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Sample records for electrophysiology test station

  1. Materials Test Station

    Data.gov (United States)

    Federal Laboratory Consortium — When completed, the Materials Test Station at the Los Alamos Neutron Science Center will meet mission need. MTS will provide the only fast-reactor-like irradiation...

  2. Electrophysiology of Cranial Nerve Testing: Trigeminal and Facial Nerves.

    Science.gov (United States)

    Muzyka, Iryna M; Estephan, Bachir

    2018-01-01

    The clinical examination of the trigeminal and facial nerves provides significant diagnostic value, especially in the localization of lesions in disorders affecting the central and/or peripheral nervous system. The electrodiagnostic evaluation of these nerves and their pathways adds further accuracy and reliability to the diagnostic investigation and the localization process, especially when different testing methods are combined based on the clinical presentation and the electrophysiological findings. The diagnostic uniqueness of the trigeminal and facial nerves is their connectivity and their coparticipation in reflexes commonly used in clinical practice, namely the blink and corneal reflexes. The other reflexes used in the diagnostic process and lesion localization are very nerve specific and add more diagnostic yield to the workup of certain disorders of the nervous system. This article provides a review of commonly used electrodiagnostic studies and techniques in the evaluation and lesion localization of cranial nerves V and VII.

  3. Testing EDM of Total Stations

    Directory of Open Access Journals (Sweden)

    Cirbus Ján

    2001-03-01

    Full Text Available The paper is devoted to testing electrooptical distance measuring devices (EDM built in total stations, than can be used for various tasks in the contemporary geodetic works. A rich market offer and availability of these universal measuring systems with satisfying distance range, excellent accuracy and other parameters, make total stations as dominant terrestrial geodetic instruments.For succesfully applying these instruments, above all for relliable distance measurements, the stability of the modulation frequency is the most important pre-condition. In the article, therefore, there are given some methods to verify the modulation frequency stability. In addition, some ways for determining the EDM distance constant and periodical corrections of the phase measuring unit are introduced for 4 types of EDM : LEICA 1700L, TOPCON GTS6A, TOPCON GTS2, C.ZEISS ELTA50. It were also investigated their possibilities for precise distance survey. Values of the determined constants and periodical corrections are presented in Tab. 2.Based on the investigation results of the 4 EDM types and using the values m obtained for different distances S, equations of the a posteriori standard deviations in form : m = (a+b.S were derived too.

  4. Automation for a base station stability testing

    OpenAIRE

    Punnek, Elvis

    2016-01-01

    This Batchelor’s thesis was commissioned by Oy LM Ericsson Ab Oulu. The aim of it was to help to investigate and create a test automation solution for the stability testing of the LTE base station. The main objective was to create a test automation for a predefined test set. This test automation solution had to be created for specific environments and equipment. This work included creating the automation for the test cases and putting them to daily test automation jobs. The key factor...

  5. Cardiac autonomic modulation by estrogen in female mice undergoing ambulatory monitoring and in vivo electrophysiologic testing.

    Science.gov (United States)

    Saba, Samir; Shusterman, Vladimir; Usiene, Irmute; London, Barry

    2004-04-01

    Estrogen is an important modulator of cardiovascular risk, but its mechanism of action is not fully understood. We investigated the effect of ovariectomy and its timing on the cardiac electrophysiology in mice. Thirty female mice (age 18.8 +/- 3.1 weeks) underwent in vivo electrophysiologic testing before and after autonomic blockade. Fifteen mice were ovariectomized prepuberty (PRE) and ten postpuberty (POST), 2 weeks prior to electrophysiologic testing. Five age-matched sham-operated female mice (Control) served as controls. A subset of 13 mice (5 PRE, 3 POST, and 5 Controls) underwent 24-hour ambulatory monitoring. With ambulatory monitoring, the average (668 +/- 28 vs 769 +/- 52 b/min, P = 0.008) and minimum (485 +/- 47 vs 587 +/- 53 b/min, P = 0.02) heart rates were significantly slower in the ovariectomized mice (PRE and POST groups) compared to the Control group. At baseline electrophysiologic testing, there were no significant differences among the ovariectomized and intact mice in any of the measured parameters. With autonomic blockade, the Control group had a significantly larger change (delta) in the atrioventricular (AV) nodal Wenckebach (AVW) periodicity (deltaAVW = 11.3 +/- 2.9 vs 2.1 +/- 7.3 ms, P = 0.05) and functional refractory period (deltaFRP = 11.3 +/- 2.1 vs 1.25 +/- 6.8 ms, P = 0.02) compared to the ovariectomized mice. These results were not altered by the time of ovariectomy (PRE vs POST groups). Our results suggest that estrogen modulates the autonomic inputs into the murine sinus and AV nodes. These findings, if replicated in humans, might underlie the observed clustering of certain arrhythmias around menstruation and explain the higher incidence of arrhythmias in men and postmenopausal women.

  6. Hand-arm vibration syndrome: clinical characteristics, conventional electrophysiology and quantitative sensory testing.

    Science.gov (United States)

    Rolke, Roman; Rolke, Silke; Vogt, Thomas; Birklein, Frank; Geber, Christian; Treede, Rolf-Detlef; Letzel, Stephan; Voelter-Mahlknecht, Susanne

    2013-08-01

    Workers exposed to vibrating tools may develop hand-arm vibration syndrome (HAVS). We assessed the somatosensory phenotype using quantitative sensory testing (QST) in comparison to electrophysiology to characterize (1) the most sensitive QST parameter for detecting sensory loss, (2) the correlation of QST and electrophysiology, and (3) the frequency of a carpal tunnel syndrome (CTS) in HAVS. QST, cold provocation tests, fine motor skills, and median nerve neurography were used. QST included thermal and mechanical detection and pain thresholds. Thirty-two patients were examined (54 ± 11 years, 91% men) at the more affected hand compared to 16 matched controls. Vibration detection threshold was the most sensitive parameter to detect sensory loss that was more pronounced in the sensitivity range of Pacinian (150 Hz, x12) than Meissner's corpuscles (20 Hz, x3). QST (84% abnormal) was more sensitive to detect neural dysfunction than conventional electrophysiology (37% abnormal). Motor (34%) and sensory neurography (25%) were abnormal in HAVS. CTS frequency was not increased (9.4%). Findings are consistent with a mechanically-induced, distally pronounced motor and sensory neuropathy independent of CTS. HAVS involves a neuropathy predominantly affecting large fibers with a sensory damage related to resonance frequencies of vibrating tools. Copyright © 2013 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  7. Fuel Cell Stations Automate Processes, Catalyst Testing

    Science.gov (United States)

    2010-01-01

    Glenn Research Center looks for ways to improve fuel cells, which are an important source of power for space missions, as well as the equipment used to test fuel cells. With Small Business Innovation Research (SBIR) awards from Glenn, Lynntech Inc., of College Station, Texas, addressed a major limitation of fuel cell testing equipment. Five years later, the company obtained a patent and provided the equipment to the commercial world. Now offered through TesSol Inc., of Battle Ground, Washington, the technology is used for fuel cell work, catalyst testing, sensor testing, gas blending, and other applications. It can be found at universities, national laboratories, and businesses around the world.

  8. A probe station for testing silicon sensors

    CERN Multimedia

    Ulysse, Fichet

    2017-01-01

    A probe station for testing silicon sensors. The probe station is located inside a dark box that can keep away light during the measurement. The set-up is located in the DSF (Department Silicon Facility). The golden plate is the "chuck" where the sensor is usually placed on. With the help of "manipulators", thin needles can be precisely positioned that can contact the sensor surface. Using these needles and the golden chuck, a high voltage can be applied to the sensor to test its behaviour under high voltage. We will use the silicon sensors that we test here for building prototypes of a highly granular sandwich calorimeter, the CMS HGC (Highly granular Calorimeter) upgrade for High-Luminosity LHC.

  9. Weigh Station and Grid Plate Testing

    International Nuclear Information System (INIS)

    PAJUNEN, A.L.

    2000-01-01

    The purpose of this test is to verify that the Shortened Fuel Canister Hook with Certified Scale (i.e. Weigh Station) can be used to weigh an empty canister from the Canister Well and the empty Primary Cleaning Machine (PCM) Strainer Basket from the process table. Drawing H-1-84835, ''Canister Handling Hook for Fuel Retrieval System Process Table,'' provides details of the Shortened Fuel Canister Hook. It is also necessary to verify that the grid plate can be lifted and tilted over a canister in the canister well. This testing shall be performed before N Reactor fuel is processed through the FRS in Phase 3. The Phase 3 Test will repeatedly weigh fuel and scrap canisters and the PCM strainer basket containing N Reactor fuel (Pajunen, et. al, 2000). Advance testing of this weigh station will ensure that accurate fuel weight data can be recorded in the Phase 3 Test. This document satisfies the requirements EN-6-031-00, ''Testing Process'' for a test plan, test specification and test procedure

  10. High temperature and pressure electrochemical test station

    DEFF Research Database (Denmark)

    Chatzichristodoulou, Christodoulos; Allebrod, Frank; Mogensen, Mogens Bjerg

    2013-01-01

    An electrochemical test station capable of operating at pressures up to 100 bars and temperatures up to 400 ◦C has been established. It enables control of the partial pressures and mass flow of O2, N2, H2, CO2, and H2O in a single or dual environment arrangement, measurements with highly corrosive...... media, as well as localized sampling of gas evolved at the electrodes for gas analysis. A number of safety and engineering design challenges have been addressed. Furthermore, we present a series of electrochemical cell holders that have been constructed in order to accommodate different types of cells...... and facilitate different types of electrochemical measurements. Selected examples of materials and electrochemical cells examined in the test station are provided, ranging from the evaluation of the ionic conductivity of liquid electrolytic solutions immobilized in mesoporous ceramic structures...

  11. Prognostic significance of electrophysiological tests for facial nerve outcome in vestibular schwannoma surgery.

    Science.gov (United States)

    van Dinther, J J S; Van Rompaey, V; Somers, T; Zarowski, A; Offeciers, F E

    2011-01-01

    To assess the prognostic significance of pre-operative electrophysiological tests for facial nerve outcome in vestibular schwannoma surgery. Retrospective study design in a tertiary referral neurology unit. We studied a total of 123 patients with unilateral vestibular schwannoma who underwent microsurgical removal of the lesion. Nine patients were excluded because they had clinically abnormal pre-operative facial function. Pre-operative electrophysiological facial nerve function testing (EPhT) was performed. Short-term (1 month) and long-term (1 year) post-operative clinical facial nerve function were assessed. When pre-operative facial nerve function, evaluated by EPhT, was normal, the outcome from clinical follow-up at 1-month post-operatively was excellent in 78% (i.e. HB I-II) of patients, moderate in 11% (i.e. HB III-IV), and bad in 11% (i.e. HB V-VI). After 1 year, 86% had excellent outcomes, 13% had moderate outcomes, and 1% had bad outcomes. Of all patients with normal clinical facial nerve function, 22% had an abnormal EPhT result and 78% had a normal result. No statistically significant differences could be observed in short-term and long-term post-operative facial function between the groups. In this study, electrophysiological tests were not able to predict facial nerve outcome after vestibular schwannoma surgery. Tumour size remains the best pre-operative prognostic indicator of facial nerve function outcome, i.e. a better outcome in smaller lesions.

  12. Severe Accident Test Station Design Document

    Energy Technology Data Exchange (ETDEWEB)

    Snead, Mary A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yan, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Howell, Michael [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Keiser, James R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrani, Kurt A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-09-01

    The purpose of the ORNL severe accident test station (SATS) is to provide a platform for evaluation of advanced fuels under projected beyond design basis accident (BDBA) conditions. The SATS delivers the capability to map the behavior of advanced fuels concepts under accident scenarios across various temperature and pressure profiles, steam and steam-hydrogen gas mixtures, and thermal shock. The overall facility will include parallel capabilities for examination of fuels and irradiated materials (in-cell) and non-irradiated materials (out-of-cell) at BDBA conditions as well as design basis accident (DBA) or loss of coolant accident (LOCA) conditions. Also, a supporting analytical infrastructure to provide the data-needs for the fuel-modeling components of the Fuel Cycle Research and Development (FCRD) program will be put in place in a parallel manner. This design report contains the information for the first, second and third phases of design and construction of the SATS. The first phase consisted of the design and construction of an out-of-cell BDBA module intended for examination of non-irradiated materials. The second phase of this work was to construct the BDBA in-cell module to test irradiated fuels and materials as well as the module for DBA (i.e. LOCA) testing out-of-cell, The third phase was to build the in-cell DBA module. The details of the design constraints and requirements for the in-cell facility have been closely captured during the deployment of the out-of-cell SATS modules to ensure effective future implementation of the in-cell modules.

  13. Severe Accident Test Station Design Document

    International Nuclear Information System (INIS)

    Snead, Mary A.; Yan, Yong; Howell, Michael; Keiser, James R.; Terrani, Kurt A.

    2015-01-01

    The purpose of the ORNL severe accident test station (SATS) is to provide a platform for evaluation of advanced fuels under projected beyond design basis accident (BDBA) conditions. The SATS delivers the capability to map the behavior of advanced fuels concepts under accident scenarios across various temperature and pressure profiles, steam and steam-hydrogen gas mixtures, and thermal shock. The overall facility will include parallel capabilities for examination of fuels and irradiated materials (in-cell) and non-irradiated materials (out-of-cell) at BDBA conditions as well as design basis accident (DBA) or loss of coolant accident (LOCA) conditions. Also, a supporting analytical infrastructure to provide the data-needs for the fuel-modeling components of the Fuel Cycle Research and Development (FCRD) program will be put in place in a parallel manner. This design report contains the information for the first, second and third phases of design and construction of the SATS. The first phase consisted of the design and construction of an out-of-cell BDBA module intended for examination of non-irradiated materials. The second phase of this work was to construct the BDBA in-cell module to test irradiated fuels and materials as well as the module for DBA (i.e. LOCA) testing out-of-cell, The third phase was to build the in-cell DBA module. The details of the design constraints and requirements for the in-cell facility have been closely captured during the deployment of the out-of-cell SATS modules to ensure effective future implementation of the in-cell modules.

  14. Reload Startup Physics Tests for Tianwan Nuclear Power station

    International Nuclear Information System (INIS)

    Yang Xiaoqiang; Li Wenshuang; Li Youyi; Yao Jinguo; Li Zaipeng Jiangsu

    2010-01-01

    This paper briefly describes the test purposes, test items, test schedules and test equipment's for reload startup physics test's on Unit 1 and 2 of Tianwan Nuclear Power station. Then, an overview of the previous thrice tests and evaluations on the tests results are presented. In the end, the paper shows the development and work direction of optimization project for reload startup physics tests on Unit 1 and 2 of Tianwan Nuclear Power station. (Authors)

  15. Severe Accident Test Station Activity Report

    Energy Technology Data Exchange (ETDEWEB)

    Pint, Bruce A [ORNL; Terrani, Kurt A [ORNL

    2015-06-01

    Enhancing safety margins in light water reactor (LWR) severe accidents is currently the focus of a number of international R&D programs. The current UO2/Zr-based alloy fuel system is particularly susceptible since the Zr-based cladding experiences rapid oxidation kinetics in steam at elevated temperatures. Therefore, alternative cladding materials that offer slower oxidation kinetics and a smaller enthalpy of oxidation can significantly reduce the rate of heat and hydrogen generation in the core during a coolant-limited severe accident. In the U.S. program, the high temperature steam oxidation performance of accident tolerant fuel (ATF) cladding solutions has been evaluated in the Severe Accident Test Station (SATS) at Oak Ridge National Laboratory (ORNL) since 2012. This report summarizes the capabilities of the SATS and provides an overview of the oxidation kinetics of several candidate cladding materials. A suggested baseline for evaluating ATF candidates is a two order of magnitude reduction in the steam oxidation resistance above 1000ºC compared to Zr-based alloys. The ATF candidates are categorized based on the protective external oxide or scale that forms during exposure to steam at high temperature: chromia, alumina, and silica. Comparisons are made to literature and SATS data for Zr-based alloys and other less-protective materials.

  16. Permanent pacemaker implantation in octogenarians with unexplained syncope and positive electrophysiologic testing.

    Science.gov (United States)

    Giannopoulos, Georgios; Kossyvakis, Charalampos; Panagopoulou, Vasiliki; Tsiachris, Dimitrios; Doudoumis, Konstantinos; Mavri, Maria; Vrachatis, Dimitrios; Letsas, Konstantinos; Efremidis, Michael; Katsivas, Apostolos; Lekakis, John; Deftereos, Spyridon

    2017-05-01

    Syncope is a common problem in the elderly, and a permanent pacemaker is a therapeutic option when a bradycardic etiology is revealed. However, the benefit of pacing when no association of symptoms to bradycardia has been shown is not clear, especially in the elderly. The aim of this study was to evaluate the effect of pacing on syncope-free mortality in patients aged 80 years or older with unexplained syncope and "positive" invasive electrophysiologic testing (EPT). This was an observational study. A positive EPT for the purposes of this study was defined by at least 1 of the following: a corrected sinus node recovery time of >525 ms, a basic HV interval of >55 ms, detection of infra-Hisian block, or appearance of second-degree atrioventricular block on atrial decremental pacing at a paced cycle length of >400 ms. Among the 2435 screened patients, 228 eligible patients were identified, 145 of whom were implanted with a pacemaker. Kaplan-Meier analysis determined that time to event (syncope or death) was 50.1 months (95% confidence interval 45.4-54.8 months) with a pacemaker vs 37.8 months (95% confidence interval 31.3-44.4 months) without a pacemaker (log-rank test, P = .001). The 4-year time-dependent estimate of the rate of syncope was 12% vs 44% (P pacemaker implantation was independently associated with longer syncope-free survival. Significant differences were also shown in the individual components of the primary outcome measure (syncope and death from any cause). Copyright © 2017 Heart Rhythm Society. Published by Elsevier Inc. All rights reserved.

  17. Contributions of neuroimaging, balance testing, electrophysiology and blood markers to the assessment of sport-related concussion.

    Science.gov (United States)

    Davis, G A; Iverson, G L; Guskiewicz, K M; Ptito, A; Johnston, K M

    2009-05-01

    To review the diagnostic tests and investigations used in the management of sports concussion, in the adult and paediatric populations, to (a) monitor the severity of symptoms and deficits, (b) track recovery and (c) advance knowledge relating to the natural history and neurobiology of the injury. Qualitative literature review of the neuroimaging, balance testing, electrophysiology, blood marker and concussion literature. PubMed and Medline databases were reviewed for investigations used in the management of adult and paediatric concussion, including structural imaging (computerised tomography, magnetic resonance imaging, diffusion tensor imaging), functional imaging (single photon emission computerised tomography, positron emission tomography, functional magnetic resonance imaging), spectroscopy (magnetic resonance spectroscopy, near infrared spectroscopy), balance testing (Balance Error Scoring System, Sensory Organization Test, gait testing, virtual reality), electrophysiological tests (electroencephalography, evoked potentials, event related potentials, magnetoencephalography, heart rate variability), genetics (apolipoprotein E4, channelopathies) and blood markers (S100, neuron-specific enolase, cleaved Tau protein, glutamate). For the adult and paediatric populations, each test has been classified as being: (1) clinically useful, (2) a research tool only or (3) not useful in sports-related concussion. The current status of the diagnostic tests and investigations is analysed, and potential directions for future research are provided. Currently, all tests and investigations, with the exception of clinical balance testing, remain experimental. There is accumulating research, however, that shows promise for the future clinical application of functional magnetic resonance imaging in sport concussion assessment and management.

  18. Steam Oxidation Testing in the Severe Accident Test Station

    Energy Technology Data Exchange (ETDEWEB)

    Pint, Bruce A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-08-01

    After the March 2011 accident at Fukushima Daiichi, Oak Ridge National Laboratory (ORNL) began conducting high temperature steam oxidation testing of candidate materials for accident tolerant fuel (ATF) cladding in August 2011 [1-11]. The ATF concept is to enhance safety margins in light water reactors (LWR) during severe accident scenarios by identifying materials with 100× slower steam oxidation rates compared to current Zr-based alloys. In 2012, the ORNL laboratory equipment was expanded and made available to the entire ATF community as the Severe Accident Test Station (SATS) [4,12]. Compared to the current UO2/Zr-based alloy fuel system, an ATF alternative would significantly reduce the rate of heat and hydrogen generation in the core during a coolant-limited severe accident [13-14]. The steam oxidation behavior of candidate materials is a key metric in the evaluation of ATF concepts and also an important input into models [15-17]. However, initial modeling work of FeCrAl cladding has used incomplete information on the physical properties of FeCrAl. Also, the steam oxidation data being collected at 1200°-1700°C is unique as no prior work has considered steam oxidation of alloys at such high temperatures. Also, because many accident scenarios include steadily increasing temperatures, the required data are not traditional isothermal exposures but exposures with varying “ramp” rates. In some cases, the steam oxidation behavior has been surprising and difficult to interpret. Thus, more fundamental information continues to be collected. In addition, more work continues to focus on commercially-manufactured tube material. This report summarizes recent work to characterize the behavior of candidate alloys exposed to high temperature steam, evaluate steam oxidation behavior in various ramp scenarios and continue to collect integral data on FeCrAl compared to conventional Zr-based cladding.

  19. Probe station for testing of ALICE silicon drift detectors

    CERN Document Server

    Humanic, T J; Piemonte, C; Rashevsky, A; Sugarbaker, E R; Vacchi, A

    2003-01-01

    Large area, 7.25 cm multiplied by 8.76 cm silicon drift detectors have been developed and are in production for the ALICE experiment at LHC. An active area of the detector of more than 50 cm**2 imposes high demands on the quality of processing and raw material. Automated testing procedures have been developed to test detectors before mounting them on the ladders. Probe stations for ALICE SDD testing were designed and built at INFN, Trieste and Ohio State University (OSU). Testing procedures, detector selection criteria and some details of the OSU probe station design are discussed.

  20. Evaluation of data from HEPA filter quality assurance testing stations

    International Nuclear Information System (INIS)

    Collins, J.T.; Bellamy, R.R.; Allen, J.R.

    1979-01-01

    In Revision 1 to Regulatory Guide 1.52, issued in July 1976, the NRC recommended that high efficiency particulate air (HEPA) filters for use in engineered safety features (ESF) atmosphere cleanup systems be visually inspected and dioctylphtalate (DOP) tested at either of two Department of Energy (DOE) operated QA Filter Testing Stations prior to their installation and use in commercial nuclear power plants. This practice was initiated because filter vendors were unable to consistently provide a HEPA filter that would meet the stringent requirements established by DOE and NRC and its predecessor the AEC. In 1977, the NRC staff undertook a program to revise Regulatory Guide 1.52 to reflect recently issued industry standards (e.g., ANSI N509 and N510) and current industry practices. Revision 2 to Regulatory Guide 1.52 was formally issued in March 1978. In conducting this review, the recommendation that HEPA filters, intended for use in ESF systems in commercial nuclear power plants, be routinely tested at the DOE-QA Filter Testing Stations was revaluated. As part of this evluation a detailed analysis of the filter test results recorded by the two QA Testing Stations during the period 1971 to 1977 was conducted. This paper summarizes the results of the analysis and explains the rationale for deleting the requirement that all HEPA filters intended for use in ESF systems be tested at the AQ Testing Station

  1. Lewis Research Center space station electric power system test facilities

    Science.gov (United States)

    Birchenough, Arthur G.; Martin, Donald F.

    1988-01-01

    NASA Lewis Research Center facilities were developed to support testing of the Space Station Electric Power System. The capabilities and plans for these facilities are described. The three facilities which are required in the Phase C/D testing, the Power Systems Facility, the Space Power Facility, and the EPS Simulation Lab, are described in detail. The responsibilities of NASA Lewis and outside groups in conducting tests are also discussed.

  2. Test Station for Measuring Aluminum Tube Geometrical Parameters

    CERN Document Server

    Oansea, D; Gongadze, A L; Gostkin, M I; Dedovich, D V; Evtoukhovitch, P G; Comanescu, B; Kotov, S A; Necsoiu, T; Potrap, I N; Rogalev, E V; Tskhadadze, E G; Chelkov, G A

    2001-01-01

    A test station for quality control of aluminum tube outer diameter and wall thickness is presented. The tested tubes are used for drift detector assembly of ATLAS (LHC, CERN) muon system. The outer diameter and wall thickness of aluminium tubes are measured by means of noncontact optical and ultrasonic methods respectively with the accuracy of 3 {\\mu}m. The testing process is automatic and interacts with the production data base.

  3. In vivo electrophysiological measurement of the rat ulnar nerve with axonal excitability testing

    DEFF Research Database (Denmark)

    Wild, Brandon M.; Morris, Renée; Moldovan, Mihai

    2018-01-01

    Electrophysiology enables the objective assessment of peripheral nerve function in vivo. Traditional nerve conduction measures such as amplitude and latency detect chronic axon loss and demyelination, respectively. Axonal excitability techniques "by threshold tracking" expand upon these measures...... by providing information regarding the activity of ion channels, pumps and exchangers that relate to acute function and may precede degenerative events. As such, the use of axonal excitability in animal models of neurological disorders may provide a useful in vivo measure to assess novel therapeutic...... interventions. Here we describe an experimental setup for multiple measures of motor axonal excitability techniques in the rat ulnar nerve. The animals are anesthetized with isoflurane and carefully monitored to ensure constant and adequate depth of anesthesia. Body temperature, respiration rate, heart rate...

  4. Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography.

    Science.gov (United States)

    Zheng, Hua-Guang; Zhang, Rong; Li, Xin; Li, Fang-Fei; Wang, Ya-Chen; Wang, Xue-Mei; Lu, Ling-Long; Feng, Tao

    2015-07-05

    The relationship between monosymptomatic resting tremor (mRT) and Parkinson's disease (PD) remains controversial. In this study, we aimed to assess the function of presynaptic dopaminergic neurons in patients with mRT by dopamine transporter positron emission tomography (DAT-PET) and to evaluate the utility of clinical features or electrophysiological studies in differential diagnosis. Thirty-three consecutive patients with mRT were enrolled prospectively. The Unified Parkinson's Disease Rating Scale and electromyography were tested before DAT-PET. Striatal asymmetry index (SAI) was calculated, and a normal DAT-PET was defined as a SAI of hygiene score, walking in motor experiences of daily living (Part II) and motor examination (Part III) were significant different between two groups (P postural tremor tend to be higher in the SWEDDs group (P = 0.08 and P = 0.05, respectively). mRT is heterogeneous in presynaptic nigrostriatal dopaminergic degeneration, which can be determined by DAT-PET brain imaging. Clinical and electrophysiological features may provide clues to distinguish PD from SWEDDs.

  5. Environmental qualification test of electrical penetration for nuclear power stations

    International Nuclear Information System (INIS)

    Kooziro, Tetsuya; Nakagawa, Akitoshi; Toyoda, Shigeru; Uno, Shunpei

    1979-01-01

    Environmental qualification test was conducted according to IEEE Std. 323-1974 in order to evaluate the safety and reliability of electrical penetration of PWR type nuclear power station. Electrical penetration is the assemblies of electric cables attached to the containment vessel and penetrate through the vessel. Since it is a part of the vessel, it is deemed to be one of the primary safety equipments that are important for the safety and reliability of nuclear power stations. Environmental tests were conducted continuously as to heat cycle, vibration and LOCA with the full size specimens of bushing type, pigtail type and triaxial cable type and at the same time thermal life and irradiation tests were conducted on the insulation materials used, in order to obtain the comprehensive evaluation of their electrical and mechanical characteristics. As the result, they all satisfied the requirements for the circuits for actual use during and after various environmental qualification tests according to IEEE Std. 323. (author)

  6. System Studies for the ADTF: Target and Materials Test Station

    International Nuclear Information System (INIS)

    Cappiello, M.; Pitcher, E.; Pasamehmetoglu, K.

    2002-01-01

    To meet the objectives of the Advanced Accelerator Applications (AAA) program, the Accelerator-Driven Test Facility (ADTF) provides a world-class accelerator-driven test facility to: - Provide the capability to assess technology options for the transmutation of spent nuclear fuel and waste through a proof-of-performance. - Provide a user facility that allows testing of advanced nuclear technologies and applications, material science and research, experimental physics, and conventional nuclear engineering science applications. - Provide the capability, through upgrades or additions to the ADTF accelerator, to produce tritium for defense purposes, if required. - Provide the capability, through upgrades or additions, to produce radioisotopes for medical and commercial purposes. These missions are diverse and demand a facility with significant flexibility. In order to meet them, it is envisioned that we construct two target stations: the Target and Materials Test (TMT) station and the Subcritical Multiplier (SCM) test station. The two test stations share common hot-cell facilities for post-irradiation examination. It is expected the TMT will come online first, closely followed by the SCM. The TMT will provide the capability to: - Irradiate small samples of proposed ATW (accelerator-driven transmutation of waste) fuels and materials at prototypic flux, temperature, and coolant conditions (requires intense source of neutrons). - Perform transient testing. - Test liquid (lead-bismuth) and solid spallation targets with water, sodium, or helium coolant. - Test generation-IV fuels for advance nuclear systems (requires high-intensity thermal flux). - Irradiate fission product transmutation targets. - Test advanced fuel and coolant combinations, including helium, water, sodium, and lead-bismuth. - Produce isotopes for commercial and medical applications. - Perform neutron physics experiments. The SCM will provide the capability to: - Irradiate large samples of proposed ATW

  7. Electrophysiological correlates of the autobiographical Implicit Association Test (aIAT: response conflict and conflict resolution.

    Directory of Open Access Journals (Sweden)

    Maddalena Marini

    2016-08-01

    Full Text Available The autobiographical IAT (aIAT is an implicit behavioral instrument that can detect autobiographical memories encoded in an individual’s mind by measuring how quickly this person can categorize and associate sentences related to a specific event with the logical dimensions true and false. Faster categorization when an event (e.g., I went to Paris is associated with the dimension true than false indicates that that specific event is encoded as true in the individual’s mind. The aim of this study is to investigate the electrophysiological correlates of the aIAT, used as a memory-detection technique (i.e., to identify which of two events is true. To this end, we recorded ERPs while participants performed an aIAT assessing which of two playing cards they had previously selected. We found an increased N200 and a decreased LPC (or P300 at the fronto-central sites when participants associated the selected playing card with the dimension false than true. Notably, both components have been previously and consistently reported in studies investigating deception. These results suggest that associating a true autobiographical event with the concept of false may involve the same cognitive processes associated with deception.

  8. Visual electrophysiology in children

    Directory of Open Access Journals (Sweden)

    Jelka Brecelj

    2005-10-01

    Full Text Available Background: Electrophysiological assessment of vision in children helps to recognise abnormal development of the visual system when it is still susceptible to medication and eventual correction. Visual electrophysiology provides information about the function of the retina (retinal pigment epithelium, cone and rod receptors, bipolar, amacrine, and ganglion cells, optic nerve, chiasmal and postchiasmal visual pathway, and visual cortex.Methods: Electroretinograms (ERG and visual evoked potentials (VEP are recorded non-invasively; in infants are recorded simultaneously ERG with skin electrodes, while in older children separately ERG with HK loop electrode in accordance with ISCEV (International Society for Clinical Electrophysiology of Vision recommendations.Results: Clinical and electrophysiological changes in children with nystagmus, Leber’s congenital amaurosis, achromatopsia, congenital stationary night blindness, progressive retinal dystrophies, optic nerve hypoplasia, albinism, achiasmia, optic neuritis and visual pathway tumours are presented.Conclusions: Electrophysiological tests can help to indicate the nature and the location of dysfunction in unclear ophthalmological and/or neurological cases.

  9. Modal Testing of Seven Shuttle Cargo Elements for Space Station

    Science.gov (United States)

    Kappus, Kathy O.; Driskill, Timothy C.; Parks, Russel A.; Patterson, Alan (Technical Monitor)

    2001-01-01

    From December 1996 to May 2001, the Modal and Control Dynamics Team at NASA's Marshall Space Flight Center (MSFC) conducted modal tests on seven large elements of the International Space Station. Each of these elements has been or will be launched as a Space Shuttle payload for transport to the International Space Station (ISS). Like other Shuttle payloads, modal testing of these elements was required for verification of the finite element models used in coupled loads analyses for launch and landing. The seven modal tests included three modules - Node, Laboratory, and Airlock, and four truss segments - P6, P3/P4, S1/P1, and P5. Each element was installed and tested in the Shuttle Payload Modal Test Bed at MSFC. This unique facility can accommodate any Shuttle cargo element for modal test qualification. Flexure assemblies were utilized at each Shuttle-to-payload interface to simulate a constrained boundary in the load carrying degrees of freedom. For each element, multiple-input, multiple-output burst random modal testing was the primary approach with controlled input sine sweeps for linearity assessments. The accelerometer channel counts ranged from 252 channels to 1251 channels. An overview of these tests, as well as some lessons learned, will be provided in this paper.

  10. Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography

    Institute of Scientific and Technical Information of China (English)

    Hua-Guang Zheng; Rong Zhang; Xin Li; Fang-Fei Li; Ya-Chen Wang; Xue-Mei Wang; Ling-Long Lu

    2015-01-01

    Background:The relationship between monosymptomatic resting tremor (mRT) and Parkinson's disease (PD) remains controversial.In this study,we aimed to assess the function ofpresynaptic dopaminergic neurons in patients with mRT by dopamine transporter positron emission tomography (DAT-PET) and to evaluate the utility of clinical features or electrophysiological studies in differential diagnosis.Methods:Thirty-three consecutive patients with mRT were enrolled prospectively.The Unified Parkinson's Disease Rating Scale and electromyography were tested before DAT-PET.Striatal asymmetry index (SAI) was calculated,and a normal DAT-PET was defined as a SAI of <15%.Scans without evidence of dopaminergic deficits (SWEDDs) were diagnosed in patients with a subsequent normal DAT-PET and structural magnetic resonance imaging.Results:Twenty-eight mRT patients with a significant reduction in uptake of DAT binding in the striatum were diagnosed with PD,while the remained 5 with a normal DAT-PET scan were SWEDDs.As for UPRDS,the dressing and hygiene score,walking in motor experiences of daily living (Part Ⅱ) and motor examination (Part Ⅲ) were significant different between two groups (P < 0.05 andP< 0.01,respectively).Bilateral tremor was more frequent in the SWEDDs group (P < 0.05).The frequency of resting tremor and the amplitude of postural tremor tend to be higher in the SWEDDs group (P =0.08 and P =0.05,respectively).Conclusions:mRT is heterogeneous in presynaptic nigrostriatal dopaminergic degeneration,which can be determined by DAT-PET brain imaging.Clinical and electrophysiological features may provide clues to distinguish PD from SWEDDs.

  11. A computer-assisted test for the electrophysiological and psychophysical measurement of dynamic visual function based on motion contrast.

    Science.gov (United States)

    Wist, E R; Ehrenstein, W H; Schrauf, M; Schraus, M

    1998-03-13

    A new test is described that allows for electrophysiological and psychophysical measurement of visual function based on motion contrast. In a computer-generated random-dot display, completely camouflaged Landolt rings become visible only when dots within the target area are moved briefly while those of the background remain stationary. Thus, detection of contours and the location of the gap in the ring rely on motion contrast (form-from-motion) instead of luminance contrast. A standard version of this test has been used to assess visual performance in relation to age, in screening professional groups (truck drivers) and in clinical groups (glaucoma patients). Aside from this standard version, the computer program easily allows for various modifications. These include the option of a synchronizing trigger signal to allow for recording of time-locked motion-onset visual-evoked responses, the reversal of target and background motion, and the displacement of random-dot targets across stationary backgrounds. In all instances, task difficulty is manipulated by changing the percentage of moving dots within the target (or background). The present test offers a short, convenient method to probe dynamic visual functions relying on surprathreshold motion-contrast stimuli and complements other routine tests of form, contrast, depth, and color vision.

  12. Space Station CMIF extended duration metabolic control test

    Science.gov (United States)

    Schunk, Richard G.; Bagdigian, Robert M.; Carrasquillo, Robyn L.; Ogle, Kathryn Y.; Wieland, Paul O.

    1989-01-01

    The Space Station Extended Duration Metabolic Control Test (EMCT) was conducted at the MSFC Core Module Integration Facility. The primary objective of the EMCT was to gather performance data from a partially-closed regenerative Environmental Control and Life Support (ECLS) system functioning under steady-state conditions. Included is a description of the EMCT configuration, a summary of events, a discussion of anomalies that occurred during the test, and detailed results and analysis from individual measurements of water and gas samples taken during the test. A comparison of the physical, chemical, and microbiological methods used in the post test laboratory analyses of the water samples is included. The preprototype ECLS hardware used in the test, providing an overall process description and theory of operation for each hardware item. Analytical results pertaining to a system level mass balance and selected system power estimates are also included.

  13. Heterogeneity of Monosymptomatic Resting Tremor in a Prospective Study: Clinical Features, Electrophysiological Test, and Dopamine Transporter Positron Emission Tomography

    Directory of Open Access Journals (Sweden)

    Hua-Guang Zheng

    2015-01-01

    Conclusions: mRT is heterogeneous in presynaptic nigrostriatal dopaminergic degeneration, which can be determined by DAT-PET brain imaging. Clinical and electrophysiological features may provide clues to distinguish PD from SWEDDs.

  14. Engineering test station for TFTR blanket module experiments

    International Nuclear Information System (INIS)

    Jassby, D.L.; Leinoff, S.

    1979-12-01

    A conceptual design has been carried out for an Engineering Test Station (ETS) which will provide structural support and utilities/instrumentation services for blanket modules positioned adjacent to the vacuum vessel of the TFTR (Tokamak Fusion Test Reactor). The ETS is supported independently from the Test Cell floor. The ETS module support platform is constructed of fiberglass to eliminate electromagnetic interaction with the pulsed tokamak fields. The ETS can hold blanket modules with dimensions up to 78 cm in width, 85 cm in height, and 105 cm in depth, and with a weight up to 4000 kg. Interfaces for all utility and instrumentation requirements are made via a shield plug in the TFTR igloo shielding. The modules are readily installed or removed by means of TFTR remote handling equipment

  15. metrological performance improvement of a superconducting cable test station

    CERN Document Server

    Montenero, Giuseppe; Ballarino, Amalia

    The work presented in this PhD thesis concerns the metrological performance improvement of a superconducting cable test station based on superconducting transformers. The main cable’s parameter to be assessed –as a function of temperature and magnetic field– is the critical current, i.e. beyond this limit the phase transition to the normal state occurs. Ramping the current at levels in the order of the tens of kA can be achieved with superconducting transformers at moderate capital and operational cost. But, issues such as (i) accurate/precise measurements and (ii) monitoring of the secondary current during the device operation have to be addressed. In this regard, the goals of the thesis are the design, prototyping, and validation of a new cryogenic current transducer and effective monitoring system for test stations transformer-based. Among the available transducers for current sensing at room temperature, the DC current transformer (DCCT) provides measurement accuracy in the order of the hundreds of ...

  16. Vdrive Evaluation of Remote Steering and Testing in Lasso Electrophysiology Procedures Study: The VERSATILE Study in Atrial Fibrillation Ablation.

    Science.gov (United States)

    Nölker, Georg; Schwagten, Bruno; Deville, J Brian; Burkhardt, J David; Horton, Rodney P; Sha, Qun; Tomassoni, Gery

    2016-03-01

    Circular mapping catheters (CMC) are an essential tool in most atrial fibrillation ablation procedures. The Vdrive™ with V-Loop™ system enables a physician to remotely manipulate a CMC during electrophysiology studies. Our aim was to compare the clinical performance of the system to conventional CMC navigation according to efficiency and safety endpoints. A total of 120 patients scheduled to undergo a CMC study followed by pulmonary vein isolation (PVI) were included. Treatment allocation was randomized 2:1, remote navigation:manual navigation. The primary effectiveness endpoint was assessed based on both successful navigation to the targeted pulmonary vein (PV) and successful recording of PV electrograms. All PVs were treated independently within and between patients. The primary safety endpoint was assessed based on the occurrence of major adverse events (MAEs) through seven days after the study procedure. Primary effectiveness endpoints were achieved in 295/302 PVs in the Vdrive arm (97.7%) and 167/167 PVs in the manual arm (100%). Effectiveness analysis indicates Vdrive non-inferiority (pnon-inferiority = 0.0405; δ = -0.05) per the Cochran-Mantel-Haenszel test adjusted for PV correlation. Five MAEs related to the ablation procedure occurred (three in the Vdrive arm-3.9%; two in the manual arm-2.33%). No device-related MAEs were observed; safety analysis indicates Vdrive non-inferiority (pnon-inferiority = 0.0441; δ = 0.07) per the normal Z test. Remote navigation of a CMC is equivalent to manual in PVI in terms of safety and effectiveness. This allows for single-operator procedures in conjunction with a magnetically guided ablation catheter. © 2016 Wiley Periodicals, Inc.

  17. Phase III Simplified Integrated Test (SIT) results - Space Station ECLSS testing

    Science.gov (United States)

    Roberts, Barry C.; Carrasquillo, Robyn L.; Dubiel, Melissa Y.; Ogle, Kathryn Y.; Perry, Jay L.; Whitley, Ken M.

    1990-01-01

    During 1989, phase III testing of Space Station Freedom Environmental Control and Life Support Systems (ECLSS) began at Marshall Space Flight Center (MSFC) with the Simplified Integrated Test. This test, conducted at the MSFC Core Module Integration Facility (CMIF), was the first time the four baseline air revitalization subsystems were integrated together. This paper details the results and lessons learned from the phase III SIT. Future plans for testing at the MSFC CMIF are also discussed.

  18. Development of Test Protocols for International Space Station Particulate Filters

    Science.gov (United States)

    Vijayakumar, R.; Green, Robert D.; Agui, Juan H.

    2015-01-01

    Air quality control on the International Space Station (ISS) is a vital requirement for maintaining a clean environment for the crew and the hardware. This becomes a serious challenge in pressurized space compartments since no outside air ventilation is possible, and a larger particulate load is imposed on the filtration system due to lack of gravitational settling. The ISS Environmental Control and Life Support System (ECLSS) uses a filtration system that has been in use for over 14 years and has proven to meet this challenge. The heart of this system is a traditional High-Efficiency Particulate Air (HEPA) filter configured to interface with the rest of the life support elements and provide effective cabin filtration. The filter element for this system has a non-standard cross-section with a length-to-width ratio (LW) of 6.6. A filter test setup was designed and built to meet industry testing standards. A CFD analysis was performed to initially determine the optimal duct geometry and flow configuration. Both a screen and flow straighter were added to the test duct design to improve flow uniformity and face velocity profiles were subsequently measured to confirm. Flow quality and aerosol mixing assessments show that the duct flow is satisfactory for the intended leak testing. Preliminary leak testing was performed on two different ISS filters, one with known perforations and one with limited use, and results confirmed that the testing methods and photometer instrument are sensitive enough to detect and locate compromised sections of an ISS BFE.Given the engineering constraints in designing spacecraft life support systems, it is anticipated that non-industry standard filters will be required in future designs. This work is focused on developing test protocols for testing the ISS BFE filters, but the methodology is general enough to be extended to other present and future spacecraft filters. These techniques for characterizing the test duct and perform leak testing

  19. Axonal electrovisiogram as an electrophysiological test to evaluate optic nerve and inner retina electrical potentials: findings in normal subjects

    Directory of Open Access Journals (Sweden)

    Wener Passarinho Cella

    2011-02-01

    Full Text Available PURPOSES: To standardize and validate the technique of axonal electrovisiogram (AxEvg, defining its normative values and parameters and characterizing its findings in normal individuals. METHODS: We enrolled 140 normal individuals (280 eyes divided into seven groups according to age, each one with 10 males and 10 females. The technique was based on monocular visual stimulation by a 0 dB intensity bright flash on Ganzfeld bowl at a presentation rate of 1.4 Hz. Golden cup electrodes were used and electrical waves were acquired after artifact rejection. For each amplitude and implicit time peak we calculated the mean, median, pattern deviation, minimum and maximum values and 95% confidence interval. RESULTS: Monocular visual stimulation with bright flash under mesopic conditions was the standard technical procedure established. The normal AxEvg waveform consists of an initial positive wave (named P1, with mean amplitude of 2.0 mV and mean implicit time peak of 23.1 ms followed by a negative wave (named N1, with mean amplitude of -3.9 mV and mean implicit time peak of 41.4 ms. No significant differences were observed between males and females or between right and left eyes, but there was an increased P1 and N1 implicit time peaks according to age. Implicit time characteristics suggest that P1 wave represents an optic nerve electrical potential and N1 wave represents an inner retinal layers potential. CONCLUSIONS: AxEvg can be considered a pre-chiasmatic visual evoked potential capable to reliably record the electrical activity of optic nerve and inner retina. The findings suggest that AxEvg may be useful as an electrophysiological test in the diagnosis of neuroretinal diseases.

  20. Investigation of a Station Blackout Scenario with the ATLAS Test

    International Nuclear Information System (INIS)

    Kim, Yeon Sik; Yu, Xin Guo; Kang, Kyoung Ho; Park, Hyun Sik; Cho, Seok; Min, Kyeong Ho; Choi, Nam Hyeon; Kim, Bok Deuk; Park, Jong Gook; Choi, Ki Yong

    2012-01-01

    KAERI (Korea Atomic Energy Research Institute) has been operating an integral effect test facility, ATLAS (Advanced Thermal-Hydraulic Test Loop for Accident Simulation), for accident simulations pertaining to the OPR1000 (Optimized Power Reactor, 1000MWe) and the APR1400 (Advanced Power Reactor, 1400MWe) which are in operation and under construction in Korea, respectively. After the Fukushima accidents due to the combination of an earthquake followed by a tsunami in east Japan on March 11, 2011, the concept of boundary between the design basis and beyond-design basis accidents became obscure. One scenario is the station blackout (SBO), which is defined as 'the loss of all alternating current (AC) power in a nuclear power plant' by the USNRC 10CFR50 Section 50.63, which has adopted a new safety regulation for the SBO in June of 1988. In any case the SBO that occurred in Fukushima seemed to go beyond the definition of the current SBO scenario. In the mean time, numerous researches has been conducted on the safety concern of the SBO for existing and advanced nuclear power plants worldwide. From the internal review of an SBO scenario, it was concluded that the understanding of the thermo-hydraulic phenomena occurred within the reactor coolant system is a prerequisite although seemed to be quite a simple sequence of events. This was the motivation of an SBO test using the ATLAS facility. For the understanding of the physical phenomena within the primary system, an SBO was assumed with simple intial and boundary conditions, e.g. start of an SBO at time zero, no diesel and AC powers, no auxiliary feedwater pumps (motor-driven and turbine driven) etc. In this paper, overview of the SBO test results was described including a result of analytical calculations simulating the SBO test using the MARS code

  1. The Space Station Photovoltaic Panels Plasma Interaction Test Program: Test plan and results

    Science.gov (United States)

    Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

    1989-01-01

    The Plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

  2. The Space Station photovoltaic panels plasma interaction test program - Test plan and results

    Science.gov (United States)

    Nahra, Henry K.; Felder, Marian C.; Sater, Bernard L.; Staskus, John V.

    1990-01-01

    The plasma Interaction Test performed on two space station solar array panels is addressed. This includes a discussion of the test requirements, test plan, experimental set-up, and test results. It was found that parasitic current collection was insignificant (0.3 percent of the solar array delivered power). The measured arcing threshold ranged from -210 to -457 V with respect to the plasma potential. Furthermore, the dynamic response of the panels showed the panel time constant to range between 1 and 5 microsec, and the panel capacitance to be between .01 and .02 microF.

  3. Test of thermal shields for early warning station detectors

    DEFF Research Database (Denmark)

    Petersen, Jesper

    1997-01-01

    The properties of thermal shields around NaI crystal scintillators for early warning stations have been checked in order to assure that external temperature variations cannot influence the stability of the measurements....

  4. Fuel Retrieval Sub-Project (FRS) Stuck Fuel Station Performance Test Data Report

    International Nuclear Information System (INIS)

    THIELGES, J.R.

    2000-01-01

    This document provides the test data report for Stuck Fuel Station Performance Testing in support of the Fuel Retrieval Sub-Project. The stuck fuel station was designed to provide a means of cutting open a canister barrel to release fuel elements, etc

  5. Principal facts for about 16,000 gravity stations in the Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Harris, R.N.; Ponce, D.A.; Oliver, H.W.; Healey, D.L.

    1989-01-01

    The Nevada Test Site (NTS) and vicinity includes portions of the Goldfield, Caliente, Death Valley, and Las Vegas. This report documents and consolidates previously published and recently compiled gravity data to establish a gravity data base of about 16,000 stations for the NTS and vicinity. While compiling data sets, redundant stations and stations having doubtful locations or gravity values were excluded. Details of compiling the gravity data sets are discussed in later sections. Where feasible, an accuracy code has been assigned to each station so that the accuracy or reliability of each station can be evaluated. This data base was used in preparing complete Bouguer and isostatic gravity maps of the NTS and vicinity. Since publication of the complete Bouguer gravity map, additional data were incorporated into the isostatic gravity map. Gravity data were compiled from five sources: 14,183 stations from the US Geological Survey (USGS), 326 stations from Exploration Data Consultants (EDCON) of Denver, Colorado, 906 stations from the Los Alamos National Laboratory (LANL), 212 stations from the University of Texas at Dallas (UTD), and 48 stations from the Defense Mapping Agency (DMA). This investigation is an effort to study several areas for potential storage of high-level radioactive waste. Gravity stations established under YMP are shown. The objective of this gravity survey was to explore for the presence of plutons. 33 refs., 24 figs., 9 tabs

  6. Principal facts for about 16,000 gravity stations in the Nevada Test Site and vicinity

    International Nuclear Information System (INIS)

    Harris, R.N.; Ponce, D.A.; Oliver, H.W.; Healey, D.L.

    1989-01-01

    The Nevada Test Site (NTS) and vicinity includes portions of the Goldfield, Caliente, Death Valley, and Las Vegas. This report documents and consolidates previously published and recently compiled gravity data to establish a gravity data base of about 16,000 stations for the NTS and vicinity. While compiling data sets, redundant stations and stations having doubtful locations or gravity values were excluded. Details of compiling the gravity data sets are discussed in later sections. Where feasible, an accuracy code has been assigned to each station so that the accuracy or reliability of each station can be evaluated. This data base was used in preparing complete Bouguer and isostatic gravity maps of the NTS and vicinity. Since publication of the complete Bouguer gravity map, additional data were incorporated into the isostatic gravity map. Gravity data were compiled from five sources: 14,183 stations from the US Geological Survey (USGS), 326 stations from Exploration Data Consultants (EDCON) of Denver, Colorado, 906 stations from the Los Alamos National Laboratory (LANL), 212 stations from the University of Texas at Dallas (UTD), and 48 stations from the Defense Mapping Agency (DMA). This investigation is an effort to study several areas for potential storage of high-level radioactive waste. Gravity stations established under YMP are shown. The objective of this gravity survey was to explore for the presence of plutons. This volume contains only compiled data

  7. Design of a test station for the CMS HCAL waveshifter/waveguide fiber system

    CERN Document Server

    Baumbaugh, B; Kozminski, J; Lu, Q; Ruchti, R C; Wayne, M; Budd, H S; De Barbaro, P; Skup, E

    1998-01-01

    A test station has been designed and is under construction to test the quality of assembled waveguide to waveshifter fiber to be used in the scintillating tile calorimeter for the Compact Moun Solenoid (CMS) Hadron Calorimeter $9 (HCAL). The test station consists of a light tight enclosure 6.8 meters long with the ability to move a light source over almost 6 meters of fiber. Data acquisition hardware and software are under development to analyze the quality $9 of the fiber as well as motor control hardware and software to operate the moveable light source. The design and performance expectations of the test station will be presented. (6 refs).

  8. Summary of ROSA-4 LSTF first phase test program and station blackout (TMLB) test results

    International Nuclear Information System (INIS)

    Tasaka, K.; Kukita, Y.; Anoda, Y.

    1990-01-01

    This paper summarizes major test results obtained at the ROSA-4 Large Scale Test Facility (LSTF) during the first phase of the test program. The results from a station blackout (TMLB) test conducted at the end of the first-phase program are described in some detail. The LSTF is an integral test facility being operated by the Japan Atomic Energy Research Institute for simulation of pressurized water reactor (PWR) thermal-hydraulic responses during small-break loss-of-coolant accidents (SBLOCAs) and operational/abnormal transients. It is a 1/48 volumetrically scaled, full-height, full-pressure simulator of a Westinghouse-type 4-loop PWR. The facility includes two symmetric primary loops each one containing an active inverted-U tube steam generator and an active reactor coolant pump. The loop horizontal legs are sized to conserve the scaled (1/24) volumes as well as the length to the square root of the diameter ratio in order to simulate the two-phase flow regime transitions. The primary objective of the LSTF first-phase program was to define the fundamental PWR thermal-hydraulic responses during SBLOCAs and transients. Most of the tests were conducted with simulated component/operator failures, including unavailability of the high pressure injection system and auxiliary feedwater system, as well as operator failure to take corrective actions. The forty-two first phase tests included twenty-nine SBLOCA tests conducted mainly for cold leg breaks, three abnormal transient tests and ten natural circulation tests. Attempts were made in several of the SBLOCA tests to simulate the plant recovery procedures as well as candidate accident management measures for prevention of high-pressure core melt situation. The natural circulation tests simulated the single-phase and two-phase natural circulation as well as reflux condensation behavior in the primary loops in steady or quasi-steady states

  9. Diagnostic testing and repair of Hollingsworth Generating Station`s Unit One

    Energy Technology Data Exchange (ETDEWEB)

    Atkins, R.; Epple, W.; Stevenson, D. [Great Lakes Power Ltd., Sault Ste. Marie, ON (Canada); Brotherton, L.; Crahan, M.; Ghate, A.

    1995-12-31

    A case history of the diagnosis and corrections implemented to resolve vibration problems in a 22,222 kVA hydroelectric generator was presented. The problem prevented the utility from operating the unit throughout the range of its nameplate rating and caused periodic failures of the generator`s guide and thrust bearing. Tests identified that the rim assembly was fastened onto the spider in a manner that resulted in tilting of the rim with respect to the axis of rotation, consequently, there was an unbalanced generator static air gap. A unique repair was implemented to fully restore the rim assembly to its proper position. Problems associated with carrying out such major in-situ repairs in a remote environment and within a scheduled maintenance outage were discussed. Economic benefits and costs associated with the repair were also discussed.

  10. Hydrogeological investigations in two boreholes in the Stripa test station

    International Nuclear Information System (INIS)

    Hansson, K.; Almen, K.-E.; Ekman, L.

    1978-01-01

    The investigations included the following: water injection tests in a horizontal core-borehole, Dbh 2; hydrostatic pressure tests in Dbh2; determination of permeability in a vertical core-borehole, Dbh VI. The results of the water injection tests gave very little information due to the fact, that an air cushion was trapped in the borehole. The hydrostatic pressure tests in Dbh 2 were made in that part of the borehole, which is situated beyond the drift (45 - 97 m). Most of the pressure curves were difficult to interpret. The hydrostatic pressure in the section 89 - 97 m (end of the hole) was calculated to 1,67 Mpa. Near the end of the drift (46.00 - 49.71 m) the pressure was 0.22 Mpa. The permeability tests in Dbh VI were performed by measuring the water-flow and hydrostatic pressure in different levels. The calculated average permeability was 6.5x10 -10 m/s

  11. Realization of station for testing asynchronous three-phase motors

    Science.gov (United States)

    Wróbel, A.; Surma, W.

    2016-08-01

    Nowadays, you cannot imagine the construction and operation of machines without the use of electric motors [13-15]. The proposed position is designed to allow testing of asynchronous three-phase motors. The position consists of a tested engine and the engine running as a load, both engines combined with a mechanical clutch [2]. The value of the load is recorded by measuring shaft created with Strain Gauge Bridge. This concept will allow to study the basic parameters of the engines, visualization motor parameters both vector and scalar controlled, during varying load drive system. In addition, registration during the variable physical parameters of the working electric motor, controlled by a frequency converter or controlled by a contactor will be possible. Position is designed as a teaching and research position to characterize the engines. It will be also possible selection of inverter parameters.

  12. Space Station Environmental Control and Life Support System Test Facility at Marshall Space Flight Center

    Science.gov (United States)

    Springer, Darlene

    1989-01-01

    Different aspects of Space Station Environmental Control and Life Support System (ECLSS) testing are currently taking place at Marshall Space Flight Center (MSFC). Unique to this testing is the variety of test areas and the fact that all are located in one building. The north high bay of building 4755, the Core Module Integration Facility (CMIF), contains the following test areas: the Subsystem Test Area, the Comparative Test Area, the Process Material Management System (PMMS), the Core Module Simulator (CMS), the End-use Equipment Facility (EEF), and the Pre-development Operational System Test (POST) Area. This paper addresses the facility that supports these test areas and briefly describes the testing in each area. Future plans for the building and Space Station module configurations will also be discussed.

  13. Photovoltaic power generation field test at Saigo Police Station (police station in a heavy-snow district); Saigo keisatsusho taiyoko hatsuden field test jigyo (sekisetsu chiku no keisatsusho)

    Energy Technology Data Exchange (ETDEWEB)

    Matsuo, S. [Shimane Prefectural Police Department, Shimane (Japan)

    1997-05-30

    Contents of a fiscal 1996 photovoltaic power generation field test at a police station in a heavy-snow district are reported. The system is on the rooftop of the garage of Saigo Police Station, Saigo-cho, Shimane Prefecture, and is used for lighting, airconditioning, etc., in the police station. It is 15kW in capacity and operates on high-voltage interconnection (with back flow). The array is a 9-series/17-parallel (polycrystalline modules) system, facing 15deg eastward from due south and inclined at an angle of elevation of 17deg. Dead space on the roof is used for solar cell installation, and the applicability and stability of the photovoltaic power generation system, as installed at a police station in a heavy-snow district, were verified and, at the same, operation data were collected. The data will serve as guidelines for construction in the future, and will enable understanding about how a distributed type power generation plant should be on an isolated island. The compilation of various data about its system interconnection (with back flow) with the commercial power source is meaningful because it will work effectively in popularizing the photovoltaic power generation system. Efforts to appeal to the local population are under way, which includes letting visitors into a terrace, distributing advertising pamphlets, etc., which are quite effective in enlightening people of the new energy producing technology

  14. Pathomechanisms of sciatica in lumbar disc herniation: effect of periradicular adhesive tissue on electrophysiological values by an intraoperative straight leg raising test.

    Science.gov (United States)

    Kobayashi, Shigeru; Takeno, Kenichi; Yayama, Takafumi; Awara, Kousuke; Miyazaki, Tsuyoshi; Guerrero, Alexander; Baba, Hisatoshi

    2010-10-15

    This study is aimed to investigate the changes of nerve root functions during the straight leg raising (SLR) test in vivo. To investigate the relationship between nerve root movement and the electrophysiological values during an intraoperative SLR test. The SLR test is one of the most significant signs for making a clinical diagnosis of lumbar disc herniation. A recent study showed that intraradicular blood flow apparently decreased during the SLR test in patients with disc herniation. The study included 32 patients who underwent microdiscectomy. During the surgery, the nerve root motion affected by the hernia was observed during the SLR test. The patients' legs were allowed to hang down to the angle at which sciatica had occurred and the change of nerve root action potentials was measured. After removal of the hernia, a similar procedure was repeated. The periradicular specimens collected during surgery were examined by light and electron microscope. In all patients intraoperative microscopy revealed that the hernia was adherent to the dura mater of the nerve roots. During the SLR test, the limitation of nerve root movement occurred by periradicular adhesive tissue and amplitude of action potential showed a sharp decrease at the angle that produced sciatica. After removal of the hernia, all the patients showed smooth gliding of the nerve roots during the test, and there was no marked decrease of amplitude. Our data suggest that temporary ischemic changes in the nerve root cause transient conduction disturbances. Pathologic examination showed that the periradicular tissue consisted of the granulation with vascularization and many inflammatory cell infiltrations. The presence of periradicular fibrosis will compound the nerve root pain by fixing the nerve in one position, thereby increasing the susceptibility of the nerve root to tension or compression.

  15. Microwave energy transmission test toward the SPS using the space station

    Energy Technology Data Exchange (ETDEWEB)

    Kaya, N.; Matsumoto, H.; Miyatake, S.; Kimura, I.; Nagatomo, M.

    1986-12-01

    An outline of a project METT (Microwave Energy Transmission Test) using the Space Station is described. The objectives of the METT are to develop and test the technology of microwave energy transmission for the future Solar Power Satellite (SPS), and to estimate the environmental effects of the high power microwaves on the ionosphere and the atmosphere. Energy generated with solar cells is transmitted from a transmitting antenna on the bus platform near the Space Station to a rectenna on the sub-satellite or the ground station in order to test the total efficiency and the functions of the developed system of the energy transmission. Plasma similar to that in the D and E layers in the ionosphere is produced in a large balloon opened on the sub-satellite in order to investigate possible interactions between the SPS microwave and the ionospheric plasma and to determine the maximum power density of the microwave beam which passes through the ionosphere.

  16. Comprehensive Test Ban Treaty (CTBT) monitoring station operating regime influence on radionuclide detection sensitivity

    International Nuclear Information System (INIS)

    Williams, D.L.

    1999-01-01

    International Monitoring System (IMS) stations are being deployed worldwide in support of the Comprehensive [Nuclear] Test Ban Treaty (CTBT). The highly sensitive radionuclide monitoring stations regularly sample airborne radionuclide particulates to determine whether fission products are present in the atmosphere that may be indicative of a nuclear weapons test. Standards have been set for these stations regarding their operation regime and the minimum detectable concentrations (MDCs) for specific radionuclides likely to be present after a nuclear weapons test. This study uses actual CTBT monitoring data to relate a subset of the specified operational standards with the listed MDC limits. It is determined that a relationship exists between the specified operational regime and the MDC values. Since the background radioactivity is largely a function of the radon and thoron progeny, longer decay operational regimes allow for a reduction in the background. For longer lived radionuclides, this corresponds to a reduction in MDC. (author)

  17. Realisation and instrumentation of high current power station for superconducting cables testing

    International Nuclear Information System (INIS)

    Regnaud, S.

    2000-05-01

    This report deals with the designing of a high current station able to test electric properties of superconductors. This test station will be used for testing the superconducting wires of large hadron collider detectors in CERN. The high current test station will have to generate high intensity continuous current in a magnetic field of 0 to 5 tesla and in temperature conditions of 4.2 K. The length of wire samples submitted to the uniform magnetic field is 300 mm and the installation is fitted with equipment able to measure the magnetic field perpendicular to either faces of the wire. The peculiarity of this station is to use a superconducting transformer in order to generate the high current. The first part of this work recalls important notions concerning superconductivity. The second part presents the high current station by describing the superconducting transformer and the sample-holder. We have studied the designing of a transformer able to yield a secondary current whose intensity reaches 100 kA, such intensity generates powerful electromagnetic forces (566 kN/m) in case of defect, so the sample-holder has to be carefully design to bear them. The third part presents the cryogenic component of the station, the instrumentation of the sample-holder and the method used to measure secondary currents. In the last part we present the performance of a prototype transformer, this prototype is able to deliver a 22 kA secondary current for a 160 A primary current, the uncertainty on the measured value of the secondary current is about 3%

  18. Research on efficiency test of a turbine in Khan Khwar hydropower station

    International Nuclear Information System (INIS)

    Zhang, H K; Liang, Z; Deng, M G; Liu, X B; Wang, H Y; Liu, D M

    2012-01-01

    The efficiency test is an important indicator to evaluate the energy conversion performance of a hydraulic turbine. For hydropower stations which do not have the direct flow measurement conditions, whether the characteristic curve of a turbine obtained through similarity theory conversion by using the comprehensive characteristic curve of the turbine can correctly reflect the operating performance of the prototype unit is a key issue in this industry. By taking the No.1 unit of Khan Khwar hydropower station as the example, the efficiency test of this turbine was studied on the site, including the measurement method of test parameters, the configuration of the computer test system, as well as the processing and analysis of test data.

  19. Excessive daytime sleepiness in adult patients with ADHD as measured by the Maintenance of Wakefulness Test, an electrophysiologic measure.

    Science.gov (United States)

    Bioulac, Stéphanie; Chaufton, Cyril; Taillard, Jacques; Claret, Astrid; Sagaspe, Patricia; Fabrigoule, Colette; Bouvard, Manuel P; Philip, Pierre

    2015-07-01

    To quantify the objective level of sleepiness in adult attention-deficit/hyperactivity disorder (ADHD) patients and to determine the relationship between excessive daytime sleepiness and simulated driving performance. Forty adult ADHD patients (DSM-IV criteria) and 19 matched healthy control subjects were included between June 30, 2010, and June 19, 2013. All participants completed the Epworth Sleepiness Scale and the Manchester Driving Behavior Questionnaire. After nocturnal polysomnography, they performed 2 neuropsychological tests, a 4 × 40-minute Maintenance of Wakefulness Test, and a 1-hour driving session. The primary outcome measure was the mean sleep latency on the Maintenance of Wakefulness Test. ADHD patients were divided into 3 groups defined by their Maintenance of Wakefulness Test scores. Participants (patients and control subjects) were allocated as follows: sleepy ADHD (0-19 min), intermediate ADHD (20-33 min), alert ADHD (34-40 min), and control group (34-40 min). The driving performance outcome was the mean standard deviation of lateral position of the vehicle during the simulated session. The group mean (SD) Epworth Sleepiness Scale score was higher in ADHD patients (12.1 [4.4]) than in controls (6.0 [2.7]) (P driving performance compared to the other 3 groups (P driving performance. Excessive daytime sleepiness, therefore, may be a key element needed to better evaluate these ADHD patients. ClinicalTrials.gov identifier: NCT01160874. © Copyright 2015 Physicians Postgraduate Press, Inc.

  20. On Dimensions of OTA Setups for Massive MIMO Base Stations Radiated Testing

    DEFF Research Database (Denmark)

    Kyösti, Pekka; Fan, Wei; Pedersen, Gert F.

    2016-01-01

    The development of base stations (BS) with large aperture antenna arrays, enabled partially by the utilization of cmWave and mmWave frequency bands, will require radiated testing in fading conditions. In this paper, the objective is to investigate the suitable measurement distances and physical...

  1. Space station environmental control and life support systems test bed program - an overview

    Science.gov (United States)

    Behrend, Albert F.

    As the National Aeronautics and Space Administration (NASA) begins to intensify activities for development of the Space Station, decisions must be made concerning the technical state of the art that will be baselined for the initial Space Station system. These decisions are important because significant potential exists for enhancing system performance and for reducing life-cycle costs. However, intelligent decisions cannot be made without an adequate assessment of new and ready technologies, i.e., technologies which are sufficiently mature to allow predevelopment demonstrations to prove their application feasibility and to quantify the risk associated with their development. Therefore, the NASA has implemented a technology development program which includes the establishment of generic test bed capabilities in which these new technologies and approaches can be tested at the prototype level. One major Space Station subsystem discipline in which this program has been implemented is the environmental control and life support system (ECLSS). Previous manned space programs such as Gemini, Apollo, and Space Shuttle have relied heavily on consumables to provide environmental control and life support services. However, with the advent of a long-duration Space Station, consumables must be reduced within technological limits to minimize Space Station resupply penalties and operational costs. The use of advanced environmental control and life support approaches involving regenerative processes offers the best solution for significant consumables reduction while also providing system evolutionary growth capability. Consequently, the demonstration of these "new technologies" as viable options for inclusion in the baseline that will be available to support a Space Station initial operational capability in the early 1990's becomes of paramount importance. The mechanism by which the maturity of these new regenerative life support technologies will be demonstrated is the Space

  2. Space Station Freedom environmental control and life support system phase 3 simplified integrated test detailed report

    Science.gov (United States)

    Roberts, B. C.; Carrasquillo, R. L.; Dubiel, M. Y.; Ogle, K. Y.; Perry, J. L.; Whitley, K. M.

    1990-01-01

    A description of the phase 3 simplified integrated test (SIT) conducted at the Marshall Space Flight Center (MSFC) Core Module Integration Facility (CMIF) in 1989 is presented. This was the first test in the phase 3 series integrated environmental control and life support systems (ECLSS) tests. The basic goal of the SIT was to achieve full integration of the baseline air revitalization (AR) subsystems for Space Station Freedom. Included is a description of the SIT configuration, a performance analysis of each subsystem, results from air and water sampling, and a discussion of lessons learned from the test. Also included is a full description of the preprototype ECLSS hardware used in the test.

  3. Corrective Action Plan for Corrective Action Unit 490: Station 44 Burn Area, Tonopah Test Range, Nevada

    Energy Technology Data Exchange (ETDEWEB)

    K. B. Campbell

    2002-04-01

    Corrective Action Unit (CAU) 490, Station 44 Burn Area is located on the Tonopah Test Range (TTR). CAU 490 is listed in the Federal Facility Agreement and Consent Order (FFACO, 1996) and includes for Corrective Action Sites (CASs): (1) Fire Training Area (CAS 03-56-001-03BA); (2) Station 44 Burn Area (CAS RG-56-001-RGBA); (3) Sandia Service Yard (CAS 03-58-001-03FN); and (4) Gun Propellant Burn Area (CAS 09-54-001-09L2).

  4. Corrective action decision document, Second Gas Station, Tonopah test range, Nevada (Corrective Action Unit No. 403)

    International Nuclear Information System (INIS)

    1997-11-01

    This Corrective Action Decision Document (CADD) for Second Gas Station (Corrective Action Unit [CAU] No. 403) has been developed for the U.S. Department of Energy's (DOE) Nevada Environmental Restoration Project to meet the requirements of the Federal Facility Agreement and Consent Order (FFACO) of 1996 as stated in Appendix VI, open-quotes Corrective Action Strategyclose quotes (FFACO, 1996). The Second Gas Station Corrective Action Site (CAS) No. 03-02-004-0360 is the only CAS in CAU No. 403. The Second Gas Station CAS is located within Area 3 of the Tonopah Test Range (TTR), west of the Main Road at the location of former Underground Storage Tanks (USTs) and their associated fuel dispensary stations. The TTR is approximately 225 kilometers (km) (140 miles [mi]) northwest of Las Vegas, Nevada, by air and approximately 56 km (35 mi) southeast of Tonopah, Nevada, by road. The TTR is bordered on the south, east, and west by the Nellis Air Force Range and on the north by sparsely populated public land administered by the Bureau of Land Management and the U.S. Forest Service. The Second Gas Station CAS was formerly known as the Underground Diesel Tank Site, Sandia Environmental Restoration Site Number 118. The gas station was in use from approximately 1965 to 1980. The USTs were originally thought to be located 11 meters (m) (36 feet [ft]) east of the Old Light Duty Shop, Building 0360, and consisted of one gasoline UST (southern tank) and one diesel UST (northern tank) (DOE/NV, 1996a). The two associated fuel dispensary stations were located northeast (diesel) and southeast (gasoline) of Building 0360 (CAU 423). Presently the site is used as a parking lot, Building 0360 is used for mechanical repairs of vehicles

  5. Suppressing Unwanted Autobiographical Memories Reduces Their Automatic Influences: Evidence From Electrophysiology and an Implicit Autobiographical Memory Test.

    Science.gov (United States)

    Hu, Xiaoqing; Bergström, Zara M; Bodenhausen, Galen V; Rosenfeld, J Peter

    2015-07-01

    The present study investigated the extent to which people can suppress unwanted autobiographical memories in a memory-detection context involving a mock crime. Participants encoded sensorimotor-rich memories by enacting a lab-based crime (stealing a ring) and received instructions to suppress memory of the crime in order to evade guilt detection in a brain-wave-based concealed-information test. Aftereffects of suppression on automatic memory processes were measured in an autobiographical Implicit Association Test. Results showed that suppression attenuated brain-wave activity (the P300) associated with crime-relevant memory retrieval, which rendered waveforms from innocent and guilty participants indistinguishable. However, the two groups could nevertheless be discriminated via the late-posterior-negative slow wave, which may reflect the need to monitor response conflict arising between voluntary suppression and automatic recognition processes. Finally, extending recent findings that suppression can impair implicit memory processes, we provide novel evidence that suppression reduces automatic cognitive biases often associated with actual autobiographical memories. © The Author(s) 2015.

  6. Strength assessment of a cryostat used by the hollow electron test station.

    CERN Document Server

    Efremov, Filip

    2015-01-01

    The following report explains the work I have done on my summer student work project and the experience I have gained during the process. The work consisted of a strength assessment of a cryogenic vacuum insulated vessel according to European regulations. The cryogenic vacuum insulated vessel is used for the cooling of the solenoids. The solenoids are used in the hollow electron test station and create the magnetic fields used for testing electron guns and validating the concept of a hollow electron lens.

  7. Signal Processing for Indian and Pakistan Nuclear Tests Recorded at IMS Stations Located in Israel

    Science.gov (United States)

    Gitterman, Y.; Pinsky, V.; Hofstetter, R.

    - In compliance with the Comprehensive Nuclear-Test-Ban-Treaty (CTBT) the International Monitoring System (IMS) was designed for detection and location of the clandestine Nuclear Tests (NT). Two auxiliary IMS seismic stations MRNI and EIL, deployed recently, were subjected to detectability, travel-time calibration and discrimination analysis. The study is based on the three recent 1998 underground nuclear explosions: one of India and two of Pakistan, which provided a ground-truth test of the existing IMS. These events, attaining magnitudes of 5.2, 4.8 and 4.6 correspondingly, were registered by many IMS and other seismic stations.The MRNI and EIL broadband (BB) stations are located in Israel at teleseismic distances (from the explosions) of 3600, 2800 and 2700km, respectively, where the signals from the tests are already weak. The Indian and the second Pakistan NT were not detected by the short-period Israel Seismic Network (ISN), using standard STA/LTA triggering. Therefore, for the chosen IMS stations we compare the STA/LTA response to the results of the more sensitive Murdock-Hutt (MH) and the Adaptive Statistically Optimal Detector (OD) that showed triggering for these three events. The second Pakistan NT signal arrived at the ISN and the IMS stations in the coda of a strong Afghanistan earthquake and was further disturbed by a preceding signal from a local earthquake. However, the NT signal was successfully extracted at EIL and MRNI stations using MH and OD procedures. For comparison we provide the signal analysis of the cooperating BB station JER, with considerably worse noise conditions than EIL and MRNI, and show that OD can detect events when the other algorithms fail. Using the most quiet EIL station, the most sensitive OD and different bandpass filters we tried in addition to detect the small Kazakh chemical 100-ton calibration explosion of 1998, with magnitude 3.7 at a distance approaching 4000km. The detector response curve showed uprising in the

  8. A Low Heat Inleak Cryogenic Station for Testing HTS Current Leads for the Large Hadron Collider

    CERN Document Server

    Ballarino, A; Gomes, P; Métral, L; Serio, L; Suraci, A

    1999-01-01

    The LHC will be equipped with about 8000 superconducting magnets of all types. The total current to be transported into the cryogenic enclosure amounts to some 3360 kA. In order to reduce the heat load into the liquid helium, CERN intends to use High Temperature Superconducting (HTS) material for leads having current ratings up to 13 kA. The resistive part of the leads is cooled by forced flow of gaseous helium between 20 K and 300 K. The HTS part of the lead is immersed in a 4.5 K liquid helium bath, operates in self cooling conditions and is hydraulically separated from the resistive part. A cryogenic test station has been designed and built in order to assess the thermal and electrical performances of 13 kA prototype current leads. We report on the design, commissioning and operation of the cryogenic test station and illustrate its performance by typical test results of HTS current leads.

  9. Finite element analysis of an underground protective test station subjected to severe ground motion

    International Nuclear Information System (INIS)

    Burchett, S.N.; Milloy, J.A.; Von Riesemann, W.A.

    1974-01-01

    A recoverable test station, to be used at a location very close to the detonation point of an underground nuclear test, was designed and tested. The design required that the station survive the very severe free-field stress and that the acceleration of the station be limited to a tolerable level. The predicted magnitude and time history of the free-field stress and acceleration indicated that the volcanic tuff medium and the materials of the proposed structure would exhibit nonlinear behavior, so that a transient dynamic analysis of a composite type structure involving nonlinear materials and large deformations was necessary. Parameter studies using a linear elastic dynamic finite element technique were first done to gain an understanding of the effect of the material properties and to study the response of various configurations of the protective structure to the transient loading. Based upon the results of these parameter studies and upon fielding considerations, a tentative design was chosen. This design was then evaluated using a newly developed finite element computer program. The results obtained from this analysis are compared to the field test results. (U.S.)

  10. Hot Cell Installation and Demonstration of the Severe Accident Test Station

    Energy Technology Data Exchange (ETDEWEB)

    Linton, Kory D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Burns, Zachary M. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrani, Kurt A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Yan, Yong [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-08-01

    A Severe Accident Test Station (SATS) capable of examining the oxidation kinetics and accident response of irradiated fuel and cladding materials for design basis accident (DBA) and beyond design basis accident (BDBA) scenarios has been successfully installed and demonstrated in the Irradiated Fuels Examination Laboratory (IFEL), a hot cell facility at Oak Ridge National Laboratory. The two test station modules provide various temperature profiles, steam, and the thermal shock conditions necessary for integral loss of coolant accident (LOCA) testing, defueled oxidation quench testing and high temperature BDBA testing. The installation of the SATS system restores the domestic capability to examine postulated and extended LOCA conditions on spent fuel and cladding and provides a platform for evaluation of advanced fuel and accident tolerant fuel (ATF) cladding concepts. This document reports on the successful in-cell demonstration testing of unirradiated Zircaloy-4. It also contains descriptions of the integral test facility capabilities, installation activities, and out-of-cell benchmark testing to calibrate and optimize the system.

  11. Start-up test of Fukushima Daini Nuclear Power Station Unit No.3

    International Nuclear Information System (INIS)

    Inomata, Toshio; Umezu, Akira; Kajikawa, Makoto; Koibuchi, Hiroshi; Netsu, Nobuhiko.

    1986-01-01

    In Unit 3 of the Fukushima Nuclear Power Station II (daini), a BWR power plant of output 1,100 MW, commercial operation was started in June 1985. Its start-up test was finished successfully in about nine months. That is, new equipments introduced were demonstration tested. Though the items of testing are increased, the start-up test took short time, resulting in construction period only 54.7 months of the Unit 3, the shortest in the world. During the test, there was no scramming other than the planned. Described are the following: an outline of the Unit 3, the items of its improvement and standardization, including the new equipments, preparations for the start-up test, the start-up test and its evaluation. (Mori, K.)

  12. An environmental testing facility for Space Station Freedom power management and distribution hardware

    Science.gov (United States)

    Jackola, Arthur S.; Hartjen, Gary L.

    1992-01-01

    The plans for a new test facility, including new environmental test systems, which are presently under construction, and the major environmental Test Support Equipment (TSE) used therein are addressed. This all-new Rocketdyne facility will perform space simulation environmental tests on Power Management and Distribution (PMAD) hardware to Space Station Freedom (SSF) at the Engineering Model, Qualification Model, and Flight Model levels of fidelity. Testing will include Random Vibration in three axes - Thermal Vacuum, Thermal Cycling and Thermal Burn-in - as well as numerous electrical functional tests. The facility is designed to support a relatively high throughput of hardware under test, while maintaining the high standards required for a man-rated space program.

  13. Field testing of behavioral barriers for cooling water intake structures -test site 1 - Pickering Nuclear Generating Station

    International Nuclear Information System (INIS)

    Patrick, P.H.; McKinley, R.S.; Micheletti, W.C.

    1988-01-01

    A multi-year research program was developed by the Electric Power Research Institute to evaluate the effectiveness of selected behavioral systems for fish exclusion at sites representative of different aquatic environments. The first test site was the Pickering Nuclear Generating Station (NGS) located on Lake Ontario which represented the Great Lakes environment. A single pneumatic popper, a low frequency, high amplitude sound deterrent, was found to effectively exclude adult alewife, the principal species impinged at Pickering NGS. An air bubble curtain, used either alone or combined with strobe lights, was not a consistent deterrent. Effectiveness of air bubbles was only enhanced when used in association with a popper. Strobe lights were the least effective of the three devices tested. Operation of all three devices together did not surpass the effectiveness of the popper when used alone. Sound deterrents show promise for fish exclusion at generating stations located on the Great Lakes

  14. Preliminary results for HIP bonding Ta to W targets for the materials test station

    Energy Technology Data Exchange (ETDEWEB)

    Dombrowski, David E [Los Alamos National Laboratory; Maloy, Stuart A [Los Alamos National Laboratory

    2009-01-01

    Tungsten targets for the Materials Test Station (MTS) were clad with thin tantalum cover plates and a tantalum frame using hot isostatic pressing (HIP). A preliminary HIP parameter study showed good bonding and intimate mechanical contact for Ta cover plate thicknesses of 0.25 mm (0.010 inch) and 0.38 mm (0.015 inch). HIP temperatures of full HIP runs were 1500 C (2732 F). HIP pressure was 203 MPa (30 ksi).

  15. Operation of the Hoenoe wind power test station. Final report; Drift av Hoenoe provstation. Slutrapport

    Energy Technology Data Exchange (ETDEWEB)

    Ellsen, Magnus; Carlson, Ola [Chalmers Univ. of Tech., Goeteborg (Sweden). Dept. of Electric Power Engineering

    2002-04-01

    This project has made it possible to have autonomous operation of the Chalmers experimental wind turbine. By development of the optimal speed and stall control the energy production is good. The test station has been put in good order and is well prepared to been shown to visitors. The proposed research will focus on series capacitors for increasing the power output and better control of the damping valves to reduce vibrations.

  16. Optimal test intervals for shutdown systems for the Cernavoda nuclear power station

    International Nuclear Information System (INIS)

    Negut, Gh.; Laslau, F.

    1993-01-01

    Cernavoda nuclear power station required a complete PSA study. As a part of this study, an important goal to enhance the effectiveness of the plant operation is to establish optimal test intervals for the important engineering safety systems. The paper presents, briefly, the current methods to optimize the test intervals. For this reason it was used Vesely methods to establish optimal test intervals and Frantic code to survey the influence of the test intervals on system availability. The applications were done on the Shutdown System no. 1, a shutdown system provided whit solid rods and on Shutdown System no. 2 provided with injecting poison. The shutdown systems receive nine total independent scram signals that dictate the test interval. Fault trees for the both safety systems were developed. For the fault tree solutions an original code developed in our Institute was used. The results, intended to be implemented in the technical specifications for test and operation of Cernavoda NPS are presented

  17. Preliminary Test Results of Heshe Hydrogeological Experimental Well Station in Taiwan

    Science.gov (United States)

    Chuang, P.; Liu, C.; Lin, M.; Chan, W.; Lee, T.; Chia, Y.; Teng, M.; Liu, C.

    2013-12-01

    Safe disposal of radioactive waste is a critical issue for the development of nuclear energy. The design of final disposal system is based on the concept of multiple barriers which integrate the natural barriers and engineering barriers for long-term isolation of radioactive wastes. As groundwater is the major medium that can transport radionuclides to our living environment, it is essential to characterize groundwater flow at the disposal site. Taiwan is located at the boundary between the Eurasian plate and the Philippine Sea plate. Geologic formations are often fractured due to tectonic compression and extension. In this study, a well station for the research and development of hydrogeological techniques was established at the Experimental Forest of the National Taiwan University in central Taiwan. There are 10 testing wells, ranging in depth from 25 m to 100 m, at the station. The bedrock beneath the regolith is highly fractured mudstone. As fracture is the preferential pathway of the groundwater flow, the focus of in-situ tests is to investigate the location of permeable fractures and the connection of permeable fractures. Several field tests have been conducted, including geophysical logging, heat-pulse flowmeter, hydraulic test, tracer test and double packer test, for the development of advanced technologies to detect the preferential groundwater flow in fractured rocks.

  18. The Space Station Module Power Management and Distribution automation test bed

    Science.gov (United States)

    Lollar, Louis F.

    1991-01-01

    The Space Station Module Power Management And Distribution (SSM/PMAD) automation test bed project was begun at NASA/Marshall Space Flight Center (MSFC) in the mid-1980s to develop an autonomous, user-supportive power management and distribution test bed simulating the Space Station Freedom Hab/Lab modules. As the test bed has matured, many new technologies and projects have been added. The author focuses on three primary areas. The first area is the overall accomplishments of the test bed itself. These include a much-improved user interface, a more efficient expert system scheduler, improved communication among the three expert systems, and initial work on adding intermediate levels of autonomy. The second area is the addition of a more realistic power source to the SSM/PMAD test bed; this project is called the Large Autonomous Spacecraft Electrical Power System (LASEPS). The third area is the completion of a virtual link between the SSM/PMAD test bed at MSFC and the Autonomous Power Expert at Lewis Research Center.

  19. Multi-Use seismic stations offer strong deterrent to clandestine nuclear weapons testing

    Science.gov (United States)

    Hennet, C. B.; Van der Vink, G. E.; Richards, P. G.; Adushkin, V. V.; Kopnichev, Y. F.; Geary, R.

    As the United States and other nations push for the signing of a Comprehensive Test Ban Treaty, representatives are meeting in Geneva this year to develop an International Seismic Monitoring System to verify compliance with the treaty's restrictions. In addition to the official monitoring system, regional networks developed for earthquake studies and basic research can provide a strong deterrent against clandestine testing. The recent release of information by the U.S. Department of Energy (DoE) on previously unannounced nuclear tests provides an opportunity to assess the ability of multi-use seismic networks to help monitor nuclear testing across the globe.Here we look at the extent to which the formerly unannounced tests were recorded and identified on the basis of publicly available seismographic data recorded by five seismic networks. The data were recorded by networks in southern Nevada and northern California at stations less than 1500 km from the Nevada Test Site (NTS), and two networks in the former Soviet Union at stations farther than 1500 km from the NTS.

  20. Radiation dose electrophysiology procedures

    International Nuclear Information System (INIS)

    Hernandez-Armas, J.; Rodriguez, A.; Catalan, A.; Hernandez Armas, O.; Luque Japon, L.; Moral, S.; Barroso, L.; Rfuez-Hdez, R.

    2006-01-01

    The aim of this paper has been to measure and analyse some of the parameters which are directly related with the doses given to patients in two electrophysiology procedures: diagnosis and ablation with radiofrequency. 16 patients were considered in this study. 13 them had an ablation with radiofrequency at the Unit of Electrophysiology at the University Hospital of the Canaries, La Laguna., Tenerife. The results of skin doses, in the ablation cases, were higher than 2 Gy (threshold of some deterministic effects). The average value was 1.1 Gy. The personal doses, measured under the lead apron, for physician and nurses were 4 and 3 micro Sievert. These results emphasised the necessity of radiation protection measures in order to reduce, ad much as possible, the doses to patients. (Author)

  1. LHCb: Test Station for the LHCb Muon Front-End Electronic

    CERN Multimedia

    Polycarpo, E

    2005-01-01

    The LHCb Muon Group has developed the CMOS ASIC CARIOCA to readout its Multiwire Proportional Chambers (MWPC) and GEM detectors, using a rad-hard IBM 0.25um process. Each ASIC holds 8 identical current-mode ASDB channels with individual input thresholds. The Muon detector contains around 120000 physical channels, requiring production of 20000 front-end chips, roughly. CARIOCA has been developed to process MWPC cathode and anode signals and two different versions have been implemented to overcome the requirement of MWP and GEM chambers operation. The test station has been devised to accomplish bipolar tests and to measure characteristics of both CARIOCA versions.

  2. Local control station for development, testing and maintenance of mirror fusion facility subsystem controls

    International Nuclear Information System (INIS)

    Ables, E.; Kelly, M.F.

    1985-01-01

    A Local Control Station (LCS) was designed and built to provide a simplified ad easily configurable means of controlling any Mirror Fusion Test Facility (MFTF-B) subsystem for the purpose of development, testing and maintenance of the subsystem. All MFTF-B Subsystems incorporate at least one Local Control Computer (LCC) that is connected to and accepts high level commands from one of the Supervisory Control and Diagnostic System (SCDS) computers. The LCS connects directly to the LCC in place of SCDS. The LCS communicates with the subsystem hardware using the same SCDS commands that the local control computer recognizes and as such requires no special configuration of the LCC

  3. Simulated earthquake testing of naturally aged C and D LCU-13 station battery cells

    International Nuclear Information System (INIS)

    Tulk, J.D.; Black, D.A.; Janis, W.J.; Royce, C.J.

    1985-03-01

    A sample of 10-year-old lead-acid storage batteries from the North Anna Nuclear Power Station (Virginia Electric and Power Company) were tested on a shaker table. Seven cells were subjected to simulated earthquakes with a ZPA of approximately 1.5 g. All seven delivered uninterrupted power during the shaker tests and were able to pass a post-seismic capacity test. Two cells were shaken to higher intensities (ZPA approximately equal to 2 g). These cells provided uninterrupted power during the shaker tests, but had post-seismic capacities that were below the required level for Class1E battery cells. After the tests, several cells were disassembled and examined. Internal components were in good condition with limited oxidization and plate cracking

  4. Start-up tests of Kashiwazakikariwa Nuclear Power Station Unit No.2 and No.5

    International Nuclear Information System (INIS)

    Fueki, Kensuke; Aoki, Shiro; Tanaka, Yasuhisa; Yahagi, Kimitoshi

    1991-01-01

    The Kashiwazakikariwa Nuclear Power Station Units No.5 and No.2 started commercial operation on April 10 and September 28 of 1990 respectively. As the result of the application of the First and Second LWR Improvement and Standardization Program, the plants were designed aiming at improvement of reliability, operation, and maintenance while maintaining safety. Construction of the plants took 6.5 to 7 years for completion, during which period the last 10 months were spent for the start up tests program. Start up tests were carried out under deliberate management to assure that the plants can operate safely and steadily at the prescribed operating points, and the schedules and tests item modifications adopted in Unit No.2 and No.5 were verified under the start up tests program. (author)

  5. Forced vibration tests on the reactor building of a nuclear power station, 1

    International Nuclear Information System (INIS)

    Takeda, Toshikazu; Tsunoda, Tomohiko; Wakamatsu, Kunio; Kaneko, Masataka; Nakamura, Mitsuru; Kunoh, Toshio; Murahashi, Hisahiro

    1988-01-01

    Tsuruga Unit No.2 Nuclear Power Station of the Japan Atomic Power Company is the first PWR-type 4-loop plant constructed in Japan with a prestressed concrete containment vessel (PCCV). This report describes forced vibration tests carried out on the reactor building of this plant. The following were obtained as results: (1) The results of the forced vibration tests corresponded well on the whole with design values. (2) The vibration characteristics of the PCCV observed in the tests after prestressing are no different from the ones before prestressing. This shows that the vibration properties of the PCCV are practically independent of prestressing loads. (3) A seismic response analysis of the design basis earthquake was made on the design model reflecting the test results. The seismic safety of the plant was confirmed by this analysis. (author)

  6. Materials for the field test - students' attitudes to nuclear power stations

    International Nuclear Information System (INIS)

    Hoffmann, L.; Kattmann, U.; Lucht, H.; Spada, H.

    1975-01-01

    This working paper contains all the materials developed for and used in the field test of 'Student Attitudes toward Atomic Power Stations'. This research is a component of a larger project called 'Attitudes and Attitudes Change with Regard to Problems of Energy Supply and their Consequences for our Environment'. A central aim of this project is the development of instrumental strategies enabling the student to build up in this field a critically reflective and active behavior and attitudes based on sound problem consciousness. These instrumental strategies are derived from theories of social, learning and environmental psychology. A concrete result of these efforts are the materials of the field test mentioned above. They include: a) The draft of an instructional unit 'Atomic Power Stations - Prosperity or Disaster' with - a booklet on the subject matter for students and teachers - a paper on the contents of the instructional unit and their sequence - information for the students concerning the aims of the investigation - working materials for the students - reading materials for the teachers informing them about the proposed instructional strategies based on the psychological theories: (1) model-learning and the structuring of knowledge, (2) how to activate and motivate students, (3) the stabilization of attitudes and (4) small group work. b) Instruments for testing and observation. These instruments were used within a criterion-oriented evaluation and for a test of the effects of the different proposed items used in the instruction. (orig./HP) [de

  7. Test and evaluation of load converter topologies used in the Space Station Freedom power management and distribution dc test bed

    Science.gov (United States)

    Lebron, Ramon C.; Oliver, Angela C.; Bodi, Robert F.

    1991-01-01

    Power components hardware in support of the Space Station freedom dc Electric Power System were tested. One type of breadboard hardware tested is the dc Load Converter Unit, which constitutes the power interface between the electric power system and the actual load. These units are dc to dc converters that provide the final system regulation before power is delivered to the load. Three load converters were tested: a series resonant converter, a series inductor switch-mode converter, and a switching full-bridge forward converter. The topology, operation principles, and test results are described, in general. A comparative analysis of the three units is given with respect to efficiency, regulation, short circuit behavior (protection), and transient characteristics.

  8. Free-Suspension Residual Flexibility Testing of Space Station Pathfinder: Comparison to Fixed-Base Results

    Science.gov (United States)

    Tinker, Michael L.

    1998-01-01

    Application of the free-suspension residual flexibility modal test method to the International Space Station Pathfinder structure is described. The Pathfinder, a large structure of the general size and weight of Space Station module elements, was also tested in a large fixed-base fixture to simulate Shuttle Orbiter payload constraints. After correlation of the Pathfinder finite element model to residual flexibility test data, the model was coupled to a fixture model, and constrained modes and frequencies were compared to fixed-base test. modes. The residual flexibility model compared very favorably to results of the fixed-base test. This is the first known direct comparison of free-suspension residual flexibility and fixed-base test results for a large structure. The model correlation approach used by the author for residual flexibility data is presented. Frequency response functions (FRF) for the regions of the structure that interface with the environment (a test fixture or another structure) are shown to be the primary tools for model correlation that distinguish or characterize the residual flexibility approach. A number of critical issues related to use of the structure interface FRF for correlating the model are then identified and discussed, including (1) the requirement of prominent stiffness lines, (2) overcoming problems with measurement noise which makes the antiresonances or minima in the functions difficult to identify, and (3) the use of interface stiffness and lumped mass perturbations to bring the analytical responses into agreement with test data. It is shown that good comparison of analytical-to-experimental FRF is the key to obtaining good agreement of the residual flexibility values.

  9. Free-free and fixed base modal survey tests of the Space Station Common Module Prototype

    Science.gov (United States)

    Driskill, T. C.; Anderson, J. B.; Coleman, A. D.

    1992-01-01

    This paper describes the testing aspects and the problems encountered during the free-free and fixed base modal surveys completed on the original Space Station Common Module Prototype (CMP). The CMP is a 40-ft long by 14.5-ft diameter 'waffle-grid' cylinder built by the Boeing Company and housed at the Marshall Space Flight Center (MSFC) near Huntsville, AL. The CMP modal survey tests were conducted at MSFC by the Dynamics Test Branch. The free-free modal survey tests (June '90 to Sept. '90) included interface verification tests (IFVT), often referred to as impedance measurements, mass-additive testing and linearity studies. The fixed base modal survey tests (Feb. '91 to April '91), including linearity studies, were conducted in a fixture designed to constrain the CMP in 7 total degrees-of-freedom at five trunnion interfaces (two primary, two secondary, and the keel). The fixture also incorporated an airbag off-load system designed to alleviate the non-linear effects of friction in the primary and secondary trunnion interfaces. Numerous test configurations were performed with the objective of providing a modal data base for evaluating the various testing methodologies to verify dynamic finite element models used for input to coupled load analysis.

  10. Space Station propulsion - Advanced development testing of the water electrolysis concept at MSFC

    Science.gov (United States)

    Jones, Lee W.; Bagdigian, Deborah R.

    1989-01-01

    The successful demonstration at Marshall Space Flight Center (MSFC) that the water electrolysis concept is sufficiently mature to warrant adopting it as the baseline propulsion design for Space Station Freedom is described. In particular, the test results demonstrated that oxygen/hydrogen thruster, using gaseous propellants, can deliver more than two million lbf-seconds of total impulse at mixture ratios of 3:1 to 8:1 without significant degradation. The results alao demonstrated succcessful end-to-end operation of an integrated water electrolysis propulsion system.

  11. International Space Station Bacteria Filter Element Post-Flight Testing and Service Life Prediction

    Science.gov (United States)

    Perry, J. L.; von Jouanne, R. G.; Turner, E. H.

    2003-01-01

    The International Space Station uses high efficiency particulate air (HEPA) filters to remove particulate matter from the cabin atmosphere. Known as Bacteria Filter Elements (BFEs), there are 13 elements deployed on board the ISS's U.S. Segment. The pre-flight service life prediction of 1 year for the BFEs is based upon performance engineering analysis of data collected during developmental testing that used a synthetic dust challenge. While this challenge is considered reasonable and conservative from a design perspective, an understanding of the actual filter loading is required to best manage the critical ISS Program resources. Thus testing was conducted on BFEs returned from the ISS to refine the service life prediction. Results from this testing and implications to ISS resource management are discussed. Recommendations for realizing significant savings to the ISS Program are presented.

  12. Test Station for Magnetization Measurements on Large Quantities of Superconducting Strands

    CERN Document Server

    Le Naour, S; Billan, J; Genest, J

    2001-01-01

    In the superconducting main magnets of the Large Hadron Collider (LHC), persistent currents in the superconductor determine the field quality at injection field. For this reason it is necessary to check the magnetization of the cable strands during their production. During four years, this requires measurements of the width of the strand magnetization hysteresis loop at 0.5 T, 1.9 K, at a rate of up to eight samples per day. This paper describes the design, construction and the first results of a magnetization test station built for this purpose. The samples are cooled in a cryostat, with a 2-m long elliptic tail. This tail is inserted in a normal conducting dipole magnet with a field between ± 1.5 T. Racetrack pick-up coils, integrated in the cryostat, detect the voltage due to flux change, which is then integrated numerically. The sample holder can contain eight strand samples, each 20 cm long. The test station operates in two modes: either the sample is fixed while the external field is changed, or the sa...

  13. PWR station blackout transient simulation in the INER integral system test facility

    International Nuclear Information System (INIS)

    Liu, T.J.; Lee, C.H.; Hong, W.T.; Chang, Y.H.

    2004-01-01

    Station blackout transient (or TMLB' scenario) in a pressurized water reactor (PWR) was simulated using the INER Integral System Test Facility (IIST) which is a 1/400 volumetrically-scaled reduce-height and reduce-pressure (RHRP) simulator of a Westinghouse three-loop PWR. Long-term thermal-hydraulic responses including the secondary boil-off and the subsequent primary saturation, pressurization and core uncovery were simulated based on the assumptions of no offsite and onsite power, feedwater and operator actions. The results indicate that two-phase discharge is the major depletion mode since it covers 81.3% of the total amount of the coolant inventory loss. The primary coolant inventory has experienced significant re-distribution during a station blackout transient. The decided parameter to avoid the core overheating is not the total amount of the coolant inventory remained in the primary core cooling system but only the part of coolant left in the pressure vessel. The sequence of significant events during transient for the IIST were also compared with those of the ROSA-IV large-scale test facility (LSTF), which is a 1/48 volumetrically-scaled full-height and full-pressure (FHFP) simulator of a PWR. The comparison indicates that the sequence and timing of these events during TMLB' transient studied in the RHRP IIST facility are generally consistent with those of the FHFP LSTF. (author)

  14. Controlled environmental radioiodine tests at the national reactor testing station. 1965 progress report

    Energy Technology Data Exchange (ETDEWEB)

    Adams, D.R.; Bunch, D.F.; Gammill, W.P.; Hawley, C.A. Jr.; Markee, E.H.; Tiernan, M.W.

    1966-02-01

    The CERT project consists of a series of planned releases of radioiodine over different vegetation and during various meteorological conditions, with the prime objective being to measure the relationships involved in the passage of radioiodine through the air-vegetation-cow-milk-human chain. The results of the first five tests in the series, which started in the spring of 1963 and is continuing, are reported. Each test was conducted under measured meteorological conditions and over prepared sampling and grazing courses. Two tests were made over open-range type vegetation, two over irrigated pastures, and one over snow-covered ground. Two tests were conducted under lapse conditions, two under inversion conditions, and one under neutral conditions. In each case, known quantities of elemental /sup 131/I/sub 2/ were released. Relationships determined included air-grass ratios (deposition velocities) which ranged from 0.1 to 1.0 cm/sec; effective half life of /sup 131/I on grass of 3.5 days and 5.5 days; the time of peak activity in milk at two days following a release; milk-grass ratio (C/1:C/g); total /sup 131/I secreted in milk by cows to that ingested by cows; adult human thyroid uptake fraction (inhalation); and based on a breathing rate of 20 m/sup 3//24 hours, the ratio between infinity mills ingestion dose and infinity inhalation dose for a single release was calculated. Data, descriptions of methods, and calculations are reported. Discussions of resuspension factors and particle sizes and behavior are also included.

  15. Testing various modes of installation for permanent broadband stations in open field environment

    Science.gov (United States)

    Vergne, Jérôme; Charade, Olivier; Arnold, Benoît; Louis-Xavier, Thierry

    2014-05-01

    In the framework of the RESIF (Réseau Sismologique et géodésique Français) project, we plan to install more than one hundred new permanent broadband stations in metropolitan France within the next 6 years. Whenever possible, the sensors will be installed in natural or artificial underground cavities that provide a stable thermal environment. However such places do not exist everywhere and we expect that about half the future stations will have to be set up in open fields. For such sites, we are thus looking for a standard model of hosting infrastructure for the sensors that would be easily replicated and would provide good noise level performances at long periods. Since early 2013, we have been operating a prototype station at Clévilliers, a small location in the sedimentary Beauce plain, where we test three kinds of buried seismic vaults and a down-hole installation. The cylindrical seismic vaults are 3m deep and 1m wide and only differ by the type of coupling between the casing and the concrete slab where we installed insulated Trillium T120PA seismometers. The down-hole installation consists in a 3m deep well hosting a Trillium Posthole seismometer. For reference, another sensor has been installed in a ~50cm deep hole, similarly to the way we test every new potential site. Here we compare the noise level in each infrastructure at different frequencies. We observe quite similar performances for the vertical component recorded in the different wells. Conversely, the noise levels on the horizontal components at periods greater than 10s vary by more than 20dB depending on the installation condition. The best results are obtained in the completely decoupled vault and for the down-hole setting, both showing performances comparable to some of our permanent stations installed in tunnels. The amplitude of the horizontal noise also appears to be highly correlated to wind speed recorded on site, even at long periods. The variable response of each vault to such

  16. Integrated water management system - Description and test results. [for Space Station waste water processing

    Science.gov (United States)

    Elden, N. C.; Winkler, H. E.; Price, D. F.; Reysa, R. P.

    1983-01-01

    Water recovery subsystems are being tested at the NASA Lyndon B. Johnson Space Center for Space Station use to process waste water generated from urine and wash water collection facilities. These subsystems are being integrated into a water management system that will incorporate wash water and urine processing through the use of hyperfiltration and vapor compression distillation subsystems. Other hardware in the water management system includes a whole body shower, a clothes washing facility, a urine collection and pretreatment unit, a recovered water post-treatment system, and a water quality monitor. This paper describes the integrated test configuration, pertinent performance data, and feasibility and design compatibility conclusions of the integrated water management system.

  17. Mobile work station concept for assembly of large space structures (zero gravity simulation tests)

    Science.gov (United States)

    Heard, W. L., Jr.; Bush, H. G.; Wallsom, R. E.; Jensen, J. K.

    1982-03-01

    The concept presented is intended to enhance astronaut assembly of truss structure that is either too large or complex to fold for efficient Shuttle delivery to orbit. The potential of augmented astronaut assembly is illustrated by applying the result of the tests to a barebones assembly of a truss structure. If this structure were assembled from the same nestable struts that were used in the Mobile Work Station assembly tests, the spacecraft would be 55 meters in diameter and consist of about 500 struts. The struts could be packaged in less than 1/2% of the Shuttle cargo bay volume and would take up approximately 3% of the mass lift capability. They could be assembled in approximately four hours. This assembly concept for erectable structures is not only feasible, but could be used to significant economic advantage by permitting the superior packaging feature of erectable structures to be exploited and thereby reduce expensive Shuttle delivery flights.

  18. Test and Evaluation Station (TESt) - A Control System for the ALICE-HMPID Liquid Distribution Prototype

    CERN Document Server

    Maatta, E; CERN. Geneva; Swoboda, Detlef; Lecoeur, G

    1999-01-01

    The sub-detectors and systems in the ALICE experiment [1] are of various types. However, during physics runs, all devices necessary for the operation of the detector must be accessible and controllable through a common computer interface. Throughout all other periods each sub-detector requires maintenance, upgrading or test operation. To this end, an access independant of other sub-detectors must be guaranteed. These basic requirements impose a fair number of constraints on the architecture and components of the Detector Control System (DCS). The purpose of the TESt project consisted in the construction of a stand alone unit for a specific sub-system of an ALICE detector in order to gain first experience with commercial products for detector control. Although the control system includes only a small number of devices and is designed for a particular application, it covers nevertheless all layers of a complete system and can be extended or used in different applications. The control system prototype has been...

  19. Control room inleakage testing using tracer gases at Zion Generating station

    International Nuclear Information System (INIS)

    Lagus, P.L.; Brown, J.H.; Dubois, L.J.; Fleming, K.M.

    1993-01-01

    In order to assess the amount of air inleakage into the Control Room Envelope at Zion Generating Station (ZGS), a series of tracer gas tests using sulfur hexafluoride (SF 6 ) were performed on the Control Room ventilation system (PV system) and the Computer Room/Miscellaneous Area ventilation system (OV system) during February, 1991. Two redundant trains, denoted A and B comprise the PV system. Inleakage was measured for each train. An OV supply duct passes through the Control Room Envelope. Leakage from this duct into the Control Room would constitute air leakage into the Control room Envelope and hence any potential leakage had to be quantified. Each test attempted to measure the contribution (if any) of a particular section of PV return duct or OV supply duct to the total air inleakage into the Control Room. This paper reviews the tracer gas tests. Described here are the control room inleakage testing, HVAC equipment room duct inleakage, purge plenum inleakage, OV duct leakage into the control room envelope, vestibule PV return inleakage, TSC duct inleakage, and cable spreading room inleakage. Conclusions from the testing are presented. 5 refs., 4 figs., 7 tabs

  20. Performance Evaluation of the International Space Station Flow Boiling and Condensation Experiment (FBCE) Test Facility

    Science.gov (United States)

    Hasan, Mohammad; Balasubramaniam, R.; Nahra, Henry; Mackey, Jeff; Hall, Nancy; Frankenfield, Bruce; Harpster, George; May, Rochelle; Mudawar, Issam; Kharangate, Chirag R.; hide

    2016-01-01

    A ground-based experimental facility to perform flow boiling and condensation experiments is built in support of the development of the long duration Flow Boiling and Condensation Experiment (FBCE) destined for operation on board of the International Space Station (ISS) Fluid Integrated Rack (FIR). We performed tests with the condensation test module oriented horizontally and vertically. Using FC-72 as the test fluid and water as the cooling fluid, we evaluated the operational characteristics of the condensation module and generated ground based data encompassing the range of parameters of interest to the condensation experiment to be performed on the ISS. During this testing, we also evaluated the pressure drop profile across different components of the fluid subsystem, heater performance, on-orbit degassing subsystem, and the heat loss from different components. In this presentation, we discuss representative results of performance testing of the FBCE flow loop. These results will be used in the refinement of the flight system design and build-up of the FBCE which is scheduled for flight in 2019.

  1. Boars for breeding: A study of methods of evaluation used at testing stations

    Directory of Open Access Journals (Sweden)

    Elsi Ettala

    1973-01-01

    Full Text Available The phenotype testing of highly selected boars was studied. Two groups, each of 30 boars, were tested centrally at stations for growth rate and ultrasonically measured fat thickness. According to test points, made up of a combination of these two traits, the 5 best boars, 5 average boars and the 5 poorest boars where selected for progeny evaluation. In all 26 boars and 441 progeny were tested. The progeny evaluation showed that ultrasonic measurement of the fat thickness of the boars gave a very reliable estimate of the meatiness of their progeny. Those boars, as a group, giving the poorest carcass quality could be distinguished with statistical reliability from the other groups. The correlations between sires and progeny were significant for both daily gain (period 20—88 kg and feed efficiency. The importance of rate of growth and feed efficiency has been neglected in selection for breeding as the test points used for the selection of boars depended almost entirely on fat thickness. More than 30 % of both boars and progeny boars suffered from some form of difficulty in walking. 13 % of the boars were eliminated because of leg faults. Leg faults in progeny were mainly inherited or caused through injury. A phenotype evaluation of progeny boars accounts much more effectively for the variation in their carcass value than does a full barrow sib evaluation alone. For best results, a progeny boar phenotype evaluation should be combined with a full barrow sib evaluation.

  2. Test study on safety features of station blackout accident for nuclear main pump

    International Nuclear Information System (INIS)

    Liu Xiajie; Wang Dezhong; Zhang Jige; Liu Junsheng; Yang Zhe

    2009-01-01

    The theoretical and experimental studies of reactor coolant pump accidents encountered nation-wide and world-wide were described. To investigate the transient hydrodynamic performance of reactor coolant pump (RCP) during the period of rotational inertia in the station blackout accident, some theoretical and experimental studies were carried out, and the analysis of the test results was presented. The experiment parameters, conditions and test methods were introduced. The flow-rate, rotate speed and vibrations were analyzed emphatically. The quadruplicate polynomial curve equation was used to simulate the flow-rate,rotate speed along with time. The test results indicate that the flow-rate and rotator speed decrease rapidly at the very beginning of cut power and the test results accord with the regulation of safety standard. The vibrant displacement of bearing seat is intensified at the moment of lose power, but after a certain period rotor shaft libration changes. The test and analysis results help to understand the hydrodynamic performance of nuclear primary pump under lost of power accident, and provide the basic reference for safety evaluation. (authors)

  3. The Electrophysiological Phenomenon of Alzheimer's Disease: A Psychopathology Theory.

    Science.gov (United States)

    Holston, Ezra C

    2015-08-01

    The current understanding of Alzheimer's disease (AD) is based on the Aβ and tau pathology and the resulting neuropathological changes, which are associated with manifested clinical symptoms. However, electrophysiological brain changes may provide a more expansive understanding of AD. Hence, the objective of this systematic review is to propose a theory about the electrophysiological phenomenon of Alzheimer's disease (EPAD). The review of literature resulted from an extensive search of PubMed and MEDLINE databases. One-hundred articles were purposively selected. They provided an understanding of the concepts establishing the theory of EPAD (neuropathological changes, neurochemical changes, metabolic changes, and electrophysiological brain changes). Changes in the electrophysiology of the brain are foundational to the association or interaction of the concepts. Building on Berger's Psychophysical Model, it is evident that electrophysiological brain changes occur and affect cortical areas to generate or manifest symptoms from onset and across the stages of AD, which may be prior to pathological changes. Therefore, the interaction of the concepts demonstrates how the psychopathology results from affected electrophysiology of the brain. The theory of the EPAD provides a theoretical foundation for appropriate measurements of AD without dependence on neuropathological changes. Future research is warranted to further test this theory. Ultimately, this theory contributes to existing knowledge because it shows how electrophysiological changes are useful in understanding the risk and progression of AD across the stages.

  4. Electrophysiologic Findings and Pain in Carpal Tunnel Syndrome

    Directory of Open Access Journals (Sweden)

    Hava Dönmez Keklikoğlu

    2009-12-01

    Full Text Available OBJECTIVE: Carpal tunnel syndrome (CTS is defined as median nerve entrapment within the carpal tunnel at the wrist. Pain and paresthesia are the most common presenting symptoms of the patients. In this study, our aim was to identify the association between intensity of presenting symptoms and electrophysiologic findings in patients referred to the electrophysiology laboratory with prediagnosis of CTS. METHODS: Sixty-two consecutive patients who were referred to the electrophysiology laboratory with the diagnosis of CTS were enrolled in the study. The intensity of pain was determined by visual analog scale, the findings of Tinel-Phalen tests were assessed, and clinico-demographic findings were recorded. Nerve conduction studies were performed bilaterally in median and ulnar nerves. The severity of CTS was determined with electrophysiologic evaluation, and the association between electrophysiologic findings and symptoms were analyzed statistically. RESULTS: Sixty-two (57 female, 5 male patients were examined in the study. CTS was bilateral in 53 patients and unilateral in 9 patients (total 115 hands. Mean pain score was 5.78 ± 3.50. In 28 hands with a clinical diagnosis of CTS, no electrophysiologic CTS findings were found, whereas in 32 hands mild, in 41 hands moderate and in 14 hands severe findings were obtained. CONCLUSION: According to our study, there was no statistically significant association between severity of symptoms and severity of electrophysiologic findings in CTS

  5. Electrophysiology of Axonal Constrictions

    Science.gov (United States)

    Johnson, Christopher; Jung, Peter; Brown, Anthony

    2013-03-01

    Axons of myelinated neurons are constricted at the nodes of Ranvier, where they are directly exposed to the extracellular space and where the vast majority of the ion channels are located. These constrictions are generated by local regulation of the kinetics of neurofilaments the most important cytoskeletal elements of the axon. In this paper we discuss how this shape affects the electrophysiological function of the neuron. Specifically, although the nodes are short (about 1 μm) in comparison to the distance between nodes (hundreds of μm) they have a substantial influence on the conduction velocity of neurons. We show through computational modeling that nodal constrictions (all other features such as numbers of ion channels left constant) reduce the required fiber diameter for a given target conduction velocity by up to 50% in comparison to an unconstricted axon. We further show that the predicted optimal fiber morphologies closely match reported fiber morphologies. Supported by The National Science Foundation (IOS 1146789)

  6. IEEE standard criteria for type tests of class 1E modules used in nuclear power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1977-01-01

    The Institute of Electrical and Electronics Engineers has generated this document to provide direction for type testing Class 1E modules and obtaining specific type test data. It supplements IEEE Std 323-1974, Standard for Qualifying Class 1E Equipment for Nuclear Power Generating Stations, which describes the basic requirements for Class 1E equipment qualification. Adherence to this document alone may not suffice for assuring public health and safety because it is the integrated performance of the structures, the fluid systems, the electrical systems, the instrumentation systems of the station, and in particular, the plant protection system of which these modules are a part that prevents accidents or limits the consequences of accidents. Each applicant to the Nuclear Regulatory Commission for a license to operate a nuclear power generating station has the responsibility to assure himself and others that this document, if used, is pertinent to his application and that the integrated performance of his station is adequate

  7. Evaluating Diagnostic Value of Electrophysiological Testing (EMG-NCV Compared to the Activity Level of Acetylcholinesterase in Serum and Red Blood Cells of Patients with Moderate to Severe Organophosphate Poisoning

    Directory of Open Access Journals (Sweden)

    Fares Najari

    2017-05-01

    Full Text Available Background Organophosphate compounds cause poisoning and death more than any other insecticide. These toxins can cause peripheral neuropathy which is delayed for about 3 - 6 weeks and no method has been known for predicting the incidence. It has been claimed that electrophysiological tests (EMG - NCV can help in predicting the disorder. Objectives The main purpose of this research was to study EMG - NCV tests in patients with moderate to severe organophosphate poisoning. Methods This was a cross-sectional study conducted on patients with moderate to severe organophosphate poisoning from 2014 to 2016 in Imam Reza hospital of Mashhad. The minimum sample size was calculated as 68 patients and then all data was collected on the basis of inclusion and exclusion criteria using data collection form designed by the researcher, and finally data were analyzed using SPSS V.21 software, descriptive tests (including mean, median, mode and analytical tests (K square, ANOVA. Results Of all 78 patients with the mean age of 27.50 ± 10.0, 45 were female and the rest were male. Totally 29.5% of the patients had abnormal EMG - NCV. Although no significant differences were observed between electro diagnostic tests (EMG - NCV and age, gender, clinical symptoms and levels of acetylcholinesterase serum activity, the relationship between EMG - NCV and RBC levels of acetylcholinesterase activity was significant. Conclusions Electrophysiological tests are not associated with clinical symptoms (muscle weakness and they cannot be considered as a determining factor to discharge the patients; therefore, careful examination of the patients or evaluating the level of AChE activity in red blood cells is needed.

  8. The network architecture and site test of DCIS in Lungmen nuclear power station

    International Nuclear Information System (INIS)

    Lee, C. K.

    2006-01-01

    The Lungmen Nuclear Power Station (LMNPS) is located in North-Eastern Seashore of Taiwan. LMNPP has two units. Each unit generates 1350 Megawatts. It is the first ABWR Plant in Taiwan and is under-construction now. Due to contractual arrangement, there are seven large I and C suppliers/designers, which are GE NUMAC, DRS, Invensys, GEIS, Hitachi, MHI, and Stone and Webster company. The Distributed Control and Information System (DCIS) in Lungmen are fully integrated with the state-of-the-art computer and network technology. General Electric is the leading designer for integration of DCIS. This paper presents Network Architecture and the Site Test of DCIS. The network architectures are follows. GE NUMAC System adopts the point to point architecture, DRS System adopts Ring type architecture with SCRAMNET protocol, Inevnsys system adopts IGiga Byte Backbone mesh network with Rapid Spanning Tree Protocol, GEIS adopts Ethernet network with EGD protocol, Hitachi adopts ring type network with proprietary protocol. MHI adopt Ethernet network with UDP. The data-links are used for connection between different suppliers. The DCIS architecture supports the plant automation, the alarm prioritization and alarm suppression, and uniform MMI screen for entire plant. The Test Program regarding the integration of different network architectures and Initial DCIS architecture Setup for 161KV Energization will be discussed. Test tool for improving site test schedule, and lessons learned from FAT will be discussed too. And conclusions are at the end of this paper. (authors)

  9. The network architecture and site test of DCIS in Lungmen nuclear power station

    Energy Technology Data Exchange (ETDEWEB)

    Lee, C. K. [Instrument and Control Section, Lungmen Nuclear Power Station, Taiwan Power Company, Taipei County Taiwan (China)

    2006-07-01

    The Lungmen Nuclear Power Station (LMNPS) is located in North-Eastern Seashore of Taiwan. LMNPP has two units. Each unit generates 1350 Megawatts. It is the first ABWR Plant in Taiwan and is under-construction now. Due to contractual arrangement, there are seven large I and C suppliers/designers, which are GE NUMAC, DRS, Invensys, GEIS, Hitachi, MHI, and Stone and Webster company. The Distributed Control and Information System (DCIS) in Lungmen are fully integrated with the state-of-the-art computer and network technology. General Electric is the leading designer for integration of DCIS. This paper presents Network Architecture and the Site Test of DCIS. The network architectures are follows. GE NUMAC System adopts the point to point architecture, DRS System adopts Ring type architecture with SCRAMNET protocol, Inevnsys system adopts IGiga Byte Backbone mesh network with Rapid Spanning Tree Protocol, GEIS adopts Ethernet network with EGD protocol, Hitachi adopts ring type network with proprietary protocol. MHI adopt Ethernet network with UDP. The data-links are used for connection between different suppliers. The DCIS architecture supports the plant automation, the alarm prioritization and alarm suppression, and uniform MMI screen for entire plant. The Test Program regarding the integration of different network architectures and Initial DCIS architecture Setup for 161KV Energization will be discussed. Test tool for improving site test schedule, and lessons learned from FAT will be discussed too. And conclusions are at the end of this paper. (authors)

  10. Characterisation of a pneumatic muscle test station with two dynamic plants in cascade.

    Science.gov (United States)

    Serres, J L; Reynolds, D B; Phillips, C A; Rogers, D B; Repperger, D W

    2010-02-01

    Pneumatic muscle actuators (PMAs) offer significant advantages over more traditional actuators, which make them prime candidates in rehabilitation devices. A dynamic test station (DTS) is modified to demonstrate the use of a PMA for this application. The DTS includes two dynamic systems: a PMA and a DC servomotor. An overall transfer function was developed utilising characterisation data for the PMA and DC servomotor. A Tustin (bilinear) transform was performed on the overall transfer function to obtain a discrete time system. Model parameters were optimised and used to generate input voltage profiles that achieve isokinetic (constant velocity) task specifications. Percent root mean square error values (PRMSE) between the actual and ideal profiles were used to evaluate the accuracy of this method in achieving isokinetic displacement. For PMA pressures (in kPa) of 150, 350 and 550 PRMSE were 7.80, 5.40 and 2.76, respectively.

  11. SiPM application for a detector for UHE neutrinos tested at Sphinx station

    International Nuclear Information System (INIS)

    Iori, M.; Atakisi, I.O.; Chiodi, G.; Denizli, H.; Ferrarotto, F.; Kaya, M.; Yilmaz, A.; Recchia, L.; Russ, J.

    2014-01-01

    We present the preliminary test results of the prototype detector, working at Sphinx Observatory Center, Jungfraujoch (∼3800 m a.s.l.) HFSJG – Switzerland. This prototype detector is designed to measure large zenith angle showers produced by high energy neutrino interactions in the Earth crust. This station provides us an opportunity to understand if the prototype detector works safely (or not) under hard environmental conditions (the air temperature changes between −25 °C and −5 °C). The detector prototype is using silicon photomultiplier (SiPM) produced by SensL and DRS4 chip as read-out part. Measurements at different temperature at fixed bias voltage (∼29.5 V) were performed to reconstruct tracks by Time Of Flight

  12. SiPM application for a detector for UHE neutrinos tested at Sphinx station

    Science.gov (United States)

    Iori, M.; Atakisi, I. O.; Chiodi, G.; Denizli, H.; Ferrarotto, F.; Kaya, M.; Yilmaz, A.; Recchia, L.; Russ, J.

    2014-04-01

    We present the preliminary test results of the prototype detector, working at Sphinx Observatory Center, Jungfraujoch (~3800 m a.s.l.) HFSJG - Switzerland. This prototype detector is designed to measure large zenith angle showers produced by high energy neutrino interactions in the Earth crust. This station provides us an opportunity to understand if the prototype detector works safely (or not) under hard environmental conditions (the air temperature changes between -25 °C and -5 °C). The detector prototype is using silicon photomultiplier (SiPM) produced by SensL and DRS4 chip as read-out part. Measurements at different temperature at fixed bias voltage (~29.5 V) were performed to reconstruct tracks by Time Of Flight.

  13. SiPM application for a detector for UHE neutrinos tested at Sphinx station

    Energy Technology Data Exchange (ETDEWEB)

    Iori, M. [Sapienza University of Rome, Piazzale A. Moro 5, 00185 Rome (Italy); Atakisi, I.O. [University of Kafkas, 36100 Kars (Turkey); Chiodi, G. [INFN, Sezione Roma 1, Piazzale A. Moro 2, 00185 Rome (Italy); Denizli, H. [Abant Izzet Baysal University, 14280 Bolu (Turkey); Ferrarotto, F. [INFN, Sezione Roma 1, Piazzale A. Moro 2, 00185 Rome (Italy); Kaya, M. [University of Kafkas, 36100 Kars (Turkey); Yilmaz, A. [Abant Izzet Baysal University, 14280 Bolu (Turkey); Recchia, L. [INFN, Sezione Roma 1, Piazzale A. Moro 2, 00185 Rome (Italy); Russ, J. [Carnegie-Mellon University, Pittsburgh, PA 15213 (United States)

    2014-04-01

    We present the preliminary test results of the prototype detector, working at Sphinx Observatory Center, Jungfraujoch (∼3800 m a.s.l.) HFSJG – Switzerland. This prototype detector is designed to measure large zenith angle showers produced by high energy neutrino interactions in the Earth crust. This station provides us an opportunity to understand if the prototype detector works safely (or not) under hard environmental conditions (the air temperature changes between −25 °C and −5 °C). The detector prototype is using silicon photomultiplier (SiPM) produced by SensL and DRS4 chip as read-out part. Measurements at different temperature at fixed bias voltage (∼29.5 V) were performed to reconstruct tracks by Time Of Flight.

  14. The association between disease and profitability in individual finishing boars at a test station

    DEFF Research Database (Denmark)

    Jensen, Tina Birk; Baadsgaard, Niels Peter; Houe, Hans

    2008-01-01

    Endemic diseases in finisher herds are considered to be costly for the pig producer. We investigated the effect of diseases on the profit margin using data from a Danish boar test station (n = 5777) collected from July 2002 to December 2004. Boars reaching a target slaughter weight of at least 80...... kg were included in the study. Oral and parenteral treatments were used as indicator of disease in the finishing period and, pathological lesions were used as indicator of disease at slaughter. Profit margin was calculated individually for each boar as the difference between the total revenue......: profit margin. The results showed that treatment in the finishing period had a negative effect on the profit margin. According to the least square means estimates, boars that were treated parenterally had a reduction in the profit margin of 2.24 €. This corresponded to a reduction in the profit margin...

  15. Viking telecommunication effects of GEOS satellite interference based on testing at the Madrid deep space station

    Science.gov (United States)

    Stuhr, F. V.; Kent, S. S.; Galvez, J. L.; Luaces, B. G.; Pasero, G. R.; Urech, J. M.

    1976-01-01

    In support of the ongoing NASA-European Space Agency (ESA) effort to understand and control possible interference between missions, testing was conducted at the Madrid Deep Space Station from July 1975 to February 1976 to characterize the effect on Viking 1975 telecommunication link performance of Geodetic Earth-Orbiting Satellite (GEOS) downlink signals. The prime use of the data was to develop a capability to predict GEOS interference effects for evaluation of Viking 1975 mission impacts and possible temporary GEOS shutdown. Also, the data would serve as a basis for assessment of the GEOS impact on missions other than Viking as well as for more general interference applications. Performances of the reference receiver, telemetry, and planetary ranging were measured in the presence of various types of GEOS-related interference, including an unmodulated GEOS carrier and simulation of the actual spectrum by an ESA-supplied GEOS suitcase model.

  16. Modified SPC for short run test and measurement process in multi-stations

    Science.gov (United States)

    Koh, C. K.; Chin, J. F.; Kamaruddin, S.

    2018-03-01

    Due to short production runs and measurement error inherent in electronic test and measurement (T&M) processes, continuous quality monitoring through real-time statistical process control (SPC) is challenging. Industry practice allows the installation of guard band using measurement uncertainty to reduce the width of acceptance limit, as an indirect way to compensate the measurement errors. This paper presents a new SPC model combining modified guard band and control charts (\\bar{\\text{Z}} chart and W chart) for short runs in T&M process in multi-stations. The proposed model standardizes the observed value with measurement target (T) and rationed measurement uncertainty (U). S-factor (S f) is introduced to the control limits to improve the sensitivity in detecting small shifts. The model was embedded in automated quality control system and verified with a case study in real industry.

  17. Pn seismic wave travel time at the Semipalatinsk Test Site - Borovoe seismic station trace

    International Nuclear Information System (INIS)

    An, V.A.; Kaazik, P.B.; Ovchinnikov, V.M.

    2001-01-01

    This paper preparation involved 160 explosions at the Degelen Site conducted in 1961-1989 and 89 explosions at the Balapan Site conducted in 1968-1989. Pn wave travel time was tied to the sea level in accordance with velocity characteristics of the explosion hypocenter medium; and to average epicentral distance for every site basing on their local travel time curves of Pn wave relative to Borovoe station. Maximum amplitude of mean-year travel times variations is 0.3-0.5 s as at the Nevada Test Site - Borovoe trace and Mirniy (Antarctica). However, the linear trend in contrast to previous traces has negative sign (0.08 s for Degelen and 0.1 s for Balapan). Thus, Pn wave velocity increases with calendar time. (author)

  18. Space-Based Reconfigurable Software Defined Radio Test Bed Aboard International Space Station

    Science.gov (United States)

    Reinhart, Richard C.; Lux, James P.

    2014-01-01

    The National Aeronautical and Space Administration (NASA) recently launched a new software defined radio research test bed to the International Space Station. The test bed, sponsored by the Space Communications and Navigation (SCaN) Office within NASA is referred to as the SCaN Testbed. The SCaN Testbed is a highly capable communications system, composed of three software defined radios, integrated into a flight system, and mounted to the truss of the International Space Station. Software defined radios offer the future promise of in-flight reconfigurability, autonomy, and eventually cognitive operation. The adoption of software defined radios offers space missions a new way to develop and operate space transceivers for communications and navigation. Reconfigurable or software defined radios with communications and navigation functions implemented in software or VHDL (Very High Speed Hardware Description Language) provide the capability to change the functionality of the radio during development or after launch. The ability to change the operating characteristics of a radio through software once deployed to space offers the flexibility to adapt to new science opportunities, recover from anomalies within the science payload or communication system, and potentially reduce development cost and risk by adapting generic space platforms to meet specific mission requirements. The software defined radios on the SCaN Testbed are each compliant to NASA's Space Telecommunications Radio System (STRS) Architecture. The STRS Architecture is an open, non-proprietary architecture that defines interfaces for the connections between radio components. It provides an operating environment to abstract the communication waveform application from the underlying platform specific hardware such as digital-to-analog converters, analog-to-digital converters, oscillators, RF attenuators, automatic gain control circuits, FPGAs, general-purpose processors, etc. and the interconnections among

  19. The SOS-LUX-LAC-FLUORO-Toxicity-test on the International Space Station (ISS).

    Science.gov (United States)

    Rabbow, E; Rettberg, P; Baumstark-Khan, C; Horneck, G

    2003-01-01

    In the 21st century, an increasing number of astronauts will visit the International Space Station (ISS) for prolonged times. Therefore it is of utmost importance to provide necessary basic knowledge concerning risks to their health and their ability to work on the station and during extravehicular activities (EVA) in free space. It is the aim of one experiment of the German project TRIPLE-LUX (to be flown on the ISS) to provide an estimation of health risk resulting from exposure of the astronauts to the radiation in space inside the station as well as during extravehicular activities on one hand, and of exposure of astronauts to unavoidable or as yet unknown ISS-environmental genotoxic substances on the other. The project will (i) provide increased knowledge of the biological action of space radiation and enzymatic repair of DNA damage, (ii) uncover cellular mechanisms of synergistic interaction of microgravity and space radiation and (iii) examine the space craft milieu with highly specific biosensors. For these investigations, the bacterial biosensor SOS-LUX-LAC-FLUORO-Toxicity-test will be used, combining the SOS-LUX-Test invented at DLR Germany (Patent) with the commercially available LAC-FLUORO-Test. The SOS-LUX-Test comprises genetically modified bacteria transformed with the pBR322-derived plasmid pPLS-1. This plasmid carries the promoterless lux operon of Photobacterium leiognathi as a reporter element under control of the DNA-damage dependent SOS promoter of ColD as sensor element. This system reacts to radiation and other agents that induce DNA damages with a dose dependent measurable emission of bioluminescence of the transformed bacteria. The analogous LAC-FLUORO-Test has been developed for the detection of cellular responses to cytotoxins. It is based on the constitutive expression of green fluorescent protein (GFP) mediated by the bacterial protein expression vector pGFPuv (Clontech, Palo Alto, USA). In response to cytotoxic agents, this system

  20. Experiences for construction and preoperation test of Shimane nuclear power station

    International Nuclear Information System (INIS)

    Niki, Yoshiya; Taniguchi, Takashi.

    1975-01-01

    Shimane nuclear power station of Chugoku Electric Power Company has begun its commercial operation on March 29, 1974 after the construction period of 49.5 months. The fundamental construction process which Chugoku Electric Power Company and Hitachi Ltd. had agreed was 45 month process, which was the readjustment of the construction process which General Electric Company had presented for preceding nuclear power plants in Japan and its results. The achieved construction and test process required 49.5 months with 4.5 months delay. This delay occurred in two points. The one was caused by the ''upside down'' problem of control rods which had been imported from G.E. The another was caused by the restriction of the rate of load increasing. Fuel charging which indicates the substantial finish of construction works, had begun at May 1, 1973 on schedule. Therefore it can be said that the construction works had been carried out just according to the fundamental process. However, analyzing the result of progress, the pressure test of a reactor containment vessel and the set-up and the first pressure test of a reactor pressure vessel led the schedule by about 2 months. On the contrary, the subsequent works delayed by just that leading time. (Tai, I.)

  1. On test results of the superconducting magnetic energy storage (SMES) system in Ariuragawa Power Station

    International Nuclear Information System (INIS)

    Katahira, Osamu; Fukui, Fumihiko; Karano, Koichi; Irie, Fujio; Takeo, Masakatsu; Okada, Hidehiko; Shimojo, Toshikazu.

    1991-01-01

    SMES system is that for storing electric energy in the form of magnetic energy by flowing DC current through a superconducting coil by utilizing the characteristics of its superconductivity. It comprises a superconducting coil for storing energy, an AC-DC converter, the cooling system for maintaining extremely low temperature and so on. The features of SMES are the high efficiency of storing electric energy (more than 90 % in the large scale system), the fast response to store and release electric power, and effective power and reactive power can be independently and arbitrarily controlled. It is expected that SMES can be applied to the stabilization of electric power system, the adjustment of system voltage, the adjustment of varying load and so on. In order to verify the results of the laboratory research in actual power system, the system test was carried out in Ariuragawa Power Station on November 20-22, 1990. The outline of the test, the method of controlling SMES, the test results and the examination of the results are reported. (K.I.)

  2. Microbiological Tests Performed During the Design of the International Space Station ECLSS: Part 1, Bulk Phase Water and Wastewater

    Science.gov (United States)

    Roman, Monsi C.; Mittelman, Marc W.

    2010-01-01

    This slide presentation summarizes the studies performed to assess the bulk phase microbial community during the Space Station Water Recover Tests (WRT) from 1990-1998. These tests show that it is possible to recycle water from different sources including urine, and produce water that can exceed the quality of municpally produced tap water.

  3. In situ testing of the Shippingport Atomic Power Station electrical circuits

    International Nuclear Information System (INIS)

    Dinsel, M.R.; Donaldson, M.R.; Soberano, F.T.

    1987-04-01

    This report discusses the results of electrical in situ testing of selected circuits and components at the Shippingport Atomic Power Station in Shippingport, Pennsylvania. Testing was performed by EG and G Idaho in support of the United States Nuclear Regulatory Commission (USNRC) Nuclear Plant Aging Research (NPAR) Program. The goal was to determine the extent of aging or degradation of various circuits from the original plant, and the two major coreplant upgrades (representing three distinct age groups), as well as to evaluate previously developed surveillance technology. The electrical testing was performed using the Electrical Circuit Characterization and Diagnostic (ECCAD) system developed by EG and G for the US Department of Energy to use at TMI-2. Testing included measurements of voltage, effective series capacitance, effective series inductance, impedance, effective series resistance, dc resistance, insulation resistance and time domain reflectometry (TDR) parameters. The circuits evaluated included pressurizer heaters, control rod position indicator cables, miscellaneous primary system Resistance Temperature Detectors (RTDs), nuclear instrumentation cables, and safety injection system motor operated valves. It is to be noted that the operability of these circuits was tested after several years had elapsed because plant operations had concluded at Shippingport. There was no need following plant shutdown to retain the circuits in working condition, so no effort was expended for that purpose. The in situ measurements and analysis of the data confirmed the effectiveness of the ECCAD system for detecting degradation of circuit connections and splices because of high resistance paths, with most of the problems caused by corrosion. Results indicate a correlation between the chronological age of circuits and circuit degradation

  4. Electrophysiology in visually impaired children

    NARCIS (Netherlands)

    Genderen, Maria Michielde van

    2006-01-01

    Inherited retinal disorders and posterior visual pathway abnormalities are important causes of visual impairment in children. Visual electrophysiology often is indispensable in diagnosing these conditions. This thesis shows the wide range of use of pediatric electro-ophthalmology, and demonstrates

  5. Addressing Challenges to the Design & Test of Operational Lighting Environments for the International Space Station

    Science.gov (United States)

    Clark, Toni A.

    2014-01-01

    In our day to day lives, the availability of light, with which to see our environment, is often taken for granted. The designers of land based lighting systems use sunlight and artificial light as their toolset. The availability of power, quantity of light sources, and variety of design options are often unlimited. The accessibility of most land based lighting systems makes it easy for the architect and engineer to verify and validate their design ideas. Failures with an implementation, while sometimes costly, can easily be addressed by renovation. Consider now, an architectural facility orbiting in space, 260 miles above the surface of the earth. This human rated architectural facility, the International Space Station (ISS) must maintain operations every day, including life support and appropriate human comforts without fail. The facility must also handle logistics of regular shipments of cargo, including new passengers. The ISS requires accommodations necessary for human control of machine systems. Additionally, the ISS is a research facility and supports investigations performed inside and outside its livable volume. Finally, the facility must support remote operations and observations by ground controllers. All of these architectural needs require a functional, safe, and even an aesthetic lighting environment. At Johnson Space Center, our Habitability and Human Factors team assists our diverse customers with their lighting environment challenges, via physical test and computer based analysis. Because of the complexity of ISS operational environment, our team has learned and developed processes that help ISS operate safely. Because of the dynamic exterior lighting environment, uses computational modeling to predict the lighting environment. The ISS' orbit exposes it to a sunrise every 90 minutes, causing work surfaces to quickly change from direct sunlight to earthshine to total darkness. Proper planning of vehicle approaches, robotics operations, and crewed

  6. Nickel-Hydrogen Battery Cell Life Test Program Update for the International Space Station

    Science.gov (United States)

    Miller, Thomas B.

    2000-01-01

    NASA and Boeing North America are responsible for constructing the electrical power system for the International Space Station (ISS), which circles the Earth every 90 minutes in a low Earth orbit (LEO). For approximately 55 minutes of this orbit, the ISS is in sunlight, and for the remaining 35 minutes, the ISS is in the Earth s shadow (eclipse). The electrical power system must not only provide power during the sunlight portion by means of the solar arrays, but also store energy for use during the eclipse. Nickel-hydrogen (Ni/H2) battery cells were selected as the energy storage systems for ISS. Each battery Orbital Replacement Unit (ORU) comprises 38 individual series-connected Ni/H2 battery cells, and there are 48 battery ORU s on the ISS. On the basis of a limited Ni/H2 LEO data base on life and performance characteristics, the NASA Glenn Research Center at Lewis Field commenced testing through two test programs: one in-house and one at the Naval Surface Warfare Center in Crane, Indiana.

  7. The Need and Opportunity for an Integrated Research, Development and Testing Station in the Alaskan High Arctic

    Science.gov (United States)

    Hardesty, J. O.; Ivey, M.; Helsel, F.; Dexheimer, D.; Cahill, C. F.; Bendure, A.; Lucero, D. A.; Roesler, E. L.

    2016-12-01

    This presentation will make the case for development of a permanent integrated research and testing station at Oliktok Point, Alaska; taking advantage of existing assets and infrastructure, controlled airspace, an active UAS program and local partnerships. Arctic research stations provide critical monitoring and research on climate change for conditions and trends in the Arctic. The US Chair of the Arctic Council has increased awareness of gaps in our understanding of Artic systems, scarce monitoring, lack of infrastructure and readiness for emergency response. Less sea ice brings competition for commercial shipping and resource extraction. Search and rescue, pollution mitigation and safe navigation need real-time, wide-area monitoring to respond to events. Multi-national responses for international traffic will drive a greater security presence to protect citizens and sovereign interests. To address research and technology gaps, there is a national need for a High Arctic Station with an approach that partners stakeholders from science, safety and security to develop comprehensive solutions. The Station should offer year-round use, logistic support and access to varied ecological settings; phased adaptation to changing needs; and support testing of technologies such as multiple autonomous platforms, renewable energies and microgrids, and sensors in Arctic settings. We propose an Arctic Station at Oliktok Point, Alaska. Combined with the Toolik Field Station and Barrow Environmental Observatory, they form a US network of Arctic Stations. An Oliktok Point Station can provide complementary and unique assets that include: ocean access, and coastal and terrestrial systems; road access; controlled airspaces on land and ocean; nearby air facilities, medical and logistic support; atmospheric observations from an adjacent ARM facility; connections to Barrow and Toolik; fiber-optic communications; University of Alaska Fairbanks UAS Test Facility partnership; and an airstrip

  8. International Space Station (ISS) Bacterial Filter Elements (BFEs): Filter Efficiency and Pressure Testing of Returned Units

    Science.gov (United States)

    Green, Robert D.; Agui, Juan H.; Vijayakumar, R.

    2017-01-01

    The air revitalization system aboard the International Space Station (ISS) provides the vital function of maintaining a clean cabin environment for the crew and the hardware. This becomes a serious challenge in pressurized space compartments since no outside air ventilation is possible, and a larger particulate load is imposed on the filtration system due to lack of sedimentation due to the microgravity environment in Low Earth Orbit (LEO). The ISS Environmental Control and Life Support (ECLS) system architecture in the U.S. Segment uses a distributed particulate filtration approach consisting of traditional High-Efficiency Particulate Adsorption (HEPA) media filters deployed at multiple locations in each U.S. Segment module; these filters are referred to as Bacterial Filter Elements, or BFEs. These filters see a replacement interval, as part of maintenance, of 2-5 years dependent on location in the ISS. In this work, we present particulate removal efficiency, pressure drop, and leak test results for a sample set of 8 BFEs returned from the ISS after filter replacement. The results can potentially be utilized by the ISS Program to ascertain whether the present replacement interval can be maintained or extended to balance the on-ground filter inventory with extension of the lifetime of ISS beyond 2024. These results can also provide meaningful guidance for particulate filter designs under consideration for future deep space exploration missions.

  9. The Consistency Between Clinical and Electrophysiological Diagnoses

    Directory of Open Access Journals (Sweden)

    Esra E. Okuyucu

    2009-09-01

    Full Text Available OBJECTIVE: The aim of this study was to provide information concerning the impact of electrophysiological tests in the clinical management and diagnosis of patients, and to evaluate the consistency between referring clinical diagnoses and electrophysiological diagnoses. METHODS: The study included 957 patients referred to the electroneuromyography (ENMG laboratory from different clinics with different clinical diagnoses in 2008. Demographic data, referring clinical diagnoses, the clinics where the requests wanted, and diagnoses after ENMG testing were recorded and statistically evaluated. RESULTS: In all, 957 patients [644 (67.3% female and 313 (32.7% male] were included in the study. Mean age of the patients was 45.40 ± 14.54 years. ENMG requests were made by different specialists; 578 (60.4% patients were referred by neurologists, 122 (12.8% by orthopedics, 140 (14.6% by neurosurgeons, and 117 (12.2% by physical treatment and rehabilitation departments. According to the results of ENMG testing, 513 (53.6% patients’ referrals were related to their referral diagnosis, whereas 397 (41.5% patients had normal ENMG test results, and 47 (4.9% patients had a diagnosis that differed from the referring diagnosis. Among the relation between the referral diagnosis and electrophysiological diagnosis according to the clinics where the requests were made, there was no statistical difference (p= 0.794, but there were statistically significant differences between the support of different clinical diagnoses, such as carpal tunnel syndrome, polyneuropathy, radiculopathy-plexopathy, entrapment neuropathy, and myopathy based on ENMG test results (p< 0.001. CONCLUSION: ENMG is a frequently used neurological examination. As such, referrals for ENMG can be made to either support the referring diagnosis or to exclude other diagnoses. This may explain the inconsistency between clinical referring diagnoses and diagnoses following ENMG

  10. Design, modeling and testing of the Askaryan Radio Array South Pole autonomous renewable power stations

    Energy Technology Data Exchange (ETDEWEB)

    Besson, D.Z., E-mail: zedlam@ku.edu [Department of Physics and Astronomy, University of Kansas, 1082 Malott Hall, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582 (United States); Moscow Engineering and Physics Institute, 31 Kashirskaya Highway, Moscow 115409 (Russian Federation); Kennedy, D.M., E-mail: dmkennedy@ku.edu [Department of Physics and Astronomy, University of Kansas, 1082 Malott Hall, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582 (United States); Ratzlaff, K., E-mail: ratzlaff@ku.edu [Instrumentation Design Laboratory, University of Kansas, 6042 Malott Hall, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582 (United States); Young, R., E-mail: rwyoung@ku.edu [Instrumentation Design Laboratory, University of Kansas, 6042 Malott Hall, 1251 Wescoe Hall Drive, Lawrence, KS 66045-7582 (United States)

    2014-11-01

    We describe the design, construction and operation of the Askaryan Radio Array (ARA) Autonomous Renewable Power Stations, initially installed at the South Pole in December, 2010 with the goal of providing an independently operating 100 W power source capable of year-round operation in extreme environments. In addition to particle astrophysics applications at the South Pole, such a station can easily be, and has since been, extended to operation elsewhere, as described herein.

  11. Design, modeling and testing of the Askaryan Radio Array South Pole autonomous renewable power stations

    International Nuclear Information System (INIS)

    Besson, D.Z.; Kennedy, D.M.; Ratzlaff, K.; Young, R.

    2014-01-01

    We describe the design, construction and operation of the Askaryan Radio Array (ARA) Autonomous Renewable Power Stations, initially installed at the South Pole in December, 2010 with the goal of providing an independently operating 100 W power source capable of year-round operation in extreme environments. In addition to particle astrophysics applications at the South Pole, such a station can easily be, and has since been, extended to operation elsewhere, as described herein

  12. Type test of Class 1E electric cables, field splices, and connections for nuclear power generating stations - 1975

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    This Standard provides direction for establishing type tests which may be used in qualifying Class 1E electric cables, field splices, and other connections for service in nuclear power generating stations. General guidelines for qualifications are given in IEEE Std 323-1974, Standard for Qualifying Class 1E Electric Equipment for Nuclear Power Generating Stations. Categories of cables covered are those used for power control and instrumentation services. Though intended primarily to pertain to cable for field installation, this guide may also be used for the qualification of internal wiring of manufactured devices

  13. A Cryogenic Test Station for the Pre-series 2400 W @ 1.8 K Refrigeration Units for the LHC

    CERN Document Server

    Claudet, S; Gully, P; Jäger, B; Millet, F; Roussel, P; Tavian, L

    2002-01-01

    The cooling capacity below 2 K for the superconducting magnets in the Large Hadron Collider (LHC), at CERN, will be provided by eight refrigeration units at 1.8 K, each of them coupled to a 4.5 K refrigerator. The supply of the series units is linked to successful testing and acceptance of the pre-series delivered by the two selected vendors. To properly assess the performance of specific components such as cold compressors and some process specificities a dedicated test station is necessary. The test station is able to process up to 130 g/s between 4.5 & 20 K and aims at simulating the steady and transient operational modes foreseen for the LHC. After recalling the basic characteristics of the 1.8 K refrigeration units and the content of the acceptance tests of the pre-series, the principle of the test cryostat is detailed. The components of the test station and corresponding layout are described. The first testing experience is presented as well as preliminary results of the pre-series units.

  14. IEEE standard for type test of class 1E electric cables, field splices, and connections for nuclear power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1974-01-01

    The Institute of Electrical and Electronics Engineers has generated this document to provide guidance for developing a program to type test cables, field splices, and connections and obtain specific type test data. It supplements IEEE Std 323-1974 Standard for Qualifying Class IE Equipment for Nuclear Power Generating Stations, which describes basic requirements for equipment qualification. It is the integrated performance of the structures, fluid systems, the electrical systems, the instrumentation systems of the station, and in particular, the plant protection system, that limits the consequences of accidents. Seismic effects on installed cable systems are not within the scope of this document. Section 2 of this guide is an example of type tests. It is the purpose of this guide to deal with cable and connections; however, at the time of issue, detailed examples of tests for connections were not available

  15. Pelvic floor electrophysiology in spinal cord injury.

    Science.gov (United States)

    Tankisi, H; Pugdahl, K; Rasmussen, M M; Clemmensen, D; Rawashdeh, Y F; Christensen, P; Krogh, K; Fuglsang-Frederiksen, A

    2016-05-01

    The study aimed to investigate sacral peripheral nerve function and continuity of pudendal nerve in patients with chronic spinal cord injury (SCI) using pelvic floor electrophysiological tests. Twelve patients with low cervical or thoracic SCI were prospectively included. Quantitative external anal sphincter (EAS) muscle electromyography (EMG), pudendal nerve terminal motor latency (PNTML) testing, bulbocavernosus reflex (BCR) testing and pudendal short-latency somatosensory-evoked potential (SEP) measurement were performed. In EAS muscle EMG, two patients had abnormal increased spontaneous activity and seven prolonged motor unit potential duration. PNTML was normal in 10 patients. BCR was present with normal latency in 11 patients and with prolonged latency in one. The second component of BCR could be recorded in four patients. SEPs showed absent cortical responses in 11 patients and normal latency in one. Pudendal nerve and sacral lower motor neuron involvement are significantly associated with chronic SCI, most prominently in EAS muscle EMG. The frequent finding of normal PNTML latencies supports earlier concerns on the utility of this test; however, BCR and pudendal SEPs may have clinical relevance. As intact peripheral nerves including pudendal nerve are essential for efficient supportive therapies, pelvic floor electrophysiological testing prior to these interventions is highly recommended. Copyright © 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

  16. Noise test system of rotating machinery in nuclear power station based on microphone array

    Science.gov (United States)

    Chang, Xincai; Guan, Jishi; Qi, Liangcai

    2017-12-01

    Rotating machinery plays an important role in all walks of life. Once the equipment fails, equipment maintenance and shutdown will cause great social harm and economic losses. Equipment safety operations at nuclear power stations have always been of top priority. It is prone to noise when the equipment is out of order or aging. Failure to find or develop equipment at the initial stage of equipment failure or ageing will pose a serious threat to the safety of the plant’s equipment. In this paper, sound imaging diagnosis technology is applied as a supplementary method to the condition monitoring and diagnosis system of rotating machinery in nuclear power stations. It provides a powerful guarantee for the condition monitoring and fault diagnosis of rotating machinery in nuclear power stations.

  17. [Automated processing of electrophysiologic signals].

    Science.gov (United States)

    Korenevskiĭ, N A; Gubanov, V V

    1995-01-01

    The paper outlines a diagram of a multichannel analyzer of electrophysiological signals while are significantly non-stationary (such as those of electroencephalograms, myograms, etc.), by using a method based on the ranging procedure by the change-over points which may be the points of infection, impaired locality, minima, maxima, discontinuity, etc.

  18. Performance Testing of Massive MIMO Base Station with Multi-Probe Anechoic Chamber Setups

    DEFF Research Database (Denmark)

    Zhang, Fengchun; Fan, Wei; Ji, Yilin

    2018-01-01

    The utilization of massive multiple-input multipleoutput (MIMO) antenna arrays at the base station (BS) side has been identified as an enabling technique for 5G communication systems. To evaluate the true end-to-end performance of BS's, an over-the-air (OTA) radiated method is required...

  19. The development of test beds to support the definition and evolution of the Space Station Freedom power system

    Science.gov (United States)

    Soeder, James F.; Frye, Robert J.; Phillips, Rudy L.

    1991-01-01

    Since the beginning of the Space Station Freedom Program (SSFP), the NASA Lewis Research Center (LeRC) and the Rocketdyne Division of Rockwell International have had extensive efforts underway to develop testbeds to support the definition of the detailed electrical power system design. Because of the extensive redirections that have taken place in the Space Station Freedom Program in the past several years, the test bed effort was forced to accommodate a large number of changes. A short history of these program changes and their impact on the LeRC test beds is presented to understand how the current test bed configuration has evolved. The current test objectives and the development approach for the current DC test bed are discussed. A description of the test bed configuration, along with its power and controller hardware and its software components, is presented. Next, the uses of the test bed during the mature design and verification phase of SSFP are examined. Finally, the uses of the test bed in the operation and evolution of the SSF are addressed.

  20. International Space Station Environmental Control and Life Support System Acceptance Testing for Node 1 Temperature and Humidity Control Subsystem

    Science.gov (United States)

    Williams, David E.

    2011-01-01

    The International Space Station (ISS) Node 1 Environmental Control and Life Support (ECLS) System is comprised of five subsystems: Atmosphere Control and Storage (ACS), Atmosphere Revitalization (AR), Fire Detection and Suppression (FDS), Temperature and Humidity Control (THC), and Water Recovery and Management (WRM). This paper will provide a summary of the Node 1 ECLS THC subsystem design and a detailed discussion of the ISS ECLS Acceptance Testing methodology utilized for this subsystem.The International Space Station (ISS) Node 1 Environmental Control and Life Support (ECLS) System is comprised of five subsystems: Atmosphere Control and Storage (ACS), Atmosphere Revitalization (AR), Fire Detection and Suppression (FDS), Temperature and Humidity Control (THC), and Water Recovery and Management (WRM). This paper will provide a summary of the Node 1 ECLS THC subsystem design and a detailed discussion of the ISS ECLS Acceptance Testing methodology utilized for this subsystem.

  1. The assessment of visually impaired persons working capacities using electrophysiological and ophthalmic ergonomics methods

    Directory of Open Access Journals (Sweden)

    M. I. Razumovsky

    2014-07-01

    Full Text Available Aim was to analyze working capacities of visually impaired persons by means of complex electrophysiological and ophthalmic ergonomics eye examination.Materials and methods. Standard clinical ophthalmologic examination (visual acuity measurement, refractometry, biomicroscopy, ophthalmoscopy as well as electrophysiological (electrooculography, electrical sensitivity of the eye, critical flicker fusion frequency and ophthalmic ergonomics tests (accommodation measurement, professional testing using automated system «Proftest-1» were performed.Results. Complex electrophysiological and ophthalmic ergonomics tests were performed in 20 visually impaired persons. Their results revealed direct correlation between electrophysiological and ophthalmic ergonomics indices.Conclusion. Working capacities of visually impaired persons can be assessed reliably using complex electrophysiological and ophthalmic ergonomics eye examination only.

  2. The assessment of visually impaired persons working capacities using electrophysiological and ophthalmic ergonomics methods

    Directory of Open Access Journals (Sweden)

    M. I. Razumovsky

    2014-01-01

    Full Text Available Aim was to analyze working capacities of visually impaired persons by means of complex electrophysiological and ophthalmic ergonomics eye examination.Materials and methods. Standard clinical ophthalmologic examination (visual acuity measurement, refractometry, biomicroscopy, ophthalmoscopy as well as electrophysiological (electrooculography, electrical sensitivity of the eye, critical flicker fusion frequency and ophthalmic ergonomics tests (accommodation measurement, professional testing using automated system «Proftest-1» were performed.Results. Complex electrophysiological and ophthalmic ergonomics tests were performed in 20 visually impaired persons. Their results revealed direct correlation between electrophysiological and ophthalmic ergonomics indices.Conclusion. Working capacities of visually impaired persons can be assessed reliably using complex electrophysiological and ophthalmic ergonomics eye examination only.

  3. International Space Station Environmental Control and Life Support System Acceptance Testing for Node 1 Atmosphere Control and Supply Subsystem

    Science.gov (United States)

    Williams, David E.

    2009-01-01

    The International Space Station (ISS) Node 1 Environmental Control and Life Support (ECLS) System is comprised of five subsystems: Atmosphere Control and Supply (ACS), Atmosphere Revitalization (AR), Fire Detection and Suppression (FDS), Temperature and Humidity Control (THC), and Water Recovery and Management (WRM). This paper provides a summary of the Node 1 ECLS ACS subsystem design and a detailed discussion of the ISS ECLS Acceptance Testing methodology utilized for that subsystem.

  4. Investigation of accident management procedures related to loss of feedwater and station blackout in PSB-VVER integral test facility

    Energy Technology Data Exchange (ETDEWEB)

    Bucalossi, A. [EC JRC, (JRC F.5) PO Box 2, 1755 ZG Petten (Netherlands); Del Nevo, A., E-mail: alessandro.delnevo@enea.it [ENEA, C.R. Brasimone, 40032 Camugnano (Italy); Moretti, F.; D' Auria, F. [GRNSPG, Universita di Pisa, via Diotisalvi 2, 56100 Pisa (Italy); Elkin, I.V.; Melikhov, O.I. [Electrogorsk Research and Engineering Centre, Electrogorsk, Moscow Region (Russian Federation)

    2012-09-15

    Highlights: Black-Right-Pointing-Pointer Four integral test facility experiments related to VVER-1000 reactor. Black-Right-Pointing-Pointer TH response of the VVER-1000 primary system following total loss of feedwater and station blackout scenarios. Black-Right-Pointing-Pointer Accident management procedures in case of total loss of feedwater and station blackout. Black-Right-Pointing-Pointer Experimental data represent an improvement of existing database for TH code validation. - Abstract: VVER 1000 reactors have some unique and specific features (e.g. large primary and secondary side fluid inventory, horizontal steam generators, core design) that require dedicated experimental and analytical analyses in order to assess the performance of safety systems and the effectiveness of possible accident management strategies. The European Commission funded project 'TACIS 2.03/97', Part A, provided valuable experimental data from the large-scale (1:300) PSB-VVER test facility, investigating accident management procedures in VVER-1000 reactor. A test matrix was developed at University of Pisa (responsible of the project) with the objective of obtaining the experimental data not covered by the OECD VVER validation matrix and with main focus on accident management procedures. Scenarios related to total loss of feed water and station blackout are investigated by means of four experiments accounting for different countermeasures, based on secondary cooling strategies and primary feed and bleed procedures. The transients are analyzed thoroughly focusing on the identification of phenomena that will challenge the code models during the simulations.

  5. Final Bioventing Pilot Test Work Plan for Base Exchange Service Station Underground Storage Tank Area, Vandenberg Air Force Base, California. Part I

    National Research Council Canada - National Science Library

    1992-01-01

    This pilot test work plan presents the scope of an in situ enhanced biological degradation, or "bioventing", pilot test for treatment of gasoline- contaminated soils at the Base Exchange Service Station (BXSS...

  6. Nonpoint Pollution Discharge Permit Testing and Control Strategies at Naval Air Station Whidbey Island.

    Science.gov (United States)

    1991-01-01

    were published in the 16 November 1990 Federal Recister in response to the Water Quality Act of 1987. The existing station permit expires in 1992 and...anaerobic decomposition potential may be of major significance. Biodegradation may not occur, however, if other factors needed for bacterial growth are not... bacterially mediated oxidation of ammonia-nitrogen, these compounds can be toxic to humans or other mammals if present at excessive levels. Sources include

  7. Field testing of a 1,300MVA turbine generator for the Oi nuclear-power station

    International Nuclear Information System (INIS)

    Inoue, Toshiaki; Tajiri, Yoshiaki; Ito, Hiroyuki; Fukuda, Mitsuo.

    1980-01-01

    The first Mitsubishi 1,300MVA turbine generator for this power station was put into commercial operation in March 1979, and the second unit in December of that year. The turbine generators use new technology in a variety of areas, including the cooling system, to achieve great increases in capacity over previously designed generators, and are destined to become the worldwide standard for large-scale generators of this type. Valuable experience was gained in the installation and testing of the generators. The outline of the tests performed on the generators with respect to heating and vibration are described in the article. (author)

  8. A 6 kW at 4.5 K helium refrigerator for CERN's Cryogenic Test Station

    International Nuclear Information System (INIS)

    Gistau, G.M.; Bonneton, M.

    1994-01-01

    For purposes of testing the present LEP superconducting resonant cavities and the future LHC magnets, CERN built a test station the cryogenic power of which is presently supplied by a dedicated 6 kW at 4.5 K helium refrigerator. The thermodynamic cycle is discussed and special emphasis is put on a new cryogenic expansion turbine operating in the liquid phase. Information is given about: the cycle screw compressors' performances, the general performance of the refrigerator, the expected efficiency enhancement due to the liquid turbine, an off-design turn down operation

  9. Development and Certification of Ultrasonic Background Noise Test (UBNT) System for use on the International Space Station (ISS)

    Science.gov (United States)

    Prosser, William H.; Madaras, Eric I.

    2011-01-01

    As a next step in the development and implementation of an on-board leak detection and localization system on the International Space Station (ISS), there is a documented need to obtain measurements of the ultrasonic background noise levels that exist within the ISS. This need is documented in the ISS Integrated Risk Management System (IRMA), Watch Item #4669. To address this, scientists and engineers from the Langley Research Center (LaRC) and the Johnson Space Center (JSC), proposed to the NASA Engineering and Safety Center (NESC) and the ISS Vehicle Office a joint assessment to develop a flight package as a Station Development Test Objective (SDTO) that would perform ultrasonic background noise measurements within the United States (US) controlled ISS structure. This document contains the results of the assessment

  10. ASME XI stroke time testing of solenoid valves at Connecticut Yankee Station

    Energy Technology Data Exchange (ETDEWEB)

    Martin, C.W.

    1996-12-01

    Connecticut Yankee Atomic Power Company has developed the capability of measuring the stroke times of AC and DC solenoid valves. This allows the station to measure the stroke time of any solenoid valve in the plant, even those valves which do not have valve stem position indicators. Connecticut Yankee has adapted the ITI MOVATS Checkmate 3 system, using a signal input from a Bruel and Kjaer (B&K) Model 4382 acoustic accelerometer and the Schaumberg Campbell Associates (SCA) Model SCA-1148 dual sensor, which is a combined accelerometer and gaussmeter.

  11. ASME XI stroke time testing of solenoid valves at Connecticut Yankee Station

    International Nuclear Information System (INIS)

    Martin, C.W.

    1996-01-01

    Connecticut Yankee Atomic Power Company has developed the capability of measuring the stroke times of AC and DC solenoid valves. This allows the station to measure the stroke time of any solenoid valve in the plant, even those valves which do not have valve stem position indicators. Connecticut Yankee has adapted the ITI MOVATS Checkmate 3 system, using a signal input from a Bruel and Kjaer (B ampersand K) Model 4382 acoustic accelerometer and the Schaumberg Campbell Associates (SCA) Model SCA-1148 dual sensor, which is a combined accelerometer and gaussmeter

  12. Materials for the field test - students' attitudes to nuclear power stations. Materialien zum Unterrichtsversuch: Kernkraftwerke in der Einstellung von Jugendlichen

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, L; Kattmann, U; Lucht, H; Spada, H [Kiel Univ. (Germany, F.R.). Inst. fuer die Paedagogik der Naturwissenschaften (IPN)

    1975-01-01

    This working paper contains all the materials developed for and used in the field test of 'Student Attitudes toward Atomic Power Stations'. This research is a component of a larger project called 'Attitudes and Attitudes Change with Regard to Problems of Energy Supply and their Consequences for our Environment'. A central aim of this project is the development of instrumental strategies enabling the student to build up in this field a critically reflective and active behavior and attitudes based on sound problem consciousness. These instrumental strategies are derived from theories of social, learning and environmental psychology. A concrete result of these efforts are the materials of the field test mentioned above. They include: a) The draft of an instructional unit 'Atomic Power Stations - Prosperity or Disaster' with - a booklet on the subject matter for students and teachers - a paper on the contents of the instructional unit and their sequence - information for the students concerning the aims of the investigation - working materials for the students - reading materials for the teachers informing them about the proposed instructional strategies based on the psychological theories: (1) model-learning and the structuring of knowledge, (2) how to activate and motivate students, (3) the stabilization of attitudes and (4) small group work. b) Instruments for testing and observation. These instruments were used within a criterion-oriented evaluation and for a test of the effects of the different proposed items used in the instruction.

  13. Low-cost extrapolation method for maximal LTE radio base station exposure estimation: test and validation.

    Science.gov (United States)

    Verloock, Leen; Joseph, Wout; Gati, Azeddine; Varsier, Nadège; Flach, Björn; Wiart, Joe; Martens, Luc

    2013-06-01

    An experimental validation of a low-cost method for extrapolation and estimation of the maximal electromagnetic-field exposure from long-term evolution (LTE) radio base station installations are presented. No knowledge on downlink band occupation or service characteristics is required for the low-cost method. The method is applicable in situ. It only requires a basic spectrum analyser with appropriate field probes without the need of expensive dedicated LTE decoders. The method is validated both in laboratory and in situ, for a single-input single-output antenna LTE system and a 2×2 multiple-input multiple-output system, with low deviations in comparison with signals measured using dedicated LTE decoders.

  14. Low-cost extrapolation method for maximal lte radio base station exposure estimation: Test and validation

    International Nuclear Information System (INIS)

    Verloock, L.; Joseph, W.; Gati, A.; Varsier, N.; Flach, B.; Wiart, J.; Martens, L.

    2013-01-01

    An experimental validation of a low-cost method for extrapolation and estimation of the maximal electromagnetic-field exposure from long-term evolution (LTE) radio base station installations are presented. No knowledge on down-link band occupation or service characteristics is required for the low-cost method. The method is applicable in situ. It only requires a basic spectrum analyser with appropriate field probes without the need of expensive dedicated LTE decoders. The method is validated both in laboratory and in situ, for a single-input single-output antenna LTE system and a 2x2 multiple-input multiple-output system, with low deviations in comparison with signals measured using dedicated LTE decoders. (authors)

  15. Summary of in-situ tests of filter systems in nuclear power stations

    International Nuclear Information System (INIS)

    Hesboel, R.; Persson, M.

    1980-04-01

    Iodine filter installations at nuclear power plants are systematically tested regarding light assembly and retention of iodine. Studsvik Energiteknik AB has collected a sizeable amount of test data over the years. The filter installations and test methods are described, followed by an analysis of test results and experience over the past 10 years. As a rule in-situ tests have been carried out at low relative humidity, in 90% of them below 50% relative humidity. Variations in flow have been larger than expected, and the variations in operative conditions affect test results. The test method is, however, regarded acceptable for off-gas filter systems. Additional test methods are required for the auxiliary and energency systems. (G.B.)

  16. Pilot tests for dismantling by blasting of the biological shield of a shut down nuclear power station

    International Nuclear Information System (INIS)

    Freund, H.U.

    1995-01-01

    Following free-field tests on concrete blocks the feasibility of explosive dismantling of the biological shield of nuclear power stations has been succesfully tested at the former hotsteam reaction in Karlstein/Main Germany. For this purpose a model shield of scale 1:2 was embedded into the reactor structure at which bore-hole blasting tests employing up to about 15 kg of explosive were performed. An elaborate measurement system allowed to receive detailed information on the blast side-effects: Special emphasis was focussed on the quantitative registration of the dynamic blast loads; data for the transfer of the dismantling method to the removal of real ractor structures were obtained. (orig.) [de

  17. Simulation of the transient behaviour of the Mulheim-Karlich nuclear power station and comparison with startup tests

    International Nuclear Information System (INIS)

    Burchhardt, W.; Weber, J.P.

    1987-01-01

    Among the startup tests of the Mulheim-Karlich nuclear power station an anticipated turbine trip and a rector trip have been performed. Calculations have been done for both tests by the authors using the computer codes DYNODE-P and ALMOD4. At a given reactor power the transient behavior of the plant is determined by the heat load of the once-through steam generators (OTSG), which in turn is governed by the integral control system. As expected the behavior of the plant after the trips can be exactly reproduced only if the bypass control system is completely modelled. In addition the heat transfer to the secondary side of the OTSG which governs the steam production has to be calculated close to reality. comparing the calculated results with the measured test data it is demonstrated that either code can be used to reproduce the transient behavior of the plant

  18. The role of a certified calibration laboratory in a station's measuring and test equipment calibration, repair, and documentation program

    International Nuclear Information System (INIS)

    Ebenstreit, K.; MacIntosh, N.

    1995-01-01

    This paper outlines the role of a Certified Calibration Laboratory in- ensuring that the requirements of Measuring and Test Equipment calibration, identification, and traceability are met and documented. The Nuclear environment is one which is subject to influences from numerous 'quality agents'. One of the fields which comes under the scrutiny of the quality agents is that of equipment calibration and repair (both field components and M and TE). There is a responsibility to produce a superior product for the Ontario Consumer. The maintenance and calibration of Station Systems and their components have a direct impact on this output. The Measuring and Test Equipment element in each of these needs can be addressed by having a defined group of Maintenance Staff to execute a Measuring and Test Equipment Program which meets specific parameters. (author)

  19. PERIPHERAL NEUROPATHY ELECTROPHYSIOLOGICAL SCREENING IN CHILDREN WITH CELIAC DISEASE

    Directory of Open Access Journals (Sweden)

    Şedat IŞIKAY

    2015-06-01

    Full Text Available Background The involvement of the peripheral nervous system in children with celiac disease is particularly rare. Objective The aim of this study was to assess the need for neurophysiological testing in celiac disease patients without neurological symptoms in order to detect early subclinical neuropathy and its possible correlations with clinical and demographic characteristics. Methods Two hundred and twenty consecutive children with celiac disease were screened for neurological symptoms and signs, and those without symptoms or signs were included. Also, patients with comorbidities associated with peripheral neuropathy or a history of neurological disease were excluded. The remaining 167 asymptomatic patients as well as 100 control cases were tested electro-physiologically for peripheral nervous system diseases. Motor nerve conduction studies, including F-waves, were performed for the median, ulnar, peroneal, and tibial nerves, and sensory nerve conduction studies were performed for the median, ulnar, and sural nerves with H reflex of the soleus muscle unilaterally. All studies were carried out using surface recording electrodes. Normative values established in our laboratory were used. Results Evidence for subclinical neuropathy was not determined with electrophysiological studies in any of the participants. Conclusion In this highly selective celiac disease group without any signs, symptoms as well as the predisposing factors for polyneuropathy, we did not determine any cases with neuropathy. With these results we can conclude that in asymptomatic cases with celiac disease electrophysiological studies are not necessary. However, larger studies with the electrophysiological studies performed at different stages of disease at follow-ups are warranted.

  20. Retinal dysfunction and refractive errors: an electrophysiological study of children

    Science.gov (United States)

    Flitcroft, D I; Adams, G G W; Robson, A G; Holder, G E

    2005-01-01

    Aims: To evaluate the relation between refractive error and electrophysiological retinal abnormalities in children referred for investigation of reduced vision. Methods: The study group comprised 123 consecutive patients referred over a 14 month period from the paediatric service of Moorfields Eye Hospital for electrophysiological investigation of reduced vision. Subjects were divided into five refractive categories according to their spectacle correction: high myopia (⩽−6D), low myopia (>−6D and ⩽−0.75D), emmetropia (>−0.75 and 1.5D) and ERG abnormalities (18/35 with high astigmatism v 20/88 without, χ2 test, p = 0.002). There was no significant variation in frequency of abnormalities between low myopes, emmetropes, and low hyperopes. The rate of abnormalities was very similar in both high myopes (8/15) and high hyperopes (5/10). Conclusions: High ametropia and astigmatism in children being investigated for poor vision are associated with a higher rate of retinal electrophysiological abnormalities. An increased rate of refractive errors in the presence of retinal pathology is consistent with the hypothesis that the retina is involved in the process of emmetropisation. Electrophysiological testing should be considered in cases of high ametropia in childhood to rule out associated retinal pathology. PMID:15774929

  1. International Space Station Lithium-Ion Main Battery Thermal Runaway Propagation Test

    Science.gov (United States)

    Dalton, Penni J.; North, Tim

    2017-01-01

    In 2010, the ISS Program began the development of Lithium-Ion (Li-Ion) batteries to replace the aging Ni-H2 batteries on the primary Electric Power System (EPS). After the Boeing 787 Li-Ion battery fires, the NASA Engineering and Safety Center (NESC) Power Technical Discipline Team was tasked by ISS to investigate the possibility of Thermal Runaway Propagation (TRP) in all Li-Ion batteries used on the ISS. As part of that investigation, NESC funded a TRP test of an ISS EPS non-flight Li-Ion battery. The test was performed at NASA White Sands Test Facility in October 2016. This paper will discuss the work leading up to the test, the design of the test article, and the test results.

  2. Electrophysiological evidence for phenomenal consciousness.

    Science.gov (United States)

    Revonsuo, Antti; Koivisto, Mika

    2010-09-01

    Abstract Recent evidence from event-related brain potentials (ERPs) lends support to two central theses in Lamme's theory. The earliest ERP correlate of visual consciousness appears over posterior visual cortex around 100-200 ms after stimulus onset. Its scalp topography and time window are consistent with recurrent processing in the visual cortex. This electrophysiological correlate of visual consciousness is mostly independent of later ERPs reflecting selective attention and working memory functions. Overall, the ERP evidence supports the view that phenomenal consciousness of a visual stimulus emerges earlier than access consciousness, and that attention and awareness are served by distinct neural processes.

  3. Construction and start-up testing experience of Kashiwazakikariwa Nuclear Power Station Unit No.1

    International Nuclear Information System (INIS)

    Natsume, Nobuo; Murakami, Hideaki

    1986-01-01

    In order to overcome the new location condition in Japan Sea coast, new techniques were developed and adopted to ensure the safety in construction and to shorten the construction period as far as possible. The commercial operation was started on September 18, 1985. This plant is a BWR plant of 1100 MWe output. The results of the improvement and standardization of BWRs and the measures for reliability improvement and radiation dose reduction were fully adopted in this plant. The site of the power station and the layout of the main facilities are explained. As the features of the location condition, the severe weather condition in winter such as snow, wind and lightning and high waves in the sea were considered. The rockbed for installing the foundation of the reactor building was deep, and the aseismatic design condition was made stricter, accordingly, the quantity of materials increased. A tent dome was developed to cover above the reactor containment vessel being assembled, a lightning forecast system was installed, and synchro-lift method was adopted for caisson breakwaters. The countermeasures to the deep rockbed and the measures to shorten the construction period were taken. The results of the trial operation are reported. (Kako, I.)

  4. Materials International Space Station Experiment (MISSE) 5 Developed to Test Advanced Solar Cell Technology Aboard the ISS

    Science.gov (United States)

    Wilt, David M.

    2004-01-01

    The testing of new technologies aboard the International Space Station (ISS) is facilitated through the use of a passive experiment container, or PEC, developed at the NASA Langley Research Center. The PEC is an aluminum suitcase approximately 2 ft square and 5 in. thick. Inside the PEC are mounted Materials International Space Station Experiment (MISSE) plates that contain the test articles. The PEC is carried to the ISS aboard the space shuttle or a Russian resupply vehicle, where astronauts attach it to a handrail on the outer surface of the ISS and deploy the PEC, which is to say the suitcase is opened 180 deg. Typically, the PEC is left in this position for approximately 1 year, at which point astronauts close the PEC and it is returned to Earth. In the past, the PECs have contained passive experiments, principally designed to characterize the durability of materials subjected to the ultraviolet radiation and atomic oxygen present at the ISS orbit. The MISSE5 experiment is intended to characterize state-of-art (SOA) and beyond photovoltaic technologies.

  5. Study of the mechanical properties of the electric power station components: the punch test

    International Nuclear Information System (INIS)

    Isselin, J.

    2003-03-01

    The aging of the electric production park implies an increasing need of knowledge concerning the evolution of the mechanical properties of its components. With regard to this problem, the availability in material is more and more small. This work proposes to characterize these properties through a mechanical test called Punch test. The main characteristic of this test is to use very small volume samples. The development of this test has been carried out by the study of a 15 MDV 4-05 steel coming from a steam drum of a thermal power plant after 145000 hours of service. At first, we have measured the influence of the parameters of this test. Then, the study has dealt more particularly on the transition temperature of the material. With the finite element simulation method, the strain hardening coefficient of the material has been determined. (O.M.)

  6. Tests of Shaft Seal Systems of Circulation Pumps during Station Blackout

    Energy Technology Data Exchange (ETDEWEB)

    Beisiegel, A.; Foppe, F.; Wich, M.

    2014-07-01

    AREVA GmbH operates a unique Thermal-hydraulic plat form in Germany, France and USA. It is recognised as a test body according to ISO 17025. The Deutsche Akkreditierungsstelle GmbH (DAkkS - German Society for Accreditation) has also certified the Thermal-hydraulic platform as an independent inspection body Type C according to ISO 17020. A part of this platform is the Component Laboratory located in Karlstein, Germany which is in operation since more than 50 years. The testing activities cover a wide range as: Critical Heat Flux Tests, Valve Testing and Environmental Qualification for safety related components. Since 2011 the Component Qualification Karlstein extended their testing scope for different types of Shaft Seal Systems. (Author)

  7. Testing the reliability of supply pipings of the pump-fed power station Markersbach

    Energy Technology Data Exchange (ETDEWEB)

    Radtke, W; Perout, A; Hellwig, K

    1981-01-01

    The leakage tests for the pressurised part of steam raising units is carried out during erection of steam raising units by halogen leak indicators. The effect which is produced by spontaneous change of alkali emission of a glowing anode if it comes into contact with molecules containing halogens is used. The erection leak detection equipment which is independent of the mains supply, works on the principle of high voltage corona discharge. Other equipment is also described briefly. All the equipment described uses dichlorfluormethane (CF/sub 2/Cl/sub 2/) as the halogen test gas - with the commercial name Fridohna 12. The test pressure in the pressurised part of the steam raising unit is 0.5 MPa and the mixing ratio of Fridohna 12 to compressed air is 0.12 kg of Fridohna 12 to 1 cubic metre of atmospheric air. The halogen leak test is superior to the water pressure test.

  8. Early electrophysiological findings in Fisher-Bickerstaff syndrome.

    Science.gov (United States)

    Alberti, M A; Povedano, M; Montero, J; Casasnovas, C

    2017-09-06

    The term Fisher-Bickerstaff syndrome (FBS) has been proposed to describe the clinical spectrum encompassing Miller-Fisher syndrome (MFS) and Bickerstaff brainstem encephalitis. The pathophysiology of FBS and the nature of the underlying neuropathy (demyelinating or axonal) are still subject to debate. This study describes the main findings of an early neurophysiological study on 12 patients diagnosed with FBS. Retrospective evaluation of clinical characteristics and electrophysiological findings of 12 patients with FBS seen in our neurology department within 10 days of disease onset. Follow-up electrophysiological studies were also evaluated, where available. The most frequent electrophysiological finding, present in 5 (42%) patients, was reduced sensory nerve action potential (SNAP) amplitude in one or more nerves. Abnormalities were rarely found in motor neurography, with no signs of demyelination. The cranial nerve exam revealed abnormalities in 3 patients (facial neurography and/or blink reflex test). Three patients showed resolution of SNAP amplitude reduction in serial neurophysiological studies, suggesting the presence of reversible sensory nerve conduction block. Results from cranial MRI scans were normal in all patients. An electrophysiological pattern of sensory axonal neuropathy, with no associated signs of demyelination, is an early finding of FBS. Early neurophysiological evaluation and follow-up are essential for diagnosing patients with FBS. Copyright © 2017 Sociedad Española de Neurología. Publicado por Elsevier España, S.L.U. All rights reserved.

  9. A highly versatile and easily configurable system for plant electrophysiology.

    Science.gov (United States)

    Gunsé, Benet; Poschenrieder, Charlotte; Rankl, Simone; Schröeder, Peter; Rodrigo-Moreno, Ana; Barceló, Juan

    2016-01-01

    In this study we present a highly versatile and easily configurable system for measuring plant electrophysiological parameters and ionic flow rates, connected to a computer-controlled highly accurate positioning device. The modular software used allows easy customizable configurations for the measurement of electrophysiological parameters. Both the operational tests and the experiments already performed have been fully successful and rendered a low noise and highly stable signal. Assembly, programming and configuration examples are discussed. The system is a powerful technique that not only gives precise measuring of plant electrophysiological status, but also allows easy development of ad hoc configurations that are not constrained to plant studies. •We developed a highly modular system for electrophysiology measurements that can be used either in organs or cells and performs either steady or dynamic intra- and extracellular measurements that takes advantage of the easiness of visual object-oriented programming.•High precision accuracy in data acquisition under electrical noisy environments that allows it to run even in a laboratory close to electrical equipment that produce electrical noise.•The system makes an improvement of the currently used systems for monitoring and controlling high precision measurements and micromanipulation systems providing an open and customizable environment for multiple experimental needs.

  10. Extended Bioventing Testing Results at the BX Service Station Site, Patrick AFB, Florida

    National Research Council Canada - National Science Library

    Marchand, Ed

    1997-01-01

    .... Soil gas samples were collected, and in situ respiration testing was performed by Parsons ES from 8 to 14 November 1996 to assess the extent of remediation completed during approximately 3 months...

  11. Human Factors Assessment of the UH-60M Crew Station During the Limited User Test (LUT)

    National Research Council Canada - National Science Library

    Havir, Thomas J; Durbin, David B; Frederick, Lorraine J; Hicks, Jamison S

    2006-01-01

    The utility helicopter (UH)-60M Product Manager requested the U.S. Army Research Laboratory's Human Research and Engineering Directorate to participate in the Limited User Test for the UH-60M Black Hawk...

  12. Performance testing of the environmental TLD system for the Three Mile Island Nuclear Station.

    Science.gov (United States)

    Toke, L F; Carson, B H; Baker, G G; McBride, M H; Plato, P A; Miklos, J A

    1984-05-01

    Panasonic UD-801 thermoluminescent dosimeters ( TLDs ) containing two calcium sulfate phosphors were tested under Performance Specification 3.1 established by the American National Standard Institute ( ANSI75 ) and in the U.S. Nuclear Regulatory Commission's Regulatory Guide 4.13 ( NRC77 ). The specific qualifying tests included TLD uniformity, reproducibility, energy dependence and directional dependence. The overall measurement uncertainties and associated confidence levels are within the prescribed guidelines defined in the qualifying requirements for environmental TLDs .

  13. Structural integrity test of prestressed concrete containment vessel for Tsuruga Unit No. 2 Nuclear Power Station

    International Nuclear Information System (INIS)

    Tamura, S.; Nagata, K.; Takeda, T.; Yamaguchi, T.; Nakayama, T.

    1987-01-01

    In introducing the PCCV to Japan, various verification tests were carried out to understand the structural performance of the PCCV and confirm the reliability of its design. In addition to those tests, a Structural Integrity Test (SIT) was conducted in Feb. 1986 as a final acceptance test. This report discusses the results of the SIT on the PCCV. The test was carried out simultaneously with an Integrated Leak Rate Test (ILRT) under the same pressure sequence. 1) Pressure-displacement relationships and pressure-strain relationships were more or less linear. 2) The measured displacement values at the maximum pressure (4.5 kgf/cm 2 G) corresponded well with calculated values. Correspondence with converted displacement obtained from strain and measured displacement was also good. 3) The residual displacement when 24 hours had elapsed after completion of depressurization was not more than 10% of the displacement at the maximum pressure. 4) The variation in tendon force at the maximum pressure is smaller than the calculated value in proportion to the elongation of the PCCV. 5) Although fine surface cracks due to shrinkage of concrete were seen, new structural cracks due to pressure were not observed. The leakage rate was evaluated at 0.016% of volume per day. It is much smaller than the design value of 0.1% of volume per day. (orig./HP)

  14. Risk-based inservice testing program modifications at Palo Verde nuclear generating station

    Energy Technology Data Exchange (ETDEWEB)

    Knauf, S.; Lindenlaub, B.; Linthicum, R.

    1996-12-01

    Arizona Public Service Company (APS) is investigating changes to the Palo Verde Inservice Testing (IST) Program that are intended to result in the reduction of the required test frequency for various valves in the American Society of Mechanical Engineers (ASME) Section XI IST program. The analytical techniques employed to select candidate valves and to demonstrate that these frequency reductions are acceptable are risk based. The results of the Palo Verde probabilistic risk assessment (PRA), updated in June 1994, and the risk significant determination performed as part of the implementation efforts for 10 CFR 50.65 (the maintenance rule) were used to select candidate valves for extended test intervals. Additional component level evaluations were conducted by an `expert panel.` The decision to pursue these changes was facilitated by the ASME Risk-Based Inservice Testing Research Task Force for which Palo Verde is participating as a pilot plant. The NRC`s increasing acceptance of cost beneficial licensing actions and risk-based submittals also provided incentive to seek these changes. Arizona Public Service is pursuing the risk-based IST program modification in order to reduce the unnecessary regulatory burden of the IST program through qualitative and quantitative analysis consistent with maintaining a high level of plant safety. The objectives of this project at Palo Verde are as follows: (1) Apply risk-based technologies to IST components to determine their risk significance (i.e., high or low). (2) Apply a combination of deterministic and risk-based methods to determine appropriate testing requirements for IST components including improvement of testing methods and frequency intervals for high-risk significant components. (3) Apply risk-based technologies to high-risk significant components identified by the {open_quotes}expert panel{close_quotes} and outside of the IST program to determine whether additional testing requirements are appropriate.

  15. Risk-based inservice testing program modifications at Palo Verde nuclear generating station

    International Nuclear Information System (INIS)

    Knauf, S.; Lindenlaub, B.; Linthicum, R.

    1996-01-01

    Arizona Public Service Company (APS) is investigating changes to the Palo Verde Inservice Testing (IST) Program that are intended to result in the reduction of the required test frequency for various valves in the American Society of Mechanical Engineers (ASME) Section XI IST program. The analytical techniques employed to select candidate valves and to demonstrate that these frequency reductions are acceptable are risk based. The results of the Palo Verde probabilistic risk assessment (PRA), updated in June 1994, and the risk significant determination performed as part of the implementation efforts for 10 CFR 50.65 (the maintenance rule) were used to select candidate valves for extended test intervals. Additional component level evaluations were conducted by an 'expert panel.' The decision to pursue these changes was facilitated by the ASME Risk-Based Inservice Testing Research Task Force for which Palo Verde is participating as a pilot plant. The NRC's increasing acceptance of cost beneficial licensing actions and risk-based submittals also provided incentive to seek these changes. Arizona Public Service is pursuing the risk-based IST program modification in order to reduce the unnecessary regulatory burden of the IST program through qualitative and quantitative analysis consistent with maintaining a high level of plant safety. The objectives of this project at Palo Verde are as follows: (1) Apply risk-based technologies to IST components to determine their risk significance (i.e., high or low). (2) Apply a combination of deterministic and risk-based methods to determine appropriate testing requirements for IST components including improvement of testing methods and frequency intervals for high-risk significant components. (3) Apply risk-based technologies to high-risk significant components identified by the open-quotes expert panelclose quotes and outside of the IST program to determine whether additional testing requirements are appropriate

  16. IEEE guide for planning of pre-operational testing programs for class 1E power systems for nuclear-power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    The Institute of Electrical and Electronics Engineers (IEEE) guide for pre-operational testing of Class 1E power systems for nuclear-power generating stations is presented. The guidelines apply to power systems both ac and dc supplies but not to the equipment which utilizes the ac and dc power. The pre-operational tests are performed after appropriate construction tests

  17. Waste water processing technology for Space Station Freedom - Comparative test data analysis

    Science.gov (United States)

    Miernik, Janie H.; Shah, Burt H.; Mcgriff, Cindy F.

    1991-01-01

    Comparative tests were conducted to choose the optimum technology for waste water processing on SSF. A thermoelectric integrated membrane evaporation (TIMES) subsystem and a vapor compression distillation subsystem (VCD) were built and tested to compare urine processing capability. Water quality, performance, and specific energy were compared for conceptual designs intended to function as part of the water recovery and management system of SSF. The VCD is considered the most mature and efficient technology and was selected to replace the TIMES as the baseline urine processor for SSF.

  18. The in-situ testing of high efficiency particulate filters in the CEGB south eastern region nuclear power stations

    International Nuclear Information System (INIS)

    Powell, A.W.; Wilkinson, B.A.

    1977-01-01

    High efficiency air filters are installed in the CEGB's Nuclear Power Stations to prevent discharge of radioactive material to the environment should the ventilation air become contaminated. The Board has determined that these filter units should be tested in-situ to ensure that the stringent design specifications are met. This paper describes the rig work comparing the British Standard method using sodium chloride aerosol with other test methods, such as Dioctyl Phthalate, naturally occurring dust aerosols and artificially produced condensation nuclei. This work led to the development of an in-situ test method using condensation nuclei and a Pollak-Nolan nucleus counter. The advantages and disadvantages of this method over other methods for in-situ testing is discussed. The test method has been used in the South Eastern Region for several years and considerable experience has been gained in its use on a wide variety of filter systems. The method adopted for each system is detailed including the injection, sampling and interpretation of the results obtained. Numerous faults and difficulties have been highlighted from the design, installation and filter changing aspects

  19. Morphoagrobiological properties and productivity of new soft winter wheat varieties under the conditions of Kirovohrad variety testing station

    Directory of Open Access Journals (Sweden)

    О. Л. Уліч

    2017-03-01

    Full Text Available Purpose. To study morphoagrobiological and adaptive properties, level of yielding capacity of recently registered soft winter wheat varieties of various ecological groups under agroecological conditions of Kirovohrad variety testing station. Methods. Field study, laboratory test, analytical procedure and statistical evaluation. Results. It was established that the yield level of is a key composite indicator of genotype adaptation to agroecological growing conditions. Experimental data indicate significant deviations of yield depending on the genotype and the year of study. During three years of experiments, yield depending of the variety ranged from 4.26 to 9.71 t/ha, such varieties as ‘CN Kombin’, ‘Estivus’, ‘Tradytsiia odeska’, ‘Mudrist odeska’, ‘Lil’ and ‘Fabius’ had higher yields. In case of dry weather conditions and unfavorable agro-ecological factors, the following varieties as ‘Mudrist odeska’, ‘Veteran’, ‘Lil’, ‘Tsentylivka’, ‘Fabius’, ‘Patras’, ‘Montrei’ have demonstrated good adaptive properties. Their yield has decreased by 9,2–19,0%, while in the varieties ‘Mahistral’, ‘Poltavka’, ‘Harantiia odeska’ and ‘Pokrova’ – by 34.4, 42.4, 45.2 and 50.6% accordingly. Conclusions. Investigated soft winter wheat varieties differ in morphoagrobiological characteristics, productivity, height, maturation period, adaptability as well as economic and agronomic value. According to the complex of such indices as productivity, agronomic characters and properties as well as adaptability, in the microzone of Kirovohrad variety testing station it is advisable to grow varie­ties ‘CN Kombi’, ‘Pokrova’, ‘Mudrist odeska’, ‘Veteran’ and ‘Lil’.

  20. Vehicle Impact Testing of Snow Roads at McMurdo Station, Antarctica

    Science.gov (United States)

    2014-06-01

    especially during warm weather when their high flotation tires al- low greater over-snow mobility. Table 2. Test vehicle information. Vehicle Vehicle...potential danger to the vehicle and pax 16 ERDC/CRREL TR-14-9 51 GO SLOWTI-U<OtJG-ISBTFOR YOLH?. SAFETY LANE C SCOTT BASE TRANSIT/ONTO SILVER

  1. Space station common module thermal management: Design and construction of a test bed

    Science.gov (United States)

    Barile, R. G.

    1986-01-01

    In this project, a thermal test bed was designed, simulated, and planned for construction. The thermal system features interior and exterior thermal loads and interfacing with the central-radiator thermal bus. Components of the test bed include body mounted radiator loop with interface heat exchangers (600 Btu/hr); an internal loop with cabin air-conditioning and cold plates (3400 Btu/hr); interface heat exchangers to the central bus (13,000 Btu/hr); and provisions for new technology including advanced radiators, thermal storage, and refrigeration. The apparatus will be mounted in a chamber, heated with lamps, and tested in a vacuum chamber with LN2-cooled walls. Simulation of the test bed was accomplished using a DEC PRO 350 computer and the software package TK! olver. Key input variables were absorbed solar radiation and cold plate loads. The results indicate temperatures on the two loops will be nominal when the radiation and cold plate loads are in the range of 25% to 75% of peak loads. If all loads fall to zero, except the cabin air system which was fixed, the radiator fluid will drop below -100 F and may cause excessive pressure drop. If all loads reach 100%, the cabin air temperature could rise to 96 F.

  2. Guideline on in-service testing (IST) of ECCS for nuclear power stations in Japan

    International Nuclear Information System (INIS)

    Yamashita, N.; Honjin, M.; Yamazaki, M.; Iwami, H.

    2001-01-01

    In Japan, METI (Ministry of Economy, Trade and Industry) periodic inspections are conducted every 13 months in accordance with the EUIL (Electric Utility Industry Law) for light water reactors. On the other hand, during operation, many kinds of function tests are conducted in accordance with Technical Specifications or utilities voluntary test procedures. However, these maintenance activities during outages are in other respects considered too costly and more than necessary because of its predetermined maintenance interval and its old-fashioned full scope maintenance menu. In these circumstances, the ASME O and M Codes and Standards, which are applied to nuclear power plants in the United States, came to be one of the issues to be considered among Japanese utilities. This is because the ASME O and M Codes and Standards, which are developed to verify the operational readiness of equipment or systems by condition based maintenance or performance testing without overhauls, will be considered to suggest a rational alternative to our existing maintenance activities. Because there had been no standard for function tests other than the METI inspection procedures in Japan, activities started for the development of Japanese Operation and Maintenance Guideline (hereinafter called the Japanese OM Guideline or the Guideline) for function tests and condition monitoring. The Japanese OM Guideline is not proclaimed for regulatory use, but the long-term objective is to provide a substantial basis to change the current maintenance activities including regulatory inspection. The Guideline is composed of five parts, which are general requirements, pumps, valves, snubbers and ECCS systems. This paper gives a summary of the ECCS part of the Japanese OM Guideline, in particular, focusing on the differences between the Guideline and the ASME O and M Standards, and topics or discussion during their establishment. (author)

  3. Principal facts of gravity stations with gravity and magnetic profiles from the southwest Nevada Test Site, Nye County, Nevada, as of January 1982

    International Nuclear Information System (INIS)

    Jansma, P.E.; Snyder, D.B.; Ponce, D.A.

    1983-01-01

    Three gravity profiles and principal facts of 2604 gravity stations in the southwest quadrant of the Nevada Test Site are documented in this data report. The residual gravity profiles show the gravity measurements and the smoothed curves derived from these points that were used in geophysical interpretations. The principal facts include station label, latitude, longitude, elevation, observed gravity value, and terrain correction for each station as well as the derived complete Bouguer and isostatic anomalies, reduced at 2.67 g/cm 3 . Accuracy codes, where available, further document the data

  4. Gas and water permeability tests of 25 year old concrete from the NPD Nuclear Generating Station

    International Nuclear Information System (INIS)

    Mills, R.H.

    1990-05-01

    Permeability tests on cores recovered from concrete which had been in service for 25 years in the Nuclear Power Demonstration (NPD) reactor showed rates of mass transfer of gas and water which were greater than young fresh concrete of the same proportions and that reported in previous AECB reports. This transparency of the concrete was also 2 orders of magnitude greater than that of comparable concrete which had been stored in the laboratory atmosphere for 19 years. Analysis of the effluent in water permeability tests revealed the presence of unusual amounts of soluble materials, mainly Na and K but little Ca, in the reactor concrete. This suggested service-related deterioration of the concrete rather than the release of soluble Ca by continuing hydration of cement

  5. IEEE Std 600: IEEE trial-use standard requirements for organizations that conduct qualification testing of safety systems equipment for use in nuclear power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    The purpose of this standard is to provide requirements for establishing a program for conducting qualification tests of safety systems equipment used in nuclear power generating stations. Compliance with the requirements of this standard does not assure the adequacy of the qualification tests performed. This standard applies to organizations that conduct qualification tests on equipment that has a definable safety function and is an identifiable part of a safety system for use in nuclear power generating stations. It requires a technical program, a quality assurance program, and a demonstrated ability to meet specified technical requirements. It does not apply to materials tests, production tests, normal performance testing, qualification by analysis, qualification by operating experience, or reliability tests such as diesel-generator multiple start tests. The intent of this standard is to achieve greater consistency, reliability, and reproducibility of test results and to provide adequate control of qualification testing of safety systems equipment

  6. Electrophysiological measurements of diabetic peripheral neuropathy: A systematic review.

    Science.gov (United States)

    Shabeeb, Dheyauldeen; Najafi, Masoud; Hasanzadeh, Gholamreza; Hadian, Mohammed Reza; Musa, Ahmed Eleojio; Shirazi, Alireza

    2018-03-28

    Peripheral neuropathy is one of the main complications of diabetes mellitus. One of the features of diabetic nerve damage is abnormality of sensory and motor nerve conduction study. An electrophysiological examination can be reproduced and is also a non-invasive approach in the assessment of peripheral nerve function. Population-based and clinical studies have been conducted to validate the sensitivity of these methods. When the diagnosis was based on clinical electrophysiological examination, abnormalities were observed in all patients. In this research, using a review design, we reviewed the issue of clinical electrophysiological examination of diabetic peripheral neuropathy in articles from 2008 to 2017. For this purpose, PubMed, Scopus and Embase databases of journals were used for searching articles. The researchers indicated that diabetes (both types) is a very disturbing health issue in the modern world and should be given serious attention. Based on conducted studies, it was demonstrated that there are different procedures for prevention and treatment of diabetes-related health problems such as diabetic polyneuropathy (DPN). The first objective quantitative indication of the peripheral neuropathy is abnormality of sensory and motor nerve conduction tests. Electrophysiology is accurate, reliable and sensitive. It can be reproduced and also is a noninvasive approach in the assessment of peripheral nerve function. The methodological review has found that the best method for quantitative indication of the peripheral neuropathy compared with all other methods is clinical electrophysiological examination. For best results, standard protocols such as temperature control and equipment calibration are recommended. Copyright © 2018. Published by Elsevier Ltd.

  7. Determination of neutron energy spectrum at a pneumatic rabbit station of a typical swimming pool type material test research reactor

    International Nuclear Information System (INIS)

    Malkawi, S.R.; Ahmad, N.

    2002-01-01

    The method of multiple foil activation was used to measure the neutron energy spectrum, experimentally, at a rabbit station of Pakistan Research Reactor-1 (PARR-1), which is a typical swimming pool type material test research reactor. The computer codes MSITER and SANDBP were used to adjust the spectrum. The pre-information required by the adjustment codes was obtained by modelling the core and its surroundings in three-dimensions by using the one dimensional transport theory code WIMS-D/4 and the multidimensional finite difference diffusion theory code CITATION. The input spectrum covariance information required by MSITER code was also calculated from the CITATION output. A comparison between calculated and adjusted spectra shows a good agreement

  8. The development and testing of a volatile organics concentrator for use in monitoring Space Station water quality

    Science.gov (United States)

    Bodek, Itamar; Ehntholt, Daniel J.; Stolki, Thomas J.; Trabanino, Rudy; Hinsdale, Lloyd; Webb, Johanna; Sauer, Richard L.

    1992-01-01

    The Volatile Organics Concentrator (VOC) system, designed to attach to a gas chromatograph/mass spectrometer (GC/MS) for the analyses of volatile organic compounds in water on Space Station Freedom, is described. Organic volatiles are collected and concentrated in the VOC by means of two primary solid sorbent tubes and desorbed into the GC/MS system. The paper describes the results of testing the VOC breadboard using a GC/MS system. Evaluations performed on 39 organic compounds recovered from water samples were compared with data for these compounds using direct injection/GC/MS and purge and trap/GC/MS procedures. The results demonstrate that the VOC/GC/MS system's detection limits for the 39 compounds analyzed are comparable to those of the EPA Method 524.2, and for many compounds reaching a factor of 5 lower.

  9. Construction and start-up tests for Unit No. 5 of Fukushima Daiichi Nuclear Power Station

    Energy Technology Data Exchange (ETDEWEB)

    Fujita, T; Sunami, Y; Ishii, N; Yokojima, T [Toshiba Corp., Kawasaki, Kanagawa (Japan)

    1978-12-01

    This unit, with an output capacity of 874 MWe, was completed by Toshiba last April on the basis of the actual operation records of the units previously completed and the experience in construction. Since its completion it has continued very excellent operation, with no emergency stop. This article is a description of the Unit 5, about: (1) the design and major points of improvement; (2) the construction work and cleaning of the plant; and (3) the operation tests, the use of the first automatic fuel exchanger, and the plant management system including the rust-preventive measures for two years since the oil-crisis.

  10. Development and qualification of a thermal-hydraulic nodalization for modeling station blackout accident in PSB-VVER test facility

    Energy Technology Data Exchange (ETDEWEB)

    Saghafi, Mahdi [Department of Energy Engineering, Sharif University of Technology, Azadi Avenue, Tehran (Iran, Islamic Republic of); Ghofrani, Mohammad Bagher, E-mail: ghofrani@sharif.edu [Department of Energy Engineering, Sharif University of Technology, Azadi Avenue, Tehran (Iran, Islamic Republic of); D’Auria, Francesco [San Piero a Grado Nuclear Research Group (GRNSPG), University of Pisa, Via Livornese 1291, San Piero a Grado, Pisa (Italy)

    2016-07-15

    Highlights: • A thermal-hydraulic nodalization for PSB-VVER test facility has been developed. • Station blackout accident is modeled with the developed nodalization in MELCOR code. • The developed nodalization is qualified at both steady state and transient levels. • MELCOR predictions are qualitatively and quantitatively in acceptable range. • Fast Fourier Transform Base Method is used to quantify accuracy of code predictions. - Abstract: This paper deals with the development of a qualified thermal-hydraulic nodalization for modeling Station Black-Out (SBO) accident in PSB-VVER Integral Test Facility (ITF). This study has been performed in the framework of a research project, aiming to develop an appropriate accident management support tool for Bushehr nuclear power plant. In this regard, a nodalization has been developed for thermal-hydraulic modeling of the PSB-VVER ITF by MELCOR integrated code. The nodalization is qualitatively and quantitatively qualified at both steady-state and transient levels. The accuracy of the MELCOR predictions is quantified in the transient level using the Fast Fourier Transform Base Method (FFTBM). FFTBM provides an integral representation for quantification of the code accuracy in the frequency domain. It was observed that MELCOR predictions are qualitatively and quantitatively in the acceptable range. In addition, the influence of different nodalizations on MELCOR predictions was evaluated and quantified using FFTBM by developing 8 sensitivity cases with different numbers of control volumes and heat structures in the core region and steam generator U-tubes. The most appropriate case, which provided results with minimum deviations from the experimental data, was then considered as the qualified nodalization for analysis of SBO accident in the PSB-VVER ITF. This qualified nodalization can be used for modeling of VVER-1000 nuclear power plants when performing SBO accident analysis by MELCOR code.

  11. Testing the sampling efficiency of a nuclear power station stack monitor

    Energy Technology Data Exchange (ETDEWEB)

    Stroem, L.H. [Instrumentinvest, Nykoeping (Sweden)

    1997-08-01

    The test method comprises the injection of known amounts of monodisperse particles in the stack air stream, at a suitable point upstream of the sampling installation. To find a suitable injection polls, the gas flow was mapped by means of a tracer gas, released in various points in the stack base. The resulting concentration distributions at the stack sampler level were observed by means of an array of gas detectors. An injection point that produced symmetrical distribution over the stack area, and low concentrations at the stack walls was selected for the particle tests. Monodisperse particles of 6, 10, and 19 {mu}m aerodynamic diameter, tagged with dysprosium, were dispersed in the selected injection point. Particle concentration at the sampler level was measured. The losses to the stack walls were found to be less than 10 %. The particle concentrations at the four sampler inlets were calculated from the observed gas distribution. The amount calculated to be aspirated into the sampler piping was compared with the quantity collected by the sampling train ordinary filter, to obtain the sampling line transmission efficiency. 1 ref., 2 figs.

  12. Base Station Performance Model

    OpenAIRE

    Walsh, Barbara; Farrell, Ronan

    2005-01-01

    At present the testing of power amplifiers within base station transmitters is limited to testing at component level as opposed to testing at the system level. While the detection of catastrophic failure is possible, that of performance degradation is not. This paper proposes a base station model with respect to transmitter output power with the aim of introducing system level monitoring of the power amplifier behaviour within the base station. Our model reflects the expe...

  13. Current concepts in nuclear pore electrophysiology.

    Science.gov (United States)

    Bustamante, José Omar

    2006-01-01

    Over 4 decades ago, microelectrode studies of in situ nuclei showed that, under certain conditions, the nuclear envelope (NE) behaves as a barrier opposing the nucleocytoplasmic flow of physiological ions. As the nuclear pore complexes (NPCs) of the NE are the only pathways for direct nucleocytoplasmic flow, those experiments implied that the NPCs are capable of restricting ion flow. These early studies validated electrophysiology as a useful approach to quantify some of the mechanisms by which NPCs mediate gene activity and expression. Since electron microscopy (EM) and other non-electrophysiological investigations, showed that the NPC lumen is a nanochannel, the opinion prevailed that the NPC could not oppose the flow of ions and, therefore, that electrophysiological observations resulted from technical artifacts. Consequently, the initial enthusiasm with nuclear electrophysiology faded out in less than a decade. In 1990, nuclear electrophysiology was revisited with patch-clamp, the most powerful electrophysiological technique to date. Patch-clamp has consistently demonstrated that the NE has intrinsic ion channel activity. Direct demonstrations of the NPC on-off ion channel gating behavior were published for artificial conditions in 1995 and for intact living nuclei in 2002. This on-off switching/gating behavior can be interpreted in terms of a metastable energy barrier. In the hope of advancing nuclear electrophysiology, and to complement the other papers contained in this special issue of the journal, here I review some of the main technical, experimental, and theoretical issues of the field, with special focus on NPCs.

  14. Tests of shielding effectiveness of Kevlar and Nextel onboard the International Space Station and the Foton-M3 capsule.

    Science.gov (United States)

    Pugliese, M; Bengin, V; Casolino, M; Roca, V; Zanini, A; Durante, M

    2010-08-01

    Radiation assessment and protection in space is the first step in planning future missions to the Moon and Mars, where mission and number of space travelers will increase and the protection of the geomagnetic shielding against the cosmic radiation will be absent. In this framework, the shielding effectiveness of two flexible materials, Kevlar and Nextel, were tested, which are largely used in the construction of spacecrafts. Accelerator-based tests clearly demonstrated that Kevlar is an excellent shield for heavy ions, close to polyethylene, whereas Nextel shows poor shielding characteristics. Measurements on flight performed onboard of the International Space Station and of the Foton-M3 capsule have been carried out with special attention to the neutron component; shielded and unshielded detectors (thermoluminescence dosemeters, bubble detectors) were exposed to a real radiation environment to test the shielding properties of the materials under study. The results indicate no significant effects of shielding, suggesting that thin shields in low-Earth Orbit have little effect on absorbed dose.

  15. Prototype Software for Future Spaceflight Tested at Mars Desert Research Station

    Science.gov (United States)

    Clancey, William J.; Sierhuis, Maaretn; Alena, Rick; Dowding, John; Garry, Brent; Scott, Mike; Tompkins, Paul; vanHoof, Ron; Verma, Vandi

    2006-01-01

    NASA scientists in MDRS Crew 49 (April 23-May 7, 2006) field tested and significantly extended a prototype monitoring and advising system that integrates power system telemetry with a voice commanding interface. A distributed, wireless network of functionally specialized agents interacted with the crew to provide alerts (e.g., impending shut-down of inverter due to low battery voltage), access md interpret historical data, and display troubleshooting procedures. In practical application during two weeks, the system generated speech over loudspeakers and headsets lo alert the crew about the need to investigate power system problems. The prototype system adapts the Brahms/Mobile Agents toolkit to receive data from the OneMeter (Brand Electronics) electric metering system deployed by Crew 47. A computer on the upper deck was connected to loudspeakers, four others were paired with wireless (Bluetooth) headsets that enabled crew members to interact with their personal agents from anywhere in the hab. Voice commands and inquiries included: 1. What is the {battery | generator} {volts | amps | volts and amps}? 2. What is the status of the {generator | inverter | battery | solar panel}? 3. What is the hab{itat} {power usage | volts | voltage | amps | volts and amps}? 4. What was the average hab{itat} {amps | volts | voltage} since {AM | PM)? 5. When did the {generator | batteries} change status? 6. Tell {me I | everyone} when{ ever} the generator goes offline. 7. Tell {me | | everyone} when the hab{itat} {amps | volts | voltage} {exceeds | drops brelow} . 8. {Send | Take | Record} {a} voice note {(for | to} } {at }. This research demonstrates the principles of design in the context of use, investigating requirements through experimental use of prototype systems in an analog setting, and use of MDRS as a research facility for designing and implementing new systems.

  16. Approach to the assessment of the performance of nondestructive test methods in the manufacture of nuclear power station equipment

    International Nuclear Information System (INIS)

    Michaut, J.P.

    1996-01-01

    The safety of a nuclear power station lies largely in the possibility of ensuring, at the time of in service inspections on major equipment, that the extent of faults which may appear or develop is not greater than that of faults detrimental to behavior in service. This assurance is based on performance demonstration of the nondestructive test methods used for inspecting the equipment in service. This is the subject of numerous studies in various countries. To ensure that manufacturing faults likely to downgrade the safety of the equipment are not discovered in service, it seems desirable to make sure that the performance of the nondestructive test (NDT) methods which are going to be used in manufacture will be at least as high as those used in service and that they are therefore capable of guaranteeing detection of faults clearly less important than really harmful faults. The performance of NDT methods and their consistency with those which can be used in service is evaluated before the start of manufacture on a mock-up representative of the equipment itself. Information is given on research in progress on the bimetal welding of a pressurizer spray nozzle

  17. Field pilot testing for chemical oxidation at the former Nitchequon meteorological station : decontamination project in isolated areas

    Energy Technology Data Exchange (ETDEWEB)

    Peisajovich, A. [Transport Canada, Montreal, PQ (Canada); Bergeron, E. [Golder Associates Ltd., Montreal, PQ (Canada); Barbeau, M. [Golder Associates Innovative Applications, Montreal, PQ (Canada); Lajoie, G. [Cree Regional Authority, Montreal, PQ (Canada)

    2006-07-01

    Field pilot testing for chemical oxidation at the former Nitchequon meteorological station was discussed. This presentation described the site location and provided an aerial view and cross section of the site. The historical background and condition of the site were then identified. Photographs and illustrations of the site and the source of the problem were provided. Photographs were also provided of the logistics, temporary camp, dismantling of tanks, equipment, pipeline dismantling, residues, methodology as well as a graphical representation of how to solve the problem. Other topics included technologies tested on site, full-scale remediation plans, remediation goals, step by step process, and costs distribution. Among the steps discussed was: vegetation removal; excavation of the first two feet of soil; transfer of contaminated soil on high-density polyethylene (HDPE) lining prior to treatment; cell construction; cell lining insulation; transfer of treated soil from the mixers to the curing cells; installation of HDPE top cover lining over the treated soil; and the addition of 12 inches of clean soil over the top cover lining. tabs., figs.

  18. Pelvic floor electrophysiology patterns associated with faecal ...

    African Journals Online (AJOL)

    Hussein Al-Moghazy Sultan

    2012-12-28

    Dec 28, 2012 ... pelvic floor electrophysiological abnormalities associated with. FI were illustrated in ... detection of a localized anal sphincter defect clinically and ..... Woods R, Voyvodic F, Schloithe A, Sage M, Wattchow D. Anal sphincter ...

  19. Field Testing of Activated Carbon Injection Options for Mercury Control at TXU's Big Brown Station

    Energy Technology Data Exchange (ETDEWEB)

    John Pavlish; Jeffrey Thompson; Christopher Martin; Mark Musich; Lucinda Hamre

    2009-01-07

    The primary objective of the project was to evaluate the long-term feasibility of using activated carbon injection (ACI) options to effectively reduce mercury emissions from Texas electric generation plants in which a blend of lignite and subbituminous coal is fired. Field testing of ACI options was performed on one-quarter of Unit 2 at TXU's Big Brown Steam Electric Station. Unit 2 has a design output of 600 MW and burns a blend of 70% Texas Gulf Coast lignite and 30% subbituminous Powder River Basin coal. Big Brown employs a COHPAC configuration, i.e., high air-to-cloth baghouses following cold-side electrostatic precipitators (ESPs), for particulate control. When sorbent injection is added between the ESP and the baghouse, the combined technology is referred to as TOXECON{trademark} and is patented by the Electric Power Research Institute in the United States. Key benefits of the TOXECON configuration include better mass transfer characteristics of a fabric filter compared to an ESP for mercury capture and contamination of only a small percentage of the fly ash with AC. The field testing consisted of a baseline sampling period, a parametric screening of three sorbent injection options, and a month long test with a single mercury control technology. During the baseline sampling, native mercury removal was observed to be less than 10%. Parametric testing was conducted for three sorbent injection options: injection of standard AC alone; injection of an EERC sorbent enhancement additive, SEA4, with ACI; and injection of an EERC enhanced AC. Injection rates were determined for all of the options to achieve the minimum target of 55% mercury removal as well as for higher removals approaching 90%. Some of the higher injection rates were not sustainable because of increased differential pressure across the test baghouse module. After completion of the parametric testing, a month long test was conducted using the enhanced AC at a nominal rate of 1.5 lb/Macf. During

  20. Demonstration test of electron beam flue gas treatment pilot plant of a coal fired thermal power station

    International Nuclear Information System (INIS)

    Doi, Yoshitaka; Hayashi, Kazuaki; Izutsu, Masahiro; Watanabe, Shigeharu; Namba, Hideki; Tokunaga, Okihiro; Hashimoto, Shoji; Tanaka, Tadashi; Ogura, Yoshimi.

    1995-01-01

    The Japan Atomic Energy Research Institute, Chubu Electric Power Company and Ebara Corporation jointly constructed a pilot plant for electron beam flue gas treatment (dry process) capable of treating 12,000 m 3 /h (NTP) of flue gas from a coal fired boiler, at Shin-Nagoya Thermal Power Station, Chubu Electric Power Company. Various tests carried out at the plant over a period extending one year verified the followings. By appropriately controlling parameters such as electron beam dosage, flue gas temperature, and ammonia stoichiometric amount, highly efficient simultaneous SO 2 and NOx removal from flue gas was achieved under all gas conditions, equal to or more efficient than that by the highest level conventional treatment. The operation of the pilot plant was stable and trouble-free over a long term, and the operation and the process was easy to operate and control. By-products (ammonium sulfate and ammonium nitrate) produced by the flue gas treatment were proven to have superior quality, equivalent to that of market-available nitrogen fertilizers. These by-products had been registered as by-product nitrogen fertilizers. (author)

  1. The International Space Station: A Low-Earth Orbit (LEO) Test Bed for Advancements in Space and Environmental Medicine

    Science.gov (United States)

    Ruttley, Tara M.; Robinson, Julie A.

    2010-01-01

    Ground-based space analog projects such as the NASA Extreme Environment Mission Operations (NEEMO) can be valuable test beds for evaluation of experimental design and hardware feasibility before actually being implemented on orbit. The International Space Station (ISS) is an closed-system laboratory that orbits 240 miles above the Earth, and is the ultimate extreme environment. Its inhabitants spend hours performing research that spans from fluid physics to human physiology, yielding results that have implications for Earth-based improvements in medicine and health, as well as those that will help facilitate the mitigation of risks to the human body associated with exploration-class space missions. ISS health and medical experiments focus on pre-flight and in-flight prevention, in-flight treatment, and postflight recovery of health problems associated with space flight. Such experiments include those on enhanced medical monitoring, bone and muscle loss prevention, cardiovascular health, immunology, radiation and behavior. Lessons learned from ISS experiments may not only be applicable to other extreme environments that face similar capability limitations, but also serve to enhance standards of care for everyday use on Earth.

  2. Overview of Microbiological Tests Performed During the Design of the International Space Station Environmental Control and Life Support Systems

    Science.gov (United States)

    Roman, Monsi C.; Mittelman, Marc W.

    2010-01-01

    The design and manufacturing of the main Environmental Control and Life Support Systems (ECLSS) for the United States segments of the International Space Station (ISS) was an involved process that started in the late 1980's, with the assessment and testing of competing technologies that could be used to clean the air and recycle water. It culminated in 2009 with the delivery and successful activation of the Water Recovery System (WRS) water processor (WP). The ECLSS required the work of a team of engineers and scientist working together to develop systems that could clean and/or recycle human metabolic loads to maintain a clean atmosphere and provide the crew clean water. One of the main goals of the ECLSS is to minimize the time spent by the crew worrying about vital resources not available in the vacuum of space, which allows them to spend most of their time learning to live in a microgravity environment many miles from the comforts of Earth and working on science experiments. Microorganisms are a significant part of the human body as well as part of the environment that we live in. Therefore, the ISS ECLSS design had to take into account the effect microorganisms have on the quality of stored water and wastewater, as well as that of the air systems. Hardware performance issues impacted by the accumulation of biofilm and/or microbiologically influenced corrosion were also studied during the ECLSS development stages. Many of the tests that were performed had to take into account the unique aspects of a microgravity environment as well as the challenge of understanding how to design systems that could not be sterilized or maintained in a sterile state. This paper will summarize the work of several studies that were performed to assess the impacts and/or to minimize the effects of microorganisms in the design of a closed loop life support system.

  3. Corrective Action Investigation Plan for Corrective Action Unit 321: Area 22 Weather Station Fuel Storage, Nevada Test Site, Nevada; TOPICAL

    International Nuclear Information System (INIS)

    1999-01-01

    This Corrective Action Investigation Plan (CAIP) has been developed in accordance with the Federal Facility Agreement and Consent Order (FFACO) that was agreed to by the US Department of Energy, Nevada Operations Office (DOE/NV); the State of Nevada Division of Environmental Protection (NDEP); and the US Department of Defense (FFACO, 1996). The CAIP is a document that provides or references all of the specific information for investigation activities associated with Corrective Action Units (CAUs) or Corrective Action Sites (CASs). According to the FFACO (1996), CASs are sites potentially requiring corrective action(s) and may include solid waste management units or individual disposal or release sites. A CAU consists of one or more CASs grouped together based on geography, technical similarity, or agency responsibility for the purpose of determining corrective actions. This CAIP contains the environmental sample collection objectives and the criteria for conducting site investigation activities at the CAU 321 Area 22 Weather Station Fuel Storage, CAS 22-99-05 Fuel Storage Area. For purposes of this discussion, this site will be referred to as either CAU 321 or the Fuel Storage Area. The Fuel Storage Area is located in Area 22 of the Nevada Test Site (NTS). The NTS is approximately 105 kilometers (km) (65 miles[mi]) northwest of Las Vegas, Nevada (Figure 1-1) (DOE/NV, 1996a). The Fuel Storage Area (Figure 1-2) was used to store fuel and other petroleum products necessary for motorized operations at the historic Camp Desert Rock facility which was operational from 1951 to 1958 at the Nevada Test Site, Nevada. The site was dismantled after 1958 (DOE/NV, 1996a)

  4. Wearable carbon nanotube based dry-electrodes for electrophysiological sensors

    Science.gov (United States)

    Kang, Byeong-Cheol; Ha, Tae-Jun

    2018-05-01

    In this paper, we demonstrate all-solution-processed carbon nanotube (CNT) dry-electrodes for the detection of electrophysiological signals such as electrocardiograms (ECG) and electromyograms (EMG). The key parameters of P, Q, R, S, and T peaks are successfully extracted by such CNT based dry-electrodes, which is comparable with conventional silver/chloride (Ag/AgCl) wet-electrodes with a conducting gel film for the ECG recording. Furthermore, the sensing performance of CNT based dry-electrodes is secured during the bending test of 200 cycles, which is essential for wearable electrophysiological sensors in a non-invasive method on human skin. We also investigate the application of wearable CNT based dry-electrodes directly attached to the human skins such as forearm for sensing the electrophysiological signals. The accurate and rapid sensing response can be achieved by CNT based dry-electrodes to supervise the health condition affected by excessive physical movements during the real-time measurements.

  5. Electrophysiological study in neuromuscular junction disorders

    Directory of Open Access Journals (Sweden)

    Ajith Cherian

    2013-01-01

    Full Text Available This review is on ultrastructure and subcellular physiology at normal and abnormal neuromuscular junctions. The clinical and electrophysiological findings in myasthenia gravis, Lambert-Eaton myasthenic syndrome (LEMS, congenital myasthenic syndromes, and botulinum intoxication are discussed. Single fiber electromyography (SFEMG helps to explain the basis of testing neuromuscular junction function by repetitive nerve stimulation (RNS. SFEMG requires skill and patience and its availability is limited to a few centers. For RNS supramaximal stimulation is essential and so is display of the whole waveform of each muscle response at maximum amplitude. The amplitudes of the negative phase of the first and fourth responses are measured from baseline to negative peak, and the percent change of the fourth response compared with the first represents the decrement or increment. A decrement greater than 10% is accepted as abnormal and smooth progression of response amplitude train and reproducibility form the crux. In suspected LEMS the effect of fast rates of stimulation should be determined after RNS response to slow rates of stimulation. Caution is required to avoid misinterpretation of potentiation and pseudofacilitation.

  6. Analysis of technological innovation in Danish wind turbine industry - including the Test Station for Windturbines dual roll as research institution and certification authority

    International Nuclear Information System (INIS)

    Dannemand Andersen, P.

    1993-01-01

    The overall aim of this thesis is to examine the interactions between the Danish wind turbine industry and the Test Station for Wind Turbines. Because these interactions are concerning technological innovation, it follows that the innovation processes within the enterprises must be analyzed and modelled. The study is carried out as an iterative model-developing process using case study methods. The findings from some less structured interviews are discussed with literature and forms a basis for models and new interviews. The thesis is based on interviews with 20 R and D engineers in the Danish wind turbine industry, 7 engineers at The Test Station and 7 people involved in wind power abroad (American and British). The theoretical frame for this thesis is sociology/organizational theory and industrial engineering. The thesis consists of five main sections, dealing with technology and knowledge, innovation processes, organizational culture, innovation and interaction between the Test Station's research activities and the companies' innovation processes, and finally interaction through the Test Stations certification activity. First a taxonomy for technology and knowledge is established in order to clarify what kind of technology the interactions are all about, and what kind of knowledge is transferred during the interactions. This part of the thesis also contains an analysis of the patents drawn by the Danish wind turbine industry. The analysis shows that the Danish wind turbine industry do not use patents. Instead the nature of the technology and the speed of innovation are used to protect the industry's knowledge. (EG) (192 refs.)

  7. Test des photomultiplicateurs en silicium couplés à un scintillateur plastique pour la nouvelle Tape Station

    CERN Document Server

    sekal, Smain

    2014-01-01

    L’une des parties essentielles de la l’installation ISOLDE est la tape Station (contrôleur de bandes), qui permet la vérification de la qualité du faisceau délivré aux expériences. On prévoit à ISOLDE de remplacer l’ancienne Tape Station, par une nouvelle Tape station; et l’un des paramètres essentiels pour la performance de la tape Station est l’efficacité de détection. Le but de ce travail est de vérifier l’efficacité des détecteurs de particules bêta, composés par l’association des photomultiplicateurs en Silicium à un scintillateur plastique pour differentes distances.

  8. Tests of a new CCD-camera based neutron radiography detector system at the reactor stations in Munich and Vienna

    Energy Technology Data Exchange (ETDEWEB)

    Lehmann, E; Pleinert, H [Paul Scherrer Inst. (PSI), Villigen (Switzerland); Schillinger, B [Technische Univ. Muenchen (Germany); Koerner, S [Atominstitut der Oesterreichischen Universitaeten, Vienna (Austria)

    1997-09-01

    The performance of the new neutron radiography detector designed at PSI with a cooled high sensitive CCD-camera was investigated under real neutronic conditions at three beam ports of two reactor stations. Different converter screens were applied for which the sensitivity and the modulation transfer function (MTF) could be obtained. The results are very encouraging concerning the utilization of this detector system as standard tool at the radiography stations at the spallation source SINQ. (author) 3 figs., 5 refs.

  9. IEEE Std 383-1974: IEEE standard for type test of Class IE electric cables, field splices, and connections for nuclear power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This standard provides direction for establishing type tests which may be used in qualifying Class 1E electric cables, field splices, and other connections for service in nuclear power generating stations. General guidelines for qualifications are given in IEEE Std 323-1974, Standard for Qualifying Class IE Electric Equipment for Nuclear Power Generating Stations. Categories of cables covered are those used for power control and instrumentation services. Though intended primarily to pertain to cable for field installation, this guide may also be used for the qualification of internal wiring of manufactured devices. This guide does not cover cables for service within the reactor vessel

  10. Fire Stations

    Data.gov (United States)

    Department of Homeland Security — Fire Stations in the United States Any location where fire fighters are stationed or based out of, or where equipment that such personnel use in carrying out their...

  11. Gas recovery and self-testing systm in gasoline stations. Execution of practical field tests / phase of tests in the wholistic system; Gasrueckfuehrung und selbstueberwachende Systeme an Tankstellen. Durchfuehrung von praktischen Feldtests/Testphase im ganzheitlichen System

    Energy Technology Data Exchange (ETDEWEB)

    Altmann, B.R.; Kunter, S.; Maurer, C.; Schneider, T.; Schrittenlacher, W.; Maahsen, H.; Arts, M.

    2003-04-01

    The amendment of the 21{sup st} Regulation on Air-Pollution Control dated 17.05.2002 describes continuous control of the function of gas recovery systems in gasoline stations by automatic control systems. Both systems available in the market (supplied by FAFNIR and TOKHEIM) were tested in extensive field tests. Both systems are ready for mass production. New dispensers are delivered with self control systems per production-type since 1.04.2003. Supplementary kits for the different dispenser types are available. (orig.)

  12. Applicability of AWJ technique for dismantling reactor of the Fukushima Daiichi Nuclear Power Station. Cutting test of imitation of fuel debris and optimization of the cutting condition

    International Nuclear Information System (INIS)

    Maruyama, Shin-ichiro; Watatani, Satoshi

    2016-01-01

    Based on findings during recovery works that followed the accident at Three Mile Island Station 2, it is assumed that the reactor internals at the Fukushima Daiichi Nuclear Power Station (1F) have complex geometries intermixed with melted fuel and confined in limited spaces. Accordingly, abrasive water jet (AWJ) cutting method is considered to be a promising technique that can be safely and reasonably used for cutting and removing reactor internals. The authors conducted tests to examine the possibility of application and to solve the problems of this technique. In the tests imitation of fuel debris and optimization of the cutting condition is used. The test result made the measures for some of the associated issues clear, and demonstrated that AWJ cutting method is assumed as one of the promising techniques for removing reactor internals. (author)

  13. Electrophysiological Basis of Fecal Incontinence and Its Implications for Treatment

    Science.gov (United States)

    2017-01-01

    The majority of patients with neuropathic incontinence and other pelvic floor conditions associated with straining at stool have damage to the pudendal nerves distal to the ischial spine. Sacral nerve stimulation appears to be a promising innovation and has been widely adopted and currently considered the standard of care for adults with moderate to severe fecal incontinence and following failed sphincter repair. From a decision-to-treat perspective, the short-term efficacy is good (70%–80%), but the long-term efficacy of sacral nerve stimulation is around 50%. Newer electrophysiological tests and improved anal endosonography would more effectively guide clinical decision making. PMID:29159162

  14. Technical evaluation of the noise and isolation testing of the safety features actuation system at the Davis Besse Nuclear Power Station, Unit 1

    International Nuclear Information System (INIS)

    Selan, J.C.

    1981-07-01

    This report documents the technical evaluation of the noise and isolation testing of the safety features actuation system at the Davis Besse Nuclear Power Station, Unit 1. The tests were to verify that faults on the non-Class 1E circuits would not propagate to the Class 1E circuits and degrade them below acceptable levels. The tests conducted demonstrated that the safety features actuation system did not degrade below acceptable levels nor was the system's ability to perform its protective functions affected

  15. Peripheral Neuropathy – Clinical and Electrophysiological Considerations

    Science.gov (United States)

    Chung, Tae; Prasad, Kalpana; Lloyd, Thomas E.

    2013-01-01

    This article is a primer on the pathophysiology and clinical evaluation of peripheral neuropathy for the radiologist. Magnetic resonance neurography (MRN) has utility in the diagnosis of many focal peripheral nerve lesions. When combined with history, examination, electrophysiology, and laboratory data, future advancements in high-field MRN may play an increasingly important role in the evaluation of patients with peripheral neuropathy. PMID:24210312

  16. Radiological survey of the area surrounding the National Reactor Testing Station, Idaho Falls, Idaho. Date of survey: 1 and 2 February 1972

    International Nuclear Information System (INIS)

    1974-01-01

    The Aerial Radiological Measuring System (ARMS) was used to survey the National Reactor Testing Station (NRTS) during February 1972. The purpose of the survey was primarily to identify the presence of Ru-106 and Rh-106 in a release from the Chemical Processing Plant at NRTS. Additionally, the gamma-ray terrestrial exposure rate levels were mapped and the distribution of any man-made isotopes was located and defined

  17. Amtrak Stations

    Data.gov (United States)

    Department of Homeland Security — Updated database of the Federal Railroad Administration's (FRA) Amtrak Station database. This database is a geographic data set containing Amtrak intercity railroad...

  18. IEEE Std 381-1977: IEEE standard criteria for type tests of Class 1E modules used in nuclear power generating stations

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This document describes the basic requirements of a type test program with the objective of verifying that a module used as Class 1E equipment in a nuclear power generating station meets or exceeds its design specifications. This document is limited to class 1E modules from and including the sensor through the logic circuitry of the final actuation devices. Except for those that are part of a module, switchgear, cables, connections, motors, valve actuators, station batteries, and penetrations are not included and are covered by other IEEE documents. The purpose of this document is to supplement the procedures and requirements given in IEEE Std 323-1974 [24] for type testing Class 1E modules, thereby providing directions for establishment of a type test program which will obtain the required test data and yield the required documentation of test methods and results. This standard is structured to present to the user the principal performance characteristics and environmental parameters which must be considered in designing a type test program for any give Class 1E module. These modules range from tiny sensors to complete racks or cabinets full of equipment that may be located inside or outside containment. The Class 1E modules are required to perform their function before, during, or after, or all, any design basis event specified for the module. The vast variety of modules covered by this document precludes the listing here of specific requirements for each type test

  19. A test facility for the international linear collider at SLAC end station a for prototypes of beam delivery and IR components

    International Nuclear Information System (INIS)

    Hildreth, M.D.; Erickson, R.; Frisch, J.

    2006-01-01

    The SLAC Linac can deliver damped bunches with ILC parameters for bunch charge and bunch length to End Station A. A 10Hz beam at 28.5 GeV energy can be delivered there, parasitic with PEP-II operation. We plan to use this facility to test prototype components of the Beam Delivery System and Interaction Region. We discuss our plans for this ILC Test Facility and preparations for carrying out experiments related to collimator wakefields and energy spectrometers. We also plan an interaction region mockup to investigate effects from backgrounds and beam-induced electromagnetic interference. (author)

  20. Electrophysiological properties and calcium handling of embryonic stem cell-derived cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Jae Boum Youm

    2016-03-01

    Full Text Available Embryonic stem cell-derived cardiomyocytes (ESC-CMs hold great interest in many fields of research including clinical applications such as stem cell and gene therapy for cardiac repair or regeneration. ESC-CMs are also used as a platform tool for pharmacological tests or for investigations of cardiac remodeling. ESC-CMs have many different aspects of morphology, electrophysiology, calcium handling, and bioenergetics compared with adult cardiomyocytes. They are immature in morphology, similar to sinus nodal-like in the electrophysiology, higher contribution of trans-sarcolemmal Ca2+ influx to Ca2+ handling, and higher dependence on anaerobic glycolysis. Here, I review a detailed electrophysiology and Ca2+ handling features of ESC-CMs during differentiation into adult cardiomyocytes to gain insights into how all the developmental changes are related to each other to display cardinal features of developing cardiomyocytes.

  1. The Solid Waste Transfer Pit an FFTF [Fast Flux Test Facility] station for fuel and reflector transfer

    International Nuclear Information System (INIS)

    Milewski, A.J.; Thomson, J.D.

    1985-01-01

    This paper describes the design aspects of a proposed FFTF facility called the Solid Waste Transfer Pit (SWTP). This new facility will be used as a transfer station for reflectors and/or low decay heat fuel assemblies when movement from the Fuel Storage Facility for sodium removal and subsequent reprocessing is to be accomplished. The SWTP utilizes a shielded cell cover with an integral manually-operated gate valve for top loading of a transfer vessel. The cost-effective design discussed herein provides a practical approach using state-of-the-art concepts while assuring safe and reliable operation

  2. Re-visiting the electrophysiology of language.

    Science.gov (United States)

    Obleser, Jonas

    2015-09-01

    This editorial accompanies a special issue of Brain and Language re-visiting old themes and new leads in the electrophysiology of language. The event-related potential (ERP) as a series of characteristic deflections ("components") over time and their distribution on the scalp has been exploited by speech and language researchers over decades to find support for diverse psycholinguistic models. Fortunately, methodological and statistical advances have allowed human neuroscience to move beyond some of the limitations imposed when looking at the ERP only. Most importantly, we currently witness a refined and refreshed look at "event-related" (in the literal sense) brain activity that relates itself more closely to the actual neurobiology of speech and language processes. It is this imminent change in handling and interpreting electrophysiological data of speech and language experiments that this special issue intends to capture. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. Positive Behavioral and Electrophysiological Changes following Neurofeedback Training in Children with Autism

    Science.gov (United States)

    Pineda, J. A.; Brang, D.; Hecht, E.; Edwards, L.; Carey, S.; Bacon, M.; Futagaki, C.; Suk, D.; Tom, J.; Birnbaum, C.; Rork, A.

    2008-01-01

    Two electrophysiological studies tested the hypothesis that operant conditioning of mu rhythms via neurofeedback training can renormalize mu suppression, an index of mirror neuron activity, and improve behavior in children diagnosed with autism spectrum disorders (ASD). In Study 1, eight high-functioning ASD participants were assigned to placebo…

  4. Electrophysiological studies in healthy subjects involving caffeine

    OpenAIRE

    Carvalho, Mamede de; Marcelino, Erica; Mendonça, Alexandre de

    2010-01-01

    Copyright ©2012 IOS Press All rights reserved. We review the electrophysiological studies concerning the effects of caffeine on muscle, lower and upper motor neuron excitability and cognition. Several different methods have been used, such as electromyography, recruitment analysis, H-reflex, transcranial magnetic stimulation (TMS), electroencephalography and event-related potentials. The positive effect of caffeine on vigilance, attention, speed of reaction, information processing and arou...

  5. Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations

    OpenAIRE

    Costa, Caroline Mendonca; Hoetzl, Elena; Rocha, Bernardo Martins; Prassl, Anton J; Plank, Gernot

    2013-01-01

    Driven by recent advances in medical imaging, image segmentation and numerical techniques, computer models of ventricular electrophysiology account for increasingly finer levels of anatomical and biophysical detail. However, considering the large number of model parameters involved parameterization poses a major challenge. A minimum requirement in combined experimental and modeling studies is to achieve good agreement in activation and repolarization sequences between model and experiment or ...

  6. The reliability of commonly used electrophysiology measures.

    Science.gov (United States)

    Brown, K E; Lohse, K R; Mayer, I M S; Strigaro, G; Desikan, M; Casula, E P; Meunier, S; Popa, T; Lamy, J-C; Odish, O; Leavitt, B R; Durr, A; Roos, R A C; Tabrizi, S J; Rothwell, J C; Boyd, L A; Orth, M

    Electrophysiological measures can help understand brain function both in healthy individuals and in the context of a disease. Given the amount of information that can be extracted from these measures and their frequent use, it is essential to know more about their inherent reliability. To understand the reliability of electrophysiology measures in healthy individuals. We hypothesized that measures of threshold and latency would be the most reliable and least susceptible to methodological differences between study sites. Somatosensory evoked potentials from 112 control participants; long-latency reflexes, transcranial magnetic stimulation with resting and active motor thresholds, motor evoked potential latencies, input/output curves, and short-latency sensory afferent inhibition and facilitation from 84 controls were collected at 3 visits over 24 months at 4 Track-On HD study sites. Reliability was assessed using intra-class correlation coefficients for absolute agreement, and the effects of reliability on statistical power are demonstrated for different sample sizes and study designs. Measures quantifying latencies, thresholds, and evoked responses at high stimulator intensities had the highest reliability, and required the smallest sample sizes to adequately power a study. Very few between-site differences were detected. Reliability and susceptibility to between-site differences should be evaluated for electrophysiological measures before including them in study designs. Levels of reliability vary substantially across electrophysiological measures, though there are few between-site differences. To address this, reliability should be used in conjunction with theoretical calculations to inform sample size and ensure studies are adequately powered to detect true change in measures of interest. Copyright © 2017 Elsevier Inc. All rights reserved.

  7. International Space Station Sustaining Engineering: A Ground-Based Test Bed for Evaluating Integrated Environmental Control and Life Support System and Internal Thermal Control System Flight Performance

    Science.gov (United States)

    Ray, Charles D.; Perry, Jay L.; Callahan, David M.

    2000-01-01

    As the International Space Station's (ISS) various habitable modules are placed in service on orbit, the need to provide for sustaining engineering becomes increasingly important to ensure the proper function of critical onboard systems. Chief among these are the Environmental Control and Life Support System (ECLSS) and the Internal Thermal Control System (ITCS). Without either, life onboard the ISS would prove difficult or nearly impossible. For this reason, a ground-based ECLSS/ITCS hardware performance simulation capability has been developed at NASA's Marshall Space Flight Center. The ECLSS/ITCS Sustaining Engineering Test Bed will be used to assist the ISS Program in resolving hardware anomalies and performing periodic performance assessments. The ISS flight configuration being simulated by the test bed is described as well as ongoing activities related to its preparation for supporting ISS Mission 5A. Growth options for the test facility are presented whereby the current facility may be upgraded to enhance its capability for supporting future station operation well beyond Mission 5A. Test bed capabilities for demonstrating technology improvements of ECLSS hardware are also described.

  8. Muscle channelopathies and electrophysiological approach

    Directory of Open Access Journals (Sweden)

    Cherian Ajith

    2008-01-01

    Full Text Available Myotonic syndromes and periodic paralyses are rare disorders of skeletal muscle characterized mainly by muscle stiffness or episodic attacks of weakness. Familial forms are caused by mutation in genes coding for skeletal muscle voltage ionic channels. Familial periodic paralysis and nondystrophic myotonias are disorders of skeletal muscle excitability caused by mutations in genes coding for voltage-gated ion channels. These diseases are characterized by episodic failure of motor activity due to muscle weakness (paralysis or stiffness (myotonia. Clinical studies have identified two forms of periodic paralyses: hypokalemic periodic paralysis (hypoKPP and hyperkalemic periodic paralysis (hyperKPP, based on changes in serum potassium levels during the attacks, and three distinct forms of myotonias: paramyotonia congenita (PC, potassium-aggravated myotonia (PAM, and myotonia congenita (MC. PC and PAM have been linked to missense mutations in the SCN4A gene, which encodes α subunit of the voltage-gated sodium channel, whereas MC is caused by mutations in the chloride channel gene (CLCN1. Exercise is known to trigger, aggravate, or relieve symptoms. Therefore, exercise can be used as a functional test in electromyography to improve the diagnosis of these muscle disorders. Abnormal changes in the compound muscle action potential can be disclosed using different exercise tests. Five electromyographic (EMG patterns (I-V that may be used in clinical practice as guides for molecular diagnosis are discussed.

  9. Space Station galley design

    Science.gov (United States)

    Trabanino, Rudy; Murphy, George L.; Yakut, M. M.

    1986-01-01

    An Advanced Food Hardware System galley for the initial operating capability (IOC) Space Station is discussed. Space Station will employ food hardware items that have never been flown in space, such as a dishwasher, microwave oven, blender/mixer, bulk food and beverage dispensers, automated food inventory management, a trash compactor, and an advanced technology refrigerator/freezer. These new technologies and designs are described and the trades, design, development, and testing associated with each are summarized.

  10. National Seismic Station

    International Nuclear Information System (INIS)

    Stokes, P.A.

    1982-06-01

    The National Seismic Station was developed to meet the needs of regional or worldwide seismic monitoring of underground nuclear explosions to verify compliance with a nuclear test ban treaty. The Station acquires broadband seismic data and transmits it via satellite to a data center. It is capable of unattended operation for periods of at least a year, and will detect any tampering that could result in the transmission of unauthentic seismic data

  11. Evaluation of the expected moments algorithm and a multiple low-outlier test for flood frequency analysis at streamgaging stations in Arizona

    Science.gov (United States)

    Paretti, Nicholas V.; Kennedy, Jeffrey R.; Cohn, Timothy A.

    2014-01-01

    Flooding is among the costliest natural disasters in terms of loss of life and property in Arizona, which is why the accurate estimation of flood frequency and magnitude is crucial for proper structural design and accurate floodplain mapping. Current guidelines for flood frequency analysis in the United States are described in Bulletin 17B (B17B), yet since B17B’s publication in 1982 (Interagency Advisory Committee on Water Data, 1982), several improvements have been proposed as updates for future guidelines. Two proposed updates are the Expected Moments Algorithm (EMA) to accommodate historical and censored data, and a generalized multiple Grubbs-Beck (MGB) low-outlier test. The current guidelines use a standard Grubbs-Beck (GB) method to identify low outliers, changing the determination of the moment estimators because B17B uses a conditional probability adjustment to handle low outliers while EMA censors the low outliers. B17B and EMA estimates are identical if no historical information or censored or low outliers are present in the peak-flow data. EMA with MGB (EMA-MGB) test was compared to the standard B17B (B17B-GB) method for flood frequency analysis at 328 streamgaging stations in Arizona. The methods were compared using the relative percent difference (RPD) between annual exceedance probabilities (AEPs), goodness-of-fit assessments, random resampling procedures, and Monte Carlo simulations. The AEPs were calculated and compared using both station skew and weighted skew. Streamgaging stations were classified by U.S. Geological Survey (USGS) National Water Information System (NWIS) qualification codes, used to denote historical and censored peak-flow data, to better understand the effect that nonstandard flood information has on the flood frequency analysis for each method. Streamgaging stations were also grouped according to geographic flood regions and analyzed separately to better understand regional differences caused by physiography and climate. The B

  12. Electrophysiological precursors of social conformity

    Science.gov (United States)

    Rieskamp, Jörg; Tugin, Sergey; Ossadtchi, Alexey; Krutitskaya, Janina; Klucharev, Vasily

    2013-01-01

    Humans often change their beliefs or behavior due to the behavior or opinions of others. This study explored, with the use of human event-related potentials (ERPs), whether social conformity is based on a general performance-monitoring mechanism. We tested the hypothesis that conflicts with a normative group opinion evoke a feedback-related negativity (FRN) often associated with performance monitoring and subsequent adjustment of behavior. The experimental results show that individual judgments of facial attractiveness were adjusted in line with a normative group opinion. A mismatch between individual and group opinions triggered a frontocentral negative deflection with the maximum at 200 ms, similar to FRN. Overall, a conflict with a normative group opinion triggered a cascade of neuronal responses: from an earlier FRN response reflecting a conflict with the normative opinion to a later ERP component (peaking at 380 ms) reflecting a conforming behavioral adjustment. These results add to the growing literature on neuronal mechanisms of social influence by disentangling the conflict-monitoring signal in response to the perceived violation of social norms and the neural signal of a conforming behavioral adjustment. PMID:22683703

  13. Valve stem packing seal test results for primary heat transport system conditions in Canadian nuclear generating stations

    International Nuclear Information System (INIS)

    Dixon, D.F.; Farrell, J.M.; Coutinho, R.F.

    1978-06-01

    Valve stem packing tests were done to obtain performance data on packing already in CANDU-PHW reactor service and on alternative packings. Most of the tests were replicated. Results are presented for ten packings tested under two stem cycle modes; leakage, packing consolidation and packing friction were the main responses. Packing tests were performed with water at close to CANDU-PHW reactor primary heat transport (PHT) system conditions (288 deg C and 10 MPa), but without ionizing radiation. The test rigs had rising, rotating stems. Stuffing box dimensions were typical of a standard Velan valve; packings were spring loaded to control applied packing stress

  14. Station Capacity

    DEFF Research Database (Denmark)

    Landex, Alex

    2011-01-01

    the probability of conflicts and the minimum headway times into account. The last method analyzes how optimal platform tracks are used by examining the arrival and departure pattern of the trains. The developed methods can either be used separately to analyze specific characteristics of the capacity of a station......Stations are often limiting the capacity of railway networks. This is due to extra need of tracks when trains stand still, trains turning around, and conflicting train routes. Although stations are often the capacity bottlenecks, most capacity analysis methods focus on open line capacity. Therefore...... for platform tracks and the probability that arriving trains will not get a platform track immediately at arrival. The third method is a scalable method that analyzes the conflicts in the switch zone(s). In its simplest stage, the method just analyzes the track layout while the more advanced stages also take...

  15. Shippingport Station Decommissioning Project

    International Nuclear Information System (INIS)

    McKernan, M.L.

    1989-01-01

    The Shippingport Atomic Power Station was located on the Ohio River in Shippingport Borough (Beaver County), Pennsylvania, USA. The US Atomic Energy Commission (AEC) constructed the plant in the mid-1950s on a seven and half acre parcel of land leased from Duquesne Light Company (DLC). The purposes were to demonstrate and to develop Pressurized Water Recovery technology and to generate electricity. DLC operated the Shippingport plant under supervision of (the successor to AEC) the Department of Energy (DOE)-Naval Reactors (NR) until operations were terminated on October 1, 1982. NR concluded end-of-life testing and defueling in 1984 and transferred the Station's responsibility to DOE Richland Operations Office (RL), Surplus Facility Management Program Office (SFMPO5) on September 5, 1984. SFMPO subsequently established the Shippingport Station Decommissioning Project and selected General Electric (GE) as the Decommissioning Operations Contractor. This report is intended to provide an overview of the Shippingport Station Decommissioning Project

  16. Electrophysiological Monitoring in Patients With Tumors of the Skull Base Treated by Carbon-12 Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Carozzo, Simone [Department of Neuroscience, Ophthalmology, and Genetics, University of Genova, Genova (Italy); Schardt, Dieter [Department of Biophysics, GSI Helmholtzzentrum für Schwerionenforschung, Darmstadt (Germany); Narici, Livio [Department of Physics, University of Rome Tor Vergata, Rome (Italy); Combs, Stephanie E.; Debus, Jürgen [Department of Radiation Oncology, University of Heidelberg, Heidelberg (Germany); Sannita, Walter G., E-mail: wgs@dism.unige.it [Department of Neuroscience, Ophthalmology, and Genetics, University of Genova, Genova (Italy); Department of Psychiatry, State University of New York, Stony Brook, New York (United States)

    2013-03-15

    Purpose: To report the results of short-term electrophysiologic monitoring of patients undergoing {sup 12}C therapy for the treatment of skull chordomas and chondrosarcomas unsuitable for radical surgery. Methods and Materials: Conventional electroencephalogram (EEG) and retinal and cortical electrophysiologic responses to contrast stimuli were recorded from 30 patients undergoing carbon ion radiation therapy, within a few hours before the first treatment and after completion of therapy. Methodologies and procedures were compliant with the guidelines of the International Federation for Clinical Neurophysiology and International Society for Clinical Electrophysiology of Vision. Results: At baseline, clinical signs were reported in 56.6% of subjects. Electrophysiologic test results were abnormal in 76.7% (EEG), 78.6% (cortical evoked potentials), and 92.8% (electroretinogram) of cases, without correlation with neurologic signs, tumor location, or therapy plan. Results on EEG, but not electroretinograms and cortical responses, were more often abnormal in patients with reported clinical signs. Abnormal EEG results and retinal/cortical responses improved after therapy in 40% (EEG), 62.5% (cortical potentials), and 70% (electroretinogram) of cases. Results on EEG worsened after therapy in one-third of patients whose recordings were normal at baseline. Conclusions: The percentages of subjects whose EEG results improved or worsened after therapy and the improvement of retinal/cortical responses in the majority of patients are indicative of a limited or negligible (and possibly transient) acute central nervous system toxicity of carbon ion therapy, with a significant beneficial effect on the visual pathways. Research on large samples would validate electrophysiologic procedures as a possible independent test for central nervous system toxicity and allow investigation of the correlation with clinical signs; repeated testing over time after therapy would demonstrate, and may

  17. The J-resistance curve Leak-before-Break test program on material for the Darlington Nuclear Generating Station

    International Nuclear Information System (INIS)

    Mukherjee, B.

    1988-01-01

    The Darlington Leak-Before-Break (DLBB) approach has been developed for large diameter (21, 22, 24 inch) SA106B heat transport (HT) piping and SA105 fittings as a design alternative to pipewhip restraints and in recognition of the questionable benefits of providing such restraints. Ontario Hydro's DLBB approach is based on the elastic plastic fracture mechanics method. In this test program, J-resistance curves were determined from actual pipe heats that were used in the construction of the Darlington heat transport systems (Units 1 and 2). Test blocks were prepared using four different welding procedures for nuclear Class I piping. The test program was designed to take into account the effect of various factors such as test temperature, crack plane orientation, welding effects, etc., which have influence on fracture properties. A total of 91 tests were conducted. An acceptable lower bound J-resistance curve for the piping steels was obtained by machining maximum thickness specimens from the pipes and by testing side grooved compact tension specimens. Test results showed that all pipes, welds and heat-affected zone materials within the scope of the DLBB program exhibited uppershelf toughness behaviour. All specimens showed high crack initiation toughness Jsub(lc), rising J-resistance curve and stable and ductile crack extension. Toughness of product forms depended on the direction of crack extension (circumferential versus axial crack orientation). Toughness of DLBB welds and parent materials at 250 0 C was lower than that at 20 0 C. (author)

  18. Optimizing Nanoelectrode Arrays for Scalable Intracellular Electrophysiology.

    Science.gov (United States)

    Abbott, Jeffrey; Ye, Tianyang; Ham, Donhee; Park, Hongkun

    2018-03-20

    Electrode technology for electrophysiology has a long history of innovation, with some decisive steps including the development of the voltage-clamp measurement technique by Hodgkin and Huxley in the 1940s and the invention of the patch clamp electrode by Neher and Sakmann in the 1970s. The high-precision intracellular recording enabled by the patch clamp electrode has since been a gold standard in studying the fundamental cellular processes underlying the electrical activities of neurons and other excitable cells. One logical next step would then be to parallelize these intracellular electrodes, since simultaneous intracellular recording from a large number of cells will benefit the study of complex neuronal networks and will increase the throughput of electrophysiological screening from basic neurobiology laboratories to the pharmaceutical industry. Patch clamp electrodes, however, are not built for parallelization; as for now, only ∼10 patch measurements in parallel are possible. It has long been envisioned that nanoscale electrodes may help meet this challenge. First, nanoscale electrodes were shown to enable intracellular access. Second, because their size scale is within the normal reach of the standard top-down fabrication, the nanoelectrodes can be scaled into a large array for parallelization. Third, such a nanoelectrode array can be monolithically integrated with complementary metal-oxide semiconductor (CMOS) electronics to facilitate the large array operation and the recording of the signals from a massive number of cells. These are some of the central ideas that have motivated the research activity into nanoelectrode electrophysiology, and these past years have seen fruitful developments. This Account aims to synthesize these findings so as to provide a useful reference. Summing up from the recent studies, we will first elucidate the morphology and associated electrical properties of the interface between a nanoelectrode and a cellular membrane

  19. Normal Values for Heart Electrophysiology Parameters of Healthy Swine Determined on Electrophysiology Study.

    Science.gov (United States)

    Noszczyk-Nowak, Agnieszka; Cepiel, Alicja; Janiszewski, Adrian; Pasławski, Robert; Gajek, Jacek; Pasławska, Urszula; Nicpoń, Józef

    2016-01-01

    Swine are a well-recognized animal model for human cardiovascular diseases. Despite the widespread use of porcine model in experimental electrophysiology, still no reference values for intracardiac electrical activity and conduction parameters determined during an invasive electrophysiology study (EPS) have been developed in this species thus far. The aim of the study was to develop a set of normal values for intracardiac electrical activity and conduction parameters determined during an invasive EPS of swine. The study included 36 healthy domestic swine (24-40 kg body weight). EPS was performed under a general anesthesia with midazolam, propofol and isoflurane. The reference values for intracardiac electrical activity and conduction parameters were calculated as arithmetic means ± 2 standard deviations. The reference values were determined for AH, HV and PA intervals, interatrial conduction time at its own and imposed rhythm, sinus node recovery time (SNRT), corrected sinus node recovery time (CSNRT), anterograde and retrograde Wenckebach points, atrial, atrioventricular node and ventricular refractory periods. No significant correlations were found between body weight and heart rate of the examined pigs and their electrophysiological parameters. The hereby presented reference values can be helpful in comparing the results of various studies, as well as in more accurately estimating the values of electrophysiological parameters that can be expected in a given experiment.

  20. Clinical and electrophysiological aspects of tics in children.

    Science.gov (United States)

    Safiullina, G I; Safiullina, A A

    2015-01-01

    Tics are diverse in nature inappropriate movements or vocalizations. They significantly degrade patients' quality of life, lead to social difficulties, and disturbance of learning especially during exacerbations. The prevalence of tics among children ranges from 4% to 24%, thus emphasizing the relevance of the problem. To study clinical and electrophysiological features of tics in children with development of new treatment methods. We conducted a comprehensive clinical and electrophysiological examination of 50 patients with tics, aged 5 to 15 years. The control group consisted of 20 healthy children. The research included a thorough study of the history, neurological examination, manual testing of skeletal muscles, psychological testing. Electrophysiological examination included a review of the functional state of corticospinal tract (CST) by the method of magnetic stimulation (MS), study of polysynaptic reflex excitability (PRE) according to a late component of the blink reflex (BR). Statistical analysis included parametric and nonparametric methods of data processing. All children of the study group showed signs of minimal brain dysfunction (MBD), they had complicated antenatal and postnatal history (trauma, disease, occurring with intoxication). There was a trend towards the increase of MBD signs with worsening of tics. Manual diagnosis in patients identified functional blockade at different levels of the vertebral column, sacroiliac joints, we identified latent myofascial trigger points (MFTP) mainly in the cervical-collar zone, in the area of the paravertebral muscles, periosteal triggers in the area of the sacroiliac joints.The research allowed determining decrease in propagation velocity of excitation (PVE) throughout CST in patients with tics. Correlation analysis revealed a negative correlation between the severity of tics and PVE (r = -0.38; p tics: I - low and moderate type of reflex responses; and II - high type of reflex responses. Collation of data

  1. Microbial Challenge Testing of Single Liquid Cathode Feed Water Electrolysis Cells for the International Space Station (ISS) Oxygen Generator Assembly (OGA)

    Science.gov (United States)

    Roy, Robert J.; Wilson, Mark E.; Diderich, Greg S.; Steele, John W.

    2011-01-01

    The International Space Station (ISS) Oxygen Generator Assembly (OGA) operational performance may be adversely impacted by microbiological growth and biofilm formation over the electrolysis cell membranes. Biofilms could hinder the transport of water from the bulk fluid stream to the membranes and increase the cell concentration overpotential resulting in higher cell voltages and a shorter cell life. A microbial challenge test was performed on duplicate single liquid-cathode feed water electrolysis cells to evaluate operational performance with increasing levels of a mixture of five bacteria isolated from ISS and Space Shuttle potable water systems. Baseline performance of the single water electrolysis cells was determined for approximately one month with deionized water. Monthly performance was also determined following each inoculation of the feed tank with 100, 1000, 10,000 and 100,000 cells/ml of the mixed suspension of test bacteria. Water samples from the feed tank and recirculating water loops for each cell were periodically analyzed for enumeration and speciation of bacteria and total organic carbon. While initially a concern, this test program has demonstrated that the performance of the electrolysis cell is not adversely impacted by feed water containing the five species of bacteria tested at a concentration measured as high as 1,000,000 colony forming units (CFU)/ml. This paper presents the methodologies used in the conduct of this test program along with the performance test results at each level of bacteria concentration.

  2. Electrophysiology of Extraocular Cranial Nerves: Oculomotor, Trochlear, and Abducens Nerve.

    Science.gov (United States)

    Hariharan, Praveen; Balzer, Jeffery R; Anetakis, Katherine; Crammond, Donald J; Thirumala, Parthasarathy D

    2018-01-01

    The utility of extraocular cranial nerve electrophysiologic recordings lies primarily in the operating room during skull base surgeries. Surgical manipulation during skull base surgeries poses a risk of injury to multiple cranial nerves, including those innervating extraocular muscles. Because tumors distort normal anatomic relationships, it becomes particularly challenging to identify cranial nerve structures. Studies have reported the benefits of using intraoperative spontaneous electromyographic recordings and compound muscle action potentials evoked by electrical stimulation in preventing postoperative neurologic deficits. Apart from surgical applications, electromyography of extraocular muscles has also been used to guide botulinum toxin injections in patients with strabismus and as an adjuvant diagnostic test in myasthenia gravis. In this article, we briefly review the rationale, current available techniques to monitor extraocular cranial nerves, technical difficulties, clinical and surgical applications, as well as future directions for research.

  3. Small zeolite column tests for removal of cesium from high radioactive contaminated water in Fukushima Daiichi Nuclear Power Station

    International Nuclear Information System (INIS)

    Hijikata, Takatoshi; Uozumi, Koichi; Tukada, Takeshi; Koyama, Tadafumi; Ishikawa, Keiji; Ono, Shoichi; Suzuki, Shunichi; Denton, Mark; Raymont, John

    2011-01-01

    After the earthquake on March 11th 2011, a large amount (more than 0.12 million m 3 ) of highly radioactive contaminated water had pooled in Fukushima Daiichi nuclear power station. As an urgent issue, highly radioactive nuclides should be removed from this contaminated water to reduce radioactivity in the turbine buildings and nuclear reactor buildings. Removal of Cs from this contaminated water is a key issue, because 134 Cs and 137 Cs are highly radioactive γ-emitting nuclides. The zeolite column system was used for Cs and Sr removal from the radioactive water of Three-Mile Island Unit 2, and modified columns were then developed as a Cs removal method for high-level radioactive water in US national laboratories (WRSC, ORNL, PNNL, Hanford, etc.). In order to treat Fukushima's highly contaminated water with a similar system, it was necessary to understand the properties of zeolite to remove Cs from sea salt as well as the applicability of the column system to a high throughput of around 1200 m 3 /d. The kinetic characteristics of the column were another property to be understood before actual operation. Hence, a functional small-scale zeolite column system was installed in CRIEPI for conducting the experiments to understand decontamination behaviors. Each column has a 2- or 3-cm inner diameter and a 12-cm height, and 12 g of zeolite-type media was packed into the column. The column experiments were carried out with Kurion-zeolite, Herschelite, at different feed rates of simulated water with different concentrations of Cs and sea salt. As for the water with 4 ppm Cs and 0 ppm sea salt, only a 10% Cs concentration was observed in the effluent after 20,000 bed volumes were fed at a rate of 33 cm/min, which corresponds to the actual system. On the other hand, a 40% Cs concentration was observed in the effluent after only 50 bed volumes were passed for water with 2 ppm Cs and 3.4 wt.% sea salt at a feed rate of 34 cm/min. As the absorption of Cs is hampered by the

  4. Ultraconformable Temporary Tattoo Electrodes for Electrophysiology

    Science.gov (United States)

    Ferrari, Laura M.; Sudha, Sudha; Tarantino, Sergio; Esposti, Roberto; Bolzoni, Francesco; Cavallari, Paolo; Cipriani, Christian

    2018-01-01

    Abstract Electrically interfacing the skin for monitoring personal health condition is the basis of skin‐contact electrophysiology. In the clinical practice the use of stiff and bulky pregelled or dry electrodes, in contrast to the soft body tissues, imposes severe restrictions to user comfort and mobility while limiting clinical applications. Here, in this work dry, unperceivable temporary tattoo electrodes are presented. Customized single or multielectrode arrays are readily fabricated by inkjet printing of conducting polymer onto commercial decal transfer paper, which allows for easy transfer on the user's skin. Conformal adhesion to the skin is provided thanks to their ultralow thickness (Tattoo electrode–skin contact impedance is characterized on short‐ (1 h) and long‐term (48 h) and compared with standard pregelled and dry electrodes. The viability in electrophysiology is validated by surface electromyography and electrocardiography recordings on various locations on limbs and face. A novel concept of tattoo as perforable skin‐contact electrode, through which hairs can grow, is demonstrated, thus permitting to envision very long‐term recordings on areas with high hair density. The proposed materials and patterning strategy make this technology amenable for large‐scale production of low‐cost sensing devices. PMID:29593975

  5. Electrophysiological studies in healthy subjects involving caffeine.

    Science.gov (United States)

    de Carvalho, Mamede; Marcelino, Erica; de Mendonça, Alexandre

    2010-01-01

    We review the electrophysiological studies concerning the effects of caffeine on muscle, lower and upper motor neuron excitability and cognition. Several different methods have been used, such as electromyography, recruitment analysis, H-reflex, transcranial magnetic stimulation (TMS), electroencephalography and event-related potentials. The positive effect of caffeine on vigilance, attention, speed of reaction, information processing and arousal is supported by a number of electrophysiological studies. The evidence in favor of an increased muscle fiber resistance is not definitive, but higher or lower motor neuron excitability can occur as a consequence of a greater excitation of the descending input from the brainstem and upper motor neurons. TMS can address the influence of caffeine on the upper motor neuron. Previous studies showed that cortico-motor threshold and intracortical excitatory and inhibitory pathways are not influenced by caffeine. Nonetheless, our results indicate that cortical silent period (CSP) is reduced in resting muscles after caffeine consumption, when stimulating the motor cortex with intensities slightly above threshold. We present new data demonstrating that this effect is also observed in fatigued muscle. We conclude that CSP can be considered a surrogate marker of the effect of caffeine in the brain, in particular of its central ergogenic effect.

  6. Validation of long-range scanning lidars deployed around the Høvsøre Test Station

    DEFF Research Database (Denmark)

    Lea, Guillaume; Courtney, Michael

    This report describes validation tests performed on the long-range scanning lidars prior to deployment in the RUNE campaign. Position and speed accuracy tests have been performed at a range of 5km from the Høvsøre met mast. This range is typical of ranges for near-coastal resource measurements....... The accuracy of the beam positioning was checked by comparing the predicted position to the position found from hard-target returns from the mast. Radial speeds measured by the lidar were also found to be in close agreement with the mast measured wind speeds projected in the line of sight direction....

  7. Method of 16N generation for test of radiation controlled channels at nuclear power stations with water-cooled reactors

    International Nuclear Information System (INIS)

    Khryachkov, V.A.; Bondarenko, I.P.; Dvornikov, P.A.; Zhuravlev, B.V.; Kovtun, S.N.; Khromyleva, T.A.; Pavlov, A.V.; Roshchin, N.G.

    2012-01-01

    The preferences of nuclear reaction use for radiation control channels test in water-cooled power reactors have been analyzed in the paper. The new measurements for more accurate determination of reaction cross section energy dependence have been carried out. A set of new methods for background reducing and improvement of events determination reliability has also been developed [ru

  8. The Cyborg Astrobiologist: testing a novelty detection algorithm on two mobile exploration systems at Rivas Vaciamadrid in Spain and at the Mars Desert Research Station in Utah

    Science.gov (United States)

    McGuire, P. C.; Gross, C.; Wendt, L.; Bonnici, A.; Souza-Egipsy, V.; Ormö, J.; Díaz-Martínez, E.; Foing, B. H.; Bose, R.; Walter, S.; Oesker, M.; Ontrup, J.; Haschke, R.; Ritter, H.

    2010-01-01

    In previous work, a platform was developed for testing computer-vision algorithms for robotic planetary exploration. This platform consisted of a digital video camera connected to a wearable computer for real-time processing of images at geological and astrobiological field sites. The real-time processing included image segmentation and the generation of interest points based upon uncommonness in the segmentation maps. Also in previous work, this platform for testing computer-vision algorithms has been ported to a more ergonomic alternative platform, consisting of a phone camera connected via the Global System for Mobile Communications (GSM) network to a remote-server computer. The wearable-computer platform has been tested at geological and astrobiological field sites in Spain (Rivas Vaciamadrid and Riba de Santiuste), and the phone camera has been tested at a geological field site in Malta. In this work, we (i) apply a Hopfield neural-network algorithm for novelty detection based upon colour, (ii) integrate a field-capable digital microscope on the wearable computer platform, (iii) test this novelty detection with the digital microscope at Rivas Vaciamadrid, (iv) develop a Bluetooth communication mode for the phone-camera platform, in order to allow access to a mobile processing computer at the field sites, and (v) test the novelty detection on the Bluetooth-enabled phone camera connected to a netbook computer at the Mars Desert Research Station in Utah. This systems engineering and field testing have together allowed us to develop a real-time computer-vision system that is capable, for example, of identifying lichens as novel within a series of images acquired in semi-arid desert environments. We acquired sequences of images of geologic outcrops in Utah and Spain consisting of various rock types and colours to test this algorithm. The algorithm robustly recognized previously observed units by their colour, while requiring only a single image or a few images to

  9. Ultimate storage of spent fuel elements of the AVR test power station in the Asse salt mine

    International Nuclear Information System (INIS)

    Wolf, J.

    1975-02-01

    With regard to the ultimate storage of irradiated AVR pebble-bed reactor carbide fuel elements in the saline of Asse, a number of tests and calculations are presented to demonstrate that there is no credible possibility of the MCA (maximum credible accident) defined for the saline. The safety of persons is not threatened during the operation of spent fuel storage nor at any later time (extrapolation up to approx. 1,000 years after storage). 1,000 fuel elements at a time are packed up in gas-tight containers which are stacked in boreholes. The boreholes are then sealed with concrete. Lay-out and functions of the special airlock and transportation systems - from the packing of the containers in a hot cell to the final storage in the borehole - are described with special reference to aspects of the safety of the overall procedure. The possible accidents in the mine are discussed in detail. 85 Kr and T release rates are determined in laboratory tests by heating of the spherical fuel elements. Tests with fuel elements embedded in salt or stagnant brine were carried out at varies temperatures to investigate their behaviour in final storage. Kr and T release, extraction of fission products, mechanical resistance and corrosion were examined in these tests. Finally, the permeability of salt and salt concrete to radioactive gases were investigated in a special experimental arrangement. The diffusion and permeability coefficients obtained for 85 Kr, HT and HTO allow an estimation of the gas discharge of the stored fuel element. (RB/AK) [de

  10. Structural integrity test of Indian PHWR containment of Kaiga- 1 and 2 and RAPS- 3 and 4 atomic power stations

    International Nuclear Information System (INIS)

    Samota, Arun; Verma, U.S.P.; Warudkar, A.S.; Mohan, Nalini; Bhawal, R.N.; Bajaj, S.S.

    2002-01-01

    Full text: The structural integrity tests of Kaiga 1, 2 and RAPS 3, 4 primary containment were carried out as per requirements specified in RCC-G code by pressurizing the containment with oil free air at design pressure of 1.73 Kg/cm 2 (g). Dilations were monitored in vertical and radial directions by installing dial gauges at various locations on the outer surface of primary containment. The dilations were generally observed to be linear with the pressure and the residual displacements were within the acceptable limit. Strains were measured in meridional and circumferential directions at different pressure levels by using a large number of different types of strain gauge. While the behaviour of embedded type vibrating wire strain gauges was excellent, the behaviour of surface mounted electrical resistance (SMER) was satisfactory. Other parameters monitored were crack, differential and absolute settlements. No crack was noticed in any of the containment. No absolute and differential settlements were noticed. The results of the tests have demonstrated elastic behaviour of the containment. The acceptance criteria of the tests were met with good margin

  11. Power stations

    International Nuclear Information System (INIS)

    Cawte, H.; Philpott, E.F.

    1980-01-01

    The object is to provide a method of operating a dual purpose power station so that the steam supply system is operated at a high load factor. The available steam not required for electricity generation is used to provide process heat and the new feature is that the process plant capacity is determined to make the most economic use of the steam supply system, and not to match the passout capacity of the turbine of the turbogenerator. The product of the process plant should, therefore, be capable of being stored. A dual-purpose power station with a nuclear-powered steam source, turbogenerating means connected to the steam source and steam-powered process plant susceptible to wide variation in its rate of operation is described. (U.K.)

  12. Confirmation test on the dynamic interaction between a model reactor-building foundation and ground in the Sendai Nuclear Power Station

    International Nuclear Information System (INIS)

    Umezu, Hideo; Kisaki, Noboru; Shiota, Mutsumi

    1982-01-01

    On the site of unit 2 (planned) in the Sendai Nuclear Power Station, a model reactor-building foundation of reinforced concrete with diameter of 12 m and height of 5 m was installed. With a vibration generator, its forced vibration tests were carried out in October to December, 1980. Valuable data were able to be obtained on the dynamic interaction between the model foundation and the ground, and also the outlook for the application of theories in hard base rock was obtained. (1) The resonance frequency of the model foundation in horizontal vibration was 35 Hz in both NS and EW directions. (2) Remarkable difference was not observed in the horizontal vibration behavior between NS and EW directions, so that there is not anisotropy in the ground. (3) The model foundation was deformed nearly as a rigid body. (J.P.N.)

  13. Study of the mechanical properties of the electric power station components: the punch test; Etude des proprietes mecaniques des composants de centrales thermiques: l'essai punch test

    Energy Technology Data Exchange (ETDEWEB)

    Isselin, J

    2003-03-15

    The aging of the electric production park implies an increasing need of knowledge concerning the evolution of the mechanical properties of its components. With regard to this problem, the availability in material is more and more small. This work proposes to characterize these properties through a mechanical test called Punch test. The main characteristic of this test is to use very small volume samples. The development of this test has been carried out by the study of a 15 MDV 4-05 steel coming from a steam drum of a thermal power plant after 145000 hours of service. At first, we have measured the influence of the parameters of this test. Then, the study has dealt more particularly on the transition temperature of the material. With the finite element simulation method, the strain hardening coefficient of the material has been determined. (O.M.)

  14. Uranium from Seawater Marine Testing Program at the University of Miami’s Broad Key Island Research Station

    Energy Technology Data Exchange (ETDEWEB)

    Gill, Gary A. [Pacific Northwest National Lab. (PNNL), Sequim, WA (United States). Marine Sciences Lab.; Kuo, Li-Jung [Pacific Northwest National Lab. (PNNL), Sequim, WA (United States). Marine Sciences Lab.; Strivens, Jonathan E. [Pacific Northwest National Lab. (PNNL), Sequim, WA (United States). Marine Sciences Lab.; Wood, Jordana R. [Pacific Northwest National Lab. (PNNL), Sequim, WA (United States). Marine Sciences Lab.; Schlafer, Nicholas J. [Pacific Northwest National Lab. (PNNL), Sequim, WA (United States). Marine Sciences Lab.; D' Alessandro, Evan [Univ. of Miami, FL (United States). Rosensteil School of Marine and Atmospheric Sciences

    2016-09-30

    Marine testing at Broad Key Island (BKI), Florida was conducted to validate adsorption capacity and adsorption kinetics results obtained for several formulations of the ORNL amidoxime-based polymeric adsorbents in Sequim Bay, Washington in another location with different oceanographic and water quality conditions (e.g. temperature, dissolved organic carbon, salinity and trace element content). Broad Key is a small island off the southeast coast of Florida at the southern end of Biscayne Bay. Flow-through column and recirculating flume experiments were conducted at BKI using ambient filtered seawater and identical exposure systems as were used at the Pacific Northwest National Laboratory’s (PNNL) Marine Sciences laboratory (MSL). Testing was conducted in two periods in FY 2015 and FY 2016 with five different amidoxime-based adsorbent materials, four produced by ORNL (AF1, AI8, AF8, and AF1-DMSO) and one by LCW technologies (LCW-10). All exposures were conducted at ambient seawater temperatures, with moderate temperature control on the ambient seawater to mitigate large daily swings in the seawater temperature. The ORNL adsorbents AF1, AI8 and AF1-AO-DMSO all had fairly similar adsorption capacities (6.0 to 6.6 g U/ kg adsorbent) after 56 days of exposure at ambient temperature (26 to 31 °C) and salinity (35.7 to 37.4), but the AF8 adsorbent was considerably lower at 4.4 g U/kg adsorbent. All the adsorbents tested at BKI had higher capacities than was observed at PNNL, with the higher temperatures likely a major factor contributing to this difference. In general, the elemental distribution (expressed as a relative percentage) on all the adsorbents agreed well, including good agreement with the elemental distribution pattern for AF1 adsorbent exposed at PNNL. The most notable exception to a uniform elemental distributional pattern across the various adsorbents occurs with vanadium. The relative mass percentage for vanadium retained by the adsorbents ranged from a

  15. The development of future-oriented control: an electrophysiological investigation.

    Science.gov (United States)

    Waxer, Matthew; Morton, J Bruce

    2011-06-01

    Cognitive control, or the ability to focus attention and select task-appropriate responses, is not static but can be dynamically adjusted in the face of changing environmental circumstances. Several models suggest a role for conflict-monitoring in triggering these adjustments, whereby instances of response uncertainty are detected by the anterior cingulate cortex and strengthen attention-guiding rules actively maintained by lateral prefrontal cortex. Given the continued development of active maintenance mechanisms into adolescence, these models predict that the capacity to dynamically modulate control should be protracted in its development. The present study tested this prediction by examining age-related differences in behavioral and electrophysiological adaptations to prior conflict. Children, adolescents, and adults were administered the Dimensional Change Card Sort (DCCS; Zelazo, 2006) - a developmentally-appropriate task modified so that response conflict varied from trial to trial - as cortical activity was measured by means of event-related potentials (ERPs). Although all groups showed a robust conflict effect, there were pronounced age-related differences in behavioral and electrophysiological adaptations to prior conflict. First, responses to incongruent trials were faster following incongruent trials than following congruent trials, but only for adults and adolescents. Second, ERP components that indexed response conflict, and the cortical source of these components, were modulated by preceding conflict for adults and adolescents, but not children. Taken together, the findings suggest that adults and adolescents take advantage of prior conflict to prepare for the future, whereas children respond to cognitive challenges as they occur. Theoretical implications are discussed. Copyright © 2011 Elsevier Inc. All rights reserved.

  16. Simple Ion Channels: From Structure to Electrophysiology and Back

    Science.gov (United States)

    Pohorille, Andrzej

    2018-01-01

    A reliable way to establish whether our understanding of a channel is satisfactory is to reproduce its measured ionic conductance over a broad range of applied voltages in computer simulations. In molecular dynamics (MD), this can be done by way of applying an external electric field to the system and counting the number of ions that traverse the channel per unit time. Since this approach is computationally very expensive, we have developed a markedly more efficient alternative in which MD is combined with the electrodiffusion (ED) equation. In this approach, the assumptions of the ED equation can be rigorously tested, and the precision and consistency of the calculated conductance can be determined. We have demonstrated that the full current/voltage dependence and the underlying free energy profile for a simple channel can be reliably calculated from equilibrium or non-equilibrium MD simulations at a single voltage. To carry out MD simulations, a structural model of a channel has to be assumed, which is an important constraint, considering that high-resolution structures are available for only very few simple channels. If the comparison of calculated ionic conductance with electrophysiological data is satisfactory, it greatly increases our confidence that the structure and the function are described sufficiently accurately. We examined the validity of the ED for several channels embedded in phospholipid membranes - four naturally occurring channels: trichotoxin, alamethicin, p7 from hepatitis C virus (HCV) and Vpu from the HIV-1 virus, and a synthetic, hexameric channel, formed by a 21-residue peptide that contains only leucine and serine. All these channels mediate transport of potassium and chloride ions. It was found that the ED equation is satisfactory for these systems. In some of them experimental and calculated electrophysiological properties are in good agreement, whereas in others there are strong indications that the structural models are incorrect.

  17. Development of Flow Boiling and Condensation Experiment on the International Space Station- Normal and Low Gravity Flow Boiling Experiment Development and Test Results

    Science.gov (United States)

    Nahra, Henry K.; Hall, Nancy R.; Hasan, Mohammad M.; Wagner, James D.; May, Rochelle L.; Mackey, Jeffrey R.; Kolacz, John S.; Butcher, Robert L.; Frankenfield, Bruce J.; Mudawar, Issam; hide

    2013-01-01

    Flow boiling and condensation have been identified as two key mechanisms for heat transport that are vital for achieving weight and volume reduction as well as performance enhancement in future space systems. Since inertia driven flows are demanding on power usage, lower flows are desirable. However, in microgravity, lower flows are dominated by forces other than inertia (like the capillary force). It is of paramount interest to investigate limits of low flows beyond which the flow is inertial enough to be gravity independent. One of the objectives of the Flow Boiling and Condensation Flight Experiment sets to investigate these limits for flow boiling and condensation. A two-phase flow loop consisting of a Flow Boiling Module and two Condensation Modules has been developed to experimentally study flow boiling condensation heat transfer in the reduced gravity environment provided by the reduced gravity platform. This effort supports the development of a flow boiling and condensation facility for the International Space Station (ISS). The closed loop test facility is designed to deliver the test fluid, FC-72 to the inlet of any one of the test modules at specified thermodynamic and flow conditions. The zero-g-aircraft tests will provide subcooled and saturated flow boiling critical heat flux and flow condensation heat transfer data over wide range of flow velocities. Additionally, these tests will verify the performance of all gravity sensitive components, such as evaporator, condenser and accumulator associated with the two-phase flow loop. We will present in this paper the breadboard development and testing results which consist of detailed performance evaluation of the heater and condenser combination in reduced and normal gravity. We will also present the design of the reduced gravity aircraft rack and the results of the ground flow boiling heat transfer testing performed with the Flow Boiling Module that is designed to investigate flow boiling heat transfer and

  18. Industrial test and techno-economic analysis of CO2 capture in Huaneng Beijing coal-fired power station

    International Nuclear Information System (INIS)

    Huang, Bin; Xu, Shisen; Gao, Shiwang; Liu, Lianbo; Tao, Jiye; Niu, Hongwei; Cai, Ming; Cheng, Jian

    2010-01-01

    The first industrial-scale CO 2 capture plant in China has been demonstrated at Huaneng Beijing power plant has shown that this technology is a good option for the capture of CO 2 produced by commercial coal-fired power plants. The commissioning and industrial tests are introduced in this paper. The tests show that in the early stages of the passivation phase, the concentration variations of amine, anti-oxidant and Fe 3+ are in the normal range, and the main parameters achieve the design value. The efficiency of the CO 2 capture was about 80-85%, and by the end of January 2009 about 900 tons of CO 2 (99.7%) have been captured. The equipment investment and consumptive costs, including steam, power, solution and others, have been analyzed. The results show: the cost of the absorber and the stripper account for about 50% of main equipment; the consumptive cost is about 25.3 US$ per metric tons of CO 2 , of which the steam requirement accounts for about 55%; the COE increased by 0.02 US$/kW h and the electricity purchase price increased by 29%. (author)

  19. Subjective symptoms of carpal tunnel syndrome correlate more with psychological factors than electrophysiological severity

    Directory of Open Access Journals (Sweden)

    Firosh Khan

    2017-01-01

    Full Text Available Aim: Carpal tunnel syndrome (CTS is the most common entrapment neuropathy and is one of the most common requests for electrodiagnosis. We aimed to note the relationship of subjective symptom severity of CTS, with objective electrophysiological severity and psychological status of patients. Patients and Methods: One hundred and forty-four consecutive patients of CTS referred to neurophysiology laboratory of a tertiary care hospital over 1 year were prospectively studied. Boston CTS Assessment Questionnaire (BCTSAQ and visual analog scale (VAS were used to assess subjective symptom severity. Psychological status was assessed by Hospital Anxiety and Depression Scale (HADS. Electrophysiological severity of CTS was estimated by median motor distal latency and median to ulnar peak sensory latency difference across the wrist. Each parameter in both hands was scored from 0 to 3 depending on the severity grade, and a composite electrophysiological severity score (CEPSS was calculated for each patient by summing up the scores in both hands. Statistical analysis was done by Spearman's rank correlation test. Results: There was significant correlation of BCTSAQ with VAS (P = 0.001, HADS anxiety score (P < 0.001, and HADS depression score (P = 0.01. CEPSS had no significant correlation with VAS (P = 0.103, HADS anxiety score (P = 0.211, or HADS depression score (P = 0.55. CEPSS had a borderline correlation with BCTSAQ (P = 0.048. Conclusions: While the subjective symptoms of CTS are well correlated with psychological factors, their correlation with objective electrophysiological severity is weak. Hence, prompt treatment of psychological comorbidity is important in symptomatic management of CTS; decision about surgical intervention should be based on electrophysiological severity rather than symptom severity.

  20. Biofeedback in psychomotor training. Electrophysiological basis.

    Science.gov (United States)

    Bazanova, O M; Mernaya, E M; Shtark, M B

    2009-06-01

    The influences of individual musical practice and the same practice supplemented with biofeedback using electrophysiological markers for optimum music-performing activity were studied in 39 music students. Traditional technical practice produced increases in integral EMG power and decreases in alpha activity in most of the students with initially low maximum alpha activity peak frequencies. Similar practice but combined with individual sessions of alpha-EEG/EMG biofeedback were accompanied by increases in the frequency, bandwidth, and activation responses of EEG alpha rhythms in all subjects, along with decreases in EEG integral power. The efficacy of training with biofeedback and the ability to experience psychomotor learning depended on the initial individual characteristics of EEG alpha activity.

  1. [Biofeedback in psychomotor training. Electrophysiological bases].

    Science.gov (United States)

    Bazanova, O M; Mernaia, E M; Shtark, M B

    2008-05-01

    Comparison of influence of usual musical practice and the same trainings but using biofeedback on electrophysiological and psychological markers of optimal psychomotor functioning in 39 students-musicians revealed that the obvious musical practice caused psychomotor pressure in most students (with initially low individual alpha peak frequency), whereas similar practice combined with an individualized session of alpha-EEG/EMG biofeedback was accompanied by increase of alpha-activity in all examinees and a decrease (reduction) of integrated EMG that indicated reaching of optimal psychomotor functioning. It appears that the psychomotor learning ability depends on the baseline individual alpha-activity. Individual alpha peak frequency was associated with fluency and efficiency of psychomotor performance, individual alpha band width--with plasticity and creativity, individual amount of alpha suppression in response to opening eyes--with the level of selfactualization. These alpha activity EEG indices correlated with efficiency of the biofeedback training.

  2. Automatic Parameterization Strategy for Cardiac Electrophysiology Simulations.

    Science.gov (United States)

    Costa, Caroline Mendonca; Hoetzl, Elena; Rocha, Bernardo Martins; Prassl, Anton J; Plank, Gernot

    2013-10-01

    Driven by recent advances in medical imaging, image segmentation and numerical techniques, computer models of ventricular electrophysiology account for increasingly finer levels of anatomical and biophysical detail. However, considering the large number of model parameters involved parameterization poses a major challenge. A minimum requirement in combined experimental and modeling studies is to achieve good agreement in activation and repolarization sequences between model and experiment or patient data. In this study, we propose basic techniques which aid in determining bidomain parameters to match activation sequences. An iterative parameterization algorithm is implemented which determines appropriate bulk conductivities which yield prescribed velocities. In addition, a method is proposed for splitting the computed bulk conductivities into individual bidomain conductivities by prescribing anisotropy ratios.

  3. Lyme carditis. Electrophysiologic and histopathologic study

    International Nuclear Information System (INIS)

    Reznick, J.W.; Braunstein, D.B.; Walsh, R.L.; Smith, C.R.; Wolfson, P.M.; Gierke, L.W.; Gorelkin, L.; Chandler, F.W.

    1986-01-01

    To further define the nature of Lyme carditis, electrophysiologic study and endomyocardial biopsy were performed in a patient with Lyme disease, whose principal cardiac manifestation was high-degree atrioventricular block. Intracardiac recording demonstrated supra-Hisian block and complete absence of an escape mechanism. Gallium 67 scanning demonstrated myocardial uptake, and right ventricular endomyocardial biopsy revealed active lymphocytic myocarditis. A structure compatible with a spirochetal organism was demonstrated in one biopsy specimen. It is concluded that Lyme disease can produce active myocarditis, as suggested by gallium 67 imaging and confirmed by endomyocardial biopsy. Furthermore, the presence of high-grade atrioventricular block in this disease requires aggressive management with temporary pacemaker and corticosteroid therapy

  4. Examination of Communication Delays on Team Performance: Utilizing the International Space Station (ISS) as a Test Bed for Analog Research

    Science.gov (United States)

    Keeton, K. E.; Slack, K, J.; Schmidt, L. L.; Ploutz-Snyder, R.; Baskin, P.; Leveton, L. B.

    2011-01-01

    Operational conjectures about space exploration missions of the future indicate that space crews will need to be more autonomous from mission control and operate independently. This is in part due to the expectation that communication quality between the ground and exploration crews will be more limited and delayed. Because of potential adverse effects on communication quality, both researchers and operational training and engineering experts have suggested that communication delays and the impact these delays have on the quality of communications to the crew will create performance decrements if crews are not given adequate training and tools to support more autonomous operations. This presentation will provide an overview of a research study led by the Behavioral Health and Performance Element (BHP) of the NASA Human Research Program that examines the impact of implementing a communication delay on ISS on individual and team factors and outcomes, including performance and related perceptions of autonomy. The methodological design, data collection efforts, and initial results of this study to date will be discussed . The results will focus on completed missions, DRATS and NEEMO15. Lessons learned from implementing this study within analog environments will also be discussed. One lesson learned is that the complexities of garnishing a successful data collection campaign from these high fidelity analogs requires perseverance and a strong relationship with operational experts. Results of this study will provide a preliminary understanding of the impact of communication delays on individual and team performance as well as an insight into how teams perform and interact in a space-like environment . This will help prepare for implementation of communication delay tests on the ISS, targeted for Increment 35/36.

  5. Electrophysiological Evaluation of Dysphagia in the Mild or Moderate Patients with Multiple Sclerosis: A Concept of Subclinical Dysphagia.

    Science.gov (United States)

    Beckmann, Yesim; Gürgör, Nevin; Çakır, Ahmet; Arıcı, Şehnaz; İncesu, Tülay Kurt; Seçil, Yaprak; Ertekin, Cumhur

    2015-06-01

    Swallowing mechanism and neurogenic dysphagia in MS have been rarely studied by electromyographical (EMG) methods. This study aims to evaluate the presence of subclinical dysphagia in patients with mild multiple sclerosis (MS) using electrophysiological methods. A prospective study of 51 patients with relapsing remitting multiple sclerosis and 18 age-matched healthy adults was investigated. We used electromyography to measure the activity of the submental muscles during swallowing. Electrophysiological recordings of patients were obtained during relapse, after relapse, and at any time in remission period. Clinical dysphagia was found in 12% of MS patients, while electrophysiological swallowing abnormalities were encountered in 33% of patients. Subclinical dysphagia was determined in 35% of patients during an MS relapse, in 20% of patients after a relapse, and in 25% of all 51 patients in the remission period based on EMG findings. Duration of swallowing signal of submental muscles in all MS patients was found to be longer than in normal subjects (p = 0.001). During swallowing of 50 ml of sequential water, the compensatory respiratory cycles occurred more often in MS patients than normal subjects, especially during a relapse (p = 0.005). This is the first study investigating swallowing abnormalities and subclinical dysphagia from the electrophysiological aspect in MS patients with mild disability. The electrophysiological tests described in this study are useful to uncover subclinical dysphagia since they have the advantage of being rapid, easy to apply, non-invasive, and without risk for the patients.

  6. Design, Development and Pre-Flight Testing of the Communications, Navigation, and Networking Reconfigurable Testbed (Connect) to Investigate Software Defined Radio Architecture on the International Space Station

    Science.gov (United States)

    Over, Ann P.; Barrett, Michael J.; Reinhart, Richard C.; Free, James M.; Cikanek, Harry A., III

    2011-01-01

    The Communication Navigation and Networking Reconfigurable Testbed (CoNNeCT) is a NASA-sponsored mission, which will investigate the usage of Software Defined Radios (SDRs) as a multi-function communication system for space missions. A softwaredefined radio system is a communication system in which typical components of the system (e.g., modulators) are incorporated into software. The software-defined capability allows flexibility and experimentation in different modulation, coding and other parameters to understand their effects on performance. This flexibility builds inherent redundancy and flexibility into the system for improved operational efficiency, real-time changes to space missions and enhanced reliability/redundancy. The CoNNeCT Project is a collaboration between industrial radio providers and NASA. The industrial radio providers are providing the SDRs and NASA is designing, building and testing the entire flight system. The flight system will be integrated on the Express Logistics Carrier (ELC) on the International Space Station (ISS) after launch on the H-IIB Transfer Vehicle in 2012. This paper provides an overview of the technology research objectives, payload description, design challenges and pre-flight testing results.

  7. Geologic and hydrologic records of observation wells, test holes, test wells, supply wells, springs, and surface water stations in the Los Alamos area

    International Nuclear Information System (INIS)

    Purtymun, W.D.

    1995-01-01

    Hundreds of holes have been drilled into the Pajarito Plateau and surrounding test areas of the Los Alamos National Laboratory since the end of World War II. They range in depth from a few feet to more than 14,000 ft. The holes were drilled to provide geologic, hydrologic, and engineering information related to development of a water supply, to provide data on the likelihood or presence of subsurface contamination from hazardous and nuclear materials, and for engineering design for construction. The data contained in this report provide a basis for further investigations into the consequences of our past, present, and future interactions with the environment

  8. Nucleus accumbens core medium spiny neuron electrophysiological properties and partner preference behavior in the adult male prairie vole, Microtus ochrogaster.

    Science.gov (United States)

    Willett, Jaime A; Johnson, Ashlyn G; Vogel, Andrea R; Patisaul, Heather B; McGraw, Lisa A; Meitzen, John

    2018-04-01

    Medium spiny neurons (MSNs) in the nucleus accumbens have long been implicated in the neurobiological mechanisms that underlie numerous social and motivated behaviors as studied in rodents such as rats. Recently, the prairie vole has emerged as an important model animal for studying social behaviors, particularly regarding monogamy because of its ability to form pair bonds. However, to our knowledge, no study has assessed intrinsic vole MSN electrophysiological properties or tested how these properties vary with the strength of the pair bond between partnered voles. Here we performed whole cell patch-clamp recordings of MSNs in acute brain slices of the nucleus accumbens core (NAc) of adult male voles exhibiting strong and weak preferences for their respective partnered females. We first document vole MSN electrophysiological properties and provide comparison to rat MSNs. Vole MSNs demonstrated many canonical electrophysiological attributes shared across species but exhibited notable differences in excitability compared with rat MSNs. Second, we assessed male vole partner preference behavior and tested whether MSN electrophysiological properties varied with partner preference strength. Male vole partner preference showed extensive variability. We found that decreases in miniature excitatory postsynaptic current amplitude and the slope of the evoked action potential firing rate to depolarizing current injection weakly associated with increased preference for the partnered female. This suggests that excitatory synaptic strength and neuronal excitability may be decreased in MSNs in males exhibiting stronger preference for a partnered female. Overall, these data provide extensive documentation of MSN electrophysiological characteristics and their relationship to social behavior in the prairie vole. NEW & NOTEWORTHY This research represents the first assessment of prairie vole nucleus accumbens core medium spiny neuron intrinsic electrophysiological properties and

  9. Sedation for paediatric auditory electrophysiology in South Africa

    African Journals Online (AJOL)

    emergency departments and nuclear medicine.1 Added to this is the periodic need ... electrophysiology in the paediatric population in South Africa were not found. ..... to inadequate information technology infrastructure as well as limited data ...

  10. Autoclave Sterilization of PEDOT:PSS Electrophysiology Devices.

    Science.gov (United States)

    Uguz, Ilke; Ganji, Mehran; Hama, Adel; Tanaka, Atsunori; Inal, Sahika; Youssef, Ahmed; Owens, Roisin M; Quilichini, Pascale P; Ghestem, Antoine; Bernard, Christophe; Dayeh, Shadi A; Malliaras, George G

    2016-12-01

    Autoclaving, the most widely available sterilization method, is applied to poly(3,4-ethylenedioxythiophene) doped with polystyrene sulfonate (PEDOT:PSS) electrophysiology devices. The process does not harm morphology or electrical properties, while it effectively kills E. coli intentionally cultured on the devices. This finding paves the way to widespread introduction of PEDOT:PSS electrophysiology devices to the clinic. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Dynamics of intrinsic electrophysiological properties in spinal cord neurones

    DEFF Research Database (Denmark)

    Russo, R E; Hounsgaard, J

    1999-01-01

    The spinal cord is engaged in a wide variety of functions including generation of motor acts, coding of sensory information and autonomic control. The intrinsic electrophysiological properties of spinal neurones represent a fundamental building block of the spinal circuits executing these tasks. ....... Specialised, cell specific electrophysiological phenotypes gradually differentiate during development and are continuously adjusted in the adult animal by metabotropic synaptic interactions and activity-dependent plasticity to meet a broad range of functional demands....

  12. Evaluation of Optogenetic Electrophysiology Tools in Human Stem Cell-Derived Cardiomyocytes

    Directory of Open Access Journals (Sweden)

    Susann Björk

    2017-11-01

    paced beating rates (1, 2 Hz. Cumulating doses of E-4031 produced prolonged APDs, followed by EADs and drug-induced quiescence. These observations were corroborated by patch clamp and contractility measurements. Similar responses, although more modest were seen with the IKs potassium channel blocker JNJ-303. In conclusion, optogenetic measurements of AP waveforms combined with optical pacing compare well with the patch clamp gold standard. Combined with video motion contractile measurements, optogenetic imaging provides an appealing alternative for electrophysiological screening of human cardiomyocyte responses in pharmacological efficacy and safety testings.

  13. [Electrophysiological bases of semantic processing of objects].

    Science.gov (United States)

    Kahlaoui, Karima; Baccino, Thierry; Joanette, Yves; Magnié, Marie-Noële

    2007-02-01

    How pictures and words are stored and processed in the human brain constitute a long-standing question in cognitive psychology. Behavioral studies have yielded a large amount of data addressing this issue. Generally speaking, these data show that there are some interactions between the semantic processing of pictures and words. However, behavioral methods can provide only limited insight into certain findings. Fortunately, Event-Related Potential (ERP) provides on-line cues about the temporal nature of cognitive processes and contributes to the exploration of their neural substrates. ERPs have been used in order to better understand semantic processing of words and pictures. The main objective of this article is to offer an overview of the electrophysiologic bases of semantic processing of words and pictures. Studies presented in this article showed that the processing of words is associated with an N 400 component, whereas pictures elicited both N 300 and N 400 components. Topographical analysis of the N 400 distribution over the scalp is compatible with the idea that both image-mediated concrete words and pictures access an amodal semantic system. However, given the distinctive N 300 patterns, observed only during picture processing, it appears that picture and word processing rely upon distinct neuronal networks, even if they end up activating more or less similar semantic representations.

  14. A brain electrophysiological correlate of depth perception

    International Nuclear Information System (INIS)

    Akay, Ahmet; Celebi, Gurbuz

    2009-01-01

    To investigate brain electrical activity accompanying depth perception using random-dot stereograms. Additional experiments were conducted to ascertain the specificity of this potential to depth perception. In the present study, we performed 3 different and independent experiments on 34 subjects to establish the relationship between depth perception and its cortical electrophysiological correlate. Visual evoked potentials in response to visual stimulation by random-dot stereograms were recorded. To achieve this goal, a data acquisition and analysis system, different from common visual evoked potential recording systems, consisting of 2 personal computers, was used. One of the computers was used to generate the visual stimulus patterns and the other to record and digitally average the potentials evoked by the stimuli. This study was carried out at the Department of Biophysics of Ege University Medical School, Izmir, Turkey, from April to December, 2006. A negative potential component, which is thought to arise in association with depth perception, was recorded from the occipital region from 30 of the 34 subjects. Typically, it had a mean latency of 211.46 ms and 6.40 micron V amplitude. The negative potential is related to depth perception, as this component is present in the responses to stimulus, which carries disparity information but is absent when the stimulus is switched to no disparity information. Additional experiments also showed that the specificity of this component to depth perception becomes evident beyond doubt. (author)

  15. Electrophysiological measurements of spectral sensitivities: a review

    Directory of Open Access Journals (Sweden)

    R.D. DeVoe

    1997-02-01

    Full Text Available Spectral sensitivities of visual systems are specified as the reciprocals of the intensities of light (quantum fluxes needed at each wavelength to elicit the same criterion amplitude of responses. This review primarily considers the methods that have been developed for electrophysiological determinations of criterion amplitudes of slow-wave responses from single retinal cells. Traditional flash methods can require tedious dark adaptations and may yield erroneous spectral sensitivity curves which are not seen in such modifications as ramp methods. Linear response methods involve interferometry, while constant response methods involve manual or automatic adjustments of continuous illumination to keep response amplitudes constant during spectral scans. In DC or AC computerized constant response methods, feedback to determine intensities at each wavelength is derived from the response amplitudes themselves. Although all but traditional flash methods have greater or lesser abilities to provide on-line determinations of spectral sensitivities, computerized constant response methods are the most satisfactory due to flexibility, speed and maintenance of a constant adaptation level

  16. Stimfit: quantifying electrophysiological data with Python

    Directory of Open Access Journals (Sweden)

    Segundo Jose Guzman

    2014-02-01

    Full Text Available Intracellular electrophysiological recordings provide crucial insights into elementary neuronal signals such as action potentials and synaptic currents. Analyzing and interpreting these signals is essential for a quantitative understanding of neuronal information processing, and requires both fast data visualization and ready access to complex analysis routines. To achieve this goal, we have developed Stimfit, a free software package for cellular neurophysiology with a Python scripting interface and a built-in Python shell. The program supports most standard file formats for cellular neurophysiology and other biomedical signals through the Biosig library. To quantify and interpret the activity of single neurons and communication between neurons, the program includes algorithms to characterize the kinetics of presynaptic action potentials and postsynaptic currents, estimate latencies between pre- and postsynaptic events, and detect spontaneously occurring events. We validate and benchmark these algorithms, give estimation errors, and provide sample use cases, showing that Stimfit represents an efficient, accessible and extensible way to accurately analyze and interpret neuronal signals.

  17. [On the first studies of electrophysiology].

    Science.gov (United States)

    de Micheli, Alfredo

    2011-01-01

    A historical outline of the evolution of electrophysiology from the eighteenth century is shortly presented. Topics concerning the so called animal electricity starting from the observations on descharges of Torpedo fish until Bolognese Galvani's researches on the frogs are exposed. The points of view of their oppositionists also are examined. These ones, leaded by the physicist Alessandro Volta, professor in the University of Pavia, believed that electricity detected by galvanists was not inherent to animal but was due to the action of the metallic conductors present in the circuit: contact electricity. Only towards the middle of the nineteenth century the physicist Carlo Matteucci attained to demonstrate the existente of the real animal electricity in form of injury current. It was possible to determine that quantitatively thanks to the capillary electrometer built in 1872 by the French physicist Gabriel Lippmann. This instrument was used by the English physiologist Waller in order to obtain the primitive electrocardiographic tracings in humans (1887). At beginnings of the twentieth century, the Dutch professor Willem Einthoven, of the University of Leiden, introduced his string galvanometer which permitted to allow the modern electrocardiography. So it was possible to record the electrical potentials of myocardial cells, first in vitro, later in isolated and perfused heart, son after in dog's heart in situ and finally in human heart. Therefore now it is possible to effectuate endocardial and epicardial mappings, indispensable in order to diagnose and treat the cardiac arrhythmias.

  18. Electrophysiology of pumpkin seeds: Memristors in vivo.

    Science.gov (United States)

    Volkov, Alexander G; Nyasani, Eunice K; Tuckett, Clayton; Greeman, Esther A; Markin, Vladislav S

    2016-01-01

    Leon Chua, the discoverer of a memristor, theoretically predicted that voltage gated ion channels can be memristors. We recently found memristors in different plants such as the Venus flytrap, Mimosa pudica, Aloe vera, apple fruits, and in potato tubers. There are no publications in literature about the existence of memristors in seeds. The goal of this work was to discover if pumpkin seeds might have memristors. We selected Cucurbita pepo L., cv. Cinderella, Cucurbita maxima L. cv Warty Goblin, and Cucurbita maxima L., cv. Jarrahdale seeds for this analysis. In these seeds, we found the presence of resistors with memory. The analysis was based on cyclic voltammetry where a memristor should manifest itself as a nonlinear two-terminal electrical element, which exhibits a pinched hysteresis loop on a current-voltage plane for any bipolar cyclic voltage input signal. Dry dormant pumpkin seeds have very high electrical resistance without memristive properties. The electrostimulation by bipolar sinusoidal or triangular periodic waves induces electrical responses in imbibed pumpkin seeds with fingerprints of memristors. Tetraethylammonium chloride, an inhibitor of voltage gated K(+) channels, transforms a memristor to a resistor in pumpkin seeds. NPPB (5-Nitro-2-(3-phenylpropylamino)benzoic acid) inhibits the memristive properties of imbibed pumpkin seeds. The discovery of memristors in pumpkin seeds creates a new direction in the understanding of electrophysiological phenomena in seeds.

  19. Introduction to solid supported membrane based electrophysiology.

    Science.gov (United States)

    Bazzone, Andre; Costa, Wagner Steuer; Braner, Markus; Călinescu, Octavian; Hatahet, Lina; Fendler, Klaus

    2013-05-11

    The electrophysiological method we present is based on a solid supported membrane (SSM) composed of an octadecanethiol layer chemisorbed on a gold coated sensor chip and a phosphatidylcholine monolayer on top. This assembly is mounted into a cuvette system containing the reference electrode, a chlorinated silver wire. After adsorption of membrane fragments or proteoliposomes containing the membrane protein of interest, a fast solution exchange is used to induce the transport activity of the membrane protein. In the single solution exchange protocol two solutions, one non-activating and one activating solution, are needed. The flow is controlled by pressurized air and a valve and tubing system within a faraday cage. The kinetics of the electrogenic transport activity is obtained via capacitive coupling between the SSM and the proteoliposomes or membrane fragments. The method, therefore, yields only transient currents. The peak current represents the stationary transport activity. The time dependent transporter currents can be reconstructed by circuit analysis. This method is especially suited for prokaryotic transporters or eukaryotic transporters from intracellular membranes, which cannot be investigated by patch clamp or voltage clamp methods.

  20. Integrated platform and API for electrophysiological data.

    Science.gov (United States)

    Sobolev, Andrey; Stoewer, Adrian; Leonhardt, Aljoscha; Rautenberg, Philipp L; Kellner, Christian J; Garbers, Christian; Wachtler, Thomas

    2014-01-01

    Recent advancements in technology and methodology have led to growing amounts of increasingly complex neuroscience data recorded from various species, modalities, and levels of study. The rapid data growth has made efficient data access and flexible, machine-readable data annotation a crucial requisite for neuroscientists. Clear and consistent annotation and organization of data is not only an important ingredient for reproducibility of results and re-use of data, but also essential for collaborative research and data sharing. In particular, efficient data management and interoperability requires a unified approach that integrates data and metadata and provides a common way of accessing this information. In this paper we describe GNData, a data management platform for neurophysiological data. GNData provides a storage system based on a data representation that is suitable to organize data and metadata from any electrophysiological experiment, with a functionality exposed via a common application programming interface (API). Data representation and API structure are compatible with existing approaches for data and metadata representation in neurophysiology. The API implementation is based on the Representational State Transfer (REST) pattern, which enables data access integration in software applications and facilitates the development of tools that communicate with the service. Client libraries that interact with the API provide direct data access from computing environments like Matlab or Python, enabling integration of data management into the scientist's experimental or analysis routines.

  1. Closed-loop, open-source electrophysiology

    Directory of Open Access Journals (Sweden)

    John D Rolston

    2010-09-01

    Full Text Available Multiple extracellular microelectrodes (multi-electrode arrays, or MEAs effectively record rapidly varying neural signals, and can also be used for electrical stimulation. Multi-electrode recording can serve as artificial output (efferents from a neural system, while complex spatially and temporally targeted stimulation can serve as artificial input (afferents to the neuronal network. Multi-unit or local field potential recordings can not only be used to control real world artifacts, such as prostheses, computers or robots, but can also trigger or alter subsequent stimulation. Real-time feedback stimulation may serve to modulate or normalize aberrant neural activity, to induce plasticity, or to serve as artificial sensory input. Despite promising closed-loop applications, commercial electrophysiology systems do not yet take advantage of the bidirectional capabilities of multi-electrodes, especially for use in freely moving animals. We addressed this lack of tools for closing the loop with NeuroRighter, an open-source system including recording hardware, stimulation hardware, and control software with a graphical user interface. The integrated system is capable of multi-electrode recording and simultaneous patterned microstimulation triggered by recordings with minimal stimulation artifact. The potential applications of closed-loop systems as research tools and clinical treatments are broad; we provide one example where epileptic activity recorded by a multi-electrode probe is used to trigger targeted stimulation, via that probe, to freely moving rodents.

  2. Electrophysiological mapping of novel prefrontal - cerebellar pathways

    Directory of Open Access Journals (Sweden)

    Thomas C Watson

    2009-08-01

    Full Text Available Whilst the cerebellum is predominantly considered a sensorimotor control structure, accumulating evidence suggests that it may also subserve non motor functions during cognition. However, this possibility is not universally accepted, not least because the nature and pattern of links between higher cortical structures and the cerebellum are poorly characterized. We have therefore used in vivo electrophysiological methods in anaesthetized rats to directly investigate connectivity between the medial prefrontal cortex (prelimbic subdivision, PrL and the cerebellum. Stimulation of deep layers of PrL evoked distinct field potentials in the cerebellar cortex with a mean latency to peak of approximately 35ms. These responses showed a well-defined topography, and were maximal in lobule VII of the contralateral vermis (a known oculomotor centre; they were not attenuated by local anesthesia of the overlying M2 motor cortex, though M2 stimulation did evoke field potentials in lobule VII with a shorter latency. Single-unit recordings showed that prelimbic cortical stimulation elicits complex spikes in lobule VII Purkinje cells, indicating transmission via a previously undescribed cerebro-olivocerebellar pathway. Our results therefore establish a physiological basis for communication between PrL and the cerebellum. The role(s of this pathway remain to be resolved, but presumably relate to control of eye movements and/or distributed networks associated with integrated prefrontal cortical functions.

  3. Additional safety assessments, follow-up of stress tests of the French nuclear power stations. Action plan of the nuclear safety authority

    International Nuclear Information System (INIS)

    2012-01-01

    This document presents the French national action plan defined by the Nuclear Safety Authority (ASN) in compliance with the recommendations made by the ENSREG (European nuclear safety regulators group). It refers to decisions taken at the national level after the Fukushima accident, recommendations after European stress tests, and recommendations after the extraordinary meeting of contracting parties at the Convention on Nuclear Safety of August 2012. For different topics, this document recalls the recommendations made by the peer review, indicates the ASN's opinion and progress or ASN's requirements for different power stations. The first part addresses the recommendations made by peers and based on the European review. Topics concern natural hazards (effects, detection, inspections and controls related to earthquakes, margin assessment with respect to flooding and natural hazards), the loss of safety systems (cooling systems, electricity supplies, actions, instruments, training, and so on), the management of a severe accident (reference levels, measures, guides, exercises, training, management of contaminated water, radiation protection, premises). The second part deals with topics addressed within the frame of the Convention: national organisations, organisations in an emergency and post-accidental situation, international cooperation. A third part addresses the follow-up of additional measures issued by the ASN

  4. Electrophysiological assessment of water stress in fruit-bearing woody plants.

    Science.gov (United States)

    Ríos-Rojas, Liliana; Tapia, Franco; Gurovich, Luis A

    2014-06-15

    Development and evaluation of a real-time plant water stress sensor, based on the electrophysiological behavior of fruit-bearing woody plants is presented. Continuous electric potentials are measured in tree trunks for different irrigation schedules, inducing variable water stress conditions; results are discussed in relation to soil water content and micro-atmospheric evaporative demand, determined continuously by conventional sensors, correlating this information with tree electric potential measurements. Systematic and differentiable patterns of electric potentials for water-stressed and no-stressed trees in 2 fruit species are presented. Early detection and recovery dynamics of water stress conditions can also be monitored with these electrophysiology sensors, which enable continuous and non-destructive measurements for efficient irrigation scheduling throughout the year. The experiment is developed under controlled conditions, in Faraday cages located at a greenhouse area, both in Persea americana and Prunus domestica plants. Soil moisture evolution is controlled using capacitance sensors and solar radiation, temperature, relative humidity, wind intensity and direction are continuously registered with accurate weather sensors, in a micro-agrometeorological automatic station located at the experimental site. The electrophysiological sensor has two stainless steel electrodes (measuring/reference), inserted on the stem; a high precision Keithley 2701 digital multimeter is used to measure plant electrical signals; an algorithm written in MatLab(®), allows correlating the signal to environmental variables. An electric cyclic behavior is observed (circadian cycle) in the experimental plants. For non-irrigated plants, the electrical signal shows a time positive slope and then, a negative slope after restarting irrigation throughout a rather extended recovery process, before reaching a stable electrical signal with zero slope. Well-watered plants presented a

  5. Corrective Action Investigation Plan for Corrective Action Unit 490: Station 44 Burn Area, Tonopah Test Range, Nevada (with Record of Technical Change No.1)

    International Nuclear Information System (INIS)

    2000-01-01

    This Corrective Action Investigation Plan (CAIP) contains the U.S. Department of Energy, Nevada Operations Office's approach to collect the data necessary to evaluate corrective action alternatives appropriate for the closure of Corrective Action Unit (CAU) 490 under the Federal Facility Agreement and Consent Order. Corrective Active Unit 490 consists of four Corrective Action Sites (CASs): 03-56-001-03BA, Fire Training Area (FTA); RG-56-001-RGBA, Station 44 Burn Area; 03-58-001-03FN, Sandia Service Yard; and 09-54-001-09L2, Gun Propellant Burn Area. These CASs are located at the Tonopah Test Range near Areas 3 and 9. Historically, the FTA was used for training exercises where tires and wood were ignited with diesel fuel. Records indicate that water and carbon dioxide were the only extinguishing agents used during these training exercises. The Station 44 Burn Area was used for fire training exercises and consisted of two wooden structures. The two burn areas (ignition of tires, wood, and wooden structures with diesel fuel and water) were limited to the building footprints (10 ft by 10 ft each). The Sandia Service Yard was used for storage (i.e., wood, tires, metal, electronic and office equipment, construction debris, and drums of oil/grease) from approximately 1979 to 1993. The Gun Propellant Burn Area was used from the 1960s to 1980s to burn excess artillery gun propellant, solid-fuel rocket motors, black powder, and deteriorated explosives; additionally, the area was used for the disposal of experimental explosive items. Based on site history, the focus of the field investigation activities will be to: (1) determine the presence of contaminants of potential concern (COPCs) at each CAS, (2) determine if any COPCs exceed field-screening levels and/or preliminary action levels, and (3) determine the nature and extent of contamination with enough certainty to support selection of corrective action alternatives for each CAS. The scope of this CAIP is to resolve the

  6. Corrective Action Investigation Plan for Corrective Action Unit 490: Station 44 Burn Area, Tonopah Test Range, Nevada (with Record of Technical Change No.1)

    Energy Technology Data Exchange (ETDEWEB)

    U.S. Department of Energy, Nevada Operations Office

    2000-06-09

    This Corrective Action Investigation Plan (CAIP) contains the U.S. Department of Energy, Nevada Operations Office's approach to collect the data necessary to evaluate corrective action alternatives appropriate for the closure of Corrective Action Unit (CAU) 490 under the Federal Facility Agreement and Consent Order. Corrective Active Unit 490 consists of four Corrective Action Sites (CASs): 03-56-001-03BA, Fire Training Area (FTA); RG-56-001-RGBA, Station 44 Burn Area; 03-58-001-03FN, Sandia Service Yard; and 09-54-001-09L2, Gun Propellant Burn Area. These CASs are located at the Tonopah Test Range near Areas 3 and 9. Historically, the FTA was used for training exercises where tires and wood were ignited with diesel fuel. Records indicate that water and carbon dioxide were the only extinguishing agents used during these training exercises. The Station 44 Burn Area was used for fire training exercises and consisted of two wooden structures. The two burn areas (ignition of tires, wood, and wooden structures with diesel fuel and water) were limited to the building footprints (10 ft by 10 ft each). The Sandia Service Yard was used for storage (i.e., wood, tires, metal, electronic and office equipment, construction debris, and drums of oil/grease) from approximately 1979 to 1993. The Gun Propellant Burn Area was used from the 1960s to 1980s to burn excess artillery gun propellant, solid-fuel rocket motors, black powder, and deteriorated explosives; additionally, the area was used for the disposal of experimental explosive items. Based on site history, the focus of the field investigation activities will be to: (1) determine the presence of contaminants of potential concern (COPCs) at each CAS, (2) determine if any COPCs exceed field-screening levels and/or preliminary action levels, and (3) determine the nature and extent of contamination with enough certainty to support selection of corrective action alternatives for each CAS. The scope of this CAIP is to resolve

  7. The role of neuro-electrophysiological diagnostic tests in clinical ...

    African Journals Online (AJOL)

    East African Medical Journal. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 83, No 1 (2006) >. Log in or Register to get access to full text downloads.

  8. Electrophysiology of Cranial Nerve Testing: Cranial Nerves IX and X.

    Science.gov (United States)

    Martinez, Alberto R M; Martins, Melina P; Moreira, Ana Lucila; Martins, Carlos R; Kimaid, Paulo A T; França, Marcondes C

    2018-01-01

    The cranial nerves IX and X emerge from medulla oblongata and have motor, sensory, and parasympathetic functions. Some of these are amenable to neurophysiological assessment. It is often hard to separate the individual contribution of each nerve; in fact, some of the techniques are indeed a composite functional measure of both nerves. The main methods are the evaluation of the swallowing function (combined IX and X), laryngeal electromyogram (predominant motor vagal function), and heart rate variability (predominant parasympathetic vagal function). This review describes, therefore, the techniques that best evaluate the major symptoms presented in IX and X cranial nerve disturbance: dysphagia, dysphonia, and autonomic parasympathetic dysfunction.

  9. Electrophysiology of Cranial Nerve Testing: Spinal Accessory and Hypoglossal Nerves.

    Science.gov (United States)

    Stino, Amro M; Smith, Benn E

    2018-01-01

    Multiple techniques have been developed for the electrodiagnostic evaluation of cranial nerves XI and XII. Each of these carries both benefits and limitations, with more techniques and data being available in the literature for spinal accessory than hypoglossal nerve evaluation. Spinal accessory and hypoglossal neuropathy are relatively uncommon cranial mononeuropathies that may be evaluated in the outpatient electrodiagnostic laboratory setting. A review of available literature using PubMed was conducted regarding electrodiagnostic technique in the evaluation of spinal accessory and hypoglossal nerves searching for both routine nerve conduction studies and repetitive nerve conduction studies. The review provided herein provides a resource by which clinical neurophysiologists may develop and implement clinical and research protocols for the evaluation of both of these lower cranial nerves in the outpatient setting.

  10. Motor Neuropathy in Hypothyroidism: Clinical and Electrophysiological Findings

    Directory of Open Access Journals (Sweden)

    Sabina Yeasmin

    2009-11-01

    Full Text Available Background: Hypothyroidism is a clinical condition associated with low levels of thyroid hormones with raised TSH. Peripheral neuropathy may be associated with hypothyroidism which usually develops insidiously over a long period of time due to irregular taking of drugs or lack of thyroid hormone replacement. Objectives: The present study was done to evaluate the clinical and electro-physiological findings in hypothyroid patients in order to evaluate the neuromuscular dysfunction as well as motor neuropathy. Method: In this study, 70 subjects with the age range from 20 to 50 years of both sexes were included of whom 40 hypothyroids were taken in study group (B with the duration of 6 months to 5 years and 30 healthy euthyroid subjects were taken as control (Group A. On the basis of their TSH level, group B was further divided into group B1 with TSH level <60 MIU /L (less severe and group B2 with TSH >60 MIU /L (severe group. The d latency and NCV for motor nerve function were measured by NCV machine in median and ulnar nerve for upper limb and in common peroneal nerve for lower limb. TT3, TT4 were measured by RIA and TSH by IRMA method. All these parameters were measured on the day 1 (one of their first visit. Data were analysed statistically by ANOVA and Z test. Result: Both TT3, TT4 levels were significantly (P<0.01 lower in hypothyroids in comparison to those of control. Diminished or absence of most of the deep tendon reflexes were found in all the hypothyroids. Most of the patients (67.5% showed significantly higher (P <0.01 motor distal latencies (MDL with lower (P> 0.001 conduction velocities (MNCV and all these changes were more marked in group B2. Conclusion: So, the study revealed that motor neuropathy may be a consequence of hypothyroidism.DOI: 10.3329/bsmmuj.v1i1.3692 Key Words: Hypothyroidism; neuropathy; electrophysiology BSMMU J 2008; 1(1: 15-18

  11. Myokit: A simple interface to cardiac cellular electrophysiology.

    Science.gov (United States)

    Clerx, Michael; Collins, Pieter; de Lange, Enno; Volders, Paul G A

    2016-01-01

    Myokit is a new powerful and versatile software tool for modeling and simulation of cardiac cellular electrophysiology. Myokit consists of an easy-to-read modeling language, a graphical user interface, single and multi-cell simulation engines and a library of advanced analysis tools accessible through a Python interface. Models can be loaded from Myokit's native file format or imported from CellML. Model export is provided to C, MATLAB, CellML, CUDA and OpenCL. Patch-clamp data can be imported and used to estimate model parameters. In this paper, we review existing tools to simulate the cardiac cellular action potential to find that current tools do not cater specifically to model development and that there is a gap between easy-to-use but limited software and powerful tools that require strong programming skills from their users. We then describe Myokit's capabilities, focusing on its model description language, simulation engines and import/export facilities in detail. Using three examples, we show how Myokit can be used for clinically relevant investigations, multi-model testing and parameter estimation in Markov models, all with minimal programming effort from the user. This way, Myokit bridges a gap between performance, versatility and user-friendliness. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Electrophysiological evaluation of Wolff-Parkinson-White Syndrome

    Science.gov (United States)

    Brembilla-Perrot, Beatrice

    2002-01-01

    Sudden death might complicate the follow-up of symptomatic patients with the Wolff-Parkinson-White syndrome (WPW) and might be the first event in patients with asymptomatic WPW. The risk of sudden death is increased in some clinical situations. Generally, the noninvasive studies are unable to predict the risk of sudden death correctly . The electrophysiological study is the best means to detect the risk of sudden death and to evaluate the nature of symptoms. Methods used to define the prognosis of WPW are well-defined. At first the maximal rate of conduction through the accessory pathway is evaluated; programmed atrial stimulation using 1 and 2 extrastimuli delivered at different cycle lengths is then used to determine the accessory pathway refractory period and to induce a supraventricular tachycardia. These methods should be performed in the control state and repeated in adrenergic situations either during exercise test or more simply during a perfusion of small doses of isoproterenol. The induction of an atrial fibrillation with rapid conduction through the accessory pathway (> 240/min in control state, > 300/min after isoproterenol) is the sign of a form of WPW at risk of sudden death. PMID:16951730

  13. Electrophysiological evaluation of Wolff-Parkinson-White Syndrome

    Directory of Open Access Journals (Sweden)

    Béatrice Brembilla-Perrot

    2002-10-01

    Full Text Available Sudden death might complicate the follow-up of symptomatic patients with the Wolff-Parkinson-White syndrome (WPW and might be the first event in patients with asymptomatic WPW. The risk of sudden death is increased in some clinical situations. Generally, the noninvasive studies are unable to predict the risk of sudden death correctly . The electrophysiological study is the best means to detect the risk of sudden death and to evaluate the nature of symptoms. Methods used to define the prognosis of WPW are well-defined. At first the maximal rate of conduction through the accessory pathway is evaluated; programmed atrial stimulation using 1 and 2 extrastimuli delivered at different cycle lengths is then used to determine the accessory pathway refractory period and to induce a supraventricular tachycardia. These methods should be performed in the control state and repeated in adrenergic situations either during exercise test or more simply during a perfusion of small doses of isoproterenol. The induction of an atrial fibrillation with rapid conduction through the accessory pathway (> 240/min in control state, > 300/min after isoproterenol is the sign of a form of WPW at risk of sudden death.

  14. Encoding and Decoding Models in Cognitive Electrophysiology

    Directory of Open Access Journals (Sweden)

    Christopher R. Holdgraf

    2017-09-01

    Full Text Available Cognitive neuroscience has seen rapid growth in the size and complexity of data recorded from the human brain as well as in the computational tools available to analyze this data. This data explosion has resulted in an increased use of multivariate, model-based methods for asking neuroscience questions, allowing scientists to investigate multiple hypotheses with a single dataset, to use complex, time-varying stimuli, and to study the human brain under more naturalistic conditions. These tools come in the form of “Encoding” models, in which stimulus features are used to model brain activity, and “Decoding” models, in which neural features are used to generated a stimulus output. Here we review the current state of encoding and decoding models in cognitive electrophysiology and provide a practical guide toward conducting experiments and analyses in this emerging field. Our examples focus on using linear models in the study of human language and audition. We show how to calculate auditory receptive fields from natural sounds as well as how to decode neural recordings to predict speech. The paper aims to be a useful tutorial to these approaches, and a practical introduction to using machine learning and applied statistics to build models of neural activity. The data analytic approaches we discuss may also be applied to other sensory modalities, motor systems, and cognitive systems, and we cover some examples in these areas. In addition, a collection of Jupyter notebooks is publicly available as a complement to the material covered in this paper, providing code examples and tutorials for predictive modeling in python. The aim is to provide a practical understanding of predictive modeling of human brain data and to propose best-practices in conducting these analyses.

  15. Development and Certification of Station Development Test Objective (SDTO) Experiment # 15012-U, "Near RealTime Water Quality Monitoring Demonstration for ISS Biocides Using Colorimetric Solid Phase Extraction (CSPE)"

    Science.gov (United States)

    Gazda, Daniel B.; Nolan, Daniel J.; Rutz, Jeffrey A.; Shcultz, John R.; Siperko, Lorraine M.; Porter, Marc D,; Lipert, Robert J.; Limardo, Jose G.; McCoy, J. Torin

    2009-01-01

    Scientists and engineers from the Wyle Integrated Science and Engineering Group are working with researchers at the University of Utah and Iowa State University to develop and certify an experimental water quality monitoring kit based on Colorimetric Solid Phase Extraction (CSPE). The kit will be launched as a Station Development Test Objective (SDTO) experiment and evaluated on the International Space Station (ISS) to determine the acceptability of CSPE technology for routine inflight water quality monitoring. Iodine and silver, the biocides used in the US and Russian on-orbit water systems, will serve as test analytes for the technology evaluation. This manuscript provides an overview of the CSPE SDTO experiment and details the development and certification of the experimental water quality monitoring kit. Initial results from reagent and standard solution stability testing and environmental testing performed on the kit hardware are also reported.

  16. Microbiological Tests Performed During the Design of the International Space Station Environmental Control and Life Support Systems. Part 1, Bulk Phase. Part 1; Bulk Phase

    Science.gov (United States)

    Roman, Monsi C.; Mittelman, Marc W.

    2010-01-01

    The design and manufacturing of the main Environmental Control and Life Support Systems (ECLSS) for the United States segments of the International Space Station (ISS) was an involved process that started in the mid 1980s, with the assessment and testing of competing technologies that could be used to clean the air and recycle water. It culminated in 2009 with the delivery and successful activation of the Water Recovery System (WRS) water processor (WP). The ECLSS required the work of a team of engineers and scientist working together to develop systems that could clean and/or recycle human metabolic loads to maintain a clean atmosphere and provide the crew clean water. One of the main goals of the ECLSS is to minimize the time spent by the crew worrying about vital resources not available in the vacuum of space, which allows them to spend most of their time learning to live in a microgravity environment many miles from the comforts of Earth and working on science experiments. Microorganisms are a significant part of the human body as well as part of the environment that we live in. Therefore, the ISS ECLSS design had to take into account the effect microorganisms have on the quality of stored water and wastewater, as well as that of the air systems. Hardware performance issues impacted by the accumulation of biofilm and/or microbiologically influenced corrosion were also studied during the ECLSS development stages. Many of the tests that were performed had to take into account the unique aspects of a microgravity environment as well as the challenge of understanding how to design systems that could not be sterilized or maintained in a sterile state. This paper will summarize the work of several studies that were performed to assess the impacts and/or to minimize the effects of microorganisms in open, semi-closed and closed loop life support system. The biofilm and biodeterioration studies that were performed during the design and test periods will be presented in

  17. Electrophysiological Evidence in Schizophrenia in Relation to Treatment Response

    Directory of Open Access Journals (Sweden)

    Kazuki Sueyoshi

    2018-06-01

    Full Text Available Several domains of cognitive function, e.g., verbal memory, information processing, fluency, attention, and executive function are impaired in patients with schizophrenia. Cognitive impairments in schizophrenia have attracted interests as a treatment target, because they are considered to greatly affect functional outcome. Electrophysiological markers, including electroencephalogram (EEG, particularly, event-related potentials, have contributed to psychiatric research and clinical practice. In this review, we provide a summary of studies relating electrophysiological findings to cognitive performance in schizophrenia. Electrophysiological indices may provide an objective marker of cognitive processes, contributing to the development of effective interventions to improve cognitive and social outcomes. Further efforts to understand biological mechanisms of cognitive disturbances, and develop effective therapeutics are warranted.

  18. Electrophysiological Source Imaging: A Noninvasive Window to Brain Dynamics.

    Science.gov (United States)

    He, Bin; Sohrabpour, Abbas; Brown, Emery; Liu, Zhongming

    2018-06-04

    Brain activity and connectivity are distributed in the three-dimensional space and evolve in time. It is important to image brain dynamics with high spatial and temporal resolution. Electroencephalography (EEG) and magnetoencephalography (MEG) are noninvasive measurements associated with complex neural activations and interactions that encode brain functions. Electrophysiological source imaging estimates the underlying brain electrical sources from EEG and MEG measurements. It offers increasingly improved spatial resolution and intrinsically high temporal resolution for imaging large-scale brain activity and connectivity on a wide range of timescales. Integration of electrophysiological source imaging and functional magnetic resonance imaging could further enhance spatiotemporal resolution and specificity to an extent that is not attainable with either technique alone. We review methodological developments in electrophysiological source imaging over the past three decades and envision its future advancement into a powerful functional neuroimaging technology for basic and clinical neuroscience applications.

  19. To4, the first Tityus obscurus β-toxin fully electrophysiologically characterized on human sodium channel isoforms.

    Science.gov (United States)

    Duque, Harry Morales; Mourão, Caroline Barbosa Farias; Tibery, Diogo Vieira; Barbosa, Eder Alves; Campos, Leandro Ambrósio; Schwartz, Elisabeth Ferroni

    2017-09-01

    Many scorpion toxins that act on sodium channels (NaScTxs) have been characterized till date. These toxins may act modulating the inactivation or the activation of sodium channels and are named α- or β-types, respectively. Some venom toxins from Tityus obscurus (Buthidae), a scorpion widely distributed in the Brazilian Amazon, have been partially characterized in previous studies; however, little information about their electrophysiological role on sodium ion channels has been published. In the present study, we describe the purification, identification and electrophysiological characterization of a NaScTx, which was first described as Tc54 and further fully sequenced and renamed To4. This toxin shows a marked β-type effect on different sodium channel subtypes (hNa v 1.1-hNa v 1.7) at low concentrations, and has more pronounced activity on hNa v 1.1, hNa v 1.2 and hNa v 1.4. By comparing To4 primary structure with other Tityus β-toxins which have already been electrophysiologically tested, it is possible to establish some key amino acid residues for the sodium channel activity. Thus, To4 is the first toxin from T. obscurus fully electrophysiologically characterized on different human sodium channel isoforms. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. The Acoustic Lens Design and in Vivo Use of a Multifunctional Catheter Combining Intracardiac Ultrasound Imaging and Electrophysiology Sensing

    Science.gov (United States)

    Stephens, Douglas N.; Cannata, Jonathan; Liu, Ruibin; Zhao, Jian Zhong; Shung, K. Kirk; Nguyen, Hien; Chia, Raymond; Dentinger, Aaron; Wildes, Douglas; Thomenius, Kai E.; Mahajan, Aman; Shivkumar, Kalyanam; Kim, Kang; O’Donnell, Matthew; Sahn, David

    2009-01-01

    A multifunctional 9F intracardiac imaging and electrophysiology mapping catheter was developed and tested to help guide diagnostic and therapeutic intracardiac electrophysiology (EP) procedures. The catheter tip includes a 7.25-MHz, 64-element, side-looking phased array for high resolution sector scanning. Multiple electrophysiology mapping sensors were mounted as ring electrodes near the array for electrocardiographic synchronization of ultrasound images. The catheter array elevation beam performance in particular was investigated. An acoustic lens for the distal tip array designed with a round cross section can produce an acceptable elevation beam shape; however, the velocity of sound in the lens material should be approximately 155 m/s slower than in tissue for the best beam shape and wide bandwidth performance. To help establish the catheter’s unique ability for integration with electrophysiology interventional procedures, it was used in vivo in a porcine animal model, and demonstrated both useful intracardiac echocardiographic visualization and simultaneous 3-D positional information using integrated electroanatomical mapping techniques. The catheter also performed well in high frame rate imaging, color flow imaging, and strain rate imaging of atrial and ventricular structures. PMID:18407850

  1. Structural Verification of the First Orbital Wonder of the World - The Structural Testing and Analysis of the International Space Station (ISS)

    Science.gov (United States)

    Zipay, John J.; Bernstein, Karen S.; Bruno, Erica E.; Deloo, Phillipe; Patin, Raymond

    2012-01-01

    The International Space Station (ISS) can be considered one of the structural engineering wonders of the world. On par with the World Trade Center, the Colossus of Rhodes, the Statue of Liberty, the Great Pyramids, the Petronas towers and the Burj Khalifa skyscraper of Dubai, the ambition and scope of the ISS structural design, verification and assembly effort is a truly global success story. With its on-orbit life projected to be from its beginning in 1998 to the year 2020 (and perhaps beyond), all of those who participated in its development can consider themselves part of an historic engineering achievement representing all of humanity. The structural design and verification of the ISS could be the subject of many scholarly papers. Several papers have been written on the structural dynamic characterization of the ISS once it was assembled on-orbit [1], but the ground-based activities required to assure structural integrity and structural life of the individual elements from delivery to orbit through assembly and planned on-orbit operations have never been totally summarized. This paper is intended to give the reader an overview of some of the key decisions made during the structural verification planning for the elements of the U.S. On-Orbit Segment (USOS) as well as to summarize the many structural tests and structural analyses that were performed on its major elements. An effort is made for this paper to be summarily comprehensive, but as with all knowledge capture efforts of this kind, there are bound to be errors of omission. Should the reader discover any of these, please feel free to contact the principal author. The ISS (Figure 1) is composed of pre-integrated truss segments and pressurized elements supplied by NASA, the Russian Federal Space Agency (RSA), the European Space Agency (ESA) and the Japanese Aerospace Exploration Agency (JAXA). Each of these elements was delivered to orbit by a launch vehicle and connected to one another either robotically or

  2. Automatic system of tests for control equipment in combined cycle power stations; Sistema automatico de pruebas para equipos de control en centrales de ciclo combinado

    Energy Technology Data Exchange (ETDEWEB)

    Martinez M, Miguel A; Flores L, Zenon; Delgadillo V, Miguel A; Gutierrez A, Ruben [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2001-07-01

    This article deals on the Automatic System of Tests, denominated PROBADOR, used by the Gerencia de Control e Instrumentation (GCI) of the Instituto de Investigaciones Electricas (IIE)for the accomplishment of dynamic tests in laboratory, to the systems of acquisition and control developed with the electronic line SAC-IIE that are installed in the Thermoelectric Power station of Combined Cycle (CTCC) of Dos Bocas, Veracruz and Gomez Palacio, Durango, Mexico. Also the architecture, the functions that are carried out in the equipment of the System of Acquisition and control (SAC) and in the personal computer (PC) that conforms it are described, as well as the methodology used for the development of the tests. The PC constitutes Interface Man-Machine (IMM) and in the SAC equipment the simulation of the processes is made (by means of the execution of algebraic-differential equations) in the compressor, combustion chamber, gas turbine, heat recuperators, steam turbines and condenser equipment that integrate a CTCC. The equations that are used are based in the thermodynamics, flow dynamics and heat transfer; they become attached to the real process with a margin of error that is estimated in 10%. Finally, the tendencies of the PROBADOR and the technical and economic advantages are described that it has provided for the improvement in the performance of the control systems, before different situations, with no need to have the real process. [Spanish] Este articulo versa sobre el Sistema Automatico de Pruebas, denominado PROBADOR, utilizado por la Gerencia de Control e Instrumentacion (GCI) del Instituto de Investigaciones Electricas para la realizacion de pruebas dinamicas en laboratorio, a los sistemas de adquisicion y control desarrollado con la linea electronica SAC-IIE que estan instalados en las Centrales Termoelectricas de Ciclo Combinado (CTCC) de Dos Bocas, Veracruz y Gomez Palacio, Durango, Mexico. Tambien se describen la arquitectura, las funciones que se llevan

  3. OptoDyCE: Automated system for high-throughput all-optical dynamic cardiac electrophysiology

    Science.gov (United States)

    Klimas, Aleksandra; Yu, Jinzhu; Ambrosi, Christina M.; Williams, John C.; Bien, Harold; Entcheva, Emilia

    2016-02-01

    In the last two decades, market were due to cardiac toxicity, where unintended interactions with ion channels disrupt the heart's normal electrical function. Consequently, all new drugs must undergo preclinical testing for cardiac liability, adding to an already expensive and lengthy process. Recognition that proarrhythmic effects often result from drug action on multiple ion channels demonstrates a need for integrative and comprehensive measurements. Additionally, patient-specific therapies relying on emerging technologies employing stem-cell derived cardiomyocytes (e.g. induced pluripotent stem-cell-derived cardiomyocytes, iPSC-CMs) require better screening methods to become practical. However, a high-throughput, cost-effective approach for cellular cardiac electrophysiology has not been feasible. Optical techniques for manipulation and recording provide a contactless means of dynamic, high-throughput testing of cells and tissues. Here, we consider the requirements for all-optical electrophysiology for drug testing, and we implement and validate OptoDyCE, a fully automated system for all-optical cardiac electrophysiology. We demonstrate the high-throughput capabilities using multicellular samples in 96-well format by combining optogenetic actuation with simultaneous fast high-resolution optical sensing of voltage or intracellular calcium. The system can also be implemented using iPSC-CMs and other cell-types by delivery of optogenetic drivers, or through the modular use of dedicated light-sensitive somatic cells in conjunction with non-modified cells. OptoDyCE provides a truly modular and dynamic screening system, capable of fully-automated acquisition of high-content information integral for improved discovery and development of new drugs and biologics, as well as providing a means of better understanding of electrical disturbances in the heart.

  4. Guidelines for Learning Stations.

    Science.gov (United States)

    Fehrle, Carl C.; Schulz, Jolene

    Guidelines for designing and planning learning stations for pupils at the elementary grade level include suggestions on how to develop a station that will be successful in meeting the learners' needs. Instructions for the use of tapes at a station and matching pupils with stations are given, as are guidelines on classroom arrangement and record…

  5. Clinical and Electrophysiological Report of a Unilateral Retinitis Pigmentosa Case

    Directory of Open Access Journals (Sweden)

    Sedaghat MR

    2014-04-01

    Full Text Available Introduction: To describe clinical and electrophysiological features of a patient with unilateral Retinitis Pigmentosa (RP. Case: A 29-year-old female with a long history of progressive visual disturbance in the right eye has undergone multiple eye examinations during the past eight years. There was nothing noticeable in her past medical and ocular history. Comprehensive eye examinations were done in the first visit. All data was suggestive of right eye RP. Posterior segment fundal examination findings were: a pallor waxy disc, vessel attenuation, and extended pigmentary degeneration of the mid-peripheral retina. The left eye examination was normal. Comparing the automated 60 degree and 30 degree visual fields of both eyes obviously showed significant defects in the right eye visual field but normal in the left eye.  All of the probable infectious agents, which can cause similar ocular manifestations, were ruled out by serological tests. The standard photopic and scotopic electroretinographies were significantly reduced in amplitude in the right eye; however, they were normal in the left eye. Also, the standard Electro-Oculography (EOG results were the same as the Electro-Retinography (ERG ones in both eyes. Eye examinations were normal in other family members. Over an eight-year follow-up period, progressive deteriorating vision has gradually become more noticeable in the right eye. The left eye has been completely normal since.  This data was compatible with the Francois and Verriesr unilateral RP diagnostic criteria. Conclusion: Clinical signs and symptoms, a minimum of a five-year follow-up period, and confirmatory ERG and EOG are very helpful to diagnose andaffirm the case of unilateral RP.

  6. Development of method for detecting signs deterioration in insulator of high-voltage motors. 2. Test Results of a new on-line partial discharge monitor for high-voltage motors in nuclear power stations

    International Nuclear Information System (INIS)

    Tochio, Atsushi; Kaneda, Yoshiharu; Urakawa, Nobuo

    2000-01-01

    For the purpose of early detection of deterioration of insulators in high-voltage motors which are widely utilized in nuclear power stations, a new on-line partial discharge (PD) monitor was developed and was tested for sixteen motors which were practically running in nuclear power stations. From the test results, it is seen that (1) good signal to noise ratio is obtained by adopting a two frequency correlation method, (2) a resistance temperature detector (RTD) in a motor has sufficient sensitivity to detect PD, (3) when RTD is not installed or is unable to use for this purpose, a radio frequency current transformer (RFCT) can be utilized, although its sensitivity is about 1/10 of that of the RTD monitor. Finally we found a good correlation between the results of this on-line method and the conventional off-line method in which the insulator resistance of a concerned motor was measured during its shut-down, and thereby we demonstrated that this method could be applicable to the on-line test of high-voltage motors in nuclear power stations. (author)

  7. Electrophysiologic studies of neronal activities under ischemia condition.

    Science.gov (United States)

    Huang, Shun-Ho; Wang, Ping-Hsien; Chen, Jia-Jin Jason

    2008-01-01

    Substrate with integrated microelectrode arrays (MEAs) provides an alternative electrophysiological method. With MEAS, one can measure the impedance and elicit electrical stimulation from multiple sites of MEAs to determine the electrophysiological conditions of cells. The aims of this research were to construct an impedance and action potential measurement system for neurons cultured on MEAs for observing the electrophysiological signal transmission in neuronal network during glucose and oxygen deprivation (OGD). An extracellular stimulator producing the biphasic micro-current pulse for neuron stimulation was built in this study. From the time-course recording of impedance, OGD condition effectively induced damage in neurons in vitro. It is known that the results of cell stimulation are affected by electrode impedance, so does the result of neuron cells covered on the electrode can measure the sealing resistance. For extracellular stimulation study, cortical neuronal activity was recorded and the suitable stimulation window was determined. However, the stimulation results were affected by electrode impedance as well as sealing impedance resulting from neuron cells covering the electrode. Further development of surface modification for cultured neuron network should provide a better way for in vitro impedance and electrophysiological measurements.

  8. Reversible electrophysiological abnormalities in acute secondary hyperkalemic paralysis

    OpenAIRE

    Karkal R Naik; Aralikatte O Saroja; Mallikarjun S Khanpet

    2012-01-01

    Hyperkalemia manifests clinically with acute neuromuscular paralysis, which can simulate Guillain Barr? syndrome (GBS) and other causes of acute flaccid paralysis. Primary hyperkalemic paralysis occurs from genetic defects in the sodium channel, and secondary hyperkalemic paralysis (SHP) from diverse causes including renal dysfunction, potassium retaining drugs, Addison's disease, etc. Clinical characteristics of SHP have been addressed in a number of publications. However, electrophysiologic...

  9. Electrophysiological Monitoring of Brain Injury and Recovery after Cardiac Arrest

    Directory of Open Access Journals (Sweden)

    Ruoxian Deng

    2015-10-01

    Full Text Available Reliable prognostic methods for cerebral functional outcome of post cardiac-arrest (CA patients are necessary, especially since therapeutic hypothermia (TH as a standard treatment. Traditional neurophysiological prognostic indicators, such as clinical examination and chemical biomarkers, may result in indecisive outcome predictions and do not directly reflect neuronal activity, though they have remained the mainstay of clinical prognosis. The most recent advances in electrophysiological methods—electroencephalography (EEG pattern, evoked potential (EP and cellular electrophysiological measurement—were developed to complement these deficiencies, and will be examined in this review article. EEG pattern (reactivity and continuity provides real-time and accurate information for early-stage (particularly in the first 24 h hypoxic-ischemic (HI brain injury patients with high sensitivity. However, the signal is easily affected by external stimuli, thus the measurements of EP should be combined with EEG background to validate the predicted neurologic functional result. Cellular electrophysiology, such as multi-unit activity (MUA and local field potentials (LFP, has strong potential for improving prognostication and therapy by offering additional neurophysiologic information to understand the underlying mechanisms of therapeutic methods. Electrophysiology provides reliable and precise prognostication on both global and cellular levels secondary to cerebral injury in cardiac arrest patients treated with TH.

  10. Electrophysiological assessment in patients with Mobius syndrome and clumsiness.

    NARCIS (Netherlands)

    Verzijl, H.T.F.M.; Padberg, G.W.A.M.; Zwarts, M.J.

    2005-01-01

    The authors studied the nature of clumsiness in Mobius syndrome in terms of motor or sensory deficits, and sought to clarify the pathophysiological mechanism of the syndrome. Standardized electrophysiologic studies were conducted, with special emphasis on the long motor and sensory tracts and

  11. A systematic analysis of directional site effects at stations of the Italian Seismic Network to test the role of local topography

    Science.gov (United States)

    Pischiutta, Marta; Cianfarra, Paola; Salvini, Francesco; Cara, Fabrizio; Vannoli, Paola

    2018-03-01

    Directional site effects observed at seismological stations on pronounced relief are analyzed. We investigate the ground motion properties calculating horizontal-to-vertical spectral ratios and horizontal polarization of both ambient vibrations and earthquake records using broadband seismograms of the Italian Seismic Network. We find that a subset of 47 stations with pronounced relief, results in a significant (>2) directional amplification of the horizontal component, with a well defined, site-specific direction of motion. However, the horizontal spectral response of sites is not uniform, varying from an isolated (resonant) frequency peak to a broadband amplification, interesting frequency bands as large as 1-10 Hz in many cases. Using the 47 selected stations, we have tried to establish a relation between directional amplification and topography geometry in a 2D-vision, when applicable, through a morphological analysis of the Digital Elevation Model using Geographic Information Systems. The procedure computes the parameters that characterize the geometry of topographic irregularities (size and slope), in combination with a principal component analysis that automatically yields the orientation of the elongated ridges. In seeking a relation between directional amplification and the surface morphology, we have found that it is impossible to fit the variety of observations with a resonant topography model as well as to identify common features in the ground motion behavior for stations with similar topography typologies. We conclude that, rather than the shape of the topography, local structural complexities and details of the near-surface structure must play a predominant role in controlling ground motion properties at sites with pronounced relief.

  12. Preliminary Sensorimotor and Cardiovascular Results from the Joint Russian and U.S. Pilot Field Test with Planning for the Full Field Test Beginning with the Year Long Intenational Space Station

    Science.gov (United States)

    Reschke, M. F.; Kozlovskaya, I. B.; Tomilovskaya, E. S.; Bloomberg, J. J.; Platts, S. H.; Rukavishnikov, I. V.; Fomina, E. V.; Stenger, M. B.; Lee, S. M. C.; Wood, S. J.; hide

    2014-01-01

    Ongoing collaborative research efforts between NASA's Neuroscience and Cardiovascular Laboratories, and the Institute of Biomedical Problems' (IBMP) Sensory-Motor and Countermeasures Laboratories have been measuring functional sensorimotor, cardiovascular and strength responses following bed rest, dry immersion, short duration (Space Shuttle) and long duration (Mir and International Space Station) space flights. While the unloading paradigms associated with dry immersion and bed rest does serve as acceptable flight analogs, testing of crew responses following the long duration flights previously has not been possible until a minimum of 24 hours after landing. As a result, it is not possible to estimate the nonlinear trend of the early (testing at landing site. By joint agreement, this research effort has been identified as the functional Field Test (FT). For practical reasons the FT has been divided into two phases: the full FT and a preliminary pilot version (PFT) of the FT that is reduced in both length and scope. The primary goal of this research is to determine functional abilities in long duration space flight crews beginning as soon after landing as possible (test in conjunction with postural ataxia testing (quiet stance sway) as well as cardiovascular responses during other functional tasks. In addition to the immediate post-landing collection of data for the full FT, postflight data will be acquired at a minimum of one to three more other times within the 24 hr following landing and continue until functional sensorimotor and cardiovascular responses have returned to preflight normative values. The PFT represents a single trial run comprised of jointly agreed upon subset of tests from the full FT and relies heavily on IBMP's Sensory-Motor and Countermeasures Laboratories for content and implementation. The PFT was first conducted following the September 2013 landing of the Soyuz spacecraft (34S) and again following the landing of Soyuz 35S in November

  13. Software and Hardware Infrastructure for Research in Electrophysiology

    Directory of Open Access Journals (Sweden)

    Roman eMouček

    2014-03-01

    Full Text Available As in other areas of experimental science, operation of electrophysiological laboratory, design and performance of electrophysiological experiments, collection, storage and sharing of experimental data and metadata, analysis and interpretation of these data, and publication of results are time consuming activities. If these activities are well organized and supported by a suitable infrastructure, work efficiency of researchers increases significantly.This article deals with the main concepts, design, and development of software and hardware infrastructure for research in electrophysiology. The described infrastructure has been primarily developed for the needs of neuroinformatics laboratory at the University of West Bohemia, the Czech Republic. However, from the beginning it has been also designed and developed to be open and applicable in laboratories that do similar research.After introducing the laboratory and the whole architectural concept the individual parts of the infrastructure are described. The central element of the software infrastructure is a web-based portal that enables community researchers to store, share, download and search data and metadata from electrophysiological experiments. The data model, domain ontology and usage of semantic web languages and technologies are described. Current data publication policy used in the portal is briefly introduced. The registration of the portal within Neuroscience Information Framework is described. Then the methods used for processing of electrophysiological signals are presented. The specific modifications of these methods introduced by laboratory researches are summarized; the methods are organized into a laboratory workflow. Other parts of the software infrastructure include mobile and offline solutions for data/metadata storing and a hardware stimulator communicating with an EEG amplifier and recording software.

  14. Software and hardware infrastructure for research in electrophysiology.

    Science.gov (United States)

    Mouček, Roman; Ježek, Petr; Vařeka, Lukáš; Rondík, Tomáš; Brůha, Petr; Papež, Václav; Mautner, Pavel; Novotný, Jiří; Prokop, Tomáš; Stěbeták, Jan

    2014-01-01

    As in other areas of experimental science, operation of electrophysiological laboratory, design and performance of electrophysiological experiments, collection, storage and sharing of experimental data and metadata, analysis and interpretation of these data, and publication of results are time consuming activities. If these activities are well organized and supported by a suitable infrastructure, work efficiency of researchers increases significantly. This article deals with the main concepts, design, and development of software and hardware infrastructure for research in electrophysiology. The described infrastructure has been primarily developed for the needs of neuroinformatics laboratory at the University of West Bohemia, the Czech Republic. However, from the beginning it has been also designed and developed to be open and applicable in laboratories that do similar research. After introducing the laboratory and the whole architectural concept the individual parts of the infrastructure are described. The central element of the software infrastructure is a web-based portal that enables community researchers to store, share, download and search data and metadata from electrophysiological experiments. The data model, domain ontology and usage of semantic web languages and technologies are described. Current data publication policy used in the portal is briefly introduced. The registration of the portal within Neuroscience Information Framework is described. Then the methods used for processing of electrophysiological signals are presented. The specific modifications of these methods introduced by laboratory researches are summarized; the methods are organized into a laboratory workflow. Other parts of the software infrastructure include mobile and offline solutions for data/metadata storing and a hardware stimulator communicating with an EEG amplifier and recording software.

  15. Anatomical and Electrophysiological Clustering of Superficial Medial Entorhinal Cortex Interneurons

    Science.gov (United States)

    2017-01-01

    Abstract Local GABAergic interneurons regulate the activity of spatially-modulated principal cells in the medial entorhinal cortex (MEC), mediating stellate-to-stellate connectivity and possibly enabling grid formation via recurrent inhibitory circuitry. Despite the important role interneurons seem to play in the MEC cortical circuit, the combination of low cell counts and functional diversity has made systematic electrophysiological studies of these neurons difficult. For these reasons, there remains a paucity of knowledge on the electrophysiological profiles of superficial MEC interneuron populations. Taking advantage of glutamic acid decarboxylase 2 (GAD2)-IRES-tdTomato and PV-tdTomato transgenic mice, we targeted GABAergic interneurons for whole-cell patch-clamp recordings and characterized their passive membrane features, basic input/output properties and action potential (AP) shape. These electrophysiologically characterized cells were then anatomically reconstructed, with emphasis on axonal projections and pial depth. K-means clustering of interneuron anatomical and electrophysiological data optimally classified a population of 106 interneurons into four distinct clusters. The first cluster is comprised of layer 2- and 3-projecting, slow-firing interneurons. The second cluster is comprised largely of PV+ fast-firing interneurons that project mainly to layers 2 and 3. The third cluster contains layer 1- and 2-projecting interneurons, and the fourth cluster is made up of layer 1-projecting horizontal interneurons. These results, among others, will provide greater understanding of the electrophysiological characteristics of MEC interneurons, help guide future in vivo studies, and may aid in uncovering the mechanism of grid field formation. PMID:29085901

  16. Effects of Motivation and Medication on Electrophysiological Markers of Response Inhibition in Children with Attention-Deficit/Hyperactivity Disorder

    OpenAIRE

    Groom, Madeleine J.; Scerif, Gaia; Liddle, Peter F.; Batty, Martin J.; Liddle, Elizabeth B.; Roberts, Katherine L.; Cahill, John D.; Liotti, Mario; Hollis, Chris

    2010-01-01

    Background Theories of attention-deficit/hyperactivity disorder (ADHD) posit either executive deficits and/or alterations in motivational style and reward processing as core to the disorder. Effects of motivational incentives on electrophysiological correlates of inhibitory control and relationships between motivation and stimulant medication have not been explicitly tested. Methods Children (9?15 years) with combined-type ADHD (n = 28) and matched typically developing children (CTRL) (n = 28...

  17. Developments of space station; Uchu station no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, H. [National Space Development Agency of Japan, Tokyo (Japan)

    1996-03-05

    This paper introduces the Japanese experiment module (JEM) in developing a space station. The JEM consists of systems of a pressurizing section, an exposure section, a pressurizing portion of a supply section, a manipulator and an exposure portion of the supply section. The pressurizing section circulates and controls air so that crews can perform experiments under pressurized environment. The exposure section is a part in which experiments are carried out under exposure environment. The supply section runs between a station and the ground, with required devices loaded on it. The manipulator performs attaching a payload for the exposure section and replaces experimental samples. The JEM undergoes a schedule of fabricating an engineering model, testing for a certification a prototype flight model, and putting the model on a flight. The pressurizing section, exposure section and manipulator are at the stage of system tests. Surveillance of the JEM and control of the experiments are carried out at the Tsukuba Space Center. The Center is composed of a space experiment building, a zero-gravity environment testing building, an astronaut training building, a space station operating building, and a space station testing building. 7 figs., 2 tabs.

  18. Effects of aspartame on the evaluation of electrophysiological responses in Wistar albino rats

    Directory of Open Access Journals (Sweden)

    Arbind Kumar Choudhary

    2016-07-01

    Full Text Available Aspartame is a non-nutritive sweetener that is used predominantly in various ‘diet’ and ‘low-calorie’ products, such as beverages, instant breakfasts, desserts, breath mints, sugar-free chewing gum, vitamins, and pharmaceuticals, consumed by millions of people who are attempting weight loss, young adults and diabetic persons. On a weight basis, the metabolism of aspartame generates approximately 50% phenylalanine, 40% aspartic acid and 10% methanol. The detailed mechanisms of the effects of aspartame on the electrophysiological response are still unclear; therefore, this study was designed to clarify whether longer-term aspartame consumption has any effect on the electrophysiological response in Wistar albino rats. The oral administration of aspartame in a safe dose of 40 mg/kg bodyweight/day (as recommended by EFSA, 2012 was tested in Wistar albino rats for a longer period (90 days. Electrophysiological responses, including heart rate variability (HRV and electroencephalogram (EEG pattern, were assessed in a folate-deficient animal model along with control animals using BIOPAC and EEG equipment (model RMS EEG–24 brain new-plus: RMS – Recorder and Medicare systems. In this study, the folate-deficient animal model was used to mimic human methanol metabolism in rats. After 90 days of aspartame treatment, a significant alteration was observable in the time domain [Mean RR (ms SDNN (ms RMSSD (ms PNN50 (%] and the frequency domain [LF, HF, and LF/HF ratio] with significantly impaired frequency and amplitude of the fronto-parietal and occipital EEG waves at p ≤ 0.05. The results of this study clearly indicate that the oral consumption of aspartame reduced HRV, with sympathetic dominance and loss of vagal tone, and altered sympathovagal activity along with impairment of learning and memory, showing an additional effect on health within this study duration. The aspartame metabolites methanol and formaldehyde may be the causative factors

  19. Clinical, neuropsychological, and pre-stimulus dorsomedial thalamic nucleus electrophysiological data in deep brain stimulation patients

    Directory of Open Access Journals (Sweden)

    Catherine M. Sweeney-Reed

    2016-09-01

    Full Text Available The data presented here comprise clinical, neuropsychological, and intrathalamic electrophysiological data from 7 patients with pharmacoresistant focal epilepsy and are related to the article “Pre-stimulus thalamic theta power predicts human memory formation” C.M. Sweeney-Reed, T. Zaehle, J. Voges, F.C. Schmitt, L. Buentjen, K. Kopitzki, et al. (2016 [1]. The patients participated in a memory paradigm after receiving electrodes implanted in the DMTN due to the surgical approach taken in electrode insertion for deep brain stimulation of the anterior thalamic nucleus. Epilepsy duration and pre-operative neuropsychological tests provide an indication of the profile of patients receiving intrathalamic electrode implantation and the memory capabilities in such a patient group. The electrophysiological data were recorded from the right DMTN preceding stimulus presentation during intentional memory encoding. The patients viewed a series of photographic scenes, which they judged as indoors or outdoors. The 900 ms epochs prior to stimulus presentation were labeled as preceding successful or unsuccessful subsequent memory formation according to a subsequent memory test for the items. The difference between theta power preceding successful versus unsuccessful subsequent memory formation is shown against time for each patient individually. Keywords: Memory encoding, Dorsomedial thalamic nucleus, Pre-stimulus theta

  20. Functional, electrophysiological recoveries of rats with sciatic nerve lesions following transplantation of elongated DRG cells.

    Science.gov (United States)

    Dayawansa, Samantha; Zhang, Jun; Shih, Chung-Hsuan; Tharakan, Binu; Huang, Jason H

    2016-04-01

    Functional data are essential when confirming the efficacy of elongated dorsal root ganglia (DRG) cells as a substitute for autografting. We present the quantitative functional motor, electrophysiological findings of engineered DRG recipients for the first time. Elongated DRG neurons and autografts were transplanted to bridge 1-cm sciatic nerve lesions of Sprague Dawley (SD) rats. Motor recoveries of elongated DRG recipients (n=9), autograft recipients (n=9), unrepaired rats (n=9) and intact rats (n=6) were investigated using the angle board challenge test following 16 weeks of recovery. Electrophysiology studies were conducted to assess the functional recovery at 16 weeks. In addition, elongated DRGs were subjected to histology assessments. At threshold levels (35° angle) of the angle board challenge test, the autograft recipients', DRG recipients' and unrepaired group's performances were equal to each other and were less than the intact group (pDRG recipients' performance was similar to both the intact group and the autograft nerve recipients, and was better (pDRG constructs had intact signal transmission when recorded over the lesion, while the unrepaired rats did not. It was observed that elongated DRG neurons closely resembled an autograft during histological assessments. Performances of autograft and elongated DRG construct recipients were similar. Elongated DRG neurons should be further investigated as a substitute for autografting.

  1. Clinical, Electrophysiological, and Serological Evaluation of Patients with Cramp-Fasciculation Syndrome.

    Science.gov (United States)

    Poyraz, Mürüvvet; Matur, Zeliha; Aysal, Fikret; Tüzün, Erdem; Hanoğlu, Lütfü; Öge, A Emre

    2017-06-01

    Cramp-fasciculation syndrome (CFS) is a rare peripheral nerve hyperexcitability syndrome. There are only a few reports on clinical and serological profile of a CFS cohort that was followed up by a single outpatient clinic. Clinical, electrophysiological, and serological features of 6 CFS patients (5 men, 1 woman; 27-65 years old) were investigated. All patients presented with cramps, fasciculations, muscle pain, and autonomic symptoms, and 2 also reported numbness and burning sensation in limbs, suggestive of neuropathic pain. Antibodies to uncharacterized voltage-gated potassium channel (VGKC)-complex proteins were found in 2 patients and to contactin-associated protein-like 2 (CASPR2) in 1 patient. None of the patients had a tumor. Most of the patients revealed prolonged after-discharges following tibial nerve stimulation. Nerve conduction studies and R-R interval variability tests were normal, whereas sympathetic skin responses were increased in amplitude in 3 seronegative patients. Five patients showed favorable response to carbamazepine or pregabalin treatment, whereas 1 VGKC-antibody-positive patient was resistant to carbamazepine and immunosuppressant treatment. Neuropathic pain and VGKC-complex antibodies may be encountered in CFS patients. Although autonomic symptoms are commonly found in CFS, routine autonomic system tests which are done in electrophysiology laboratories might yield normal results.

  2. Reference Climatological Stations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Reference Climatological Stations (RCS) network represents the first effort by NOAA to create and maintain a nationwide network of stations located only in areas...

  3. Streamflow Gaging Stations

    Data.gov (United States)

    Department of Homeland Security — This map layer shows selected streamflow gaging stations of the United States, Puerto Rico, and the U.S. Virgin Islands, in 2013. Gaging stations, or gages, measure...

  4. Fire Stations - 2007

    Data.gov (United States)

    Kansas Data Access and Support Center — Fire Station Locations in Kansas Any location where fire fighters are stationed at or based out of, or where equipment that such personnel use in carrying out their...

  5. Hammond Bay Biological Station

    Data.gov (United States)

    Federal Laboratory Consortium — Hammond Bay Biological Station (HBBS), located near Millersburg, Michigan, is a field station of the USGS Great Lakes Science Center (GLSC). HBBS was established by...

  6. Water Level Station History

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Images contain station history information for 175 stations in the National Water Level Observation Network (NWLON). The NWLON is a network of long-term,...

  7. Weather Radar Stations

    Data.gov (United States)

    Department of Homeland Security — These data represent Next-Generation Radar (NEXRAD) and Terminal Doppler Weather Radar (TDWR) weather radar stations within the US. The NEXRAD radar stations are...

  8. Big Game Reporting Stations

    Data.gov (United States)

    Vermont Center for Geographic Information — Point locations of big game reporting stations. Big game reporting stations are places where hunters can legally report harvested deer, bear, or turkey. These are...

  9. Ocean Station Vessel

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Ocean Station Vessels (OSV) or Weather Ships captured atmospheric conditions while being stationed continuously in a single location. While While most of the...

  10. Fire Stations - 2009

    Data.gov (United States)

    Kansas Data Access and Support Center — Fire Stations in Kansas Any location where fire fighters are stationed or based out of, or where equipment that such personnel use in carrying out their jobs is...

  11. Newport Research Station

    Data.gov (United States)

    Federal Laboratory Consortium — The Newport Research Station is the Center's only ocean-port research facility. This station is located at Oregon State University's Hatfield Marine Science Center,...

  12. Electrophysiological and biochemical studies of slow responses to serotonin and dopamine of snail identified neurons. Mediating role of the cyclic AMP

    International Nuclear Information System (INIS)

    Deterre, Philippe

    1983-01-01

    In this research thesis, the electrophysiological study of slow incoming currents induced in some identified neurons of the Helix aspersa snail by serotonin and dopamine shows that they are associated with a decrease of a potassium conductance involved in the modulation of the action potential duration. By means of enzymatic tests performed on a single cell, and of electrophysiological experiments, the author shows that the cyclic AMP is an intracellular mediator involved in the genesis of these slow responses. Moreover, the obtained results show that serotonin and dopamine act by binding to specific receptors, and that these receptors activate the adenylate-cyclase through a GTP binding protein [fr

  13. Space Station personal hygiene study

    Science.gov (United States)

    Prejean, Stephen E.; Booher, Cletis R.

    1986-01-01

    A personal hygiene system is currently under development for Space Station application that will provide capabilities equivalent to those found on earth. This paper addresses the study approach for specifying both primary and contingency personal hygiene systems and provisions for specified growth. Topics covered are system definition and subsystem descriptions. Subsystem interfaces are explored to determine which concurrent NASA study efforts must be monitored during future design phases to stay up-to-date on critical Space Station parameters. A design concept for a three (3) compartment personal hygiene facility is included as a baseline for planned test and verification activities.

  14. CDIP Station Data Collection - All Stations

    Data.gov (United States)

    Scripps Institution of Oceanography, UC San Diego — The Coastal Data Information Program's station data collection consists of all publicly-released coastal environment measurements taken over the program's history, a...

  15. Electrophysiological indices of response inhibition in a Go/NoGo task predict self-control in a social context.

    Directory of Open Access Journals (Sweden)

    Kyle Nash

    Full Text Available Recent research demonstrates that response inhibition-a core executive function-may subserve self-regulation and self-control. However, it is unclear whether response inhibition also predicts self-control in the multifaceted, high-level phenomena of social decision-making. Here we examined whether electrophysiological indices of response inhibition would predict self-control in a social context. Electroencephalography was recorded as participants completed a widely used Go/NoGo task (the cued Continuous Performance Test. Participants then interacted with a partner in an economic exchange game that requires self-control. Results demonstrated that greater NoGo-Anteriorization and larger NoGo-P300 peak amplitudes-two established electrophysiological indices of response inhibition-both predicted more self-control in this social game. These findings support continued integration of executive function and self-regulation and help extend prior research into social decision-making processes.

  16. Electrophysiological Evaluation of Oropharyngeal Dysphagia in Parkinson’s Disease

    Science.gov (United States)

    Ertekin, Cumhur

    2014-01-01

    Parkinson’s disease (PD) is a chronic, neurodegenerative movement disorder that typically affects elderly patients. Swallowing disorders are highly prevalent in PD and can have grave consequences, including pneumonia, malnutrition, dehydration and mortality. Neurogenic dysphagia in PD can manifest with both overt clinical symptoms or silent dysphagia. Regardless, early diagnosis and objective follow-up of dysphagia in PD is crucial for timely and appropriate care for these patients. In this review, we provide a comprehensive summary of the electrophysiological methods that can be used to objectively evaluate dysphagia in PD. We discuss the electrophysiological abnormalities that can be observed in PD, their clinical correlates and the pathophysiology underlying these findings. PMID:25360228

  17. Subthalamic stimulation: toward a simplification of the electrophysiological procedure.

    Science.gov (United States)

    Fetter, Damien; Derrey, Stephane; Lefaucheur, Romain; Borden, Alaina; Wallon, David; Chastan, Nathalie; Maltete, David

    2016-06-01

    The aim of the present study was to assess the consequences of a simplification of the electrophysiological procedure on the post-operative clinical outcome after subthalamic nucleus implantation in Parkinson disease. Microelectrode recordings were performed on 5 parallel trajectories in group 1 and less than 5 trajectories in group 2. Clinical evaluations were performed 1 month before and 6 months after surgery. After surgery, the UPDRS III score in the off-drug/on-stimulation and on-drug/on-stimulation conditions significantly improved by 66,9% and 82%, respectively in group 1, and by 65.8% and 82.3% in group 2 (P<0.05). Meanwhile, the total number of words (P<0.05) significantly decreased for fluency tasks in both groups. Motor disability improvement and medication reduction were similar in both groups. Our results suggest that the electrophysiological procedure should be simplified as the team's experience increases.

  18. Resuscitation great. Luigi Galvani and the foundations of electrophysiology.

    Science.gov (United States)

    Cajavilca, Christian; Varon, Joseph; Sternbach, George L

    2009-02-01

    Luigi Galvani became one of the greatest scientists of the 18th century with his research and the development of his theory on animal electricity. His work was appreciated by many scientists. Nevertheless, it gave rise to one of the most passionate scientific debates in history when Alessandro Volta postulated that Galvani had confused intrinsic animal electricity with small currents produced by metals. This debate would result in the creation of electrophysiology, electromagnetism, electrochemistry and the electrical battery. Galvani responded to each of the postulated theories of Volta giving irrefutable proof of the involvement of electricity in the contraction of muscles. However, his work was subsequently abandoned and silenced for many years but his ideas and theories were finally confirmed by the creation of new instruments and the interest of new scientists who helped position Galvani as the father of electrophysiology.

  19. Breadboard Amplifier: Building and Using Simple Electrophysiology Equipment.

    Science.gov (United States)

    Crisp, Kevin M; Lin, Hunter; Prosper, Issa

    2016-01-01

    Electrophysiology is a valuable skill for the neuroscientist, but the learning curve for students can be steep. Here we describe a very simple electromyography (EMG) amplifier that can be built from scratch by students with no electronics experience in about 30 minutes, making it ideal for incorporating into a laboratory activity. With few parts and no adjustments except the gain, students can begin physiology experiments quickly while having the satisfaction of having built the equipment themselves. Because the output of the circuit goes to a computer sound card, students can listen to electrophysiological activity as they see it on the computer screen, a feature many of our students greatly appreciated. Various applications are discussed, including dual channel recording, using streaming media platforms with remote lab partners and acquiring data in the field on a smart phone. Our students reported that they enjoyed being able to build a working device and using it to record from their own muscles.

  20. Electrophysiological study for comparing the effect of biological activity between type A botulinum toxins in rat gastrocnemius muscle.

    Science.gov (United States)

    Kim, C-S; Jang, W S; Son, I P; Nam, S H; Kim, Y I; Park, K Y; Kim, B J; Kim, M N

    2013-09-01

    New cosmetic applications and products based on the effects of botulinum toxin (BTX) treatment have stimulated demand for this class of natural compounds. This demand generates the need for appropriate standardized protocols to test and compare the effectiveness of new BTX preparations. Based on the previously described electrophysiological methods, we measured and compared the inhibitory effects of two BTX type A (BTX-A) preparations on neuromuscular transmission through split-body test. The effectiveness was evaluated in terms of the compound muscle action potential (CMAP) and conduction velocity after BTX-A injection. We used a split-body method to compare two different BTX-As in the rat. Based on the changes in the CMAP, the two different BTX-As induced paralytic effect on the rat tibialis anterior muscle. However, the two different BTX-A preparations did not differ significantly in effectiveness and did not induce a delay in conduction velocity. The new BTX-A preparation used in this electrophysiological study had similar effect compared with the previously marketed BTX-A.[AQ: Please approve the edits made to the sentence "The new BTX-A preparation…") We propose that a split-body electrophysiological protocol will be useful in establishing the comparative effectiveness of new BTX products.

  1. Computational Intelligence Techniques for Electro-Physiological Data Analysis

    OpenAIRE

    Riera Sardà, Alexandre

    2012-01-01

    This work contains the efforts I have made in the last years in the field of Electrophysiological data analysis. Most of the work has been done at Starlab Barcelona S.L. and part of it at the Neurodynamics Laboratory of the Department of Psychiatry and Clinical Psychobiology of the University of Barcelona. The main work deals with the analysis of electroencephalography (EEG) signals, although other signals, such as electrocardiography (ECG), electroculography (EOG) and electromiography (EMG) ...

  2. High throughput electrophysiology: new perspectives for ion channel drug discovery

    DEFF Research Database (Denmark)

    Willumsen, Niels J; Bech, Morten; Olesen, Søren-Peter

    2003-01-01

    . A cornerstone in current drug discovery is high throughput screening assays which allow examination of the activity of specific ion channels though only to a limited extent. Conventional patch clamp remains the sole technique with sufficiently high time resolution and sensitivity required for precise and direct....... The introduction of new powerful HTS electrophysiological techniques is predicted to cause a revolution in ion channel drug discovery....

  3. A facility for training Space Station astronauts

    Science.gov (United States)

    Hajare, Ankur R.; Schmidt, James R.

    1992-01-01

    The Space Station Training Facility (SSTF) will be the primary facility for training the Space Station Freedom astronauts and the Space Station Control Center ground support personnel. Conceptually, the SSTF will consist of two parts: a Student Environment and an Author Environment. The Student Environment will contain trainers, instructor stations, computers and other equipment necessary for training. The Author Environment will contain the systems that will be used to manage, develop, integrate, test and verify, operate and maintain the equipment and software in the Student Environment.

  4. The Miksova water power station

    International Nuclear Information System (INIS)

    2005-01-01

    Miksova water power station produced total of about 7,161,342 MWh of electricity in its 40 years of activity. According to its functionality, the Miksova pumped storage station (Miksova II) the upper reservoir of which was built from 1963 to 1966 on the Benovsky stream, was an interesting hydro-energy construction. The lower reservoir was formed by the enlarged discharge channel of the Miksova water power station. This power station was a pilot project, at which pumping reversible turbines and other mechanical-technical equipment for hydro power stations were tested, especially for the future construction of PVE Ruzin and Liptovska Mara. A turbine set with a diagonal reversible turbine and an installed capacity of 2.6 MW, which had an operational capacity of 11.2 m 3 .s -1 in a turbine mode of operation and using a head of 22 to 28 m, was installed in the machine room. It pumped 8.8 m 3 .s -1 of water with a power input of 3.1 MW in a pumping mode of operation. During the period of its operation from 1971 to 1984, pumping hydro power station Miksova II produced a total of 13,042 MWh of electricity in total, but by testing reversible turbines and the simulation of some special hydraulic phenomena, this power station lost its importance as low-efficiency source, stopped working and its technological equipment was demounted. Experiences from its construction and from its few years of operation were later used during the construction of our pumping hydro power stations. Prolonging its operating period should help with the installation of a bigger basin on the inflow, from which a greater amount of water could be used for the generation of electrical power in turbine mode of operation

  5. Technical evaluation report TMI action - NUREG-0737 (II.D.1) relief and safety valve testing for Clinton Power Station Unit 1. (Docket No. 50-461)

    International Nuclear Information System (INIS)

    Burr, T.K.; Magleby, H.L.

    1985-05-01

    Light water reactors operators have experienced a number of occurrences of improper performance by safety and relief valves installed in their primary coolant systems. Because of this, the authors of NUREG-0578 (TMI-2 Lessons Learned Task Force Status Report and Short-Term Recommendations) recommended that programs be developed and completed which would reevaluate the performance capabilities of BWR safety and relief valves. This report has examined the response of the Licensee for the Clinton Power Station, Unit 1 to the requirements of NUREG-0578 and subsequently NUREG-0737 and finds that the Licensee has provided an acceptable response, reconfirming that the General Design Criteria 14, 15 and 30 of Appendix A to 10 CFR-50 have been met

  6. Shippingport Station decommissioning project overview

    International Nuclear Information System (INIS)

    Schreiber, J.J.

    1985-01-01

    The U.S. Department of Energy is in the process of decommissioning the Shippingport Atomic Power Station located on the Ohio River, 30 miles northwest of Pittsburgh, Pennsylvania. The Shippingport Station is the first commercial size nuclear power plant to undergo decommissioning in the United Staes. The plant is located on approximately 7 acres of land owned by the Duquesne Light Company (DLC) and leased to the U.S. Government. DLC operates two nuclear power plants, Beaver Valley 1 and 2, located immediately adjacent to the site and the Bruce Mansfield coal-fired power plant is also within the immediate area. The Station was shutdown in October, 1982. Defueling operations began in 1983 and were completed by September, 1984. The Shippingport Station consists of a 275' x 60' fuel handling building containing the reactor containment chamber, the service building, the turbine building, the radioactive waste processing building, the administration building and other smaller support buildings. The Station has four coolant loops and most of the containment structures are located below grade. Structures owned by the U.S. Government including the fuel handling building, service building, contaminated equipment room, the boiler chambers, the radioactive waste processing building and the decontamination and laydown buildings will be dismantled and removed to 3 feet below grade. The area will then be filled with clean soil and graded. The turbine building, testing and training building and the administration building are owned by DLC and will remain

  7. Electrophysiological response of chicken's jejunal epithelium to increasing levels of T-2 toxin.

    Science.gov (United States)

    Yunus, Agha Waqar; Kröger, Susan; Tichy, Alexander; Zentek, Jürgen; Böhm, Josef

    2013-02-01

    The present investigations were conducted to test the effects of T-2 toxin on electrophysiological variables of jejunal epithelium of chicken. Jejunal segments of broilers were monitored in Ussing chambers in the presence of T-2 toxin at the levels of 0 (negative control), 0 (methanol/vehicle control), 0.1, 1, 5, and 10 μg/ml of buffer. T-2 toxin did not affect basal values of short circuit current (I(sc)), transmural potential difference, or tissue conductivity in the jejunal epithelium. T-2 toxin also did not statistically affect glucose-induced electrophysiological variables during the first 3 min of glucose induction. Compared to the vehicle control, the ouabain-sensitive I(sc) was negatively affected (P = 0.008) only under 5 μg of T-2 toxin/ml. Increasing levels of T-2 toxin negatively affected the ouabain-sensitive I(sc) in a cubic (P = 0.007) fashion. These data indicate that acute exposure to moderate levels of T-2 toxin may progressively impair the cation gradient across the jejunal epithelium.

  8. Maternal mobile phone exposure alters intrinsic electrophysiological properties of CA1 pyramidal neurons in rat offspring.

    Science.gov (United States)

    Razavinasab, Moazamehosadat; Moazzami, Kasra; Shabani, Mohammad

    2016-06-01

    Some studies have shown that exposure to electromagnetic field (EMF) may result in structural damage to neurons. In this study, we have elucidated the alteration in the hippocampal function of offspring Wistar rats (n = 8 rats in each group) that were chronically exposed to mobile phones during their gestational period by applying behavioral, histological, and electrophysiological tests. Rats in the EMF group were exposed to 900 MHz pulsed-EMF irradiation for 6 h/day. Whole cell recordings in hippocampal pyramidal cells in the mobile phone groups did show a decrease in neuronal excitability. Mobile phone exposure was mostly associated with a decrease in the number of action potentials fired in spontaneous activity and in response to current injection in both male and female groups. There was an increase in the amplitude of the afterhyperpolarization (AHP) in mobile phone rats compared with the control. The results of the passive avoidance and Morris water maze assessment of learning and memory performance showed that phone exposure significantly altered learning acquisition and memory retention in male and female rats compared with the control rats. Light microscopy study of brain sections of the control and mobile phone-exposed rats showed normal morphology.Our results suggest that exposure to mobile phones adversely affects the cognitive performance of both female and male offspring rats using behavioral and electrophysiological techniques. © The Author(s) 2014.

  9. An integrated domain specific language for post-processing and visualizing electrophysiological signals in Java.

    Science.gov (United States)

    Strasser, T; Peters, T; Jagle, H; Zrenner, E; Wilke, R

    2010-01-01

    Electrophysiology of vision - especially the electroretinogram (ERG) - is used as a non-invasive way for functional testing of the visual system. The ERG is a combined electrical response generated by neural and non-neuronal cells in the retina in response to light stimulation. This response can be recorded and used for diagnosis of numerous disorders. For both clinical practice and clinical trials it is important to process those signals in an accurate and fast way and to provide the results as structured, consistent reports. Therefore, we developed a freely available and open-source framework in Java (http://www.eye.uni-tuebingen.de/project/idsI4sigproc). The framework is focused on an easy integration with existing applications. By leveraging well-established software patterns like pipes-and-filters and fluent interfaces as well as by designing the application programming interfaces (API) as an integrated domain specific language (DSL) the overall framework provides a smooth learning curve. Additionally, it already contains several processing methods and visualization features and can be extended easily by implementing the provided interfaces. In this way, not only can new processing methods be added but the framework can also be adopted for other areas of signal processing. This article describes in detail the structure and implementation of the framework and demonstrate its application through the software package used in clinical practice and clinical trials at the University Eye Hospital Tuebingen one of the largest departments in the field of visual electrophysiology in Europe.

  10. Scopolamine Reduces Electrophysiological Indices of Distractor Suppression: Evidence from a Contingent Capture Task

    Directory of Open Access Journals (Sweden)

    Inga Laube

    2017-12-01

    Full Text Available Limited resources for the in-depth processing of external stimuli make it necessary to select only relevant information from our surroundings and to ignore irrelevant stimuli. Attentional mechanisms facilitate this selection via top-down modulation of stimulus representations in the brain. Previous research has indicated that acetylcholine (ACh modulates this influence of attention on stimulus processing. However, the role of muscarinic receptors as well as the specific mechanism of cholinergic modulation remains unclear. Here we investigated the influence of ACh on feature-based, top-down control of stimulus processing via muscarinic receptors by using a contingent capture paradigm which specifically tests attentional shifts toward uninformative cue stimuli which display one of the target defining features In a double-blind, placebo controlled study we measured the impact of the muscarinic receptor antagonist scopolamine on behavioral and electrophysiological measures of contingent attentional capture. The results demonstrated all the signs of functional contingent capture, i.e., attentional shifts toward cued locations reflected in increased amplitudes of N1 and N2Pc components, under placebo conditions. However, scopolamine did not affect behavioral or electrophysiological measures of contingent capture. Instead, scopolamine reduced the amplitude of the distractor-evoked Pd component which has recently been associated with active suppression of irrelevant distractor information. The findings suggest a general cholinergic modulation of top-down control during distractor processing.

  11. Planar patch clamp: advances in electrophysiology.

    Science.gov (United States)

    Brüggemann, Andrea; Farre, Cecilia; Haarmann, Claudia; Haythornthwaite, Ali; Kreir, Mohamed; Stoelzle, Sonja; George, Michael; Fertig, Niels

    2008-01-01

    Ion channels have gained increased interest as therapeutic targets over recent years, since a growing number of human and animal diseases have been attributed to defects in ion channel function. Potassium channels are the largest and most diverse family of ion channels. Pharmaceutical agents such as Glibenclamide, an inhibitor of K(ATP) channel activity which promotes insulin release, have been successfully sold on the market for many years. So far, only a small group of the known ion channels have been addressed as potential drug targets. The functional testing of drugs on these ion channels has always been the bottleneck in the development of these types of pharmaceutical compounds.New generations of automated patch clamp screening platforms allow a higher throughput for drug testing and widen this bottleneck. Due to their planar chip design not only is a higher throughput achieved, but new applications have also become possible. One of the advantages of planar patch clamp is the possibility of perfusing the intracellular side of the membrane during a patch clamp experiment in the whole-cell configuration. Furthermore, the extracellular membrane remains accessible for compound application during the experiment.Internal perfusion can be used not only for patch clamp experiments with cell membranes, but also for those with artificial lipid bilayers. In this chapter we describe how internal perfusion can be applied to potassium channels expressed in Jurkat cells, and to Gramicidin channels reconstituted in a lipid bilayer.

  12. Non-Coop Station History

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Station history documentation for stations outside the US Cooperative Observer network. Primarily National Weather Service stations assigned WBAN station IDs. Other...

  13. The Role of Non-Destructive Testing in Test-Reactor Operation at the National Reactor Testing Station; Role des Essais Non Destructifs dans l'Exploitation des Reacteurs d'Essai au Centre National d'Essais de Reacteurs; Rol' nedestruktivnykh ispytanij pri ehkspluatatsii ispytatel'nykh reaktorov na natsional'noj stantsii po ispytaniyam reaktorov; Papel de los Metodos No Destructivos en la Explotacion de los Reactores de la National Reactor Testing Station

    Energy Technology Data Exchange (ETDEWEB)

    Francis, W. C.; Brown, E. S.; Burdick, E. E.; Gibson, G. W.; Tingey, F. H. [Phillips Petroleum Company, Atomic Energy Division, Idaho Falls, Idaho (United States)

    1965-10-15

    The huge investment (well over $100 000 000) in the Nuclear Test Reactors at the National Reactor Testing Station and the need to operate them safely requires the highest order of quality control for reactor and test components, especially for fuel and control elements. Non-destructive testing has, therefore, assumed a very vital role in establishing the quality of these components before their use in the Test Reactors. Although many of these non-destructive tests follow well-established procedures, many unique techniques have been developed and new uses made of conventional equipment. Ultrasonic techniques have long been used at this site for detecting voids, non-bonding and internal cracking. More recently this work has been extended to the automated scanning of curved plates and to the inspection of irradiated fuel plates in the storage canals. A very interesting work has been the application of the ultrasonic technique to the detection of brittle core fracture which may occur in forming operations. A gamma-scanning technique to establish the U{sup 235} content of fuel elements has proved so reliable that it is the basis for assessing financial penalties for out-of-specification material. Radiographs of fuel plates provide core dimensions and, with densitometer scans, determine fuel distribution. Radiographing of welds is standard procedure for reactor and test loop components. Burnup of fuel and poison in test specimens may be determined each reactor cycle by the use of the Advanced Reactivity Measurement Facility (ARMF). A somewhat unusual application for a critical facility is the measurement of the boron content of fuel in the Engineering Test Reactor Critical Facility (ETRC). Eddy-current and mechanical probing of fuel-plate spacing and eddy-current gauging of oxide film thickness (corrosion) on irradiated plates have given excellent results. Additional techniques, which have proved valuable, include liquid penetrant inspection and liquid nitrogen tests for

  14. Late-onset Becker muscular dystrophy: Refining the clinical features and electrophysiological findings.

    Science.gov (United States)

    Beltran Papsdorf, Tania; Howard, James F; Chahin, Nizar

    2015-11-01

    The aim of this study was to characterize a unique distribution of muscle involvement in sporadic Becker muscle dystrophy (BMD). Retrospective chart review, clinical examination, electrophysiological studies, cardiac testing, and genetic testing were performed in 5 patients. Predominant weakness and atrophy of biceps brachii, hip adduction, and quadriceps muscles was noted along with calf and extensor forearm hypertrophy. Finger flexor muscles were severely weak in 3 of 5 patients, a feature that could lead to a misdiagnosis of inclusion body myositis. Creatinine kinase was only mildly elevated in most patients. Electromyography was abnormal in all patients. Muscle biopsy in 1 patient demonstrated normal immunostaining for dystrophin. We found a unique and uniform distribution of muscle involvement in 5 sporadic cases of BMD. Recognizing these features is important for differentiating it from other myopathies that may have similar features and avoids unnecessary invasive procedures such as muscle biopsy. © 2015 Wiley Periodicals, Inc.

  15. Mapping of electrophysiological response to transcranial infrared laser stimulation on the human brain in vivo measured by electroencephalography (Conference Presentation)

    Science.gov (United States)

    Wang, Xinlong; Reddy, Divya Dhandapani; Gonzalez-Lima, F.; Liu, Hanli

    2017-02-01

    Transcranial infrared laser stimulation (TILS) is a non-destructive and non-thermal photobiomodulation therapy or process on the human brain; TILS uses infrared light from lasers or LEDs and has gained increased recognition for its beneficial effects on a variety of neurological and psychological conditions. While the mechanism of TILS has been assumed to stem from cytochrome-c-oxidase (CCO), which is the last enzyme in the electron transportation chain and is the primary photoacceptor, no literature is found to report electrophysiological response to TILS. In this study, a 64-channel electroencephalography (EEG) system was employed to monitor electrophysiological activities from 15 healthy human participants before, during and after TILS. A placebo experimental protocol was also applied for rigorous comparison. After recording a 3-minute baseline, we applied a 1064-nm laser with a power of 3.5W on the right forehead of each human participant for 8 minutes, followed by a 5-minute recovery period. In 64-channel EEG data analysis, we utilized several methods (root mean square, principal component analysis followed by independent component analysis, permutation conditional mutual information, and time-frequency wavelet analysis) to reveal differences in electrophysiological response to TILS between the stimulated versus placebo group. The analyzed results were further investigated using general linear model and paired t-test to reveal statistically meaningful responses induced by TILS. Moreover, this study will provide spatial mapping of human electrophysiological and possibly neural network responses to TILS for first time, indicating the potential of EEG to be an effective method for monitoring neurological improvement induced by TILS.

  16. Tests on instrumentation and control systems important to safety in nuclear power stations. Systempruefung der leittechnischen Einrichtungen des Sicherheitssystems in Kernkraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    1985-01-01

    The rule applies to the reactor protection system, to the protection and state boundaries, to control devices important to safety, and to danger alarms of the classes S and I. The system inspection of the control devices of the safety system comprises in-service testing and recurrent testing.

  17. Amtrak Rail Stations (National)

    Data.gov (United States)

    Department of Transportation — Updated database of the Federal Railroad Administration's (FRA) Amtrak Station database. This database is a geographic data set containing Amtrak intercity railroad...

  18. Cooperative Station History Forms

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Various forms, photographs and correspondence documenting the history of Cooperative station instrumentation, location changes, inspections, and...

  19. Electrophysiological assessment of the effects of obstructive sleep apnea on cognition.

    Directory of Open Access Journals (Sweden)

    Ethem Gelir

    Full Text Available We used electrophysiological measures to investigate the effects of obstructive sleep apnea on attention, learning, and memory. Thirty subjects (OSA group, n = 15, control group n = 15 participated in n-back tests, accompanied by P300 recordings, to investigate working memory and attention. The mirror-drawing test was used to study procedural memory, and the trail-making test (TMT was used to evaluate divided attention and executive function. No significant group difference in reaction time was found in the 0-back and 1-back tests. In the 2-back test, reaction times of patients were longer than those of the control group. No P300 wave was obtained in the OSA group in any (0-, 1-, or 2-back n-back test. In contrast, in the control group, significant P300 waves were recorded except for the 2-back test. The mirror-drawing scores were unaffected by sleep apnea. There was no difference between groups in the TMT-A test on any of the trials. Although no group difference was found in the first or second trials of the TMT-B test, OSA patients were less successful in learning on the third trial. According to our study results, OSA affects attention and executive function adversely however, we could not detect a significant effect on working or procedural memory.

  20. Safety Evaluation Report, pump and valve inservice testing program, Yankee Rowe Nuclear Power Station (Docket No. 50-29). Revision 1

    International Nuclear Information System (INIS)

    Ransom, C.B.; Rockhold, H.C.

    1985-10-01

    The staff reviewed the Yankee Rowe IST program submittal dated October 2, 1981 and evaluated the proposed tests for compliance with the requirements of the ASME Boiler and Pressure Vessel Code, Section XI, 1977 Edition, through the Summer of 1978 Addenda. Those items not in compliance were discussed in a working session with Yankee Atomic Electric Company personnel, USNRC representatives, and EG and G Idaho reviewers on June 22, 1982. The evaluations presented in this SER of the Yankee Rowe pump and valve inservice testing program and the associated relief requests are those of the NRC staff. These findings apply only to component testing

  1. Transceiver for Space Station Freedom

    Science.gov (United States)

    Fitzmaurice, M.; Bruno, R.

    1990-07-01

    This paper describes the design of the Laser Communication Transceiver (LCT) system which was planned to be flight tested as an attached payload on Space Station Freedom. The objective in building and flight-testing the LCT is to perform a broad class of tests addressing the critical aspects of space-based optical communications systems, providing a base of experience for applying laser communications technology toward future communications needs. The LCT's functional and performance requirements and capabilities with respect to acquisition, spatial tracking and pointing, communications, and attitude determination are discussed.

  2. The APS optics topography station

    International Nuclear Information System (INIS)

    Krasnicki, S.

    1996-01-01

    An in-house station for topographic testing of x-ray optical elements for the Advanced Photon Source experimental beamlines was set up by the Experimental Facilities Division of Argonne National Laboratory. A new double-crystal x-ray diffractometer was designed and built keeping in mind the need for testing large crystals possibly attached to cooling manifolds and lines. A short description of the new facility is given. The instrument performance fully satisfies imposed requirements, and the machine was successfully used for testing several silicon and diamond crystals

  3. The amygdala as a neurobiological target for ghrelin in rats: neuroanatomical, electrophysiological and behavioral evidence.

    Directory of Open Access Journals (Sweden)

    Mayte Alvarez-Crespo

    Full Text Available Here, we sought to demonstrate that the orexigenic circulating hormone, ghrelin, is able to exert neurobiological effects (including those linked to feeding control at the level of the amygdala, involving neuroanatomical, electrophysiological and behavioural studies. We found that ghrelin receptors (GHS-R are densely expressed in several subnuclei of the amygdala, notably in ventrolateral (LaVL and ventromedial (LaVM parts of the lateral amygdaloid nucleus. Using whole-cell patch clamp electrophysiology to record from cells in the lateral amygdaloid nucleus, we found that ghrelin reduced the frequency of mEPSCs recorded from large pyramidal-like neurons, an effect that could be blocked by co-application of a ghrelin receptor antagonist. In ad libitum fed rats, intra-amygdala administration of ghrelin produced a large orexigenic response that lasted throughout the 4 hr of testing. Conversely, in hungry, fasted rats ghrelin receptor blockade in the amygdala significantly reduced food intake. Finally, we investigated a possible interaction between ghrelin's effects on feeding control and emotional reactivity exerted at the level of the amygdala. In rats allowed to feed during a 1-hour period between ghrelin injection and anxiety testing (elevated plus maze and open field, intra-amygdala ghrelin had no effect on anxiety-like behavior. By contrast, if the rats were not given access to food during this 1-hour period, a decrease in anxiety-like behavior was observed in both tests. Collectively, these data indicate that the amygdala is a valid target brain area for ghrelin where its neurobiological effects are important for food intake and for the suppression of emotional (anxiety-like behaviors if food is not available.

  4. Electrophysiological Evaluation of People With Volatile Substance Addiction

    Directory of Open Access Journals (Sweden)

    Nurten Uzun

    2008-02-01

    Full Text Available OBJECTIVE: Scientific BACKGROUND: There is an increase in addiction of volatile substances in recent years. Miscellaneous electrophysiological pathological findings are determined in volatile substance abusers. OBJECTIVE: In this study, we aim to examine the neurologic effects of these substances by electrophysiologic methods. METHODS: Cases and METHOD: Twenty-three patients from Bakirkoy Psychiatry Hospital, Alcohol and Substance Addiction Research and Treatment Center were included in this study. Motor and sensory nerve conduction studies, somatosensorial, visual and auditory evoked potentials (SEP, VEP, BAEP as well as electroencephalography (EEG were studied in all 23 patients. The results were compared with the published data and the values of age matched 19 normal controls. RESULTS: RESULTS: In nerve conduction studies, there were pathological findings in 14 (60.9% cases, in three (13% mild sensorimotor polyneuropathy was determined. Tibial nerve motor distal latencies as well as median nerve sensorial and sural nerve distal latencies were longer in patients compared to controls (p<0.05. SEP findings were pathological in six (26.1% cases, VEP in two (8.7% cases and BAEP in eight (34.8% cases. Scalp SEP distal latency by tibial nerve stimulation as well as distal latencies of right and left V. wave, left III-V interpeak latency, right and left interpeak latencies and I-V interaural latency difference in BAEP were longer in abusers (p<0.05. Although it was not statistically significant, the ratio of pathological findings was higher if the exposure time was over 2 years. EEG was found to be normal in all patients. CONCLUSION: YORUM: Our results showed that toluene results in slowly progressive multifocal central nervous system damage and subclinical damage could be determined in early stages by electrophysiologic methods

  5. The risk of leukaemia in young children from exposure to tritium and carbon-14 in the discharges of German nuclear power stations and in the fallout from atmospheric nuclear weapons testing

    Energy Technology Data Exchange (ETDEWEB)

    Wakeford, Richard [The University of Manchester, Centre for Occupational and Environmental Health, Institute of Population Health, Manchester (United Kingdom)

    2014-05-15

    Towards the end of 2007, the results were published from a case-control study (the ''KiKK Study'') of cancer in young children, diagnosed <5 years of age during 1980-2003 while resident near nuclear power stations in western Germany. The study found a tendency for cases of leukaemia to live closer to the nearest nuclear power station than their matched controls, producing an odds ratio that was raised to a statistically significant extent for residence within 5 km of a nuclear power station. The findings of the study received much publicity, but a detailed radiological risk assessment demonstrated that the radiation doses received by young children from discharges of radioactive material from the nuclear reactors were much lower than those received from natural background radiation and far too small to be responsible for the statistical association reported in the KiKK Study. This has led to speculation that conventional radiological risk assessments have grossly underestimated the risk of leukaemia in young children posed by exposure to man-made radionuclides, and particular attention has been drawn to the possible role of tritium and carbon-14 discharges in this supposedly severe underestimation of risk. Both {sup 3}H and {sup 14}C are generated naturally in the upper atmosphere, and substantial increases in these radionuclides in the environment occurred as a result of their production by atmospheric testing of nuclear weapons during the late 1950s and early 1960s. If the leukaemogenic effect of these radionuclides has been seriously underestimated to the degree necessary to explain the KiKK Study findings, then a pronounced increase in the worldwide incidence of leukaemia among young children should have followed the notably elevated exposure to {sup 3}H and {sup 14}C from nuclear weapons testing fallout. To investigate this hypothesis, the time series of incidence rates of leukaemia among young children <5 years of age at diagnosis has been

  6. Analyzing clinical and electrophysiological characteristics of Paroxysmal Dyskinesia

    Directory of Open Access Journals (Sweden)

    Jue-qian Zhou

    2011-01-01

    Full Text Available The classification, clinical and electrophysiological characteristics, treatment outcome and pathogenesis of paroxysmal dyskinesia were summarized and analyzed. Paroxysmal dyskinesia was classified into three types. Different types had different incentives in clinical practice. Patients were mostly male adolescents, and the attacks, which were in various forms, manifested as dysmyotonia of choreoathetosis, body torsion and facemaking; no disturbance of consciousness during attacks. Electroencephalogram and other examinations showed no specific abnormalities during both the attacks and interictal period. Paroxysmal dyskinesia was an independent disease and different from epilepsy.

  7. Development and evaluation of test stations for the quality assurance of the silicon micro-strip detector modules for the CMS experiment

    International Nuclear Information System (INIS)

    Poettgens, M.

    2007-01-01

    CMS (Compact Muon Solenoid) is one of four large-scale detectors which will be operated at the LHC (Large Hadron Collider) at the European Laboratory for Particle Physics (CERN). For the search for new physics the reconstruction of the collision products and their properties is essential. In the innermost part of the CMS detector the traces of ionizing particles are measured utilizing a silicon tracker. A large fraction of this detector is equipped with silicon micro-strip modules which provide a precise space resolution in 1-dimension. A module consists of a sensor for detection of particles, the corresponding read-out electronics (hybrid) and a mechanical support structure. Since the 15,148 modules, which will be installed in the silicon micro-strip detector, have a total sensitive surface area of about 198 m 2 , the inner tracker of CMS is the largest silicon tracking detector, which has ever been built. While the sensors and hybrids are produced in industry, the construction of the modules and the control of the quality is done by the members of the 21 participating institutes. Since the access to the silicon micro-strip tracker will be very limited after the installation in the CMS detector the installed modules must be of high quality. For this reason the modules are thoroughly tested and the test results are uploaded to a central database. By the development of a read-out system and the corresponding software the III. Physikalisches Institut made an important contribution for the electrical and functional quality control of hybrids and modules. The read-out system provides all features for the operation and test of hybrids and modules and stands out due to high reliability and simple handling. Because a very user-friedly and highly automated software it became the official test tool and was integrated in various test stands. The test stands, in which the read-out system is integrated in, are described and the tests which are implemented in the corresponding

  8. Secure base stations

    NARCIS (Netherlands)

    Bosch, Peter; Brusilovsky, Alec; McLellan, Rae; Mullender, Sape J.; Polakos, Paul

    2009-01-01

    With the introduction of the third generation (3G) Universal Mobile Telecommunications System (UMTS) base station router (BSR) and fourth generation (4G) base stations, such as the 3rd Generation Partnership Project (3GPP) Long Term Evolution (LTE) Evolved Node B (eNB), it has become important to

  9. INTERACT Station Catalogue - 2015

    DEFF Research Database (Denmark)

    INTERACT stations are located in all major environmental envelopes of the Arctic providing an ideal platform for studying climate change and its impact on the environment and local communities. Since alpine environments face similar changes and challenges as the Arctic, the INTERACT network also ...... catalogue includes descriptions of 73 research stations included in the network at the time of printing....

  10. Meyrin Petrol Station

    CERN Multimedia

    2006-01-01

    Please note that the Meyrin petrol station will be closed for maintenance work on Tuesday 19 and Wednesday 20 December 2006. If you require petrol during this period we invite you to use the Prévessin petrol station, which will remain open. TS-IC-LO Section Tel.: 77039 - 73793

  11. Nuclear power stations licensing

    International Nuclear Information System (INIS)

    Solito, J.

    1978-04-01

    The judicial aspects of nuclear stations licensing are presented. The licensing systems of the United States, Spain, France and Federal Republic of Germany are focused. The decree n 0 60.824 from July 7 sup(th), 1967 and the following legislation which define the systematic and area of competence in nuclear stations licensing are analysed [pt

  12. SPS rectifier stations

    CERN Multimedia

    CERN PhotoLab

    1974-01-01

    The first of the twelves SPS rectifier stations for the bending magnets arrived at CERN at the end of the year. The photograph shows a station with the rectifiers on the left and in the other three cubicles the chokes, capacitors and resistor of the passive filter.

  13. Ondergronds Station Blijdorp, Rotterdam

    NARCIS (Netherlands)

    Hijma, M.P.|info:eu-repo/dai/nl/266562426; Cohen, K.M.|info:eu-repo/dai/nl/185633374

    2014-01-01

    Het is in de herfst van 2005. Een lief meisje, Marieke, rijdt op haar vouwfiets door Rotterdam. Bij het Centraal Station is het al tijden een grote bouwplaats. Onder de nieuwe hal komt een veel groter metrostation en ook onder de Statenweg in Blijdorp is een grote bouwput voor een nieuw station.

  14. [STEM on Station Education

    Science.gov (United States)

    Lundebjerg, Kristen

    2016-01-01

    The STEM on Station team is part of Education which is part of the External Relations organization (ERO). ERO has traditional goals based around BHAG (Big Hairy Audacious Goal). The BHAG model is simplified to a saying: Everything we do stimulates actions by others to advance human space exploration. The STEM on Station education initiate is a project focused on bringing off the earth research and learning into classrooms. Educational resources such as lesson plans, activities to connect with the space station and STEM related contests are available and hosted by the STEM on Station team along with their partners such as Texas Instruments. These educational activities engage teachers and students in the current happenings aboard the international space station, inspiring the next generation of space explorers.

  15. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    . The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high...... overloading, more reference points might be necessary to represent various transformer loading levels. The subject of safety in Central Station is also addressed. A number of safety rules based on European standards apply to AC charging equipment up to 44 kW. The connection interlock and the automatic de......-energization are identified as fundamental requirements for safety in such a charging station. The connection interlock is a solution which ensures that no power is applied to the DC cable when the EV connector is not connected. The automatic de-energization device ensures that whenever a strain on the cable is detected, e...

  16. A space-fractional Monodomain model for cardiac electrophysiology combining anisotropy and heterogeneity on realistic geometries

    Science.gov (United States)

    Cusimano, N.; Gerardo-Giorda, L.

    2018-06-01

    Classical models of electrophysiology do not typically account for the effects of high structural heterogeneity in the spatio-temporal description of excitation waves propagation. We consider a modification of the Monodomain model obtained by replacing the diffusive term of the classical formulation with a fractional power of the operator, defined in the spectral sense. The resulting nonlocal model describes different levels of tissue heterogeneity as the fractional exponent is varied. The numerical method for the solution of the fractional Monodomain relies on an integral representation of the nonlocal operator combined with a finite element discretisation in space, allowing to handle in a natural way bounded domains in more than one spatial dimension. Numerical tests in two spatial dimensions illustrate the features of the model. Activation times, action potential duration and its dispersion throughout the domain are studied as a function of the fractional parameter: the expected peculiar behaviour driven by tissue heterogeneities is recovered.

  17. Hybrid automata models of cardiac ventricular electrophysiology for real-time computational applications.

    Science.gov (United States)

    Andalam, Sidharta; Ramanna, Harshavardhan; Malik, Avinash; Roop, Parthasarathi; Patel, Nitish; Trew, Mark L

    2016-08-01

    Virtual heart models have been proposed for closed loop validation of safety-critical embedded medical devices, such as pacemakers. These models must react in real-time to off-the-shelf medical devices. Real-time performance can be obtained by implementing models in computer hardware, and methods of compiling classes of Hybrid Automata (HA) onto FPGA have been developed. Models of ventricular cardiac cell electrophysiology have been described using HA which capture the complex nonlinear behavior of biological systems. However, many models that have been used for closed-loop validation of pacemakers are highly abstract and do not capture important characteristics of the dynamic rate response. We developed a new HA model of cardiac cells which captures dynamic behavior and we implemented the model in hardware. This potentially enables modeling the heart with over 1 million dynamic cells, making the approach ideal for closed loop testing of medical devices.

  18. FieldTrip: Open source software for advanced analysis of MEG, EEG, and invasive electrophysiological data.

    Science.gov (United States)

    Oostenveld, Robert; Fries, Pascal; Maris, Eric; Schoffelen, Jan-Mathijs

    2011-01-01

    This paper describes FieldTrip, an open source software package that we developed for the analysis of MEG, EEG, and other electrophysiological data. The software is implemented as a MATLAB toolbox and includes a complete set of consistent and user-friendly high-level functions that allow experimental neuroscientists to analyze experimental data. It includes algorithms for simple and advanced analysis, such as time-frequency analysis using multitapers, source reconstruction using dipoles, distributed sources and beamformers, connectivity analysis, and nonparametric statistical permutation tests at the channel and source level. The implementation as toolbox allows the user to perform elaborate and structured analyses of large data sets using the MATLAB command line and batch scripting. Furthermore, users and developers can easily extend the functionality and implement new algorithms. The modular design facilitates the reuse in other software packages.

  19. White Mountain Research Station: 25 years of high-altitude research. [organization and functions of test facility for high altitude research

    Science.gov (United States)

    Pace, N.

    1973-01-01

    The organization and functions of a test facility for conducting research projects at high altitudes are discussed. The projects conducted at the facility include the following: (1) bird physiology, (2) cardiorespiratory physiology, (3) endocrinological studies, (4) neurological studies, (5) metabolic studies, and (6) geological studies.

  20. Surry Power Station, Units 1 and 2. Annual operating report for 1976, section 2: core performance and startup physics test reports

    International Nuclear Information System (INIS)

    1977-01-01

    The analyses of four core performance indicators including burnup distribution, reactivity depletion, power distribution, and primary coolant activity are discussed. Information is presented concerning fuel densification monitoring; start-up physics testing; and James River temperature, salinity, fish, biota, and plankton entrainment monitoring

  1. Development of a test station for the illustration of a hydraulic heating network; Entwicklung eines Pruefstandes zur Abbildung eines hydraulischen Heizungsnetzwerks

    Energy Technology Data Exchange (ETDEWEB)

    Kopmann, Nina; Adolph, Michael; Mueller, Dirk [RWTH Aachen Univ. E.ON Energy Research Center (Germany). Inst. for Energy Efficient Buildings and Indoor Climate

    2011-07-01

    As the parameters describing air currents in rooms will change to the opposite when the characteristic length is shortened, small-scale investigations of room air currents are not possible. For this reason, the E.ON Energy Research Center set up a ''Hardware-in-the-Loop'' (HiL) test stand which models a real hydraulic heating system of an apartment or a building. The test stand consists of several interconnected model rooms with typical heating units, and only the enclosing building volume is reduced. The model rooms all have a volume of 3-4 m{sup 3}. Depending on the heat emitted by the radiators, the boundary conditions of air supply (volume flow and temperature) and of the walls (wall surface tempeartures) are calculated using the simulation software Modelica and are emulated in the test stand. The measured heat emissions of the radiators are used as boundary conditions in the thermohydraulic simulations. The function of the HiL test stand was first tested in a single model room. Verification of the test stand concept took place via measurements of the velocity and temperature field in front of the radiator, which were compared with measurements in a thermal test stand with realistic room dimensions. [German] Da die Parameter zur Beschreibung von Raumluftstroemungen bei einer Verkleinerung der charakteristischen Laenge ein gegensaetzliches Verhalten aufweisen, koennen die Untersuchungen von Raumluftstroemungen nicht kleinskaliert werden. Deswegen wird am E.ON Energy Research Center ein ''Hardware-in-the-Loop'' (HiL) -Pruefstand entwickelt, welcher ein reales hydraulisches Heizungsnetz einer Wohnung oder eines Gebaeudes mit geringem Platzbedarf nachbildet. In den Pruefstand, welcher aus mehreren vernetzten Modellraeumen besteht, werden typische Heizkoerper eingebaut und nur das umschliessende Volumen wird verkleinert. Die Modellraeume haben jeweils ein Volumen von 3-4 m{sup 3}. Abhaengig von der Waermeabgabe der Heizkoerper

  2. Audiological and electrophysiological alterations in HIV-infected individuals subjected or not to antiretroviral therapy.

    Science.gov (United States)

    Matas, Carla Gentile; Samelli, Alessandra Giannella; Magliaro, Fernanda Cristina Leite; Segurado, Aluisio

    2017-08-02

    The Human Immunodeficiency Virus (HIV) and infections related to it can affect multiple sites in the hearing system. The use of High-Activity Anti-Retroviral Therapy (HAART) can cause side effects such as ototoxicity. Thus, no consistent patterns of hearing impairment in adults with Human Immunodeficiency Virus / Acquired Immune Deficiency Syndrome have been established, and the problems that affect the hearing system of this population warrant further research. This study aimed to compare the audiological and electrophysiological data of Human Immunodeficiency Virus-positive patients with and without Acquired Immune Deficiency Syndrome, who were receiving High-Activity Anti-Retroviral Therapy, to healthy individuals. It was a cross-sectional study conducted with 71 subjects (30-48 years old), divided into groups: Research Group I: 16 Human Immunodeficiency Virus-positive individuals without Acquired Immunodeficiency Syndrome (not receiving antiretroviral treatment); Research Group II: 25 Human Immunodeficiency Virus-positive individuals with Acquired Immunodeficiency Syndrome (receiving antiretroviral treatment); Control Group: 30 healthy subjects. All individuals were tested by pure-tone air conduction thresholds at 0.25-8kHz, extended high frequencies at 9-20kHz, electrophysiological tests (Auditory Brainstem Response - ABR, Middle Latency Responses - MLR, Cognitive Potential - P300). Research Group I and Research Group II had higher hearing thresholds in both conventional and high frequency audiometry when compared to the control group, prolonged latency of waves I, III, V and interpeak I-V in Auditory Brainstem Response and prolonged latency of P300 Cognitive Potential. Regarding Middle Latency Responses, there was a decrease in the amplitude of the Pa wave of Research Group II compared to the Research Group I. Both groups with Human Immunodeficiency Virus had higher hearing thresholds when compared to healthy individuals (group exposed to antiretroviral

  3. Development and evaluation of test stations for the quality assurance of the silicon micro-strip detector modules for the CMS experiment

    Energy Technology Data Exchange (ETDEWEB)

    Poettgens, M.

    2007-11-22

    CMS (Compact Muon Solenoid) is one of four large-scale detectors which will be operated at the LHC (Large Hadron Collider) at the European Laboratory for Particle Physics (CERN). For the search for new physics the reconstruction of the collision products and their properties is essential. In the innermost part of the CMS detector the traces of ionizing particles are measured utilizing a silicon tracker. A large fraction of this detector is equipped with silicon micro-strip modules which provide a precise space resolution in 1-dimension. A module consists of a sensor for detection of particles, the corresponding read-out electronics (hybrid) and a mechanical support structure. Since the 15,148 modules, which will be installed in the silicon micro-strip detector, have a total sensitive surface area of about 198 m{sup 2}, the inner tracker of CMS is the largest silicon tracking detector, which has ever been built. While the sensors and hybrids are produced in industry, the construction of the modules and the control of the quality is done by the members of the 21 participating institutes. Since the access to the silicon micro-strip tracker will be very limited after the installation in the CMS detector the installed modules must be of high quality. For this reason the modules are thoroughly tested and the test results are uploaded to a central database. By the development of a read-out system and the corresponding software the III. Physikalisches Institut made an important contribution for the electrical and functional quality control of hybrids and modules. The read-out system provides all features for the operation and test of hybrids and modules and stands out due to high reliability and simple handling. Because a very user-friedly and highly automated software it became the official test tool and was integrated in various test stands. The test stands, in which the read-out system is integrated in, are described and the tests which are implemented in the

  4. Conduction disturbances after TAVR: Electrophysiological studies and pacemaker dependency.

    Science.gov (United States)

    Makki, Nader; Dollery, Jenn; Jones, Danielle; Crestanello, Juan; Lilly, Scott

    Permanent pacemaker (PPM) placement occurs in 5-20% of patients after transcatheter aortic valve replacement (TAVR). Although predictors of pacemaker implantation have been established, features that predispose patients to pacemaker utilization on follow up have not been widely reported. We performed a retrospective review of patients undergoing commercial TAVR between 2011 and 2016. We collated patients that underwent in-hospital PPM implantation and had a follow up of at least 3months. Data abstraction was performed for electrophysiological studies (EPS), pacemaker indication, timing, and device interrogation for pacemaker dependency on follow up. A total of 24 patients received in-hospital PPM post-TAVR (14% of total cohort), and mean follow up was 22months. Indications for PPM included resting complete heart block (CHB; 15/24, 63%), left bundle branch block and abnormal electrophysiological study (EPS; 7/24, 29%), alternating bundle branch block (1/24, 4%) and tachy-brady syndrome (1/24, 4%). Pacemaker dependency (underlying ventricular asystole, complete heart block, or >50% pacing) occurred in 8/24 patients (33%) during follow-up, 7 of whom had resting CHB, and one with CHB invoked during EPS. Pacemaker dependency after TAVR is common among those that exhibited CHB, but not among those with a prolonged HV delay during EPS. Although preliminary, these observations are relevant to management of rhythm disturbances after TAVR, and may inform the practice of EPS-based PPM implantation. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Electrophysiological Correlates of Reading the Single- and Interactive-Mind

    Science.gov (United States)

    Wang, Yi-Wen; Zheng, Yu-Wei; Lin, Chong-De; Wu, Jie; Shen, De-Li

    2011-01-01

    Understanding minds is the cognitive basis of successful social interaction. In everyday life, human mental activity often happens at the moment of social interaction among two or multiple persons instead of only one-person. Understanding the interactive mind of two- or multi-person is more complex and higher than understanding the single-person mind in the hierarchical structure of theory of mind. Understanding the interactive mind maybe differentiate from understanding the single mind. In order to examine the dissociative electrophysiological correlates of reading the single mind and reading the interactive mind, the 64 channels event-related potentials were recorded while 16 normal adults were observing three kinds of Chinese idioms depicted physical scenes, one-person with mental activity, and two- or multi-person with mental interaction. After the equivalent N400, in the 500- to 700-ms epoch, the mean amplitudes of late positive component (LPC) over frontal for reading the single mind and reading the interactive mind were significantly more positive than for physical representation, while there was no difference between the former two. In the 700- to 800-ms epoch, the mean amplitudes of LPC over frontal–central for reading the interactive mind were more positive than for reading the single mind and physical representation, while there was no difference between the latter two. The present study provides electrophysiological signature of the dissociations between reading the single mind and reading the interactive mind. PMID:21845178

  6. Electrophysiological correlates of reading the single- and interactive-mind

    Directory of Open Access Journals (Sweden)

    Yi-Wen eWang

    2011-07-01

    Full Text Available Understanding minds is the cognitive basis of successful social interaction. In everyday life, human mental activity often happens at the moment of social interaction among two or multiple persons instead of only one person. Understanding the interactive mind of two- or multi-person is more complex and higher than understanding the single-person mind in the hierarchical structure of theory-of-mind. Understanding the interactive mind maybe differentiate from understanding the single mind. In order to examine the dissociative electrophysiological correlates of reading the single mind and reading the interactive mind, the 64 channels event-related potentials (ERP were recorded while 16 normal adults were observing three kinds of Chinese idioms depicted physical scenes, one-person with mental activity and two- or multi-person with mental interaction. After the equivalent N400, in the 500- to 700-ms epoch, the mean amplitudes of late positive component (LPC over frontal for reading the single mind and reading the interactive mind were significantly more positive than for physical representation, while there was no difference between the former two. In the 700-to 800-ms epoch, the mean amplitudes of LPC over frontal-central for reading the interactive mind were more positive than for reading the single mind and physical representation, while there was no difference between the latter two. The present study provides electrophysiological signature of the dissociations between reading the single mind and reading the interactive mind.

  7. Behavioral and electrophysiological signatures of word translation processes.

    Science.gov (United States)

    Jost, Lea B; Radman, Narges; Buetler, Karin A; Annoni, Jean-Marie

    2018-01-31

    Translation is a demanding process during which a message is analyzed, translated and communicated from one language to another. Despite numerous studies on translation mechanisms, the electrophysiological processes underlying translation with overt production remain largely unexplored. Here, we investigated how behavioral response patterns and spatial-temporal brain dynamics differ in a translation compared to a control within-language word-generation task. We also investigated how forward and backward translation differs on the behavioral and electrophysiological level. To address these questions, healthy late bilingual subjects performed a translation and a within-language control task while a 128-channel EEG was recorded. Behavioral data showed faster responses for translation compared to within-language word generation and faster responses for backward than forward translation. The ERP-analysis revealed stronger early ( processes for between than within word generation. Later (424-630ms) differences were characterized by distinct engagement of domain-general control networks, namely self-monitoring and lexical access interference. Language asymmetry effects occurred at a later stage (600ms), reflecting differences in conceptual processing characterized by a larger involvement of areas implicated in attention, arousal and awareness for forward versus backward translation. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Obesity, Cardiovascular Fitness, and Inhibition Function: An Electrophysiological Study

    Directory of Open Access Journals (Sweden)

    Tai-Fen Song

    2016-07-01

    Full Text Available The purpose of the present study was to examine how obesity and cardiovascular fitness are associated with the inhibition aspect of executive function from behavioral and electrophysiological perspectives. One hundred college students, aged 18 to 25 years, were categorized into four groups of equal size on the basis of body mass index and cardiovascular fitness: a normal-weight and high-fitness (NH group, an obese-weight and high-fitness (OH group, a normal-weight and low-fitness (NL group, and an obese-weight and low-fitness (OL group. Behavioral measures of response time and number of errors, as well as event-related potential (ERP measures of P3 and N1, were assessed during the Stroop Task. The results revealed that, in general, the NH group exhibited shorter response times and larger P3 amplitudes relative to the OH, NL, and OL groups, wherein the OL group exhibited the longest response time in the incongruent condition. No group differences in N1 indices were also revealed. These findings suggest that the status of being both normal weight and having high cardiovascular fitness is associated with better behavioral and later stages of electrophysiological indices of inhibition. However, these benefits in inhibition function would be lost in an individual who is obese or has low cardiovascular fitness, reflecting the importance keeping both normal weight and having high cardiovascular fitness.

  9. Somatomotor and oculomotor inferior olivary neurons have distinct electrophysiological phenotypes

    Science.gov (United States)

    Urbano, Francisco J.; Simpson, John I.; Llinás, Rodolfo R.

    2006-01-01

    The electrophysiological properties of rat inferior olive (IO) neurons in the dorsal cap of Kooy (DCK) and the adjacent ventrolateral outgrowth (VLO) were compared with those of IO neurons in the principal olive (PO). Whereas DCK/VLO neurons are involved in eye movement control via their climbing fiber projection to the cerebellar flocculus, PO neurons control limb and digit movements via their climbing fiber projection to the lateral cerebellar hemisphere. In vitro patch recordings from DCK/VLO neurons revealed that low threshold calcium currents, Ih currents, and subthreshold oscillations are lacking in this subset of IO neurons. The recordings of activity in DCK neurons obtained by using voltage-sensitive dye imaging showed that activity is not limited to a single neuron, but rather that clusters of DCK neurons can be active in unison. These electrophysiological results show that the DCK/VLO neurons have unique properties that set them apart from the neurons in the PO nucleus. This finding indicates that motor control, from the perspective of the olivocerebellar system, is fundamentally different for the oculomotor and the somatomotor systems. PMID:17050678

  10. Simulation Methods and Validation Criteria for Modeling Cardiac Ventricular Electrophysiology.

    Directory of Open Access Journals (Sweden)

    Shankarjee Krishnamoorthi

    Full Text Available We describe a sequence of methods to produce a partial differential equation model of the electrical activation of the ventricles. In our framework, we incorporate the anatomy and cardiac microstructure obtained from magnetic resonance imaging and diffusion tensor imaging of a New Zealand White rabbit, the Purkinje structure and the Purkinje-muscle junctions, and an electrophysiologically accurate model of the ventricular myocytes and tissue, which includes transmural and apex-to-base gradients of action potential characteristics. We solve the electrophysiology governing equations using the finite element method and compute both a 6-lead precordial electrocardiogram (ECG and the activation wavefronts over time. We are particularly concerned with the validation of the various methods used in our model and, in this regard, propose a series of validation criteria that we consider essential. These include producing a physiologically accurate ECG, a correct ventricular activation sequence, and the inducibility of ventricular fibrillation. Among other components, we conclude that a Purkinje geometry with a high density of Purkinje muscle junctions covering the right and left ventricular endocardial surfaces as well as transmural and apex-to-base gradients in action potential characteristics are necessary to produce ECGs and time activation plots that agree with physiological observations.

  11. Simulation Methods and Validation Criteria for Modeling Cardiac Ventricular Electrophysiology.

    Science.gov (United States)

    Krishnamoorthi, Shankarjee; Perotti, Luigi E; Borgstrom, Nils P; Ajijola, Olujimi A; Frid, Anna; Ponnaluri, Aditya V; Weiss, James N; Qu, Zhilin; Klug, William S; Ennis, Daniel B; Garfinkel, Alan

    2014-01-01

    We describe a sequence of methods to produce a partial differential equation model of the electrical activation of the ventricles. In our framework, we incorporate the anatomy and cardiac microstructure obtained from magnetic resonance imaging and diffusion tensor imaging of a New Zealand White rabbit, the Purkinje structure and the Purkinje-muscle junctions, and an electrophysiologically accurate model of the ventricular myocytes and tissue, which includes transmural and apex-to-base gradients of action potential characteristics. We solve the electrophysiology governing equations using the finite element method and compute both a 6-lead precordial electrocardiogram (ECG) and the activation wavefronts over time. We are particularly concerned with the validation of the various methods used in our model and, in this regard, propose a series of validation criteria that we consider essential. These include producing a physiologically accurate ECG, a correct ventricular activation sequence, and the inducibility of ventricular fibrillation. Among other components, we conclude that a Purkinje geometry with a high density of Purkinje muscle junctions covering the right and left ventricular endocardial surfaces as well as transmural and apex-to-base gradients in action potential characteristics are necessary to produce ECGs and time activation plots that agree with physiological observations.

  12. Electrophysiologic Assessments of Involuntary Movements: Tremor and Myoclonus

    Directory of Open Access Journals (Sweden)

    Hyun-Dong Park

    2009-05-01

    Full Text Available Tremor is defined as a rhythmical, involuntary oscillatory movement of a body part. Although neurological examination reveals information regarding its frequency, regularity, amplitude, and activation conditions, the electrophysiological investigations help in confirming the tremor, in differentiating it from other hyperkinetic disorders like myoclonus, and may provide etiological clues. Accelerometer with surface electromyogram (EMG can be used to document the dominant frequency of a tremor, which may be useful as certain frequencies are more characteristic of specific etiologies than others hyperkinetic disorders. It may show rhythmic bursts, duration and activation pattern (alternating or synchronous. Myoclonus is a quick, involuntary movement. Electrophysiological studies may helpful in the evaluation of myoclonus, not only for confirming the clinical diagnosis but also for understanding the underlying physiological mechanisms. Electroencephalogram (EEG-EMG correlates can give us important information about myoclonus. Jerk-locked back-averaging and evoked potentials with recording of the long-latency, long-loop reflexes are currently available to study the pathophysiology of myoclonus.

  13. Electrophysiological mechanisms of the SI SII SIII electrocardiographic morphology

    International Nuclear Information System (INIS)

    Bayes de Luna, A.; Carrio, I.; Subirana, M.T.; Torner, P.; Cosin, J.; Sagues, F.; Guindo, J.

    1987-01-01

    We studied three groups of individuals by means of spatial-velocity electrocardiograms and thallium-201 myocardial imaging to figure out the electrophysiological explanation of the SI SII SIII electrocardiographic morphology. We studied twelve healthy individuals without SI SII SIII, seven healthy individuals with SI SII SIII and fifteen patients with chronic obstructive pulmonary disease with SI SII SIII. The average values of the QRS-E and QRS-F intervals were higher in the second and third groups than in the first. One patient of the second group and thirteen of the third showed right ventricular enlargement. The slowing down of the right ventricular conduction explained the SI SII SIII morphology in normal individuals in more than half the cases. In patients with chronic obstructive pulmonary disease with SI SII SIII the conduction delay plays an important part in the electrogenesis of the right ventricular enlargement electrocardiographic morphology. We think that these observations can give further data about the electrophysiologic mechanism of the SI SII SIII morphology

  14. Electrophysiological correlates of mental navigation in blind and sighted people.

    Science.gov (United States)

    Kober, Silvia Erika; Wood, Guilherme; Kampl, Christiane; Neuper, Christa; Ischebeck, Anja

    2014-10-15

    The aim of the present study was to investigate functional reorganization of the occipital cortex for a mental navigation task in blind people. Eight completely blind adults and eight sighted matched controls performed a mental navigation task, in which they mentally imagined to walk along familiar routes of their hometown during a multi-channel EEG measurement. A motor imagery task was used as control condition. Furthermore, electrophysiological activation patterns during a resting measurement with open and closed eyes were compared between blind and sighted participants. During the resting measurement with open eyes, no differences in EEG power were observed between groups, whereas sighted participants showed higher alpha (8-12Hz) activity at occipital sites compared to blind participants during an eyes-closed resting condition. During the mental navigation task, blind participants showed a stronger event-related desynchronization in the alpha band over the visual cortex compared to sighted controls indicating a stronger activation in this brain region in the blind. Furthermore, groups showed differences in functional brain connectivity between fronto-central and parietal-occipital brain networks during mental navigation indicating stronger visuo-spatial processing in sighted than in blind people during mental navigation. Differences in electrophysiological parameters between groups were specific for mental navigation since no group differences were observed during motor imagery. These results indicate that in the absence of vision the visual cortex takes over other functions such as spatial navigation. Copyright © 2014 Elsevier B.V. All rights reserved.

  15. Electrophysiological biomarkers of epileptogenicity after traumatic brain injury.

    Science.gov (United States)

    Perucca, Piero; Smith, Gregory; Santana-Gomez, Cesar; Bragin, Anatol; Staba, Richard

    2018-06-05

    Post-traumatic epilepsy is the architype of acquired epilepsies, wherein a brain insult initiates an epileptogenic process culminating in an unprovoked seizure after weeks, months or years. Identifying biomarkers of such process is a prerequisite for developing and implementing targeted therapies aimed at preventing the development of epilepsy. Currently, there are no validated electrophysiological biomarkers of post-traumatic epileptogenesis. Experimental EEG studies using the lateral fluid percussion injury model have identified three candidate biomarkers of post-traumatic epileptogenesis: pathological high-frequency oscillations (HFOs, 80-300 Hz); repetitive HFOs and spikes (rHFOSs); and reduction in sleep spindle duration and dominant frequency at the transition from stage III to rapid eye movement sleep. EEG studies in humans have yielded conflicting data; recent evidence suggests that epileptiform abnormalities detected acutely after traumatic brain injury carry a significantly increased risk of subsequent epilepsy. Well-designed studies are required to validate these promising findings, and ultimately establish whether there are post-traumatic electrophysiological features which can guide the development of 'antiepileptogenic' therapies. Copyright © 2017. Published by Elsevier Inc.

  16. Automatic fitting of spiking neuron models to electrophysiological recordings

    Directory of Open Access Journals (Sweden)

    Cyrille Rossant

    2010-03-01

    Full Text Available Spiking models can accurately predict the spike trains produced by cortical neurons in response to somatically injected currents. Since the specific characteristics of the model depend on the neuron, a computational method is required to fit models to electrophysiological recordings. The fitting procedure can be very time consuming both in terms of computer simulations and in terms of code writing. We present algorithms to fit spiking models to electrophysiological data (time-varying input and spike trains that can run in parallel on graphics processing units (GPUs. The model fitting library is interfaced with Brian, a neural network simulator in Python. If a GPU is present it uses just-in-time compilation to translate model equations into optimized code. Arbitrary models can then be defined at script level and run on the graphics card. This tool can be used to obtain empirically validated spiking models of neurons in various systems. We demonstrate its use on public data from the INCF Quantitative Single-Neuron Modeling 2009 competition by comparing the performance of a number of neuron spiking models.

  17. No effects of power line frequency extremely low frequency electromagnetic field exposure on selected neurobehavior tests of workers inspecting transformers and distribution line stations versus controls.

    Science.gov (United States)

    Li, Li; Xiong, De-fu; Liu, Jia-wen; Li, Zi-xin; Zeng, Guang-cheng; Li, Hua-liang

    2014-03-01

    We aimed to evaluate the interference of 50 Hz extremely low frequency electromagnetic field (ELF-EMF) occupational exposure on the neurobehavior tests of workers performing tour-inspection close to transformers and distribution power lines. Occupational short-term "spot" measurements were carried out. 310 inspection workers and 300 logistics staff were selected as exposure and control. The neurobehavior tests were performed through computer-based neurobehavior evaluation system, including mental arithmetic, curve coincide, simple visual reaction time, visual retention, auditory digit span and pursuit aiming. In 500 kV areas electric field intensity at 71.98% of total measured 590 spots were above 5 kV/m (national occupational standard), while in 220 kV areas electric field intensity at 15.69% of total 701 spots were above 5 kV/m. Magnetic field flux density at all the spots was below 1,000 μT (ICNIRP occupational standard). The neurobehavior score changes showed no statistical significance. Results of neurobehavior tests among different age, seniority groups showed no significant changes. Neurobehavior changes caused by daily repeated ELF-EMF exposure were not observed in the current study.

  18. Prism Adaptation Alters Electrophysiological Markers of Attentional Processes in the Healthy Brain.

    Science.gov (United States)

    Martín-Arévalo, Elisa; Laube, Inga; Koun, Eric; Farnè, Alessandro; Reilly, Karen T; Pisella, Laure

    2016-01-20

    Neglect patients typically show a rightward attentional orienting bias and a strong disengagement deficit, such that they are especially slow in responding to left-sided targets after right-sided cues (Posner et al., 1984). Prism adaptation (PA) can reduce diverse debilitating neglect symptoms and it has been hypothesized that PA's effects are so generalized that they might be mediated by attentional mechanisms (Pisella et al., 2006; Redding and Wallace, 2006). In neglect patients, performance on spatial attention tasks improves after rightward-deviating PA (Jacquin-Courtois et al., 2013). In contrast, in healthy subjects, although there is evidence that leftward-deviating PA induces neglect-like performance on some visuospatial tasks, behavioral studies of spatial attention tasks have mostly yielded negative results (Morris et al., 2004; Bultitude et al., 2013). We hypothesized that these negative behavioral findings might reflect the limitations of behavioral measures in healthy subjects. Here we exploited the sensitivity of event-related potentials to test the hypothesis that electrophysiological markers of attentional processes in the healthy human brain are affected by PA. Leftward-deviating PA generated asymmetries in attentional orienting (reflected in the cue-locked N1) and in attentional disengagement for invalidly cued left targets (reflected in the target-locked P1). This is the first electrophysiological demonstration that leftward-deviating PA in healthy subjects mimics attentional patterns typically seen in neglect patients. Significance statement: Prism adaptation (PA) is a promising tool for ameliorating many deficits in neglect patients and inducing neglect-like behavior in healthy subjects. The mechanisms underlying PA's effects are poorly understood but one hypothesis suggests that it acts by modulating attention. To date, however, there has been no successful demonstration of attentional modulation in healthy subjects. We provide the first

  19. Electrophysiological Data and the Biophysical Modelling of Local Cortical Circuits

    Directory of Open Access Journals (Sweden)

    Dimitris Pinotsis

    2014-03-01

    empirical MEG data and looked for potential determinants of the spectral properties of an individual's gamma response, and how they relate to underlying visual cortex microcircuitry and excitation/inhibition balance. We found correlations between peak gamma frequency and cortical inhibition (parameterized by the excitatory drive to inhibitory cell populations over subjects. This constitutes a compelling illustration of how non-invasive data can provide quantitative estimates of the spatial properties of neural sources and explain systematic variations in the dynamics those sources generate. Furthermore, the conclusions fitted comfortably with studies of contextual interactions and orientation discrimination suggesting that local contextual interactions in V1 are weaker in individuals with a large V1 area [13, 14]. Finally, we will use dynamic causal modeling and neural fields to test specific hypotheses about precision and gain control based on predictive coding formulations of neuronal processing. We exploited finely sampled electrophysiological responses from awake-behaving monkeys and an experimental manipulation (the contrast of visual stimuli to look at changes in the gain and balance of excitatory and inhibitory influences. Our results suggest that increasing contrast effectively increases the sensitivity or gain of superficial pyramidal cells to inputs from spiny stellate populations. Furthermore, they are consistent with intriguing results showing that the receptive fields of V1 units shrinks with increasing visual contrast. The approach we will illustrate in this paper rests on neural field models that are optimized in relation to observed gamma responses from the visual cortex and are – crucially – compared in terms of their evidence. This provides a principled way to address questions about cortical structure, function and the architectures that underlie neuronal computations.

  20. Analyses and estimates of hydraulic conductivity from slug tests in alluvial aquifer underlying Air Force Plant 4 and Naval Air Station-Joint Reserve Base Carswell Field, Fort Worth, Texas

    Science.gov (United States)

    Houston, Natalie A.; Braun, Christopher L.

    2004-01-01

    This report describes the collection, analyses, and distribution of hydraulic-conductivity data obtained from slug tests completed in the alluvial aquifer underlying Air Force Plant 4 and Naval Air Station-Joint Reserve Base Carswell Field, Fort Worth, Texas, during October 2002 and August 2003 and summarizes previously available hydraulic-conductivity data. The U.S. Geological Survey, in cooperation with the U.S. Air Force, completed 30 slug tests in October 2002 and August 2003 to obtain estimates of horizontal hydraulic conductivity to use as initial values in a ground-water-flow model for the site. The tests were done by placing a polyvinyl-chloride slug of known volume beneath the water level in selected wells, removing the slug, and measuring the resulting water-level recovery over time. The water levels were measured with a pressure transducer and recorded with a data logger. Hydraulic-conductivity values were estimated from an analytical relation between the instantaneous displacement of water in a well bore and the resulting rate of head change. Although nearly two-thirds of the tested wells recovered 90 percent of their slug-induced head change in less than 2 minutes, 90-percent recovery times ranged from 3 seconds to 35 minutes. The estimates of hydraulic conductivity range from 0.2 to 200 feet per day. Eighty-three percent of the estimates are between 1 and 100 feet per day.

  1. Space station operations management

    Science.gov (United States)

    Cannon, Kathleen V.

    1989-01-01

    Space Station Freedom operations management concepts must be responsive to the unique challenges presented by the permanently manned international laboratory. Space Station Freedom will be assembled over a three year period where the operational environment will change as significant capability plateaus are reached. First Element Launch, Man-Tended Capability, and Permanent Manned Capability, represent milestones in operational capability that is increasing toward mature operations capability. Operations management concepts are being developed to accomodate the varying operational capabilities during assembly, as well as the mature operational environment. This paper describes operations management concepts designed to accomodate the uniqueness of Space Station Freedoom, utilizing tools and processes that seek to control operations costs.

  2. Waste Transfer Stations

    DEFF Research Database (Denmark)

    Christensen, Thomas Højlund

    2011-01-01

    tion and transport is usually the most costly part of any waste management system; and when waste is transported over a considerable distance or for a long time, transferring the waste from the collection vehicles to more efficient transportation may be economically beneficial. This involves...... a transfer station where the transfer takes place. These stations may also be accessible by private people, offering flexibility to the waste system, including facilities for bulky waste, household hazardous waste and recyclables. Waste transfer may also take place on the collection route from small...... describes the main features of waste transfer stations, including some considerations about the economical aspects on when transfer is advisable....

  3. Conductive Hearing Loss during Infancy: Effects on Later Auditory Brain Stem Electrophysiology.

    Science.gov (United States)

    Gunnarson, Adele D.; Finitzo, Terese

    1991-01-01

    Long-term effects on auditory electrophysiology from early fluctuating hearing loss were studied in 27 children, aged 5 to 7 years, who had been evaluated originally in infancy. Findings suggested that early fluctuating hearing loss disrupts later auditory brain stem electrophysiology. (Author/DB)

  4. Individual Differences in Behavioral and Electrophysiological Measures of Binaural Processing Across the Adult Life Span.

    Science.gov (United States)

    Roup, Christina M; Leigh, Elizabeth D

    2015-06-01

    The purpose of the present study was to examine individual differences in binaural processing across the adult life span. Sixty listeners (aged 23-80 years) with symmetrical hearing were tested. Binaural behavioral processing was measured by the Words-in-Noise Test, the 500-Hz masking level difference, and the Dichotic Digit Test. Electrophysiologic responses were assessed by the auditory middle latency response binaural interaction component. No correlations among binaural measures were found. Age accounted for the greatest amount of variability in speech-in-noise performance. Age was significantly correlated with the Words-in-Noise Test binaural advantage and dichotic ear advantage. Partial correlations, however, revealed that this was an effect of hearing status rather than age per se. Inspection of individual results revealed that 20% of listeners demonstrated reduced binaural performance for at least 2 of the binaural measures. The lack of significant correlations among variables suggests that each is an important measurement of binaural abilities. For some listeners, binaural processing was abnormal, reflecting a binaural processing deficit not identified by monaural audiologic tests. The inclusion of a binaural test battery in the audiologic evaluation is supported given that these listeners may benefit from alternative forms of audiologic rehabilitation.

  5. Testing flight software on the ground: Introducing the hardware-in-the-loop simulation method to the Alpha Magnetic Spectrometer on the International Space Station

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Wenhao, E-mail: wenhao_sun@126.com [Southeast University, Nanjing 210096 (China); Cai, Xudong [Massachusetts Institute of Technology, MA 02139-4307 (United States); Meng, Qiao [Southeast University, Nanjing 210096 (China)

    2016-04-11

    Complex automatic protection functions are being added to the onboard software of the Alpha Magnetic Spectrometer. A hardware-in-the-loop simulation method has been introduced to overcome the difficulties of ground testing that are brought by hardware and environmental limitations. We invented a time-saving approach by reusing the flight data as the data source of the simulation system instead of mathematical models. This is easy to implement and it works efficiently. This paper presents the system framework, implementation details and some application examples.

  6. User Context Aware Base Station Power Flow Model

    OpenAIRE

    Walsh, Barbara; Farrell, Ronan

    2005-01-01

    At present the testing of power amplifiers within base station transmitters is limited to testing at component level as opposed to testing at the system level. While the detection of catastrophic failure is possible, that of performance degradation is not. This paper proposes a base station model with respect to transmitter output power with the aim of introducing system level monitoring of the power amplifier behaviour within the base station. Our model reflects the expe...

  7. Optimization of station battery replacement

    International Nuclear Information System (INIS)

    Jancauskas, J.R.; Shook, D.A.

    1994-01-01

    During a loss of ac power at a nuclear generating station (including diesel generators), batteries provide the source of power which is required to operate safety-related components. Because traditional lead-acid batteries have a qualified life of 20 years, the batteries must be replaced a minimum of once during a station's lifetime, twice if license extension is pursued, and more often depending on actual in-service dates and the results of surveillance tests. Replacement of batteries often occurs prior to 20 years as a result of systems changes caused by factors such as Station Blackout Regulations, control system upgrades, incremental load growth, and changes in the operating times of existing equipment. Many of these replacement decisions are based on the predictive capabilities of manual design basis calculations. The inherent conservatism of manual calculations may result in battery replacements occurring before actually required. Computerized analysis of batteries can aid in optimizing the timing of replacements as well as in interpreting service test data. Computerized analysis also provides large benefits in maintaining the as-configured load profile and corresponding design margins, while also providing the capability of quickly analyze proposed modifications and response to internal and external audits

  8. Electrophysiological assessment of auditory processing disorder in children with non-syndromic cleft lip and/or palate.

    Science.gov (United States)

    Ma, Xiaoran; McPherson, Bradley; Ma, Lian

    2016-01-01

    Cleft lip and/or palate is a common congenital craniofacial malformation found worldwide. A frequently associated disorder is conductive hearing loss, and this disorder has been thoroughly investigated in children with non-syndromic cleft lip and/or palate (NSCL/P). However, analysis of auditory processing function is rarely reported for this population, although this issue should not be ignored since abnormal auditory cortical structures have been found in populations with cleft disorders. The present study utilized electrophysiological tests to assess the auditory status of a large group of children with NSCL/P, and investigated whether this group had less robust central auditory processing abilities compared to craniofacially normal children. 146 children with NSCL/P who had normal peripheral hearing thresholds, and 60 craniofacially normal children aged from 6 to 15 years, were recruited. Electrophysiological tests, including auditory brainstem response (ABR), P1-N1-P2 complex, and P300 component recording, were conducted. ABR and N1 wave latencies were significantly prolonged in children with NSCL/P. An atypical developmental trend was found for long latency potentials in children with cleft compared to control group children. Children with unilateral cleft lip and palate showed a greater level of abnormal results compared with other cleft subgroups, whereas the cleft lip subgroup had the most robust responses for all tests. Children with NSCL/P may have slower than normal neural transmission times between the peripheral auditory nerve and brainstem. Possible delayed development of myelination and synaptogenesis may also influence auditory processing function in this population. Present research outcomes were consistent with previous, smaller sample size, electrophysiological studies on infants and children with cleft lip/palate disorders. In view of the these findings, and reports of educational disadvantage associated with cleft disorders, further research

  9. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing

    NARCIS (Netherlands)

    Quinn, T. A.; Granite, S.; Allessie, M. A.; Antzelevitch, C.; Bollensdorff, C.; Bub, G.; Burton, R. A. B.; Cerbai, E.; Chen, P. S.; Delmar, M.; DiFrancesco, D.; Earm, Y. E.; Efimov, I. R.; Egger, M.; Entcheva, E.; Fink, M.; Fischmeister, R.; Franz, M. R.; Garny, A.; Giles, W. R.; Hannes, T.; Harding, S. E.; Hunter, P. J.; Iribe, G.; Jalife, J.; Johnson, C. R.; Kass, R. S.; Kodama, I.; Koren, G.; Lord, P.; Markhasin, V. S.; Matsuoka, S.; McCulloch, A. D.; Mirams, G. R.; Morley, G. E.; Nattel, S.; Noble, D.; Olesen, S. P.; Panfilov, A. V.; Trayanova, N. A.; Ravens, U.; Richard, S.; Rosenbaum, D. S.; Rudy, Y.; Sachs, F.; Sachse, F. B.; Saint, D. A.; Schotten, U.; Solovyova, O.; Taggart, P.; Tung, L.; Varró, A.; Volders, P. G.; Wang, K.; Weiss, J. N.; Wettwer, E.; White, E.; Wilders, R.; Winslow, R. L.; Kohl, P.

    2011-01-01

    Cardiac experimental electrophysiology is in need of a well-defined Minimum Information Standard for recording, annotating, and reporting experimental data. As a step towards establishing this, we present a draft standard, called Minimum Information about a Cardiac Electrophysiology Experiment

  10. Space Station solar water heater

    Science.gov (United States)

    Horan, D. C.; Somers, Richard E.; Haynes, R. D.

    1990-01-01

    The feasibility of directly converting solar energy for crew water heating on the Space Station Freedom (SSF) and other human-tended missions such as a geosynchronous space station, lunar base, or Mars spacecraft was investigated. Computer codes were developed to model the systems, and a proof-of-concept thermal vacuum test was conducted to evaluate system performance in an environment simulating the SSF. The results indicate that a solar water heater is feasible. It could provide up to 100 percent of the design heating load without a significant configuration change to the SSF or other missions. The solar heater system requires only 15 percent of the electricity that an all-electric system on the SSF would require. This allows a reduction in the solar array or a surplus of electricity for onboard experiments.

  11. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  12. Active Marine Station Metadata

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Active Marine Station Metadata is a daily metadata report for active marine bouy and C-MAN (Coastal Marine Automated Network) platforms from the National Data...

  13. Electrostatic pickup station

    CERN Multimedia

    CERN PhotoLab

    1982-01-01

    Electrostatic pickup station, with 4 interleaved electrodes, to measure beam position in the horizontal and vertical plane. This type is used in the transfer lines leaving the PS (TT2, TT70, TTL2). See also 7904075.

  14. Public Transit Stations

    Data.gov (United States)

    Department of Homeland Security — fixed rail transit stations within the Continental United States, Alaska, Hawaii, the District of Columbia, and Puerto Rico. The modes of transit that are serviced...

  15. Mukilteo Research Station

    Data.gov (United States)

    Federal Laboratory Consortium — Research at the Mukilteo Research Station focuses on understanding the life cycle of marine species and the impacts of ecosystem stressors on anadromous and marine...

  16. Maine Field Station

    Data.gov (United States)

    Federal Laboratory Consortium — In 2000 NOAA's National Marine Fisheries Service established the Maine Field Station in Orono, ME to have more direct involvement in the conservation of the living...

  17. FEMA DFIRM Station Start

    Data.gov (United States)

    Minnesota Department of Natural Resources — This table contains information about station starting locations. These locations indicate the reference point that was used as the origin for distance measurements...

  18. Natural Weathering Exposure Station

    Data.gov (United States)

    Federal Laboratory Consortium — The Corps of Engineers' Treat Island Natural Weathering Exposure Station is a long-term natural weathering facility used to study concrete durability. Located on the...

  19. Routes and Stations

    Data.gov (United States)

    Department of Homeland Security — he Routes_Stations table is composed of fixed rail transit systems within the Continental United States, Alaska, Hawaii, the District of Columbia, and Puerto Rico....

  20. USRCRN Station Information

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Documentation of United States Regional Climate Reference Network (USRCRN) installations in 2009. Installations documented are for USRCRN pilot project stations in...

  1. Haptic control of a pneumatic muscle actuator to provide resistance for simulated isokinetic exercise: Part I--dynamic test station and human quadriceps dynamic simulator.

    Science.gov (United States)

    Hall, Kara L; Phillips, Chandler A; Reynolds, David B; Mohler, Stanley R; Rogers, Dana B; Neidhard-Doll, Amy T

    2014-01-01

    Pneumatic muscle actuators (PMAs) have a high power to weight ratio and possess unique characteristics which make them ideal actuators for applications involving human interaction. PMAs are difficult to control due to nonlinear dynamics, presenting challenges in system implementation. Despite these challenges, PMAs have great potential as a source of resistance for strength training and rehabilitation. The objective of this work was to control a PMA for use in isokinetic exercise, potentially benefiting anyone in need of optimal strength training through a joint's range of motion. A human quadriceps dynamic simulator (HQDS) was developed so that control effectiveness and accommodation could be tested prior to human implementation. The experimental set-up and HQDS are discussed in Part I of this work. The development of a PMA haptic controller and its interaction with the HQDS are discussed in Part II.

  2. Gas Stations, US, 2010, NAVTEQ

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Gas_Stations dataset is derived from the Navteq 'AUTOSVC' SDC layer (FAC_TYPE=5540) and contains gas stations and petrol stations. This NAVTEQ dataset is...

  3. Enhanced Master Station History Report

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Enhanced Master Station History Report (EMSHR) is a compiled list of basic, historical information for every station in the station history database, beginning...

  4. Tobruk power station

    Energy Technology Data Exchange (ETDEWEB)

    Boergardts, B

    1978-01-01

    In February of 1975, the Electricity Corporation Benghazi (ECB) awarded a contract for the construction of a turnkey power station and seawater desalination plant in Tobruk, Libya to a consortium under the leadership of BBC Mannheim. This power station has an output of 129 MW and supplies about 24,000 m/sup 3/ of drinking water daily. It went into operation in 1977, two and a half years after the contract was awarded.

  5. Leadership at Antarctic Stations.

    Science.gov (United States)

    1987-03-01

    Claseification 6. No. Pegees LEADERSHIP AT ANTARTIC STATIONS hxIs i4 5, C =r~eta(C), 17 Rfs~W (R, Udusiied U)J 7. No Refs 8. Author(s) Edocumesnt I...whether there is a "best" approach to leadership at an Antartic Station and what leadership style may have the most to offer. 3~~ __ ___ Tipesis to be

  6. A suspended act: increased reflectivity and gender-dependent electrophysiological change following Quadrato Motor Training.

    Science.gov (United States)

    Ben-Soussan, Tal Dotan; Berkovich-Ohana, Aviva; Glicksohn, Joseph; Goldstein, Abraham

    2014-01-01

    Quadrato Motor Training (QMT) is a specifically-structured walking meditation, aimed at improving reflectivity and lowering habitual thought and movement. Here we set out to examine the possible effect of QMT on reflectivity, employing the Hidden Figures Test (HFT), which assesses both spatial performance (measured by correct answers) as well as reflectivity (interpolated from correct answers and reaction time). In the first study (n = 24, only females), we showed that QMT significantly improves HFT performance, compared to two groups, controlling for cognitive or motor aspects of the QMT: Verbal Training (identical cognitive training with verbal response) and Simple Motor Training (similar motor training with reduced choice requirements). These results show that QMT improves HFT performance above the pre-post expected learning. In the second study, building on previous literature showing gender-dependent effects on cognitive performance, we conducted a preliminary pilot examining gender-dependent effect of training on reflectivity and its electrophysiological counterparts. EEG analyses focused on theta, alpha and gamma coherence. HFT performance and resting-state EEG were measured in 37 participants (20 males), using a within-subject pre-post design. Following training, HFT performance improved in both genders. However, we found a gender-dependent difference in functional connectivity: while theta and alpha intra-hemispheric coherence was enhanced in females, the opposite pattern was found in males. These results are discussed in relation to neuronal efficiency theory. Together, the results demonstrate that QMT improves spatial performance, and may involve a gender-dependent electrophysiological effect. This study emphasizes both the importance of studying gender-related training effects within the contemplative neuroscience endeavor, as well as the need to widen its scope toward including "contemplation in action."

  7. Electrophysiologic alterations in the excitability of the sciatic and vagus nerves during early stages of sepsis.

    Science.gov (United States)

    Diniz, Lúcio Ricardo Leite; Portella, Viviane Gomes; da Silva Alves, Kerly Shamira; Araújo, Pâmella Cristina da Costa; de Albuquerque Júnior, Ricardo Luiz Cavalcanti; Cavalcante de Albuquerque, Aline Alice; Coelho-de-Souza, Andrelina Noronha; Leal-Cardoso, José Henrique

    2018-01-01

    Nonspecific and delayed diagnosis of neurologic damage contributes to the development of neuropathies in patients with severe sepsis. The present study assessed the electrophysiologic parameters related to the excitability and conductibility of sciatic and vagus nerves during early stages of sepsis. Twenty-four hours after sepsis induced by cecal ligation and puncture (CLP) model, sciatic and vagus nerves of septic (CLP group) and control (sham group) rats were removed, and selected electric stimulations were applied to measure the parameters of the first and second components of the compound action potential. The first component originated from fibers with motor and sensory functions (Types A α and A β fibers) with a large conduction velocity (70-120 m/s), and the second component originated from fibers (Type A γ ) with sensorial function. To evaluate the presence of sensorial alterations, the sensitivity to non-noxious mechanical stimuli was measured by using the von Frey test. Hematoxylin and eosin staining of the nerves was performed. We observed an increase of rheobase followed by a decrease in the first component amplitude and a higher paw withdrawal threshold in response to the application of von Frey filaments in sciatic nerves from the CLP group compared to the sham group. Differently, a decrease in rheobase and an increase in the first component amplitude of vagal C fibers from CLP group were registered. No significant morphologic alteration was observed. Our data showed that the electrophysiologic alterations in peripheral nerves vary with the fiber type and might be identified in the first 24 h of sepsis, before clinical signs of neuromuscular disorders.

  8. Behavioral and electrophysiological studies of radiation detection in a freshwater crustacean

    International Nuclear Information System (INIS)

    Rodriguez, A.; Kimeldorf, D.J.

    1976-01-01

    Behavioral and electrophysiological studies were done on the crayfish (Pacifastacus trowbridgii Stimpson) to determine its ability to detect exposure to 300 kVp x rays. Behavioral arousal responses were observed at exposure rates of 10 to 30 R/sec. Wholebody and partial-body exposures of eye-stalkless (blinded) animals also induced similar responses and indicated a radiation-sensitive receptor in the abdomen. Prolonged exposure under free choice of residence conditions induced an avoidance of the x-ray field. X-ray exposure of the dark-adapted compound eye evoked an electroretinogram (ERG) that was similar to the light-evoked ERG. The ERG amplitude was directly proportional to the total exposure with exposures less than 300 msec duration and related to the logarithm of the exposure rate with exposures greater than 300 msec. X-ray exposure of receptor sites on the medial branch of the antennule and the cheliped of the first walking-leg did not yield any significant chemoreceptor responses as judged by electrophysiological tests. X-irradiation of the sixth abdominal ganglion in both isolated and in vivo preparations elicited significant increases in neural impulse activity. The latency varied inversely with exposure rate. Spike potentials evoked by x rays were similar to those evoked by light; however, a supplemental increase in spikes of lower amplitude occurred that did not occur during light stimulation. It appears likely that the behavioral response in the crayfish, subjected to abdomen-only exposure, may be instigated by x-ray excitation of the sixth ganglion

  9. The Princess Elisabeth Station

    Science.gov (United States)

    Berte, Johan

    2012-01-01

    Aware of the increasing impact of human activities on the Earth system, Belgian Science Policy Office (Belspo) launched in 1997 a research programme in support of a sustainable development policy. This umbrella programme included the Belgian Scientific Programme on Antarctic Research. The International Polar Foundation, an organization led by the civil engineer and explorer Alain Hubert, was commissioned by the Belgian Federal government in 2004 to design, construct and operate a new Belgian Antarctic Research Station as an element under this umbrella programme. The station was to be designed as a central location for investigating the characteristic sequence of Antarctic geographical regions (polynia, coast, ice shelf, ice sheet, marginal mountain area and dry valleys, inland plateau) within a radius of 200 kilometers (approx.124 miles) of a selected site. The station was also to be designed as "state of the art" with respect to sustainable development, energy consumption, and waste disposal, with a minimum lifetime of 25 years. The goal of the project was to build a station and enable science. So first we needed some basic requirements, which I have listed here; plus we had to finance the station ourselves. Our most important requirement was that we decided to make it a zero emissions station. This was both a philosophical choice as we thought it more consistent with Antarctic Treaty obligations and it was also a logistical advantage. If you are using renewable energy sources, you do not have to bring in all the fuel.

  10. Pengujian sifat unggul beberapa klon harapan kopi arabika di kebun percobaan Andungsari, Jawa Timur (Testing for superior traits of some arabica coffee promising clones at Andungsari research station, East Java

    Directory of Open Access Journals (Sweden)

    Retno Hulupi

    2012-08-01

    Full Text Available One of the major diseases which limiting production in arabica coffee is the leaf rust caused by the fungus Hemileia vastatrix, B et Br. Selection and testing on thirteen promising arabica coffee clones were carried out at endemic area for leaf rust disease, Andungsari Research Station, for six fruiting times. The aims of these test were to find out superior planting material as clone with genetic resistance to leaf rust. As the beverage commodities, criterium selections for superiority clone besides resistant to leaf rust and yielding ability of more than 1,5 ton/ha also must be excellent in cup quality. Under this consideration, BP 416 A clone showed as the best high yielding ability i.e. 1,595 kg/ha and stable, besides resistant to leaf rust disease compared to the other clones tested. This clone had good cup quality, better than earlier released variety such as USDA 762 and S 795 although was not better than Andungsari 1 that were planted in the same location. The best physical bean characteristics was obtained on BP 513 A clone wich is derived from S 795 x Caturra red, having 89.2% of normal bean and 18.3% outurn characteristics. However, due to lower yielding and more susceptible to leaf rust, this clone could not be classified as superior clone.

  11. Software development assurance for special control computer sets on the base of the Electronica-60M microcomputer in the stations of fuel element nondestructive testing

    International Nuclear Information System (INIS)

    Vasil'kova, A.D.; Grachev, S.N.; Salakatova, L.S.

    1987-01-01

    A special computational control complex (SCCC) including the ''Elektronika-60M'' microcomputer, a device for communication with an object (DCO) based on the typical microprocessing set (TMS) based on LIUS-2 KTS means and an adapter for communication of the ''Elektronika-60M'' microcomputer bus with IK1 TMS bus developed for their conjugation is used for development of nondestructive control post software. An instrumental SCCC including SM-4 microcomputer, TMS units as DCO, an adapter for communication of the common bus of the SM-4 minicomputer with the IK1 TMS bus developed for their conjugation and devices for simulation of the facility operation is suggested to increase labour productivity of programmers. The SM-4 microcomputer permits to develop programs in the FORTRAN language and to carry out their effective adjustment. A subprogram library for communication with TMS units is compiled, and the technique for testing FORTRAN programs in programmable read-only memory TMS as well as start of these programs are developed

  12. The risk of leukaemia in young children from exposure to tritium and carbon-14 in the discharges of German nuclear power stations and in the fallout from atmospheric nuclear weapons testing.

    Science.gov (United States)

    Wakeford, Richard

    2014-05-01

    Towards the end of 2007, the results were published from a case-control study (the "KiKK Study") of cancer in young children, diagnosed study found a tendency for cases of leukaemia to live closer to the nearest nuclear power station than their matched controls, producing an odds ratio that was raised to a statistically significant extent for residence within 5 km of a nuclear power station. The findings of the study received much publicity, but a detailed radiological risk assessment demonstrated that the radiation doses received by young children from discharges of radioactive material from the nuclear reactors were much lower than those received from natural background radiation and far too small to be responsible for the statistical association reported in the KiKK Study. This has led to speculation that conventional radiological risk assessments have grossly underestimated the risk of leukaemia in young children posed by exposure to man-made radionuclides, and particular attention has been drawn to the possible role of tritium and carbon-14 discharges in this supposedly severe underestimation of risk. Both (3)H and (14)C are generated naturally in the upper atmosphere, and substantial increases in these radionuclides in the environment occurred as a result of their production by atmospheric testing of nuclear weapons during the late 1950s and early 1960s. If the leukaemogenic effect of these radionuclides has been seriously underestimated to the degree necessary to explain the KiKK Study findings, then a pronounced increase in the worldwide incidence of leukaemia among young children should have followed the notably elevated exposure to (3)H and (14)C from nuclear weapons testing fallout. To investigate this hypothesis, the time series of incidence rates of leukaemia among young children risk of leukaemia in young children following the peak of above-ground nuclear weapons testing, or that incidence rates are related to level of exposure to fallout, is

  13. Electrophysiologic studies of the thoracic limb of the horse.

    Science.gov (United States)

    Blythe, L L; Kitchell, R L

    1982-09-01

    The cutaneous innervation of the thoracic limb was investigated in 18 barbiturate-anesthetized horses, using electrophysiologic techniques. The cutaneous area (CA) innervated by each cutaneous nerve was delineated in at least 4 horses by stroking the hairs with a small watercolor brush while recording from the nerve. Mapping of adjacent CA revealed areas of considerable overlap. The part of a CA of a given nerve supplied only by that nerve is referred to as its autonomous zone (AZ). In contrast to the standard textbook illustrations cutaneous branches of the axillary, radial, musculocutaneous, and ulnar nerves overlapped extensively in the antebrachium. Clinically testable AZ were found in the antebrachium for the caudal cutaneous antebrachial nerve of the ulnar nerve and in the carpus and manus for the cutaneous branches of the median, ulnar, and musculocutaneous nerves; AZ were not found for the cutaneous branches of the radial and axillary nerves.

  14. Electrophysiology of blunted emotional bias in psychopathic personality.

    Science.gov (United States)

    Carolan, Patrick L; Jaspers-Fayer, Fern; Asmaro, Deyar T; Douglas, Kevin S; Liotti, Mario

    2014-01-01

    Diminished emotional capacity is a core characteristic of psychopathic personality. We examined behavioral and electrophysiological differences in attentional bias to emotional material in 34 healthy individuals rated high or low in psychopathic traits using the short form of the Psychopathic Personality Inventory-Revised (18 high-trait, 16 low-trait). While performing an emotional Stroop task, high-trait participants displayed reduced emotional modulation of the late positive potential (LPP, 400-600 ms), and early anterior positivity (EAP, 200-300 ms) amplitudes. Results suggest blunted bias to affective content in psychopathic personality, characterized by diminished early capture to emotional salience (EAP) and dampened cognitive emotional processing (LPP). Copyright © 2013 Society for Psychophysiological Research.

  15. The up and down of sleep: From molecules to electrophysiology.

    Science.gov (United States)

    Navarro-Lobato, Irene; Genzel, Lisa

    2018-03-12

    Alternations of up and down can be seen across many different levels during sleep. Neural firing-rates, synaptic markers, molecular pathways, and gene expression all show differential up and down regulation across brain areas and sleep stages. And also the hallmarks of sleep - sleep stage specific oscillations - are characterized themselves by up and down as seen within the slow oscillation or theta cycles. In this review, we summarize the up and down of sleep covering molecules to electrophysiology and present different theories how this up and down could be regulated by the up and down of sleep oscillations. Further, we propose a tentative theory how this differential up and down could contribute to various outcomes of sleep related memory consolidation: enhancement of hippocampal representations of very novel memories and cortical consolidation of memories congruent with previous knowledge-networks. Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

  16. Extracellular Electrophysiological Measurements of Cooperative Signals in Astrocytes Populations

    Science.gov (United States)

    Mestre, Ana L. G.; Inácio, Pedro M. C.; Elamine, Youssef; Asgarifar, Sanaz; Lourenço, Ana S.; Cristiano, Maria L. S.; Aguiar, Paulo; Medeiros, Maria C. R.; Araújo, Inês M.; Ventura, João; Gomes, Henrique L.

    2017-01-01

    Astrocytes are neuroglial cells that exhibit functional electrical properties sensitive to neuronal activity and capable of modulating neurotransmission. Thus, electrophysiological recordings of astroglial activity are very attractive to study the dynamics of glial signaling. This contribution reports on the use of ultra-sensitive planar electrodes combined with low noise and low frequency amplifiers that enable the detection of extracellular signals produced by primary cultures of astrocytes isolated from mouse cerebral cortex. Recorded activity is characterized by spontaneous bursts comprised of discrete signals with pronounced changes on the signal rate and amplitude. Weak and sporadic signals become synchronized and evolve with time to higher amplitude signals with a quasi-periodic behavior, revealing a cooperative signaling process. The methodology presented herewith enables the study of ionic fluctuations of population of cells, complementing the single cells observation by calcium imaging as well as by patch-clamp techniques. PMID:29109679

  17. Alternans promotion in cardiac electrophysiology models by delay differential equations.

    Science.gov (United States)

    Gomes, Johnny M; Dos Santos, Rodrigo Weber; Cherry, Elizabeth M

    2017-09-01

    Cardiac electrical alternans is a state of alternation between long and short action potentials and is frequently associated with harmful cardiac conditions. Different dynamic mechanisms can give rise to alternans; however, many cardiac models based on ordinary differential equations are not able to reproduce this phenomenon. A previous study showed that alternans can be induced by the introduction of delay differential equations (DDEs) in the formulations of the ion channel gating variables of a canine myocyte model. The present work demonstrates that this technique is not model-specific by successfully promoting alternans using DDEs for five cardiac electrophysiology models that describe different types of myocytes, with varying degrees of complexity. By analyzing results across the different models, we observe two potential requirements for alternans promotion via DDEs for ionic gates: (i) the gate must have a significant influence on the action potential duration and (ii) a delay must significantly impair the gate's recovery between consecutive action potentials.

  18. Electrophysiological correlates of error processing in borderline personality disorder.

    Science.gov (United States)

    Ruchsow, Martin; Walter, Henrik; Buchheim, Anna; Martius, Philipp; Spitzer, Manfred; Kächele, Horst; Grön, Georg; Kiefer, Markus

    2006-05-01

    The electrophysiological correlates of error processing were investigated in patients with borderline personality disorder (BPD) using event-related potentials (ERP). Twelve patients with BPD and 12 healthy controls were additionally rated with the Barratt impulsiveness scale (BIS-10). Participants performed a Go/Nogo task while a 64 channel EEG was recorded. Three ERP components were of special interest: error-related negativity (ERN)/error negativity (Ne), early error positivity (early Pe) reflecting automatic error processing, and the late Pe component which is thought to mirror the awareness of erroneous responses. We found smaller amplitudes of the ERN/Ne in patients with BPD compared to controls. Moreover, significant correlations with the BIS-10 non-planning sub-score could be demonstrated for both the entire group and the patient group. No between-group differences were observed for the early and late Pe components. ERP measures appear to be a suitable tool to study clinical time courses in BPD.

  19. Alternans promotion in cardiac electrophysiology models by delay differential equations

    Science.gov (United States)

    Gomes, Johnny M.; dos Santos, Rodrigo Weber; Cherry, Elizabeth M.

    2017-09-01

    Cardiac electrical alternans is a state of alternation between long and short action potentials and is frequently associated with harmful cardiac conditions. Different dynamic mechanisms can give rise to alternans; however, many cardiac models based on ordinary differential equations are not able to reproduce this phenomenon. A previous study showed that alternans can be induced by the introduction of delay differential equations (DDEs) in the formulations of the ion channel gating variables of a canine myocyte model. The present work demonstrates that this technique is not model-specific by successfully promoting alternans using DDEs for five cardiac electrophysiology models that describe different types of myocytes, with varying degrees of complexity. By analyzing results across the different models, we observe two potential requirements for alternans promotion via DDEs for ionic gates: (i) the gate must have a significant influence on the action potential duration and (ii) a delay must significantly impair the gate's recovery between consecutive action potentials.

  20. Frontal negativity: An electrophysiological index of interpersonal guilt.

    Science.gov (United States)

    Leng, Bingbing; Wang, Xiangling; Cao, Bihua; Li, Fuhong

    2017-12-01

    The present study aimed to reveal the temporal course and electrophysiological correlates of interpersonal guilt. Human participants were asked to perform multiple rounds of a dot-estimation task with their partners, while event-related potential being recorded. The paired participants were informed that they would win money if both responded correctly; otherwise, both of them would lose money. The feeling of guilt in Self-Wrong condition (SW) was significantly higher than that in Both-Wrong and Partner-Wrong conditions. At approximately 350 ms after the onset of feedback presentation, greater negativities were observed in the frontal regions in the guilt condition (i.e., SW) than those in the non-guilt condition. The guilt-modulated frontal negativity might reflect the interactions of self-reflection, condemnation, and negative emotion.

  1. Seismometer array station processors

    International Nuclear Information System (INIS)

    Key, F.A.; Lea, T.G.; Douglas, A.

    1977-01-01

    A description is given of the design, construction and initial testing of two types of Seismometer Array Station Processor (SASP), one to work with data stored on magnetic tape in analogue form, the other with data in digital form. The purpose of a SASP is to detect the short period P waves recorded by a UK-type array of 20 seismometers and to edit these on to a a digital library tape or disc. The edited data are then processed to obtain a rough location for the source and to produce seismograms (after optimum processing) for analysis by a seismologist. SASPs are an important component in the scheme for monitoring underground explosions advocated by the UK in the Conference of the Committee on Disarmament. With digital input a SASP can operate at 30 times real time using a linear detection process and at 20 times real time using the log detector of Weichert. Although the log detector is slower, it has the advantage over the linear detector that signals with lower signal-to-noise ratio can be detected and spurious large amplitudes are less likely to produce a detection. It is recommended, therefore, that where possible array data should be recorded in digital form for input to a SASP and that the log detector of Weichert be used. Trial runs show that a SASP is capable of detecting signals down to signal-to-noise ratios of about two with very few false detections, and at mid-continental array sites it should be capable of detecting most, if not all, the signals with magnitude above msub(b) 4.5; the UK argues that, given a suitable network, it is realistic to hope that sources of this magnitude and above can be detected and identified by seismological means alone. (author)

  2. Central vs. peripheral neuraxial sympathetic control of porcine ventricular electrophysiology

    Science.gov (United States)

    Yamakawa, Kentaro; Howard-Quijano, Kimberly; Zhou, Wei; Rajendran, Pradeep; Yagishita, Daigo; Vaseghi, Marmar; Ajijola, Olujimi A.; Armour, J. Andrew; Shivkumar, Kalyanam; Ardell, Jeffrey L.

    2015-01-01

    Sympathoexcitation is associated with ventricular arrhythmogenesis. The aim of this study was to determine the role of thoracic dorsal root afferent neural inputs to the spinal cord in modulating ventricular sympathetic control of normal heart electrophysiology. We hypothesize that dorsal root afferent input tonically modulates basal and evoked efferent sympathetic control of the heart. A 56-electrode sock placed on the epicardial ventricle in anesthetized Yorkshire pigs (n = 17) recorded electrophysiological function, as well as activation recovery interval (ARI) and dispersion in ARI, at baseline conditions and during stellate ganglion electrical stimulation. Measures were compared between intact states and sequential unilateral T1–T4 dorsal root transection (DRTx), ipsilateral ventral root transection (VRTx), and contralateral dorsal and ventral root transections (DVRTx). Left or right DRTx decreased global basal ARI [Lt.DRTx: 369 ± 12 to 319 ± 13 ms (P < 0.01) and Rt.DRTx: 388 ± 19 to 356 ± 15 ms (P < 0.01)]. Subsequent unilateral VRTx followed by contralateral DRx+VRTx induced no further change. In intact states, left and right stellate ganglion stimulation shortened ARIs (6 ± 2% vs. 17 ± 3%), while increasing dispersion (+139% vs. +88%). There was no difference in magnitude of ARI or dispersion change with stellate stimulation following spinal root transections. Interruption of thoracic spinal afferent signaling results in enhanced basal cardiac sympathoexcitability without diminishing the sympathetic response to stellate ganglion stimulation. This suggests spinal dorsal root transection releases spinal cord-mediated tonic inhibitory control of efferent sympathetic tone, while maintaining intrathoracic cardiocentric neural networks. PMID:26661096

  3. Novel electrophysiological approaches to clinical epilepsy. Diagnosis and treatment

    International Nuclear Information System (INIS)

    Kanazawa, Kyoko; Matsumoto, Riki; Ikeda, Akio; Kinoshita, Masako

    2011-01-01

    Seizure onset zone (SOZ) is currently defined by ictal epileptiform discharges, which are most commonly recorded as regional low-voltage fast waves or repetitive spikes. Interictal epileptiform discharges, on the other hand, are not specific enough for SOZ as they are recorded at zones other than the SOZ; they are also recorded from areas that do not generate the ictal pattern and from areas to which ictal discharges propagate. Besides spikes and sharp waves, a novel index of human epileptogenicity has been investigated in association with wide-band electroencephalography (EEG) analysis. We primarily noted the following during clinical neurophysiological analysis for clinical epilepsy. Recent development of digital EEG technology enabled us to record wide-band EEG in a clinical setting. Thus, high frequency (>200 Hz) and low frequency (<1 Hz) components can be reliably recorded using subdural electrodes. Direct current shift, slow shift, ripple, and fast ripple can be well delineated, and they will be potentially useful in the diagnosis and management of epileptic patients. Fiber tractography (morphological parameter) and cortico-cortical-evoked potentials with single cortical stimulation (electrophysiological parameter) elucidated cortico-cortical connections in human brain. The data thus obtained can help us understand the mechanism of seizure propagation and normal cortical functional connectivity. Non-invasive simultaneous recording of EEG and functional magnetic resonance imaging (fMRI) provided information on the roles of deep brain structures associated with scalp-recorded epileptiform discharges. Interventional neurophysiology can shed light on the non-pharmacological treatment of epilepsy. In this report, we discuss these novel electrophysiological approaches to the diagnosis and treatment of clinical epilepsy. (author)

  4. Electrophysiological mechanisms of sophocarpine as a potential antiarrhythmic agent.

    Science.gov (United States)

    Yang, Zhi-fang; Li, Ci-zhen; Wang, Wei; Chen, Ying-min; Zhang, Ying; Liu, Yuan-mou; Wang, Hong-wei

    2011-03-01

    To examine the electrophysiological effects of sophocarpine on action potentials (AP) and ionic currents of cardiac myocytes and to compare some of these effects with those of amiodarone. Langendorff perfusion set-up was used in isolated guinea pig heart, and responses to sophocarpine were monitored using electrocardiograph. Conventional microelectrode, voltage clamp technique and perforated patch were employed to record fast response AP (fAP), slow response AP (sAP) and ionic currents in guinea pig papillary muscle or rabbit sinus node cells. Tachyarrhythmia produced by isoprenaline (15 μmol/L) could be reversed by sophocarpine (300 μmol/L). Sophocarpine (10 μmol/L) decreased the amplitude by 4.0%, maximal depolarization velocity (V(max)) of the fAP by 24.4%, and Na(+) current (I(Na)) by 18.0%, while it prolonged the effective refractory period (ERP) by 21.1%. The same concentration of sophocarpine could also decrease the amplitude and V(max) of the sAP, by 26.8% and 25.7%, respectively, and attenuated the Ca(2+) current (I(CaL)) and the K(+) tail current substantially. Comparison of sophocarpine with amiodarone demonstrated that both prolonged the duration and the ERP of fAP and sAP, both decreased the amplitude and V(max) of the fAP and sAP, and both slowed the automatic heart rate. Sophocarpine could reverse isoprenaline-induced arrhythmia and inhibit I(Na), I(CaL), and I(Kr) currents. The electrophysiological effects of sophocarpine are similar to those of amiodarone, which might be regarded as a prospective antiarrhythmic agent.

  5. Reentrant Information Flow in Electrophysiological Rat Default Mode Network.

    Science.gov (United States)

    Jing, Wei; Guo, Daqing; Zhang, Yunxiang; Guo, Fengru; Valdés-Sosa, Pedro A; Xia, Yang; Yao, Dezhong

    2017-01-01

    Functional MRI (fMRI) studies have demonstrated that the rodent brain shows a default mode network (DMN) activity similar to that in humans, offering a potential preclinical model both for physiological and pathophysiological studies. However, the neuronal mechanism underlying rodent DMN remains poorly understood. Here, we used electrophysiological data to analyze the power spectrum and estimate the directed phase transfer entropy (dPTE) within rat DMN across three vigilance states: wakeful rest (WR), slow-wave sleep (SWS), and rapid-eye-movement sleep (REMS). We observed decreased gamma powers during SWS compared with WR in most of the DMN regions. Increased gamma powers were found in prelimbic cortex, cingulate cortex, and hippocampus during REMS compared with WR, whereas retrosplenial cortex showed a reverse trend. These changed gamma powers are in line with the local metabolic variation of homologous brain regions in humans. In the analysis of directional interactions, we observed well-organized anterior-to-posterior patterns of information flow in the delta band, while opposite patterns of posterior-to-anterior flow were found in the theta band. These frequency-specific opposite patterns were only observed in WR and REMS. Additionally, most of the information senders in the delta band were also the receivers in the theta band, and vice versa. Our results provide electrophysiological evidence that rat DMN is similar to its human counterpart, and there is a frequency-dependent reentry loop of anterior-posterior information flow within rat DMN, which may offer a mechanism for functional integration, supporting conscious awareness.

  6. A Wireless Headstage for Combined Optogenetics and Multichannel Electrophysiological Recording.

    Science.gov (United States)

    Gagnon-Turcotte, Gabriel; LeChasseur, Yoan; Bories, Cyril; Messaddeq, Younes; De Koninck, Yves; Gosselin, Benoit

    2017-02-01

    This paper presents a wireless headstage with real-time spike detection and data compression for combined optogenetics and multichannel electrophysiological recording. The proposed headstage, which is intended to perform both optical stimulation and electrophysiological recordings simultaneously in freely moving transgenic rodents, is entirely built with commercial off-the-shelf components, and includes 32 recording channels and 32 optical stimulation channels. It can detect, compress and transmit full action potential waveforms over 32 channels in parallel and in real time using an embedded digital signal processor based on a low-power field programmable gate array and a Microblaze microprocessor softcore. Such a processor implements a complete digital spike detector featuring a novel adaptive threshold based on a Sigma-delta control loop, and a wavelet data compression module using a new dynamic coefficient re-quantization technique achieving large compression ratios with higher signal quality. Simultaneous optical stimulation and recording have been performed in-vivo using an optrode featuring 8 microelectrodes and 1 implantable fiber coupled to a 465-nm LED, in the somatosensory cortex and the Hippocampus of a transgenic mouse expressing ChannelRhodospin (Thy1::ChR2-YFP line 4) under anesthetized conditions. Experimental results show that the proposed headstage can trigger neuron activity while collecting, detecting and compressing single cell microvolt amplitude activity from multiple channels in parallel while achieving overall compression ratios above 500. This is the first reported high-channel count wireless optogenetic device providing simultaneous optical stimulation and recording. Measured characteristics show that the proposed headstage can achieve up to 100% of true positive detection rate for signal-to-noise ratio (SNR) down to 15 dB, while achieving up to 97.28% at SNR as low as 5 dB. The implemented prototype features a lifespan of up to 105

  7. Toluene stability Space Station Rankine power system

    Science.gov (United States)

    Havens, V. N.; Ragaller, D. R.; Sibert, L.; Miller, D.

    1987-01-01

    A dynamic test loop is designed to evaluate the thermal stability of an organic Rankine cycle working fluid, toluene, for potential application to the Space Station power conversion unit. Samples of the noncondensible gases and the liquid toluene were taken periodically during the 3410 hour test at 750 F peak temperature. The results obtained from the toluene stability loop verify that toluene degradation will not lead to a loss of performance over the 30-year Space Station mission life requirement. The identity of the degradation products and the low rates of formation were as expected from toluene capsule test data.

  8. Effects of 2G and 3G mobile phones on performance and electrophysiology in adolescents, young adults and older adults.

    Science.gov (United States)

    Leung, S; Croft, R J; McKenzie, R J; Iskra, S; Silber, B; Cooper, N R; O'Neill, B; Cropley, V; Diaz-Trujillo, A; Hamblin, D; Simpson, D

    2011-11-01

    This study examined sensory and cognitive processing in adolescents, young adults and older adults, when exposed to 2nd (2G) and 3rd (3G) generation mobile phone signals. Tests employed were the auditory 3-stimulus oddball and the N-back. Forty-one 13-15 year olds, forty-two 19-40 year olds and twenty 55-70 year olds were tested using a double-blind cross-over design, where each participant received Sham, 2G and 3G exposures, separated by at least 4 days. 3-Stimulus oddball task: Behavioural: accuracy and reaction time of responses to targets were not affected by exposure. Electrophysiological: augmented N1 was found in the 2G condition (independent of age group). N-back task: Behavioural: the combined groups performed less accurately during the 3G exposure (compared to Sham), with post hoc tests finding this effect separately in the adolescents only. Electrophysiological: delayed ERD/ERS responses of the alpha power were found in both 3G and 2G conditions (compared to Sham; independent of age group). Employing tasks tailored to each individual's ability level, this study provides support for an effect of acute 2G and 3G exposure on human cognitive function. The subtlety of mobile phone effect on cognition in our study suggests that it is important to account for individual differences in future mobile phone research. Copyright © 2011 International Federation of Clinical Neurophysiology. All rights reserved.

  9. UMTS Network Stations

    Science.gov (United States)

    Hernandez, C.

    2010-09-01

    The weakness of small island electrical grids implies a handicap for the electrical generation with renewable energy sources. With the intention of maximizing the installation of photovoltaic generators in the Canary Islands, arises the need to develop a solar forecasting system that allows knowing in advance the amount of PV generated electricity that will be going into the grid, from the installed PV power plants installed in the island. The forecasting tools need to get feedback from real weather data in "real time" from remote weather stations. Nevertheless, the transference of this data to the calculation computer servers is very complicated with the old point to point telecommunication systems that, neither allow the transfer of data from several remote weather stations simultaneously nor high frequency of sampling of weather parameters due to slowness of the connection. This one project has developed a telecommunications infrastructure that allows sensorizadas remote stations, to send data of its sensors, once every minute and simultaneously, to the calculation server running the solar forecasting numerical models. For it, the Canary Islands Institute of Technology has added a sophisticated communications network to its 30 weather stations measuring irradiation at strategic sites, areas with high penetration of photovoltaic generation or that have potential to host in the future photovoltaic power plants connected to the grid. In each one of the stations, irradiance and temperature measurement instruments have been installed, over inclined silicon cell, global radiation on horizontal surface and room temperature. Mobile telephone devices have been installed and programmed in each one of the weather stations, which allow the transfer of their data taking advantage of the UMTS service offered by the local telephone operator. Every minute the computer server running the numerical weather forecasting models receives data inputs from 120 instruments distributed

  10. Stage measurement at gaging stations

    Science.gov (United States)

    Sauer, Vernon B.; Turnipseed, D. Phil

    2010-01-01

    Stream and reservoir stage are critical parameters in the computation of stream discharge and reservoir volume, respectively. In addition, a record of stream stage is useful in the design of structures that may be affected by stream elevation, as well as for the planning for various uses of flood plains. This report describes equipment and methodology for the observation, sensing, and recording of stage in streams and reservoirs. Although the U.S. Geological Survey (USGS) still uses the traditional, basic stilling-well float system as a predominant gaging station, modern electronic stage sensors and water-level recorders are now commonly used. Bubble gages coupled with nonsubmersible pressure transducers eliminate the need for stilling wells. Submersible pressure transducers have become common in use for the measurement of stage in both rivers and lakes. Furthermore, noncontact methods, such as radar, acoustic, and laser methods of sensing water levels, are being developed and tested, and in the case of radar, are commonly used for the measurement of stage. This report describes commonly used gaging-station structures, as well as the design and operation of gaging stations. Almost all of the equipment and instruments described in this report will meet the accuracy standard set by the USGS Office of Surface Water (OSW) for the measurement of stage for most applications, which is ±0.01 foot (ft) or 0.2 percent of the effective stage. Several telemetry systems are used to transmit stage data from the gaging station to the office, although satellite telemetry has become the standard. These telemetry systems provide near real-time stage data, as well as other information that alerts the hydrographer to extreme or abnormal events, and instrument malfunctions.

  11. Study of the mechanical properties of the electric power station components: the punch test; Etude des proprietes mecaniques des composants de centrales thermiques: l'essai punch test

    Energy Technology Data Exchange (ETDEWEB)

    Isselin, J

    2003-03-15

    The aging of the electric production park implies an increasing need of knowledge concerning the evolution of the mechanical properties of its components. With regard to this problem, the availability in material is more and more small. This work proposes to characterize these properties through a mechanical test called Punch test. The main characteristic of this test is to use very small volume samples. The development of this test has been carried out by the study of a 15 MDV 4-05 steel coming from a steam drum of a thermal power plant after 145000 hours of service. At first, we have measured the influence of the parameters of this test. Then, the study has dealt more particularly on the transition temperature of the material. With the finite element simulation method, the strain hardening coefficient of the material has been determined. (O.M.)

  12. Hydrogen Fuelling Stations

    DEFF Research Database (Denmark)

    Rothuizen, Erasmus Damgaard

    . A system consisting of one high pressure storage tank is used to investigate the thermodynamics of fuelling a hydrogen vehicle. The results show that the decisive parameter for how the fuelling proceeds is the pressure loss in the vehicle. The single tank fuelling system is compared to a cascade fuelling......This thesis concerns hydrogen fuelling stations from an overall system perspective. The study investigates thermodynamics and energy consumption of hydrogen fuelling stations for fuelling vehicles for personal transportation. For the study a library concerning the components in a hydrogen fuelling...... station has been developed in Dymola. The models include the fuelling protocol (J2601) for hydrogen vehicles made by Society of Automotive Engineers (SAE) and the thermodynamic property library CoolProp is used for retrieving state point. The components in the hydrogen fuelling library are building up...

  13. Hydrogen vehicle fueling station

    Energy Technology Data Exchange (ETDEWEB)

    Daney, D.E.; Edeskuty, F.J.; Daugherty, M.A. [Los Alamos National Lab., NM (United States)] [and others

    1995-09-01

    Hydrogen fueling stations are an essential element in the practical application of hydrogen as a vehicle fuel, and a number of issues such as safety, efficiency, design, and operating procedures can only be accurately addressed by a practical demonstration. Regardless of whether the vehicle is powered by an internal combustion engine or fuel cell, or whether the vehicle has a liquid or gaseous fuel tank, the fueling station is a critical technology which is the link between the local storage facility and the vehicle. Because most merchant hydrogen delivered in the US today (and in the near future) is in liquid form due to the overall economics of production and delivery, we believe a practical refueling station should be designed to receive liquid. Systems studies confirm this assumption for stations fueling up to about 300 vehicles. Our fueling station, aimed at refueling fleet vehicles, will receive hydrogen as a liquid and dispense it as either liquid, high pressure gas, or low pressure gas. Thus, it can refuel any of the three types of tanks proposed for hydrogen-powered vehicles -- liquid, gaseous, or hydride. The paper discusses the fueling station design. Results of a numerical model of liquid hydrogen vehicle tank filling, with emphasis on no vent filling, are presented to illustrate the usefulness of the model as a design tool. Results of our vehicle performance model illustrate our thesis that it is too early to judge what the preferred method of on-board vehicle fuel storage will be in practice -- thus our decision to accommodate all three methods.

  14. Closed Loop Experiment Manager (CLEM—An Open and Inexpensive Solution for Multichannel Electrophysiological Recordings and Closed Loop Experiments

    Directory of Open Access Journals (Sweden)

    Hananel Hazan

    2017-10-01

    Full Text Available There is growing need for multichannel electrophysiological systems that record from and interact with neuronal systems in near real-time. Such systems are needed, for example, for closed loop, multichannel electrophysiological/optogenetic experimentation in vivo and in a variety of other neuronal preparations, or for developing and testing neuro-prosthetic devices, to name a few. Furthermore, there is a need for such systems to be inexpensive, reliable, user friendly, easy to set-up, open and expandable, and possess long life cycles in face of rapidly changing computing environments. Finally, they should provide powerful, yet reasonably easy to implement facilities for developing closed-loop protocols for interacting with neuronal systems. Here, we survey commercial and open source systems that address these needs to varying degrees. We then present our own solution, which we refer to as Closed Loop Experiments Manager (CLEM. CLEM is an open source, soft real-time, Microsoft Windows desktop application that is based on a single generic personal computer (PC and an inexpensive, general-purpose data acquisition board. CLEM provides a fully functional, user-friendly graphical interface, possesses facilities for recording, presenting and logging electrophysiological data from up to 64 analog channels, and facilities for controlling external devices, such as stimulators, through digital and analog interfaces. Importantly, it includes facilities for running closed-loop protocols written in any programming language that can generate dynamic link libraries (DLLs. We describe the application, its architecture and facilities. We then demonstrate, using networks of cortical neurons growing on multielectrode arrays (MEA that despite its reliance on generic hardware, its performance is appropriate for flexible, closed-loop experimentation at the neuronal network level.

  15. Space Station Habitability Research

    Science.gov (United States)

    Clearwater, Yvonne A.

    1988-01-01

    The purpose and scope of the Habitability Research Group within the Space Human Factors Office at the NASA/Ames Research Center is described. Both near-term and long-term research objectives in the space human factors program pertaining to the U.S. manned Space Station are introduced. The concept of habitability and its relevancy to the U.S. space program is defined within a historical context. The relationship of habitability research to the optimization of environmental and operational determinants of productivity is discussed. Ongoing habitability research efforts pertaining to living and working on the Space Station are described.

  16. Behavioral, neurochemical, and electrophysiological changes in an early spontaneous mouse model of nigrostriatal degeneration.

    Science.gov (United States)

    Sgadò, Paola; Viaggi, Cristina; Pinna, Annalisa; Marrone, Cristina; Vaglini, Francesca; Pontis, Silvia; Mercuri, Nicola Biagio; Morelli, Micaela; Corsini, Giovanni Umberto

    2011-08-01

    In idiopathic Parkinson's disease, clinical symptoms do not emerge until consistent neurodegeneration has occurred. The late appearance of symptoms implies the existence of a relatively long preclinical period during which several disease-induced neurochemical changes take place to mask the existence of the disease and delay its clinical manifestations. The aim of this study was to examine the neurochemical, neurophysiological, and behavioral changes induced by the loss of nigrostriatal innervation in the En1+/-;En2-/- mouse, in the 10 months following degeneration, compared to En2 null mutant mice. Behavioral analysis (Pole-test, Beam-walking test, and Inverted grid test) and field potential recordings in the striatum indicated that loss of ~70% of nigrostriatal neurons produced no significant functional effects until 8 months of age, when En1+/-;En2-/- animals started to show frank motor deficits and electrophysiological alterations in corticostriatal plasticity. Similarly, alterations in dopamine homeostasis, dopamine turnover, and dopamine innervation were observed in aged animals compared to young En1+/-;En2-/- mice. These data suggests that in En1+/-;En2-/- mice nigrostriatal degeneration in the substantia nigra is functionally compensated.

  17. Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system.

    Science.gov (United States)

    Deslandes, A C; Veiga, H; Cagy, M; Piedade, R; Pompeu, F; Ribeiro, P

    2005-07-01

    Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG) and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg) or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop) test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.

  18. Effects of caffeine on the electrophysiological, cognitive and motor responses of the central nervous system

    Directory of Open Access Journals (Sweden)

    Deslandes A.C.

    2005-01-01

    Full Text Available Caffeine is the most consumed psychoactive substance in the world. The effects of caffeine have been studied using cognitive and motor measures, quantitative electroencephalography (qEEG and event-related potentials. However, these methods are not usually employed in combination, a fact that impairs the interpretation of the results. The objective of the present study was to analyze changes in electrophysiological, cognitive and motor variables with the ingestion of caffeine, and to relate central to peripheral responses. For this purpose we recorded event-related potentials and eyes-closed, resting EEG, applied the Stroop test, and measured reaction time. Fifteen volunteers took caffeine (400 mg or placebo in a randomized, crossover, double-blind design. A significant reduction of alpha absolute power over the entire scalp and of P300 latency at the Fz electrode were observed after caffeine ingestion. These results are consistent with a stimulatory effect of caffeine, although there was no change in the attention (Stroop test or in reaction time. The qEEG seems to be the most sensitive index of the changes produced by caffeine in the central nervous system since it proved to be capable of detecting changes that were not evident in the tests of cognitive or motor performance.

  19. Effect of the small-world structure on encoding performance in the primary visual cortex: an electrophysiological and modeling analysis.

    Science.gov (United States)

    Shi, Li; Niu, Xiaoke; Wan, Hong

    2015-05-01

    The biological networks have been widely reported to present small-world properties. However, the effects of small-world network structure on population's encoding performance remain poorly understood. To address this issue, we applied a small world-based framework to quantify and analyze the response dynamics of cell assemblies recorded from rat primary visual cortex, and further established a population encoding model based on small world-based generalized linear model (SW-GLM). The electrophysiological experimental results show that the small world-based population responses to different topological shapes present significant variation (t test, p 0.8), while no significant variation was found for control networks without considering their spatial connectivity (t test, p > 0.05; effect size: Hedge's g < 0.5). Furthermore, the numerical experimental results show that the predicted response under SW-GLM is more accurate and reliable compared to the control model without small-world structure, and the decoding performance is also improved about 10 % by taking the small-world structure into account. The above results suggest the important role of the small-world neural structure in encoding visual information for the neural population by providing electrophysiological and theoretical evidence, respectively. The study helps greatly to well understand the population encoding mechanisms of visual cortex.

  20. Power station instrumentation

    International Nuclear Information System (INIS)

    Jervis, M.W.

    1993-01-01

    Power stations are characterized by a wide variety of mechanical and electrical plant operating with structures, liquids and gases working at high pressures and temperatures and with large mass flows. The voltages and currents are also the highest that occur in most industries. In order to achieve maximum economy, the plant is operated with relatively small margins from conditions that can cause rapid plant damage, safety implications, and very high financial penalties. In common with other process industries, power stations depend heavily on control and instrumentation. These systems have become particularly significant, in the cost-conscious privatized environment, for providing the means to implement the automation implicit in maintaining safety standards, improving generation efficiency and reducing operating manpower costs. This book is for professional instrumentation engineers who need to known about their use in power stations and power station engineers requiring information about the principles and choice of instrumentation available. There are 8 chapters; chapter 4 on instrumentation for nuclear steam supply systems is indexed separately. (Author)

  1. Shippingport Station Decommissioning Project

    International Nuclear Information System (INIS)

    1989-01-01

    This Topical Report is a synopsis of the decontamination of plant components and structures at the Shippingport Station Decommissioning Project (SSDP). The information is provided as a part of the Technology Transfer Program to document the preparation activities in support of the shipment of radioactive wastes and the unconditional release of the site and structural materials. 1 ref., 16 figs., 4 tabs

  2. Galileo Station Keeping Strategy

    Science.gov (United States)

    Perez-Cambriles, Antonio; Bejar-Romero, Juan Antonio; Aguilar-Taboada, Daniel; Perez-Lopez, Fernando; Navarro, Daniel

    2007-01-01

    This paper presents analyses done for the design and implementation of the Maneuver Planning software of the Galileo Flight Dynamics Facility. The station keeping requirements of the constellation have been analyzed in order to identify the key parameters to be taken into account in the design and implementation of the software.

  3. Designing a Weather Station

    Science.gov (United States)

    Roman, Harry T.

    2012-01-01

    The collection and analysis of weather data is crucial to the location of alternate energy systems like solar and wind. This article presents a design challenge that gives students a chance to design a weather station to collect data in advance of a large wind turbine installation. Data analysis is a crucial part of any science or engineering…

  4. Avoiding Service Station Fraud.

    Science.gov (United States)

    Burton, Grace M.; Burton, John R.

    1982-01-01

    High school students are warned against service station fraud. A problem-solving section is designed to help students calculate consumer costs for various fraudulent transactions. Several ways of reducing fraud or of lessening the chances of problems are noted. (MP)

  5. The Service Station.

    Science.gov (United States)

    Ohio State Univ., Columbus. Center for Vocational and Technical Education.

    The purpose of the teacher's guide is to encourage the primary student to expand his or her awareness of jobs within the community. The role of the service station worker is examined, with emphasis on the goods and services provided. Subject areas for which the materials in this guide have potential are social studies, art, and language. Each set…

  6. Electrostatic pickup station

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    Electrostatic pickup station, with 4 electrodes, to measure beam position in the horizontal and vertical plane. This type is used in the transfer lines leaving the PS (TT2, TTL2, TT70). See also 8206063, where the electrode shapes are clearly visible.

  7. Point Lepreau generating station

    International Nuclear Information System (INIS)

    Ganong, G.H.D.; Strang, A.E.; Gunter, G.E.; Thompson, T.S.

    Point Lepreau-1 reactor is a 600 MWe generating station expected to be in service by October 1979. New Brunswick is suffering a 'catch up' phenomenon in load growth and needs to decrease dependence on foreign oil. The site is on salt water and extensive study has gone into corrosion control. Project management, financing and scheduling have unique aspects. (E.C.B.)

  8. Mojave Base Station Implementation

    Science.gov (United States)

    Koscielski, C. G.

    1984-01-01

    A 12.2 meter diameter X-Y mount antenna was reconditioned for use by the crustal dynamic project as a fixed base station. System capabilities and characteristics and key performance parameters for subsystems are presented. The implementation is completed.

  9. Electrophysiological and pathological study of focal cortical dysplasia

    International Nuclear Information System (INIS)

    Hodozuka, Akira; Hashizume, Kiyotaka; Hayashi, Yoshimitsu; Tanaka, Tatsuya

    2008-01-01

    Clinical and experimental studies on focal cortical dysplasia (FCD) were carried out. For the experimental study, an experimental FCD model of rats was developed. Twenty Wistar rats at 0-2 days after birth were used for the study. Kainic acid (KA) solution was injected stereotaxically into medial and lateral sites of the sensori-motor cortex. Bipolar electrodes were inserted. The behavior of the rats and electroencephalography (EEG) were recorded using a digital video-EEG monitoring system. After observation periods of 1, 2 and 6 months, the rats were perfused for pathological study. FCD was observed adjacent to the site of KA injection in all rats more than one month after the injection. EEG recording demonstrated focal spike discharges in and around the site of injection. However, clinical seizure was not observed. Pathological studies showed decrease in gamma aminobutyric acid (GABA)-A receptors and increase in GABA-B receptors not only in the lesion but also in perilesional areas. Fifteen surgical cases of FCD with intractable epilepsy were included in the clinical study. Neuro-imaging studies including high-resolution MRI and single photon emission computed tomography (SPECT) were performed. Conventional EEG studies demonstrated focal EEG abnormalities with epileptic phenomena. At surgery, intraoperative electrocorticography (ECoG) was performed in order to localize epileptic foci under neuroleptanalgesia. Fourteen patients showed epileptiform discharges on preresection ECoG. All foci in non-eloquent areas were resected. Pathological studies including immunohistochemical staining were performed, and characteristics of the FCD in relation to EEG findings were analyzed. Electrophysiological examination revealed epileptogenecity not only in the lesions but also in perilesional areas. In the lesions, immunohistochemical studies showed decrease in GABA-A receptors and increase in GABA-B receptors in both the lesions and perilesional areas, but N

  10. Space station operating system study

    Science.gov (United States)

    Horn, Albert E.; Harwell, Morris C.

    1988-01-01

    The current phase of the Space Station Operating System study is based on the analysis, evaluation, and comparison of the operating systems implemented on the computer systems and workstations in the software development laboratory. Primary emphasis has been placed on the DEC MicroVMS operating system as implemented on the MicroVax II computer, with comparative analysis of the SUN UNIX system on the SUN 3/260 workstation computer, and to a limited extent, the IBM PC/AT microcomputer running PC-DOS. Some benchmark development and testing was also done for the Motorola MC68010 (VM03 system) before the system was taken from the laboratory. These systems were studied with the objective of determining their capability to support Space Station software development requirements, specifically for multi-tasking and real-time applications. The methodology utilized consisted of development, execution, and analysis of benchmark programs and test software, and the experimentation and analysis of specific features of the system or compilers in the study.

  11. Retinal Electrophysiology Is a Viable Preclinical Biomarker for Drug Penetrance into the Central Nervous System

    Directory of Open Access Journals (Sweden)

    Jason Charng

    2016-01-01

    Full Text Available Objective. To examine whether retinal electrophysiology is a useful surrogate marker of drug penetrance into the central nervous system (CNS. Materials and Methods. Brain and retinal electrophysiology were assessed with full-field visually evoked potentials and electroretinograms in conscious and anaesthetised rats following systemic or local administrations of centrally penetrant (muscimol or nonpenetrant (isoguvacine compounds. Results. Local injections into the eye/brain bypassed the blood neural barriers and produced changes in retinal/brain responses for both drugs. In conscious animals, systemic administration of muscimol resulted in retinal and brain biopotential changes, whereas systemic delivery of isoguvacine did not. General anaesthesia confounded these outcomes. Conclusions. Retinal electrophysiology, when recorded in conscious animals, shows promise as a viable biomarker of drug penetration into the CNS. In contrast, when conducted under anaesthetised conditions confounds can be induced in both cortical and retinal electrophysiological recordings.

  12. Two subgroups of antipsychotic-naive, first-episode schizophrenia patients identified with a Gaussian mixture model on cognition and electrophysiology

    DEFF Research Database (Denmark)

    Bak, N.; Ebdrup, B.H.; Oranje, B

    2017-01-01

    Deficits in information processing and cognition are among the most robust findings in schizophrenia patients. Previous efforts to translate group-level deficits into clinically relevant and individualized information have, however, been non-successful, which is possibly explained by biologically...... and sixty-five healthy controls underwent extensive electrophysiological and neurocognitive test batteries. Patients were assessed on the Positive and Negative Syndrome Scale (PANSS) before and after 6 weeks of monotherapy with the relatively selective D2 receptor antagonist, amisulpride (280.3±159 mg per...... day). A reduced principal component space based on 19 electrophysiological variables and 26 cognitive variables was used as input for a Gaussian mixture model to identify subgroups of patients. With support vector machines, we explored the relation between PANSS subscores and the identified subgroups...

  13. Space Station Freedom - Accommodation for technology R&D

    Science.gov (United States)

    Holt, Alan C.

    1989-01-01

    The paper examines the features of the accommodation equipment designed for the candidate technology payloads of the Space Station, which include magnetic plasma thruster systems and a hypothetical advanced electromagnetic propulsion system utilizing high-temperature superconductivity materials. The review of the accommodation-equipment concepts supports the assumption that some propulsion technologies can be tested on the Space Station while being attached externally to the station's truss structure. For testing technologies with inherent operation or performance hazards, space platforms and smaller free-flyers coordinated with the Space Station can be used. Diagrams illustrating typical accommodation equipment configurations are included.

  14. The influence of object and background color manipulations on the electrophysiological indices of recognition memory.

    Science.gov (United States)

    Ecker, Ullrich K H; Zimmer, Hubert D; Groh-Bordin, Christian

    2007-12-14

    In a recognition memory experiment, the claim was tested that intrinsic object features contribute to familiarity, whereas extrinsic context features do not. We used the study-test manipulation of color to investigate the perceptual specificity of ERP old-new effects associated with familiarity and recollection. Color was either an intrinsic surface feature of the object or a feature of the surrounding context (a frame encasing the object); thus, the same feature was manipulated across intrinsic/extrinsic conditions. Subjects performed a threefold (same color/different color/new object) decision, making feature information task-relevant. Results suggest that the intrinsic manipulation of color affected the mid-frontal old-new effect associated with familiarity, while this effect was not influenced by extrinsic manipulation. This ERP pattern could not be explained by basic behavioral performance differences. It is concluded that familiarity can be perceptually specific with regard to intrinsic information belonging to the object. The putative electrophysiological signature of recollection - a late parietal old-new effect - was not present in the data, and reasons for this null effect are discussed.

  15. A comparison of electrophysiologically determined spectral responses in six subspecies of Lymantria.

    Science.gov (United States)

    Crook, Damon J; Hull-Sanders, Helen M; Hibbard, Emily L; Mastro, Victor C

    2014-04-01

    The spectral sensitivity of the compound eye in three gypsy moth species from six different geographical regions (Lymantria dispar asiatica Vnukovskij [Asian gypsy moth], Lymantria dispar japonica Motschulsky [Japanese gypsy moth], and Lymantria dispar dispar L. [North American gypsy moth]) was tested electrophysiologically in the wavelength region 300-700 nm. For all moths examined, a maximum response occurred in the 480-520-nm range (blue-green region) with a shoulder peak occurring at 460 nm. A smaller, secondary peak was observed for both sexes at the 340-380-nm range, which is in the region considered behaviorally maximal in night-flying insects. No peaks in sensitivity were observed between 520 and 700 nm (red region) for any of the moths tested. Based on our retinal recording data, a short wavelength blocking filter with a transition wavelength near 500 nm should reduce gypsy moth attraction to artificial lighting sources. This would help reduce the number of Lymantria-infested ships traveling to and from foreign ports.

  16. Language specificity of lexical-phonological therapy in bilingual aphasia: A clinical and electrophysiological study.

    Science.gov (United States)

    Radman, Narges; Spierer, Lucas; Laganaro, Marina; Annoni, Jean-Marie; Colombo, Françoise

    2016-08-01

    Based on findings for overlapping representations of bilingual people's first (L1) and second (L2) languages, unilingual therapies of bilingual aphasia have been proposed to benefit the untrained language. However, the generalisation patterns of intra- and cross-language and phonological therapy and their neural bases remain unclear. We tested whether the effects of an intensive lexical-phonological training (LPT) in L2 transferred to L1 word production in a Persian-French bilingual stroke patient with Broca's aphasia. Language performance was assessed using the Bilingual Aphasia Test, a 144-item picture naming (PN) task and a word-picture verification (WPV) task. Electroencephalography (EEG) was recorded during PN and WPV in both languages before and after an LPT in French on a wordlist from the PN task. After the therapy, naming improved only for the treated L2 items. The naming performance improved neither in the untrained L2 items nor in the corresponding items in L1. EEG analyses revealed a Language x Session topographic interaction at 540 ms post-stimulus, driven by a modification of the electrophysiological response to the treated L2 but not L1 items. These results indicate that LPT modified the brain networks engaged in the phonological-phonetic processing during naming only in the trained language for the trained items.

  17. Operation feedback of hydrogen filling station

    International Nuclear Information System (INIS)

    Pregassame, S.; Barral, K.; Allidieres, L.; Charbonneau, T.; Lacombe, Y.

    2004-01-01

    One of the technical challenges of hydrogen technology is the development of hydrogen infrastructures which satisfy either safety requirements and reliability of filling processes. AIR LIQUIDE realized an hydrogen filling station in Sassenage (France) operational since September 2003. This station is able to fill 3 buses a day up to 350bar by equilibrium with high pressure buffers. In parallel with commercial stations, the group wanted to create a testing ground in real conditions running with several objectives: validate on a full scale bench a simulation tool able to predict the temperature of both gas and cylinder's materials during filling processes; define the best filling procedures in order to reach mass, temperature and filling time targets; analyse the temperature distribution and evolution inside the cylinder; get a general knowledge about hydrogen stations from safety and reliability point of view; operate the first full scale refuelling station in France. The station is also up-graded for 700bar filling from either a liquid hydrogen source or a gas booster, with cold filling possibility. This paper presents the results concerning 350bar filling : thermal effects, optimal filling procedures and influence of parameters such as climatic conditions are discussed. (author)

  18. Hydrogen Filling Station

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, Robert F; Sabacky, Bruce; Anderson II, Everett B; Haberman, David; Al-Hassin, Mowafak; He, Xiaoming; Morriseau, Brian

    2010-02-24

    Hydrogen is an environmentally attractive transportation fuel that has the potential to displace fossil fuels. The Freedom CAR and Freedom FUEL initiatives emphasize the importance of hydrogen as a future transportation fuel. Presently, Las Vegas has one hydrogen fueling station powered by natural gas. However, the use of traditional sources of energy to produce hydrogen does not maximize the benefit. The hydrogen fueling station developed under this grant used electrolysis units and solar energy to produce hydrogen fuel. Water and electricity are furnished to the unit and the output is hydrogen and oxygen. Three vehicles were converted to utilize the hydrogen produced at the station. The vehicles were all equipped with different types of technologies. The vehicles were used in the day-to-day operation of the Las Vegas Valley Water District and monitoring was performed on efficiency, reliability and maintenance requirements. The research and demonstration utilized for the reconfiguration of these vehicles could lead to new technologies in vehicle development that could make hydrogen-fueled vehicles more cost effective, economical, efficient and more widely used. In order to advance the development of a hydrogen future in Southern Nevada, project partners recognized a need to bring various entities involved in hydrogen development and deployment together as a means of sharing knowledge and eliminating duplication of efforts. A road-mapping session was held in Las Vegas in June 2006. The Nevada State Energy Office, representatives from DOE, DOE contractors and LANL, NETL, NREL were present. Leadership from the National hydrogen Association Board of Directors also attended. As a result of this session, a roadmap for hydrogen development was created. This roadmap has the ability to become a tool for use by other road-mapping efforts in the hydrogen community. It could also become a standard template for other states or even countries to approach planning for a hydrogen

  19. An open-source hardware and software system for acquisition and real-time processing of electrophysiology during high field MRI.

    Science.gov (United States)

    Purdon, Patrick L; Millan, Hernan; Fuller, Peter L; Bonmassar, Giorgio

    2008-11-15

    Simultaneous recording of electrophysiology and functional magnetic resonance imaging (fMRI) is a technique of growing importance in neuroscience. Rapidly evolving clinical and scientific requirements have created a need for hardware and software that can be customized for specific applications. Hardware may require customization to enable a variety of recording types (e.g., electroencephalogram, local field potentials, or multi-unit activity) while meeting the stringent and costly requirements of MRI safety and compatibility. Real-time signal processing tools are an enabling technology for studies of learning, attention, sleep, epilepsy, neurofeedback, and neuropharmacology, yet real-time signal processing tools are difficult to develop. We describe an open-source system for simultaneous electrophysiology and fMRI featuring low-noise (tested up to 7T), and user-programmable real-time signal processing. The hardware distribution provides the complete specifications required to build an MRI-compatible electrophysiological data acquisition system, including circuit schematics, print circuit board (PCB) layouts, Gerber files for PCB fabrication and robotic assembly, a bill of materials with part numbers, data sheets, and vendor information, and test procedures. The software facilitates rapid implementation of real-time signal processing algorithms. This system has been used in human EEG/fMRI studies at 3 and 7T examining the auditory system, visual system, sleep physiology, and anesthesia, as well as in intracranial electrophysiological studies of the non-human primate visual system during 3T fMRI, and in human hyperbaric physiology studies at depths of up to 300 feet below sea level.

  20. Multiplexed, high density electrophysiology with nanofabricated neural probes.

    Directory of Open Access Journals (Sweden)

    Jiangang Du

    Full Text Available Extracellular electrode arrays can reveal the neuronal network correlates of behavior with single-cell, single-spike, and sub-millisecond resolution. However, implantable electrodes are inherently invasive, and efforts to scale up the number and density of recording sites must compromise on device size in order to connect the electrodes. Here, we report on silicon-based neural probes employing nanofabricated, high-density electrical leads. Furthermore, we address the challenge of reading out multichannel data with an application-specific integrated circuit (ASIC performing signal amplification, band-pass filtering, and multiplexing functions. We demonstrate high spatial resolution extracellular measurements with a fully integrated, low noise 64-channel system weighing just 330 mg. The on-chip multiplexers make possible recordings with substantially fewer external wires than the number of input channels. By combining nanofabricated probes with ASICs we have implemented a system for performing large-scale, high-density electrophysiology in small, freely behaving animals that is both minimally invasive and highly scalable.

  1. Electrophysiological changes in rats after modulated microwave irradiation

    International Nuclear Information System (INIS)

    Szabo, L.D.; Thuroczy, G.; Kubinyi, G.; Bakos, J.

    1992-01-01

    The effects of modulated microwave irradiation on the electrophysiological changes in rats were studied. The response of the central nervous system (CNS) was observed simultaneously to the cardiovascular system by using quantitative polygraphic measuring system. In acute experiments on rat the electroencephalogram (EEG), rheoencephalogram (REG) as an index of cerebral blood flow (CBF), brain tissue DC impedance and temperature, ECG were recorded in parallel before, during and after exposure of the brain localized amplitude (AM) modulated (16 Hz) and continuous wave (CW) microwave exposure. The average specific absorption rates (SAR) in the brain were 8.4 mW/g, 16.8 mW/g and 42 mW/g (CW) respectively. At thermal level CW exposure the delta band of EEG increased. In case of low intensities modulated exposure the beta band of EEG spectrum increased. No changes were observed during athermal CW irradiation on the EEG. Moderate modulation depended changes were measured in cerebral metabolism, cerebral blood flow and cardiorespiratoric system during microwave irradiation. (author)

  2. Logo Effects on Brand Extension Evaluations from the Electrophysiological Perspective.

    Science.gov (United States)

    Shang, Qian; Pei, Guanxiong; Dai, Shenyi; Wang, Xiaoyi

    2017-01-01

    Brand extension typically has two strategies: brand name extension (BN) and brand logo extension (BL). The current study explored which strategy (BN or BL) better enhanced the success of dissimilar brand extension and product promotion in enterprises. Event-related potentials (ERPs) were used to investigate electrophysiological processes when subjects evaluated their acceptance of the brand extension using a combined picture of S1 and S2. S1 was a famous brand presented by two identity signs (brand name and brand logo). S2 was a picture of an extension product that belonged to a dissimilar product category than S1. The behavior data showed that BL was more acceptable than BN in the dissimilar brand extension. The neurophysiology process was reflected by a less negative N2 component and a larger P300 component in the BL than in the BN. We suggested that N2 reflected a whole conflict between the brand-product combination and the long-term memory and that P300 could be regarded as the reflection of the categorization process in the working memory.

  3. Audiological and electrophysiological assessment of professional pop/rock musicians.

    Science.gov (United States)

    Samelli, Alessandra G; Matas, Carla G; Carvallo, Renata M M; Gomes, Raquel F; de Beija, Carolina S; Magliaro, Fernanda C L; Rabelo, Camila M

    2012-01-01

    In the present study, we evaluated peripheral and central auditory pathways in professional musicians (with and without hearing loss) compared to non-musicians. The goal was to verify if music exposure could affect auditory pathways as a whole. This is a prospective study that compared the results obtained between three groups (musicians with and without hearing loss and non-musicians). Thirty-two male individuals participated and they were assessed by: Immittance measurements, pure-tone air conduction thresholds at all frequencies from 0.25 to 20 kHz, Transient Evoked Otoacoustic Emissions, Auditory Brainstem Response (ABR), and Cognitive Potential. The musicians showed worse hearing thresholds in both conventional and high frequency audiometry when compared to the non-musicians; the mean amplitude of Transient Evoked Otoacoustic Emissions was smaller in the musicians group, but the mean latencies of Auditory Brainstem Response and Cognitive Potential were diminished in the musicians when compared to the non-musicians. Our findings suggest that the population of musicians is at risk for developing music-induced hearing loss. However, the electrophysiological evaluation showed that latency waves of ABR and P300 were diminished in musicians, which may suggest that the auditory training to which these musicians are exposed acts as a facilitator of the acoustic signal transmission to the cortex.

  4. Audiological and electrophysiological assessment of professional pop/rock musicians

    Directory of Open Access Journals (Sweden)

    Alessandra G Samelli

    2012-01-01

    Full Text Available In the present study, we evaluated peripheral and central auditory pathways in professional musicians (with and without hearing loss compared to non-musicians. The goal was to verify if music exposure could affect auditory pathways as a whole. This is a prospective study that compared the results obtained between three groups (musicians with and without hearing loss and non-musicians. Thirty-two male individuals participated and they were assessed by: Immittance measurements, pure-tone air conduction thresholds at all frequencies from 0.25 to 20 kHz, Transient Evoked Otoacoustic Emissions, Auditory Brainstem Response (ABR, and Cognitive Potential. The musicians showed worse hearing thresholds in both conventional and high frequency audiometry when compared to the non-musicians; the mean amplitude of Transient Evoked Otoacoustic Emissions was smaller in the musicians group, but the mean latencies of Auditory Brainstem Response and Cognitive Potential were diminished in the musicians when compared to the non-musicians. Our findings suggest that the population of musicians is at risk for developing music-induced hearing loss. However, the electrophysiological evaluation showed that latency waves of ABR and P300 were diminished in musicians, which may suggest that the auditory training to which these musicians are exposed acts as a facilitator of the acoustic signal transmission to the cortex.

  5. Visual search elicits the electrophysiological marker of visual working memory.

    Directory of Open Access Journals (Sweden)

    Stephen M Emrich

    Full Text Available BACKGROUND: Although limited in capacity, visual working memory (VWM plays an important role in many aspects of visually-guided behavior. Recent experiments have demonstrated an electrophysiological marker of VWM encoding and maintenance, the contralateral delay activity (CDA, which has been shown in multiple tasks that have both explicit and implicit memory demands. Here, we investigate whether the CDA is evident during visual search, a thoroughly-researched task that is a hallmark of visual attention but has no explicit memory requirements. METHODOLOGY/PRINCIPAL FINDINGS: The results demonstrate that the CDA is present during a lateralized search task, and that it is similar in amplitude to the CDA observed in a change-detection task, but peaks slightly later. The changes in CDA amplitude during search were strongly correlated with VWM capacity, as well as with search efficiency. These results were paralleled by behavioral findings showing a strong correlation between VWM capacity and search efficiency. CONCLUSIONS/SIGNIFICANCE: We conclude that the activity observed during visual search was generated by the same neural resources that subserve VWM, and that this activity reflects the maintenance of previously searched distractors.

  6. Groin hematoma after electrophysiological procedures-incidence and predisposing factors.

    Science.gov (United States)

    Dalsgaard, Anja Borgen; Jakobsen, Christina Spåbæk; Riahi, Sam; Hjortshøj, Søren

    2014-10-01

    We evaluated the incidence and predisposing factors of groin hematomas after electrophysiological (EP) procedures. Prospective, observational study, enrolling consecutive patients after EP procedures (Atrial fibrillation: n = 151; Supraventricular tachycardia/Diagnostic EP: n = 82; Ventricular tachycardia: n = 18). Patients underwent manual compression for 10 min and 3 h post procedural bed rest. AF ablations were performed with INR 2-3, ACT > 300, and no protamine sulfate. Adhesive pressure dressings (APDs) were used if sheath size ≥ 10F; procedural time > 120 min; and BMI > 30. Patient-reported hematomas were recorded by a telephone follow-up after 2 weeks. Hematoma developed immediately in 26 patients (10%) and after 14 days significant hematoma was reported in 68 patients (27%). Regression analysis on sex, age, BMI 25, ACT 300, use of APD, sheath size and number, and complicated venous access was not associated with hematoma, either immediately after the procedure or after 14 days. Any hematoma presenting immediately after procedures was associated with patient-reported hematomas after 14 days, odds ratio 18.7 (CI 95%: 5.00-69.8; P hematoma immediately after EP procedures was the sole predictor of patient-reported hematoma after 2 weeks. Initiatives to prevent groin hematoma should focus on the procedure itself as well as post-procedural care.

  7. Electrophysiological measurement of interest during walking in a simulated environment.

    Science.gov (United States)

    Takeda, Yuji; Okuma, Takashi; Kimura, Motohiro; Kurata, Takeshi; Takenaka, Takeshi; Iwaki, Sunao

    2014-09-01

    A reliable neuroscientific technique for objectively estimating the degree of interest in a real environment is currently required in the research fields of neuroergonomics and neuroeconomics. Toward the development of such a technique, the present study explored electrophysiological measures that reflect an observer's interest in a nearly-real visual environment. Participants were asked to walk through a simulated shopping mall and the attractiveness of the shopping mall was manipulated by opening and closing the shutters of stores. During the walking task, participants were exposed to task-irrelevant auditory probes (two-stimulus oddball sequence). The results showed a smaller P2/early P3a component of task-irrelevant auditory event-related potentials and a larger lambda response of eye-fixation-related potentials in an interesting environment (i.e., open-shutter condition) than in a boring environment (i.e., closed-shutter condition); these findings can be reasonably explained by supposing that participants allocated more attentional resources to visual information in an interesting environment than in a boring environment, and thus residual attentional resources that could be allocated to task-irrelevant auditory probes were reduced. The P2/early P3a component and the lambda response may be useful measures of interest in a real visual environment. Copyright © 2014 Elsevier B.V. All rights reserved.

  8. Electrophysiological CNS-processes related to associative learning in humans.

    Science.gov (United States)

    Christoffersen, Gert R J; Schachtman, Todd R

    2016-01-01

    The neurophysiology of human associative memory has been studied with electroencephalographic techniques since the 1930s. This research has revealed that different types of electrophysiological processes in the human brain can be modified by conditioning: sensory evoked potentials, sensory induced gamma-band activity, periods of frequency-specific waves (alpha and beta waves, the sensorimotor rhythm and the mu-rhythm) and slow cortical potentials. Conditioning of these processes has been studied in experiments that either use operant conditioning or repeated contingent pairings of conditioned and unconditioned stimuli (classical conditioning). In operant conditioning, the appearance of a specific brain process is paired with an external stimulus (neurofeedback) and the feedback enables subjects to obtain varying degrees of control of the CNS-process. Such acquired self-regulation of brain activity has found practical uses for instance in the amelioration of epileptic seizures, Autism Spectrum Disorders (ASD) and Attention Deficit Hyperactivity Disorder (ADHD). It has also provided communicative means of assistance for tetraplegic patients through the use of brain computer interfaces. Both extra and intracortically recorded signals have been coupled with contingent external feedback. It is the aim for this review to summarize essential results on all types of electromagnetic brain processes that have been modified by classical or operant conditioning. The results are organized according to type of conditioned EEG-process, type of conditioning, and sensory modalities of the conditioning stimuli. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Mobile environmental radiation monitoring station

    International Nuclear Information System (INIS)

    Assido, H.; Shemesh, Y.; Mazor, T.; Tal, N.; Barak, D.

    1997-01-01

    A mobile environmental radiation monitoring station has been developed and established for the Israeli Ministry of Environment. The radiation monitoring station is ready for immediate placing in any required location, or can be operated from a vehicle. The station collects data Tom the detector and transfers it via cellular communication network to a Computerized Control Center for data storage, processing, and display . The mobile station is fully controlled from the. Routinely, the mobile station responses to the data request accumulated since the last communication session. In case of fault or alarm condition in the mobile station, a local claim is activated and immediately initiates communication with the via cellular communication network. (authors)

  10. In vivo characterization of the electrophysiological and astrocytic responses to a silicon neuroprobe implanted in the mouse neocortex.

    Science.gov (United States)

    Mols, Katrien; Musa, Silke; Nuttin, Bart; Lagae, Liesbet; Bonin, Vincent

    2017-11-15

    Silicon neuroprobes hold great potential for studies of large-scale neural activity and brain computer interfaces, but data on brain response in chronic implants is limited. Here we explored with in vivo cellular imaging the response to multisite silicon probes for neural recordings. We tested a chronic implant for mice consisting of a CMOS-compatible silicon probe rigidly implanted in the cortex under a cranial imaging window. Multiunit recordings of cortical neurons with the implant showed no degradation of electrophysiological signals weeks after implantation (mean spike and noise amplitudes of 186 ± 42 µV pp and 16 ± 3.2 µV rms , respectively, n = 5 mice). Two-photon imaging through the cranial window allowed longitudinal monitoring of fluorescently-labeled astrocytes from the second week post implantation for 8 weeks (n = 3 mice). The imaging showed a local increase in astrocyte-related fluorescence that remained stable from the second to the tenth week post implantation. These results demonstrate that, in a standard electrophysiology protocol in mice, rigidly implanted silicon probes can provide good short to medium term chronic recording performance with a limited astrocyte inflammatory response. The precise factors influencing the response to silicon probe implants remain to be elucidated.

  11. Test

    DEFF Research Database (Denmark)

    Bendixen, Carsten

    2014-01-01

    Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers.......Bidrag med en kortfattet, introducerende, perspektiverende og begrebsafklarende fremstilling af begrebet test i det pædagogiske univers....

  12. Battery charging stations

    Energy Technology Data Exchange (ETDEWEB)

    Bergey, M.

    1997-12-01

    This paper discusses the concept of battery charging stations (BCSs), designed to service rural owners of battery power sources. Many such power sources now are transported to urban areas for recharging. A BCS provides the opportunity to locate these facilities closer to the user, is often powered by renewable sources, or hybrid systems, takes advantage of economies of scale, and has the potential to provide lower cost of service, better service, and better cost recovery than other rural electrification programs. Typical systems discussed can service 200 to 1200 people, and consist of stations powered by photovoltaics, wind/PV, wind/diesel, or diesel only. Examples of installed systems are presented, followed by cost figures, economic analysis, and typical system design and performance numbers.

  13. The nuclear power station

    International Nuclear Information System (INIS)

    Plettner, B.

    1987-04-01

    The processes taking place in a nuclear power plant and the dangers arising from a nuclear power station are described. The means and methods of controlling, monitoring, and protecting the plant and things that can go wrong are presented. There is also a short discourse on the research carried out in the USA and Germany, aimed at assessing the risks of utilising nuclear energy by means of the incident tree analysis and probability calculations. (DG) [de

  14. International Space Station exhibit

    Science.gov (United States)

    2000-01-01

    The International Space Station (ISS) exhibit in StenniSphere at John C. Stennis Space Center in Hancock County, Miss., gives visitors an up-close look at the largest international peacetime project in history. Step inside a module of the ISS and glimpse how astronauts will live and work in space. Currently, 16 countries contribute resources and hardware to the ISS. When complete, the orbiting research facility will be larger than a football field.

  15. Shippingport station communications program

    International Nuclear Information System (INIS)

    Stote, J.J.

    1988-01-01

    The author discusses how the communications program for the Shippingport Atomic Power Station has a long history. It can be traced as far back as 1953, when the U.S. Atomic Energy Commission (AEC) awarded a contract to Westinghouse Electric to design the nuclear portion of a power plant for electric utility use. During May of the next year, President Eisenhower initiated groundbreaking ceremonies for the construction of the commercial atomic power plant at Shippingport, Pennsylvania

  16. Multiscale electrophysiology format: an open-source electrophysiology format using data compression, encryption, and cyclic redundancy check.

    Science.gov (United States)

    Brinkmann, Benjamin H; Bower, Mark R; Stengel, Keith A; Worrell, Gregory A; Stead, Matt

    2009-01-01

    Continuous, long-term (up to 10 days) electrophysiological monitoring using hybrid intracranial electrodes is an emerging tool for presurgical epilepsy evaluation and fundamental investigations of seizure generation. Detection of high-frequency oscillations and microseizures could provide valuable insights into causes and therapies for the treatment of epilepsy, but requires high spatial and temporal resolution. Our group is currently using hybrid arrays composed of up to 320 micro- and clinical macroelectrode arrays sampled at 32 kHz per channel with 18-bits of A/D resolution. Such recordings produce approximately 3 terabytes of data per day. Existing file formats have limited data compression capabilities, and do not offer mechanisms for protecting patient identifying information or detecting data corruption during transmission or storage. We present a novel file format that employs range encoding to provide a high degree of data compression, a three-tiered 128-bit encryption system for patient information and data security, and a 32-bit cyclic redundancy check to verify the integrity of compressed data blocks. Open-source software to read, write, and process these files are provided.

  17. Emergency Medical Service (EMS) Stations

    Data.gov (United States)

    Kansas Data Access and Support Center — EMS Locations in Kansas The EMS stations dataset consists of any location where emergency medical services (EMS) personnel are stationed or based out of, or where...

  18. Weigh-in-Motion Stations

    Data.gov (United States)

    Department of Homeland Security — The data included in the GIS Traffic Stations Version database have been assimilated from station description files provided by FHWA for Weigh-in-Motion (WIM), and...

  19. Automatic Traffic Recorder (ATR) Stations

    Data.gov (United States)

    Department of Homeland Security — The data included in the GIS Traffic Stations Version database have been assimilated from station description files provided by FHWA for Weigh-in-Motion (WIM), and...

  20. Emotional Availability Modulates Electrophysiological Correlates of Executive Functions in Preschool Children.

    Science.gov (United States)

    Schneider-Hassloff, Henriette; Zwönitzer, Annabel; Künster, Anne K; Mayer, Carmen; Ziegenhain, Ute; Kiefer, Markus

    2016-01-01

    Executive functions (EFs) - a set of cognitive control abilities - mediate resilience to stress and are associated with academic achievement and health throughout life. They are crucially linked to prefrontal cortex function as well as to other cortical and subcortical brain functions, which are maturing throughout childhood at different rates. Recent behavioral research suggested that children's EFs were related to parenting quality and child attachment security, but the neural correlates of these associations are unknown. With this study we tested in 4- to 6-year-old healthy children (N = 27) how emotional availability (EA) of the mother-child-interaction was associated with behavioral and electrophysiological correlates of response inhibition (a core EF) in a Go/Nogo task, using event-related potential recordings (ERPs), and with behavioral performance in a Delay of Gratification (DoG) and a Head-Toes-Knees-Shoulders task (HTKS). Our data showed that the Go/Nogo task modulated children's ERP components resembling adult electrophysiological indices of response inhibition - the N2 and P3/LPC ERPs-, but the children's N2 and P3/LPC ERPs showed longer latencies. Higher maternal autonomy-fostering behavior and greater child responsiveness were significantly associated with smaller children's N2 Go/Nogo effects at fronto-central and parietal sites and with greater Go/Nogo effects in the N2 time window at occipital sites, over and above children's age and intelligence. Additionally, greater maternal sensitivity and a higher dyadic EA quality of the mother-child-interaction went along with greater occipital Go/Nogo effects in the N2 time window, but this effect clearly diminished when we controlled for children's age and intelligence. Higher maternal autonomy-support was also positively associated with better HTKS performance, and higher dyadic EA quality went along with higher HTKS and DoG scores. However, no significant associations were found between EA variables and