDEWEB)

Campista, Marcela; Benetti, Micol; Alcaniz, Jailson, E-mail: campista@on.br, E-mail: micolbenetti@on.br, E-mail: alcaniz@on.br [Observatório Nacional, Rua General José Cristino 77, Rio de Janeiro, RJ, 20921-400 Brazil (Brazil)

2017-09-01

We use the most recent cosmic microwave background (CMB) data to perform a Bayesian statistical analysis and discuss the observational viability of inflationary models with a non-minimal coupling, ξ, between the inflaton field and the Ricci scalar. We particularize our analysis to two examples of small and large field inflationary models, namely, the Coleman-Weinberg and the chaotic quartic potentials. We find that ( i ) the ξ parameter is closely correlated with the primordial amplitude ; ( ii ) although improving the agreement with the CMB data in the r − n {sub s} plane, where r is the tensor-to-scalar ratio and n {sub s} the primordial spectral index, a non-null coupling is strongly disfavoured with respect to the minimally coupled standard ΛCDM model, since the upper bounds of the Bayes factor (odds) for ξ parameter are greater than 150:1.

Total CMB analysis of streaker aerosol samples by PIXE, PIGE, beta- and optical-absorption analyses

International Nuclear Information System (INIS)

Annegarn, H.J.; Przybylowicz, W.J.

1993-01-01

Multielemental analyses of aerosol samples are widely used in air pollution receptor modelling. Specifically, the chemical mass balance (CMB) model has become a powerful tool in urban air quality studies. Input data required for the CMB includes not only the traditional X-ray fluorescence (and hence PIXE) detected elements, but also total mass, organic and inorganic carbon, and other light elements including Mg, Na and F. The circular streaker sampler, in combination with PIXE analysis, has developed into a powerful tool for obtaining time-resolved, multielemental aerosol data. However, application in CMB modelling has been limited by the absence of total mass and complementary light element data. This study reports on progress in using techniques complementary to PIXE to obtain additional data from circular streaker samples, maintaining the nondestructive, instrumental approach inherent in PIXE: Beta-gauging using a 147 Pm source for total mass; optical absorption for inorganic carbon; and PIGE to measure the lighter elements. (orig.)

Internal delensing of Planck CMB temperature and polarization

Energy Technology Data Exchange (ETDEWEB)

Carron, Julien [Department of Physics and Astronomy, University of Sussex, Brighton BN1 9QH (United Kingdom); Lewis, Antony; Challinor, Anthony, E-mail: j.carron@sussex.ac.uk, E-mail: Antony.Lewis@sussex.ac.uk, E-mail: a.d.challinor@ast.cam.ac.uk [Institute of Astronomy and Kavli Institute for Cosmology, Madingley Road, Cambridge, CB3 0HA (United Kingdom)

2017-05-01

We present a first internal delensing of CMB maps, both in temperature and polarization, using the public foreground-cleaned (SMICA) Planck 2015 maps. After forming quadratic estimates of the lensing potential, we use the corresponding displacement field to undo the lensing on the same data. We build differences of the delensed spectra to the original data spectra specifically to look for delensing signatures. After taking into account reconstruction noise biases in the delensed spectra, we find an expected sharpening of the power spectrum acoustic peaks with a delensing efficiency of 29 % ( TT ) 25 % ( TE ) and 22 % ( EE ). The detection significance of the delensing effects is very high in all spectra: 12 σ in EE polarization; 18 σ in TE ; and 20 σ in TT . The null hypothesis of no lensing in the maps is rejected at 26 σ. While direct detection of the power in lensing B -modes themselves is not possible at high significance at Planck noise levels, we do detect (at 4.5 σ (under the null hypothesis)) delensing effects in the B -mode map, with 7 % reduction in lensing power. Our results provide a first demonstration of polarization delensing, and generally of internal CMB delensing, and stand in agreement with the baseline ΛCDM Planck 2015 cosmology expectations.

Planck CMB anomalies: astrophysical and cosmological secondary effects and the curse of masking

International Nuclear Information System (INIS)

Rassat, A.; Starck, J.-L.; Paykari, P.; Sureau, F.; Bobin, J.

2014-01-01

Large-scale anomalies have been reported in CMB data with both WMAP and Planck data. These could be due to foreground residuals and or systematic effects, though their confirmation with Planck data suggests they are not due to a problem in the WMAP or Planck pipelines. If these anomalies are in fact primordial, then understanding their origin is fundamental to either validate the standard model of cosmology or to explore new physics. We investigate three other possible issues: 1) the trade-off between minimising systematics due to foreground contamination (with a conservative mask) and minimising systematics due to masking, 2) astrophysical secondary effects (the kinetic Doppler quadrupole and kinetic Sunyaev-Zel'dovich effect), and 3) secondary cosmological signals (the integrated Sachs-Wolfe effect). We address the masking issue by considering new procedures that use both WMAP and Planck to produce higher quality full-sky maps using the sparsity methodology (LGMCA maps). We show the impact of masking is dominant over that of residual foregrounds, and the LGMCA full-sky maps can be used without further processing to study anomalies. We consider four official Planck PR1 and two LGMCA CMB maps. Analysis of the observed CMB maps shows that only the low quadrupole and quadrupole-octopole alignment seem significant, but that the planar octopole, Axis of Evil, mirror parity and cold spot are not significant in nearly all maps considered. After subtraction of astrophysical and cosmological secondary effects, only the low quadrupole may still be considered anomalous, meaning the significance of only one anomaly is affected by secondary effect subtraction out of six anomalies considered. In the spirit of reproducible research all reconstructed maps and codes will be made available for download here http://www.cosmostat.org/anomaliesCMB.html

Planck CMB anomalies: astrophysical and cosmological secondary effects and the curse of masking

Energy Technology Data Exchange (ETDEWEB)

Rassat, A. [Laboratoire d' Astrophysique (LASTRO), École Polytechnique Fédérale de Lausanne (EPFL), 51 Chemin des Maillettes, Observatoire de Sauverny, Versoix, CH-1290 (Switzerland); Starck, J.-L.; Paykari, P.; Sureau, F.; Bobin, J., E-mail: anais.rassat@epfl.ch, E-mail: jstarck@cea.fr, E-mail: paniez.paykari@cea.fr, E-mail: florent.sureau@cea.fr, E-mail: jbobin@cea.fr [Laboratoire AIM, UMR CEA-CNRS-Paris, Irfu, SAp, CEA Saclay, Gif-Sur-Yvette Cedex, F-91191 France (France)

2014-08-01

Large-scale anomalies have been reported in CMB data with both WMAP and Planck data. These could be due to foreground residuals and or systematic effects, though their confirmation with Planck data suggests they are not due to a problem in the WMAP or Planck pipelines. If these anomalies are in fact primordial, then understanding their origin is fundamental to either validate the standard model of cosmology or to explore new physics. We investigate three other possible issues: 1) the trade-off between minimising systematics due to foreground contamination (with a conservative mask) and minimising systematics due to masking, 2) astrophysical secondary effects (the kinetic Doppler quadrupole and kinetic Sunyaev-Zel'dovich effect), and 3) secondary cosmological signals (the integrated Sachs-Wolfe effect). We address the masking issue by considering new procedures that use both WMAP and Planck to produce higher quality full-sky maps using the sparsity methodology (LGMCA maps). We show the impact of masking is dominant over that of residual foregrounds, and the LGMCA full-sky maps can be used without further processing to study anomalies. We consider four official Planck PR1 and two LGMCA CMB maps. Analysis of the observed CMB maps shows that only the low quadrupole and quadrupole-octopole alignment seem significant, but that the planar octopole, Axis of Evil, mirror parity and cold spot are not significant in nearly all maps considered. After subtraction of astrophysical and cosmological secondary effects, only the low quadrupole may still be considered anomalous, meaning the significance of only one anomaly is affected by secondary effect subtraction out of six anomalies considered. In the spirit of reproducible research all reconstructed maps and codes will be made available for download here http://www.cosmostat.org/anomaliesCMB.html.

Comparison of distance information given by SN Ia, BAO and CMB

International Nuclear Information System (INIS)

Li Hong

2011-01-01

The observations of Type Ia supernovae (SN Ia), Baryon Acoustic Oscillations (BAO) and Cosmic Microwave Background radiation (CMB) provide powerful tools for the measurement of cosmological parameters. One of the most useful information encodes in the distance measured by those probes. In this Letter, we test the coherence of the observational information provided by SN Ia, BAO and CMB experiments. We make two kinds of comparison: the first is the constraints on cosmological parameters of the equation of state parameter (EoS) of dark energy (DE) and matter budget parameter Ω m from the latest data by global fitting, and we find the large discrepancy from those different probes. The second comparison is performed among the derived distance information from these observations at certain appointed redshift, the results show that the distance provided by WMAP5 are larger than those from SN Ia and BAO on the whole.

Gone with the heat: a fundamental constraint on the imaging of dust and molecular gas in the early Universe.

Science.gov (United States)

Zhang, Zhi-Yu; Papadopoulos, Padelis P; Ivison, R J; Galametz, Maud; Smith, M W L; Xilouris, Emmanuel M

2016-06-01

Images of dust continuum and carbon monoxide (CO) line emission are powerful tools for deducing structural characteristics of galaxies, such as disc sizes, H2 gas velocity fields and enclosed H2 and dynamical masses. We report on a fundamental constraint set by the cosmic microwave background (CMB) on the observed structural and dynamical characteristics of galaxies, as deduced from dust continuum and CO-line imaging at high redshifts. As the CMB temperature rises in the distant Universe, the ensuing thermal equilibrium between the CMB and the cold dust and H2 gas progressively erases all spatial and spectral contrasts between their brightness distributions and the CMB. For high-redshift galaxies, this strongly biases the recoverable H2 gas and dust mass distributions, scale lengths, gas velocity fields and dynamical mass estimates. This limitation is unique to millimetre/submillimetre wavelengths and unlike its known effect on the global dust continuum and molecular line emission of galaxies, it cannot be addressed simply. We nevertheless identify a unique signature of CMB-affected continuum brightness distributions, namely an increasing rather than diminishing contrast between such brightness distributions and the CMB when the cold dust in distant galaxies is imaged at frequencies beyond the Raleigh-Jeans limit. For the molecular gas tracers, the same effect makes the atomic carbon lines maintain a larger contrast than the CO lines against the CMB.

Constraining resonant photon-axion conversions in the Early Universe

Energy Technology Data Exchange (ETDEWEB)

Mirizzi, Alessandro [Max-Planck-Inst. fuer Physik (Werner-Heisenberg-Inst.), Muenchen (Germany); Redondo, Javier [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Sigl, Guenter [Hamburg Univ. (Germany). II. Inst. fuer Theoretische Physik

2009-05-15

The presence of a primordial magnetic field would have induced resonant conversions between photons and axion-like particles (ALPs) during the thermal history of the Universe. These conversions would have distorted the blackbody spectrum of the cosmic microwave background (CMB). In this context, we derive bounds on the photon-ALP resonant conversions using the high precision CMB spectral data collected by the FIRAS instrument on board of the Cosmic Background Explorer. We obtain upper limits on the product of the photon-ALP coupling constant g times the magnetic field strength B down to gB

On the determination of neutrino masses and dark energy evolution from the cross-correlation of CMB and LSS

International Nuclear Information System (INIS)

Ichikawa, Kazuhide; Takahashi, Tomo

2008-01-01

We discuss the possibilities of the simultaneous determination of the neutrino masses and the evolution of dark energy from future cosmological observations such as cosmic microwave background (CMB), large scale structure (LSS) and the cross-correlation between them. Recently it has been discussed that there is a degeneracy between the neutrino masses and the equation of state for dark energy. It is also known that there are some degeneracies among the parameters describing the dark energy evolution. We discuss the implications of these for the cross-correlation of CMB with LSS in some detail. Then we consider to what extent we can determine the neutrino masses and the dark energy evolution using the expected data from CMB, LSS and their cross-correlation

The influence of IVF/ICSI treatment on human embryonic growth trajectories.

Science.gov (United States)

Eindhoven, S C; van Uitert, E M; Laven, J S E; Willemsen, S P; Koning, A H J; Eilers, P H C; Exalto, N; Steegers, E A P; Steegers-Theunissen, R P M

2014-12-01

groups (βIVF/ICSI = 6 g; P = 0.36 and βIVF/ICSI = 80 g; P = 0.24, respectively). Variations in embryonic growth trajectories of spontaneously conceived pregnancies with reliable pregnancy dating may partially be a result of less precise pregnancy dating and differences in endometrium receptivity compared with IVF/ICSI pregnancies. The absence of a significant difference in embryonic and fetal growth trajectories suggests safety of IVF/ICSI treatment with regard to early embryonic growth. However, further research is warranted to ascertain the influence of IVF/ICSI treatments in a larger study population, and to estimate the impact of the underlying causes of the subfertility and other periconceptional exposures on human embryonic and fetal growth trajectories. This study was supported by the Department of Obstetrics and Gynaecology of the Erasmus MC, University Medical Centre. No competing interests are declared. © The Author 2014. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Precision epoch of reionization studies with next-generation CMB experiments

Energy Technology Data Exchange (ETDEWEB)

Calabrese, Erminia; Louis, Thibaut [Sub-department of Astrophysics, University of Oxford, Keble Road, Oxford, OX1 3RH (United Kingdom); Hložek, Renée; Hil, J. Colin [Department of Astrophysical Science, Peyton Hall, 4 Ivy Lane, Princeton, NJ, 08544 (United States); Battaglia, Nick [McWilliams Center for Cosmology, Department of Physics, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, PA, 15213 (United States); Bond, J. Richard; Hajian, Amir [Canadian Institute for Theoretical Astrophysics, University of Toronto, 60 St George Street, Toronto, ON, M5S 3H8 Canada (Canada); De Bernardis, Francesco; Henderson, Shawn; Niemack, Michael D. [Department of Physics, Cornell University, 109 Clark Hall, Ithaca, NY, 14853 (United States); Devlin, Mark J. [Department of Physics and Astronomy, University of Pennsylvania, 209 South 33rd Street, Philadelphia, PA, 19104 (United States); Kosowsky, Arthur [Department of Physics and Astronomy, University of Pittsburgh, 315 Allen Hall, Pittsburgh, PA, 15260 (United States); McMahon, Jeff [Department of Physics, University of Michigan, 450 Church Street, Ann Arbor, MI, 48109 (United States); Moodley, Kavilan [Astrophysics and Cosmology Research Unit, School of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Westville Campus, Private Bag X54001, Durban, 4041 South Africa (South Africa); Newburgh, Laura [Dunlap Institute for Astronomy and Astrophysics, University of Toronto, 50 St. George St., Toronto, ON, M5S 3H4 Canada (Canada); Page, Lyman A. [Joseph Henry Laboratories of Physics, Jadwin Hall, Princeton University, Washington Road, Princeton, NJ, 08544 (United States); Partridge, Bruce [Department of Physics and Astronomy, Haverford College, 370 Lancaster Avenue, Haverford, PA, 19041 (United States); Sehgal, Neelima, E-mail: erminia.calabrese@astro.ox.ac.uk, E-mail: rhlozek@astro.princeton.edu [Physics and Astronomy Department, Stony Brook University, Stony Brook, NY, 11794 (United States); and others

2014-08-01

Future arcminute resolution polarization data from ground-based Cosmic Microwave Background (CMB) observations can be used to estimate the contribution to the temperature power spectrum from the primary anisotropies and to uncover the signature of reionization near ℓ=1500 in the small angular-scale temperature measurements. Our projections are based on combining expected small-scale E-mode polarization measurements from Advanced ACTPol in the range 300<ℓ<3000 with simulated temperature data from the full Planck mission in the low and intermediate ℓ region, 2<ℓ<2000. We show that the six basic cosmological parameters determined from this combination of data will predict the underlying primordial temperature spectrum at high multipoles to better than 1% accuracy. Assuming an efficient cleaning from multi-frequency channels of most foregrounds in the temperature data, we investigate the sensitivity to the only residual secondary component, the kinematic Sunyaev-Zel'dovich (kSZ) term. The CMB polarization is used to break degeneracies between primordial and secondary terms present in temperature and, in effect, to remove from the temperature data all but the residual kSZ term. We estimate a 15σ detection of the diffuse homogeneous kSZ signal from expected AdvACT temperature data at ℓ>1500, leading to a measurement of the amplitude of matter density fluctuations, σ{sub 8}, at 1% precision. Alternatively, by exploring the reionization signal encoded in the patchy kSZ measurements, we bound the time and duration of the reionization with σ(z{sub re})=1.1 and σ(Δz{sub re})=0.2. We find that these constraints degrade rapidly with large beam sizes, which highlights the importance of arcminute-scale resolution for future CMB surveys.

Growth trajectories of the human embryonic head and periconceptional maternal conditions.

Science.gov (United States)

Koning, I V; Baken, L; Groenenberg, I A L; Husen, S C; Dudink, J; Willemsen, S P; Gijtenbeek, M; Koning, A H J; Reiss, I K M; Steegers, E A P; Steegers-Theunissen, R P M

2016-05-01

Can growth trajectories of the human embryonic head be created using 3D ultrasound (3D-US) and virtual reality (VR) technology, and be associated with second trimester fetal head size and periconceptional maternal conditions? Serial first trimester head circumference (HC) and head volume (HV) measurements were used to create reliable growth trajectories of the embryonic head, which were significantly associated with fetal head size and periconceptional maternal smoking, age and ITALIC! in vitro fertilization (IVF)/intra-cytoplasmic sperm injection (ICSI) treatment. Fetal growth is influenced by periconceptional maternal conditions. We selected 149 singleton pregnancies with a live born non-malformed fetus from the Rotterdam periconception cohort. Bi-parietal diameter and occipital frontal diameter to calculate HC, HV and crown-rump length (CRL) were measured weekly between 9 + 0 and 12 + 6 weeks gestational age (GA) using 3D-US and VR. Fetal HC was obtained from second trimester structural anomaly scans. Growth trajectories of the embryonic head were created with general additive models and linear mixed models were used to estimate associations with maternal periconceptional conditions as a function of GA and CRL, respectively. A total of 303 3D-US images of 149 pregnancies were eligible for embryonic head measurements (intra-class correlation coefficients >0.99). Associations were found between embryonic HC and fetal HC ( ITALIC! ρ = 0.617, ITALIC! P head measured by HC and HV (All ITALIC! P head may be of benefit in future early antenatal care. This study was funded by the Department of Obstetrics and Gynaecology, Erasmus MC University Medical Centre and Sophia Foundation for Medical Research, Rotterdam, The Netherlands (SSWO grant number 644). No competing interests are declared. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email

Superweakly interacting massive particle dark matter signals from the early Universe

International Nuclear Information System (INIS)

Feng, Jonathan L.; Rajaraman, Arvind; Takayama, Fumihiro

2003-01-01

Cold dark matter may be made of superweakly interacting massive particles, super-WIMP's, that naturally inherit the desired relic density from late decays of metastable WIMP's. Well-motivated examples are weak-scale gravitinos in supergravity and Kaluza-Klein gravitons from extra dimensions. These particles are impossible to detect in all dark matter experiments. We find, however, that super-WIMP dark matter may be discovered through cosmological signatures from the early Universe. In particular, super-WIMP dark matter has observable consequences for big bang nucleosynthesis and the cosmic microwave background (CMB), and may explain the observed underabundance of 7 Li without upsetting the concordance between deuterium and CMB baryometers. We discuss the implications for future probes of CMB blackbody distortions and collider searches for new particles. In the course of this study, we also present a model-independent analysis of entropy production from late-decaying particles in light of Wilkinson microwave anisotropy probe data

The BAHAMAS project: the CMB-large-scale structure tension and the roles of massive neutrinos and galaxy formation

Science.gov (United States)

McCarthy, Ian G.; Bird, Simeon; Schaye, Joop; Harnois-Deraps, Joachim; Font, Andreea S.; van Waerbeke, Ludovic

2018-05-01

Recent studies have presented evidence for tension between the constraints on Ωm and σ8 from the cosmic microwave background (CMB) and measurements of large-scale structure (LSS). This tension can potentially be resolved by appealing to extensions of the standard model of cosmology and/or untreated systematic errors in the modelling of LSS, of which baryonic physics has been frequently suggested. We revisit this tension using, for the first time, carefully calibrated cosmological hydrodynamical simulations, which thus capture the backreaction of the baryons on the total matter distribution. We have extended the BAryons and HAloes of MAssive Sysmtes simulations to include a treatment of massive neutrinos, which currently represents the best-motivated extension to the standard model. We make synthetic thermal Sunyaev-Zel'dovich effect, weak galaxy lensing, and CMB lensing maps and compare to observed auto- and cross-power spectra from a wide range of recent observational surveys. We conclude that: (i) in general, there is tension between the primary CMB and LSS when adopting the standard model with minimal neutrino mass; (ii) after calibrating feedback processes to match the gas fractions of clusters, the remaining uncertainties in the baryonic physics modelling are insufficient to reconcile this tension; and (iii) if one accounts for internal tensions in the Planck CMB data set (by allowing the lensing amplitude, ALens, to vary), invoking a non-minimal neutrino mass, typically of 0.2-0.4 eV, can resolve the tension. This solution is fully consistent with separate constraints from the primary CMB and baryon acoustic oscillations.

Large-angle cosmic microwave background anisotropies in an open universe

Science.gov (United States)

Kamionkowski, Marc; Spergel, David N.

1994-01-01

If the universe is open, scales larger than the curvature scale may be probed by observation of large-angle fluctuations in the cosmic microwave background (CMB). We consider primordial adiabatic perturbations and discuss power spectra that are power laws in volume, wavelength, and eigenvalue of the Laplace operator. Such spectra may have arisen if, for example, the universe underwent a period of `frustated' inflation. The resulting large-angle anisotropies of the CMB are computed. The amplitude generally increases as Omega is decreased but decreases as h is increased. Interestingly enough, for all three Ansaetze, anisotropies on angular scales larger than the curvature scale are suppressed relative to the anisotropies on scales smaller than the curvature scale, but cosmic variance makes discrimination between various models difficult. Models with 0.2 approximately less than Omega h approximately less than 0.3 appear compatible with CMB fluctuations detected by Cosmic Background Explorer Satellite (COBE) and the Tenerife experiment and with the amplitude and spectrum of fluctuations of galaxy counts in the APM, CfA, and 1.2 Jy IRAS surveys. COBE normalization for these models yields sigma(sub 8) approximately = 0.5 - 0.7. Models with smaller values of Omega h when normalized to COBE require bias factors in excess of 2 to be compatible with the observed galaxy counts on the 8/h Mpc scale. Requiring that the age of the universe exceed 10 Gyr implies that Omega approximately greater than 0.25, while requiring that from the last-scattering term in the Sachs-Wolfe formula, large-angle anisotropies come primarily from the decay of potential fluctuations at z approximately less than 1/Omega. Thus, if the universe is open, COBE has been detecting temperature fluctuations produced at moderate redshift rather than at z approximately 1300.

WMAP - A Glimpse of the Early Universe

Science.gov (United States)

Wollack, Edward

2009-01-01

The early Universe was incredibly hot, dense, and homogeneous. A powerful probe of this time is provided by the relic radiation which we refer to today as the Cosmic Microwave Background (CMB). Images produced from this light contain the earliest glimpse of the Universe after the "Big Bang" and the signature of the evolution of its contents. By exploiting these clues, precise constraints on the age, mass density, and geometry of the early Universe can be derived. The history of this intriguing cosmological detective story will be reviewed. Recent results from NASA's Wilkinson Microwave Anisotropy Probe (WMAP) will be presented.

Using Big Bang Nucleosynthesis to extend CMB probes of neutrino physics

Energy Technology Data Exchange (ETDEWEB)

Shimon, M.; Miller, N.J.; Fuller, G.M.; Keating, B.G. [Center for Astrophysics and Space Sciences, University of California, San Diego, La Jolla, CA, 92093 (United States); Kishimoto, C.T. [Department of Physics and Astronomy, University of California, Los Angeles, CA, 90095 (United States); Smith, C.J., E-mail: meirs@mamacass.ucsd.edu, E-mail: nmiller@physics.ucsd.edu, E-mail: ckishimo@physics.ucsd.edu, E-mail: christel.smith@asu.edu, E-mail: gfuller@ucsd.edu, E-mail: bkeating@ucsd.edu [Department of Physics, Arizona State University, Tempe, AZ, 85287 (United States)

2010-05-01

We present calculations showing that upcoming Cosmic Microwave Background (CMB) experiments will have the power to improve on current constraints on neutrino masses and provide new limits on neutrino degeneracy parameters. The latter could surpass those derived from Big Bang Nucleosynthesis (BBN) and the observationally-inferred primordial helium abundance. These conclusions derive from our Monte Carlo Markov Chain (MCMC) simulations which incorporate a full BBN nuclear reaction network. This provides a self-consistent treatment of the helium abundance, the baryon number, the three individual neutrino degeneracy parameters and other cosmological parameters. Our analysis focuses on the effects of gravitational lensing on CMB constraints on neutrino rest mass and degeneracy parameter. We find for the PLANCK experiment that total (summed) neutrino mass M{sub ν} > 0.29 eV could be ruled out at 2σ or better. Likewise neutrino degeneracy parameters ξ{sub ν{sub e}} > 0.11 and |ξ{sub ν{sub μ{sub /{sub τ}}}}| > 0.49 could be detected or ruled out at 2σ confidence, or better. For POLARBEAR we find that the corresponding detectable values are M{sub ν} > 0.75 eV, ξ{sub ν{sub e}} > 0.62, and |ξ{sub ν{sub μ{sub /{sub τ}}}}| > 1.1, while for EPIC we obtain M{sub ν} > 0.20 eV, ξ{sub ν{sub e}} > 0.045, and |ξ{sub ν{sub μ{sub /{sub τ}}}}| > 0.29. Our forcast for EPIC demonstrates that CMB observations have the potential to set constraints on neutrino degeneracy parameters which are better than BBN-derived limits and an order of magnitude better than current WMAP-derived limits.

Planck 2015 results: XVI. Isotropy and statistics of the CMB

DEFF Research Database (Denmark)

Ade, P. A R; Aghanim, N.; Akrami, Y.

2016-01-01

We test the statistical isotropy and Gaussianity of the cosmic microwave background (CMB) anisotropies using observations made by the Planck satellite. Our results are based mainly on the full Planck mission for temperature, but also include some polarization measurements. In particular, we consi...

INTRODUCING MEXICAN NEEDLETS FOR CMB ANALYSIS: ISSUES FOR PRACTICAL APPLICATIONS AND COMPARISON WITH STANDARD NEEDLETS

International Nuclear Information System (INIS)

Scodeller, S.; Rudjord, Oe.; Hansen, F. K.; Marinucci, D.; Geller, D.; Mayeli, A.

2011-01-01

Over the last few years, needlets have emerged as a useful tool for the analysis of cosmic microwave background (CMB) data. Our aim in this paper is first to introduce into the CMB literature a different form of needlets, known as Mexican needlets, first discussed in the mathematical literature by Geller and Mayeli. We then proceed with an extensive study of the properties of both standard and Mexican needlets; these properties depend on some parameters which can be tuned in order to optimize the performance for a given application. Our second aim in this paper is then to give practical advice on how to adjust these parameters for WMAP and Planck data in order to achieve the best properties for a given problem in CMB data analysis. In particular, we investigate localization properties in real and harmonic space and propose a recipe for quantifying the influence of galactic and point-source masks on the needlet coefficients. We also show that for certain parameter values, the Mexican needlets provide a close approximation to the Spherical Mexican Hat Wavelets (whence their name), with some advantages concerning their numerical implementation and derivation of their statistical properties.

An analytical approach to the CMB polarization in a spatially closed background

Science.gov (United States)

Niazy, Pedram; Abbassi, Amir H.

2018-03-01

The scalar mode polarization of the cosmic microwave background is derived in a spatially closed universe from the Boltzmann equation using the line of sight integral method. The EE and TE multipole coefficients have been extracted analytically by considering some tolerable approximations such as considering the evolution of perturbation hydrodynamically and sudden transition from opacity to transparency at the time of last scattering. As the major advantage of analytic expressions, CEE,ℓS and CTE,ℓ explicitly show the dependencies on baryon density ΩB, matter density ΩM, curvature ΩK, primordial spectral index ns, primordial power spectrum amplitude As, Optical depth τreion, recombination width σt and recombination time tL. Using a realistic set of cosmological parameters taken from a fit to data from Planck, the closed universe EE and TE power spectrums in the scalar mode are compared with numerical results from the CAMB code and also latest observational data. The analytic results agree with the numerical ones on the big and moderate scales. The peak positions are in good agreement with the numerical result on these scales while the peak heights agree with that to within 20% due to the approximations have been considered for these derivations. Also, several interesting properties of CMB polarization are revealed by the analytic spectra.

A Measurement of the Angular Power Spectrum of the CMB from l = 100 to 400

Science.gov (United States)

Miller, A. D.; Caldwell, R.; Devlin, M. J.; Dorwart, W. B.; Herbig, T.; Nolta, M. R.; Page, L. A.; Puchalla, J.; Torbet, E.; Tran, H. T.

2000-05-01

We report on a measurement of the angular spectrum of the CMB between l 100 and l 400 made at 144 GHz from Cerro Toco in the Chilean altiplano. When the new data are combined with previous data at 30 and 40 GHz, taken with the same instrument observing the same section of sky, we find: 1) a rise in the angular spectrum to a maximum with δ Tl 85 μ K at l 200 and a fall at l>300, thereby localizing the peak near l 200; and 2) that the anisotropy at l 200 has the spectrum of the CMB. Cosmological implications are discussed.

Measuring the anisotropy in the CMB

Science.gov (United States)

Page, L. A.

The CMB is perhaps the cleanest cosmological observable. Its angular spectrum may be both computed and measured to percent accuracy. The current data clearly show a rise in the angular spectrum to a peak of roughly Tl = (l(l + 1)Cl/2)1/2 80 K at l 200, and a fall at higher l. In particular, δTl at l = 400 is significantly less than at l = 200. This is shown through a combined analysis of data sets and by the TOCO data alone. For spatially flat models, a peak in the angular spectrum near l = 200 is indicated, whereas for Ω0 = 0.35 models one expects a peak near l = 400. The data clearly prefer the spatially flat models.

Planck 2013 results. XV. CMB power spectra and likelihood

Science.gov (United States)

Planck Collaboration; Ade, P. A. R.; Aghanim, N.; Armitage-Caplan, C.; Arnaud, M.; Ashdown, M.; Atrio-Barandela, F.; Aumont, J.; Baccigalupi, C.; Banday, A. J.; Barreiro, R. B.; Bartlett, J. G.; Battaner, E.; Benabed, K.; Benoît, A.; Benoit-Lévy, A.; Bernard, J.-P.; Bersanelli, M.; Bielewicz, P.; Bobin, J.; Bock, J. J.; Bonaldi, A.; Bonavera, L.; Bond, J. R.; Borrill, J.; Bouchet, F. R.; Boulanger, F.; Bridges, M.; Bucher, M.; Burigana, C.; Butler, R. C.; Calabrese, E.; Cardoso, J.-F.; Catalano, A.; Challinor, A.; Chamballu, A.; Chiang, H. C.; Chiang, L.-Y.; Christensen, P. R.; Church, S.; Clements, D. L.; Colombi, S.; Colombo, L. P. L.; Combet, C.; Couchot, F.; Coulais, A.; Crill, B. P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R. D.; Davis, R. J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Delouis, J.-M.; Désert, F.-X.; Dickinson, C.; Diego, J. M.; Dole, H.; Donzelli, S.; Doré, O.; Douspis, M.; Dunkley, J.; Dupac, X.; Efstathiou, G.; Elsner, F.; Enßlin, T. A.; Eriksen, H. K.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A. A.; Franceschi, E.; Gaier, T. C.; Galeotta, S.; Galli, S.; Ganga, K.; Giard, M.; Giardino, G.; Giraud-Héraud, Y.; Gjerløw, E.; González-Nuevo, J.; Górski, K. M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J. E.; Hansen, F. K.; Hanson, D.; Harrison, D.; Helou, G.; Henrot-Versillé, S.; Hernández-Monteagudo, C.; Herranz, D.; Hildebrandt, S. R.; Hivon, E.; Hobson, M.; Holmes, W. A.; Hornstrup, A.; Hovest, W.; Huffenberger, K. M.; Hurier, G.; Jaffe, A. H.; Jaffe, T. R.; Jewell, J.; Jones, W. C.; Juvela, M.; Keihänen, E.; Keskitalo, R.; Kiiveri, K.; Kisner, T. S.; Kneissl, R.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lähteenmäki, A.; Lamarre, J.-M.; Lasenby, A.; Lattanzi, M.; Laureijs, R. J.; Lawrence, C. R.; Le Jeune, M.; Leach, S.; Leahy, J. P.; Leonardi, R.; León-Tavares, J.; Lesgourgues, J.; Liguori, M.; Lilje, P. B.; Linden-Vørnle, M.; Lindholm, V.; López-Caniego, M.; Lubin, P. M.; Macías-Pérez, J. F.; Maffei, B.; Maino, D.; Mandolesi, N.; Marinucci, D.; Maris, M.; Marshall, D. J.; Martin, P. G.; Martínez-González, E.; Masi, S.; Massardi, M.; Matarrese, S.; Matthai, F.; Mazzotta, P.; Meinhold, P. R.; Melchiorri, A.; Mendes, L.; Menegoni, E.; Mennella, A.; Migliaccio, M.; Millea, M.; Mitra, S.; Miville-Deschênes, M.-A.; Molinari, D.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Moss, A.; Munshi, D.; Murphy, J. A.; Naselsky, P.; Nati, F.; Natoli, P.; Netterfield, C. B.; Nørgaard-Nielsen, H. U.; Noviello, F.; Novikov, D.; Novikov, I.; O'Dwyer, I. J.; Orieux, F.; Osborne, S.; Oxborrow, C. A.; Paci, F.; Pagano, L.; Pajot, F.; Paladini, R.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Paykari, P.; Perdereau, O.; Perotto, L.; Perrotta, F.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Popa, L.; Poutanen, T.; Pratt, G. W.; Prézeau, G.; Prunet, S.; Puget, J.-L.; Rachen, J. P.; Rahlin, A.; Rebolo, R.; Reinecke, M.; Remazeilles, M.; Renault, C.; Ricciardi, S.; Riller, T.; Ringeval, C.; Ristorcelli, I.; Rocha, G.; Rosset, C.; Roudier, G.; Rowan-Robinson, M.; Rubiño-Martín, J. A.; Rusholme, B.; Sandri, M.; Sanselme, L.; Santos, D.; Savini, G.; Scott, D.; Seiffert, M. D.; Shellard, E. P. S.; Spencer, L. D.; Starck, J.-L.; Stolyarov, V.; Stompor, R.; Sudiwala, R.; Sureau, F.; Sutton, D.; Suur-Uski, A.-S.; Sygnet, J.-F.; Tauber, J. A.; Tavagnacco, D.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Tucci, M.; Tuovinen, J.; Türler, M.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Varis, J.; Vielva, P.; Villa, F.; Vittorio, N.; Wade, L. A.; Wandelt, B. D.; Wehus, I. K.; White, M.; White, S. D. M.; Yvon, D.; Zacchei, A.; Zonca, A.

2014-11-01

This paper presents the Planck 2013 likelihood, a complete statistical description of the two-point correlation function of the CMB temperature fluctuations that accounts for all known relevant uncertainties, both instrumental and astrophysical in nature. We use this likelihood to derive our best estimate of the CMB angular power spectrum from Planck over three decades in multipole moment, ℓ, covering 2 ≤ ℓ ≤ 2500. The main source of uncertainty at ℓ ≲ 1500 is cosmic variance. Uncertainties in small-scale foreground modelling and instrumental noise dominate the error budget at higher ℓs. For ℓ impact of residual foreground and instrumental uncertainties on the final cosmological parameters. We find good internal agreement among the high-ℓ cross-spectra with residuals below a few μK2 at ℓ ≲ 1000, in agreement with estimated calibration uncertainties. We compare our results with foreground-cleaned CMB maps derived from all Planck frequencies, as well as with cross-spectra derived from the 70 GHz Planck map, and find broad agreement in terms of spectrum residuals and cosmological parameters. We further show that the best-fit ΛCDM cosmology is in excellent agreement with preliminary PlanckEE and TE polarisation spectra. We find that the standard ΛCDM cosmology is well constrained by Planck from the measurements at ℓ ≲ 1500. One specific example is the spectral index of scalar perturbations, for which we report a 5.4σ deviation from scale invariance, ns = 1. Increasing the multipole range beyond ℓ ≃ 1500 does not increase our accuracy for the ΛCDM parameters, but instead allows us to study extensions beyond the standard model. We find no indication of significant departures from the ΛCDM framework. Finally, we report a tension between the Planck best-fit ΛCDM model and the low-ℓ spectrum in the form of a power deficit of 5-10% at ℓ ≲ 40, with a statistical significance of 2.5-3σ. Without a theoretically motivated model for

Adapted Method for Separating Kinetic SZ Signal from Primary CMB Fluctuations

Directory of Open Access Journals (Sweden)

Forni Olivier

2005-01-01

Full Text Available In this first attempt to extract a map of the kinetic Sunyaev-Zel'dovich (KSZ temperature fluctuations from the cosmic microwave background (CMB anisotropies, we use a method which is based on simple and minimal assumptions. We first focus on the intrinsic limitations of the method due to the cosmological signal itself. We demonstrate using simulated maps that the KSZ reconstructed maps are in quite good agreement with the original input signal with a correlation coefficient between original and reconstructed maps of on average, and an error on the standard deviation of the reconstructed KSZ map of only % on average. To achieve these results, our method is based on the fact that some first-step component separation provides us with (i a map of Compton parameters for the thermal Sunyaev-Zel'dovich (TSZ effect of galaxy clusters, and (ii a map of temperature fluctuations which is the sum of primary CMB and KSZ signals. Our method takes benefit from the spatial correlation between KSZ and TSZ effects which are both due to the same galaxy clusters. This correlation allows us to use the TSZ map as a spatial template in order to mask, in the map, the pixels where the clusters must have imprinted an SZ fluctuation. In practice, a series of TSZ thresholds is defined and for each threshold, we estimate the corresponding KSZ signal by interpolating the CMB fluctuations on the masked pixels. The series of estimated KSZ maps is finally used to reconstruct the KSZ map through the minimisation of a criterion taking into account two statistical properties of the KSZ signal (KSZ dominates over primary anisotropies at small scales, KSZ fluctuations are non-Gaussian distributed. We show that the results are quite sensitive to the effect of beam convolution, especially for large beams, and to the corruption by instrumental noise.

Slow-roll inflation and BB-mode angular power spectrum of CMB

Energy Technology Data Exchange (ETDEWEB)

Malsawmtluangi, N.; Suresh, P.K. [University of Hyderabad, School of Physics, Hyderabad (India)

2016-05-15

The BB-mode correlation angular power spectrum of CMB is obtained by considering the primordial gravitational waves in the squeezed vacuum state for various inflationary models and results are compared with the joint analysis of the BICEP2/Keck Array and Planck 353 GHz data. The present results may constrain several models of inflation. (orig.)

MAPCUMBA: A fast iterative multi-grid map-making algorithm for CMB experiments

Science.gov (United States)

Doré, O.; Teyssier, R.; Bouchet, F. R.; Vibert, D.; Prunet, S.

2001-07-01

The data analysis of current Cosmic Microwave Background (CMB) experiments like BOOMERanG or MAXIMA poses severe challenges which already stretch the limits of current (super-) computer capabilities, if brute force methods are used. In this paper we present a practical solution for the optimal map making problem which can be used directly for next generation CMB experiments like ARCHEOPS and TopHat, and can probably be extended relatively easily to the full PLANCK case. This solution is based on an iterative multi-grid Jacobi algorithm which is both fast and memory sparing. Indeed, if there are Ntod data points along the one dimensional timeline to analyse, the number of operations is of O (Ntod \\ln Ntod) and the memory requirement is O (Ntod). Timing and accuracy issues have been analysed on simulated ARCHEOPS and TopHat data, and we discuss as well the issue of the joint evaluation of the signal and noise statistical properties.

Testing physical models for dipolar asymmetry with CMB polarization

Science.gov (United States)

Contreras, D.; Zibin, J. P.; Scott, D.; Banday, A. J.; Górski, K. M.

2017-12-01

The cosmic microwave background (CMB) temperature anisotropies exhibit a large-scale dipolar power asymmetry. To determine whether this is due to a real, physical modulation or is simply a large statistical fluctuation requires the measurement of new modes. Here we forecast how well CMB polarization data from Planck and future experiments will be able to confirm or constrain physical models for modulation. Fitting several such models to the Planck temperature data allows us to provide predictions for polarization asymmetry. While for some models and parameters Planck polarization will decrease error bars on the modulation amplitude by only a small percentage, we show, importantly, that cosmic-variance-limited (and in some cases even Planck) polarization data can decrease the errors by considerably better than the expectation of √{2 } based on simple ℓ-space arguments. We project that if the primordial fluctuations are truly modulated (with parameters as indicated by Planck temperature data) then Planck will be able to make a 2 σ detection of the modulation model with 20%-75% probability, increasing to 45%-99% when cosmic-variance-limited polarization is considered. We stress that these results are quite model dependent. Cosmic variance in temperature is important: combining statistically isotropic polarization with temperature data will spuriously increase the significance of the temperature signal with 30% probability for Planck.

An estimator for statistical anisotropy from the CMB bispectrum

International Nuclear Information System (INIS)

Bartolo, N.; Dimastrogiovanni, E.; Matarrese, S.; Liguori, M.; Riotto, A.

2012-01-01

Various data analyses of the Cosmic Microwave Background (CMB) provide observational hints of statistical isotropy breaking. Some of these features can be studied within the framework of primordial vector fields in inflationary theories which generally display some level of statistical anisotropy both in the power spectrum and in higher-order correlation functions. Motivated by these observations and the recent theoretical developments in the study of primordial vector fields, we develop the formalism necessary to extract statistical anisotropy information from the three-point function of the CMB temperature anisotropy. We employ a simplified vector field model and parametrize the bispectrum of curvature fluctuations in such a way that all the information about statistical anisotropy is encoded in some parameters λ LM (which measure the anisotropic to the isotropic bispectrum amplitudes). For such a template bispectrum, we compute an optimal estimator for λ LM and the expected signal-to-noise ratio. We estimate that, for f NL ≅ 30, an experiment like Planck can be sensitive to a ratio of the anisotropic to the isotropic amplitudes of the bispectrum as small as 10%. Our results are complementary to the information coming from a power spectrum analysis and particularly relevant for those models where statistical anisotropy turns out to be suppressed in the power spectrum but not negligible in the bispectrum

CMB Polarization B-mode Delensing with SPTpol and Herschel

Energy Technology Data Exchange (ETDEWEB)

Manzotti, A.; et al.

2017-01-16

We present a demonstration of delensing the observed cosmic microwave background (CMB) B-mode polarization anisotropy. This process of reducing the gravitational-lensing generated B-mode component will become increasingly important for improving searches for the B modes produced by primordial gravitational waves. In this work, we delens B-mode maps constructed from multi-frequency SPTpol observations of a 90 deg$^2$ patch of sky by subtracting a B-mode template constructed from two inputs: SPTpol E-mode maps and a lensing potential map estimated from the $\\textit{Herschel}$ $500\\,\\mu m$ map of the CIB. We find that our delensing procedure reduces the measured B-mode power spectrum by 28% in the multipole range $300 < \\ell < 2300$; this is shown to be consistent with expectations from theory and simulations and to be robust against systematics. The null hypothesis of no delensing is rejected at $6.9 \\sigma$. Furthermore, we build and use a suite of realistic simulations to study the general properties of the delensing process and find that the delensing efficiency achieved in this work is limited primarily by the noise in the lensing potential map. We demonstrate the importance of including realistic experimental non-idealities in the delensing forecasts used to inform instrument and survey-strategy planning of upcoming lower-noise experiments, such as CMB-S4.

Optimized Large-scale CMB Likelihood and Quadratic Maximum Likelihood Power Spectrum Estimation

Science.gov (United States)

Gjerløw, E.; Colombo, L. P. L.; Eriksen, H. K.; Górski, K. M.; Gruppuso, A.; Jewell, J. B.; Plaszczynski, S.; Wehus, I. K.

2015-11-01

We revisit the problem of exact cosmic microwave background (CMB) likelihood and power spectrum estimation with the goal of minimizing computational costs through linear compression. This idea was originally proposed for CMB purposes by Tegmark et al., and here we develop it into a fully functioning computational framework for large-scale polarization analysis, adopting WMAP as a working example. We compare five different linear bases (pixel space, harmonic space, noise covariance eigenvectors, signal-to-noise covariance eigenvectors, and signal-plus-noise covariance eigenvectors) in terms of compression efficiency, and find that the computationally most efficient basis is the signal-to-noise eigenvector basis, which is closely related to the Karhunen-Loeve and Principal Component transforms, in agreement with previous suggestions. For this basis, the information in 6836 unmasked WMAP sky map pixels can be compressed into a smaller set of 3102 modes, with a maximum error increase of any single multipole of 3.8% at ℓ ≤ 32 and a maximum shift in the mean values of a joint distribution of an amplitude-tilt model of 0.006σ. This compression reduces the computational cost of a single likelihood evaluation by a factor of 5, from 38 to 7.5 CPU seconds, and it also results in a more robust likelihood by implicitly regularizing nearly degenerate modes. Finally, we use the same compression framework to formulate a numerically stable and computationally efficient variation of the Quadratic Maximum Likelihood implementation, which requires less than 3 GB of memory and 2 CPU minutes per iteration for ℓ ≤ 32, rendering low-ℓ QML CMB power spectrum analysis fully tractable on a standard laptop.

Cosmological birefringence constraints from CMB and astrophysical polarization data

Energy Technology Data Exchange (ETDEWEB)

Galaverni, M. [Studio Teologico Interdiocesano, V.le Timavo 93, Reggio Emilia, 42121 Italy (Italy); Gubitosi, G. [Dipartimento di Fisica and sez. Roma1 INFN, Università di Roma ' La Sapienza' , P.le A. Moro 2, Rome, 00185 Italy (Italy); Paci, F. [SISSA, Scuola Internazionale Superiore di Studi Avanzati, Via Bonomea 265, Trieste, 34136 Italy (Italy); Finelli, F., E-mail: matteo.galaverni@gmail.com, E-mail: giulia.gubitosi@imperial.ac.uk, E-mail: fpaci@sissa.it, E-mail: finelli@iasfbo.inaf.it [INAF-IASF Bologna, via Gobetti 101, Bologna, I-40129 Italy (Italy)

2015-08-01

Cosmological birefringence is a rotation of the polarization plane of photons coming from sources of astrophysical and cosmological origin. The rotation can also depend on the energy of the photons and not only on the distance of the source and on the cosmological evolution of the underlying theoretical model. In this work, we constrain few selected models for cosmological birefringence, combining CMB and astrophysical data at radio, optical, X and γ wavelengths, taking into account the specific energy and distance dependences.

Finding the chiral gravitational wave background of an axion-S U (2 ) inflationary model using CMB observations and laser interferometers

Science.gov (United States)

Thorne, Ben; Fujita, Tomohiro; Hazumi, Masashi; Katayama, Nobuhiko; Komatsu, Eiichiro; Shiraishi, Maresuke

2018-02-01

A detection of B-mode polarization of the cosmic microwave background (CMB) anisotropies would confirm the presence of a primordial gravitational wave background (GWB). In the inflation paradigm, this would be an unprecedented probe of the energy scale of inflation as it is directly proportional to the power spectrum of the GWB. However, similar tensor perturbations can be produced by the matter fields present during inflation, breaking the simple relationship between energy scale and the tensor-to-scalar ratio r . It is therefore important to find ways of distinguishing between the generation mechanisms of the GWB. Without doing a full model selection, we analyze the detectability of a new axion-S U (2 ) gauge field model by calculating the signal-to-noise ratio of future CMB and interferometer observations sensitive to the chirality of the tensor spectrum. We forecast the detectability of the resulting CMB temperature and B-mode (TB) or E-mode and B-mode (EB) cross-correlation by the LiteBIRD satellite, considering the effects of residual foregrounds, gravitational lensing, and assess the ability of such an experiment to jointly detect primordial TB and EB spectra and self-calibrate its polarimeter. We find that LiteBIRD will be able to detect the chiral signal for r*>0.03 , with r* denoting the tensor-to-scalar ratio at the peak scale, and that the maximum signal-to-noise ratio for r*advanced stage of a LISA-like mission, which is designed to be sensitive to the intensity and polarization of the GWB. We find that such experiments would complement CMB observations as they would be able to detect the chirality of the GWB with high significance on scales inaccessible to the CMB. We conclude that CMB two-point statistics are limited in their ability to distinguish this model from a conventional vacuum fluctuation model of GWB generation, due to the fundamental limits on their sensitivity to parity violation. In order to test the predictions of such a model as

CMB scale dependent non-Gaussianity from massive gravity during inflation

Energy Technology Data Exchange (ETDEWEB)

Domènech, Guillem; Hiramatsu, Takashi; Lin, Chunshan; Sasaki, Misao [Center for Gravitational Physics, Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto, 606-8502 (Japan); Shiraishi, Maresuke [Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), UTIAS, The University of Tokyo, Chiba, 277-8583 (Japan); Wang, Yi, E-mail: guillem.domenech@yukawa.kyoto-u.ac.jp, E-mail: hiramatz@yukawa.kyoto-u.ac.jp, E-mail: chunshan.lin@yukawa.kyoto-u.ac.jp, E-mail: misao@yukawa.kyoto-u.ac.jp, E-mail: shiraishi-m@t.kagawa-nct.ac.jp, E-mail: phyw@ust.hk [Department of Physics, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong (China)

2017-05-01

We consider a cosmological model in which the tensor mode becomes massive during inflation, and study the Cosmic Microwave Background (CMB) temperature and polarization bispectra arising from the mixing between the scalar mode and the massive tensor mode during inflation. The model assumes the existence of a preferred spatial frame during inflation. The local Lorentz invariance is already broken in cosmology due to the existence of a preferred rest frame. The existence of a preferred spatial frame further breaks the remaining local SO(3) invariance and in particular gives rise to a mass in the tensor mode. At linear perturbation level, we minimize our model so that the vector mode remains non-dynamical, while the scalar mode is the same as the one in single-field slow-roll inflation. At non-linear perturbation level, this inflationary massive graviton phase leads to a sizeable scalar-scalar-tensor coupling, much greater than the scalar-scalar-scalar one, as opposed to the conventional case. This scalar-scalar-tensor interaction imprints a scale dependent feature in the CMB temperature and polarization bispectra. Very intriguingly, we find a surprizing similarity between the predicted scale dependence and the scale-dependent non-Gaussianities at low multipoles hinted in the WMAP and Planck results.

Estimation of inflation parameters for Perturbed Power Law model using recent CMB measurements

International Nuclear Information System (INIS)

Mukherjee, Suvodip; Das, Santanu; Souradeep, Tarun; Joy, Minu

2015-01-01

Cosmic Microwave Background (CMB) is an important probe for understanding the inflationary era of the Universe. We consider the Perturbed Power Law (PPL) model of inflation which is a soft deviation from Power Law (PL) inflationary model. This model captures the effect of higher order derivative of Hubble parameter during inflation, which in turn leads to a non-zero effective mass m eff for the inflaton field. The higher order derivatives of Hubble parameter at leading order sources constant difference in the spectral index for scalar and tensor perturbation going beyond PL model of inflation. PPL model have two observable independent parameters, namely spectral index for tensor perturbation ν t and change in spectral index for scalar perturbation ν st to explain the observed features in the scalar and tensor power spectrum of perturbation. From the recent measurements of CMB power spectra by WMAP, Planck and BICEP-2 for temperature and polarization, we estimate the feasibility of PPL model with standard ΛCDM model. Although BICEP-2 claimed a detection of r=0.2, estimates of dust contamination provided by Planck have left open the possibility that only upper bound on r will be expected in a joint analysis. As a result we consider different upper bounds on the value of r and show that PPL model can explain a lower value of tensor to scalar ratio (r<0.1 or r<0.01) for a scalar spectral index of n s =0.96 by having a non-zero value of effective mass of the inflaton field m 2 eff /H 2 . The analysis with WP + Planck likelihood shows a non-zero detection of m 2 eff /H 2 with 5.7 σ and 8.1 σ respectively for r<0.1 and r<0.01. Whereas, with BICEP-2 likelihood m 2 eff /H 2  = −0.0237 ± 0.0135 which is consistent with zero

Measuring galaxy cluster masses with CMB lensing using a Maximum Likelihood estimator: statistical and systematic error budgets for future experiments

Energy Technology Data Exchange (ETDEWEB)

Raghunathan, Srinivasan; Patil, Sanjaykumar; Bianchini, Federico; Reichardt, Christian L. [School of Physics, University of Melbourne, 313 David Caro building, Swanston St and Tin Alley, Parkville VIC 3010 (Australia); Baxter, Eric J. [Department of Physics and Astronomy, University of Pennsylvania, 209 S. 33rd Street, Philadelphia, PA 19104 (United States); Bleem, Lindsey E. [Argonne National Laboratory, High-Energy Physics Division, 9700 S. Cass Avenue, Argonne, IL 60439 (United States); Crawford, Thomas M. [Kavli Institute for Cosmological Physics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States); Holder, Gilbert P. [Department of Astronomy and Department of Physics, University of Illinois, 1002 West Green St., Urbana, IL 61801 (United States); Manzotti, Alessandro, E-mail: srinivasan.raghunathan@unimelb.edu.au, E-mail: s.patil2@student.unimelb.edu.au, E-mail: ebax@sas.upenn.edu, E-mail: federico.bianchini@unimelb.edu.au, E-mail: bleeml@uchicago.edu, E-mail: tcrawfor@kicp.uchicago.edu, E-mail: gholder@illinois.edu, E-mail: manzotti@uchicago.edu, E-mail: christian.reichardt@unimelb.edu.au [Department of Astronomy and Astrophysics, University of Chicago, 5640 South Ellis Avenue, Chicago, IL 60637 (United States)

2017-08-01

We develop a Maximum Likelihood estimator (MLE) to measure the masses of galaxy clusters through the impact of gravitational lensing on the temperature and polarization anisotropies of the cosmic microwave background (CMB). We show that, at low noise levels in temperature, this optimal estimator outperforms the standard quadratic estimator by a factor of two. For polarization, we show that the Stokes Q/U maps can be used instead of the traditional E- and B-mode maps without losing information. We test and quantify the bias in the recovered lensing mass for a comprehensive list of potential systematic errors. Using realistic simulations, we examine the cluster mass uncertainties from CMB-cluster lensing as a function of an experiment's beam size and noise level. We predict the cluster mass uncertainties will be 3 - 6% for SPT-3G, AdvACT, and Simons Array experiments with 10,000 clusters and less than 1% for the CMB-S4 experiment with a sample containing 100,000 clusters. The mass constraints from CMB polarization are very sensitive to the experimental beam size and map noise level: for a factor of three reduction in either the beam size or noise level, the lensing signal-to-noise improves by roughly a factor of two.

Recent cosmic microwave background observations and the ionization history of the universe

International Nuclear Information System (INIS)

Hannestad, Steen; Scherrer, Robert J.

2001-01-01

Interest in nonstandard recombination scenarios has been spurred by recent cosmic microwave background (CMB) results from BOOMERANG and MAXIMA, which show an unexpectedly low second acoustic peak, resulting in a best-fit baryon density that is 50% larger than the prediction of big-bang nucleosynthesis (BBN). This apparent discrepancy can be avoided if the universe has a nonstandard ionization history in which the recombination of hydrogen is significantly delayed relative to the standard model. While future CMB observations may eliminate this discrepancy, it is useful to develop a general framework for analyzing nonstandard ionization histories. We develop such a framework, examining nonstandard models in which the hydrogen binding energy E b and the overall expression for the time rate of change of the ionized fraction of electrons are multiplied by arbitrary factors. This set of models includes a number of previously proposed models as special cases. We find a wide range of models with delayed recombination that are able to fit the CMB data with a baryon density in accordance with BBN, but there are even allowed models with earlier recombination than in the standard model. A generic prediction of these models is that the third acoustic CMB peak should be very low relative to what is found in the standard model. This is the case even for the models with earlier recombination than in the standard model, because here the third peak is lowered by an increased diffusion damping at recombination relative to the standard model. Interestingly, the specific height of the third peak depends sensitively on the model parameters, so that future CMB measurements will be able to distinguish between different nonstandard recombination scenarios

SU(2)CMB at high redshifts and the value of H0

Science.gov (United States)

Hahn, Steffen; Hofmann, Ralf

2017-07-01

We investigate a high-z cosmological model to compute the comoving sound horizon rs at baryon-velocity freeze-out towards the end of hydrogen recombination. This model assumes a replacement of the conventional cosmic microwave background (CMB) photon gas by deconfining SU(2) Yang-Mills thermodynamics, three flavours of massless neutrinos (Nν = 3) and a purely baryonic matter sector [no cold dark-matter (CDM)]. The according SU(2) temperature-redshift relation of the CMB is contrasted with recent measurements appealing to the thermal Sunyaev-Zel'dovich effect and CMB-photon absorption by molecular rotation bands or atomic hyperfine levels. Relying on a realistic simulation of the ionization history throughout recombination, we obtain z* = 1693.55 ± 6.98 and zdrag = 1812.66 ± 7.01. Due to considerable widths of the visibility functions in the solutions to the associated Boltzmann hierarchy and Euler equation, we conclude that z* and zdrag overestimate the redshifts for the respective photon and baryon-velocity freeze-out. Realistic decoupling values turn out to be zlf,* = 1554.89 ± 5.18 and zlf, drag = 1659.30 ± 5.48. With rs(zlf, drag) = (137.19 ± 0.45) Mpc and the essentially model independent extraction of rsH0 = constant from low-z data in Bernal, Verde & Riess, we obtain a good match with the value H0 = (73.24 ± 1.74) km s-1 Mpc-1 extracted in Riess et al. by appealing to Cepheid-calibrated Type Ia supernovae, new parallax measurements, stronger constraints on the Hubble flow and a refined computation of distance to NGC 4258 from maser data. We briefly comment on a possible interpolation of our high-z model, invoking percolated and unpercolated U(1) topological solitons of a Planck-scale axion field, to the phenomenologically successful low-z ΛCDM cosmology.

Planck 2013 results. XXVII. Doppler boosting of the CMB: Eppur si muove

DEFF Research Database (Denmark)

Planck Collaboration,; Aghanim, N.; Armitage-Caplan, C.

2013-01-01

Our velocity relative to the rest frame of the cosmic microwave background (CMB) generates a dipole temperature anisotropy on the sky whichhas been well measured for more than 30 years, and has an accepted amplitude of v/c = 1.23 x 10-3, or v = 369 km-1. In addition to thissignal generated by Dop...

Taking the Universe's Temperature with Spectral Distortions of the Cosmic Microwave Background.

Science.gov (United States)

Hill, J Colin; Battaglia, Nick; Chluba, Jens; Ferraro, Simone; Schaan, Emmanuel; Spergel, David N

2015-12-31

The cosmic microwave background (CMB) energy spectrum is a near-perfect blackbody. The standard model of cosmology predicts small spectral distortions to this form, but no such distortion of the sky-averaged CMB spectrum has yet been measured. We calculate the largest expected distortion, which arises from the inverse Compton scattering of CMB photons off hot, free electrons, known as the thermal Sunyaev-Zel'dovich (TSZ) effect. We show that the predicted signal is roughly one order of magnitude below the current bound from the COBE-FIRAS experiment, but it can be detected at enormous significance (≳1000σ) by the proposed Primordial Inflation Explorer (PIXIE). Although cosmic variance reduces the effective signal-to-noise ratio to 230σ, this measurement will still yield a subpercent constraint on the total thermal energy of electrons in the observable Universe. Furthermore, we show that PIXIE can detect subtle relativistic effects in the sky-averaged TSZ signal at 30σ, which directly probe moments of the optical depth-weighted intracluster medium electron temperature distribution. These effects break the degeneracy between the electron density and the temperature in the mean TSZ signal, allowing a direct inference of the mean baryon density at low redshift. Future spectral distortion probes will thus determine the global thermodynamic properties of ionized gas in the Universe with unprecedented precision. These measurements will impose a fundamental "integral constraint" on models of galaxy formation and the injection of feedback energy over cosmic time.

CMB in a box: Causal structure and the Fourier-Bessel expansion

International Nuclear Information System (INIS)

Abramo, L. Raul; Reimberg, Paulo H.; Xavier, Henrique S.

2010-01-01

This paper makes two points. First, we show that the line-of-sight solution to cosmic microwave anisotropies in Fourier space, even though formally defined for arbitrarily large wavelengths, leads to position-space solutions which only depend on the sources of anisotropies inside the past light cone of the observer. This foretold manifestation of causality in position (real) space happens order by order in a series expansion in powers of the visibility γ=e -μ , where μ is the optical depth to Thomson scattering. We show that the contributions of order γ N to the cosmic microwave background (CMB) anisotropies are regulated by spacetime window functions which have support only inside the past light cone of the point of observation. Second, we show that the Fourier-Bessel expansion of the physical fields (including the temperature and polarization momenta) is an alternative to the usual Fourier basis as a framework to compute the anisotropies. The viability of the Fourier-Bessel series for treating the CMB is a consequence of the fact that the visibility function becomes exponentially small at redshifts z>>10 3 , effectively cutting off the past light cone and introducing a finite radius inside which initial conditions can affect physical observables measured at our position x-vector=0 and time t 0 . Hence, for each multipole l there is a discrete tower of momenta k il (not a continuum) which can affect physical observables, with the smallest momenta being k 1l ∼l. The Fourier-Bessel modes take into account precisely the information from the sources of anisotropies that propagates from the initial value surface to the point of observation - no more, no less. We also show that the physical observables (the temperature and polarization maps), and hence the angular power spectra, are unaffected by that choice of basis. This implies that the Fourier-Bessel expansion is the optimal scheme with which one can compute CMB anisotropies.

Combined sequencing of mRNA and DNA from human embryonic stem cells

Directory of Open Access Journals (Sweden)

Florian Mertes

2016-06-01

Full Text Available Combined transcriptome and whole genome sequencing of the same ultra-low input sample down to single cells is a rapidly evolving approach for the analysis of rare cells. Besides stem cells, rare cells originating from tissues like tumor or biopsies, circulating tumor cells and cells from early embryonic development are under investigation. Herein we describe a universal method applicable for the analysis of minute amounts of sample material (150 to 200 cells derived from sub-colony structures from human embryonic stem cells. The protocol comprises the combined isolation and separate amplification of poly(A mRNA and whole genome DNA followed by next generation sequencing. Here we present a detailed description of the method developed and an overview of the results obtained for RNA and whole genome sequencing of human embryonic stem cells, sequencing data is available in the Gene Expression Omnibus (GEO database under accession number GSE69471.

Fermat Potentials of Embedded Lensing, the Integrated Sachs-Wolfe Effect, and Weak-Lensing of CMB by Cosmic Voids

Science.gov (United States)

Chen, Bin; Kantowski, R.; Dai, X.

2014-01-01

We have developed an accurate gravitational lens theory for an inhomogeneity embedded in an otherwise homogeneous universe, which to the lowest order is applicable to any mass distribution. We derive the Fermat potential for a spherically symmetric lens embedded in a FLRW cosmology and use it to investigate the late-time integrated Sachs-Wolfe effect (ISW) caused by individual large scale inhomogeneities, in particular, cosmic voids. We present a simple analytical expression for the CMB temperature fluctuation across such a lens as the derivative of the lens Fermat potential. Our formalism is applicable to both linear and nonlinear density evolution scenarios, to arbitrarily large density contrasts, and to all open and closed background cosmologies. Our results are particularly useful for modeling ISW effects extracted through stacking large numbers of cosmic voids and clusters (that is, the aperture photometry method). For structures co-expanding with the background cosmology, i.e., for time-independent density contrasts, we find that the gravitational lensing time delay alone can produce fluctuations of the order of seen in recent observations by WMAP and Planck. We revisit the possibility of explaining the non-Gaussian cold spot on the south hemisphere via the Rees-Sciama effect of a large cosmic void using constraints obtained from the most recent void catalogs and our new void-lensing formalism, and compare it with other explanations such as a collapsing cosmic texture. We also study the remapping of primordial CMB anisotropies, the weak-lensing shear, and magnification caused by void lensing.

Confronting hybrid inflation in supergravity with CMB data

International Nuclear Information System (INIS)

Jeannerot, Rachel; Postma, Marieke

2005-01-01

F-term GUT inflation coupled to N = 1 supergravity is confronted with CMB data. Corrections to the string mass-per-unit-length away from the Bogomolny limit are taken into account. We find that a superpotential coupling 10 -7 /N∼ -2 /N, with N the dimension of the Higgs-representation, is still compatible with the data. The parameter space is enlarged in warm inflation, as well as in the curvaton and inhomogeneous reheat scenario. F-strings formed at the end of P-term inflation are also considered. Because these strings satisfy the Bogomolny bound the bounds are stronger: the gauge coupling is constrained to the range 10 -7 -4

Planck CMB Anomalies: Astrophysical and Cosmological Secondary Effects and the Curse of Masking

Science.gov (United States)

Rassat, Anais

2016-07-01

Large-scale anomalies have been reported in CMB data with both WMAP and Planck data. These could be due to foreground residuals and or systematic effects, though their confirmation with Planck data suggests they are not due to a problem in the WMAP or Planck pipelines. If these anomalies are in fact primordial, then understanding their origin is fundamental to either validate the standard model of cosmology or to explore new physics. We investigate three other possible issues: 1) the trade-off between minimising systematics due to foreground contamination (with a conservative mask) and minimising systematics due to masking, 2) astrophysical secondary effects (the kinetic Doppler quadrupole and kinetic Sunyaev-Zel'dovich effect), and 3) secondary cosmological signals (the integrated Sachs-Wolfe effect). We address the masking issue by considering new procedures that use both WMAP and Planck to produce higher quality full-sky maps using the sparsity methodology (LGMCA maps). We show the impact of masking is dominant over that of residual foregrounds, and the LGMCA full-sky maps can be used without further processing to study anomalies. We consider four official Planck PR1 and two LGMCA CMB maps. Analysis of the observed CMB maps shows that only the low quadrupole and quadrupole-octopole alignment seem significant, but that the planar octopole, Axis of Evil, mirror parity and cold spot are not significant in nearly all maps considered. After subtraction of astrophysical and cosmological secondary effects, only the low quadrupole may still be considered anomalous, meaning the significance of only one anomaly is affected by secondary effect subtraction out of six anomalies considered. In the spirit of reproducible research all reconstructed maps and codes are available online.

Robust forecasts on fundamental physics from the foreground-obscured, gravitationally-lensed CMB polarization

Energy Technology Data Exchange (ETDEWEB)

Errard, Josquin [Sorbonne Universités, Institut Lagrange de Paris (ILP), 98 bis Boulevard Arago, 75014 Paris (France); Feeney, Stephen M.; Jaffe, Andrew H. [Department of Physics, Blackett Laboratory, Imperial College London, Prince Consort Road, London SW7 2AZ (United Kingdom); Peiris, Hiranya V., E-mail: josquin.errard@lpnhe.in2p3.fr, E-mail: s.feeney@imperial.ac.uk, E-mail: h.peiris@ucl.ac.uk, E-mail: a.jaffe@imperial.ac.uk [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

2016-03-01

Recent results from the BICEP, Keck Array and Planck Collaborations demonstrate that Galactic foregrounds are an unavoidable obstacle in the search for evidence of inflationary gravitational waves in the cosmic microwave background (CMB) polarization. Beyond the foregrounds, the effect of lensing by intervening large-scale structure further obscures all but the strongest inflationary signals permitted by current data. With a plethora of ongoing and upcoming experiments aiming to measure these signatures, careful and self-consistent consideration of experiments' foreground- and lensing-removal capabilities is critical in obtaining credible forecasts of their performance. We investigate the capabilities of instruments such as Advanced ACTPol, BICEP3 and Keck Array, CLASS, EBEX10K, PIPER, Simons Array, SPT-3G and SPIDER, and projects as COrE+, LiteBIRD-ext, PIXIE and Stage IV, to clean contamination due to polarized synchrotron and dust from raw multi-frequency data, and remove lensing from the resulting co-added CMB maps (either using iterative CMB-only techniques or through cross-correlation with external data). Incorporating these effects, we present forecasts for the constraining power of these experiments in terms of inflationary physics, the neutrino sector, and dark energy parameters. Made publicly available through an online interface, this tool enables the next generation of CMB experiments to foreground-proof their designs, optimize their frequency coverage to maximize scientific output, and determine where cross-experimental collaboration would be most beneficial. We find that analyzing data from ground, balloon and space instruments in complementary combinations can significantly improve component separation performance, delensing, and cosmological constraints over individual datasets. In particular, we find that a combination of post-2020 ground- and space-based experiments could achieve constraints such as σ(r)∼1.3×10{sup −4}, σ(n{sub t})∼0

New ALMA and Fermi /LAT Observations of the Large-scale Jet of PKS 0637−752 Strengthen the Case Against the IC/CMB Model

Energy Technology Data Exchange (ETDEWEB)

Meyer, Eileen T.; Breiding, Peter; Georganopoulos, Markos [University of Maryland, Baltimore County, 1000 Hilltop Circle, Baltimore, MD 21250 (United States); Oteo, Iván; Ivison, R. J. [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Zwaan, Martin A.; Laing, Robert [European Southern Observatory, Karl-Schwarzschild-Str. 2, D-85748 Garching-bei-München (Germany); Godfrey, Leith, E-mail: meyer@umbc.edu [ASTRON, the Netherlands Institute for Radio Astronomy, Postbus 2, 7990 AA Dwingeloo (Netherlands)

2017-02-01

The Chandra X-ray observatory has discovered several dozen anomalously X-ray-bright jets associated with powerful quasars. A popular explanation for the X-ray flux from the knots in these jets is that relativistic synchrotron-emitting electrons inverse-Compton scatter cosmic microwave background (CMB) photons to X-ray energies (the IC/CMB model). This model predicts a high gamma-ray flux that should be detectable by the Fermi /Large Area Telescope (LAT) for many sources. GeV-band upper limits from Fermi /LAT for the well-known anomalous X-ray jet in PKS 0637−752 were previously shown in Meyer et al. to violate the predictions of the IC/CMB model. Previously, measurements of the jet synchrotron spectrum, important for accurately predicting the gamma-ray flux level, were lacking between radio and infrared wavelengths. Here, we present new Atacama Large Millimeter/submillimeter Array (ALMA) observations of the large-scale jet at 100, 233, and 319 GHz, which further constrain the synchrotron spectrum, supporting the previously published empirical model. We also present updated limits from the Fermi /LAT using the new “Pass 8” calibration and approximately 30% more time on source. With these deeper limits, we rule out the IC/CMB model at the 8.7 σ level. Finally, we demonstrate that complete knowledge of the synchrotron SED is critical in evaluating the IC/CMB model.

Primordial Magnetic Field Effects on the CMB and Large-Scale Structure

Directory of Open Access Journals (Sweden)

Dai G. Yamazaki

2010-01-01

Full Text Available Magnetic fields are everywhere in nature, and they play an important role in every astronomical environment which involves the formation of plasma and currents. It is natural therefore to suppose that magnetic fields could be present in the turbulent high-temperature environment of the big bang. Such a primordial magnetic field (PMF would be expected to manifest itself in the cosmic microwave background (CMB temperature and polarization anisotropies, and also in the formation of large-scale structure. In this paper, we summarize the theoretical framework which we have developed to calculate the PMF power spectrum to high precision. Using this formulation, we summarize calculations of the effects of a PMF which take accurate quantitative account of the time evolution of the cutoff scale. We review the constructed numerical program, which is without approximation, and an improvement over the approach used in a number of previous works for studying the effect of the PMF on the cosmological perturbations. We demonstrate how the PMF is an important cosmological physical process on small scales. We also summarize the current constraints on the PMF amplitude Bλ and the power spectral index nB which have been deduced from the available CMB observational data by using our computational framework.

Thermal history of the universe after inflation

Energy Technology Data Exchange (ETDEWEB)

Watson, Scott, E-mail: gswatson@syr.edu [Department of Physics, Syracuse University, Syracuse, NY 13244 (United States)

2016-06-21

When did the universe thermalize? In this talk I review the status of this issue and its importance in establishing the expected properties of dark matter, the growth of large-scale structure, and the viability of inflation models when confronted with CMB observations. I also present a novel approach to tackling the theoretical challenges surrounding inflationary (p)reheating, which seeks to extend past work on the Effective Field Theory of Inflation to the time of reheating.

Study of the concordance of a matter-antimatter symmetric Dirac-Milne Universe

International Nuclear Information System (INIS)

Benoit-Levy, A.

2009-09-01

This thesis is devoted to the study of the Dirac-Milne Universe, a cosmological model in which matter and antimatter are present in equal quantities and where antimatter, as suggested by general relativity through the properties of the Kerr-Newman solutions, is supposed to have a negative active gravitational mass. Supposing such hypothesis removes the necessity to invoke inflation, Dark Energy and Dark matter as mandatory components. Matter (with positive mass) and antimatter (with negative mass) being present in equal quantities, the scale factor evolves linearly with time. After a short summary of basic properties of standard cosmology, some consequences of this linear evolution are studied. The full study of primordial nucleosynthesis within the framework of the Dirac-Milne universe reveals that deuterium can be produced by residual annihilations between matter and antimatter shortly before recombination. Even though Dirac-Milne universe does not present any recent acceleration of the expansion, it is shown that this model is in good agreement with the cosmological test of type Ia supernovae. It is also shown that the position of the acoustic scale of the Cosmic Microwave Background (CMB) naturally appears at the degree scale. The full study of the CMB spectrum and the coherence of the notion of negative mass remain to be investigated, but this work exhibits a original model that could potentially give an alternative description of our Universe. (author)

Discovery of Uniformly Expanding Universe

Directory of Open Access Journals (Sweden)

Cahill R. T.

2012-01-01

Full Text Available Saul Perlmutter and the Brian Schmidt – Adam Riess teams reported that their Friedmann-model GR-based analysis of their supernovae magnitude-redshift data re- vealed a new phenomenon of “dark energy” which, it is claimed, forms 73% of the energy / matter density of the present-epoch universe, and which is linked to the further claim of an accelerating expansion of the universe. In 2011 Perlmutter, Schmidt and Riess received the Nobel Prize in Physics “for the discovery of the accelerating ex- pansion of the Universe through observations of distant supernovae”. Here it is shown that (i a generic model-independent analysis of this data reveals a uniformly expanding universe, (ii their analysis actually used Newtonian gravity, and finally (iii the data, as well as the CMB fluctuation data, does not require “dark energy” nor “dark matter”, but instead reveals the phenomenon of a dynamical space, which is absent from the Friedmann model.

Vertebrate Embryonic Cleavage Pattern Determination.

Science.gov (United States)

Hasley, Andrew; Chavez, Shawn; Danilchik, Michael; Wühr, Martin; Pelegri, Francisco

2017-01-01

The pattern of the earliest cell divisions in a vertebrate embryo lays the groundwork for later developmental events such as gastrulation, organogenesis, and overall body plan establishment. Understanding these early cleavage patterns and the mechanisms that create them is thus crucial for the study of vertebrate development. This chapter describes the early cleavage stages for species representing ray-finned fish, amphibians, birds, reptiles, mammals, and proto-vertebrate ascidians and summarizes current understanding of the mechanisms that govern these patterns. The nearly universal influence of cell shape on orientation and positioning of spindles and cleavage furrows and the mechanisms that mediate this influence are discussed. We discuss in particular models of aster and spindle centering and orientation in large embryonic blastomeres that rely on asymmetric internal pulling forces generated by the cleavage furrow for the previous cell cycle. Also explored are mechanisms that integrate cell division given the limited supply of cellular building blocks in the egg and several-fold changes of cell size during early development, as well as cytoskeletal specializations specific to early blastomeres including processes leading to blastomere cohesion. Finally, we discuss evolutionary conclusions beginning to emerge from the contemporary analysis of the phylogenetic distributions of cleavage patterns. In sum, this chapter seeks to summarize our current understanding of vertebrate early embryonic cleavage patterns and their control and evolution.

Mechanobiology of embryonic limb development.

Science.gov (United States)

Nowlan, Niamh C; Murphy, Paula; Prendergast, Patrick J

2007-04-01

Considerable evidence exists to support the hypothesis that mechanical forces have an essential role in healthy embryonic skeletal development. Clinical observations and experimental data indicate the importance of muscle contractions for limb development. However, the influence of these forces is seldom referred to in biological descriptions of bone development, and perhaps this is due to the fact that the hypothesis that mechanical forces are essential for normal embryonic skeletal development is difficult to test and elaborate experimentally in vivo, particularly in humans. Computational modeling has the potential to address this issue by simulating embryonic growth under a range of loading conditions but the potential of such models has yet to be fully exploited. In this article, we review the literature on mechanobiology of limb development in three main sections: (a) experimental alteration of the mechanical environment, (b) mechanical properties of embryonic tissues, and (c) the use of computational models. Then we analyze the main issues, and suggest how experimental and computational fields could work closer together to enhance our understanding of mechanobiology of the embryonic skeleton.

Is the Cosmic Microwave Background a Shell Around Us? or are the Microwaves Everywhere in the Universe?

Science.gov (United States)

Mather, John

2015-01-01

A: The cosmic microwave background (CMB) radiation fills the universe and travels in all directions. As we see it from here in satellite maps, it is about equally bright in all directions, and thats one of the main reasons we know its cosmic.

Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells.

NARCIS (Netherlands)

Dormeyer, W.; van Hoof, D.; Braam, S.R.; Heck, A.J.R.; Mummery, C.L.; Krijgsveld, J.

2008-01-01

Human embryonic stem cells (hESCs) are of immense interest in regenerative medicine as they can self-renew indefinitely and can give rise to any adult cell type. Human embryonal carcinoma cells (hECCs) are the malignant counterparts of hESCs found in testis tumors. hESCs that have acquired

Real Space Approach to CMB deboosting

CERN Document Server

Yoho, Amanda; Starkman, Glenn D.; Pereira, Thiago S.

2013-01-01

The effect of our Galaxy's motion through the Cosmic Microwave Background rest frame, which aberrates and Doppler shifts incoming photons measured by current CMB experiments, has been shown to produce mode-mixing in the multipole space temperature coefficients. However, multipole space determinations are subject to many difficulties, and a real-space analysis can provide a straightforward alternative. In this work we describe a numerical method for removing Lorentz- boost effects from real-space temperature maps. We show that to deboost a map so that one can accurately extract the temperature power spectrum requires calculating the boost kernel at a finer pixelization than one might naively expect. In idealized cases that allow for easy comparison to analytic results, we have confirmed that there is indeed mode mixing among the spherical harmonic coefficients of the temperature. We find that using a boost kernel calculated at Nside=8192 leads to a 1% bias in the binned boosted power spectrum at l~2000, while ...

SEPHIROT: Scenario for Universe-Creation AUTOMATICALLY from Digits On-Average Euler-Bernoulli-Kummer-Riemann-Newcomb-Poincare-Weyl-Benford-Kac-Raimi-Hill-Antonoff-Siegel ``Digit-Physics'' Logarithm-Law: ``It's a Jack-in-the-Box Universe'': EMET/TRUTH!!!

Science.gov (United States)

Siegel, Edward Carl-Ludwig; Young, Frederic; Wignall, Janis

2013-04-01

SEPHIROT: Siegel[http://fqxi.org/community/forum/topic/1553]: Ten-[0->9]-Digits; Average Log-Law SCALE-Invariance; Utter-Simplicity: ``Complexity'' (vs. ``Complicatedness''); Zipf-law/Hyperbolicity/ Inevitability SCENARIO AUTOMATICALLY CREATES & EVOLVES a UNIVERSE: inflation, a big-bang, bosons(E)->Mellin-(c2)-tranform->fermions(m), hidden-dark-energy(HDE), hidden-dark-matter (HDM), cosmic-microwave-background(CMB), supersymmetry(SUSY), PURPOSELY NO: theories,models,mechanisms,processes, parameters,assumptions,WHATSOEVER: It's a ``Jack-in-the-Box'' Universe!!!: ONLY VIA: Newcomb [Am.J.Math.4(1),39(1881)]QUANTUM-discovery!!!-Benford-Siegel-Antonoff[AMS.Joint-Mtg.(02)-Abs.#973-60-124!!!] inversion to ONLY BEQS with d=0 BEC: ``Digit-Physics''!; Log fixed-point invariance(s): [base=units=SCALE] of digits classic (not classical!) average [CAUSING] log statistical-correlations =log(1+1/d), with physics-crucial d=0 BEC singularity/pole, permits SEPHIROT!!!: ``digits are quanta are bosons because bosons are and always were digits!!!'': Digits = Bosons with d=0 BEC(!!!) & expansion to Zipf-law Hyperbolicity INEVITABILITY CMB!

Multitracer CMB delensing maps from Planck and WISE data

Science.gov (United States)

Yu, Byeonghee; Hill, J. Colin; Sherwin, Blake D.

2017-12-01

Delensing, the removal of the limiting lensing B -mode background, is crucial for the success of future cosmic microwave background (CMB) surveys in constraining inflationary gravitational waves (IGWs). In recent work, delensing with large-scale structure tracers has emerged as a promising method both for improving constraints on IGWs and for testing delensing methods for future use. However, the delensing fractions (i.e., the fraction of the lensing-B mode power removed) achieved by recent efforts have been only 20%-30%. In this work, we provide a detailed characterization of a full-sky, dust-cleaned cosmic infrared background (CIB) map for delensing and construct a further-improved delensing template by adding additional tracers to increase delensing performance. In particular, we build a multitracer delensing template by combining the dust-cleaned Planck CIB map with a reconstructed CMB lensing map from Planck and a galaxy number density map from the Wide-field Infrared Survey Explorer (WISE) satellite. For this combination, we calculate the relevant weightings by fitting smooth templates to measurements of all the cross-spectra and autospectra of these maps. On a large fraction of the sky (fsky=0.43 ), we demonstrate that our maps are capable of providing a delensing factor of 43 ±1 % ; using a more restrictive mask (fsky=0.11 ), the delensing factor reaches 48 ±1 % . For low-noise surveys, our delensing maps, which cover much of the sky, can thus improve constraints on the tensor-to-scalar ratio (r ) by nearly a factor of 2. The delensing tracer maps are made publicly available, and we encourage their use in ongoing and upcoming B -mode surveys.

The X-ray emission mechanism of large scale powerful quasar jets: Fermi rules out IC/CMB for 3C 273.

Directory of Open Access Journals (Sweden)

Georganopoulos Markos

2013-12-01

Full Text Available The process responsible for the Chandra-detected X-ray emission from the large-scale jets of powerful quasars is not clear yet. The two main models are inverse Compton scattering off the cosmic microwave background photons (IC/CMB and synchrotron emission from a population of electrons separate from those producing the radio-IR emission. These two models imply radically different conditions in the large scale jet in terms of jet speed, kinetic power, and maximum energy of the particle acceleration mechanism, with important implications for the impact of the jet on the larger-scale environment. Georganopoulos et al. (2006 proposed a diagnostic based on a fundamental difference between these two models: the production of synchrotron X-rays requires multi-TeV electrons, while the EC/CMB model requires a cutoff in the electron energy distribution below TeV energies. This has significant implications for the γ-ray emission predicted by these two models. Here we present new Fermi observations that put an upper limit on the gamma-ray flux from the large-scale jet of 3C 273 that clearly violates the flux expected from the IC/CMB X-ray interpretation found by extrapolation of the UV to X-ray spectrum of knot A, thus ruling out the IC/CMB interpretation entirely for this source. Further, the upper limit from Fermi puts a limit on the Doppler beaming factor of at least δ <9, assuming equipartition fields, and possibly as low as δ <5 assuming no major deceleration of the jet from knots A through D1.

Searching for cosmic strings in CMB anisotropy maps using wavelets and curvelets

Energy Technology Data Exchange (ETDEWEB)

Hergt, Lukas; Amara, Adam; Kacprzak, Tomasz; Réfrégier, Alexandre [ETH Zurich, Department of Physics, Wolfgang-Pauli-Strasse 27, 8093 Zurich (Switzerland); Brandenberger, Robert, E-mail: hergtl@phys.ethz.ch, E-mail: adam.amara@phys.ethz.ch, E-mail: rhb@physics.mcgill.ca, E-mail: tomasz.kacprzak@phys.ethz.ch, E-mail: alexandre.refregier@phys.ethz.ch [Physics Department, McGill University, Montreal, QC, H3A 2T8 (Canada)

2017-06-01

We use wavelet and curvelet transforms to extract signals of cosmic strings from simulated cosmic microwave background (CMB) temperature anisotropy maps, and to study the limits on the cosmic string tension which various ongoing CMB temperature anisotropy experiments will be able to achieve. We construct sky maps with size and angular resolution corresponding to various experiments. These maps contain the signals of a scaling solution of long string segments with a given string tension G μ, the contribution of the dominant Gaussian primordial cosmological fluctuations, and pixel by pixel white noise with an amplitude corresponding to the instrumental noise of the various experiments. In the case that we include white noise, we find that using curvelets we obtain lower bounds on the string tension than with wavelets. For maps with Planck specification, we obtain bounds comparable to what was obtained by the Planck collaboration [1]. Experiments with better angular resolution such as the South Pole Telescope third generation (SPT-3G) survey will be able to yield stronger limits. For maps with a specification of SPT-3G we find that string signals will be visible down to a string tension of G μ = 1.4 × 10{sup −7}.

Searching for cosmic strings in CMB anisotropy maps using wavelets and curvelets

International Nuclear Information System (INIS)

Hergt, Lukas; Amara, Adam; Kacprzak, Tomasz; Réfrégier, Alexandre; Brandenberger, Robert

2017-01-01

We use wavelet and curvelet transforms to extract signals of cosmic strings from simulated cosmic microwave background (CMB) temperature anisotropy maps, and to study the limits on the cosmic string tension which various ongoing CMB temperature anisotropy experiments will be able to achieve. We construct sky maps with size and angular resolution corresponding to various experiments. These maps contain the signals of a scaling solution of long string segments with a given string tension G μ, the contribution of the dominant Gaussian primordial cosmological fluctuations, and pixel by pixel white noise with an amplitude corresponding to the instrumental noise of the various experiments. In the case that we include white noise, we find that using curvelets we obtain lower bounds on the string tension than with wavelets. For maps with Planck specification, we obtain bounds comparable to what was obtained by the Planck collaboration [1]. Experiments with better angular resolution such as the South Pole Telescope third generation (SPT-3G) survey will be able to yield stronger limits. For maps with a specification of SPT-3G we find that string signals will be visible down to a string tension of G μ = 1.4 × 10 −7 .

How the embryonic chick brain twists

OpenAIRE

Chen, Zi; Guo, Qiaohang; Dai, Eric; Forsch, Nickolas; Taber, Larry A.

2016-01-01

During early development, the tubular embryonic chick brain undergoes a combination of progressive ventral bending and rightward torsion, one of the earliest organ-level left–right asymmetry events in development. Existing evidence suggests that bending is caused by differential growth, but the mechanism for the predominantly rightward torsion of the embryonic brain tube remains poorly understood. Here, we show through a combination of in vitro experiments, a physical model of the embryonic m...

Dark energy and dark matter perturbations in singular universes

International Nuclear Information System (INIS)

Denkiewicz, Tomasz

2015-01-01

We discuss the evolution of density perturbations of dark matter and dark energy in cosmological models which admit future singularities in a finite time. Up to now geometrical tests of the evolution of the universe do not differentiate between singular universes and ΛCDM scenario. We solve perturbation equations using the gauge invariant formalism. The analysis shows that the detailed reconstruction of the evolution of perturbations within singular cosmologies, in the dark sector, can exhibit important differences between the singular universes models and the ΛCDM cosmology. This is encouraging for further examination and gives hope for discriminating between those models with future galaxy weak lensing experiments like the Dark Energy Survey (DES) and Euclid or CMB observations like PRISM and CoRE

Thermal Condensate Structure and Cosmological Energy Density of the Universe

Directory of Open Access Journals (Sweden)

Antonio Capolupo

2016-01-01

Full Text Available The aim of this paper is to study thermal vacuum condensate for scalar and fermion fields. We analyze the thermal states at the temperature of the cosmic microwave background (CMB and we show that the vacuum expectation value of the energy momentum tensor density of photon fields reproduces the energy density and pressure of the CMB. We perform the computations in the formal framework of the Thermo Field Dynamics. We also consider the case of neutrinos and thermal states at the temperature of the neutrino cosmic background. Consistency with the estimated lower bound of the sum of the active neutrino masses is verified. In the boson sector, nontrivial contribution to the energy of the universe is given by particles of masses of the order of 10−4 eV compatible with the ones of the axion-like particles. The fractal self-similar structure of the thermal radiation is also discussed and related to the coherent structure of the thermal vacuum.

On the chaoticity of active-sterile neutrino oscillations in the early universe

DEFF Research Database (Denmark)

Braad, Poul-Erik; Hannestad, Steen

2000-01-01

We have investigated the evolution of the neutrino asymmetry in active-sterile neutrino oscillations in the early universe. We find that there are large regions of parameter space where the asymmetry is extremely sensitive to variations in the initial asymmetry as well as the external parameters ...... asymmetry is stochastic. We discuss the implications of our findings for Big Bang nucleosynthesis (BBN) and the cosmic microwave background (CMB)....

How CMB and large-scale structure constrain chameleon interacting dark energy

International Nuclear Information System (INIS)

Boriero, Daniel; Das, Subinoy; Wong, Yvonne Y.Y.

2015-01-01

We explore a chameleon type of interacting dark matter-dark energy scenario in which a scalar field adiabatically traces the minimum of an effective potential sourced by the dark matter density. We discuss extensively the effect of this coupling on cosmological observables, especially the parameter degeneracies expected to arise between the model parameters and other cosmological parameters, and then test the model against observations of the cosmic microwave background (CMB) anisotropies and other cosmological probes. We find that the chameleon parameters α and β, which determine respectively the slope of the scalar field potential and the dark matter-dark energy coupling strength, can be constrained to α < 0.17 and β < 0.19 using CMB data and measurements of baryon acoustic oscillations. The latter parameter in particular is constrained only by the late Integrated Sachs-Wolfe effect. Adding measurements of the local Hubble expansion rate H 0 tightens the bound on α by a factor of two, although this apparent improvement is arguably an artefact of the tension between the local measurement and the H 0 value inferred from Planck data in the minimal ΛCDM model. The same argument also precludes chameleon models from mimicking a dark radiation component, despite a passing similarity between the two scenarios in that they both delay the epoch of matter-radiation equality. Based on the derived parameter constraints, we discuss possible signatures of the model for ongoing and future large-scale structure surveys

Local properties of the large-scale peaks of the CMB temperature

Energy Technology Data Exchange (ETDEWEB)

Marcos-Caballero, A.; Martínez-González, E.; Vielva, P., E-mail: marcos@ifca.unican.es, E-mail: martinez@ifca.unican.es, E-mail: vielva@ifca.unican.es [Instituto de Física de Cantabria, CSIC-Universidad de Cantabria, Avda. de los Castros s/n, 39005 Santander (Spain)

2017-05-01

In the present work, we study the largest structures of the CMB temperature measured by Planck in terms of the most prominent peaks on the sky, which, in particular, are located in the southern galactic hemisphere. Besides these large-scale features, the well-known Cold Spot anomaly is included in the analysis. All these peaks would contribute significantly to some of the CMB large-scale anomalies, as the parity and hemispherical asymmetries, the dipole modulation, the alignment between the quadrupole and the octopole, or in the case of the Cold Spot, to the non-Gaussianity of the field. The analysis of the peaks is performed by using their multipolar profiles, which characterize the local shape of the peaks in terms of the discrete Fourier transform of the azimuthal angle. In order to quantify the local anisotropy of the peaks, the distribution of the phases of the multipolar profiles is studied by using the Rayleigh random walk methodology. Finally, a direct analysis of the 2-dimensional field around the peaks is performed in order to take into account the effect of the galactic mask. The results of the analysis conclude that, once the peak amplitude and its first and second order derivatives at the centre are conditioned, the rest of the field is compatible with the standard model. In particular, it is observed that the Cold Spot anomaly is caused by the large value of curvature at the centre.

How CMB and large-scale structure constrain chameleon interacting dark energy

Energy Technology Data Exchange (ETDEWEB)

Boriero, Daniel [Fakultät für Physik, Universität Bielefeld, Universitätstr. 25, Bielefeld (Germany); Das, Subinoy [Indian Institute of Astrophisics, Bangalore, 560034 (India); Wong, Yvonne Y.Y., E-mail: boriero@physik.uni-bielefeld.de, E-mail: subinoy@iiap.res.in, E-mail: yvonne.y.wong@unsw.edu.au [School of Physics, The University of New South Wales, Sydney NSW 2052 (Australia)

2015-07-01

We explore a chameleon type of interacting dark matter-dark energy scenario in which a scalar field adiabatically traces the minimum of an effective potential sourced by the dark matter density. We discuss extensively the effect of this coupling on cosmological observables, especially the parameter degeneracies expected to arise between the model parameters and other cosmological parameters, and then test the model against observations of the cosmic microwave background (CMB) anisotropies and other cosmological probes. We find that the chameleon parameters α and β, which determine respectively the slope of the scalar field potential and the dark matter-dark energy coupling strength, can be constrained to α < 0.17 and β < 0.19 using CMB data and measurements of baryon acoustic oscillations. The latter parameter in particular is constrained only by the late Integrated Sachs-Wolfe effect. Adding measurements of the local Hubble expansion rate H{sub 0} tightens the bound on α by a factor of two, although this apparent improvement is arguably an artefact of the tension between the local measurement and the H{sub 0} value inferred from Planck data in the minimal ΛCDM model. The same argument also precludes chameleon models from mimicking a dark radiation component, despite a passing similarity between the two scenarios in that they both delay the epoch of matter-radiation equality. Based on the derived parameter constraints, we discuss possible signatures of the model for ongoing and future large-scale structure surveys.

Testing chirality of primordial gravitational waves with Planck and future CMB data: no hope from angular power spectra

Energy Technology Data Exchange (ETDEWEB)

Gerbino, Martina [The Oskar Klein Centre for Cosmoparticle Physics, Department of Physics, Stockholm University, AlbaNova, SE-106 91 Stockholm (Sweden); Gruppuso, Alessandro [INAF, Istituto di Astrofisica Spaziale e Fisica Cosmica di Bologna, via P. Gobetti 101, I-40129 Bologna (Italy); Natoli, Paolo [Dipartimento di Fisica e Scienze della Terra and INFN, Università degli Studi di Ferrara, Via Saragat 1, I-44100 Ferrara (Italy); Shiraishi, Maresuke [Kavli Institute for the Physics and Mathematics of the Universe (Kavli IPMU, WPI), UTIAS, The University of Tokyo, Chiba, 277-8583 (Japan); Melchiorri, Alessandro, E-mail: martina.gerbino@fysik.su.se, E-mail: gruppuso@iasfbo.inaf.it, E-mail: paolo.natoli@gmail.com, E-mail: maresuke.shiraishi@ipmu.jp, E-mail: alessandro.melchiorri@roma1.infn.it [Physics Department and INFN, Università di Roma ' La Sapienza' , P.le Aldo Moro 2, 00185, Rome (Italy)

2016-07-01

We use the 2015 Planck likelihood in combination with the Bicep2/Keck likelihood (BKP and BK14) to constrain the chirality, χ, of primordial gravitational waves in a scale-invariant scenario. In this framework, the parameter χ enters theory always coupled to the tensor-to-scalar ratio, r , e.g. in combination of the form χ ⋅ r . Thus, the capability to detect χ critically depends on the value of r . We find that with present data sets χ is de facto unconstrained. We also provide forecasts for χ from future CMB experiments, including COrE+, exploring several fiducial values of r . We find that the current limit on r is tight enough to disfavor a neat detection of χ. For example, in the unlikely case in which r ∼0.1(0.05), the maximal chirality case, i.e. χ = ±1, could be detected with a significance of ∼2.5(1.5)σ at best. We conclude that the two-point statistics at the basis of CMB likelihood functions is currently unable to constrain chirality and may only provide weak limits on χ in the most optimistic scenarios. Hence, it is crucial to investigate the use of other observables, e.g. provided by higher order statistics, to constrain these kinds of parity violating theories with the CMB.

Quantum Gravity, Information Theory and the CMB

Science.gov (United States)

Kempf, Achim

2018-04-01

We review connections between the metric of spacetime and the quantum fluctuations of fields. We start with the finding that the spacetime metric can be expressed entirely in terms of the 2-point correlator of the fluctuations of quantum fields. We then discuss the open question whether the knowledge of only the spectra of the quantum fluctuations of fields also suffices to determine the spacetime metric. This question is of interest because spectra are geometric invariants and their quantization would, therefore, have the benefit of not requiring the modding out of diffeomorphisms. Further, we discuss the fact that spacetime at the Planck scale need not necessarily be either discrete or continuous. Instead, results from information theory show that spacetime may be simultaneously discrete and continuous in the same way that information can. Finally, we review the recent finding that a covariant natural ultraviolet cutoff at the Planck scale implies a signature in the cosmic microwave background (CMB) that may become observable.

Sensitivity of molecular marker-based CMB models to biomass burning source profiles

Science.gov (United States)

Sheesley, Rebecca J.; Schauer, James J.; Zheng, Mei; Wang, Bo

To assess the contribution of sources to fine particulate organic carbon (OC) at four sites in North Carolina, USA, a molecular marker chemical mass balance model (MM-CMB) was used to quantify seasonal contributions for 2 years. The biomass burning contribution at these sites was found to be 30-50% of the annual OC concentration. In order to provide a better understanding of the uncertainty in MM-CMB model results, a biomass burning profile sensitivity test was performed on the 18 seasonal composites. The results using reconstructed emission profiles based on published profiles compared well, while model results using a single source test profile resulted in biomass burning contributions that were more variable. The biomass burning contribution calculated using an average regional profile of fireplace emissions from five southeastern tree species also compared well with an average profile of open burning of pine-dominated forest from Georgia. The standard deviation of the results using different source profiles was a little over 30% of the annual average biomass contributions. Because the biomass burning contribution accounted for 30-50% of the OC at these sites, the choice of profile also impacted the motor vehicle source attribution due to the common emission of elemental carbon and polycyclic aromatic hydrocarbons. The total mobile organic carbon contribution was less effected by the biomass burning profile than the relative contributions from gasoline and diesel engines.

Multichroic Antenna-Coupled Bolometers for CMB Polarization and Sub-mm Observations

Science.gov (United States)

Lee, Adrian

We propose to develop planar antenna-coupled superconducting bolometer arrays for observations at sub-millimeter to millimeter wavelengths. Our pixel architecture features a dual-polarization log-periodic antenna with a 4:1-bandwidth ratio, followed by a filter bank that divides the total bandwidth into several broad photometric bands. The advantages of this approach, compared with those using conventional single-color pixels, include a combination of greatly reduced focal-plane mass, higher array sensitivity, and a larger number of spectral bands. These advantages have the potential to greatly reduce the cost and/or increase the performance of NASA missions in the sub-millimeter to millimeter bands. For CMB polarization measurements, a wide frequency range of roughly 30 to 300 GHz is required to subtract galactic foregrounds. The multichroic architecture we propose enables a relatively low-cost 30-cm aperture space mission to have sufficient sensitivity to probe below the tensor-to-scalar ratio r = 0.01. For a larger aperture mission, such as the EPIC-IM concept, the proposed technology could reduce the focal-plane mass by a factor of 2-3, with great savings in required cryocooler performance and therefore cost. We have demonstrated the lens-coupled antenna concept in the POLARBEAR ground-based CMB polarization experiment now operating in Chile. That experiment uses a single-band planar antenna and produces excellent beam properties and optical efficiency. In the laboratory, we have measured two octaves of total bandwidth in the log-periodic sinuous antenna. We have built filter banks of 2, 3, and 7 bands with 4, 6, and 14 bolometers per pixel for two linear polarizations. Building on these accomplishments, the deliverables for the proposed work include: *Two pixel types that together cover the range from 30 to 300 GHz. The low-frequency pixel will have bands centered at 35, 50, and 80 GHz and the high frequency pixel will have bands centered at 120, 180, and 270

Forecasts for CMB μ and i-type spectral distortion constraints on the primordial power spectrum on scales 8∼4 Mpc−1 with the future Pixie-like experiments

International Nuclear Information System (INIS)

Khatri, Rishi; Sunyaev, Rashid A.

2013-01-01

Silk damping at redshifts 1.5 × 10 4 ∼ 6 erases CMB anisotropies on scales corresponding to the comoving wavenumbers 8∼ 4 Mpc −1 (10 5 ∼ 8 ). This dissipated energy is gained by the CMB monopole, creating distortions from a blackbody in the CMB spectrum of the μ-type and the i-type. We study, using Fisher matrices, the constraints we can get from measurements of these spectral distortions on the primordial power spectrum from future experiments such as Pixie, and how these constraints change as we change the frequency resolution and the sensitivity of the experiment. We show that the additional information in the shape of the i-type distortions, in combination with the μ-type distortions, allows us to break the degeneracy between the amplitude and the spectral index of the power spectrum on these scales and leads to much tighter constraints. We quantify the information contained in both the μ-type distortions and the i-type distortions taking into account the partial degeneracy with the y-type distortions and the temperature of the blackbody part of the CMB. We also calculate the constraints possible on the primordial power spectrum when the spectral distortion information is combined with the CMB anisotropies measured by the WMAP, SPT, ACT and Planck experiments

Emission-angle and polarization-rotation effects in the lensed CMB

Energy Technology Data Exchange (ETDEWEB)

Lewis, Antony [Department of Physics and Astronomy, University of Sussex, Brighton BN1 9QH (United Kingdom); Hall, Alex [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh, EH9 3HJ (United Kingdom); Challinor, Anthony, E-mail: antony@cosmologist.info, E-mail: ahall@roe.ac.uk, E-mail: a.d.challinor@ast.cam.ac.uk [Institute of Astronomy and Kavli Institute for Cosmology, Madingley Road, Cambridge, CB3 0HA (United Kingdom)

2017-08-01

Lensing of the CMB is an important effect, and is usually modelled by remapping the unlensed CMB fields by a lensing deflection. However the lensing deflections also change the photon path so that the emission angle is no longer orthogonal to the background last-scattering surface. We give the first calculation of the emission-angle corrections to the standard lensing approximation from dipole (Doppler) sources for temperature and quadrupole sources for temperature and polarization. We show that while the corrections are negligible for the temperature and E-mode polarization, additional large-scale B-modes are produced with a white spectrum that dominates those from post-Born field rotation (curl lensing). On large scales about one percent of the total lensing-induced B-mode amplitude is expected to be due to this effect. However, the photon emission angle does remain orthogonal to the perturbed last-scattering surface due to time delay, and half of the large-scale emission-angle B modes cancel with B modes from time delay to give a total contribution of about half a percent. While not important for planned observations, the signal could ultimately limit the ability of delensing to reveal low amplitudes of primordial gravitational waves. We also derive the rotation of polarization due to multiple deflections between emission and observation. The rotation angle is of quadratic order in the deflection angle, and hence negligibly small: polarization typically rotates by less than an arcsecond, orders of magnitude less than a small-scale image rotates due to post-Born field rotation (which is quadratic in the shear). The field-rotation B modes dominate the other effects on small scales.

Universal constraints on axions from inflation

DEFF Research Database (Denmark)

Ferreira, R. Z.; Sloth, M. S.

2014-01-01

-roll evolution of the curvature perturbation on super horizon scales which should be taken into account. We also comment on implications for inflationary models where axions play an important role as, for example, models of natural inflation where more than one axion are included and models where the curvaton...... that the generation of curvature perturbation at horizon crossing due to the axial coupling has a universal form and remains unmodified in terms of the xi parameter even if the axion, sigma, is not identified with the inflaton. As a consequence, it does not appear to be possible to generate CMB tensor perturbations...

CMB B-mode auto-bispectrum produced by primordial gravitational waves

Science.gov (United States)

Tahara, Hiroaki W. H.; Yokoyama, Jun'ichi

2018-01-01

Gravitational waves from inflation induce polarization patterns in the cosmic microwave background (CMB). It is known that there are only two types of non-Gaussianities of the gravitational waves in the most general covariant scalar field theory having second-order field equations, namely, generalized G-inflation. One originates from the inherent non-Gaussianity in general relativity, and the other from a derivative coupling between the Einstein tensor and the scalar field. We calculate polarization bispectra induced by these non-Gaussianities by transforming them into separable forms by virtue of the Laplace transformation. It is shown that future experiments can constrain the new one but cannot detect the general relativistic one.

Low-l CMB power loss in string inflation

Energy Technology Data Exchange (ETDEWEB)

Pedro, Francisco G.; Westphal, Alexander

2013-09-15

The lack of power on large scales (l CMB 2-point function power at low l, finding that the potential derived from string loops is not steep enough for this purpose. We introduce a steeper contribution to the potential, that dominates away from the inflationary region, and show that if properly tuned it can indeed lead to a spectrum with lack of power at large scales.

The CMB neutrino mass/vacuum energy degeneracy: a simple derivation of the degeneracy slopes

Science.gov (United States)

Sutherland, Will

2018-06-01

It is well known that estimating cosmological parameters from cosmic microwave background (CMB) data alone results in a significant degeneracy between the total neutrino mass and several other cosmological parameters, especially the Hubble constant H0 and the matter density parameter Ωm. Adding low-redshift measurements such as baryon acoustic oscillations (BAOs) breaks this degeneracy and greatly improves the constraints on neutrino mass. The sensitivity is surprisingly high, for example, adding the ˜1 percent measurement of the BAO ratio rs/DV from the BOSS survey leads to a limit Σ mν matter ratio (xν ≡ ων/ωcb) and the shifts in other cosmological parameters. The resulting multipliers are substantially larger than 1: conserving the CMB sound horizon angle requires parameter shifts δln H0 ≈ -2 δxν, δln Ωm ≈ +5 δxν, δln ωΛ ≈ -6.2 δxν, and most notably δωΛ ≈ -14 δων. These multipliers give an intuitive derivation of the degeneracy direction, which agrees well with the numerical likelihood results from the Planck team.

Nodal signals mediate interactions between the extra-embryonic and embryonic tissues in zebrafish

OpenAIRE

Xiang, Fan; Hagos, Engda G.; Xu, Bo; Sias, Christina; Kawakami, Koichi; Burdine, Rebecca D.; Dougan, Scott T.

2007-01-01

In many vertebrates, extra-embryonic tissues are important signaling centers that induce and pattern the germ layers. In teleosts, the mechanism by which the extra-embryonic yolk syncytial layer (YSL) patterns the embryo is not understood. Although the Nodal-related protein Squint is expressed in the YSL, its role in this tissue is not known. We generated a series of stable transgenic lines with GFP under the control of squint genomic sequences. In all species, nodal-related genes induce thei...

Non-Gaussianity as a Probe of the Physics of the Primordial Universe and the Astrophysics of the Low Redshift Universe

CERN Document Server

Komatsu, E; Afshordi, N; Bartolo, N; Baumann, D; Bond, J R; Buchbinder, E I; Byrnes, C T; Chen, X; Chung, D J H; Cooray, A; Creminelli, P; Dalal, N; Dore, O; Easther, R; Frolov, A V; Gorski, K M; Jackson, M G; Khoury, J; Kinney, W H; Kofman, L; Koyama, K; Leblond, L; Lehners, J L; Lidsey, J E; Liguori, M; Lim, E A; Linde, A; Lyth, D H; Maldacena, J; Matarrese, S; McAllister, L; McDonald, P; Mukohyama, S; Ovrut, B; Peiris, H V; Rath, C; Riotto, A; Rodriguez, Y; Sasaki, M; Scoccimarro, R; Seery, D; Sefusatti, E; Seljak, U; Senatore, L; Shandera, S; Shellard, E P S; Silverstein, E; Slosar, A; Smith, K M; Starobinsky, A A; Steinhardt, P J; Takahashi, F; Tegmark, M; Tolley, A J; Verde, L; Wandelt, B D; Wands, D; Weinberg, S; Wyman, M; Yadav, A P S; Zaldarriaga, M

2009-01-01

A new and powerful probe of the origin and evolution of structures in the Universe has emerged and been actively developed over the last decade. In the coming decade, non-Gaussianity, i.e., the study of non-Gaussian contributions to the correlations of cosmological fluctuations, will become an important probe of both the early and the late Universe. Specifically, it will play a leading role in furthering our understanding of two fundamental aspects of cosmology and astrophysics: (i) the physics of the very early universe that created the primordial seeds for large-scale structures, and (ii) the subsequent growth of structures via gravitational instability and gas physics at later times. To date, observations of fluctuations in the Cosmic Microwave Background (CMB) and the Large-Scale Structure of the Universe (LSS) have focused largely on the Gaussian contribution as measured by the two-point correlations (or the power spectrum) of density fluctuations. However, an even greater amount of information is contai...

Probing primordial non Gaussianity in the BOOMERanG CMB maps: an analysis based on analytical Minkowski functionals

International Nuclear Information System (INIS)

Migliaccio, M.; Natoli, P.; De Troia, G.; Hikage, C.; Komatsu, E.; Ade, P.A.R.; Bock, J.J.; Bond, J.R.; Borrill, J.; Boscaleri, A.; Contaldi, C.R.; Crill, B.P.; Bernardis, P. de; Gasperis, G. de; Oliveira-Costa, A. de; Di Stefano, G.; Hivon, E.; Kisner, T.S.; Jones, W.C.; Lange, A.E.

2009-01-01

Minkowski functionals are a powerful tool to constrain the Gaussianity of the Cosmic Microwave Background (CMB). In the limit of a weakly non Gaussian field, a perturbative approach can be derived [Hikage C., Komatsu E., and Matsubara T., 2006, ApJ, 653, 11] that is completely based on analytical formulae without requiring computationally intensive, dedicated Monte Carlo non Gaussian simulations of the CMB anisotropy. We apply this machinery to an intensity map derived from the 1998 and 2003 flights of BOOMERanG, analyzed here together for the first time. We set limits on the non-linear coupling parameter f NL as -1020 NL <390 at 95% CL, markedly improving the previous constraints set by [De Troia G. et al., 2007, ApJ, 670, L73] whose analysis was limited to the BOOMERanG 2003 dataset. These limits are the most stringent ever set among suborbital experiments.

Probing primordial non Gaussianity in the BOOMERanG CMB maps: an analysis based on analytical Minkowski functionals

Energy Technology Data Exchange (ETDEWEB)

Migliaccio, M.; Natoli, P.; De Troia, G. [Dipartimento di Fisica, Universita di Roma ' Tor Vergata' , Via della Ricerca Scientifica, 1 I-00133 Roma (Italy); Hikage, C. [School of Physics and Astronomy, Cardiff University, Cardiff, CF24 3AA (United Kingdom); Komatsu, E. [Texas Cosmology Center, University of Texas at Austin, 1 University Station, C1400, Austin, TX 78712 (United States); Ade, P.A.R. [School of Physics and Astronomy, Cardiff University, Cardiff, CF24 3AA (United Kingdom); Bock, J.J. [Jet Propulsion Laboratory, Pasadena, CA (United States); Bond, J.R. [Canadian Institute for Theoretical Astrophysics, University of Toronto, Toronto, Ontario (Canada); Borrill, J. [Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Boscaleri, A. [IFAC-CNR, Firenze (Italy); Contaldi, C.R. [Theoretical Physics Group, Imperial College, London (United Kingdom); Crill, B.P. [Jet Propulsion Laboratory, Pasadena, CA (United States); Bernardis, P. de [Dipartimento di Fisica, Universita La Sapienza, Roma (Italy); Gasperis, G. de [Dipartimento di Fisica, Universita di Roma ' Tor Vergata' , Via della Ricerca Scientifica, 1 I-00133 Roma (Italy); Oliveira-Costa, A. de [Department of Physics, MIT, Cambridge, MA 02139 (United States); Di Stefano, G. [Istituto Nazionale di Geofisica e Vulcanologia, 00143 Rome (Italy); Hivon, E. [Institut d' Astrophysique, Paris (France); Kisner, T.S. [Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA (United States); Jones, W.C. [Department of Physics, Princeton University, Princeton, NJ 0854 (United States); Lange, A.E. [Observational Cosmology, California Institute of Technology, Pasadena, CA (United States)

2009-10-15

Minkowski functionals are a powerful tool to constrain the Gaussianity of the Cosmic Microwave Background (CMB). In the limit of a weakly non Gaussian field, a perturbative approach can be derived [Hikage C., Komatsu E., and Matsubara T., 2006, ApJ, 653, 11] that is completely based on analytical formulae without requiring computationally intensive, dedicated Monte Carlo non Gaussian simulations of the CMB anisotropy. We apply this machinery to an intensity map derived from the 1998 and 2003 flights of BOOMERanG, analyzed here together for the first time. We set limits on the non-linear coupling parameter f{sub NL} as -1020

Altered glucose transport to utero-embryonic unit in relation to delayed embryonic development in the Indian short-nosed fruit bat, Cynopterus sphinx.

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Arnab, Banerjee; Amitabh, Krishna

2011-02-10

The aim of this study was to compare the changes in concentration of glucose and glucose transporters (GLUTs) in the utero-embryonic unit, consisting of decidua, trophoblast and embryo, during delayed and non-delayed periods to understand the possible cause of delayed embryonic development in Cynopterus sphinx. The results showed a significantly decreased concentration of glucose in the utero-embryonic unit due to decline in the expression of insulin receptor (IR) and GLUT 3, 4 and 8 proteins in the utero-embryonic unit during delayed period. The in vitro study showed suppressive effect of insulin on expression of GLUTs 4 and 8 in the utero-embryonic unit and a significant positive correlation between the decreased amount of glucose consumed by the utero-embryonic unit and decreased expression of GLUTs 4 (r=0.99; psphinx. Increased supply of fatty acid to the delayed embryo may be responsible for its survival under low glucose condition but unable to promote embryonic development in C. sphinx. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Constraining dark photon model with dark matter from CMB spectral distortions

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Ki-Young Choi

2017-08-01

Full Text Available Many extensions of Standard Model (SM include a dark sector which can interact with the SM sector via a light mediator. We explore the possibilities to probe such a dark sector by studying the distortion of the CMB spectrum from the blackbody shape due to the elastic scatterings between the dark matter and baryons through a hidden light mediator. We in particular focus on the model where the dark sector gauge boson kinetically mixes with the SM and present the future experimental prospect for a PIXIE-like experiment along with its comparison to the existing bounds from complementary terrestrial experiments.

The 'ventral organs' of Pycnogonida (Arthropoda) are neurogenic niches of late embryonic and post-embryonic nervous system development.

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Brenneis, Georg; Scholtz, Gerhard

2014-01-01

Early neurogenesis in arthropods has been in the focus of numerous studies, its cellular basis, spatio-temporal dynamics and underlying genetic network being by now comparably well characterized for representatives of chelicerates, myriapods, hexapods and crustaceans. By contrast, neurogenesis during late embryonic and/or post-embryonic development has received less attention, especially in myriapods and chelicerates. Here, we apply (i) immunolabeling, (ii) histology and (iii) scanning electron microscopy to study post-embryonic ventral nerve cord development in Pseudopallene sp., a representative of the sea spiders (Pycnogonida), the presumable sister group of the remaining chelicerates. During early post-embryonic development, large neural stem cells give rise to additional ganglion cell material in segmentally paired invaginations in the ventral ectoderm. These ectodermal cell regions - traditionally designated as 'ventral organs' - detach from the surface into the interior and persist as apical cell clusters on the ventral ganglion side. Each cluster is a post-embryonic neurogenic niche that features a tiny central cavity and initially still houses larger neural stem cells. The cluster stays connected to the underlying ganglionic somata cortex via an anterior and a posterior cell stream. Cell proliferation remains restricted to the cluster and streams, and migration of newly produced cells along the streams seems to account for increasing ganglion cell numbers in the cortex. The pycnogonid cluster-stream-systems show striking similarities to the life-long neurogenic system of decapod crustaceans, and due to their close vicinity to glomerulus-like neuropils, we consider their possible involvement in post-embryonic (perhaps even adult) replenishment of olfactory neurons - as in decapods. An instance of a potentially similar post-embryonic/adult neurogenic system in the arthropod outgroup Onychophora is discussed. Additionally, we document two transient posterior

Peculiarities of Embryonic and Post-Embryonic Development of Оesophagostomum dentatum (Nematoda, Strongylidae Larvae Cultured in Vitro

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Yevstafieva V. А.

2017-02-01

Full Text Available Morphometric peculiarities of the development of Оesophagostomum dentatum Rudolphi, 1803 from egg to infective larva were studied under laboratory conditions at various temperatures. The determined optimum temperature for embryonic and post-embryonic development of О. dentatum larvae from domestic pig (Sus scrofa domesticus Linnaeus, 1758 is 22 °С. At this temperature, 81 % of larvae develop to the third stage (L3 on the 10th day. Temperatures of 24 °С and 20 °С are less favorable for the development of the nematode, at those temperatures only 67 and 63 % of larvae, respectively, reached infective stage by the 10th day of cultivation. Embryonic development of О. dentatum eggs is characterized by their lengthening (by 8.87-9.50 %, р < 0.01 and widening (by 6.77-9.35 %, р < 0.05-0.01, and post-embryonic larval development is associated with lengthening (by 4.59-17.33 %, р < 0.01-0.001.

Ethical and regulatory aspects of embryonic stem cell research.

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Jain, Kewal K

2002-12-01

Ethical and regulatory issues concerning embryonic stem (ES) cell research are reviewed here a year after the controversy became a public and political issue in the US. The background of various issues are examined and the current regulations in various countries are reviewed. In the US, the debate is linked with abortion, as well as the status of a fetus as a human being, and is politically driven. Obtaining stem cells from embryonic tissues involves destruction of the embryo, to which objections are raised. Religious beliefs are examined and no serious impediments to ES cell research could be identified. Regulations vary from one country to another and it is unlikely that there will ever be any universally uniform ethical and regulatory standards for ES cell research. Currently, the most liberal and favourable environments for ES cell research are in the UK, Singapore, Sweden, India, Israel and China. Unless the US liberalises ES cell research, it may lose its lead in ES cell research and investments in this area may drift to countries with better environments for research. Suggestions are offered in this review to improve the ethical environment for ES cell research.

Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017

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Fatemeh Akyash

2017-09-01

Full Text Available This report explains briefly the minutes of a 1-day workshop entitled; “human embryonic stem cells (hESCs and good manufacturing practice (GMP” held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

Human embryonic stem cells and good manufacturing practice: Report of a 1- day workshop held at Stem Cell Biology Research Center, Yazd, 27th April 2017.

Science.gov (United States)

Akyash, Fatemeh; Sadeghian-Nodoushan, Fatemeh; Tahajjodi, Somayyeh Sadat; Nikukar, Habib; Farashahi Yazd, Ehsan; Azimzadeh, Mostafa; D Moore, Harry; Aflatoonian, Behrouz

2017-05-01

This report explains briefly the minutes of a 1-day workshop entitled; "human embryonic stem cells (hESCs) and good manufacturing practice (GMP)" held by Stem Cell Biology Research Center based in Yazd Reproductive Sciences Institute at Shahid Sadoughi University of Medical Sciences, Yazd, Iran on 27 th April 2017. In this workshop, in addition to the practical sessions, Prof. Harry D. Moore from Centre for Stem Cell Biology, University of Sheffield, UK presented the challenges and the importance of the biotechnology of clinical-grade human embryonic stem cells from first derivation to robust defined culture for therapeutic applications.

Cross-correlating CMB temperature fluctuations with high-energy γ-ray from Dark-Matter annihilation

International Nuclear Information System (INIS)

Pieri, L.

2013-01-01

In this paper we compute the Integrated Sachs-Wolfe effect due to the presence of dark-matter structures on cosmological scale. We cross-correlate the CMB temperature fluctuations with the extragalactic high-energy γ-ray flux map obtained with FERMI-LAT. We find a null signal consistent with the theory and conclude that the presence of halos and subhalos at galactic and extragalactic scale, if not excluded, will be hardly discoverable.

Constraints on cosmological birefringence energy dependence from CMB polarization data

International Nuclear Information System (INIS)

Gubitosi, G.; Paci, F.

2013-01-01

We study the possibility of constraining the energy dependence of cosmological birefringence by using CMB polarization data. We consider four possible behaviors, characteristic of different theoretical scenarios: energy-independent birefringence motivated by Chern-Simons interactions of the electromagnetic field, linear energy dependence motivated by a 'Weyl' interaction of the electromagnetic field, quadratic energy dependence, motivated by quantum gravity modifications of low-energy electrodynamics, and inverse quadratic dependence, motivated by Faraday rotation generated by primordial magnetic fields. We constrain the parameters associated to each kind of dependence and use our results to give constraints on the models mentioned. We forecast the sensitivity that Planck data will be able to achieve in this respect

The evens and odds of CMB anomalies

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Gruppuso, A.; Kitazawa, N.; Lattanzi, M.; Mandolesi, N.; Natoli, P.; Sagnotti, A.

2018-06-01

The lack of power of large-angle CMB anisotropies is known to increase its statistical significance at higher Galactic latitudes, where a string-inspired pre-inflationary scale Δ can also be detected. Considering the Planck 2015 data, and relying largely on a Bayesian approach, we show that the effect is mostly driven by the even - ℓ harmonic multipoles with ℓ ≲ 20, which appear sizably suppressed in a way that is robust with respect to Galactic masking, along with the corresponding detections of Δ. On the other hand, the first odd - ℓ multipoles are only suppressed at high Galactic latitudes. We investigate this behavior in different sky masks, constraining Δ through even and odd multipoles, and we elaborate on possible implications. We include low- ℓ polarization data which, despite being noise-limited, help in attaining confidence levels of about 3 σ in the detection of Δ. We also show by direct forecasts that a future all-sky E-mode cosmic-variance-limited polarization survey may push the constraining power for Δ beyond 5 σ.

Modeling CMB lensing cross correlations with CLEFT

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Modi, Chirag; White, Martin [Department of Physics, University of California, Berkeley, CA 94720 (United States); Vlah, Zvonimir, E-mail: modichirag@berkeley.edu, E-mail: mwhite@berkeley.edu, E-mail: zvlah@stanford.edu [Stanford Institute for Theoretical Physics and Department of Physics, Stanford University, Stanford, CA 94306 (United States)

2017-08-01

A new generation of surveys will soon map large fractions of sky to ever greater depths and their science goals can be enhanced by exploiting cross correlations between them. In this paper we study cross correlations between the lensing of the CMB and biased tracers of large-scale structure at high z . We motivate the need for more sophisticated bias models for modeling increasingly biased tracers at these redshifts and propose the use of perturbation theories, specifically Convolution Lagrangian Effective Field Theory (CLEFT). Since such signals reside at large scales and redshifts, they can be well described by perturbative approaches. We compare our model with the current approach of using scale independent bias coupled with fitting functions for non-linear matter power spectra, showing that the latter will not be sufficient for upcoming surveys. We illustrate our ideas by estimating σ{sub 8} from the auto- and cross-spectra of mock surveys, finding that CLEFT returns accurate and unbiased results at high z . We discuss uncertainties due to the redshift distribution of the tracers, and several avenues for future development.

Cosmic Topology: Studying The Shape And Size Of Our Universe

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Yzaguirre, Amelia; Hajian, A.

2010-01-01

The question of the size and the shape of our universe is a very old problem that has received considerable attention over the past few years. The simplest cosmological model predicts that the mean density of the universe is very close to the critical density, admitting a local geometry of the universe that is flat. Current results from different cosmological observations confirm this to the percent level accuracy. General Relativity (being a local theory) only determines local geometry, which allows for the possibility of a multiply connected universe with a zero (or small) curvature. To study the global shape, or topology, of the universe, one can use cosmological observations on large scales. In this project we investigate the possibility of a ``small universe'', that is, a compact finite space, by searching for planar symmetries in the CMB anisotropy maps provided by the five-year WMAP observations in two foreground cleaned maps (WMAP ILC map and the Tegmark, et al. (TOH) map ). Our results strongly suggest that the small universe model is not a viable topology for the universe.

Correlated mixture between adiabatic and isocurvature fluctuations and recent CMB observations

International Nuclear Information System (INIS)

Andrade, Ana Paula A.; Wuensche, Carlos Alexandre; Ribeiro, Andre Luis Batista

2005-01-01

This work presents a reduced χ ν 2 test to search for non-Gaussian signals in the cosmic microwave background radiation (CMBR) TT power spectrum of recent CMBR data, Wilkinson Anisotropy Microwave Probe, Arcminute Cosmology Bolometer Array Receiver, and Cosmic Background Imager data sets, assuming a mixed density field including adiabatic and isocurvature fluctuations. We assume a skew positive mixed model with adiabatic inflation perturbations plus additional isocurvature perturbations possibly produced by topological defects. The joint probability distribution used in this context is a weighted combination of Gaussian and non-Gaussian random fields. Results from simulations of CMBR temperature for the mixed field show a distinct signature in CMB power spectrum for very small deviations (∼0.1%) from a pure Gaussian field, and can be used as a direct test for the nature of primordial fluctuations. A reduced χ ν 2 test applied on the most recent CMBR observations reveals that an isocurvature fluctuations field is not ruled out and indeed permits a very good description for a flat geometry Λ-CDM Universe, χ 930 2 ∼1.5, rather than the simple inflationary standard model with χ 930 2 ∼2.3. This result may looks is particular discrepant with the reduced χ 2 of 1.07 obtained with the same model in Spergel et al. [Astrophys. J. 148, 175 (2003)] for temperature only, however, our work is restricted to a region of the parameter space that does not include the best fit model for TT only of Spergel et al.

The periconception maternal cardiovascular risk profile influences human embryonic growth trajectories in IVF/ICSI pregnancies.

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Wijnands, K P J; van Uitert, E M; Roeters van Lennep, J E; Koning, A H J; Mulders, A G M G J; Laven, J S E; Steegers, E A P; Steegers-Theunissen, R P M

2016-06-01

associated with embryonic growth (-0.03√mm; P = 0.291). Stratified by mode of conception, the CV risk score was inversely and significantly associated with embryonic growth (β = -0.04√mm; P = 0.025, adjusted for possible confounders) in the IVF/ICSI group. Compared with the first quartile, embryos in the upper quartile were 10.4% smaller at 6(+0) weeks (4.4 versus 4.9 mm) and 3.1% smaller at 12(+0) weeks (56.5 versus 58.4 mm) of gestation. Although the CV risk score was slightly, but significantly, higher in women conceiving spontaneously compared with those undergoing IVF/ICSI treatment [CV risk score = 2.06 (SD: 1.23) and 1.60 (SD: 1.15), respectively], no association was established with embryonic growth in that particular group. Participants included in the present cohort are women with a singleton ongoing pregnancy without any pre-existing disease and selected from a tertiary hospital. Hence, they represent a selected group of women. Larger and population-based periconception birth cohort studies are recommended to demonstrate external validity. Differences in embryonic growth between pregnancies conceived spontaneously and after IVF/ICSI treatment in relation with CV risk factors substantiate the importance of more investigation into differences in sensitivity of endometrial, endothelial, placental and embryonic tissues. Funded by the Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre, Rotterdam, the Netherlands. The authors declare no conflict of interest. © The Author 2016. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Somatic donor cell type correlates with embryonic, but not extra-embryonic, gene expression in postimplantation cloned embryos.

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Ryutaro Hirasawa

Full Text Available The great majority of embryos generated by somatic cell nuclear transfer (SCNT display defined abnormal phenotypes after implantation, such as an increased likelihood of death and abnormal placentation. To gain better insight into the underlying mechanisms, we analyzed genome-wide gene expression profiles of day 6.5 postimplantation mouse embryos cloned from three different cell types (cumulus cells, neonatal Sertoli cells and fibroblasts. The embryos retrieved from the uteri were separated into embryonic (epiblast and extraembryonic (extraembryonic ectoderm and ectoplacental cone tissues and were subjected to gene microarray analysis. Genotype- and sex-matched embryos produced by in vitro fertilization were used as controls. Principal component analysis revealed that whereas the gene expression patterns in the embryonic tissues varied according to the donor cell type, those in extraembryonic tissues were relatively consistent across all groups. Within each group, the embryonic tissues had more differentially expressed genes (DEGs (>2-fold vs. controls than did the extraembryonic tissues (P<1.0 × 10(-26. In the embryonic tissues, one of the common abnormalities was upregulation of Dlk1, a paternally imprinted gene. This might be a potential cause of the occasional placenta-only conceptuses seen in SCNT-generated mouse embryos (1-5% per embryos transferred in our laboratory, because dysregulation of the same gene is known to cause developmental failure of embryos derived from induced pluripotent stem cells. There were also some DEGs in the extraembryonic tissues, which might explain the poor development of SCNT-derived placentas at early stages. These findings suggest that SCNT affects the embryonic and extraembryonic development differentially and might cause further deterioration in the embryonic lineage in a donor cell-specific manner. This could explain donor cell-dependent variations in cloning efficiency using SCNT.

Minkowski Functionals and Cluster Analysis for CMB Maps

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Novikov, D.; Feldman, Hume A.; Shandarin, Sergei F.

We suggest novel statistics for the CMB maps that are sensitive to non-Gaussian features. These statistics are natural generalizations of the geometrical and topological methods that have been already used in cosmology such as the cumulative distribution function and genus. We compute the distribution functions of the Partial Minkowski Functionals for the excursion set above or bellow a constant temperature threshold. Minkowski Functionals are additive and are translationally and rotationally invariant. Thus, they can be used for patchy and/or incomplete coverage. The technique is highly efficient computationally (it requires only O(N) operations, where N is the number of pixels per one threshold level). Further, the procedure makes it possible to split large data sets into smaller subsets. The full advantage of these statistics can be obtained only on very large data sets. We apply it to the 4-year DMR COBE data corrected for the Galaxy contamination as an illustration of the technique.

String Theory clues for the low-$\\ell$ CMB ?

CERN Document Server

Kitazawa, N.

2015-05-29

"Brane Supersymmetry Breaking" is a peculiar string-scale mechanism that can unpair Bose and Fermi excitations in orientifold models. It results from the simultaneous presence, in the vacuum, of collections of D-branes and orientifolds that are not mutually BPS, and is closely tied to the scale of string excitations. It also leaves behind, for a mixing of dilaton and internal breathing mode, an exponential potential that is just too steep for a scalar to emerge from the initial singularity while descending it. As a result, in this class of models the scalar can generically bounce off the exponential wall, and this dynamics brings along, in the power spectrum, an infrared depression typically followed by a pre-inflationary peak. We elaborate on a possible link between this type of bounce and the low-$\\ell$ end of the CMB angular power spectrum. For the first 32 multipoles, one can reach a 50 % reduction in $\\chi^{\\,2}$ with respect to the standard $\\Lambda$CDM setting.

The 'ventral organs' of Pycnogonida (Arthropoda are neurogenic niches of late embryonic and post-embryonic nervous system development.

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Georg Brenneis

Full Text Available Early neurogenesis in arthropods has been in the focus of numerous studies, its cellular basis, spatio-temporal dynamics and underlying genetic network being by now comparably well characterized for representatives of chelicerates, myriapods, hexapods and crustaceans. By contrast, neurogenesis during late embryonic and/or post-embryonic development has received less attention, especially in myriapods and chelicerates. Here, we apply (i immunolabeling, (ii histology and (iii scanning electron microscopy to study post-embryonic ventral nerve cord development in Pseudopallene sp., a representative of the sea spiders (Pycnogonida, the presumable sister group of the remaining chelicerates. During early post-embryonic development, large neural stem cells give rise to additional ganglion cell material in segmentally paired invaginations in the ventral ectoderm. These ectodermal cell regions - traditionally designated as 'ventral organs' - detach from the surface into the interior and persist as apical cell clusters on the ventral ganglion side. Each cluster is a post-embryonic neurogenic niche that features a tiny central cavity and initially still houses larger neural stem cells. The cluster stays connected to the underlying ganglionic somata cortex via an anterior and a posterior cell stream. Cell proliferation remains restricted to the cluster and streams, and migration of newly produced cells along the streams seems to account for increasing ganglion cell numbers in the cortex. The pycnogonid cluster-stream-systems show striking similarities to the life-long neurogenic system of decapod crustaceans, and due to their close vicinity to glomerulus-like neuropils, we consider their possible involvement in post-embryonic (perhaps even adult replenishment of olfactory neurons - as in decapods. An instance of a potentially similar post-embryonic/adult neurogenic system in the arthropod outgroup Onychophora is discussed. Additionally, we document two

Periconceptional maternal one-carbon biomarkers are associated with embryonic development according to the Carnegie stages.

Science.gov (United States)

Parisi, F; Rousian, M; Koning, A H J; Willemsen, S P; Cetin, I; Steegers-Theunissen, R P M

2017-03-01

.15; -0.01), P < 0.05). High tHcy concentrations (+2SD, 10.4 µmol/l) were associated with a delay of 1.6 days (95% CI: 1.5-1.7) in embryonic development compared with low concentrations (-2SD, 3.0 µmol/l). The study was performed in a tertiary care center, resulting in high rates of folic acid supplement use and comorbidity that may reduce the external validity of our findings. In periconceptional care, maternal I-C biomarkers should be taken into account as predictors of embryonic morphological development. Combining embryonic size measurements with morphological assessment could better define normal embryonic development. The work was funded by the Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands. RPMST is CSO of the startup company Slimmere Zorg and CEO of eHealth Care Solutions. The authors declare no conflicts of interest. Not applicable. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com

Next generation sub-millimeter wave focal plane array coupling concepts: an ESA TRP project to develop multichroic focal plane pixels for future CMB polarization experiments

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Trappe, N.; Bucher, M.; De Bernardis, P.; Delabrouille, J.; Deo, P.; DePetris, M.; Doherty, S.; Ghribi, A.; Gradziel, M.; Kuzmin, L.; Maffei, B.; Mahashabde, S.; Masi, S.; Murphy, J. A.; Noviello, F.; O'Sullivan, C.; Pagano, L.; Piacentini, F.; Piat, M.; Pisano, G.; Robinson, M.; Stompor, R.; Tartari, A.; van der Vorst, M.; Verhoeve, P.

2016-07-01

The main objective of this activity is to develop new focal plane coupling array concepts and technologies that optimise the coupling from reflector optics to the large number of detectors for next generation sub millimetre wave telescopes particularly targeting measurement of the polarization of the cosmic microwave background (CMB). In this 18 month TRP programme the consortium are tasked with developing, manufacturing and experimentally verifying a prototype multichroic pixel which would be suitable for the large focal plane arrays which will be demanded to reach the required sensitivity of future CMB polarization missions. One major development was to have multichroic operation to potentially reduce the required focal plane size of a CMB mission. After research in the optimum telescope design and definition of requirements based on a stringent science case review, a number of compact focal plane architecture concepts were investigated before a pixel demonstrator consisting of a planar mesh lens feeding a backend Resonant Cold Electron Bolometer RCEB for filtering and detection of the dual frequency signal was planned for manufacture and test. In this demonstrator the frequencies of the channels was chosen to be 75 and 105 GHz in the w band close to the peak CMB signal. In the next year the prototype breadboards will be developed to test the beams produced by the manufactured flat lenses fed by a variety of antenna configurations and the spectral response of the RCEBs will also be verified.

Strongly scale-dependent CMB dipolar asymmetry from super-curvature fluctuations

Energy Technology Data Exchange (ETDEWEB)

Byrnes, Christian [Department of Physics and Astronomy, University of Sussex, Brighton BN1 9QH (United Kingdom); Domènech, Guillem; Sasaki, Misao [Center for Gravitational Physics, Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Takahashi, Tomo, E-mail: C.Byrnes@sussex.ac.uk, E-mail: guillem.domenech@yukawa.kyoto-u.ac.jp, E-mail: misao@yukawa.kyoto-u.ac.jp, E-mail: tomot@cc.saga-u.ac.jp [Department of Physics, Saga University, Saga 840-8502 (Japan)

2016-12-01

We reconsider the observed CMB dipolar asymmetry in the context of open inflation, where a supercurvature mode might survive the bubble nucleation. If such a supercurvature mode modulates the amplitude of the curvature power spectrum, it would easily produce an asymmetry in the power spectrum. We show that current observational data can be accommodated in a three-field model, with simple quadratic potentials and a non-trivial field-space metric. Despite the presence of three fields, we believe this model is so far the simplest that can match current observations. We are able to match the observed strong scale dependence of the dipolar asymmetry, without a fine tuning of initial conditions, breaking slow roll or adding a feature to the evolution of any field.

Baryonic density of the universe: Big Bang nucleosynthesis versus CMB observations

International Nuclear Information System (INIS)

Vangioni-Flam, E.; Coc, A.; Casse, M.

2003-01-01

Thanks to recent nuclear reaction rate compilations (NACRE[2]) and new experimental and theoretical works in nuclear physics, we have updated Standard Big Bang Nucleosynthesis (SBBN) calculations. The results are compared to the most representative light element abundances, measured in pristine astrophysical media to derive the baryonic density of the Universe. We confront Ω b h 2 obtained in this study with other values deduced from recent independent approaches as the observations of the anisotropies of the Cosmic Microwave Background (BOOMERANG, CBI, DASI, MAXIMA and VSA experiments) or the Lyman-α forest at high redshifts. Comparison between these results is a test of their consistency and could provide a better determination of this important cosmological parameter

Primordial helium abundance from CMB: A constraint from recent observations and a forecast

International Nuclear Information System (INIS)

Ichikawa, Kazuhide; Sekiguchi, Toyokazu; Takahashi, Tomo

2008-01-01

We studied a constraint on the primordial helium abundance Y p from current and future observations of CMB. Using the currently available data from WMAP, ACBAR, CBI, and BOOMERANG, we obtained the constraint as Y p =0.25 -0.07 +0.10 at 68% confidence level. We also provide a forecast for the Planck experiment using the Markov chain Monte Carlo approach. In addition to forecasting the constraint on Y p , we investigate how assumptions for Y p affect constraints on the other cosmological parameters.

Bursts from the very early universe

International Nuclear Information System (INIS)

Silk, J.; Stodolsky, L.

2006-01-01

Bursts of weakly interacting particles such as neutrinos or even more weakly interacting particles such as wimps and gravitons from the very early universe would offer a much deeper 'look back time' to early epochs than is possible with photons. We consider some of the issues related to the existence of such bursts and their detectability. Characterizing the burst rate by a probability P per Hubble four-volume we find, for events in the radiation-dominated era, that the natural unit of description is the present intensity of the CMB times P. The existence of such bursts would make the observation of phenomena associated with very early times in cosmology at least conceptually possible. One might even hope to probe the transplanckian epoch if complexes more weakly interacting than the graviton can exist. Other conceivable applications include the potential detectability of the formation of 'pocket universes' in a multiverse

Isolation of a primate embryonic stem cell line.

OpenAIRE

Thomson, J A; Kalishman, J; Golos, T G; Durning, M; Harris, C P; Becker, R A; Hearn, J P

1995-01-01

Embryonic stem cells have the ability to remain undifferentiated and proliferate indefinitely in vitro while maintaining the potential to differentiate into derivatives of all three embryonic germ layers. Here we report the derivation of a cloned cell line (R278.5) from a rhesus monkey blastocyst that remains undifferentiated in continuous passage for > 1 year, maintains a normal XY karyotype, and expresses the cell surface markers (alkaline phosphatase, stage-specific embryonic antigen 3, st...

Detection of infectious bronchitis virus with the use of real-time quantitative reverse transcriptase-PCR and correlation with virus detection in embryonated eggs.

Science.gov (United States)

Roh, Ha-Jung; Hilt, Deborah A; Jackwood, Mark W

2014-09-01

Real-time quantitative reverse transcriptase-polymerase chain reaction (qRT-PCR) assays have been used to detect the presence of challenge virus when the efficacy of infectious bronchitis virus (IBV) vaccine against field viruses is being experimentally evaluated. However, federal guidelines for licensing IBV vaccines indicate that challenge-virus detection following vaccination is to be conducted in embryonated eggs. In this study, we examined qRT-PCR data with the use of universal and type-specific primers and probe sets for IBV detection and compared those data with challenge-virus detection in embryonated eggs to determine if the two methods of evaluating vaccine efficacy are comparable. In addition, we tested the qRT-PCR assays on thermocyclers from two different manufacturers. We found the universal IBV primers and probe set to be comparable to challenge-virus detection in embryonated eggs. However, for some IBV types (Mass41 and Conn on the SmartCycler II and Ark, Mass41, Conn, and GA98 on the ABI 7500) the qRT-PCR assay was more sensitive than virus detection in embryonated eggs. This may simply be due to the universal IBV qRT-PCR assay being more sensitive than virus detection in eggs or to the assay detecting nucleic acid from nonviable virus. This finding is important and needs to be considered when evaluating challenge-virus detection for vaccination and challenge studies, because qRT-PCR could potentially identify positive birds that would otherwise be negative by virus detection in embryonated eggs; thus it could lead to a more stringent measure of vaccine efficacy. We also found that the IBV type-specific primers and probe sets designed in this study were in general less sensitive than the universal IBV primers and probe set. Only the Ark-DPI-spedcific assay on the SmartCycler II and the Ark-DPI-, Mass41-, and DE072/GA98- (for detection of GA98 virus only) specific assays on the ABI 7500 were comparable in sensitivity to virus detection in eggs. We

Probing features in inflaton potential and reionization history with future CMB space observations

Science.gov (United States)

Hazra, Dhiraj Kumar; Paoletti, Daniela; Ballardini, Mario; Finelli, Fabio; Shafieloo, Arman; Smoot, George F.; Starobinsky, Alexei A.

2018-02-01

We consider the prospects of probing features in the primordial power spectrum with future Cosmic Microwave Background (CMB) polarization measurements. In the scope of the inflationary scenario, such features in the spectrum can be produced by local non-smooth pieces in an inflaton potential (smooth and quasi-flat in general) which in turn may originate from fast phase transitions during inflation in other quantum fields interacting with the inflaton. They can fit some outliers in the CMB temperature power spectrum which are unaddressed within the standard inflationary ΛCDM model. We consider Wiggly Whipped Inflation (WWI) as a theoretical framework leading to improvements in the fit to the Planck 2015 temperature and polarization data in comparison with the standard inflationary models, although not at a statistically significant level. We show that some type of features in the potential within the WWI models, leading to oscillations in the primordial power spectrum that extend to intermediate and small scales can be constrained with high confidence (at 3σ or higher confidence level) by an instrument as the Cosmic ORigins Explorer (CORE). In order to investigate the possible confusion between inflationary features and footprints from the reionization era, we consider an extended reionization history with monotonic increase of free electrons with decrease in redshift. We discuss the present constraints on this model of extended reionization and future predictions with CORE. We also project, to what extent, this extended reionization can create confusion in identifying inflationary features in the data.

Differentiation of embryonic stem cells towards hematopoietic cells: progress and pitfalls.

Science.gov (United States)

Tian, Xinghui; Kaufman, Dan S

2008-07-01

Hematopoietic development from embryonic stem cells has been one of the most productive areas of stem cell biology. Recent studies have progressed from work with mouse to human embryonic stem cells. Strategies to produce defined blood cell populations can be used to better understand normal and abnormal hematopoiesis, as well as potentially improve the generation of hematopoietic cells with therapeutic potential. Molecular profiling, phenotypic and functional analyses have all been utilized to demonstrate that hematopoietic cells derived from embryonic stem cells most closely represent a stage of hematopoiesis that occurs at embryonic/fetal developmental stages. Generation of hematopoietic stem/progenitor cells comparable to hematopoietic stem cells found in the adult sources, such as bone marrow and cord blood, still remains challenging. However, genetic manipulation of intrinsic factors during hematopoietic differentiation has proven a suitable approach to induce adult definitive hematopoiesis from embryonic stem cells. Concrete evidence has shown that embryonic stem cells provide a powerful approach to study the early stage of hematopoiesis. Multiple hematopoietic lineages can be generated from embryonic stem cells, although most of the evidence suggests that hematopoietic development from embryonic stem cells mimics an embryonic/fetal stage of hematopoiesis.

Totipotent Embryonic Stem Cells Arise in Ground-State Culture Conditions

DEFF Research Database (Denmark)

Morgani, Sophie M; Canham, Maurice A; Nichols, Jennifer

2013-01-01

Embryonic stem cells (ESCs) are derived from mammalian embryos during the transition from totipotency, when individual blastomeres can make all lineages, to pluripotency, when they are competent to make only embryonic lineages. ESCs maintained with inhibitors of MEK and GSK3 (2i) are thought...... not directly support Nanog-positive epiblast-like ESCs. Thus, 2i and LIF support a totipotent state comparable to early embryonic cells that coexpress embryonic and extraembryonic determinants....

The ‘Ventral Organs’ of Pycnogonida (Arthropoda) Are Neurogenic Niches of Late Embryonic and Post-Embryonic Nervous System Development

Science.gov (United States)

Brenneis, Georg; Scholtz, Gerhard

2014-01-01

Early neurogenesis in arthropods has been in the focus of numerous studies, its cellular basis, spatio-temporal dynamics and underlying genetic network being by now comparably well characterized for representatives of chelicerates, myriapods, hexapods and crustaceans. By contrast, neurogenesis during late embryonic and/or post-embryonic development has received less attention, especially in myriapods and chelicerates. Here, we apply (i) immunolabeling, (ii) histology and (iii) scanning electron microscopy to study post-embryonic ventral nerve cord development in Pseudopallene sp., a representative of the sea spiders (Pycnogonida), the presumable sister group of the remaining chelicerates. During early post-embryonic development, large neural stem cells give rise to additional ganglion cell material in segmentally paired invaginations in the ventral ectoderm. These ectodermal cell regions – traditionally designated as ‘ventral organs’ – detach from the surface into the interior and persist as apical cell clusters on the ventral ganglion side. Each cluster is a post-embryonic neurogenic niche that features a tiny central cavity and initially still houses larger neural stem cells. The cluster stays connected to the underlying ganglionic somata cortex via an anterior and a posterior cell stream. Cell proliferation remains restricted to the cluster and streams, and migration of newly produced cells along the streams seems to account for increasing ganglion cell numbers in the cortex. The pycnogonid cluster-stream-systems show striking similarities to the life-long neurogenic system of decapod crustaceans, and due to their close vicinity to glomerulus-like neuropils, we consider their possible involvement in post-embryonic (perhaps even adult) replenishment of olfactory neurons – as in decapods. An instance of a potentially similar post-embryonic/adult neurogenic system in the arthropod outgroup Onychophora is discussed. Additionally, we document two transient

Function of JARID2 in bovines during early embryonic development

Directory of Open Access Journals (Sweden)

Yao Fu

2017-12-01

Full Text Available Histone lysine modifications are important epigenetic modifications in early embryonic development. JARID2, which is a member of the jumonji demethylase protein family, is a regulator of early embryonic development and can regulate mouse development and embryonic stem cell (ESC differentiation by modifying histone lysines. JARID2 can affect early embryonic development by regulating the methylation level of H3K27me3, which is closely related to normal early embryonic development. To investigate the expression pattern of JARID2 and the effect of JARID2-induced H3K27 methylation in bovine oocytes and early embryonic stages, JARID2 mRNA expression and localization were detected in bovine oocytes and early embryos via qRT-PCR and immunofluorescence in the present study. The results showed that JARID2 is highly expressed in the germinal vesicle (GV, MII, 2-cell, 4-cell, 8-cell, 16-cell and blastocyst stages, but the relative expression level of JARID2 in bovine GV oocytes is significantly lower than that at other oocyte/embryonic stages (p < 0.05, and JARID2 is expressed primarily in the nucleus. We next detected the mRNA expression levels of embryonic development-related genes (OCT4, SOX2 and c-myc after JARID2 knockdown through JARID2-2830-siRNA microinjection to investigate the molecularpathwayunderlying the regulation of H3K27me3 by JARID2 during early embryonic development. The results showed that the relative expression levels of these genes in 2-cell embryos weresignificantly higher than those in the blastocyst stage, and expression levels were significantly increased after JARID2 knockdown. In summary, the present study identified the expression pattern of JARID2 in bovine oocytes and at each early embryonic stage, and the results suggest that JARID2 plays a key role in early embryonic development by regulating the expression of OCT4, SOX2 and c-myc via modification of H3K27me3 expression. This work provides new data for improvements in the

Planck 2015 results IX. Diffuse component separation: CMB maps

DEFF Research Database (Denmark)

Adam, R.; Ade, P. A R; Aghanim, N.

2016-01-01

We present foreground-reduced cosmic microwave background (CMB) maps derived from the full Planck data set in both temperature and polarization. Compared to the corresponding Planck 2013 temperature sky maps, the total data volume is larger by a factor of 3.2 for frequencies between 30 and 70 GHz......, and between 4.5 and 6.1μK averaged over pixels. The cosmological parameters derived from the analysis of temperature power spectra are in agreement at the 1σ level with the Planck 2015 likelihood. Unresolved mismatches between the noise properties of the data and simulations prevent a satisfactory description...... of the higher-order statistical properties of the polarization maps. Thus, the primary applications of these polarization maps are those that do not require massive simulations for accurate estimation of uncertainties, for instance estimation of cross-spectra and cross-correlations, or stacking analyses...

Background radiation fields as a probe of the large-scale matter distribution in the Universe

Energy Technology Data Exchange (ETDEWEB)

Kaiser, N [Cambridge Univ. (UK). Inst. of Astronomy

1982-03-01

A 'Swiss Cheese' model is used to calculate to order of magnitude the temperature fluctuation of the cosmic microwave background radiation (CMB) in a lumpy universe. The calculations are valid in a Friedmann background of arbitrary ..cap omega.. provided that matter has been dominant since the photons were last scattered. The inhomogeneities may be larger than the curvature scale, as is required to deal with fluctuations on a large angular scale in a low-density universe. This model is combined with observational limits on the fluctuations in the CMB to yield an upper limit to the present spectrum of inhomogeneities. The absence of any quadrupole anisotropy approximately > 3 x 10/sup -4/ sets a limit on the amplitude of lumps on scales very much greater than the present horizon. It is seen that, as shown by Peebles, for ..cap omega.. = 1 and a simple (Poisson) model the predicted ..delta..T/T(theta) is in remarkable accord with the recent measurements of quadrupole and 6/sup 0/ anisotropy. For a low-density model the predicted ..delta..T/T(theta) for large angles is markedly different. The limits on inhomogeneity from the isotropy of the X-ray background are briefly considered and they are found to be consistent with the microwave limits.

Background radiation fields as a probe of the large-scale matter distribution in the Universe

International Nuclear Information System (INIS)

Kaiser, N.

1982-01-01

A 'Swiss Cheese' model is used to calculate to order of magnitude the temperature fluctuation of the cosmic microwave background radiation (CMB) in a lumpy universe. The calculations are valid in a Friedmann background of arbitrary Ω provided that matter has been dominant since the photons were last scattered. The inhomogeneities may be larger than the curvature scale, as is required to deal with fluctuations on a large angular scale in a low-density universe. This model is combined with observational limits on the fluctuations in the CMB to yield an upper limit to the present spectrum of inhomogeneities. The absence of any quadrupole anisotropy approximately > 3 x 10 -4 sets a limit on the amplitude of lumps on scales very much greater than the present horizon. It is seen that, as shown by Peebles, for Ω = 1 and a simple (Poisson) model the predicted ΔT/T(theta) is in remarkable accord with the recent measurements of quadrupole and 6 0 anisotropy. For a low-density model the predicted ΔT/T(theta) for large angles is markedly different. The limits on inhomogeneity from the isotropy of the X-ray background are briefly considered and they are found to be consistent with the microwave limits. (author)

The effective gravitational decoupling between dark matter and the CMB

CERN Document Server

Voruz, Luc; Tram, Thomas

2014-01-01

We present a detailed and self-contained analytical derivation of the evolution of sub-horizon cosmological perturbations before decoupling, based on previous work by S. Weinberg. These solutions are valid in the minimal LCDM scenario, to first order in perturbation theory, in the tight-coupling limit and neglecting neutrino shear stress. We compare them to exact numerical solutions computed by a Boltzmann code, and we find the two to be in very good agreement. The analytic solutions show explicitly that CDM and the baryon-photon fluid effectively behave as separate self-gravitating fluids until the epoch of baryon drag. This in turn leads to the surprising conclusion that the CMB is much less sensitive to the clustering properties of minimally coupled Dark Matter models than what would be naively expected.

How the embryonic chick brain twists.

Science.gov (United States)

Chen, Zi; Guo, Qiaohang; Dai, Eric; Forsch, Nickolas; Taber, Larry A

2016-11-01

During early development, the tubular embryonic chick brain undergoes a combination of progressive ventral bending and rightward torsion, one of the earliest organ-level left-right asymmetry events in development. Existing evidence suggests that bending is caused by differential growth, but the mechanism for the predominantly rightward torsion of the embryonic brain tube remains poorly understood. Here, we show through a combination of in vitro experiments, a physical model of the embryonic morphology and mechanics analysis that the vitelline membrane (VM) exerts an external load on the brain that drives torsion. Our theoretical analysis showed that the force is of the order of 10 micronewtons. We also designed an experiment to use fluid surface tension to replace the mechanical role of the VM, and the estimated magnitude of the force owing to surface tension was shown to be consistent with the above theoretical analysis. We further discovered that the asymmetry of the looping heart determines the chirality of the twisted brain via physical mechanisms, demonstrating the mechanical transfer of left-right asymmetry between organs. Our experiments also implied that brain flexure is a necessary condition for torsion. Our work clarifies the mechanical origin of torsion and the development of left-right asymmetry in the early embryonic brain. © 2016 The Author(s).

Reconstruction of a direction-dependent primordial power spectrum from Planck CMB data

Science.gov (United States)

Durakovic, Amel; Hunt, Paul; Mukherjee, Suvodip; Sarkar, Subir; Souradeep, Tarun

2018-02-01

We consider the possibility that the primordial curvature perturbation is direction-dependent. To first order this is parameterised by a quadrupolar modulation of the power spectrum and results in statistical anisotropy of the CMB, which can be quantified using `bipolar spherical harmonics'. We compute these for the Planck DR2-2015 SMICA map and estimate the noise covariance from Planck Full Focal Plane 9 simulations. A constant quadrupolar modulation is detected with 2.2 σ significance, dropping to 2σ when the primordial power is assumed to scale with wave number k as a power law. Going beyond previous work we now allow the spectrum to have arbitrary scale-dependence. Our non-parametric reconstruction then suggests several spectral features, the most prominent at k ~ 0.006 Mpc‑1. When a constant quadrupolar modulation is fitted to data in the range 0.005 <= k/Mpc‑1 <= 0.008, its preferred directions are found to be related to the cosmic hemispherical asymmetry and the CMB dipole. To determine the significance we apply two test statistics to our reconstructions of the quadrupolar modulation from data, against reconstructions of realisations of noise only. With a test statistic sensitive only to the amplitude of the modulation, the reconstructions from the multipole range 30 <= l <= 1200 are unusual with 2.1σ significance. With the second test statistic, sensitive also to the direction, the significance rises to 6.9σ. Our approach is easily generalised to include other data sets such as polarisation, large-scale structure and forthcoming 21-cm line observations which will enable these anomalies to be investigated further.

Bursts from the very early universe

Energy Technology Data Exchange (ETDEWEB)

Silk, J. [Department of Physics, University of Oxford, Oxford OX1 3RH (United Kingdom); Stodolsky, L. [Max-Planck-Institut fuer Physik, Foehringer Ring 6, 80805 Munich (Germany)]. E-mail: les@mppmu.mpg.de

2006-07-27

Bursts of weakly interacting particles such as neutrinos or even more weakly interacting particles such as wimps and gravitons from the very early universe would offer a much deeper 'look back time' to early epochs than is possible with photons. We consider some of the issues related to the existence of such bursts and their detectability. Characterizing the burst rate by a probability P per Hubble four-volume we find, for events in the radiation-dominated era, that the natural unit of description is the present intensity of the CMB times P. The existence of such bursts would make the observation of pheno associated with very early times in cosmology at least conceptually possible. One might even hope to probe the transplanckian epoch if complexes more weakly interacting than the graviton can exist. Other conceivable applications include the potential detectability of the formation of 'pocket universes' in a multiverse.

Bioengineering Embryonic Stem Cell Microenvironments for the Study of Breast Cancer

Directory of Open Access Journals (Sweden)

Yubing Xie

2011-11-01

Full Text Available Breast cancer is the most prevalent disease amongst women worldwide and metastasis is the main cause of death due to breast cancer. Metastatic breast cancer cells and embryonic stem (ES cells display similar characteristics. However, unlike metastatic breast cancer cells, ES cells are nonmalignant. Furthermore, embryonic microenvironments have the potential to convert metastatic breast cancer cells into a less invasive phenotype. The creation of in vitro embryonic microenvironments will enable better understanding of ES cell-breast cancer cell interactions, help elucidate tumorigenesis, and lead to the restriction of breast cancer metastasis. In this article, we will present the characteristics of breast cancer cells and ES cells as well as their microenvironments, importance of embryonic microenvironments in inhibiting tumorigenesis, convergence of tumorigenic and embryonic signaling pathways, and state of the art in bioengineering embryonic microenvironments for breast cancer research. Additionally, the potential application of bioengineered embryonic microenvironments for the prevention and treatment of invasive breast cancer will be discussed.

Constraining quantum collapse inflationary models with CMB data

Energy Technology Data Exchange (ETDEWEB)

Benetti, Micol; Alcaniz, Jailson S. [Departamento de Astronomia, Observatório Nacional, 20921-400, Rio de Janeiro, RJ (Brazil); Landau, Susana J., E-mail: micolbenetti@on.br, E-mail: slandau@df.uba.ar, E-mail: alcaniz@on.br [Departamento de Física, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires and IFIBA, CONICET, Ciudad Universitaria, PabI, Buenos Aires 1428 (Argentina)

2016-12-01

The hypothesis of the self-induced collapse of the inflaton wave function was proposed as responsible for the emergence of inhomogeneity and anisotropy at all scales. This proposal was studied within an almost de Sitter space-time approximation for the background, which led to a perfect scale-invariant power spectrum, and also for a quasi-de Sitter background, which allows to distinguish departures from the standard approach due to the inclusion of the collapse hypothesis. In this work we perform a Bayesian model comparison for two different choices of the self-induced collapse in a full quasi-de Sitter expansion scenario. In particular, we analyze the possibility of detecting the imprint of these collapse schemes at low multipoles of the anisotropy temperature power spectrum of the Cosmic Microwave Background (CMB) using the most recent data provided by the Planck Collaboration. Our results show that one of the two collapse schemes analyzed provides the same Bayesian evidence of the minimal standard cosmological model ΛCDM, while the other scenario is weakly disfavoured with respect to the standard cosmology.

Oscillations in the CMB from Axion Monodromy Inflation

Energy Technology Data Exchange (ETDEWEB)

Flauger, Raphael; /Texas U.; McAllister, Liam; Pajer, Enrico; /Cornell U., Phys. Dept.; Westphal, Alexander; /SLAC /Stanford U., Phys. Dept.; Xu, Gang; /Cornell U., Phys. Dept.

2011-12-01

We study the CMB observables in axion monodromy inflation. These well-motivated scenarios for inflation in string theory have monomial potentials over super-Planckian field ranges, with superimposed sinusoidal modulations from instanton effects. Such periodic modulations of the potential can drive resonant enhancements of the correlation functions of cosmological perturbations, with characteristic modulations of the amplitude as a function of wavenumber. We give an analytical result for the scalar power spectrum in this class of models, and we determine the limits that present data places on the amplitude and frequency of modulations. Then, incorporating an improved understanding of the realization of axion monodromy inflation in string theory, we perform a careful study of microphysical constraints in this scenario. We find that detectable modulations of the scalar power spectrum are commonplace in well-controlled examples, while resonant contributions to the bispectrum are undetectable in some classes of examples and detectable in others. We conclude that resonant contributions to the spectrum and bispectrum are a characteristic signature of axion monodromy inflation that, in favorable cases, could be detected in near-future experiments.

Probing Models of Dark Matter and the Early Universe

Science.gov (United States)

Orlofsky, Nicholas David

This thesis discusses models for dark matter (DM) and their behavior in the early universe. An important question is how phenomenological probes can directly search for signals of DM today. Another topic of investigation is how the DM and other processes in the early universe must evolve. Then, astrophysical bounds on early universe dynamics can constrain DM. We will consider these questions in the context of three classes of DM models--weakly interacting massive particles (WIMPs), axions, and primordial black holes (PBHs). Starting with WIMPs, we consider models where the DM is charged under the electroweak gauge group of the Standard Model. Such WIMPs, if generated by a thermal cosmological history, are constrained by direct detection experiments. To avoid present or near-future bounds, the WIMP model or cosmological history must be altered in some way. This may be accomplished by the inclusion of new states that coannihilate with the WIMP or a period of non-thermal evolution in the early universe. Future experiments are likely to probe some of these altered scenarios, and a non-observation would require a high degree of tuning in some of the model parameters in these scenarios. Next, axions, as light pseudo-Nambu-Goldstone bosons, are susceptible to quantum fluctuations in the early universe that lead to isocurvature perturbations, which are constrained by observations of the cosmic microwave background (CMB). We ask what it would take to allow axion models in the face of these strong CMB bounds. We revisit models where inflationary dynamics modify the axion potential and discuss how isocurvature bounds can be relaxed, elucidating the difficulties in these constructions. Avoiding disruption of inflationary dynamics provides important limits on the parameter space. Finally, PBHs have received interest in part due to observations by LIGO of merging black hole binaries. We ask how these PBHs could arise through inflationary models and investigate the opportunity

Stepwise development of hematopoietic stem cells from embryonic stem cells.

Directory of Open Access Journals (Sweden)

Kenji Matsumoto

Full Text Available The cellular ontogeny of hematopoietic stem cells (HSCs remains poorly understood because their isolation from and their identification in early developing small embryos are difficult. We attempted to dissect early developmental stages of HSCs using an in vitro mouse embryonic stem cell (ESC differentiation system combined with inducible HOXB4 expression. Here we report the identification of pre-HSCs and an embryonic type of HSCs (embryonic HSCs as intermediate cells between ESCs and HSCs. Both pre-HSCs and embryonic HSCs were isolated by their c-Kit(+CD41(+CD45(- phenotype. Pre-HSCs did not engraft in irradiated adult mice. After co-culture with OP9 stromal cells and conditional expression of HOXB4, pre-HSCs gave rise to embryonic HSCs capable of engraftment and long-term reconstitution in irradiated adult mice. Blast colony assays revealed that most hemangioblast activity was detected apart from the pre-HSC population, implying the early divergence of pre-HSCs from hemangioblasts. Gene expression profiling suggests that a particular set of transcripts closely associated with adult HSCs is involved in the transition of pre-HSC to embryonic HSCs. We propose an HSC developmental model in which pre-HSCs and embryonic HSCs sequentially give rise to adult types of HSCs in a stepwise manner.

Decoupling in an expanding universe: backreaction barely constrains short distance effects in the cosmic microwave background

CERN Document Server

Greene, B R; Shiu, G; Van der Schaar, J P; Greene, Brian R.; Schalm, Koenraad; Shiu, Gary; Schaar, Jan Pieter van der

2005-01-01

We clarify the status of transplanckian effects on the cosmic microwave background (CMB) anisotropy. We do so using the boundary effective action formalism of hep-th/0401164 which accounts quantitatively for the cosmological vacuum ambiguity. In this formalism we can clearly 1) delineate the validity of cosmological effective actions in an expanding universe. The corollary of the initial state ambiguity is the existence of an earliest time. The inability of an effective action to describe physics before this time demands that one sets initial conditions on the earliest time hypersurface. A calculation then shows that CMB anisotropy measurements are generically sensitive to high energy corrections to the initial conditions. 2) We compute the one-loop contribution to the stress-tensor due to high-energy physics corrections to an arbitrary cosmological initial state. We find that phenomenological bounds on the backreaction do not lead to strong constraints on the coefficient of the leading boundary irrelevant op...

The primary role of zebrafish nanog is in extra-embryonic tissue.

Science.gov (United States)

Gagnon, James A; Obbad, Kamal; Schier, Alexander F

2018-01-09

The role of the zebrafish transcription factor Nanog has been controversial. It has been suggested that Nanog is primarily required for the proper formation of the extra-embryonic yolk syncytial layer (YSL) and only indirectly regulates gene expression in embryonic cells. In an alternative scenario, Nanog has been proposed to directly regulate transcription in embryonic cells during zygotic genome activation. To clarify the roles of Nanog, we performed a detailed analysis of zebrafish nanog mutants. Whereas zygotic nanog mutants survive to adulthood, maternal-zygotic (MZ nanog ) and maternal mutants exhibit developmental arrest at the blastula stage. In the absence of Nanog, YSL formation and epiboly are abnormal, embryonic tissue detaches from the yolk, and the expression of dozens of YSL and embryonic genes is reduced. Epiboly defects can be rescued by generating chimeric embryos of MZ nanog embryonic tissue with wild-type vegetal tissue that includes the YSL and yolk cell. Notably, cells lacking Nanog readily respond to Nodal signals and when transplanted into wild-type hosts proliferate and contribute to embryonic tissues and adult organs from all germ layers. These results indicate that zebrafish Nanog is necessary for proper YSL development but is not directly required for embryonic cell differentiation. © 2018. Published by The Company of Biologists Ltd.

Pathways in pluripotency and differentiation of embryonic cells

NARCIS (Netherlands)

du Puy, L.

2010-01-01

Pluripotency - the potential to differentiate into derivatives of the three embryonic germ layers endoderm, ectoderm and mesoderm - is the main characteristic of embryonic stem (ES) cells. ES cells are derived from the inner cell mass (ICM) of a pre-implantation blastocyst and can self-renew

Cosmological constraints on radion evolution in the universal extra dimension model

International Nuclear Information System (INIS)

Chan, K. C.; Chu, M.-C.

2008-01-01

The constraints on the radion evolution in the universal extra dimension (UED) model from cosmic microwave background (CMB) and Type Ia supernovae (SNe Ia) data are studied. In the UED model, where both the gravity and standard model fields can propagate in the extra dimensions, the evolution of the extra-dimensional volume, the radion, induces variation of fundamental constants. We discuss the effects of variation of the relevant constants in the context of UED for the CMB power spectrum and SNe Ia data. We then use the three-year WMAP data to constrain the radion evolution at z∼1100, and the 2σ constraint on ρ/ρ 0 (ρ is a function of the radion, to be defined in the text) is [-8.8,6.6]x10 -13 yr -1 . The SNe Ia gold sample yields a constraint on ρ/ρ 0 , for redshift between 0 and 1, to be [-4.7,14]x10 -13 yr -1 . Furthermore, the constraints from SNe Ia can be interpreted as bounds on the evolution QCD scale parameter, Λ QCD /Λ QCD,0 , [-1.4,2.8]x10 -11 yr -1 , without reference to the UED model.

Progress in Precision Measurements of the Cosmic Microwave Background

Energy Technology Data Exchange (ETDEWEB)

Bernardis, P. de; Calvo, M.; Coppolecchia, A.; Cruciani, A.; Giordano, C.; Masi, S.; Nati, F.; Salatino, M.; Schillaci, A. [Dipartimento di Fisica, Universita La Sapienza, P.le A. Moro 2, 00185 Roma (Italy)

2011-08-15

High precision measurements of the Cosmic Microwave Background (CMB) represent one of the most difficult challenges in observational cosmology, but promise to unveil the mysteries of the very early Universe and of the birth of structures. Three observables are available. The small polarized CMB signal is probably carrying a signature of the early inflationary dynamics of the Universe. It is, however, embedded in overwhelming noise, systematic effects, and polarized foreground. The imprint of the large scale structure in the universe is present in the small-scale anisotropy of the CMB and in its spectral signatures (secondary anisotropy), again mixed with foreground contaminants. Low-level non-Gaussian components of CMB anisotropy and polarization also provide a very promising way to constrain inflation and the physics of ultra-high energies, if foregrounds can be efficiently separated from the measured signal. If measured with high precision, as required by the science issues above, the spectra of CMB anisotropy and polarization also constrain efficiently neutrino properties, hence their interest in this conference. Here we summarize the current status of CMB measurements, dominated by the Planck survey, and delineate the forthcoming activities, needed to exploit the huge scientific potential of precision measurements of the CMB, including the detection of neutrino masses.

Impact of theoretical assumptions in the determination of the neutrino effective number from future CMB measurements

Science.gov (United States)

Capparelli, Ludovico; Di Valentino, Eleonora; Melchiorri, Alessandro; Chluba, Jens

2018-03-01

One of the major goals of future cosmic microwave background (CMB) measurements is the accurate determination of the effective number of neutrinos Neff. Reaching an experimental sensitivity of Δ Neff=0.013 could indeed falsify the presence of any nonstandard relativistic particles at 95% C.L. In this paper, we test how this future constraint can be affected by the removal of two common assumptions: a negligible running of the inflationary spectral index nrun and a precise determination of the neutron lifetime τn. We first show that the constraints on Neff could be significantly biased by the unaccounted presence of a running of the spectral index. Considering the Stage-IV experiment, a negative running of d n /d ln k =-0.002 could mimic a positive variation of Δ Neff=0.03 . Moreover, given the current discrepancies between experimental measurements of the neutron lifetime τn, we show that the assumption of a conservative error of Δ τn˜10 s could cause a systematic error of Δ Neff=0.02 . Complementary cosmological constraints on the running of the spectral index and a solution to the neutron lifetime discrepancy are therefore needed for an accurate and reliable future CMB bound of Neff at the percent level.

Notch signaling activation in human embryonic stem cells is required for embryonic but not trophoblastic lineage commitment

OpenAIRE

Yu, Xiaobing; Zou, Jizhong; Ye, Zhaohui; Hammond, Holly; Chen, Guibin; Tokunaga, Akinori; Mali, Prashant; Li, Yue-Ming; Civin, Curt; Gaiano, Nicholas; Cheng, Linzhao

2008-01-01

The Notch signaling pathway plays important roles in cell fate determination during embryonic development and adult life. In this study, we focus on the role of Notch signaling in governing cell fate choices in human embryonic stem (hES) cells. Using genetic and pharmacological approaches, we achieved both blockade and conditional activation of Notch signaling in several hES cell lines. We report here that activation of Notch signaling is required for undifferentiated hES cells to form the pr...

CMB seen through random Swiss Cheese

Energy Technology Data Exchange (ETDEWEB)

Lavinto, Mikko; Räsänen, Syksy, E-mail: mikko.lavinto@helsinki.fi, E-mail: syksy.rasanen@iki.fi [Physics Department, University of Helsinki and Helsinki Institute of Physics, P.O. Box 64, FIN-00014, University of Helsinki (Finland)

2015-10-01

We consider a Swiss Cheese model with a random arrangement of Lemaȋtre-Tolman-Bondi holes in ΛCDM cheese. We study two kinds of holes with radius r{sub b}=50 h{sup −1} Mpc, with either an underdense or an overdense centre, called the open and closed case, respectively. We calculate the effect of the holes on the temperature, angular diameter distance and, for the first time in Swiss Cheese models, shear of the CMB . We quantify the systematic shift of the mean and the statistical scatter, and calculate the power spectra. In the open case, the temperature power spectrum is three orders of magnitude below the linear ISW spectrum. It is sensitive to the details of the hole, in the closed case the amplitude is two orders of magnitude smaller. In contrast, the power spectra of the distance and shear are more robust, and agree with perturbation theory and previous Swiss Cheese results. We do not find a statistically significant mean shift in the sky average of the angular diameter distance, and obtain the 95% limit |Δ D{sub A}/ D-bar {sub A}|∼< 10{sup −4}. We consider the argument that areas of spherical surfaces are nearly unaffected by perturbations, which is often invoked in light propagation calculations. The closed case is consistent with this at 1σ, whereas in the open case the probability is only 1.4%.

Somatic Donor Cell Type Correlates with Embryonic, but Not Extra-Embryonic, Gene Expression in Postimplantation Cloned Embryos

Science.gov (United States)

Inoue, Kimiko; Ogura, Atsuo

2013-01-01

The great majority of embryos generated by somatic cell nuclear transfer (SCNT) display defined abnormal phenotypes after implantation, such as an increased likelihood of death and abnormal placentation. To gain better insight into the underlying mechanisms, we analyzed genome-wide gene expression profiles of day 6.5 postimplantation mouse embryos cloned from three different cell types (cumulus cells, neonatal Sertoli cells and fibroblasts). The embryos retrieved from the uteri were separated into embryonic (epiblast) and extraembryonic (extraembryonic ectoderm and ectoplacental cone) tissues and were subjected to gene microarray analysis. Genotype- and sex-matched embryos produced by in vitro fertilization were used as controls. Principal component analysis revealed that whereas the gene expression patterns in the embryonic tissues varied according to the donor cell type, those in extraembryonic tissues were relatively consistent across all groups. Within each group, the embryonic tissues had more differentially expressed genes (DEGs) (>2-fold vs. controls) than did the extraembryonic tissues (Pcloning efficiency using SCNT. PMID:24146866

A practical guide for the identification of membrane and plasma membrane proteins in human embryonic stem cells and human embryonal carcinoma cells.

NARCIS (Netherlands)

Dormeyer, W.; van Hoof, D.; Mummery, C.L.; Krijgsveld, J.; Heck, A.

2008-01-01

The identification of (plasma) membrane proteins in cells can provide valuable insights into the regulation of their biological processes. Pluripotent cells such as human embryonic stem cells and embryonal carcinoma cells are capable of unlimited self-renewal and share many of the biological

Childhood Central Nervous System Embryonal Tumors (PDQ®)—Health Professional Version

Science.gov (United States)

Pediatric CNS embryonal tumors are a collection of heterogeneous lesions (medulloblastoma, and nonmedulloblastoma). Molecular genetic studies are used to classify embryonal tumors, stratify risk, and plan treatment. Get detailed information about tumor biology, diagnosis, prognosis, and treatment of untreated and recurrent CNS embryonal tumors in this summary for clinicians.

Do joint CMB and HST data support a scale invariant spectrum?

Energy Technology Data Exchange (ETDEWEB)

Benetti, Micol; Graef, Leila L.; Alcaniz, Jailson S., E-mail: micolbenetti@on.br, E-mail: leilagraef@on.br, E-mail: alcaniz@on.br [Departamento de Astronomia, Observatório Nacional, 20921-400, Rio de Janeiro, RJ (Brazil)

2017-04-01

We combine current measurements of the local expansion rate, H {sub 0}, and Big Bang Nucleosynthesis (BBN) estimates of helium abundance with the latest cosmic microwave background (CMB) data from the Planck Collaboration to discuss the observational viability of the scale invariant Harrison-Zeldovch-Peebles (HZP) spectrum. We also analyze some of its extensions, namely, HZP + Y {sub P} and HZP + N {sub eff}, where Y {sub P} is the primordial helium mass fraction and N {sub eff} is the effective number of relativistic degrees of freedom. We perform a Bayesian analysis and show that the latter model is favored with respect to the standard cosmology for values of N {sub eff} lying in the interval 3.70 ± 0.13 (1σ), which is currently allowed by some independent analyses.

File list: Unc.Emb.05.AllAg.Embryonic_pancreas [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Emb.20.AllAg.Embryonic_pancreas [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Emb.10.AllAg.Embryonic_pancreas [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: Unc.Emb.50.AllAg.Embryonic_pancreas [Chip-atlas[Archive

Lifescience Database Archive (English)

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Neutrino mass and the reionization history of the Universe

International Nuclear Information System (INIS)

Popa, L.A.; Burigana, C.; Mandolesi, N.

2005-01-01

We investigate the role of a HDM component in the form of the three massive neutrino flavors for the reionization history of the Universe. Assuming a flat background cosmology described by the best fit power low ΛCDM model with WMAP data (Ω b h 2 =0.024, Ω m h 2 =0.14, h=0.72), we analyze the role of the neutrino mass for the properties of the gas in the intergalactic medium (IGM), showing that the temporal evolution of the hydrogen and helium ionization fractions are sensitive to the neutrino mass, with important implications for the CMB anisotropy and polarization angular power spectra

Motion induced second order temperature and y-type anisotropies after the subtraction of linear dipole in the CMB maps

International Nuclear Information System (INIS)

Sunyaev, Rashid A.; Khatri, Rishi

2013-01-01

y-type spectral distortions of the cosmic microwave background allow us to detect clusters and groups of galaxies, filaments of hot gas and the non-uniformities in the warm hot intergalactic medium. Several CMB experiments (on small areas of sky) and theoretical groups (for full sky) have recently published y-type distortion maps. We propose to search for two artificial hot spots in such y-type maps resulting from the incomplete subtraction of the effect of the motion induced dipole on the cosmic microwave background sky. This dipole introduces, at second order, additional temperature and y-distortion anisotropy on the sky of amplitude few μK which could potentially be measured by Planck HFI and Pixie experiments and can be used as a source of cross channel calibration by CMB experiments. This y-type distortion is present in every pixel and is not the result of averaging the whole sky. This distortion, calculated exactly from the known linear dipole, can be subtracted from the final y-type maps, if desired

File list: Pol.Emb.05.AllAg.Embryonic_palates [Chip-atlas[Archive

Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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Lifescience Database Archive (English)

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Culture conditions for bovine embryonic stem cell-like cells isolated from blastocysts after external fertilization

OpenAIRE

Jin, Muzi; Wu, Asga; Dorzhin, Sergei; Yue, Qunhua; Ma, Yuzhen; Liu, Dongjun

2012-01-01

Although isolation and characterization of embryonic stem cells have been successful in cattle, maintenance of bovine embryonic stem cells in culture remains difficult. In this study, we compared different methods of cell passaging, feeder cell layers and medium conditions for bovine embryonic stem cell-like cells. We found that a murine embryonic fibroblast feeder layer is more suitable for embryonic stem cell-like cells than bovine embryonic fibroblasts. When murine embryonic fibroblasts we...

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Lifescience Database Archive (English)

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Mapping the stem cell state: eight novel human embryonic stem and embryonal carcinoma cell antibodies

DEFF Research Database (Denmark)

Wright, A; Andrews, N; Bardsley, K

2011-01-01

The antigenic profile of human embryonic stem (ES) and embryonal carcinoma (EC) cells has served as a key element of their characterization, with a common panel of surface and intracellular markers now widely used. Such markers have been used to identify cells within the 'undifferentiated state...... of reactivity for all antibodies against both ES and EC cells, suggesting that these markers will afford recognition of unique sub-states within the undifferentiated stem cell compartment....... and EC cells, and herein describe their characterization. The reactivity of these antibodies against a range of cell lines is reported, as well as their developmental regulation, basic biochemistry and reactivity in immunohistochemistry of testicular germ cell tumours. Our data reveal a range...

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Lifescience Database Archive (English)

Full Text Available His.Emb.10.AllAg.Embryonic_trunk mm9 Histone Embryo Embryonic trunk SRX093317,SRX09...3316 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/assembled/His.Emb.10.AllAg.Embryonic_trunk.bed ...

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File list: Unc.Emb.50.AllAg.Embryonic_heart [Chip-atlas[Archive

Lifescience Database Archive (English)

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Interacting scalar tensor cosmology in light of SNeIa, CMB, BAO and OHD observational data sets

International Nuclear Information System (INIS)

Rabiei, Sayed Wrya; Saaidi, Khaled; Sheikhahmadi, Haidar; Aghamohammadi, Ali

2016-01-01

In this work, an interacting chameleon-like scalar field scenario, by considering SNeIa, CMB, BAO, and OHD data sets, is investigated. In fact, the investigation is realized by introducing an ansatz for the effective dark energy equation of state, which mimics the behavior of chameleon-like models. Based on this assumption, some cosmological parameters, including the Hubble, deceleration, and coincidence parameters, in such a mechanism are analyzed. It is realized that, to estimate the free parameters of a theoretical model, by regarding the systematic errors it is better that the whole of the above observational data sets would be considered. In fact, if one considers SNeIa, CMB, and BAO, but disregards OHD, it maybe leads to different results. Also, to get a better overlap between the contours with the constraint χ m 2 ≤ 1, the χ T 2 function could be re-weighted. The relative probability functions are plotted for marginalized likelihood L(Ω m0 , ω 1 , β) according to the two dimensional confidence levels 68.3, 90, and 95.4%. Meanwhile, the value of the free parameters which maximize the marginalized likelihoods using the above confidence levels are obtained. In addition, based on these calculations the minimum value of χ 2 based on the free parameters of the ansatz for the effective dark energy equation of state is achieved. (orig.)

Generation of hematopoietic lineage cells from embryonic like cells

Directory of Open Access Journals (Sweden)

Gholam Reza Khamisipour

2014-10-01

Full Text Available Background: Epigenetic reprogramming of somatic cells into embryonic stem cells has attracted much attention, because of the potential for stem cell transplantation and compatibility with recipient. However, the therapeutic application of either nuclear transfer or nuclear fusion of somatic cell has been hindered by technical complications as well as ethical objections. Recently, a new method is reported whereby ectopic expression of embryonic specific transcription factors was shown to induce fibroblasts to become embryonic like SCs (induced pluripotent stem cells. A major limitation of this method is the use of potentially harmful genome integrating viruses such as reto- or lentivirus. The main aim of this investigation was generation of human hematopoietic stem cells from induced fibroblasts by safe adenovectors carrying embryonically active genes. Material and Methods: Isolated fibroblasts from foreskin were expanded and recombinant adenoviruses carrying human Sox2, Oct4, Klf4, cMyc genes were added to culture. After formation of embryonic like colonies and cell expansion, they were transferred to embryonic media without bFGF, and embryoid bodies were cultured on stromal and non-stromal differentiation media for 14 days. Results: Expression of CD34 gene and antigenic markers, CD34, CD38 & CD133 in stromal culture showed significant difference with non-differentiation and non-stromal media. Conclusion: These findings show high hematopoietic differentiation rate of Adeno-iPS cells in stromal culture and no need to use growth factors. While, there was no difference between non-differentiation and non-stromal media.

A String-Inspired Model for the Low-$\\ell$ CMB

CERN Document Server

Kitazawa, N.

2015-07-09

We present a semi--analytic exploration of some low--$\\ell$ angular power spectra inspired by "Brane Supersymmetry Breaking". This mechanism splits Bose and Fermi excitations in String Theory, leaving behind an exponential potential that is just too steep for the inflaton to emerge from the initial singularity while descending it. As a result, the scalar generically bounces against the exponential wall, which typically introduces an infrared depression and a pre--inflationary peak in the power spectrum of scalar perturbations. We elaborate on a possible link between this phenomenon and the low--$\\ell$ CMB. For the first 32 multipoles, combining the hard exponential with a milder one leading to $n_s\\simeq 0.96$ and with a small gaussian bump we have attained a reduction of $\\chi^{\\,2}$ to about 46% of the standard $\\Lambda$CDM setting, with both WMAP9 and PLANCK 2013 data. This result corresponds to a $\\chi^{\\,2}/DOF$ of about 0.45, to be compared with a $\\Lambda$CDM value of about 0.85. The preferred choices ...

Studying Heavy Ion Collisions Using Methods From Cosmic Microwave Background (CMB Analysis

Directory of Open Access Journals (Sweden)

Gaardhøje J. J.

2014-04-01

Full Text Available We present and discuss a framework for studying the morphology of high-multiplicity events from relativistic heavy ion collisions using methods commonly employed in the analysis of the photons from the Cosmic Microwave Background (CMB. The analysis is based on the decomposition of the distribution of the number density of (charged particles expressed in polar and azimuthal coordinates into a sum of spherical harmonic functions. We present an application of the method exploting relevant symmetries to the study of azimuthal correlations arizing from collective flow among charged particles produced in relativistic heavy ion collisions. We discuss perspectives for event-by- event analyses, which with increasing collision energy will eventually open entirely new dimensions in the study of ultrarelaticistic heavy ion reactions.

CMB anomalies and the effects of local features of the inflaton potential

Energy Technology Data Exchange (ETDEWEB)

Cadavid, Alexander Gallego [Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); ICRANet, Pescara (Italy); Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Romano, Antonio Enea [Kyoto University, Yukawa Institute for Theoretical Physics, Kyoto (Japan); University of Torino, Department of Physics, Turin (Italy); Universidad de Antioquia, Instituto de Fisica, Medellin (Colombia); Gariazzo, Stefano [University of Torino, Department of Physics, Turin (Italy); INFN, Sezione di Torino, Turin (Italy); Instituto de Fisica Corpuscular (CSIC-Universitat de Valencia), Paterna, Valencia (Spain)

2017-04-15

Recent analysis of the WMAP and Planck data have shown the presence of a dip and a bump in the spectrum of primordial perturbations at the scales k = 0.002 Mpc{sup -1}, respectively. We analyze for the first time the effects of a local feature in the inflaton potential to explain the observed deviations from scale invariance in the primordial spectrum. We perform a best-fit analysis of the cosmic microwave background (CMB) radiation temperature and polarization data. The effects of the features can improve the agreement with observational data respect to the featureless model. The best-fit local feature affects the primordial curvature spectrum mainly in the region of the bump, leaving the spectrum unaffected on other scales. (orig.)

Cardiomyocytes derived from embryonic stem cells resemble cardiomyocytes of the embryonic heart tube

NARCIS (Netherlands)

Fijnvandraat, Arnoud C.; van Ginneken, Antoni C. G.; de Boer, Piet A. J.; Ruijter, Jan M.; Christoffels, Vincent M.; Moorman, Antoon F. M.; Lekanne Deprez, Ronald H.

2003-01-01

OBJECTIVE: After formation of the linear heart tube a chamber-specific program of gene expression becomes active that underlies the formation of the chamber myocardium. To assess whether this program is recapitulated in in vitro differentiated embryonic stem cells, we performed qualitative and

CNS embryonal tumours: WHO 2016 and beyond.

Science.gov (United States)

Pickles, J C; Hawkins, C; Pietsch, T; Jacques, T S

2018-02-01

Embryonal tumours of the central nervous system (CNS) present a significant clinical challenge. Many of these neoplasms affect young children, have a very high mortality and therapeutic strategies are often aggressive with poor long-term outcomes. There is a great need to accurately diagnose embryonal tumours, predict their outcome and adapt therapy to the individual patient's risk. For the first time in 2016, the WHO classification took into account molecular characteristics for the diagnosis of CNS tumours. This integration of histological features with genetic information has significantly changed the diagnostic work-up and reporting of tumours of the CNS. However, this remains challenging in embryonal tumours due to their previously unaccounted tumour heterogeneity. We describe the recent revisions made to the 4th edition of the WHO classification of CNS tumours and review the main changes, while highlighting some of the more common diagnostic testing strategies. © 2017 British Neuropathological Society.

Tensor Minkowski Functionals: first application to the CMB

Energy Technology Data Exchange (ETDEWEB)

Ganesan, Vidhya [Indian Institute of Astrophysics, Koramangala II Block, Bangalore 560 034 (India); Chingangbam, Pravabati, E-mail: vidhya@iiap.res.in, E-mail: prava@iiap.res.in [Indian Institute of Science, C.V. Raman Ave, Bangalore 560 012 (India)

2017-06-01

Tensor Minkowski Functionals (TMFs) are tensor generalizations of the usual Minkowski Functionals which are scalar quantities. We introduce them here for use in cosmological analysis, in particular to analyze the Cosmic Microwave Background (CMB) radiation. They encapsulate information about the shapes of structures and the orientation of distributions of structures. We focus on one of the TMFs, namely W {sub 2}{sup 1,1}, which is the (1,1) rank tensor generalization of the genus. The ratio of the eigenvalues of the average of W {sub 2}{sup 1,1} over all structures, α, encodes the net orientation of the structures; and the average of the ratios of the eigenvalues of W {sub 2}{sup 1,1} for each structure, β, encodes the net intrinsic anisotropy of the structures. We have developed a code that computes W {sub 2}{sup 1,1}, and from it α and β, for a set of structures on the 2-dimensional Euclidean plane. We use it to compute α and β as functions of chosen threshold levels for simulated Gaussian and isotropic CMB temperature and E mode fields. We obtain the value of α to be one for both temperature and E mode, which means that we recover the statistical isotropy of density fluctuations that we input in the simulations. We find that the standard ΛCDM model predicts a charateristic shape of β for temperature and E mode as a function of the threshold, and the average over thresholds is β∼ 0.62 for temperature and β∼ 0.63 for E mode. Accurate measurements of α and β can be used to test the standard model of cosmology and to search for deviations from it. For this purpose we compute α and β for temperature and E mode data of various data sets from PLANCK mission. We compare the values measured from observed data with those obtained from simulations to which instrument beam and noise characteristics of the 44GHz frequency channel have been added (which are provided as part of the PLANCK data release). We find very good agreement of β and α between all

Porcine embryonic stem cells

DEFF Research Database (Denmark)

Hall, Vanessa Jane

2008-01-01

The development of porcine embryonic stem cell lines (pESC) has received renewed interest given the advances being made in the production of immunocompatible transgenic pigs. However, difficulties are evident in the production of pESCs in-vitro. This may largely be attributable to differences...

File list: His.Emb.20.AllAg.embryonic_skin [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Emb.50.AllAg.embryonic_skin [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: His.Emb.05.AllAg.embryonic_skin [Chip-atlas[Archive

Lifescience Database Archive (English)

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Are there factors preventing cancer development during embryonic life

International Nuclear Information System (INIS)

Einhorn, L.

1983-01-01

On the basis of the following literature observations, a hypothesis is advanced that the development of cancer is actively inhibited during embryonic life. Although the processes of cell differentiation and proliferation are - without comparison - most pronounced during embryonic life, cancer is rarely found in the newborn and is seldom a cause of neonatal death or spontaneous abortion. Attempts to induce cancer in early-stage animal embryos by irradiation or by transplacental chemical carcinogenesis have been unsuccessful, even when exposed animals have been observed throughout their lifetime. After the period of major organogenesis, however, the embryos become susceptible to carcinogenesis. In humans, the most common embryonic tumors arise in tissues which have an unusually late ongoing development and are still partly immature at or shortly before birth. For many human embryonic tumors the survival rates are higher, and spontaneous regression more frequent, in younger children, i.e. prognosis is age-dependent. Thus, although cancer generally appears in tissues capable of proliferation and differentiation, induction of malignancy in the developmentally most active tissues seems to be beset with difficulty. One possible explanation for this paradox could be that cancer is controlled by the regulators influencing development, regulators that are most active during embryonic life. (Auth.)

Tension (re)builds: Biophysical mechanisms of embryonic wound repair.

Science.gov (United States)

Zulueta-Coarasa, Teresa; Fernandez-Gonzalez, Rodrigo

2017-04-01

Embryonic tissues display an outstanding ability to rapidly repair wounds. Epithelia, in particular, serve as protective layers that line internal organs and form the skin. Thus, maintenance of epithelial integrity is of utmost importance for animal survival, particularly at embryonic stages, when an immune system has not yet fully developed. Rapid embryonic repair of epithelial tissues is conserved across species, and involves the collective migration of the cells around the wound. The migratory cell behaviours associated with wound repair require the generation and transmission of mechanical forces, not only for the cells to move, but also to coordinate their movements. Here, we review the forces involved in embryonic wound repair. We discuss how different force-generating structures are assembled at the molecular level, and the mechanisms that maintain the balance between force-generating structures as wounds close. Finally, we describe the mechanisms that cells use to coordinate the generation of mechanical forces around the wound. Collective cell movements and their misregulation have been associated with defective tissue repair, developmental abnormalities and cancer metastasis. Thus, we propose that understanding the role of mechanical forces during embryonic wound closure will be crucial to develop therapeutic interventions that promote or prevent collective cell movements under pathological conditions. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Endolymphatic potassium of the chicken vestibule during embryonic development.

Science.gov (United States)

Masetto, Sergio; Zucca, Giampiero; Bottà, Luisa; Valli, Paolo

2005-08-01

The endolymph fills the lumen of the inner ear membranous labyrinth. Its ionic composition is unique in vertebrates as an extracellular fluid for its high-K(+)/low-Na(+) concentration. The endolymph is actively secreted by specialized cells located in the vestibular and cochlear epithelia. We have investigated the early phases of endolymph secretion by measuring the endolymphatic K(+) concentration in the chicken vestibular system during pre-hatching development. Measurements were done by inserting K(+)-selective microelectrodes in chicken embryo ampullae dissected at different developmental stages from embryonic day 9 up to embryonic day 21 (day of hatching). We found that the K(+) concentration is low (<10mM/L) up to embryonic day 11, afterward it increases steeply to reach a plateau level of about 140 mM/L at embryonic day 19--21. We have developed a short-term in vitro model of endolymph secretion by culturing vestibular ampullae dissected from embryonic day 11 chicken embryos for a few days. The preparation reproduced a double compartment system where the luminal K(+) concentration increased along with the days of culturing. This model could be important for (1) investigating the development of cellular mechanisms contributing to endolymph homeostasis and (2) testing compounds that influence those mechanisms.

Impact of reionization on CMB polarization tests of slow-roll inflation

International Nuclear Information System (INIS)

Mortonson, Michael J.; Hu, Wayne

2008-01-01

Estimates of inflationary parameters from the CMB B-mode polarization spectrum on the largest scales depend on knowledge of the reionization history, especially at low tensor-to-scalar ratio. Assuming an incorrect reionization history in the analysis of such polarization data can strongly bias the inflationary parameters. One consequence is that the single-field slow-roll consistency relation between the tensor-to-scalar ratio and tensor tilt might be excluded with high significance even if this relation holds in reality. We explain the origin of the bias and present case studies with various tensor amplitudes and noise characteristics. A more model-independent approach can account for uncertainties about reionization, and we show that parametrizing the reionization history by a set of its principal components with respect to E-mode polarization removes the bias in inflationary parameter measurement with little degradation in precision

In vitro differentiation of mouse embryonic stem cells into functional ...

African Journals Online (AJOL)

Jane

2011-08-22

Aug 22, 2011 ... hepatocyte transplantation therapy and toxicity screening in drug discovery. Key words: Embryonic stem cells, hepatic-like cells, in vitro differentiation, sodium butyrate, ... from embryonic stem (ES) cell or induced pluripotent.

Probing Embryonic Stem Cell Autocrine and Paracrine Signaling Using Microfluidics

Science.gov (United States)

Przybyla, Laralynne; Voldman, Joel

2012-07-01

Although stem cell fate is traditionally manipulated by exogenously altering the cells' extracellular signaling environment, the endogenous autocrine and paracrine signals produced by the cells also contribute to their two essential processes: self-renewal and differentiation. Autocrine and/or paracrine signals are fundamental to both embryonic stem cell self-renewal and early embryonic development, but the nature and contributions of these signals are often difficult to fully define using conventional methods. Microfluidic techniques have been used to explore the effects of cell-secreted signals by controlling cell organization or by providing precise control over the spatial and temporal cellular microenvironment. Here we review how such techniques have begun to be adapted for use with embryonic stem cells, and we illustrate how many remaining questions in embryonic stem cell biology could be addressed using microfluidic technologies.

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First Planck results and cosmological implications

CERN Multimedia

CERN. Geneva

2013-01-01

The Planck satellite has measured CMB anisotropies over the full sky with unprecedented sensitivity. The collaboration has released its first CMB temperature maps and cosmological analysis on the 21st of March. I will present a summary of these new CMB results, focusing mainly on their implications for our understanding of the Universe.

Embryonic kidney function in a chronic renal failure model in rodents.

Science.gov (United States)

Fujimoto, Eisuke; Yamanaka, Shuichiro; Kurihara, Sho; Tajiri, Susumu; Izuhara, Luna; Katsuoka, Yuichi; Yokote, Shinya; Matsumoto, Kei; Kobayashi, Eiji; Okano, Hirotaka James; Chikaraishi, Tatsuya; Yokoo, Takashi

2017-08-01

Rapid advancements have been made in alternative treatments for renal diseases. Our goal for renal regeneration is to establish a kidney graft derived from human embryonic tissues. In this study, we investigated the effects of host renal failure on the structure and activity of transplanted embryonic kidney and bladder, and found that diuretics effectively induced urine production in the transplanted kidney. Uremic conditions were reproduced using a 5/6 renal infarction rat model. An embryonic kidney plus bladder (embryonic day 15) was isolated from a pregnant Lewis rat and transplanted into the para-aortic area of a 5/6 renal-infarcted Lewis rat. Following growth, the embryonic bladder was successfully anastomosed to the host ureter. We assessed graft function in terms of survival rates and found no differences between normal (n = 5) and renal failure (n = 8) groups (median survival: 70.5 vs 74.5 h; p = 0.331) in terms of survival, indicating that the grafts prolonged rat survival, even under renal failure conditions. Furosemide (n = 9) significantly increased urine volume compared with saline-treated controls (n = 7; p < 0.05), confirming that the grafts were functional. We also demonstrated the possibilities of an in vivo imaging system for determining the viability of transplanted embryonic kidney with bladder. The results of this study demonstrate that transplanted embryonic kidney and bladder can grow and function effectively, even under uremic conditions.

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Planck 2015 results: XI. CMB power spectra, likelihoods, and robustness of parameters

DEFF Research Database (Denmark)

Aghanim, N.; Arnaud, M.; Ashdown, M.

2016-01-01

on the same hybrid approach used for the previous release, i.e., a pixel-based likelihood at low multipoles (ℓ data and of Planck polarization......This paper presents the Planck 2015 likelihoods, statistical descriptions of the 2-point correlationfunctions of the cosmic microwave background (CMB) temperature and polarization fluctuations that account for relevant uncertainties, both instrumental and astrophysical in nature. They are based...... information, along with more detailed models of foregrounds and instrumental uncertainties. The increased redundancy brought by more than doubling the amount of data analysed enables further consistency checks and enhanced immunity to systematic effects. It also improves the constraining power of Planck...

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ACTPol: Status and preliminary CMB polarization results from the Atacama Cosmology Telescope

Science.gov (United States)

Koopman, Brian

2014-03-01

The Atacama Cosmology Telescope Polarimeter (ACTPol) is a polarization sensitive upgrade for the Atacama Cosmology Telescope, located at an elevation of 5190 m on Cerro Toco in Chile. In summer 2013, ACTPol achieved first light with one third of the final detector configuration. The remaining two thirds of the detector array will be installed during spring 2014, enabling full sensitivity, high resolution, observations at both 90 GHz and 150 GHz. Using approximately 3,000 transition-edge sensor bolometers, ACTPol will enable measurements of small angular scale polarization anisotropies in the Cosmic Microwave Background (CMB). I will present a status update for the ACTPol receiver and some preliminary results. ACTPol measurements will allow us to probe the spectral index of inflation as well as to constrain early dark energy and the sum of neutrino masses.

Effects of different feeder layers on culture of bovine embryonic stem cell-like cells in vitro.

Science.gov (United States)

Cong, Shan; Cao, Guifang; Liu, Dongjun

2014-12-01

To find a suitable feeder layer is important for successful culture conditions of bovine embryonic stem cell-like cells. In this study, expression of pluripotency-related genes OCT4, SOX2 and NANOG in bovine embryonic stem cell-like cells on mouse embryonic fibroblast feeder layers at 1-5 passages were monitored in order to identify the possible reason that bovine embryonic stem cell-like cells could not continue growth and passage. Here, we developed two novel feeder layers, mixed embryonic fibroblast feeder layers of mouse and bovine embryonic fibroblast at different ratios and sources including mouse fibroblast cell lines. The bovine embryonic stem cell-like cells generated in our study displayed typical stem cell morphology and expressed specific markers such as OCT4, stage-specific embryonic antigen 1 and 4, alkaline phosphatase, SOX2, and NANOG mRNA levels. When feeder layers and cell growth factors were removed, the bovine embryonic stem cell-like cells formed embryoid bodies in a suspension culture. Furthermore, we compared the expression of the pluripotent markers during bovine embryonic stem cell-like cell in culture on mixed embryonic fibroblast feeder layers, including mouse fibroblast cell lines feeder layers and mouse embryonic fibroblast feeder layers by real-time quantitative polymerase chain reaction. Results suggested that mixed embryonic fibroblast and sources including mouse fibroblast cell lines feeder layers were more suitable for long-term culture and growth of bovine embryonic stem cell-like cells than mouse embryonic fibroblast feeder layers. The findings may provide useful experimental data for the establishment of an appropriate culture system for bovine embryonic stem cell lines.

Recent discoveries from the cosmic microwave background: a review of recent progress

Science.gov (United States)

Staggs, Suzanne; Dunkley, Jo; Page, Lyman

2018-04-01

Measurements of the anisotropies in the cosmic microwave background (CMB) radiation have provided a wealth of information about the cosmological model that describes the contents and evolution of the universe. These data have led to a standard model described by just six parameters. In this review we focus on discoveries made in the past decade from satellite and ground-based experiments, and look ahead to those anticipated in the coming decade. We provide an introduction to the key CMB observables including temperature and polarization anisotropies, and describe recent progress towards understanding the initial conditions of structure formation, and establishing the properties of the contents of the universe including neutrinos. Results are now being derived both from the primordial CMB signal that traces the behavior of the universe at 400 000 years of cosmic time, as well as from the signals imprinted at later times due to scattering from galaxy clusters, from the motion of electrons in the ionized universe, and from the gravitational lensing of the CMB photons. We describe current experimental methods to measure the CMB, particularly focusing on details relevant for ground and balloon-based instruments, and give an overview of the broad data analysis methods required to convert measurements of the microwave sky into cosmological parameters.

Measurements of the Temperature and E-mode Polarization of the CMB from 500 Square Degrees of SPTpol Data

Science.gov (United States)

Henning, J. W.; Sayre, J. T.; Reichardt, C. L.; Ade, P. A. R.; Anderson, A. J.; Austermann, J. E.; Beall, J. A.; Bender, A. N.; Benson, B. A.; Bleem, L. E.; Carlstrom, J. E.; Chang, C. L.; Chiang, H. C.; Cho, H.-M.; Citron, R.; Corbett Moran, C.; Crawford, T. M.; Crites, A. T.; de Haan, T.; Dobbs, M. A.; Everett, W.; Gallicchio, J.; George, E. M.; Gilbert, A.; Halverson, N. W.; Harrington, N.; Hilton, G. C.; Holder, G. P.; Holzapfel, W. L.; Hoover, S.; Hou, Z.; Hrubes, J. D.; Huang, N.; Hubmayr, J.; Irwin, K. D.; Keisler, R.; Knox, L.; Lee, A. T.; Leitch, E. M.; Li, D.; Lowitz, A.; Manzotti, A.; McMahon, J. J.; Meyer, S. S.; Mocanu, L.; Montgomery, J.; Nadolski, A.; Natoli, T.; Nibarger, J. P.; Novosad, V.; Padin, S.; Pryke, C.; Ruhl, J. E.; Saliwanchik, B. R.; Schaffer, K. K.; Sievers, C.; Smecher, G.; Stark, A. A.; Story, K. T.; Tucker, C.; Vanderlinde, K.; Veach, T.; Vieira, J. D.; Wang, G.; Whitehorn, N.; Wu, W. L. K.; Yefremenko, V.

2018-01-01

We present measurements of the E-mode polarization angular auto-power spectrum (EE) and temperature–E-mode cross-power spectrum (TE) of the cosmic microwave background (CMB) using 150 GHz data from three seasons of SPTpol observations. We report the power spectra over the spherical harmonic multipole range 50 1050 and {\\ell }> 1475, respectively. The observations cover 500 {\\deg }2, a fivefold increase in area compared to previous SPTpol analyses, which increases our sensitivity to the photon diffusion damping tail of the CMB power spectra enabling tighter constraints on ΛCDM model extensions. After masking all sources with unpolarized flux > 50 mJy, we place a 95% confidence upper limit on residual polarized point-source power of {D}{\\ell }={\\ell }({\\ell }+1){C}{\\ell }/2π masking. We find that the SPTpol data set is in mild tension with the ΛCDM model (2.1σ ), and different data splits prefer parameter values that differ at the ∼ 1 σ level. When fitting SPTpol data at {\\ell }data at {\\ell }> 1000 results in a preference for a higher value of the expansion rate ({H}0=71.3+/- 2.1 {km} {{{s}}}-1{{Mpc}}-1 ) and a lower value for present-day density fluctuations ({σ }8=0.77+/- 0.02).

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Role of adiponectin in delayed embryonic development of the short-nosed fruit bat, Cynopterus sphinx.

Science.gov (United States)

Anuradha; Krishna, Amitabh

2014-12-01

The aim of this study was to evaluate the role of adiponectin in the delayed embryonic development of Cynopterus sphinx. Adiponectin receptor (ADIPOR1) abundance was first observed to be lower during the delayed versus non-delayed periods of utero-embryonic unit development. The effects of adiponectin treatment on embryonic development were then evaluated during the period of delayed development. Exogenous treatment increased the in vivo rate of embryonic development, as indicated by an increase in weight, ADIPOR1 levels in the utero-embryonic unit, and histological changes in embryonic development. Treatment with adiponectin during embryonic diapause showed a significant increase in circulating progesterone and estradiol concentrations, and in production of their receptors in the utero-embryonic unit. The adiponectin-induced increase in estradiol synthesis was correlated with increased cell survival (BCL2 protein levels) and cell proliferation (PCNA protein levels) in the utero-embryonic unit, suggesting an indirect effect of adiponectin via estradiol synthesis by the ovary. An in vitro study further confirmed the in vivo findings that adiponectin treatment increases PCNA levels together with increased uptake of glucose by increasing the abundance of glucose transporter 8 (GLUT8) in the utero-embryonic unit. The in vitro study also revealed that adiponectin, together with estradiol but not alone, significantly increased ADIPOR1 protein levels. Thus, adiponectin works in concert with estradiol to increase glucose transport to the utero-embryonic unit and promote cell proliferation, which together accelerate embryonic development. © 2014 Wiley Periodicals, Inc.

PTBP1 is required for embryonic development before gastrulation.

Science.gov (United States)

Suckale, Jakob; Wendling, Olivia; Masjkur, Jimmy; Jäger, Melanie; Münster, Carla; Anastassiadis, Konstantinos; Stewart, A Francis; Solimena, Michele

2011-02-17

Polypyrimidine-tract binding protein 1 (PTBP1) is an important cellular regulator of messenger RNAs influencing the alternative splicing profile of a cell as well as its mRNA stability, location and translation. In addition, it is diverted by some viruses to facilitate their replication. Here, we used a novel PTBP1 knockout mouse to analyse the tissue expression pattern of PTBP1 as well as the effect of its complete removal during development. We found evidence of strong PTBP1 expression in embryonic stem cells and throughout embryonic development, especially in the developing brain and spinal cord, the olfactory and auditory systems, the heart, the liver, the kidney, the brown fat and cartilage primordia. This widespread distribution points towards a role of PTBP1 during embryonic development. Homozygous offspring, identified by PCR and immunofluorescence, were able to implant but were arrested or retarded in growth. At day 7.5 of embryonic development (E7.5) the null mutants were about 5x smaller than the control littermates and the gap in body size widened with time. At mid-gestation, all homozygous embryos were resorbed/degraded. No homozygous mice were genotyped at E12 and the age of weaning. Embryos lacking PTBP1 did not display differentiation into the 3 germ layers and cavitation of the epiblast, which are hallmarks of gastrulation. In addition, homozygous mutants displayed malformed ectoplacental cones and yolk sacs, both early supportive structure of the embryo proper. We conclude that PTBP1 is not required for the earliest isovolumetric divisions and differentiation steps of the zygote up to the formation of the blastocyst. However, further post-implantation development requires PTBP1 and stalls in homozygous null animals with a phenotype of dramatically reduced size and aberration in embryonic and extra-embryonic structures.

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Interacting scalar tensor cosmology in light of SNeIa, CMB, BAO and OHD observational data sets

Energy Technology Data Exchange (ETDEWEB)

Rabiei, Sayed Wrya; Saaidi, Khaled [Faculty of Science University of Kurdistan, Department of Physics, Sanandaj (Iran, Islamic Republic of); Sheikhahmadi, Haidar [Faculty of Science University of Kurdistan, Department of Physics, Sanandaj (Iran, Islamic Republic of); Institute for Advance Studies in Basic Sciences (IASBS) Gava Zang, Zanjan (Iran, Islamic Republic of); Aghamohammadi, Ali [Sanandaj Branch Islamic Azad University, Sanandaj (Iran, Islamic Republic of)

2016-02-15

In this work, an interacting chameleon-like scalar field scenario, by considering SNeIa, CMB, BAO, and OHD data sets, is investigated. In fact, the investigation is realized by introducing an ansatz for the effective dark energy equation of state, which mimics the behavior of chameleon-like models. Based on this assumption, some cosmological parameters, including the Hubble, deceleration, and coincidence parameters, in such a mechanism are analyzed. It is realized that, to estimate the free parameters of a theoretical model, by regarding the systematic errors it is better that the whole of the above observational data sets would be considered. In fact, if one considers SNeIa, CMB, and BAO, but disregards OHD, it maybe leads to different results. Also, to get a better overlap between the contours with the constraint χ{sub m}{sup 2} ≤ 1, the χ{sub T}{sup 2} function could be re-weighted. The relative probability functions are plotted for marginalized likelihood L(Ω{sub m0}, ω{sub 1}, β) according to the two dimensional confidence levels 68.3, 90, and 95.4%. Meanwhile, the value of the free parameters which maximize the marginalized likelihoods using the above confidence levels are obtained. In addition, based on these calculations the minimum value of χ{sup 2} based on the free parameters of the ansatz for the effective dark energy equation of state is achieved. (orig.)

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A toolbox to explore the mechanics of living embryonic tissues

Science.gov (United States)

Campàs, Otger

2016-01-01

The sculpting of embryonic tissues and organs into their functional morphologies involves the spatial and temporal regulation of mechanics at cell and tissue scales. Decades of in vitro work, complemented by some in vivo studies, have shown the relevance of mechanical cues in the control of cell behaviors that are central to developmental processes, but the lack of methodologies enabling precise, quantitative measurements of mechanical cues in vivo have hindered our understanding of the role of mechanics in embryonic development. Several methodologies are starting to enable quantitative studies of mechanics in vivo and in situ, opening new avenues to explore how mechanics contributes to shaping embryonic tissues and how it affects cell behavior within developing embryos. Here we review the present methodologies to study the role of mechanics in living embryonic tissues, considering their strengths and drawbacks as well as the conditions in which they are most suitable. PMID:27061360

Melatonin regulates delayed embryonic development in the short-nosed fruit bat, Cynopterus sphinx.

Science.gov (United States)

Banerjee, Arnab; Meenakumari, K J; Udin, S; Krishna, A

2009-12-01

The aim of the present study was to evaluate the seasonal variation in serum melatonin levels and their relationship to the changes in the serum progesterone level, ovarian steroidogenesis, and embryonic development during two successive pregnancies of Cynopterus sphinx. Circulating melatonin concentrations showed two peaks; one coincided with the period of low progesterone synthesis and delayed embryonic development, whereas the second peak coincided with regressing corpus luteum. This finding suggests that increased serum melatonin level during November-December may be responsible for delayed embryonic development by suppressing progesterone synthesis. The study showed increased melatonin receptors (MTNR1A and MTNR1B) in the corpus luteum and in the utero-embryonic unit during the period of delayed embryonic development. The in vitro study showed that a high dose of melatonin suppressed progesterone synthesis, whereas a lower dose of melatonin increased progesterone synthesis by the ovary. The effects of melatonin on ovarian steroidogenesis are mediated through changes in the expression of peripheral-type benzodiazepine receptor, P450 side chain cleavage enzyme, and LH receptor proteins. This study further showed a suppressive impact of melatonin on the progesterone receptor (PGR) in the utero-embryonic unit; this effect might contribute to delayed embryonic development in C. sphinx. The results of the present study thus suggest that a high circulating melatonin level has a dual contribution in retarding embryonic development in C. sphinx by impairing progesterone synthesis as well as by inhibiting progesterone action by reducing expression of PGR in the utero-embryonic unit.

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Influx mechanisms in the embryonic and adult rat choroid plexus

DEFF Research Database (Denmark)

Saunders, Norman R; Dziegielewska, Katarzyna M; Møllgård, Kjeld

2015-01-01

The transcriptome of embryonic and adult rat lateral ventricular choroid plexus, using a combination of RNA-Sequencing and microarray data, was analyzed by functional groups of influx transporters, particularly solute carrier (SLC) transporters. RNA-Seq was performed at embryonic day (E) 15 and a...

Maternal Embryonic Leucine Zipper Kinase (MELK: A Novel Regulator in Cell Cycle Control, Embryonic Development, and Cancer

Directory of Open Access Journals (Sweden)

Pengfei Jiang

2013-10-01

Full Text Available Maternal embryonic leucine zipper kinase (MELK functions as a modulator of intracellular signaling and affects various cellular and biological processes, including cell cycle, cell proliferation, apoptosis, spliceosome assembly, gene expression, embryonic development, hematopoiesis, and oncogenesis. In these cellular processes, MELK functions by binding to numerous proteins. In general, the effects of multiple protein interactions with MELK are oncogenic in nature, and the overexpression of MELK in kinds of cancer provides some evidence that it may be involved in tumorigenic process. In this review, our current knowledge of MELK function and recent discoveries in MELK signaling pathway were discussed. The regulation of MELK in cancers and its potential as a therapeutic target were also described.

Precision Cosmology

Science.gov (United States)

Jones, Bernard J. T.

2017-04-01

Preface; Notation and conventions; Part I. 100 Years of Cosmology: 1. Emerging cosmology; 2. The cosmic expansion; 3. The cosmic microwave background; 4. Recent cosmology; Part II. Newtonian Cosmology: 5. Newtonian cosmology; 6. Dark energy cosmological models; 7. The early universe; 8. The inhomogeneous universe; 9. The inflationary universe; Part III. Relativistic Cosmology: 10. Minkowski space; 11. The energy momentum tensor; 12. General relativity; 13. Space-time geometry and calculus; 14. The Einstein field equations; 15. Solutions of the Einstein equations; 16. The Robertson-Walker solution; 17. Congruences, curvature and Raychaudhuri; 18. Observing and measuring the universe; Part IV. The Physics of Matter and Radiation: 19. Physics of the CMB radiation; 20. Recombination of the primeval plasma; 21. CMB polarisation; 22. CMB anisotropy; Part V. Precision Tools for Precision Cosmology: 23. Likelihood; 24. Frequentist hypothesis testing; 25. Statistical inference: Bayesian; 26. CMB data processing; 27. Parametrising the universe; 28. Precision cosmology; 29. Epilogue; Appendix A. SI, CGS and Planck units; Appendix B. Magnitudes and distances; Appendix C. Representing vectors and tensors; Appendix D. The electromagnetic field; Appendix E. Statistical distributions; Appendix F. Functions on a sphere; Appendix G. Acknowledgements; References; Index.

In vivo sensitivity of the embryonic and adult neural stem cell compartments to low-dose radiation.

Science.gov (United States)

Barazzuol, Lara; Jeggo, Penny A

2016-08-01

The embryonic brain is radiation-sensitive, with cognitive deficits being observed after exposure to low radiation doses. Exposure of neonates to radiation can cause intracranial carcinogenesis. To gain insight into the basis underlying these outcomes, we examined the response of the embryonic, neonatal and adult brain to low-dose radiation, focusing on the neural stem cell compartments. This review summarizes our recent findings. At E13.5-14.5 the embryonic neocortex encompasses rapidly proliferating stem and progenitor cells. Exploiting mice with a hypomorphic mutation in DNA ligase IV (Lig4(Y288C) ), we found a high level of DNA double-strand breaks (DSBs) at E14.5, which we attribute to the rapid proliferation. We observed endogenous apoptosis in Lig4(Y288C) embryos and in WT embryos following exposure to low radiation doses. An examination of DSB levels and apoptosis in adult neural stem cell compartments, the subventricular zone (SVZ) and the subgranular zone (SGZ) revealed low DSB levels in Lig4(Y288C) mice, comparable with the levels in differentiated neuronal tissues. We conclude that the adult SVZ does not incur high levels of DNA breakage, but sensitively activates apoptosis; apoptosis was less sensitively activated in the SGZ, and differentiated neuronal tissues did not activate apoptosis. P5/P15 mice showed intermediate DSB levels, suggesting that DSBs generated in the embryo can be transmitted to neonates and undergo slow repair. Interestingly, this analysis revealed a stage of high endogenous apoptosis in the neonatal SVZ. Collectively, these studies reveal that the adult neural stem cell compartment, like the embryonic counterpart, can sensitively activate apoptosis. © The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

Impact of nutritional stress on early embryonic survival

Directory of Open Access Journals (Sweden)

Sukanta Mondal

2015-09-01

Full Text Available Background: Low reproductive efficiency is the most critical problem faced by the livestock industry across the globe. Early embryonic loss is one the major cause of poor reproductive efficiency resulting in delayed pregnancy, fewer calves born, reduced milk production, slower genetic progress and substantial financial loss to the beef or dairy industry. The establishment of pregnancy results from the interaction between the embryo and the dam and is the culmination of a series of events initiated with development of the follicle and gametes. Among numerous internal and external factors nutrition has the potency to alter the micro-environment of the oocyte and the embryo, making it more hostile to optimal fertilization and pre-implantation embryonic growth. Understanding the impact of nutritional stress on oocyte function, embryo development and reciprocal signaling networks between the embryo and uterus will lead to alleviation of the problems of early embryonic mortality.

Chromatin in embryonic stem cell neuronal differentiation.

Science.gov (United States)

Meshorer, E

2007-03-01

Chromatin, the basic regulatory unit of the eukaryotic genetic material, is controlled by epigenetic mechanisms including histone modifications, histone variants, DNA methylation and chromatin remodeling. Cellular differentiation involves large changes in gene expression concomitant with alterations in genome organization and chromatin structure. Such changes are particularly evident in self-renewing pluripotent embryonic stem cells, which begin, in terms of cell fate, as a tabula rasa, and through the process of differentiation, acquire distinct identities. Here I describe the changes in chromatin that accompany neuronal differentiation, particularly of embryonic stem cells, and discuss how chromatin serves as the master regulator of cellular destiny.

Dark matter CMB constraints and likelihoods for poor particle physicists

Energy Technology Data Exchange (ETDEWEB)

Cline, James M.; Scott, Pat, E-mail: jcline@physics.mcgill.ca, E-mail: patscott@physics.mcgill.ca [Department of Physics, McGill University, 3600 rue University, Montréal, QC, H3A 2T8 (Canada)

2013-03-01

The cosmic microwave background provides constraints on the annihilation and decay of light dark matter at redshifts between 100 and 1000, the strength of which depends upon the fraction of energy ending up in the form of electrons and photons. The resulting constraints are usually presented for a limited selection of annihilation and decay channels. Here we provide constraints on the annihilation cross section and decay rate, at discrete values of the dark matter mass m{sub χ}, for all the annihilation and decay channels whose secondary spectra have been computed using PYTHIA in arXiv:1012.4515 (''PPPC 4 DM ID: a poor particle physicist cookbook for dark matter indirect detection''), namely e, μ, τ, V → e, V → μ, V → τ, u, d s, c, b, t, γ, g, W, Z and h. By interpolating in mass, these can be used to find the CMB constraints and likelihood functions from WMAP7 and Planck for a wide range of dark matter models, including those with annihilation or decay into a linear combination of different channels.

Dark matter CMB constraints and likelihoods for poor particle physicists

International Nuclear Information System (INIS)

Cline, James M.; Scott, Pat

2013-01-01

The cosmic microwave background provides constraints on the annihilation and decay of light dark matter at redshifts between 100 and 1000, the strength of which depends upon the fraction of energy ending up in the form of electrons and photons. The resulting constraints are usually presented for a limited selection of annihilation and decay channels. Here we provide constraints on the annihilation cross section and decay rate, at discrete values of the dark matter mass m χ , for all the annihilation and decay channels whose secondary spectra have been computed using PYTHIA in arXiv:1012.4515 (''PPPC 4 DM ID: a poor particle physicist cookbook for dark matter indirect detection''), namely e, μ, τ, V → e, V → μ, V → τ, u, d s, c, b, t, γ, g, W, Z and h. By interpolating in mass, these can be used to find the CMB constraints and likelihood functions from WMAP7 and Planck for a wide range of dark matter models, including those with annihilation or decay into a linear combination of different channels

The Extragalactic Background Light and the Gamma-ray Opacity of the Universe

Science.gov (United States)

Dwek, Eli; Krennrich, Frank

2012-01-01

The extragalactic background light (EBL) is one of the fundamental observational quantities in cosmology. All energy releases from resolved and unresolved extragalactic sources, and the light from any truly diffuse background, excluding the cosmic microwave background (CMB), contribute to its intensity and spectral energy distribution. It therefore plays a crucial role in cosmological tests for the formation and evolution of stellar objects and galaxies, and for setting limits on exotic energy releases in the universe. The EBL also plays an important role in the propagation of very high energy gamma-rays which are attenuated en route to Earth by pair producing gamma-gamma interactions with the EBL and CMB. The EBL affects the spectrum of the sources, predominantly blazars, in the approx 10 GeV to 10 TeV energy regime. Knowledge of the EBL intensity and spectrum will allow the determination of the intrinsic blazar spectrum in a crucial energy regime that can be used to test particle acceleration mechanisms and VHE gamma-ray production models. Conversely, knowledge of the intrinsic gamma-ray spectrum and the detection of blazars at increasingly higher redshifts will set strong limits on the EBL and its evolution. This paper reviews the latest developments in the determination of the EBL and its impact on the current understanding of the origin and production mechanisms of gamma-rays in blazars, and on energy releases in the universe. The review concludes with a summary and future directions in Cherenkov Telescope Array techniques and in infrared ground-based and space observatories that will greatly improve our knowledge of the EBL and the origin and production of very high energy gamma-rays.

Creation of quantized particles, gravitons, and scalar perturbations by the expanding universe

International Nuclear Information System (INIS)

Parker, Leonard

2015-01-01

Quantum creation processes during the very rapid early expansion of the universe are believed to give rise to temperature anisotropies and polarization patterns in the CMB radiation. These have been observed by satellites such as COBE, WMAP, and PLANCK, and by bolometric instruments placed near the South Pole by the BICEP collaborations. The expected temperature anisotropies are well-confirmed. The B-mode polarization patterns in the CMB are currently under measurement jointly by the PLANCK and BICEP groups to determine the extent to which the B-modes can be attributed to gravitational waves from the creation of gravitons in the earliest universe.As the original discoverer of the quantum phenomenon of particle creation from vacuum by the expansion of the universe, I will explain how the discovery came about and how it relates to the current observations. The first system that I considered when I started my Ph.D. thesis in 1962 was the quantized minimally-coupled scalar field in an expanding FLRW (Friedmann, Lemaitré, Robertson, Walker) universe having a general continuous scale factor a(t) with continuous time derivatives. I also considered quantized fermion fields of spin-1/2 and the spin-1 massless photon field, as well as the quantized conformally-invariant field equations of arbitrary integer and half-integer spins that had been written down in the classical context for general gravitational metrics by Penrose.It was during 1962 that I proved that quanta of the minimally-coupled scalar field were created by the general expanding FLRW universe. This was relevant also to the creation of quantized perturbations of the gravitational field, since these perturbations satisfied linear field equations that could be quantized in the same way as the minimally-coupled scalar field equation. In fact, in 1946, E.M. Lifshitz had considered the classical Einstein gravitational field in FLRW expanding universes and had shown that the classical linearized Einstein field

File list: InP.Emb.10.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Emb.50.AllAg.Embryonic_testis [Chip-atlas[Archive

Lifescience Database Archive (English)

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Effects of Exogenous Oxytocin on Embryonic Survival in Cows

Directory of Open Access Journals (Sweden)

A. Yildiz

2006-01-01

Full Text Available The aim of this study was to evaluate the effect of oxytocin on embryonic survival in dairy cows. Pregnancy was verified using the early pregnancy factor (EPF activity on Day 4 after artificial insemination (AI. Pregnant cows were randomly allotted to two groups: treated (n = 8 and control (n = 8. Oxytocin (100 IU, 5 ml, DIF Turkey was administered twice daily by intravenous injections to treated cows and sterile saline (5 ml to control cows immediately before milking on days 4 to 7 after AI. Blood samples were taken via jugular vein every day from day 4 to 8 and every other day until Day 20 following insemination to evaluate the effect of oxytocin on embryonic survival. The embryonic loss was diagnosed in 3 of the 8 cows treated with oxytocin, and embryonic survival rate was 62.5% in this group versus 87.5% in controls. Short cycles occurred in 37.5% of oxytocin-treated cows. At the same time their serum progesterone concentrations rose more slowly than in controls. It was concluded that cows administered oxytocin on days 4 to 7 after insemination are at a higher risk of pregnancy loss.

Constraining the shape of the CMB: A peak-by-peak analysis

International Nuclear Information System (INIS)

Oedman, Carolina J.; Hobson, Michael P.; Lasenby, Anthony N.; Melchiorri, Alessandro

2003-01-01

The recent measurements of the power spectrum of cosmic microwave background anisotropies are consistent with the simplest inflationary scenario and big bang nucleosynthesis constraints. However, these results rely on the assumption of a class of models based on primordial adiabatic perturbations, cold dark matter and a cosmological constant. In this paper we investigate the need for deviations from the Λ-CDM scenario by first characterizing the spectrum using a phenomenological function in a 15 dimensional parameter space. Using a Monte Carlo Markov chain approach to Bayesian inference and a low curvature model template we then check for the presence of new physics and/or systematics in the CMB data. We find an almost perfect consistency between the phenomenological fits and the standard Λ-CDM models. The curvature of the secondary peaks is weakly constrained by the present data, but they are well located. The improved spectral resolution expected from future satellite experiments is warranted for a definitive test of the scenario

File list: InP.Emb.50.AllAg.Embryonic_heart [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Emb.20.AllAg.Embryonic_heart [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Emb.05.AllAg.Embryonic_heart [Chip-atlas[Archive

Lifescience Database Archive (English)

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File list: InP.Emb.10.AllAg.Embryonic_heart [Chip-atlas[Archive

Lifescience Database Archive (English)

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Modeling the Radio Foreground for Detection of CMB Spectral Distortions from the Cosmic Dawn and the Epoch of Reionization

Energy Technology Data Exchange (ETDEWEB)

Sathyanarayana Rao, Mayuri; Subrahmanyan, Ravi; Shankar, N Udaya [Raman Research Institute, C V Raman Avenue, Sadashivanagar, Bangalore 560080 (India); Chluba, Jens, E-mail: mayuris@rri.res.in [Jodrell Bank Centre for Astrophysics, University of Manchester, Oxford Road, M13 9PL (United Kingdom)

2017-05-01

Cosmic baryon evolution during the Cosmic Dawn and Reionization results in redshifted 21-cm spectral distortions in the cosmic microwave background (CMB). These encode information about the nature and timing of first sources over redshifts 30–6 and appear at meter wavelengths as a tiny CMB distortion along with the Galactic and extragalactic radio sky, which is orders of magnitude brighter. Therefore, detection requires precise methods to model foregrounds. We present a method of foreground fitting using maximally smooth (MS) functions. We demonstrate the usefulness of MS functions over traditionally used polynomials to separate foregrounds from the Epoch of Reionization (EoR) signal. We also examine the level of spectral complexity in plausible foregrounds using GMOSS, a physically motivated model of the radio sky, and find that they are indeed smooth and can be modeled by MS functions to levels sufficient to discern the vanilla model of the EoR signal. We show that MS functions are loss resistant and robustly preserve EoR signal strength and turning points in the residuals. Finally, we demonstrate that in using a well-calibrated spectral radiometer and modeling foregrounds with MS functions, the global EoR signal can be detected with a Bayesian approach with 90% confidence in 10 minutes’ integration.

Measuring the Largest Angular Scale CMB B-mode Polarization with Galactic Foregrounds on a Cut Sky

Science.gov (United States)

Watts, Duncan J.; Larson, David; Marriage, Tobias A.; Abitbol, Maximilian H.; Appel, John W.; Bennett, Charles L.; Chuss, David T.; Eimer, Joseph R.; Essinger-Hileman, Thomas; Miller, Nathan J.; Rostem, Karwan; Wollack, Edward J.

2015-12-01

We consider the effectiveness of foreground cleaning in the recovery of Cosmic Microwave Background (CMB) polarization sourced by gravitational waves for tensor-to-scalar ratios in the range 0\\lt r\\lt 0.1. Using the planned survey area, frequency bands, and sensitivity of the Cosmology Large Angular Scale Surveyor (CLASS), we simulate maps of Stokes Q and U parameters at 40, 90, 150, and 220 GHz, including realistic models of the CMB, diffuse Galactic thermal dust and synchrotron foregrounds, and Gaussian white noise. We use linear combinations (LCs) of the simulated multifrequency data to obtain maximum likelihood estimates of r, the relative scalar amplitude s, and LC coefficients. We find that for 10,000 simulations of a CLASS-like experiment using only measurements of the reionization peak ({\\ell }≤slant 23), there is a 95% C.L. upper limit of r\\lt 0.017 in the case of no primordial gravitational waves. For simulations with r=0.01, we recover at 68% C.L. r={0.012}-0.006+0.011. The reionization peak corresponds to a fraction of the multipole moments probed by CLASS, and simulations including 30≤slant {\\ell }≤slant 100 further improve our upper limits to r\\lt 0.008 at 95% C.L. (r={0.010}-0.004+0.004 for primordial gravitational waves with r = 0.01). In addition to decreasing the current upper bound on r by an order of magnitude, these foreground-cleaned low multipole data will achieve a cosmic variance limited measurement of the E-mode polarization’s reionization peak.

GLUT3 gene expression is critical for embryonic growth, brain development and survival.

Science.gov (United States)

Carayannopoulos, Mary O; Xiong, Fuxia; Jensen, Penny; Rios-Galdamez, Yesenia; Huang, Haigen; Lin, Shuo; Devaskar, Sherin U

2014-04-01

Glucose is the primary energy source for eukaryotic cells and the predominant substrate for the brain. GLUT3 is essential for trans-placental glucose transport and highly expressed in the mammalian brain. To further elucidate the role of GLUT3 in embryonic development, we utilized the vertebrate whole animal model system of Danio rerio as a tractable system for defining the cellular and molecular mechanisms altered by impaired glucose transport and metabolism related to perturbed expression of GLUT3. The comparable orthologue of human GLUT3 was identified and the expression of this gene abrogated during early embryonic development. In a dose-dependent manner embryonic brain development was disrupted resulting in a phenotype of aberrant brain organogenesis, associated with embryonic growth restriction and increased cellular apoptosis. Rescue of the morphant phenotype was achieved by providing exogenous GLUT3 mRNA. We conclude that GLUT3 is critically important for brain organogenesis and embryonic growth. Disruption of GLUT3 is responsible for the phenotypic spectrum of embryonic growth restriction to demise and neural apoptosis with microcephaly. Copyright © 2014 Elsevier Inc. All rights reserved.

Galileon gravity in light of ISW, CMB, BAO and H {sub 0} data

Energy Technology Data Exchange (ETDEWEB)

Renk, Janina [The Oskar Klein Centre for Cosmoparticle Physics, Stockholm University, AlbaNova University Center, SE-106 91 Stockholm (Sweden); Zumalacárregui, Miguel [Nordita, KTH Royal Institute of Technology and Stockholm University, Roslagstullsbacken 23, SE-106 91 Stockholm (Sweden); Montanari, Francesco [Physics Department, University of Helsinki and Helsinki Institute of Physics, P.O. Box 64, 00014, University of Helsinki (Finland); Barreira, Alexandre, E-mail: janina.renk@fysik.su.se, E-mail: miguelzuma@berkeley.edu, E-mail: francesco.montanari@helsinki.fi, E-mail: barreira@mpa-garching.mpg.de [Max-Planck-Institut für Astrophysik, Karl-Schwarzschild-Str. 1, 85741 Garching (Germany)

2017-10-01

Cosmological models with Galileon gravity are an alternative to the standard ΛCDM paradigm with testable predictions at the level of its self-accelerating solutions for the expansion history, as well as large-scale structure formation. Here, we place constraints on the full parameter space of these models using data from the cosmic microwave background (CMB) (including lensing), baryonic acoustic oscillations (BAO) and the Integrated Sachs-Wolfe (ISW) effect. We pay special attention to the ISW effect for which we use the cross-spectra, C {sub ℓ}{sup Tg}, of CMB temperature maps and foreground galaxies from the WISE survey. The sign of C {sub ℓ}{sup Tg} is set by the time evolution of the lensing potential in the redshift range of the galaxy sample: it is positive if the potential decays (like in ΛCDM), negative if it deepens. We constrain three subsets of Galileon gravity separately known as the Cubic, Quartic and Quintic Galileons. The cubic Galileon model predicts a negative C {sub ℓ}{sup Tg} and exhibits a 7.8σ tension with the data, which effectively rules it out. For the quartic and quintic models the ISW data also rule out a significant portion of the parameter space but permit regions where the goodness-of-fit is comparable to ΛCDM. The data prefers a non zero sum of the neutrino masses (∑ m {sub ν} ≈ 0.5eV) with ∼ 5σ significance in these models. The best-fitting models have values of H {sub 0} consistent with local determinations, thereby avoiding the tension that exists in ΛCDM. We also identify and discuss a ∼ 2σ tension that Galileon gravity exhibits with recent BAO measurements. Our analysis shows overall that Galileon cosmologies cannot be ruled out by current data but future lensing, BAO and ISW data hold strong potential to do so.

Mechanical signaling coordinates the embryonic heartbeat

Science.gov (United States)

Chiou, Kevin K.; Rocks, Jason W.; Chen, Christina Yingxian; Cho, Sangkyun; Merkus, Koen E.; Rajaratnam, Anjali; Robison, Patrick; Tewari, Manorama; Vogel, Kenneth; Majkut, Stephanie F.; Prosser, Benjamin L.; Discher, Dennis E.; Liu, Andrea J.

2016-01-01

In the beating heart, cardiac myocytes (CMs) contract in a coordinated fashion, generating contractile wave fronts that propagate through the heart with each beat. Coordinating this wave front requires fast and robust signaling mechanisms between CMs. The primary signaling mechanism has long been identified as electrical: gap junctions conduct ions between CMs, triggering membrane depolarization, intracellular calcium release, and actomyosin contraction. In contrast, we propose here that, in the early embryonic heart tube, the signaling mechanism coordinating beats is mechanical rather than electrical. We present a simple biophysical model in which CMs are mechanically excitable inclusions embedded within the extracellular matrix (ECM), modeled as an elastic-fluid biphasic material. Our model predicts strong stiffness dependence in both the heartbeat velocity and strain in isolated hearts, as well as the strain for a hydrogel-cultured CM, in quantitative agreement with recent experiments. We challenge our model with experiments disrupting electrical conduction by perfusing intact adult and embryonic hearts with a gap junction blocker, β-glycyrrhetinic acid (BGA). We find this treatment causes rapid failure in adult hearts but not embryonic hearts—consistent with our hypothesis. Last, our model predicts a minimum matrix stiffness necessary to propagate a mechanically coordinated wave front. The predicted value is in accord with our stiffness measurements at the onset of beating, suggesting that mechanical signaling may initiate the very first heartbeats. PMID:27457951

Delayed embryonic development in the Indian short-nosed fruit bat, Cynopterus sphinx.

Science.gov (United States)

Meenakumari, Karukayil J; Krishna, Amitabh

2005-01-01

The unusual feature of the breeding cycle of Cynopterus sphinx at Varanasi is the significant variation in gestation length of the two successive pregnancies of the year. The aim of this study was to investigate whether the prolongation of the first pregnancy in C. sphinx is due to delayed embryonic development. The first (winter) pregnancy commences in late October and lasts until late March and has a gestation period of about 150 days. The second (summer) pregnancy commences in April and lasts until the end of July or early August with a gestation period of about 125 days. Changes in the size and weight of uterine cornua during the two successive pregnancies suggest retarded embryonic growth during November and December. Histological analysis during the period of retarded embryonic development in November and December showed a slow gastrulation process. The process of amniogenesis was particularly slow. When the embryos attained the early primitive streak stage, their developmental rate suddenly increased considerably. During the summer pregnancy, on the other hand, the process of gastrulation was much faster and proceeded quickly. A comparison of the pattern of embryonic development for 4 consecutive years consistently showed retarded or delayed embryonic development during November and December. The time of parturition and post-partum oestrus showed only a limited variation from 1 year to another. This suggests that delayed embryonic development in C. sphinx may function to synchronize parturition among females. The period of delayed embryonic development in this species clearly coincides with the period of fat deposition. The significance of this correlation warrants further investigation.

Constraints on hidden photons from current and future observations of CMB spectral distortions

International Nuclear Information System (INIS)

Kunze, Kerstin E.; Vázquez-Mozo, Miguel Á.

2015-01-01

A variety of beyond the standard model scenarios contain very light hidden sector U(1) gauge bosons undergoing kinetic mixing with the photon. The resulting oscillation between ordinary and hidden photons leads to spectral distortions of the cosmic microwave background. We update the bounds on the mixing parameter χ 0 and the mass of the hidden photon m γ' for future experiments measuring CMB spectral distortions, such as PIXIE and PRISM/COrE. For 10 −14  eV∼< m γ' ∼< 10 −13  eV, we find the kinetic mixing angle χ 0 has to be less than 10 −8 at 95% CL. These bounds are more than an order of magnitude stronger than those derived from the COBE/FIRAS data

Diploid, but not haploid, human embryonic stem cells can be derived from microsurgically repaired tripronuclear human zygotes

Science.gov (United States)

Fan, Yong; Li, Rong; Huang, Jin; Yu, Yang; Qiao, Jie

2013-01-01

Human embryonic stem cells have shown tremendous potential in regenerative medicine, and the recent progress in haploid embryonic stem cells provides new insights for future applications of embryonic stem cells. Disruption of normal fertilized embryos remains controversial; thus, the development of a new source for human embryonic stem cells is important for their usefulness. Here, we investigated the feasibility of haploid and diploid embryo reconstruction and embryonic stem cell derivation using microsurgically repaired tripronuclear human zygotes. Diploid and haploid zygotes were successfully reconstructed, but a large proportion of them still had a tripolar spindle assembly. The reconstructed embryos developed to the blastocyst stage, although the loss of chromosomes was observed in these zygotes. Finally, triploid and diploid human embryonic stem cells were derived from tripronuclear and reconstructed zygotes (from which only one pronucleus was removed), but haploid human embryonic stem cells were not successfully derived from the reconstructed zygotes when two pronuclei were removed. Both triploid and diploid human embryonic stem cells showed the general characteristics of human embryonic stem cells. These results indicate that the lower embryo quality resulting from abnormal spindle assembly contributed to the failure of the haploid embryonic stem cell derivation. However, the successful derivation of diploid embryonic stem cells demonstrated that microsurgical tripronuclear zygotes are an alternative source of human embryonic stem cells. In the future, improving spindle assembly will facilitate the application of triploid zygotes to the field of haploid embryonic stem cells. PMID:23255130

EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy

Directory of Open Access Journals (Sweden)

Mengtao Li

2016-03-01

Full Text Available Self-renewal and differentiation of neural stem cells is essential for embryonic neurogenesis, which is associated with cell autophagy. However, the mechanism by which autophagy regulates neurogenesis remains undefined. Here, we show that Eva1a/Tmem166, an autophagy-related gene, regulates neural stem cell self-renewal and differentiation. Eva1a depletion impaired the generation of newborn neurons, both in vivo and in vitro. Conversely, overexpression of EVA1A enhanced newborn neuron generation and maturation. Moreover, Eva1a depletion activated the PIK3CA-AKT axis, leading to the activation of the mammalian target of rapamycin and the subsequent inhibition of autophagy. Furthermore, addition of methylpyruvate to the culture during neural stem cell differentiation rescued the defective embryonic neurogenesis induced by Eva1a depletion, suggesting that energy availability is a significant factor in embryonic neurogenesis. Collectively, these data demonstrated that EVA1A regulates embryonic neurogenesis by modulating autophagy. Our results have potential implications for understanding the pathogenesis of neurodevelopmental disorders caused by autophagy dysregulation.

Case Study: Organotypic human in vitro models of embryonic morphogenetic fusion

Science.gov (United States)

Morphogenetic fusion of tissues is a common event in embryonic development and disruption of fusion is associated with birth defects of the eye, heart, neural tube, phallus, palate, and other organ systems. Embryonic tissue fusion requires precise regulation of cell-cell and cell...

Proteomic Analysis of Chicken Skeletal Muscle during Embryonic Development

Directory of Open Access Journals (Sweden)

Hongjia Ouyang

2017-05-01

Full Text Available Embryonic growth and development of skeletal muscle is a major determinant of muscle mass, and has a significant effect on meat production in chicken. To assess the protein expression profiles during embryonic skeletal muscle development, we performed a proteomics analysis using isobaric tags for relative and absolute quantification (iTRAQ in leg muscle tissues of female Xinghua chicken at embryonic age (E 11, E16, and 1-day post hatch (D1. We identified 3,240 proteins in chicken embryonic muscle and 491 of them were differentially expressed (fold change ≥ 1.5 or ≤ 0.666 and p < 0.05. There were 19 up- and 32 down-regulated proteins in E11 vs. E16 group, 238 up- and 227 down-regulated proteins in E11 vs. D1 group, and 13 up- and 5 down-regulated proteins in E16 vs. D1 group. Protein interaction network analyses indicated that these differentially expressed proteins were mainly involved in the pathway of protein synthesis, muscle contraction, and oxidative phosphorylation. Integrative analysis of proteome and our previous transcriptome data found 189 differentially expressed proteins that correlated with their mRNA level. The interactions between these proteins were also involved in muscle contraction and oxidative phosphorylation pathways. The lncRNA-protein interaction network found four proteins DMD, MYL3, TNNI2, and TNNT3 that are all involved in muscle contraction and may be lncRNA regulated. These results provide several candidate genes for further investigation into the molecular mechanisms of chicken embryonic muscle development, and enable us to better understanding their regulation networks and biochemical pathways.

Dynamic changes in energy metabolism upon embryonic stem cell differentiation support developmental toxicant identification

NARCIS (Netherlands)

Dartel, van D.A.M.; Schulpen, S.H.; Theunissen, P.T.; Bunschoten, A.; Piersma, A.H.; Keijer, J.

2014-01-01

Embryonic stem cells (ESC) are widely used to study embryonic development and to identify developmental toxicants. Particularly, the embryonic stem cell test (EST) is well known as in vitro model to identify developmental toxicants. Although it is clear that energy metabolism plays a crucial role in

Planck 2015 results. XI. CMB power spectra, likelihoods, and robustness of parameters

CERN Document Server

Aghanim, N.; Ashdown, M.; Aumont, J.; Baccigalupi, C.; Banday, A.J.; Barreiro, R.B.; Bartlett, J.G.; Bartolo, N.; Battaner, E.; Benabed, K.; Benoit, A.; Benoit-Levy, A.; Bernard, J.P.; Bersanelli, M.; Bielewicz, P.; Bock, J.J.; Bonaldi, A.; Bonavera, L.; Bond, J.R.; Borrill, J.; Bouchet, F.R.; Boulanger, F.; Bucher, M.; Burigana, C.; Butler, R.C.; Calabrese, E.; Cardoso, J.F.; Catalano, A.; Challinor, A.; Chiang, H.C.; Christensen, P.R.; Clements, D.L.; Colombo, L.P.L.; Combet, C.; Coulais, A.; Crill, B.P.; Curto, A.; Cuttaia, F.; Danese, L.; Davies, R.D.; Davis, R.J.; de Bernardis, P.; de Rosa, A.; de Zotti, G.; Delabrouille, J.; Desert, F.X.; Di Valentino, E.; Dickinson, C.; Diego, J.M.; Dolag, K.; Dole, H.; Donzelli, S.; Dore, O.; Douspis, M.; Ducout, A.; Dunkley, J.; Dupac, X.; Efstathiou, G.; Elsner, F.; Ensslin, T.A.; Eriksen, H.K.; Fergusson, J.; Finelli, F.; Forni, O.; Frailis, M.; Fraisse, A.A.; Franceschi, E.; Frejsel, A.; Galeotta, S.; Galli, S.; Ganga, K.; Gauthier, C.; Gerbino, M.; Giard, M.; Gjerlow, E.; Gonzalez-Nuevo, J.; Gorski, K.M.; Gratton, S.; Gregorio, A.; Gruppuso, A.; Gudmundsson, J.E.; Hamann, J.; Hansen, F.K.; Harrison, D.L.; Helou, G.; Henrot-Versille, S.; Hernandez-Monteagudo, C.; Herranz, D.; Hildebrandt, S.R.; Hivon, E.; Holmes, W.A.; Hornstrup, A.; Huffenberger, K.M.; Hurier, G.; Jaffe, A.H.; Jones, W.C.; Juvela, M.; Keihanen, E.; Keskitalo, R.; Kiiveri, K.; Knoche, J.; Knox, L.; Kunz, M.; Kurki-Suonio, H.; Lagache, G.; Lahteenmaki, A.; Lamarre, J.M.; Lasenby, A.; Lattanzi, M.; Lawrence, C.R.; Le Jeune, M.; Leonardi, R.; Lesgourgues, J.; Levrier, F.; Lewis, A.; Liguori, M.; Lilje, P.B.; Lilley, M.; Linden-Vornle, M.; Lindholm, V.; Lopez-Caniego, M.; Macias-Perez, J.F.; Maffei, B.; Maggio, G.; Maino, D.; Mandolesi, N.; Mangilli, A.; Maris, M.; Martin, P.G.; Martinez-Gonzalez, E.; Masi, S.; Matarrese, S.; Meinhold, P.R.; Melchiorri, A.; Migliaccio, M.; Millea, M.; Miville-Deschenes, M.A.; Moneti, A.; Montier, L.; Morgante, G.; Mortlock, D.; Munshi, D.; Murphy, J.A.; Narimani, A.; Naselsky, P.; Nati, F.; Natoli, P.; Noviello, F.; Novikov, D.; Novikov, I.; Oxborrow, C.A.; Paci, F.; Pagano, L.; Pajot, F.; Paoletti, D.; Partridge, B.; Pasian, F.; Patanchon, G.; Pearson, T.J.; Perdereau, O.; Perotto, L.; Pettorino, V.; Piacentini, F.; Piat, M.; Pierpaoli, E.; Pietrobon, D.; Plaszczynski, S.; Pointecouteau, E.; Polenta, G.; Ponthieu, N.; Pratt, G.W.; Prunet, S.; Puget, J.L.; Rachen, J.P.; Reinecke, M.; Remazeilles, M.; Renault, C.; Renzi, A.; Ristorcelli, I.; Rocha, G.; Rossetti, M.; Roudier, G.; d'Orfeuil, B.Rouille; Rubino-Martin, J.A.; Rusholme, B.; Salvati, L.; Sandri, M.; Santos, D.; Savelainen, M.; Savini, G.; Scott, D.; Serra, P.; Spencer, L.D.; Spinelli, M.; Stolyarov, V.; Stompor, R.; Sunyaev, R.; Sutton, D.; Suur-Uski, A.S.; Sygnet, J.F.; Tauber, J.A.; Terenzi, L.; Toffolatti, L.; Tomasi, M.; Tristram, M.; Trombetti, T.; Tucci, M.; Tuovinen, J.; Umana, G.; Valenziano, L.; Valiviita, J.; Van Tent, B.; Vielva, P.; Villa, F.; Wade, L.A.; Wandelt, B.D.; Wehus, I.K.; Yvon, D.; Zacchei, A.; Zonca, A.

2016-01-01

This paper presents the Planck 2015 likelihoods, statistical descriptions of the 2-point correlation functions of CMB temperature and polarization. They use the hybrid approach employed previously: pixel-based at low multipoles, $\\ell$, and a Gaussian approximation to the distribution of cross-power spectra at higher $\\ell$. The main improvements are the use of more and better processed data and of Planck polarization data, and more detailed foreground and instrumental models. More than doubling the data allows further checks and enhanced immunity to systematics. Progress in foreground modelling enables a larger sky fraction, contributing to enhanced precision. Improvements in processing and instrumental models further reduce uncertainties. Extensive tests establish robustness and accuracy, from temperature, from polarization, and from their combination, and show that the {\\Lambda}CDM model continues to offer a very good fit. We further validate the likelihood against specific extensions to this baseline, suc...

A Guide to Designing Future Ground-based CMB Experiments

International Nuclear Information System (INIS)

Wu, W. L.K.; Errard, J.; Dvorkin, C.; Kuo, C. L.; Lee, A. T.; McDonald, P.; Slosar, A.; Zahn, O.

2014-01-01

In this follow-up work to the High Energy Physics Community Summer Study 2013 (HEP CSS 2013, a.k.a. Snowmass), we explore the scientific capabilities of a future Stage-IV Cosmic Microwave Background polarization experiment (CMB-S4) under various assumptions on detector count, resolution, and sky coverage. We use the Fisher matrix technique to calculate the expected uncertainties in cosmological parameters in vΛCDM that are especially relevant to the physics of fundamental interactions, including neutrino masses, effective number of relativistic species, dark-energy equation of state, dark-matter annihilation, and inflationary parameters. To further chart the landscape of future cosmology probes, we include forecasted results from the Baryon Acoustic Oscillation (BAO) signal as measured by DESI to constrain parameters that would benefit from low redshift information. We find the following best 1-δ constraints: δ(M_v ) = 15 meV, δ(N_e_f_f ) = 0.0156, Dark energy Figure of Merit = 303, δ(p_a_n_n) = 0.00588 x 3 x 10"-"2"6 cm"3/s/GeV, δ(Ω_K) = 0.00074, δ(n_s) = 0.00110, δ(α_s) = 0.00145, and δ(r) = 0.00009. We also detail the dependences of the parameter constraints on detector count, resolution, and sky coverage.

G-quadruplexes as novel cis-elements controlling transcription during embryonic development.

Science.gov (United States)

David, Aldana P; Margarit, Ezequiel; Domizi, Pablo; Banchio, Claudia; Armas, Pablo; Calcaterra, Nora B

2016-05-19

G-quadruplexes are dynamic structures folded in G-rich single-stranded DNA regions. These structures have been recognized as a potential nucleic acid based mechanism for regulating multiple cellular processes such as replication, transcription and genomic maintenance. So far, their transcriptional role in vivo during vertebrate embryonic development has not yet been addressed. Here, we performed an in silico search to find conserved putative G-quadruplex sequences (PQSs) within proximal promoter regions of human, mouse and zebrafish developmental genes. Among the PQSs able to fold in vitro as G-quadruplex, those present in nog3, col2a1 and fzd5 promoters were selected for further studies. In cellulo studies revealed that the selected G-quadruplexes affected the transcription of luciferase controlled by the SV40 nonrelated promoter. G-quadruplex disruption in vivo by microinjection in zebrafish embryos of either small ligands or DNA oligonucleotides complementary to the selected PQSs resulted in lower transcription of the targeted genes. Moreover, zebrafish embryos and larvae phenotypes caused by the presence of complementary oligonucleotides fully resembled those ones reported for nog3, col2a1 and fzd5 morphants. To our knowledge, this is the first work revealing in vivo the role of conserved G-quadruplexes in the embryonic development, one of the most regulated processes of the vertebrates biology. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

The hot Hagedorn Universe. Presented at the ICFNP2015 meeting, August 2015

Directory of Open Access Journals (Sweden)

Rafelski Johann

2016-01-01

Full Text Available In the context of the half-centenary of Hagedorn temperature and the statistical bootstrap model (SBM we present a short account of how these insights coincided with the establishment of the hot big-bang model (BBM and helped resolve some of the early philosophical difficulties. We then turn attention to the present day context and show the dominance of strong interaction quark and gluon degrees of freedom in the early stage, helping to characterize the properties of the hot Universe. We focus attention on the current experimental insights about cosmic microwave background (CMB temperature fluctuation, and develop a much improved understanding of the neutrino freeze-out, in this way paving the path to the opening of a direct connection of quark-gluon plasma (QGP physics in the early Universe with the QCD-lattice, and the study of the properties of QGP formed in the laboratory.

Effect of gamma irradiation on the hatchability and embryonic development of quail eggs

International Nuclear Information System (INIS)

Oroszlany, P.; Sinkovicsne Hlubik, I.

1979-01-01

The effect of different doses of gamma irradiation on the embryonic development of quail and hen's eggs was examined. The goals of the examinations were to determine the LD 50 and LD 100 values, to establish the effect of single and multiple irradiation on embryonic development and to get some information on the embryonation of eggs produced by quails and their progeny grown from irradiated eggs. It was shown that 200 rad dose has significant stimulation effect of the hatching results of quail eggs. The LD 50 and LD 100 values were about 800 to 850 rad and 1600 rad, respectively. Repeated irradiation on the progeny-generations proved to be unambiguously deleterious on embryonation. High doses changed the rhythm of embryonal mortality, showing a peak under the irradiation and in the first three days of incubation, and significantly enhanced the number of teratological types. (author)

Atacama Cosmology Telescope: Polarization calibration analysis for CMB measurements with ACTPol and Advanced ACTPol

Science.gov (United States)

Koopman, Brian; ACTPol Collaboration

2015-04-01

The Atacama Cosmology Telescope Polarimeter (ACTPol) is a polarization sensitive upgrade for the Atacama Cosmology Telescope, located at an elevation of 5190 m on Cerro Toco in Chile. Achieving first light in 2013, ACTPol is entering its third observation season. Advanced ACTPol is a next generation upgrade for ACTPol, with additional frequencies, polarization modulation, and new detector arrays, that will begin in 2016. I will first present an overview of the two projects and then focus on describing the methods used for polarization angle calibration of the ACTPol detectors. These methods utilize polarization ray tracing in the optical design software CODEV together with detector positions determined from planet observations and represent a critical input for mapping the polarization of the CMB.

Effects of different feeder layers on culture of bovine embryonic stem cell-like cells in vitro

OpenAIRE

Cong, Shan; Cao, Guifang; Liu, Dongjun

2014-01-01

To find a suitable feeder layer is important for successful culture conditions of bovine embryonic stem cell-like cells. In this study, expression of pluripotency-related genes OCT4, SOX2 and NANOG in bovine embryonic stem cell-like cells on mouse embryonic fibroblast feeder layers at 1–5 passages were monitored in order to identify the possible reason that bovine embryonic stem cell-like cells could not continue growth and passage. Here, we developed two novel feeder layers, mixed embryonic ...

Mouse Embryonic Stem Cell Adherent Cell Differentiation and Cytotoxicity (ACDC) assay

Science.gov (United States)

The Embryonic Stem Cell Test (EST) is an assay which evaluates xenobiotic-induced effects using three endpoints: mouse embryonic stem cell (mESC) differentiation, mESC viability, and 3T3-cell viability. Our research goal was to develop an improved high-throughput assay by establi...

Do embryonic polar bodies commit suicide?

Science.gov (United States)

Fabian, Dušan; Čikoš, Štefan; Rehák, Pavol; Koppel, Juraj

2014-02-01

The extrusion and elimination of unnecessary gametic/embryonic material is one of the key events that determines the success of further development in all living organisms. Oocytes produce the first polar body to fulfill the maturation process just before ovulation, and release the second polar body immediately after fertilization. The aim of this study was to compile a physiological overview of elimination of polar bodies during early preimplantation development in mice. Our results show that three-quarters of the first polar bodies were lost even at the zygotic stage; the 4-cell stage embryos contained only one (second) polar body, and the elimination of second polar bodies proceeded continuously during later development. Both first and second polar bodies showed several typical features of apoptosis: phosphatidylserine redistribution (observed for the first time in the first polar body), specific DNA degradation, condensed nuclear morphology, and inability to exclude cationic dye from the nucleus during the terminal stage of the apoptotic process. Caspase-3 activity was recorded only in the second polar body. From the morphological point of view, mouse polar bodies acted very similarly to damaged embryonic cells which have lost contact with their neighboring blastomeres. In conclusion, polar bodies possess all the molecular equipment necessary for triggering and executing an active suicide process. Furthermore, similarly as in dying embryonic cells, stressing external conditions (culture in vitro) might accelerate and increase the incidence of apoptotic elimination of the polar bodies in embryos.

Physics Colloquium | 25 February

CERN Multimedia

2013-01-01

Critical Tests of Theory of the Early Universe using the Cosmic Microwave Background, by Prof. Eiichiro Komatsu, Max-Planck-Institut für Astrophysik, Garching, (Germany). Monday 25 February 2013 at 17:00 École de Physique, Auditoire Stueckelberg 24, quai Ernest-Ansermet, 1211 Genève 4 Abstract: The Cosmic Microwave Background (CMB), the fossil light of the Big Bang, is the oldest light that one can ever hope to observe in our Universe. The CMB provides us with a direct image of the Universe when it was still an "infant" - 380,000 years old. The Wilkinson Microwave Anisotropy Probe (WMAP) has mapped the microwave sky in five frequency bands for nine years since 2001, creating a full-sky CMB map with the unprecedented precision. The WMAP data have enabled us to obtain a wealth of cosmological information, such as the composition, age, geometry, and history of the Universe. Yet, can we go further and learn about the primordial universe, when it was much younge...

Cytokine signalling in embryonic stem cells

DEFF Research Database (Denmark)

Kristensen, David Møbjerg; Kalisz, Mark; Nielsen, Jens Høiriis

2006-01-01

Cytokines play a central role in maintaining self-renewal in mouse embryonic stem (ES) cells through a member of the interleukin-6 type cytokine family termed leukemia inhibitory factor (LIF). LIF activates the JAK-STAT3 pathway through the class I cytokine receptor gp130, which forms a trimeric...... pathways seem to converge on c-myc as a common target to promote self-renewal. Whereas LIF does not seem to stimulate self-renewal in human embryonic stem cells it cannot be excluded that other cytokines are involved. The pleiotropic actions of the increasing number of cytokines and receptors signalling...... via JAKs, STATs and SOCS exhibit considerable redundancy, compensation and plasticity in stem cells in accordance with the view that stem cells are governed by quantitative variations in strength and duration of signalling events known from other cell types rather than qualitatively different stem...

Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes

Science.gov (United States)

Fang, Xiefan; Mei, Wenbin; Barbazuk, William B.; Rivkees, Scott A.

2014-01-01

Previous studies demonstrated that in utero caffeine treatment at embryonic day (E) 8.5 alters DNA methylation patterns, gene expression, and cardiac function in adult mice. To provide insight into the mechanisms, we examined cardiac gene and microRNA (miRNA) expression in cardiomyocytes shortly after exposure to physiologically relevant doses of caffeine. In HL-1 and primary embryonic cardiomyocytes, caffeine treatment for 48 h significantly altered the expression of cardiac structural genes (Myh6, Myh7, Myh7b, Tnni3), hormonal genes (Anp and BnP), cardiac transcription factors (Gata4, Mef2c, Mef2d, Nfatc1), and microRNAs (miRNAs; miR208a, miR208b, miR499). In addition, expressions of these genes were significantly altered in embryonic hearts exposed to in utero caffeine. For in utero experiments, pregnant CD-1 dams were treated with 20–60 mg/kg of caffeine, which resulted in maternal circulation levels of 37.3–65.3 μM 2 h after treatment. RNA sequencing was performed on embryonic ventricles treated with vehicle or 20 mg/kg of caffeine daily from E6.5-9.5. Differential expression (DE) analysis revealed that 124 genes and 849 transcripts were significantly altered, and differential exon usage (DEU) analysis identified 597 exons that were changed in response to prenatal caffeine exposure. Among the DE genes identified by RNA sequencing were several cardiac structural genes and genes that control DNA methylation and histone modification. Pathway analysis revealed that pathways related to cardiovascular development and diseases were significantly affected by caffeine. In addition, global cardiac DNA methylation was reduced in caffeine-treated cardiomyocytes. Collectively, these data demonstrate that caffeine exposure alters gene expression and DNA methylation in embryonic cardiomyocytes. PMID:25354728

Intact calcium signaling in adrenergic-deficient embryonic mouse hearts.

Science.gov (United States)

Peoples, Jessica N; Taylor, David G; Katchman, Alexander N; Ebert, Steven N

2018-01-22

Mouse embryos that lack the ability to produce the adrenergic hormones, norepinephrine (NE) and epinephrine (EPI), due to disruption of the dopamine beta-hydroxylase (Dbh -/- ) gene inevitably perish from heart failure during mid-gestation. Since adrenergic stimulation is well-known to enhance calcium signaling in developing as well as adult myocardium, and impairments in calcium signaling are typically associated with heart failure, we hypothesized that adrenergic-deficient embryonic hearts would display deficiencies in cardiac calcium signaling relative to adrenergic-competent controls at a developmental stage immediately preceding the onset of heart failure, which first appears beginning or shortly after mouse embryonic day 10.5 (E10.5). To test this hypothesis, we used ratiometric fluorescent calcium imaging techniques to measure cytosolic calcium transients, [Ca 2+ ] i in isolated E10.5 mouse hearts. Our results show that spontaneous [Ca 2+ ] i oscillations were intact and robustly responded to a variety of stimuli including extracellular calcium (5 mM), caffeine (5 mM), and NE (100 nM) in a manner that was indistinguishable from controls. Further, we show similar patterns of distribution (via immunofluorescent histochemical staining) and activity (via patch-clamp recording techniques) for the major voltage-gated plasma membrane calcium channel responsible for the L-type calcium current, I Ca,L , in adrenergic-deficient and control embryonic cardiac cells. These results demonstrate that despite the absence of vital adrenergic hormones that consistently leads to embryonic lethality in vivo, intracellular and extracellular calcium signaling remain essentially intact and functional in embryonic mouse hearts through E10.5. These findings suggest that adrenergic stimulation is not required for the development of intracellular calcium oscillations or extracellular calcium signaling through I Ca,L and that aberrant calcium signaling does not likely contribute

Carcino-Embryonic Antigen

International Nuclear Information System (INIS)

Akute, O.

1999-02-01

Tumour marker analysis has increased our understanding of the presence of tumours in the body. Carcino-embryonic antigen, CEA, is one of the best studied tumour markers and has proved an ideal diagnostic adjuvant. It has helped in quantifying the amount of disease present in a patient and thence to make accurate prognosis on the various diagnosed ailments. At UCH, it is observed that there is an increase in cancer related ailments and therefore the need for early diagnosis is more compelling in our environment to mitigate future cost of managing advanced manifestation

Low oxygen levels slow embryonic development of Limulus polyphemus

DEFF Research Database (Denmark)

Funch, Peter; Wang, Tobias; Pertoldi, Cino

2016-01-01

The American horseshoe crab Limulus polyphemus typically spawns in the upper intertidal zone, where the developing embryos are exposed to large variations in abiotic factors such as temperature, humidity, salinity, and oxygen, which affect the rate of development. It has been shown that embryonic...... pronounced hypoxia in later embryonic developmental stages, but also in earlier, previously unexplored, developmental stages....... development is slowed at both high and low salinities and temperatures, and that late embryos close to hatching tolerate periodic hypoxia. In this study we investigated the influence of hypoxia on both early and late embryonic development in L. polyphemus under controlled laboratory conditions. Embryos were...

The Cosmology Large Angular Scale Surveyor (CLASS) Telescope Architecture

Science.gov (United States)

Chuss, David T.; Ali, Aamir; Amiri, Mandana; Appel, John W.; Araujo, Derek; Bennett, Charles L.; Boone, Fletcher; Chan, Manwei; Cho, Hsiao-Mei; Colazo, Felipe;

Protective effects of resveratrol on ethanol-induced apoptosis in embryonic stem cells and disruption of embryonic development in mouse blastocysts

International Nuclear Information System (INIS)

Huang, L.-H.; Shiao, N.-H.; Hsuuw, Y.-D.; Chan, W.-H.

2007-01-01

Previous studies have established that ethanol induces apoptosis, but the precise molecular mechanisms are currently unclear. Here, we show that 0.3-1.0% (w/v) ethanol induces apoptosis in mouse blastocysts and that resveratrol, a grape-derived phytoalexin with known antioxidant and anti-inflammatory properties, prevents ethanol-induced apoptosis and inhibition of cell proliferation. Moreover, ethanol-treated blastocysts show normal levels of implantation on culture dishes in vitro but a reduced ability to reach the later stages of embryonic development. Pretreatment with resveratrol prevented ethanol-induced disruption of embryonic development in vitro and in vivo. In an in vitro cell-based assay, we further found that ethanol increases the production of reactive oxygen species in ESC-B5 embryonic stem cells, leading to an increase in the intracellular concentrations of cytoplasmic free Ca 2+ and NO, loss of mitochondrial membrane potential, mitochondrial release of cytochrome c, activation of caspase-9 and -3, and apoptosis. These changes were blocked by pretreatment with resveratrol. Based on these results, we propose a model for the protective effect of resveratrol on ethanol-induced cell injury in blastocysts and ESC-B5 cells

An anisotropic universe due to dimension-changing vacuum decay

International Nuclear Information System (INIS)

Scargill, James H.C.

2015-01-01

In this paper we consider the question of observational signatures of a false vacuum decay event in the early universe followed by a period of inflation; in particular, motivated by the string landscape, we consider decays in which the parent vacuum has a smaller number of large dimensions than the current vacuum, which leads to an anisotropic universe. We go beyond previous studies, and examine the effects on the CMB temperature and polarisation power spectra, due to both scalar and tensor modes, and consider not only late-time effects but also the full cosmological perturbation theory at early times. We find that whilst the scalar mode behaves as one would expect, and the effects of anisotropy at early times are sub-dominant to the late-time effects already studied, for the tensor modes in fact the the early-time effects grow with multipole and can become much larger than one would expect, even dominating over the late-time effects. Thus these effects should be included if one is looking for such a signal in the tensor modes

Human Embryonic Stem Cell Therapy in Crohn’s Disease: A Case Report

Science.gov (United States)

Shroff, Geeta

2016-01-01

Patient: Male, 21 Final Diagnosis: Crohn’s disease Symptoms: Intolerance to specific foods • abdominal pain and diarrhea Medication: Human embryonic stem cell therapy Clinical Procedure: Human embryonic stem cell transplantation Specialty: Gastroenterology Objective: Unusual or unexpected effect of treatment Background: Crohn’s disease is a chronic inflammatory disease of the intestines, mainly the colon and ileum, related with ulcers and fistulae. It is estimated to affect 565 000 people in the United States. Currently available therapies, such as antibiotics, thiopurines, and anti-tumor necrosis factor-alpha agents, are only observed to reduce the complications associated with Crohn’s disease and to improve quality of life, but cannot cure the disease. Stem cell therapy appears to have certain advantages over conventional therapies. Our study aimed to evaluate the efficacy of human embryonic stem cell therapy in a patient with Crohn’s disease. Case Report: A 21-year-old male with chief complaints of intolerance to specific foods, abdominal pain, and diarrhea underwent human embryonic stem cell therapy for two months. After undergoing human embryonic stem cell therapy, the patient showed symptomatic relief. He had no complaints of back pain, abdominal pain, or diarrhea and had improved digestion. The patient had no signs and symptoms of skin infection, and had improved limb stamina, strength, and endurance. The condition of patient was stable after the therapy. Conclusions: Human embryonic stem cell therapy might serve as a new optimistic treatment approach for Crohn’s disease. PMID:26923312

Nitric oxide synthase-3 promotes embryonic development of atrioventricular valves.

Directory of Open Access Journals (Sweden)

Yin Liu

Full Text Available Nitric oxide synthase-3 (NOS3 has recently been shown to promote endothelial-to-mesenchymal transition (EndMT in the developing atrioventricular (AV canal. The present study was aimed to investigate the role of NOS3 in embryonic development of AV valves. We hypothesized that NOS3 promotes embryonic development of AV valves via EndMT. To test this hypothesis, morphological and functional analysis of AV valves were performed in wild-type (WT and NOS3(-/- mice at postnatal day 0. Our data show that the overall size and length of mitral and tricuspid valves were decreased in NOS3(-/- compared with WT mice. Echocardiographic assessment showed significant regurgitation of mitral and tricuspid valves during systole in NOS3(-/- mice. These phenotypes were all rescued by cardiac specific NOS3 overexpression. To assess EndMT, immunostaining of Snail1 was performed in the embryonic heart. Both total mesenchymal and Snail1(+ cells in the AV cushion were decreased in NOS3(-/- compared with WT mice at E10.5 and E12.5, which was completely restored by cardiac specific NOS3 overexpression. In cultured embryonic hearts, NOS3 promoted transforming growth factor (TGFβ, bone morphogenetic protein (BMP2 and Snail1expression through cGMP. Furthermore, mesenchymal cell formation and migration from cultured AV cushion explants were decreased in the NOS3(-/- compared with WT mice. We conclude that NOS3 promotes AV valve formation during embryonic heart development and deficiency in NOS3 results in AV valve insufficiency.

Use of deep neural network ensembles to identify embryonic-fetal transition markers: repression of COX7A1 in embryonic and cancer cells.

Science.gov (United States)

West, Michael D; Labat, Ivan; Sternberg, Hal; Larocca, Dana; Nasonkin, Igor; Chapman, Karen B; Singh, Ratnesh; Makarev, Eugene; Aliper, Alex; Kazennov, Andrey; Alekseenko, Andrey; Shuvalov, Nikolai; Cheskidova, Evgenia; Alekseev, Aleksandr; Artemov, Artem; Putin, Evgeny; Mamoshina, Polina; Pryanichnikov, Nikita; Larocca, Jacob; Copeland, Karen; Izumchenko, Evgeny; Korzinkin, Mikhail; Zhavoronkov, Alex

2018-01-30

Here we present the application of deep neural network (DNN) ensembles trained on transcriptomic data to identify the novel markers associated with the mammalian embryonic-fetal transition (EFT). Molecular markers of this process could provide important insights into regulatory mechanisms of normal development, epimorphic tissue regeneration and cancer. Subsequent analysis of the most significant genes behind the DNNs classifier on an independent dataset of adult-derived and human embryonic stem cell (hESC)-derived progenitor cell lines led to the identification of COX7A1 gene as a potential EFT marker. COX7A1 , encoding a cytochrome C oxidase subunit, was up-regulated in post-EFT murine and human cells including adult stem cells, but was not expressed in pre-EFT pluripotent embryonic stem cells or their in vitro -derived progeny. COX7A1 expression level was observed to be undetectable or low in multiple sarcoma and carcinoma cell lines as compared to normal controls. The knockout of the gene in mice led to a marked glycolytic shift reminiscent of the Warburg effect that occurs in cancer cells. The DNN approach facilitated the elucidation of a potentially new biomarker of cancer and pre-EFT cells, the embryo-onco phenotype, which may potentially be used as a target for controlling the embryonic-fetal transition.

Medical student retention of embryonic development: impact of the dimensions added by multimedia tutorials.

Science.gov (United States)

Marsh, Karen R; Giffin, Bruce F; Lowrie, Donald J

2008-01-01

The purpose of this project was to develop Web-based learning modules that combine (1) animated 3D graphics; (2) 3D models that a student can manipulate independently; (3) passage of time in embryonic development; and (4) animated 2D graphics, including 2D cross-sections that represent different "slices" of the embryo, and animate in parallel. These elements were presented in two tutorials, one depicting embryonic folding and the other showing development of the nervous system after neural tube formation. The goal was to enhance the traditional teaching format-lecture combined with printed diagrams, text, and existing computer animations-with customized, guided, Web-based learning modules that surpassed existing resources. To assess module effectiveness, we compared quiz performance of control groups who attended lecture and did not use a supporting module, with study groups who used a module in addition to attending lecture. We also assessed our students' long-term retention of the material, comparing classes who had used the module with students from a previous year that had not seen the module. Our data analysis suggests that students who used a module performed better than those given only traditional resources if they used the module after they were already somewhat familiar with the material. The findings suggest that our modules-and possibly computer-assisted-instruction modules in general-are more useful if used toward the later stages of learning, rather than as an initial resource. Furthermore, our data suggest that the animation aids in long-term retention. Both medical students at the University of Cincinnati and medical faculty from across the country commented favorably on their experiences with the embryonic development modules. Copyright 2008 American Association of Anatomists

Impaired embryonic development in mice overexpressing the RNA-binding protein TIAR.

Directory of Open Access Journals (Sweden)

Yacine Kharraz

Full Text Available BACKGROUND: TIA-1-related (TIAR protein is a shuttling RNA-binding protein involved in several steps of RNA metabolism. While in the nucleus TIAR participates to alternative splicing events, in the cytoplasm TIAR acts as a translational repressor on specific transcripts such as those containing AU-Rich Elements (AREs. Due to its ability to assemble abortive pre-initiation complexes coalescing into cytoplasmic granules called stress granules, TIAR is also involved in the general translational arrest observed in cells exposed to environmental stress. However, the in vivo role of this protein has not been studied so far mainly due to severe embryonic lethality upon tiar invalidation. METHODOLOGY/PRINCIPAL FINDINGS: To examine potential TIAR tissue-specificity in various cellular contexts, either embryonic or adult, we constructed a TIAR transgenic allele (loxPGFPloxPTIAR allowing the conditional expression of TIAR protein upon Cre recombinase activity. Here, we report the role of TIAR during mouse embryogenesis. We observed that early TIAR overexpression led to low transgene transmission associated with embryonic lethality starting at early post-implantation stages. Interestingly, while pre-implantation steps evolved correctly in utero, in vitro cultured embryos were very sensitive to culture medium. Control and transgenic embryos developed equally well in the G2 medium, whereas culture in M16 medium led to the phosphorylation of eIF2alpha that accumulated in cytoplasmic granules precluding transgenic blastocyst hatching. Our results thus reveal a differential TIAR-mediated embryonic response following artificial or natural growth environment. CONCLUSIONS/SIGNIFICANCE: This study reports the importance of the tightly balanced expression of the RNA-binding protein TIAR for normal embryonic development, thereby emphasizing the role of post-transcriptional regulations in early embryonic programming.

Imaging Findings of Embryonal Cell Carcinoma in Ovary:A Case Report

International Nuclear Information System (INIS)

Kim, Hee Kyung; Park, Cheol Min; Choi, Jae Woong; Seol, Hae Young; Kim, Kyeong Ah

2004-01-01

Embryonal cell carcinoma is one of the malignant germ cell tumors. This tumor is commonly encountered in the testis, however, it rarely occurs in the ovary. To the best of our knowledge, no imaging findings of ovarian embryonal cell carcinoma have previously been reported. We describe the US and MRI findings of such a case

ALTERATIONS IN THE DEVELOPING TESTIS TRANSCRIPTOME FOLLOWING EMBRYONIC VINCLOZOLIN EXPOSURE

OpenAIRE

Clement, Tracy M.; Savenkova, Marina I.; Settles, Matthew; Anway, Matthew D.; Skinner, Michael K.

2010-01-01

The current study investigates the direct effects of in utero vinclozolin exposure on the developing F1 generation rat testis transcriptome. Previous studies have demonstrated that exposure to vinclozolin during embryonic gonadal sex determination induces epigenetic modifications of the germ line and transgenerational adult onset disease states. Microarray analyses were performed to compare control and vinclozolin treated testis transcriptomes at embryonic day 13, 14 and 16. A total of 576 di...

Characterization of glycolipid galactosyltransferases from embryonic chicken brain

International Nuclear Information System (INIS)

Kyle, J.W.

1985-01-01

Glycolipid galactosyltransferases (GalT-3 and GalT-4) were solubilized from a membrane fraction isolated from embryonic chicken brain. The profiles of specific activity and total units per brain of GalT-3 and GalT-4 varied with embryonic age. GalT-4 had the highest specific activity at 9 days of embryonic development and showed a steady decrease until hatching. GalT-3 showed a gradual increase in specific activity. Both GalT3 and GalT-4 showed a steady increase in total units per brain throughout embryonic development. The solubilized enzymes could be separated using gel filtration, ion exchange chromatography or affinity chromatography on α-lactalbumin-agarose. Data obtained in the study imply that GalT-4 is involved in both glycoprotein and glycolipid biosynthesis. Glycosphingolipid products from GalT-3 and GalT-4 catalyzed reactions labeled with [ 14 C]galactose comigrated with authentic GMI and nLcOse 4 Cer, when examined by thin layer chromatography and autoradiography. Studies with galactosidases revealed that all of the enzyme products formed by GalT-3 and GalT-4 contained a [ 14 C]-galactose in a β anomeric linkage. Periodate oxidation studies of Gal-[ 14 C]GlcNAc, formed by purified GalT-4 using [ 14 C]GlcNAc as the acceptor, demonstrated that approximately 70% of the linkage formed was Galβ1-4GlcNAc and 30% was Galβ1-3GlcNAc. Studies on the susceptibility of [ 14 C]Gal-GlcNAc to base catalyzed β-elimination also suggested the presence of approximately 30% Galβ1-3GlcNAc

Cosmic strings in an open universe: Quantitative evolution and observational consequences

International Nuclear Information System (INIS)

Avelino, P.P.; Caldwell, R.R.; Martins, C.J.

1997-01-01

The cosmic string scenario in an open universe is developed - including the equations of motion, a model of network evolution, the large angular scale cosmic microwave background (CMB) anisotropy, and the power spectrum of density fluctuations produced by cosmic strings with dark matter. We first derive the equations of motion for a cosmic string in an open Friedmann-Robertson-Walker (FRW) space-time. With these equations and the cosmic string stress-energy conservation law, we construct a quantitative model of the evolution of the gross features of a cosmic string network in a dust-dominated, Ω 2 /Mpc. In a low density universe the string+CDM scenario is a better model for structure formation. We find that for cosmological parameters Γ=Ωh∼0.1 - 0.2 in an open universe the string+CDM power spectrum fits the shape of the linear power spectrum inferred from various galaxy surveys. For Ω∼0.2 - 0.4, the model requires a bias b approx-gt 2 in the variance of the mass fluctuation on scales 8h -1 Mpc. In the presence of a cosmological constant, the spatially flat string+CDM power spectrum requires a slightly lower bias than for an open universe of the same matter density. copyright 1997 The American Physical Society

Gravity with free initial conditions: A solution to the cosmological constant problem testable by CMB B -mode polarization

Science.gov (United States)

Totani, Tomonori

2017-10-01

In standard general relativity the universe cannot be started with arbitrary initial conditions, because four of the ten components of the Einstein's field equations (EFE) are constraints on initial conditions. In the previous work it was proposed to extend the gravity theory to allow free initial conditions, with a motivation to solve the cosmological constant problem. This was done by setting four constraints on metric variations in the action principle, which is reasonable because the gravity's physical degrees of freedom are at most six. However, there are two problems about this theory; the three constraints in addition to the unimodular condition were introduced without clear physical meanings, and the flat Minkowski spacetime is unstable against perturbations. Here a new set of gravitational field equations is derived by replacing the three constraints with new ones requiring that geodesic paths remain geodesic against metric variations. The instability problem is then naturally solved. Implications for the cosmological constant Λ are unchanged; the theory converges into EFE with nonzero Λ by inflation, but Λ varies on scales much larger than the present Hubble horizon. Then galaxies are formed only in small Λ regions, and the cosmological constant problem is solved by the anthropic argument. Because of the increased degrees of freedom in metric dynamics, the theory predicts new non-oscillatory modes of metric anisotropy generated by quantum fluctuation during inflation, and CMB B -mode polarization would be observed differently from the standard predictions by general relativity.

Transcriptome Landscapes of Mammalian Embryonic Cells

NARCIS (Netherlands)

Brinkhof, B.

2015-01-01

This thesis describes research on gene expression profiles from different embryonic stages and cell types to identify genes involved in pluripotency or differentiation in bovine and porcine cells. The results are compared with data from other mammals. RNA expression profiles of morula and blastocyst

Optical modeling and polarization calibration for CMB measurements with ACTPol and Advanced ACTPol

Science.gov (United States)

Koopman, Brian; Austermann, Jason; Cho, Hsiao-Mei; Coughlin, Kevin P.; Duff, Shannon M.; Gallardo, Patricio A.; Hasselfield, Matthew; Henderson, Shawn W.; Ho, Shuay-Pwu Patty; Hubmayr, Johannes; Irwin, Kent D.; Li, Dale; McMahon, Jeff; Nati, Federico; Niemack, Michael D.; Newburgh, Laura; Page, Lyman A.; Salatino, Maria; Schillaci, Alessandro; Schmitt, Benjamin L.; Simon, Sara M.; Vavagiakis, Eve M.; Ward, Jonathan T.; Wollack, Edward J.

2016-07-01

The Atacama Cosmology Telescope Polarimeter (ACTPol) is a polarization sensitive upgrade to the Atacama Cosmology Telescope, located at an elevation of 5190 m on Cerro Toco in Chile. ACTPol uses transition edge sensor bolometers coupled to orthomode transducers to measure both the temperature and polarization of the Cosmic Microwave Background (CMB). Calibration of the detector angles is a critical step in producing polarization maps of the CMB. Polarization angle offsets in the detector calibration can cause leakage in polarization from E to B modes and induce a spurious signal in the EB and TB cross correlations, which eliminates our ability to measure potential cosmological sources of EB and TB signals, such as cosmic birefringence. We calibrate the ACTPol detector angles by ray tracing the designed detector angle through the entire optical chain to determine the projection of each detector angle on the sky. The distribution of calibrated detector polarization angles are consistent with a global offset angle from zero when compared to the EB-nulling offset angle, the angle required to null the EB cross-correlation power spectrum. We present the optical modeling process. The detector angles can be cross checked through observations of known polarized sources, whether this be a galactic source or a laboratory reference standard. To cross check the ACTPol detector angles, we use a thin film polarization grid placed in front of the receiver of the telescope, between the receiver and the secondary reflector. Making use of a rapidly rotating half-wave plate (HWP) mount we spin the polarizing grid at a constant speed, polarizing and rotating the incoming atmospheric signal. The resulting sinusoidal signal is used to determine the detector angles. The optical modeling calibration was shown to be consistent with a global offset angle of zero when compared to EB nulling in the first ACTPol results and will continue to be a part of our calibration implementation. The first

A Guide to Designing Future Ground-based CMB Experiments

Energy Technology Data Exchange (ETDEWEB)

Wu, W. L.K. [Stanford Univ., CA (United States); Kavli Inst. for Particle Astrophysics and Cosmology, Menlo, Park, CA (United States); Errard, J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Univ. of California, Berkeley, CA (United States); Dvorkin, C. [Inst. for Advanced Study, Princeton, NJ (United States); Kuo, C. L. [Stanford Univ., CA (United States); Kavli Inst. for Particle Astrophysics and Cosmology, Menlo, Park, CA (United States); Lee, A. T. [Univ. of California, Berkeley, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McDonald, P. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Slosar, A. [Brookhaven National Lab. (BNL), Upton, NY (United States); Zahn, O. [Univ. of California, Berkeley and Lawrence Berkeley National Lab. (LBNL), CA (United States)

2014-02-18

In this follow-up work to the High Energy Physics Community Summer Study 2013 (HEP CSS 2013, a.k.a. Snowmass), we explore the scientific capabilities of a future Stage-IV Cosmic Microwave Background polarization experiment (CMB-S4) under various assumptions on detector count, resolution, and sky coverage. We use the Fisher matrix technique to calculate the expected uncertainties in cosmological parameters in vΛCDM that are especially relevant to the physics of fundamental interactions, including neutrino masses, effective number of relativistic species, dark-energy equation of state, dark-matter annihilation, and inflationary parameters. To further chart the landscape of future cosmology probes, we include forecasted results from the Baryon Acoustic Oscillation (BAO) signal as measured by DESI to constrain parameters that would benefit from low redshift information. We find the following best 1-σ constraints: σ(M_v ) = 15 meV, σ(N_eff ) = 0.0156, Dark energy Figure of Merit = 303, σ(p_ann) = 0.00588 x 3 x 10^-26 cm³/s/GeV, σ( Ω_K) = 0.00074, σ(n_s) = 0.00110, σ( α_s) = 0.00145, and σ(r) = 0.00009. We also detail the dependences of the parameter constraints on detector count, resolution, and sky coverage.

The Evolutionary Economics of Embryonic-Sac Fluids in Squamate Reptiles.

Science.gov (United States)

Bonnet, Xavier; Naulleau, Guy; Shine, Richard

2017-03-01

The parchment-shelled eggs of squamate reptiles take up substantial water from the nest environment, enabling the conversion of yolk into neonatal tissue and buffering the embryo against the possibility of subsequent dry weather. During development, increasing amounts of water are stored in the embryonic sacs (i.e., membranes around the embryo: amnion, allantois, and chorion). The evolution of viviparity (prolonged uterine retention of developing embryos) means that embryonic-sac fluid storage now imposes a cost (increased maternal burdening), confers less benefit (because the mother buffers fetal water balance), and introduces a potential conflict among uterine siblings (for access to finite water supplies). Our data on nine species of squamate reptiles and published information on three species show that the embryonic-sac fluids comprise around 33% of neonatal mass in viviparous species versus 94% in full-term eggs of oviparous squamates. Data on parturition in 149 vipers (Vipera aspis, a viviparous species) show that larger offspring store more fluids in their fetal sacs and that an increase in litter size is associated with a decrease in fluid-sac mass per offspring. Overall, the evolutionary transition from oviparity to viviparity may have substantially altered selective forces on offspring packaging and created competition among offspring for access to water reserves during embryonic development.

Meeting embryonic requirements of broilers throughout incubation: a review

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R Molenaar

2010-09-01

Full Text Available During incubation of chicken embryos, environmental conditions, such as temperature, relative humidity, and CO2 concentration, must be controlled to meet embryonic requirements that change during the different phases of embryonic development. In the current review, the effects of embryo temperature, egg weight loss, and CO2 concentration on hatchability, hatchling quality, and subsequent performance are discussed from an embryonic point of view. In addition, new insights related to the incubation process are described. Several studies have shown that a constant eggshell temperature (EST of 37.5 to 38.0°C throughout incubation results in the highest hatchability, hatchling quality, and subsequent performance. Egg weight loss must be between 6.5 and 14.0% of the initial egg weight, to obtain an adequate air cell size before the embryo internally pips. An increased CO2 concentration during the developmental phase of incubation (first 10 days can accelerate embryonic development and hatchability, but the physiological mechanisms of this acceleration are not completely understood. Effects of ar increased CO2 concentration during late incubation also need further investigation. The preincubation warming profile, thermal manipulation, and in ovo feeding are new insights related to the incubation process and show that the optimal situation for the embryo during incubation highly depends on the conditions of the eggs before (storage duration and during incubation (environmental conditions and on the conditions of the chickens after hatching (environmental temperature.