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  1. Psico-Oncologia e manejo de procedimentos invasivos em oncologia pediátrica: uma revisão de literatura

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    Costa Jr.,Áderson L.

    1999-01-01

    Este texto descreve alguns tópicos de pesquisa em Psico-Oncologia Pediátrica, discutindo-se a necessidade da implementação de estudos de intervenção que investiguem, entre outros temas, o manejo de procedimentos médicos invasivos em Oncologia e o(s) efeito(s) das intervenções efetuadas, pelos profissionais de saúde, sobre o repertório de comportamentos da criança. Descreve-se e analisa-se, criticamente, as principais medidas tomadas em estudos que avaliam o comportamento de crianças submetida...

  2. Doença de Coats: perfil de casos encaminhados para serviço referência em oncologia ocular Coats Disease: profile of patients referred to a reference ocular oncology service

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    Eduardo Ferrari Marback

    2007-12-01

    Full Text Available OBJETIVO: Relatar o perfil de pacientes com doença de Coats encaminhados para afastar o diagnóstico de retinoblastoma. MÉTODOS: Realizado estudo retrospectivo, com base na revisão de prontuários e exames de imagem, de dez pacientes consecutivos. Foram avaliados os dados referentes à idade, sexo, queixa principal, estágio da doença à apresentação, tratamento e evolução. RESULTADOS: A média de idade à apresentação foi de 43,9 meses. Oito pacientes eram do sexo masculino. Leucocoria ou estrabismo foram as principais queixas, presentes em nove casos. Oito pacientes tinham doença em estágio 3B, um estágio 3A e um estágio 2B. Dos oito casos com descolamento total de retina (3B em sete foi optado apenas pela observação e um submetido a retinopexia sem sucesso. O caso com descolamento parcial (3A foi tratado por crioterapia e depois feita fotocoagulação por laser diodo, evoluindo com reaplicação da retina e obliteração das teleangiectasias. O caso sem descolamento associado (2B foi tratado por fotocoagulação por laser de argônio, com boa obliteração dos vasos anormais. A acuidade visual final foi de percepção luminosa em 3 e ausência de percepção luminosa em 5 dos 8 casos com doença 3B, os casos com doença 3A e 2B mantiveram visão de movimentos de mão. Nenhum dos casos evoluiu para glaucoma neovascular no segmento médio de 26,7 meses. CONCLUSÃO: A maioria dos pacientes com doença de Coats encaminhados para afastar a suspeita de retinoblastoma apresenta doença avançada ao diagnóstico. Nestes casos, devido ao péssimo prognóstico visual e alta complexidade do tratamento cirúrgico, pode-se optar apenas pela observação.PURPOSE: To report the profile of Coats' disease patients, referred to exclude retinoblastoma. METHODS: Retrospective study of medical charts from ten consecutive patients. Data evaluated include age at diagnosis, gender, chief complain, disease stage, treatment and evolution. RESULTS: Mean

  3. Psico-Oncologia e manejo de procedimentos invasivos em oncologia pediátrica: uma revisão de literatura

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    Costa Jr. Áderson L.

    1999-01-01

    Full Text Available Este texto descreve alguns tópicos de pesquisa em Psico-Oncologia Pediátrica, discutindo-se a necessidade da implementação de estudos de intervenção que investiguem, entre outros temas, o manejo de procedimentos médicos invasivos em Oncologia e o(s efeito(s das intervenções efetuadas, pelos profissionais de saúde, sobre o repertório de comportamentos da criança. Descreve-se e analisa-se, criticamente, as principais medidas tomadas em estudos que avaliam o comportamento de crianças submetidas a procedimentos médicos invasivos, apontando-se a pesquisa comportamental como útil à geração de informações acerca da relação funcional entre o contexto de procedimentos invasivos e os comportamentos da criança.

  4. Cuidado paliativo em oncologia pediátrica na formação do enfermeiro

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    Guimarães, Tuani Magalhães; Silva, Liliane Faria da; Santo, Fátima Helena Espírito; Moraes, Juliana Rezende Montenegro Medeiros de; Pacheco, Sandra Teixeira de Araújo

    2017-01-01

    RESUMO Objetivo Identificar e descrever a visão dos acadêmicos de enfermagem sobre os cuidados paliativos em oncologia pediátrica durante a graduação. Método Pesquisa exploratória, abordagem qualitativa, desenvolvida em uma Escola de Enfermagem no Rio de Janeiro. A coleta de dados ocorreu de setembro a novembro de 2014, através de entrevistas semiestruturadas, com 20 acadêmicos do último período de graduação. A análise temática dos dados foi realizada. Resultados Foram elaboradas duas u...

  5. Resiliência na área da Enfermagem em Oncologia Resiliencia en el área de Enfermería en Oncologia Resilience and oncology nursing

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    Denise de Assis de Corrêa Sória

    2009-10-01

    Full Text Available Este estudo objetivou mapear a produção científica, nacional e internacional, sobre a resiliência na Enfermagem em Oncologia e discutir sua aplicabilidade na assistência. Resiliência origina-se do latim resiliens e significa saltar para trás, voltar, ser impelido, recuar, encolher-se, romper. Trata-se de revisão sistemática sem meta análise nas bases de dados Public Medical (PubMed, Literatura Internacional em Ciências da Saúde (Medline, Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS e Base de Dados de Enfermagem (BDENF e nos sites da Oncology Nursing Society e da International Society of Nurses in Cancer Care. Os descritores foram: resilience e nursing; resilience, cancer e oncology; resilience, nursing, cancer e oncology; resiliência e enfermagem; resiliência, câncer e oncologia; resiliência, enfermagem, câncer e oncologia. Foram encontrados 116 artigos e selecionados cinco artigos que abordam a resiliência vinculada à Enfermagem em Oncologia. Verifica-se uma lacuna na utilização do conceito na Enfermagem em Oncologia na América Latina, e incipiência nas produções internacionais. Há necessidade do incremento da abordagem da resiliência nessa área e ampliação da discussão na temática.En este estudio se tuvo como objetivo listar la producción científica nacional e internacional, sobre la resiliencia en el área de Enfermería en Oncología y discutir su aplicabilidad en la asistencia. La resiliencia se origina del latin resiliens y significa saltar hacia atrás, volver, ser impelido, retroceder, encogerse, romper. Se trata de una revisión sistemática sin meta análisis realizada en las bases de datos Public Medical (PubMed, Literatura Internacional en Ciencias de la Salud (Medline, Literatura Latino-Americana y del Caribe en Ciencias de la Salud (LILACS y Base de Datos de Enfermería (BDENF y en los sites de la Oncology Nursing Society y de la International Society of Nurses in Cancer

  6. A comunicação profissional-paciente em oncologia: uma compreensão psicanalítica

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    Bianchini, Daniela Cristina Silva

    2015-01-01

    Esta dissertação é composta por dois artigos empíricos escritos a partir da pesquisa realizada sobre a comunicação profissional–paciente em oncologia. O primeiro estudo refere-se à percepção da comunicação profissional-paciente sob o enfoque dos pacientes com câncer. Foram entrevistados 14 pacientes adultos que estavam realizando quimioterapia, em diferentes estágios da doença (sete metastáticos). Destes, oito eram homens. O segundo estudo apresenta a percepção dos profissionais que atendem p...

  7. A CONSTRUÇÃO DO CUIDADO EM PSICO-ONCOLOGIA NA EXTENSÃO UNIVERSITÁRIA

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    Cintia Bragheto Ferreira

    2016-05-01

    Full Text Available O câncer é uma doença que acomete de forma crescente a população mundial, o que logicamente aumenta a demanda por serviços de saúde, dentre eles os serviços de apoio psicológico. A partir disso, foi criado o projeto de extensão em Psico-Oncologia, vinculado a um curso de Psicologia de uma universidade pública localizada em Goiás. O projeto, ancorado na perspectiva construcionista social, objetiva a capacitação de discentes para o trabalho na área da Psico-Oncologia visando: uma assistência comprometida com o cuidado integral; o empoderamento dos participantes, assim como a construção de saúde mesmo em meio à enfermidade. A demanda é encaminhada para o serviço escola de Psicologia da universidade pública, por duas organizações municipais, que auxiliam os usuários no deslocamento e estadia nos municípios de realização dos acompanhamentos e tratamentos para o câncer. Parte dos atendimentos é feita na clínica escola, e os doentes mais debilitados são atendidos em suas próprias residências. Os atendimentos psicológicos são realizados nas modalidades individual e grupal. Os registros produzidos a partir de cada atendimento realizado mostram que os participantes têm construído possibilidades mais positivas de vivência da enfermidade, com diminuição do medo do câncer; sentidos de vida; possibilidades de participação no autocuidado; reafirmação da superação e o fortalecimento de laços afetivos. Além desses resultados, o projeto também tem contribuído para a formação de futuros profissionais de saúde comprometidos com a humanização da assistência.

  8. O desenvolvimento da psico-oncologia: implicações para a pesquisa e intervenção profissional em saúde

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    Áderson L. Costa Junior

    Full Text Available Este artigo, de caráter descritivo e crítico, apresenta a área da psico-oncologia como integrante do contexto da psicologia da saúde, incluindo seus objetivos e principais tópicos de interesse científico e profissional. O texto inclui, ainda, uma síntese das principais temáticas estudadas em psico-oncologia e apresentadas em congressos brasileiros da área. Discute-se a necessidade da implementação de pesquisas científicas, com rigor metodológico, úteis à promoção de condições favoráveis ao atendimento especializado de pacientes submetidos a tratamento médico e seus familiares, bem como a implementação de oportunidades de formação teórico-técnica específicas para a área.

  9. Saúde, sujeito e invenção: o trabalho clínico em oncologia pediátrica

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    Nina Gomes Costa

    2016-03-01

    Full Text Available Este artigo, tendo como referência a Psicanálise e a abordagem de Canguilhem quanto à sua concepção de saúde, apresenta um fragmento clínico em oncologia pediátrica, e propõe uma discussão sobre a concepção de saúde no contexto de intervenções técnicas complexas. Este trabalho volta-se para o resgate da dimensão de sujeito revelando que a saúde, nesses pacientes, diz respeito sobretudo à possibilidade presente em cada um de criar formas possíveis de viver.

  10. Enfermeiro Clinico Especialista: um modelo de pratica avancada de enfermagem em oncologia pediatrica no Brasil

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    Carla goncalves Dias

    2013-12-01

    Full Text Available O objetivo deste artigo é relatar a experiência de implantação do modelo de prática avançada de enfermagem por meio da incorporação do enfermeiro clínico especialista na composição do quadro de enfermagem. As autoras apresentam o conceito desse modelo e descrevem seu processo de implantação em uma instituição de referência no cuidado à criança e ao adolescente com câncer da cidade de São Paulo, Brasil. Na avaliação das enfermeiras clínicas especialistas, o principal resultado obtido com a adoção do modelo refere-se ao fortalecimento do papel do enfermeiro como profissional de referência para a articulação das diferentes demandas de cuidado à criança, ao adolescente e ao adulto jovem com câncer e sua família. Também destacam a satisfação dos usuários com o estreitamento da relação paciente, família e enfermeira clínica, em todas as etapas do processo de cuidar.

  11. Performance Status e a assistência odontológica hospitalar em oncologia

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    Costa, José Ricardo Sousa

    2011-01-01

    O objetivo do presente estudo foi verificar a prevalência de alterações bucais em pacientes oncológicos sob internação hospitalar de acordo com a condição clínica geral, mensurada pela escala de Performance Status ECOG, além de subsidiar a criação de condutas odontológicas para a prevenção, suporte e tratamento de tais alterações neste seleto grupo de pacientes. O estudo foi prospectivo e observacional realizado no período de 6 meses, através de avaliação semanal de pacientes portadores de...

  12. Componentes oculares em anisometropia The ocular components in anisometropia

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    David Tayah

    2007-06-01

    Full Text Available OBJETIVO: Comparar as correlações dos componentes oculares (comprimento axial, comprimento do segmento anterior, poder médio da córnea, profundidade da câmara vítrea e poder refrativo equivalente com o erro refrativo total do olho portador da menor e da maior ametropia em anisométropes. MÉTODOS: Foi realizado um "survey" analítico conduzido em população de 68 anisométropes de duas ou mais dioptrias atendida no Ambulatório da Clinica Oftalmológica do Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo Os anisométropes foram submetidos à refração estática objetiva e subjetiva, ceratometria e biometria ultra-sônica. RESULTADOS: Não houve diferença significativa entre os valores dos componentes oculares medidos dos olhos portadores da menor e da maior ametropia. Os olhos portadores da menor ametropia apresentaram as mesmas correlações significantes observadas em olhos emétropes, ou seja, correlação da refração com comprimento do segmento anterior e comprimento axial, e correlação do comprimento axial com poder corneano e profundidade da câmara vítrea. Os olhos portadores da maior ametropia apresentaram correlação significante da refração com o comprimento axial e do comprimento axial com a profundidade da câmara vítrea. Ainda em ambos os olhos observou-se correlação significante do poder do cristalino com a profundidade da câmara anterior. CONCLUSÃO: Os olhos portadores da menor ametropia desenvolveram as correlações mais freqüentemente observadas nos olhos emétropes. Os olhos portadores da maior ametropia não desenvolveram as mesmas correlações dos emétropes.PURPOSE: To asses the correlation between ocular components (axial length, anterior segment length, corneal power, vitreous length and equivalent power of the eye and refractive error in eyes with higher and lower ametropia of subjects with anisometropia. METHODS: An analytical survey was carried out in 68 patients

  13. Microbiota conjuntival em pacientes com alergia ocular

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    Alexandre Mattoso Libório; Maria Cristina Nishiwaki-Dantas; Lycia Mara Jenne Mimica; Paulo Elias Correa Dantas; Ana Luísa Höfling de Lima

    2005-01-01

    OBJETIVO: Avaliar a presença de microbiota aeróbia da conjuntiva de portadores de alergia ocular e comparar a um grupo controle. MÉTODOS: Foram examinados 133 pacientes no período de abril a junho de 2001 divididos em 2 grupos. O grupo A foi composto de 63 portadores de conjuntivite alérgica (sem uso de medicação) e o grupo B de 70 pacientes do ambulatório geral (controle). Foram coletadas amostras do fundo de saco conjuntival do olho direito de todos os pacientes e o material foi semeado em ...

  14. Sob a espada de Dâmocles: a prática de Psicólogas em Oncologia Pediátrica em Recife-Pe

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    Sílvia Raquel Santos de Morais

    Full Text Available A prática de psicólogos em oncologia pediátrica envolve demandas ligadas ao processo de adoecimento e suas implicações psicossociais, e, não raro, iminência de morte e/ou até chances de cura. Assim, tal pesquisa objetivou compreender a prática desses profissionais no Município de Recife- PE. A metodologia foi qualitativa de inspiração fenomenológica, ancorada na ontologia heideggeriana. Os instrumentos utilizados foram: entrevistas, grupo focal e diálogos com nove participantes, além das anotações de campo. As narrativas foram transcritas na íntegra, literalizadas (Schmidt, 1990 e interpretadas mediante a analítica do sentido (Critelli, 2007. A prática caracterizou-se pela coexistência dos seguintes aspectos: longo período de convivência de pacientes e familiares, envolvimento afetivo e proximidade entre profissionais de saúde, familiares e crianças, além da intensidade no que diz respeito aos vínculos estabelecidos. Tais dimensões repercutem nos modos-de-ser e de estar-no-mundo das participantes, fazendo a prática transitar por entre as dimensões ôntica e ontológica do cuidado. Com o tempo, a prática tende a ancorar-se nas experiências de coexistência. Exercício ético de acolhimento à alteridade, impossibilidade de controle dos acontecimentos, além da iminência de morte, perpassam tal prática, levando os profissionais a romper ações isoladas, a redimensionar o saber-fazer e a reinventar modos interventivos por meio da experimentação cotidiana.

  15. Achados oculares em pacientes com mucopolissacaridoses

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    Flávia Silva Villas-Bôas

    2011-12-01

    Full Text Available OBJETIVO: O objetivo deste estudo foi determinar a prevalência e gravidade das complicações oculares em pacientes com mucopolissacaridoses (MPS. MÉTODOS: Vinte e nove pacientes com diagnóstico de mucopolissacaridoses foram estudados. Foram avaliados: idade, sexo, acuidade visual, presença de estrabismo, erros refrativos, exame de fundo de olho, pressão intraocular, espessura corneal central e ultrassonografia ocular. RESULTADOS: Foram avaliados três pacientes com MPS I (12%, 11 pacientes com MPS II (37,9%, um paciente com MPS III (3,4% e 14 pacientes com MPS VI (48,3%. A média de idade foi de 9,5 anos (DP 5,5. Observou-se hipermetropia em 88,5% (23 pacientes e astigmatismo em 51,7% (15 pacientes. A média da acuidade visual corrigida foi de 0,45 logMAR (DP 0,68. A média do equivalente esférico foi +3,57 D (DP 2,46 e da pressão intraocular foi 17 mmHg (DP 3,9. Os achados mais comuns foram: espessamento palpebral 24,1% (7 pacientes; opacidade da córnea, 55,2% dos casos (16 pacientes; atrofia do nervo óptico, 23,1% (6 pacientes; dobras radiais na retina 24% (7 pacientes. O fundo de olho não foi examinado em 3 pacientes devido à opacidade de córnea. A média da espessura do complexo esclera-retina-coroide (ERC medida por ultrassom foi de 1,78 mm (DP 0,51. CONCLUSÃO: Os achados oftalmológicos mais proeminentes foram espessamento palpebral, diminuição da acuidade visual, hipermetropia moderada, opacidade da córnea, dobras radiais na retina perimacular e atrofia do nervo óptico.

  16. Personalidade e câncer de mama: produção científica em Psico-Oncologia

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    Rodrigo Sanches Peres

    Full Text Available O presente estudo se insere no campo da Psico-Oncologia. Objetivou-se empreender uma revisão sistemática da literatura científica dedicada especificamente ao papel da personalidade na evolução da condição clínica e emocional de mulheres acometidas por câncer de mama. Foram consultadas as bases de dados MedLine, PsycINFO, LILACS, SciELO-Brasil e PePSIC. De modo geral, os achados das referências selecionadas apontam que o otimismo enseja uma evolução mais favorável da condição emocional. Além disso, sustentam que pacientes com espírito de luta e manejo apropriado da ansiedade desencadeada por estímulos agressivos tendem a uma melhor condição clínica. Todavia, sugere-se a utilização, em futuras investigações, de escolhas teórico-metodológicas inovadoras para o avanço do conhecimento que atualmente se tem a respeito do assunto em pauta.

  17. Sofrimento psíquico em trabalhadores de enfermagem de uma unidade de oncologia El sufrimiento psiquico de los trabajadores de enfermería de una unidad de oncologia Psychological suffering of nursing professionals at an oncology unit

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    Luziane Zacché Avellar

    2007-12-01

    Full Text Available Esta pesquisa focalizou a realidade de trabalho de técnicos de enfermagem do setor de oncologia de um hospital de Vitória - ES. A nossa hipótese foi que o cenário de múltiplas demandas - com profissionais que vivenciam uma expectativa constante de situações de emergência e de concentração de pacientes graves, sujeitos a internações prolongadas, isolamento e mudanças súbitas no estado geral - contribui para a criação de um ambiente de trabalho que gera sofrimento psíquico no trabalhador. Para a coleta dos dados utilizamos a técnica de observação participante e entrevista semi-estruturada. Os dados foram analisados segundo metodologia qualitativa. Os resultados encontrados indicam que estes fatores combinados contribuem para a criação de um ambiente de trabalho que se caracteriza como estressante e gerador de uma atmosfera emocional comprometida, evidenciando a necessidade de se criarem espaços onde se possa falar dos mais variados sentimentos que decorrem da rotina de trabalho e causam sofrimento psíquico.Esta investigación enfocó la realidad del trabajo de los técnicos de enfermería de una unidad de oncologia de un hospital de la ciudad de Vitória, ES - Brasil. Nuestra hipótesis está basada en la situación que enfrentan los trabajadores que conviven constantemente cuadros de emergencias, aislamientos , cambios súbitos del estado general de los pacientes con posibilidades de internaciones prolongadas y concentración de pacientes graves, contribuyendo todo esto a un ambiente de trabajo que provoca sufrimiento psíquico en los técnicos de enfermería. La técnica utilizada para recopilar los datos que presentamos fue, la de observación- participante y entrevistas semi-estructuradas, analizadas según la metodología cualitativa. Los resultados indican que la combinación de estos factores produce un ambiente de trabajo estresante y generador de una atmosfera emocional comprometida y, que por tanto, precisa de

  18. Modelos experimentais em oncologia: O contributo da cultura de células para o conhecimento da biologia do cancro

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    Mariana Cruz

    2009-07-01

    Full Text Available Resumo: A cultura de tecidos surgiu no século xx (Harrison, 1907 para estudar o comportamento das células animais em ambiente homeostático e em situações de stress.A capacidade de estudar as células a nível molecular relaciona-se com a forma como as células podem crescer e ser manipuladas em laboratório. A cultura de células in vitro permitiu estudar crescimento, diferenciação e morte celular e efectuar manipulações genéticas necessárias ao perfeito conhecimento da estrutura e funções dos genes.A cultura de células estaminais humanas veio colmatar algumas limitações inerentes aos restantes modelos de cultura. Ao que parece, as células estaminais cancerígenas mantêm-se quiescentes nos locais me tastáticos até serem activadas por sinais apropriados do microambiente.Vários estudos revelaram que diferentes tipos de cancros podem surgir da transformação maligna de células estaminais. A eliminação destas células progenitoras tumorais é essencial para o desenvolvimento de novas abordagens terapêuticas mais eficazes em cancros agressivos. Por outro lado, a utilização de células dendríticas modificadas em cultura poderá contribuir para a produção de uma potencial vacina terapêutica eficaz para obter a regressão tumoral. Abstract: In the beginning of the 20th century, tissue culture was started with the aim of studying the behaviour of animal cells in normal and stress conditions.The cell study at molecular level depends on their capacity of growing and how they can be manipulated in laboratory. In vitro cell culture allows us the possibility of studying biological key processes, such as growth, differentiation and cell death, and also to do genetic manipulations essential to the knowledge of structure and genes function.Human stem cells culture provides strategies to circumvent other models’ deficiencies.It seems that

  19. Achados oculares em pacientes com mielomeningocele: 72 casos Ocular findings in 72 patients with meningomyelocele

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    Mônica Fialho Cronemberger

    2000-10-01

    Full Text Available Objetivo: Estudar as alterações oculares em pacientes com mielomeningocele. Material e Método: Realizado estudo retrospectivo em 72 pacientes com mielomeningocele, descrevendo as alterações oculares presentes nessa população, além de correlacionar com a presença ou não de hidrocefalia. Resultados: Dos 72 pacientes com mielomeningocele, com idade variando de 5 meses a 18 anos, 64 (88,9% pacientes tinham hidrocefalia. Destes 64 pacientes, 36 (56,3% tinham estrabismo, sendo que 21 (58,3% eram endotrópicos, 13 (36,1% exotrópicos, 1 (2,8% exofórico e 1 (2,8% com estrabismo discinético. Do total dos 72 pacientes estudados 38 (52,8% eram estrábicos. A anisotropia foi encontrada em 16 (22,2% pacientes, sendo que em 14 (87,5% em A e em 2 (12,5% em V. Todos os 16 pacientes com anisotropia apresentavam hidrocefalia. O erro refrativo mais freqüente foi a hipermetropia encontrada em 64 (44,4% olhos. Atrofia óptica foi encontrada em 9 (12,5% pacientes. Conclusão: A mielomeningocele, associada a hidrocefalia, apresenta uma porcentagem de estrabismo maior do que o encontrado na população normal.Purpose: To study ocular findings in patients with meningomyelocele. Methods: A retrospective study of 72 patients with myelomeningocele was performed to evaluate ocular motility disorders, refractive errors and indirect ophthalmoscopy findings. Results: In a group of 72 patients with myelomeningocele, aged 5 month -- 18 years, 64 (88.9% had hydrocephalus. Of this group of 64 patients, 36 (56.3% had strabismus, 21 (58.3% of whom were esotropic, and 13 (36.1% exotropic, 1 (2.8% exophoric and 1 (2.8% presented sometimes esotropia and sometimes exotropia. Of the total of 72 studied patients, 38 (52.8% had strabismus. Anisotropia was found in 16 (22.2% patients, 14 (87.5% with an A pattern and 2 (12.5% with a V pattern. The most frequent refractive error was hyperopia, found in 64 (44.4% eyes. All the 16 patients with anisotropia had hydrocephalus

  20. Cuidar em oncologia na perspectiva de Alfred Schütz Cuidado en oncología segundo Alfred Schütz Oncological care according Alfred Schütz

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    Regina Célia Popim

    2005-10-01

    Full Text Available O estudo foi realizado com enfermeiros oncológicos em seu cotidiano de trabalho. O objetivo foi compreender a ação subjetiva desses profissionais a partir de sua relação enfermeiro-doente. O referencial fenomenológico, fundamentado nas idéias de Alfred Schütz, possibilitou essa compreensão. Diante de uma questão orientadora: o que significa para você cuidar em oncologia? descreva para mim, foram obtidos depoimentos, os quais, depois de analisados, permitiram chegar ao típico da ação do cuidador enfermeiro neste cotidiano. O estudo revelou que cuidar em oncologia implica em lidar com o humano em situação de fragilidade; requer uma relação de afetividade; é um cuidado que traz consigo a gênese do desgaste profissional. O cuidado em oncologia reveste-se de grande complexidade, requerendo do profissional uma competência que vai para além da esfera técnico-científica. Nesse sentido, o enfermeiro necessita buscar por estratégias que lhe possibilitem o enfrentamento do desgaste a que é submetido em seu trabalho.El estudio fue realizado con enfermeros oncológicos en su cotidiano de trabajo. El objetivo fue comprender la acción subjetiva de esos profesionales desde la relación enfermero-enfermo. El referencial fenomenológico, fundamentado en las ideas de Alfred Schütz, posibilitó esa comprensión. Delante de una cuestión orientadora: ¿qué significa para usted el cuidado en oncología? Descríbame, se obtuvo declaraciones que, tras análisis, permitieron llegar a lo que es típico en la acción cotidiana del cuidador enfermero. El estudio reveló que cuidar en oncología implica tratar con el ser humano en situación de fragilidad; requiere una relación de afectividad; es un cuidado que trae consigo la génesis del desgaste profesional. El cuidado en oncología se reviste de gran complejidad y requiere del profesional una competencia que va más allá de la esfera técnico-científica. En ese sentido, el enfermero

  1. Epidemiologia da alergia ocular e comorbidades em adolescentes

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    Marcos Geraldini

    2013-08-01

    Full Text Available OBJETIVO: A prevalência de conjuntivite alérgica (CA não foi estabelecida. Estimativas sugerem que alergias oculares afetam de 15 a 20% da população mundial, ainda que a maioria dos estudos epidemiológicos abranjam sintomas de alergia nasal e ocular e não sejam específicos a respeito da CA. O objetivo deste estudo foi verificar a prevalência de sintomas, comorbidades e o impacto da alergia ocular em adolescentes. MÉTODOS: Os adolescentes foram selecionados de uma amostra de escolas e preencheram, em sala de aula, um questionário previamente validado sobre os sintomas da CA. O seu diagnóstico foi considerado quando mais de três episódios de prurido ocular foram relatados nos últimos 12 meses. Sintomas relacionados, como lacrimejamento, fotofobia, sensação de corpo estranho, impacto sobre as atividades diárias e diagnóstico de conjuntivite alérgica, foram analisados. RESULTADOS: Foram obtidos questionários de 3.120 adolescentes (média de 13,3±1,1 ano. Nos últimos 12 meses, 1.592 (51% adolescentes tiveram prurido ocular. O sintoma relacionado mais frequente foi lacrimejamento (74%, seguido de fotofobia (50,1% e sensação de corpo estranho (37,1%. A prevalência de conjuntivite alérgica foi de 20,7%, afetando mais pessoas do sexo feminino do que do masculino (56,1% em comparação a 45,9%; p = 0,01. O risco de um adolescente com alergia ocular apresentar asma, rinite e eczema atópico foi (RC = 5,7; IC de 95%: 4,5 a 7,1; (RC = 3,6; IC de 95%: 3,0 a 4,3 e (RC = 2,6; IC de 95%: 2,0 a 3,5, respectivamente. Uma interferência grave nas atividades diárias foi relatada por 30,5%. CONCLUSÕES: Sintomas de alergia ocular são comuns, frequentemente relacionados a outras doenças alérgicas, e causam impacto sobre as atividades diárias de adolescentes.

  2. Fisioterapia no tratamento das mulheres Angolanas com cancro da mama no Centro Nacional de Oncologia

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    Carlos, Joice Vânia da Silva

    2014-01-01

    Mestrado em Fisioterapia O cancro da mama é uma das doenças com maior impacto na sociedade angolana, não só por ser muito frequente e associado a uma imagem de grande gravidade, mas também porque se desenvolve em um órgão cheio de simbolismo na maternidade e na feminilidade. O Centro Nacional de Oncologia (CNO) reúne as principais opções terapêuticas do campo da oncologia: quimioterapia, radioterapia, cirurgia, hormonoterapia e imunoterapia, não sendo, os serviços de fisioterapia parte do ...

  3. Microbiota conjuntival em pacientes com alergia ocular Conjunctival microbiota in patients with ocular allergy

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    Alexandre Mattoso Libório

    2005-12-01

    Full Text Available OBJETIVO: Avaliar a presença de microbiota aeróbia da conjuntiva de portadores de alergia ocular e comparar a um grupo controle. MÉTODOS: Foram examinados 133 pacientes no período de abril a junho de 2001 divididos em 2 grupos. O grupo A foi composto de 63 portadores de conjuntivite alérgica (sem uso de medicação e o grupo B de 70 pacientes do ambulatório geral (controle. Foram coletadas amostras do fundo de saco conjuntival do olho direito de todos os pacientes e o material foi semeado em meios sólidos de cultura (ágar sangue, chocolate e Sabouraud. RESULTADOS: No grupo A, 30 culturas (47,7% foram positivas e no grupo B, 6 (8,6%. Sete bactérias foram isoladas no grupo A e 4 no B. A análise estatística revelou associação significante entre a positividade dos cultivos e conjuntivite alérgica. CONCLUSÃO: Microbiota bacteriana foi mais freqüentemente encontrada nos pacientes com alergia ocular.PURPOSE: To evaluate de presence of conjunctival aerobic microbiota in patients with ocular allergy as compared to a control group. METHODS: One hundred and thirty-three patients were evaluated from April to June 2001 and divided into 2 groups. Sixty-three patients with allergic conjunctivitis (without medication were in group A and 70 patients from the general outpatient clinic were in group B (control group. Samples from the conjunctival sac of the right eye were collected and cultured in solid media (blood, chocolate and Sabouraud agar. RESULTS: In group A, 30 cultures (47.7% were positive and 6 (8.6% in group B. Seven bacteria were isolated from group A and 4 from group B. Statistical analysis revealed significant association between positive cultures and allergic conjunctivitis. CONCLUSION: Bacterial microbiota was more frequently found in patients with ocular allergy.

  4. Retrospective study of ocular disorders in Amazon parrots Estudo retrospectivo das alterações oculares observadas em papagaios

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    Ana Paula Hvenegaard

    2009-12-01

    Full Text Available A retrospective study was conducted to identify the occurrence and types of ocular disorders in 57 Amazon parrots admitted to the Ophthalmology Service, Veterinary Teaching Hospital, School of Veterinary Medicine, University of São Paulo, Brazil from 1997 to 2006. The most frequent observed disorder was cataracts, present in 24 of the 114 examined eyes (57 parrots. Uveitis, ulcerative keratitis and keratoconjunctivitis were frequently diagnosed as well. The cornea was the most affected ocular structure, with 28 reported disorders. Uveal disorders also were commonly observed. Conjunctiva and eyelid disorders were diagnosed in lower frequency. Results suggest that cataracts are common and that cornea, lens and uvea are the most affected ocular structures in Amazon parrots.Realizou-se estudo retrospectivo para identificar a ocorrência e os tipos de alterações oculares observadas em 57 papagaios atendidos no Serviço de Oftalmologia do Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo (USP, de 1997-2006. Catarata em diferentes estágios de evolução foi a alteração ocular mais frequentemente diagnosticada, sendo observada em 24 dos 114 olhos examinados. Uveíte, ceratite ulcerativa e ceratoconjuntivite foram também diagnosticadas. A córnea foi a estrutura ocular mais acometida (28 registros. Alterações uveais foram frequentemente observadas. Alterações das pálpebras e conjuntiva foram observadas em menor freqüência. Concluí-se que catarata foi a alteração mais frequentemente observada e que a córnea, lente e úvea são as estruturas oculares mais susceptíveis a alterações em papagaios.

  5. Prevalência de metástases oculares em pacientes com doença metastática reconhecida: resultados preliminares Prevalence of ocular metastasis in patients with known metastatic disease: preliminary results

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    Zélia Maria da Silva Corrêa

    2005-04-01

    Full Text Available OBJETIVO: Avaliar de forma prospectiva a prevalência de metástases oculares, tumor primário mais freqüente e tecido ocular comprometido com mais freqüência pela metástase. MÉTODOS: Foram avaliados consecutivamente pacientes internados em Hospital de referência em Oncologia (HSR durante o período de janeiro 2001 a julho de 2002, portadores de neoplasia maligna e metástases sistêmicas. Todos os pacientes foram submetidos a exame oftalmológico completo incluindo oftalmoscopia binocular indireta sob midríase farmacológica usando lente de 28 dioptrias e, em casos suspeitos de neoplasia, realizados ultra-som e angiografia fluorescente. Nos casos de dúvida diagnóstica, os pacientes foram submetidos à biópsia aspirativa com agulha fina. O diagnóstico de tumor ocular metastático foi estabelecido com base nas características clínicas e no resultado dos exames complementares citados. RESULTADOS: Os 100 pacientes estudados apresentaram idades entre 17 a 87 anos, sendo 71 do sexo feminino e 29 do masculino. Houve predomínio de indivíduos brancos (n=88 nesse grupo. Vinte e um pacientes apresentaram lesões oculares sugestivas de metástase. O tumor primário que originou metástase ocular mais freqüentemente foi o câncer de mama (28,6%. Avaliando o tipo tumoral separadamente, o carcinoma de pulmão apresentou maior prevalência de metástase para o olho nesta amostra (71,5%. A coróide foi comprometida em 57% dos casos e a queixa ocular principal desses pacientes foi embaçamento ou diminuição da visão. Não houve diferença na freqüência de acometimento entre olho direito e esquerdo. CONCLUSÃO: A prevalência de metástases oculares em pacientes com neoplasia maligna e doença metastática na amostra estudada pareceu significativa. As neoplasias que provocaram metástase ocular com maior freqüência foram: carcinoma de mama e pulmão, sendo que a coróide foi comprometida com maior freqüência.PURPOSE: To evaluate, in a

  6. Estudo do estresse do enfermeiro com dupla jornada de trabalho em um hospital de oncologia pediátrica de Campinas Estudio del estrés del enfermero con doble jornada de trabajo en un hospital de oncologia pediátrica de Campinas Study on the stress over the nurse who works in two shifts at a pediatric oncology hospital in Campinas

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    Roberta Cova Pafaro

    2004-06-01

    Full Text Available Trata-se de um estudo que teve como objetivo investigar a presença e o nível de estresse emocional, os sintomas físicos e psicológicos, a intensidade do estresse e enfermeiros que fazem dupla jornada de trabalho comparados aos que não fazem, num hospital de oncologia pediátrica de Campinas. A população foi composta por 33 enfermeiros, sendo 24 em regime de dupla jornada e 9 em jornada única. Na metodologia foi utilizado o Inventario de Sintoma de Stress LIPP e a Escala Analógica Visual. Os resultados permitiram constatar que os enfermeiros classificados quanto as fases de estresse encontravam-se na fase de resistência, com referencia aos níveis de estresse os mesmos encontravam-se no nível médio de estresse, houve predominância dos sintomas psicológicos e os enfermeiros com dupla jornada estavam mais estressados em relação aos com jornada única.Se trata de un estudio que tuvo como objetivo investigar presencia y nivel de estrés emocional, síntomas físicos y psicológicos, intensidad del estrés y enfermeros que realizan doble jornada de trabajo comparados a los que no lo hacen, en un hospital de oncología pediátrica de Campinas. La población estuvo compuesta por 33 enfermeros, de los cuales 24 en régimen de doble jornada y 9 en jornada única. En la metodología fue utilizado el Inventario de Síntoma de Stress LIPP y la Escala Analógica Visual. Los resultados permitieron constatar que los enfermeros clasificados, en relación a las fases de estrés, se encontraban en la fase de resistencia; con referencia a los niveles de estrés los mismos se encontraban en el nivel medio de estrés; hubo predominio de los síntomas psicológicos y los enfermeros con doble jornada estaban más estresados que los de jornada única.This is a study that aimed investigating the presence and level of emotional stress, the physical and psychological symptoms, the intensity of stress and nurses who have two work shifts compared to the ones

  7. Anomalias oculares em pacientes portadores de deficiência auditiva genética Ocular abnormalities in genetically deaf people

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    Jane Chen

    2000-12-01

    Full Text Available Introdução: Para se verificar a prevalência de anomalias oculares em indivíduos portadores de deficiência auditiva de causa genética definitiva ou suspeita, este trabalho apresenta a avaliação oftalmológica de 97 indivíduos portadores de deficiência auditiva. Pacientes e Métodos: 97 indivíduos com diagnóstico definitivo ou suspeito de causa genética para disacusia foram submetidos a exame clínico oftalmológico completo; destes, 10 foram excluídos. Resultados: 42 (48,28% dos pacientes apresentaram uma ou mais anomalias oculares, 22 (25,29% pacientes apresentaram várias anormalidades oculares e quadro clínico compatíveis com síndromes genéticas estabelecidas. Conclusões: O exame oftalmológico é importante no diagnóstico sindrômico e etiológico de alguns quadros de disacusia, pois as alterações oculares podem ser a única anomalia associada à mesma.Purpose: In order to verify the prevalence of ocular abnormalities in patients who are deaf due to genetic causes, this paper presents the visual assessment of 97 deaf patients. Methods: 97 patients with definite or suspected diagno- sis of congenital and genetic deafness underwent a complete ophthalmologic evaluation; 10 patients were excluded. Results: 42 (48.28% patients presented one or more ocular abnormalities, 22 (25.29% patients presented several abnormalities and clinical manifestations of established genetic diseases. Conclusions: The ocular abnormalities may be the only clinical manifestations associated with deafness. Therefore the ophthalmological examination is a helpful tool for the etiological diagnosis of deafness.

  8. Correlação entre os dados clínicos e histopatológicos dos casos de carcinoma espinocelular oral do Instituto Maranhense de Oncologia Aldenora Bello, em São Luís, MA Correlation between the clinical and histologic data of oral squamous cell carcinoma from Instituto Maranhense de Oncologia Aldenora Bello, in São Luís, MA, Brazil

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    Ana Emília Veloso Coaracy

    2008-02-01

    Full Text Available O objetivo deste estudo foi investigar a existência de correlação entre os dados clínicos e histopatológicos do carcinoma espinocelular oral. Foram avaliados 90 casos de pacientes com diagnóstico de carcinoma espinocelular oral dos arquivos do Instituto Maranhense de Oncologia Aldenora Bello (IMOAB (São Luís, MA. Aplicou-se o teste de correlação de Pearson, em nível de significância de 5%, não tendo sido revelada relação estatisticamente significante (r = 0,095, p = 0,375 entre a classificação clínica TNM (tumor, linfonodo, metástase e a graduação histológica de malignidade (GHM desenvolvida por Wahi (1971 e publicada pela Organização Mundial da Saúde (OMS. Mas houve relação significativa entre a referida graduação histológica de malignidade e o parâmetro clínico tamanho do tumor primário (T (r = 0,229, p = 0,03.The aim of this study was to investigate the existence of correlation between the clinical and histopathological data of oral squamous cell carcinoma. A total of 90 cases of patients diagnosed with oral squamous cell carcinoma were selected from the slide archives of Instituto Maranhense de Oncologia Aldenora Bello (São Luís, MA, Brazil. Pearson’s correlation test was applied and did not reveal a statistically significant correlation (r = 0.095; p = 0.375 between TNM clinical classification and histologic malignancy grading, which was defined by Wahi (1971 and published by the World Health Organization (WHO. There was a significant correlation between the histologic malignancy grading and the size of the primary tumor as a clinical parameter (r = 0.229; p = 0.03.

  9. Alterações oculares em pacientes com tuberculose Ocular manifestation in patients with tuberculosis

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    Simone Ribeiro Araújo de Almeida

    2006-04-01

    Full Text Available OBJETIVO: Analisar os achados clínicos da tuberculose ocular e seus aspectos epidemiológicos. MÉTODOS: Foram revisados prontuários médicos de pacientes que foram atendidos no Departamento de Oftalmologia - setor de Uveíte e AIDS da Unifesp-EPM, São Paulo, Brasil, entre janeiro de 1999 e julho de 2002 e que tiveram diagnóstico de tuberculose ocular. Foram inclusos os pacientes que apresentaram PPD forte reator, epidemiologia positiva para tuberculose e lesão ocular que melhorou com tratamento específico. RESULTADOS: Foram analisados prontuários médicos de 17 pacientes, sendo 12 (70,6% do sexo feminino. A idade média foi de 54 (24-84 anos. O tempo médio entre o início dos sintomas e a primeira consulta foi de 100 dias. Os achados oculares foram inespecíficos nesta ocasião mas prevaleceram as alterações de segmento anterior e 41% dos pacientes apresentavam sinais de tuberculose sistêmica. Alterações como glaucoma, descolamento de retina e hemorragia vítrea foram responsáveis pela redução da acuidade visual. CONCLUSÃO: Embora pouco prevalente, a tuberculose ocular apresenta morbidade elevada. A inespecificidade da apresentação clínica da doença ocular pode atrasar o seu diagnóstico.PURPOSE: To analyze clinical findings of ocular tuberculosis and its epidemiological features. METHODS: Were reviewed clinical files of patients who attended the Ophthalmology - Uveitis and AIDS sector of UNIFESP-EPM, São Paulo, Brazil between January 1999 and July 2002 and had a diagnosis of ocular tuberculosis. Patients who had Mantoux test higher than 10 mm, epidemiological history of tuberculosis and ocular findings that improved after specific treatment were included. RESULTS: Seventeen medical files were analyzed, of those, 12 (70,6% were females. The mean age was 54 (24-84 years. The average time between symptoms and diagnosis was 100 days. Ocular findings at the first interview were multiple but most were at the anterior segment of

  10. Fisioterapia : influência na qualidade de vida da mulher com cancro da mama : contributo para a qualidade do serviço em oncologia

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    Duarte, Nuno Miguel de Faria Bento

    2016-01-01

    RESUMO - O cancro da mama é uma preocupação da saúde pública a nível mundial, pela sua incidência, mortalidade e custos económicos associados. As terapias utilizadas no seu tratamento, embora eficazes, conduzem a alterações de todas as dimensões da Qualidade de Vida (QdV) da mulher com cancro da mama. A garantia de uma qualidade de serviço prestado deve ser uma prioridade das organizações de saúde, sendo a QdV uma medida de resultado. Partindo do pressuposto que em Portugal existe uma diferen...

  11. Cancer, poverty and human development: challenges for nursing care in oncology Cáncer, pobreza y desarrollo humano: desafios para la atención en enfermería oncológica Câncer, pobreza e desenvolvimento humano: desafios para a assistência de enfermagem em oncologia

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    Maria de Fátima Batalha de Menezes

    2007-10-01

    sociales, económicos y culturales.Reflexão sobre a questão da pobreza, o desenvolvimento humano e suas interfaces com a assistência de Enfermagem em Oncologia. Objetivos: identificar os principais tipos de câncer por região; apontar os desafios para a assistência de enfermagem; discutir as possibilidades de atuação da enfermagem em oncologia nesse contexto. Tendo em vista a distribuição demográfica, epidemiológica e sociocultural do câncer no Brasil, articular de forma sistemática o cuidado em oncologia, em situações de pobreza e baixo desenvolvimento humano, constituem um desafio para a Enfermagem, visto que as ações necessárias para prevenção, detecção precoce, tratamento e reabilitação vão da baixa à alta complexidade. Nessa concepção, abre-se a possibilidade de atender às demandas da população, que chega aos serviços especializados em oncologia com uma diversidade de necessidades, que não estão restritas ao acesso ao tratamento antineoplásico, mas acrescidas de carências inerentes a fatores socioeconômicos e culturais.

  12. Metabólitos secundários presentes na Annona muricata L e suas propriedades nutricionais e funcionais em oncologia

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    Erlania Carmo Freitas

    2017-01-01

    Full Text Available A nutrição funcional tem ganhado espaço nos últimos anos por sua ação terapêutica, com destaque para o fruto graviola. Vários estudos bem conduzidos sugerem que o fruto possui quantidades consideráveis de minerais, fibras, compostos antioxidantes e substancias que atuam contra células cancerígenas, com destaque para a ação das acetogeninas. Contudo objetivou-se realizar a quantificação dos compostos fenólicos presentes em polpas da graviola in natura e congelada e realizar uma revisão de trabalhos que justifiquem o uso da graviola na diminuição da proliferação do câncer. Foram identificadas quantidades bastante significativas de compostos fenólicos nas amostras de graviola, porém sem diferenciação do tratamento congelado ou in natura. Logo sugere seu uso na prevenção do câncer e necessitam de mais estudos para a sua utilização no tratamento de pacientes oncológicos. ABSTRACT Secondary Metabolitics Present at Annona Muricata L and Its Nutritional and Functional Properties in Oncology Functional nutrition has gained ground in recent years for its therapeutic action, especially the soursop fruit. Several well-conducted studies suggest that the fruit has considerable amounts of minerals, fiber, antioxidants and substances that act against cancer cells, highlighting the action of acetogenins. However it aimed to perform the quantification of the phenolic compounds present in soursop pulp of fresh and frozen and conduct a review of studies that justify the use of soursop in reducing cancer proliferation. They were identified fairly significant amounts of phenolic compounds in the samples of soursop, however no differentiation of treatment or frozen raw. Logo suggests its use in preventing cancer and need further studies for its use in the treatment of cancer patients.

  13. Sinais e sintomas de doença da superfície ocular em usuários de hipotensores oculares tópicos

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    Beatriz Gomes

    2013-10-01

    Full Text Available OBJETIVO: determinar a prevalência de sinais e sintomas de doença da superfície ocular (OSD em pacientes em uso crônico de hipotensores oculares tópicos. MÉTODOS: Neste estudo transversal, foram recrutados 40 pacientes consecutivos, provenientes do ambulatório de glaucoma de um hospital público localizado no Rio de Janeiro, Brasil. Os mesmos deveriam apresentar: idade maior ou igual a 18 anos, diagnóstico de hipertensão ocular ou glaucoma primário de ângulo aberto e deveriam estar em uso da mesma terapia hipotensora ocular há pelo menos seis meses. Foram considerados: sexo, idade, medicação utilizada e duração do tratamento. Todos os pacientes foram submetidos à avaliação da superfície ocular que incluiu: entrevista por meio do questionário Ocular Surface Disease Index® (OSDI®, tempo de rotura do filme lacrimal, biomicroscopia, avaliação da superfície ocular com fluoresceína e com rosa Bengala. RESULTADOS: A média de pontuação do OSDI® foi 24,6 ± 20,7. A maioria dos pacientes (67,5% apresentou uma pontuação anormal no questionário do OSDI®. Em 25% dos pacientes, a pontuação foi compatível com sintomas leves, em 12,5% com sintomas moderados e em 30% com sintomas graves. Blefarite e ceratite ponteada foram diagnosticadas em 42,5% e 20% dos pacientes respectivamente. Instabilidade do filme lacrimal foi observada em 75% dos pacientes, enquanto que alteração da superfície ocular foi evidenciada pelo teste de rosa bengala em 35% dos pacientes. Foi encontrada correlação positiva (r=0,4 estatisticamente significativa (p=0,01 entre a pontuação do OSDI® e o tempo de duração do tratamento com hipotensores oculares tópicos. CONCLUSÃO: Pacientes em uso crônico de hipotensores oculares tópicos apresentam alta prevalência de sinais e sintomas de OSD. Existe correlação significativa entre a duração do tratamento e a gravidade dos sintomas de OSD.

  14. Entre a teoria parasitária e a oncologia experimental: uma proposta de sistematização da ciência oncológica em Portugal, 1889-1945 Between parasitic theory and experimental oncology: a proposal for systematizing oncological science in Portugal, 1889-1945

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    Rui Manuel Pinto Costa

    2012-06-01

    Full Text Available Focaliza a produção de investigação biomédica sobre o estudo do câncer em Portugal entre 1889 e 1945. Recuperando os principais trabalhos realizados entre finais do século XIX e a primeira metade do XX, foi possível trazer a lume e delimitar um campo de ação científica ainda pouco estudado. Desde a introdução e consolidação dos princípios que definiram a oncologia experimental, detectam-se fases distintas de produção científica, oscilando entre a comprovação de teorias dominantes e a aplicação de métodos de criação artificial da doença. Propõe-se breve sistematização da orientação dos estudos dedicados à oncologia, organizados em patamares de investigação predominantes.This article deals with the bio-medical investigation of cancer studies in Portugal between 1889 and 1945. By examining the main works produced between the end of the nineteenth century and the middle of the twentieth century, it has been possible to illuminate and define a field of scientific endeavour which has been the scope of little study to date. Starting from the introduction and consolidation of the defining principles of experimental oncology, distinct phases can be discerned in the production of scientific material, alternating between support for the dominant theories and the application of methods for artificially creating the disease. In accordance with the principal phases of investigation, a brief systematic overview of the scope of these oncological studies is presented.

  15. Análise clínica e epidemiológica do transplante de medula óssea em um serviço de oncologia pediátrica

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    Castro Jr.,Cláudio Galvão de; Gregianin,Lauro José; Brunetto,Algemir Lunardi

    2003-01-01

    OBJETIVOS: Descrever o perfil e as complicações agudas mais importantes das crianças que receberam transplante de medula óssea no serviço de oncologia pediátrica do Hospital de Clínicas de Porto Alegre. CASUÍSTICA E MÉTODOS: Análise retrospectiva de 41 pacientes, menores de 21 anos, transplantados entre agosto de 1997 até junho de 2002. Deste total, 20 pacientes receberam transplante alogênico, e 21 transplante autogênico. RESULTADOS: No transplante de medula óssea alogênico, a média de idade...

  16. Psico-Oncologia: atuação do psicólogo no Hospital de Câncer de Barretos

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    Camila Saliba Soubhia Scannavino

    2013-04-01

    Full Text Available A Psico-Oncologia surgiu a partir da necessidade do acompanhamento psicológico ao paciente com câncer, a sua família e à equipe que o acompanha. O papel do psicólogo em oncologia propõe o apoio psicossocial e psicoterapêutico diante do impacto do diagnóstico e de suas consequências e mostra a possibilidade de auxílio para melhor enfrentamento e qualidade de vida do doente e de seus familiares. O objetivo deste relato consiste em descrever a atuação desenvolvida por psicólogos do Serviço de Psicologia do Hospital de Câncer de Barretos/Fundação Pio XII - SP, uma instituição médica especializada em oncologia.

  17. Psico-oncologia: história, características e desafios

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    Carvalho Maria Margarida

    2002-01-01

    Full Text Available Este artigo visa oferecer uma visão da Psico-oncologia, através de um resumo da história, do campo de ação e dos problemas específicos da área. Os primeiros estudos da ligação corpo e mente no câncer tiveram início na Grécia, mas esta visão foi abandonada até o século XIX quando Freud voltou a mostrar que o psíquico podia ocasionar processos físicos. A Medicina Psicossomática, a Medicina e a Psicologia Comportamental e a Psicologia da Saúde abriram o caminho para a Psico-Oncologia, hoje muito apoiada pela Psiconeuroimunologia. As características específicas dos psico-oncologistas brasileiros, bem como a sua forma de atuação levaram a uma definição baseada na nossa cultura e realidade. E levaram ao desenvolvimento atual deste campo em nosso meio. Os profissionais da área, entretanto, ainda se vêem frente a uma série de desafios, seja internos, no conteúdo da Psico-Oncologia, seja na afirmação de seu campo de trabalho.

  18. Achados oculares em pacientes com mais de 99 anos Ocular findings in patients older than 99 years

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    Marcela Colussi Cypel

    2006-10-01

    Full Text Available OBJETIVO: Determinar as condições visuais e oculares em indivíduos com mais de 99 anos. MÉTODO: Estudo prospectivo e descritivo de série casos. Trinta idosos com mais de 99 anos se inscreveram no Instituto da Visão da Universidade Federal de São Paulo, de forma voluntária, respondendo à busca ativa. O exame oftalmológico constou de anamnese, ectoscopia, acuidade visual, exame refracional, citologia e cultura de cílios e conjuntiva com antibiograma, teste de Schirmer basal, tempo de ruptura do filme lacrimal, coloração com Rosa Bengala da conjuntiva e córnea, exame de biomicroscopia, tonometria de aplanação e fundoscopia direta e indireta. Foram realizados exames complementares, como retinografia e tomografia de coerência óptica, quando indicados. RESULTADOS: Trinta pacientes acima de 99 anos (média de 101,5±1,8 anos, dos quais, 25 mulheres e 5 homens, foram examinados; destes, 10 não tinham condições de exame completo, em razão de limitações de saúde e mobilidade. A doença sistêmica mais encontrada foi hipertensão arterial (8 pacientes = 40%. Cinco pacientes (25% negaram qualquer doença ou uso de medicação. A melhor acuidade visual corrigida para longe foi de 20/100 ou melhor em 11 pacientes (55% e para perto variou de J4 ou melhor também em 11 pacientes (55%, sendo que sete destes idosos (63% não haviam sido submetidos à cirurgia de catarata. A principal queixa foi dificuldade para leitura em 55% e 40% demonstrou estar satisfeito com a sua visão. A melhora da acuidade com prescrição de óculos novos ocorreu em 4 casos (20%. Catarata foi identificada como comprometendo a visão de forma significativa em 5 casos (25%; porém, apenas 2 concordaram com a cirurgia. A principal causa de baixa visão foi a degeneração macular relacionada à idade, presente em todos os casos; na maioria da vezes (95%, na forma seca. CONCLUSÃO: As necessidades da população nessa faixa etária devem ser entendidas para o

  19. Linfoma de células da zona do manto em anexos oculares: relato de caso

    OpenAIRE

    Anna Paula Lemos de Albuquerque; Jonathan Seiji Aguni; Renato José Bett Correia; Franciele Vegini; André Dalsasso Borges de Souza

    2006-01-01

    Os tumores linfóides dos anexos oculares são neoplasias de crescimento lento que acometem principalmente idosos. O objetivo deste trabalho é relatar um caso de linfoma não-Hodgkin de células da zona do manto, um subtipo raro de linfoma de células B nos anexos oculares. RELATO DO CASO: Paciente masculino de 62 anos com tumoração em pálpebras superiores, região maxilar e cavidade oral, tendo o diagnóstico inicial de doença de Mikulics, evoluiu com acentuado aumento das lesões, apesar da terapêu...

  20. Diagnósticos de enfermagem mais freqüentes em uma unidade de internação de oncologia Diagnósticos de enfermeria mas frecuentes en una unidade de hospitalización de oncología The most frequent nursing diagnoses in an oncology admission unit

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    Rosimeire Aparecida Mendes Lopes

    1997-10-01

    Full Text Available Este trabalho levanta diagnósticos de enfermagem mais freqüentes, a partir do histórico de enfermagem e procedimento médico, com o objetivo de subsidiar a assistência no Serviço de Enfermagem em Oncologia do Centro de Atenção Integral à Saúde da Mulher (CAISM. Os cinco diagnósticos mais freqüentes foram: potencial para infecção, potencial para temperatura corporal alterada, potencial para aspiração e constipação colônica do padrão trocar, e potencial para intolerância à atividade do padrão mover. O histórico estava direcionado para estes padrões, dificultando a interpretação dos dados que envolviam predominantemente aspectos psicossocioculturais e espirituais, que foram registrados de forma pouco clara ou omitidos.El presente trabajo levanta diagnósticos de enfermería más frecuentes, a partir de la historia realizada por enfermería y del procedimiento médico, con el objetivo de ayudar la asistencia en el Servicio de Enfermería en Oncologia del Centro de Atención Integral a la Salud de la Mujer (CAISM. Los cinco diagnósticos más frequentes fueron: potencial para infección, potencial para temperatura corporal alterada, potencial para aspiración y constipación colónica de patrón cambiar y potencial para intolerancia a la actividad del patrón mover. La historia estaba direccionada para estos patrones, dificultando la interpretación de los datos que predominantemente envuelven aspectos psico-socioculturales y espirituales, los que fueron registrados de forma poco clara u omitidos.The aim of this paper was to survey the most frequent nursing diagnoses by means of the nursing history and medical procedure in order to help the care provided at the Oncology Nursing Service of Women Health Whole Care (Centro de Atenção Integral à Saúde da Mulher, CAISM. The five most common diagnoses were: risk for infection, risk for altered body temperature, risk for aspiration and colonic constipation of the exchanging

  1. Stressing factors and coping strategies used by oncology nurses Factores estresantes y estrategias de coping utilizadas por los enfermeros que actúan en oncología Fatores estressantes e estratégias de coping dos enfermeiros atuantes em oncologia

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    Andrea Bezerra Rodrigues

    2008-02-01

    oncologia, são muitos os fatores que podem conduzir o profissional de enfermagem ao stress ocupacional. Para tentar controlar essa situação, o indivíduo pode utilizar estratégias de coping, que é um esforço cognitivo e comportamental utilizado frente a evento estressor. Os objetivos desse estudo foram identificar os fatores estressantes para enfermeiros que atuam em oncologia e verificar as estratégias de coping utilizadas pelos mesmos. Foram utilizados dois questionários: um inventário de dados demográficos, construído pela autora, e o inventário de estratégias de coping de Folkman e Lazarus. Os resultados da pesquisa mostram que os fatores considerados mais estressantes para os enfermeiros de oncologia são: o óbito dos pacientes (28,6%, as situações de emergência (16,9%, os problemas de relacionamento com a equipe de enfermagem (15,5% e as situações relacionadas ao processo de trabalho (15,5%. Na população estudada, a estratégia de coping mais utilizada foi a reavaliação positiva.

  2. Ocular alterations in dogs naturally infected by Leishmania (Leishmania chagasi Alterações oculares em cães infectados naturalmente por Leishmania (Leishmania chagasi

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    F.L.C. Brito

    2006-10-01

    Full Text Available Ocular conditions, anti-Leishmania antibodies and total protein of the aqueous humor were studied in dogs naturally infected by Leishmania (Leishmania chagasi. Fifty dogs were analyzed and assigned into two groups of 25 animals each. All animals were submitted to routine ophthalmic exam. Results showed that 76% of the affected animals presented ocular signs, being uveitis the predominant. The mean of total protein in the aqueous humor of animals with uveitis was higher (PEstudaram-se as condições oculares, os anticorpos anti-Leishmania e os valores de proteína total no humor aquoso de cães infectados naturalmente por Leishmania (Leishmania chagasi. Analisaram-se 50 cães, divididos em dois grupos de 25 animais. Todos os animais foram submetidos a exame oftálmico rotineiro. Os resultados mostraram que 76% dos cães infectados apresentaram sinais oculares, sendo a uveíte a alteração predominante. A média de proteína total no humor aquoso dos animais com uveíte foi maior (P<0,05, que a dos animais com outros sinais oculares ou sem qualquer sinal. Os valores de anticorpos anti-L. chagasi obtidos no plasma foram estatisticamente superiores aos encontrados no humor aquoso (P<0,05.

  3. Comprometimentos oculares em hansenianos: avaliação em consulta de enfermagem

    OpenAIRE

    Brito, Thais Evangelista Fernandes; Caetano, Joselany Afio; Pagliuca, Lorita Marlena Freitag

    2002-01-01

    Estudo exploratório-descritivo e quantitativo. Caracterizou os dados sócio-demográficos, forma clínica e tempo de evolução de hansenianos, identificando alterações oculares correlacionando com forma clínica e tempo de evolução da doença. A coleta de dados incluiu 60 pacientes examinando a força muscular palpebral, estruturas externas, motilidade ocular, sensibilidade corneana, produção lacrimal, campo e acuidade visual. O grupo foi constituído por 39 homens e 21 mulheres; 35 foram pardos, 19 ...

  4. Comprometimentos oculares em hansenianos: avaliação em consulta de enfermagem

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    Thais Evangelista Fernandes Brito

    2002-08-01

    Full Text Available Estudo exploratório-descritivo e quantitativo. Caracterizou os dados sócio-demográficos, forma clínica e tempo de evolução de hansenianos, identificando alterações oculares correlacionando com forma clínica e tempo de evolução da doença. A coleta de dados incluiu 60 pacientes examinando a força muscular palpebral, estruturas externas, motilidade ocular, sensibilidade corneana, produção lacrimal, campo e acuidade visual. O grupo foi constituído por 39 homens e 21 mulheres; 35 foram pardos, 19 brancos e 6 negros. Quanto à forma clinica eram dimorfa (42; virchowiana (13; indeterminada (3e tuberculóide (2. Evolução da doença de 1 a 4 anos para 43 pacientes. Identificadas as alterações oculares: diminuição da produção lacrimal, (32; da força muscular palpebral, (12 e da sensibilidade corneana, (10; hiperemia, (13; lagoftafmo, (8e madarose, (7, predominando nas formas dimorfa, (43 e virchowiana, (15. Os multibacilares apresentam maior comprometimento ocular e não foi possível estabelecer correlação com o tempo de evolução.

  5. Evaluation of the ocular protection for low intensity therapeutic lasers; Avaliacao da protecao ocular para lasers terapeuticos em baixa intensidade

    Energy Technology Data Exchange (ETDEWEB)

    Cordon, Rosely

    2003-07-01

    The low intensity laser therapy (LILT) has been extensively used in medicine and dentistry presenting positive effects. However, the laser radiation can also cause adverse effects. Due to the ocular focalization property, in the wavelength from 400 to 1400 nm, the retina is more susceptible to damage by radiation than any other part of the human body. Then, the ocular protection is frequently emphasized. This protection must attenuate the radiation to a safe level. The International Electrotechnical Commission (IEC) standard IEC 60825-1 suggests safety requirements for medical laser equipment, including the ocular protection, based on maximum permissible exposure levels. The Brazilian legislation adopts a corresponding IEC standard, the NBR IEC 601.2.22, for safety requirements. The aim of this study was to analyze the adequacy of the ocular protectors furnished by four laser equipment manufacturers, commercially available in Brazil, commonly used for LILT. For this purpose, the laser equipment and the respective ocular protectors were characterized. The adequacy was verified according to the IEC standards. It was found, among other results, ocular protectors attenuating to safe levels the radiation emitted by the respective laser equipment, however, presenting inadequate visual transmission. Inefficient protection and protection indicated in cases where they were not necessary were also observed. (author)

  6. Achados oculares em crianças com toxoplasmose congênita

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    Janer Aparecida Silveira Soares

    2011-08-01

    Full Text Available OBJETIVO: Conhecer as lesões oculares mais frequentes encontradas em crianças expostas à toxoplasmose congênita. MÉTODOS: Trata-se de um estudo retrospectivo, a partir de uma coorte histórica, de abordagem quantitativa. Foram avaliadas crianças encaminhadas de um serviço de infectologia pediátrica e inseridas apenas aquelas com diagnóstico confirmado de toxoplasmose congênita. A avaliação oftalmológica incluiu o mapeamento de retina sequencial, sob dilatação pupilar. RESULTADOS: Das 58 crianças presumivelmente expostas ao risco de doença durante a gestação, 20 apresentaram lesões oftalmológicas ao longo do primeiro ano de vida (34 olhos. Destas, 12 estavam assintomáticas ao nascimento. Estrabismo foi registrado em 14 crianças (70%. Em uma criança observou-se ptose palpebral e em outra diminuição da fenda palpebral (microftalmia. Retinocoroidite foi a complicação mais frequente, presente em todas as 20 crianças. Sete crianças apresentaram alterações unilaterais (35% e 13 crianças apresentaram alterações bilaterais (65%, prevalecendo a localização no polo posterior e mácula. CONCLUSÃO: Retinocoroidite e estrabismo destacaram-se como importantes sequelas da toxoplasmose congênita.

  7. Síndrome de Cogan: achados oculares em um caso da forma atípica Cogan's syndrome: ocular findings in an atypical case

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    Ana Karina Santiago de Medeiros Lima

    2006-12-01

    Full Text Available A síndrome de Cogan é entidade multissistêmica rara caracterizada por ceratite intersticial associada à disfunção áudio-vestibular e possível surdez irreversível classificada em duas formas clínicas: típica e atípica. Há discordância na literatura quanto à presença de acometimento corneano na forma atípica. Uma paciente de 32 anos queixando-se de hiperemia e dor ocular, fotofobia e baixa da acuidade visual no olho direito, associada à perda súbita de audição à esquerda, vômitos, diarréia, oligúria, dor na orofaringe e febre. História prévia de semelhante acometimento do olho esquerdo e audição direita. Havia intensa hiperemia conjuntival, esclerite nodular, episclerite e infiltrados circulares no estroma corneano. A paciente recebeu pulsoterapia com metilprednisolona e ciclofosfamida. Evoluiu com grande melhora ocular, porém com resposta auditiva pobre. O caso reportado pode constituir forma típica da síndrome de Cogan (de acordo com autores que defendem o não-acometimento corneano na forma atípica com alguns achados característicos da forma atípica ou um caso da forma atípica da síndrome de Cogan (para aqueles que defendem o acometimento corneano na forma atípica. O diagnóstico diferencial também é discutido.Cogan's syndrome is an unusual multisystemic disease characterized by intersticial keratitis in association with vestibuloauditory dysfunction and possible irreversible deafness, classified into 2 clinical types: typical and atypical. There is disagreement in the literature about corneal disease in the atypical variety. A 32-year-old woman complaining of ocular hyperemia and ocular pain, photophobia and visual acuity loss in the right eye associated with sudden left hearing loss, vomiting, diarrhea, oliguria, oropharynx pain and fever. Previous history of similar disease in left eye and right hearing. There was intense conjunctival hyperemia, nodular scleritis, episcleritis, and circular infiltrates

  8. Modelos experimentais em oncologia: O contributo da cultura de células para o conhecimento da biologia do cancro Experimental models in oncology: Contribution of cell culture on understanding the biology of cancer

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    Mariana Cruz

    2009-08-01

    Full Text Available A cultura de tecidos surgiu no século xx (Harrison, 1907 para estudar o comportamento das células animais em ambiente homeostático e em situações de stress. A capacidade de estudar as células a nível molecular relaciona-se com a forma como as células podem crescer e ser manipuladas em laboratório. A cultura de células in vitro permitiu estudar crescimento, diferenciação e morte celular e efectuar manipulações genéticas necessárias ao perfeito conhecimento da estrutura e funções dos genes. A cultura de células estaminais humanas veio colmatar algumas limitações inerentes aos restantes modelos de cultura. Ao que parece, as células estaminais cancerígenas mantêm-se quiescentes nos locais metastáticos até serem activadas por sinais apropriados do microambiente. Vários estudos revelaram que diferentes tipos de cancros podem surgir da transformação maligna de células estaminais. A eliminação destas células progenitoras tumorais é essencial para o desenvolvimento de novas abordagens terapêuticas mais eficazes em cancros agressivos. Por outro lado, a utilização de células dendríticas modificadas em cultura poderá contribuir para a produção de uma potencial vacina terapêutica eficaz para obter a regressão tumoral.In the beginning of the 20th century, tissue culture was started with the aim of studying the behaviour of animal cells in normal and stress conditions. The cell study at molecular level depends on their capacity of growing and how they can be manipulated in laboratory. In vitro cell culture allows us the possibility of studying biological key processes, such as growth, differentiation and cell death, and also to do genetic manipulations essential to the knowledge of structure and genes function. Human stem cells culture provides strategies to circumvent other models’ deficiencies. It seems that cancer stem cells remain quiescent until activation by appropriated micro-environmental stimulation

  9. Análise clínica e epidemiológica do transplante de medula óssea em um serviço de oncologia pediátrica Clinical and epidemiological analysis of bone marrow transplantation in a pediatric oncology unit

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    Cláudio Galvão de Castro Jr.

    2003-10-01

    Full Text Available OBJETIVOS: Descrever o perfil e as complicações agudas mais importantes das crianças que receberam transplante de medula óssea no serviço de oncologia pediátrica do Hospital de Clínicas de Porto Alegre. CASUÍSTICA E MÉTODOS: Análise retrospectiva de 41 pacientes, menores de 21 anos, transplantados entre agosto de 1997 até junho de 2002. Deste total, 20 pacientes receberam transplante alogênico, e 21 transplante autogênico. RESULTADOS: No transplante de medula óssea alogênico, a média de idade foi de 8,9 + 5,4 anos, sendo 12 pacientes do sexo masculino. As fontes de células foram: medula óssea, 12; sangue periférico, 5; e sangue de cordão umbilical não aparentado, 3. As doenças tratadas foram: leucemia linfóide aguda em 7 pacientes, leucemia mielóide crônica em 2, leucemia mielóide aguda em 4, síndrome mielodisplásica em 2, linfoma de Burkitt em 1, anemia aplástica grave em 1, anemia de Fanconi em 1, síndrome Chediak-Higashi em 1, e imunodeficiência congênita combinada grave em 1. Um paciente desenvolveu doença do enxerto contra hospedeiro aguda grau 2, três pacientes grau 4, e outros três desenvolveram doença do enxerto contra hospedeiro crônica. Todos haviam recebido sangue periférico como fonte de células. A sobrevida global aos 4 anos foi de 70,0 + 10,3%. A principal causa do óbito foi doença do enxerto contra hospedeiro, em três pacientes, e sepse, em outros três. Todos os óbitos ocorreram antes do centésimo dia. Um dos pacientes que recebeu sangue de cordão umbilical não aparentado está vivo, em bom estado e sem uso de medicações 3 anos e 6 meses pós-transplante. No transplante de medula óssea autogênico, a média de idade foi de 8,7 + 4,3 anos, sendo 11 pacientes do sexo masculino. As fontes de células foram: sangue periférico, 16; medula óssea, 3; sangue periférico mais medula óssea, 2. As doenças tratadas foram: tumor de Wilms em 5 pacientes, tumores da família do sarcoma de

  10. Linfoma de células da zona do manto em anexos oculares: relato de caso Mantle-cell lymphoma of the ocular adnexa: a case report

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    Anna Paula Lemos de Albuquerque

    2006-06-01

    Full Text Available Os tumores linfóides dos anexos oculares são neoplasias de crescimento lento que acometem principalmente idosos. O objetivo deste trabalho é relatar um caso de linfoma não-Hodgkin de células da zona do manto, um subtipo raro de linfoma de células B nos anexos oculares. RELATO DO CASO: Paciente masculino de 62 anos com tumoração em pálpebras superiores, região maxilar e cavidade oral, tendo o diagnóstico inicial de doença de Mikulics, evoluiu com acentuado aumento das lesões, apesar da terapêutica imunossupressora. Biopsias da pálpebra superior esquerda e medula óssea revelaram linfoma não-Hodgkin de células B da zona do manto. Apesar da disseminação (estadiamento grau IV, quimioterapia e transplante de medula óssea conduziram à remissão da doença. COMENTÁRIOS CONCLUSIVOS: Apesar da disponibilidade de avançados métodos diagnósticos complementares como a imunofenotipagem e a análise genética molecular, o linfoma representa, para clínicos e patologistas, um desafio quanto ao diagnóstico e ao prognóstico.Ocular adnexal lymphoid tumors are slow-growing neoplasms that affect predominantly the elderly. The purpose of this study is to report a non-Hodgkin lymphoma from mantle zone cells, a rare ocular annexal B-cell lymphoma subtype. CASE REPORT: A 62-year-old male patient with superior eyelid, maxillary and oral tumours, had an initial diagnosis of Mikulics disease, developed lesion enlargement, despite immunosuppressant therapy. Left superior eyelid and bone marrow biopsy revealed non-Hodgkin lymphoma the mantle zone. In spite of dissemination (stage IV, chemotherapy and bone marrow transplant led to disease remission. CONCLUSIVE COMMENTARIES: Despite the availability of advanced complementary diagnostic methods, like immunophenotyping and molecular genetic analysis, lymphoma represents, for physicians and pathologists, a challenge regarding diagnosis and prognosis.

  11. Fisioterapia em oncologia mamária: qualidade de vida e evolução clínico funcional = Physiotherapy for brest cancer: quality of life, clinical and functional evolution

    OpenAIRE

    Leites, Gabriela Tomedi; Knorst, Mara Regina; Lima, Caroline Helena Lazzarotto de; Zerwes, Felipe Pereira; Frison, Verônica Baptista

    2010-01-01

    Objetivo: Avaliar a influência da intervenção fisioterapêutica na qualidade de vida e na evolução clínico funcional de mulheres submetidas ao tratamento do câncer de mama. Materiais e Métodos: Estudo quase-experimental do tipo antes e depois, composto por treinamento de força e flexibilidade, em 10 mulheres submetidas a tratamentos cirúrgico e adjuvante, com duração de oito semanas. Para avaliação da qualidade de vida utilizou-se o questionário WHOQOL-bref. A avaliação clínico funcional foi c...

  12. Fisioterapia em oncologia mamária: qualidade de vida e evolução clínico funcional = Physiotherapy for brest cancer: quality of life, clinical and functional evolution

    Directory of Open Access Journals (Sweden)

    Leites, Gabriela Tomedi

    2010-01-01

    Full Text Available Objetivo: Avaliar a influência da intervenção fisioterapêutica na qualidade de vida e na evolução clínico funcional de mulheres submetidas ao tratamento do câncer de mama. Materiais e Métodos: Estudo quase-experimental do tipo antes e depois, composto por treinamento de força e flexibilidade, em 10 mulheres submetidas a tratamentos cirúrgico e adjuvante, com duração de oito semanas. Para avaliação da qualidade de vida utilizou-se o questionário WHOQOL-bref. A avaliação clínico funcional foi composta por avaliação: da amplitude de movimento (ADM de ombro mensurada por meio de goniometria; da força muscular de flexão, extensão e abdução de ombro avaliada com uma repetição máxima; da dor ao repouso e ao movimento; da sensibilidade; e de edema através da perimetria. Resultados: Não houve variação percentual nas respostas do questionário de qualidade de vida. Na avaliação inicial, as pacientes tinham força muscular e ADM menor no membro superior homolateral à cirurgia e ao final não foi encontrada essa diferença, ocorrendo ganho de força e ADM em ambos os membros. No teste de sensibilidade foi relatado paresia na região cirúrgica e não houve melhora. Após o tratamento houve diminuição de 40% no relato dor forte ao movimentar o braço e na avaliação da dor ao repouso inicialmente 50% referiram dor forte e, após, todas dor fraca. Não houve formação de linfedema. Conclusão: A aplicação do protocolo de exercícios auxiliou na melhora dos parâmetros clínicos funcionais, exceto a paresia, e não ocorreu declínio da qualidade de vida

  13. Aspectos psicológicos em usuários de prótese ocular Psychological aspects in ocular prosthesis users

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    Nara Lúcia Poli Botelho

    2003-10-01

    Full Text Available OBJETIVO: Avaliar os aspectos psicológicos decorrentes da anoftalmia unilateral adquirida, a luta pela recuperação estética com o uso de prótese ocular, assim como os fatores interpessoais envolvidos e a reintegração psicossocial destes pacientes. MÉTODO: Trinta pacientes portadores de anoftalmia unilateral adquirida, sem outras deformidades órbito-palpebrais e usuários de prótese ocular, sendo 16 do sexo masculino e 14 feminino, com idade variando de 12 a 66 anos, idade média 31,6 anos foram submetidos a exame oftalmológico e avaliação psicológica, por meio de questionário padronizado e semidirigido de 66 questões, com duração média de 2 horas no período de janeiro/2000 a março/2001. RESULTADOS: A maior incidência de anoftalmia adquirida (47% está na faixa etária de 0 a 6 anos. Setenta por cento dos pacientes estão em processo de elaboração da perda (n=21 e os mecanismos de defesa mais utilizados em face da situação instalada foram racionalização, repressão, negação e deslocamento. Trinta por cento aceitam a realidade atual. Após o evento desencadeador (ED 37% manifestaram estado depressivo, tendo desaparecido os sintomas em 64% deles. Sessenta por cento adaptaram a prótese ocular (PO logo após o tratamento cirúrgico ao passo que 40% adaptaram-na 2 ou mais anos após o ED. Esteticamente 70% estão satisfeitos ao passo que 30% estão insatisfeitos. Cinqüenta e três por cento revelam auto-estima rebaixada e 37% auto-imagem distorcida. CONCLUSÃO: A integração entre os vários elementos da equipe multidisciplinar constituída por cirurgiões, protéticos, psicólogos e o apoio da família é fundamental durante todo o processo de luto instalado pela perda. Atitude positiva para com a pessoa acometida facilita a vivência da perda em sua totalidade, o que proporcionará a reestruturação dos aspectos interpessoais e reintegração psicossocial da pessoa, pois os recursos de enfrentamento delas estar

  14. Physiotherapy in brest cancer: life quality and function clinical evolution Fisioterapia em oncologia mamária: qualidade de vida e evolução clínico funcional

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    Verônica Baptista Frison

    2010-01-01

    Full Text Available Purpose: to assess physiotherapy intervention impact on quality of life and functional evolution of women who underwent clinical treatment of breast cancer. Methods: almost-experimental study of the type before and after, carried out from March to June of 2009. We have included 10 patients subjected to surgical treatment of breast cancer and who underwent adjuvant treatment. We performed functional evaluation and a quality life questionnaire application, and a intervention protocol proposal with stretching and exercises training since resistance, strength and resistance strength by 8 weeks, supervised by the physiotherapist and home orientation. Results: the proposal with the protocol early implementation with exercises for the comorbidities prevention related to breast câncer treatment helped in clinical and functional parameters improvement. There was no quality of life decline even with the systemic treatment. There was parameters improvement related to satisfaction with health, the ability to daily activities perform, ability to work satisfaction and satisfaction with themselves. Conclusion: the physical therapy must start early and this protocol promoted quality of life maintenance and improved functional capacity of these women.Objetivo: Avaliar a influência da intervenção fisioterapêutica na qualidade de vida e na evolução clínico funcional de mulheres submetidas ao tratamento do câncer de mama. Materiais e Métodos: Estudo quase-experimental do tipo antes e depois, composto por treinamento de força e flexibilidade, em 10 mulheres submetidas a tratamentos cirúrgico e adjuvante, com duração de oito semanas. Para avaliação da qualidade de vida utilizou-se o questionário WHOQOL-bref. A avaliação clínico funcional foi composta por avaliação: da amplitude de movimento (ADM de ombro mensurada por meio de goniometria; da força muscular de flexão, extensão e abdução de ombro avaliada com uma repetição máxima; da dor

  15. As práticas do cuidar na oncologia: a experiência da fisioterapia em pacientes com câncer de mama Care practice in oncology: the physical therapy experience with breast cancer patients

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    Lina Faria

    2010-07-01

    Full Text Available A fisioterapia oncológica precoce vem desempenhando um importante papel na prevenção e minimização dos efeitos adversos do tratamento do câncer de mama, que acomete um grande número de mulheres. A fisioterapia reduz os riscos de complicações e pode restaurar a integridade cinético-funcional de órgãos e sistemas. A fisioterapia oncológica, ao enfatizar os caminhos da prevenção, tem ampliado a atuação do fisioterapeuta e consolidado seu espaço legítimo no campo médico, complementando as habilidades e competências adquiridas nos últimos anos. A prevenção de problemas e a promoção da saúde estão hoje entre as principais atribuições do fisioterapeuta e devem estar presentes em todas as fases do câncer de mama, do diagnóstico ao tratamento e aos cuidados paliativos.Early oncology physical therapy has played a vital role in preventing and minimizing the side effects of treatment for breast cancer, a disease that strikes a large number of women. Physical therapy reduces the risks of complications and can restore the kinetic and functional integrity of organs and systems. With this emphasis on means of prevention, oncology physical therapy has expanded the professional activities of physical therapists and added to their required skill set in recent years, thereby reinforcing the field's legitimate space within medicine. One of a physical therapist's main duties today is to prevent problems and promote good health, and this service should be offered during all phases of breast cancer, from diagnosis through treatment and palliative care.

  16. Novas diretrizes na abordagem clínica da neutropenia febril e da sepse em oncologia pediátrica New guidelines for the clinical management of febrile neutropenia and sepsis in pediatric oncology patients

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    Ana Verena Almeida Mendes

    2007-05-01

    Full Text Available OBJETIVOS: Fornecer subsídios à abordagem diagnóstica, profilática e terapêutica da neutropenia febril e da sepse em criança com doença oncológica, dando especial atenção aos novos protocolos e diretrizes. FONTES DE DADOS: Revisão de literatura científica utilizando uma busca bibliográfica eletrônica nas páginas do MEDLINE, Medscape, SciELO, Google, Cochrane e PubMED com as palavras-chave febrile, neutropenic, cancer, children, sepse, intensive, care. Foram selecionados artigos publicados entre 1987 e 2007, preferencialmente artigos de revisão, protocolos, revisões sistemáticas, estudos epidemiológicos, recomendações de força-tarefa e ensaios clínicos fase III. Foram revistos os consensos publicados pela Infectious Diseases Society of America, Center for Diseases Control e Infectious Diseases Working Party da German Society of Hematology and Oncology, além de recomendações da World Federation of Pediatric Intensive and Critical Care Societies e da Society of Critical Care Medicine. SÍNTESE DOS DADOS: A utilização de esquemas quimioterápicos agressivos, transplante de medula óssea e recursos de terapia intensiva aumentaram a sobrevida nas crianças com câncer e também a morbidade infecciosa, sendo as complicações sépticas a principal causa de mortalidade. Diversos fatores de risco têm sido identificados, como neutropenia, tipo oncológico, sinais clínicos e marcadores de resposta inflamatória (reação em cadeia da polimerase, procalcitonina, assim como a maior resistência aos antimicrobianos e antifúngicos. Protocolos de classificação de risco, de diagnóstico e tratamento devem ser estabelecidos em cada serviço, respeitando a flora microbiológica da população estudada. A terapia intensiva pediátrica tem aumentado a sobrevida a curto e longo prazo nestes pacientes. CONCLUSÕES: Pacientes oncológicos são particularmente vulneráveis a complicações infecciosas. A identificação e o tratamento

  17. Aborto espontâneo e toxoplasmose ocular em um casal infectado com Toxoplasma gondii = Spontaneous abortion and ocular toxoplasmosis in a couple infected with Toxoplasma gondii

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    Souza, Carla Zangari de

    2015-01-01

    Full Text Available Objetivos: Relatar os casos de um casal, em que a esposa apresentou toxoplasmose na gestação e o esposo, após 15 anos, foi diagnosticado com toxoplasmose ocular. Relato dos casos: Gestante, grávida de gêmeos, residente de um estado na região Sul do Brasil. No primeiro mês de gestação apresentou sorologia não reagente para IgG e IgM anti-Toxoplasma gondii. Na sétima semana de gestação houve soroconversão (IgM e IgG anti-T. gondii reagentes e aborto natural. O esposo, após 15 anos desde o episódio da esposa, queixou-se de visão embaçada/irritada. O exame de fundoscopia revelou lesões típicas de coriorretinite recidivante por toxoplasmose no olho direito. Os exames sorológicos foram IgG anti-T. gondii reagente e IgM anti-T. gondii não reagente. Conclusões: Este relato, de um casal com desfechos clínicos importantes de toxoplasmose, em diferentes formas, enfatiza a relevância do problema da toxoplasmose, que nas suas diversas manifestações, pode trazer graves consequências para a vida de uma família

  18. Acometimento ocular em pacientes com AIDS e toxoplasmose do sistema nervoso central: antes e depois do HAART Ocular involvement in AIDS patients with central nervous system toxoplasmosis: before and after HAART

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    Moysés Zajdenweber

    2005-12-01

    Full Text Available OBJETIVO: Descrever o comprometimento ocular em pacientes com AIDS e toxoplasmose do sistema nervoso central, comparando os períodos pré e pós-terapia anti-retroviral (HAART. MÉTODOS: Em estudo retrospectivo, comparamos 118 pacientes com AIDS e toxoplasmose do sistema nervoso central que foram examinados em nossa instituição antes do pré e pós-terapia anti-retroviral (1994-1996 com 24 pacientes com AIDS e toxoplasmose do sistema nervoso central que foram tratados com pré e pós-terapia anti-retroviral (1996-1999. Todos os pacientes foram submetidos a exame oftalmológico completo e a testes específicos para confirmar o diagnóstico e não houve interseção entre os grupos. RESULTADOS: No grupo pré e pós-terapia anti-retroviral, foi encontrado 23% de toxoplasmose ocular entre os pacientes com toxoplasmose do sistema nervoso central. O envolvimento ocular foi bilateral em 37% dos casos. No grupo dos pacientes que receberam pré e pós-terapia anti-retroviral, que tinham CD4 médio de 256 cel/mm³ e carga viral média de 52.620 cópias, 16,6% apresentaram concomitantemente toxoplasmose ocular e toxoplasmose do sistema nervoso central. O envolvimento ocular foi bilateral em 50% dos casos. CONCLUSÃO: Pacientes com AIDS e toxoplasmose do sistema nervoso central apresentam freqüente associação com toxoplasmose ocular. Embora a incidência de infecções oportunistas tenha diminuído desde a introdução de pré e pós-terapia anti-retroviral, a toxoplasmose ocular continua sendo freqüente em pacientes com toxoplasmose do sistema nervoso central.PURPOSE: To describe the ophthalmologic involvement in patients with Acquired Immunodeficiency Syndrome - AIDS and central nervous system toxoplasmosis comparing the period before and after highly active antiretroviral therapy (HAART. METHODS: In a retrospective study, we compared 118 Acquired Immunodeficiency Syndrome patients with central nervous system toxoplasmosis who were examined at our

  19. Toxoplasmose ocular em cães jovens inoculados com Toxoplasma gondii Ocular toxoplasmosis in young dogs inoculated with Toxoplasma gondii

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    Cláudia Bonini de Abreu

    2002-10-01

    Full Text Available A toxoplasmose é uma doença zoonótica de distribuição mundial que pode infectar uma grande variedade de espécies animais e o homem. No presente trabalho, foram avaliados nove cães jovens inoculados experimentalmente com três cepas diferentes de T. gondii em que se observaram através de microscopia direta e indireta, alterações oftálmicas em sete deles, confirmadas através de retinografia e histopatologia. Com os resultados obtidos, observou-se que as alterações oftálmicas na toxoplasmose adquirida nos cães apareceram já ao término da terceira semana pós-inoculação, mostrando a precocidade das alterações. No exame direto do olho, sete cães apresentaram áreas de hiperrefletividade. Alterações como papiledema, exsudato peripapilar e diminuição da pigmentação do tapetum foram observadas em três cães submetidos à retinografia. O exame histopatológico revelou a presença de discreto infiltrado mononuclear na córnea na região subepitelial em estroma conjuntivo em nível do ângulo da íris, congestão vascular da coróide e edema sub-retiniano em oito cães. Nossos resultados permitem concluir que a toxoplasmose ocular adquirida nos cães é tão significativa quanto na espécie humana. Assim, estudos devem ser aprofundados nesta linha de pesquisa para reforçar os achados.Toxoplasmosis is a zoonotic disease of worldwide distribution that can infect a great variety of animal species and man. In the present study nine young dogs inoculated with three different samples of Toxoplasma gondii were evaluated. Seven of them showed ophthalmic alterations by means of direct and indirect microscopy, photomicrograph and histopathology. From the results obtained it was noted that ophthalmic alterations were already present at the end of the third week after inoculation, showing the precocity of such alterations. In the direct examination of the eyes, seven dogs presented increased reflective areas. Alterations such as

  20. Tratamento conservador em retinoblastoma intra-ocular Conservative treatment for intraocular retinoblastoma

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    Clélia Maria Erwenne

    2003-12-01

    Full Text Available OBJETIVO: Relatar os índices de conservação do globo ocular após tratamento com carboplatina e laser associados ou não a outras formas de tratamento local e radioterapia quando necessário. MÉTODO: Os olhos, virgens de qualquer tratamento, foram inicialmente estadiados, por oftalmoscopia indireta sob narcose ambulatorial, segundo Reese & Ellsworth e os pacientes submetidos à avaliação clínica por pediatra oncologista. Iniciou-se a administração do primeiro ciclo de quimioterapia com carboplatina 200 mg/m², vincristina 1,5 mg/m² e etoposida 150 mg/m² por via endovenosa em 3 dias. Seguiram-se outros ciclos sendo o intervalo entre eles de 21 a 28 dias. De 7 a 15 dias do término do ciclo de quimioterapia, nova oftalmoscopia indireta sob narcose ambulatorial era realizada com descrição dos achados e aplicação de hipertermia por laser Diodo 810 nm, pulso contínuo, e "large spot". O procedimento (quimioterapia e laser foi repetido até completa cicatrização total das lesões ou até que se observasse necessidade de outra modalidade terapêutica como a radioterapia ou a enucleação. Controles periódicos bimensais no primeiro ano e trimestrais nos seguintes foram realizados para reavaliação e tratamento de novas lesões ou recidivas. Acompanhamento clínico por oncologista pediatra foi realizado durante todo o tratamento e seguimento. RESULTADOS: Foram tratados 62 pacientes portadores de RB (32M/30F, 15 unilaterais e 47 bilaterais (total de 107 olhos. A média de idade foi 16,9 meses (2,6 a 71,4. Em 5 pacientes administrou-se 4 ciclos de quimioterapia, nos demais foram necessários mais que 4 e até 8 ciclos. Em 34 olhos não se pode evitar o uso de radioterapia. O tempo médio de seguimento foi de 26,8 meses (5 a 60. Entre os bilaterais os índices de conservação, segundo os estádios de Reese & Ellsworth foram: I 10/11 (90,9%; II 8/9 (88,8%; III 10/10 (100,0%; IV 3/8 (37,5%; V 14/54 (25,9%. Considerando-se o total de

  1. Morte digna da criança: percepção de enfermeiros de uma unidade de oncologia

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    Luise Felix de Souza

    2013-02-01

    Full Text Available O objetivo deste estudo foi identificar o significado e as intervenções de enfermeiros que atuam em oncologia pediátrica na promoção de morte digna da criança. Utilizaram-se como referencial teórico e metodológico o interacionismo simbólico e a pesquisa de narrativa. Os dados foram coletados junto a oito enfermeiros de uma unidade de oncologia pediátrica de um hospital público de São Paulo, por meio de entrevistas semiestruturadas. A análise dos dados permitiu a identificação de cinco categorias: sentir-se sem autonomia para a tomada de decisão; cuidar da família; oferecer conforto físico; valorizar o cuidado humanizado e aprender a lidar com a morte e o morrer. Este estudo contribui para ampliar a compreensão do processo de cuidar e permite avançar na postulação de um quadro teórico que contemple a integração de saberes e ações que constituem uma assistência integral, transcendendo o atendimento de necessidades apenas clínicas e biológicas.

  2. The importance of communication in pediatric oncology palliative care: focus on Humanistic Nursing Theory Importancia de la comunicación en los cuidados paliativos en oncología pediátrica: un enfoque en la Teoría Humanística de Enfermería Importância da comunicação nos cuidados paliativos em oncologia pediátrica: enfoque na Teoria Humanística de Enfermagem

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    Jael Rúbia Figueiredo de Sá França

    2013-06-01

    en el niño con cáncer y es de suma importancia para la promoción de los cuidados paliativos cuando fundamentada en la Teoría Humanística de Enfermería. OBJETIVO: investigar e analisar a comunicação nos cuidados paliativos em oncologia pediátrica, sob o ponto de vista de enfermeiros, com base na Teoria Humanística de Enfermagem. MÉTODO: trata-se de pesquisa de campo, com abordagem qualitativa, da qual participaram dez enfermeiros atuantes em oncologia pediátrica, de um hospital público brasileiro. Para a coleta dos dados, foi utilizada a técnica de entrevista semiestruturada. Os depoimentos foram analisados qualitativamente, à luz da Teoria Humanística de Enfermagem, e nas cinco fases da Enfermagem Fenomenológica. RESULTADOS: da análise do material empírico do estudo, emergiram duas categorias temáticas: "estratégia para humanizar o cuidar em enfermagem, com ênfase no alívio do sofrimento da criança" e "estratégia para fortalecer o vínculo de confiança entre enfermeiro e criança". CONCLUSÃO: a comunicação se configura como um elemento eficaz no cuidado com a criança com câncer e é de suma importância para a promoção dos cuidados paliativos quando alicerçada na Teoria Humanística de Enfermagem.

  3. Achados oculares e fundoscópicos em pacientes com lupus eritematoso sistêmico Ocular and fundoscopic findings in patients with systemic lupus erythematosus

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    Silvane Bigolin

    2000-10-01

    Full Text Available Objetivos: Descrever as alterações encontradas no exame ocular de pacientes com lupus eritematoso sistêmico (LES, especialmente aquelas relacionadas à fundoscopia. Método: Estudo descritivo de 41 pacientes lúpicos, selecionados aleatoriamente entre maio e julho de 1999 no ambulatório de colagenoses do Serviço de Reumatologia do Hospital de Clínicas da Universidade Federal do Paraná. Foi aplicado um protocolo de avaliação clínica e ocular. Resultados: Foram incluídos no estudo 41 pacientes, sendo 40 (97,56% do sexo feminino e 01 (2,44% do sexo masculino. A média de idade foi de 32,22 anos, com mínima de 16 e máxima de 54 anos. Trinta e seis pacientes (87,80% eram de cor branca, dois (4,89% de cor negra e três (7,32% pardos. O tempo de diagnóstico de LES variou de dois meses a 18 anos. Dos 41 pacientes, 19 (46,34% apresentaram alteração fundoscópica relacionada ao LES. As principais lesões encontradas foram manchas algodonosas e estreitamento arteriolar (68,42%, seguidas de aumento da escavação (10,52% e palidez do disco óptico (10,52%, lesão perivascular (5,26% e alteração no epitélio pigmentar da retina (5,26%. Conclusão: Observou-se alta prevalência de alterações fundoscópicas relacionadas ao LES, demonstrando a importância de exames fundoscópicos regulares mesmo em pacientes lúpicos assintomáticos ou sem doenças associadas.Purpose: To describe the changes in ocular examination of patients with systemic lupus erythematosus (SLE, especially those related to fundoscopy. Method: A descriptive study of 41 lupus patients selected at random from May to July 1999 at the Collagen Disease Outpatient Clinic of the Rheumatology Service of the University Hospital, Federal University of Paraná. A protocol of clinical and ophthalmologic evaluation was applied. Results: Forty-one patients were included in the study; 40 were females (97.56% and one was a male (2.44%. Mean age was 32.22 years (range: 16 to 54 years

  4. Ocular Hypertension

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Ocular Hypertension Sections What Is Ocular Hypertension? Ocular Hypertension Causes ... Hypertension Diagnosis Ocular Hypertension Treatment What Is Ocular Hypertension? Leer en Español: ¿Qué Es la Hipertensión Ocular? ...

  5. Ocular Melanoma

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Ocular Melanoma Sections What is Ocular Melanoma? Ocular Melanoma Causes ... Melanoma Diagnosis Ocular Melanoma Treatment What is Ocular Melanoma? Leer en Español: ¿Qué Es el Melanoma Ocular? ...

  6. Injeção subconjuntival de soro autógeno no tratamento de queimadura ocular por álcali em coelhos Subconjunctival injection of autogenous blood in the treatment of ocular alcali burn in rabbits

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    Marcela Colussi Cypel

    2004-10-01

    Full Text Available OBJETIVO: Estudar a ação da injeção subconjuntival de soro autógeno na evolução das complicações, após queimadura ocular grave por álcali induzida experimentalmente em coelhos. MÉTODOS: Foram utilizados trinta olhos de coelhos da raça Nova Zelândia, divididos em dois grupos, de 15 coelhos cada, ambos submetidos à queimadura grave por álcali. Em 15 olhos (grupo tratado, efetuamos, imediatamente após a queimadura, injeção de soro autógeno subconjuntival. Os resultados foram avaliados e comparados logo após a queimadura e nos dias 1, 3, 7, 15 e 30 por meio de ectoscopia biomicroscopia ocular. RESULTADOS: O grupo tratado apresentou melhor resposta de reepitelização da córnea, na fase inicial do processo do que o grupo controle (grupo sem soro autógeno, diferença esta estaticamente significante, assim como resultado final com um menor número de complicações. CONCLUSÃO: Os resultados obtidos neste estudo experimental sugerem que soro autógeno pode ter efeito no processo de cicatrização dos olhos após queimadura alcalina, diminuindo complicações tardias e melhorando o prognóstico quanto à estabilidade do processo inflamatório cicatricial.PURPOSE: To determine the activity of subconjunctival injection of autogenous serum in the treatment of ocular alkali burn induced experimentally in rabbits. METHODS: Thirty eyes of 30 New Zeland albino rabbits were divided into two groups of 15 and submitted to ocular alkali burn. One group (treated group received immediately after the alkali burn a subconjunctival injection of autogenous serum. The results were compared and recorded immediately after the alkali burn and on days 1, 3, 7, 15, and 30 by external ocular examination and manual portable slit lamp. RESULTS: The treated group presented a better reepithelialization of the cornea than the control group, in the beginning of the process, with a statistically significant difference; and a final result with less complications

  7. Evaluation of the sensitivity and specificity of criteria for isolation of patients admitted to a specialized cancer hospital Evaluación de la sensibilidad y especificidad de los criterios para aislamiento de pacientes admitidos en un hospital especializado en oncología Avaliação da sensibilidade e da especificidade dos critérios para isolamento de pacientes admitidos em um hospital especializado em oncologia

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    Caroline Cataneo

    2011-10-01

    los pacientes colonizados fue aislada en el momento de la admisión. La sensibilidad de los criterios para aislamiento fue de 90% y la especificidad de 6,5%.O isolamento precoce de pacientes, possivelmente colonizados por microrganismos multirresistentes, pode minimizar sua disseminação, reduzindo os casos de infecção hospitalar e os custos associados. O objetivo deste estudo foi identificar a sensibilidade e especificidade dos critérios para isolamento de pacientes admitidos num hospital especializado em oncologia. Como método, usou-se o estudo transversal. A população foi composta por 61 pacientes, admitidos no período de 1º março a 31 de agosto de 2009, e procedentes de outros hospitais. Foi preenchido instrumento de coleta de dados no momento da admissão e colhidas amostras da região nasal e anal para cultura microbiológica. Os resultados mostraram que, dos 56 pacientes que preencheram os critérios de isolamento, 30 (49,2% tiveram culturas positivas para microrganismos multirresistentes e o Staphylococcus aureus resistente à oxacilina foi o mais frequentemente identificado. A maioria dos pacientes colonizados foi isolada no momento da admissão. Conclui-se que a sensibilidade dos critérios para isolamento foi de 90% e a especificidade de 6,5%.

  8. Percepção de autoinstilação de gotas oculares em idosos com ou sem dispositivo de apoio facial

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    Arlindo Jose Freire Portes

    Full Text Available RESUMO Objetivo: Determinar o grau de dificuldade para instilação tópica ocular em idosos, com ou sem o auxílio de dispositivo de apoio facial, por meio de questionário. Observar qual método foi tecnicamente melhor para aplicação tópica ocular de gotas. Métodos: O estudo foi um ensaio clínico, controlado, randomizado e pareado, realizado em 50 pacientes idosos de setembro de 2015 a junho de 2016 na Policlínica Ronaldo Gazolla, Lapa-Rio de Janeiro. Um frasco de colírio Optive® foi acoplado ao dispositivo de apoio facial denominado Eyedrop®. Cada participante instilou o colírio com ou sem o auxílio do dispositivo em cada um dos olhos, sendo que a seleção ocular foi feita aleatoriamente. Foi perguntado ao paciente questões pré-formuladas sobre a dificuldade de ambos os métodos e a técnica de administração tópica ocular foi avaliada. Resultados: A instilação de gotas foi considerada difícil ou muito difícil por 10% dos idosos com o auxílio do dispositivo e por 36% sem o auxílio (p = 0,0047. Houve toque da ponta do colírio com os tecidos oculares em 64% dos pacientes que não usaram o Eyedrop® e em 4% dos que o utilizaram (p=0,000001. A maior dificuldade descrita na instilação tradicional foi acertar o olho com a gota (32% e com o dispositivo de apoio foi entender seu uso(4%. Conclusão: A maioria dos idosos instila colírios erroneamente, tocando a ponta do frasco em tecidos oculares, o que favorece sua contaminação. O dispositivo de apoio facial tornou mais segura e fácil a instilação.

  9. Lista de recomendações do Exame PET/CT com 18F-FDG em Oncologia: consenso entre a Sociedade Brasileira de Cancerologia e a Sociedade Brasileira de Biologia, Medicina Nuclear e Imagem Molecular Recommendations on the use of 18F-FDG PET/CT in Oncology: consensus between the Brazilian Society of Cancerology and the Brazilian Society of Biology, Nuclear Medicine and Molecular Imaging

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    José Soares Junior

    2010-08-01

    Full Text Available Apresentamos uma lista de recomendações sobre a utilização de 18F-FDG PET em oncologia, no diagnóstico, estadiamento e detecção de recorrência ou progressão do câncer. Foi realizada pesquisa para identificar estudos controlados e revisões sistemáticas de literatura composta por estudos retrospectivos e prospectivos. As consequências e o impacto da 18F-FDG PET no manejo de pacientes oncológicos também foram avaliados. A 18F-FDG PET deve ser utilizada como ferramenta adicional aos métodos de imagem convencionais como tomografia computadorizada e ressonância magnética. Resultados positivos que sugiram alteração no manejo clínico devem ser confirmados por exame histopatológico. A 18F-FDG PET deve ser utilizada no manejo clínico apropriado para o diagnóstico de cânceres do sistema respiratório, cabeça e pescoço, sistema digestivo, mama, melanoma, órgão genitais, tireoide, sistema nervoso central, linfoma e tumor primário oculto.The authors present a list of recommendations on the utilization of 18F-FDG PET/CT in oncology for the diagnosis, staging and detection of cancer, as well as in the follow-up of the disease progression and possible recurrence. The recommendations were based on the analysis of controlled studies and a systematic review of the literature including both retrospective and prospective studies regarding the clinical usefulness and the impact of 18F-FDG PET/CT on the management of cancer patients. 18F-FDG PET/CT should be utilized as a supplement to other conventional imaging methods such as computed tomography and magnetic resonance imaging. Positive results suggesting changes in the clinical management should be confirmed by histopathological studies. 18F-FDG PET should be utilized in the diagnosis and appropriate clinical management of cancer involving the respiratory system, head and neck, digestive system, breast, genital organs, thyroid, central nervous system, besides melanomas, lymphomas and

  10. Alterações oculares em paciente pediátrico portador de malformações de Dandy-Walker: relato de caso

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    Ewald Oscar

    2006-01-01

    Full Text Available Descreveremos um caso raro de malformações da síndrome de Dandy-Walker e suas alterações oculares. Trata-se de criança do sexo feminino, com idade de 1 ano e 9 meses, que apresentava alterações no sistema nervoso central (síndrome de Dandy-Walker, associado à baixa acuidade visual, megalocórnea (diâmetro de 13 mm no olho direito e 13,5 mm no olho esquerdo, escavação de 0,7 em ambos os olhos (AO e palidez temporal de papila óptica de AO, pressão intra-ocular de 16 mmHg no olho direito e 14 mmHg no olho esquerdo e diâmetro antero-posterior de 20,55 mm em ambos os olhos.

  11. Diversão em movimento: um projeto lúdico para crianças hospitalizadas no Serviço de Oncologia Pediátrica do Instituto Materno Infantil Prof. Fernando Figueira, IMIP Ludotherapy for hospitalized children: a ludotherapy program for hospitalized children in the Pediatrics Oncology Unit of the Instituto Materno Infantil Prof. Fernando Figueira, IMIP

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    Arli Melo Pedrosa

    2007-03-01

    Full Text Available O presente trabalho descreve as atividades lúdicas desenvolvidas na enfermaria de oncologia pediátrica do Instituto Materno Infantil Prof. Fernando Figueira (IMIP, com 60 pacientes portadores de neoplasias malignas, no período de janeiro de 2004 a janeiro de 2005. Descreve também as etapas do Projeto e apresenta os resultados obtidos, correlacionando as etapas do desenvolvimento da aprendizagem com os instrumentos lúdicos utilizados como recurso minimizador do processo de hospitalização, através dos itens mais solicitados, considerando, para essa análise, as idéias de Jean Piaget e Bruno Bettelheim.This paper describes a ludotherapy program implemented in the pediatrics oncology ward of the Instituto Materno Infantil Prof. Fernando Figueira (IMIP with 60 malignant neoplasia patients from January 2004 to January 2005. It describes the phases of the project, demonstrates results obtained, relating learning development phases and ludic tools used as a resource to mitigate hospitalization hardships through the most requested items. Jean Piaget and Bruno Bettelheim concepts were used in this assessment.

  12. Ocular changes due to systemic alpha-interferon therapy for hepatitis C Alterações oculares por uso sistêmico de alfa-interferon em pacientes com hepatite C

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    Liang Shih Jung

    2004-12-01

    Full Text Available PURPOSE: To describe ocular (specially fundoscopic changes due to systemic alpha-interferon (IFN therapy in patients with hepatitis C. This is a prospective, descriptive and observational (non-interventional study, and its results are preliminary. METHODS: Patients were selected with indication of alpha-interferon therapy for hepatitis C. They underwent ocular examinations before therapy and 1, 3, 6 and 12 months after starting the therapy. HIV patients and those who had a history of previous treatment with alpha-interferon were excluded from the study, but examined. RESULTS: Fifty-one patients were selected from November 1999 to June 2000. The male-to-female ratio was 1.55. The age average was 47 years. The best corrected visual acuity ranged from 20/15 to 20/40. Most of the symptomatic patients complained of foreign body sensation in the eyes, which became more tolerable with time. Complaints comprised flu-like symptoms, joint pain, depression, headache, and general weakness. Ocular findings related to alpha-interferon were: cotton wool spots (3 eyes and intraretinal hemorrhage (1 eye. One patient died during the study, due to another disease not related to hepatitis, and one patient refused to be examined. CONCLUSIONS: There are retinal vascular changes due to systemic alpha-interferon for hepatitis C. There are no studies in our country describing ocular changes in patients with hepatitis C on therapy with alpha-interferon. General physicians and specially gastroenterologists should pay special attention to this problem, and refer these patients to the ophthalmologist in order to determine and follow any lesion that may be related to the use of this drug.OBJETIVO: Avaliar alterações oculares (em especial lesões fundoscópicas em pacientes com hepatite C tratados com alfa-interferon (IFN. MÉTODOS: Estudo prospectivo, descritivo e observacional de pacientes com hepatite C do serviço de Gastroenterologia da UNIFESP com indicações de uso

  13. Análise da distribuição espacial de dose absorvida em próton terapia ocular Spatial distribution analysis of absorbed dose in ocular proton radiation therapy

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    Marília Tavares Christóvão

    2010-08-01

    Full Text Available OBJETIVO: Propõe-se avaliar os perfis de dose em profundidade e as distribuições espaciais de dose para protocolos de radioterapia ocular por prótons, a partir de simulações computacionais em código nuclear e modelo de olho discretizado em voxels. MATERIAIS E MÉTODOS: As ferramentas computacionais empregadas foram o código Geant4 (GEometry ANd Tracking Toolkit e o SISCODES (Sistema Computacional para Dosimetria em Radioterapia. O Geant4 é um pacote de software livre, utilizado para simular a passagem de partículas nucleares com carga elétrica através da matéria, pelo método de Monte Carlo. Foram executadas simulações computacionais reprodutivas de radioterapia por próton baseada em instalações pré-existentes. RESULTADOS: Os dados das simulações foram integrados ao modelo de olho através do código SISCODES, para geração das distribuições espaciais de doses. Perfis de dose em profundidade reproduzindo o pico de Bragg puro e modulado são apresentados. Importantes aspectos do planejamento radioterápico com prótons são abordados, como material absorvedor, modulação, dimensões do colimador, energia incidente do próton e produção de isodoses. CONCLUSÃO: Conclui-se que a terapia por prótons, quando adequadamente modulada e direcionada, pode reproduzir condições ideais de deposição de dose em neoplasias oculares.OBJECTIVE: The present study proposes the evaluation of the depth-dose profiles and the spatial distribution of radiation dose for ocular proton beam radiotherapy protocols, based on computer simulations in nuclear codes and an eye model discretized into voxels. MATERIALS AND METHODS: The employed computational tools were Geant4 (GEometry ANd Tracking Toolkit and SISCODES (Sistema Computacional para Dosimetria em Radioterapia - Computer System for Dosimetry in Radiotherapy. Geant4 is a toolkit for simulating the passage of particles through the matter, based on Monte Carlo method. Computer simulations

  14. Opacificação tipo "snowflake" em lente intra-ocular de polimetilmetacrilato (PMMA)

    OpenAIRE

    Pereira,Fabiana Dalla Rosa; Lima,Vagner Loduca; Rehder,José Ricardo Carvalho Lima

    2011-01-01

    As lentes intraoculares têm sido utilizadas na reabilitação de pacientes submetidos à cirurgia de catarata desde 1959 com grande sucesso. Entretanto, alterações no biomaterial dessas lentes vêm sendo descritas nos últimos anos, diminuindo a acuidade visual dos pacientes anos depois da cirurgia. Este relato apresenta um caso de opacificação tipo "snowflake" em lente de polimetilmetacrilato, seguida de discussão sobre as principais características dessa alteração e indicação de retirada e troca...

  15. Opacificação tipo "snowflake" em lente intra-ocular de polimetilmetacrilato (PMMA

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    Fabiana Dalla Rosa Pereira

    2011-04-01

    Full Text Available As lentes intraoculares têm sido utilizadas na reabilitação de pacientes submetidos à cirurgia de catarata desde 1959 com grande sucesso. Entretanto, alterações no biomaterial dessas lentes vêm sendo descritas nos últimos anos, diminuindo a acuidade visual dos pacientes anos depois da cirurgia. Este relato apresenta um caso de opacificação tipo "snowflake" em lente de polimetilmetacrilato, seguida de discussão sobre as principais características dessa alteração e indicação de retirada e troca da lente intraocular.

  16. Miopatia ocular descendente Descending ocular myopathy

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    Nunjo Finkel

    1972-06-01

    Full Text Available São relatados 4 casos de miopatia ocular descendente (MOD com história familial levantada em três gerações. Biópsia musculares e eletromiografia em um caso confirmaram o caráter miogênico da doença. A MOD nada mais seria do que uma forma clínica especial de distrofia muscular, de início tardio.Four cases of the so-called descending ocular myopathy with a family history in three generations are reported. In the first case muscular biopsy and electromyographic studies proved the myogenic nature of the process. Descending ocular myopathy seems to be just a clinical form of muscular distrophy of late onset.

  17. Prevalência de manifestações oculares em 198 pacientes com artrite reumatóide: um estudo retrospectivo Prevalence of ocular manifestation in 198 patients with rheumatoid arthritis: a restrospective study

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    Raphael Guimarães Bettero

    2008-06-01

    Full Text Available OBJETIVO: Estimar a prevalência de manifestações oculares na população local de artrite reumatóide (AR. Estimar se a presença de auto-anticorpos como fator reumatóide (FR e fator antinuclear (FAN influi no aparecimento destas manifestações e se existe associação entre o aparecimento de manifestações oculares e índice funcional do paciente, idade ao diagnóstico e tempo de doença. MÉTODOS: Foram estudados retrospectivamente 198 prontuários de pacientes com AR, acompanhados durante o período de 2003 a 2006. Avaliou-se a prevalência das manifestações oftalmológicas, perfil de auto-anticorpos, dados demográficos e índice funcional de Steinbrock destes pacientes. RESULTADOS: Síndrome de Sjögren secundária apareceu em 12,1% dos pacientes sendo mais comum em mulheres (p=0,049 e em pacientes com maior dano articular (p=0,016. Ceratite ulcerativa e esclerite incidiram em torno de 2% dos pacientes. Fator reumatóide (FR e fator antinuclear (FAN assim como tempo de doença e idade do paciente ao diagnóstico não influíram no aparecimento das manifestações estudadas. CONCLUSÃO: A síndrome de Sjögren secundária é a manifestação ocular mais prevalente em pacientes com AR, sendo mais comum em mulheres e em pacientes com mais disfunção articular.PURPOSE: To study the prevalence of eye manifestations in the local rheumatoid arthritis (RA population, as well as to know if the presence of rheumatoid factor (RF and antinuclear antibodies (ANA affect this profile. To study if there is association between eye manifestations and patient's articular functional index, age at diagnosis and illness duration. METHODS: We reviewed 198 charts of rheumatoid arthritis patients followed-up from 2003 to 2006. They were studied for: prevalence of ophthalmologic manifestations, autoantibody profile, demographic data and Steinbrock's functional index. RESULTS: Secondary Sjögren's syndrome was seen in 12.1% of the patients being more common

  18. Avaliação dos comprometimentos oculares em hansenianos virgens de tratamento

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    Bárbara Celeste Rolim

    1991-09-01

    Full Text Available Foram avaliados através da consulta de enfermagem em prevenção oftalmológica no Hospital Estadual Curupaiti, RJ, 108 hansenianos virgens de tratamento afim de detectar o nível de comprometimento do aparelho visual, no início do tratamento clínico. Diversos foram os comprometimentos detectados, como diminuição da produção de lágrimas, paresia do músculo orbicular da pálpedra, diminuição da sensibilidade corneal e pterígio. Percebemos que a prevalência aumenta na dependência direta de fatores como: idade, forma clínica e tempo de doença. A partir desta situação, enfatiza-se a necessidade de avaliação sistemática e rotineira do aparelho visual pelos profissionais de saúde que atuam no programa de controle da endemia. Propomos que o enfermeiro assuma esta atividade, propiciando, assim atuação direta na assistência e abrindo novo campo de atuação para a categoria.

  19. Intraocular pressure in schizophrenic patients treated with psychiatric medications Pressão intra-ocular em pacientes esquizofrênicos tratados com medicações psiquiátricas

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    Valéria Barreto Novais e Souza

    2008-10-01

    Full Text Available PURPOSE: In order to assess the occurrence of adverse ocular effects of antipsychotic drugs, we sought to evaluate intraocular pressure of schizophrenic patients treated with psychiatric medications. METHODS: Twenty-eight outpatients with DSM-IV diagnosis of schizophrenia who met both the inclusion and exclusion criteria were submitted to an ophthalmic evaluation for ocular abnormalities which included intraocular pressure measurement with Goldmann applanation tonometry. RESULTS: Raised intraocular pressure was found in three patients (11%. Abnormality in cup-disc ratio was seen in only one patient with cup-disc ratio asymmetry of 0.4. All these four patients were taking only ziprasidone. CONCLUSIONS: Patients using ziprasidone were found to have abnormalities in both intraocular pressure and cup-disc ratio.OBJETIVO: Para avaliar a ocorrência de efeitos adversos oculares dos antipsicóticos, buscamos avaliar a pressão intra-ocular em pacientes esquizofrênicos tratados com medicações psiquiátricas. MÉTODOS: Vinte e oito pacientes tratados ambulatorialmente com diagnóstico de esquizofrenia segundo o DSM-IV que preencheram os critérios de inclusão e exclusão foram submetidos a uma avaliação oftalmológica para pesquisa de alterações oculares que incluiu a medida da pressão intra-ocular com tonometria de aplanação de Goldmann. RESULTADOS: Pressão intra-ocular aumentada foi encontrada em 3 pacientes (11%. Anormalidade na escavação do disco óptico foi observada em apenas um paciente com assimetria de escavação de 0,4. Todos esses quatro pacientes estavam usando apenas ziprasidona. CONCLUSÕES: Pacientes em uso de ziprasidona apresentaram anormalidades na pressão intra-ocular e na escavação do disco óptico.

  20. Prótese intra-ocular de resina acrílica em cães e gatos Acrylic resin intraocular prosthesis in dogs and cats

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    S.C. Rahal

    2000-08-01

    Full Text Available Foram atendidos no Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Unesp - Campus de Botucatu, 11 animais (oito cães e três gatos, com alterações oftálmicas unilaterais graves que levaram à perda total da função ocular (protrusão de globo com injúria nervosa e estrutural, perfurações de córnea com perda de conteúdo intra-ocular e endoftalmites, entre outras. Os animais, com idades entre dois meses e 10 anos, foram submetidos à evisceração e posterior inclusão de esfera de resina acrílica (metilmetacrilato na capa córneo-escleral ou escleral. As esferas foram previamente confeccionadas e esterilizadas por autoclavagem. No pós-operatório foram utilizados antiinflamatórios e antibioticoterapia tópica combinada ou não a sistêmica. O período de observação variou de 2 meses a 3 anos e os aspectos avaliados foram secreção ocular, blefarospasmo, sinais de desconforto e estética. Obtiveram-se resultados satisfatórios em oito casos. Concluiu-se que a resina acrílica pode ser uma alternativa para uso como inclusão em cavidade anoftálmica.Eleven animals (eight dogs and three cats, aged between two months and ten years were referred to the Veterinary Hospital of Faculty of Veterinary Medicine and Animal Science - Unesp, Botucatu, Brazil. These animals presented severe unilateral ophthalmic changes that lead to a total loss of ocular function, such as prolapsed eyes with nervous and structural injury, corneal damage with loss of intraocular contents or endophthalmitis among others. They were submitted to evisceration followed by the insertion of an acrylic resin prosthesis (methylmethacrylate in the corneoscleral or scleral shell. The spheres were previously made and sterilized by autoclave. The postoperative medical therapy included topical and systemic broad-spectrum antibiotics for seven days and anti-inflammatory drugs. The follow-up time varied from two months to three years. The evaluated

  1. Prevalência de doenças oculares e causas de comprometimento visual em crianças atendidas em um Centro de Referência em Oftalmologia do centro-oeste do Brasil

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    Maria Nice Araujo Moraes Rocha

    2014-08-01

    Full Text Available Objetivo: Identificar os níveis de comprometimento visual e a prevalência de oftalmopatias e ametropias em crianças atendidas em um centro de referência em oftalmologia do centro-oeste brasileiro. Comparar os achados com dados publicados referentes a outras regiões do Brasil. Métodos: Estudo transversal, descritivo e retrospectivo com análise de prontuários de crianças atendidas no Centro de Referência em Oftalmologia (CEROF da Universidade Federal de Goiás, no período compreendido entre abril de 2009 e março de 2010. Resultados: Foram avaliados 2408 prontuários, sendo 2128 (88,4% de atendimento eletivo e 280 (11,6% de atendimento no setor de urgências do CEROF. Houve predomínio na faixa etária de 6 a 10 anos (44,2%, seguido pela de 11 a 14 anos (29,6%. O exame foi considerado normal em 12,9% (n=274 dos atendimentos eletivos e em 6,8 (n=19 dos atendimentos de urgência. As doenças mais encontradas nas crianças foram as conjuntivites infecciosas (248 casos, 26,4% e alérgicas (204 casos, 21,7%, blefarite (69 casos, 7,3%, calázio (34 casos, 3,6%, estrabismo (133 casos, 12,06%, as doenças de retina e vítreo (24 casos, 2,6%, catarata e alterações de cristalino (20 casos, 2,1%. As ametropias mais frequentes, contadas por olho, foram a hipermetropia (46,9% e o astigmatismo (42,2% e as doenças sistêmicas mais informadas foramprematuridade (30 casos e diabete melito (26 casos. Conclusão: Este estudo identificou as principais causas de doenças oculares em crianças atendidas em um centro universitário de referência. O grupo de doenças mais prevalente foi o das doenças de córnea e conjuntiva (conjuntivites alérgicas, olho seco e ceratites. As doenças de pálpebra ocuparam o segundo lugar (blefarite, calázio, e obstrução de vias lacrimais. As ametropias mais frequentes foram a hipermetropia e o astigmatismo. Os achados na população estudada mostram-se semelhantes aos observados na literatura nacional.

  2. Miopatia ocular descendente

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    Nunjo Finkel

    1972-06-01

    Full Text Available São relatados 4 casos de miopatia ocular descendente (MOD com história familial levantada em três gerações. Biópsia musculares e eletromiografia em um caso confirmaram o caráter miogênico da doença. A MOD nada mais seria do que uma forma clínica especial de distrofia muscular, de início tardio.

  3. Psico-oncologia: história, características e desafios

    OpenAIRE

    Carvalho,Maria Margarida

    2002-01-01

    Este artigo visa oferecer uma visão da Psico-oncologia, através de um resumo da história, do campo de ação e dos problemas específicos da área. Os primeiros estudos da ligação corpo e mente no câncer tiveram início na Grécia, mas esta visão foi abandonada até o século XIX quando Freud voltou a mostrar que o psíquico podia ocasionar processos físicos. A Medicina Psicossomática, a Medicina e a Psicologia Comportamental e a Psicologia da Saúde abriram o caminho para a Psico-Oncologia, hoje muito...

  4. Movimentos oculares e padrões de busca visual em tarefas de rotação mental Eye movements and scan patterns in mental rotation tasks

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    Priscila Covre

    2005-06-01

    Full Text Available O objetivo deste estudo é identificar as estratégias utilizadas nas tarefas de rotação mental pela análise dos traçados dos movimentos oculares. Foi analisado o desempenho de 40 participantes na comparação de pares de objetos tridimensionais rotacionados no eixo y, com diferenças de angulação de 0o a 180o. Foi utilizado um sistema computacional de rastreamento dos movimentos oculares (eyetracking durante a visualização de figuras. Os resultados mostram que tempo de julgamento, duração média das fixações do olho, número de fixações nos objetos e número de alternâncias entre os dois objetos aumentam em função da diferença de angulação. Análise dos traçados oculares, com base na inspeção visual, indica o uso de dois tipos de estratégias: rotação mental em torno dos eixos padrões e comparação independente da orientação. O uso dessas estratégias é discutido com relação ao desempenho dos participantes e à memória de trabalho.The purpose of this paper is to identify the strategies used on mental rotation tasks by analyzing ocular movements. The performance of 40 participants on comparison of pairs of three-dimensional objects, rotated on the y-axis, from 0o to 180o was analyzed. An eye-tracking computerized system was used to track eye movements during scene visualization. Results showed that judgment time, fixation duration, number of fixations and number of switches between the objects increased with rotation angle. Analysis by visual inspection indicates the use of two kinds of strategies: Mental rotation around the standard axis and comparison of orientation-free descriptions. The use of the strategies is discussed with regard to performance and working memory.

  5. Ocular toxoplasmosis with positive polymerase chain reaction in peripheral blood: report of two cases, São Paulo State, Brazil = Toxoplasmose ocular com reação em cadeia da polimerase positiva em sangue periférico: relato de dois casos, estado de São Paulo, Brasil

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    Barbosa, Amanda Pires

    2015-01-01

    Full Text Available Objetivos: Descrever o uso da reação em cadeia da polimerase (PCR no sangue periférico e demonstrar sua importância no acompanhamento clínico de pacientes com toxoplasmose ocular. Descrição dos casos: Dois pacientes imunocompetentes foram clinicamente diagnosticados com toxoplasmose ocular aguda. Rotineiramente, a avaliação clínica foi feita por fundoscopia com o uso de oftalmoscópio binocular indireto, retinografia colorida, angiografia fluorescente e tomografia de coerência óptica espectral. A sorologia foi realizada por ensaio imunoenzimático (ELISA e confirmada por ensaio imunoenzimático fluorescente ELFA (IgG, IgM. O diagnóstico molecular foi realizado por PCR em sangue periférico usando o gene B1 de Toxoplasma gondii como marcador. O paciente mais jovem era do sexo masculino, apresentava lesão prévia no olho direito, queixa de baixa acuidade visual no olho esquerdo e estava sob tratamento. O paciente mais velho era do sexo masculino, apresentava descolamento de retina e súbita diminuição de visão no olho direito. A fundoscopia revelou cicatriz coriorretiniana no olho esquerdo. Ambos os pacientes tinham IgG reagente, IgM não reagente e PCR positivo em sangue periférico. Novas amostras de sangue foram coletadas para monitoramento sorológico e molecular e a PCR permaneceu positiva em ambos os casos. Seis semanas após o início do tratamento com sulfadiazina e pirimetamina oral, os resultados do PCR tornaram-se negativos. Conclusões: Os resultados mostram que antígenos de T. gondii podem ser encontrados em sangue periférico durante as reativações oculares e que a PCR parece ser uma boa ferramenta para o acompanhamento de pacientes com toxoplasmose ocular

  6. Prótese intra-ocular de resina acrílica em cães e gatos

    OpenAIRE

    Rahal,S.C.; F.M.M. Bergamo; Ishiy, H M

    2000-01-01

    Foram atendidos no Hospital Veterinário da Faculdade de Medicina Veterinária e Zootecnia da Unesp - Campus de Botucatu, 11 animais (oito cães e três gatos), com alterações oftálmicas unilaterais graves que levaram à perda total da função ocular (protrusão de globo com injúria nervosa e estrutural, perfurações de córnea com perda de conteúdo intra-ocular e endoftalmites, entre outras). Os animais, com idades entre dois meses e 10 anos, foram submetidos à evisceração e posterior inclusão de esf...

  7. Ilhas sintáticas e plausibilidade semântica – um estudo de rastreamento ocular de frases com lacunas preenchidas em português brasileiro

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    Marcus Antonio Rezende Maia

    2016-08-01

    Full Text Available Este trabalho apresenta um experimento de rastreamento ocular em que se investiga o efeito da lacuna preenchida (ELP em construções subjacentes e não subjacentes e em contextos semânticos de plausibilidade e de implausibilidade. Os resultados sugerem que configurações de ilhas sintáticas são percebidas rapidamente pelo processador, impedindo tanto a postulação do ELP, quanto a avaliação semântica de plausibilidade na seleção-s do complemento pelo verbo. Nas condições não subjacentes, o ELP se instancia e a avaliação semântica ocorre apenas posteriormente às decisões de análise sintática, não evitando o ELP, conforme predito pelos modelos de processamento  do tipo syntax-first. 

  8. Investigation of bacterial microbiota and risk factors in dogs with external ocular diseases from Bandeirantes, Paraná State, BrazilInvestigação da microbiota bacteriana e associações de risco em cães com afecções oculares externas atendidos em Bandeirantes, Paraná, Brasil

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    João Luis Garcia

    2012-02-01

    bilaterais, e 120 cães sem doenças oculares (grupo controle, foram atendidos entre 08/2008 a 07/2009 no Hospital Veterinário da Universidade Estadual do Norte do Paraná. As amostras coletadas do saco conjuntival inferior foram semeadas em ágar sangue e MacConkey e incubadas em aerobiose a 37ºC por até 120 horas. Após a identificação presuntiva, as espécies bacterianas foram identificadas pelos sistemas APISTAPH (bio- Merieux, Inc., API 20 STREP (bio-Merieux, Inc. e BACTRAY (Laborclin, ltda. e semeadas em agar Mueller-Hinton, para determinação da sensibilidade por meio da técnica de difusão de discos. Para as associações de risco, os proprietários dos 158 cães responderam um questionário com variáveis epidemiológicas. Das 63 amostras, houve crescimento de microrganismos em 46 (73,02%, com isolamento de um microrganismo em 42 amostras e de dois microrganismos em quatro. Bactérias Gram positivas corresponderam a 76% dos isolamentos, Gram negativas a 20% e fungos leveduriformes a 4%. Staphylococcus spp totalizaram 66% dos isolamentos, sendo S. aureus (24% e S. intermedius (24% as mais prevalentes. Exceto S. intermedius (91,67% e S. epidermidis (66,67%, as espécies bacterianas isoladas apresentaram resistência de 100% às sulfonamidas. Os S. aureus isolados apresentaram sensibilidade de 91,67% para cloranfenicol, tobramicina e amoxicilina/clavulanato, e o mesmo percentual de resistência para tetraciclina. Os S. intermedius apresentaram 100% de sensibilidade para amoxicilina/clavulanato e 91,67% para gentamicina e resistência de 75% para tetraciclina e ceftriaxona. As associações de risco para as doenças oculares externas foram recidivas clínicas (OR=59,50, 7,29ocular (OR=23,00, 6,80

  9. Ocular lesions in HTLV-1 infected patients from Salvador, State of Bahia: the city with the highest prevalence of this infection in Brazil Lesões oculares em pacientes infectados pelo HTLV-1 em Salvador, Estado da Bahia: a cidade com maior prevalência desta infecção no Brasil

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    Regina Helena Rathsam-Pinheiro

    2009-12-01

    Full Text Available In order to determine the prevalence of ocular lesions in HTLV-1 infected patients in Salvador Bahia, a transversal study was conducted on 140 HTLV-1 infected patients (90 asymptomatic and 50 tropical spastic paraparesis/HTLV-1-associated myelopathy between June 2004 and November 2005. The ophthalmological examination included visual acuity measurement, ocular motility, biomicroscopy of the anterior and posterior chambers, intraocular pressure and evaluation of lachrymal secretion. Observation verified 4 (2.8% out of 140 patients with uveitis (two patients had intermediate uveitis and two had pan-uveitis and 39 (36.4% out of 107 patients with keratoconjunctivitis sicca. The prevalence of Keratoconjunctivitis sicca was significantly higher among the TSP/HAM patients (OR age adjusted=3.64; 95%CI 1.59-8.32. Uveitis and corneal opacities were also important findings, indicating the strong need for periodic ophthalmological follow-up in all HTLV-1 subjects.Com o objetivo de determinar a prevalência de lesões oculares, em portadores de HTLV-1 em Salvador, Bahia, foi realizado um estudo transversal em 140 pacientes (90 assintomático e 50 com paraparesia espática tropical/mielopatia associada ao vírus linfotrópico de células T humanas entre junho de 2004 e novembro de 2005. O exame oftalmológico incluiu medida da acuidade visual, exame da motilidade ocular, biomicroscopia anterior e posterior, pressão intraocular e avaliação do filme lacrimal. Observamos 4.0 (2.8% pacientes com uveites (dois com uveíte intermediária e dois com panuveíte e 39 (36,4% pacientes com ceratoconjuntivite seca. A prevalência de Ceratoconjuntivite seca foi significantemente mais elevada entre os pacientes com TSP/HAM (RC ajustada para idade = 3,64; IC 95% 1,59-8,32. As uveítes e opacidades corneanas foram também, patologias importantes, indicando a necessidade de acompanhamento oftalmológico periódico nos portadores de HTLV-1.

  10. Levantamento de cauxi (Porifera, Demospongiae, provável agente etiológico de doença ocular em humanos, Araguatins, rio Araguaia, Estado do Tocantins, Brasil Survey for cauxi (Porifera, Demospongiae, urged by the outbreak of human ocular injuries at Araguatins, Araguaia river, Tocantins State, Brazil

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    Cecilia Volkmer-Ribeiro

    2007-03-01

    Full Text Available Um surto recente de lesões oculares em humanos, ocorrido na localidade de Araguatins, à margem direita do rio Araguaia, Estado do Tocantins, caracterizou-se por irritação ocular seguida de prurido e produção de lesões conjuntivais, em crianças e adultos, particularmente do sexo masculino, após banho e mergulho com olhos abertos nas águas do rio, durante a estação seca de 2005. Registros publicados de dermatites pruriginosas causados pela presença de espículas de esponjas (cauxi em rios da Amazônia Central, induziram as autoras a realizarem levantamento urgente para busca de esponjas e suas espículas na água e sedimentos do rio no local, em diversas estações de amostragem georreferenciadas. Dez espécies de esponjas foram detectadas após o achado de gêmulas e espículas retidas nos sedimentos e em suspensão nas águas. É fornecida a lista das espécies e ilustrações das respectivas espículas para fins de sua detecção particularmente nos tecidos oculares alterados, cirurgicamente extraídos, fornecendo-se assim subsídios para comprovação da etiologia do surto e para procedimentos preventivos a serem tomadas pelas autoridades em saúde junto à população local.The recent outbreak of human ocular injuries, most in the conjunctive, occurred in the town of Araguatins, at the right bank of Araguaia river, State of Tocantins, Brazil, along the low water period of 2005, affected particularly male children and adults and had as main characteristic eye irritation and itching after bathing and diving with open eyes in the river waters, followed by appearance of ocular injuries. The large number of registers of itching and ulceration caused by sponge (cauxi spicules in rivers of Central Amazonia urged the authors to undertake a survey for sponges and its spicules in the river waters and sediments in several GPS referred stations at the site. Ten sponge species were detected upon the finding of gemmules as well as upon

  11. Lente intra-ocular opaca em diplopia intratável: relato de caso Opaque intraocular lens in intractable diplopia: case report

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    Fernanda Teixeira Krieger

    2006-08-01

    Full Text Available Diplopia intratável tem sido descrita em várias situações. Métodos convencionais como prismas e correção cirúrgica do estrabismo falham em neutralizá-la. O objetivo do trabalho é documentar o caso de uma paciente com estrabismo de longa data, cuja diplopia deteriorou-se ao longo dos anos, e não foi possível resolução com cirurgia, prisma, e oclusão com óculos e lente de contato com pupila opaca. A paciente foi então submetida à facoemulsificação com implante de lente intra-ocular opaca que atingiu o objetivo desejado.Intractable diplopia has been described in many situations but poor results are the rule with standard treatment modalities. The authors report a case of a woman with long-standing strabismus and diplopia who failed to improve following surgery, prism, and occlusive spectacles or contact lenses. Then, she was submitted to phacoemulsification and opaque intraocular lens implantation, which successfully neutralized diplopia.

  12. Ocular Sarcoidosis

    Science.gov (United States)

    Pasadhika, Sirichai; Rosenbaum, James T

    2015-01-01

    Sarcoidosis is one of the leading causes of inflammatory eye disease. Ocular sarcoidosis can involve any part of the eye and its adnexal tissues, and may cause uveitis, episcleritis/scleritis, eyelid abnormalities, conjunctival granuloma, optic neuropathy, lacrimal gland enlargement and orbital inflammation. Glaucoma and cataract can be complications from inflammation itself or adverse effects from therapy. Ophthalmic manifestations can be isolated, or associated with other organ involvement. Patients with ocular sarcoidosis can present with a wide range of clinical presentations and severity. Multi-disciplinary approaches are required to achieve the best treatment outcomes for both ocular and systemic manifestations. PMID:26593141

  13. Traumatismos oculares Ocular traumas

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    Gelen Welch Ruiz

    2007-12-01

    Full Text Available Se realizó un estudio descriptivo de tipo retrospectivo longitudinal cuyo universo estuvo constituido por 72 ojos de 72 pacientes con traumatismos oculares mecánicos que fueron hospitalizados en el Hospital Militar Central “Dr. Carlos J. Finlay” desde enero de 1999 hasta enero de 2005. Para el análisis estadístico de la información se utilizó el programa automatizado SPSS versión 11.5 en el cual también se conformó la base de datos y se realizaron los cálculos de acuerdo con el tipo de variable analizada. Se utilizaron medidas de resumen, tendencia central y asociación estadística con un nivel de significación de p A retrospective longitudinal and descriptive study was carried out in 72 eyes from 72 patients with mechanical occular traumas, who had been hospitalized in “Dr. Carlos J. Finlay” Military Hospital from December 1999 to January 2005. For the statistical data analysis, an automated program (SPSS 11.5 version was used to create the database and estimations were made according to the variable types. Summary measures, central tendency measures and statistical association with significance level equal to p < 0.05 were employed. Males prevailed (95.8%, the average age was 30.26 years with a minimum rate of 17 years and maximum rate of 82 years. The most frequent mechanisms of trauma were aggressions (23. 6% and injures from secondary projectiles (13.9%. The anterior segment traumas were more frequent (61, 1% than posterior segment traumas (6.94%. Both segments of the eyeball were affected in 39, 1% of eyes which evinced the worst visual acuity. The most common associated injures were hyphema (54, 2% and vitreous hemorrhage (16.6%. Closed trauma (contusions were more common and most of the eyes had better final visual acuity (45, 2% with vision range of 0.6-1.0 and 26.2% with vision range of 0.59-0.1. On the other hand, eyes affected by open trauma (simple wound, contusion-wound, wound with intraocular foreign body and

  14. Ocular Injury

    Science.gov (United States)

    ... Conditions Frequently Asked Questions Español Condiciones Chinese Conditions Ocular Injury En Español What causes eye injuries ? Injuries ... only the eyelid but the structures that drain tears from the eye. Lacerations of the eyelid or ...

  15. Ocular Rosacea

    Science.gov (United States)

    ... default.asp. Accessed March 31, 2015. Bron A. Ocular rosacea. http://www.uptodate.com. Accessed March 31, 2015. Riordan-Eva P, et al. Conjunctiva and tears. In: Vaughan & Asbury's General Ophthalmology. 18th ed. New ...

  16. Ocular rosacea

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    Đaković Zorana

    2004-01-01

    Full Text Available Five cases of ocular rosacea (one male and four females are reported in this paper. Two of the patients were with keratoconjunctivitis sicca, one with conjunctivitis chronica and blepharitis, one with conjunctivitis chronica and meibomitis, and one with reccurent corneal erosions with meibomitis and chordeloum. In four patients ocular symptoms preceded the occurence of skin lesions. The treatment with oral tetracyclines significantly improved the state of ocular rosacea in four patients, while in one case the changes of the anterior eye segment progressed in more severe state of ulcerative keratitis. It is considered that in almost 20% of the patients with rosacea ocular lesions may precede the skin changes, representing a diagnostic problem. Thus, in those cases multidisciplinary approach is suggested. Such approach is particularly important because of the decrease of morbidity and the prevention of the onset of the eye complications such as drastic worsening of visual acuity, i.e., the blindness.

  17. Avaliação da função lacrimal, da superfície ocular e do filme lacrimal em pacientes soropositivos para o HIV

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    Carolina Ramos Mosena

    2015-06-01

    Full Text Available Objetivo Avaliar a função lacrimal, a superfície ocular e o filme lacrimal de pacientes com sorologia positiva para o vírus HIV. Métodos Estudo observacional, transversal, quantitativo e analítico, realizado entre junho e outubro de 2011, no Departamento de Oftalmologia do Hospital do Servidor Público Estadual “Francisco Morato de Oliveira”, com 32 pacientes no total, sendo 16 soropositivos para o HIV e 16 soronegativos. Resultados Não houve diferença estatística significante na média de idade entre os grupos estudados (p = 0,083. O padrão do teste de cristalização da lágrima foi estatisticamente diferente no grupo de pacientes HIV (com predomínio dos padrões III e IV em relação ao grupo controle (no qual predominaram os padrões I e II, tanto no olho direito como no esquerdo (p = 0,019 e p < 0,001, respectivamente. As demais variáveis estudadas não mostraram-se estatisticamente relevantes entre os grupos. Conclusão Os pacientes soropositivos para o HIV não apresentaram alterações da função lacrimal e da superfície ocular, porém amostras de lágrimas evidenciaram diferenças consideradas estatisticamente significantes nos padrões dos testes de cristalização do filme lacrimal, quando comparadas com amostras obtidas de pacientes controles.

  18. Avaliação da função lacrimal, da superfície ocular e do filme lacrimal em pacientes soropositivos para o HIV

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    Carolina Ramos Mosena

    2015-04-01

    Full Text Available Objetivo: Avaliar a função lacrimal, a superfície ocular e o filme lacrimal de pacientes com sorologia positiva para o vírus HIV. Métodos: Estudo observacional, transversal, quantitativo e analítico, realizado entre junho e outubro de 2011, no Departamento de Oftalmologia do HSPE-SP, com 32 pacientes no total, sendo 16 soropositivos para o HIV e 16 soronegativos. Resultados: Não houve diferença estatística significante na média da idade entre os grupos estudados (p = 0,083. O padrão do teste de cristalização da lágrima foi estatisticamente diferente no grupo de pacientes HIV (com predomínio dos padrões III e IV em relação ao grupo controle (no qual predominaram os padrões I e II, tanto no olho direito como no esquerdo (p = 0,019 e p < 0,001, respectivamente. As demais variáveis estudadas não mostraram-se estatisticamente relevantes entre os grupos. Conclusão: Os pacientes soropositivos para o HIV não apresentaram alterações da função lacrimal e da superfície ocular, porém amostras de lágrimas evidenciaram diferenças consideradas estatisticamente significantes nos padrões dos testes de cristalização do filme lacrimal, quando comparadas com amostras obtidas de pacientes controles.

  19. Meloxicam e prednisona: efeitos do tratamento oral de curto prazo sobre os níveis de pressão intra-ocular em cães

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    Maria Alice Fusco

    2009-10-01

    Full Text Available Para possível observação da hipertensão ocular com o uso de anti-inflamatórios, foram selecionados 28 cães da raça Beagle. Para avaliação da pressão intra-ocular antes do tratamento, no dia 0 (zero todos os animais tiveram a pressão intra-ocular avaliada às 08 horas e às 16 horas. No dia seguinte dez cães receberam meloxicam na dose de 0,2 mg/kg, e 0,1mg/kg nos restantes quatro dias. Nove cães receberam prednisona na dose de 1,0 mg/kg durante cinco dias. Nove cães receberam somente porção de ração úmida. No quinto dia do tratamento todos os animais tiveram novamente a pressão intra-ocular avaliada às 08 horas e às 16 horas. Em todos os grupos, incluindo o grupo-controle, as maiores médias de pressão intra-ocular foram observadas no dia 5 (cinco. A diferença dos valores de pressão intra-ocular observada entre as medições das 08 horas e das 16 horas foi significativa, independente do tratamento e do dia considerado. O uso dos anti-inflamatórios esteroidal e não-esteroidal não foi capaz de causar hipertensão ocular e alguns fatores podem ser incriminados, como via de administração, dose e duração do tratamento utilizado, além da ausência de doença glaucomatosa nos cães selecionados.

  20. INTRAOCULAR TRANSMISSIBLE VENEREAL TUMOR IN A DOG TUMOR VENÉREO TRANSMISSÍVEL INTRA-OCULAR EM CÃO

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    Geórgia Nadalini Rodrigues

    2001-02-01

    , caracterizados por células redondas com núcleo grande e nucléolo proeminente localizado centralmente. O citoplasma apresentou-se pálido e com presença de vacúolos pequenos e arredondados. O diagnóstico de TVT com acometimento intra-ocular e metástases em linfonodos foi baseado nos achados clínicos, citológicos e histopatológicos.

  1. Frequência de lesões sugestivas de toxoplasmose ocular em uma população rural do Estado do Rio de Janeiro Frequency of lesions suggestive of ocular toxoplasmosis among a rural population in the State of Rio de Janeiro

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    Ana Luisa Quintella do Couto Aleixo

    2009-04-01

    Full Text Available Para determinar a prevalência da toxoplasmose ocular na população em geral do bairro de Santa Rita de Cássia, Barra Mansa, RJ, foi realizado um estudo seccional no qual 1.071 indivíduos foram submetidos a testes sorológicos (IgG e IgM anti-Toxoplasma e a exame físico e oftalmológico. O diagnóstico da toxoplasmose ocular presumida foi baseado em critérios clínicos, sorológicos e aspecto da lesão retinocoroidiana. As lesões foram classificadas em três tipos morfológicos: 1. Limites marcados com halo de hiperpigmentação e área de atrofia coriorretiniana central. 2. Halo hipopigmentado e área central hiperpigmentada e 3. Hiperpigmentadas ou hipopigmentadas. A prevalência de lesões cicatrizadas compatíveis com toxoplasmose ocular foi de 3,8% na população em geral e 5,8% entre os indivíduos com sorologia positiva para Toxoplasma gondii (65,9% dos indivíduos analisados, com predominância de: lesões do tipo 1 (41,5%, sexo feminino (68,3%, periféricas (58,5% e menores que 3 diâmetros de disco (87,8%.To determine the prevalence of ocular toxoplasmosis among the general population of the district of Santa Rita de Cassia, Barra Mansa, State of Rio de Janeiro, a cross-sectional study on 1,071 individuals was performed. These subjects underwent serological tests (anti-Toxoplasma IgG and IgM and physical and ophthalmological examinations. The diagnosis of presumed ocular toxoplasmosis was based on clinical and serological criteria and the appearance of the retinochoroidal lesion. The lesions were classified into three morphological types: 1. Limits marked with a halo of hyperpigmentation and an area of central chorioretinal atrophy; 2. Hypopigmented halo and hyperpigmented central area; and 3. Hyperpigmented or hypopigmented. The prevalence of healed lesions compatible with ocular toxoplasmosis was 3.8% among the general population and 5.8% among individuals who were seropositive for Toxoplasma gondii (65.9% of the individuals

  2. Efeito do uso de lente escleral cosmética na sensibilidade tátil corneal em phthisis bulbi Effect of ocular prosthesis on cornea sensitivity in phthisis bulbi

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    Lucia Miriam Dumont Lucci

    2004-10-01

    Full Text Available OBJETIVOS: Comparar a sensibilidade tátil corneal entre olhos normais e aqueles com phthisis bulbi e avaliar as alterações provocadas na sensibilidade tátil corneal pelo uso de lente escleral cosmética em phthisis bulbi. MÉTODOS: Estudo prospectivo de 23 pacientes com phthisis bulbi unilateral. Foram realizadas medidas da sensibilidade tátil corneal em ambos os olhos utilizando-se o estesiômetro de Cochet-Bonnet antes e após 3 meses do uso da lente escleral cosmética. RESULTADOS: Em todos os pacientes, a medida da sensibilidade tátil corneal no olho com phthisis bulbi foi menor do que no contralateral (controle. Em 96% houve diminuição da sensibilidade tátil corneal após a adaptação da lente escleral cosmética. CONCLUSÃO: Após a adaptação da lente escleral cosmética, ocorre diminuição da sensibilidade tátil corneal nos olhos. A fisiopatologia é semelhante à encontrada nos usuários de lentes de contato.PURPOSE: To compare corneal sensitivity between normal eyes and those whith phthisis bulbi and also to analyze the alterations of corneal sensitivity in phthisis bulbi induced by wearing ocular prosthesis. METHODS: Prospective study of 23 patients with unilateral phthisis bulbi. Bilateral cornea sensitivity was evaluated using the Cochet-Bonnet esthesiometer before and after 3 months of wearing ocular prosthesis. RESULTS: In all patients, corneal sensitivity of the eye with phthisis bulbi was lower than that of the normal eye (control. In 96% there was decrease of corneal sensitivity after adaptation of ocular prosthesis. CONCLUSION: After wearing ocular prosthesis, there is a reduction in corneal sensitivity in phthisis bulbi. The pathophysiology seems to be the same as that found in contact lens wearers.

  3. Ensino de oncologia na formação do enfermeiro Enseñanza de oncología en la formación del enfermero Teaching of oncology in nurse's education

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    Ana Maria Calil

    2010-08-01

    Full Text Available Trata-se de um artigo reflexivo acerca da necessidade de introdução da disciplina de oncologia nas Escolas de Graduação em Enfermagem em nosso meio. Tem como objetivos pensar a disciplina de oncologia no currículo de graduação em enfermagem, pontuando aspectos relevantes de sua inserção, considerando a capacitação e qualificação profissional, a necessidade do mercado de trabalho, o perfil epidemiológico brasileiro e uma formação reflexiva e crítica acerca das competências profissionais do enfermeiro. Pontua-se também o papel do desenvolvimento tecnológico contribuindo nessa formação e educação de novos profissionais de saúde.Tratamos de un artículo reflexivo sobre la necesidad de introducción de la disciplina de oncologia en las Escuelas de Graduación en Enfermería de nuestro medio. Tiene como objetivos pensar en la disciplina en el currículo de graduación en enfermería, puntuando aspectos importantes de su inserción. Para tanto, considera la capacitación y calificación profesional, la necesidad del mercado de trabajo, el perfil epidemiológico brasileño y una formación reflexiva y crítica sobre las competencias profesionales del enfermero. También es puntuado el papel del desarrollo tecnológico contribuyendo en esa formación y educación de nuevos profesionales de la salud.The aim of the present study was to think the Oncology Course in the baccalaureate nursing curriculum pointing relevant issues about its introduction, considering professional training and qualification, labor market demand and a critical reflection about nurse's professional competences. Score is also the role of technology in helping training and education of new health professionals.

  4. Sistematização da assistência de enfermagem em cuidados paliativos na oncologia: visão dos enfermeiros Sistematización de la asistencia de enfermería en cuidados paliativos en oncología: visión de los enfermeros Standardization of nursing care in a palliative care oncology setting: perceptions of nurses

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    Marcelle Miranda da Silva

    2011-01-01

    Full Text Available OBJETIVOS: Descrever a visão dos enfermeiros a respeito da sistematização da assistência de enfermagem (SAE a clientes com câncer avançado em cuidados paliativos; analisar os fatores intervenientes na implantação da SAE na visão dos enfermeiros e discutir possíveis estratégias propostas pelos enfermeiros que favoreçam sua implantação nesse cenário. MÉTODOS: Pesquisa qualitativa, descritiva. Participaram oito enfermeiras do Hospital do Câncer IV, unidade do Instituto Nacional do Câncer especializada na área, localizada no Município do Rio de Janeiro, Brasil. Foram usadas a técnica do grupo focal e a análise de conteúdo. RESULTADOS: Os discursos dos sujeitos indicaram que a unidade encontrava-se na fase de planejamento de implantação da SAE, bem como o reconhecimento dos desafios do processo relacionados com sua complexidade e o contexto de atuação. CONCLUSÕES: Como principal estratégia para implantação da SAE evidenciou-se a necessidade de capacitação da equipe em relação à fundamentação teórica e preparo para a tomada de decisão frente à complexidade da área.OBJETIVOS: Describir la visión de los enfermeros respecto a la sistematización de la asistencia de enfermería (SAE a clientes con cáncer avanzado en cuidados paliativos; analizar los factores intervinientes en la implantación de la SAE en la visión de los enfermeros y discutir posibles estrategias propuestas por los enfermeros que favorezcan su implantación en ese escenario. MÉTODOS: Se trata de una investigación cualitativa, descriptiva. Participaron ocho enfermeras del Hospital del Cáncer IV, unidad del Instituto Nacional del Cáncer especializada en el área, localizada en el Municipio de Rio de Janeiro, Brasil. Se usó la técnica del grupo focal y el análisis de contenido. RESULTADOS: Los discursos de los sujetos reflejan que la unidad se encontraba en la fase de planificación de la implantación de la SAE, así como el

  5. Nursing professionals' anxiety and feelings in terminal situations in oncology Ansiedades y sentimientos de los profesionales de enfermería en situaciones de terminalidad en oncología Ansiedades e sentimentos de profissionais da enfermagem nas situações de terminalidade em oncologia

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    Daniella Antunes Pousa Faria

    2007-12-01

    com o paciente terminal com câncer, procurando identificar os fatores que a influenciam, bem como os sentimentos dos profissionais frente ao atendimento destes pacientes. Foram analisados 50 auxiliares e técnicos de enfermagem do hospital de referência de atendimento ao câncer do Rio Grande do Norte. Os dados foram coletados através de questionário e do Inventário de Ansiedade Traço-Estado. Os resultados revelaram que 69,8% dos profissionais possuem Ansiedade-Estado média e 30,2% alta. O número de pacientes atendidos e 'trabalhar em outra instituição' interferiram na Ansiedade-Estado. Os sentimentos mais destacados foram sofrimento e tristeza, e 'criança' foi apontada como sendo a faixa-etária mais difícil de se lidar. Verifica-se a necessidade de realização de estratégias de apoio para profissionais a fim de reduzir e/ou prevenir altos níveis de ansiedade e estresse.

  6. Alterações oculares nos pacientes portadores de lúpus eritematoso sistêmico em acompanhamento ambulatorial Ophthalmological alterations in outpatients with systemic lupus erythematosus

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    Tatiana Klejnberg

    2006-04-01

    Full Text Available OBJETIVO: Avaliar as alterações oftalmológicas encontradas em pacientes portadores de lúpus eritematoso sistêmico (LES, em acompanhamento ambulatorial. MÉTODOS: Foi realizado estudo descritivo transversal incluindo 70 pacientes com diagnóstico de LES baseado nos critérios do Colégio Americano de Reumatologia. Os pacientes foram analisados em relação ao sexo, idade, etnia, tempo de duração e presença da atividade da doença, uso de corticoesteróides e antimaláricos, presença de sintomas oftalmológicos e exame oftalmológico completo. RESULTADOS: 62 pacientes (88,6% eram do sexo feminino, 43 pacientes (61,4% de etnia branca. A idade média encontrada foi 43,9 anos e 57 pacientes (81,4% apresentavam-se sem sinais de atividade da doença. Quarenta e seis pacientes (65,7% apresentavam queixa oftalmológica. A síndrome do olho seco foi diagnosticada em 22 pacientes (31,4%, ao passo que catarata subcapsular posterior bilateral ocorreu em 15 pacientes (21,1% e glaucoma em 2 pacientes (2,9%. No exame do fundo de olho, 8 pacientes (11,4% apresentavam drusas coroidianas, 7 (10% atrofia do epitélio pigmentário da retina macular, 2 (2,9% escavação do disco óptico patológica, 2 (2,9% tortuosidade vascular e cruzamentos patológicos, 1 (1,4% cicatriz de coriorretinite macular e 1 (1,4% seqüela de oclusão de ramo da veia central da retina. CONCLUSÃO: O LES é doença sistêmica que pode apresentar comprometimento oftalmológico, geralmente benigno em pacientes ambulatoriais. A síndrome do olho seco e a catarata foram as alterações oftalmológicas mais freqüentemente encontradas. Entretanto, a primeira parece estar mais relacionada ao LES em si, ao passo que a segunda possivelmente se relaciona ao uso crônico de corticoesteróides para o tratamento da doença. O uso de antimaláricos não é causa frequente de lesão oftalmológica, porém estudos mais específicos são necessários para avaliar o real impacto a longo prazo do

  7. Ocular Straylight

    Directory of Open Access Journals (Sweden)

    Sigrid Mueller-Schotte OD, MSc

    2015-10-01

    Full Text Available Intra-ocular straylight can cause decreased visual functioning, and it may cause diminished vision-related quality of life (VRQOL. This cross-sectional population-based study investigates the association between straylight and VRQOL in middle-aged and elderly individuals. Multivariable linear regression analyses were used to assess the association between straylight modeled continuously and cutoff at the recommended fitness-to-drive value, straylight ≥ 1.4 log(s, and VRQOL. The study showed that participants with normal straylight values, straylight ≤ 1.4 log(s, rated their VRQOL slightly better than those with high straylight values (straylight ≥ 1.4 log(s. Furthermore, multivariable regression analysis revealed a borderline statistical significant association ( p = .06 between intra-ocular straylight and self-reported VRQOL in middle-aged and elderly individuals. The association between straylight and self-reported VRQOL was not influenced by the status of the intra-ocular lens (natural vs. artificial intra-ocular lens after cataract extraction or the number of (instrumental activities of daily living that were reported as difficult for the elderly individuals.

  8. Ocular Straylight

    Science.gov (United States)

    Mueller-Schotte, Sigrid; van der Schouw, Yvonne T.; Schuurmans, Marieke J.

    2015-01-01

    Intra-ocular straylight can cause decreased visual functioning, and it may cause diminished vision-related quality of life (VRQOL). This cross-sectional population-based study investigates the association between straylight and VRQOL in middle-aged and elderly individuals. Multivariable linear regression analyses were used to assess the association between straylight modeled continuously and cutoff at the recommended fitness-to-drive value, straylight ≥ 1.4 log(s), and VRQOL. The study showed that participants with normal straylight values, straylight ≤ 1.4 log(s), rated their VRQOL slightly better than those with high straylight values (straylight ≥ 1.4 log(s)). Furthermore, multivariable regression analysis revealed a borderline statistical significant association (p = .06) between intra-ocular straylight and self-reported VRQOL in middle-aged and elderly individuals. The association between straylight and self-reported VRQOL was not influenced by the status of the intra-ocular lens (natural vs. artificial intra-ocular lens after cataract extraction) or the number of (instrumental) activities of daily living that were reported as difficult for the elderly individuals. PMID:28138473

  9. Ocular toxicology.

    Science.gov (United States)

    Novack, G D

    1997-12-01

    This review of recent articles on ocular toxicology concentrates on undesirable effects on the eye induced by systemically used xenobiotics. These include color vision deficiencies or visual field deterioration related to antiepileptic drugs, elevated intraocular pressure associated with inhaled corticosteroids, retinal detachments associated with systemic corticosteroids, rifabutin-induced uveitis, cocaine-related retinal hemorrhagic lesions in utero, deferoxamine-related decreases in vision, ocular allergy to bovine-derived collagen, and a large case study of hydroxychloroquine retinotoxicity. Other publications reviewed include a controlled study showing that glucose levels do not seem to alter color vision, a report that intravenous methotrexate can reach clinically meaningful levels in the aqueous humor, and a study showing the effect of systemic pentoxifylline on ocular blood flow and diabetes. With respect to systemic effects of topical ocular medications, there was a case report of apparent systemic exposure to pilocarpine from an Ocusert (Alza Corp., Palo Alto, CA), generalized urticaria after a single application of 1% cyclopentolate, and asthma induced with topical ketorolac. Readers are reminded that no drug achieves ultimate efficacy or ultimate safety. Thus, the decision to employ a given therapy involves a physician's evaluation of its therapeutic index, that is, the ratio between efficacy and toxicity.

  10. Autologous grafting of extraocular muscles: experimental study in rabbits Transplante autólogo de musculatura ocular extrínseca: estudo experimental em coelhos

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    Jorge Meireles-Teixeira

    2005-06-01

    Full Text Available PURPOSE: To evaluate the feasibility of autologous extraocular muscle grafting as a type of muscle expansion surgery. METHODS: The left superior rectus muscle of twenty-nine rabbits was resected and this fragment was attached to the endpoint of the respective right superior rectus (test group. Thereafter, the superior rectus of the left eye was reattached to the sclera (control group. Both groups were examined during different postoperative periods in order to assess their outcomes. RESULTS: The presence of hyperemia was slightly more frequent in the grafted group. Secretion and muscle atrophy were negligible in both groups. Fibrosis was greater in grafted animals. These muscles were weaker than the control muscles, although the force required to split muscular parts was always greater than the physiological one. CONCLUSIONS: This surgical technique was reliable and useful if one intends to achieve muscle expansion without the intrinsic risks of dealing with heterologous/artificial materials.OBJETIVO: Avaliar a viabilidade do uso de segmentos de músculos oculares extrínsecos como expansores de tendões musculares. MÉTODOS: Vinte e nove coelhos tiveram seu músculo reto superior esquerdo ressecado e o fragmento de cada um foi transplantado para o reto superior contralateral (grupo-teste. Então, o reto superior esquerdo foi reinserido na esclera (grupo-controle. Os animais foram então examinados em diversos períodos pós-operatórios, até os seus sacrifícios, para que se avaliasse o desenrolar dessa técnica cirúrgica. RESULTADOS: A hiperemia foi maior entre os testes. A secreção e a atrofia muscular foram mínimas nos dois grupos. Houve maior presença de fibrose no grupo-teste, mas não tão expressiva a ponto de inviabilizar os efeitos da cirurgia. Esses músculos também se romperam mais facilmente do que os do grupo-controle, porém, a força de rompimento foi sempre bem maior do que aquela presente numa contração muscular normal

  11. Freqüência das alterações oftalmológicas em pacientes com hanseníase residentes em hospital-colônia Frequency of ocular changes in patients with Hansen's disease living in a colony hospital

    Directory of Open Access Journals (Sweden)

    Francineide Sadala de Souza

    2005-06-01

    Full Text Available OBJETIVOS: Identificar a freqüência das alterações oculares em pacientes hansenianos residentes em hospital-colônia; comprovar a predileção pelo segmento anterior do olho em relação ao posterior. MÉTODOS: Fez-se estudo transversal de 115 olhos de 58 pacientes internados no abrigo João Paulo II, em Marituba - Pará, no período de agosto a outubro de 1999. Os dados epidemiológicos da pesquisa foram obtidos da ficha de cada paciente e de dados colhidos durante o exame oftalmológico. Todos os pacientes estudados estavam curados da hanseníase segundo as normas do Ministério da Saúde. RESULTADOS: Em 114 olhos (99,1% foi observado envolvimento ocular, sendo a maioria (77,2% pertencente à forma virchowiana. Os achados oculares mais freqüentes nos anexos oculares foram a madarose ciliar parcial (70,4% e a madarose superciliar parcial (59,1%. Quanto ao bulbo ocular, o achado mais freqüente relacionado à hanseníase foi a diminuição e/ou ausência de sensibilidade corneana observada em 42,6% dos olhos, seguida da midríase paralítica (16,5% encontrada no pós-operatório dos pacientes submetidos a facectomia, achado ligado intimamente à atrofia de íris (8,7%, comumente observada nestes pacientes. Não foi encontrada nenhuma alteração à fundoscopia que pudesse ser atribuída à hanseníase. CONCLUSÕES: A alta prevalência de alterações do bulbo ocular e anexos em pacientes portadores de hanseníase, principalmente na forma virchowiana, indicam a necessidade da assistência contínua a esses pacientes mesmo após a cura da doença.PURPOSE: To identify the frequency of ocular changes in patients with Hansen's disease, living in a colony hospital; to confirm the predilection for the anterior segment of the eye instead of the posterior segment. METHODS: Transversal study of 115 eyes of 58 in-patients at João Paulo II colony, Marituba - Pará, from August to October 1999. The epidemiologic data of this research were obtained from

  12. [Ocular burns].

    Science.gov (United States)

    Merle, H; Gérard, M; Schrage, N

    2008-09-01

    Ocular or thermal burns account for 7.7%-18% of ocular trauma. The majority of victims are young. The burns occur in the setting of accidents at work or in the home, or during a physical attack. Chemical burns by strong acids or bases are responsible for the most serious injuries. Associated with the destruction of limbal stem cells, they present as recurrent epithelial ulcerations, chronic stromal ulcers, deep stromal revascularization, conjunctival overlap, or even corneal perforation. The initial clinical exam is sometimes difficult to perform in the presence of burning symptoms. Nevertheless, it enables the physician to classify the injury, establish a prognosis, and most importantly, guide the therapeutic management. The Roper-Hall modification of the Hughes classification system is the most widely utilized, broken down into stages based on the size of the stromal opacity and the extent of possible limbal ischemia. This classification is now favorably supplemented by those proposed by Dua and Wagoner, which are based on the extent of the limbal stem cell deficiency. The prognosis of the more serious forms of ocular burns has markedly improved over the last decade because of a better understanding of the physiology of the corneal epithelium. Surgical techniques aimed at restoring the destroyed limbal stem cells have altered the prognosis of severe corneal burns. In order to decrease the incidence of burns, prevention, particularly in industry, is essential.

  13. Detecção de alterações na camada de fibras nervosas da retina por meio do laser confocal polarizado em hipertensão ocular antes do surgimento de defeitos perimétricos Detection of retinal nerve fiber layer changes in ocular hypertension with scanning laser polarimetry before the appearance of perimetric defects

    Directory of Open Access Journals (Sweden)

    Roberto Lauande-Pimentel

    2004-10-01

    Full Text Available OBJETIVO: Avaliar a capacidade do laser confocal polarizado (LCP em detectar alterações na camada de fibras nervosas (CFN de hipertensos oculares antes do aparecimento de alteração campimétrica. Desenho- Retrospectivo, caso-controle. MÉTODOS: Pacientes hipertensos oculares divididos em dois grupos: a estáveis e b conversores (que progrediram com dano perimétrico glaucomatoso. Parâmetros de retardo obtidos por meio do programa NFA/GDx. RESULTADOS: Um total de 108 pacientes estáveis e 13 conversores foram estudados por período médio de seguimento acima de 35 meses nos dois grupos. Diversos parâmetros do LCP mostraram diferenças significativas na espessura da CFN entre os dois grupos no inicio do seguimento (média de 27,4 meses antes do aparecimento de lesão perimétrica. Os parâmetros The Number, Maximum Modulation e Superior Average permaneceram diferentes entre os grupos no início e no final do seguimento. O odds ratio para desenvolvimento de conversão perimétrica, dado um resultado de The Number alterado (>32, foi estimado em 7,9 para esta série. CONCLUSÕES: O LCP foi capaz de detectar alterações significativas na CFN no grupo de hipertensos oculares que desenvolveram posteriormente lesão perimétrica glaucomatosa. Neste estudo, o resultado inicial anormal de The Number foi o principal fator de risco para desenvolvimento de alteração perimétrica futura em pacientes hipertensos oculares.OBJECTIVE: To evaluate the ability of the Confocal Scanning Laser Polarimeter (SLP to detect glaucoma alterations before the appearance of perimetric defects. Design- retrospective, case-control. METHODS: Ocular hipertensive patients divided in to two groups: a stable and b conversors (that have conversed to perimetric defined glaucoma. Nerve Fiber Analyser/GDx parameters of retardation. RESULTS: A total of 108 stable and 13 conversors were evaluated for a mean period over 35 months in each group. At the initial examination, several

  14. Preservação da fertilidade em pacientes com câncer Fertility preservation for oncologic patiens

    OpenAIRE

    Castellotti,Daniella S.; Cambiaghi,Arnaldo S.

    2008-01-01

    Os avanços tecnológicos dos últimos anos na área de oncologia têm proporcionado aos pacientes tratamentos que revolucionaram a esperança de ter uma vida melhor. Jovens que tinham, muitas vezes, um futuro sombrio podem agora olhar com esperanças concretas a cura de sua doença. Entretanto, esta evolução nem sempre tem evitado o prejuízo da saúde reprodutiva causado pelas cirurgias, quimioterapias ou radioterapias, comuns a estes pacientes. Os especialistas em Hematologia e Oncologia devem ter c...

  15. DESVELANDO O CUIDADO HUMANIZADO: PERCEPÇÕES DE ENFERMEIROS EM ONCOLOGIA PEDIÁTRICA

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    Maiara Rodrigues dos Santos

    2013-01-01

    Full Text Available Este estudio tuvo como objetivos revelar los elementos de la atención humanizada en el encuentro entre enfermero, familia y niño con cáncer, identificar las percepciones de los enfermeros sobre la atención humanizada y comprobar en que situaciones los enfermeros perciben que la humanización se relaciona con el cuidado. Este es un estudio exploratorio-descriptivo, con enfoque cualitativo. Se utilizó como marco teórico la teoría del cuidado humano de Watson. Los datos fueron recolectados a través de entrevistas semi-estructuradas con nueve enfermeras en un hospital público especializado en oncología pediátrica en São Paulo. Los resultados indicaran el fenómeno “Revelando el cuidado humanizado ofrecido a la familia y al niño con cáncer.” Los elementos teóricos surgieron a partir de descripciones de eventos clínicos o situaciones presentadas por los enfermeros. Los datos permitieron reflexiones acerca las posibilidades de construir un proceso interpersonal humanista en la oncología pediátrica y los avances y limitaciones en la aplicabilidad de este referencial en la práctica.

  16. EMPREGO DO RELAXAMENTO PARA ALÍVIO DA DOR EM ONCOLOGIA

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    MICHELE SALVADOR

    2008-01-01

    Full Text Available La finalidad de este estudio fue describir el uso de técnicas de relajación y sus beneficios para reducción del dolor oncológico. Se trata de una revisión de literatura, de 1993 a 2007, usando las palabras claves: dolor, relajación, cáncer y enfermería, en las bases Medline, Cinahl y Lilacs. De los 79 artículos identificados, 24 de ellos atendieron los propósitos. De estos, sólo uno era nacional; predominantemente de autores enfermeros, publicados en revistas norteamericanas de enfermería y distribuidos hasta el año 2000; dos de ellos eran relatos de experiencia, uno de directrices, un estudio de caso, 10 revisiones de literatura y 10 ensayos. Los autores emplearon las técnicas de relajación muscular progresiva, imagen guiada, biofeedback, hipnosis y meditación. Tales técnicas reducen la percepción del dolor oncológico, favorecen la disminución de narcóticos, náuseas, estrés, insomnio y actúan como auxiliar con los medicamentos; la enfermera ocupa papel relevante en su uso para aliviar el dolor.

  17. EMPREGO DO RELAXAMENTO PARA ALÍVIO DA DOR EM ONCOLOGIA

    OpenAIRE

    MICHELE SALVADOR; CÍNTIA CAPUCHO RODRIGUES; EMÍLIA CAMPOS DE CARVALHO

    2008-01-01

    La finalidad de este estudio fue describir el uso de técnicas de relajación y sus beneficios para reducción del dolor oncológico. Se trata de una revisión de literatura, de 1993 a 2007, usando las palabras claves: dolor, relajación, cáncer y enfermería, en las bases Medline, Cinahl y Lilacs. De los 79 artículos identificados, 24 de ellos atendieron los propósitos. De estos, sólo uno era nacional; predominantemente de autores enfermeros, publicados en revistas norteamericanas de enfermería y d...

  18. Enfermeiro Clinico Especialista: um modelo de pratica avancada de enfermagem em oncologia pediatrica no Brasil

    OpenAIRE

    Carla goncalves Dias; Adriana Maria Duarte; Adriane da Silva Santos Ibanez; Daniela Bonfietti Rodrigues; Daniele Porto Barros; Juliana dos Santos Soares; Juliana Pepe Marinho Perin; Nancy da Silva Santos; Priscila Mendes Paiva; Maria Gaby Rivero Gutierrez

    2013-01-01

    The objective of this paper is to report the experience of implementing a model of advanced nursing practice that integrates a clinical nurse specialist into the nursing staff. The authors describe the concept of this model and the process of its implementation in a pediatric oncology reference institution in the city of São Paulo, Brazil. The main result achieved in evaluating the clinical nurse specialist was strengthening of the role of the nurse as a reference professional for the articul...

  19. TWO-DIMENSIONAL REAL-TIME ULTRASONIC BIOMETRY OF OCULAR GLOBE OF DOMESTIC CATS. BIOMETRÍA ULTRASÓNICA BIDIMENSIONAL EN TIEMPO REAL DEL BULBO OCULAR DE GATOS. BIOMETRIA ULTRA-SONOGRÁFICA BIDIMENSIONAL EM TEMPO REAL DE BULBO OCULAR DE GATOS DOMÉSTICOS.

    Directory of Open Access Journals (Sweden)

    Ney Luis Pippi

    2009-09-01

    lente (D2, el diámetro de la lente (D3, la distancia entre la cápsula posterior de la lente hasta la retina (D4, y la distancia entre la córnea y la retina (D5. Las medidas habían sido agrupadas y conseguido medio, de los promedios fueron aplicados una prueba estadística del análisis de variación, con el nivel de la significación de el 5%, verificar la homogeneidad de las medidas. El extremo de los bulbos oculares saludables de gatos domésticos produce imágenes con las medidas medias de los 0,39cm para D1, los 0,68cm para D2, el 1,25cm para D3, los 0,78cm para D4 y el 1,86cm para D5. No se observo diferencia significativa entre el sexo, las edades aplicadas, los pesos o los cortes. O olho é um órgão ideal para o exame ultrassonográfico, porque é de fácil acesso e contém várias superfícies reflexivas ou interfaces. Para o exame ultrassonográfico do bulbo ocular são necessárias altas frequências para se delinear adequadamente os tecidos. Para a obtenção das medidas, foram utilizados sessenta olhos de trinta gatos, realizando-se cortes sagitais e transversais com transdutor microconvexo de 7,5MHz. Efetuaram-se medidas a partir da córnea em direção à retina. Foram registradas medidas da distância entre a córnea e a cápsula anterior da lente (D1, espessura da lente (D2, diâmetro da lente (D3, distância entre a cápsula posterior da lente até a retina (D4, e distância entre a córnea e a retina (D5. Agruparam-se as medidas e obtiveram-se as médias. A partir das médias, foi aplicado um teste estatístico de análise de variância, com nível de significância de 5%, para se verificar a homogeneidade das medidas. A ultrassonografia de bulbos oculares saudáveis de gatos domésticos produz imagens com medidas médias de 0,39cm para D1, 0,68cm para D2, 1,25cm para D3, 0,78cm para D4 e 1,86cm para D5. Não se observou diferença significativa entre os sexos, idades, pesos ou cortes aplicados.

    PALAVRAS-CHAVES: Biometria, gatos

  20. Perfil de pacientes acometidos por câncer de laringe atendidos no centro de oncologia bucal - UNESP = Patients’ profile attack for laryngeal cancer attended in oral cancer center - UNESP

    Directory of Open Access Journals (Sweden)

    Goiato, Marcelo Coelho

    2006-01-01

    Full Text Available Um estudo foi realizado no Centro de Oncologia Bucal da Universidade Estadual Paulista, Campus de Araçatuba. Entre 88 casos de câncer atendidos no Centro de tratamento oncológico entre 1991 e 2003, 80 casos de câncer de laringe foram identificados em homens. Sexo, idade, uso de tabaco e álcool, realização de cirurgia e tratamentos oferecidos após a cirurgia foram dados obtidos de pacientes com um questionário padrão. O maior número de casos de câncer de laringe ocorreu em região glótica e necessitou de intervenção cirúrgica (laringectomia parcial ou total. A freqüência de câncer de laringe foi mais alta em fumantes e foi mais comum em idade entre 50 e 69 anos. O tratamento fonoaudiológico e a utilização de prótese estética ainda estão restritos a menor porcentagem dos pacientes

  1. Transplante de membrana amniótica em casos agudos graves de queimadura ocular química e síndrome de Stevens-Johnson Amniotic membrane transplantation for severe acute cases of chemical ocular burn and Stevens-Johnson syndrome

    Directory of Open Access Journals (Sweden)

    José Reinaldo da Silva Ricardo

    2009-04-01

    Full Text Available OBJETIVO: Investigar o potencial terapêutico do transplante de membrana amniótica nos casos agudos graves de queimadura ocular química e síndrome de Stevens-Johnson. MÉTODOS: Foram analisados retrospectivamente os prontuários de oito pacientes, com um total de dez olhos, submetidos a transplante de membrana amniótica para tratamento de queimadura ocular química e síndrome de Stevens-Johnson na fase aguda entre janeiro de 1999 e maio de 2008 no Departamento de Oftalmologia da UNIFESP. Dados referentes a sexo, idade, grau da queimadura, etiologia, olho acometido, achados oftalmológicos, extensão da membrana amniótica, operações adicionais, tempo em dias entre a lesão e a cirurgia, acuidade visual antes e depois da cirurgia, defeito epitelial em dias, complicações e tempo de seguimento em meses foram coletados. RESULTADOS: A idade média dos pacientes foi de 35,7 ± 23,04 anos, dos quais seis eram homens e dois eram mulheres. Três pacientes (quatro olhos apresentaram síndrome de Stevens-Johnson e cinco pacientes (seis olhos apresentaram queimadura ocular química. O defeito epitelial foi cicatrizado em média de 27,8 ± 4,7 dias (variando de 20 a 35 dias. Todos os pacientes evoluíram com deficiência límbica em seguimento médio de 7,8 ± 2,8 meses (variando entre cinco e doze meses e quatro olhos desenvolveram simbléfaro. CONCLUSÕES: Os resultados sugerem que o transplante de membrana amniótica representa um aditivo que pode ser realizado nos casos agudos graves de queimadura ocular química e síndrome de Stevens-Johnson com a finalidade de promover a epitelização e suprimir a inflamação e suas consequências, se comparado a outros trabalhos que trataram casos semelhantes com terapia medicamentosa somente. Por outro lado, não é capaz de evitar a deficiência límbica nesses casos, que futuramente necessitarão de transplante de células-tronco do limbo ou outras cirurgias para correção da superfície ocular

  2. Cisticercosis ocular

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    Danaides Arencibia González

    Full Text Available La cisticercosis establece un grupo de enfermedades zoonóticas parasitarias; cuando se aloja en el ojo y sus anexos producen una cisticercosis ocular y periocular. Constituye una de las causas de uveítis ocular y pérdida importante de la visión. El diagnóstico clínico se realiza mediante la observación directa del parásito, cuando existen opacidades de los medios, el ultrasonido se emplea como medio diagnóstico útil. Los anti helmintos asociados a esteroides forman parte de su terapéutica, sumado al tratamiento definitivo de la extracción del parásito, en este tipo de afección mediante vitrectomía vía pars plana. Se presenta un caso portador de esta condición, se describen las características más importantes del cuadro clínico, diagnóstico, manejo y curso evolutivo-terapéutico.

  3. Aderência in vitro do Staphylococcus epidermidis e da Pseudomonas alcaligenes em lentes intra-oculares In vitro adherence of Staphylococcus epidermidis and Pseudomonas alcaligenes to intraocular lenses

    Directory of Open Access Journals (Sweden)

    Patrícia Ioschpe Gus

    2006-06-01

    Full Text Available OBJETIVO: Quantificar e comparar a aderência in vitro das bactérias Staphylococcus epidermidis e Pseudomonas alcaligenes em diferentes tipos de lentes intra-oculares (LIOs. MÉTODOS: Quatorze lentes intra-oculares foram usadas no experimento. Quatro de polimetilmetacrilato (PMMA, quatro de silicone, quatro de hidrogel e duas de acrílico. Oito lentes intra-oculares foram colocadas em oito tubos de ensaio contendo 4 ml de suspensão de Pseudomonas alcaligenes, e seis lentes intra-oculares foram colocadas em seis tubos de ensaio contendo 4 ml de suspensão de Staphylococcus epidermidis. A concentração do caldo utilizada para o teste de aderência foi de 10(8 unidades formadoras de colônias por mililitro (CFU/mL que corresponde a 0,5 na escala de McFarland. As lentes foram incubadas a 37° por duas horas. Após, foram removidas dos caldos e enxaguadas em água destilada estéril por duas vezes. As lentes foram cultivadas em placas de ágar-sangue a 35-37° e evaliadas a cada 24h por um período de 72h. Nas amostras que tiveram crescimento bacteriano, foram contadas as colônias utilizando os métodos convencionais de laboratório. Todos os ensaios foram executados em duplicata. RESULTADOS: A aderência do Staphylococcus epidermidis nas lentes de PMMA foi menor se comparada com as de silicone e de hidrogel. A aderência daPseudomonas alcaligenes nas lentes de hidrogel foi menor se comparada com as de silicone, PMMA e acrílico. CONCLUSÃO: Os resultados sugerem que a aderência do Staphylococcus epidermidis e da Pseudomonas alcaligenes nas lentes intra-oculares é influenciada pelo tipo de material da lente e pela espécie do microorganismo. A aderência bacteriana pode ter papel importante na patogenicidade da endoftalmite pós-cirurgia de catarata.PURPOSE: To quantify and compare the in vitro adherence of Staphylococcus epidermidis and Pseudomonas alcaligenes to different intraocular lenses (IOLs. METHODS: Fourteen intraocular lenses were

  4. Biomicroscopia ultra-sônica na avaliação da posição das lentes intra-oculares em uma técnica de fixação escleral

    OpenAIRE

    Vianna Filho,Raul de Camargo; Freitas,Lincoln de; Allemann,Norma; Lima,Ana Luísa Hofling de

    2000-01-01

    Objetivo: Avaliar pela biomicrospia ultra-sônica (UBM) o posicionamento, em relação ao sulco ciliar, das alças de lentes intra-oculares (LIO), em uma técnica de fixação escleral, avaliando-se também se dois pontos de fixação são suficientes para que não haja inclinação da parte óptica. Métodos: Dezesseis olhos afácicos foram submetidos a implante LIO por uma mesma técnica de fixação escleral, realizados por um mesmo cirurgião. Um mês após a cirurgia, o posicionamento das alças das LIO foram a...

  5. Avaliação da estabilidade cromática da pintura de íris em próteses oculares polimerizadas por energia de microondas, variando a cor, a tinta e o método de secagem

    OpenAIRE

    Fernandes, Aline Úrsula Rocha [UNESP

    2004-01-01

    A íris artificial é a estrutura da prótese ocular responsável pela sua dissimulação e estética. O propósito do presente trabalho foi avaliar a alteração de cor de tintas utilizadas na pintura de íris em próteses oculares polimerizadas por energia de microondas, variando-se tinta, cor e método de secagem. Para o estudo, foram confeccionados cinco discos em resina termopolimerizável por microondas para cada tinta analisada: acrílica hidrossolúvel, automotiva à base de nitrocelulose, guache hidr...

  6. Pediatric ocular emergencies.

    Science.gov (United States)

    Hamilton, H L

    1999-07-01

    There are few ocular emergencies that are unique to the pediatric patient. Most ocular emergencies are traumatic in origin, and the prognosis is often determined by the extent of the injury. Some congenital anomalies that may present as ocular emergencies are also discussed. The focus of this article is recognition and initial therapy for the more common pediatric ocular emergencies.

  7. Avaliação ocular multimodal em doenças heredodistróficas e degenerativas da retina Multimodal fundus imaging in heredodystrophic and degenerative diseases of the retina

    Directory of Open Access Journals (Sweden)

    Daniela Cavalcanti Ferrara

    2009-10-01

    Full Text Available A tomografia de coerência óptica incorporou-se gradativamente ao contemporâneo arsenal diagnóstico em Oftalmologia, passando a exercer papel fundamental na investigação e condução de doenças oculares, particularmente na especialidade de Retina e Vítreo. A disponibilização comercial da nova geração de aparelhos, chamada de tomografia de coerência óptica "espectral", baseada em conceito físico distinto que permite a aquisição de imagens em alta velocidade, marcou o início de uma nova era desta tecnologia de investigação auxiliar. Adicionalmente, sua recente combinação com o oftalmoscópio de varredura a laser confocal (confocal scanning laser ophthalmoscope vem propiciando a aquisição de imagens tomográficas guiadas em tempo real pelos diferentes modos de imagem (autofluorescência de fundo, reflectância com luz "infravermelha" e angiografia com fluoresceína ou indocianina verde. A avaliação ocular multimodal (multimodal fundus imaging permite a correlação real e minuciosa de achados da morfologia retiniana e do epitélio pigmentar com dados de estudos angiográficos e de autofluorescência ou reflectância, propiciando assim inferências valiosas sobre a fisiologia do tecido. Neste artigo, discutimos brevemente as possíveis implicações da avaliação ocular multimodal na prática da especialidade de Retina e Vítreo.Optical coherence tomography was progressively incorporated to the contemporary diagnostic arsenal in Ophthalmology, playing a crucial role in the diagnosis and management of eye diseases, particularly in the specialty of retina and vitreous. The commercial availability of the new generation of devices, coined "spectral" optical coherence tomography, which is based in a distinct physical concept that permits high-speed image acquisition, launched a new era for this investigative ancillary tool. In addition, the recent combination of this new technology with a confocal scanning laser ophthalmoscope

  8. Afecções oculares prevalentes em crianças de baixa renda atendidas em um serviço oftalmológico na cidade do Recife - PE, Brasil Prevalence of ocular disorders in poor children attending an ophthalmologic clinic in Recife - PE, Brazil

    Directory of Open Access Journals (Sweden)

    Raquel Costa Albuquerque

    2003-12-01

    Full Text Available OBJETIVOS: Descrever os distúrbios visuais diagnosticados em um grupo de crianças carentes, assistidas no serviço oftalmológico do Instituto Materno-Infantil de Pernambuco (IMIP. MÉTODOS: Estudo descritivo, realizado com uma amostra representativa (n=388, selecionada de forma aleatória da clientela de baixa renda na faixa etária de 0 a 15 anos, atendida no período de fevereiro a outubro de 2001 no IMIP. Os diagnósticos, estabelecidos pelos médicos oftalmologistas do serviço, foram classificados de acordo com o CID-10. RESULTADOS: Os distúrbios visuais mais detectados (63,9%, foram os transtornos dos músculos oculares, do movimento binocular, da acomodação e da refração, sendo o estrabismo e a hipermetropia os mais comuns. Seguiram-se os transtornos da conjuntiva e da pálpebra (20,0%, da coróide e da retina (5,1% e do cristalino (3,9. Transtornos da esclerótica e do humor vítreo, glaucoma congênito, cegueira e outros distúrbios foram observados em menor freqüência. CONCLUSÕES: Os distúrbios visuais são comuns nas crianças carentes, sendo os erros de refração e o estrabismo os mais observados na casuística estudada, o que justifica programas de triagem na população infantil.PURPOSE: To describe the commonest visual disorders in a group of poor children attending the Ophthalmology Clinic at the "Instituto Materno-Infantil de Pernambuco (IMIP". METHODS: Descritive study. A randomly selected sample (n=388 of children under the age of 15, from low-income families, seen at IMIP between February and October 2001. Eye disorders were classifical according to the ICD-10 by ophthalmologists in the clinic. RESULTS: Visual problems related to eye muscular disorders (binocular movement, accommodation, refraction were detected in most cases (63.9% and hyperopia and strabismus were the commonest. Disorders of the conjunctiva and eyelid were found in 20% of the cases, followed by choroid and retina (5.1% and the lens (3

  9. Ocular Paintball Injuries

    National Research Council Canada - National Science Library

    Nemet, Arie Y; Asalee, Leena; Lang, Yaron; Briscoe, Daniel; Assia, Ehud I

    2016-01-01

    Background: One of the most alarming ocular injury trends in recent years has been the proliferation of paintball guns and the proportional increase in the number of ocular eye injuries caused by paintballs...

  10. Soroepidemiologia da toxoplasmose e avaliação ocular pela Tela de Amsler, em pacientes da zona rural, atendidos na unidade de saúde do município de Jaguapitã, PR, Brasil

    Directory of Open Access Journals (Sweden)

    Garcia João Luis

    1999-01-01

    Full Text Available O objetivo do trabalho foi avaliar a soroepidemiologia do T. gondii e relato de problemas oculares em pacientes da zona rural que procuraram a unidade de saúde de Jaguapitã, Paraná. Soros de 82 pacientes foram submetidos a reação de Imunofluorescência Indireta, para detectar a presença de anticorpos anti-T. gondii da classe IgG, sendo a soropositividade considerada para diluições 3 1:16. Problemas oculares foram avaliados através da Tela de Amsler. Dos 82 soros avaliados 68 (82,9% foram sororeagentes a toxoplasmose e 14 (17,1% não reagentes. Os títulos mais frequentes foram de 64 (23/33,8% e 256 (16/23,5%, e os maiores títulos foram de 4096 (8/11,8%. O teste da Tela de Amsler revelou 22 (26,8% pacientes que relataram algum tipo de alteração, sendo que o sexo masculino foi um fator de proteção em relação ao sexo feminino (OR = 0,21 0,04 < OR < 0,86 c2 = 4,98 p = 0,02. No presente estudo os fatores de risco avaliados pelo inquérito sócio cultural e epidemiológico não revelaram diferenças estatísticas significativas. Através do presente trabalho observou-se que o T. gondii encontra-se amplamente distribuído na população estudada.

  11. Estudo dos achados oculares na síndrome de Stevens-Johnson em pacientes de centro de referência de atendimento terciário Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center

    Directory of Open Access Journals (Sweden)

    Marciel Dourado Franca

    2009-06-01

    Full Text Available OBJETIVO: Avaliar a epidemiologia, os possíveis fatores desencadeantes, complicações encontradas e as variedades de tratamentos administrados a um grupo de pacientes com complicações oculares secundárias à síndrome de Stevens-Johnson. MÉTODOS: Realizado estudo prospectivo, série de casos com 22 pacientes portadores de síndrome de Stevens-Johnson. Os pacientes foram estudados seguindo um protocolo com o objetivo de se buscar uma história detalhada sobre a doença, suas manifestações sistêmicas e oftalmológicas, bem como o tratamento realizado, dando ênfase aos possíveis fatores desencadeantes. RESULTADOS: Foram avaliados 22 pacientes com síndrome de Stevens-Johnson. Quinze pacientes (68% eram do sexo feminino e 7 (32% do sexo masculino. Dez pacientes eram brancos (45,4%, 9 pardos (22%, 2 negros (9% e 1 amarelo (4,5%. A média de idade foi de 27,1 anos (variação entre 8 e 62 anos. A associação com drogas foi o principal fator etiológico. Em 20 pacientes (90,9% o desenvolvimento da doença esteve associado ao uso de medicações, 1 (4,5% por infecção herpética cutânea e 1 (4,5% idiopático. A dipirona (36,3% foi o agente mais associado à síndrome de Stevens-Johnson seguido por anticonvulsivantes (22,7%, anti-inflamatórios não hormonais (13,6%, sulfonamidas (9,0%, penicilinas (4,5%, espironolactona (4,5% e anticoncepcional injetável (dihidroprogesterona e estradiol (4,5%. Vinte e um pacientes (95,4% desenvolveram complicações oculares e 16 pacientes (72,7% foram submetidos a procedimentos cirúrgicos oftalmológicos. CONCLUSÃO: Os resultados observados neste estudo mostram aspectos epidemiológicos importantes da síndrome de Stevens-Johnson em nosso meio, principalmente em relação à idade, etiologia e complicações.PURPOSE: To evaluate the epidemiology, possible etiologic factors, complications and treatment of a group of patients with ocular complications secondary to Stevens-Johnson syndrome. METHODS

  12. Development of an eye protector for phototherapy on newborns: a technology Desarrollo de un protector ocular para fototerapia en recién nacidos: una tecnología Desenvolvimento de um protetor ocular para fototerapia em recém-nascidos: uma tecnologia

    Directory of Open Access Journals (Sweden)

    Lucía Silva

    2008-02-01

    que no causa incomodidad y se mostró efectivo en las pruebas de radiación.Hiperbilirrubinemia resulta da predisposição de recém-nascidos em produzir bilirrubina e sua capacidade para excretá-la. O tratamento aplicado é a fototerapia, entretanto, uma das complicações é a degeneração da retina pela exposição à luz, sendo essencial providenciar proteção ocular adequada. O objetivo deste estudo é descrever o desenvolvimento de um invento (modelo de utilidade patenteado para a proteção de recém-nascidos em fototerapia. O invento visa substituir a prática corrente improvisada e desconfortável para o bebê, que interfere na relação mãe-bebê. O estudo foi feito avaliando a radiância emitida pela luz da fototerapia. O invento consiste em um modelo de protetor ocular usado durante a fototerapia do recém-nascido, permitindo aproximação mãe-bebê, além de ser de fácil uso, econômico, removível e apropriado ao recém-nascido, pois não causa desconforto e mostrou efetivo nos testes de radiância.

  13. Percepção de expressões faciais em pessoas com esquizofrenia: movimentos oculares, sintomatologia e nível intelectual The perception of facial expressions in people with schizophrenia: eye movements, symptomatology and intelligence

    Directory of Open Access Journals (Sweden)

    Katerina Lukasova

    2007-06-01

    Full Text Available A análise dos padrões dos movimentos oculares em esquizofrênicos mostra que estes apresentam alterações próprias da doença. O objetivo foi avaliar e relacionar as propriedades dos movimentos oculares com o estado clínico e nível intelectual durante observação de faces. Foram avaliados 10 sujeitos com diagnóstico de esquizofrenia e 10 controle, pareados em função de sexo, idade e escolaridade. Foi utilizada a Escala das Síndromes Positiva e Negativa (ESPN, o Teste de Matrizes Progressivas Raven e o Penn Emotion Acuity Test. A busca visual foi registrada com programa EyeGaze®. Resultados mostram que ambos os grupos fixaram mais as faces com conteúdo emocional, sendo o número total de fixações menor entre os pacientes com esquizofrenia. A duração da fixação teve correlação inversa com a pontuação no Raven, PANSS e número de fixação. Parâmetros dos movimentos oculares se correlacionaram com a condição clínica e nível intelectual dos pacientes com esquizofrenia.Analyses of the eye movement patterns of schizophrenics show some specific characteristics underlying the illness. The objective of present study was to evaluate and correlate basic properties of the eye movements with the clinical state and intelligence during the visual scan of faces. 10 outpatient subjects with schizophrenia and 10 controls matched in gender, age and school years were evaluated. The assessment tools were the Positive and Negative Syndrome Scale (PNSS, the Raven's Progressive Matrices Test and the Penn Emotion Acuity Test. The visual scan was registered with the EyeGaze® program. Both groups showed more fixations for stimuli with emotional expression, with significantly smaller overall number of fixations for the schizophrenic subjects group. Duration of fixations was inversely correlated with score in the Raven Test, PANSS and number of fixations. The properties of the eye movements showed correlation with the clinical condition and

  14. Estudo dos achados oculares na síndrome de Stevens-Johnson em pacientes de centro de referência de atendimento terciário

    OpenAIRE

    Franca, Marciel Dourado; Lima, Jane Palma Galrão; Freitas, Denise de; Cunha, Marcelo; Gomes, José Álvaro Pereira [UNIFESP

    2009-01-01

    OBJETIVO: Avaliar a epidemiologia, os possíveis fatores desencadeantes, complicações encontradas e as variedades de tratamentos administrados a um grupo de pacientes com complicações oculares secundárias à síndrome de Stevens-Johnson. MÉTODOS: Realizado estudo prospectivo, série de casos com 22 pacientes portadores de síndrome de Stevens-Johnson. Os pacientes foram estudados seguindo um protocolo com o objetivo de se buscar uma história detalhada sobre a doença, suas manifestações sistêmicas ...

  15. Arteterapia na assistência de enfermagem em oncologia: produções, expressões e sentidos entre pacientes e estudantes de graduação Terapia con arte en la ayuda de enfermería en oncología: producciones, expresiones y sentidos entre pacientes y estudiantes de Graduación Art therapy in oncology's nursing care: productions, expressions and meanings among patients and graduation students

    Directory of Open Access Journals (Sweden)

    Izabel Cristina Falcão Juvenal Barbosa

    2007-06-01

    Full Text Available O objetivo deste artigo é relatar a experiência vivida por um grupo de alunas do Curso de Graduação em Enfermagem da Universidade Federal do Ceará, na disciplina Administração do Processo de Trabalho em Enfermagem II, na administração do ócio dos pacientes em um hospital de Fortaleza-CE. A experiência didática foi uma representação plástica a partir do Quadro de Referência Cognitivo-Comportamental realizado em abril de 2002, e teve como sujeitos sete pacientes e seis alunas de enfermagem. A criatividade artística dos pacientes fluiu em conseqüência do diálogo do artista com sua produção. A análise das produções artísticas foi complementada pelas observações das alunas. As obras produzidas foram interpretadas com a ajuda do teste de cores de Lüscher o que permitiu inferir o comportamento e os sentimentos exteriorizados nas cores variadas selecionadas pelos pacientes.El objetivo de este artículo es relatar la experiencia vivida por un grupo de alumnas del Curso de Graduación en Enfermería de la Universidad Federal del Ceará (Brasil, en la disciplina Administración del Proceso de Trabajo en Enfermería II, en la administración de la ociosidad de los pacientes en un hospital de Fortaleza - Ceára, Brasil. La experiencia didáctica fue una representación plástica desde el Cuadro de Referencia Cognoscitivo y del Comportamiento realizado en abril de 2002, y tenía como sujetos siete pacientes y seis alumnas de enfermería. La creatividad artística de los pacientes fluyó en consecuencia del diálogo del artista con su producción. El análisis de las producciones artísticas fue complementado por las observaciones de las alumnas. Las obras producidas habían sido interpretadas con la ayuda de la prueba de colores de Lüscher que permitió inferir en el comportamiento y en las sensaciones exteriorizadas en los colores variados seleccionados por los pacientesThe objective of this article is to report the experience

  16. The pediatric patient at a maxillofacial service: eye prosthesis O paciente pediátrico em um serviço de prótese bucomaxilofacial: prótese ocular

    Directory of Open Access Journals (Sweden)

    Beatriz Silva Câmara Mattos

    2006-09-01

    comprometem o desenvolvimento normal da região orbitária. A literatura relacionada à etiologia congênita ou adquirida, devido a trauma ou doença, demonstra a necessidade da prevenção e da detecção precoce para minimizar as seqüelas e os distúrbios de crescimento orbital. A reabilitação implica a instalação de uma prótese ocular visando favorecer o desenvolvimento harmonioso da região. Com o objetivo de caracterizar o perfil do paciente infantil foi realizado um levantamento junto ao Setor de Prótese Ocular do Ambulatório da Disciplina de Prótese Bucomaxilofacial da FOUSP abrangendo o período de 1988 a 2003. As 124 (14,02% crianças registradas encontravam-se distribuídas em 64 (51,62% na faixa etária de 0 a 7 anos e 60 (48,38% na de 8 a 13 anos de idade, sendo 59 meninas e 65 meninos. A análise estatística revelou que a variação das ocorrências dos gêneros masculino e feminino nas faixas etárias não é significante (p = 0.069. Entretanto, a etiologia da perda variou segundo as faixas etárias consideradas, com um nível de significância de 0,01, apresentando uma maior prevalência de distúrbios congênitos e patológicos na faixa etária mais jovem e trauma na mais velha. A etiologia alterou-se de acordo com os gêneros com uma significância de 0,05, tendo as meninas apresentado três vezes menos trauma que os meninos na faixa etária mais velha. A necessidade de tratamento protético apresentou-se igualmente distribuída ao longo da infância e as perdas oculares que implicam reabilitação protética ocorreram igualmente nos gêneros masculino e feminino. Entretanto, a etiologia da perda ocular variou em função do gênero e da faixa etária considerada.

  17. Posicionamento palpebral superior e inferior em diferentes graus de rotação ocular ao longo do meridiano vertical Upper and lower eyelid position in different degrees of downgaze and upgaze

    Directory of Open Access Journals (Sweden)

    Dante Augusto Mastropietro

    2009-12-01

    Full Text Available OBJETIVO: Quantificar a relação entre o posicionamento do olho e das pálpebras, em diferentes posições do olhar, ao longo do meridiano vertical, em indivíduos normais. MÉTODOS: Foi quantificada a posição das pálpebras superior e inferior e do olho, de dez indivíduos normais, por meio do processamento da imagem da fenda palpebral usando o programa NIH Image. Foram medidas as distâncias margem-centro pupilar superior e inferior em sete posições do olhar ao longo do meridiano vertical, ou seja -30, -20, -10, 0, +10, +20 e +30 graus (sinais: negativos infraducção e positivos supraducção. RESULTADOS: Em relação à distância margem superior-centro da pupila, nota-se que o maior valor é obtido na posição primária do olhar, ou seja, tanto quando se olha para cima, como para baixo, essa distância diminui. A redução na distância margem superior-centro da pupila é um pouco maior no olhar para cima. Em relação à distância margem inferior-centro da pupila, nota-se que o valor é maior no olhar para cima e menor no olhar para baixo, em relação à posição primária do olhar. No que tange à fenda palpebral, pode-se notar que no olhar para cima a fenda aumenta até 20 graus de rotação ocular. No olhar para baixo, ela diminui. CONCLUSÃO: Os dados do presente trabalho mostram que a altura da fenda palpebral varia de acordo com a amplitude da mirada vertical e que considerações sobre o valor da magnitude da distância entre a margem palpebral e o centro da pupila devem levar em conta o grau de rotação ocular vertical.PURPOSE: To quantify the relation between eye and eyelids placement in different positions during downgaze and upgaze in healthy subjects. METHODS: The position of the eye and eyelids of 10 healthy individuals was quantified by palpebral fissure image processing with NIH Image software. Upper and lower mid-pupil margin distance was measured in 7 positions: -30, -20, -10, 0, +10, +20 and +30 degrees

  18. Prevalência de infecção por Chlamydia tracomatis em amostras oculares de pacientes com conjuntivite em laboratório de genética e biologia molecular na região metropolitana de Florianópolis Prevalence of infection by chlamydia trachomatis in ocular samples of patients with conjunctivitis in genetic and molecular biology laboratory from metropolitan area of Florianópolis, Brazil

    Directory of Open Access Journals (Sweden)

    Marcos de Oliveira Machado

    2009-08-01

    Full Text Available Objetivo: Conhecer a prevalência de infecção ocular em amostras de raspado conjuntival causada por C. trachomatis, no período de janeiro de 2004 a junho de 2007 em laboratório de Genética e Biologia Molecular da região metropolitana de Florianópolis, SC. Métodos: Realizou-se um estudo transversal e descritivo, envolvendo todos os casos de conjuntivite registrados no banco de dados do Laboratório de Genética e Biologia Molecular (DNAnálise de janeiro de 2004 a junho de 2007. Foi observada a positividade de C. tracomatis nas amostras coletadas de raspado ocular. Resultados: Dos 660 exames realizados foram detectados 359 casos positivos (54,4%, sendo a maior parte do sexo feminino (66,3%. A prevalência foi maior na faixa etária de zero a 15 anos em pacientes de ambos os sexos, sendo 55,8% para o sexo masculino e 62,5% para o sexo feminino. Verificou-se um grande aumento de casos positivos no primeiro semestre do ano de 2006, representando 79,2% de todos os pacientes analisados. Conclusão: Houve um aumento no número de casos de conjuntivite na região metropolitana de Florianópolis no ano de 2006, causada pela C. trachomatis no laboratório de Genética e Biologia Molecular. O grande aumento de casos verificados sugere a necessidade da intensificação das ações de vigilância epidemiológica do tracoma nessa região para confirmar clinicamente o aumento da prevalência do tracoma.Objective: To estimate the prevalence of ocular infection by Chlamydia trachomatis in conjuctival material, from january 2004 to june 2007 at Genetic and Molecular Biology Laboratory from Florianópolis Metropolitan area, SC. Methods: A cross-sectional and descriptive study involving all cases of conjunctivitis using the database of Genetic and Molecular biology Laboratory (DNAanálises recorded in the period from january 2004 to june 2007 was carried out. The positivity to C. trachomatis in conjunctival material was observed. Results: A total of 660

  19. Tonometria, paquimetria e comprimento axial ocular em cães glaucomatosos submetidos à ablação uveal intravítrea Tonometry, pachymetry and globe axial lenght in glaucomatous dogs submitted to intravitreal uveal ablation

    Directory of Open Access Journals (Sweden)

    C.V.S. Brandão

    2007-08-01

    Full Text Available Estudaram-se as alterações tonométricas, paquimétricas e de comprimento axial em cães com glaucoma submetidos à ablação uveal intravítrea. Foram avaliados 13 olhos irreversivelmente cegos de cães que apresentavam glaucoma crônico unilateral, nos quais realizou-se a ablação uveal intra-vítrea, por meio de injeção na câmara vítrea de 0,5ml de sulfato de gentamicina (40mg/ml associado a 0,3ml de fosfato de dexametasona (4mg/ml. As mensurações da pressão intra-ocular (Po, espessura corneana e eixo axial com tonometria de aplanação, paquimetria ultra-sônica e ultra-sonografias modos A e B foram realizadas no dia da ablação (M0 e após uma (M1, quatro (M4, oito (M8, 12 (M12, 24 (M24 e 48 semanas (M48. A Po diminuiu significativamente em todos os momentos em relação ao M0, com aumento da espessura corneana ao longo do experimento. Nas avaliações ultra-sonográficas notou-se diminuição significativa do bulbo ocular a partir de M4, com medidas ultra-sonográficas modo A significativamente maiores que as do modo B. O procedimento foi efetivo na redução da Po e na diminuição do eixo axial, demonstrando ser viável no controle do glaucoma crônico em olhos irreversivelmente cegos, e ser uma alternativa à enucleação e inserção de prótese ocular.Changes in tonometry, pachymetry and globe axial length in glaucomatous dogs submitted to intravitreal uveal ablation were studied. Thirteen irreversible blind canine eyes were evaluated. They presented unilateral chronic glaucoma, in which intravitreal uveal ablation was performed, through vitreous chamber injection of 0.5ml of gentamicin sulfate solution (40mg/ml with 0.3ml of dexametazon dissodic phosphate (4mg/ml. The measurements of intraocular pressure (IOP, corneal thickness and globe axial length with aplanation tonometry, ultrasound pachymetry and A and B-mode ultrasound scan were made on the day of the procedure (M0, and on the next day (M1, four (M4, eight (M8, 12

  20. Radiation treatment of early vocal cord carcinoma. Eighteen years experience at "Instituto de Oncologia y Radioterapia de Mar del Plata".

    Science.gov (United States)

    Castro Vita, H

    1990-01-01

    A detailed retrospective analysis of 260 patients with T 1 NO MO vocal cord carcinoma treated at "Instituto de Oncologia y Radioterapia de Mar del Plata" from 1967 to 1985 was performed. The majority of the patients were in the age range of 50 to 79 years, and 79% were males. The overall observed three year tumor free survival was 85.3%. When survival rate was adjusted for intercurrent disease and second primary tumor death, the 3 year tumor free survival was 92%. Sixty two percent of the patients (17/27) undergoing surgical salvage for recurrence, were controlled. Second primary tumors were seen in 18 patients (6.9%). It is emphasized the importance of close follow up to diagnose as early as possible both the vocal cord recurrence and the second primary tumors.

  1. Uso de terapias integrativas e complementares por pacientes em quimioterapia

    Directory of Open Access Journals (Sweden)

    Julyane Felipette Lima

    2015-09-01

    Full Text Available Objetivo: Conhecer as terapias integrativas e complementares utilizadas pelos pacientes em quimioterapia oncológica. Metodologia: Estudo qualitativo, realizado com seis pacientes oncológicos em tratamento quimioterápico, em um serviço de oncologia do sul do Rio Grande do Sul, Brasil. Os dados foram coletados por meio de entrevista, em junho de 2010, sendo a análise de conteúdo tipo temática. Resultados: As terapias apontadas neste estudo foram a homeopatia, a fitoterapia e as plantas medicinais e percebeu-se que elas aumentam a sensação de bem-estar, possibilitam o estabelecimento de vínculos positivos com profissionais da saúde, e fazem parte do saber popular e estão interligadas ao conhecimento científico. Conclusões: Apreende-se que uso de terapias integrativas e complementares em oncologia permite a aproximação do profissional enfermeiro com o paciente em quimioterapia, conhecendo-o em sua complexidade.

  2. Estudo das modificações oculares induzidas pelo implante estromal do anel de Ferrara em portadores de ceratocone Study of the ocular changes after stromal Ferrara ring implantation in patients with keratoconus

    Directory of Open Access Journals (Sweden)

    Paulo Ferrara de Almeida Cunha

    2003-08-01

    Full Text Available OBJETIVO: Comparar a acuidade visual com e sem correção, ceratometria média e equivalente esférico antes e após o implante do anel intraestromal de Ferrara em pacientes portadores de ceratocone intolerantes a lentes de contato. MÉTODOS: Foram analisados os primeiros 400 olhos com ceratocone tratados com o implante do anel de Ferrara, levando-se em consideração as alterações obtidas na curvatura corneana, acuidade visual e refração, bem como a estabilidade dos resultados no primeiro ano. RESULTADOS: Nos 400 olhos estudados, observamos redução média na curvatura corneana de 4,18 D, o equivalente esférico diminuiu 4,65 D quando comparamos os valores obtidos no pré-operatório e os do último exame realizado. A AV média não corrigida foi a que sofreu maior alteração, passando de PURPOSE: To compare the changes in corneal curvature, visual acuity and spherical equivalent before and after the implantation of the intrastromal corneal Ferrara ring in contact lens intolerant keratoconus patients. METHODS: The first 400 eyes treated with the Ferrara ring were evaluated according to the alterations obtained in the corneal curvature, visual acuity and refraction after surgery, as well as the stability of the results in the first year. RESULTS: In the 400-studied eyes, there was a mean reduction of 4.18 D in keratometry and 4.65 D in spherical equivalent. The mean uncorrected visual acuity showed the greatest improvement varying from less than 20/400 before to 20/100 after surgery. The mean BSCVA was 20/50 after the surgery. The more advanced keratoconus (III/IV groups showed the greatest reduction in keratometry. The correction remained stable along the period of the study in all groups. CONCLUSION: The Ferrara ring showed to produce reduction of myopia, regularization of the cornea and consequent corrections of the irregular astigmatism, disappearance of the keratoconic pattern and a significant improvement of the corrected and

  3. Estudo da microbiota fúngica da conjuntiva ocular em portadores de hanseníase e seus comunicantes Study of ocular fungal microbiota in patients with Hansen's disease and in individuals who deal with them

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    Procópio Miguel dos Santos

    2006-12-01

    Full Text Available OBJETIVO: Investigar a microbiota fúngica de pacientes portadores de hanseníase residentes no hospital-colônia e seus comunicantes. MÉTODOS: Foram estudados por meio da cultura em meio de ágar-Saboraud-dextrose, o material do fórnice conjuntival, de sessenta e um pacientes portadores de hanseníase, residentes no hospital-colônia de Goiânia e 25 indivíduos que residiam ou trabalhavam com os referidos pacientes, no mínimo há cinco anos. RESULTADOS: Nos portadores de hanseníase foram isolados fungos da conjuntiva de 12 pacientes (19,67%, sendo o gênero Candida o mais isolado, e no grupo controle de 5 indivíduos (20%, em que o gênero mais isolado foi Penicillium spp. CONCLUSÃO: Candida foi o gênero predominante na flora conjuntival dos portadores de hanseníase: fato que poderia ser explicado pela imunodeficiência celular que estes pacientes apresentam, além do olho seco e uso prolongado de antibiótico.PURPOSE: To study the conjunctival fungal flora of patients with leprosy who live in the colony hospital and of those who deal with "Hansen" patients. METHODS: Sixty-one eyes (61 patiets with Hansen's disease and twenty-five heathy eyes (25 individuals of individuals who deal with patients were investigated. RESULTS: Conjunctival fungi growth occurred in 19.67% and 20% of the patients and healthy individuals, respectively. There was no significant difference (p<0.05 regarding fungi percentage of fungi isolated from the conjunctiva between both groups. Candida ssp was the most frequent fungus isolated from the conjunctiva of patients with Hansen's disease, whereas Penicillium spp was the most frequent fungus isolated from the group of people who deal with these patients. CONCLUSION: The most frequent yeast isolated from conjunctival samples of leprosy patients was Candida, which could be explained by cellular immunodeficiency of these patients, associated with dry eye and the prolonged use of antibiotics.

  4. Uso tópico do inteferon alfa-2b para neoplasia escamosa da superficie ocular em um caso de paciente com xeroderma pigmentoso

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    Nayara Queiroz Cardoso Pinto

    Full Text Available Resumo Relato de um caso clínico de Xeroderma Pigmentoso com carcinoma espinocelular de conjuntiva bilateral que apresentou regressão importante das dimensões tumorais com o uso de Interferon alfa-2b tópico. Relato de caso: Paciente feminina com Xeroderma Pigmentoso em estágio avançado, com ausência de pele sadia, tendo sido submetida a cerca de 60 exéreses de lesões de pele malignas. A paciente compareceu com tumoração conjuntival em ambos os olhos, correspondendo a carcinoma espinocelular de conjuntiva e neoplasia intraepitelial de conjuntiva em olho esquerdo. Devido as dificuldades cirúrgicas, alta taxa de recidiva e elevada probabilidade de formação de simbléfaro foi-se iniciado terapêutica com Interferon alfa-2beta 1.000.000 unidades tópico, obtendo-se bons resultados com importante regressão do tamanho da lesão e resolução dos sintomas. Conclusão: O uso tópico de interferon alfa-2beta em neoplasia escamosa de conjuntiva, mostrou-se uma boa opção terapêutica em situações de elevado risco cirúrgico e de complicações pós operatórias.

  5. Avaliação da sensibilidade ao contraste e da estereopsia em pacientes com lente intra-ocular multifocal Contrast sensitivity and stereopsis in pseudophakic patients with multifocal intraocular lens

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    Filipe de Oliveira

    2005-08-01

    Full Text Available OBJETIVO: Avaliar a sensibilidade ao contraste e a acuidade estereoscópica em pacientes pseudofácicos, que receberam implante bilateral de lente intra-ocular multifocal. MÉTODOS: Prospectivamente foram realizados testes de sensibilidade ao contraste com o uso da tabela Pelli-Robson e teste de acuidade estereoscópica com emprego do Titmus Stereo Test, em 20 pacientes com implante bilateral de lente intra-ocular multifocal Acrysof Restor®, no pós-operatório de 1 a 2 meses e sem uso de qualquer correção óptica. RESULTADOS:O teste de sensibilidade ao contraste binocular demonstrou que 6 pacientes (30% apresentaram 1,80 unid. log, 13 (65% 1,65 e 1 (5% 1,50. No teste monocular, ocorreram as seguintes respostas: 17 pacientes (85% 1,65 unid. log e 3 (15% 1,50 para o teste do olho direito. O teste do olho esquerdo mostrou que 16 pacientes (80% apresentaram 1,65 unid. log e 4 (20% 1,50. A média e o desvio-padrão da sensibilidade ao contraste testada binocularmente foi 1,69 (±0,08, ao passo que monocularmente foi 1,63 (±0,05 para OD e 1,62 (±0,06 para OE. O teste de acuidade estereoscópica revelou que 12 pacientes (60% obtiveram 40", 6 (30% 50" e 2 (10% 60", com média de 45" e desvio-padrão de ±6,88". CONCLUSÃO: A lente intra-ocular empregada no estudo, proporcionou resultados de sensibilidade ao contraste e acuidade estereoscópica compatíveis e de acordo com critérios de normalidade estabelecidos anteriormente por outros estudos em grupos de pacientes fácicos e pseudofácicos, e portanto, impacto positivo na funcionalidade visual.PURPOSE: To evaluate the contrast sensitivity and stereopsis tests in patients who underwent bilateral implantation of multifocal intraocular lens. METHODS: Tests of contrast sensitivity using the Pelli-Robson chart and stereopsis evaluation with the Titmus Stereo Test were performed in 20 patients 30-60 days after the bilateral implantation of Acrysof Restor® multifocal intraocular lens. RESULTS: The

  6. Potencial evocado miogênico vestibular ocular e cervical simultâneo em indivíduos com hiporreflexia vestibular e em indivíduos com doença de Ménière,

    OpenAIRE

    Silva,Tatiana Rocha; de Resende, Luciana Macedo; Santos,Marco Aurélio Rocha

    2017-01-01

    Abstract Introduction: The vestibular evoked myogenic potential is a potential of mean latency that measures the muscle response to auditory stimulation. This potential can be generated from the contraction of the sternocleidomastoid muscle and also from the contraction of extraocular muscles in response to high-intensity sounds. This study presents a combined or simultaneous technique of cervical and ocular vestibular evoked myogenic potential in individuals with changes in the vestibular s...

  7. Alterações oculares na hanseníase, observadas em pacientes ambulatoriais do serviço de referência da cidade de Rio Branco, Acre - Brasil Eye lesions observed in outpatients of a leprosy reference center at Rio Branco, state of Acre, Brazil

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    Renaldo Duarte Moreno

    2003-12-01

    Full Text Available OBJETIVO: Determinar a prevalência das alterações oculares em pacientes de hanseníase ativa ou inativa, acompanhados em serviço de referência. MÉTODOS: O estudo transversal constou de exame ocular e levantamento de dados demográficos e clínico-epidemiológicos, em serviço de referência da cidade de Rio Branco (Acre, no período de outubro de 2001 a abril de 2002. RESULTADOS: Foram examinados 254 pacientes, com média de idade de 41,9 anos; 70,1% do sexo masculino e 29,9% do feminino; 73,6% residentes da área urbana e 76,8% de formas multi e 23,2% de paucibacilares. Anormalidades de anexos oculares foram descritas em 49,6% (n=126 dos casos e do globo ocular em 39,4% (n=100 dos casos, sendo as mais freqüentes: hipoestesia corneana, catarata, madarose, manchas hipercrômicas, hipolacrimejamento e ceratite ponteada. As lesões oculares (74,4% tiveram freqüências desiguais (rPURPOSE: To determine the prevalence of eye lesions in patients with active and non active leprosy who are being accompanied in a reference center. METHODS: The transverse study consisted of ocular examinations and the study of demographic and clinical-epidemiological data, in the reference center in the city of Rio Branco, AC (Brazil. The study was conducted between October of 2001 and April of 2002. RESULTS: Two hundred fifty-four patients were examined, the average age was 41.9 years, 70.1% were males and 29.9% females; 73.6% were from the urban area, 76.8% were of the multibacillary form and 23.2% were of the paucibacillary form. Abnormalities of the ocular annexes were observed in 49.6% of the patients (n=126 and of the ocular globe in 39.4% (n=100, the most frequent being hypoesthesia of the cornea, cataract, madarosis, hiperchromic patches, hypolacrimation, and punctate keratitis. The eye lesions (74.4% had unequal frequencies (r<0.0001, being predominant among those older than 40 years (48.4%, against 26.0% in those under 40 years of age, multibacillary

  8. Lesões oculares por álcali em cães: efeitos da acetilcisteína e do soro sangüíneo

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    Carla Freitas Campos

    2003-01-01

    Full Text Available Estudaram-se lesões oftálmicas promovidas pelo contato com Hidróxido de sódio (NaOH a 3M em 42 cães, divididos em três grupos, tratados com soro sangüíneo autógeno, da acetilcisteína e solução salina balanceada (G1, G2 e G3, respectivamente. Não foram encontradas diferenças mediante a comparação entre os grupos, considerando-se parâmetros clínicos e microscópicos.

  9. Manifestações oculares em pacientes que tiveram desnutrição nos primeiros seis meses de vida Ocular manifestations in patients who had malnutrition in the first six months of life

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    Alessandra Pereira Dantas

    2005-12-01

    Full Text Available OBJETIVOS: Investigar possíveis alterações oftalmológicas em pacientes que tiveram desnutrição grave durante os primeiros seis meses de vida. MÉTODOS: Foram analisados 182 olhos de 91 crianças entre 2 e 11 anos que tiveram desnutrição grave durante os primeiros seis meses de vida (grupo estudo. Como grupo controle foram incluídas 88 crianças, selecionadas aleatoriamente segundo características similares de idade, gênero, condições econômicas e demográficas. RESULTADOS: Observou-se, de forma significante, no grupo estudo, maior freqüência de crianças com acuidade visual de 0,3 a 0,1 e menor que 0,1 (11,5% versus 0,7% - p PURPOSE: To investigate possible ophthalmologic alterations in patients who had severe malnutrition during the first six months of life. METHODS: 182 eyes of 91, 2 to 11-year-old, children who had had severe malnutrition during the first six months of life (study group were analyzed. As a control group 88 children selected according to similar characteristics of age, gender, demographic and economic conditions were included. RESULTS: In the study group, a higher frequency of children with visual acuity from 0.3 to 0.1 and less than 0.1 (11.5% versus 0.7% - p<0.0001 was observed. There was a higher frequency of astigmatism and myopia in the study group. A higher frequency of astigmatism of one diopter or more in the study group (p<0.0001 was also observed. The fundoscopic alterations were pale optic nerve (2.2%, increased disc cup (4.4%, increased vascular tortuosity (6.6%, alteration of retina color (13.2% and retinal pigment epithelium cell atrophy (12.0%. CONCLUSIONS: The present data support the concept that early malnutrition interferes in the individual's visual health. Further studies are necessary to establish a more precise cause-effect relationship.

  10. Genetics Home Reference: ocular albinism

    Science.gov (United States)

    ... Facebook Twitter Home Health Conditions ocular albinism ocular albinism Printable PDF Open All Close All Enable Javascript to view the expand/collapse boxes. Description Ocular albinism is a genetic condition that primarily affects the ...

  11. Partnership of the Sociedade Brasileira de Oncologia Pediátrica and International Society of Pediatric Oncology to improve nutritional care for children with cancer in Brazil.

    Science.gov (United States)

    Viani, Karina; Filho, Vicente Odone; Ferman, Sima; Fonseca, Teresa Cristina Cardoso; Oliveira, Vanessa da Cunha; Lemos, Priscila Dos Santos Maia; Barr, Ronald D; Ladas, Elena J

    The authors present a proposal of a partnership between the Sociedade Brasileira de Oncologia Pediátrica (SOBOPE) and the International Society of Pediatric Oncology (SIOP) to promote the standardization and improvement of nutritional care of kids under cancer treatment in Brazil. The results of the first meeting in Brazil as well as plans for future meetings are described. Copyright © 2017 Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular. Published by Elsevier Editora Ltda. All rights reserved.

  12. Epidemiology of Ocular Toxoplasmosis

    NARCIS (Netherlands)

    Petersen, E.; Kijlstra, A.; Stanford, M.

    2012-01-01

    Retinal infection with Toxoplasma gondii is the most important cause of posterior uveitis, whereby prevalence and incidence of ocular symptoms after infection depend on socio-economic factors and the circulating parasite genotypes. Ocular toxoplasmosis is more common in South America, Central

  13. Paintball ocular injuries.

    Science.gov (United States)

    Kruger, L P; Acton, J K

    1999-03-01

    Six cases of ocular injury following paintball injuries sustained during war games are described. A CO2-powered rifle shoots a 14 mm plastic-coated paintball at participants. The muzzle velocity of the gun is 250 ft/sec (76 m/sec). Locally manufactured paintballs are harder than the more expensive imported varieties and may account for the severity of our reported injuries. Six patients presented to a retinal specialist with various ocular injuries, predominantly of the posterior pole. All patients were young males. There were no cases of ocular penetration. A variety of retinal pathologies was noted, with three cases requiring surgery; however this did not significantly improve the visual outcome. These cases highlight the severe ocular injuries that may occur from paintball injuries. Recommendations to avoid ocular injury are made.

  14. Ocular findings in Brazilian identical twins with Cohen syndrome: case report Achados oftalmológicos em gêmeos idênticos brasileiros com síndrome de Cohen: relato de caso

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    Priscila Hae Hyun Rim

    2009-12-01

    Full Text Available A case of identical male twins with Cohen syndrome who present multiple ophthalmic findings is reported. The patients were identical 16 year-old twin boys who showed down slanting eyelids, mild ptosis, high-grade myopia, small cortical lens opacities, posterior subcapsular cataracts, myotic and corectopic pupils with poor dilation due to focal iris atrophy and retinochoroidal dystrophy. Ophthalmologists must be aware of the ocular and systemic findings of Cohen syndrome in the evaluation of young patients with mental retardation and visual impairment.Relata-se caso de gêmeos idênticos com síndrome de Cohen que apresentam múltiplos achados oftalmológicos. Os pacientes eram gêmeos idênticos, do sexo masculino, que apresentavam pálpebras em forma de onda, ptose moderada, alta miopia, opacidades cristalinianas corticais discretas, catarata subcapsular posterior, pupilas mióticas e corectópicas com pobre dilatação devido à atrofia focal de íris, além de distrofia retinocoroidiana. Os oftalmologistas devem estar atentos quanto aos achados oftalmológicos e sistêmicos da síndrome de Cohen na avaliação de pacientes jovens com retardo mental e baixa visão.

  15. Eye-hand preference dissociation in obsessive-compulsive disorder and dyslexia Dissociação da preferência ocular e manual em pacientes com transtorno obsessivo-compulsivo e dislexia

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    Marilena Occhini Siviero

    2002-06-01

    avaliação da lateralidade de Zazzó versão reduzida de Granjon. Os resultados mostraram a preferência pela mão direita de 84,6% nos disléxicos, 100% nos normais e 80% em TOC. A preferência ocular pelo olho direito foi de 69,2% nos disléxicos, 73,3% nos normais e apenas 35% nos TOC, com significância de p=0,01 quando comparada aos outros dois grupos.A preferência da mão esquerda pelo grupo de pacientes com TOC (25% foi também significante quando comparada com os resultados da população brasileira em geral (4% ou da população inglesa (4,5%. É possível que esta dominância cruzada seja responsável, em parte, pelas dificuldades visuo-espaciais e construcionais observadas no TOC.

  16. Ocular Emergencies: Red Eye.

    Science.gov (United States)

    Tarff, Andreina; Behrens, Ashley

    2017-05-01

    "Red eye" is used as a general term to describe irritated or bloodshot eyes. It is a recognizable sign of an acute/chronic, localized/systemic underlying inflammatory condition. Conjunctival injection is most commonly caused by dryness, allergy, visual fatigue, contact lens overwear, and local infections. In some instances, red eye can represent a true ocular emergency that should be treated by an ophthalmologist. A comprehensive assessment of red eye conditions is required to preserve the patients visual function. Severe ocular pain, significant photophobia, decreased vision, and history of ocular trauma are warning signs demanding immediate ophthalmological consultation. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Aspectos psicológicos da recidiva em Oncologia Pediátrica: uma revisão integrativa

    OpenAIRE

    Marina Noronha Ferraz de Arruda-Colli; Manoel Antônio dos Santos

    2015-01-01

    Este estudio tuvo como objetivo comprender cómo los aspectos psicológicos de la recaída del cáncer infantil han sido investigados en la literatura científica. Se realizó una revisión integradora, con la búsqueda electrónica a partir de las bases de indexa - ción PubMed, LILACS, SciELO, PsycINFO y Cochrane Library, a partir de los siguientes descriptores: neoplasias, recaída, recaída del cáncer, niño, familia, padres, psicolo - gía infantil. Se plantearon 473 artículos. Luego de...

  18. Aspectos psicológicos da recidiva em Oncologia Pediátrica: uma revisão integrativa

    Directory of Open Access Journals (Sweden)

    Marina Noronha Ferraz de Arruda-Colli

    2015-01-01

    Full Text Available Este estudio tuvo como objetivo comprender cómo los aspectos psicológicos de la recaída del cáncer infantil han sido investigados en la literatura científica. Se realizó una revisión integradora, con la búsqueda electrónica a partir de las bases de indexa - ción PubMed, LILACS, SciELO, PsycINFO y Cochrane Library, a partir de los siguientes descriptores: neoplasias, recaída, recaída del cáncer, niño, familia, padres, psicolo - gía infantil. Se plantearon 473 artículos. Luego de la aplicación de los criterios de inclusión/exclusión, 14 publicaciones permanecieron en la selección final. Se eviden - cia la predominancia de los delineamientos empíricos con enfoque cuantitativo. Las principales estrategias de afrontamiento utilizadas por los pacientes y sus cuidado - res, y las intervenciones que promuevan la calidad de vida son descritos. Una visión panorámica del campo de la investigación evidencia la necesidad de hacer frente a la incertidumbre y organizarse para afrontar el reinicio del tratamiento. Comprender estas variables puede auxiliar a la organización de la atención integral a la familia.

  19. Politicas públicas em oncologia: refletindo sobre a atuação da Terapia Ocupacional

    OpenAIRE

    Silva, Ana Cristina Cardoso da; Santos, Andréa Rizzo dos [UNESP

    2012-01-01

    A Política Nacional de Atenção Oncológica almeja o acesso e atendimento integral além de uma maior efetividade e efi ciência no controle do câncer. Assim, diversas ações, serviços e profi ssionais são exigidos para dar a assistência necessária. A respeito da atuação da Terapia Ocupacional, nota-se que a profi ssão não é especifi cada, e não tem a atuação regulamentada. Sendo assim, o objetivo principal do presente estudo foi identifi car a inserção, atuação e ampliação do campo de trabalho da...

  20. Survival results in five malignant neoplasms separated by a decade at Institut Català d'Oncologia, Spain.

    Science.gov (United States)

    Germá-Lluch, José Ramón; Petriz, Lourdes; Lopez, Pau; Asensio, Esther

    2018-02-23

    Five years' data relative survival (RS) is presented in 3 solid tumours: breast, colorectal (CRC) and lung and 2 haematologic neoplasms: large B cell lymphoma (NHL-B) and multiple myeloma (MM) treated at Institut Català d'Oncologia between 2010-2011 in comparison with the results obtained in a historical special cohort from 1998-1999. A database was created in a common safe and accessible repository. We have introduced more than 5,000 medical records. To analyse the results the statistical package R ® was used for RS. The overall RS at 5 years for 2010-2011 was: CRC 67%, breast 93.6%, lung 28%, NHL-B 68% and MM 62%, while for 1998-1999 is was: CRC 61.8%, breast 88.8%, lung 23.1%, NHL-B 67.7%, and MM 43.4%. Comparative results have shown a 5% overall improvement in RS for the 3 solid tumours, a significant increase in MM and a stabilisation in the NHL-B. Copyright © 2017 Elsevier España, S.L.U. All rights reserved.

  1. Challenging ocular image recognition

    Science.gov (United States)

    Pauca, V. Paúl; Forkin, Michael; Xu, Xiao; Plemmons, Robert; Ross, Arun A.

    2011-06-01

    Ocular recognition is a new area of biometric investigation targeted at overcoming the limitations of iris recognition performance in the presence of non-ideal data. There are several advantages for increasing the area beyond the iris, yet there are also key issues that must be addressed such as size of the ocular region, factors affecting performance, and appropriate corpora to study these factors in isolation. In this paper, we explore and identify some of these issues with the goal of better defining parameters for ocular recognition. An empirical study is performed where iris recognition methods are contrasted with texture and point operators on existing iris and face datasets. The experimental results show a dramatic recognition performance gain when additional features are considered in the presence of poor quality iris data, offering strong evidence for extending interest beyond the iris. The experiments also highlight the need for the direct collection of additional ocular imagery.

  2. Pediatric Ocular Trauma

    Science.gov (United States)

    ... Frequently Asked Questions Español Condiciones Chinese Conditions Pediatric Ocular Trauma What causes eye injuries ? Injuries to the ... only the eyelid but the structures that drain tears from the eye. Lacerations of the eyelid or ...

  3. Ocular rosacea: a review

    Directory of Open Access Journals (Sweden)

    Ana Carolina Cabreira Vieira

    2012-10-01

    Full Text Available Rosacea is a prevalent chronic cutaneous disorder with variable presentation and severity. Although considered a skin disease, rosacea may evolve the eyes in 58-72% of the patients, causing eyelid and ocular surface inflammation. About one third of the patients develop potentially sight-threatening corneal involvement. Untreated rosacea may cause varying degrees of ocular morbidity. The importance of early diagnosis and adequate treatment cannot be overemphasized. There is not yet a diagnostic test for rosacea. The diagnosis of ocular rosacea relies on observation of clinical features, which can be challenging in up to 90% of patients in whom accompanying roseatic skin changes may be subtle or inexistent. In this review, we describe the pathophysiologic mechanisms proposed in the literature, clinical features, diagnosis and management of ocular rosacea, as well as discuss the need for a diagnostic test for the disease.

  4. Pediatric genetic ocular tumors

    OpenAIRE

    Rouhani, Behnaz; Ramasubramanian, Aparna

    2014-01-01

    Pediatric genetic ocular tumors include malignancies like retinoblastoma and phakomatosis like neurofibromatosis, tuberous sclerosis, von Hippel-Lindau syndrome, and nevoid basal cell carcinoma syndrome. It is important to screen for ocular tumors both for visual prognosis and also for systemic implications. The phakomatosis comprise of multitude of benign tumors that are aysmptomatic but their detection can aid in the diagnosis of the syndrome. Retinoblastoma is the most common malignant int...

  5. Ocular rosacea: a review Rosácea ocular: revisão

    Directory of Open Access Journals (Sweden)

    Ana Carolina Cabreira Vieira

    2012-10-01

    Full Text Available Rosacea is a prevalent chronic cutaneous disorder with variable presentation and severity. Although considered a skin disease, rosacea may evolve the eyes in 58-72% of the patients, causing eyelid and ocular surface inflammation. About one third of the patients develop potentially sight-threatening corneal involvement. Untreated rosacea may cause varying degrees of ocular morbidity. The importance of early diagnosis and adequate treatment cannot be overemphasized. There is not yet a diagnostic test for rosacea. The diagnosis of ocular rosacea relies on observation of clinical features, which can be challenging in up to 90% of patients in whom accompanying roseatic skin changes may be subtle or inexistent. In this review, we describe the pathophysiologic mechanisms proposed in the literature, clinical features, diagnosis and management of ocular rosacea, as well as discuss the need for a diagnostic test for the disease.A rosácea é uma condição cutânea crônica, que possui apresentações clínicas variáveis. Apesar de considerada uma doença dermatológica, os olhos podem ser acometidos em 58-72% dos casos, causando inflamação palpebral e da superfície ocular. Aproximadamente um terço dos pacientes desenvolve acometimento corneano, podendo causar baixa visual significativa. Diagnóstico precoce e tratamento adequado são de extrema importância, devido à significativa morbidade ocular que a doença pode causar. Não há, até o momento, um teste diagnóstico para rosácea. O diagnóstico da rosácea ocular depende da observação das manifestações clínicas, o que pode ser bastante desafiador em até 90% dos pacientes, em que os achados cutâneos são discretos ou inexistentes. Nesta revisão, descrevemos os mecanismos fisiopatológicos propostos na literatura, manifestações clínicas, diagnóstico e tratamento da rosácea ocular, assim como abordamos a necessidade de um teste diagnóstico.

  6. Vestibulo-ocular reflex.

    Science.gov (United States)

    Dieterich, M; Brandt, T

    1995-02-01

    Recent animal and clinical studies on the vestibulo-ocular reflex deal with a number of physiological and clinical aspects from which three were chosen for this review: (1) the torsional vestibulo-ocular reflex and its disorders; (2) the otolith contribution to the vestibulo-ocular reflex; and (3) neurotransmitters, neuropharmacological aspects, and medical treatment. Disorders of the vestibulo-ocular reflex can be classified according to the three major planes of action, yaw plane, pitch plane, and roll plane, which equate with horizontal nystagmus, upbeat or downbeat nystagmus, and torsional nystagmus, respectively. The particular interest in the torsional vestibulo-ocular reflex arises from new methods for measuring ocular torsion, especially the three-dimensional eye-movement recordings with scleral coils. These methods make it possible to do three-dimensional analysis of the differential effects of horizontal and vertical semicircular canal function and their individual disorders of the torsional vestibulo-ocular reflex. Otolith and semicircular canal inputs converge at the level of the vestibular nuclei to subserve static graviceptive and dynamic torsional and pitch function. The elaboration of the particular sensorial weight of the input from either the otoliths or the semicircular canal is currently a challenge for both physiologists and neurologists. Disorders of otolith function, still absent from the diagnostic repertoire of most neurologists, are increasingly being reported. The most promising developments in therapeutic measures may come from research on vestibular neurotransmitters, their agonists and antagonists. A number of pharmacological agents are effective suppressants of pathological eye movements. However, systematic prospective studies are needed.(ABSTRACT TRUNCATED AT 250 WORDS)

  7. Heterogeneity of Disease Classified as Stage III in Wilms Tumor: A Report From the Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP)

    Energy Technology Data Exchange (ETDEWEB)

    Spreafico, Filippo, E-mail: filippo.spreafico@istitutotumori.mi.it [Pediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); Gandola, Lorenza [Department of Radiology/Radiotherapy, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); D' Angelo, Paolo [Pediatric Oncology, Ospedale dei Bambini G. di Cristina, Palermo (Italy); Terenziani, Monica [Pediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); Collini, Paola [Department of Pathology and Laboratory Medicine, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); Bianchi, Maurizio [Pediatric Department, Ospedale Infantile Regina Margherita, Torino (Italy); Provenzi, Massimo [Pediatric Unit, Ospedali Riuniti Bergamo, Bergamo (Italy); Indolfi, Paolo [Pediatric Oncology, Pediatric Department, II University, Napoli (Italy); Pession, Andrea [Pediatric Hematology and Oncology Unit ' Lalla Seragnoli' , Bologna University, Bologna (Italy); Nantron, Marilina [Department of Hematology and Oncology, Istituto G. Gaslini, Genova (Italy); Di Cataldo, Andrea [Pediatric Hematology and Oncology, Catania University, Catania (Italy); Marchiano, Alfonso [Department of Radiology/Radiotherapy, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); Catania, Serena; Fossati Bellani, Franca [Pediatric Unit, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy); Piva, Luigi [Pediatric Surgery Unit, Urology, Fondazione IRCCS Istituto Nazionale Tumori, Milano (Italy)

    2012-01-01

    Purpose: We analyzed whether the prognosis can differ among Wilms tumors (WT) labeled as Stage III according to currently adopted classification systems. Methods and Materials: Patients with nonanaplastic Stage III WT consecutively registered in two Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) trials (CNR-92, TW-2003) were the subjects in the present analysis. The steady mainstay of therapy was primary nephrectomy, followed by three-drug chemotherapy with vincristine, dactinomycin, doxorubicin, and abdominal radiotherapy (RT). Results: Ninety-nine WT patients met the criteria for classification as Stage III according to a revised version of the National Wilms Tumor Study-3 staging system (51 patients in CNR-92, 48 patients in TW-2003). Regional lymph nodes (LN) were not biopsied in 16 patients. After a median follow-up of 66 months, the 4-year disease-free survival (DFS) and overall survival (OS) rates were 85% {+-} 4% and 92% {+-} 3%, respectively, for the whole group. For 38 children with positive LN, the 4-year DFS rate was 73% {+-} 7%, as opposed to 98% {+-} 2% for the 45 children with Stage III WT according to the other criteria but with negative biopsied LN (p = 0.001). The subgroup with the worst prognosis consisted of children more than 2 years old with positive LN (DFS 67% {+-} 8%). A delay between surgery and RT > 30 days had an adverse impact on the abdominal tumor relapse rate. Conclusions: This study provides further evidence that Stage III tumors with LN metastases might be distinguished from WTs meeting the other criteria for classification as Stage III. The worse outcome of the former may warrant a prospective study on the effects of intensified therapy. A subclassification of Stage III tumors is discussed.

  8. Pediatric genetic ocular tumors.

    Science.gov (United States)

    Rouhani, Behnaz; Ramasubramanian, Aparna

    2014-12-01

    Pediatric genetic ocular tumors include malignancies like retinoblastoma and phakomatosis like neurofibromatosis, tuberous sclerosis, von Hippel-Lindau syndrome, and nevoid basal cell carcinoma syndrome. It is important to screen for ocular tumors both for visual prognosis and also for systemic implications. The phakomatosis comprise of multitude of benign tumors that are aysmptomatic but their detection can aid in the diagnosis of the syndrome. Retinoblastoma is the most common malignant intraocular tumor in childhood and with current treatment modalities, the survival is more than 95%. It is transmitted as an autosomal dominant fashion and hence the offsprings of all patients with the germline retinoblastoma need to be screened from birth. This review discusses the various pediatric genetic ocular tumors discussing the clinical manifestation, diagnosis and treatment.

  9. Artefactos en ultrasonido ocular

    Directory of Open Access Journals (Sweden)

    Mariana Mayorquín Ruiz

    2016-07-01

    Full Text Available El ultrasonido ocular es un estudio dependiente del operador. Un buen estudio ecográfico debe tener como base el conocimiento de la anatomía y fisiología normales y de los cambios producidos en diferentes enfermedades, así como los cambios tras una cirugía ocular o trauma. El conocimiento de los fenómenos físicos producidos por el ultrasonido es la base para entender y reconocer la presencia de artefactos en el ultrasonido ocular. Esta revisión tiene como objetivo hacer un recuento de los artefactos que pueden ocasionar confusión al interpretar una imagen ecográfica, así como explicar la base física en la que se basan, reduciendo de esta manera los errores de interpretación y diagnósticos.

  10. Taser penetrating ocular injury.

    Science.gov (United States)

    Ng, Weng; Chehade, Mark

    2005-04-01

    To describe the presentation and treatment of a Taser penetrating ocular injury. Case report. A 50-year-old man with a Taser injury 1.5 cm below the right lower eyelid margin was admitted to the emergency department of a tertiary hospital. The case report describes the ophthalmic assessment, investigation, treatment, and outcome of the Taser barb penetrating ocular injury. The Taser has a fish hook barb that caused a full-thickness wound adequately large for vitreous to escape when the Taser was removed. Consequently, the scleral wound was repaired and cryopexy was performed. The affected eye made a satisfactory recovery, and the visual acuity was 6/9 with a pinhole 1 week after operation. Any Taser injury around the orbits should raise the suspicion of a penetrating ocular injury. In likely cases, removal of the Taser should be performed in an operating theater under general anesthesia.

  11. Feline ocular emergencies.

    Science.gov (United States)

    Giuliano, Elizabeth A

    2005-05-01

    Feline ocular emergencies include any ophthalmic condition that has rapidly developed or is the result of trauma to the eye or periocular structures. Common feline emergencies include proptosis, lid lacerations, corneal ulcers, and foreign bodies. Complete ophthalmic examination including procurement of the minimal ophthalmic database (Schirmer tear test, fluorescein stain, and intraocular pressure measurement) should be obtained whenever possible to ensure that the complete and correct diagnosis is made. Concern for the patient's vision and ocular comfort should guide the practioner's diagnostic and therapeutic plan. This article reviews some of the more common feline ocular emergencies, including conditions affecting the orbit and globe, adnexa, conjunctiva, and cornea. Feline uveitis, glaucoma, and lenticular diseases are covered more thoroughly elsewhere in this issue.

  12. Oculomotricidade e seus fundamentos Ocular motility: foundations

    Directory of Open Access Journals (Sweden)

    Harley E. A. Bicas

    2003-10-01

    Full Text Available Partindo-se de um circuito esquemático relacionando os sistemas sensorial (visual binocular e oculomotor, cujos defeitos em vias aferentes ou eferentes, ou de suas interações, explicam o aparecimento dos estrabismos e suas conseqüências, são examinados os fundamentos e referenciais da movimentação ocular. Apresentam-se os conceitos de eixos e planos, centro de massa e de rotação, definem-se os movimentos monoculares de translação e de rotação e os binoculares de versões e vergências. É também referida a função dos centros de comando para movimentos voluntários e reflexos, a dos núcleos oculomotores e a respectiva inervação aos músculos oculares externos. Numa segunda parte (fisiologia da musculatura ocular extrínseca são comentadas as atividades de contração e relaxamento e a importância da lei de Sherrington. Voltando-se ao conceito de posição primária do olhar e dos referenciais das rotações, menciona-se a diversidade de vários sistemas de medidas. Em seguida, são analisadas as ações musculares rotacionais com bases no plano de ação muscular e na distribuição anatômica dos músculos, levando a resultados em posição primária do olhar e nas outras. Os efeitos de fáscias e membranas intermusculares são também comentados, terminando-se com a concepção moderna sobre as ações musculares (ação simultânea de todos os músculos em quaisquer das posições oculares. Com os condicionantes da lei de Hering, desenvolve-se o conceito de posições diagnósticas (das disfunções oculomotoras, diferentemente do clássico: os músculos são considerados em pares, de acordo às suas ações predominantes ___ horizontais (retos horizontais, verticais (retos verticais ou torcionais (oblíquos. Em cada qual devem ser comparadas as ações em condições diametralmente opostas de fixação ocular e posições do olhar (por exemplo, supradextroversão na fixação com o olho direito e infralevoversão na fixa

  13. What Is an Ocular Migraine?

    Science.gov (United States)

    ... When to seek help What is an ocular migraine? Is it a sign of something serious? Answers ... and retinal migraine, which could signal something serious. Migraine aura affecting your vision Ocular migraine sometimes describes ...

  14. Achados oculares em crianças de zero a seis anos de idade, residentes na cidade de São Caetano do Sul, SP Ocular findings in children between 0 and 6 years of age, residing in the city of São Caetano do Sul, SP

    Directory of Open Access Journals (Sweden)

    Sandra Maria Canelas Beer

    2003-12-01

    Full Text Available OBJETIVO: Determinar a prevalência de erros refrativos, estrabismo, ambliopia e anisometropia nas crianças pertencentes à população em estudo, utilizando dois métodos de rastreamento (triagem na escola e triagem durante o dia da vacinação contra a poliomielite. MÉTODOS: Foram examinadas 2.640 crianças, residentes da cidade de São Caetano do Sul, entre zero e seis anos de idade, divididas em duas amostras (A e B. A amostra A consistiu de 476 crianças que foram examinadas por dez oftalmologistas e onze técnicos oftálmicos, durante o Dia Nacional de Vacinação (20 de junho de 1998 contra a Poliomielite. A amostra B consistiu de 2.164 crianças que freqüentavam escolas municipais, entre quatro e seis anos de idade e foram examinadas por dois oftalmologistas durante o ano de 1998. RESULTADOS: Na amostra A, a prevalência de estrabismo foi de 3,36% e de anisometropia foi de 1,26%. O principal tipo de erro refrativo encontrado foi a hipermetropia PURPOSE: To establish the prevalence of refractive errors, strabismus, amblyopia and anisometropia, among children in a population, using two methods of screening (at school and at the National Polio Vaccination Day. METHODS: We examined 2,640 children, between 0 and 6 years of age. The children, residents of the city São Caetano do Sul, were divided into two groups (A and B. Group A: 476 children, with an age range of a few months to 6 years, had their eyes examined by 10 ophthalmologists and 11 ophthalmology technicians, during the National Polio Vaccination Day (June 20,1998. Group B: 2,164 children attending municipal schools (EMEIs and EMIs, between 4 and 6 years of age, who had their eyes examined by two ophthalmologists during the year of 1998. RESULTS: In group A, the prevalence of strabismus was 3.36% and that of anisometropia was 1.26%. The most common type of refractive error was hypermetropia £ 2D and 14.11% required optical prescription. In group B, the prevalence of strabismus

  15. Combat Ocular Problems. Supplement,

    Science.gov (United States)

    1982-04-01

    Brooks Air Force Base, TX: USAF School of Aerospace Medicine, 1978 6. BROWNELL , A.S., and B.E. STUCK. Ocular and skin hazards from C02 laser...acuity following laser radiation. In: Proceedings of the Human Factors Society. 1980. pp 162-166 9. KELLY , D.H. Photopic contrast sensitivity without

  16. Ocular Adnexal Follicular Lymphoma

    DEFF Research Database (Denmark)

    Rasmussen, Peter K; Coupland, Sarah E; Finger, Paul T

    2014-01-01

    IMPORTANCE The clinical features of the follicular subtype of ocular adnexal lymphoma (OAL) have not been previously evaluated in a large cohort. OBJECTIVE To characterize the clinical features of follicular OAL. DESIGN, SETTING, AND PARTICIPANTS We performed a retrospective multicenter study tha...

  17. Ocular straylight in albinism

    NARCIS (Netherlands)

    Kruijt, Bastiaan; Franssen, Luuk; Prick, Liesbeth J. J. M.; van Vliet, Johannes M. J.; van den Berg, Thomas J. T. P.

    2011-01-01

    Albinism is an inherited disorder that affects the melanin biosynthesis pathway, which results in reduced or absent pigment formation. This may lead to increased light transmission through the iris and more reflected light from the fundus. Both these effects contribute to the occurrence of ocular

  18. Ocular manifestations of leptospirosis

    Directory of Open Access Journals (Sweden)

    Rathinam S

    2005-01-01

    Full Text Available Leptospiral uveitis is a common entity in tropical countries. Ocular manifestations are noted in the second phase of illness, but these remain under-diagnosed mainly because of the prolonged symptom-free period that separates the systemic manifestations from detection of ocular manifestations.Varying ophthalmic presentations and the intrinsic nature of different types of uveitis to mimic one another also challenge the accuracy of the diagnosis. Of the individual ocular signs, the combination of acute, non-granulomatous, panuveitis, hypopyon, vasculitis, optic disc edema, membranous vitreous opacities and absence of choroiditis or retinitis have high predictive value for the clinical diagnosis of leptospiral uveitis. Geographic location of the patient, occupation, socio-economic status, risk factors related to exposure, past history of fever or jaundice also aid in diagnosis.Steroids are the mainstay of treatment for leptospiral uveitis. Depending upon the severity and anatomical location of inflammatory lesion, topical, peri-ocular and/or systemic steroids are given. The prognosis is generally good, even when the inflammation is severe.

  19. Goldenhar syndrome: ocular features.

    Science.gov (United States)

    Bhallil, S; Benatiya, I; El Abdouni, O; Mahjoubi, B; Hicham, T

    2010-01-01

    Goldenhar syndrome is a rare congenital anomaly which consists of a triad of an ocular dermoid cyst, preauricular skin tags and vertebral dysplasia. We report two cases of Goldenhar syndrome, diagnosed in a 4-year-old girl and in a 20-year-old young adult. The dermoid cyst is a benign tumour with serious ophthalmologic complications.

  20. Atenção à saúde ocular de crianças com alterações no desenvolvimento em serviços de intervenção precoce: barreiras e facilitadores

    Directory of Open Access Journals (Sweden)

    Gabriela Cordeiro Corrêa do Nascimento

    Full Text Available RESUMO Objetivo: Identificar fatores que influenciam na detecção precoce de deficiência visual e o início da intervenção precoce de crianças com alterações no desenvolvimento. Métodos: O estudo constituiu-se de levantamento, exploratório e descritivo, que contou com a aplicação de questionários com representantes institucionais, profissionais da equipe dos serviços de intervenção precoce e mães ou cuidadores das crianças atendidas. Os dados receberam tratamento estatístico através dos softwares Sistema de Análise Estatística SAS 9.3, Wolfram Mathematica e Microsoft Excel.A amostra constituiu-se de 434 sujeitos (19 representantes institucionais, 142 profissionais dos serviços e 273 mães/cuidadores das crianças atendidas. Resultados: A análise dos resultados revelou valores estatísticos de p-valor=0,0119 para a realização do teste do olhinho no que se refere ao início da intervenção precoce. A mãe recebe orientação quanto ao desenvolvimento da visão que obteve valores de p-valor=0,0106 para início da intervenção oportuna e valores de p-valor=0,0061 para primeira consulta ao oftalmologista. Conclusão: Realizar o teste do olhinho constituiu-se fator facilitador para o início da intervenção precoce e ter uma deficiência exclusivamente visual e frequentar instituição privada como barreira.A entrada tardia em serviço de intervenção precoce afeta negativamente a idade da primeira consulta oftalmológica. A mãe recebe orientação quanto ao desenvolvimento da visão que revelou-se fator facilitador para a primeira consulta ao oftalmologista e para início da intervenção oportuna. O campo da saúde ocular constitui-se demanda da saúde pública e requer ações e programas educativos direcionados aos familiares, profissionais e gestores institucionais.

  1. Ocular allergy and keratoconus

    Directory of Open Access Journals (Sweden)

    Namrata Sharma

    2013-01-01

    Full Text Available Keratoconus is the most common corneal ectatic disorder, the cause of which is largely unknown. Many factors have been implicated, and the ocular allergy is being one of them. The commonly proposed pathogenesis includes the release of inflammatory mediators due to eye rubbing which may alter the corneal collagen and lead to corneal ectasias. The onset of keratoconus is often early in cases associated with allergy and routine corneal topography may detect subtle forms of keratoconus. These cases may require early keratoplasty and are at an increased risk of having acute corneal hydrops. Surgical outcomes are similar to primary keratoconus cases. However, post-operative epithelial breakdown may be a problem in these cases. Control of allergy and eye rubbing is the best measure to prevent corneal ectasias in cases of ocular allergy.

  2. Sclerodermatomyositis, ocular manifestations.

    Science.gov (United States)

    Pedroza-Seres, M; Serna-Ojeda, J C; Flores-Suárez, L F

    2017-07-01

    Sclerodermatomyositis is an overlap syndrome of myositis and scleroderma, with dermatological, muscular and joint involvement, but may also present with ocular manifestations. A 57 year-old woman presented with ophthalmological manifestations, including scleral thinning 360°, and the presence of cells in the anterior and posterior chamber. Oriented physical examination and laboratory studies led to the diagnosis, with the need for systemic treatment. Sclerodermatomyositis is a rare disease. Its diagnosis needs thorough clinical and laboratory studies, and its management should be multidisciplinary when inflammatory ocular manifestations may be present. Copyright © 2016 Sociedad Española de Oftalmología. Publicado por Elsevier España, S.L.U. All rights reserved.

  3. Cardiopulmonary effects and eyeball centralization with low-dose atracurium in spontaneously breathing, anesthetized dogs Avaliação cardiopulmonar e da centralização do globo ocular em cães com baixas doses de atracúrio mantidos em anestesia inalatória sob ventilação espontânea

    Directory of Open Access Journals (Sweden)

    Adriano Bonfim Carregaro

    2010-07-01

    Full Text Available The objective was to determine the cardiopulmonary effects and eyeball centralization time obtained with 15 or 30µg kg-1 of atracurium in anesthetized dogs under spontaneous breathing. Eighteen healthy adult mixed-breed dogs were used, which received 0.1mg kg-1 acepromazine and 0.5mg kg-1 morphine IM, followed by 4mg kg-1 propofol IV and maintained on isoflurane anesthesia with spontaneous breathing. Animals received 1mL 0.9% NaCl IV (CG, 15µg kg-1 (G15 or 30µg kg-1 (G30 of atracurium IV. Eyeball centralization time was measured; heart rate (HR, systolic (SAP, mean (MAP and diastolic (DAP arterial pressures, respiratory rate (RR, tidal volume (Vt and minute volume (Vm were determined every 5min, and pH, arterial CO2 pressure (PaCO2 , arterial O2 pressure (PaO2 , hemoglobin oxygen saturation (SaO2 , bicarbonate (HCO3- and base excess (BE every 15min until 60min. Both doses of atracurium produced a similar period of eyeball centralization. Vt in groups treated with atracurium was lower than in CG up to 15min. Vm in G15 differed from CG up to 10min and in G30 up to 25min. No differences were observed for cardiovascular parameters, RR, SaO2, PaO2, HCO3- and BE. pH decreased in CG between 30 and 60min and in G15 and G30 at 15min. G30 differed from CG between 15 and 30min. PaCO2 in GC differed from baseline between 30 and 60min and in G15 differed at 15min. Atracurium at the dose of 15µg kg-1 is adequate for short corneal procedures in inhalant-anesthetized dogs under spontaneous breathing.Objetivou-se determinar os efeitos cardiopulmonares e o tempo de centralização do globo ocular obtidos com 15 ou 30µg kg-1 de atracúrio em cães anestesiados sob ventilação espontânea. Dezoito cães adultos foram pré-medicados com 0,1mg kg-1 de acepromazina e 0,5mg kg-1 de morfina IM, anestesiados com 4mg kg-1 de propofol IV e mantidos sob anestesia inalatória com isofluorano em ventilação espontânea. Os animais receberam 1mL de NaCl 0,9% IV (GC, 15

  4. Efeito terapêutico da aplicação intra-ocular de ozônio em modelo experimental de endoftalmite por Staphylococcus epidermidis em coelhos Therapeutic effect of intraocular application of ozone in experimental Staphylococcus epidermidis endophthalmitis

    Directory of Open Access Journals (Sweden)

    Jonathan Clive Lake

    2004-08-01

    Full Text Available OBJETIVO: Avaliar a ação antiinflamatória e antimicrobiana da injeção intravítrea de ozônio diluído em solução salina balanceada (BSS em modelo experimental de endoftalmite por Staphylococcus epidermidis. MÉTODOS: Dezessete coelhos da raça Nova Zelândia receberam inoculação no olho direito de 0,1 ml de uma solução de 10(5 bactérias (S. epidermidis por ml para indução de endoftalmite. Sete coelhos receberam injeção intravítrea de 0,1ml de BSS como controle e os outros dez coelhos receberam injeção intravítrea de 0,1ml de BSS com ozônio diluído a 2 ppm. Os dados foram quantificados de acordo com parâmetros clínicos e histopatológicos e computados numericamente para cada coelho após 24 horas de evolução. As médias e os desvios-padrão (DP foram calculados e comparados por meio de teste t com duas amostras. RESULTADOS: A média da quantificação clínica dos olhos dos coelhos do grupo controle foi de 11,14 com DP de 1,04. A média clínica dos olhos tratados com ozônio foi de 4,90 com DP de 1,29. A média dos olhos tratados com ozônio foi significativamente menor do que os não tratados (PPURPOSE: To evaluate the anti-inflammatory and antimicrobial effect of intraocular ozone diluted in BSS on experimental Staphylococcus epidermidis endophthalmitis. METHODS: We injected 0.1ml of S. epidermidis colonies (10(5 colonies/ml to produce experimental endophthalmitis in the right eyes of 17 New Zealand rabbits. Seven rabbits were assigned to a control group and received an intravitreal injection of 0.1ml BSS. Ten rabbits were treated with intravitreal injection of 0.1ml BSS-diluted ozone (2 ppm. Data were distributed according to clinical and histological findings after 24 hours, each rabbit receiving a score. Mean scores and standard deviations were compared using the two-sample t test. RESULTS: Mean clinical score for the control group was 11.14 ± 1.04. Mean clinical score for the treated group was 4.90 ± 1

  5. Ocular Response Analyzer

    OpenAIRE

    Kaushik, Sushmita; Pandav, Surinder Singh

    2012-01-01

    Until recently, corneal biomechanical properties could not be measured in vivo. The ocular response analyzer is a new, noninvasive device that analyses corneal biomechanical properties simply and rapidly. The ORA allows cornea compensated IOP measurements and can estimate corneal hysteresis (CH) and corneal resistance factor (CRF). It is designed to improve the accuracy of IOP measurement by using corneal biomechanical data to calculate a biomechanically adjusted estimate of intraocular press...

  6. Microsporidia: Emerging Ocular Pathogens

    Directory of Open Access Journals (Sweden)

    Joseph J

    2005-01-01

    Full Text Available Microsporidia are eukaryotic, spore forming obligate intracellular parasites, first recognized over 100 years ago. Microsporidia are becoming increasingly recognized as infectious pathogens causing intestinal, ocular, sinus, pulmonary, muscular and renal diseases, in both immunocompetent and immunosuppressed patients. Ocular microsporidiosis, though uncommon, could be isolated or part of systemic infections. It occurs mainly in two forms: keratoconjunctivitis form, mostly seen in immunocompromised individuals; stromal keratitis form seen in immunocomptetant individuals. Recent reports indicate increasing number of cases of ocular microsporidiosis in immunocompetent individuals. The ocular cases present as superficial keratitis in AIDS patients, and these differ in presentation and clinical course from the cases seen in immunocompetent individuals which mainly appear to be as deep stromal keratitis. For most patients with infectious diseases, microbiological isolation and identification techniques offer the most rapid and specific determination of the etiologic agent, however this does not hold true for microsporidia, which are obligate intracellular parasites requiring cell culture systems for growth. Therefore, the diagnosis of microsporidiosis currently depends on morphological demonstration of the organisms themselves, either in scrapings or tissues. Although the diagnosis of microsporidiosis and identification of microsporidia by light microscopy have greatly improved during the last few years, species differentiation by these techniques is usually impossible and electron microscopy may be necessary. Immuno fluorescent-staining techniques have been developed for species differentiation of microsporidia, but the antibodies used in these procedures are available only at research laboratories at present. During the last 10 years, molecular techniques have been developed for the detection and species differentiation of microsporidia.

  7. Human ocular anatomy.

    Science.gov (United States)

    Kels, Barry D; Grzybowski, Andrzej; Grant-Kels, Jane M

    2015-01-01

    We review the normal anatomy of the human globe, eyelids, and lacrimal system. This contribution explores both the form and function of numerous anatomic features of the human ocular system, which are vital to a comprehensive understanding of the pathophysiology of many oculocutaneous diseases. The review concludes with a reference glossary of selective ophthalmologic terms that are relevant to a thorough understanding of many oculocutaneous disease processes. Copyright © 2015 Elsevier Inc. All rights reserved.

  8. Bilateral ocular osseous choristomas

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Jeung Hee; Yoon, Dae Young; Choi, Chul Soon; Yoon, Eun Joo; Park, Sang Joon; Seo, Young Lan [Hallym University, Department of Radiology, Kangdong Sacred Heart Hospital, Seoul (Korea); Kim, Byoung Jin [Hallym University, Department of Ophthalmology, Kangdong Sacred Heart Hospital, Seoul (Korea)

    2005-11-01

    Choristoma is a benign tumour defined as normal tissue in an ectopic location. Osseous choristoma, one subtype of this entity, occurring within the orbit has rarely been reported in the world literature. We report a 6-year-old girl with bilateral ocular osseous choristomas who presented with palpable nodules protruding from both upper lids. The radiological and clinical findings are described and previous reports are reviewed. (orig.)

  9. Immunohistochemistry in ocular carcinomas.

    Science.gov (United States)

    Sramek, Brett; Lisle, Allison; Loy, Timothy

    2008-07-01

    The distinction between ocular sebaceous carcinoma, poorly differentiated ocular squamous cell carcinoma and ocular basal cell carcinoma can be challenging. An appropriate immunohistochemical panel may help to differentiate these lesions. To determine the distribution and use of several immunostains in these specimens, formalin-fixed, paraffin-embedded tissue from several of each was studied using an immunohistochemical technique. Positive staining for cytokeratin (CK)7 was seen in 100% of sebaceous carcinomas, 77.8% of basal cell carcinomas and 67.7% of squamous cell carcinomas. One hundred percent of sebaceous and basal cell carcinomas were positive for cytokeratin CAM 5.2, while only 83.3% of squamous cell carcinomas were positive. Using epithelial membrane antigen (EMA), 100% of squamous cell carcinomas and 80% of sebaceous carcinomas were positive, while basal cell carcinomas were uniformly negative. One hundred percent of basal cell carcinomas and 80% of sebaceous carcinomas were positive for Ber-EP4, while all squamous cell carcinomas were negative. Finally, 77.8%, 20% and 16.7% of basal cell carcinomas, sebaceous carcinomas and squamous cell carcinomas showed immunoreactivity for the androgen receptor. An EMA positive, Ber-EP4 positive immunophenotype supports sebaceous carcinoma, EMA positive, Ber-EP4 negative result supports squamous cell carcinoma and an EMA negative, Ber-EP4 positive result supports basal cell carcinoma.

  10. Ocular injury in hurling.

    LENUS (Irish Health Repository)

    Flynn, T H

    2012-02-03

    OBJECTIVES: To describe the clinical characteristics of ocular injuries sustained in hurling in the south of Ireland and to investigate reasons for non-use of protective headgear and eye wear. METHODS: Retrospective review of the case notes of 310 patients who attended Cork University Hospital or Waterford Regional Hospital between 1 January 1994 and 31 December 2002 with ocular injuries sustained during a hurling match. A confidential questionnaire on reasons for non-use of protective headgear and eye wear was completed by 130 players. RESULTS: Hurling related eye injuries occurred most commonly in young men. Fifty two patients (17%) required hospital admission, with hyphaema accounting for 71% of admissions. Ten injuries required intraocular surgical INTERVENTION: retinal detachment repair (5); macular hole surgery (1); repair of partial thickness corneal laceration (1); repair of globe perforation (1); enucleation (1); trabeculectomy for post-traumatic glaucoma (1). Fourteen eyes (4.5%) had a final best corrected visual acuity (BCVA) of <6\\/12 and six (2%) had BCVA <3\\/60. In the survey, 63 players (48.5%) reported wearing no protective facemask while playing hurling. Impairment of vision was the most common reason cited for non-use. CONCLUSIONS: Hurling related injury is a significant, and preventable, cause of ocular morbidity in young men in Ireland. The routine use of appropriate protective headgear and faceguards would result in a dramatic reduction in the incidence and severity of these injuries, and should be mandatory.

  11. Ocular Paintball Injuries.

    Science.gov (United States)

    Nemet, Arie Y; Asalee, Leena; Lang, Yaron; Briscoe, Daniel; Assia, Ehud I

    2016-01-01

    Background: One of the most alarming ocular injury trends in recent years has been the proliferation of paintball guns and the proportional increase in the number of ocular eye injuries caused by paintballs. To describe five cases of paintball eye injuries that resulted in loss of functional vision in four of them. We conducted a retrospective review of the clinical course in five patients with paintball eye injuries treated in the ophthalmology departments of two medical centers. Five young males were evaluated for paintball injuries caused by blunt trauma. There was one case of full-thickness laceration (globe rupture). Four patients required one to five surgical interventions: three of these involved the removal of traumatic cataract including two eyes with significant zonular dehiscence treated by lens capsule conservation using anchoring devices, one retinal surgery and two glaucoma filtration surgeries. However, final visual outcome was not favorable due to irreversible retinal damage. Paintball trauma often results in significant ocular injury and loss of functional vision despite successful surgical intervention. Most injuries occur in under-supervised settings and are easily preventable. Improved safety measures, strict regulation enforcement and appropriate public education could prevent such serious damage.

  12. Avaliação comparativa do efeito dos colírios de apraclonidina e latanoprost na profilaxia da hipertensão ocular pós capsulotomia com YAG Laser em pacientes não glaucomatosos Profilatic use of apraclonidine and latanoprost to prevent intraocular pressure elevation following Nd:YAG laser posterior capsulotomy

    Directory of Open Access Journals (Sweden)

    Juliane de Freitas S. Paranhos

    1999-10-01

    Full Text Available Objetivo: Comparar a eficácia do latanoprost 0,005% e da apraclonidina 1% na prevenção da hipertensão ocular pós-capsulotomia posterior com YAG laser, em pacientes não- glaucomatosos. Método: Trinta e seis pacientes (36 olhos incluídos foram divididos em três grupos que usaram latanoprost 0,005%, apraclonidina 1% ou placebo. Foram realizadas medidas da pressão ocular antes da instilação de qualquer colírio, 30 minutos após a dilatação, 1 hora e 4 horas após o YAG laser. Resultados: Não houve diferença significativa entre os 3 grupos em relação à idade, pressão ocular inicial e pós-dilatação, assim como em quantidade de energia utilizada. Na primeira hora, tanto para a diferença absoluta quanto para o percentual de alteração da pressão intra-ocular, o grupo da apraclonidina apresentou redução estatisticamente maior em relação ao grupo controle (p 0,05. Na 4a. hora não houve diferença significativa entre os grupos (p > 0,05. As medidas de pressão nos 4 intervalos não apresentaram variação estatisticamente significativa (p > 0,05. A quantidade de energia utilizada não mostrou correlação significativa com o aumento da Po (p > 0,05. Conclusão: A apraclonidina 1% apresentou maior eficácia na profilaxia da hipertensão após capsulotomia posterior com YAG laser quando comparada com latanoprost 0,005%.Purpose: To compare the efficacy of 0.005% latanoprost and 1% apraclonidine in the prevention of an increase of intraocular pressure (IOP after Nd: YAG laser capsulotomy in nonglaucomatous patients. Methods: Thirty-six patients were included and divided in to three groups. Patients received 0.005% latanoprost. 1% apraclonidine or placebo. Four measurements of IOP were made: before instillation of any drug, 30 minutes after cycloplegia, 1 hour and 4 hours after laser. Results: No significant difference was found between the three groups regarding age, initial intraocular pressure, pressure 30 minutes after

  13. Iontoforese no transporte ocular de drogas Iontophoresis for ocular drug delivery

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    Sílvia Ligório Fialho

    2004-10-01

    Full Text Available O método mais comum de administração de drogas no olho é por meio de colírios. Entretanto, por este método, não é possível atingir a concentração terapêutica nos fluidos e tecidos posteriores do olho. A administração sistêmica apresenta reduzido acesso ao segmento posterior do olho devido à presença das barreiras oculares. Injeções subconjuntivais e retrobulbares não são capazes de proporcionar níveis adequados da droga, e a injeção intravítrea é método invasivo, inconveniente e que apre-senta riscos de perfuração do bulbo ocular ou descolamento da retina. A iontoforese, no entanto, apresenta-se como alternativa para o transporte de doses terapêuticas de drogas para o segmento posterior do olho. A iontoforese é uma técnica que consiste na administração de drogas para o organismo através dos tecidos, utilizando um campo elétrico. O eletrodo ativo, que se encontra em contato com a droga, é colocado no local a ser tratado, e um segundo eletrodo, com a finalidade de fechar o circuito elétrico, é colocado em outro local do organismo. O campo elétrico facilita o transporte da droga, que deve se encontrar, preferencialmente, na forma ionizada. A iontoforese pode ser considerada como um método seguro e não invasivo de transporte de drogas para locais específicos do olho. Aplicada experimentalmente para o tratamento de doenças oculares, esta técnica tem evoluído muito nos últimos anos e, atualmente, testes clínicos de fase III encontram-se em andamento.The most traditional method of ocular drug delivery is through the use of eyedrops. However, by this method, the therapeutic concentration in deep ocular fluids and tissues can not be efficiently reached. Systemic administration presents poor access to the posterior segment of the eye due to ocular barriers. Subconjuntival and retrobulbar injections are not able to produce adequate levels of the drug, and intravitreal injection is an invasive and problematic

  14. Ocular defects in cerebral palsy

    OpenAIRE

    Katoch Sabita; Devi Anjana; Kulkarni Prajakta

    2007-01-01

    There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP) patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  15. Ocular defects in cerebral palsy

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    Katoch Sabita

    2007-01-01

    Full Text Available There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  16. Ocular defects in cerebral palsy.

    Science.gov (United States)

    Katoch, Sabita; Devi, Anjana; Kulkarni, Prajakta

    2007-01-01

    There is a high prevalence of ocular defects in children with developmental disabilities. This study evaluated visual disability in a group of 200 cerebral palsy (CP) patients and found that 68% of the children had significant visual morbidity. These findings emphasize the need for an early ocular examination in patients with CP.

  17. Ocular leech infestation

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    Lee YC

    2015-02-01

    Full Text Available Yueh-Chang Lee, Cheng-Jen Chiu Department of Ophthalmology, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan, ROC Abstract: This case report describes a female toddler with manifestations of ocular leech infestation. A 2-year-old girl was brought to our outpatient clinic with a complaint of irritable crying after being taken to a stream in Hualien 1 day previous, where she played in the water. The parents noticed that she rubbed her right eye a lot. Upon examination, the girl had good fix and follow in either eye. Slit-lamp examination showed conjunctival injection with a moving dark black–brown foreign body partly attached in the lower conjunctiva. After applying topical anesthetics, the leech, measuring 1 cm in length, was extracted under a microscope. The patient began using topical antibiotic and corticosteroid agents. By 1 week after extraction, the patient had no obvious symptoms or signs, except for a limited subconjunctival hemorrhage, and no corneal/scleral involvement was observed. Keywords: leech, ocular foreign body, conjunctival reaction, pediatric ophthalmology

  18. Toxicidade ocular causada pelo tamoxifeno: relato de caso Ocular toxicity caused by tamoxifen: case report

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    Eliane Terumi Inada

    2005-08-01

    Full Text Available O objetivo desse trabalho é relatar um caso de toxicidade ocular pelo tamoxifeno. Para isso, aferiu-se a melhor acuidade visual corrigida de ambos os olhos em tabela de Snellen. Foram realizados biomicroscopia do segmento anterior, refração, oftalmoscopia, angiofluoresceinografia e retinografia numa paciente de 63 anos, sexo feminino, cor branca, em uso de tamoxifeno 20 mg/dia há 4 anos, com acuidade visual corrigida de 20/70 e 20/40. A biomicroscopia do segmento anterior apresentava ceratopatia verticilata e catarata nuclear e cortical posterior de 1+/4 em ambos os olhos. À oftalmoscopia, foi verificado alteração do brilho macular de ambos os olhos. E a angiofluoresceinografia mostrou hiperfluorescência na área macular em fase precoce (defeito em janela. Relata-se um caso de ceratopatia e maculopatia causadas pelo tamoxifeno.To report tamoxifen ocular toxicity. The best visual acuity was measured in both eyes with Snellen chart, slit-lamp examination of anterior segment, refraction, dilated fundus examination, fluorescein angiography and retinography in a 63-year-old patient, female, white, using tamoxifen 20 mg/day for 4 years, with 20/70 and 20/40 corrected visual acuity. The anterior segment examination showed corneal linear subepithelial opacity inferior to the visual axis and nuclear and posterior cortical cataract (1+/4 in both eyes. Fundus examination showed alteration of macular color in both eyes. Fluorescein angiography presented hyperfluorescence in the macular area at an early phase (window defect. Report of keratopathy and maculopathy caused by tamoxifen.

  19. Incidência de opacificação de cápsula posterior em pacientes submetidos à facoemulsificação e implante de lentes intra-oculares acrílicas hidrofílicas expansíveis Incidence of posterior capsule opacification in patients submitted to phacoemulsification and expandable acrylic intraocular lens implantation

    Directory of Open Access Journals (Sweden)

    Hilton Arcoverde Gonçalves de Medeiros

    2006-06-01

    Full Text Available OBJETIVO: Avaliar prospectivamente os resultados das lentes intra-oculares de polímeros expansíveis implantadas em pacientes submetidos à facoemulsificação, quanto à incidência de opacificação de cápsula posterior, levando em consideração a biocompatibilidade das lentes expansíveis. MÉTODOS: O grupo de estudo foi composto por 830 pacientes, 1.200 olhos, que foram submetidos a facoemulsificação, utilizando a mesma técnica, variando-se apenas o diâmetro da capsulorrexe, pelo mesmo cirurgião, no período de 1998 a 2002, com implante de lente intra-ocular hidrofílica expansível. O acompanhamento médio foi de 2,4 anos, variando de seis meses a quatro anos. RESULTADOS: O número total de opacificação de cápsula posterior foi de 54 casos. CONCLUSÃO: A incidência de opacificação de cápsula posterior encontrada no grupo foi de 4,6%.PURPOSE: To evaluate prospectively the results of expandable acrylic intraocular lenses in patients submitted to phacoemulsification as regard posterior capsule opacification. METHODS: The study group consisted of 830 patients, 1,200 eyes that underwent phacoemulsification from 1998 to 2002, by the same surgeon, using the same technique but with different diameters of capsulorrhexis, with expandable hydrophilic acrylic intraocular lens implantation. The mean follow-up was 2.4 years, ranging from 6 months to 4 years. RESULTS: The total number of posterior capsule opacification was 54 cases. CONCLUSIONS: The incidence of posterior capsule opacification was 4.6% in these patients.

  20. Análise da fórmula SRK/T no cálculo de lente intra-ocular em cães portadores de catarata Analysis of the SRK/T formula for calculation of intra-ocular lens in dogs carrying cataract

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    T.P. Peixoto

    2008-12-01

    Full Text Available Foram utilizados 20 cães de raças e idades variadas, machos e fêmeas, portadores de catarata e não diabéticos, os quais foram submetidos ao exame oftálmico. Posteriormente, realizaram-se mensurações oculares empregando-se um ecobiômetro ultra-sônico (ultra-sonografia modo-A para o cálculo do poder dióptrico da lente intra-ocular por meio da fórmula SRK/T. O comprimento axial médio foi de 19,94±1,12mm. Todos os animais foram submetidos à facoemulsificação extracapsular. A lente calculada foi implantada no transoperatório da cirurgia de catarata, obtendo-se média de 37,33±3,05D. A avaliação pós-cirúrgica do erro refracional aos 60 dias de pós-operatório, pela retinoscopia, com a utilização da esquiascopia, foi de 5,57±1,59D. A fórmula SRK/T não ofereceu bons resultados.Twenty males and females non-diabetic dogs of different breeds and ages underwent ophthalmic examination because they presented catarats. Ocular measurements were performed by echobiometry (A-scan ultrasound for intraocular lens power calculation using the SRK/T formula. The obtained mean axial length was 19.94±1.12mm. All animals were submitted to extracapsular phacoemulsification; the mean intraocular lens power implanted was 37.33±3.05. At 60 days postoperative, the refractional error assessed via retinoscopy was 5.57±1.59 D. The SRK/T formula did not offer good results.

  1. Estudo dos achados oculares na síndrome de Stevens-Johnson em pacientes de centro de referência de atendimento terciário Study of the ocular findings in Stevens-Johnson syndrome patients from a tertiary ophthalmologic center

    OpenAIRE

    Marciel Dourado Franca; Jane Palma Galrão Lima; Denise de Freitas; Marcelo Cunha; José Álvaro Pereira Gomes

    2009-01-01

    OBJETIVO: Avaliar a epidemiologia, os possíveis fatores desencadeantes, complicações encontradas e as variedades de tratamentos administrados a um grupo de pacientes com complicações oculares secundárias à síndrome de Stevens-Johnson. MÉTODOS: Realizado estudo prospectivo, série de casos com 22 pacientes portadores de síndrome de Stevens-Johnson. Os pacientes foram estudados seguindo um protocolo com o objetivo de se buscar uma história detalhada sobre a doença, suas manifestações sistêmicas ...

  2. Inteligências Múltiplas: desenvolvendo potencialidades em classe hospitalar

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    Freitas, Soraia Napoleão

    2005-01-01

    Full Text Available Este artigo refere-se ao Projeto de Pesquisa "Inteligências Múltiplas: Desenvolvendo Potencialidades em Classe Hospitalar" iniciando no ano de 2003 no setor de Hemato-Oncologia do Hospital Universitário de Santa Maria-RS (HUSM. As atividades desempenhadas objetivaram descobrir e desenvolver o potencial dos alunos, utilizando como base teórica o espectro de capacidades propostas por Haward Gardner em sua Teoria das Inteligências Múltiplas. Os resultados obtidos ao final de 10 meses de trabalho apontaram progressos nas esferas física, social, afetiva, pessoal e cognitiva das crianças submetidas ao tratamento do câncer

  3. Corticosteroids for ocular toxoplasmosis

    Science.gov (United States)

    Jasper, Smitha; Vedula, Satyanarayana S; John, Sheeja S; Horo, Saban; Sepah, Yasir J; Nguyen, Quan Dong

    2014-01-01

    Background Ocular infestation with Toxoplasma gondii, a parasite, may result in inflammation in the retina, choroid, and uvea and consequently lead to complications such as glaucoma, cataract, and posterior synechiae. Objectives The objective of this systematic review was to assess the effects of adjunctive use of corticosteroids for ocular toxoplasmosis. Search methods We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2012, Issue 9), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE, (January 1950 to October 2012), EMBASE (January 1980 to October 2012), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to October 2012), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We searched the reference lists of included studies for any additional studies not identified by the electronic searches. We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 11 October 2012. Selection criteria We planned to include randomized and quasi-randomized controlled trials. Eligible trials would have enrolled participants of any age who were immunocompetent and were diagnosed with active ocular toxoplasmosis. Included trials would have compared anti-parasitic therapy plus corticosteroids versus anti-parasitic therapy alone, or different doses or times of initiation of corticosteroids. Data collection and analysis Two authors independently screened titles and abstracts retrieved from the electronic searches. We retrieved full-text articles of studies categorized as ‘unsure’ or ‘include’ after review of the abstracts. Two authors independently reviewed each full-text article. Discrepancies were

  4. Resultados da troca de lente intra-ocular de hidrogel opacificada

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    Salera Cristina Moreira

    2004-01-01

    Full Text Available OBJETIVO: Avaliar os resultados da explantação e substituição das lentes intra-oculares (LIO de hidrogel opacificadas. MÉTODOS: Foram analisados retrospectivamente os prontuários de 12 pacientes (15 olhos submetidos à explantação e substituição das lentes intra-oculares de hidrogel opacificadas. RESULTADOS: A opacificação das lentes intra-oculares de hidrogel causou perdas de linhas de visão em 13 olhos (86,7%. A troca das lentes intra-oculares opacificadas promoveu o ganho de linhas de visão em 11 olhos (73,3%. As complicações peroperatórias ocorreram em três olhos (20% e foram as seguintes: perda de óleo de silicone, ruptura total de zônula com perda do saco capsular e ruptura parcial de zônula. Durante a explantação das lentes intra-oculares foi necessária a realização de incisões relaxantes na borda da capsulorrexe anterior em três olhos (20% e em dois olhos (13,3% os hápticos foram cortados sendo retirada somente a zona óptica das lentes intra-oculares. CONCLUSÃO: A cirurgia para explantação e substituição das lentes intra-oculares opacificadas mostrou-se eficaz naqueles pacientes com perdas de linhas de visão (p > 0,05.

  5. Câncer de mama feminino: aspectos clínicos e patológicos dos casos cadastrados de 2005 a 2008 num serviço público de oncologia de Sergipe Female breast cancer: clinical and pathological aspects of cases registered between 2005 and 2008 at a public oncology service in the Brazilian State of Sergipe

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    Leila Luíza Conceição Gonçalves

    2012-03-01

    Full Text Available OBJETIVOS: conhecer os aspectos clínicos e patológicos dos casos de câncer de mama feminino cadastrados num serviço público de oncologia de Sergipe. MÉTODOS: procurou-se fazer uma associação do estadiamento com as características presentes nos tumores. A coleta de dados foi realizada em 165 prontuários de mulheres cadastradas no período de 2005 a 2008 no ambulatório de oncologia do Hospital Cirurgia, localizado em Aracaju-Sergipe, por meio de formulário de coleta de dados, em 2009. RESULTADOS: identificou-se o carcinoma ductal invasivo como o tipo de neoplasia mamária mais frequente com 80,8% dos casos; 76 (46,1% neoplasias foram diagnosticadas em estádio avançado (IIB, III e IV e a mastectomia prevaleceu como tipo de cirurgia utilizado no tratamento independente do estadiamento. Quanto aos receptores hormonais todos apresentaram associação com o grau do estádio e, ainda, notou-se que a positividade do estrogênio e progesterona é fator de proteção para um pior prognóstico. CONCLUSÃO: é notável que os casos de câncer de mama estudados apresentam maior agressividade biológica, cursando com pior prognóstico, considerando o estádio clínico. Fazem-se necessárias ações de detecção precoce voltadas ao câncer de mama na atenção básica de Sergipe para redução da morbi-mortalidade, melhora da sobrevida e qualidade de vida entre as mulheres acometidas por essa neoplasia.OBJECTIVES: to discover the clinical and pathologic aspects of cases of female breast cancer registered at a public oncology service in Sergipe. METHODS: an attempt was made to associate the stage with the characteristics of the tumors. Data was gathered from 165 medical records taken between 2005 and 2008 at the oncology outpatients clinic of the Hospital Cirurgia, in the city of Aracaju, Sergipe, using a data collection form in 2009. RESULTS: ductal invasive carcinoma was identified as the most frequent kind of neoplasia, accounting for 80.8% of

  6. Ocular Argyrosis Mimicking Conjunctival Melanoma.

    Science.gov (United States)

    Tendler, Irwin; Pulitzer, Melissa P; Roggli, Victor; Abramson, David H; Marr, Brian P

    2017-06-01

    To present a novel case of ocular argyrosis mimicking conjunctival melanoma. A 48-year-old man who is a jewelry manufacturer presented with raised pigmented lesions in the inferior fornices of both eyes. Brown-black colored, follicle-like, masses were observed in both fornices. An incisional biopsy confirmed the presence of silver and the diagnosis of ocular argyrosis. Despite its limited negative health effects, ocular argyrosis should be considered in the differential diagnosis of conjunctival pigmented lesions because of the potential for misidentification of neoplastic growth.

  7. Ocular Blood Flow Autoregulation Mechanisms and Methods

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    Xue Luo

    2015-01-01

    Full Text Available The main function of ocular blood flow is to supply sufficient oxygen and nutrients to the eye. Local blood vessels resistance regulates overall blood distribution to the eye and can vary rapidly over time depending on ocular need. Under normal conditions, the relation between blood flow and perfusion pressure in the eye is autoregulated. Basically, autoregulation is a capacity to maintain a relatively constant level of blood flow in the presence of changes in ocular perfusion pressure and varied metabolic demand. In addition, ocular blood flow dysregulation has been demonstrated as an independent risk factor to many ocular diseases. For instance, ocular perfusion pressure plays key role in the progression of retinopathy such as glaucoma and diabetic retinopathy. In this review, different direct and indirect techniques to measure ocular blood flow and the effect of myogenic and neurogenic mechanisms on ocular blood flow are discussed. Moreover, ocular blood flow regulation in ocular disease will be described.

  8. O câncer de mama no estado do Pará, Brasil, e o papel da Liga Acadêmica de Oncologia na promoção da saúde feminina: um relato de experiência

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    Tiago Galan de França

    2017-12-01

    Full Text Available Introdução: O câncer de mama é um grande agressor da saúde feminina, além de ser o segundo câncer mais incidente nessa população. É uma doença geralmente insidiosa, acometendo mulheres em idade mais avançada. Quando presente em mulheres mais jovens tem pior prognóstico. Assim, diagnóstico e tratamento precoces são essenciais para o bom prognóstico das pacientes. O objetivo deste estudo foi fazer um relato de experiência sobre uma ação de extensão realizada pela Liga Acadêmica de Oncologia do Pará (LAOPA para detecção do câncer de mama em uma população de risco e discutir a importância de ações de extensão no Pará. Relato de experiência: Um mutirão de rastreio do câncer de mama foi realizado no município de Ananindeua, Pará, em outubro de 2015. Uma capacitação para os acadêmicos foi feita por meio de aulas expositivas sobre câncer de mama e um treino prático foi realizado em modelos anatômicos. A ação foi dividida em espaços, alguns dos quais destinavam-se às consultas e outro, a uma palestra com o tema “desmistificando o câncer de mama”. Conclusão: O 5º Mutirão da Mama se mostrou extremamente importante para o contexto da saúde feminina no Pará, pois ofertou atendimento clínico e exames gratuitos a uma população de risco para a neoplasia de mama, tornando-se também um projeto símbolo da LAOPA.

  9. Ocular tropism of respiratory viruses.

    Science.gov (United States)

    Belser, Jessica A; Rota, Paul A; Tumpey, Terrence M

    2013-03-01

    Respiratory viruses (including adenovirus, influenza virus, respiratory syncytial virus, coronavirus, and rhinovirus) cause a broad spectrum of disease in humans, ranging from mild influenza-like symptoms to acute respiratory failure. While species D adenoviruses and subtype H7 influenza viruses are known to possess an ocular tropism, documented human ocular disease has been reported following infection with all principal respiratory viruses. In this review, we describe the anatomical proximity and cellular receptor distribution between ocular and respiratory tissues. All major respiratory viruses and their association with human ocular disease are discussed. Research utilizing in vitro and in vivo models to study the ability of respiratory viruses to use the eye as a portal of entry as well as a primary site of virus replication is highlighted. Identification of shared receptor-binding preferences, host responses, and laboratory modeling protocols among these viruses provides a needed bridge between clinical and laboratory studies of virus tropism.

  10. The Ocular Surface Chemical Burns

    OpenAIRE

    Medi Eslani; Alireza Baradaran-Rafii; Asadolah Movahedan; Djalilian, Ali R.

    2014-01-01

    Ocular chemical burns are common and serious ocular emergencies that require immediate and intensive evaluation and care. The victims of such incidents are usually young, and therefore loss of vision and disfigurement could dramatically affect their lives. The clinical course can be divided into immediate, acute, early, and late reparative phases. The degree of limbal, corneal, and conjunctival involvement at the time of injury is critically associated with prognosis. The treatment starts wit...

  11. Trauma ocular y politrauma Ocular trauma and multitrauma

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    Dunia Cruz Izquierdo

    2012-01-01

    Full Text Available Se realizó una revisión sobre el trauma ocular y su manejo en pacientes politraumatizados. Entre las causas más frecuentes de trauma ocular se encuentran los accidentes domésticos, laborales, juegos, actividades recreativas y deportivas. Involucran en un alto por ciento a niños y jóvenes, y predomina el sexo masculino en casi todos los trabajos revisados. No solo en Cuba sino en el mundo, el trauma ocular es fuente importante de ceguera unilateral o bilateral. Se presenta un breve compendio de los términos y definiciones actuales que son utilizados para el manejo del trauma ocular, su clasificación y la ventaja que ofrece aplicar el Puntaje del Trauma Ocular, OTS (Ocular Trauma Score, para el pronóstico de la agudeza visual final de acuerdo a los hallazgos clínicos encontrados en la evaluación inicial. Se hace referencia a los pacientes con politrauma y los aspectos a tener en cuenta por el oftalmólogo para tomar conducta cuando estos presentan heridas penetrantes o perforantes y tienen compromiso vital. En estos casos se hace necesaria la colaboración urgente de múltiples especialistas para primero mantener al paciente con vida y luego disminuir las complicaciones que repercuten en su pronóstico visual.A review was made on the ocular trauma and its management in multitrauma patients. The most common causes comprise domestic and occupational accidents, games, recreational and sport activities. It involves more frequently a high percentage of young people, with male prevalence in almost all the reviewed papers. Ocular trauma is an important source of unilateral or bilateral blindness not only in Cuba but worldwide as well. A brief summary of the current terms and definitions used to manage ocular trauma, their classification and the advantage of the Ocular Trauma Score (OTS to know the possible final visual acuity, according to the clinical findings at the emergency room, were presented. Reference was also made to the multitrauma

  12. Programa Embu Enxergando Melhor: uma proposta de atenção integral à saúde ocular em pré-escolares Embu Seeing Better: a complete eye health program proposal for preschool children

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    Maria Cecília S. Lapa

    2008-06-01

    Full Text Available OBJETIVO: A visão desempenha um papel preponderante no desenvolvimento global da criança. A detecção e o tratamento precoce de problemas visuais são fundamentais para impedir a instalação de seqüelas sensório-motoras irreversíveis. Este estudo visou descrever um programa de atenção integral à saúde ocular de crianças, constituído por ações educativas, de prevenção, de assistência e de reabilitação. MÉTODOS: Estudo descritivo transversal, no qual se utilizaram dados do treinamento dos professores, da triagem visual realizada na escola e do exame oftalmológico e ortóptico de 23.374 crianças, de cinco a sete anos de idade, matriculadas na rede municipal de educação infantil do município do Embu, no período de 1994 a 2002. RESULTADOS: Foram capacitados 600 professores e testados 22.118 (95% pré-escolares. Destes, 4.553 (21% precisavam de exame oftalmológico e, deles, 3.016 (66% compareceram à consulta. Dos examinados, 1.389 (46% receberam prescrição óptica, 477 (16%, foram encaminhadas para tratamento ortóptico e 1.601 (53% receberam alta. CONCLUSÕES: A triagem visual é uma prática eficiente para promover a saúde ocular de pré-escolares, na qual o professor é o elemento chave. Para o êxito destas ações, é fundamental estruturar práticas educativas e de promoção da saúde ocular destinadas às crianças, às famílias e à sociedade.OBJECTIVE: Early detection and prompt treatment of ocular disorders in children are important to avoid lifelong visual impairment. This study aimed to describe a comprehensive eye health care program for preschool children. METHODS: A descriptive cross-sectional study was carried out focusing eye health conditions of 23,374 children, between five and seven years old, of the public preschool system of Embu, a municipality of Sao Paulo, Brazil, from 1994 to 2002. Data were obtained from preschool vision screening programs performed by teachers and from ocular assessments of

  13. Ocular allergy latin american consensus

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    Myrna Serapião dos Santos

    2011-12-01

    Full Text Available PURPOSE: To establish current definition, classification and staging, and to develop diagnosis and treatment recommendations for ocular allergy, by using Delphi approach. METHODS: Ten Latin American experts on ocular allergy participated in a 4-round Delphi panel approach. Four surveys were constructed and answered by panelists. A two-thirds majority was defined as consensus. Definition, classification, staging and diagnosis and treatment recommendations were the main outcomes. RESULTS: "Ocular allergy" was proposed as the general term to describe ocular allergic diseases. Consensus regarding classification was not reached. Signs and symptoms were considered extremely important for the diagnosis. It was consensus that a staging system should be proposed based on the disease severity. Environmental control, avoidance of allergens and the use of artificial tears were recommended as first line treatment. The secondary treatment should include topical anti-histamines, mast cell stabilizers and multi actions drugs. Topical non-steroidal anti-inflammatory and vasoconstrictors were not recommended. Topical corticosteroids were recommended as third line of treatment for the most severe keratoconjunctivitis. Consensus was not reached regarding the use of systemic corticosteroids or immunosuppressant. Surgical approach and unconventional treatments were not recommended as routine. CONCLUSION: The task of creating guidelines for ocular allergies showed to be very complex. Many controversial topics remain unsolved. A larger consensus including experts from different groups around the world may be needed to further improve the current recommendations for several aspects of ocular allergy.

  14. Ocular injuries from paintball pellets.

    Science.gov (United States)

    Thach, A B; Ward, T P; Hollifield, R D; Dugel, P U; Sipperley, J O; Marx, J L; Abrams, D A; Wroblewski, K J; Sonkin, P L; Birdsong, R H; Dunlap, W A

    1999-03-01

    To evaluate the ocular effects of blunt trauma due to injury from a paintball pellet. Noncomparative case series. Thirteen patients who suffered ocular injury from paintballs are described. The patients presented to six different civilian and military emergency departments in tertiary care medical centers. Patients were treated for the ocular injury. Patients were evaluated for initial and final visual acuity. The reason for persistent loss of vision was delineated. There were 12 males and 1 female with an average age of 21 years (range, 12-33 years). Eleven of the 13 had no ocular protection at the time of the ocular injury. On initial examination, nine patients had a hyphema, nine had a vitreous hemorrhage, six had a retinal tear or detachment, three had corneal or corneal-scleral ruptures, and one had traumatic optic neuropathy. The final visual acuity was 20/40 or better in two patients, 20/50 to 20/150 in three patients, and 20/200 or worse in eight patients. Injuries due to paintball pellets can result in severe ocular damage and significant loss of vision. Eyecare professionals should be aware of the risks of this sport and must strongly advise participants to wear adequate protection when involved in this activity.

  15. Lesões oculares por Processionária (Thaumetopoea pityocampa Schiff): relatos de casos

    OpenAIRE

    Francisco Eduardo da Silva Trincão; Ana Filipa Duarte; Ana Aires Magriço; Vítor Santos Maduro; Pedro Alves Albergaria Candelária

    2012-01-01

    A Processionária (Thaumetopoea pityocampa Schiff), vulgarmente conhecida como "lagarta do pinheiro" é um inseto dos pinheiros e cedros, endêmico em meios rurais mas também em meios urbanos. A toxicidade ocular, rara nas últimas décadas pelo desenvolvimento de métodos de erradicação eficazes, é provocada pelos seus pelos e prevê-se mais frequente com o recrudescimento deste inseto. Revemos a epidemiologia da Processionária e as suas lesões oculares a partir de 3 casos clínicos. Caso 1: Doente ...

  16. Alterações oculares em crianças pré-escolares e escolares no município de Duque de Caxias, Rio de Janeiro, Brasil Eye diseases in preschool and school children in the city of Duque de Caxias, Rio de Janeiro, Brazil

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    Abelardo de Souza Couto Júnior

    2010-02-01

    Full Text Available OBJETIVO: Estabelecer a prevalência das alterações oculares, no ano de 2001, em crianças pré-escolares e escolares no município de Duque de Caxias, Rio de Janeiro, Brasil. MÉTODOS: Estudo observacional do tipo transversal, durante campanha de saúde ocular na rede pública de ensino. Crianças com acuidade visual inferior a 0,8 ou com anormalidades foram triadas por voluntários treinados para serem avaliadas por oftalmologistas no Instituto Benjamin Constant. RESULTADOS: Avaliadas 1.800 crianças do total. Destas, 609 (33,83% foram encaminhadas ao IBC. Houve 491 (27,28% do total e 80,62% das crianças triadas que receberam alta por apresentarem visão melhor que 0,8. A prevalência das alterações oculares foi de 3,35%. (ambliopia teve prevalência de 2,00%, estrabismo teve 0,33% e outras causas 1,02%.. Houve 93 crianças (5,17% do total e 15,27% das crianças triadas com ametropias que necessitaram de correção através de óculos. CONCLUSÃO: Demonstrou-se a prevalência das principais alterações oftalmológicas infantis no município de Duque de Caxias e ressaltou-se a necessidade de campanhas para bom êxito no desenvolvimento da acuidade visual das crianças.PURPOSE: To establish the prevalence of the ametropias and eye diseases, in the year 2001, within a preschool and school children in the city of Duque de Caxias, Rio de Janeiro, Brazil. METHODS: Transversal observational study during an ocular health campaign in public education schools. The children that have shown visual acuity lower than 0.8 or other abnormally were referred by trained volunteers to evaluation by ophthalmologists from the Benjamin Constant Institute. RESULTS: From the 1.800 children who were examined, 609 (33.83% were referred to the ophthalmologic examination. There were 491 children (27.28% from total and 80.62% from referred that were dismissed for presenting visual acuity better than 0.8. The Eye diseases prevalence was 3.35% (amblyopia was 2

  17. Comportamento da pressão intra-ocular segundo os efeitos cardiorrespiratórios e hemodinâmicos induzidos pela anestesia com desflurano, em cães submetidos à hipovolemia experimental Behavior of intraocular pressure according to cardiorespiratory and hemodynamic effects induced by desflurane in dogs subjected to experimental hypovolemia

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    Ivia Carmem Talieri

    2005-08-01

    Full Text Available OBJETIVOS: Observar o comportamento da pressão intra-ocular, segundo os efeitos cardiorrespiratórios e hemodinâmicos induzidos pela anestesia geral com desflurano, em cães submetidos à hipovolemia experimental. MÉTODOS: Foram utilizados 18 cães, machos e fêmeas, com peso entre 10 e 15 kg. A hipovolemia foi realizada retirando-se 40 ml de sangue/kg de peso. A seguir, a anestesia foi induzida com desflurano através de máscara facial, até que a intubação orotraqueal fosse permitida. A pressão intra-ocular foi medida por tonometria de aplanação. Valores para freqüência cardíaca, débito cardíaco, pressão arterial média, pressão venosa central e pressão parcial de CO2 ao final da expiração e freqüência respiratória foram mensurados. Os parâmetros da avaliação foram registrados após a instrumentalização e antes de qualquer outro procedimento (T0, quinze minutos depois da indução da hipovolemia experimental (T45 e após 30 minutos da indução anestésica (T75. RESULTADOS: A pressão intra-ocular apresentou relação direta somente com a pressão parcial de CO2 no final da expiração. CONCLUSÕES: Não foi possível estabelecer correlação entre alterações da pressão arterial média e da pressão venosa central com a pressão intra-ocular e houve relação direta entre os valores da pressão intra-ocular e os de ETCO2.PURPOSE: To observe the behavior of intraocular pressure according to the cardiopulmonary and hemodynamic effects induced by desflurane in dogs subjected to experimental hypovolemia. METHODS: Eighteen healthy male and female mongrel dogs, weighing between 10 and 15 kg were used. Hypovolemia was induced by withdrawal of 40 ml blood/kg body weight. Then anesthesia was induced with desflurane by mask until tracheal intubation was permitted. Intraocular pressure was measured with applanation tonometry. Heart rate, cardiac output, mean arterial pressure, central venous pressure, end-tidal concentration

  18. Avaliação da microbiota ocular em pacientes com disfunção do filme lacrimal Evaluation of conjunctival flora in patients with tear film dysfunction

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    Melissa Megumi Tomimatsu

    2009-12-01

    Full Text Available OBJETIVO: Avaliar a microbiota conjuntival em olhos com disfunção do filme lacrimal, e a modificação desta microbiota após a colocação de plug de silicone no canalículo inferior. MÉTODOS: Série de casos intervencionais não comparativos para avaliar 68 olhos de 41 pacientes com disfunção do filme lacrimal, durante o período de 2002 a 2007, na Universidade Federal de São Paulo. Todos os pacientes foram submetidos à colheita de amostras de raspado conjuntival de fundo-de-saco inferior para cultivo em Brain heart infusion broth. Os vinte e dois pacientes submetidos à colocação de plug de silicone repetiram a colheita de raspado conjuntival um mês após o procedimento. RESULTADOS: Dos 68 olhos avaliados, 47 apresentaram crescimento bacteriano nas amostras colhidas. Nove diferentes espécies de bactérias foram identificadas: Staphylococcus coagulase negativa em 66,66%, Staphylococcus aureus em 13,72%, Corynebacterium sp em 5,86%, Enterobacter aerogenes em 3,92%, Streptococcus hemolítico do grupo viridans em 1,96%, Serratia sp em 1,96%, Alcaligenes xylosoxidans spp em 1,96%, Corynebacterium xerosis em 1,96%, e Proteus mirabilis em 1,96%. Staphylococcus coagulase negativa (SCN foi o microrganismo mais frequentemente isolado tanto antes quanto após o plug de silicone. A sensibilidade do SCN à Oxacilina antes da colocação do plug era de 87,50%, e, após, de 73,68%. CONCLUSÃO: A microbiota em olhos com disfunção do filme lacrimal é bastante semelhante à encontrada em olhos normais. A resistência de SCN à Oxacilina foi um pouco maior após o implante do plug de silicone.PURPOSE: To evaluate conjunctival microbiota in eyes with tear film dysfunction and its modification after punctal occlusion with silicone plug. METHODS: Non comparative interventional case series study to evaluate 68 eyes of 41 patients with tear film dysfunction, from 2002 to 2007, followed in Federal University of Sao Paulo. Samples for culture were all

  19. Hipertensão intracraniana com manifestações oculares associada ao uso de tetraciclina: relato de caso Intracranial hypertension with ocular manifestation during the use of tetracycline: case report

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    Frederico Xavier dos Santos

    2005-10-01

    Full Text Available Os autores relatam o caso de uma paciente jovem, do sexo feminino, que desenvolveu quadro de hipertensão intracraniana benigna com manifestações oculares em concomitância ao uso de tetraciclina para o tratamento de otite. Esta é uma reação adversa rara deste medicamento, descrito em bula e com alguns relatos de caso em literatura internacional.The authors describe a young female patient with intracranial hypertension associated with ocular manifestations, during treatment with tetracycline. This is a rare adverse effect described in the medication warnings, and in a few reported cases in the scientific literature.

  20. Purinergic Receptors in Ocular Inflammation

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    Ana Guzman-Aranguez

    2014-01-01

    Full Text Available Inflammation is a complex process that implies the interaction between cells and molecular mediators, which, when not properly “tuned,” can lead to disease. When inflammation affects the eye, it can produce severe disorders affecting the superficial and internal parts of the visual organ. The nucleoside adenosine and nucleotides including adenine mononucleotides like ADP and ATP and dinucleotides such as P1,P4-diadenosine tetraphosphate (Ap4A, and P1,P5-diadenosine pentaphosphate (Ap5A are present in different ocular locations and therefore they may contribute/modulate inflammatory processes. Adenosine receptors, in particular A2A adenosine receptors, present anti-inflammatory action in acute and chronic retinal inflammation. Regarding the A3 receptor, selective agonists like N6-(3-iodobenzyl-5′-N-methylcarboxamidoadenosine (CF101 have been used for the treatment of inflammatory ophthalmic diseases such as dry eye and uveoretinitis. Sideways, diverse stimuli (sensory stimulation, large intraocular pressure increases can produce a release of ATP from ocular sensory innervation or after injury to ocular tissues. Then, ATP will activate purinergic P2 receptors present in sensory nerve endings, the iris, the ciliary body, or other tissues surrounding the anterior chamber of the eye to produce uveitis/endophthalmitis. In summary, adenosine and nucleotides can activate receptors in ocular structures susceptible to suffer from inflammatory processes. This involvement suggests the possible use of purinergic agonists and antagonists as therapeutic targets for ocular inflammation.

  1. The ocular surface chemical burns.

    Science.gov (United States)

    Eslani, Medi; Baradaran-Rafii, Alireza; Movahedan, Asadolah; Djalilian, Ali R

    2014-01-01

    Ocular chemical burns are common and serious ocular emergencies that require immediate and intensive evaluation and care. The victims of such incidents are usually young, and therefore loss of vision and disfigurement could dramatically affect their lives. The clinical course can be divided into immediate, acute, early, and late reparative phases. The degree of limbal, corneal, and conjunctival involvement at the time of injury is critically associated with prognosis. The treatment starts with simple but vision saving steps and is continued with complicated surgical procedures later in the course of the disease. The goal of treatment is to restore the normal ocular surface anatomy and function. Limbal stem cell transplantation, amniotic membrane transplantation, and ultimately keratoprosthesis may be indicated depending on the patients' needs.

  2. Cerebellum and Ocular Motor Control

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    Amir eKheradmand

    2011-09-01

    Full Text Available An intact cerebellum is a prerequisite for optimal ocular motor performance. The cerebellum fine-tunes each of the subtypes of eye movements so they work together to bring and maintain images of objects of interest on the fovea. Here we review the major aspects of the contribution of the cerebellum to ocular motor control. The approach will be based on structural-functional correlation, combining the effects of lesions and the results from physiologic studies, with the emphasis on the cerebellar regions known to be most closely related to ocular motor function: 1 the flocculus/paraflocculus for high-frequency (brief vestibular responses, sustained pursuit eye movements and gaze-holding, 2 the nodulus/ventral uvula for low-frequency (sustained vestibular responses, and 3 the dorsal oculomotor vermis and its target in the posterior portion of the fastigial nucleus (the fastigial oculomotor region for saccades and pursuit initiation.

  3. The Ocular Surface Chemical Burns

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    Medi Eslani

    2014-01-01

    Full Text Available Ocular chemical burns are common and serious ocular emergencies that require immediate and intensive evaluation and care. The victims of such incidents are usually young, and therefore loss of vision and disfigurement could dramatically affect their lives. The clinical course can be divided into immediate, acute, early, and late reparative phases. The degree of limbal, corneal, and conjunctival involvement at the time of injury is critically associated with prognosis. The treatment starts with simple but vision saving steps and is continued with complicated surgical procedures later in the course of the disease. The goal of treatment is to restore the normal ocular surface anatomy and function. Limbal stem cell transplantation, amniotic membrane transplantation, and ultimately keratoprosthesis may be indicated depending on the patients’ needs.

  4. [Ocular Behçet].

    Science.gov (United States)

    Alami, Ahmed; Kriet, Mohamed; Reda, Karim; Laktaoui, Abdelkader; Oubaaz, Abdelbaare

    2017-01-01

    Our study aimed to determine the clinical, therapeutic and prognostic features of ocular involvement in patients with Behçet's disease treated in our Department of ophthalmology. We conducted a retrospective data collection from medical records of 20 patients treated at the military hospital in Laayoune. All patients underwent complete ophthalmological examination and fluorescein angiography if necessary. OCT exam was performed in two patients. Ten patients had anterior uveitis, complicated in one case by ocular hypertonia; two patients had intermediate uveitis; eight patients had posterior segment involvement complicated in one case by intravitreal hemorrhage. Behcet's Disease (BD) is an systemic idiopathic inflammatory disease currently classified within primary non-necrotizing vasculitis. Ocular involvement is common and severe in Behçet's disease, with the potential to compromise the visual prognosis. Behcet's disease is common in Morocco. It can compromise patient's visual prognosis making the collaboration between ophthalmologists and internists particularly important.

  5. [Ultrasonographic findings in ocular toxocariasis].

    Science.gov (United States)

    Morais, Fábio Barreto; Maciel, Ana Lúcia; Arantes, Tiago Eugênio Farias e; Muccioli, Cristina; Allemann, Norma

    2012-01-01

    To evaluate ophthalmic ultrasound findings in the three presentation forms of ocular toxocariasis (peripheral or posterior pole granulomas and chronic endophthalmitis), in patients with confirmed diagnosis of ocular toxocariasis. 11 patients (11 eyes) with clinical and confirmed diagnosis of active ocular toxocariasis, presented positive ELISA test, were analyzed, prospectively, in the study. The patients were submitted to an ocular ultrasound examination (10-MHz transducer, contact technique). In the series of 11 patients, mean age was 7.9 years-old (range from 2 to 17 y), 73% male, referring previous contact with dogs (91%), and with the soil (50%), no referral of appetite perversion. In the analyses of compromised eyes (11 eyes), the ophthalmoscopic examination revealed the following distribution of the 3 forms of ocular toxocariasis: 7 cases (63.6%), posterior pole granuloma; 1 (9.1%), chronic endophthalmitis; 2 (18.2%), peripheral granuloma; and 1 (9.1%), posterior pole granuloma associated with chronic endophthalmitis. Visual acuity impairment: no light perception (3 eyes, 27.3%); hand motion (4 eyes, 36.4%); counting fingers at 10 cm (1 eye, 9.1%); 20/200 (1 eye, 9.1%); 20/70 (1 eye, 9.1%); undefined (1 eye, 9.1%). Serology was positive to Toxocara canis (ELISA test) in 100% of the cases. Ophthalmoscopy was difficult or impossible in 64% of the cases due to the media opacity. Ultrasound findings noted were vitreous membranes with retinal attachment (100%); parietal lesions (granulomas) with high (80%) or medium (20%) reflectivity. The most consistent ultrasound finding in the eye with toxocariasis was a high-reflectivity retinal mass, located in posterior pole or periphery, which may be calcified, and which has as main characteristic the adherence of vitreous membranes. In addition to clinical history, systemic evaluation and serology, the ultrasound can help in the diagnosis of ocular toxocariasis, especially in media opacities.

  6. Comparação da análise da frente de onda e da sensibilidade ao contraste em olhos pseudofácicos com implante de lentes intra-oculares esférica e asférica Wavefront analysis and contrast sensitivity comparison between spheric and aspheric intraocular lenses

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    Wilson Takashi Hida

    2008-06-01

    Full Text Available OBJETIVO: Comparar a análise da frente de onda e a sensibilidade de contraste pós-operatórias em pacientes submetidos à facoemulsificação com implante de lentes intra-oculares esféricas num olho e asféricas no olho contralateral. MÉTODOS: Este estudo prospectivo comparativo, randomizado, duplo-cego, incluiu 32 olhos de 16 pacientes. Uma avaliação oftalmológica completa foi realizada durante as visitas antes e depois da cirurgia (no primeiro, terceiro, sétimo, e nonagésimo dias pós-cirúrgicos, que incluiu acuidade visual, teste de sensibilidade ao contraste, aberrometria. Todos exames (menos aberrometr=ia foram feitos monocularmente com pupilas não dilatadas. Os pacientes foram submetidos a facectomia ultra-sônica convencional com implante de uma lente asférica SN60WF num olho e esférica SN60ATno outro. RESULTADOS: A acuidade visual média com a melhor correção foi -0,146 LogMAR no grupo da lente intra-ocular esférica, e -0.165 logMAR no grupo da lente intra-ocular asférica sob condições fotópicas, -0,003 LogMAR sob condições mesópicas. A sensibilidade ao contraste foi semelhante em ambos os grupos tanto em condições fotópicas e mesópicas. Em relação às aberrações ópticas ocorreu uma diferença significativa nas aberrações totais (1,09 ± 0,56 no grupo asférico e 1,52 ± 1,19 no grupo esférico e no componente esférico das aberrações de alta ordem(0,422 ± 0,202 no grupo asférico e 0,124 ± 0,087 no grupo esférico. CONCLUSÃO: As duas lentes intra-oculares promoveram uma excelente visão em situações de alto contraste, e os olhos implantados com a lente asférica tiveram menos aberrações totais e esféricas que aqueles implantados com a lente esférica.PURPOSE: Compare the wavefront and contrast sensitivity of bilateral pseudophakic patients with aspheric in one eye and spheric intraocular lenses in the other. METHODS: This prospective, comparative, randomized study, double masked, included 32

  7. Fluoroquinolone susceptibilities to methicillin-resistant and susceptible coagulase-negative Staphylococcus isolated from eye infection Suscetibilidade dos Staphylococcus coagulase negativo meticilina-resistentes e suscetíveis isolados em infecções oculares

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    Adália Dias Dourado Oliveira

    2007-03-01

    Full Text Available PURPOSE: To evaluate the fluoroquinolone susceptibilities of ocular isolate coagulase-negative staphylococci (CoNS, identified at the Microbiology Laboratory - UNIFESP. DESIGN: Experimental laboratory investigation. METHODS: The minimum inhibitory concentrations (MICs of 21 strains of methicillin-resistant coagulase-negative staphylococci (MRCoNS and 22 methicillin-sensitive coagulase-negative staphylococci (MSCoNS to ciprofloxacin, ofloxacin, gatifloxacin and moxifloxacin were determined, using the E-test method standardized by the Clinical and Laboratory Standards Institute (CLSI/NCCLS. RESULTS: The MIC90s (µg/ml for the second generation of tested fluoroquinolones were higher than the fourth generation, especially for the methicillin-resistant coagulase-negative staphylococci group. CONCLUSION: Our results indicate that methicillin-sensitive coagulase-negative staphylococci are more susceptible to quinolones than are methicillin-resistant coagulase-negative staphylococci and that fourth generation fluoroquinolones appear to be more potent, affecting even coagulase-negative staphylococcal strains resistant to second generation fluoroquinolones.OBJETIVOS: Avaliar a suscetibilidade a fluorquinolonas dos Staphylococcus coagulase-negativo (SCoN identificados no Laboratório de Microbiologia Ocular da Unifesp. MÉTODOS: Foi determinada a concentração inibitória mínima de 21 cepas de SCoN meticilina-resistentes e 22 meticilina-sensíveis para ciprofloxacina, ofloxacina, gatifloxacina e moxifloxacina, utilizando o E-test estandartizado pelo CLSI/NCCLS. RESULTADOS: Os MIC90 (µg/ml de 43 SCoN isolados para fluorquinolonas de segunda geração foram maiores do que os de quarta geração, principalmente para o grupo dos meticilina-resistentes. CONCLUSÃO: Nossos resultados indicam que Staphylococcus coagulase-negativo meticilina-sensíveis são mais suscetíveis às quinolonas do que os Staphylococcus coagulase-negativo meticilina

  8. Ocular manifestation in canine leishmaniasis

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    Ralić Marjan

    2011-01-01

    Full Text Available This paper presents a case of ocular changes in leishmaniasis in a dog brought in for examination because of visible changes in the eyes. An ocular manifestation in leishmaniasis can be bilateral or unilateral. Changes most often occur on the conjunctive and the front segment of the eye, the cornea and iris. From 70 to 80% of dogs diseased with leishmaniasis exhibit frontal uveitis, and dry eye, keratoconjunctivitis sicca, is also a frequent finding. Based on the clinical picture and the positive immunochromatographic rapid test it was established that the dog was diseased with leishmaniasis.

  9. [Adverse ocular effects of vaccinations].

    Science.gov (United States)

    Ness, T; Hengel, H

    2016-07-01

    Vaccinations are very effective measures for prevention of infections but are also associated with a long list of possible side effects. Adverse ocular effects following vaccination have been rarely reported or considered to be related to vaccinations. Conjunctivitis is a frequent sequel of various vaccinations. Oculorespiratory syndrome and serum sickness syndrome are considered to be related to influenza vaccinations. The risk of reactivation or initiation of autoimmune diseases (e. g. uveitis) cannot be excluded but has not yet been proven. Overall the benefit of vaccination outweighs the possible but very low risk of ocular side effects.

  10. Epidemiological profile of penetrating ocular trauma before and after the new traffic code

    OpenAIRE

    Paulo Caldas Silber; Luciene Barbosa de Souza; Maira Tiyomi Sacata Tongu

    2002-01-01

    Objetivo: Comparar o perfil epidemiológico dos pacientes com trauma ocular penetrante (TOP) antes e após a regulamentação do novo código de trânsito. Métodos: Estudo retrospectivo de 253 pacientes com TOP examinados na Seção de Trauma Ocular (UNIFESP) de janeiro de 1997 a abril de 1999. Os pacientes foram divididos em dois grupos: Grupo I, pacientes com trauma ocular antes da implantação do novo código; Grupo II, história de trauma após sua implantação. Os pacientes foram avaliados em relação...

  11. Tumor ocular metastásico Metastatic ocular tumor

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    Martha G Domínguez Expósito

    2004-06-01

    Full Text Available El carcinoma metastásico del ojo es considerado la neoplasia maligna que más frecuente se encuentra de forma intraocular. Solo cerca del 10 % de las personas que tienen una o más lesiones metastásicas intraoculares son detectadas clínicamente antes de la muerte. A menudo, el carcinoma metastásico ocular es diagnosticado por el oftalmólogo ante la presencia de síntomas oculares. Las lesiones están localizadas con preferencia en coroides. Nos motivo a realizar la presentación de este caso la presencia de lesiones intraoculares múltiples tumorales metastásicos en un paciente cuyo síntoma de presentación fue la disminución de la agudeza visualThe eye metastatic carcinoma is considered the most frequently found intraocular malignant neoplasia. Only 10 % of the persons with one or more metastatic intraocular injuries are clinically detected before death. The metastatic ocular carcinoma is often diagnosed by the ophthalmologist in the presence of ocular symptoms. The injuries are preferably located in the choroid. The appearance of multiple metastatic intraaocular tumoral injuries in a patient whose chief complaint was the reduction of visual acuity motivated us to presente this case

  12. Sonographic measurements of ocular biometry of indigenous ...

    African Journals Online (AJOL)

    Sonographic measurements of ocular biometry of indigenous Nigerian dogs in Zaria, Nigeria. ... The dogs were adequately restrained physically and the structure of the ocular globe was evaluated at a depth of 4-6 cm. For each dog ... Keywords: Ultrasonography, Baseline Value, Nigerian indigenous Dog, Ocular Biometry ...

  13. Alterações oculares associadas ao "bungee jumping": relato de caso Ocular alterations associated with bungee jumping: case report

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    José Ricardo Diniz

    2005-12-01

    Full Text Available Com a popularização do "bungee jumping" vem se observando aumento na ocorrência de lesões associadas a sua prática, entre elas lesões oculares. O objetivo deste relato é descrever um caso de diminuição aguda da acuidade visual e alterações campimétricas após "bungee jumping". Os autores apresentam o caso de paciente de sexo feminino, 48 anos, sem história de doença ocular ou sistêmica, que chega a consulta em emergência oftalmológica com queixa de baixa da acuidade visual após "bungee jumping", apresentando ao exame oftalmológico inicial, hemorragias em pólo posterior de ambos os olhos. A angiografia fluoresceínica apresentava áreas hipofluorescentes, por bloqueio do contraste, correspondendo às hemorragias, sem outras alterações vasculares. Avaliada após 14 semanas, observou-se reabsorção das hemorragias e rarefação do epitélio pigmentar da retina em pólo posterior; evoluiu clinicamente com melhora da visão, mas permaneceu com queixa de escotoma e alterações campimétricas mesmo cinco meses após o evento inicial. A ocorrência de lesões corporais, entre elas lesões oculares, com risco de diminuição da acuidade visual deve ser informada aos candidatos à prática deste esporte, sendo papel do oftalmologista prover informações à população em geral sobre possíveis afecções oculares, neste esporte e no cotidiano.The popularization of bungee jumping is causing an increase in occurrences of lesions associated with its practice, including ocular lesions. The purpose of this study is to describe a case of acute decrease in vision and visual field defects following a bungee jump. The authors present a case of a 48-year-old woman, without history of systemic or ocular disorders, seen at an ophthalmologic emergency service with visual loss complaint following a bungee jump. On initial ophthalmologic evaluation, hemorrhages in the posterior pole of both eyes were found. Fluorescein angiography showed

  14. Análise ultraestrutural e de fatores de crescimento de diferentes métodos de preservação da membrana amniótica utilizada em cirurgia ocular Ultrastructural and growth factor analysis of amniotic membrane preserved by different methods for ocular surger

    Directory of Open Access Journals (Sweden)

    Janethe Deolinda de Oliveira Pena

    2007-10-01

    Full Text Available OBJETIVO: Comparar, por microscopia eletrônica, a integridade anatômica e a presença de fatores de crescimento e citocinas da membrana amniótica preservada com glicerol/MEM (1:1 e dimetilsulfóxido puro. MÉTODOS: As membranas amnióticas preservadas em glicerol/MEM (1:1 ou dimetilsulfóxido puro foram processadas para microscopia eletrônica de transmissão e varredura. Como controle, membrana amniótica fresca foi imediatamente fixada após coleta e processada para microscopia eletrônica. As citocinas e os fatores de crescimento avaliados foram: TGF-beta- fator transformador de crescimento beta; TGF-beta ativ- fator transformador de crescimento beta ativado; EGF- fator recombinante de crescimento epitelial humano; FGF-4- fator de crescimento fibroblástico 4; FGF-beta- fator de crescimento fibroblástico básico; IL-4- interleucina 4; PGE2- prostaglandina E2; IL-10- interleucina 10; KGF- fator de crescimento de queratinócito; HGF- fator de crescimento de hepatócito. RESULTADOS: As membranas amnióticas do grupo controle apresentavam epitélio íntegro, com microvilos na superfície e complexos juncionais entre as células e a membrana basal. As membranas amnióticas preservadas em glicerol/MEM tinham aspecto semelhante às do controle, com maior altura das células epiteliais. Já as membranas amnióticas preservadas em dimetilsulfóxido mostraram redução das junções intercelulares e destacamento do epitélio da membrana basal. As citocinas e fatores de crescimento não apresentaram diferenças entre os grupos, exceto FGF-4, FGF-beta, PGE2 e KGF. CONCLUSÕES: A membrana amniótica preservada em meio glicerol/MEM apresentou melhor integridade tecidual, com menor desprendimento do epitélio da membrana basal, em comparação com a preservada no dimetilsulfóxido puro. Os fatores de crescimento e citocinas estavam, em sua maior parte, preservados com as duas técnicas de preservação.PURPOSE: To compare the anatomical structure and

  15. A reinserção escolar na área de oncologia infantil – avanços & perspectivas

    Directory of Open Access Journals (Sweden)

    Ana Carolina Carvalho Rocha Paterlini

    2008-12-01

    Full Text Available A proposta deste estudo é um ensaio sobre o tema, mencionando alguns avanços e perspectivas no que tange à reinserção escolar dessas crianças. É importante que a criança com câncer mantenha sua escolaridade, preservando sua vida normal, seu desenvolvimento integral e tenha esperança de cura para construir seu futuro. Porém, sua reinserção escolar tem sido difícil para professores, familiares e para ela própria. Os professores enfrentam dificuldades em como lidar com esta criança frente aos seus colegas de classe e relacionadas à falta de informação sobre a doença. Os familiares sofrem com a preocupação diante da integridade física e emocional da criança, preferindo, muitas vezes, mantê-las em casa. Já as crianças lidam com a desinformação, curiosidade e zombaria, face às mudanças na sua aparência física (perda de peso, queda de cabelo e uso de máscara.

  16. The Relationship Between Ocular Itch, Ocular Pain, and Dry Eye Symptoms (An American Ophthalmological Society Thesis).

    Science.gov (United States)

    Galor, Anat; Small, Leslie; Feuer, William; Levitt, Roy C; Sarantopoulos, Konstantinos D; Yosipovitch, Gil

    2017-08-01

    To evaluate associations between sensations of ocular itch and dry eye (DE) symptoms, including ocular pain, and DE signs. A cross-sectional study of 324 patients seen in the Miami Veterans Affairs eye clinic was performed. The evaluation consisted of questionnaires regarding ocular itch, DE symptoms, descriptors of neuropathic-like ocular pain (NOP), and evoked pain sensitivity testing on the forehead and forearm, followed by a comprehensive ocular surface examination including corneal mechanical sensitivity testing. Analyses were performed to examine for differences between those with and without subjective complaints of ocular itch. The mean age was 62 years with 92% being male. Symptoms of DE and NOP were more frequent in patients with moderate-severe ocular itch compared to those with no or mild ocular itch symptoms. With the exception of ocular surface inflammation (abnormal matrix metalloproteinase 9 testing) which was less common in those with moderate-severe ocular itch symptoms, DE signs were not related to ocular itch. Individuals with moderate-severe ocular itch also demonstrated greater sensitivity to evoked pain on the forearm and had higher non-ocular pain, depression, and post-traumatic stress disorders scores, compared to those with no or mild itch symptoms. Subjects with moderate-severe ocular itch symptoms have more severe symptoms of DE, NOP, non-ocular pain and demonstrate abnormal somatosensory testing in the form of increased sensitivity to evoked pain at a site remote from the eye, consistent with generalized hypersensitivity.

  17. Imaging the ocular motor nerves.

    NARCIS (Netherlands)

    Ferreira, T.; Verbist, B.M.; Buchem, M. van; Osch, T. van; Webb, A.

    2010-01-01

    The ocular motor nerves (OMNs) comprise the oculomotor, trochlear and the abducens nerves. According to their course, they are divided into four or five anatomic segments: intra-axial, cisternal, cavernous and intra-orbital and, for the abducens nerve, an additional interdural segment. Magnetic

  18. Ultraviolet light and ocular diseases.

    Science.gov (United States)

    Yam, Jason C S; Kwok, Alvin K H

    2014-04-01

    The objective of this study is to review the association between ultraviolet (UV) light and ocular diseases. The data are sourced from the literature search of Medline up to Nov 2012, and the extracted data from original articles, review papers, and book chapters were reviewed. There is a strong evidence that ultraviolet radiation (UVR) exposure is associated with the formation of eyelid malignancies [basal cell carcinoma (BCC) and squamous cell carcinoma (SCC)], photokeratitis, climatic droplet keratopathy (CDK), pterygium, and cortical cataract. However, the evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, ocular surface squamous neoplasia (OSSN), and ocular melanoma remained limited. There is insufficient evidence to determine whether age-related macular degeneration (AMD) is related to UV exposure. It is now suggested that AMD is probably related to visible radiation especially blue light, rather than UV exposure. From the results, it was concluded that eyelid malignancies (BCC and SCC), photokeratitis, CDK, pterygium, and cortical cataract are strongly associated with UVR exposure. Evidence of the association between UV exposure and development of pinguecula, nuclear and posterior subcapsular cataract, OSSN, and ocular melanoma remained limited. There is insufficient evidence to determine whether AMD is related to UV exposure. Simple behaviural changes, appropriate clothing, wearing hats, and UV blocking spectacles, sunglasses or contact lens are effective measures for UV protection.

  19. Ocular Vestibular Evoked Myogenic Potentials

    Directory of Open Access Journals (Sweden)

    Felipe, Lilian

    2014-01-01

    Full Text Available Introduction Diagnostic testing of the vestibular system is an essential component of treating patients with balance dysfunction. Until recently, testing methods primarily evaluated the integrity of the horizontal semicircular canal, which is only a portion of the vestibular system. Recent advances in technology have afforded clinicians the ability to assess otolith function through vestibular evoked myogenic potential (VEMP testing. VEMP testing from the inferior extraocular muscles of the eye has been the subject of interest of recent research. Objective To summarize recent developments in ocular VEMP testing. Results Recent studies suggest that the ocular VEMP is produced by otolith afferents in the superior division of the vestibular nerve. The ocular VEMP is a short latency potential, composed of extraocular myogenic responses activated by sound stimulation and registered by surface electromyography via ipsilateral otolithic and contralateral extraocular muscle activation. The inferior oblique muscle is the most superficial of the six extraocular muscles responsible for eye movement. Therefore, measurement of ocular VEMPs can be performed easily by using surface electrodes on the skin below the eyes contralateral to the stimulated side. Conclusion This new variation of the VEMP procedure may supplement conventional testing in difficult to test populations. It may also be possible to use this technique to evaluate previously inaccessible information on the vestibular system.

  20. Ocular Toxoplasmosis: Lessons from Brazil

    Science.gov (United States)

    • A new attention to post-natally acquired infections. Previously, most attention was focused on infection during pregnancy, and the risk of congenital disease, with the feeling that infection in older individuals was benign, without a substantial risk of disease morbidity, such as ocular involvemen...

  1. Ocular complications of malaria treatment

    African Journals Online (AJOL)

    2011-10-08

    Oct 8, 2011 ... Malaria is endemic in Nigeria. With the emergence of chloroquine resistance various modes of treatment including parenteral quinine are employed with consequent untoward effects. This article reports two cases of severe ocular toxicity, including mimicry of intracranial space-occupying lesion, from ...

  2. Lymphomatoid granulomatosis with ocular involvement.

    Science.gov (United States)

    Tse, D T; Mandelbaum, S; Chuck, D A; Nichols, P W; Smith, R E

    1985-01-01

    Lymphomatoid granulomatosis is an angiocentric and angiodestructive lymphoproliferative disorder that involves multiple organs including the lung, skin, kidney and central nervous system. A case of lymphomatoid granulomatosis with ocular involvement is reported herein. Bilateral peripheral retinal vasculitis involving both arterioles and veins, with posterior uveitis, is the prominent clinical finding.

  3. Estado da arte em oncologia médica: tumores da cabeça e do pescoço

    OpenAIRE

    Canelas, Inês Cravidão Prates

    2013-01-01

    Dissertação para obtenção do grau de Mestre no Instituto Superior de Ciências da Saúde Egas Moniz O cancro da cabeça e do pescoço é considerado o sexto tipo de cancro mais comum na Europa e afeta sobretudo o sexo masculino. O principal fator de risco associado ao aparecimento deste tipo de cancro é o tabagismo. No entanto o consumo de álcool e as infeções pelo vírus do papiloma humano (HPV) também se encontram intimamente relacionados com o aumento do risco de adquirir cancro da cabeça ...

  4. As práticas do cuidar na oncologia: a experiência da fisioterapia em pacientes com câncer de mama

    OpenAIRE

    Faria,Lina

    2010-01-01

    A fisioterapia oncológica precoce vem desempenhando um importante papel na prevenção e minimização dos efeitos adversos do tratamento do câncer de mama, que acomete um grande número de mulheres. A fisioterapia reduz os riscos de complicações e pode restaurar a integridade cinético-funcional de órgãos e sistemas. A fisioterapia oncológica, ao enfatizar os caminhos da prevenção, tem ampliado a atuação do fisioterapeuta e consolidado seu espaço legítimo no campo médico, complementando as habilid...

  5. [Role of ocular pulse amplitude in glaucoma].

    Science.gov (United States)

    Stürmer, J P E; Kniestedt, C

    2015-02-01

    The ocular pulse amplitude is defined as the difference between diastolic and systolic intraocular pressure. The ocular pulse is generated by the pulsatile ocular blood flow in the choroid. It is dependent on the dynamics of the cardiovascular system, the rigidity of the ocular vessels on one side and the biomechanical properties of the eye on the other side. In addition the influence of outflow facility of the aqueous humor, the level of the intraocular pressure itself and last but not least the rigidity of the sclera on the ocular pulse amplitude is until now not clear. Dynamic contour tonometry (Pascal®) does not only measure intraocular pressure almost independent of corneal thickness and curvature but also allows easy and fast measurement of ocular pulse amplitude on the slit lamp. The ocular pulse amplitude in healthy subjects is between 1.2 and 4 mmHg. If the ocular pulse amplitude is larger than 1.2 mmHg spontaneous pulsations of the central retinal vein are visible on fundoscopy. In patients with ocular hypertension the ocular pulse amplitude is larger than in normal subjects but this is mainly due to higher IOP levels. In patients with manifest open-angle glaucoma the ocular pulse amplitude stays initially within the normal range. In more advanced stages of the disease and especially in patients with ocular perfusion pressure dependent optic neuropathy the ocular pulse amplitude is gradually reduced. Due to the various factors influencing ocular pulse amplitude a direct correlation between reduced ocular pulse amplitude and reduced ocular perfusion pressure has not been established as yet. New approaches investigating the variations of the ocular pressure Fourier spectral analysis are promising, especially when simultaneous analysis of the arterial blood pressure is performed. These techniques may allow a fast and easy discrimination between healthy and glaucomatous patients in the near future. If ocular pulse amplitude exhibits a massive inter-ocular

  6. OCULAR MANIFESTATIONS OF HEAD INJURIES

    Directory of Open Access Journals (Sweden)

    Kanukollu Venkata Madusudana Rao

    2016-12-01

    Full Text Available BACKGROUND This prospective study aimed to evaluate the incidence of ocular manifestations in head injury and their correlation with the intracranial lesions. MATERIALS AND METHODS A total of 108 consecutive cases of closed head injury admitted in the neurosurgical ward of a tertiary teaching hospital underwent a thorough ophthalmic assessment. Clinical examination, radiological imaging and Glasgow Coma Scale (GCS were applied to grade the severity of injury. RESULTS Total number of 108 patients of head injury were examined of which 38 patients had ocular manifestations (35.18%. Of these, 85.18% were males, 84% of injuries were due to road traffic accidents and 16% were due to fall from a height. The ocular manifestations were as follows- Orbital complications were seen in 6 patients (15.8%. Anterior segment manifestations included black eyes seen in 10 patients (26.3%, subconjunctival haemorrhage in 10.5% of patients (4 patients, corneal involvement in 21% of patients (8 patients and pupillary involvement in 50% of patients (19 patients. Posterior segment manifestations were seen in 26.3% of patients (10 patients and were as follows- Purtscher’s retinopathy in 2 patients and optic atrophy in 5 patients. Cranial nerve palsies were seen in 15 patients (39.47% and supranuclear movement disorders were seen in 3 patients (8%. CONCLUSION Even though, neurosurgeons perform comprehensive clinical examination including eye examination, the main purpose is limited to aid topical diagnosis of neurological lesions. This study emphasises the importance of a detailed eye examination by an ophthalmologist to prevent irreversible visual loss in addition to aiding in the neurological diagnosis. Pupillary involvement, papilloedema and ocular motor paresis pointed to a more severe head injury. This observational prospective study helped us to correlate the severity of head injuries in association with ocular findings in patients admitted in neurosurgical ward

  7. Osteossarcoma: experiência do Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo Osteosarcoma: experience of the Pediatric Oncology clinic of the Santa Casa de Misericórdia Hospital in São Paulo

    Directory of Open Access Journals (Sweden)

    Helaine Cristina de Castro

    2008-04-01

    Full Text Available OBJETIVOS: Descrever as características clínico-laboratoriais das crianças e adolescentes com osteossarcoma acompanhadas no Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo e determinar as taxas de sobrevida livre de evento e sobrevida global, correlacionando-as com os principais fatores prognósticos. MÉTODOS: Estudo retrospectivo realizado no Serviço de Oncologia Pediátrica da Santa Casa de Misericórdia de São Paulo compreendendo o período entre abril de 1991 e setembro de 2002. Nesse período foram diagnosticados 60 casos de osteossarcoma. Observaram-se predomínio do sexo masculino (61,7%, raça não-branca (65% e idade superior a 10 anos (70%; história de trauma prévio em 53,3%, relato de dor em 95% e aumento de volume em 80% dos casos. O joelho foi a região mais comprometida (74,9%. Em 70,7% dos casos o tumor apresentava tamanho inferior a 1/3 do comprimento do osso afetado, em 25% o nível sérico de desidrogenase láctica era igual ou maior que 500U/L e em 48,3% o nível de fosfatase alcalina era igual ou maior que 1.000U/L, 25% dos pacientes apresentavam metástase pulmonar visível ao diagnóstico e 53,3% pertenciam ao subtipo osteoblástico. O tratamento quimioterápico pré e pós-operatório foi realizado em 78,3% dos pacientes, 64% foram submetidos a procedimento cirúrgico conservador, 68,1% apresentaram necrose tumoral graus I e II e houve recidiva em 60% dos casos. RESULTADOS: Com seguimento de 48 meses observaram-se sobrevida livre de doença em 28,6% dos pacientes e sobrevida global de 38,4%. CONCLUSÕES: Os autores concluem que o diagnóstico precoce é fundamental, assim como novos estudos são necessários para aprimorar o manuseio e o tratamento desses pacientes e melhorar a sobrevida.OBJECTIVES: To describe clinical and laboratorial features of children and adolescents with osteosarcoma seen at the Pediatric Oncology clinic of the Santa Casa de Misericórdia Hospital in São Paulo

  8. Morte digna da criança: percepção de enfermeiros de uma unidade de oncologia Muerte digna del niño: percepción de enfermeros de una unidad de oncología Dignified death for children: perceptions of nurses from an oncology unit

    Directory of Open Access Journals (Sweden)

    Luise Felix de Souza

    2013-02-01

    Full Text Available O objetivo deste estudo foi identificar o significado e as intervenções de enfermeiros que atuam em oncologia pediátrica na promoção de morte digna da criança. Utilizaram-se como referencial teórico e metodológico o interacionismo simbólico e a pesquisa de narrativa. Os dados foram coletados junto a oito enfermeiros de uma unidade de oncologia pediátrica de um hospital público de São Paulo, por meio de entrevistas semiestruturadas. A análise dos dados permitiu a identificação de cinco categorias: sentir-se sem autonomia para a tomada de decisão; cuidar da família; oferecer conforto físico; valorizar o cuidado humanizado e aprender a lidar com a morte e o morrer. Este estudo contribui para ampliar a compreensão do processo de cuidar e permite avançar na postulação de um quadro teórico que contemple a integração de saberes e ações que constituem uma assistência integral, transcendendo o atendimento de necessidades apenas clínicas e biológicas.Se objetivó identificar el significado y las intervenciones de enfermeros actuantes en oncología pediátrica en la promoción de la muerte digna del niño. Se utilizaron interaccionismo simbólico e investigación narrativa como referenciales teóricos y metodológicos. Datos obtenidos de ocho enfermeros de una unidad de oncología pediátrica de hospital público de São Paulo, mediante entrevistas semiestructuradas. El análisis permitió la identificación de cinco categorías: Sentirse sin autonomía para la toma de decisiones; Cuidado de la familia; Ofrecer bienestar físico; Valorizar el cuidado humanizado y Aprender a enfrentarse con la muerte y el morir. El estudio contribuye a ampliar la comprensión de éste proceso de cuidados y permite avanzar en la postulación de un cuadro teórico que contemple la integración de conocimientos y acciones que constituyan una atención integral, trascendiendo la atención de necesidades meramente clínicas y biol

  9. Manejo de variáveis psicológicas no tratamento do câncer em crianças: algumas contribuições da psiconeuroimunologia

    OpenAIRE

    Coutinho, Sílvia Maria Gonçalves; Costa Junior, Áderson L.; Kanitz,Suyane

    2000-01-01

    Estudos em psico-oncologia pediátrica apontam a necessidade de intervenções multiprofissionais sistemáticas que possam contribuir para a minimização de efeitos adversosproduzidospor diferentes situações do tratamentodo câncera que crianças e familiares são submetidos ou, preparar o paciente para enfrentar contextos identificados como de caráter estressante. O presente artigo apresenta os princípios básicos da psiconeuroimunologia e discute a funcionalidade de algumas contribuições desta área ...

  10. Desenvolvimento do olhar e do contato ocular em lactentes de zero a quatro meses de idade The development of looking behavior and eye-contact in breast feeding children aged between 0 and 4 months

    Directory of Open Access Journals (Sweden)

    Aline Elise Gerbelli Belini

    2010-03-01

    Full Text Available OBJETIVOS: investigar o desenvolvimento do contato ocular e do comportamento visual de bebês entre zero e quatro meses. MÉTODOS: dezessete bebês típicos foram filmados mensalmente por 30 minutos, sendo transcritas 11 categorias de observação do olhar, quantificadas e tratadas estatisticamente através dos testes de Friedman (α = 0,050 e dos Postos Sinalizados de Wilcoxon (α de Bonferroni = 0,010. RESULTADOS: houve diferenças estatisticamente significantes nas frequências das categorias: "olhar para os olhos da mãe" (pOBJECTIVES: to investigate the development of eye-contact and visual behavior in babies aged between 0 and 4 months. METHODS: sixteen normal babies were filmed monthly for 30 minutes, and 11 eleven visual behavior categories observed and transcribed. These were then quantified and treated statistically using the Friedman test (α = 0.050 and Wilcoxon's Signed Rank test (Bonferroni's α = 0,010. RESULTS: there were statistical differences in frequency between the various categories: "looking mother in the eye" (p<0.001, "looking mother in the face" (p<0.001, "looking at an object" (p<0.001, "looking at the researcher" (p<0.001, "actively looking at the surroundings" (p<0.001, "passively looking at the surroundings" (p<0.001, "looking at own body" (p=0.001 and "eyes closed" (p=0.005. Eye-contact was detected in the third week of life in 64.7% and developed during the first five months of life (p=0.010 in 50% of the intervals between data collection. CONCLUSIONS: eye-contact can be detected from the neonatal period onwards and develops over the first few months of life. The frequency of the baby's eye-contact with its mother increases longitudinally in the first four months. Other focuses of attention, apart from the mother's eyes, are also fundamental during the early stages of development outside the womb.

  11. Interfacial phenomena and the ocular surface.

    Science.gov (United States)

    Yañez-Soto, Bernardo; Mannis, Mark J; Schwab, Ivan R; Li, Jennifer Y; Leonard, Brian C; Abbott, Nicholas L; Murphy, Christopher J

    2014-07-01

    Ocular surface disorders, such as dry eye disease, ocular rosacea, and allergic conjunctivitis, are a heterogeneous group of diseases that require an interdisciplinary approach to establish underlying causes and develop effective therapeutic strategies. These diverse disorders share a common thread in that they involve direct changes in ocular surface chemistry as well as the rheological properties of the tear film and topographical attributes of the cellular elements of the ocular surface. Knowledge of these properties is crucial to understand the formation and stability of the preocular tear film. The study of interfacial phenomena of the ocular surface flourished during the 1970s and 1980s, but after a series of lively debates in the literature concerning distinctions between the epithelial and the glandular origin of ocular surface disorders during the 1990s, research into this important topic has declined. In the meantime, new tools and techniques for the characterization and functionalization of biological surfaces have been developed. This review summarizes the available literature regarding the physicochemical attributes of the ocular surface, analyzes the role of interfacial phenomena in the pathobiology of ocular surface disease, identifies critical knowledge gaps concerning interfacial phenomena of the ocular surface, and discusses the opportunities for the exploitation of these phenomena to develop improved therapeutics for the treatment of ocular surface disorders. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Oculoplastic aspects of ocular oncology.

    Science.gov (United States)

    Rene, C

    2013-02-01

    It is estimated that 5-10% of all cutaneous malignancies involve the periocular region and management of periocular skin cancers account for a significant proportion of the oculoplastic surgeon's workload. Epithelial tumours are most frequently encountered, including basal cell carcinoma, squamous cell carcinoma, and sebaceous gland carcinoma, in decreasing order of frequency. Non-epithelial tumours, such as cutaneous melanoma and Merkel cell carcinoma, rarely involve the ocular adnexae. Although non-surgical treatments for periocular malignancies are gaining in popularity, surgery remains the main treatment modality and has as its main aims tumour clearance, restoration of the eyelid function, protection of the ocular surface, and achieving a good cosmetic outcome. The purpose of this article is to review the management of malignant periocular tumours, with particular emphasis on surgical management.

  13. Clinical manifestations of ocular toxoplasmosis.

    Science.gov (United States)

    Delair, Emmanuelle; Latkany, Paul; Noble, A Gwendolyn; Rabiah, Peter; McLeod, Rima; Brézin, Antoine

    2011-04-01

    Clinical manifestations of ocular toxoplasmosis are reviewed. Findings of congenital and acute acquired ocular toxoplasmosis include retinal scars, white-appearing lesions in the active phase often associated with vitritis. Complications can include fibrous bands, secondary serous or rhegmatogenous retinal detachments, optic neuritis and neuropathy, cataracts, increased intraocular pressure during active infection, and choroidal neovascular membranes. Recurrences in untreated congenital toxoplasmosis occur in teenage years. Manifestations at birth are less severe, and recurrences are fewer in those who were treated promptly early in the course of their disease in utero and in the first year of life. Severe retinal involvement is common at diagnosis of symptomatic congenital toxoplasmosis in the United States and Brazil. Acute acquired infections also may be complicated by toxoplasmic retinochoroiditis, with recurrences most common close to the time of acquisition. Suppressive treatment can reduce recurrent disease.

  14. Perforating ocular injury by Taser.

    Science.gov (United States)

    Chen, Sandy L; Richard, Christen K; Murthy, Raghu C; Lauer, Andreas K

    2006-01-01

    This report describes the features, treatment and outcome of globe perforation by a Taser dart electrode in a 21-year-old man. The Taser electrode caused mechanical iris, lens and retinal injury and consequent retinal detachment as result of proliferative vitreoretinopathy. The effect of electrical stimulation on ocular tissues is unknown. After the scleral and corneal wounds, traumatic cataract and retinal tear were repaired, the patient regained a visual acuity of 6/18. Nine months later a retinal detachment with proliferative vitreoretinopathy was discovered. The Taser may cause globe perforation and posterior segment injury. Understanding the barbed configuration of the dart electrode is important when extricating this device. Visual recovery is possible despite electric discharge of the Taser and suggests that the mechanism of ocular injury is largely mechanical.

  15. Alterações oculares em micose fungóide associada com vírus linfotrópico de células t humanas tipo I Ocular fidings in mycosis fungoides associated with human t-lymphotropic virus type I

    Directory of Open Access Journals (Sweden)

    Epaminondas de Souza Mendes Junior

    2010-10-01

    Full Text Available São relatados dois casos da associação de micose fungóide e HTLV-I. Os achados oftalmológicos observados foram, no caso 1: ceratopatia ponteada e ceratoconjuntivite seca e; no caso 2: ceratoconjuntivite seca, espessamento e nódulos difusos em bordas palpebrais. A associação de micose fungóide e HTLV-I nos dois casos sugere envolvimento deste vírus na etiopatogenia da doença. Maior conhecimento e realização de estudos bem controlados poderão ser úteis na determinação precisa desta hipótese.Two cases of mycosis fungoides associated with HTLV-I are reported. The ophthalmological findings were, in the first case, punctate keratopathy and keratoconjunctivitis sicca, and in the second case, keratoconjunctivitis sicca, thickening and difuse nodulos on eyelid margin. The association of mycosis fungoides and HTLV-I in these cases suggests involvement of this agent in the pathogenesis of the disease.

  16. Alterações oculares em micose fungóide associada com vírus linfotrópico de células t humanas tipo I

    OpenAIRE

    Mendes Junior,Epaminondas de Souza; Guerra,Ricardo Luz Leitão; Palma,Leonora Cristina Leal; Marback,Eduardo Ferrari; Marback,Patrícia Maria Fernandes

    2010-01-01

    São relatados dois casos da associação de micose fungóide e HTLV-I. Os achados oftalmológicos observados foram, no caso 1: ceratopatia ponteada e ceratoconjuntivite seca e; no caso 2: ceratoconjuntivite seca, espessamento e nódulos difusos em bordas palpebrais. A associação de micose fungóide e HTLV-I nos dois casos sugere envolvimento deste vírus na etiopatogenia da doença. Maior conhecimento e realização de estudos bem controlados poderão ser úteis na determinação precisa desta hipótese....

  17. Oculoplastic aspects of ocular oncology

    OpenAIRE

    Rene, C

    2012-01-01

    It is estimated that 5–10% of all cutaneous malignancies involve the periocular region and management of periocular skin cancers account for a significant proportion of the oculoplastic surgeon's workload. Epithelial tumours are most frequently encountered, including basal cell carcinoma, squamous cell carcinoma, and sebaceous gland carcinoma, in decreasing order of frequency. Non-epithelial tumours, such as cutaneous melanoma and Merkel cell carcinoma, rarely involve the ocular adnexae. Alth...

  18. Processos perceptuais e cognitivos na leitura de palavras: propriedades dos movimentos oculares

    Directory of Open Access Journals (Sweden)

    Elizeu Coutinho de Macedo

    Full Text Available A análise do padrão do movimento ocular auxilia discriminar leitores competentes daqueles com dificuldades de leitura. O padrão de leitura dos movimentos oculares é afetado por propriedades psicolingüísticas da palavra, tais como: comprimento, regularidade, freqüência e lexicalidade O objetivo do presente estudo foi analisar o padrão de movimentos oculares durante a leitura em português do Brasil e compará-lo com resultados de estudos de outras línguas. Os movimentos oculares durante a leitura de palavras e pseudopalavras foram analisados em 20 universitários com idade média de 20,5 anos (DP=2,9. Os resultados indicam que o número de fixações, tempo da primeira fixação e tempo total das fixações foram influenciados pelas variáveis, comprimento, lexicalidade e freqüência dos itens. Foi observado efeito de regularidade para todas as variáveis, exceto naquela do número de fixações. Os resultados obtidos foram semelhantes àqueles encontrados em outras línguas com predomínio de palavras regulares, mas não de palavras irregulares, como o inglês.

  19. OCULAR MICROBIAL POPULATION AS A 2-1 BETAMETHASONE DISSODIC FOSPHATE AND DISSODIC FOSPHATE/ACETATE DEXAMETHASONE MONITOR IN SWINE CORNEA TRANSPLANTED DOGS ESTUDO DA MICROBIOTA OCULAR COMO MONITOR DO 2-1 FOSFATO DISSÓDICO DE BETAMETASONA E DO FOSFATO DISSÓDICO/ACETATO DE DEXAMETASONA, EM CÃES QUE RECEBERAM TRANSPLANTES COM CÓRNEAS DE SUÍNOS

    Directory of Open Access Journals (Sweden)

    Nilo Sérgio Troncoso Chaves

    2007-09-01

    Full Text Available

    Ten mixed breed dogs, with a 10 kg average weight, were selected at Centro de Zoonoses de Goiânia. After being examined and considered healthy, the dogs were enumerated from 11 to 20 on their collars. Each animal had swine cornea implanted into the left eye. The swine cornea was obtained at Casa de Banha Caçula, a slaughterhouse, and conserved in a humid chamber during a maximum 6 hour period. Before surgery, each animal received 4 mg dissodic fosphate/acetate of dexamethasone IM and one drop of betamethasone dissodic fosphate and gentamycin sulphate. This medication was kept until euthanasia. Each dog had a superior fornix sample collected, the sample was immersed in 0.1% peptonized water, so that tests for aerobic bacteria and fungus could be realized. Each test was repeated with samples collected on days 7, 14, 21 and 28, after graft, and compared with those from day 0. The 12.8% Staphylococcus epidermidis on initial samples was caused by contamination during collection because it wasn’t found on the 28th day samples. This fact suggests that, although corticosteroids had caused systemic imunocellular supression, they didn’t make easier the bacterial development into the grafted eye.

    KEY-WORDS: Microbial population; corticosteroids; xenotranplants; cornea; canine; swine.

    Foram utilizados dez cães, sem raça definida, com peso médio de 10kg, selecionados no Centro de Zoonoses da Prefeitura de Goiânia. Após examinados e considerados sadios, foram numerados de 11 a 20 na respectiva coleira. Cada cão, a seu tempo, teve implantada no olho esquerdo córnea de suíno, este abatido no frigorífico Casa de Banha Caçula. A córnea foi conservada em câmara úmida pelo

  20. Tumor vasoproliferativo associado à tuberculose ocular presumida: relato de caso Vasoproliferative tumor associated with presumed ocular tuberculosis: case report

    Directory of Open Access Journals (Sweden)

    Luciana Duarte Rodrigues

    2007-06-01

    Full Text Available OBJETIVO: Descrever um caso de tumor vasoproliferativo associado à tuberculose ocular tratado com crioterapia e injeção de triancinolona intravítrea. DESENHO DO ESTUDO/PACIENTES E MÉTODOS: Relato de caso intervencional. Paciente do sexo feminino, 42 anos, referia inflamação do olho direito havia 1 ano, não diagnosticada, tratada com prednisona oral por 30 dias. Relatava baixa visão com o olho direito (OD desde a infância. Negava antecedentes pessoais e familiares. Ao exame ocular, apresentava acuidade visual menor que 20/400 com o OD. Não apresentava alterações à biomicroscopia e a pressão intra-ocular era normal em ambos os olhos. A fundoscopia do OD mostrava lesão vascularizada, elevada, associada ao descolamento seroso e exsudatos duros, localizada na periferia inferior da retina. A lesão era cercada por extensa área de pontos de hiperplasia do epitélio pigmentar. A mácula apresentava diminuição do reflexo foveal. No exame de ultra-som ocular, a lesão apresentava altura igual a 2,25mm e consistência sugestiva de lesão vascularizada. Foram solicitados exames sorológicos, hemograma, RX tórax e PPD. Os exames foram normais, com exceção do PPD, considerado forte reator. A paciente foi encaminhada ao infectologista, que diagnosticou tuberculose após exame de pesquisa de BK no escarro. Em face do quadro clínico, foi feito o diagnóstico de tumor vasoproliferativo da retina associado à tuberculose ocular presumida. Iniciou-se o tratamento com esquema tríplice (rifampicina, isoniazida e piridoxina. Optou-se por tratar o tumor com crioterapia e injeção intravítrea de triancinolona (4 mg/ml. Após 30 dias, a paciente apresentava diminuição do descolamento seroso e áreas atróficas na lesão tumoral. O aspecto angiofluoresceinográfico mostrava algumas áreas de enchimento precoce da trama vascular com discreto extravasamento tardio do contraste, sem áreas de oclusão capilar. A maior parte da lesão apresentava

  1. Follicular lymphoma of the ocular adnexal region

    DEFF Research Database (Denmark)

    Rasmussen, Peter Kristian; Ralfkiaer, E.; Prause, J.U.

    2015-01-01

    Purpose To characterize the clinicopathological features of follicular lymphoma of the ocular adnexal region. Methods Retrospective nation-based study of Danish patients with ocular adnexal follicular lymphoma from January 1st 1980 through December 31st 2009. Results Twenty-four patients...... with ocular adnexal follicular lymphoma were identified. Fourteen (58%) of the patients were females. The median age was 63 years (range: 42–96 years). Eleven (46%) of the patients had primary ocular adnexal lymphoma, seven (29%) had an ocular adnexal lesion in conjunction with a concurrent systemic lymphoma...... and six patients (25%) presented with an ocular adnexal relapse. The most frequently affected sites were the lacrimal gland (38%) and the orbit (33%). Thirteen patients (54%) presented with Ann Arbor stage IE lymphoma, four (17%) had stage IIE, two patients (8%) stage IIIE, and five patients (21%) had...

  2. Ocular manifestations in children with cerebral palsy.

    Science.gov (United States)

    Sasmal, Nirmal Kumar; Maiti, Prasenjit; Mandal, Radhakrishna; Das, Debabrata; Sarkar, Subhra; Sarkar, Piyali; Biswas, Mukul Chandra; Dey, Asim Kumar; Chatterjee, Sanjay

    2011-05-01

    To evaluate the prevalence of ocular abnormalities among children with cerebral palsy, 140 patients with age between 6 months and 16 years were selected and the overall incidence of ocular abnormalities in this study was 42.1%. Two major ocular abnormalities identified in these cases were strabismus in 36.4%. Myopia was detected in 12.9% children while hypermetropia in 8.6% and astigmatism in 3.6% cases. Non-glaucomatous optic atrophy was present in 10.7% cases and nystagmus in 9.3% cases. Raised intra-ocular pressure was detected in 2.1% cases. Cortical visual impairment was seen in 20.7% children. Ocular abnormalities are frequent manifestations in cerebral palsy patients. Therefore, evaluation of all cerebral palsy cases emphasises the need for a full ophthalmological examination in order to detect ocular problems and to institute necessary therapy of the abnormalities for better livelihood of these physically challenged patients.

  3. Ocular myasthenia gravis: Side effect of urografin

    Directory of Open Access Journals (Sweden)

    Nitin Modi

    2016-01-01

    Full Text Available Ocular myasthenia gravis is an autoimmune disorder of the neuromuscular junction. Diplopia and ptosis are common symptoms at the onset of ocular myasthenia gravis. It may occur due to the antibodies developed against various drugs. We are reporting a case of ocular myasthenia gravis which was developed in a patient post angiography which may be due to antibody developed against the dye used in angiography.

  4. Myopic anisometropia: ocular characteristics and aetiological considerations

    National Research Council Canada - National Science Library

    Vincent, Stephen J; Collins, Michael J; Read, Scott A; Carney, Leo G

    2014-01-01

    Anisometropia represents a unique example of ocular development, where the two eyes of an individual, with an identical genetic background and seemingly subject to identical environmental influences...

  5. Medicina regenerativa y superficie ocular Regenerative medicine and ocular surface

    Directory of Open Access Journals (Sweden)

    Taimi Cárdenas Díaz

    2012-06-01

    Full Text Available En los últimos años se ha producido un extraordinario avance en los conocimientos relacionados con diferentes ramas biomédicas, entre ellas, la biología celular. Esto ha dado un notable impulso a una nueva rama de la medicina denominada medicina regenerativa. Esta nueva disciplina médica se basa fundamentalmente en los nuevos conocimientos sobre las células madre y en su capacidad de convertirse en células de diferentes tejidos. Una de las estructuras que tiene más interés, desde el punto de vista de la medicina regenerativa, es la superficie ocular. Por esto, se ha logrado notables progresos en la reconstrucción de la superficie ocular mediante la aplicación de procederes regenerativos. Los cultivos de células del epitelio corneal humano están siendo utilizados en el tratamiento de la insuficiencia limbar. Esto permite disminuir la incidencia de opacidades tipo Haze tras queratectomía fotorrefractiva, acelerar la curación y evitar la aparición de leucomas en pacientes con defectos epiteliares persistentes e intentar disminuir la incidencia de opacidades corneales en pacientes sometidos a queratectomía fototerapéutica por diferentes distrofias corneales.In the last few years, an extraordinary advance has taken place in the knowledge about several biomedical branches as is the case of cellular biology, which has remarkably encouraged the development of a new medical branch called regenerative medicine. This medical discipline is fundamentally based on the new knowledge on the stem cells and their capacity to become cells for different tissues. One of the most interesting structures for the regenerative medicine is the ocular surface. In the last few years, significant advances have been achieved in the field of the ocular surface reconstruction with regenerative procedures. Some cell cultures of the human corneal epithelium are being used to treat limber insufficiency, to reduce the incidence of haze-type opacities after

  6. Comparison of PMMA, foldable silicone and foldable acrylic hydrophobic intraocular lenses in combined phacoemulsification and trabeculectomy Comparação entre lentes intra-oculares de PMMA, lentes dobráveis de silicone e lentes acrílicas hidrofóbicas dobráveis em cirurgias combinadas de facoemulsificação e trabeculectomia

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    Ernani Serpa Junior

    2005-02-01

    Full Text Available PURPOSE: To compare the postoperative results of phacotrabeculectomy with implantation of PMMA, foldable silicone or foldable hydrofobic acrylic intraocular lens (IOL. SETTING: Glaucoma unit, The Royal Liverpool University Hospital, Liverpool, United Kingdom. METHODS: We studied a total of 124 eyes of three consecutive groups of patients with glaucoma and cataract that underwent phacotrabeculectomy with implantation of a PMMA (30 eyes, a foldable silicone (57 eyes or a foldable acrylic (37 eyes IOL. Postoperative Snellen visual acuity and intraocular pressure (IOP, and early and late complications were assessed. All data were analyzed by means of c² test, Fisher's exact test, ANOVA/MANOVA tests or a combination whenever appropriate. RESULTS: In all three groups the early and late mean postoperative IOPs were significantly lower than the preoperative ones (p25 mmHg and hypotony (IOPOBJETIVO: Comparar os resultados pós-operatórios de facotrabeculectomias com implante de lentes intra-oculares de PMMA, dobráveis de silicone e acrílicas hidrofóbicas dobráveis. MÉTODOS: Estudo comparativo retrospectivo, realizado no Departamento de Glaucoma da "St. Paul's Eye Unit - The Royal Liverpool University Hospital", em Liverpool, Inglaterra, onde foram estudados um total de 124 olhos de três grupos consecutivos de pacientes com glaucoma e catarata que foram submetidos à cirurgia de facotrabeculectomia com implante de lentes intra-oculares (LIO de PMMA (30 olhos, dobráveis de silicone (57 olhos e acrílicas hidrofóbicas dobráveis (37 olhos. Foram registradas a visão e pressão intra-ocular (PIO pré e pós-operatória, assim como as complicações pós-operatórias precoces e tardias. Todos os dados foram analisados utilizando-se o teste c², teste exato de Fisher, teste de ANOVA/MANOVA ou uma combinação deles quando necessário. RESULTADOS: Nos três grupos as PIOs pós-operatórias precoces e tardias foram significativamente inferiores

  7. AVALIAÇÃO DA HISTÓRIA FAMÍLIAR POR HEREDOGRAMA EM CÂNCER DE MAMA

    OpenAIRE

    MARIA HILDA ARAUJO RIBEIRO

    2009-01-01

    O câncer familial compreende a agregação de alguns tipos de câncer sem um padrão de herança bem definido. A genética do câncer é um componente essencial da prática clínica em oncologia. No Brasil, o câncer de mama é a principal causa de morte em mulheres. No Maranhão, estudos sobre predisposição genética são necessários para investigar os índices de incidência e mortalidade. Avaliou-se o câncer familial, a partir dos antecedentes familiares de mulheres falecidas por câncer de m...

  8. Prolonged multifocal electroretinographic implicit times in the ocular ischemic syndrome

    DEFF Research Database (Denmark)

    Kofoed, Peter Kristian; Munch, Inger Christine; Sander, Birgit

    2010-01-01

    Purpose. To examine retinal function in chronic ocular ischemia using multifocal electroretinography (mfERG). Methods. Thirteen patients with unilateral ocular ischemic syndrome (OIS) underwent assessment of ophthalmic systolic blood pressure by ocular pneumoplethysmography, carotid artery patenc...

  9. Intraocular pressure and its correlation with blood gas parameters in crested caracaras (Caracara plancus anesthetized with isoflurane and sevoflurane Pressão intra-ocular e sua correlação com parâmetros hemogasométricos em caracarás (Caracara plancus anestesiados com isofluorano e sevofluorano

    Directory of Open Access Journals (Sweden)

    A.P. Ribeiro

    2008-12-01

    Full Text Available The intraocular pressure (IOP and its correlations with arterial carbon dioxide partial pressure (PaCO2 and arterial pH were studied in five crested caracaras (Caracara plancus anesthetized with isoflurane (ISO and sevoflurane (SEV. Baseline IOP values were measured in both eyes (M0. Brachial artery was previously catheterized to obtain blood gas and cardiorespiratory analysis. Anesthesia was induced with 5% ISO and maintained with 2.5% for 40 minutes. IOP measurements and blood samples were evaluated in different moments until the end of the procedure. After recovering, a second anesthesia was induced with 6% SEV and maintained with 3.5%. Parameters were evaluated at the same time points of the previous procedure. IOP reduced significantly (P= 0.012 from M0 at all time points and no significative changes were observed between ISO and SEV anesthesias. Correlation between IOP and PaCO2 and between PIO and blood pH were found only for SEV. IOP and blood pH decreased in parallel with IOP, whereas values of PaCO2 increased in caracaras anesthetized with isoflurane and sevoflurane.Avaliou-se a pressão intra-ocular (PIO e estimaram-se as correlações entre PIO e pressão de dióxido de carbono (PaCO2 e pH arterial de cinco caracarás (Caracara plancus, anestesiados com isofluorano (ISO ou sevofluorano (SEV. Valores basais da PIO foram aferidos em ambos os olhos (M0. Cateterizou-se previamente a artéria braquial para obtenção de parâmetros hemogasométricos e cardiorrespiratórios. Anestesia foi induzida com ISO a 5V% e mantida por 40 minutos com 2,5V%. PIO e amostras de sangue foram avaliadas em diferentes momentos até o final do procedimento. Após recuperação, uma segunda anestesia foi realizada com SEV a 6% e mantida com 3,5%. Os parâmetros foram aferidos nos mesmos momentos estabelecidos previamente. A PIO decresceu significativamente (P=0,012 de M0 em todos os momentos e não houve diferença estatística entre ISO e SEV. Correla

  10. Ocular perfusion pressure and ocular blood flow in glaucoma.

    Science.gov (United States)

    Cherecheanu, A Popa; Garhofer, G; Schmidl, D; Werkmeister, R; Schmetterer, L

    2013-02-01

    Glaucoma is a progressive optic neuropathy of unknown origin. It has been hypothesized that a vascular component is involved in glaucoma pathophysiology. This hypothesis has gained support from studies showing that reduced ocular perfusion pressure is a risk factor for the disease. The exact nature of the involvement is, however, still a matter of debate. Based on recent evidence we propose a model including primary and secondary insults in glaucoma. The primary insult appears to happen at the optic nerve head. Increased intraocular pressure and ischemia at the post-laminar optic nerve head affects retinal ganglion cell axons. Modulating factors are the biomechanical properties of the tissues and cerebrospinal fluid pressure. After this primary insult retinal ganglion cells function at a reduced energy level and are sensitive to secondary insults. These secondary insults may happen if ocular perfusion pressure falls below the lower limit of autoregulation or if neurovascular coupling fails. Evidence for both faulty autoregulation and reduced hyperemic response to neuronal stimulation has been provided in glaucoma patients. The mechanisms appear to involve vascular endothelial dysfunction and impaired astrocyte-vessel signaling. A more detailed understanding of these pathways is required to direct neuroprotective strategies via the neurovascular pathway. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. Membrana amniótica nas cirurgias reconstrutivas da superfície ocular nas ceratoconjuntivites cicatriciais Amniotic membrane for ocular surface reconstruction in cicatricial keratoconjunctivitis

    Directory of Open Access Journals (Sweden)

    José Alvaro Pereira Gomes

    1999-10-01

    Full Text Available Objetivo: A membrana amniótica tem se consolidado como útil adjuvante no tratamento de afecções da superfície ocular. Sua utilização baseia-se na capacidade de beneficiar o processo de epitelização, além de reduzir os processos inflamatório, angiogênico e cicatricial. O objetivo deste trabalho foi investigar a utilização da membrana amniótica como adjuvante no tratamento das ceratoconjuntivites cicatriciais. Métodos: A membrana amniótica foi captada a partir de parto cesárea e conservada em meio de preservação de córnea e glicerol 1:1 e conservada à -80ºC. Onze olhos de 10 pacientes portadores de ceratoconjuntivite cicatricial grave foram submetidos à cirurgia reconstrutiva da superfície ocular empregando membrana amniótica associada (8 casos ou não (3 casos a transplante de limbo e conjuntiva. Dos 10 pacientes, 3 tinham diagnóstico de síndrome de Stevens-Johnson (SSJ (4 olhos, 6 queimadura ocular por álcali (6 olhos e 1 trauma mecânico (1 olho. Resultados: O tempo médio de seguimento foi de 5,22 meses (variação entre 2 e 13 meses. Um caso de SSJ apresentou infecção pós-operatória e foi excluído da análise dos resultados. Dos outros 10 casos, obtivemos êxito na reconstrução da superfície ocular em 8 casos (80%. Insucesso foi observado em 2 casos de SSJ que apresentavam necrose de córnea no momento da cirurgia (20%. Em relação à acuidade visual, observamos que todos os pacientes apresentaram melhora ou manutenção da acuidade visual. Conclusões: O uso de membrana amniótica constitui uma opção alternativa de grande utilidade na reconstrução da superfície ocular dos casos graves de ceratoconjuntivites cicatriciais que não estejam apresentando necrose estromal. Estudos com maior casuística e tempo de seguimento são necessários para melhor avaliar esse procedimento.Purpose: Amniotic membrane has been consolidated as an useful adjunct in the treatment of ocular surface disorders. Its use is

  12. Ocular associations of metabolic syndrome

    Directory of Open Access Journals (Sweden)

    Rupali Chopra

    2012-01-01

    Full Text Available Metabolic syndrome is a cluster of diseases including central obesity, dyslipidemia, hyperglycemia, and high blood pressure. People with metabolic syndrome have been shown to be at an increased risk of developing cardiovascular disease, beyond the risk associated with individual components of the syndrome. The association of diabetes and hypertension with retinopathy, cataract, and raised intraocular pressure is well known. This review highlights the association of metabolic syndrome, including all its components, with various ocular conditions such as retinopathy, central retinal artery occlusion, cataracts, and raised intraocular pressure.

  13. Raman Spectroscopy of Ocular Tissue

    Science.gov (United States)

    Ermakov, Igor V.; Sharifzadeh, Mohsen; Gellermann, Warner

    The optically transparent nature of the human eye has motivated numerous Raman studies aimed at the non-invasive optical probing of ocular tissue components critical to healthy vision. Investigations include the qualitative and quantitative detection of tissue-specific molecular constituents, compositional changes occurring with development of ocular pathology, and the detection and tracking of ocular drugs and nutritional supplements. Motivated by a better understanding of the molecular mechanisms leading to cataract formation in the aging human lens, a great deal of work has centered on the Raman detection of proteins and water content in the lens. Several protein groups and the hydroxyl response are readily detectable. Changes of protein compositions can be studied in excised noncataractous tissue versus aged tissue preparations as well as in tissue samples with artificially induced cataracts. Most of these studies are carried out in vitro using suitable animal models and conventional Raman techniques. Tissue water content plays an important role in optimum light transmission of the outermost transparent ocular structure, the cornea. Using confocal Raman spectroscopy techniques, it has been possible to non-invasively measure the water to protein ratio as a measure of hydration status and to track drug-induced changes of the hydration levels in the rabbit cornea at various depths. The aqueous humor, normally supplying nutrients to cornea and lens, has an advantageous anterior location for Raman studies. Increasing efforts are pursued to non-invasively detect the presence of glucose and therapeutic concentrations of antibiotic drugs in this medium. In retinal tissue, Raman spectroscopy proves to be an important tool for research into the causes of macular degeneration, the leading cause of irreversible vision disorders and blindness in the elderly. It has been possible to detect the spectral features of advanced glycation and advanced lipooxydation end products in

  14. Miasis ocular por Oestrus ovis

    Directory of Open Access Journals (Sweden)

    María Beltrán F

    2006-01-01

    Full Text Available Se presentan tres casos de miasis ocular (dos adultos y un niñoprocedentes de zonas ganaderas de la provincia de Huaura,departamento de Lima,que acudieron al Hospital Regional de Huacho por presentar el ojo rojo,fotofobia, edema palpebral y sensación de cuerpo extraño;se extrajeron larvas adheridas al canto interno del ojo,las cuales se recibieron en el Instituto Nacional de Salud y fueron identificadas como Oestrus ovis .

  15. Reabilitação visual com lentes de contato após trauma ocular Visual rehabilitation with contact lenses after ocular trauma

    Directory of Open Access Journals (Sweden)

    Adamo Lui Netto

    2008-12-01

    Full Text Available Trauma ocular é causa importante de baixa de acuidade visual em todos os países do mundo. A integridade do bulbo ocular é primordial para recuperação visual nesses pacientes. Acidentes domésticos, automobilísticos, esportivos, além de queimaduras químicas e térmicas são as principais causas de trauma em nosso meio. O uso de lentes de contato é indicado para a reabilitação visual em casos de astigmatismos regulares ou irregulares de córnea, anisometropias, afacias, opacidades paracentrais superficiais ou profundas na córnea decorrentes do trauma ocular. As lentes de contato podem ser utilizadas no pós-trauma com finalidade terapêutica ou para correção visual. As lentes mais utilizadas para correção visual pós-trauma são as lentes de contato rígidas gás permeáveis, com alto coeficiente de permeabilidade. As lentes de contato gelatinosas podem ser usadas imediatamente após o trauma ocular com finalidade terapêutica e mais tardiamente para correção óptica em afacias e anisometropias traumáticas. A lente de contato é parte importante no tratamento tardio do trauma ocular, propiciando melhora significativa da acuidade visual na maioria dos casos.Ocular trauma is an important cause of visual acuity loss worldwide. Visual recovery is related to anatomical integrity. The main causes of trauma are domestic and automobilist accidents, sports practice and chemical or thermic burns. Contact lens is indicated for visual rehabilitation in cases of corneal regular and irregular astigmatisms, anisometropic and aphakic patients and in cases of deep or superficial corneal opacities that do not affect the visual axis. Contact lens can be used in the post- trauma period for therapeutic and optical purposes. Rigid gas permeable contact lens, with a high permeability index, is the most used for optical purpose. Soft contact lens can be used immediately after trauma as therapy or later for optical correction in aphakic and

  16. Queimaduras oculares químicas: epidemiologia e terapêutica Chemical burns of the eye: epidemiology and treatment

    Directory of Open Access Journals (Sweden)

    Luciana da Cruz Noia

    2000-10-01

    Full Text Available Introdução: Queimaduras oculares químicas podem produzir danos importantes à superfície ocular, resultando em incapacidade visual transitória ou permanente. Objetivos: Levantar dados acerca da epidemiologia e do tratamento inicial aplicado aos pacientes vítimas de queimaduras oculares químicas que chegam a um hospital-escola. Métodos: Foi realizado exame oftalmológico em 47 pacientes vítimas de queimaduras oculares químicas no pronto- socorro do Hospital São Paulo - Escola Paulista de Medicina / Universidade Federal de São Paulo. Resultados: A maioria das vítimas era de jovens do sexo masculino e acidentes de trabalho foram bastante freqüentes (46,8%. Agentes de natureza básica (alcalina foram envolvidos em 55,32% dos casos. A córnea foi afetada em 95,7% dos casos. Os graus I (78,8% e II (12,8% da classificação de Hughes foram os mais observados. O tratamento inicial dos pacientes foi realizado em 89,4% dos casos (irrigação copiosa do olho afetado com solução salina e remoção de debris e 21 (44,68% casos receberam medicações tópicas. Conclusões: Foram observados vários erros na abordagem inicial dos pacientes, o que pode ter influenciado o prognóstico de alguns pacientes.Purpose: Chemical injuries of the eye may produce exten-sive damage to the ocular surface, resulting in transient or per-manent visual impairment. Purposes: To obtain data about epidemiology and inicial treatment aplied to patients who have suffered from ocular chemical burns and have arrived at a universitary hospital. Methods: An ocular evaluation was performed 47 patients with ocular chemical burns in the ophthalmological emer-gency room of the Hospital São Paulo -- Escola Paulista de Medicina / Universidade Federal de São Paulo. Results: Most victims were young male adults and industrial accidents were quite frequent (46.8%. Alkaline agents were more often involved (55.32%. The cornea was affected in 95.7% of the cases and grade I and II of

  17. Correlation between clinical diagnosis and PCR analysis of serum, aqueous, and vitreous samples in patients with inflammatory eye disease Correlação entre o diagnóstico clínico e análise do PCR de amostras do soro, aquoso e vítreo em pacientes com doença inflamatória ocular

    Directory of Open Access Journals (Sweden)

    Kimble Matos

    2007-02-01

    (especificidade, sensibilidade do teste da reação da cadeia de polimerase (PCR na detecção de citomegalovírus (CMV, herpes vírus e varicela zoster (HSV, VZV, Epstein-Barr vírus (EBV, Mycobacterium sp e Toxoplasma gondii no diagnóstico de pacientes com ou sem AIDS, com uveíte infecciosa presumível, utilizando amostras de humor aquoso, humor vítreo e soro. MÉTODOS: Vinte pacientes com uveíte infecciosa presumível foram estudados. Dezesseis destes apresentavam AIDS e quatro eram imunocompetentes. Foram utilizados quatro pacientes como grupo controle que se submeteram a vitrectomia. A avaliação clínica foi feita conjuntamente com três oftalmologistas. O exame do PCR do soro, aquoso e vítreo foi feito sem o conhecimento da hipótese diagnóstica pela equipe do laboratório. RESULTADOS: Doze pacientes tinham o diagnóstico clínico de retinite por CMV. Deste subgrupo 6 (50% eram PCR positivo para CMV no vítreo, 3 (25% eram PCR positivos para CMV no soro e nenhum destes foi positivo no aquoso. Cinco pacientes tinham o diagnóstico clínico de necrose aguda de retina (ARN. Três (60% destes eram PCR positivos para HSV/VZV no vítreo. Um destes pacientes era PCR positivo tanto para EBV e HSV/VZV na amostra do vítreo. Um destes pacientes com herpes zoster cutâneo era PCR positivo para HSV/VZV no soro. Quatro pacientes tinham o diagnóstico de toxoplasmose ocular presumida, um paciente (25% era PCR positivo para Toxoplasma gondii no soro, 3 (75% eram positivos no aquoso e 2 (50% eram positivo no vítreo. Um paciente com tuberculose ocular presumível era PCR positivo tanto no soro quanto no vítreo. Nenhum dos pacientes do grupo controle era PCR positivo em qualquer amostra. CONCLUSÃO: O exame do PCR é procedimento diagnóstico auxiliar que deve ser utilizado conjuntamente com os aspectos clínicos.

  18. Estudo do segmento anterior com a câmera rotatória de Scheimpflug em pacientes candidatos à cirurgia refrativa Anterior ocular segment study with the Scheimpflug rotational camera in refractive surgery candidates

    Directory of Open Access Journals (Sweden)

    Celina Murata

    2007-08-01

    Full Text Available OBJETIVO: Analisar o segmento anterior com aparelho de câmera rotatória de Scheimpflug (Pentacam® em candidatos à cirurgia refrativa, estabelecendo o padrão de variabilidade do volume corneano, do volume e da profundidade da câmara anterior e da paquimetria óptica nesta população. MÉTODOS: Estudo retrospectivo de 297 olhos (149 pacientes que foram examinados com Pentacam®. Os pacientes foram divididos conforme o equivalente esférico em míopes (n=242 olhos e hipermétropes (n=55 olhos para analisar o volume corneano, o volume e a profundidade da câmara anterior e a paquimetria óptica. RESULTADOS: No grupo dos míopes, a média do volume corneano total foi de 59,37 ± 3,51 mm³; do volume nos 3 mm de 3,87 ± 0,23 mm³, nos 5 mm de 11,31 ± 0,67 mm³, e nos 7mm de 24,30 ± 1,43 mm³; do volume da câmara anterior 198,74 ± 32,40 mm³; da profundidade da câmara anterior 3,19 ± 0,28 mm e da paquimetria óptica 533,33 ± 33,47 mm. No grupo dos hipermétropes, a média do volume corneano total foi de 60,77 ± 3,31 mm³, do volume nos 3 mm de 4,01 ± 0,20 mm³, nos 5 mm de 11,73 ± 0,58 mm³, e nos 7 mm de 25,09 ± 1,21 mm³; do volume da câmara anterior 146,61 ± 32,86 mm³; da profundidade da câmara anterior 2,76 ± 0,38 mm e da paquimetria de 550,52 ± 29,49 mm. A diferença entre os grupos foi significativa para todas as variáveis (pPURPOSE: To analyze the anterior segment of refractive surgery candidates and establish the variability pattern in this population regarding corneal volume, anterior chamber volume and depth and corneal thickness, using the noncontact three dimensional analyzer Pentacam®. METHODS: A retrospective study of 297 eyes of 149 patients was conducted using Pentacam®. According to the spherical equivalent value two groups were created, myopia (n=242 eyes and hyperopia (n=55 eyes, to analyze the variables of corneal volume, anterior chamber volume and depth and corneal thickness. RESULTS: The mean values of

  19. Ocular trauma | Mustak | South African Family Practice

    African Journals Online (AJOL)

    Ocular trauma is an important cause of unilateral blindness and visual impairment across the world. Most injuries are accidental, work-related injuries in developed countries, while assaults predominate as a cause in developing countries. Trauma may result in various forms of ocular injuries, ranging from minor insult to ...

  20. Ocular changes in pregnant Nigerian women

    African Journals Online (AJOL)

    2011-05-06

    May 6, 2011 ... Objective: Pregnancy results in a lot of hormonal changes in the body and the eyes are no exception. These ocular changes could be physiologic, pathologic or a modification of a pre-existing condition. The aim of this study was to determine physiologic ocular changes that are associated with pregnancy in ...

  1. Ocular manifestation of granulomatosis with polyangitis

    Directory of Open Access Journals (Sweden)

    Mary Grace

    2015-01-01

    Full Text Available Ocular manifestation of granulomatosis with polyangitis. Proptosis is the most common ocular manifestation of granulomatosis with polyangitis. It is due to inflammation of the extraocular muscles or vasculitis of the vas nervosum. It is a poor prognostic sign.

  2. Ocular abnormalities in Floating-Harbor syndrome.

    Science.gov (United States)

    Asseidat, Ibrahim; Kaufman, Lawrence M

    2009-04-01

    We present the first case report of a comprehensive eye examination in a patient with Floating-Harbor syndrome. Ocular findings were limited to partially accommodative, acquired esotropia, and unusual eyelashes. A variety of other ocular features have been previously reported in the nonophthalmic medical literature and are herein reviewed.

  3. OCULAR FINDINGS IN CHILDREN WITH CEREBRAL PALSY ...

    African Journals Online (AJOL)

    Cerebral palsy is commonly associated with ocular abnormalities which often impact on their development and education. There is paucity of studies on this in Nigeria. We decided to study/ determine the prevalence of ocular abnormalities among children with cerebral palsy that attended the neurology clinic of University of ...

  4. Ocular findings following trauma from paintball sports.

    Science.gov (United States)

    Taban, M; Taban, M; Sears, J E

    2008-07-01

    To raise awareness of potential significant ocular damage and visual loss secondary to paintballs in those not wearing ocular protection and to report high incidence of chorioretinitis sclopetaria from paintball contusion. We reviewed cases of eye injury presenting to a single institution from 2000 to 2005. Those cases in which the injury was attributed to paintballs were identified and evaluated to determine ocular findings and visual prognosis. Ocular paintball injuries occurred in eight male subjects and one female subject (nine eyes) with an average age of 16 years (range, 11-26). None had ocular protection at the time of ocular injury. On initial examination, vitreous haemorrhage was present in six eyes (67%), maculopathy, hyphema, cataract, and commotio retinae were each present in four eyes (44%). Two eyes suffered retinal detachment and one eye an optic nerve avulsion. Chorioretinitis sclopetaria occurred in four eyes (44%). The final visual acuity was > or =20/40 in three eyes, 20/50 to 20/150 in two eyes, and paintballs can result in severe ocular damage and visual loss. Increased awareness and need for proper ocular protection should be emphasized by ophthalmologists. Chorioretinitis sclopetaria occurs with a high frequency and its presence should be recognized, as its management is different from retinal tear or detachment.

  5. Estudo sobre a aplicabilidade de adesivos biológicos à reinserção de músculo ocular externo em coelhos - I Experimento I - Medidas dos tempos dos procedimentos, das forças de adesão mioescleral e estudos clínico e histopatológico A study of the applicability of biological adhesives to the reinsertion of an external ocular muscle in rabbits - I Experiment I - Measurements of duration of procedures, and clinical and histopathologic studies

    Directory of Open Access Journals (Sweden)

    Beatriz Simões Corrêa

    2005-10-01

    Full Text Available OBJETIVO: Medir o tempo da operação, as forças de adesão tecidual e fazer estudo clínico e histopatológico de reinserções oculares de retos superiores de coelho com quatro diferentes adesivos teciduais, como alternativa à utilização de sutura de poliglactina em operações de estrabismo. MÉTODOS: Cem coelhos da raça Nova Zelândia foram distribuídos em dois experimentos, I-A e I-B, de cinqüenta coelhos cada, e estes em cinco grupos de dez coelhos (vinte olhos, submetidos à operação de desinserção do músculo reto superior de ambos os olhos, e reinserção com sutura (controle com poliglactina 910, 6-0 ou adesivos teciduais, de fibrina, cianoacrilato, albumina-glutaraldeído e gelatina-resorcinol-formaldeído-glutaraldeído. Os coelhos do experimento I-A foram submetidos à dinamometria nos dez minutos após o reposicionamento muscular. Os coelhos do experimento I-B foram submetidos à avaliação clínica e histopatológica. RESULTADOS: Verificou-se melhor desempenho dos adesivos teciduais no tempo gasto para realizar a operação. Quanto à força de adesão, nenhum dos adesivos apresentou 100% de casos com resistência à tensão igual ou maior que 100 gf. Com relação às avaliações clínica e histopatológica, quanto à presença dos sinais inflamatórios e suas intensidades o adesivo fibrínico utilizado neste trabalho apresentou melhor desempenho do que a sutura de poliglactina 910, tendo os demais adesivos apresentado resultados piores, quando comparados aos do grupo controle (sutura. CONCLUSÃO: Os adesivos estudados mostraram-se inadequados para as operações de estrabismo.PURPOSE: To measure the duration of the operation, the strength of tissue adhesion, and to perform a clinical and histopathological study of ocular reinsertion of superior rectus muscles of rabbits with four different tissue adhesives, as an alternative to the use of polyglactin suture in strabismus surgeries. METHODS: One hundred New Zealand

  6. Correção das aberrações oculares nos retratamentos de LASIK personalizado e convencional Correction of ocular aberrations in custom and standard LASIK retreatments

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    Andréia Peltier Urbano

    2009-10-01

    Full Text Available OBJETIVO: Comparar a correção das aberrações oculares nos retratamentos de LASIK personalizado e convencional. MÉTODOS: Foi realizado um estudo prospectivo, randomizado, de 74 olhos de 37 pacientes submetidos ao retratamento de LASIK para correção de miopia e astigmatismo. Cada paciente foi submetido ao retratamento de LASIK personalizado Zyoptix (Bausch & Lomb em um olho e convencional Planoscan (Bausch & Lomb no olho contralateral. Foi comparada a correção das aberrações oculares nos retratamentos personalizado e convencional. RESULTADOS: No sexto mês pós-operatório, os olhos submetidos ao retratamento Zyoptix apresentaram diminuição estatisticamente significativa do defocus, astigmatismo, coma, aberração esférica, segunda ordem, terceira ordem, alta ordem e aberrações totais. Os olhos submetidos ao retratamento Planoscan apresentaram diminuição estatisticamente significativa do defocus, segunda ordem e aberrações totais. CONCLUSÕES: O retratamento personalizado foi superior ao retratamento convencional para a correção das aberrações oculares de baixa e alta ordens.PURPOSE: To compare the correction of ocular aberrations between custom and standard LASIK retreatment. METHODS: Prospective, randomized trial with paired eye control of 74 eyes from 37 patients who underwent LASIK retreatment. Each patient underwent retreatment using Zyoptix LASIK (Bausch & Lomb in 1 eye and Planoscan LASIK (Bausch & Lomb in the fellow eye. Correction of ocular aberrations was compared between custom and standard LASIK retreatments. RESULTS: At 6 months, there was a statistically significant reduction in defocus, astigmatism, coma, spherical aberration, second, third, higher-order and total aberration in Zyoptix eyes. There was a statistically significant reduction in defocus, second-order and total aberration in Planoscan eyes. CONCLUSIONS: Custom retreatment was statistically superior than standard retreatment for correction of lower

  7. Imaging the ocular motor nerves

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, Teresa [Department of Radiology, Leiden University Medical Center (Netherlands)], E-mail: T.A.Ferreira@lumc.nl; Verbist, Berit [Department of Radiology, Leiden University Medical Center (Netherlands)], E-mail: B.M.Verbist@lumc.nl; Buchem, Mark van [Department of Radiology, Leiden University Medical Center (Netherlands)], E-mail: M.A.van_Buchem@lumc.nl; Osch, Thijs van [C.J. Gorter for High-Field MRI, Department of Radiology, Leiden University Medical Center (Netherlands)], E-mail: M.J.P.van_Osch@lumc.nl; Webb, Andrew [C.J. Gorter for High-Field MRI, Department of Radiology, Leiden University Medical Center (Netherlands)], E-mail: A.Webb@lumc.nl

    2010-05-15

    The ocular motor nerves (OMNs) comprise the oculomotor, trochlear and the abducens nerves. According to their course, they are divided into four or five anatomic segments: intra-axial, cisternal, cavernous and intra-orbital and, for the abducens nerve, an additional interdural segment. Magnetic resonance imaging is the imaging method of choice in the evaluation of the normal and pathologic ocular motor nerves. CT still plays a limited but important role in the evaluation of the intraosseous portions at the skull base and bony foramina. We describe for each segment of these cranial nerves, the normal anatomy, the most appropriate image sequences and planes, their imaging appearance and pathologic conditions. Magnetic resonance imaging with high magnetic fields is a developing and promising technique. We describe our initial experience with a Phillips 7.0 T MRI scanner in the evaluation of the brainstem segments of the OMNs. As imaging becomes more refined, an understanding of the detailed anatomy is increasingly necessary, as the demand on radiology to diagnose smaller lesions also increases.

  8. Ocular Surface Reconstruction: Recent Innovations

    Directory of Open Access Journals (Sweden)

    Madhavan HN

    2009-01-01

    Full Text Available The ocular surface is exceptionally rich in complexity and functionality. Severe ocular surface disorders/conditions, such as chemical or thermal injuries, Stevens-Johnson syndrome (SJS, ocular cicatricial pemphigoid, neurotrophic keratopathy, chronic limbitis, and severe microbial keratitis cause significant morbidities and even corneal blindness. Hypofunction may be caused by Aniridia, Neurotrophy, Endocrine, Pterygium and Chronic limbitis Approximately 6000 patients are seen in Ocular Surface Clinic every year; almost 80% have some form of dry eyes. About 125 new patients of Stevens Johnson Syndrome are seen in a year of which approximately 25% may benefit from Cultured Epithelial Transplant and 75 new patients of thermal/chemical injury in a year of which almost 80% will benefit from Stem Cell Transplantation. Of the 128 severe vernal keratoconjunctivitis which were seen in the ocular surface clinic, 10% require stem cell transplantation. Nearly 30 new cases of Ocular cicatrical pemphigoid every year are seen and they may need stem cell transplantation. In addition, several patients with persistent epithelial defects may benefit from limbal stem cell transplantation to alleviate, maintain conjunctivalization regression and corneal avascularity limbal deficiency, and restore vision. Even if granted that this statistics is for a single large ophthalmic hospital, for a large country as India with 1.1 billion populations, the number of patients requiring corneal stem cell transplantation is enormous. Stem cells in the palisades of Vogt participate in regeneration and preservation of corneal transparency and avascularity. The diminished regenerative capacity seen in LSCD is characterized by persistent epithelial defects, erosion and ulceration, conjunctivalization and neovascularization, and chronic inflammation. Standard corneal transplantation for restoration of corneal clarity and avascularity is a contraindication in the surgical management

  9. Influence of refractive correction on ocular dominance

    Science.gov (United States)

    Nakayama, Nanami; Kawamorita, Takushi; Uozato, Hiroshi

    2010-07-01

    We investigated the effects of refractive correction and refractive defocus on the assessment of sensory ocular dominance. In 25 healthy subjects (4 males and 21 females) aged between 20 and 31 years, a quantitative measurement of sensory ocular dominance was performed with refractive correction and the addition of a positive lens on the dominant eye. Sensory ocular dominance was measured with a chart using binocular rivalry targets. The reversal point changed after the addition of a +1.00 D lens on the dominant eye in all subjects. However, sighting ocular dominance and stereopsis did not change after the addition of a positive lens on the dominant eye ( P > 0:05, Wilcoxon test). These results suggest that refractive correction affects sensory ocular dominance, indicating the possible development of a new type of occlusion for amblyopia in the future.

  10. Anterior Segment Imaging in Combat Ocular Trauma

    Directory of Open Access Journals (Sweden)

    Denise S. Ryan

    2013-01-01

    Full Text Available Purpose. To evaluate the use of ocular imaging to enhance management and diagnosis of war-related anterior segment ocular injuries. Methods. This study was a prospective observational case series from an ongoing IRB-approved combat ocular trauma tracking study. Subjects with anterior segment ocular injury were imaged, when possible, using anterior segment optical coherence tomography (AS-OCT, confocal microscopy (CM, and slit lamp biomicroscopy. Results. Images captured from participants with combat ocular trauma on different systems provided comprehensive and alternate views of anterior segment injury to investigators. Conclusion. In combat-related trauma of the anterior segment, adjunct image acquisition enhances slit lamp examination and enables real time In vivo observation of the cornea facilitating injury characterization, progression, and management.

  11. Recent advances on ocular Demodex infestation.

    Science.gov (United States)

    Cheng, Anny M S; Sheha, Hosam; Tseng, Scheffer C G

    2015-07-01

    To summarize recent advances on ocular Demodex infestation. Demodex infestation is a potential cause of ocular surface inflammation. The pathogenesis of Demodex in eliciting ocular surface inflammation has been further clarified. Cliradex is currently the treatment of choice, it comprises the most active ingredient of tea tree oil, that is terpinen-4-ol, which helps eradicate Demodex mites and reduce ocular surface inflammation. Ocular demodicosis is a common but overlooked eye disease that manifests a number of morbidities. Demodex folliculorum causes chronic anterior blepharitis whereas Demodex brevis causes posterior blepharitis, meibomian gland dysfunction, recurrent chalazia, and refractory keratoconjunctivitis. The lash sampling and microscopic counting method and in-vivo confocal microscopy are key diagnostic methods. Cliradex shows promising potential to reduce Demodex counts with additional antibacterial, antifungal, and anti-inflammatory actions.

  12. Clinical and Immunological Responses in Ocular Demodecosis

    Science.gov (United States)

    Kim, Jae Hoon; Chun, Yeoun Sook

    2011-01-01

    The purpose of this study was to investigate clinical and immunological responses to Demodex on the ocular surface. Thirteen eyes in 10 patients with Demodex blepharitis and chronic ocular surface disorders were included in this study and treated by lid scrubbing with tea tree oil for the eradication of Demodex. We evaluated ocular surface manifestations and Demodex counts, and analyzed IL-1β, IL-5, IL-7, IL-12, IL-13, IL-17, granulocyte colony-stimulating factor, and macrophage inflammatory protein-1β in tear samples before and after the treatment. All patients exhibited ocular surface manifestations including corneal nodular opacity, peripheral corneal vascularization, refractory corneal erosion and infiltration, or chronic conjunctival inflammatory signs before treatment. After treatment, Demodex was nearly eradicated, tear concentrations of IL-1β and IL-17 were significantly reduced and substantial clinical improvement was observed in all patients. In conclusion, we believe that Demodex plays an aggravating role in inflammatory ocular surface disorders. PMID:21935281

  13. Adult Ocular Toxocariasis Mimicking Ciliary Body Malignancy

    Directory of Open Access Journals (Sweden)

    Ahmad M. Mansour

    2014-01-01

    Full Text Available Purpose. To discuss an unusual presentation of ocular toxocariasis. Methods. Case report. Results. A 40-year-old woman presented with decreased vision in the left eye with a long history of recurrent red eye from uveitis. Eosinophilia and positive ELISA titers for Toxocara canis favored the diagnosis of ocular toxocariasis. Over 3 months, an anterior scleral mass had a rapid growth raising the possibility of medulloepithelioma, which rarely can mimic uveitic syndromes. Surgical plan changed from local excision to enucleation. Histopathology demonstrated a large homogeneous mass of chronic inflammatory cells with inflammation of the overlying thinned out sclera, medial rectus insertion, and limbal cornea. The triad of peripheral granuloma, eosinophilia, and positive blood serology established the diagnosis of ocular toxocariasis. Conclusions. Ocular toxocariasis can mimic ocular malignancy such as medulloepithelioma in adults and rarely presents as an anterior scleral mass.

  14. Pediatric ocular nanomedicines: Challenges and opportunities.

    Science.gov (United States)

    Sheybani, Natasha D; Yang, Hu

    2017-09-01

    The eye is a highly complex, yet readily accessible organ within the human body. As such, the eye is an appealing candidate target for a vast array of drug therapies. Despite advances in ocular drug therapy research, the focus on pediatric ocular drug delivery continues to be highly underrepresented due to the limited number of degenerative ocular diseases with childhood onset. In this review, we explore more deeply the reasons underlying the disparity between ocular therapies available for children and for adults by highlighting diseases that most commonly afflict children (with focus on the anterior eye) and existing prognoses, recent developments in ocular drug delivery systems and nanomedicines for children, and barriers to use for pediatric patients.

  15. Human ocular Thelaziasis in Karnataka

    Directory of Open Access Journals (Sweden)

    Prabhakar S Krishnachary

    2014-01-01

    Full Text Available Thelaziasis is an Arthropod-born disease of the eye and adnexa caused by Thelazia callipaeda, a nematode parasite transmitted by drosophilid flies to carnivores and humans. Because of its distribution mainly confined to South Asian countries and Russia, it is commonly known as Oriental Eye worm. It is often under-reported and not been given its due clinical importance. We report first case of human Thelaziasis from Hassan District, Karnataka. Five creamy-white, translucent worms were removed from the conjunctival sac of a 74-year-old male patient. Based on morphological characters, the worms were identified as nematodes belonging to the genus Thelazia and speciation was confirmed by CDC, Atlanta as callipaeda. Rarity of the disease and its ability to cause both extra and intraocular manifestations leading to ocular morbidity is the reason for presenting this case. From the available data, this is the first case report from Karnataka, India.

  16. [Ocular manifestations in xeroderma pigmentosum].

    Science.gov (United States)

    Süsskind, D; Berneburg, M; Rohrbach, J M

    2011-03-01

    The aim of this study was to evaluate ocular changes in patients with xeroderma pigmentosum (XP) and Cockayne syndrome (CS). Both diseases belong to the progeroid syndromes caused by single gene mutations with premature aging. Both syndromes are very rare autosomal recessive diseases caused by a gene defect leading to deficient DNA repair. 12 patients (4 female, 8 male) with XP between 3 and 67 years old and a 39-year-old female patient with CS were examined. The examination included visual acuity testing, slit lamp biomicroscopy, funduscopy and performance of a Schirmer test. Changes of the lids in the XP group included blepharitis in 7 patients, distichiasis in 2, and madarosis in 3 patients. 8 patients had multiple lentigines solares of the lids. One patient showed scars of the lower lids after excision of a squamous cell carcinoma and a basal cell carcinoma. Conjunctival lesions comprised a tumour of unknown origin of the conjunctiva in 1 patient, teleangiectasia of the conjunctiva in 5 patients, pterygia in 4, and pinguecula in 1 patient. Two patients had an intraepithelial melanosis of the conjunctiva, and one showed conjunctival nevi. Two patients had corneal scars and corneal vascularisation, another a significant conjunctivalisation of the cornea. A Schirmer test was feasible only in 3 patients. Tear production was markedly reduced in all these patients. Break-up time was shortened significantly in 6 patients examined. The patient with the CS showed atrophy of the pupillary rim and a subcapsular cataract. Funduscopically there were pigment epithelial changes. Patients with XP often exhibit ocular changes. Beside the light-dependent degenerative and inflammatory manifestations at the lids, the conjunctiva and the cornea patients with XP also develop malignancies early in life. The majority of patients suffer from dry eye symptoms. © Georg Thieme Verlag KG Stuttgart · New York.

  17. Oncologia de Cabeça e Pescoço: enquadramento epidemiológico e clínico na avaliação da Qualidade de Vida Relacionada com a Saúde Head and Neck Cancer: Health Related Quality of Life Assessment considering clinical and epidemiological perspectives

    Directory of Open Access Journals (Sweden)

    Augusta Silveira

    2012-03-01

    Full Text Available A importância das doenças oncológicas como causa de morbilidade e mortalidade está em crescimento, sendo reconhecido o seu impacto social e peso global pelos custos económicos e sociais envolvidos na sua prevenção, tratamento e reabilitação. As patologias oncológicas de cabeça e pescoço representam um dos seis tumores malignos mais prevalentes em todo o mundo, com um valor estimado de 900.000 novos casos diagnosticados anualmente em escala mundial. Estes doentes oncológicos apresentam deterioração de funções básicas que, quando percepcionadas, têm impacto negativo na sua Qualidade de Vida. Um registo oncológico adequado permite uma análise mais rigorosa dos resultados obtidos na avaliação da Qualidade de Vida Relacionada com a Saúde. Este estudo incluiu 380 doentes oncológicos de cabeça e pescoço e demonstra que as mulheres apresentam resultados de Qualidade de Vida globalmente inferiores. Salienta-se ainda a importância do diagnóstico precoce em oncologia, que se relaciona frequentemente com melhores scores e conclui-se que a localização do tumor tem impacto sobre a autopercepção de Qualidade de Vida. Os valores de Qualidade de Vida Relacionada com a Saúde devem ser interpretados à luz das variáveis sociodemográficas e clínicas, para melhor se avaliar a Patologia Oncológica de Cabeça e Pescoço numa perspectiva epidemiológica no sentido de melhor compreender o processo saúde - doença.The importance of oncology diseases as a cause of morbidity and mortality is increasing worldwide, and their social impact is being recognized due to economic and social costs involved in prevention, treatment and rehabilitation. Head and neck cancer is one of the six most prevalent neoplasms worldwide, with an estimated 900,000 new cases diagnosed annually. Regardless of tumor site, deterioration of basic functions affecting head and neck areas are perceived and affect patients' lives. Appropriate cancer registration may

  18. Ocular Dominance and Handedness in Golf Putting.

    Science.gov (United States)

    Dalton, Kristine; Guillon, Michel; Naroo, Shehzad A

    2015-10-01

    In golf, the impact of eye-hand dominance on putting performance has long been debated. Eye-hand dominance is thought to impact how golfers judge the alignment of the ball with the target and the club with the ball, as well as how golfers visualize the line of the putt when making decisions about the force needed to hit the ball. Previous studies have all measured ocular dominance in primary gaze only, despite golfers spending a significant amount of their time in a putting stance (bent at the hips, head tilted down). Thus, the purpose of this study was to assess ocular dominance in both primary gaze (aligning the ball with the target) and putting gaze (addressing the ball and aligning the club). This study investigated measuring pointing ocular dominance in both primary and putting gaze positions on 31 golfers (14 amateur, 7 club professionals, and 10 top professionals). All players were right-handed golfers, although one reported having no hand dominance and one reported being strongly left hand dominant. The results showed that (1) primary and putting gaze ocular dominances are not equal, nor are they predictive of each other; (2) the magnitude of putting ocular dominance is significantly less than the magnitude of primary gaze ocular dominance; (3) ocular dominance is not correlated with handedness in either primary or putting gaze; and (4) eye-hand dominance is not associated with increased putting skill, although ocular dominance may be associated with increased putting success. It is important that coaches assess golfers' ocular dominance in both primary and putting gaze positions to ensure they have the most accurate information upon which to base their vision strategy decisions.

  19. Ocular abnormalities in healthy Standardbred foals.

    Science.gov (United States)

    Barsotti, Giovanni; Sgorbini, Micaela; Marmorini, Paola; Corazza, Michele

    2013-07-01

    To determine the prevalence and describe ocular abnormalities in healthy Standardbred foals within 48 h of birth. One hundred and two neonatal foals. All foals had an unassisted delivery. On the basis of physical examination and the results of hematological and biochemical parameters, all foals were unaffected by systemic diseases. A complete ophthalmic examination was performed within 48 h of birth. Foals with ocular hemorrhages were re-examined weekly until the abnormalities were resolved. 65/102 (63.7%) foals did not show ocular abnormalities, while in 37/102 (36.3%) cases, ocular abnormalities were present. Retinal and subconjunctival hemorrhages were recorded in 19/102 (18.6%), and in 13/102 (12.7%), respectively. In 4/102 (3.9%) animals, an entropion of the lower eyelid was present. Only one foal (1%) showed a congenital nuclear unilateral cataract. No other ocular abnormalities were detected. However, all foals showed various degrees of remnants of hyaloid system. One week after the first ocular examination, retinal hemorrhages had resolved in 100% of the eyes, whereas subconjunctival hemorrhages had disappeared in all eyes by the second week following the first examination. The acquired ocular lesions observed with relatively high frequency in the examined healthy Standardbred foals were ocular hemorrhages, which always showed a good outcome. Although these abnormalities were present at birth, they were not considered strictly congenital but likely acquired during parturition. Instead, congenital ocular abnormalities were rarely diagnosed, and the entropion of the lower eyelid was the most common disease in the breed. © 2012 American College of Veterinary Ophthalmologists.

  20. Refração por retinoscopia com luz em faixa em cães Refraction by streak retinoscopy in dogs

    Directory of Open Access Journals (Sweden)

    J.J.T. Ranzani

    2008-04-01

    Full Text Available A refração ocular por retinoscopia com luz em faixa em 10 cães normais, sem raça definida, demonstrou que a maioria dos animais, independentemente do porte, apresentou tendência à hipermetropia, além de anisometropia e astigmatismo.Ocular refraction by streak retinoscopy performed in 10 mixed breed dogs showed that most of the animals, independently of size, had a tendency to hypermetropia, anisometropia, and astigmatism.

  1. Ocular chemical injuries and their management

    Directory of Open Access Journals (Sweden)

    Parul Singh

    2013-01-01

    Full Text Available Chemical burns represent potentially blinding ocular injuries and constitute a true ocular emergency requiring immediate assessment and initiation of treatment. The majority of victims are young and exposure occurs at home, work place and in association with criminal assaults. Alkali injuries occur more frequently than acid injuries. Chemical injuries of the eye produce extensive damage to the ocular surface epithelium, cornea, anterior segment and limbal stem cells resulting in permanent unilateral or bilateral visual impairment. Emergency management if appropriate may be single most important factor in determining visual outcome. This article reviews the emergency management and newer techniques to improve the prognosis of patients with chemical injuries.

  2. Rotura ocular posterior traumática

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    Laine García Ferrer

    Full Text Available El trauma ocular es una causa importante de morbilidad oftalmológica en el mundo con implicaciones socioeconómicas importantes para el paciente y sus familiares. Ocurre generalmente en adultos jóvenes, con una buena agudeza visual al inicio del evento traumático, la cual se verá comprometida según la severidad del trauma, las estructuras oculares que afecte y las complicaciones que puedan aparecer. Presentamos dos pacientes con rotura escleral posterior secundario a trauma ocular a globo abierto contuso. Se describe el manejo personalizado el seguimiento en cada caso y sus resultados visuales.

  3. Toxocariosis Ocular en Menores de Edad

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    Norma Ocampo

    2001-04-01

    Full Text Available La toxocariosis es una geohelmintiosis producida por la ingestión de
    huevos de Toxocara canis y T. catis, cuyos hospederos definitivos son el perro y el gato. En el humano las larvas producen el Síndrome de Migración Larvaria Visceral y Ocular; en este último produce una enfermedad grave que puede semejar un retinoblastoma (1,2. Los niños son más susceptibles a adquirir esta infección (3. Nuestro objetivo es determinar la frecuencia de toxocariosis ocular en menores de edad con sintomatología ocular.

  4. Ocular flora in adenoviral conjunctivitis

    OpenAIRE

    Nakano, Eliane Mayumi; Freitas, Denise de; Yu, Maria Cecília Zorat; Alvarenga, Lênio Souza; Hofling- Lima, Ana Luisa

    2002-01-01

    Objetivos: Estudar a microbiota aeróbica conjuntival em pacientes com quadro clínico de conjuntivite viral aguda. Método: Trinta pacientes entre 18 e 40 anos portadores de conjuntivite adenoviral e 30 pacientes sem a doença foram submetidos à colheita de material da conjuntiva para cultura. Os portadores de conjuntivite adenoviral foram submetidos ao exame até 3 dias após o início dos sintomas. As culturas foram realizadas utilizando-se os meios de ágar-sangue e ágar-chocolate. Pacientes em u...

  5. Tear Osmolarity and Ocular Surface Parameters as Diagnostic Markers of Ocular Graft-Versus-Host Disease.

    Science.gov (United States)

    Na, Kyung-Sun; Yoo, Young-Sik; Hwang, Kyu-Yeon; Mok, Jee-Won; Joo, Choun-Ki

    2015-07-01

    To evaluate the diagnostic value of tear osmolarity and several ocular surface parameters in screening for ocular surface alterations in ocular graft-vs-host disease (GVHD) patients. Case-control study. Sixty-three patients with ocular GVHD and 74 healthy participants were screened for ocular surface changes using the Ocular Surface Disease Index (OSDI), tear osmolarity, Schirmer test, tear break-up time (TBUT), and fluorescein corneal staining. The severity of ocular GVHD was diagnosed according to the National Institutes of Health (NIH) grading system. The diagnostic sensitivity and specificity and cutoff values were determined for each ocular parameter using a receiver operating characteristic (ROC) curve and area under the curve (AUC) analysis. Significance was defined at P tear osmolarity, corneal staining score, and OSDI score gradually increased as the severity of ocular GVHD increased, and Schirmer value gradually decreased as the GVHD grade increased in severity. The Schirmer test showed greatest diagnostic sensitivity and specificity for ocular GVHD (92.1% sensitivity, 85.7% specificity, cutoff = 9 mm), followed by the TBUT (87.3% sensitivity, 75.0% specificity, cutoff = 6 s), tear osmolarity (98.4% sensitivity, 60.7% specificity, cutoff = 311 mOsm/L), corneal staining score (66.7% sensitivity, 82.1% specificity, cutoff = 2), and OSDI score (77.8% sensitivity, 66.1% specificity, cutoff = 20.8). Multiple diagnostic modalities should be used to detect ocular surface changes in GVHD patients. The severity of ocular GVHD can be effectively monitored using tear osmolarity; however, additional studies are required. Copyright © 2015 Elsevier Inc. All rights reserved.

  6. Análise dos padrões dos movimentos oculares em tarefas de busca visual: efeito da familiaridade e das características físicas do estímulo Analysis of the eye movement patterns in visual search tasks: effect of familiarity and stimulus features

    Directory of Open Access Journals (Sweden)

    Elizeu Coutinho de Macedo

    2007-02-01

    Full Text Available OBJETIVOS: Analisar os movimentos oculares numa tarefa de busca visual assimétrica com letras normais e espelhadas. Explorar o efeito da familiaridade e características do estímulo. MÉTODOS: Oitenta e três universitários emétropes ou com correção óptica foram solicitados a procurar por uma letra normal ou espelhada, num contexto de letras espelhadas ou normais, respectivamente. Foram utilizados quatro tipos de letras (Z, N, E e G e os movimentos dos olhos foram rastreados por meio de um sistema computacional especializado (eyetracking. As medidas utilizadas para análise foram: tempo de reação, duração e número de fixações, duração e distância dos movimentos sacádicos. RESULTADOS: A análise em função do tipo de letra mostrou diferenças para todas as medidas. O tempo de reação, o número de fixações e a distância média dos movimentos sacádicos foram maiores para encontrar uma letra normal em um conjunto de letras espelhadas. A duração média das fixações, entretanto, foi menor nessa situação. Houve interação dupla entre espelhamento e tipo de letra para o tempo de reação, duração média e número de fixações. O tempo de reação e o número de fixações apresentam função crescente de acordo com o grau de complexidade do estímulo, com aumento acentuado na situação em que o alvo é a letra normal. A duração das fixações, por sua vez, diminui em função da complexidade do estímulo e da situação. CONCLUSÕES: Foi mais fácil encontrar uma letra espelhada entre as normais, que o oposto, sendo que o desempenho também sofreu influência do tipo de letra. Quando o contexto é formado por estímulos não familiares e complexos, a duração média das fixações é menor, indicando um processamento visual com amplitude reduzida. Desta forma, são necessárias mais fixações com menor duração para um contexto não familiar e menos fixações com maior duração, para o familiar.PURPOSE: To

  7. Ocular Complications of Diabetes and Therapeutic Approaches

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    Victoria J. Vieira-Potter

    2016-01-01

    Full Text Available Diabetes mellitus (DM is a metabolic disease defined by elevated blood glucose (BG. DM is a global epidemic and the prevalence is anticipated to continue to increase. The ocular complications of DM negatively impact the quality of life and carry an extremely high economic burden. While systemic control of BG can slow the ocular complications they cannot stop them, especially if clinical symptoms are already present. With the advances in biodegradable polymers, implantable ocular devices can slowly release medication to stop, and in some cases reverse, diabetic complications in the eye. In this review we discuss the ocular complications associated with DM, the treatments available with a focus on localized treatments, and what promising treatments are on the horizon.

  8. The pathophysiology of ocular allergy: a review.

    Science.gov (United States)

    Chigbu, De Gaulle I

    2009-02-01

    Allergic eye disease is an abnormal immune hypersensitivity response to allergens. It is characterized by IgE-mediated and/or T-lymphocyte-mediated immune hypersensitivity reactions that lead to an immune response, resulting in the clinical manifestations of ocular allergy. This review will focus on immunopathophysiology of the different types of allergic eye disease commonly encountered in the primary care setting. The objective is to provide the clinician with a considerable understanding of the immunopathogenesis of allergic eye disease. The primary focus of this review will be on the antibody- and cell-mediated immune hypersensitivity reactions relevant to allergic eye disease, the different phases of ocular allergic immune response and the histopathological manifestations of these commonly encountered ocular allergies. The basic concepts of immunology with emphasis on adaptive immunity and lymphocyte activation, as well as the components of the immune system that are relevant to ocular allergy will also be reviewed.

  9. [Ocular toxoplasmosis and consecutive complicated cataract].

    Science.gov (United States)

    Corbu, Cătălina; Creţu, Carmen; Predoi, Daniela; Tatu, Mihaela

    2002-01-01

    The paper reports three clinical cases which have in common two elements: ocular toxoplasmosis and consecutive complicative cataract, the method of treatment, the evolution and the recovery visual acuity.

  10. Ressecção de bolsa hiperfuncionante para tratamento de hipotonia ocular crônica: relato de casos Resection of overfiltration bleb for the treatment of chronic ocular hypotony: case reports

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    Sebastião Cronemberger

    2004-08-01

    Full Text Available Relatar os resultados obtidos com a ressecção de bolsa hiperfuncionante pós-trabeculectomia (TREC com mitomicina C (MMC para o tratamento da hipotonia ocular crônica. Cinco pacientes portadores de hipotonia ocular crônica causada por hiperfunção de bolsa fistulante pós- trabeculectomia com mitomicina foram tratados pela ressecção da bolsa. O diagnóstico de hiperfunção da bolsa foi feito com base em critérios estabelecidos pelos autores. A hipotonia ocular foi revertida nos cinco pacientes, sem medicação num seguimento mínimo de cinco e máximo de 26 meses (média de 14,0 ± 7,9 meses. A ressecção da bolsa foi procedimento eficaz para reverter a hipotonia ocular crônica causada pela hiperfunção da mesma pós-trabeculectomia com mitomicina.To present the results of bleb resection for the treatment of overfiltering bleb after trabeculectomy with mitomycin C (MMC associated with chronic ocular hypotony. Five patients with chronic ocular hypotony caused by overfiltering bleb underwent bleb resection. The authors established the criteria for the diagnosis of overfiltering bleb. Ocular hypotony was reversed in all patients without medication. The mean follow-up was 14.0 ± 7.9 months. Bleb resection is a good approach for the treatment of chronic ocular hypotony secondary to overfiltering bleb.

  11. Líquido amniótico tópico: uma potencial nova alternativa para doenças da superfície ocular Topical amniotic fluid: a potential new alternative for ocular surface diseases

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    Guilherme Goulart Quinto

    2008-12-01

    Full Text Available O líquido amniótico banha o feto durante a vida intra-uterina e está em contato permanente com a superfície ocular durante este importante período do desenvolvimento. Ele contém uma série de fatores de crescimento que podem ter diversos efeitos sobre o processo cicatricial. Estes fatores aceleram a recuperação da sensibilidade corneana e regeneração nervosa após procedimentos cerato-refrativos, além de controlar a formação de cicatriz e o equilíbrio da superfície ocular após sua aplicação tópica. Centenas de diferentes proteínas têm sido identificadas no líquido amniótico humano e o papel de cada uma continua desconhecido. Os resultados obtidos até o momento sobre a aplicação de líquido amniótico em doenças de superfície ocular sugerem uma terapia promissora. Pesquisas estão sendo realizadas para identificar os efeitos dos fatores específicos do líquido amniótico sobre a inflamação ocular. O objetivo desta revisão é relatar as propriedades e utilizações atuais do líquido amniótico, bem como apresentar os recentes estudos relacionados ao uso deste líquido e doenças da superfície ocular.Amniotic fluid bathes the fetus during intrauterine life and is in permanent contact with the fetal ocular surface in this important period of development. It contains a series of growth factors that may have multiple effects on the wound healing process. These factors are thought to accelerate the recovery of corneal sensitivity and nerve regeneration after keratorefractive procedures, and also may control scar formation and balance the ocular surface after topical application. Hundreds of different proteins have been identified in the human amniotic fluid, and the role of each still not quite understood. The outcomes obtained so far with amniotic fluid application to ocular surface diseases suggest a promising therapy. Research is underway to identify the effects of specific factors of the amniotic fluid in ocular

  12. Cisticercosis ocular Ocular cysticercosis: presentation of one case

    Directory of Open Access Journals (Sweden)

    David Botero

    1992-01-01

    Full Text Available

    Se presenta el caso de un paciente con un cisticerco retiniano, tratado sin éxito con praziquantel, quien a los cinco meses del tratamiento presentó fibrosis y desprendimiento de la retina. Se realizó intervención quirúrgica y se encontró el cisticerco vivo. Desde antes de la operación el paciente había perdido la visión por el ojo afectado. Se hace una revisión sobre oftalmocisticercosis y se recomienda tratamiento quirúrgico oportuno y no usar los antihelmínticos con efecto sobre los cisticercos, como son praziquantel y albendazol.

    One case of ocular cysticercosis with retinal involvement, in which praziquantel treatment was ineffective, is presented. Five months after the medical treatment the patient presented with retinal detachment and fibrosis, loss of vision through the affected eye and at that time the parasite was observed alive. Surgical intervention was performed and the recovered cysticercus showed viability. A review on ophtalmocysticercosis is presented and recommendations are made to treat these cases by early surgery without prior administration of anticysticercus drugs such as praziquantel or albendazole.

  13. Ocular features of multiple system atrophy.

    Science.gov (United States)

    Garcia, Maria D; Pulido, Jose S; Coon, Elizabeth A; Chen, John J

    2018-01-01

    The aim of this paper is to gain better understanding of the ocular manifestations of multiple system atrophy (MSA), a neurodegenerative disorder rarely studied in terms of its ophthalmologic features. We performed a retrospective case series (1/1/05-12/31/14) to search for patients seen at Mayo Clinic, Rochester, MN, who had mention of MSA in the medical record and an eye examination, which yielded 285 cases. Of the 285, we identified 39 cases of true MSA. Each of these 39 patients was further reviewed for ocular abnormalities potentially related to MSA. Ocular findings potentially attributable to MSA were found in 64% of patients. Most common were dry eye (N = 14), conjugate eye movement abnormalities (N = 13), and ocular misalignment (N = 7). One patient had dry eye and monocular diplopia from trichiasis due to cicatricial pemphigoid, one had bilateral optic atrophy, and one had Adie's tonic pupil. Conjugate eye movement abnormalities (33%) and ocular misalignment (18%) were more common in patients with MSA-C. Patients with ocular findings, excluding dry eye, had a significantly shorter lifespan from time of initial neurologic symptoms to death. Our study confirms conjugate eye movement abnormalities and misalignment are common ocular findings in patients with MSA. Bilateral optic atrophy and cicatricial pemphigoid are possibly attributable to the disease. Ocular manifestations in MSA predict a poor prognosis as these patients have a significantly shorter lifespan. Therefore, we recommend patients with MSA have a comprehensive neuro-ophthalmologic exam at time of diagnosis, and thereafter, to screen for eye findings that may indicate a shorter lifespan. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Prosthetic management of an ocular defect

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    Siddesh Kumar Chintal

    2010-01-01

    Full Text Available The disfigurement associated with the loss of an eye can cause significant physical and emotional problems. Various treatment modalities are available, one of which is implants. Although implant has a superior outcome, it may not be advisable in all patients due to economic factors. The present article describes the prosthetic management of an ocular defect with a custom-made ocular prosthesis.

  15. The role of complement in ocular pathology

    OpenAIRE

    Bora, Nalini S.; Jha, Purushottam; Bora, Puran S.

    2008-01-01

    Functionally active complement system and complement regulatory proteins are present in the normal human and rodent eye. Complement activation and its regulation by ocular complement regulatory proteins contribute to the pathology of various ocular diseases including keratitis, uveitis and age-related macular degeneration. Furthermore, a strong relationship between age-related macular degeneration and polymorphism in the genes of certain complement components/complement regulatory proteins is...

  16. Caracterização clínica e histopatológica de bulbos oculares de cães e gatos (2005-2015

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    Paula D. Galera

    Full Text Available RESUMO: Objetivou-se realizar a caracterização clínica e histopatológica de bulbos oculares de cães e gatos, removidos cirurgicamente por indicação clínica, no período entre 2005-2015. Foram realizados 101 procedimentos de remoção do bulbo ocular, 93 enucleações (92% e 8 exenterações (8%. Os procedimentos foram realizados em 80 cães, (79% dos casos e em 21 gatos (21% dos casos. Os cães submetidos à intervenção cirúrgica apresentavam perfurações oculares (n=31, 39%, glaucoma (n=19, 24%, protrusão ocular (n=13, 16%, diagnósticos sugestivos de neoplasia (n=10, 12,5% e outros (n=3, 2,97%. Dentre os gatos os diagnósticos clínicos compreenderam perfuração ocular (n=9, 49%, glaucoma (n=3, 14,2%, microftalmia (n=3, 14,2%, sugestivo de neoplasia (n=2, 9,5%, protrusão ocular (n=2, 9,5% e outros (n=2, 9,5%. Vinte e sete amostras de bulbos oculares foram submetidas para avaliação histopatológica, sendo 23 provenientes de cães e quatro de gatos. Dentre as amostras de origem canina, sete exibiram achados histopatológicos compatíveis com glaucoma, sete perfurações oculares, seis neoplasias intraoculares, duas panoftalmites e um quadro de Phthisis bulbi. Nos bulbos oculares de gatos foram diagnosticadas duas neoplasias intraoculares, uma microftalmia e uma perfuração ocular. Constatou-se que o glaucoma secundário, as neoplasias e as perfurações oculares estão entre as principais causas de enucleação em cães, e associadas a alterações primárias como a ceratoconjuntivite seca e as uveítes. Estas afecções, diferentemente das neoplasias, podem ter êxito terapêutico mediante diagnóstico e tratamento precoces, prevenindo a cegueira e a remoção do bulbo ocular.

  17. Ocular toxoplasmosis: the influence of patient age

    Directory of Open Access Journals (Sweden)

    Gary N Holland

    2009-03-01

    Full Text Available The influence of patient age on various features of ocular toxoplasmosis has been a subject of study for many years. The age at which Toxoplasma gondii infection occurs in different populations is related to socioeconomic factors and studies suggest that ocular toxoplasmosis is a more severe disease at the extremes of age. The prevalence of ocular involvement is markedly different between individuals with congenital and those with post-natally acquired infections. Even among those with post-natally acquired infections, age influences the risk and timing of ocular involvement. The severity of toxoplasmic retinochoroiditis (in terms of lesion size, location and associated inflammation is also affected by patient age at the time of initial infection or recurrence. The risk of recurrent toxoplasmic retinochoroiditis is influenced by age at the time of initial infection and age at most recent episode of active disease. Understanding of relationships between ocular toxoplasmosis and patient age is incomplete; evidence has often been indirect and in some cases conflicting. The influence of patient age on ocular toxoplasmosis should be studied in a systematic manner to provide a better understanding of disease mechanisms and to provide clinical information that can used to establish better strategies for disease treatment and prevention.

  18. Ocular and periocular hemangiosarcoma in six horses.

    Science.gov (United States)

    Scherrer, Nicole M; Lassaline, Mary; Engiles, Julie

    2017-11-07

    To determine the characteristics of and prognosis for ocular and periocular hemangiosarcoma in horses. Six horses treated for ocular or periocular hemangiosarcoma. A retrospective review of medical records from 2007 to 2015 was performed to identify horses with a histologic diagnosis of ocular or periocular hemangiosarcoma. Signalment (age, sex, breed), duration of clinical signs, prior treatment, tumor size and location, medical and surgical treatment including postoperative chemotherapy, follow-up time, and outcome were obtained from medical records. Histopathology was reviewed by a board-certified pathologist. In six horses diagnosed with ocular or periocular hemangiosarcoma, no breed, age, or sex was overrepresented. Sites included the temporal limbus (3), third eyelid (2), and uvea (1). With the exception of one horse with uveal hemangiosarcoma, 5/6 horses had lightly pigmented periocular haircoat. Histologic features of ocular hemangiosarcoma in 6/6 cases included high cellularity, nuclear pleomorphism, and inflammation with a mitotic index ranging from 0 to 8 mitoses per 10 consecutive 400× fields. Five of six tumors displayed solar elastosis, indicating ultraviolet light-induced damage to sub-epithelial collagen. Treatment included surgical excision in all cases and was not associated with recurrence in 4/6. Three cases that received ancillary treatment with topical mitomycin C had no postoperative recurrence. Two cases with postexcisional recurrence had histologic evidence of incomplete excision. Complete surgical excision may be associated with resolution of periocular and ocular hemangiosarcoma in horses. Etiopathogenesis may include exposure to ultraviolet light. © 2017 American College of Veterinary Ophthalmologists.

  19. Ocular biometric changes after trabeculectomy

    Directory of Open Access Journals (Sweden)

    Azam Alvani

    2016-01-01

    Full Text Available This review article aimed to evaluate ocular biometric changes after trabeculectomy. The PubMed database was searched using the keywords “axial length” (AL, “anterior chamber depth” (ACD, “corneal astigmatism,” “corneal topography” and “trabeculectomy.” The extracted studies were categorized based on the evaluated parameters and the biometry method (contact and non-contact. Comparable studies with respect to their sample size were combined for statistical analysis. Twenty-five studies including 690 individuals which met the inclusion criteria were selected. After trabeculectomy, a significant and persistent AL reduction, with a range of 0.1-0.19 and 0.1-0.9 mm measured with contact and non-contact methods, respectively, was observed. With respect to topographic changes, 0.38-1.4 diopters (D with-the-rule (WTR astigmatism was induced postoperatively. All studies revealed ACD reduction immediately after surgery, which gradually deepened and approximated its preoperative levels on day 14. ACD reduction was not significant after that period in the majority of cases. In conclusion, changes in ACD is of small amount and of short period, thus it can be ignored; however, reported changes in AL and keratometry are of sufficient magnitude and can affect the refractive prediction of combined cataract surgery and trabeculectomy.

  20. Ocular microtremor laser speckle metrology

    Science.gov (United States)

    Al-Kalbani, M.; Mihaylova, E.; Collins, N.; Toal, V.; Coakley, D.; Boyle, G.

    2009-02-01

    Ocular Microtremor (OMT) is a continual, high frequency physiological tremor of the eye present in all subjects even when the eye is apparently at rest. OMT causes a peak to peak displacement of around 150nm-2500nm with a broadband frequency spectrum between 30Hz to 120Hz; with a peak at about 83Hz. OMT carries useful clinical information on depth of consciousness and on some neurological disorders. Nearly all quantitative clinical investigations have been based on OMT measurements using an eye contacting piezoelectric probe which has low clinical acceptability. Laser speckle metrology is a candidate for a high resolution, non-contacting, compact, portable OMT measurement technique. However, tear flow and biospeckle might be expected to interfere with the displacement information carried by the speckle. The paper investigates the properties of the scattered speckle of laser light (λ = 632.8nm) from the eye sclera to assess the feasibility of using speckle techniques to measure OMT such as the speckle correlation. The investigation is carried using a high speed CMOS video camera adequate to capture the high frequency of the tremor. The investigation is supported by studies using an eye movement simulator (a bovine sclera driven by piezoelectric bimorphs). The speckle contrast and the frame to frame spatiotemporal variations are analyzed to determine if the OMT characteristics are detectable within speckle changes induced by the biospeckle or other movements.

  1. Ocular features of CHARGE syndrome.

    Science.gov (United States)

    McMain, Karen; Blake, Kim; Smith, Isabel; Johnson, Judy; Wood, Ellen; Tremblay, Francois; Robitaille, Johane

    2008-10-01

    To detail the presence and severity of ocular and cranial nerve abnormalities found in individuals with CHARGE syndrome in a distinct geographic area. Nine individuals with CHARGE syndrome from Maritime Canada identified from a Canadian database were prospectively examined. Structural and sensorial defects associated with functional visual deficits were defined with ophthalmic and neurological evaluation. Consistent with current diagnostic criteria and the literature, colobomas were the major ophthalmic manifestation. These were typically bilateral chorioretinal colobomas involving the optic nerve. All subjects had bilateral severe sensorineural deafness (cranial nerve VIII), and 8 of 9 (89%) had facial nerve (cranial nerve VII) involvement (7 of 9 had unilateral involvement; 1 of 9 had bilateral involvement). Unique to this group of participants were the findings of anisometropia in 8 of the 9 (89%) patients, severe myopic astigmatism in 13 of the 18 eyes (72%), and limited elevation in adduction in 3 of 9 (33%) participants. Associated findings were strabismus, cataracts, microcornea, keratopathy, staphyloma, reduced stereopsis, superior visual field defects, and reduced visual acuity. The presence of coloboma plus another CHARGE feature warrants further investigation, including genetic screening for the CHD7 gene. Early recognition and management of sensory problems (visual, auditory, and vestibular) are crucial to ensure best psychomotor and cognitive development.

  2. Diagnostic tools in ocular allergy.

    Science.gov (United States)

    Leonardi, A; Doan, S; Fauquert, J L; Bozkurt, B; Allegri, P; Marmouz, F; Rondon, C; Jedrzejczak, M; Hellings, P; Delgado, L; Calder, V

    2017-10-01

    Ocular allergy (OA) includes a group of common and less frequent hypersensitivity disorders frequently misdiagnosed and not properly managed. The diagnosis of OA is usually based on clinical history and signs and symptoms, with the support of in vivo and in vitro tests when identification of the specific allergen is required. To date, no specific test is available for the diagnosis of the whole spectrum of the different forms of OA. The lack of recommendations on diagnosis of OA is considered a medical need not only for allergists but also for ophthalmologists. This position paper aims to provide a comprehensive overview of the currently available tools for diagnosing OA to promote a common nomenclature and procedures to be used by different specialists. Questionnaires, sign and symptom grading scales, tests, and potential biomarkers for OA are reviewed. We also identified several unmet needs in the diagnostic tools to generate interest, increase understanding, and inspire further investigations. Tools, recommendations, and algorithms for the diagnosis of OA are proposed for use by both allergists and ophthalmologists. Several unmet needs in the diagnostic tools should be further improved by specific clinical research in OA. © 2017 EAACI and John Wiley and Sons A/S. Published by John Wiley and Sons Ltd.

  3. An update on ocular allergy.

    Science.gov (United States)

    Shaker, Marcus; Salcone, Erin

    2016-10-01

    The update reviews prevalence, classification, cause, and treatment options for allergic eye disease. The incidence of allergic eye disease is underreported but may affect almost all patients with allergic rhinitis. Increased rates of oculonasal symptoms have been reported in the United States resulting in significant economic expenditures. The spectrum of allergic conjunctivitis and its differential considerations include seasonal and perennial conjunctivitis, vernal and atopic keratoconjunctivitis, and giant papillary conjunctivitis. Patients with allergic conjunctivitis have classic immunoglobulin E-mediated pathophysiology and treatments directed at allergen avoidance, traditional pharmacotherapy with oral antihistamines, topical dual-acting antihistamine/mast cell stabilizer agents, and treatment of tear film dysfunction are first-line management strategies. Immunotherapy is an effective treatment option and refractory cases may require ophthalmology comanagement for consideration of topical ester-based corticosteroid therapy and consideration of topical immunomodulators. Ocular allergy involving specific modifiable and treatable environmental sensitizations is common and often underrecognized. It can impair quality of life to varying degrees. Some cases are quite refractory to management and may require multidisciplinary coordination of care between allergy and ophthalmology specialists. Understanding classification, triggers, and treatment options is important in designing the most appropriate patient-tailored management plans.

  4. Ocular dangers of fencing wire.

    Science.gov (United States)

    McAllum, P; Barnes, R; Dickson, J

    2001-07-27

    To invesitgate the incidence and severity of penetrating eye injuries caused by fencing wire in the Waikato region. We reviewed the case notes for all penetrating eye injuries treated at Waikato Hospital during the past six years. Parameters recorded were patient age and sex, mechanism of injury, initial visual acuity, characteristics of injury, surgery performed and final visual outcome. The incidence of penetrating eye injuries in the Waikato region was 3.8 per 100,000 per year, based on an estimated catchment population of 350,000. We found fencing wire to be the third most common cause of penetrating eye injury, accounting for 8.8% of injuries, behind motor vehicle accidents and hammering which accounted for 26.3% and 20.0% of injuries, respectively. The fencing wire injuries involved men exclusively, with an average age of 41.7 years. Fencing wire injuries had worse presenting visual acuity than other injuries, involved the posterior segment of the eye more frequently and were more likely to develop bacterial endophthalmitis. They also underwent more surgical procedures and were more commonly associated with a poor visual outcome. Fencing wire is an important cause of visual loss in the Waikato region. We hope to raise awareness of its potential ocular dangers and to promote the use of appropriate eye protection.

  5. Manifestações oculares do paciente infectado pelo HIV atendido no Departamento de Oftalmologia da Universidade Federal de São Paulo Ocular manifestations of the HIV infected Patients at the Ophthalmology Department of São Paulo Federal University

    Directory of Open Access Journals (Sweden)

    K. T. F. Matos

    1999-12-01

    Full Text Available OBJETIVO: Avaliar as manifestações oculares do paciente HIV positivo. MATERIAL E MÉTODOS: É um estudo retrospectivo em 1100 pacientes ambulatoriais HIV positivo em três anos com ficha padrão e exame oftalmológico completo, atendidos no Departamento de Oftalmologia da Escola Paulista de Medicina. RESULTADOS: Dos 1100 pacientes, 869 (79% eram do sexo masculino e 231 (21% do feminino. Os fatores de risco mais importantes foram: homossexualidade masculina em 303 (27,55%, heterossexualidade em 272 (24,73%, usuários de drogas endovenosas em 168 (15,27% e causa indeterminada ou não revelada em 246 (22,36%. As queixas oculares mais freqüentes foram: 432 (39,27% pacientes com baixa da acuidade visual; 138 (12,55% com embaçamento visual; 64 (5,82% com dor ocular, 186 (16,9% com queixas inespecíficas e 235 (21,36% pacientes não apresentavam qualquer queixa. As manifestações oculares mais freqüentes foram: retinite por CMV em 246 (22,36% dos pacientes; exsudatos algodonosos em 110 (10%, blefarite em 51(4,64% e toxoplasmose ocular em 48 (4,36%. CONCLUSÃO: Houve progressão da doença entre os heterossexuais e aumento da incidência no sexo feminino nesta população estudada. Os que apresentavam queixas oculares foram a maioria. A manifestação ocular mais freqüente foi a retinite por CMV em 246 (22,36%. Encontramos 10% de exsudatos algodonosos.PURPOSE: To evaluate ocular manifestations of HIV-infected patients MATERIAL AND METHODS: A restropective study of 1,100 HIV positive out patients in 3 years with a standard complete ophthalmological exam. RESULTS: Eigth hundred and sixty nine (79% of the 1,100 patients studied were male and 231 (21% female. The most important risk factors were: male homossexuality in 303 cases (27.55%, heterossexuality in 272 (24.73%, endovenous drugs use in 168 (15.27%, and unknown cause in 246 (26.36%. Related to ocular complains, we found 432 (39.27% patients with decreased visual acuity, 138 (12.55% with visual

  6. Estudio sobre traumatismos oculares Study on ocular traumas

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    Ileana Miguel Pérez

    2004-06-01

    Full Text Available Se realizó estudio retrospectivo longitudinal de pacientes con traumatismos oculares mecánicos hospitalizados en el Instituto Superior de Medicina Militar "Dr. Luis Díaz Soto", desde 1988 hasta el 2002, con una casuística de 508 ojos de 479 pacientes. El procesamiento estadístico fue realizado con el mismo programa automatizado con el que se conformó la base de datos (Acces y se utilizaron de acuerdo con las características de las variables ß analizadas métodos estadísticos paramétricos y no paramétricos con una confiabilidad de un 95 % (a =0,05. Se obtiene una relación de 4:1 de predominio del sexo masculino, con una edad promedio de 27,4 años con valor mínimo de 2 años y máximo de 78 años. Los mecanismos más frecuentes de producción del accidente resultaron ser: las armas de fuego (22,7 % y la acción de martillar (21,4 %, teniendo en cuenta que el 38,2 % de los pacientes fueron militares. Las lesiones asociadas a los traumatismos más frecuentes resultaron ser el hipema y el hemovítreo, y se demostró que a medida que eran mayores disminuía considerablemente la agudeza visual final. Los traumatismos cerrados (41,3 % fueron más frecuentes y tuvieron mejores resultados visuales finales (66,7 % con visión mayor de 0.1 que el resto de los grupos de traumatismos abiertos (herida simple, contusión-herida, herida con CEIO y contusión-herida con CEIO. Las contusiones-heridas con CEIO fueron provocados en su mayoría por las armas de fuego y tuvieron los peores resultados visuales (60,5 % con visión menor de 0.1. La afectación del segmento posterior resultó ser un elemento que influyó de forma importante en los resultados visuales. Las complicaciones más frecuentes para los traumatismos cerrados fueron la hipertensión secundaria la catarata y el desprendimiento de retina. Para las heridas simples la catarata y para el resto de los traumatismos el desprendimiento de retina y la ptisis bulbi. Aproximadamente el 15 % de

  7. Systematic analysis of ocular trauma by a new proposed ocular trauma classification.

    Science.gov (United States)

    Shukla, Bhartendu; Agrawal, Rupesh; Shukla, Dhananjay; Seen, Sophia

    2017-08-01

    The current classification of ocular trauma does not incorporate adnexal trauma, injuries that are attributable to a nonmechanical cause and destructive globe injuries. This study proposes a new classification system of ocular trauma which is broader-based to allow for the classification of a wider range of ocular injuries not covered by the current classification. A clinic-based cross-sectional study to validate the proposed classification. We analyzed 535 cases of ocular injury from January 1, 2012 to February 28, 2012 over a 4-year period in an eye hospital in central India using our proposed classification system and compared it with conventional classification. The new classification system allowed for classification of all 535 cases of ocular injury. The conventional classification was only able to classify 364 of the 535 trauma cases. Injuries involving the adnexa, nonmechanical injuries and destructive globe injuries could not be classified by the conventional classification, thus missing about 33% of cases. Our classification system shows an improvement over existing ocular trauma classification as it allows for the classification of all type of ocular injuries and will allow for better and specific prognostication. This system has the potential to aid communication between physicians and result in better patient care. It can also provide a more authentic, wide spectrum of ocular injuries in correlation with etiology. By including adnexal injuries and nonmechanical injuries, we have been able to classify all 535 cases of trauma. Otherwise, about 30% of cases would have been excluded from the study.

  8. Categorical evaluation of the ocular irritancy of cosmetic and consumer products by human ocular instillation procedures.

    Science.gov (United States)

    Gao, Yang; Kanengiser, Bruce E

    2004-01-01

    The assessment of ocular irritation potential is an important part of safety testing for cosmetic and consumer products. The purpose of this investigation was to examine ocular irritancy levels elicited in humans by various categories of a specific class of cosmetic and consumer products that have a potential to enter the eye inadvertently during use. Test materials assessed belonged to one of seven categories, which included liquid makeup, shampoo, baby wash, mascara, eye makeup remover, powder eye shadow, and facial cleanser. These test materials were evaluated by human ocular instillation, followed by examinations, for which subjective perceptions of irritation were recorded, and component areas of ocular tissues were individually examined for inflammation and for the area and density of fluorescein staining patterns at 30 seconds and at 5, 15, 60, and 120 minutes post-instillation. Subjective and objective ocular irritation scores of 410 eyes were analyzed by product classification. Average score levels were determined for subjective responses, inflammation, and fluorescein staining patterns. This investigation determined that irritation levels of the evaluated test materials varied markedly with respect to product category, type of ocular irritation, and ocular tissue, demonstrating that these factors are important considerations for the prediction of the ocular irritancy of a test material.

  9. Clinical analysis of firearm ocular injury

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    Ying ZHANG

    2011-10-01

    Full Text Available Objective To investigate and analyze the clinical characters and prognosis of firearm ocular injury.Methods The traumatic characters of military inpatients with firearm-produced ocular injury(hospitalized in 15 military general hospitals during 2001-2005 were retrospectively reviewed and statistically analyzed.Results Of 716 military inpatients with ocular injuries(772 eyes,42(5.9%,all were men,aged 23.2±5.4 years were produced by firearm [with 60 injured eyes(7.8%].Among the 42 inpatients,18 cases(42.9% were binocular injury,and in 13 cases(31.0% it was complicated with brain and/or limb injury.The causes of injury included explosion(78.3% and foreign bodies in ocular region(68.3%,among which 41.7% of them with intraocular foreign bodies,and 72.0% were copper in nature.Combined ocular injuries were usually seen,but no endophthalmitis was found.Intraocular surgery was necessary for 61.7% of injured eyes,and vitrectomy was performed for 33.3% of injured eyes.According to the data collected at discharge from the hospital,15.0% of injured eyes were enucleated or eviscerated,8.3% showed monocular low vision and 11.9% binocular low vision,and 33.3% of them were monocular blind and 2.4% binocular blind.There was significant correlation between the post-traumatic visual acuity and the final vision(r=0.457,and the vision was improved significantly by treatment(P < .01.Conclusions The degree of trauma of firearm-induced ocular injury was usually severe and complicated with poor visual prognosis.Therefore the emphasis should be put on improvement of emergency and clinical treatment for firearm ocular injury.

  10. Condição ocular entre trabalhadores de uma indústria metalúrgica brasileira Ocular condition in a brazilian ironmaster industry

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    Thais Zamudio Igami

    2008-10-01

    Full Text Available OBJETIVO: Avaliar a condição ocular em população de trabalhadores de uma indústria metalúrgica paulista. MÉTODOS: Amostra de 2516 funcionários de uma fábrica na cidade de São Paulo foi submetida a uma avaliação oftalmológica como exame ocupacional periódico. Foi aplicado um questionário e realizado o exame de acuidade visual (Snellen e teste de Ishihara. Os funcionários com acuidade visual menor que 0,7 ou com diferenças maior que duas linhas ou que apresentassem alguma queixa ocular, passaram por avaliação complementar (biomicroscopia, refração, tonometria e fundo de olho. Prescreveu-se óculos conforme indicação. RESULTADOS: Houve predomínio do sexo masculino (62,5% e faixa etária de 20 a 29 anos (41%. A maioria não apresentava antecedentes oculares (97,6% ou sistêmicos (96,6%.A acuidade visual estava acima de 0,7 em 95,5% dos olhos e 84% não utilizavam correção. O diagnóstico final foi exame normal em 55% dos casos, presbiopia em 13.6%, astigmatismo miópico em 10% e hipermetrópico em 7,7% dos indivíduos. Baixa visão foi encontrada em 2,4%, cegueira unilateral em 0,4%, não havendo casos de cegueira ou de deficiência visual entre os trabalhadores. As principais causas de baixa visão foram erros refrativos e ambliopia. CONCLUSÃO: A maioria dos funcionários da indústria pesquisada apresentava exame oftalmológico normal e nenhum deles apresentava cegueira bilateral.PURPOSE: To evaluate the ocular condition in a brazilian ironmaster industry. METHOD: A prospective study was conducted in 2516 employees from an ironmaster brazilian industry in São Paulo city, Brazil. A questionnaire was applied and visual acuity and Ishihara test were performed in every individual. A complete ophthalmic evaluation (slit lamp examination, fundoscopy, tonometry and refractometry was done when the visual acuity was worse than 0.7 or when the worker had a greater diference between the eyes (more than two lines or when there were

  11. Study of ocular aberrations with age Estudo das aberrações oculares e idade

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    Helaine Vinche Zampar Athaide

    2009-10-01

    Full Text Available INTRODUCTION: Aging has various effects on visual system. Vision deteriorate, contrast sensitivity decreases and ocular aberrations apparently make the optical quality worse across the years. PURPOSE: To prospective evaluate ocular aberrations along the ages. METHODS: Three hundred and fifteen patients were examined, 155 were male (39.36% and 160 were female (60.63%. Ages ranged from 5 to 64 year-old, the study was performed from February to November, 2004. Patients were divided into 4 age-groups according to IBGE (Instituto Brasileiro de Geografia e Estatística classification: 68 patients from 5 to 14 year-old, 55 patients from 15 to 24 year-old, 116 from 25 to 44 year-old and 76 from 45 to 67 year-old. All patients had the following characteristics: best corrected visual acuity > 20/25, emmetropia or spherical equivalent INTRODUÇÃO: A idade afeta o sistema visual. A qualidade da visão se deteriora progressivamente com a idade, a sensibilidade ao contraste diminui e as aberrações oculares aumentam contribuindo para a piora da qualidade visual. OBJETIVO: Estudar prospectivamente as aberrações oculares entre as idades de 5 a 64 anos. MÉTODOS: Foram examinados 315 pacientes, 155 homens (39,36% e 160 mulheres (60,63% com idades entre 5 a 64 anos. O estudo foi realizado entre fevereiro a novembro de 2004. Os pacientes foram divididos em quatro grupos etários de acordo com a classificação do IBGE (Instituto Brasileiro de Geografia e Estatística: 68 pacientes entre 5 a 14 anos, 55 pacientes entre 15 a 24 anos, 116 pacientes entre 25 a 44 anos e 76 pacientes entre 45 a 67 anos de idade. Todos apresentavam acuidade visual corrigida para longe >20/25, emetropia ou equivalente esférico <3,5 DE, astigmatismo <1,75 DC ao exame sob cicloplegia, exame oftalmológico normal e sem cirurgia oftalmológica prévia. O Comitê de Ética da Universidade Federal de São Paulo aprovou esse protocolo. As aberrações foram medidas usando o sensor H

  12. Conjuntivite em animais de companhia

    OpenAIRE

    Gonçalves, Mariana Inês Pereira Coelho

    2015-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária, Ciências Veterinárias A conjuntivite é a doença ocular mais frequentemente diagnosticada em Medicina Veterinária, tanto em cães como em gatos. O facto de a conjuntiva ser uma membrana mucosa tão exposta a agentes externos faz com que esteja bastante suscetível a sofrer lesões, com consequente inflamação. Nesta dissertação abordam-se os diferentes tipos de conjuntivite, que são classificados de acordo com a sua etiologia. No Hospita...

  13. Ocular Biometry in Angle Closure

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    Mohammad Reza Razeghinejad

    2013-01-01

    Full Text Available Purpose: To compare ocular biometric parameters in primary angle closure suspects (PACS, primary angle closure glaucoma (PACG and acute primary angle closure (APAC. Methods: This cross-sectional study was performed on 113 patients including 33 cases of PACS, 45 patients with PACG and 35 subjects with APAC. Central corneal thickness (CCT, axial length (AL, anterior chamber depth (ACD and lens thickness (LT were measured with an ultrasonic biometer. Lens-axial length factor (LAF, relative lens position, corrected ACD (CACD and corrected lens position were calculated. The parameters were measured bilaterally but only data from the right eyes were compared. In the APAC group, biometric parameters were also compared between affected and unaffected fellow eyes. Logistic regression analysis was performed to identify risk factors. Results: No statistically significant difference was observed in biometric parameters between PACS and PACG eyes, or between affected and fellow eyes in the APAC group (P>0.05 for all comparisons. However, eyes with APAC had thicker cornea (P=0.001, thicker lens (P<0.0001, shallower ACD (P=0.009, shallower CACD (P=0.003 and larger LAF (P<0.0001. Based on ROC curve analysis, lower ACD, and larger LT, LAF and CCT values were associated with APAC. In the APAC group, LAF (P<0.0001 and CCT (P=0.001 were significant risk factors. Conclusion: This study revealed no significant difference in biometric characteristics in eyes with PACS and PACG. However, larger LAF and CCT were predictive of APAC.

  14. Ocular changes in primary hypothyroidism

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    Pekel Hamiyet

    2009-12-01

    Full Text Available Abstract Background To determine the ocular changes related to hypothyrodism in newly diagnosed patients without orbitopathy. Findings Thirty-three patients diagnosed to have primary overt hypothyroidism were enrolled in the study. All subjects were assigned to underwent central corneal thickness (CCT, anterior chamber volume, depth and angle measurements with the Scheimpflug camera (Pentacam, Oculus and cup to disc ratio (C/D, mean retinal thickness and mean retinal nerve fiber layer (RNFL thickness measurements with optical coherence tomography (OCT in addition to ophthalmological examination preceeding the replacement therapy and at the 1st, 3rd and 6th months of treatment. The mean age of the patients included in the study were 40.58 ± 1.32 years. The thyroid hormone levels return to normal levels in all patients during the follow-up period, however the mean intraocular pressure (IOP revealed no significant change. The mean CCT was 538.05 ± 3.85 μ initially and demonstrated no statistically significant change as the anterior chamber volume, depth and angle measurements did. The mean C/D ratio was 0.29 ± 0.03 and the mean retinal thickness was 255.83 ± 19.49 μ initially and the treatment did not give rise to any significant change. The mean RNFL thickness was also stable during the control visits, so no statistically significant change was encountered. Conclusions Neither hypothyroidism, nor its replacement therapy gave rise to any change of IOP, CCT, anterior chamber parameters, RNFL, retinal thickness and C/D ratio.

  15. Irritación ocular: Modelos alternativos

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    Raiza Vega Montalvo

    2001-12-01

    Full Text Available El ojo puede ser dañado accidentalmente por el uso de muchos productos de uso rutinario. Para facilitar la seguridad de los consumidores es necesario estimar el potencial de irritación ocular de estas sustancias químicas. Esta estimación está basada en los resultados obtenidos en el ensayo de Draize llevado a cabo en conejos. Sin embargo, avances en el desarrollo de la toxicología in vitro han permitido el uso de algunas alternativas para la evaluación del riesgo ocular; por lo que se presenta una revisión acerca de los diferentes métodos alternativos disponibles hasta el momento que permiten evaluar de una forma u otra los efectos tóxicos a nivel ocular.The eye may be accidentally damaged by many products of daily use. To guarantee the consumers’ safety it is necessary to estimate the eye irritation potential of these chemical substances. This estimation is based on the results obtained in the Draize rabbit eye irritation test. However, the advances attained in the development of in vitro toxicology have allowed the use of some alternatives to evaluate the ocular risk. Therefore, a review is made on the different alternative methods available up to now that make possible the evaluation in one way or another of the toxic effects at the ocular level.

  16. Ocular biomechanics study: current state and perspectives

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    S. Yu. Petrov

    2015-03-01

    Full Text Available Despite the fact that the eye represents a challenge for biomechanical research due to its size, over the last two decades, much data on ocular biomechanics were accumulated. Scleral and lamina cribrosa biomechanics contribute to our understanding of myopia and open-angle glaucoma; iris and trabecular meshwork biomechanics to that of angle-closure glaucoma; vitreous biomechanics to that of retinal detachment and ocular drug delivery; corneal biomechanics to that of keratoconus; and lens capsule biomechanics to that of cataract. This paper offers a general overview of recent advances in corneal, scleral, crystalline lens, and lamina cribrosa biomechanics and summarizes the results of experimental and clinical studies. Ocular biomechanics abnormalities affect etiology of many eye diseases. Ocular biomechanics plays an important role in the development of novel diagnostic methods, therapeutic and surgical procedures. Corneal biomechanics impacts etiology and pathogenesis of keratoconus as well as tonometry accuracy and explains corneal refractive surgery effect. Scleral biomechanics is associated with IOP and progressive myopia. Accommodative apparatus (ciliary body and crystalline lens is an important anatomic physiological structure. Recent studies uncovered the causes of agerelated loss of accommodation as a result of lens involution. Optic nerve head abnormalities due to IOP fluctuations are the key factor of glaucomatous neuropathy. They are directly associated with ocular biomechanics as well.

  17. Ocular biomechanics study: current state and perspectives

    Directory of Open Access Journals (Sweden)

    S. Yu. Petrov

    2015-01-01

    Full Text Available Despite the fact that the eye represents a challenge for biomechanical research due to its size, over the last two decades, much data on ocular biomechanics were accumulated. Scleral and lamina cribrosa biomechanics contribute to our understanding of myopia and open-angle glaucoma; iris and trabecular meshwork biomechanics to that of angle-closure glaucoma; vitreous biomechanics to that of retinal detachment and ocular drug delivery; corneal biomechanics to that of keratoconus; and lens capsule biomechanics to that of cataract. This paper offers a general overview of recent advances in corneal, scleral, crystalline lens, and lamina cribrosa biomechanics and summarizes the results of experimental and clinical studies. Ocular biomechanics abnormalities affect etiology of many eye diseases. Ocular biomechanics plays an important role in the development of novel diagnostic methods, therapeutic and surgical procedures. Corneal biomechanics impacts etiology and pathogenesis of keratoconus as well as tonometry accuracy and explains corneal refractive surgery effect. Scleral biomechanics is associated with IOP and progressive myopia. Accommodative apparatus (ciliary body and crystalline lens is an important anatomic physiological structure. Recent studies uncovered the causes of agerelated loss of accommodation as a result of lens involution. Optic nerve head abnormalities due to IOP fluctuations are the key factor of glaucomatous neuropathy. They are directly associated with ocular biomechanics as well.

  18. Frequency of Ocular Manifestation in Hemodialysis Patients

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    Eslami F

    2017-06-01

    Full Text Available Introduction: Chronic renal disease compromises of several renal involvements and several causative risk factors such as debates mellitus, hypertension, and old age. Ocular involvement seems to be related to chronic renal failure and hemodialysis as indicated by different studies. The aim of this study was the evaluation of prevalence of ocular manifestation in hemodialysis patients of Hamadan Besat hospital. Methods: This research was a cross sectional descriptive study, in which ocular signs in 74 hemodialysis patients, who referred to Besat hospital of Hamadan, Iran, during year 2015, were evaluated. Collected information related to patients included age, gender, dialysis duration, and background risk factors of chronic renal failure. All patients had been exanimated by an ophthalmologist. Results: Fifty percent of patients in the study were male and 50% were female. Average age of patients was 58.8 years and median duration of dialysis was 40.16 months. Mean visual acuity was 4.58 (of 10. Most common ocular manifestations were: macula abnormality (59.5%, cataract (56.7%, eye pain (56.7%, eye redness (52.7%, dry eyes (50%, and eyelid edema (43.2%, respectively. Conclusions: Hypertension and diabetes mellitus are the most common causes of chronic renal failure. The most common ocular manifestations were macular abnormality followed by cataract. According to high prevalence of these complications in hemodialysis patients, regular monitoring of patients for early detection and thus effective treatment seems to be necessary to improve their quality of life

  19. Impacts of Nanomedicines in Ocular Pharmacotherapy

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    Jaleh Barar

    2011-06-01

    Full Text Available Introduction: The integrity of the cells/tissues in anterior and/or posterior segments of the eye plays a crucial role in biofunctions of the vision. To maintain ocular homeostasis, selective restrictiveness of the ophthalmic membranes and barriers control must act on shuttling of biomolecules. Thus, not all attempts to apply de novo nanotechnology approaches for ocular pharmacotherapy have met with the same successes as those cited here in this review, and sometimes these novel technologies tools provoke a great deal of challenges and hurdles mainly because of functional presence of these barriers. Methods: Recent published articles related to application of ocular nanomedicines were reviewed and highlighted in this review article. Results: It seems the emergence of nanomedicines have arisen great hopes for ophthalmic pharmacotherapy, in which nanostructured medicines are expected to be able to cross the restrictive barriers of the eye. Although such fast inauguration of ocular nanomedicines will literally convey new challenges in the regulatory and translational processes, it will also grant a prolific platform from which many exciting, and yet unimagined, applications of biomedical nanotechnology will emerge for pharmacotherapy of the eye. Conclusion: This review provide recent advancements on ocular nanomedicines.

  20. The relationship between demodex and ocular discomfort.

    Science.gov (United States)

    Lee, Seok Hyun; Chun, Yeoun Sook; Kim, Jae Hoon; Kim, Eung Suk; Kim, Jae Chan

    2010-06-01

    To determine the correlative relationship between the prevalence of Demodex in eyelashes and the severity of ocular discomfort, by investigating the demographic epidemiology associated with Demodex. One hundred seventy patients underwent epilation of four eyelashes of each eye, and the number of Demodex was counted. The patients answered questionnaires about ocular surface discomfort and underwent ophthalmic examinations, including slit lamp, tear film breakup time (BUT), Schirmer test, and microbial culturing. The correlative relationship between the number of Demodex and these variable data was analyzed. Demodex was found in 120 (70%) of the 170 tested patients. Of 1360 eyelashes, 740 (54%) had Demodex. There was no significant difference in the prevalence of Demodex between males and females (P = 0.35). The number of Demodex showed significant positive correlations with increased age, ocular discomfort, and 1/BUT (P Demodex was significantly higher in patients with conjunctival papillary hypertrophy than in those without (P = 0.003). The presence or distribution of bacteria on eyelashes was similar between eyelids with and without Demodex. However, methicillin-resistant Staphylococcus aureus (MRSA) was detected more often on eyelids with Demodex, but this difference was not statistically significant. There is a strong correlation between the number of Demodex and the severity of ocular discomfort, suggesting that Demodex plays a pathogenic role in the ocular discomfort linked with aging.

  1. Complications of ocular paintball injuries in children.

    Science.gov (United States)

    Hargrave, S; Weakley, D; Wilson, C

    2000-01-01

    To evaluate the ocular complications of paintball injuries in children. The clinical course of four children with traumatic ocular paintball injuries was evaluated. All patients underwent a complete ocular examination. Their age, injuries sustained, surgical procedure(s) performed, presence of protective eyewear at the time of injury, and final visual outcome was assessed. The presence of directly related anterior and posterior segment abnormalities were also evaluated. Four boys sustained traumatic paintball injuries. Average patient age was 11.25 years (range: 10-12 years). None of the children were wearing ocular or facial protection at the time of the initial injury. All patients had hyphema and traumatic cataract, and some form of retinal pathology (vitreous hemorrhage, epiretinal membrane, retinal hemorrhage, and choroidal rupture). One child had a partial-thickness corneal laceration that did not require surgical intervention. All other patients underwent ophthalmic surgery. Final visual acuity was 20/30 or better in two patients, and 20/100 or worse in the others. The cause of decreased visual acuity in these children was directly related to macular pathology. Ocular injuries resulting from paintball impact are often severe and usually occur when the participants are not wearing eye protection or this protection becomes dislodged. Treatment of these injuries is sometimes limited to an attempt to salvage what remains of useful vision. Unfortunately, most of these sports-related injuries could have been prevented if patients wore adequate eye protection when involved in this sport.

  2. Recent Advances in Ocular Drug Delivery Systems

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    Shinobu Fujii

    2011-01-01

    Full Text Available Transport of drugs applied by traditional dosage forms is restricted to the eye, and therapeutic drug concentrations in the target tissues are not maintained for a long duration since the eyes are protected by a unique anatomy and physiology. For the treatment of the anterior segment of the eye, various droppable products to prolong the retention time on the ocular surface have been introduced in the market. On the other hand, direct intravitreal implants, using biodegradable or non-biodegradable polymer technology, have been widely investigated for the treatment of chronic vitreoretinal diseases. There is urgent need to develop ocular drug delivery systems which provide controlled release for the treatment of chronic diseases, and increase patient’s and doctor’s convenience to reduce the dosing frequency and invasive treatment. In this article, progress of ocular drug delivery systems under clinical trials and in late experimental stage is reviewed.

  3. Ocular rhinosporidiosis presenting as recurrent chalazion.

    Science.gov (United States)

    Mukhopadhyay, Somnath; Shome, Subrata; Bar, Prasenjit Kumar; Chakrabarti, Amit; Mazumdar, Swati; De, Avisek; Sadhukhan, Kaushik; Bala, Bivas

    2015-10-01

    Rhinosporidiosis, a granulomatous disease caused by Rhinosporidium seeberi, is widely prevalent in Sri Lanka and southern parts of India. Besides the eye, the lacrimal passage and nasal cavity are affected. The most common ocular involvement is a subconjunctival bleeding mass. Our case, a 9-year-old girl from a rural background with a history of pond water bathing, presented with a marginal chalazion involving the left lower lid. She had a history of chalazion involving the same site three months earlier which was managed by incision and curettage. A decision of surgical exploration was made and the evacuated mass was examined histologically showing evidence of rhinosporidiosis. This type of clinical presentation for ocular rhinosporidiosis (as recurrent chalazion) has not been reported earlier in the literature. This case emphasises that the clinicians from this part of the world must consider ocular rhinosporidiosis as differential diagnosis in cases with recurrent chalazion especially in a rural background with a habit of pond water bathing.

  4. Ocular manifestations of tick-borne diseases.

    Science.gov (United States)

    Raja, Harish; Starr, Matthew R; Bakri, Sophie J

    Tick-borne illnesses are a significant disease burden worldwide. Diagnosis is challenging and requires a high level of clinical suspicion. Ocular manifestations reported in association with tick-borne disease are mostly as case reports and small case series because of the relative infrequency with which they occur; however, given the global nature of health care and increase in travel in the 21st century, it is important for ophthalmologists to be aware of ocular manifestations of these diseases because early diagnosis may reduce morbidity and mortality. Here, we review of the literature of tick-borne diseases with reported ophthalmic findings. All known human tick-borne diseases are discussed, including a brief description of the causative agent, region of endemicity, vector, systemic symptoms, and any reported eye findings. When possible, we also address the strength of the evidence for these ocular associations. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Lymphocyte transformation in presumed ocular histoplasmosis

    Energy Technology Data Exchange (ETDEWEB)

    Ganley, J.P.; Nemo, G.J.; Comstock, G.W.; Brody, J.A.

    1981-08-01

    Lymphocytes from individuals with inactive macular disciform lesions of presumed ocular histoplasmosis challenged with three histoplasmin antigens incorporated tritiated thymidine at a significantly higher rate than histoplasmin-stimulated lymphocytes of matched control and peripheral scar groups. This finding is consistent with the etiologic association of the disciform ocular syndrome and previous systemic infection with Histoplasma capsulatum. The disciform group had a higher mean response than the other two groups to pokeweed mitogen but not to phytohemagglutinin and had higher mean counts per minute to the specific antigens Toxoplasma gondii, Blastomyces dermatitidis, Cryptococcus neoformans, Mycobacterium tuberculosis, M battery, and M gaus, but not to Candida albicans. These data would suggest that individuals with the disciform lesion of presumed ocular histoplasmosis have a hyperreactive cellular immune response; this response may play an important role in the development of the disciform.

  6. Ocular Fundus Photography as an Educational Tool.

    Science.gov (United States)

    Mackay, Devin D; Garza, Philip S

    2015-10-01

    The proficiency of nonophthalmologists with direct ophthalmoscopy is poor, which has prompted a search for alternative technologies to examine the ocular fundus. Although ocular fundus photography has existed for decades, its use has been traditionally restricted to ophthalmology clinical care settings and textbooks. Recent research has shown a role for nonmydriatic fundus photography in nonophthalmic settings, encouraging more widespread adoption of fundus photography technology. Recent studies have also affirmed the role of fundus photography as an adjunct or alternative to direct ophthalmoscopy in undergraduate medical education. In this review, the authors examine the use of ocular fundus photography as an educational tool and suggest future applications for this important technology. Novel applications of fundus photography as an educational tool have the potential to resurrect the dying art of funduscopy. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  7. Comparação entre os métodos de injeção de toxina botulínica em músculo ocular externo com o uso do eletromiógrafo e com o uso da pinça de Mendonça Electromyograph assistance and Mendonça's forceps - a comparison between two methods of botulinum toxin A injection into the extraocular muscle

    Directory of Open Access Journals (Sweden)

    Tomás Fernando Scalamandré Mendonça

    2005-04-01

    Full Text Available OBJETIVO: Comparar dois métodos de aplicação de toxina botulínica A (TBA em músculo ocular externo: com auxílio de eletromiógrafo (EMG e com a pinça de Mendonça. MÉTODOS: Foram analisados no Departamento de Oftalmologia da UNIFESP 29 pacientes que apresentavam estrabismo e baixa acuidade visual em um olho. Foram divididos em dois grupos: grupo I - 17 pacientes que receberam a toxina botulínica A por meio de injeção com auxílio da pinça de Mendonça e grupo II - 12 pacientes que receberam a toxina botulínica A por injeção guiada pelo eletromiógrafo. Os pacientes dos dois grupos foram avaliados no 7º e no 14º dia após aplicação. Compararam-se os resultados dos dois grupos neste período de tempo. Os testes de correlação de Friedman e Mann-Whitney foram usados para análise estatística. RESULTADOS: Houve diferença estatística entre as médias de desvio pré-aplicação e em pelo menos um período (7º ou 14º dia após aplicação, tanto no grupo dos pacientes em que foi utilizada a pinça, quanto no grupo de pacientes em que foi utilizado o eletromiógrafo. Não houve diferença estatística dos desvios pré-aplicação e pós-aplicação entre os dois grupos. CONCLUSÃO: Os dois métodos de aplicação da toxina botulínica A são equivalentes e portanto, o uso da pinça de Mendonça pode ser método alternativo ao uso do eletromiógrafo, para guiar a injeção de toxina botulínica A.PURPOSE: To compare two methods of botulinum toxin A (BTA injection into the extraocular muscle (EOM: the electromyographically (EMG guided injection and the injection using Mendonça's forceps. METHODS: Twenty-nine (29 patients with strabismus and low visual acuity in one eye were examined at the Department of Ophthalmology of UNIFESP. They were divided into 2 groups - group I with 17 patients receiving the botulinum toxin A injection using Mendonça's forceps, and group II with 12 patients receiving the toxin with electromyographical

  8. Hutchinson's sign as a marker of ocular involvement in HIVpositive ...

    African Journals Online (AJOL)

    Journal Home > Vol 100, No 3 (2010) > ... We examined the sensitivity of Hutchinsonfs sign as an indicator of ocular involvement in a consecutive ... Neither age nor CD4 count had predictive value for ocular involvement. ... Article Metrics.

  9. Ocular trauma: A tertiary hospital experience from Oman

    Directory of Open Access Journals (Sweden)

    Haitham H Al-Mahrouqi

    2017-01-01

    CONCLUSION: Ocular trauma is a common presentation at Al-Nahdha Hospital. Although the majority of trauma cases were minor without any resultant visual disability, OGI could have been prevented with better ocular protection in the workplace.

  10. Eye cosmetic usage and associated ocular comfort.

    Science.gov (United States)

    Ng, Alison; Evans, Katharine; North, Rachel; Purslow, Christine

    2012-11-01

    Eye cosmetics usage is commonplace and whilst some products such as eyeliner are applied with close proximity to the ocular surface, there is little knowledge of the short- and long-term ocular effects of eye cosmetic formulations. This study aimed to investigate the use of eye cosmetics and identify any relationships between ocular comfort and cosmetic usage. Results were collated from an online survey comprising 23 questions that recorded demographics, Ocular Surface Disease Index (OSDI) score, extent and range of eye cosmetic use and perceived comfort differences with and without eye cosmetics. The 1360 female respondents (median age 25, interquartile range 20-34 years) completed the survey; 83% reported using eye cosmetics regularly (≥ 3 times per week) with mascara being most commonly used. Fifty three per cent used at least three different eye cosmetics products regularly. OSDI scores of cosmetics users were similar to non-users (p = 0.083), but perceived comfort was greater when cosmetics were not used (p cosmetics users (use of products cosmetics were used. Median OSDI scores suggested a trend towards reduced comfort amongst eyeliner users (p = 0.07) although frequency and type of cosmetic products used did not appear to influence OSDI scores. This study shows the use of multiple eye cosmetics is extensive and associated with the perception of ocular discomfort. With such widespread use of these products, more research is required to assess the effect on the ocular surface and tear film, which may be underestimated. Ophthalmic & Physiological Optics © 2012 The College of Optometrists.

  11. Ocular disorders among workers exposed to mercury.

    Science.gov (United States)

    Gabal, M S; Raslan, O A

    1995-01-01

    Mercury vapor exposed workers may show ocular changes, as well as other systems affection. A sample of 84 workers in preparing mercury fulminate were examined for conjunctival corneal and lenticular manifestation of long duration exposure, together with mercury urinary output. Lens changes were found in 50% of the involved workers while keratopathy as recorded in 34.5% of them. No statistically significant association was found between the occurrence of eye lesions and levels of urinary elimination of mercury. These results suggest local absorption of this element is most probably the underlying cause of ocular affection.

  12. Ocular dominance and visual function testing

    OpenAIRE

    D. Lopes-Ferreira; Neves, H; A. Queiros; Faria-Ribeiro, M.; Peixoto-de-Matos, S. C.; J. M. González-Méijome

    2013-01-01

    To show the distribution of ocular dominance as measured with sensory and eye sighting methods and its potential relationship with high and low contrast LogMAR visual acuity in presbyopic subjects. Method. Forty-four presbyopes (48.5 ± 3.5 years) participated in this study. Ocular dominance was determined by eye sighting (hole-in-card) and sensorial (+1.50 D lens induced blur) methods. According to the dominance detected with each method (RE: right eye or LE: left eye), patients were classifi...

  13. Physiopathology and recording techniques of ocular movements

    OpenAIRE

    L. Gila; Villanueva, A; Cabeza, R

    2009-01-01

    En el control de la motilidad ocular intervienen varios sistemas funcionales. Los reflejos vestíbulo-oculares y optocinéticos son respuestas automáticas para compensar los movimientos de la cabeza y del entorno visual y poder estabilizar la imagen retiniana sobre un determinado punto de fijación. Los movimientos sacádicos son rápidos desplazamientos de la fijación de un punto a otro del campo visual. Los movimientos de persecución lenta consisten en el seguimiento de estímulos móviles con la ...

  14. New Developments in Ocular Surface Squamous Neoplasia

    Directory of Open Access Journals (Sweden)

    Ayşe Yağcı

    2014-09-01

    Full Text Available Ocular surface squamous neoplasia originates from conjunctiva epithelium and covers a broad spectrum of disease ranging from dysplasia to squamous cell carcinoma. Clinical features may vary from case to case. Traditional treatment of excision with no-touch technique combined with adjuvant therapies because of high recurrence rate. Main adjuvant treatments are cryotherapy and chemotherapy. In this review, clinical forms, differential diagnosis, American Joint Committee on Cancer classification and recent approaches to the management of ocular surface squamous dysplasia were described. (Turk J Ophthalmol 2014; 44: Supplement 8-14

  15. Pinwheel Stabilization by Ocular Dominance Segregation

    Science.gov (United States)

    Reichl, Lars; Löwel, Siegrid; Wolf, Fred

    2009-05-01

    We present an analytical approach for studying the coupled development of ocular dominance and orientation preference columns. Using this approach we demonstrate that ocular dominance segregation can induce the stabilization and even the production of pinwheels by their crystallization in two types of periodic lattices. Pinwheel crystallization depends on the overall dominance of one eye over the other, a condition that is fulfilled during early cortical development. Increasing the strength of intermap coupling induces a transition from pinwheel-free stripe solutions to intermediate and high pinwheel density states.

  16. Genetics in ocular inflammation--basic principles.

    Science.gov (United States)

    Wallace, G R; Niemczyk, E

    2011-02-01

    The ability to identify individuals at risk of ocular disease, or to determine the potential severity of disease or response to therapy is the current focus of much research. These studies are being led by genetic analysis of individuals to determine associations with alterations in gens that may explain manifestations of particular diseases. In this review we consider the basic principles behind genetic studies in general and of ocular disease in particular. We address the methodologies being utilised, and the results derived so far. The potential and pitfalls of such studies are relevant to the concept of personalised medicine and better defined clinical trials.

  17. Post-trabeculectomy ocular biometric changes.

    Science.gov (United States)

    Pakravan, Mohammad; Alvani, Azam; Esfandiari, Hamed; Ghahari, Elham; Yaseri, Mehdi

    2017-03-01

    Trabeculectomy is the most common surgical procedure for the management of glaucoma, which may significantly influence ocular biometry. Axial length and anterior chamber depth tend to decrease, while crystalline lens and choroidal thickness increase post-operatively. An increase in with-the-rule astigmatism is also observed after the procedure. Such biometric changes affect intraocular lens power calculation even years after the procedure. Non-contact biometric methods and postponing cataract surgery after trabeculectomy could reduce calculation errors associated with surgically induced alterations in ocular biometrics. © 2016 Optometry Australia.

  18. Emerging ocular biomarkers of Alzheimer disease.

    Science.gov (United States)

    van Wijngaarden, Peter; Hadoux, Xavier; Alwan, Mostafa; Keel, Stuart; Dirani, Mohamed

    2017-01-01

    Interest in reliable biomarkers of Alzheimer disease, the leading cause of dementia, has been fuelled by challenges in diagnosing the disease and monitoring disease progression as well as the response to therapy. A range of ocular manifestations of Alzheimer disease, including retinal and lens amyloid-beta accumulation, retinal nerve fiber layer loss, and retinal vascular changes, have been proposed as potential biomarkers of the disease. Herein, we examine the evidence regarding the potential value of these ocular biomarkers of Alzheimer disease. © 2016 Royal Australian and New Zealand College of Ophthalmologists.

  19. Perfil epidemiológico do trauma ocular penetrante antes e após o novo código de trânsito

    OpenAIRE

    Silber Paulo Caldas; Souza Luciene Barbosa de; Tongu Maira Tiyomi Sacata

    2002-01-01

    Objetivo: Comparar o perfil epidemiológico dos pacientes com trauma ocular penetrante (TOP) antes e após a regulamentação do novo código de trânsito. Métodos: Estudo retrospectivo de 253 pacientes com TOP examinados na Seção de Trauma Ocular (UNIFESP) de janeiro de 1997 a abril de 1999. Os pacientes foram divididos em dois grupos: Grupo I, pacientes com trauma ocular antes da implantação do novo código; Grupo II, história de trauma após sua implantação. Os pacientes foram avaliados em relação...

  20. Importância da ultra-sonografia ocular na avaliação pré-operatória de pacientes com catarata total The importance of ocular ultrasonography in the preoperative evaluation of patients with mature cataract

    Directory of Open Access Journals (Sweden)

    Álvaro Pedroso de Carvalho Lupinacci

    2004-02-01

    Full Text Available Com os avanços da cirurgia para catarata, o prognóstico da recuperação da visão aumentou drasticamente, tornando-se necessário prever resultados indesejados para a acuidade visual no pós-operatório. OBJETIVOS: Verificar a importância da ultra-sonografia ocular na avaliação pré-operatória do segmento posterior em pacientes com catarata madura, e relacionar possíveis doenças que possam comprometer os resultados cirúrgicos, sua prevalência e seus principais fatores de risco. MÉTODOS: Foi realizado estudo retrospectivo do prontuário de 262 pacientes em que houve a necessidade de ultra-sonografia ocular devido à presença de catarata madura, impedindo assim a avaliação fundoscópica do segmento posterior. Também foi avaliada a relação entre a presença dessas alterações e o sexo, idade, raça, história de trauma ocular, doenças sistêmicas e oculares e presença de catarata no olho contralateral. RESULTADOS: Encontraram-se alterações ecográficas em 24,8% dos exames realizados entre 1996 e 2001, dos quais o descolamento de retina (9,9% e as condensações vítreas (9,9% foram as mais comuns. CONCLUSÕES: Dentre os fatores de risco levantados como predisponentes para achados de ultra-sonografia ocular, a uveíte foi o único elemento estatisticamente significante. Não foi possível, pelos dados obtidos, correlacionar positivamente o trauma ocu-lar às patologias de segmento posterior descritas.With the new techniques of cataract surgery visual success has increased and it became necessary to foresee undesirable postoperative results regarding visual acuity. PURPOSE: To verify the role of ocular ultrasonography in the preoperative evaluation of patients with mature cataract searching for pos terior segment pathologies that may affect surgical results, their prevalence and the main associated risk factors. METHODS: A retrospective study was performed analyzing records of 262 patients indicated for ocular ultrasonography

  1. Ocular manifestations and outcome of treatment of Stevens-Johnson ...

    African Journals Online (AJOL)

    Final visual acuity depended on presenting visual acuity, how early in the disease patients presented, degree of inflammation and the degree of ocular surface cicatrisation. Conclusion: Ocular involvement in SJS results in widely differing degrees of ocular disability. Management involves medications and surgery.

  2. 21 CFR 886.4360 - Ocular surgery irrigation device.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Ocular surgery irrigation device. 886.4360 Section... (CONTINUED) MEDICAL DEVICES OPHTHALMIC DEVICES Surgical Devices § 886.4360 Ocular surgery irrigation device. (a) Identification. An ocular surgery irrigation device is a device intended to be suspended over the...

  3. Biomicroscopia ultra-sônica na avaliação da posição das lentes intra-oculares em uma técnica de fixação escleral Ultrasound biomicroscopy in the assessment of the intraocular lenses positioning in a transscleral fixation technique

    Directory of Open Access Journals (Sweden)

    Raul de Camargo Vianna Filho

    2000-10-01

    Full Text Available Objetivo: Avaliar pela biomicrospia ultra-sônica (UBM o posicionamento, em relação ao sulco ciliar, das alças de lentes intra-oculares (LIO, em uma técnica de fixação escleral, avaliando-se também se dois pontos de fixação são suficientes para que não haja inclinação da parte óptica. Métodos: Dezesseis olhos afácicos foram submetidos a implante LIO por uma mesma técnica de fixação escleral, realizados por um mesmo cirurgião. Um mês após a cirurgia, o posicionamento das alças das LIO foram avaliados pelo UBM, assim como distâncias entre as LIO e córnea. Os resultados foram submetidos a testes estatísticos. Resultados: Das 32 alças fixadas à esclera, oito estavam localizadas no sulco ciliar e 24 fora deste. Não houve diferença estatística nas distâncias entre LIO e córnea para alças posicionadas no sulco ciliar quando comparadas àquelas localizadas fora do sulco. Isto sugere que, além da distância ao limbo que se transfixa a esclera, outros fatores devem estar associados ao posicionamento da alça no sulco ciliar. As medidas LIO -- córnea realizadas na periferia das LIO às 3, 6, 9, e 12 horas foram semelhantes, mostrando que dois pontos de fixação são suficientes para que a LIO não fique inclinada. Conclusões: Outros fatores (por exemplo o ângulo de abertura do corpo ciliar, além da distância ao limbo na qual se transfixa a esclera, são importantes para o posicionamento das alças no sulco ciliar. Dois pontos de fixação são suficientes para que a LIO não apresente inclinação dentro do olho.Purpose: To assess, through ultrasound biomicroscopy (UBM, the positioning of the intraocular lenses (IOL haptics as related to the ciliary sulcus by using a scleral fixation technique; and to evaluate, as well, if two fixation points are sufficient to avoid tilting of the lenses. Methods: Sixteen aphakic eyes underwent an IOL implan-tation by means of the same scleral fixation technique, performed by the

  4. Management outcome of ocular surface conjunctival neoplasia ...

    African Journals Online (AJOL)

    Background: Ocular surface squamous neoplasia (OSSN)are aspectrum of lesions that arise from the squamous epithelium of the conjunctiva and cornea. They form the most frequent indication for orbital exenteration in Korle-bu Teaching Hospital, Accra. Poor management of early lesions leads to high rates of tumour ...

  5. [Improving the quality of glass ocular prostheses].

    Science.gov (United States)

    Nadareĭshvili, T B; Pakhomova, T S; Labutina, L V; Kachko, A L

    1979-01-01

    A critical analysis has been attempted of the current state-of-the-art in studying seleno-cadmium ruby glasses applicable for glass ocular prosthesis production. Better quality of these prostheses can be achieved by both the refinement of the ruby glass composition and by its strengthening (hardening) through proper methods.

  6. Ocular malignant lymphoma. A clinical pathological study

    Directory of Open Access Journals (Sweden)

    Panda A

    1987-01-01

    Full Text Available Eleven histologically proved cases of ocular malignant lymphoma diagnosed and managed during the year 1974-81 are reported. The follow-up period ranges from 2-7 years. The difficulties in diagnosis, treatment and prognosis are discussed.

  7. Ocular aberrations and wavefront aberrometry: A review

    Directory of Open Access Journals (Sweden)

    Holly A. Unterhorst

    2015-03-01

    Full Text Available Wavefront aberrations can be described as deviations of the wavefront exiting the eye froma reference wavefront that is aberration free and diffraction limited. Ocular aberrations canbe sub-categorised as lower and higher order aberrations. Ocular aberrations have promptedinterest amongst the ocular healthcare community owing to their influences on the visualfunctioning of patients as well as differences observed in ocular aberrations through the useof refractive surgery both pre- and post-operatively. Uncompensated refractive error remainsone of the most common reasons for which patients consult optometrists. Compensationof refractive error, or lower order aberrations, has become a routine procedure during anoptometric examination. However, there are some patients who experience visual symptomseven after their refractive errors have been compensated via spectacles or contact lenses.Higher-order aberrations may be the source of these visual disturbances. Refractive surgeryhas been found to influence and even induce various changes in higher-order aberrationspost-operatively, which in turn has led to increased interest in wavefront aberrations and howthe measurement of these aberrations can improve diagnosis and treatment within optometryand ophthalmology.

  8. Surgical rehabilitation following severe ocular burns.

    Science.gov (United States)

    Tuft, S J; Shortt, A J

    2009-10-01

    Chemical and thermal burns can cause devastating injuries to the anterior segment. The consequences of alkali injuries are notoriously severe due to the rapid penetration of these agents into the ocular tissues. Denaturation of tissue, inflammation, and scarring leads to loss of function. An understanding of the pathogenesis of tissue damage has lead to a rational approach to treatment. Emergency irrigation of the eye is essential and there is a 'window of opportunity' during the first 7-10 days after injury when medical treatment can significantly limit the potentially blinding consequences. The acute injury is followed by early and late reparative phases during which the prognosis can be further improved by surgical intervention. Early surgical intervention is targeted at protecting the ocular surface and encouraging re-epithelisation. Later, surgical treatments are directed at ocular surface reconstruction and restoration of vision. However, before any attempt is made at surface reconstruction, the ocular surface environment must be optimised by division of symblepharon, and correction of lid deformity and trichiasis. If there is conjunctivalisation of the corneal surface, limbal stem cell transplantation can restore a corneal epithelial cell phenotype, and transplantation of in vitroamplified corneal epithelial stem cells has been developed as an alternative to keratolimbal transfer techniques. Keratoplasty and cataract surgery may then be necessary to clear the visual axis. Finally, keratoprosthesis is an option for the most severely damaged eyes.

  9. Treatment of acute ocular chemical burns.

    Science.gov (United States)

    Sharma, Namrata; Kaur, Manpreet; Agarwal, Tushar; Sangwan, Virender S; Vajpayee, Rasik B

    2017-09-19

    Ocular chemical burns are an ophthalmic emergency and are responsible for 11.5%-22.1% of ocular injuries. Immediate copious irrigation is universally recommended in acute ocular burns to remove the offending agent and minimize damage. Conventional medical therapy consists of the use of agents that promote epithelialization, minimize inflammation, and prevent cicatricial complications. Biological fluids such as autologous serum, umbilical cord blood serum, platelet-rich plasma, and amniotic membrane suspension are a rich source of growth factors and promote healing when used as adjuncts to conventional therapy. Surgical treatment of acute ocular burns includes the debridement of the necrotic tissue, application of tissue adhesives, tenoplasty, and tectonic keratoplasty. Amniotic membrane transplantation is a novel surgical treatment that is increasingly being used as an adjunct to conventional treatment to promote epithelial healing, minimize pain, and restore visual acuity. Various experimental treatments that aim to promote wound healing and minimize inflammation are being evaluated such as human mesenchymal and adipose stem cells, beta-1,3 glucan, angiotensin-converting enzyme inhibitors, cultivated fibroblasts, zinc desferrioxamine, antifibrinolytic agents, antioxidants, collagen cross-linking, and inhibitors of corneal neovascularization. Copyright © 2017 Elsevier Inc. All rights reserved.

  10. Myopic anisometropia: ocular characteristics and aetiological considerations.

    Science.gov (United States)

    Vincent, Stephen J; Collins, Michael J; Read, Scott A; Carney, Leo G

    2014-07-01

    Anisometropia represents a unique example of ocular development, where the two eyes of an individual, with an identical genetic background and seemingly subject to identical environmental influences, can grow asymmetrically to produce significantly different refractive errors. This review provides an overview of the research examining myopic anisometropia, the ocular characteristics underlying the condition and the potential aetiological factors involved. Various mechanical factors are discussed, including corneal structure, intraocular pressure and forces generated during near work that may contribute to development of anisomyopia. Potential visually guided mechanisms of unequal ocular growth are also explored, including the influence of astigmatism, accommodation, higher-order aberrations and the choroidal response to altered visual experience. The association between binocular vision, ocular dominance and asymmetric refraction is also considered, along with a review of the genetic contribution to the aetiology of myopic anisometropia. Despite a significant amount of research into the biomechanical, structural and optical characteristics of anisometropic eyes, there is still no unifying theory, which adequately explains how two eyes within the same visual system grow to different endpoints. © 2014 The Authors. Clinical and Experimental Optometry © 2014 Optometrists Association Australia.

  11. Ocular Lens Implantation In Benin City, Nigeria

    African Journals Online (AJOL)

    Intra ocular lens implantation is a relatively new surgical procedure in developing countries, although it has been the norm in developed countries for over three decades. It is carried out during cataract surgery for the purpose of aphakic correction. The aim of the study was to assess the level of awareness of the general ...

  12. Orbito-Ocular Teratoma: A Case Report

    African Journals Online (AJOL)

    and retroperitoneal regions of the body.1. Teratomas arising from the head and neck region are uncommon.4 We report a case of orbito-ocular teratoma in an infant. Case Report. A seventeen day-old baby ... intestinal glands and neural tissue with retinoblasts showing severe anaplasia. There was local infiltration and foci ...

  13. Ocular complications of malaria treatment | Nwosu | Nigerian ...

    African Journals Online (AJOL)

    Malaria is endemic in Nigeria. With the emergence of chloroquine resistance various modes of treatment including parenteral quinine are employed with consequent untoward effects. This article reports two cases of severe ocular toxicity, including mimicry of intracranial space‑occupying lesion, from treatment of malaria ...

  14. Fabrication and characterization of porous hydroxyapatite ocular ...

    Indian Academy of Sciences (India)

    Unknown

    areas of medicine (Aoki et al 1987; Grote 1987; Shin et al 1992) also. The use of hydroxyapatite as an ocular .... the experimental error, throughout the whole process of fabrication. The median particle size of HAp powder used ... per medication and resolution took place within the 12th post-operative day (figures 9 a–d).

  15. DNA nanoparticles as ocular drug delivery platform

    NARCIS (Netherlands)

    de Vries, Jan Willem

    2015-01-01

    The field of DNA nanotechnology has progressed rapidly in recent years and now offers facile fabrication of a large variety of nanostructures of different shapes and geometries. In this thesis, short nucleic acid sequences are functionalized with hydrophobic units to form the basis of an ocular drug

  16. Evolution of the vestibulo-ocular system

    Science.gov (United States)

    Fritzsch, B.

    1998-01-01

    The evolutionary and developmental changes in the eye muscle innervation, the inner ear, and the vestibulo-ocular reflex are examined. Three eye muscle patterns, based on the innervation by distinct ocular motoneurons populations, can be identified: a lamprey, an elasmobranch, and a bony fish/tetrapod pattern. Four distinct patterns of variation in the vestibular system are described: a hagfish pattern, a lamprey pattern, an elasmobranch pattern, and a bony fish/tetrapod pattern. Developmental data suggest an influence of the hindbrain on ear pattern formation, thus potentially allowing a concomitant change of eye muscle innervation and ear variation. The connections between the ear and the vestibular nuclei and between the vestibular nuclei and ocular motoneurons are reviewed, and the role of neurotrophins for pattern specification is discussed. Three patterns are recognized in central projections: a hagfish pattern, a lamprey pattern, and a pattern for jawed vertebrates. Second-order connections show both similarities and differences between distantly related species such as lampreys and mammals. For example, elasmobranchs lack an internuclear system, which is at best poorly developed in lampreys. It is suggested that the vestibulo-ocular system shows only a limited degree of variation because of the pronounced functional constraints imposed on it.

  17. The ocular complications of an envenomous snakebite

    African Journals Online (AJOL)

    2012-07-10

    Jul 10, 2012 ... A snakebite constitutes a common acute medical emergency and has several systemic and even ocular consequences. According to Patil et al,1 the importance of this public health problem has largely been ignored by medical science. There are approximately 3 000 snake species worldwide, of which ...

  18. Síndrome isquémico ocular Ocular ischemic syndrome

    Directory of Open Access Journals (Sweden)

    Ailén Garcés Fernández

    2010-01-01

    Full Text Available El síndrome isquémico ocular es caracterizado por síntomas y signos oculares secundarios a la estenosis severa y prolongada ipsilateral de la arteria carótida interna extracraneal o de la arteria carótida común, ocasionalmente, se ha asociado a la oclusión de la arteria oftálmica. En general, se considera un diagnóstico poco usual y constituye la tercera causa más común de glaucoma neovascular con pobre pronóstico visual. Hallazgos oculares incluyen disminución progresiva de la visión, inflamación del segmento anterior, neovascularización del iris y del ángulo iridocorneal, glaucoma neovascular y retinopatía por hipoperfusión periférica. Describimos un paciente con severa estenosis carotídea ipsilateral y disminución progresiva de la visión por la isquemia ocular. Se realiza una revisión sobre el manejo de esta condición tan controversial.Ocular ischemic syndrome is characterized by ocular symptoms and signs that are secondary to prolonged and severe ipsilateral stenosis of extracranial internal carotid artery or of the common carotid artery; occasionally, ipsilateral ophthalmic artery obstruction can also be responsible. It is generally considered as an unusual diagnosis, and the 3rd most common cause in neovascular glaucoma with poor visual prognosis. Ocular findings include gradual onset of decreased vision, inflammation of the anterior segment, iris and iridocorneal angle neovascularization, neovascular glaucoma and peripheral hypoperfusion retinopathy. Here is a patient with l severe ipsilateral carotid stenosis and progressive visual loss due to ocular ischemia. A literature review on the best management of this so controversial condition was made.

  19. Systematic analysis of ocular trauma by a new proposed ocular trauma classification

    Directory of Open Access Journals (Sweden)

    Bhartendu Shukla

    2017-01-01

    Full Text Available Purpose: The current classification of ocular trauma does not incorporate adnexal trauma, injuries that are attributable to a nonmechanical cause and destructive globe injuries. This study proposes a new classification system of ocular trauma which is broader-based to allow for the classification of a wider range of ocular injuries not covered by the current classification. Methods: A clinic-based cross-sectional study to validate the proposed classification. We analyzed 535 cases of ocular injury from January 1, 2012 to February 28, 2012 over a 4-year period in an eye hospital in central India using our proposed classification system and compared it with conventional classification. Results: The new classification system allowed for classification of all 535 cases of ocular injury. The conventional classification was only able to classify 364 of the 535 trauma cases. Injuries involving the adnexa, nonmechanical injuries and destructive globe injuries could not be classified by the conventional classification, thus missing about 33% of cases. Conclusions: Our classification system shows an improvement over existing ocular trauma classification as it allows for the classification of all type of ocular injuries and will allow for better and specific prognostication. This system has the potential to aid communication between physicians and result in better patient care. It can also provide a more authentic, wide spectrum of ocular injuries in correlation with etiology. By including adnexal injuries and nonmechanical injuries, we have been able to classify all 535 cases of trauma. Otherwise, about 30% of cases would have been excluded from the study.

  20. Oncologia Moderna: Necessidade da Quebra de Paradigmas, Pré-conceitos e da Estagnação / Modern Oncology: Needs of Breaking Paradigms, Prejudice and Stagnation

    Directory of Open Access Journals (Sweden)

    Harley Francisco de Oliveira

    2016-03-01

    Full Text Available O câncer engloba uma vasta gama de neoplasias sólidas e não sólidas que possuem a capacidade de invadir tecidos adjacentes e potencial de disseminação à distância. É uma doença devastadora: representa uma patologia carregada de estigma social, com uma carga negativa bastante elevada na grande maioria das vezes, afetando todos os aspectos da vida dos pacientes bem como daqueles com quem convivem (familiares, amigos, cuidadores, etc.. É uma doença secular: as primeiras descrições remetem à Grécia antiga, onde foi descrito como uma doença semelhante a um caranguejo, karkínos, provavelmente devido sua característica infiltrativa em casos mais avançados, porém sua origem dá-se juntamente à origem da própria espécie. É uma doença democrática: salvo alguns casos onde os fatores de risco são bem conhecidos e podem ser evitados, o câncer não privilegia uma ou outra esfera social, limite geográfico, religião ou outro fator ambiental/social. O câncer é hoje a segunda causa de morte no país e no mundo, somente superado pelas doenças cardiovasculares; mais significativo ainda do que sua posição como causa de morte é o crescimento dessa taxa ao longo das últimas décadas e indícios evidentes de que continuará a crescer. As causas dessa impressionante mudança do perfil nosológico do Brasil, acompanhando uma tendência mundial, são em parte conhecidas. Em primeiro lugar, a melhoria das condições de vida e de saneamento básico, a crescente urbanização, a aplicação de medidas preventivas eficientes no controle de doenças infectocontagiosas, entre outros, contribuíram para uma redução significativa das doenças infecciosas e parasitárias. Por outro lado, estas mesmas causas produziram um sensível aumento da expectativa de vida, de 34 anos em 1.900 para 64 anos em 1980. A redução da mortalidade, principalmente nas faixas etárias mais elevadas (acima de 60 anos e a diminuição da fecundidade resultaram

  1. Epidemiological aspects of ocular superglue injuries.

    Science.gov (United States)

    Tabatabaei, Seyed Ali; Modanloo, Shokoufeh; Ghiyasvand, Arezoo Mohammadkhani; Pouryani, Abolghasem; Soleimani, Mohammad; Tabatabaei, Seyed Mehdi; Pakrah, Ahmad Reza; Masarat, Hamideh

    2016-01-01

    To report the frequency, associated risk factors and characteristics of cases referred to Farabi Eye Hospital with ocular superglue injuries. In a descriptive cross-sectional study conducted between December 2012 and February 2013, patients with ocular superglue injuries were evaluated. Age, sex, educational level, location, time, mechanism, type, site and time of eye injury were gathered through interview using a customized questionnaire. All participants had given consent to undergo thorough eye examination. Over the course of three months, 105 patients with ocular superglue injuries enrolled in the study, including 56(53.3%) men and 49(46.7%) women with the mean age of 24.7±11.6 (range, 2 to 53)y. The right eye, left eye and both eyes were involved in 52%, 42% and 6% of the patients, respectively. Most of injuries had occurred at home (72.4%) and at night (55%). More than half of patients (52.4%) did not take any primary aids following the ocular injury. Patient carelessness (78.1%), childhood curiosity and lack of parental supervision (11.4%), storing superglue in inappropriate places and inadvertently using superglue as eye drops due to poor vision (2.9%), inadequate awareness of superglue applications [used to stick on artificial nails (3.8%), artificial eyelashes (1.9%) and broken tooth (1%)] and being assaulted with glue (1%) were common risk factors. The frequency of ocular superglue injuries in patients referred to Farabi Eye Hospital is relatively high. This finding underlines the importance of public education and awareness about superglue injuries to the eye and taking protective measures and safety strategies in order to prevent these injures.

  2. Ocular toxicity of authentic lunar dust

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    Meyers Valerie E

    2012-07-01

    Full Text Available Abstract Background Dust exposure is a well-known occupational hazard for terrestrial workers and astronauts alike and will continue to be a concern as humankind pursues exploration and habitation of objects beyond Earth. Humankind’s limited exploration experience with the Apollo Program indicates that exposure to dust will be unavoidable. Therefore, NASA must assess potential toxicity and recommend appropriate mitigation measures to ensure that explorers are adequately protected. Visual acuity is critical during exploration activities and operations aboard spacecraft. Therefore, the present research was performed to ascertain the ocular toxicity of authentic lunar dust. Methods Small (mean particle diameter = 2.9 ± 1.0 μm, reactive lunar dust particles were produced by grinding bulk dust under ultrapure nitrogen conditions. Chemical reactivity and cytotoxicity testing were performed using the commercially available EpiOcularTM assay. Subsequent in vivo Draize testing utilized a larger size fraction of unground lunar dust that is more relevant to ocular exposures (particles Results In vitro testing indicated minimal irritancy potential based on the time required to reduce cell viability by 50% (ET50. Follow-up testing using the Draize standard protocol confirmed that the lunar dust was minimally irritating. Minor irritation of the upper eyelids was noted at the 1-hour observation point, but these effects resolved within 24 hours. In addition, no corneal scratching was observed using fluorescein stain. Conclusions Low-titanium mare lunar dust is minimally irritating to the eyes and is considered a nuisance dust for ocular exposure. No special precautions are recommended to protect against ocular exposures, but fully shielded goggles may be used if dust becomes a nuisance.

  3. Roles of IL-8 in ocular inflammations: a review.

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    Ghasemi, Hassan; Ghazanfari, Tooba; Yaraee, Roya; Faghihzadeh, Soghrat; Hassan, Zuhair Mohammad

    2011-12-01

    This review presents the current in vitro and in vivo animal and human research on the roles of IL-8 in ocular inflammatory diseases. Data sources were a literature review using Pub Med, Medline, and ISI databases (from 1990 to 2011). Search items included interleukine-8 (IL-8), CXCL8, chemokines, cytokines, alone or in combination with the, serum, aqueous, vitreous, eye, ocular, ocular tissues, ophthalmic, and review. IL-8 may be involved in primary or secondary ocular inflammations. Ocular effects of IL-8 differ based on the source of the secretion and site of the action. The most important effects of IL-8 in the eyes are angiogenic activities and induction of ocular inflammation. IL-8 plays important roles in ocular inflammation and angiogenesis in conjunctiva, cornea, iris, retina, and orbit. Anti-IL-8 targeted immunotherapy has been introduced as an important treatment modality, provided that IL-8 signal blocking takes place in desired areas and tissues.

  4. Ocular hemodynamics and glaucoma: the role of mathematical modeling.

    Science.gov (United States)

    Harris, Alon; Guidoboni, Giovanna; Arciero, Julia C; Amireskandari, Annahita; Tobe, Leslie A; Siesky, Brent A

    2013-01-01

    To discuss the role of mathematical modeling in studying ocular hemodynamics, with a focus on glaucoma. We reviewed recent literature on glaucoma, ocular blood flow, autoregulation, the optic nerve head, and the use of mathematical modeling in ocular circulation. Many studies suggest that alterations in ocular hemodynamics play a significant role in the development, progression, and incidence of glaucoma. Although there is currently a limited number of studies involving mathematical modeling of ocular blood flow, regulation, and diseases (such as glaucoma), preliminary modeling work shows the potential of mathematical models to elucidate the mechanisms that contribute most significantly to glaucoma progression. Mathematical modeling is a useful tool when used synergistically with clinical and laboratory data in the study of ocular blood flow and glaucoma. The development of models to investigate the relationship between ocular hemodynamic alterations and glaucoma progression will provide a unique and useful method for studying the pathophysiology of glaucoma.

  5. Alergia ocular: un reto diagnóstico Ocular allergy: a diagnostic challenge

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    Ricardo Cardona Villa

    2007-12-01

    Full Text Available El ojo es uno de los órganos más sensibles y está permanentemente expuesto a diversos agentes ambientales. Dado que la conjuntiva es un tejido inmunológicamente activo, no es sorprendente que sea un sitio común de respuestas alérgicas. Las alergias oculares son un grupo de enfermedades que afectan la superficie conjuntival y están asociadas usualmente a reacciones de hipersensibilidad tipo 1. Pueden ser divididas en varias categorías: conjuntivitis alérgica estacional, conjuntivitis alérgica perenne, queratoconjuntivitis vernal y queratoconjuntivitis atópica. La inflamación de la superficie ocular produce prurito, lagrimeo, edema conjuntival y fotofobia. Como en otras enfermedades alérgicas, se puede desarrollar una condición crónica, acompañada de remodelación de los tejidos oculares. Las estrategias para el tratamiento de la alergia ocular han aumentado exponencialmente y los clínicos disponen de un inventario cada vez mayor de agentes dirigidos a la protección del ojo contra la inflamación. En este trabajo presentamos una revisión sobre las principales formas de alergia ocular, haciendo énfasis en el cuadro clínico, el diagnóstico y las nuevas opciones terapéuticas disponibles en la actualidad. The eye, one of the most sensitive organs, is permanently exposed to different environmental agents. Since the conjunctiva is an immunologically active tissue, it is not surprising for it to be a common site for allergic responses. Ocular allergies constitute a group of diseases affecting the conjunctival surface; they are usually associated with type 1 hypersensitivity reactions. This disorder can be divided into several categories: seasonal allergic conjunctivitis, perennial allergic conjunctivitis, vernal keratoconjunctivitis and atopic keratoconjunctivitis. Ocular surface inflammation results in itching, tearing, conjunctival edema, and photophobia. As is the case with other allergic diseases, a chronic situation can also

  6. Tempo de reação visual em jogadores de futebol

    OpenAIRE

    Jorge, Jorge; Fernandes, Paulo Rodrigues; Queirós, A

    2014-01-01

    Publicado em "Abstract book CIOCV 2014" Objetivo: Determinar a influência da lateralidade e dominância ocular no tempo de reação visual em jogadores de futebol. Métodos: Determinou-se la dominância ocular e a dominância motora (mão) em jogadores de futebol. Também se determinou o tempo de reação motor e sensorial (sportvision reaction time app). Realizaram-se as medidas do tempo de reação visual sensorial e motor 3 vezes para cada uma das mã...

  7. Prognostic value of an ocular trauma score in ocular firecracker trauma.

    Science.gov (United States)

    Qi, Ying; Zhu, Yu

    2013-01-01

    The aim of this study was to report the incidence and management of ocular firecracker trauma and to assess the predictive value of an Ocular Trauma Score (OTS) in ocular firecracker trauma. The study includes consecutive case study and retrospective analysis of ocular firecracker trauma. Numerical values rendered to the OTS variables (visual acuity, rupture, endophthalmitis, perforating or penetrating injury, retinal detachment, and afferent pupillary defect) at presentation were summated and converted to OTS categories. The likelihood of the final visual acuities in each category were calculated. The sensitivity and specificity of OTS were also determined. Forty-eight patients (54 eyes) were enrolled in the study. Male patients accounted for 85.4%. Of the total patients, 62.5% were younger than 15 years. Bystanders accounted for 47.9%. The average follow up was 18.5±3.6 months. The most common clinical manifestation was ocular penetrating or perforating injury. Of the total number of patients, 53.7% had best-corrected vision, at the time of their last follow up, ranging from 20/50-20/200. The OTS has 100% sensitivity and specificity to predict nonlight perception, light perception/hand motion, and 1/200-19/200. The OTS has 45% sensitivity and 100% specificity to predict vision of 20/200-20/50. The OTS has 100% sensitivity and 65% specificity to predict vision of ≥20/40. The clinical manifestations of ocular firecracker trauma in Zhengzhou are more severe than in other countries, but similar to reports of other cities of comparable size to that in China. The OTS has good predictive value for ocular firecracker trauma with 100% sensitivity and specificity to predict a final vision of nonlight perception, light perception/hand motion, and 1/200-19/200.

  8. OCULAR DISORDERS IN CHILDREN WITH DEVELOPMENTAL DELAY

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    Meera Suresh Joshi

    2017-08-01

    Full Text Available BACKGROUND In India, an estimated 1.5-2.5% children below 2 years of age are developmentally delayed. A higher incidence of ocular disability is seen in these children, refractive errors and strabismus being most common. These can add to the overall burden of health as most of them have developmental comorbidities. The aim of the study is to study the ocular disorders in children with developmental delay. MATERIALS AND METHODS We studied 112 children between the 2-12 years of age diagnosed to have developmental delay. All the subjects underwent a detailed ophthalmic evaluation including visual acuity testing using Snellen’s charts (3m and 6m and Log MAR charts (recorded as per Snellen’s vision testing to maintain uniformity, cycloplegic refraction, torchlight and slit-lamp evaluation and dilated fundus examination. The data was tabulated and represented using bar diagrams, Pie charts and graphs. The results were expressed as percentages. Design-Cross-sectional, observational study. RESULTS 66 boys and 46 girls (total 112 were evaluated. The mean age of the study population was 7.8 years ± 2.4 SD. The aetiology of developmental delay was cerebral palsy (64%, Down syndrome (22%, autism (7%, intellectual disability (4.5% and 1 case each of congenital hypothyroidism and ataxia telangiectasia. The prevalence of ocular disorders was found to be 84.8%, which was slightly higher in girls (87% as compared to boys (83%. Refractive error (79.5% was the commonest ocular disorder followed by strabismus (46.4%. Astigmatism (44.6% was the commonest refractive error, which was divided into myopic astigmatism (19.6%, hyperopic astigmatism (13.8% and mixed astigmatism (11.2%. Simple hyperopia was seen in 21.9% subjects and simple myopia in 12.1%. Exotropia (52% was commoner than esotropia (48%. Other ocular abnormalities included optic atrophy, nystagmus, epicanthal folds, cataract, mongoloid slant, ptosis, telecanthus, conjunctival telangiectasia and

  9. Reprodutibilidade na classificação do teste de cristalização do filme lacrimal em pacientes com síndrome de Sjögren Reproducibility of the classification of ocular ferning patterns in Sjogren's syndrome patients

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    Sergio Felberg

    2008-04-01

    Full Text Available OBJETIVO: Verificar a reprodutibilidade da classificação dos padrões do teste de cristalização do filme lacrimal utilizando cinco examinadores diferentes e comparar os padrões de cristalização de pacientes portadores da síndrome de Sjögren com os de indivíduos não portadores de doenças da superfície ocular. MÉTODOS: Análise da cristalização da lágrima de 29 pacientes com Sjögren e 45 pacientes sem doenças da superfície ocular, através de microscópio com luz polarizada, utilizando a classificação de Rolando. Para fins estatísticos foi estudada a curva ROC (Receiver Operating Characteristic para determinar a melhor nota de corte do exame que separa indivíduos normais dos portadores da síndrome, índice de concordância Kappa (pPURPOSE: To verify the reproducibility of Rolando's classification of the tear ferning test using five different examiners and to compare the patterns of crystallization found in Sjögren's syndrome patients and normal subjects. METHODS: Tear ferning analysis of 29 patients with Sjögren's syndrome and of 45 patients without ocular disease were done using polarized light microscopy and the Rolando classification for tear ferning. Five examiners classified the ferning patterns of all the patients. ROC curve (Receiver Operating Characteristic was used to find out the best score for the correct syndrome diagnosis. Kappa index (p<0.0001 was used to compare the results of the examiners among them and check the test's reproducibility. Charts were drawn to compare the two groups' results. RESULTS: Throught the ROC curve the score of 2.50 for diagnosis of Sjögren's syndrome was stabilished. Considering the aggregated patterns I with II and III with IV, the examinors' level of pattern agreement was excellent (Kappa ranging from 0.82 to 0.97, p<0.0001. The group with Sjögren's syndrome was classified mostly as patterns III and IV and the patients without ocular disease mostly as I and II. CONCLUSION: The

  10. Implante intra-ocular de lentes dobráveis "piggyback" em paciente portador de catarata congênita no primeiro ano de vida: relato de caso Piggyback foldable intraocular lens implant in patient with congenital cataract in the first year of life: case report

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    Leonardo Akaishi

    2004-12-01

    Full Text Available No presente relato os autores descrevem um caso de catarata congênita unilateral tratada cirurgicamente com implante intra-ocular de lentes dobráveis "piggyback", ainda não descrito na literatura nacional. São analisadas as diferenças e semelhanças com outros casos descritos na literatura.The authors report a case of congenital cataract, which was treated with piggyback foldable intraocular lens implant, not described in the Brazilian literature. The differences and similarities are analyzed with other reported cases in the literature.

  11. Amniotic membrane transplantation for acute ocular burns.

    Science.gov (United States)

    Clare, Gerry; Suleman, Hanif; Bunce, Catey; Dua, Harminder

    2012-09-12

    Ocular surface burns can be caused by chemicals (alkalis and acids) or by direct heat. Amniotic membrane transplantation (AMT) performed in the acute phase (day 0 to day 7) of an ocular surface burn is reported to relieve pain, accelerate healing and reduce scarring and blood vessel formation. The surgery involves applying a patch of amniotic membrane (AM) over the entire ocular surface up to the eyelid margins. To assess the effects of AMT on the eyes of people having suffered acute ocular surface burns. We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2012, Issue 6), MEDLINE (January 1946 to June 2012), EMBASE (January 1980 to June 2012), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to June 2012), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 11 June 2012. We included randomised trials of medical therapy and AMT applied in the first seven days after an ocular surface burn compared to medical therapy alone. Two authors independently assessed the risk of bias of included studies and extracted relevant data. We contacted trial investigators for missing information. We summarised data using risk ratios (RRs) and mean differences (MDs) as appropriate. We included one RCT of 100 participants with ocular burns that were randomised to treatment with AMT and medical therapy or medical therapy alone. A subset of patients (n = 68) who were treated within the first seven days of the injury met the inclusion criteria and were included in the analysis. The remaining 32 eyes were excluded. The included subset consisted of 36 moderate (Dua classification II-III) and 32 severe (Dua

  12. [Conjunctival microbiota in patients with ocular allergy].

    Science.gov (United States)

    Libório, Alexandre Mattoso; Nishiwaki-Dantas, Maria Cristina; Mimica, Lycia Mara Jenne; Dantas, Paulo Elias Correa; Lima, Ana Luísa Höfling de

    2005-01-01

    To evaluate de presence of conjunctival aerobic microbiota in patients with ocular allergy as compared to a control group. One hundred and thirty-three patients were evaluated from April to June 2001 and divided into 2 groups. Sixty-three patients with allergic conjunctivitis (without medication) were in group A and 70 patients from the general outpatient clinic were in group B (control group). Samples from the conjunctival sac of the right eye were collected and cultured in solid media (blood, chocolate and Sabouraud agar). In group A, 30 cultures (47.7%) were positive and 6 (8.6%) in group B. Seven bacteria were isolated from group A and 4 from group B. Statistical analysis revealed significant association between positive cultures and allergic conjunctivitis. Bacterial microbiota was more frequently found in patients with ocular allergy.

  13. OCULAR MANIFESTATIONS OF VIRAL INFECTIONS IN CHILDREN

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    E. Yu. Markovа

    2016-01-01

    Full Text Available In case of viral infections, ophthalmologists, pediatricians and general practitioners should all be aware of ocular manifestations of these diseases. According to our observations, despite the presence of corneal disorders, in 95 percent of children changes were reversible and in 1.5 months visual acuity was high. Only in five percent of cases despite the intensive therapy, patients had bacterial complications, causing a decrease in visual acuity.The combined  efforts of infectious disease specialists and ophthalmologists as well as timely and proper treatment are required to reduce the inflammation symptoms and prevent complications. By adding Ophtalmoferon® medication to the complex therapy of ocular surface diseases we observed its high therapeutic efficacy and a good safety profile. This medication is available in the form of ready-to-use eye drops, unlike other antiviral agents, improving  its compliance in outpatients.

  14. Reduction of intra-ocular pressure by ocular compression before combined peri- and retrobulbar block.

    Science.gov (United States)

    Kallio, H; Harju, M P; Ihanamäki, T; Vesti, E T; Kivelä, T

    2011-04-01

    The intra-ocular pressure immediately before glaucoma surgery can be raised. We wished to investigate if ocular compression for 20 min before a combined peri- and retrobulbar injection would result in a lower pressure after the block. Sixty consecutive patients scheduled for filtration surgery were randomly assigned to receive ocular compression using an external pressure device for 20 min before combined peri- and retrobulbar injection (intervention group, who also received compression after the block) or to a control group in whom pressure was applied only after the block was completed. The intra-ocular pressure was measured at baseline, after the 20-min pre-injection compression (intervention group), after injecting the block, and after the 10-min post-injection compression. The pressure did not differ between groups at baseline, after the block or after the post-injection compression. In the intervention group, the compression before the block reduced the median (IQR [range]) pressure from 21.0 (17.0-25.0 [12.0-40.0]) mmHg to 16.8 (12.5-22.5 [7.5-33.5]) mmHg (pintra-ocular pressure, but applying an additional compression for 20 min before injecting the block is not beneficial. © 2011 The Authors. Anaesthesia © 2011 The Association of Anaesthetists of Great Britain and Ireland.

  15. Superfície ocular e hepatite C

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    Rachel Lopes Rodrigues Gomes

    2011-04-01

    Full Text Available Objetivos: Avaliar os resultados dos testes utilizados para o diagnóstico de olho seco em portadores do vírus da hepatite C, e verificar se há relação entre a duração conhecida da doença e a intensidade das alterações da superfície ocular. MÉTODOS: Foram avaliados 25 pacientes portadores do vírus da hepatite C não tratados e 29 indivíduos com testes sorológicos negativos para hepatite C. Nos dois grupos, foi realizada a mesma sequência de exames: biomicroscopia, teste de cristalização da lágrima, tempo de ruptura do filme lacrimal, avaliação da córnea com fluoresceína, teste de Schirmer I, avaliação da córnea e conjuntiva com corante rosa bengala e estesiometria da córnea. Os pacientes também foram questionados com relação ao tempo conhecido de infecção pelo vírus da hepatite C. RESULTADOS: O grupo com hepatite C apresentou valor menor que o encontrado nos indivíduos sem hepatite C, no teste de Schirmer I tanto para o olho direito (p=0,0162 como esquerdo (p=0,0265. Para o tempo de ruptura do filme lacrimal verificou-se média inferior no grupo com hepatite C nos dois olhos; porém, a diferença apresen tou significância estatística apenas no olho esquerdo (p=0,0007, não sendo detectada diferença no olho direito (p=0,0793. Com relação ao dano presente na superfície ocular, verificado pela pontuação no teste de coloração com rosa bengala, observou-se média superior no grupo com hepatite, tanto no olho direito (p=0,0008 como esquerdo (p=0,0034. Os valores obtidos na medida da sensibilidade corneal dos pacientes infectados evidenciaram que a sensibilidade da córnea encontra-se alterada em comparação com a do grupo controle. O teste de cristalização do filme lacrimal não demonstrou diferenças entre ambos os grupos. Não houve correlação entre tempo de infecção pelo vírus e intensidade das alterações. CONCLUSÕES: Os resultados indicam que a hepatite C é causa de olho seco. Os mecanismos

  16. Selenium and ocular health in New Zealand.

    Science.gov (United States)

    Sheck, Leo; Davies, Jo; Wilson, Graham

    2010-06-11

    Selenium is an essential mineral and severe selenium deficiency is known to cause significant health problems. It has been well documented that New Zealand soil is low in selenium. Recent studies have addressed the roles of selenoproteins in the eyes, with evidence suggesting that selenium supplementation may have a role in preventing cataract formation and age-related maculopathy. This paper summarises the role of selenium in ocular and general health and discusses selenium supplementation in a New Zealand specific context.

  17. [Epstein Barr and cytomegaloviruses in ocular pathology].

    Science.gov (United States)

    Magdei, Corina; Cuşnir, Valeriu; Bârcâ, Ludmila

    2010-01-01

    Epstein-Barr virus (EBV) and Citomegalovirus (CMV) are Herpesviridae family representative and presents a real danger for human. A very high infect risk of population farther the danger The ocular pathology induced by them can affect all media and tunics of optic analyzer. An etiologic differentiation is necessary for the mentioned viruses induced diseases. The etiologic differentiation has like purpose the enforcement of an effective and optimal antiviral and immunomodulating therapy.

  18. Unusual ocular presentation of acute toxoplasmosis.

    Science.gov (United States)

    Willerson, D; Aaberg, T M; Reeser, F; Meredith, T A

    1977-01-01

    Four patients with toxoplasmosis are reported with unusual presenting ocular lesions. One patient had an active lesion that appeared to involve the optic nerve as well as focal toxoplasmosis chorioretinitis at the macula. A second patient had a pale optic nerve in association with the classical chorioretinal scars of toxoplasmosis. The third patient had toxoplasmosis chorioretinitis of the macula with subretinal neovascularisation. The fourth patient had a branch artery occlusion complicating acute retinitis. Images PMID:588525

  19. Ocular ultrasound findings in optic disk melanocytoma

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    Andrés Lisker-Cervantes

    2017-11-01

    Conclusion: Melanocytomas are small, benign tumors that are highly assessable by ocular ultrasound when their elevation surpasses 0.5 mm. In our study, the internal reflectivity ranged from high to very high, unlike other malignancies such as choroidal melanoma which tend to present with low internal reflectivity. The avascularity of the tumor is a common finding. Ultrasound is a remarkable tool that helps detect benign characteristics in a pigmented optic disk tumor and helps establish a more reliable diagnosis.

  20. Vitamin D in ocular and systemic health

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    Solani D. Mathebula

    2015-03-01

    Full Text Available Accumulated data supports the argument that vitamin D possesses several biological and molecular actions apart from its role in calcium absorption and facilitation of gene expression. Vitamin D deficiency has been an associated risk factor for cardiovascular disease,metabolic syndrome and ocular complications. The aim of this review is to summarise the most relevant data regarding these associations and to try to clarify whether, and to what extent, oral vitamin D supplementation could be used as a beneficial intervention in such diseases.Vitamin D is produced in skin exposed to sunlight UVB radiation and is then metabolised by the kidney into calciferol, which is an active form. The main function of vitamin D is to promote calcium and phosphorus absorption, and studies have shown that a lack of itplays an important role in ocular conditions, such as age-related macular degeneration and diabetic retinopathy. Recent studies have suggested that vitamin D may protect the diabetic retina; however, other vitamin D-associated conditions (diabetes, hypertension and cardiovascular diseases may result in secondary ocular manifestations and the potential forsight-threatening complications. The purpose of this review is to describe the current literature on the role of vitamin D in ocular and systemic wellness. However, more research is needed to determine if increasing levels of this vitamin can assist in preventing age-related macular degeneration or diabetic retinopathy. Since vitamin D is a circulating steroid hormone, its receptors are found in almost every cell in the human body, and this suggests that vitamin D might have a very broad role for overall health. However, there is still demand for further research to clarify the clinical use of vitamin D in the prevention and treatment of various chronic diseases.

  1. Trends in serious ocular trauma in Scotland.

    Science.gov (United States)

    Desai, P; Morris, D S; Minassian, D C; MacEwen, C J

    2015-05-01

    To report trends in serious, sight-threatening ocular trauma in Scotland. A prospective, population-based, observational study of patients with ocular trauma admitted to hospital in Scotland during a 12-month period (2008-2009), conducted through the British Ophthalmic Surveillance Unit. Data on circumstances of the injuries and visual outcomes were collected using protocols standardised to those from an earlier study (1991-1992) to allow direct comparisons over time. In all, 0.3% of all emergency admissions in Scotland were for ocular trauma. Significant differences were observed between the time periods in where an injury occurred (P=0.009): a reduction of those occurring in a sports/leisure facility (8.2%) and an increase in those occurring on the street (21.4%). Assaults remained the most common cause of injury (31%). Gender differences persisted with females more likely to have an injury from falls (OR=8.67; 95% CI: 2.41-31.49; P=0.002), or in the home (OR=5.40; 95% CI: 1.69-17.16; P=0.009 ), and less likely to have one in the workplace (P=0.06). Poor visual outcome was associated with injuries occurring in the home (OR=4.33, P=0.047), in a public place (OR=6.25, P=0.047), and those caused by a fall (OR 42.75, P<0.001); or assault (OR 7.29, P=0.019). Half of those with a poor outcome have no perception of light. Serious ocular trauma remains an infrequent, sight-threatening event, associated with significant monocular visual morbidity. The findings suggest a shift from corporate to personal responsibility for risk awareness, health, and safety.

  2. Adaptação de lentes de contato pós-trauma ocular Contact lens fitting after ocular trauma

    Directory of Open Access Journals (Sweden)

    Heryberto da Silva Alvim

    2003-08-01

    Full Text Available OBJETIVOS: Descrever os achados referentes à adaptação de lentes de contato nos casos de trauma ocular nos últimos 6 anos no Hospital São Geraldo, identificando os mecanismos dos traumas, os parâmetros das lentes de contato prescritas, e por fim avaliar quantitativamente a melhora da acuidade visual com o uso destas. MÉTODOS: Revisão dos prontuários de pacientes atendidos no Serviço de Lentes de Contato do Hospital São Geraldo nos últimos 6 anos. Os dados referentes à idade, sexo, diagnóstico, doenças associadas, olho acometido, acuidade visual pós-trauma, raio, curvatura e índice de permeabilidade ao oxigênio das lentes são descritos. RESULTADOS: O principal diagnóstico foi perfuração, com 25 casos (44,6%, o olho esquerdo estando acometido em 25 casos (58,2%. A AV pós-trauma corrigida mais freqüente foi 20/200 (20,9%. A AV corrigida média após o uso das lentes de contato foi de 20/20 (14%. O maior ganho em número de linhas na tabela de Snellen ocorreu em seis pacientes (14% (5 linhas. O diâmetro médio das lentes foi de 9,5 mm, o raio médio foi de 8,0 mm. A curvatura das lentes variou de 37,00 D a 52,75 D. A maioria das lentes tinha DK 71. A adaptação foi adequada em todos os casos. O intervalo médio entre o trauma e o início da adaptação foi de 3,5 anos. CONCLUSÃO: As lentes de contato são parte importante no tratamento tardio do trauma ocular, permitindo melhora significativa da AV na maioria dos casos.PURPOSE: To describe the findings related to contact lenses use after ocular trauma in the past 6 years at the São Geraldo Eye Hospital. We emphasize the improvement of visual acuity with contact lenses. METHODS: Chart review from the Contact Lens Service in the past 6 years. The information about age, gender, diagnosis, associated diseases, involved eye, pre- and post-trauma visual acuity, radius, curvature and of the lenses is described. RESULTS: The main diagnosis was ocular perforation, in 25 cases (44

  3. Management of severe ocular burns with symblepharon.

    Science.gov (United States)

    Shi, Weiyun; Wang, Ting; Gao, Hua; Xie, Lixin

    2009-01-01

    To evaluate the effect of lamellar keratoplasty combined with limbal stem cells, using amniotic membrane, autologous conjunctiva, and pseudopterygium to reconstruct external eyes for severe ocular burns with symblepharon. Thirty eyes of 29 patients had severe symblephara resulting from eye burns. According to the range of the symblepharon and the loss of limbal stem cells, partial lamellar keratoplasty combined with partial limbal stem cell treatment was performed in 19 eyes, and total lamellar keratoplasty with total limbus was performed in 11 eyes. All patients had amniotic membrane and autologous conjunctival transplantation, and the pseudopterygium was preserved to reconstruct the fornix. Symblephara were completely relieved in 19 eyes. They remained partially in ten eyes in strip-like form, but seven of these were completely relieved after further autologous conjunctival transplantation. One eye was treated with tarsorrhaphy for eyelid malformation. The remaining pseudopterygium became thinner after the operation and showed no symblepharon. Immune rejection occurred in eight corneal grafts; clarity was restored in four of these, while there was graft neovascularization in the remaining four. Depending on the area of symblepharon and the loss of limbal stem cells, partial or total lamellar keratoplasty combined with limbal stem cells, using amniotic membrane, autologous conjunctiva and pseudopterygium to reconstruct external eyes appears to be effective in treating severe ocular burns with symblepharon. Pseudopterygium can partly substitute autologous conjunctiva in ocular surface reconstruction.

  4. Platelet rich plasma in ocular surface.

    Science.gov (United States)

    Riestra, A C; Alonso-Herreros, J M; Merayo-Lloves, J

    2016-10-01

    The use of platelet-rich preparations has experienced a significant increase in recent years due to its role in tissue-repair and regeneration. The aim of this study is to examine the available evidence regarding the application of plasma rich in growth factors, and its variations, on the ocular surface. A review is also presented on the effects of platelet-derived growth factors, the implications of the preparation methods, and the existing literature on the safety and efficacy of these therapies in ocular surface diseases. Despite the widespread use of platelet preparations there is no consensus on the most appropriate preparation method, and growth factors concentration vary with different systems. These preparations have been used in the treatment of ocular surface diseases, such as dry eye or persistent epithelial defects, among others, with good safety and efficacy profiles, but further studies are needed to compare to the currently available alternatives. Copyright © 2016 Sociedad Española de Oftalmología. Published by Elsevier España, S.L.U. All rights reserved.

  5. Experimental models of autoimmune inflammatory ocular diseases

    Directory of Open Access Journals (Sweden)

    Fabio Gasparin

    2012-04-01

    Full Text Available Ocular inflammation is one of the leading causes of blindness and loss of vision. Human uveitis is a complex and heterogeneous group of diseases characterized by inflammation of intraocular tissues. The eye may be the only organ involved, or uveitis may be part of a systemic disease. A significant number of cases are of unknown etiology and are labeled idiopathic. Animal models have been developed to the study of the physiopathogenesis of autoimmune uveitis due to the difficulty in obtaining human eye inflamed tissues for experiments. Most of those models are induced by injection of specific photoreceptors proteins (e.g., S-antigen, interphotoreceptor retinoid-binding protein, rhodopsin, recoverin, phosducin. Non-retinal antigens, including melanin-associated proteins and myelin basic protein, are also good inducers of uveitis in animals. Understanding the basic mechanisms and pathogenesis of autoimmune ocular diseases are essential for the development of new treatment approaches and therapeutic agents. The present review describes the main experimental models of autoimmune ocular inflammatory diseases.

  6. Miastenia grave y miastenia grave ocular

    Directory of Open Access Journals (Sweden)

    Rosa María Naranjo Fernández

    Full Text Available La miastenia grave es una enfermedad caracterizada por debilidad y fatiga de los músculos voluntarios debido a una trasmisión anómala a nivel de la unión neuromuscular. La prevalencia es aproximadamente de 5 casos/100 000 personas. La miastenia grave puede ser bulbar, ocular o generalizada.Existen formas clínicas en la infancia como son la miastenia neonatal transitoria, la miastenia congénita y la miastenia juvenil. Los músculos oculares, faciales y bulbares son los más frecuentes afectados por la enfermedad. Cuando los síntomas se limitan a la musculatura cercana al ojo se denomina miastenia grave ocular. Una vez el oftalmólogo diagnostica o sospecha la miastenia grave, un neurólogo generalmente dirige la comprobación y tratamiento. El papel del oftalmólogo continúa siendo importante, además de chequear la motilidad y disfunción palpebral y proporcionar el alivio sintomático para estos desórdenes, debe estar alerta a la posibilidad de ambliopía.

  7. Ocular dominance and visual function testing.

    Science.gov (United States)

    Lopes-Ferreira, D; Neves, H; Queiros, A; Faria-Ribeiro, M; Peixoto-de-Matos, S C; González-Méijome, J M

    2013-01-01

    To show the distribution of ocular dominance as measured with sensory and eye sighting methods and its potential relationship with high and low contrast LogMAR visual acuity in presbyopic subjects. Forty-four presbyopes (48.5 ± 3.5 years) participated in this study. Ocular dominance was determined by eye sighting (hole-in-card) and sensorial (+1.50 D lens induced blur) methods. According to the dominance detected with each method (RE: right eye or LE: left eye), patients were classified in dominance type 1 (RE/RE), type 2 (RE/LE), type 3 (LE/RE) and type 4 (LE/LE). Baseline refractive error (MSE) was RE:-0.36 ± 1.67 D and LE:-0.35 ± 1.85 D (P = 0.930). RE was the dominant eye in 61.4% and 70.5% of times as obtained from sensorial and sighting methods, respectively. Most frequent dominance was of type 1 (52.3%), in this case the RE showed statistically significant better distance low contrast LogMAR VA (0.04 LogMAR units) compared to the LE (P eye sighting and sensorial methods to define ocular dominance agreed in more than half of cases. Amount of MSE was not significantly different between dominant and non-dominant eye. But in case of right dominance, the RE presented better distance low contrast VA compared to the LE.

  8. A uniform format for ocular imaging devices.

    Science.gov (United States)

    Ishikawa, H; Liebmann, J M; Uji, Y; Ritch, R

    1999-01-01

    To develop a uniform file format of ocular imaging data, including, but not limited to, ultrasound biomicroscopy, optical coherence tomography, and nerve fiber analyzer, capable of being transmitted via Internet or intranet for collaborative research and telemedicine use. File filters were developed as dynamic link libraries (DLLs). These can read the original raw data format of each ocular imaging device. A data file format was also designed to describe these raw data uniformly in three different types of compression: noncompressed, run length compression, and differential pulse code modulation (DPCM). These three file formats were then tested in the following aspects: file size, speed of reading, and speed of writing. Run length compression failed to compress raw data, while DPCM compressed raw data successfully (< or =35.5%). The speed of reading and writing files was slowest in DPCM. However, the actual time of reading and writing was fast enough (<0.6 s) for daily work regardless of file compression methods. The format designed has robust potential to be the standard file format for transmission of any ocular imaging raw data.

  9. PAEDIATRIC OCULAR TRAUMA IN KUCHING, SARAWAK, MALAYSIA

    Directory of Open Access Journals (Sweden)

    INTAN G

    2011-01-01

    Full Text Available Purpose: To evaluate the demography, aetiology, type and outcome of paediatric ocular trauma in tertiary centre in Malaysia. Method: We retrospectively studied 118 eyes from 117 patients over a period of 36 months (January 2006 to December 2008. All ocular injuries in patients aged 12 and below seen in the Ophthalmology Department for the first time were included in thisstudy. Results: Mean age of patients was 6.1±3.0 years. 68 cases (58.2% occurred in pre-school children, whereas 49 (41.9% in school-aged children. Boys accounted for 65.8% of cases. There was no predilection for either right or the left eye. 47% of cases (56 patients occurred in Malay. Most of the injuries took place at home when the children were alone (p<0.05. Sharp objects were the commonest cause (45 cases, 38.1%. The majority of cases (103, 87.3% were considered preventable. The frequency of open and closed globe injury was similar. Hyphema was more common in closed globe injury compared to open globe injury (p<0.05. Other associated injuries such as cataract, vitreous hemorrhage and retinal hemorrhage are similar between the two groups. Visual outcome is generally poor with only 34 eyes (28.8% had no visual impairment. Conclusion: Ocular trauma in children is an important cause of visual loss. Most cases occurred at home and were preventable. Prevention through education is the best approach.

  10. Ocular pathology in congenital heart disease.

    Science.gov (United States)

    Mansour, A M; Bitar, F F; Traboulsi, E I; Kassak, K M; Obeid, M Y; Megarbane, A; Salti, H I

    2005-01-01

    To describe the ocular findings in subjects with congenital heart disease (CHD). In a prospective study, the same observer examined 240 consecutive patients with CHD admitted to the medical centre. Two independent geneticists performed identification of syndromes. The commonest anatomic cardiac anomalies were ventricular or atrial septal defects (62), tetralogy of Fallot (39), pulmonary stenosis (25), and transposition of the great arteries (24). The heart lesions were divided physiologically into volume overload (90), cyanotic (87), and obstructive (63). In all, 105 syndromic subjects included the velocardiofacial syndrome (18), Down's syndrome (17), CHARGE association (6), DiGeorge syndrome (5), Williams syndrome (3), Edwards syndrome (3), Noonan syndrome (3), VACTERL association (2), and Patau syndrome (trisomy 13) (2). The paediatric team recognized 51 patients as syndromic. Two independent geneticists recognized additional 54 patients as syndromic. Positive eye findings were present in 55% (132) and included retinal vascular tortuosity (46), optic disc hypoplasia (30), trichomegaly (15), congenital ptosis (12), strabismus (11), retinal haemorrhages (8), prominent eyes (7), and congenital cataract (6). There was a strong correlation between the retinal vascular tortuosity and both a low haematocrit (P=0.000) and a low arterial oxygen saturation (P=0.002). Patients with CHD are at a high risk for ocular pathology and need screening for various ocular abnormalities.

  11. [Ocular movements and reading: a review].

    Science.gov (United States)

    Quercia, P

    2010-06-01

    A literature review of the important findings discovered over the past three decades on ocular movements during reading is presented herein. This fairly recent function in human evolution is a sophisticated sensorimotor and cognitive activity that brings very complex neurological and motor mechanisms into play. However, knowledge in this field is limited, even though reading problems are very common in children. We collected all the references in PubMed dating from 1969 to 2009 using the following "binocular coordination", "eye movements", "reading", and "dyslexia". When reading, the visual axes move in a very particular way, notably with regard to the parallelism of the ocular axes when saccades are triggered to reach the words to be read and during fixations, which enable decoding. In fact, when reading, the visual axes are often disassociated, even going as far as to intersect in a considerable number of cases. There are relatively few studies that have examined binocular coordination during reading. We are beginning to understand how the ocular axes move during horizontal saccades. Three-dimensional studies could be the next step to providing more precise data. Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.

  12. Ocular tissue engineering: current and future directions.

    Science.gov (United States)

    Karamichos, D

    2015-02-17

    Tissue engineering (TE) is a concept that was first emerged in the early 1990s to provide solutions to severe injured tissues and/or organs [1]. The dream was to be able to restore and replace the damaged tissue with an engineered version which would ultimately help overcome problems such as donor shortages, graft rejections, and inflammatory responses following transplantation. While an incredible amount of progress has been made, suggesting that TE concept is viable, we are still not able to overcome major obstacles. In TE, there are two main strategies that researchers have adopted: (1) cell-based, where cells are been manipulated to create their own environment before transplanted to the host, and (2) scaffold-based, where an extracellular matrix is created to mimic in vivo structures. TE approaches for ocular tissues are available and have indeed come a long way, over the last decades; however more clinically relevant ocular tissue substitutes are needed. Figure 1 highlights the importance of TE in ocular applications and indicates the avenues available based on each tissue.[...].

  13. Study of ocular aberrations with age.

    Science.gov (United States)

    Athaide, Helaine Vinche Zampar; Campos, Mauro; Costa, Charles

    2009-01-01

    Aging has various effects on visual system. Vision deteriorate, contrast sensitivity decreases and ocular aberrations apparently make the optical quality worse across the years. To prospective evaluate ocular aberrations along the ages. Three hundred and fifteen patients were examined, 155 were male (39.36%) and 160 were female (60.63%). Ages ranged from 5 to 64 year-old, the study was performed from February to November, 2004. Patients were divided into 4 age-groups according to IBGE (Instituto Brasileiro de Geografia e Estatística) classification: 68 patients from 5 to 14 year-old, 55 patients from 15 to 24 year-old, 116 from 25 to 44 year-old and 76 from 45 to 67 year-old. All patients had the following characteristics: best corrected visual acuity > 20/25, emmetropia or spherical equivalent < 3.50 SD, refractive astigmatism < 1.75 CD on cycloplegic refraction, normal ophthalmologic exam and no previous ocular surgeries. This protocol was approved by Federal University of São Paulo Institutional Review Board. Total optical aberrations were measured by H-S sensor LadarWave Custom Cornea Wavefront System (Alcon Laboratories Inc, Orlando, FLA, USA) and were statistically analysed. Corneal aberrations were calculated using CT-View software Version 6.89 (Sarver and Associates, Celebration, FL, USA). Lens aberrations were calculated by subtraction. High-order (0.32 e 0.48 microm) and ocular spherical aberrations (0.02 e 0.26 microm) increased respectively in child and middle age groups. High order (0.27 microm) and corneal spherical aberrations (0.05 microm) did not show changes with age. Lens showed a statistically significant spherical aberration increase (from -0.02 to 0.22 microm). Vertical (from 0.10 to -0.07 microm) and horizontal coma (from 0.01 to -0.12 microm) presented progressively negative values with aging. High-order and spherical aberrations increased with age due to lens contribution. The cornea did not affect significantly changes observed on ocular

  14. Ocular trauma resulting from paintball injury.

    Science.gov (United States)

    Pahk, Patricia J; Adelman, Ron A

    2009-04-01

    Paintball-related ocular injuries result in severe damage and loss of vision. Despite efforts to increase public awareness and improve safety features, the incidence of eye injuries has increased over time. We examined the characteristics and ocular effects of paintball injury at our tertiary referral center. Retrospective review of charts of patients with paintball injury between 1998-2005. Fourteen patients were evaluated for paintball injury; 13 (93%) were male and one (7%) was female. Average age was 17 years (range from 9 to 30). Thirteen patients (95%) did not wear eye protection; one is unknown. Injuries occurred while playing paintball in three patients (21%); ten (71%) were injured in either accidental (four patients) or intentional (six patients) shootings not associated with play. Minimum follow-up was 6 weeks, except for one patient who was lost to follow-up. Seven patients (50%) had final visual acuity (VA) better than 20/200, six patients (43%) were 20/200 or worse, and information on one patient was not available. VA, except in one case, improved with treatment. Decreased VA in this case was due to proliferative vitreoretinopathy (PVR). Hyphema was noted in ten patients (71%), vitreous hemorrhage in eight (57%), retinal hemorrhage in six (43%), retinal tear or detachment in six (43%), commotio retinae in six (43%), iris injury in five (36%), keratopathy in four (29%), lens injury in two (14%), subluxation of lens in two (14%), secondary glaucoma in two (14%), open globe/intraocular foreign body (IOFB) in one (7%), choroidal rupture in one (7%), and proliferative vitreoretinopathy (PVR) in one (7%). Ten patients (71%) required intervention (surgery, laser retinopexy or cryotherapy). Paintball trauma results in significant ocular injury and loss of vision. Most injuries occur in unsupervised settings without proper eye protection. Ten patients (71%) were injured in accidental or intentional shootings. Lack of supervision and use of paintball materials

  15. Dry Eye Management: Targeting the Ocular Surface Microenvironment

    Science.gov (United States)

    Zhang, Xiaobo; Jeyalatha M, Vimalin; Qu, Yangluowa; He, Xin; Ou, Shangkun; Bu, Jinghua; Jia, Changkai; Wang, Junqi; Wu, Han; Liu, Zuguo

    2017-01-01

    Dry eye can damage the ocular surface and result in mild corneal epithelial defect to blinding corneal pannus formation and squamous metaplasia. Significant progress in the treatment of dry eye has been made in the last two decades; progressing from lubricating and hydrating the ocular surface with artificial tear to stimulating tear secretion; anti-inflammation and immune regulation. With the increase in knowledge regarding the pathophysiology of dry eye, we propose in this review the concept of ocular surface microenvironment. Various components of the microenvironment contribute to the homeostasis of ocular surface. Compromise in one or more components can result in homeostasis disruption of ocular surface leading to dry eye disease. Complete evaluation of the microenvironment component changes in dry eye patients will not only lead to appropriate diagnosis, but also guide in timely and effective clinical management. Successful treatment of dry eye should be aimed to restore the homeostasis of the ocular surface microenvironment. PMID:28661456

  16. Roles of IL-10 in ocular inflammations: a review.

    Science.gov (United States)

    Ghasemi, Hassan; Ghazanfari, Tooba; Yaraee, Roya; Owlia, Parviz; Hassan, Zuhair Mohammad; Faghihzadeh, Soghrat

    2012-12-01

    This review represents the current in vitro, in vivo, animal and human investigations on the roles of IL-10 in ocular inflammatory conditions. The data sources were literature reviews, including Pub Med, Medline, and ISI databases (since 1989 to mid-2012). Search items were, IL-10, chemokines, cytokines, alone or in combination with, serum, aqueous, vitreous eye, ocular, ocular tissues, ophthalmic, and review. Ocular effects of IL-10 depend on the sources of the secretion and sites of the action. IL-10 plays important anti-inflammatory and especially anti-angiogenic activities in ocular tissues such as the conjunctiva, cornea, retina, choroid, and orbit. IL-10 plays major anti-inflammatory and anti-angiogenic roles in most of the ocular inflammations. Also, IL-10 plays a role in development of anterior chamber-associated immune deviation (ACAID). Any manipulation of IL-10 for treatment purposes should be considered very cautiously due to its potential hazards to the immune system.

  17. Perfil epidemiológico do trauma ocular penetrante antes e após o novo código de trânsito Epidemiological profile of penetrating ocular trauma before and after the new traffic code

    Directory of Open Access Journals (Sweden)

    Paulo Caldas Silber

    2002-08-01

    Full Text Available Objetivo: Comparar o perfil epidemiológico dos pacientes com trauma ocular penetrante (TOP antes e após a regulamentação do novo código de trânsito. Métodos: Estudo retrospectivo de 253 pacientes com TOP examinados na Seção de Trauma Ocular (UNIFESP de janeiro de 1997 a abril de 1999. Os pacientes foram divididos em dois grupos: Grupo I, pacientes com trauma ocular antes da implantação do novo código; Grupo II, história de trauma após sua implantação. Os pacientes foram avaliados em relação a diferentes aspectos do trauma e exame oftalmológico. Resultados: Os achados epidemiológicos em relação à idade, sexo e raça foram similares em ambos os grupos. No grupo I, os pacientes entre 21 e 50 anos apresentaram distribuição similar quanto à etiologia do trauma, ao passo que no grupo II, no mesmo intervalo de idade, predominaram os acidentes automobilísticos. Em relação ao uso do cinto de segurança, 60% e 92% dos pacientes não estavam usando o cinto, nos grupos I e II, respectivamente. 60% dos pacientes no grupo II mencionaram consumo de álcool, contra 40%, no grupo I. Conclusão: Apesar das medidas de impacto tomadas pelo governo para controlar os acidentes, os danos do trauma ocular continuam relacionados a fatores passíveis de prevenção, como o uso do cinto de segurança e consumo de álcool.Purpose: To study the epidemiologic profile of the patients with penetrating ocular trauma (POT before and after the application of the new traffic code. Methods: Retrospective study of 253 patients with POT examined at the Ocular Trauma Section (UNIFESP from January 1997 to April 1999. The patients were divided into 2 groups: Group I, patients with ocular trauma before the new traffic code; Group II, trauma history after the new code. The patients were evaluated regarding different aspects on trauma and ophthalmic evaluation. Results: The epidemiological findings regarding age, sex and race were similar in both groups. In

  18. Ocular burns in eye traumatology emphatically on chemical burns

    OpenAIRE

    Farský, Lukáš

    2008-01-01

    Burns to the sclera, conjunctiva, cornea, and eyelid are considered ocular burns. Ocular burn injuries are classified by etiologic agents as either chemical injuries (ie, acid, alkali) or radiant energy injuries (ie, thermal, ultraviolet). Chemical injuries to the eye represent one of the true ophthalmic emergencies. While almost any chemical can cause ocular irritation, serious damage generally results from either strongly basic (alkaline) compounds or acidic compounds. Alkali injuries are m...

  19. Paintball related ocular injuries: First case report in Saudi patients

    OpenAIRE

    Al-Amry, Mohammad; Al-Ghadeer, Huda

    2017-01-01

    Paintball is a popular recreational sport. This case series describes three Saudi patients exposed to paintball ocular injuries with sever ocular trauma. Two patients developed hyphema and traumatic cataract and one patient had vitreous hemorrhage, choroidal detachment, commotio retinae and retinal tear. All patients require surgical intervention. Final best corrected visual acuity was 20/200, 20/30 and 20/50 respectively. Paintball related ocular injuries can result in severe visual loss and...

  20. Ocular surface inflammation impairs structure and function of meibomian gland.

    Science.gov (United States)

    Mizoguchi, Shin; Iwanishi, Hiroki; Arita, Reiko; Shirai, Kumi; Sumioka, Takayoshi; Kokado, Masahide; Jester, James V; Saika, Shizuya

    2017-10-01

    Dysfunction of the meibomian glands alters secreted meibum quantitatively and qualitatively that can lead to damage to the ocular surface epithelium. In response to an unstable tear film cause by meibomian gland dysfunction, ocular surface epithelium is damaged and expresses inflammatory cytokines leading to secondary ocular inflammation. In turn, inflammatory disorders of the palpebral conjunctiva and lid margin may affect the structure and function of meibomian gland. The disorders include allergic conjunctivitis, long-term usage of contact lenses, dermatological diseases that affect conjunctival homeostasis, Stevens-Johnson's syndrome or chemical burning of the ocular surface and lid margin. Copyright © 2017. Published by Elsevier Ltd.

  1. Albinism: particular attention to the ocular motor system.

    Science.gov (United States)

    Hertle, Richard W

    2013-01-01

    The purpose of this report is to summarize an understanding of the ocular motor system in patients with albinism. Other than the association of vertical eccentric gaze null positions and asymmetric, (a) periodic alternating nystagmus in a large percentage of patients, the ocular motor system in human albinism does not contain unique pathology, rather has "typical" types of infantile ocular oscillations and binocular disorders. Both the ocular motor and afferent visual system are affected to varying degrees in patients with albinism, thus, combined treatment of both systems will maximize visual function.

  2. Ocular shell structures in some Cretaceous trachyleberid Ostracoda

    Science.gov (United States)

    Kontrovitz, M.; Puckett, T.M.

    1998-01-01

    This is the first study of internal ocular shell structures of Cretaceous ostracodes. Internal molds from eight species of four genera from Santonian, Campanian, and Maastrichtian strata revealed a stalked ocular sinus constricted along its length and distally inflated. The latter part has anterior and posterior lobes and a subcentral concavity. These Cretaceous trachyleberids have ocular shell structures similar to Cenozoic taxa and it is presumed they functioned similarly. However, each taxon has a diagnostic ocular sinus and an inner surface of the eye tubercle that distinguishes each from all other forms examined.

  3. Association between Exposure to Smartphones and Ocular Health in Adolescents.

    Science.gov (United States)

    Kim, Joowon; Hwang, Yunji; Kang, Seungheon; Kim, Minhye; Kim, Tae-Shin; Kim, Jay; Seo, Jeongmin; Ahn, Hyojeong; Yoon, Sungjoon; Yun, Jun Pil; Lee, Yae Lim; Ham, Hyunsoo; Yu, Hyeong Gon; Park, Sue K

    2016-08-01

    Smartphone use has dramatically increased in recent years. Smartphones may have adverse health effects, particularly on the eyes, because users stare at the screen for a much longer time than they do with ordinary mobile phones. The objective of this study was to elucidate the relationship between smartphone use and ocular symptoms among adolescents. Information on smartphone use and ocular symptoms (blurring, redness, visual disturbance, secretion, inflammation, lacrimation and dryness) related to eye fatigue and strain from 715 adolescent subjects from three cities in Korea was obtained using a structured questionnaire. Ocular health was scored using number of ocular symptoms. Odds ratios (ORs), 95% confidence intervals (95% CIs) and p-values for ocular symptoms were calculated with binomial and multinomial logistic regression models. Higher prevalence rates for ocular symptoms were observed in groups with greater exposure to smartphones (p smartphone use was associated with a higher likelihood of having multiple ocular symptoms (5-7 symptoms out of 7 symptoms; p = 0.005). Excessive/intermittent use (>2 hours daily and ≤2 hours continuously) and excessive/persistent use (>2 hours daily and >2 hours continuously) compared to shorter use (smartphones was associated with a higher likelihood of having multiple ocular symptoms (OR 3.05, 95% CI 1.51-6.19; p = 0.001). Increasing exposure to smartphones can have a negative impact on ocular health in adolescents.

  4. Ocular cicatricial pemphigoid masquerading as chronic conjunctivitis: a case report

    Directory of Open Access Journals (Sweden)

    DaCosta J

    2012-12-01

    Full Text Available Joanna DaCostaMoorfields Eye Hospital, London, UKAbstract: Conjunctivitis is often considered an innocuous condition which is self-limiting. This report describes misdiagnosis of ocular cicatricial pemphigoid as chronic conjunctivitis. Ocular cicatricial pemphigoid is a rare autoimmune condition. The clinical features which are useful to distinguish this condition from infective conjunctivitis are discussed. The investigation and treatment of ocular cicatricial pemphigoid is discussed. It is important to recognize nonocular symptoms and signs that may indicate the presence of a more serious underlying pathological condition necessitating specialized ophthalmic referral and subsequent investigation and treatment.Keywords: autoimmune, conjunctivitis, ocular cicatricial pemphigoid

  5. Estudo anatomohistopatológico da degeneração cística ovariana em fêmeas suínas submetidas a associação de gonadotrofinas exógenas e flushing alimentar

    OpenAIRE

    Aline Campos Rosseto

    2005-01-01

    O objetivo do estudo realizado no Laboratório de Pesquisa em Suínos e Laboratório de Oncologia Veterinária da Faculdade de Medicina Veterinária e Zootecnia da Universidade de São Paulo– FMVZ. USP, São Paulo – SP, foi verificar as degenerações císticas ovarianas e suas características histopatológicas de fêmeas tratadas com gonadotrofinas exógenas e flushing. Foram utilizadas 72 marrãs pré-púberes da linhagem Pen Ar Lan NAIMA®, com idade média de 157,49 ± 5,01 dias, e 96,65 ±...

  6. Representações sociais de enfermeiros sobre a religiosidade ao cuidar de pacientes em processo de morte

    Directory of Open Access Journals (Sweden)

    Fátima Maria da Silva Abrão

    2013-10-01

    Full Text Available Estudo qualitativo, ancorado na Teoria das Representações Sociais a partir do pensamento de Jodelet, realizado em uma Unidade de Terapia Intensiva e Oncologia de um hospital universitário. Objetivou-se compreender as representações sociais dos enfermeiros acerca da religiosidade ao cuidar de pacientes em processo de morte. Os dados foram coletados de maio a agosto de 2010, utilizando a técnica de Análise de Conteúdo de Bardin. As representações da religiosidade inseridas na prática do cuidar de pacientes em processo de morte valorizam as crenças dos profissionais sobre a morte, seu significado permitindo elaborar mecanismos de enfrentamento. Considera-se que a tomada de consciência se dará através da compreensão da realidade e da inserção da temática na discussão da qualidade da saúde e da capacitação dos profissionais.

  7. Profound retinal ischaemia after ranibizumab administration in an eye with ocular ischaemic syndrome

    DEFF Research Database (Denmark)

    Kofoed, Peter Kristian; Munch, Inger Christine; Larsen, Michael

    2009-01-01

    Abstract. Purpose: To report the result of ranibizumab administration in an eye with ocular ischaemic syndrome. Methods: Fluorescein angiography, ocular pneumoplethysmography and retinal vessel calibre measurement. Results: An 85-year-old man with ocular ischaemic syndrome demonstrated vision los...

  8. The impact of combined oral contraceptives on ocular tissues: a review of ocular effects

    Directory of Open Access Journals (Sweden)

    Marilita M. Moschos

    2017-10-01

    Full Text Available The aim of this manuscript is to review the action and adverse effects of combined oral contraceptives (COCs on ocular tissues. The percentage of unwanted pregnancies and the subsequent abortions make contraception crucial worldwide. Over 100 million women around the world use common contraceptive methods, including intrauterine devices, combined estrogen and progestin oral contraceptives, as well as progestin only preparations (oral contraceptives, implants or injections. COCs are widely used for contraception, but they are also indicated in menorrhagia, endometriosis, acne and hirsutism, fibroid uterus and premenstrual syndrome. However, they have been associated with high rates of cardiovascular events, venous thromboembolic disease, ischemic strokes and breast cancer. The incidence of COCs-related ocular complications is estimated to be 1 in 230 000, including dry eye symptoms, corneal edema, lens opacities and retinal neuro-ophthalmologic or vascular complications. We may infer that the serious ocular complications of COCs can be prevented by eliminating the estrogen dosage and choosing third-generation progestins. In any case, doctors should take into consideration the systemic and ocular history of the patients before selecting any method of contraception.

  9. Ocular Motor Function in Children with Spastic Hemiplegia Evaluated by the Ocular Motor Score.

    Science.gov (United States)

    Rydberg, A; Ygge, J; Olsson, M

    2017-09-01

    To assess the ocular motor functions in children with spastic hemiplegia by using the Ocular Motor Score (OMS). This study included 34 children, median age 11 years. The children were divided into 3 groups according to the underlying brain lesion; group 1 malformations, group 2 white matter damage of immaturity (WMDI), and group 3 cortical/subcortical lesions. The OMS protocol consists of 15 different subtests evaluating ocular motor functions. The OMS is divided into 2 parts, a static and a dynamic. The results from each subtest are scored 0, 0.3, 0.5, or 1, according to the level of disturbance, where 0 corresponds to normal function and 1 represents the maximum disability in the certain subtest. A total OMS (tOMS) between 0 and 15 can be obtained. The median tOMS in the whole spastic hemiplegia group was 2.5 (range 1.3-5.8). The highest median tOMS 5.2 was seen in group 1, in the children with malformations. Strabismus was found in 45% (15/34) of the children, with an equal percentage in all 3 groups. The children with spastic hemiplegia had a median tOMS of 2.7 and the highest median tOMS was seen in children with malformations. The OMS protocol is easy to use clinically and gives a quick overview of the patient´s ocular motor functions.

  10. Rehabilitación en pacientes con trauma ocular Rehabilitation of ocular trauma patients

    Directory of Open Access Journals (Sweden)

    Eduardo Ariel Ramos Gómez

    2012-01-01

    Full Text Available La rehabilitación en oftalmología tiene como función fundamental lograr el máximo aprovechamiento posible del resto visual. El traumatismo ocular es considerado una de las entidades nosológicas frecuentes que conllevan a una rehabilitación visual. Las causas que provocan este tipo de trauma son variadas y dentro de estas, las agresiones con intención de provocar daños con secuelas son muy frecuentes. Es objetivo de esta revisión puntualizar la importancia de la rehabilitación en pacientes con traumatismo ocular e incentivar el buen accionar de todos los oftalmólogos en cuanto a su atención.The main goal of rehabilitation in ophthalmology is to use as much as possible the residual vision. Ocular trauma is considered one of the common diseases that imply visual rehabilitation. The causes of eye injuries are varied; among them assaults with intent to cause damage are the most common. The objective of this article was to point out the importance of rehabilitation in patients with ocular trauma and to encourage all the ophthalmologists to act accordingly.

  11. Glaucoma in patients with ocular chemical burns.

    Science.gov (United States)

    Lin, Michelle P; Ekşioğlu, Ümit; Mudumbai, Raghu C; Slabaugh, Mark A; Chen, Philip P

    2012-09-01

    To examine the development and management of glaucoma in patients with ocular chemical burns. Retrospective, observational case series. setting: University of Washington Eye Clinics. patient population: Twenty-nine eyes (18 patients) with ocular chemical burns seen between 1997 and 2010 with a minimum of 3 months of follow-up. observation procedure: Eyes were graded using the Roper-Hall scale. main outcome measures: Long-term use of glaucoma medications (3 months or more) and need for glaucoma surgery. The mean age was 45 ± 17 years, with a mean follow-up of 75 ± 47 months (median, 66 months). Roper-Hall grade III or IV eyes (n = 20) had significantly higher intraocular pressure at presentation (35.9 vs 16.4 mm Hg; P = .001) and over follow-up were more likely to require long-term glaucoma medications (P = .003) or to undergo glaucoma surgery (P = .016) than Roper-Hall grade I or II eyes. Thirteen eyes (12 Roper-Hall grade III or IV) underwent glaucoma surgery. Eight eyes underwent glaucoma tube implant surgery; 4 required at least 1 revision. Seven eyes underwent diode laser cyclophotocoagulation; 4 required repeat treatment. Most (89%) eyes had controlled intraocular pressure at the last follow-up. However, 76% of eyes with visual acuity of 20/200 or worse at initial evaluation did not have improved vision at the last follow-up. Eyes with Roper-Hall grade III or IV ocular chemical burns were more likely to have glaucoma and to require surgery for it. Outcomes of glaucoma management generally were good, although tube implant surgeries often had complications requiring revision. Copyright © 2012 Elsevier Inc. All rights reserved.

  12. Parstatin Suppresses Ocular Neovascularization and Inflammation

    Science.gov (United States)

    Huang, Hu; Vasilakis, Panagiotis; Zhong, Xiufeng; Shen, Ji-Kui; Geronatsiou, Katerina; Papadaki, Helen; Maragoudakis, Michael E.; Gartaganis, Sotirios P.; Vinores, Stanley A.

    2010-01-01

    Purpose. Parstatin is a 41-mer peptide formed by proteolytic cleavage on activation of the PAR1 receptor. The authors recently showed that parstatin is a potent inhibitor of angiogenesis. The purpose of the present study was to evaluate the therapeutic effect of parstatin on ocular neovascularization. Methods. Choroidal neovascularization was generated in mice using laser-induced rupture of Bruch's membrane and was assessed after 14 days after perfusion of FITC-dextran. Oxygen-induced retinal neovascularization was established in neonatal mice by exposing them to 75% O2 at postnatal day (P)7 for 5 days and then placing them in room air for 5 days. Evaluation was performed on P17 after staining with anti-mouse PECAM-1. The effect of parstatin was tested after intravitreal administration. The effects of subconjunctival-injected parstatin on corneal neovascularization and inflammation in rats were assessed 7 days after chemical burn-induced corneal neovascularization. Retinal leukostasis in mice was assessed after perfusion with FITC-conjugated concanavalin A. Results. Parstatin potently inhibited choroidal neovascularization with an IC50 of approximately 3 μg and a maximum inhibition of 59% at 10 μg. Parstatin suppressed retinal neovascularization with maximum inhibition of 60% at 3 μg. Ten-microgram and 30-μg doses appeared to be toxic to the neonatal retina. Subconjunctival parstatin inhibited corneal neovascularization, with 200 μg the most effective dose (59% inhibition). In addition, parstatin significantly inhibited corneal inflammation and VEGF-induced retinal leukostasis. In all models tested, scrambled parstatin was without any significant effect. Conclusions. Parstatin is a potent antiangiogenic agent of ocular neovascularization and may have clinical potential in the treatment of angiogenesis-related ocular disorders. PMID:20538980

  13. Ocular Dominance and Visual Function Testing

    Directory of Open Access Journals (Sweden)

    D. Lopes-Ferreira

    2013-01-01

    Full Text Available Purpose. To show the distribution of ocular dominance as measured with sensory and eye sighting methods and its potential relationship with high and low contrast LogMAR visual acuity in presbyopic subjects. Method. Forty-four presbyopes (48.5 ± 3.5 years participated in this study. Ocular dominance was determined by eye sighting (hole-in-card and sensorial (+1.50 D lens induced blur methods. According to the dominance detected with each method (RE: right eye or LE: left eye, patients were classified in dominance type 1 (RE/RE, type 2 (RE/LE, type 3 (LE/RE and type 4 (LE/LE. Results. Baseline refractive error (MSE was RE:−0.36 ± 1.67 D and LE:−0.35 ± 1.85 D (P=0.930. RE was the dominant eye in 61.4% and 70.5% of times as obtained from sensorial and sighting methods, respectively. Most frequent dominance was of type 1 (52.3%, in this case the RE showed statistically significant better distance low contrast LogMAR VA (0.04 LogMAR units compared to the LE (P<0.05. Conclusions. The dominance was more frequent in RE in this sample. The eye sighting and sensorial methods to define ocular dominance agreed in more than half of cases. Amount of MSE was not significantly different between dominant and non-dominant eye. But in case of right dominance, the RE presented better distance low contrast VA compared to the LE.

  14. Ocular Munchausen syndrome resulting in bilateral blindness.

    Science.gov (United States)

    Salvo, M; Pinna, A; Milia, P; Carta, F

    2006-01-01

    Münchausen syndrome is a factitious disorder in which patients knowingly harm themselves for subconscious psychological reasons in order to be hospitalized. Recognition of this psychopathology is important, to prevent potentially severe eye damage. Ocular Münchausen syndrome is uncommon. The authors describe an elderly woman with recurrent, probably self-induced, ocular trauma leading to bilateral blindness. The authors are unaware of any previously reported cases of Münchausen syndrome resulting in bilateral blindness and occurring in old age. A 73-year-old woman was first seen in 1991 with a closed-globe injury to the right eye, apparently following a household fall. Physical examination showed no sign of extraocular trauma. Right visual acuity was 20/30 after 2 months. She was readmitted in May 2003 with left globe rupture, allegedly following a domestic fall. No extraocular trauma was found. She developed ocular phthisis 6 months postoperatively. The patient was admitted again in February 2004 with right globe rupture, following another alleged domestic fall. Physical examination showed no sign of extraocular trauma. Right visual acuity was 20/400 2 months postoperatively. Psychiatric evaluation revealed Münchausen syndrome. Psychotherapy was prescribed, but refused by her family. Diagnosis of Münchausen syndrome is difficult to make in the ophthalmic department. Münchausen patients have little or no ability to control their self-destructive behavior. A sympathetic and supportive approach is therefore required and these patients should be urgently referred to a psychiatrist with experience in factitious disorders. Even with psychotherapy, which is often refused, the prognosis remains poor.

  15. Buccal Epithelium in treating Ocular Surface Disorders

    Directory of Open Access Journals (Sweden)

    Srinivas KR

    2008-11-01

    Full Text Available Background - Ocular surface disorders due to limbal stem cell deficiency are an important cause of ocular morbidity and visual loss. Although autologous limbal stem cell transplants have helped in the management of unilateral disease, allografts in those with bilateral disease often fail due to immunological reasons. The use of autologous buccal epithelium cultivated on amniotic membrane has been described as a useful approach in the management of this condition. It is the purpose of this study to explore the feasibility of using a novel thermo-gelatin polymer (TGP as a substrate to culture these cells, and to characterize them using RNA extraction and RT-PCR. Methods - Oral cheek mucosal biopsies were obtained from 5 adult patients undergoing Modified Osteo-Odonto Keratoprosthesis surgery. The specimens were transported to the laboratory in transport medium. The cells were released using enzymatic digestion and seeded in both convention culture medium and TGP. The resulting cellular growth was characterized using RNA extraction and RT-PCR. Results - Cells could be cultured from 4 of the 5 specimens. In one specimen, contamination occurred and this was discarded. In the other specimens, the cheek epithelial cells could be cultured in both the conventional culture medium and TGP, with equal ease. RT-PCR revealed the presence of K3, a marker for epithelial cells, and GAPDH indicating the presence of some adipose tissue as well. Conclusions - It is possible to culture autologous cheek mucosal epithelial cells using TGP, a synthetic scaffold, without the need for other biological substrates. Since the specimens are obtained from the oral cavity, stringent asepsis is required. Further studies are required for histopathological characterization of the cultured cells and to create a model for delivery onto the ocular surface of eyes with bilateral surface disease due to limbal stem cell deficiency.

  16. Ocular safety of Viagra, (sildenafil citrate).

    Science.gov (United States)

    Laties, A M; Fraunfelder, F T

    1999-01-01

    To date, sildenafil citrate (Viagra) gives every evidence of being a safe drug for the eye despite a series of expressed concerns. A review of how its ocular safety profile has been identified offers insights into the strengths and weaknesses of present systems and resources for judging the ocular safety of Viagra or, for that matter, of any new drug. Such insights include: The great value of careful, informed assessment of preclinical information gleaned from laboratory experiments. By and large, such assessments point the way toward appropriate clinical evaluation. For Viagra, early in its development it was noted that besides exerting a major inhibitory effect on the intended target, the vascular-associated enzyme phosphodiesterase 5 (PDE5), the drug also exerts a lesser but definite inhibitory effect on the closely related PDE6, located in the retina. For this reason, preclinical evaluation of the drug included electroretinography plus postmortem histology. In addition, an extended eye examination was incorporated into clinical protocols. The often chaotic but invaluable information stream that becomes available once marketing approval has been gained and large populations begin to use a drug. False alarms, misattribution, and erroneous information are the order of the day. Nevertheless, as information accumulates, patterns of response clarify and the true nature of special susceptibility for subpopulations, if any, becomes apparent. A role for the astute clinician remains: Subtle changes or unusual risks for subpopulations can be missed entirely for long periods of time. A manifest need for improvement in evaluation of postmarketing side-effects. This need has led to the establishment of a new discipline: pharmacoepidemiology. In ophthalmology, the National Registry of Drug Induced Ocular Side-Effects maintains a constant and invaluable surveillance. Examples are supplied to illustrate each of these major points: Our presentation will include data gleaned from

  17. Serological IgG avidity test for ocular toxoplasmosis

    Directory of Open Access Journals (Sweden)

    Suresh S

    2012-01-01

    Full Text Available Subramaniam Suresh1, Saidin Nor-Masniwati1, Muhd Nor Nor-Idahriani1, Wan-Hitam Wan-Hazabbah1, Mohamed Zeehaida2, Embong Zunaina11Department of Ophthalmology, 2Department of Medical Microbiology and Parasitology, School of Medical Sciences, Universiti Sains Malaysia, Kelantan, MalaysiaBackground: The purpose of this study was to evaluate the immunoglobulin (Ig G avidity of serological toxoplasmosis testing in patients with ocular inflammation and to determine the clinical manifestations of ocular toxoplasmosis.Methods: A retrospective review of all patients presenting with ocular inflammation to the Hospital Universiti Sains Malaysia, Kelantan, Malaysia between 2005 and 2009 was undertaken. Visual acuity, clinical manifestations at presentation, toxoplasmosis antibody testing, and treatment records were analyzed.Results: A total of 130 patients with ocular inflammation were reviewed retrospectively. The patients had a mean age of 38.41 (standard deviation 19.24, range 6–83 years. Seventy-one patients (54.6% were found to be seropositive, of whom five (3.8% were both IgG and IgM positive (suggestive of recently acquired ocular toxoplasmosis while one (0.8% showed IgG avidity ≤40% (suggestive of recently acquired ocular toxoplasmosis and 65 patients (50.0% showed IgG avidity >40% (suggestive of reactivation of toxoplasmosis infection. Chorioretinal scarring as an ocular manifestation was significantly more common in patients with seropositive toxoplasmosis (P = 0.036. Eighteen patients (13.8% were diagnosed as having recent and/or active ocular toxoplasmosis based on clinical manifestations and serological testing.Conclusion: Ocular toxoplasmosis is a clinical diagnosis, but specific toxoplasmosis antibody testing helps to support the diagnosis and to differentiate between reactivation of infection and recently acquired ocular toxoplasmosis.Keywords: ocular toxoplasmosis, chorioretinal scar, toxoplasmosis antibody, IgG avidity test

  18. The prevalence of ocular surface complaints in Brazilian patients with glaucoma or ocular hypertension

    Directory of Open Access Journals (Sweden)

    Vital Paulino Costa

    2013-08-01

    Full Text Available PURPOSE: To examine the prevalence of ocular surface complaints in Brazilian patients with glaucoma or ocular hypertension who used topical intraocular pressure (IOP-lowering regimens. METHODS: In this multicenter, noninterventional, single-visit study, adults with glaucoma or ocular hypertension treated with an IOP-lowering regimen were administered the 12-item ocular surface disease index (OSDI questionnaire. Each response was scored on a 5-point scale, with 0 indicating symptom present none of the time and 4 indicating symptom present all of the time. The average of the 12 item responses for each patient was transformed to a scale from 0 to 100, with higher scores representing worse disabilities. OSDI results then were categorized as absence of OSD (scores of 0-12, mild OSD (scores of 13-22, moderate OSD (scores of 23-32, or severe OSD (scores of 33100. RESULTS: The 173 enrolled patients had a mean age of 61.2 years, were women in 65.3% of cases, and had glaucoma in 89.0% of cases and ocular hypertension in 11.0% of cases. OSDI scores for 158 patients using 1 IOP-lowering therapy indicated no OSD in 37.3% of patients (59/158, mild OSD in 20.9% (33/158, moderate OSD in 17.1% (27/158, and severe OSD in 24.7% (39/158. For the 120 patients using 1 IOP-lowering medication and having a known duration of diagnosis of glaucoma or ocular hypertension, mean OSDI scores were numerically higher (worse for the 39 patients with a diagnosis ≥6 years long (score 25 [± 20], indicating moderate OSD than for the 81 patients with a diagnosis lasting <6 years (score 22 [± 20], indicating mild OSD; however, no significant differences in OSDI scores by duration of diagnosis were evident in means (P=0.49, distributions (P≥0.26, or correlation (P=0.77. CONCLUSIONS: A large proportion of Brazilian patients treated with 1 IOP-lowering therapy had some ocular surface complaints.

  19. Ocular cells and light: harmony or conflict?

    Science.gov (United States)

    Jurja, Sanda; Hîncu, Mihaela; Dobrescu, Mihaela Amelia; Golu, Andreea Elena; Bălăşoiu, Andrei Theodor; Coman, Mălina

    2014-01-01

    Vision is based on the sensitivity of the eye to visible rays of the solar spectrum, which allows the recording and transfer of visual information by photoelectric reaction. Any electromagnetic radiation, if sufficiently intense, may cause damages in living tissues. In a changing environment, the aim of this paper is to point out the impact of light radiation on ocular cells, with its phototoxicity potential on eye tissues. In fact, faced with light and oxygen, the eye behaves like an ephemeral aggregate of unstable molecules, like a temporary crystallization threatened with entropia.

  20. Cine magnetic resonance imaging of ocular motility.

    Science.gov (United States)

    Cadera, W; Viirre, E; Karlik, S

    1992-01-01

    We describe a technique of generation of a cine motion picture of ocular movements in a patient with Duane Type II exotropia. With the magnetic resonance scanning unit, multiple scans can be sequenced to give a graphic animation to the eyes as targets are fixated across the visual field. With this technique, we were able to clearly view the contractility of the extraocular muscles and note the changes in pulling directions of the muscles in this patient. The restriction of movement due to the cocontraction of the horizontal rectus muscles was readily apparent.

  1. Penetrating ocular trauma from trampoline spring.

    Science.gov (United States)

    Spokes, David; Siddiqui, Salina; Vize, Colin

    2010-02-01

    The case is presented of a 12-year old boy who sustained severe penetrating ocular trauma while playing on a domestic trampoline. A main spring broke under tension and the hook had struck the eye at high velocity and penetrated the sclera. Primary repair was undertaken but on review it became apparent the eye could not be salvaged. Evisceration was carried out and an orbital implant was placed. Post-operative cosmesis is acceptable. This type of injury has not been reported before. Adult supervision of children on trampolines is recommended to minimise the chance of serious injury.

  2. Ocular aberrations in barn owl eyes.

    Science.gov (United States)

    Harmening, Wolf M; Vobig, Michael A; Walter, Peter; Wagner, Hermann

    2007-10-01

    Optical quality in barn owl eyes is presented in terms of measuring the ocular wavefront aberrations with a standard Tscherning-type wavefront aberrometer under natural viewing conditions. While accommodative state was uncontrolled, all eyes were focused within 0.4D with respect to the plane of the aberrometer. Total RMS wavefront error was between 0.06 and 0.15 microm (mean: 0.10 microm, STD: 0.03 microm, defocus cancelled) for a 6 mm pupil. The results suggest that image quality in barn owl eyes is excellent.

  3. [The ocular manifestations in systemic lupus erythematosus].

    Science.gov (United States)

    Gheorghiu, M

    1996-01-01

    Retinal involvement in systemic lupus erythematosus is dominated by a microangiopathy of unknown aetiology, with occlusive consequences. Although cases of severe retinal ischaemia have been recently described, from a statistic point of view, the occlusive phenomena seem to have declined over the last decades, under the influence of a better therapy and follow-up of the disease. The relatively high incidence of papilloedema and the fact that this oedema might be unilateral or asymptomatic are pointed out. The importance of ophthalmic examination in patients with SLE-like syndromes or in seronegative cases of SLE is revealed. Other ocular manifestation of the disease are reviewed.

  4. Fabrication of a custom ocular prosthesis.

    Science.gov (United States)

    Sethi, Tania; Kheur, Mohit; Haylock, Colin; Harianawala, Husain

    2014-01-01

    Defects of the eye may follow removal of a part of or the entire orbit. This results in the patient becoming visually, esthetically and psychologically handicapped. Restoring the defect with a silicone- or acrylic-based prosthesis not only restores esthetics but also gives back the lost confidence to the patient. This is a case report of a patient with a 'pthisical eye' and details the steps in fabrication of an ocular prosthesis. Particular attention has been given to the laboratory process in this technique to minimize the residual monomer content in the artificial eye.

  5. Irritation of ocular tissue by irreversible hydrocolloids.

    Science.gov (United States)

    Moergeli, J R; Fraleigh, E M; Ostrowski, J S; Pelleu, G B

    1985-08-01

    Two ophthalmic and two dental irreversible hydrocolloid materials were tested on rabbit conjunctivae to determine histologically their potential to irritate these tissues. Each of the four impression materials elicited nearly the same amount of inflammatory response. The differences between the response of the controls and the response to Ophthalmic Mold-Eye, Jelset Special Formula, and Kerr Alignate Type II were significant. These results indicate that certain dental irreversible hydrocolloids may be used for ocular prostheses but that they should be used with caution because of the inflammation caused by irreversible hydrocolloids.

  6. Involvement of Nrf2 in Ocular Diseases

    Directory of Open Access Journals (Sweden)

    Shehzad Batliwala

    2017-01-01

    Full Text Available The human body harbors within it an intricate and delicate balance between oxidants and antioxidants. Any disruption in this checks-and-balances system can lead to harmful consequences in various organs and tissues, such as the eye. This review focuses on the effects of oxidative stress and the role of a particular antioxidant system—the Keap1-Nrf2-ARE pathway—on ocular diseases, specifically age-related macular degeneration, cataracts, diabetic retinopathy, and glaucoma. Together, they are the major causes of blindness in the world.

  7. Circumstance and outcome of ocular paintball injuries.

    Science.gov (United States)

    Greven, Craig M; Bashinsky, Alice L

    2006-02-01

    To determine the circumstance and outcome of ocular injuries attributable to paintball projectiles. Retrospective interventional case series. Institutional review board approved retrospective chart review of 19 consecutive eyes with paintball injuries with minimum follow-up of 3 months. Ten eyes (53%) had final visual acuity of 20/40 or better, while seven (36%) were 20/200 or worse. Ten eyes were injured in paintball games, (two formal and eight informal), while nine (47%) were injured by accidents or assaults not associated with any "game." Paintball injuries often cause severe and permanent visual loss. Nearly half of these injuries occur outside a war game setting as accidents or assaults.

  8. Blunt Ocular Trauma Associated with Paintball Gun

    Directory of Open Access Journals (Sweden)

    Yavuz Özpınar

    2013-04-01

    Full Text Available A 21-year-old male patient presented to our hospital with a blunt paintball trauma to his left eye. The patient had corneal edema, traumatic cataract, traumatic mydriasis, and secondary glaucoma in his left eye. After corneal edema resolved, cataract surgery was performed. Because of uncontrolled intraocular pressure despite antiglaucoma medications, an Ahmed glaucoma valve was implanted. In the postoperative period, the patient’s visual acuity was 1/10. Paintball-related ocular injuries can be severe and visually devastating. (Turk J Ophthalmol 2013; 43: 135-7

  9. Curvature sensor for ocular wavefront measurement.

    Science.gov (United States)

    Díaz-Doutón, Fernando; Pujol, Jaume; Arjona, Montserrat; Luque, Sergio O

    2006-08-01

    We describe a new wavefront sensor for ocular aberration determination, based on the curvature sensing principle, which adapts the classical system used in astronomy for the living eye's measurements. The actual experimental setup is presented and designed following a process guided by computer simulations to adjust the design parameters for optimal performance. We present results for artificial and real young eyes, compared with the Hartmann-Shack estimations. Both methods show a similar performance for these cases. This system will allow for the measurement of higher order aberrations than the currently used wavefront sensors in situations in which they are supposed to be significant, such as postsurgery eyes.

  10. Ocular response analyser measurements and central corneal thickness in ocular rosacea patients.

    Science.gov (United States)

    Palamar, Melis; Degirmenci, Cumali; Ertam, Ilgen; Yagci, Ayse

    2017-02-01

    Rosacea is a chronic cutaneous disorder which is known to cause inflammation and increased proteolytic activity on the ocular surface that might lead to corneal biomechanical alterations. The aim of this study is to evaluate the corneal biomechanical properties of ocular rosacea patients and compare the measurements with healthy individuals as measured with Reichert ocular response analyser (ORA). Besides full eye examination [best corrected visual acuity (BCVA), intraocular pressure (IOP) measured with Goldmann applanation tonometry (IOP-G)], central corneal thickness (CCT), and ORA [corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated IOP (IOPcc), Goldmann correlated IOP (IOPg)] measurements of 30 eyes of 15 ocular rosacea patients (study group) and 30 eyes of 15 healthy individuals (control group) were performed. For comparisons paired t test was used. Mean age of study group was 45.26 ± 11.65 (range 25 and 63) and control group was 45.00 ± 8.91 (range 26 and 58) years (p = 0.865). No significant difference in BCVA, CCT, IOP-G, IOPcc was detected among groups. However, IOPg, CH, and CRF in the study group were significantly lower than in the control group (p = 0.013, p = 0.013, p = 0.009, respectively). IOPg, CH, and CRF parameters of ocular rosacea patients were significantly lower than normal individuals. These differences and their probable clinical reflections that might effect making decisions in conditions such as glaucoma should be investigated in larger number of patients.

  11. Clinical application of ocular trauma score for mechanical ocular injury in armed forces

    Directory of Open Access Journals (Sweden)

    Ying ZHANG

    2011-10-01

    Full Text Available Objective To evaluate the predictive value of ocular trauma score(OTS in mechanical ocular injuries occurring in military forces,and compare the difference of OTS application between ocular injury caused by military training and non-military training.Methods The data of 633 inpatients from armed forces suffering from injury of 665 eyes were retrospectively reviewed.Of the 665 injured eyes,326 were injured during military training and 339 during non-military training.The likelihood of final visual acuity(VA calculated with the OTS score was compared with that by the present OTS study,and the correlation between the score and final VA was then analyzed.Results Compared with the distribution of final VA in standard OTS score,the ratio in category 1 was statistically different in present study(P 0.05.There were significant differences in ratio of category 3 between eyes injured by military and non-military training(P < 0.05,and both ratios in category 1 were significantly different compared with those in standard OTS(P < 0.01,e.g.the ratio of NLP was lower(50% vs 73%,P < 0.01;43% vs 73%,P < 0.01;and the ratio in category 2 was significantly different between the eyes injured by non-military training and standard OTS(P < 0.05.However,the OTS showed positive correlation with final VA in present study(P < 0.0001.Conclusion OTS calculated at initial examination may primarily provide a piece of prognostic information of mechanical ocular injuries,and is of special benefit for deciding a prompt management or for evacuation decision for severe ocular injuries caused by military training.

  12. Visual Impairment and Ocular Findings among Deaf and Hearing ...

    African Journals Online (AJOL)

    Visual Impairment and Ocular Findings among Deaf and Hearing Impaired School Children in Central Region, Ghana. ... The overall prevalence of visual impairment was 5.8% among hearing impaired school children in the Central Region of Ghana. ... Keywords: Disability, eye, ear, refractive error, ocular deviation .

  13. Ocular Injuries: Another Example of the Heavy Prize of Terrorism ...

    African Journals Online (AJOL)

    Injuries to the face and ocular structures could occur at the war front not only to the enemies, but also to unsuspecting friends of the security agents. We report here a case of ocular injury involving an air force personnel (lance corporal) who was mistakenly hit on the face by the back blast of a rocket‑propelled grenade shot ...

  14. Astute and safe use of topical ocular corticosteroids in general ...

    African Journals Online (AJOL)

    Corticosteroids are an effective treatment for ocular inflammation, but they must be used with caution. Corticosteroids are the most effective way to treat ocular inflammation. They relieve symptoms rapidly and often prevent permanent damage. These medications, however, must be used with caution, as use of ...

  15. bilateral orbito-ocular gunshot injury in a nigerian male

    African Journals Online (AJOL)

    Orbito-ocular injuries with retained intra-orbital foreign bodies affecting both orbits are uncommon in civilian practice. This case report aims to highlight an unusual presentation of bilateral orbito-ocular injury with retained intra-orbital foreign bodies following accidental explosion of a locally fabricated dane gun.

  16. Post Operative pain following Ocular Surgery: Relevant Preventitive ...

    African Journals Online (AJOL)

    Objective: To determine the optimal time and mode of administration of postoperative analgesics following ocular surgery. Background: Most elective ocular surgery are said to be accompanied by onlymild pain. This knowledge, however, is not available to the prospective patientand this usually results in undue fear of eye ...

  17. Airbag related ocular injuries: a short case series | Onakoya ...

    African Journals Online (AJOL)

    Airbags are designed to protect occupants of motor vehicles from injuries in the event of a crash but have been implicated in some serious ocular injuries after road traffic accidents (RTAs). Diagnosis of airbag related ocular injuries requires a high index of suspicion. Using a retrospective hospital‑based, noninterventional ...

  18. A retrospective study of ocular neoplasms in Benin City, Nigeria ...

    African Journals Online (AJOL)

    Ocular neoplasm is one of the least investigated ocular disorders in Nigeria. Although relatively rare, they play a role in causing blindness and even death in adults and children. In this study, the records of all patients/seen at the eye clinic and specimen received at the histopathology department of the University of Benin, ...

  19. Ocular problems among public service retirees in a Southern ...

    African Journals Online (AJOL)

    Materials and Methods: Participants were retired public servants who consented to ocular examinations at their pension pay points in Port Harcourt during the 2012 World Sight Day. Visual acuity, ocular examinations including fundoscopy and intraocular pressure measurements were recorded and subsequently analyzed ...

  20. Ocular Problems Among Public Service Retirees in a Southern ...

    African Journals Online (AJOL)

    to ocular examinations at their pension pay points in Port Harcourt during the 2012 World Sight Day. Visual acuity, ocular examinations including fundoscopy and intraocular pressure measurements were recorded and subsequently analyzed using. Statistical Package for Social Sciences version 20. Results: Five hundred ...

  1. Pattern of ocular morbidity among children seen in a Nigerian ...

    African Journals Online (AJOL)

    This is because a delay in treatment for some causes of childhood blindness can lead to amblyopia. Furthermore, the number of “blind years” resulting from ... Refractive error (19.5%) was the most common ocular morbidity seen, followed by ocular trauma (13.1%), allergic conjunctivitis (11.1%) and cataract (10.9%).

  2. Pattern of Ocular Pathologies Diagnosed with B-scan ...

    African Journals Online (AJOL)

    biometry for calculation of optical power of artificial lens implants is another advantage of ocular .... Loss of vision. 8. 8. Photopsia. 3. 3. Bangal, et al.: Pattern of ocular pathologies diagnosed with B-scan ultrasonography. Nigerian Journal of Ophthalmology ¦ Jul-Dec 2016 ¦ Volume 24 ¦ Issue 2. 73. [Downloaded free from ...

  3. Epidemiology, Pathophysiology, and the Future of Ocular Toxoplasmosis

    NARCIS (Netherlands)

    Kijlstra, A.; Pedersen, E.

    2014-01-01

    Despite large advances in the field of ocular toxoplasmosis, large gaps still exist in our knowledge concerning the epidemiology and pathophysiology of this potentially blinding infectious disease. Although ocular toxoplasmosis is considered to have a high health burden, still little is known about

  4. Long term ocular and neurological involvement in severe congenital toxoplasmosis

    NARCIS (Netherlands)

    Meenken, C.; Assies, J.; van Nieuwenhuizen, O.; Holwerda-van der Maat, W. G.; van Schooneveld, M. J.; Delleman, W. J.; Kinds, G.; Rothova, A.

    1995-01-01

    This study was set up to determine the long term ocular and systemic sequelae in patients with severe congenital toxoplasmosis. Cross sectional and retrospective study of 17 patients with severe congenital toxoplasmosis. In addition to chorioretinitis (100%), the most common abnormal ocular features

  5. Implementing and applying the Ocular Trauma Score: the challenges

    Directory of Open Access Journals (Sweden)

    Desirée C Murray

    2016-01-01

    Full Text Available Ocular trauma is a significant cause of unilateral blindness in the Caribbean in both adults and children. In Trinidad and Tobago, blunt ocular injury will typically account for around a third of all referrals from the Accident and Emergency department to the ophthalmology unit.

  6. Utilization of ocular safety devices among Sawmill workers in Nigeria

    African Journals Online (AJOL)

    Ocular examination was done on site with a pen torch, portable hand-held slit lamp bio-microscope and direct ophthalmoscope. ... Conclusion: There is need to safeguard the ocular health of sawmill workers in Nigeria by provision of eye safety devices, health education of the workers on the benefits of its use and ...

  7. Clinical Evaluation of Ocular Antiviral Effect of Garcinia Kolanut ...

    African Journals Online (AJOL)

    Clinical Evaluation of Ocular Antiviral Effect of Garcinia Kolanut Water Extract in Epidemic Haemorrhagic Keratoconjunctivitis in Lagos. ... Critical awareness and preventive measures are usually applied. These infections are ... They all used only the sterile Garcinia kolanut water extract as drops for their ocular complaints.

  8. Ocular changes in pregnant Nigerian women | Ebeigbe | Nigerian ...

    African Journals Online (AJOL)

    Objective: Pregnancy results in a lot of hormonal changes in the body and the eyes are no exception. These ocular changes could be physiologic, pathologic or a modification of a pre-existing condition. The aim of this study was to determine physiologic ocular changes that are associated with pregnancy in healthy Nigerian ...

  9. Ocular Hazards in Ophthalmic Dispensing Industry in South East ...

    African Journals Online (AJOL)

    The prevalence of ocular hazards in ophthalmic dispensing industry in south east Nigeria was carried out using 70 subjects drawn from different towns in the region. Tables were used to analyze the data obtained from his study. Results showed that ocular hazards are involved in ophthalmic dispensing depending on the ...

  10. uptake of ocular surgeries at ebonyi state university teaching hospi

    African Journals Online (AJOL)

    Dr Chijioke Onyeknowu

    Conclusion: The yearly surgical uptake at EBSUTH was low and cataract extraction was the most common ocular surgery performed. Key words: ocular surgeries, analysis, EBSUTH, Abakaliki. INTRODUCTION. The eye clinic of Ebonyi State University Teaching Hospital. (EBSUTH), Abakaliki was revitalized and equipped ...

  11. Hutchinson's sign as a marker of ocular involvement in HIVpositive ...

    African Journals Online (AJOL)

    Background. A positive Hutchinsonfs sign indicates an increased risk of ocular involvement in herpes zoster ophthalmicus (HZO). We examined the sensitivity of Hutchinsonfs sign as an indicator of ocular involvement in a consecutive series of patients presenting with HZO. Methods. We conducted a descriptive ...

  12. Epidemiological Survey of Paediatric Ocular Morbidity in North ...

    African Journals Online (AJOL)

    Vernal disease was the commonest ocular morbidity seen constituting 349 cases (40.3%), ocular trauma 152 (17.6%), infective conjunctivitis 106 (12.3%) and refractive errors 89 (10.2%). The location of industries (rice mills, sawmills, cement factory) away from residential areas, availability of antiallergic drugs must be ...

  13. uptake of ocular surgeries at ebonyi state university teaching hospi

    African Journals Online (AJOL)

    Dr Chijioke Onyeknowu

    SUMMARY. Objective: To ascertain the number, types and frequencies of ocular surgeries done at Ebonyi State University Teaching. Hospital (EBSUTH), Abakaliki, with a view to improving the overall surgical uptake. Methods: A retrospective review of ocular surgeries done at. EBSUTH between January 2003 and April ...

  14. Orbito-Ocular Tumours In Nigerian Children | Onwasigwe ...

    African Journals Online (AJOL)

    Conclusion: This study has brought to light the many aspect of orbito-ocular tumours in Nigerian children and also highlighted the many problems caused by inadequate facilities for diagnosis and management. Key words: Orbito-ocular tumours, children, retinoblastoma, tumour sites. [Jnl College of Medicine Vol.7(2) 2002: ...

  15. Ocular morbidity pattern in Abonnema, Akuku–Toru local ...

    African Journals Online (AJOL)

    Background: Ocular morbidity patterns are indicative of the ocular health status of communities. They are significant pointers to the prevalent and emerging eye diseases in any country. The absence of professional eye care services in most Nigerian villages has necessitated the use of eye camps offering free ...

  16. Ocular Uveitis as the Initial Presentation of Syphilis

    Directory of Open Access Journals (Sweden)

    May-Ching Hong

    2007-07-01

    Conclusion: Syphilis can be presented initially as ocular uveitis without obvious systemic manifestation. Ophthalmologists play an important role in the early diagnosis and treatment of syphilis. If treated early enough, the response is good, even if the patient is allergic to penicillin. Awareness of the multiple manifestations of ocular syphilis is the key to early detection of the disease.

  17. Canine ocular cryptococcosis: a case report

    OpenAIRE

    Larsson, C.E.; M. Otsuka; Michalany,N.S.; Barros,P.S.M.; W. Gambale; A.M.V. Safatle

    2003-01-01

    Descreve-se, pela primeira vez no Brasil, um caso de criptococose canina com acometimento oftalmo e dermatopático, com diagnóstico intra-vitam, em animal da raça Pastor Alemão, fêmea, com 24 meses de vida, criado em São Paulo, em contacto com outros cinco cães assintomáticos, que havia se infectado pelo contato com dejetos de pombos (Columba livia). Evoluia há 90 dias, com quadro tegumentar e ósseo, sintomas e lesões características, sendo, ainda, detectada forma assintomática de coriorretini...

  18. Immunopathology in ocular toxoplasmosis: facts and clues

    Directory of Open Access Journals (Sweden)

    Justus G Garweg

    2009-03-01

    Full Text Available Although parasite-mediated host cell lysis is deemed to be an important cause of tissue destruction in ocular toxoplasmosis (OT, the severity of the disease is probably correlated with hypersensitivity and inflammation. Notwithstanding, the mechanisms that regulate the inflammatory process in recurrent OT are poorly understood. Recent evidence has identified interleukin (IL 17 as a marker for disease severity. The ocular and cerebral presence of this cytokine is generally associated with the induction of autoimmune responses in the brain and the eye. Indeed, there are indications that autoimmunity may contribute to clinical variability in the activity of OT. IL-23, which induces the proliferation of IL-17-producing cells and IL-27, which is a counterplayer to IL-17, may regulate T(H-1-cell-mediated responses in OT. The importance of these cytokines in experimental models of uveitis and encephalitis has been recently reported. CD25(+ regulatory T-cells may control the local inflammatory response and protect the host against collateral inflammatory tissue damage. The responses of these cells to OT may be suitably tailored to cope with either an acquired or a congenital aetiology. Knowledge relating to immunoreactivity in OT has grown impressively during the past few years. Its characteristic and variable features have been identified and the potential relevance of autoimmunity has been assessed. In light of this knowledge, potential future treatment options have been considered.

  19. Describing ocular aberrations with wavefront vergence maps.

    Science.gov (United States)

    Nam, Jayoung; Thibos, Larry N; Iskander, D Robert

    2009-05-01

    A common optometric problem is to specify the eye's ocular aberrations in terms of Zernike coefficients and to reduce that specification to a prescription for the optimum sphero-cylindrical correcting lens. The typical approach is first to reconstruct wavefront phase errors from measurements of wavefront slopes obtained by a wavefront aberrometer. This paper applies a new method to this clinical problem that does not require wavefront reconstruction. Instead, we base our analysis of axial wavefront vergence as inferred directly from wavefront slopes. The result is a wavefront vergence map that is similar to the axial power maps in corneal topography and hence has a potential to be favoured by clinicians. We use our new set of orthogonal Zernike slope polynomials to systematically analyse details of the vergence map analogous to Zernike analysis of wavefront maps. The result is a vector of slope coefficients that describe fundamental aberration components. Three different methods for reducing slope coefficients to a spherocylindrical prescription in power vector forms are compared and contrasted. When the original wavefront contains only second order aberrations, the vergence map is a function of meridian only and the power vectors from all three methods are identical. The differences in the methods begin to appear as we include higher order aberrations, in which case the wavefront vergence map is more complicated. Finally, we discuss the advantages and limitations of vergence map representation of ocular aberrations.

  20. Effects of chalazion excision on ocular aberrations.

    Science.gov (United States)

    Sabermoghaddam, Ali A; Zarei-Ghanavati, Siamak; Abrishami, Mojtaba

    2013-06-01

    The goal of this study was to compare higher-order aberrations before and after upper lid chalazion excision. Fourteen eyes from 12 patients (8 females, mean age: 28.7 ± 2.7 years) with upper lid chalazion were enrolled in this prospective interventional case series. Chalazia were excised by standard transconjunctival vertical incision. Ocular aberrations were evaluated by aberrometry (ZyWave) before and 2 months after chalazion excision. Root mean square of total higher-order aberrations decreased from 0.67 ± 0.12 to 0.43 ± 0.15 μm (P = 0.012) after excision. The root mean square of Zernike orders in the vertical and horizontal trefoil and horizontal coma were decreased after excision. Orbscan IIz tomography showed a statistically significant decrease in 5 mm zone irregularity (P = 0.027) and an increase in minimum simulated keratometry after surgery (P = 0.046). Chalazion increases higher-order aberrations, as measured by the Hartmann-Shack aberrometer, which could affect the preoperative evaluation and results of refractive surgery, especially wavefront-guided approaches. Chalazion excision could reduce ocular aberrations and is recommended before refractive surgeries.

  1. Ocular Straylight with Different Multifocal Contact Lenses.

    Science.gov (United States)

    Łabuz, Grzegorz; López-Gil, Norberto; van den Berg, Thomas J T P; Vargas-Martín, Fernando

    2017-04-01

    Multifocal contact lenses have been growing in popularity as a modality to correct presbyopic eyes, although visual side effects such as disability glare have been reported. The objective of this study was to investigate the effect of multifocal contact lenses on disability glare by means of ocular straylight. A prospective randomized, comparative study was performed that included 16 subjects free of ocular pathology. Straylight was measured using a commercial straylight meter with the natural and dilated pupil. Participants were fitted with Proclear Multifocal (Distance/Near), ACUVUE Oasys for Presbyopia, and Air Optix Aqua Multifocal randomized to the left or right eye. Straylight measurements were repeated with the contact lens in situ after the pupil dilation. Results obtained with the dilated pupil without contact lens acted as a control. Diameter of the natural and dilated pupil was 2.87 ± 0.40 mm and 7.45 ± 0.86 mm, respectively (P lenses, a significant difference was only found between Air Optix and the control group (P = .006). The latter showed also slightly increased light scatter. A difference in measured straylight was found between the studied multifocal lenses. The observed variability and the straylight-pupil size dependency should be taken into account to avoid elevated straylight in multifocal contact lens wearers. The reason for the observed differences in straylight must be the subject of future studies.

  2. Ocular toxoplasmosis in immunosuppressed nonhuman primates

    Energy Technology Data Exchange (ETDEWEB)

    Holland, G.N.; O' Connor, G.R.; Diaz, R.F.; Minasi, P.; Wara, W.M.

    1988-06-01

    To investigate the role of cellular immunodeficiency in recurrent toxoplasmic retinochoroiditis, six Cynomolgus monkeys (Macaca fascicularis) with healed toxoplasmic lesions of the retina were immunosuppressed by total lymphoid irradiation. Three months prior to irradiation 30,000 Toxoplasma gondii organisms of the Beverley strain had been inoculated onto the macula of eye in each monkey via a pars plana approach. Toxoplasmic retinochoroiditis developed in each animal, and lesions were allowed to heal without treatment. During total lymphoid irradiation animals received 2000 centigrays (cGy) over a 7-week period. Irradiation resulted in an immediate drop in total lymphocyte counts and decreased ability to stimulate lymphocytes by phytohemagglutinin. Weekly ophthalmoscopic examinations following irradiation failed to show evidence of recurrent ocular disease despite persistent immunodeficiency. Four months after irradiation live organisms were reinoculated onto the nasal retina of the same eye in each animal. Retinochoroidal lesions identical to those seen in primary disease developed in five of six animals. Toxoplasma organisms therefore were able to proliferate in ocular tissue following the administration of immunosuppressive therapy. This study fails to support the hypothesis that cellular immunodeficiency alone will initiate recurrent toxoplasmic retinochoroiditis. Results suggest that reactivation of disease from encysted organisms involves factors other than suppression of Toxoplasma proliferation. If reactivation occurs by other mechanisms, however, cellular immunodeficiency then may allow development of extensive disease.

  3. Treatment of ocular toxocariasis with albendazole.

    Science.gov (United States)

    Barisani-Asenbauer, T; Maca, S M; Hauff, W; Kaminski, S L; Domanovits, H; Theyer, I; Auer, H

    2001-06-01

    The purpose of this study was to evaluate the efficacy of combined albendazole and steroid treatment for uveitis caused by Toxocara canis in immunocompetent patients. Five patients (7 eyes) with ocular larva migrans syndrome (OLM) were used in this study. Toxocariasis was suspected based on clinical manifestations and confirmed by anti-toxocara IgG and Western blot analysis. Systemic albendazole (adults: 800 mg b.i.d.; children: 400 mg b.i.d.) was given in conjunction with steroids. Visual acuity before and after therapy, inflammatory response, side effects and toxicity were evaluated. Treatment resulted in an improved visual acuity in all patients. Mean initial Snellen visual acuity was 20/40, and mean final acuity was 20/20. There were no recurrences of uveitis throughout the observation period (average: 13.8 months; range: 3 days to 24 months). These findings suggest that albendazole, in combination with systemic steroids, is a useful regimen to treat ocular larva migrans syndrome.

  4. Nanoliposomal minocycline for ocular drug delivery

    Science.gov (United States)

    Kaiser, James M.; Imai, Hisanori; Haakenson, Jeremy K.; Brucklacher, Robert M.; Fox, Todd E.; Shanmugavelandy, Sriram S.; Unrath, Kellee A.; Pedersen, Michelle M.; Dai, Pingqi; Freeman, Willard M.; Bronson, Sarah K.; Gardner, Thomas W.; Kester, Mark

    2012-01-01

    Nanoliposomal technology is a promising drug delivery system that could be employed to improve the pharmacokinetic properties of clearance and distribution in ocular drug delivery to the retina. We developed a nanoscale version of an anionic, cholesterol-fusing liposome that can encapsulate therapeutic levels of minocycline capable of drug delivery. We demonstrate that size extrusion followed by size-exclusion chromatography can form a stable 80-nm liposome that encapsulates minocycline at a concentration of 450 ± 30 μM, which is 2% to 3% of loading material. More importantly, these nontoxic nanoliposomes can then deliver 40% of encapsulated minocycline to the retina after a subconjunctival injection in the STZ model of diabetes. Efficacy of therapeutic drug delivery was assessed via transcriptomic and proteomic biomarker panels. For both the free minocycline and encapsulated minocycline treatments, proinflammatory markers of diabetes were downregulated at both the messenger RNA and protein levels, validating the utility of biomarker panels for the assessment of ocular drug delivery vehicles. PMID:22465498

  5. Physiotherapy in brest cancer: life quality and function clinical evolution Fisioterapia em oncologia mamária: qualidade de vida e evolução clínico funcional

    OpenAIRE

    Verônica Baptista Frison; Felipe Pereira Zerwes; Caroline Helena Lazzarotto de Lima; Mara Regina Knorst; Gabriela Tomedi Leites

    2010-01-01

    Purpose: to assess physiotherapy intervention impact on quality of life and functional evolution of women who underwent clinical treatment of breast cancer. Methods: almost-experimental study of the type before and after, carried out from March to June of 2009. We have included 10 patients subjected to surgical treatment of breast cancer and who underwent adjuvant treatment. We performed functional evaluation and a quality life questionnaire application, and a intervention protocol proposal w...

  6. Ocular components before and after acquired, nonaccommodative esotropia.

    Science.gov (United States)

    Frane, S L; Sholtz, R I; Lin, W K; Mutti, D O

    2000-12-01

    Acquired nonaccommodative esotropia describes the sudden onset of a constant, comitant strabismus of idiopathic origin in children >6 months of age. We present a case of acquired nonaccommodative esotropia at 20 months of age in a subject participating in the Berkeley Infant Biometry Study, a longitudinal study of emmetropization and ocular component development in infants between 3 months and 3 years of age. Ocular components for this child were normal before the onset of strabismus (within 2 SD's of the mean for orthotropic study participants) for refractive error, corneal power, lens radii, lens power, and ocular axial dimensions. Refractive error postsurgically was significantly more hyperopic and crystalline lens power lower than average at +2.38 D and 37.2 D, respectively. The lack of abnormal ocular parameters is consistent with the idiopathic etiology of acute onset esotropia. This case suggests that ocular component values may not be useful for assessing the risk of acquired nonaccommodative esotropia.

  7. Ocular trauma from paintball-pellet war games.

    Science.gov (United States)

    Mason, John O; Feist, Richard M; White, Milton F

    2002-02-01

    We studied ocular injuries and visual outcome after blunt trauma from paintball pellets. We retrospectively reviewed cases of ocular injury from paintball pellets occurring over 32 months. Ten cases of ocular injury from paintball pellets were recorded. Most patients (9) were injured at home or at a friend's home; only 1 was injured at a war game facility. Six patients had surgery. Final visual acuity was 20/25 or better in 6 patients, 20/30 to 20/50 in 2 patients, 20/60 to 20/100 in 2 patients, and 20/200 in 1 patient. Traumatic maculopathy and epiretinal membrane formation were determinants of worse final visual acuity. Paintball pellet ocular injuries occur more frequently at home than at war game facilities. Advanced surgical techniques offer decreased ocular morbidity and improved visual acuity. Decreasing visual morbidity from paintball pellets requires public education, proper product labeling, and packaging of eye protection with all paintball-related products.

  8. A case of severe airbag related ocular alkali injury.

    Science.gov (United States)

    Barnes, Shawn S; Wong, William; Affeldt, John C

    2012-08-01

    While airbags have saved many lives and are clearly beneficial overall, sodium hydroxide (NaOH) powder produced by the inflation reaction can cause significant alkali ocular injury if not irrigated promptly. Here we report a case of severe airbag related ocular alkali injury as a way to bring attention to the need for prompt ocular irrigation following motor vehicle accidents (MVA) with airbag deployment. A 47-year-old man was involved in a MVA with airbag deployment in a rural setting. Attention was paid to several other life-threatening traumatic injuries, however, ocular irrigation was not performed until some 6-7 hours after the MVA. Over the course of 6 months, airbag related alkali injury caused severe limbal ischemia, conjunctivalization of the cornea, corneal epithelial defects, cicatricial scarring, haze, and corneal/limbal vascularization despite amniotic membrane graft. Awareness of the importance of ocular irrigation following airbag deployment must be raised both in the ophthalmology and emergency medicine communities.

  9. Lagochilascariasis leading to severe involvement of ocular globes, ears and meninges Infecção humana por Lagochilascaris minor com envolvimento ocular, auditivo e das meninges

    Directory of Open Access Journals (Sweden)

    Renata T.R. Aquino

    2008-12-01

    Full Text Available A case report of a 31 year-old woman from Paraíba State (North-Eastern Brazil that presented severe involvement of ocular globes, ears and meninges. Diagnosis was established after enucleation of her left eye, when adult worms were seen in the midst of a granulomatous inflammatory process. Her response to the initial treatment with levamisole and cambendazole was good, but there was a relapse after the fifth month of treatment even with maintenance doses of both medications. She later received ivermectin and albendazol and responded well.Paciente do sexo feminino, com 31 anos, procedente da Paraíba, apresentava envolvimento severo de ambos os globos oculares, com perda da visão à esquerda, comprometimento da audição e das meninges. Após enucleação do olho esquerdo fragmento de helminto identificado como Lagochilascaris minor foi observado em processo inflamatório granulomatoso. Inicialmente a paciente foi tratada com levamisol e cambendazol, com bom resultado. Verificou-se, todavia, piora do quadro após cinco meses, com eliminação de larvas do ascarídeo em lesão presente na órbita esquerda, embora a medicação fosse mantida com administração periódica. Houve boa resposta terapêutica, com regressão do quadro, após substituição dos anti-helmínticos anteriores pela associação ivermectina e albendazol.

  10. Anomalias oculares e características genéticas na síndrome de Marfan

    Directory of Open Access Journals (Sweden)

    Sallum Juliana Maria Ferraz

    2002-01-01

    Full Text Available Objetivo: Para se identificar as alterações oculares presentes na síndrome de Marfan, este trabalho apresenta a avaliação oftalmológica de 46 indivíduos portadores desta doença. Métodos: Estudo prospectivo com avaliação clínica de 46 pacientes portadores de síndrome de Marfan com avaliação oftalmológica completa. Dezessete pacientes também foram submetidos a exame genético clínico e estudo molecular. Resultados: Dos quarenta e seis pacientes incluídos neste estudo, as seguintes alterações oculares foram encontradas com maior freqüência: subluxação do cristalino (67,3%, hipoplasia de íris (23,9%, descolamento de retina (7,6%, córnea plana (2,2%, megalocórnea (2,2% e miopia ou astigmatismo miópico (34,8%. Cinco pacientes (10,9% apresentaram exame ocular normal em ambos os olhos. Detectou-se uma mutação patogênica distinta das relatadas na literatura em uma paciente, uma mutação de sentido trocado que ocorreu no éxon 28 levando à mudança de aminoácido C1166Y. Conclusões: As alterações oculares da síndrome de Marfan são freqüentes e o conhecimento do gene responsável FBN-1 e de sua expressão no olho auxiliam para o diagnóstico e tratamento destas anomalias.

  11. Distrofia oftalmoplégica progressiva. Forma de inicio ocular precoce e comprometimento muscular universal tardio Progressive ophthalmoplegic dystrophy

    Directory of Open Access Journals (Sweden)

    João P. Rodrigues

    1968-03-01

    Full Text Available É estudada uma forma particular de distrofia muscular progressiva — forma óculo-faríngea — cujo diagnóstico foi comprovado mediante traçados eletromiográficos e biópsia do músculo orbicular da pálpebra. São analisadas as duas formas de distrofias oftalmoplégicas: 1 miopatia ocular; 2 miopatia óculo-faríngea. A forma óculo-faríngea é mais rara, incide em idades mais avançadas (média de 40 anos em comparação com a forma ocular pura (média de 23 anos; além disso, é ressaltada a alta incidência familiar daquela forma de miopatia. O caso ora registrado parece ser um élo entre as duas formas, pois o início foi precoce, sem incidência familiar e com comprometimento da deglutição e de músculos da face, pescoço, tronco, cintura escapular, pélvica e dos membros.A case of peculiar form of progressive muscular dystrophy — the oculopharyngeal one — is reported. The diagnosis was ascertained by electromiography and biopsy of orbicularis palpebrae muscle. Two forms of ophthalmoplegic dystrophy are analysed: 1 ocular myopathy and 2 oculopharyngeal miopathy. The latter is less frequent, occurring on patients in the fourth decade, in comparison with the pure ocular form affecting patients in the second decade. Besides this, the high familial incidence of the oculo-pharyngeal form is stressed. The reported case seems to be an intermediate form between them. The onset occurred at 11 years of age; there was no other case in the family, the disease involving swallowing, face, neck, trunk, shoulder, pelvic and members muscles.

  12. Early and late complications of ocular burn injuries.

    Science.gov (United States)

    Cabalag, Miguel S; Wasiak, Jason; Syed, Quaderi; Paul, Eldho; Hall, Anthony J; Cleland, Heather

    2015-03-01

    Ocular involvement in facial burns may lead to significant long-term morbidity. The aims of this study were to analyse the epidemiology, management and outcomes of ocular burn injuries, as well as to identify risk factors for developing early and late ocular complications. A retrospective medical chart review was conducted for 125 patients with ocular burns who were admitted to the Victorian Adult Burns Service (VABS), from November 2000 to January 2010. Univariate analyses was utilised to identify demographic and injury related variables associated with early and late complications. The majority of patients were male (n=101, 80.8%), and the mean (range) age was 40.7 (15-86) years. The most common mechanism was flame burns (n=77, 61.6%), and most were accidental (n=114, 91.2%). Early ocular complications occurred in 50 (40.0% [95% CI: 31.3%-49.1%]) patients, with the commonest being visual loss (n=39, 31.2%). Chemical burns, ocular discomfort, peri-orbital oedema, corneal injury, as well as eyelid and facial burns of increasing severity were associated with developing an early complication. Late ocular complications occurred in 19 (15.2% [95% CI: 9.4%-22.7%]) patients, with visual loss being the most frequent (n=13, 10.4%). Chemical burns, ocular discomfort, corneal injury of increasing severity, visual loss on presentation, ectropion, as well as eyelid burns of increasing depth were associated with late morbidity. Chemical burns, ocular discomfort, as well as corneal injury and eyelid burns of increasing severity were risk factors for both early and late ocular complications. III (retrospective comparative study). Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.

  13. PROFILE OF OCULAR TRAUMA IN UTTARAKHAND, A HOSPITAL BASED STUDY.

    Directory of Open Access Journals (Sweden)

    Renu Dhasmana

    2013-01-01

    Full Text Available Background: Although ocular trauma is preventable public health problem throughout the world it is still one of the common causes of ophthalmic morbidity and monocular blindness. There are no published studies on pattern and severity of ocular trauma in Uttarakhand. The present study analyzes the pattern and visual outcome of ocular trauma in this region. Methods: Study design: Prospective hospital-based study. Settings: Patients of ocular trauma presenting to Ophthalmology OPD and emergency department of Himalayan Institute of Medical Sciences, Dehradun. Participants: All ocular injury patients seen for the first time during the period January to December 2008. Results: A total of 88 patients, and 103 eyes, were studied. Men had two fold higher rate of ocular injury than women. The mean age of presentation was 31.2 + 13.6 years (range: 6 - 80 years. The predominant age group of patients was 21-40 years, 55.29 % (n = 47. Eye injuries related to road traffic accident were seen in 37.86% of eyes. Industrial workers were more frequently involved in ocular trauma (23.86%. Closed globe injuries were noted in 55 eyes (53.39% and open globe injuries were noted in 40 eyes (38.83%. Eight eyes (7.76% suffered from chemical injuries. The initial presenting visual acuity of patients with blunt ocular trauma was better than penetrating injury. Eye with better visual acuity at presentation had better visual prognosis at 6 months. Conclusion: Ocular injuries were common in young males. Road traffic accidents related eye injuries were noted in significant number of cases. Strict implementation of traffic rules, health education and preventive strategies may help to decrease the occurrence of ocular injuries.

  14. Padronização das atividades em centro cirúrgico oncológico segundo a Classificação das Intervenções de Enfermagem

    Directory of Open Access Journals (Sweden)

    Joao Francisco Possari

    2013-06-01

    Full Text Available Este estudo teve como objetivos identificar em um centro cirúrgico especializado em oncologia, as atividades de enfermagem realizadas no período transoperatório, classificar e validar as atividades em intervenções, segundo a Classificação das Intervenções de Enfermagem (NIC. O levantamento das atividades foi realizado por meio dos registros e da observação direta da assistência de enfermagem, nos quatro turnos de trabalho. As atividades foram classificadas em intervenções de enfermagem da NIC utilizando-se a técnica mapeamento cruzado. O elenco de intervenções foi validado por profissionais de enfermagem, em oficinas de trabalho. Identificaram-se 49 intervenções: 34 de cuidados diretos e 15 de cuidados indiretos. O reconhecimento das intervenções de enfermagem permite medir o tempo despendido na sua execução, variável fundamental para quantificar e qualificar a carga de trabalho dos profissionais de enfermagem.

  15. Proptose ocular como manifestação clínica de tumores malignos extra-orbitários: estudo pela tomografia computadorizada

    Directory of Open Access Journals (Sweden)

    Baptista Ana Célia

    2003-01-01

    Full Text Available Doenças sistêmicas, doenças orbitárias primárias e lesões extra-orbitárias com extensão secundária para a órbita podem causar proptose ocular. Foram estudados, por tomografia computadorizada, 11 pacientes com proptose ocular causada por tumores malignos extra-orbitários, sem qualquer tratamento prévio do tumor. Houve predomínio de neoplasias não-epiteliais (82%, tendo sido três rabdomiossarcomas (27% e três linfomas não-Hodgkin (27%. Outros sarcomas estiveram presentes em dois casos (18%, seguidos por linfoma de Burkitt (9%, carcinoma epidermóide (9% e carcinoma pouco diferenciado (9%. Nove tumores (82% tiveram origem nas cavidades sinonasais, a maioria (cinco casos com origem no seio etmoidal. Proptose ocular foi a única alteração oftálmica em quatro casos (36%, e um paciente teve proptose ocular bilateral como único sinal da doença. Dezessete órbitas foram acometidas pelos 11 tumores, já que seis pacientes tiveram comprometimento orbitário tumoral bilateral. Os tumores se estenderam às órbitas preferencialmente através da parede óssea orbitária (16 órbitas; 94%. Das 17 órbitas comprometidas, a maioria (59% teve todos os compartimentos lesados. Em 16 órbitas o tumor apresentou situação extraconal. À tomografia computadorizada, proptose ocular esteve presente em 15 das 17 órbitas (88%, tendo sido bilateral em quatro casos (oito órbitas. Houve predomínio de proptose ocular grau 2 à tomografia computadorizada (sete pacientes; 47%. Um total de 44 regiões crânio-faciais foi comprometido, além da órbita e do sítio de origem da neoplasia, indicando a grande extensão loco-regional desses tumores no momento do diagnóstico.

  16. Effect of Ocular Movements during Eye Movement Desensitization and Reprocessing (EMDR Therapy: A Near-Infrared Spectroscopy Study.

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    Daniele Rimini

    Full Text Available Eye Movement Desensitization and Reprocessing (EMDR is a psychotherapeutic treatment resolving emotional distress caused by traumatic events. With EMDR, information processing is facilitated by eye movements (EM during the recall of a traumatic memory (RECALL. The aim of this study is to investigate the effects of ocular movements of EMDR on the hemodynamics of the prefrontal cortex (PFC.Two groups were recruited: a trial group (wEM received a complete EMDR treatment, whereas a control group (woEM received a therapy without EM. PFC hemodynamics was monitored by near-infrared spectroscopy during RECALL and during focusing on the worst image of the trauma (pre-RECALL. The parameters of oxy- (oxy-Hb, and deoxy-hemoglobin (deoxy-Hb were acquired and analyzed in time domain, by calculating the slope within pre-RECALL and RECALL periods, and in the frequency domain, by calculating the mean power of oxy-Hb and deoxy-Hb in the very-low frequency (VLF, 20-40 mHz and low frequency (LF, 40-140 mHz bandwidths. We compared pre-RECALL with RECALL periods within subjects, and pre-RECALL and RECALL parameters of wEM with the corresponding of woEM.An effect of group on mean slope of oxy-Hb and deoxy-Hb in pre-RECALL and oxy-Hb in RECALL periods was observed. wEM showed a lower percentage of positive angular coefficients during pre-RECALL with respect to RECALL, on the opposite of woEM. In the frequency domain, wEM had significant difference in oxy-Hb and deoxy-Hb LF of left hemisphere, whereas woEM showed no difference.We observed the effect of EM on PFC oxygenation during EMDR, since wEM subjects showed a mean increase of oxy-Hb during RECALL and a decrease during pre-RECALL, as opposed to woEM. Frequency analysis evidenced a reduction of activity of sympathetic nervous system in wEM group during pre-RECALL. Our outcomes revealed a different hemodynamics induced by eye movements in wEM with respect to woEM group.

  17. Effect of Ocular Movements during Eye Movement Desensitization and Reprocessing (EMDR) Therapy: A Near-Infrared Spectroscopy Study.

    Science.gov (United States)

    Rimini, Daniele; Molinari, Filippo; Liboni, William; Balbo, Marina; Darò, Roberta; Viotti, Erika; Fernandez, Isabel

    2016-01-01

    Eye Movement Desensitization and Reprocessing (EMDR) is a psychotherapeutic treatment resolving emotional distress caused by traumatic events. With EMDR, information processing is facilitated by eye movements (EM) during the recall of a traumatic memory (RECALL). The aim of this study is to investigate the effects of ocular movements of EMDR on the hemodynamics of the prefrontal cortex (PFC). Two groups were recruited: a trial group (wEM) received a complete EMDR treatment, whereas a control group (woEM) received a therapy without EM. PFC hemodynamics was monitored by near-infrared spectroscopy during RECALL and during focusing on the worst image of the trauma (pre-RECALL). The parameters of oxy- (oxy-Hb), and deoxy-hemoglobin (deoxy-Hb) were acquired and analyzed in time domain, by calculating the slope within pre-RECALL and RECALL periods, and in the frequency domain, by calculating the mean power of oxy-Hb and deoxy-Hb in the very-low frequency (VLF, 20-40 mHz) and low frequency (LF, 40-140 mHz) bandwidths. We compared pre-RECALL with RECALL periods within subjects, and pre-RECALL and RECALL parameters of wEM with the corresponding of woEM. An effect of group on mean slope of oxy-Hb and deoxy-Hb in pre-RECALL and oxy-Hb in RECALL periods was observed. wEM showed a lower percentage of positive angular coefficients during pre-RECALL with respect to RECALL, on the opposite of woEM. In the frequency domain, wEM had significant difference in oxy-Hb and deoxy-Hb LF of left hemisphere, whereas woEM showed no difference. We observed the effect of EM on PFC oxygenation during EMDR, since wEM subjects showed a mean increase of oxy-Hb during RECALL and a decrease during pre-RECALL, as opposed to woEM. Frequency analysis evidenced a reduction of activity of sympathetic nervous system in wEM group during pre-RECALL. Our outcomes revealed a different hemodynamics induced by eye movements in wEM with respect to woEM group.

  18. Planejamento pré-operatório em hepatectomias

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    Fábio Colagrossi Paes-Barbosa

    Full Text Available Hepatectomia pode combinar desde a captação pequeno tumor periférico para operações de grande porte como trissegmentectomia ou ressecções central. Os pacientes podem ser saudáveis, com doença hepática localizada ou cirróticos com alto risco operatório. A avaliação pré-operatória do risco de insuficiência hepática pós-operatório é fundamental para determinar o procedimento cirúrgico adequado. A natureza da doença hepática, a sua gravidade e a operação realizada devem ser considerados para correta preparação pré-operatória. A ressecção hepática deve ser avaliada em relação ao parênquima residual, especialmente em cirróticos, pacientes com hipertensão portal e grandes ressecções. O racional para a utilização de volumetria hepática é medida pelo cirurgião. Child-Pugh, MELD e retenção de verde de indocianina são medidas de avaliação da função do fígado que pode ser usado em hepatectomia pré-operatório. Extremo cuidado deve ser tomado em relação à possibilidade de complicações infecciosas com alta morbidade e mortalidade no período pós-operatório. Vários centros estão desenvolvendo a cirurgia de fígado no mundo, com diminuição do número de complicações. O desenvolvimento da técnica cirúrgica, anestesia, doenças infecciosas, oncologia, terapia intensiva, possível ressecção em pacientes considerados inoperáveis no passado, irão proporcionar melhores resultados no futuro.

  19. [Late complications after chemical burns of the ocular surface. Surgical strategies for ocular surface reconstruction].

    Science.gov (United States)

    Bachmann, B; Cursiefen, C

    2011-10-01

    Severe chemical burns of the ocular surface frequently result in long-standing and ongoing disorders of the conjunctiva and the cornea including conjunctival scarring with shortening of the fornix, cicatricial entropion, complications caused by trichiasis and scarring or chronic ulceration of the cornea. Advanced destruction of limbal stem cells leads to limbal stem cell deficiency with conjunctivalization of the cornea. Surgical therapy aims at the correction of malpositioning of the lids, the reconstruction of the conjunctiva and the fornix utilizing applicable tissue grafts and the reestablishment of a stable, avascular and transparent corneal epithelium by e.g. transplantation of epithelial stem cells. Progressive corneal ulcerations unresponsive to medical therapy can be treated by amniotic membrane transplantation, corneal transplantation or by conjunctival covering depending on the extent of damaged tissue. The surgical therapy of patients after severe chemical burns of the ocular surface is generally performed in specialized centers and occasionally requires a multidisciplinary approach.

  20. Consideraciones del trauma ocular infantil Considerations on the ocular trauma in children

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    Alejandro Arias Díaz

    2012-01-01

    Full Text Available Se realizó una descripción de los aspectos clínicos y el manejo terapéutico del trauma ocular en edades pediátricas. Se identifican las particularidades a abordar en estos pacientes con presencia de cataratas traumáticas y/o heridas penetrantes corneales, por las diferencias en el manejo de las mismas en estas edades y en la adultez. Se hace énfasis en el hifema traumático.The clinical aspects and the treatment management of the ocular trauma at pediatric ages were described. Those particularities to be taken into account when approaching these patients who suffer traumatic cataracts and/or penetrating corneal injuries were indentified, on the account of the differences in the management of this disease between children and adults. Emphasis was made on the description of tra