WorldWideScience

Sample records for electronic design automation

  1. Automated electronic filter design

    CERN Document Server

    Banerjee, Amal

    2017-01-01

    This book describes a novel, efficient and powerful scheme for designing and evaluating the performance characteristics of any electronic filter designed with predefined specifications. The author explains techniques that enable readers to eliminate complicated manual, and thus error-prone and time-consuming, steps of traditional design techniques. The presentation includes demonstration of efficient automation, using an ANSI C language program, which accepts any filter design specification (e.g. Chebyschev low-pass filter, cut-off frequency, pass-band ripple etc.) as input and generates as output a SPICE(Simulation Program with Integrated Circuit Emphasis) format netlist. Readers then can use this netlist to run simulations with any version of the popular SPICE simulator, increasing accuracy of the final results, without violating any of the key principles of the traditional design scheme.

  2. Electronic Design Automation Using Object Oriented Electronics

    OpenAIRE

    Walid M. Aly; Mohamed S. Abuelnasr

    2010-01-01

    Problem statement: Electronic design automation is the usage of computer technology and software tools for designing integrated electronic system and creating electrical schematics. Approach: An approach is presented for modeling of various electronic and electric devices using object oriented design, aiming on building a library of devices (classes) which can be used for electronic design automation. Results: The presented library was implemented using Java programming language to form an El...

  3. Electronic automation of LRFD design programs.

    Science.gov (United States)

    2010-03-01

    The study provided electronic programs to WisDOT for designing pre-stressed girders and piers using the Load : Resistance Factor Design (LRFD) methodology. The software provided is intended to ease the transition to : LRFD for WisDOT design engineers...

  4. Using digital electronic design flow to create a Genetic Design Automation tool.

    Science.gov (United States)

    Gendrault, Y; Madec, M; Wlotzko, V; Andraud, M; Lallement, C; Haiech, J

    2012-01-01

    Synthetic bio-systems become increasingly more complex and their development is lengthy and expensive. In the same way, in microelectronics, the design process of very complex circuits has benefited from many years of experience. It is now partly automated through Electronic Design Automation tools. Both areas present analogies that can be used to create a Genetic Design Automation tool inspired from EDA tools used in digital electronics. This tool would allow moving away from a totally manual design of bio-systems to assisted conception. This ambitious project is presented in this paper, with a deep focus on the tool that automatically generates models of bio-systems directly usable in electronic simulators.

  5. A Parallel Genetic Algorithm for Automated Electronic Circuit Design

    Science.gov (United States)

    Long, Jason D.; Colombano, Silvano P.; Haith, Gary L.; Stassinopoulos, Dimitris

    2000-01-01

    Parallelized versions of genetic algorithms (GAs) are popular primarily for three reasons: the GA is an inherently parallel algorithm, typical GA applications are very compute intensive, and powerful computing platforms, especially Beowulf-style computing clusters, are becoming more affordable and easier to implement. In addition, the low communication bandwidth required allows the use of inexpensive networking hardware such as standard office ethernet. In this paper we describe a parallel GA and its use in automated high-level circuit design. Genetic algorithms are a type of trial-and-error search technique that are guided by principles of Darwinian evolution. Just as the genetic material of two living organisms can intermix to produce offspring that are better adapted to their environment, GAs expose genetic material, frequently strings of 1s and Os, to the forces of artificial evolution: selection, mutation, recombination, etc. GAs start with a pool of randomly-generated candidate solutions which are then tested and scored with respect to their utility. Solutions are then bred by probabilistically selecting high quality parents and recombining their genetic representations to produce offspring solutions. Offspring are typically subjected to a small amount of random mutation. After a pool of offspring is produced, this process iterates until a satisfactory solution is found or an iteration limit is reached. Genetic algorithms have been applied to a wide variety of problems in many fields, including chemistry, biology, and many engineering disciplines. There are many styles of parallelism used in implementing parallel GAs. One such method is called the master-slave or processor farm approach. In this technique, slave nodes are used solely to compute fitness evaluations (the most time consuming part). The master processor collects fitness scores from the nodes and performs the genetic operators (selection, reproduction, variation, etc.). Because of dependency

  6. The design of the automated control system for warehouse equipment under radio-electronic manufacturing

    Science.gov (United States)

    Kapulin, D. V.; Chemidov, I. V.; Kazantsev, M. A.

    2017-01-01

    In the paper, the aspects of design, development and implementation of the automated control system for warehousing under the manufacturing process of the radio-electronic enterprise JSC «Radiosvyaz» are discussed. The architecture of the automated control system for warehousing proposed in the paper consists of a server which is connected to the physically separated information networks: the network with a database server, which stores information about the orders for picking, and the network with the automated storage and retrieval system. This principle allows implementing the requirements for differentiation of access, ensuring the information safety and security requirements. Also, the efficiency of the developed automated solutions in terms of optimizing the warehouse’s logistic characteristics is researched.

  7. Electronic design automation of analog ICs combining gradient models with multi-objective evolutionary algorithms

    CERN Document Server

    Rocha, Frederico AE; Lourenço, Nuno CC; Horta, Nuno CG

    2013-01-01

    This book applies to the scientific area of electronic design automation (EDA) and addresses the automatic sizing of analog integrated circuits (ICs). Particularly, this book presents an approach to enhance a state-of-the-art layout-aware circuit-level optimizer (GENOM-POF), by embedding statistical knowledge from an automatically generated gradient model into the multi-objective multi-constraint optimization kernel based on the NSGA-II algorithm. The results showed allow the designer to explore the different trade-offs of the solution space, both through the achieved device sizes, or the resp

  8. DEVELOPMENT AND TESTING OF ERRORS CORRECTION ALGORITHM IN ELECTRONIC DESIGN AUTOMATION

    Directory of Open Access Journals (Sweden)

    E. B. Romanova

    2016-03-01

    Full Text Available Subject of Research. We have developed and presented a method of design errors correction for printed circuit boards (PCB in electronic design automation (EDA. Control of process parameters of PCB in EDA is carried out by means of Design Rule Check (DRC program. The DRC program monitors compliance with the design rules (minimum width of the conductors and gaps, the parameters of pads and via-holes, the parameters of polygons, etc. and also checks the route tracing, short circuits, the presence of objects outside PCB edge and other design errors. The result of the DRC program running is the generated error report. For quality production of circuit boards DRC-errors should be corrected, that is ensured by the creation of error-free DRC report. Method. A problem of correction repeatability of DRC-errors was identified as a result of trial operation of P-CAD, Altium Designer and KiCAD programs. For its solution the analysis of DRC-errors was carried out; the methods of their correction were studied. DRC-errors were proposed to be clustered. Groups of errors include the types of errors, which correction sequence has no impact on the correction time. The algorithm for correction of DRC-errors is proposed. Main Results. The best correction sequence of DRC-errors has been determined. The algorithm has been tested in the following EDA: P-CAD, Altium Designer and KiCAD. Testing has been carried out on two and four-layer test PCB (digital and analog. Comparison of DRC-errors correction time with the algorithm application to the same time without it has been done. It has been shown that time saved for the DRC-errors correction increases with the number of error types up to 3.7 times. Practical Relevance. The proposed algorithm application will reduce PCB design time and improve the quality of the PCB design. We recommend using the developed algorithm when the number of error types is equal to four or more. The proposed algorithm can be used in different

  9. Design automation, languages, and simulations

    CERN Document Server

    Chen, Wai-Kai

    2003-01-01

    As the complexity of electronic systems continues to increase, the micro-electronic industry depends upon automation and simulations to adapt quickly to market changes and new technologies. Compiled from chapters contributed to CRC's best-selling VLSI Handbook, this volume covers a broad range of topics relevant to design automation, languages, and simulations. These include a collaborative framework that coordinates distributed design activities through the Internet, an overview of the Verilog hardware description language and its use in a design environment, hardware/software co-design, syst

  10. Mechatronic Design Automation

    DEFF Research Database (Denmark)

    Fan, Zhun

    This book proposes a novel design method that combines both genetic programming (GP) to automatically explore the open-ended design space and bond graphs (BG) to unify design representations of multi-domain Mechatronic systems. Results show that the method, formally called GPBG method, can...... successfully design analogue filters, vibration absorbers, micro-electro-mechanical systems, and vehicle suspension systems, all in an automatic or semi-automatic way. It also investigates the very important issue of co-designing plant-structures and dynamic controllers in automated design of Mechatronic...

  11. Design automation for integrated optics

    Science.gov (United States)

    Condrat, Christopher

    Recent breakthroughs in silicon photonics technology are enabling the integration of optical devices into silicon-based semiconductor processes. Photonics technology enables high-speed, high-bandwidth, and high-fidelity communications on the chip-scale---an important development in an increasingly communications-oriented semiconductor world. Significant developments in silicon photonic manufacturing and integration are also enabling investigations into applications beyond that of traditional telecom: sensing, filtering, signal processing, quantum technology---and even optical computing. In effect, we are now seeing a convergence of communications and computation, where the traditional roles of optics and microelectronics are becoming blurred. As the applications for opto-electronic integrated circuits (OEICs) are developed, and manufacturing capabilities expand, design support is necessary to fully exploit the potential of this optics technology. Such design support for moving beyond custom-design to automated synthesis and optimization is not well developed. Scalability requires abstractions, which in turn enables and requires the use of optimization algorithms and design methodology flows. Design automation represents an opportunity to take OEIC design to a larger scale, facilitating design-space exploration, and laying the foundation for current and future optical applications---thus fully realizing the potential of this technology. This dissertation proposes design automation for integrated optic system design. Using a building-block model for optical devices, we provide an EDA-inspired design flow and methodologies for optical design automation. Underlying these flows and methodologies are new supporting techniques in behavioral and physical synthesis, as well as device-resynthesis techniques for thermal-aware system integration. We also provide modeling for optical devices and determine optimization and constraint parameters that guide the automation

  12. Making Money from Exploiting Schumpeterian Opportunities: John Sanguinetti and the Electronic Design Automation Industry

    Directory of Open Access Journals (Sweden)

    Arthur Low

    2012-05-01

    Full Text Available Accounts of the effect that John Sanguinetti’s two companies had on the market for integrated circuit design languages were used to gain insights on how to profit from the exploitation of Schumpeterian opportunities. This article will be of interest to entrepreneurs who expect to profit from exploiting opportunities that disrupt the status quo. To write this article, the author reviewed the literature on Schumpeterian and Kirznerian opportunities and examined the writings of and about Sanguinetti and his companies, blogs written by industry insiders, and articles in industry trade journals. Sanguinetti’s first company introduced a new technology and his second company introduced a new business strategy and a new technology. Both of Sanguinetti's companies undermined the capital investments of the established incumbents and created new value for customers. The article provides three main insights. First, deep knowledge and experience in the customer domain enable an entrepreneur to recognize and act to profit from a Schumpeterian opportunity. Second, to profit from a Schumpeterian opportunity the entrepreneur needs to combine technology and business model components in a way that adds significant value to customers. Third, large amounts of venture capital may or may not be required to exploit Schumpeterian opportunities.

  13. Towards Automated Nanomanipulation under Scanning Electron Microscopy

    Science.gov (United States)

    Ye, Xutao

    Robotic Nanomaterial Manipulation inside scanning electron microscopes (SEM) is useful for prototyping functional devices and characterizing one-dimensional nanomaterial's properties. Conventionally, manipulation of nanowires has been performed via teleoperation, which is time-consuming and highly skill-dependent. Manual manipulation also has the limitation of low success rates and poor reproducibility. This research focuses on a robotic system capable of automated pick-place of single nanowires. Through SEM visual detection and vision-based motion control, the system transferred individual silicon nanowires from their growth substrate to a microelectromechanical systems (MEMS) device that characterized the nanowires' electromechanical properties. The performances of the nanorobotic pick-up and placement procedures were quantified by experiments. The system demonstrated automated nanowire pick-up and placement with high reliability. A software system for a load-lock-compatible nanomanipulation system is also designed and developed in this research.

  14. Design Automation in Synthetic Biology.

    Science.gov (United States)

    Appleton, Evan; Madsen, Curtis; Roehner, Nicholas; Densmore, Douglas

    2017-04-03

    Design automation refers to a category of software tools for designing systems that work together in a workflow for designing, building, testing, and analyzing systems with a target behavior. In synthetic biology, these tools are called bio-design automation (BDA) tools. In this review, we discuss the BDA tools areas-specify, design, build, test, and learn-and introduce the existing software tools designed to solve problems in these areas. We then detail the functionality of some of these tools and show how they can be used together to create the desired behavior of two types of modern synthetic genetic regulatory networks. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

  15. Electron beam welding complex diagnostics automated system

    Directory of Open Access Journals (Sweden)

    Є. В. Нікітенко

    2013-07-01

    Full Text Available The structure of the system of technical diagnostics is investigated. The algorithm of technical diagnostic of electron beam welding complex, which serves as the basis for creation of automated system for technical diagnostics, is proposed

  16. Automated extraction system design review

    Energy Technology Data Exchange (ETDEWEB)

    Parry, H.L.; Eklund, J.D.; Halter, J.M.; Sullivan, R.G.

    1979-03-01

    The Automated Extraction System (AES) is an advanced fullface continuous mining system designed and built by National Mine Service Co. Since initial testing in a coal mine revealed operational problems, a design review was conducted. Two potential conceptual problems were identified: the roof control concept and the hydraulic sumping concept. It is felt that the combination of uneven and cyclic roof loading may promote roof failure even in bolted roof areas. Critical design problem areas include weight and balance, friction-induced excessive sumping forces, and design complexity.

  17. Automated Design of Quantum Circuits

    Science.gov (United States)

    Williams, Colin P.; Gray, Alexander G.

    2000-01-01

    In order to design a quantum circuit that performs a desired quantum computation, it is necessary to find a decomposition of the unitary matrix that represents that computation in terms of a sequence of quantum gate operations. To date, such designs have either been found by hand or by exhaustive enumeration of all possible circuit topologies. In this paper we propose an automated approach to quantum circuit design using search heuristics based on principles abstracted from evolutionary genetics, i.e. using a genetic programming algorithm adapted specially for this problem. We demonstrate the method on the task of discovering quantum circuit designs for quantum teleportation. We show that to find a given known circuit design (one which was hand-crafted by a human), the method considers roughly an order of magnitude fewer designs than naive enumeration. In addition, the method finds novel circuit designs superior to those previously known.

  18. Proceedings of Design, Automation and Test in Europe (DATE07)

    DEFF Research Database (Denmark)

    Welcome to the DATE 07 Conference Proceedings. DATE combines the world’s leading electronic systems design conference and Europe's leading international exhibition for electronic design, automation and test, from system level hardware and software implementation right down to integrated circuit...... with 78 sessions covering the latest in system design and embedded software, IC design methodologies and EDA tool developments. One of the main strengths of the conference is a wide but high-quality coverage of design, design automation and test topics, from the system level (including PCB and FPGA...

  19. Antenna arrays: waveguide layout designing automation

    OpenAIRE

    Anamova, R. R.

    2014-01-01

    Waveguide layout designing automation in the large-sized phased antenna arrays is studied. A new methodology of the automation and algorithms based on the flexible connection routing method are suggested. Results are realized in the software module WDS (Waveguide Design Solution) based on SolidWorks system. This module gives an opportunity to decrease design and engineering time and costs.

  20. Automation bias in electronic prescribing.

    Science.gov (United States)

    Lyell, David; Magrabi, Farah; Raban, Magdalena Z; Pont, L G; Baysari, Melissa T; Day, Richard O; Coiera, Enrico

    2017-03-16

    Clinical decision support (CDS) in e-prescribing can improve safety by alerting potential errors, but introduces new sources of risk. Automation bias (AB) occurs when users over-rely on CDS, reducing vigilance in information seeking and processing. Evidence of AB has been found in other clinical tasks, but has not yet been tested with e-prescribing. This study tests for the presence of AB in e-prescribing and the impact of task complexity and interruptions on AB. One hundred and twenty students in the final two years of a medical degree prescribed medicines for nine clinical scenarios using a simulated e-prescribing system. Quality of CDS (correct, incorrect and no CDS) and task complexity (low, low + interruption and high) were varied between conditions. Omission errors (failure to detect prescribing errors) and commission errors (acceptance of false positive alerts) were measured. Compared to scenarios with no CDS, correct CDS reduced omission errors by 38.3% (p < .0001, n = 120), 46.6% (p < .0001, n = 70), and 39.2% (p < .0001, n = 120) for low, low + interrupt and high complexity scenarios respectively. Incorrect CDS increased omission errors by 33.3% (p < .0001, n = 120), 24.5% (p < .009, n = 82), and 26.7% (p < .0001, n = 120). Participants made commission errors, 65.8% (p < .0001, n = 120), 53.5% (p < .0001, n = 82), and 51.7% (p < .0001, n = 120). Task complexity and interruptions had no impact on AB. This study found evidence of AB omission and commission errors in e-prescribing. Verification of CDS alerts is key to avoiding AB errors. However, interventions focused on this have had limited success to date. Clinicians should remain vigilant to the risks of CDS failures and verify CDS.

  1. Generic Automated Multi-function Finger Design

    Science.gov (United States)

    Honarpardaz, M.; Tarkian, M.; Sirkett, D.; Ölvander, J.; Feng, X.; Elf, J.; Sjögren, R.

    2016-11-01

    Multi-function fingers that are able to handle multiple workpieces are crucial in improvement of a robot workcell. Design automation of multi-function fingers is highly demanded by robot industries to overcome the current iterative, time consuming and complex manual design process. However, the existing approaches for the multi-function finger design automation are unable to entirely meet the robot industries’ need. This paper proposes a generic approach for design automation of multi-function fingers. The proposed approach completely automates the design process and requires no expert skill. In addition, this approach executes the design process much faster than the current manual process. To validate the approach, multi-function fingers are successfully designed for two case studies. Further, the results are discussed and benchmarked with existing approaches.

  2. Automated data collection in single particle electron microscopy

    Science.gov (United States)

    Tan, Yong Zi; Cheng, Anchi; Potter, Clinton S.; Carragher, Bridget

    2016-01-01

    Automated data collection is an integral part of modern workflows in single particle electron microscopy (EM) research. This review surveys the software packages available for automated single particle EM data collection. The degree of automation at each stage of data collection is evaluated, and the capabilities of the software packages are described. Finally, future trends in automation are discussed. PMID:26671944

  3. Conceptual design of automated freight transport systems

    NARCIS (Netherlands)

    Pielage, B.A.

    2005-01-01

    The conceptual design of automated freight transport systems is a challenging matter. It involves many different parties, types of people and disciplines which all have to work together to develop a system which is often new and complex. Automated freight transport systems typically have a long

  4. Proceedings of Design, Automation and Test in Europe (DATE07)

    DEFF Research Database (Denmark)

    Welcome to the DATE 07 Conference Proceedings. DATE combines the world’s leading electronic systems design conference and Europe's leading international exhibition for electronic design, automation and test, from system level hardware and software implementation right down to integrated circuit....... Challenges that you all face or soon will face in your daily practice are the increasing design complexity of highly integrated systems, the introduction of reconfigurability and embedded software, and the control of power, reliability and variability in nanometer IC designs. All these issues...... with 78 sessions covering the latest in system design and embedded software, IC design methodologies and EDA tool developments. One of the main strengths of the conference is a wide but high-quality coverage of design, design automation and test topics, from the system level (including PCB and FPGA...

  5. Automated protein design: Landmarks and operational principles.

    Science.gov (United States)

    Kumar, Anil; Ranbhor, Ranjit; Patel, Kirti; Ramakrishnan, Vibin; Durani, Susheel

    2017-05-01

    Protein design has an eventful history spanning over three decades, with handful of success stories reported, and numerous failures not reported. Design practices have benefited tremendously from improvements in computer hardware and advances in scientific algorithms. Though protein folding problem still remains unsolved, the possibility of having multiple sequence solutions for a single fold makes protein design a more tractable problem than protein folding. One of the most significant advancement in this area is the implementation of automated design algorithms on pre-defined templates or completely new folds, optimized through deterministic and heuristic search algorithms. This progress report provides a succinct presentation of important landmarks in automated design attempts, followed by brief account of operational principles in automated design methods. Copyright © 2016 Elsevier Ltd. All rights reserved.

  6. Automotive electronics design fundamentals

    CERN Document Server

    Zaman, Najamuz

    2015-01-01

    This book explains the topology behind automotive electronics architectures and examines how they can be profoundly augmented with embedded controllers. These controllers serve as the core building blocks of today’s vehicle electronics. Rather than simply teaching electrical basics, this unique resource focuses on the fundamental concepts of vehicle electronics architecture, and details the wide variety of Electronic Control Modules (ECMs) that enable the increasingly sophisticated "bells & whistles" of modern designs.  A must-have for automotive design engineers, technicians working in automotive electronics repair centers and students taking automotive electronics courses, this guide bridges the gap between academic instruction and industry practice with clear, concise advice on how to design and optimize automotive electronics with embedded controllers.

  7. Designing a Software Test Automation Framework

    Directory of Open Access Journals (Sweden)

    Sabina AMARICAI

    2014-01-01

    Full Text Available Testing is an art and science that should ultimately lead to lower cost businesses through increasing control and reducing risk. Testing specialists should thoroughly understand the system or application from both the technical and the business perspective, and then design, build and implement the minimum-cost, maximum-coverage validation framework. Test Automation is an important ingredient for testing large scale applications. In this paper we discuss several test automation frameworks, their advantages and disadvantages. We also propose a custom automation framework model that is suited for applications with very complex business requirements and numerous interfaces.

  8. Local Automation Model: Conceptual Design Document,

    Science.gov (United States)

    1983-04-01

    AD A144 383 LOCAL AUTOMATION MODEL CONCEPTA DA ESIG N DOCUMENTU 1/ LOGISTCS MANAGEMENT IN WASHINOTON DC W P HAMILTON ET AL. APR 83 LMI-DL302 MDA903...STATEMENT (of the abstract entered in Block 20, if different from Report) I8. SUPPLEMENTARY NOTES 19. KEY WORDS (Continue on reverse side if necessary...ABSTRACT (Continue on reverse side if necessary and identify by block number) This document contains a conceptual design for the Local Automation

  9. Designing a Software Test Automation Framework

    OpenAIRE

    Sabina AMARICAI; Constantinescu, Radu

    2014-01-01

    Testing is an art and science that should ultimately lead to lower cost businesses through increasing control and reducing risk. Testing specialists should thoroughly understand the system or application from both the technical and the business perspective, and then design, build and implement the minimum-cost, maximum-coverage validation framework. Test Automation is an important ingredient for testing large scale applications. In this paper we discuss several test automation frameworks, th...

  10. Automating InDesign with Regular Expressions

    CERN Document Server

    Kahrel, Peter

    2006-01-01

    If you need to make automated changes to InDesign documents beyond what basic search and replace can handle, you need regular expressions, and a bit of scripting to make them work. This Short Cut explains both how to write regular expressions, so you can find and replace the right things, and how to use them in InDesign specifically.

  11. An Automated Approach to Instructional Design Guidance.

    Science.gov (United States)

    Spector, J. Michael; And Others

    This paper describes the Guided Approach to Instructional Design Advising (GAIDA), an automated instructional design tool that incorporates techniques of artificial intelligence. GAIDA was developed by the U.S. Air Force Armstrong Laboratory to facilitate the planning and production of interactive courseware and computer-based training materials.…

  12. Automated Quantitative Rare Earth Elements Mineralogy by Scanning Electron Microscopy

    Science.gov (United States)

    Sindern, Sven; Meyer, F. Michael

    2016-09-01

    Increasing industrial demand of rare earth elements (REEs) stems from the central role they play for advanced technologies and the accelerating move away from carbon-based fuels. However, REE production is often hampered by the chemical, mineralogical as well as textural complexity of the ores with a need for better understanding of their salient properties. This is not only essential for in-depth genetic interpretations but also for a robust assessment of ore quality and economic viability. The design of energy and cost-efficient processing of REE ores depends heavily on information about REE element deportment that can be made available employing automated quantitative process mineralogy. Quantitative mineralogy assigns numeric values to compositional and textural properties of mineral matter. Scanning electron microscopy (SEM) combined with a suitable software package for acquisition of backscatter electron and X-ray signals, phase assignment and image analysis is one of the most efficient tools for quantitative mineralogy. The four different SEM-based automated quantitative mineralogy systems, i.e. FEI QEMSCAN and MLA, Tescan TIMA and Zeiss Mineralogic Mining, which are commercially available, are briefly characterized. Using examples of quantitative REE mineralogy, this chapter illustrates capabilities and limitations of automated SEM-based systems. Chemical variability of REE minerals and analytical uncertainty can reduce performance of phase assignment. This is shown for the REE phases parisite and synchysite. In another example from a monazite REE deposit, the quantitative mineralogical parameters surface roughness and mineral association derived from image analysis are applied for automated discrimination of apatite formed in a breakdown reaction of monazite and apatite formed by metamorphism prior to monazite breakdown. SEM-based automated mineralogy fulfils all requirements for characterization of complex unconventional REE ores that will become

  13. Automated solar collector installation design

    Science.gov (United States)

    Wayne, Gary; Frumkin, Alexander; Zaydman, Michael; Lehman, Scott; Brenner, Jules

    2014-08-26

    Embodiments may include systems and methods to create and edit a representation of a worksite, to create various data objects, to classify such objects as various types of pre-defined "features" with attendant properties and layout constraints. As part of or in addition to classification, an embodiment may include systems and methods to create, associate, and edit intrinsic and extrinsic properties to these objects. A design engine may apply of design rules to the features described above to generate one or more solar collectors installation design alternatives, including generation of on-screen and/or paper representations of the physical layout or arrangement of the one or more design alternatives.

  14. Knowledge engineering for design automation

    NARCIS (Netherlands)

    Schotborgh, W.O.

    2009-01-01

    Engineering design teams face many challenges, one of which is the time pressure on the product creation process. A wide range of Information and Communications Technology solutions is available to relieve the time pressure and increase overall efficiency. A promising type of software is that which

  15. Automated mixed traffic vehicle design AMTV 2

    Science.gov (United States)

    Johnston, A. R.; Marks, R. A.; Cassell, P. L.

    1982-01-01

    The design of an improved and enclosed Automated Mixed Traffic Transit (AMTT) vehicle is described. AMTT is an innovative concept for low-speed tram-type transit in which suitable vehicles are equipped with sensors and controls to permit them to operate in an automated mode on existing road or walkway surfaces. The vehicle chassis and body design are presented in terms of sketches and photographs. The functional design of the sensing and control system is presented, and modifications which could be made to the baseline design for improved performance, in particular to incorporate a 20-mph capability, are also discussed. The vehicle system is described at the block-diagram-level of detail. Specifications and parameter values are given where available.

  16. Controller Design Automation for Aeroservoelastic Design Optimization of Wind Turbines

    NARCIS (Netherlands)

    Ashuri, T.; Van Bussel, G.J.W.; Zaayer, M.B.; Van Kuik, G.A.M.

    2010-01-01

    The purpose of this paper is to integrate the controller design of wind turbines with structure and aerodynamic analysis and use the final product in the design optimization process (DOP) of wind turbines. To do that, the controller design is automated and integrated with an aeroelastic simulation

  17. Proceedings of Design, Automation and Test in Europe (DATE07)

    DEFF Research Database (Denmark)

    Welcome to the DATE 07 Conference Proceedings. DATE combines the world’s leading electronic systems design conference and Europe's leading international exhibition for electronic design, automation and test, from system level hardware and software implementation right down to integrated circuit...... an international conference. DATE is now the world’s premier event in electronic system design. The submissions have been reviewed by the more than 600 members of the Technical Programme Committee. After a thorough review and selection process (with an average of 4.6 reviews per paper), finally 208 papers were......) to the integrated circuit level. In addition, for the third year a special embedded software track is offered to allow for the increasing importance of software in embedded systems. Compared with previous years, submissions in design, test and embedded software have grown significantly, showing a clear trend toward...

  18. Designing and implementing test automation frameworks with QTP

    CERN Document Server

    Bhargava, Ashish

    2013-01-01

    A tutorial-based approach, showing basic coding and designing techniques to build test automation frameworks.If you are a beginner, an automation engineer, an aspiring test automation engineer, a manual tester, a test lead or a test architect who wants to learn, create, and maintain test automation frameworks, this book will accelerate your ability to develop and adapt the framework.

  19. Mask design automation: an integrated approach

    Science.gov (United States)

    Gladhill, Richard; Buck, Peter; Wong, Al

    2012-11-01

    Mask Design, or the process of assembling, arranging and configuring the pattern data required to make a photomask, has many characteristics that make it appropriate for automation, including a high order of complexity, many steps in the process flow, many parameters to define, and multiple flow variants. Traditionally Mask Design has been performed in several discrete steps, each having its own set of tools, processes, data formats, and parameter sets. These include, for example, Boolean layer extraction, fill pattern generation, biasing, Optical Process Compensation (OPC), frame generation (assembling the patterns relevant to reticle and wafer alignment, automated bar code identification, masking/taping borders, process control monitors and test patterns); fracture (transforming design data formats into mask write tool formats); jobdeck generation (creating the mask write tool instruction set); and Mask Rule Checking (MRC). These separate, and often non-compatible, process flows make integration challenging. Additionally, the frame generation process typically has evolved in complexity ad hoc and is often not performed in a systematic manner that makes it easily adaptable to automation.

  20. Proceedings of Design, Automation and Test in Europe (DATE07)

    DEFF Research Database (Denmark)

    Welcome to the DATE 07 Conference Proceedings. DATE combines the world’s leading electronic systems design conference and Europe's leading international exhibition for electronic design, automation and test, from system level hardware and software implementation right down to integrated circuit...... an international conference. DATE is now the world’s premier event in electronic system design. The submissions have been reviewed by the more than 600 members of the Technical Programme Committee. After a thorough review and selection process (with an average of 4.6 reviews per paper), finally 208 papers were...... selected for presentation at the conference. In addition, 57 papers were selected for Interactive Presentations, which highlight quality work in progress. Together with the invited special sessions (panels, embedded tutorials and hot topic sessions) this has resulted in a high-quality technical programme...

  1. AUTOMATION DESIGN FOR MONORAIL - BASED SYSTEM PROCESSES

    Directory of Open Access Journals (Sweden)

    Bunda BESA

    2016-12-01

    Full Text Available Currently, conventional methods of decline development put enormous cost pressure on the profitability of mining operations. This is the case with narrow vein ore bodies where current methods and mine design of decline development may be too expensive to support economic extraction of the ore. According to studies, the time it takes to drill, clean and blast an end in conventional decline development can be up to 224 minutes. This is because once an end is blasted, cleaning should first be completed before drilling can commence, resulting in low advance rates per shift. Improvements in advance rates during decline development can be achieved by application of the Electric Monorail Transport System (EMTS based drilling system. The system consists of the drilling and loading components that use monorail technology to drill and clean the face during decline development. The two systems work simultaneously at the face in such a way that as the top part of the face is being drilled the pneumatic loading system cleans the face. However, to improve the efficiency of the two systems, critical processes performed by the two systems during mining operations must be automated. Automation increases safety and productivity, reduces operator fatigue and also reduces the labour costs of the system. The aim of this paper is, therefore, to describe automation designs of the two processes performed by the monorail drilling and loading systems during operations. During automation design, critical processes performed by the two systems and control requirements necessary to allow the two systems execute such processes automatically have also been identified.

  2. AuTom: a novel automatic platform for electron tomography reconstruction

    KAUST Repository

    Han, Renmin

    2017-07-26

    We have developed a software package towards automatic electron tomography (ET): Automatic Tomography (AuTom). The presented package has the following characteristics: accurate alignment modules for marker-free datasets containing substantial biological structures; fully automatic alignment modules for datasets with fiducial markers; wide coverage of reconstruction methods including a new iterative method based on the compressed-sensing theory that suppresses the “missing wedge” effect; and multi-platform acceleration solutions that support faster iterative algebraic reconstruction. AuTom aims to achieve fully automatic alignment and reconstruction for electron tomography and has already been successful for a variety of datasets. AuTom also offers user-friendly interface and auxiliary designs for file management and workflow management, in which fiducial marker-based datasets and marker-free datasets are addressed with totally different subprocesses. With all of these features, AuTom can serve as a convenient and effective tool for processing in electron tomography.

  3. Co-creative design developments for accessibility and home automation

    OpenAIRE

    Taib, SM; De Coster, R; Sabri Tekantape, E

    2017-01-01

    The term “Home Automation” can be referred to a networked home, which provides electronically controlled security and convenience for its users. Home automation is also defined as the integration of home-based technology and services for a better quality of living (Quynh, et al., 2012). The main purpose of home automation technologies is to enhance home comfort for everyone through the automation of higher security, domestic tasks and easy communication. Home automation should be able to enha...

  4. Automating risk analysis of software design models.

    Science.gov (United States)

    Frydman, Maxime; Ruiz, Guifré; Heymann, Elisa; César, Eduardo; Miller, Barton P

    2014-01-01

    The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development lifecycle. This paper describes an approach to reduce the need for costly human expertise to perform risk analysis in software, which is common in secure development methodologies, by automating threat modeling. Reducing the dependency on security experts aims at reducing the cost of secure development by allowing non-security-aware developers to apply secure development with little to no additional cost, making secure development more accessible. To automate threat modeling two data structures are introduced, identification trees and mitigation trees, to identify threats in software designs and advise mitigation techniques, while taking into account specification requirements and cost concerns. These are the components of our model for automated threat modeling, AutSEC. We validated AutSEC by implementing it in a tool based on data flow diagrams, from the Microsoft security development methodology, and applying it to VOMS, a grid middleware component, to evaluate our model's performance.

  5. Automating Risk Analysis of Software Design Models

    Directory of Open Access Journals (Sweden)

    Maxime Frydman

    2014-01-01

    Full Text Available The growth of the internet and networked systems has exposed software to an increased amount of security threats. One of the responses from software developers to these threats is the introduction of security activities in the software development lifecycle. This paper describes an approach to reduce the need for costly human expertise to perform risk analysis in software, which is common in secure development methodologies, by automating threat modeling. Reducing the dependency on security experts aims at reducing the cost of secure development by allowing non-security-aware developers to apply secure development with little to no additional cost, making secure development more accessible. To automate threat modeling two data structures are introduced, identification trees and mitigation trees, to identify threats in software designs and advise mitigation techniques, while taking into account specification requirements and cost concerns. These are the components of our model for automated threat modeling, AutSEC. We validated AutSEC by implementing it in a tool based on data flow diagrams, from the Microsoft security development methodology, and applying it to VOMS, a grid middleware component, to evaluate our model's performance.

  6. Automated firewall analytics design, configuration and optimization

    CERN Document Server

    Al-Shaer, Ehab

    2014-01-01

    This book provides a comprehensive and in-depth study of automated firewall policy analysis for designing, configuring and managing distributed firewalls in large-scale enterpriser networks. It presents methodologies, techniques and tools for researchers as well as professionals to understand the challenges and improve the state-of-the-art of managing firewalls systematically in both research and application domains. Chapters explore set-theory, managing firewall configuration globally and consistently, access control list with encryption, and authentication such as IPSec policies. The author

  7. Automated design of genomic Southern blot probes

    Directory of Open Access Journals (Sweden)

    Komiyama Noboru H

    2010-01-01

    experimentally validate a number of these automated designs by Southern blotting. The majority of probes we tested performed well confirming our in silico prediction methodology and the general usefulness of the software for automated genomic Southern probe design. Conclusions Software and supplementary information are freely available at: http://www.genes2cognition.org/software/southern_blot

  8. Team-Centered Perspective for Adaptive Automation Design

    Science.gov (United States)

    Prinzel, Lawrence J., III

    2003-01-01

    Automation represents a very active area of human factors research. The journal, Human Factors, published a special issue on automation in 1985. Since then, hundreds of scientific studies have been published examining the nature of automation and its interaction with human performance. However, despite a dramatic increase in research investigating human factors issues in aviation automation, there remain areas that need further exploration. This NASA Technical Memorandum describes a new area of automation design and research, called adaptive automation. It discusses the concepts and outlines the human factors issues associated with the new method of adaptive function allocation. The primary focus is on human-centered design, and specifically on ensuring that adaptive automation is from a team-centered perspective. The document shows that adaptive automation has many human factors issues common to traditional automation design. Much like the introduction of other new technologies and paradigm shifts, adaptive automation presents an opportunity to remediate current problems but poses new ones for human-automation interaction in aerospace operations. The review here is intended to communicate the philosophical perspective and direction of adaptive automation research conducted under the Aerospace Operations Systems (AOS), Physiological and Psychological Stressors and Factors (PPSF) project.

  9. Designing automated warehouses by minimising investment cost using genetic algorithms

    OpenAIRE

    Lerher, Tone; Potrč, Iztok; Šraml, Matjaž

    2012-01-01

    The successful performance of the automated storage and retrieval systems is dependent upon the appropriate design and optimization process. In the present work a comprehensive model of designing automated storage and retrieval system for the single- and multi-aisle systems is presented. Because of the required conditions that the automated storage and retrieval systems should be technically highly efficient and that it should be designed on reasonable expenses, the objective function represe...

  10. Automated Antenna Design with Evolutionary Algorithms

    Science.gov (United States)

    Hornby, Gregory S.; Globus, Al; Linden, Derek S.; Lohn, Jason D.

    2006-01-01

    Current methods of designing and optimizing antennas by hand are time and labor intensive, and limit complexity. Evolutionary design techniques can overcome these limitations by searching the design space and automatically finding effective solutions. In recent years, evolutionary algorithms have shown great promise in finding practical solutions in large, poorly understood design spaces. In particular, spacecraft antenna design has proven tractable to evolutionary design techniques. Researchers have been investigating evolutionary antenna design and optimization since the early 1990s, and the field has grown in recent years as computer speed has increased and electromagnetic simulators have improved. Two requirements-compliant antennas, one for ST5 and another for TDRS-C, have been automatically designed by evolutionary algorithms. The ST5 antenna is slated to fly this year, and a TDRS-C phased array element has been fabricated and tested. Such automated evolutionary design is enabled by medium-to-high quality simulators and fast modern computers to evaluate computer-generated designs. Evolutionary algorithms automate cut-and-try engineering, substituting automated search though millions of potential designs for intelligent search by engineers through a much smaller number of designs. For evolutionary design, the engineer chooses the evolutionary technique, parameters and the basic form of the antenna, e.g., single wire for ST5 and crossed-element Yagi for TDRS-C. Evolutionary algorithms then search for optimal configurations in the space defined by the engineer. NASA's Space Technology 5 (ST5) mission will launch three small spacecraft to test innovative concepts and technologies. Advanced evolutionary algorithms were used to automatically design antennas for ST5. The combination of wide beamwidth for a circularly-polarized wave and wide impedance bandwidth made for a challenging antenna design problem. From past experience in designing wire antennas, we chose to

  11. Design and Implementation of Microcontroller based Automated Air ...

    African Journals Online (AJOL)

    Design and Implementation of Microcontroller based Automated Air Conditioning Control System for Refrigerator Truck. Frezer Getachew, Helen Nekatibeb, Samuel Workineh, Tesfaye Yitbarek, Yibeltal Gelaye, Taye Girma ...

  12. Automated Sensitivity Analysis of Interplanetary Trajectories for Optimal Mission Design

    Science.gov (United States)

    Knittel, Jeremy; Hughes, Kyle; Englander, Jacob; Sarli, Bruno

    2017-01-01

    This work describes a suite of Python tools known as the Python EMTG Automated Trade Study Application (PEATSA). PEATSA was written to automate the operation of trajectory optimization software, simplify the process of performing sensitivity analysis, and was ultimately found to out-perform a human trajectory designer in unexpected ways. These benefits will be discussed and demonstrated on sample mission designs.

  13. Ecological Automation Design, Extending Work Domain Analysis

    NARCIS (Netherlands)

    Amelink, M.H.J.

    2010-01-01

    In high–risk domains like aviation, medicine and nuclear power plant control, automation has enabled new capabilities, increased the economy of operation and has greatly contributed to safety. However, automation increases the number of couplings in a system, which can inadvertently lead to more

  14. Design automation for integrated nonlinear logic circuits (Conference Presentation)

    Science.gov (United States)

    Van Vaerenbergh, Thomas; Pelc, Jason; Santori, Charles; Bose, Ranojoy; Kielpinski, Dave; Beausoleil, Raymond G.

    2016-05-01

    A key enabler of the IT revolution of the late 20th century was the development of electronic design automation (EDA) tools allowing engineers to manage the complexity of electronic circuits with transistor counts now reaching into the billions. Recently, we have been developing large-scale nonlinear photonic integrated logic circuits for next generation all-optical information processing. At this time a sufficiently powerful EDA-style software tool chain to design this type of complex circuits does not yet exist. Here we describe a hierarchical approach to automating the design and validation of photonic integrated circuits, which can scale to several orders of magnitude higher complexity than the state of the art. Most photonic integrated circuits developed today consist of a small number of components, and only limited hierarchy. For example, a simple photonic transceiver may contain on the order of 10 building-block components, consisting of grating couplers for photonic I/O, modulators, and signal splitters/combiners. Because this is relatively easy to lay out by hand (or simple script) existing photonic design tools have relatively little automation in comparison to electronics tools. But demonstrating all-optical logic will require significantly more complex photonic circuits containing up to 1,000 components, hence becoming infeasible to design manually. Our design framework is based off Python-based software from Luceda Photonics which provides an environment to describe components, simulate their behavior, and export design files (GDS) to foundries for fabrication. At a fundamental level, a photonic component is described as a parametric cell (PCell) similarly to electronics design. PCells are described by geometric characteristics of their layout. A critical part of the design framework is the implementation of PCells as Python objects. PCell objects can then use inheritance to simplify design, and hierarchical designs can be made by creating composite

  15. Optimized and Automated design of Plasma Diagnostics for Additive Manufacture

    Science.gov (United States)

    Stuber, James; Quinley, Morgan; Melnik, Paul; Sieck, Paul; Smith, Trevor; Chun, Katherine; Woodruff, Simon

    2016-10-01

    Despite having mature designs, diagnostics are usually custom designed for each experiment. Most of the design can be now be automated to reduce costs (engineering labor, and capital cost). We present results from scripted physics modeling and parametric engineering design for common optical and mechanical components found in many plasma diagnostics and outline the process for automated design optimization that employs scripts to communicate data from online forms through proprietary and open-source CAD and FE codes to provide a design that can be sent directly to a printer. As a demonstration of design automation, an optical beam dump, baffle and optical components are designed via an automated process and printed. Supported by DOE SBIR Grant DE-SC0011858.

  16. Derivation and validation of automated electronic search strategies to extract Charlson comorbidities from electronic medical records.

    Science.gov (United States)

    Singh, Balwinder; Singh, Amandeep; Ahmed, Adil; Wilson, Gregory A; Pickering, Brian W; Herasevich, Vitaly; Gajic, Ognjen; Li, Guangxi

    2012-09-01

    To develop and validate automated electronic note search strategies (automated digital algorithm) to identify Charlson comorbidities. The automated digital algorithm was built by a series of programmatic queries applied to an institutional electronic medical record database. The automated digital algorithm was derived from secondary analysis of an observational cohort study of 1447 patients admitted to the intensive care unit from January 1 through December 31, 2006, and validated in an independent cohort of 240 patients. The sensitivity, specificity, and positive and negative predictive values of the automated digital algorithm and International Classification of Diseases, Ninth Revision (ICD-9) codes were compared with comprehensive medical record review (reference standard) for the Charlson comorbidities. In the derivation cohort, the automated digital algorithm achieved a median sensitivity of 100% (range, 99%-100%) and a median specificity of 99.7% (range, 99%-100%). In the validation cohort, the sensitivity of the automated digital algorithm ranged from 91% to 100%, and the specificity ranged from 98% to 100%. The sensitivity of the ICD-9 codes ranged from 8% for dementia to 100% for leukemia, whereas specificity ranged from 86% for congestive heart failure to 100% for leukemia, dementia, and AIDS. Our results suggest that search strategies that use automated electronic search strategies to extract Charlson comorbidities from the clinical notes contained within the electronic medical record are feasible and reliable. Automated digital algorithm outperformed ICD-9 codes in all the Charlson variables except leukemia, with greater sensitivity, specificity, and positive and negative predictive values. Copyright © 2012 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  17. An Intelligent Automation Platform for Rapid Bioprocess Design.

    Science.gov (United States)

    Wu, Tianyi; Zhou, Yuhong

    2014-08-01

    Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user's inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. © 2013 Society for Laboratory Automation and Screening.

  18. Automated electronic medical record sepsis detection in the Emergency Department

    OpenAIRE

    Nguyen, Su; Mwakalindile, Edwin; Booth, James S.; Hogan, Vicki; Morgan, Jordan; Prickett, Charles T; Donnelly, John P.; Wang, Henry E.

    2014-01-01

    Background: While often first treated in the Emergency Department (ED), identification of sepsis is difficult. Electronic medical record (EMR) clinical decision tools offer a novel strategy for identifying patients with sepsis. The objective of this study was to test the accuracy of an EMR-based, automated sepsis identification system. Methods : We tested an EMR-based sepsis identification tool at a major academic, urban ED with 64,000 annual visits. The EMR system collected vital sign and la...

  19. Automated electronic medical record sepsis detection in the emergency department

    OpenAIRE

    Nguyen, Su Q.; Edwin Mwakalindile; Booth, James S.; Vicki Hogan; Jordan Morgan; Prickett, Charles T; Donnelly, John P.; Wang, Henry E.

    2014-01-01

    Background. While often first treated in the emergency department (ED), identification of sepsis is difficult. Electronic medical record (EMR) clinical decision tools offer a novel strategy for identifying patients with sepsis. The objective of this study was to test the accuracy of an EMR-based, automated sepsis identification system. Methods. We tested an EMR-based sepsis identification tool at a major academic, urban ED with 64,000 annual visits. The EMR system collected vital sign and lab...

  20. Development of design principles for automated systems in transport control.

    Science.gov (United States)

    Balfe, Nora; Wilson, John R; Sharples, Sarah; Clarke, Theresa

    2012-01-01

    This article reports the results of a qualitative study investigating attitudes towards and opinions of an advanced automation system currently used in UK rail signalling. In-depth interviews were held with 10 users, key issues associated with automation were identified and the automation's impact on the signalling task investigated. The interview data highlighted the importance of the signallers' understanding of the automation and their (in)ability to predict its outputs. The interviews also covered the methods used by signallers to interact with and control the automation, and the perceived effects on their workload. The results indicate that despite a generally low level of understanding and ability to predict the actions of the automation system, signallers have developed largely successful coping mechanisms that enable them to use the technology effectively. These findings, along with parallel work identifying desirable attributes of automation from the literature in the area, were used to develop 12 principles of automation which can be used to help design new systems which better facilitate cooperative working. The work reported in this article was completed with the active involvement of operational rail staff who regularly use automated systems in rail signalling. The outcomes are currently being used to inform decisions on the extent and type of automation and user interfaces in future generations of rail control systems.

  1. Model-Based approaches to Human-Automation Systems Design

    DEFF Research Database (Denmark)

    Jamieson, Greg A.; Andersson, Jonas; Bisantz, Ann

    2012-01-01

    Human-automation interaction in complex systems is common, yet design for this interaction is often conducted without explicit consideration of the role of the human operator. Fortunately, there are a number of modeling frameworks proposed for supporting this design activity. However...... (and reportedly one or two critics) can engage one another on several agreed questions about such frameworks. The goal is to aid non-aligned practitioners in choosing between alternative frameworks for their human-automation interaction design challenges....

  2. Design and Implementation of Company Tailored Automated Material Handling

    DEFF Research Database (Denmark)

    Langer, Gilad; Bilberg, Arne

    1996-01-01

    This article focuses on the problems of analysing automation of material handling systems in order to develop an efficient automated solution that is specifically tailored to the company. The research has resulted in development of new methods for evaluating factory automation from design...... investments in automation.The result of the research is a methodology for better selection of an AMH solution during production system development in an integrated development environment. The methodology is based on a framework yielding decision support by providing a set of guidelines and a method...... to implementation. The goals of the research were to analyse and evaluate automation in order to obtain an advantageous combination of human and automated resources. The idea is to asses different solutions in a virtual environment, where experiments and analyses can be performed so that the company can justify...

  3. EXADS - EXPERT SYSTEM FOR AUTOMATED DESIGN SYNTHESIS

    Science.gov (United States)

    Rogers, J. L.

    1994-01-01

    The expert system called EXADS was developed to aid users of the Automated Design Synthesis (ADS) general purpose optimization program. Because of the general purpose nature of ADS, it is difficult for a nonexpert to select the best choice of strategy, optimizer, and one-dimensional search options from the one hundred or so combinations that are available. EXADS aids engineers in determining the best combination based on their knowledge of the problem and the expert knowledge previously stored by experts who developed ADS. EXADS is a customized application of the AESOP artificial intelligence program (the general version of AESOP is available separately from COSMIC. The ADS program is also available from COSMIC.) The expert system consists of two main components. The knowledge base contains about 200 rules and is divided into three categories: constrained, unconstrained, and constrained treated as unconstrained. The EXADS inference engine is rule-based and makes decisions about a particular situation using hypotheses (potential solutions), rules, and answers to questions drawn from the rule base. EXADS is backward-chaining, that is, it works from hypothesis to facts. The rule base was compiled from sources such as literature searches, ADS documentation, and engineer surveys. EXADS will accept answers such as yes, no, maybe, likely, and don't know, or a certainty factor ranging from 0 to 10. When any hypothesis reaches a confidence level of 90% or more, it is deemed as the best choice and displayed to the user. If no hypothesis is confirmed, the user can examine explanations of why the hypotheses failed to reach the 90% level. The IBM PC version of EXADS is written in IQ-LISP for execution under DOS 2.0 or higher with a central memory requirement of approximately 512K of 8 bit bytes. This program was developed in 1986.

  4. An Intelligent Automation Platform for Rapid Bioprocess Design

    Science.gov (United States)

    Wu, Tianyi

    2014-01-01

    Bioprocess development is very labor intensive, requiring many experiments to characterize each unit operation in the process sequence to achieve product safety and process efficiency. Recent advances in microscale biochemical engineering have led to automated experimentation. A process design workflow is implemented sequentially in which (1) a liquid-handling system performs high-throughput wet lab experiments, (2) standalone analysis devices detect the data, and (3) specific software is used for data analysis and experiment design given the user’s inputs. We report an intelligent automation platform that integrates these three activities to enhance the efficiency of such a workflow. A multiagent intelligent architecture has been developed incorporating agent communication to perform the tasks automatically. The key contribution of this work is the automation of data analysis and experiment design and also the ability to generate scripts to run the experiments automatically, allowing the elimination of human involvement. A first-generation prototype has been established and demonstrated through lysozyme precipitation process design. All procedures in the case study have been fully automated through an intelligent automation platform. The realization of automated data analysis and experiment design, and automated script programming for experimental procedures has the potential to increase lab productivity. PMID:24088579

  5. Designing Domain-Specific HUMS Architectures: An Automated Approach

    Science.gov (United States)

    Mukkamala, Ravi; Agarwal, Neha; Kumar, Pramod; Sundaram, Parthiban

    2004-01-01

    The HUMS automation system automates the design of HUMS architectures. The automated design process involves selection of solutions from a large space of designs as well as pure synthesis of designs. Hence the whole objective is to efficiently search for or synthesize designs or parts of designs in the database and to integrate them to form the entire system design. The automation system adopts two approaches in order to produce the designs: (a) Bottom-up approach and (b) Top down approach. Both the approaches are endowed with a Suite of quantitative and quantitative techniques that enable a) the selection of matching component instances, b) the determination of design parameters, c) the evaluation of candidate designs at component-level and at system-level, d) the performance of cost-benefit analyses, e) the performance of trade-off analyses, etc. In short, the automation system attempts to capitalize on the knowledge developed from years of experience in engineering, system design and operation of the HUMS systems in order to economically produce the most optimal and domain-specific designs.

  6. Fundamentals of electronic systems design

    CERN Document Server

    Lienig, Jens

    2017-01-01

    This textbook covers the design of electronic systems from the ground up, from drawing and CAD essentials to recycling requirements. Chapter by chapter, it deals with the challenges any modern system designer faces: the design process and its fundamentals, such as technical drawings and CAD, electronic system levels, assembly and packaging issues and appliance protection classes, reliability analysis, thermal management and cooling, electromagnetic compatibility (EMC), all the way to recycling requirements and environmental-friendly design principles. Enables readers to face various challenges of designing electronic systems, including coverage from various engineering disciplines; Written to be accessible to readers of varying backgrounds; Uses illustrations extensively to reinforce fundamental concepts; Organized to follow essential design process, although chapters are self-contained and can be read in any order.

  7. Design and Development of an Integrated Workstation Automation Hub

    Energy Technology Data Exchange (ETDEWEB)

    Weber, Andrew; Ghatikar, Girish; Sartor, Dale; Lanzisera, Steven

    2015-03-30

    Miscellaneous Electronic Loads (MELs) account for one third of all electricity consumption in U.S. commercial buildings, and are drivers for a significant energy use in India. Many of the MEL-specific plug-load devices are concentrated at workstations in offices. The use of intelligence, and integrated controls and communications at the workstation for an Office Automation Hub – offers the opportunity to improve both energy efficiency and occupant comfort, along with services for Smart Grid operations. Software and hardware solutions are available from a wide array of vendors for the different components, but an integrated system with interoperable communications is yet to be developed and deployed. In this study, we propose system- and component-level specifications for the Office Automation Hub, their functions, and a prioritized list for the design of a proof-of-concept system. Leveraging the strength of both the U.S. and India technology sectors, this specification serves as a guide for researchers and industry in both countries to support the development, testing, and evaluation of a prototype product. Further evaluation of such integrated technologies for performance and cost is necessary to identify the potential to reduce energy consumptions in MELs and to improve occupant comfort.

  8. Automated Problem Domain Cognition Process in Information Systems Design

    OpenAIRE

    Loginov, Maxim; Mikov, Alexander

    2007-01-01

    An automated cognitive approach for the design of Information Systems is presented. It is supposed to be used at the very beginning of the design process, between the stages of requirements determination and analysis, including the stage of analysis. In the context of the approach used either UML or ERD notations may be used for model representation. The approach provides the opportunity of using natural language text documents as a source of knowledge for automated problem domain...

  9. TARDIS: An Automation Framework for JPL Mission Design and Navigation

    Science.gov (United States)

    Roundhill, Ian M.; Kelly, Richard M.

    2014-01-01

    Mission Design and Navigation at the Jet Propulsion Laboratory has implemented an automation framework tool to assist in orbit determination and maneuver design analysis. This paper describes the lessons learned from previous automation tools and how they have been implemented in this tool. In addition this tool has revealed challenges in software implementation, testing, and user education. This paper describes some of these challenges and invites others to share their experiences.

  10. Automated segmentation of molecular subunits in electron cryomicroscopy density maps.

    Science.gov (United States)

    Baker, Matthew L; Yu, Zeyun; Chiu, Wah; Bajaj, Chandrajit

    2006-12-01

    Electron cryomicroscopy (cryoEM) is capable of imaging large macromolecular machines composed of multiple components. However, it is currently only possible to achieve moderate resolution at which it may be possible to computationally extract the individual components in the machine. In this work, we present application details of an automated method for detecting and segmenting the components of a large machine in an experimentally determined density map. This method is applicable to object with and without symmetry and takes advantage of global and local symmetry axes if present. We have applied this segmentation algorithm to several cryoEM data sets already deposited in EMDB with various complexities, symmetries and resolutions and validated the results using manually segmented density and available structures of the components in the PDB. As such, automated segmentation could become a useful tool for the analysis of the ever-increasing number of structures of macromolecular machines derived from cryoEM.

  11. Automation of the electron-beam welding process

    Science.gov (United States)

    Koleva, E.; Dzharov, V.; Kardjiev, M.; Mladenov, G.

    2016-03-01

    In this work, the automatic control is considered of the vacuum and cooling systems of the located in the IE-BAS equipment for electron-beam welding, evaporation and surface modification. A project was elaborated for the control and management based on the development of an engineering support system using existing and additional technical means of automation. Optimization of the indicators, which are critical for the duration of reaching the working regime and stopping the operation of the installation, can be made using experimentally obtained transient characteristics. The automation of the available equipment aimed at improving its efficiency and the repeatability of the obtained results, as well as at stabilizing the process parameters, should be integrated in an Engineering Support System which, besides the operator supervision, consists of several subsystems for equipment control, data acquisition, information analysis, system management and decision-making support.

  12. Electronics reliability calculation and design

    CERN Document Server

    Dummer, Geoffrey W A; Hiller, N

    1966-01-01

    Electronics Reliability-Calculation and Design provides an introduction to the fundamental concepts of reliability. The increasing complexity of electronic equipment has made problems in designing and manufacturing a reliable product more and more difficult. Specific techniques have been developed that enable designers to integrate reliability into their products, and reliability has become a science in its own right. The book begins with a discussion of basic mathematical and statistical concepts, including arithmetic mean, frequency distribution, median and mode, scatter or dispersion of mea

  13. Architectures and design patterns for functional design of logic control and diagnostics in industrial automation

    OpenAIRE

    Sartini, Matteo

    2010-01-01

    Recently in most of the industrial automation process an ever increasing degree of automation has been observed. This increasing is motivated by the higher requirement of systems with great performance in terms of quality of products/services generated, productivity, efficiency and low costs in the design, realization and maintenance. This trend in the growth of complex automation systems is rapidly spreading over automated manufacturing systems (AMS), where the integration of the mechanic...

  14. Review of Automated Design and Optimization of MEMS

    DEFF Research Database (Denmark)

    Achiche, Sofiane; Fan, Zhun; Bolognini, Francesca

    2007-01-01

    In recent years MEMS saw a very rapid development. Although many advances have been reached, due to the multiphysics nature of MEMS, their design is still a difficult task carried on mainly by hand calculation. In order to help to overtake such difficulties, attempts to automate MEMS design were...... carried out. This paper presents a review of these techniques. The design task of MEMS is usually divided into four main stages: System Level, Device Level, Physical Level and the Process Level. The state of the art o automated MEMS design in each of these levels is investigated....

  15. Design and fabrication of an automated temperature programmed ...

    Indian Academy of Sciences (India)

    Unknown

    *For correspondence. Design and fabrication of an automated temperature programmed reaction system to evaluate 3-way catalysts ... Since the design of the first desorption system by Cvetonovic and Amenomiya,1 .... tored by a software program through PC via RS232 interface. Typical heating rates range from 5°C min–1.

  16. PROJECT ENGINEERING DATA MANAGEMENT AT AUTOMATED PREPARATION OF DESIGN DOCUMENTATION

    Directory of Open Access Journals (Sweden)

    A. V. Guryanov

    2017-01-01

    Full Text Available We have developed and realized instrumental means for automated support of end-to-end design process for design documentation on a product at the programming level. The proposed decision is based on processing of the engineering project data that are contained in interdependent design documents: tactical technical characteristics of products, data on the valuable metals contained in them, the list of components applied in a product and others. Processing of engineering data is based on their conversion to the form provided by requirements of industry standards for design documentation preparation. The general graph of the design documentation developed on a product is provided. The description of the developed software product is given. Automated preparation process of interdependent design documents is shown on the example of preparation of purchased products list. Results of work can be used in case of research and development activities on creation of perspective samples of ADP equipment.

  17. A Case Study in CAD Design Automation

    Science.gov (United States)

    Lowe, Andrew G.; Hartman, Nathan W.

    2011-01-01

    Computer-aided design (CAD) software and other product life-cycle management (PLM) tools have become ubiquitous in industry during the past 20 years. Over this time they have continuously evolved, becoming programs with enormous capabilities, but the companies that use them have not evolved their design practices at the same rate. Due to the…

  18. PROJECT ENGINEERING DATA MANAGEMENT AT AUTOMATED PREPARATION OF DESIGN DOCUMENTATION

    OpenAIRE

    A. V. Guryanov; A. V. Shukalov; I. O. Zharinov; S. A. Leonovets; E. Y. Didenko

    2017-01-01

    We have developed and realized instrumental means for automated support of end-to-end design process for design documentation on a product at the programming level. The proposed decision is based on processing of the engineering project data that are contained in interdependent design documents: tactical technical characteristics of products, data on the valuable metals contained in them, the list of components applied in a product and others. Processing of engineering data is based on their ...

  19. Universal electronics for miniature and automated chemical assays.

    Science.gov (United States)

    Urban, Pawel L

    2015-02-21

    This minireview discusses universal electronic modules (generic programmable units) and their use by analytical chemists to construct inexpensive, miniature or automated devices. Recently, open-source platforms have gained considerable popularity among tech-savvy chemists because their implementation often does not require expert knowledge and investment of funds. Thus, chemistry students and researchers can easily start implementing them after a few hours of reading tutorials and trial-and-error. Single-board microcontrollers and micro-computers such as Arduino, Teensy, Raspberry Pi or BeagleBone enable collecting experimental data with high precision as well as efficient control of electric potentials and actuation of mechanical systems. They are readily programmed using high-level languages, such as C, C++, JavaScript or Python. They can also be coupled with mobile consumer electronics, including smartphones as well as teleinformatic networks. More demanding analytical tasks require fast signal processing. Field-programmable gate arrays enable efficient and inexpensive prototyping of high-performance analytical platforms, thus becoming increasingly popular among analytical chemists. This minireview discusses the advantages and drawbacks of universal electronic modules, considering their application in prototyping and manufacture of intelligent analytical instrumentation.

  20. Automating expert role to determine design concept in Kansei Engineering

    Science.gov (United States)

    Lokman, Anitawati Mohd; Haron, Mohammad Bakri Che; Abidin, Siti Zaleha Zainal; Khalid, Noor Elaiza Abd

    2016-02-01

    Affect has become imperative in product quality. In affective design field, Kansei Engineering (KE) has been recognized as a technology that enables discovery of consumer's emotion and formulation of guide to design products that win consumers in the competitive market. Albeit powerful technology, there is no rule of thumb in its analysis and interpretation process. KE expertise is required to determine sets of related Kansei and the significant concept of emotion. Many research endeavors become handicapped with the limited number of available and accessible KE experts. This work is performed to simulate the role of experts with the use of Natphoric algorithm thus providing sound solution to the complexity and flexibility in KE. The algorithm is designed to learn the process by implementing training datasets taken from previous KE research works. A framework for automated KE is then designed to realize the development of automated KE system. A comparative analysis is performed to determine feasibility of the developed prototype to automate the process. The result shows that the significant Kansei is determined by manual KE implementation and the automated process is highly similar. KE research advocates will benefit this system to automatically determine significant design concepts.

  1. Towards Automated Design, Analysis and Optimization of Declarative Curation Workflows

    Directory of Open Access Journals (Sweden)

    Tianhong Song

    2014-10-01

    Full Text Available Data curation is increasingly important. Our previous work on a Kepler curation package has demonstrated advantages that come from automating data curation pipelines by using workflow systems. However, manually designed curation workflows can be error-prone and inefficient due to a lack of user understanding of the workflow system, misuse of actors, or human error. Correcting problematic workflows is often very time-consuming. A more proactive workflow system can help users avoid such pitfalls. For example, static analysis before execution can be used to detect the potential problems in a workflow and help the user to improve workflow design. In this paper, we propose a declarative workflow approach that supports semi-automated workflow design, analysis and optimization. We show how the workflow design engine helps users to construct data curation workflows, how the workflow analysis engine detects different design problems of workflows and how workflows can be optimized by exploiting parallelism.

  2. Preliminary Design of an Automated White Board Cleaner

    African Journals Online (AJOL)

    Toshiba

    Abstract. The work presented in this paper is on the preliminary design and fabrication of an automated whiteboard cleaner. The objective here in is to reduce the man-power involved in cleaning white boards after use. Though the use of smart boards is increasing, many institutions in the developed and developing world ...

  3. Design a Persian Automated Plagiarism Detector (AMZPPD)

    OpenAIRE

    Mahmoodi, Maryam; Varnamkhasti, Mohammad Mahmoodi

    2014-01-01

    Currently there are lots of plagiarism detection approaches. But few of them implemented and adapted for Persian languages. In this paper, our work on designing and implementation of a plagiarism detection system based on pre-processing and NLP technics will be described. And the results of testing on a corpus will be presented.

  4. Library Automation Design for Visually Impaired People

    Science.gov (United States)

    Yurtay, Nilufer; Bicil, Yucel; Celebi, Sait; Cit, Guluzar; Dural, Deniz

    2011-01-01

    Speech synthesis is a technology used in many different areas in computer science. This technology can bring a solution to reading activity of visually impaired people due to its text to speech conversion. Based on this problem, in this study, a system is designed needed for a visually impaired person to make use of all the library facilities in…

  5. Automated Work Package: Conceptual Design and Data Architecture

    Energy Technology Data Exchange (ETDEWEB)

    Al Rashdan, Ahmad [Idaho National Lab. (INL), Idaho Falls, ID (United States); Oxstrand, Johanna [Idaho National Lab. (INL), Idaho Falls, ID (United States); Agarwal, Vivek [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-05-26

    The automated work package (AWP) is one of the U.S. Department of Energy’s (DOE) Light Water Reactor Sustainability Program efforts to enhance the safety and economics of the nuclear power industry. An AWP is an adaptive and interactive work package that intelligently drives the work process according to the plant condition, resources status, and users progress. The AWP aims to automate several manual tasks of the work process to enhance human performance and reduce human errors. Electronic work packages (eWPs), studied by the Electric Power Research Institute (EPRI), are work packages that rely to various extent on electronic data processing and presentation. AWPs are the future of eWPs. They are envisioned to incorporate the advanced technologies of the future, and thus address the unresolved deficiencies associated with the eWPs in a nuclear power plant. In order to define the AWP, it is necessary to develop an ideal envisioned scenario of the future work process without any current technology restriction. The approach followed to develop this scenario is specific to every stage of the work process execution. The scenario development resulted in fifty advanced functionalities that can be part of the AWP. To rank the importance of these functionalities, a survey was conducted involving several U.S. nuclear utilities. The survey aimed at determining the current need of the nuclear industry with respect to the current work process, i.e. what the industry is satisfied with, and where the industry envisions potential for improvement. The survey evaluated the most promising functionalities resulting from the scenario development. The results demonstrated a significant desire to adopt the majority of these functionalities. The results of the survey are expected to drive the Idaho National Laboratory (INL) AWP research and development (R&D). In order to facilitate this mission, a prototype AWP is needed. Since the vast majority of earlier efforts focused on the

  6. Automated design of complex dynamic systems.

    Directory of Open Access Journals (Sweden)

    Michiel Hermans

    Full Text Available Several fields of study are concerned with uniting the concept of computation with that of the design of physical systems. For example, a recent trend in robotics is to design robots in such a way that they require a minimal control effort. Another example is found in the domain of photonics, where recent efforts try to benefit directly from the complex nonlinear dynamics to achieve more efficient signal processing. The underlying goal of these and similar research efforts is to internalize a large part of the necessary computations within the physical system itself by exploiting its inherent non-linear dynamics. This, however, often requires the optimization of large numbers of system parameters, related to both the system's structure as well as its material properties. In addition, many of these parameters are subject to fabrication variability or to variations through time. In this paper we apply a machine learning algorithm to optimize physical dynamic systems. We show that such algorithms, which are normally applied on abstract computational entities, can be extended to the field of differential equations and used to optimize an associated set of parameters which determine their behavior. We show that machine learning training methodologies are highly useful in designing robust systems, and we provide a set of both simple and complex examples using models of physical dynamical systems. Interestingly, the derived optimization method is intimately related to direct collocation a method known in the field of optimal control. Our work suggests that the application domains of both machine learning and optimal control have a largely unexplored overlapping area which envelopes a novel design methodology of smart and highly complex physical systems.

  7. Designing High Performance Factory Automation Applications on Top of DDS

    Directory of Open Access Journals (Sweden)

    Isidro Calvo

    2013-04-01

    Full Text Available DDS is a recent specification aimed at providing high-performance publisher/subscriber middleware solutions. Despite being a very powerful flexible technology, it may prove complex to use, especially for the inexperienced. This work provides some guidelines for connecting software components that represent a new generation of automation devices (such as PLCs, IPCs and robots using Data Distribution Service (DDS as a virtual software bus. More specifically, it presents the design of a DDS-based component, the so-called Automation Component, and discusses how to map different traffic patterns using DDS entities exploiting the wealth of QoS management mechanisms provided by the DDS specification. A case study demonstrates the creation of factory automation applications out of software components that encapsulate independent stations.

  8. Automated hierarchical testable design of digital circuits

    Science.gov (United States)

    Kraak, M.

    1993-03-01

    The thesis gives an overview of approaches dealing with the selection of test strategies and methods for digital circuits and the incorporation of test in designs. A review is provided of existing testability analyzers. A new way to analyze testability at three hierarchical levels of abstraction is presented. It is shown how this approach is contained in an expert system rule-base called TRI Stage Testability Analysis (TRISTAN). The paper then deals with testability synthesis. It is shown that a new synthesis method had to be devised to be able to hierarchically select test strategies and methods. The testability synthesizer is also contained in a rule-base, called Intelligent Synthesis of Testable Designs (ISOLDE). TRISTAN and ISOLDE are parts of an expert system called WAGNER. The knowledge processor for WAGNER is covered, presenting its knowledge representation scheme, knowledge acquisition and inference mechanism. Results of experiments done with WAGNER on board and chip level designs are given. Conclusive remarks provide an outlook to continued research.

  9. Nanocluster technologies for electronics design

    CERN Document Server

    Parker, A J

    2001-01-01

    based electronic systems. The work presented in this thesis covers an investigation into the use of metal nanoclusters in nanoelectronics design. Initial studies explored the interactions of the dodecanethiol passivated gold nanocluster, held in solution with toluene, and the native oxide covered silicon surface. Deposition of the clusters is achieved by pippetting mu-litre quantities of the solution onto the surface, and allowing the solvent to evaporate leaving the clusters as residue. Patterning of the surface with micron scale photoresist structures prior to cluster exposure, led to the selective aggregation of cluster deposits along the resist boundaries. An extension of this technique, examined the flow of the cluster solution along photoresist structures which extended beyond the solution droplet. Investigation into the electronic properties of nanocluster arrays generated non-linear current-voltage curves, which are explained in terms of two very simple models. These results cast doubt over the suitab...

  10. Analog integrated circuit design automation placement, routing and parasitic extraction techniques

    CERN Document Server

    Martins, Ricardo; Horta, Nuno

    2017-01-01

    This book introduces readers to a variety of tools for analog layout design automation. After discussing the placement and routing problem in electronic design automation (EDA), the authors overview a variety of automatic layout generation tools, as well as the most recent advances in analog layout-aware circuit sizing. The discussion includes different methods for automatic placement (a template-based Placer and an optimization-based Placer), a fully-automatic Router and an empirical-based Parasitic Extractor. The concepts and algorithms of all the modules are thoroughly described, enabling readers to reproduce the methodologies, improve the quality of their designs, or use them as starting point for a new tool. All the methods described are applied to practical examples for a 130nm design process, as well as placement and routing benchmark sets. Introduces readers to hierarchical combination of Pareto fronts of placements; Presents electromigration-aware routing with multilayer multiport terminal structures...

  11. Computer-automated tuning of semiconductor double quantum dots into the single-electron regime

    Energy Technology Data Exchange (ETDEWEB)

    Baart, T. A.; Vandersypen, L. M. K. [QuTech, Delft University of Technology, P.O. Box 5046, 2600 GA Delft (Netherlands); Kavli Institute of Nanoscience, Delft University of Technology, P.O. Box 5046, 2600 GA Delft (Netherlands); Eendebak, P. T. [QuTech, Delft University of Technology, P.O. Box 5046, 2600 GA Delft (Netherlands); Netherlands Organisation for Applied Scientific Research (TNO), P.O. Box 155, 2600 AD Delft (Netherlands); Reichl, C.; Wegscheider, W. [Solid State Physics Laboratory, ETH Zürich, 8093 Zürich (Switzerland)

    2016-05-23

    We report the computer-automated tuning of gate-defined semiconductor double quantum dots in GaAs heterostructures. We benchmark the algorithm by creating three double quantum dots inside a linear array of four quantum dots. The algorithm sets the correct gate voltages for all the gates to tune the double quantum dots into the single-electron regime. The algorithm only requires (1) prior knowledge of the gate design and (2) the pinch-off value of the single gate T that is shared by all the quantum dots. This work significantly alleviates the user effort required to tune multiple quantum dot devices.

  12. Automated Design Framework for Synthetic Biology Exploiting Pareto Optimality.

    Science.gov (United States)

    Otero-Muras, Irene; Banga, Julio R

    2017-07-21

    In this work we consider Pareto optimality for automated design in synthetic biology. We present a generalized framework based on a mixed-integer dynamic optimization formulation that, given design specifications, allows the computation of Pareto optimal sets of designs, that is, the set of best trade-offs for the metrics of interest. We show how this framework can be used for (i) forward design, that is, finding the Pareto optimal set of synthetic designs for implementation, and (ii) reverse design, that is, analyzing and inferring motifs and/or design principles of gene regulatory networks from the Pareto set of optimal circuits. Finally, we illustrate the capabilities and performance of this framework considering four case studies. In the first problem we consider the forward design of an oscillator. In the remaining problems, we illustrate how to apply the reverse design approach to find motifs for stripe formation, rapid adaption, and fold-change detection, respectively.

  13. An automated approach to the design of decision tree classifiers

    Science.gov (United States)

    Argentiero, P.; Chin, R.; Beaudet, P.

    1982-01-01

    An automated technique is presented for designing effective decision tree classifiers predicated only on a priori class statistics. The procedure relies on linear feature extractions and Bayes table look-up decision rules. Associated error matrices are computed and utilized to provide an optimal design of the decision tree at each so-called 'node'. A by-product of this procedure is a simple algorithm for computing the global probability of correct classification assuming the statistical independence of the decision rules. Attention is given to a more precise definition of decision tree classification, the mathematical details on the technique for automated decision tree design, and an example of a simple application of the procedure using class statistics acquired from an actual Landsat scene.

  14. An automated methodology development. [software design for combat simulation

    Science.gov (United States)

    Hawley, L. R.

    1985-01-01

    The design methodology employed in testing the applicability of Ada in large-scale combat simulations is described. Ada was considered as a substitute for FORTRAN to lower life cycle costs and ease the program development efforts. An object-oriented approach was taken, which featured definitions of military targets, the capability of manipulating their condition in real-time, and one-to-one correlation between the object states and real world states. The simulation design process was automated by the problem statement language (PSL)/problem statement analyzer (PSA). The PSL/PSA system accessed the problem data base directly to enhance the code efficiency by, e.g., eliminating non-used subroutines, and provided for automated report generation, besides allowing for functional and interface descriptions. The ways in which the methodology satisfied the responsiveness, reliability, transportability, modifiability, timeliness and efficiency goals are discussed.

  15. Verification of the thermal design of electronic equipment

    Energy Technology Data Exchange (ETDEWEB)

    Hienonen, R.; Karjalainen, M.; Lankinen, R. [VTT Automation, Espoo (Finland). ProTechno

    1997-12-31

    The project `Verification of the thermal design of electronic equipment` studied the methodology to be followed in the verification of thermal design of electronic equipment. This project forms part of the `Cool Electronics` research programme funded by TEKES, the Finnish Technology Development Centre. This project was carried out jointly by VTT Automation, Lappeenranta University of Technology, Nokia Research Center and ABB Industry Oy VSD-Technology. The thermal design of electronic equipment has a significant impact on the cost, reliability, tolerance to different environments, selection of components and materials, and ergonomics of the product. This report describes the method for verification of thermal design. It assesses the goals set for thermal design, environmental requirements, technical implementation of the design, thermal simulation and modelling, and design qualification testing and the measurements needed. The verification method covers all packaging levels of electronic equipment from the system level to the electronic component level. The method described in this report can be used as part of the quality system of a corporation. The report includes information about the measurement and test methods needed in the verification process. Some measurement methods for the temperature, flow and pressure of air are described. (orig.) Published in Finnish VTT Julkaisuja 824. 22 refs.

  16. Magnetization-prepared shells trajectory with automated gradient waveform design.

    Science.gov (United States)

    Shu, Yunhong; Tao, Shengzhen; Trzasko, Joshua D; Huston, John; Weavers, Paul T; Bernstein, Matt A

    2017-08-21

    To develop a fully automated trajectory and gradient waveform design for the non-Cartesian shells acquisition, and to develop a magnetization-prepared (MP) shells acquisition to achieve an efficient three-dimensional acquisition with improved gray-to-white brain matter contrast. After reviewing the shells k-space trajectory, a novel, fully automated trajectory design is developed that allows for gradient waveforms to be automatically generated for specified acquisition parameters. Designs for two types of shells are introduced, including fully sampled and undersampled/accelerated shells. Using those designs, an MP-Shells acquisition is developed by adjusting the acquisition order of shells interleaves to synchronize the center of k-space sampling with the peak of desired gray-to-white matter contrast. The feasibility of the proposed design and MP-Shells is demonstrated using simulation, phantom, and volunteer subject experiments, and the performance of MP-Shells is compared with a clinical Cartesian magnetization-prepared rapid gradient echo acquisition. Initial experiments show that MP-Shells produces excellent image quality with higher data acquisition efficiency and improved gray-to-white matter contrast-to-noise ratio (by 36%) compared with the conventional Cartesian magnetization-prepared rapid gradient echo acquisition. We demonstrated the feasibility of a three-dimensional MP-Shells acquisition and an automated trajectory design to achieve an efficient acquisition with improved gray-to-white matter contrast. Magn Reson Med, 2017. © 2017 International Society for Magnetic Resonance in Medicine. © 2017 International Society for Magnetic Resonance in Medicine.

  17. Electronic Alerts with Automated Consultations Promote Appropriate Antimicrobial Prescriptions.

    Directory of Open Access Journals (Sweden)

    Moonsuk Kim

    Full Text Available To promote appropriate antimicrobial use in bloodstream infections (BSIs, we initiated an intervention program consisting of electronic alerts and automated infectious diseases consultations in which the identification and antimicrobial susceptibility test (ID/AST results were reported.We compared the appropriateness of antimicrobial prescriptions and clinical outcomes in BSIs before and after initiation of the program. Appropriateness was assessed in terms of effective therapy, optimal therapy, de-escalation therapy, and intravenous to oral switch therapy.There were 648 BSI episodes in the pre-program period and 678 in the program period. The proportion of effective, optimal, and de-escalation therapies assessed 24 hours after the reporting of the ID/AST results increased from 87.8% (95% confidence interval [CI] 85.5-90.5, 64.4% (95% CI 60.8-68.1, and 10.0% (95% CI 7.5-12.6 in the pre-program period, respectively, to 94.4% (95% CI 92.7-96.1, 81.4% (95% CI 78.4-84.3, and 18.6% (95% CI 15.3-21.9 in the program period, respectively. Kaplan-Meier analyses and log-rank tests revealed that the time to effective (p<0.001, optimal (p<0.001, and de-escalation (p = 0.017 therapies were significantly different in the two periods. Segmented linear regression analysis showed the increase in the proportion of effective (p = 0.015, optimal (p<0.001, and de-escalation (p = 0.010 therapies at 24 hours after reporting, immediately after program initiation. No significant baseline trends or changes in trends were identified. There were no significant differences in time to intravenous to oral switch therapy, length of stay, and 30-day mortality rate.This novel form of stewardship program based on intervention by infectious disease specialists and information technology improved antimicrobial prescriptions in BSIs.

  18. Automated platform for designing multiple robot work cells

    Science.gov (United States)

    Osman, N. S.; Rahman, M. A. A.; Rahman, A. A. Abdul; Kamsani, S. H.; Bali Mohamad, B. M.; Mohamad, E.; Zaini, Z. A.; Rahman, M. F. Ab; Mohamad Hatta, M. N. H.

    2017-06-01

    Designing the multiple robot work cells is very knowledge-intensive, intricate, and time-consuming process. This paper elaborates the development process of a computer-aided design program for generating the multiple robot work cells which offer a user-friendly interface. The primary purpose of this work is to provide a fast and easy platform for less cost and human involvement with minimum trial and errors adjustments. The automated platform is constructed based on the variant-shaped configuration concept with its mathematical model. A robot work cell layout, system components, and construction procedure of the automated platform are discussed in this paper where integration of these items will be able to automatically provide the optimum robot work cell design according to the information set by the user. This system is implemented on top of CATIA V5 software and utilises its Part Design, Assembly Design, and Macro tool. The current outcomes of this work provide a basis for future investigation in developing a flexible configuration system for the multiple robot work cells.

  19. Xyce parallel electronic simulator design.

    Energy Technology Data Exchange (ETDEWEB)

    Thornquist, Heidi K.; Rankin, Eric Lamont; Mei, Ting; Schiek, Richard Louis; Keiter, Eric Richard; Russo, Thomas V.

    2010-09-01

    This document is the Xyce Circuit Simulator developer guide. Xyce has been designed from the 'ground up' to be a SPICE-compatible, distributed memory parallel circuit simulator. While it is in many respects a research code, Xyce is intended to be a production simulator. As such, having software quality engineering (SQE) procedures in place to insure a high level of code quality and robustness are essential. Version control, issue tracking customer support, C++ style guildlines and the Xyce release process are all described. The Xyce Parallel Electronic Simulator has been under development at Sandia since 1999. Historically, Xyce has mostly been funded by ASC, the original focus of Xyce development has primarily been related to circuits for nuclear weapons. However, this has not been the only focus and it is expected that the project will diversify. Like many ASC projects, Xyce is a group development effort, which involves a number of researchers, engineers, scientists, mathmaticians and computer scientists. In addition to diversity of background, it is to be expected on long term projects for there to be a certain amount of staff turnover, as people move on to different projects. As a result, it is very important that the project maintain high software quality standards. The point of this document is to formally document a number of the software quality practices followed by the Xyce team in one place. Also, it is hoped that this document will be a good source of information for new developers.

  20. Automated Design Technique of Al-Alloys Extrusion Die Set

    Directory of Open Access Journals (Sweden)

    I. S. Kniazkin

    2015-01-01

    Full Text Available CAD-designers of aluminum extrusion die set have to make many decisions on tooling type, construction etc. by experience, their own metal flow sense and special methods of tooling design produced by manufacturer. There was created some software products for designing the planar die set. In addition, metal flow simulation programs using three-dimensional die set models as initial data were developed.However, it is a difficult task to create a high-quality solid die set model from scratch shortly. This led to three-dimensional die set parametrization systems development. QForm Extrusion Die Designer is one of them. Based on QExDD the automated design technique of die set elements is proposed. It takes into consideration the volumetric metal flow factor and design experience. In addition, it is aimed at CAD-CAE connection with QForm-Extrusion program.The proposed technique consists of two stages: preliminary designing and correction cycle. The first stage is to prepare profile contour and choose the first die set construction version. The algorithms implemented at this stage use only geometrical data, particularly profile contour. A received three-dimensional die set model is transferred to the second stage for iterative construction modification based on extrusion simulation results. As a result of automated design process there is the die set parametrical model that is ready for production and further extrusion test.The first version of the proposed technique is implemented using the QExDD software program and is now under tests in companies of Russia and UK.

  1. Electronic Resource Management and Design

    Science.gov (United States)

    Abrams, Kimberly R.

    2015-01-01

    We have now reached a tipping point at which electronic resources comprise more than half of academic library budgets. Because of the increasing work associated with the ever-increasing number of e-resources, there is a trend to distribute work throughout the library even in the presence of an electronic resources department. In 2013, the author…

  2. Automated determination of crystal orientations from electron backscattering patterns

    DEFF Research Database (Denmark)

    Lassen, Niels Christian Krieger

    1994-01-01

    The electron backscattering pattern (EBSP) technique is widely accepted as being an extremely powerful tool for measuring the crystallographic orientation of individual crystallites in polycrystalline materials. Procedures which allow crystal orientations to be calculated on the bases of the posi......The electron backscattering pattern (EBSP) technique is widely accepted as being an extremely powerful tool for measuring the crystallographic orientation of individual crystallites in polycrystalline materials. Procedures which allow crystal orientations to be calculated on the bases...... be collected by this method. This thesis describes the development and implementation of a system which enables crystallographic orientations to be obtained fully automatically through the use of computerized analysis and interpretation of EBSPs. More specifically, this thesis will describe the design...... determination of crystallographic orientations from EBSPs is accurate knowledge of three calibration parameters which describe the position of the point from which the patterns are emitted relative to the phosphor screen on which they are recorded. This thesis will describe a novel method by which...

  3. Automated disease cohort selection using word embeddings from Electronic Health Records.

    Science.gov (United States)

    Glicksberg, Benjamin S; Miotto, Riccardo; Johnson, Kipp W; Shameer, Khader; Li, Li; Chen, Rong; Dudley, Joel T

    2018-01-01

    Accurate and robust cohort definition is critical to biomedical discovery using Electronic Health Records (EHR). Similar to prospective study designs, high quality EHR-based research requires rigorous selection criteria to designate case/control status particular to each disease. Electronic phenotyping algorithms, which are manually built and validated per disease, have been successful in filling this need. However, these approaches are time-consuming, leading to only a relatively small amount of algorithms for diseases developed. Methodologies that automatically learn features from EHRs have been used for cohort selection as well. To date, however, there has been no systematic analysis of how these methods perform against current gold standards. Accordingly, this paper compares the performance of a state-of-the-art automated feature learning method to extracting research-grade cohorts for five diseases against their established electronic phenotyping algorithms. In particular, we use word2vec to create unsupervised embeddings of the phenotype space within an EHR system. Using medical concepts as a query, we then rank patients by their proximity in the embedding space and automatically extract putative disease cohorts via a distance threshold. Experimental evaluation shows promising results with average F-score of 0.57 and AUC-ROC of 0.98. However, we noticed that results varied considerably between diseases, thus necessitating further investigation and/or phenotype-specific refinement of the approach before being readily deployed across all diseases.

  4. Automating Vector Autoregression on Electronic Patient Diary Data

    NARCIS (Netherlands)

    Emerencia, Ando Celino; van der Krieke, Lian; Bos, Elisabeth H.; de Jonge, Peter; Petkov, Nicolai; Aiello, Marco

    Finding the best vector autoregression model for any dataset, medical or otherwise, is a process that, to this day, is frequently performed manually in an iterative manner requiring a statistical expertize and time. Very few software solutions for automating this process exist, and they still

  5. Low Energy Electronics Design for Mobile Platforms

    National Research Council Canada - National Science Library

    East, J

    2002-01-01

    In order to address the need for low-energy electronics design for mobile platforms in future Army communication systems a multidisciplinary effort is needed to investigate system and component design...

  6. Iterative User Interface Design for Automated Sequential Organ Failure Assessment Score Calculator in Sepsis Detection.

    Science.gov (United States)

    Aakre, Christopher Ansel; Kitson, Jaben E; Li, Man; Herasevich, Vitaly

    2017-05-18

    The new sepsis definition has increased the need for frequent sequential organ failure assessment (SOFA) score recalculation and the clerical burden of information retrieval makes this score ideal for automated calculation. The aim of this study was to (1) estimate the clerical workload of manual SOFA score calculation through a time-motion analysis and (2) describe a user-centered design process for an electronic medical record (EMR) integrated, automated SOFA score calculator with subsequent usability evaluation study. First, we performed a time-motion analysis by recording time-to-task-completion for the manual calculation of 35 baseline and 35 current SOFA scores by 14 internal medicine residents over a 2-month period. Next, we used an agile development process to create a user interface for a previously developed automated SOFA score calculator. The final user interface usability was evaluated by clinician end users with the Computer Systems Usability Questionnaire. The overall mean (standard deviation, SD) time-to-complete manual SOFA score calculation time was 61.6 s (33). Among the 24% (12/50) usability survey respondents, our user-centered user interface design process resulted in >75% favorability of survey items in the domains of system usability, information quality, and interface quality. Early stakeholder engagement in our agile design process resulted in a user interface for an automated SOFA score calculator that reduced clinician workload and met clinicians' needs at the point of care. Emerging interoperable platforms may facilitate dissemination of similarly useful clinical score calculators and decision support algorithms as "apps." A user-centered design process and usability evaluation should be considered during creation of these tools.

  7. Using a Functional Architecture to Identify Human-Automation Trust Needs and Design Requirements

    Science.gov (United States)

    2016-12-01

    example, Parasuraman cites a study performed by Muir (1988) on the use of an automated aid to control a simulated beverage manufacturing plant (1997, 236...Distribution is unlimited. USING A FUNCTIONAL ARCHITECTURE TO IDENTIFY HUMAN- AUTOMATION TRUST NEEDS AND DESIGN REQUIREMENTS Bradley A...1  B.  OVERVIEW OF AUTOMATION USE ..................................................2  C.  RESEARCH OBJECTIVE

  8. 76 FR 27606 - Technical Corrections To Remove Obsolete References to Non-Automated Carriers From Electronic...

    Science.gov (United States)

    2011-05-12

    ... Non- Automated Carriers From Electronic Cargo Manifest Regulations and to Update Terminology AGENCY... amends the U.S. Customs and Border Protection (CBP) regulations concerning the ] mandatory electronic...). When CBP amended its regulations to implement section 343(a) of the Trade Act of 2002 to require...

  9. AUTOMATED IRRIGATION SYSTEM CONSTITUTED OF ELECTRONIC ELEMENTS, MOBILE DEVICE AND THE CONSTRUCTION OF SPRINKLER

    Directory of Open Access Journals (Sweden)

    Alma Delia González

    2017-12-01

    Full Text Available This document presents the development of an automated irrigation system, which consisted of a sprinkler that has a range of 16 meters in diameter using only sprinklers per one hectare of land, water pump, hose, water containers, electro valves, relays, electronic components such as humidity and temperature sensor, ultrasonic sensor, LCD screen, microcontroller (Arduino Mega, for communication a bluetooth module and a mobile device (Android. The agile methodology used was Extreme XP Programming, following its 4 phases, planning, design, development and testing. With this an automated irrigation system was used that was developed to monitor temperature, humidity and to generate a saving in the water thanks to the census of the container of the same, as well as the reduction of maintenance costs, this can be activated or deactivated by the user regardless of the conditions. The system complies with the characteristics of a utility model, because these models are all those objects, tools, appliances or tools that, as a result of a change in their layout, configuration, structure or form, present a different function with respect to the parts that integrate it or advantages in terms of its usefulness and thanks to the search carried out in IMPI. In the study of the state of the art the search was made in the data bases of Mexico in SIGA (Information System of the Gazette of the Industrial Property and internationally in Thomson, the results showed that there were similar sy

  10. Automated Design of Restraint Layer of an Inflatable Vessel

    Science.gov (United States)

    Spexarth, Gary

    2007-01-01

    A Mathcad computer program largely automates the design and analysis of the restraint layer (the primary load-bearing layer) of an inflatable vessel that consists of one or more sections having cylindrical, toroidal, and/or spherical shape(s). A restraint layer typically comprises webbing in the form of multiple straps. The design task includes choosing indexing locations along the straps, computing the load at every location in each strap, computing the resulting stretch at each location, and computing the amount of undersizing required of each strap so that, once the vessel is inflated and the straps thus stretched, the vessel can be expected to assume the desired shape. Prior to the development of this program, the design task was performed by use of a difficult-to-use spreadsheet program that required manual addition of rows and columns depending on the numbers of strap rows and columns of a given design. In contrast, this program is completely parametric and includes logic that automatically adds or deletes rows and columns as needed. With minimal input from the user, this program automatically computes indexing locations, strap lengths, undersizing requirements, and all design data required to produce detailed drawings and assembly procedures. It also generates textual comments that help the user understand the calculations.

  11. The Automated Bicron Tester: Automated electronic instrument diagnostic, testing, and alignment system with records generation

    Energy Technology Data Exchange (ETDEWEB)

    Rao, G.S.; Maddox, S.R.; Turner, G.W.; Vandermolen, R.I.

    1995-11-01

    The Bicron Surveyor MX is a portable radiation monitoring instrument used by the Office of Radiation Protection at Oak Ridge National Laboratory. This instrument must be calibrated in order to assure reliable operation. A manual calibration procedure was developed, but it was time consuming and repetitive. Therefore, an automated tester station that would allow the technicians to calibrate the instruments faster and more reliably was developed. With the automated tester station, calibration records and accountability could be generated and maintained automatically. This allows the technicians to concentrate on repairing defective units. The Automated Bicron Tester consists of an operator interface, an analog board, and a digital controller board. The panel is the user interface that allows the technician to communicate with the tester. The analog board has an analog-to-digital converter (ADC) that converts the signals from the instrument into digital data that the tester can manipulate. The digital controller board contains the circuitry to perform the test and to communicate the results to the host personal computer (PC). The tester station is connected to the unit under test through a special test harness that attaches to a header on the Bicron. The tester sends pulse trains to the Bicron and measures the resulting meter output. This is done to determine if the unit is functioning properly. The testers are connected to the host PC through an RS-485 serial line. The host PC polls all the tester stations that are connected to it and collects data from those that have completed a calibration. It logs these data and stores the record in a format ready for export to the Maintenance, Accountability, Jobs, and Inventory Control (MAJIC) database. It also prints a report. The programs for the Automated Bicron Tester and the host are written in the C language.

  12. Automated design of infrared digital metamaterials by genetic algorithm

    Science.gov (United States)

    Sugino, Yuya; Ishikawa, Atsushi; Hayashi, Yasuhiko; Tsuruta, Kenji

    2017-08-01

    We demonstrate automatic design of infrared (IR) metamaterials using a genetic algorithm (GA) and experimentally characterize their IR properties. To implement the automated design scheme of the metamaterial structures, we adopt a digital metamaterial consisting of 7 × 7 Au nano-pixels with an area of 200 nm × 200 nm, and their placements are coded as binary genes in the GA optimization process. The GA combined with three-dimensional (3D) finite element method (FEM) simulation is developed and applied to automatically construct a digital metamaterial to exhibit pronounced plasmonic resonances at the target IR frequencies. Based on the numerical results, the metamaterials are fabricated on a Si substrate over an area of 1 mm × 1 mm by using an EB lithography, Cr/Au (2/20 nm) depositions, and liftoff process. In the FT-IR measurement, pronounced plasmonic responses of each metamaterial are clearly observed near the targeted frequencies, although the synthesized pixel arrangements of the metamaterials are seemingly random. The corresponding numerical simulations reveal the important resonant behavior of each pixel and their hybridized systems. Our approach is fully computer-aided without artificial manipulation, thus paving the way toward the novel device design for next-generation plasmonic device applications.

  13. On the engineering design for systematic integration of agent-orientation in industrial automation.

    Science.gov (United States)

    Yu, Liyong; Schüller, Andreas; Epple, Ulrich

    2014-09-01

    In today's automation industry, agent-oriented development of system functionalities appears to have a great potential for increasing autonomy and flexibility of complex operations, while lowering the workload of users. In this paper, we present a reference model for the harmonious and systematical integration of agent-orientation in industrial automation. Considering compatibility with existing automation systems and best practice, this model combines advantages of function block technology, service orientation and native description methods from the automation standard IEC 61131-3. This approach can be applied as a guideline for the engineering design of future agent-oriented automation systems. Copyright © 2014 ISA. Published by Elsevier Ltd. All rights reserved.

  14. Computer-Aided Design for Electron Microscopy

    Czech Academy of Sciences Publication Activity Database

    Lencová, Bohumila

    2004-01-01

    Roč. 6, č. 1 (2004), s. 51-53 ISSN 1439-4243 Institutional research plan: CEZ:AV0Z2065902 Keywords : magnetic electron lenses * accuracy of computation * computer-aided design Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering

  15. The automated design of materials far from equilibrium

    Science.gov (United States)

    Miskin, Marc Z.

    Automated design is emerging as a powerful concept in materials science. By combining computer algorithms, simulations, and experimental data, new techniques are being developed that start with high level functional requirements and identify the ideal materials that achieve them. This represents a radically different picture of how materials become functional in which technological demand drives material discovery, rather than the other way around. At the frontiers of this field, materials systems previously considered too complicated can start to be controlled and understood. Particularly promising are materials far from equilibrium. Material robustness, high strength, self-healing and memory are properties displayed by several materials systems that are intrinsically out of equilibrium. These and other properties could be revolutionary, provided they can first be controlled. This thesis conceptualizes and implements a framework for designing materials that are far from equilibrium. We show how, even in the absence of a complete physical theory, design from the top down is possible and lends itself to producing physical insight. As a prototype system, we work with granular materials: collections of athermal, macroscopic identical objects, since these materials function both as an essential component of industrial processes as well as a model system for many non-equilibrium states of matter. We show that by placing granular materials in the context of design, benefits emerge simultaneously for fundamental and applied interests. As first steps, we use our framework to design granular aggregates with extreme properties like high stiffness, and softness. We demonstrate control over nonlinear effects by producing exotic aggregates that stiffen under compression. Expanding on our framework, we conceptualize new ways of thinking about material design when automatic discovery is possible. We show how to build rules that link particle shapes to arbitrary granular packing

  16. An Automated System for Garment Texture Design Class Identification

    Directory of Open Access Journals (Sweden)

    Emon Kumar Dey

    2015-09-01

    Full Text Available Automatic identification of garment design class might play an important role in the garments and fashion industry. To achieve this, essential initial works are found in the literature. For example, construction of a garment database, automatic segmentation of garments from real life images, categorizing them into the type of garments such as shirts, jackets, tops, skirts, etc. It is now essential to find a system such that it will be possible to identify the particular design (printed, striped or single color of garment product for an automated system to recommend the garment trends. In this paper, we have focused on this specific issue and thus propose two new descriptors namely Completed CENTRIST (cCENTRIST and Ternary CENTRIST (tCENTRIST. To test these descriptors, we used two different publically available databases. The experimental results of these databases demonstrate that both cCENTRIST and tCENTRIST achieve nearly about 3% more accuracy than the existing state-of-the art methods.

  17. Design of a miniaturized solid state laser for automated assembly

    Science.gov (United States)

    Funck, Max C.; Dolkemeyer, Jan; Morasch, Valentin; Loosen, Peter

    2010-05-01

    A miniaturized solid state laser for marking applications has been developed featuring novel assembly strategies to reduce size, cost and assembly effort. Design and setup have been laid out with future automation of the assembly in mind. Using a high precision robot the optical components composing the laser system are directly placed on a planar substrate providing accurate positioning and alignment within a few microns. No adjustable mounts for mirrors and lenses are necessary, greatly simplifying the setup. Consisting of either a ND:YAG or a Nd:YVO4 crystal pumped with a fiber coupled diode laser, a q-switch for pulse generation and a beam expander the entire assembly is confined in a 100ml space and delivers 4 W of continuous output power at 1.064 μm with an efficiency greater than 40%. Pulse lengths of 10-20 ns and repetition rates of up to 150 kHz have been obtained with an acousto-optic modulator. In addition, a custom designed electro-optic modulator with integrated high voltage switch has been realized. A supply unit for the entire system, including scanner and water cooling, is integrated in a 19" industrial chassis and can be operated via a graphical user interface on a standard personal computer.

  18. Automated Hydraulic System Design and Power Management in Mobile Applications

    DEFF Research Database (Denmark)

    Pedersen, Henrik Clemmensen

    task is therefore to design the system so these losses may be minimised. The problem with this is that there exist no methods for how to do this, and the design task may generally be a very complex process, which requires substantial prior knowledge and experience. Having designed a systems no methods...... considering other design parameters like installation cost, complexity and system performance. The report begins with a presentation and definition of the problem considered and a review of the work that has been made within the area of hydraulic load sensing (LS) systems throughout the last three decades....... Through this, the different stability problems that are often encountered in LS-systems are explained along with how they may be avoided. In addition hereto an overview of the work that has been made in relation to electronic load sensing (ELS) systems is presented along with an overview of the other...

  19. Tevatron Electron Lenses: Design and Operation

    Energy Technology Data Exchange (ETDEWEB)

    Shiltsev, Vladimir; /Fermilab; Bishofberger, Kip; /Los Alamos; Kamerdzhiev, Vsevolod; /Fermilab; Kozub, Sergei; /Serpukhov, IHEP; Kufer, Matthew; Kuznetsov, Gennady; Martinez, Alexander; Olson, Marvin; Pfeffer, Howard; Saewert, Greg; Scarpine, Vic; /Fermilab /SLAC /Fermilab /Serpukhov, IHEP /Novosibirsk, IYF /Serpukhov, IHEP /Fermilab

    2008-08-01

    The beam-beam effects have been the dominating sources of beam loss and lifetime limitations in the Tevatron proton-antiproton collider [1]. Electron lenses were originally proposed for compensation of electromagnetic long-range and head-on beam-beam interactions of proton and antiproton beams [2]. Results of successful employment of two electron lenses built and installed in the Tevatron are reported in [3,4,5]. In this paper we present design features of the Tevatron electron lenses (TELs), discuss the generation of electron beams, describe different modes of operation and outline the technical parameters of various subsystems.

  20. A Multidisciplinary PBL Robot Control Project in Automation and Electronic Engineering

    Science.gov (United States)

    Hassan, Houcine; Domínguez, Carlos; Martínez, Juan-Miguel; Perles, Angel; Capella, Juan-Vicente; Albaladejo, José

    2015-01-01

    This paper presents a multidisciplinary problem-based learning (PBL) project consisting of the development of a robot arm prototype and the implementation of its control system. The project is carried out as part of Industrial Informatics (II), a compulsory third-year course in the Automation and Electronic Engineering (AEE) degree program at the…

  1. Data base systems in electronic design engineering

    Science.gov (United States)

    Williams, D.

    1980-01-01

    The concepts of an integrated design data base system (DBMS) as it might apply to an electronic design company are discussed. Data elements of documentation, project specifications, project tracking, firmware, software, electronic and mechanical design can be integrated and managed through a single DBMS. Combining the attributes of a DBMS data handler with specialized systems and functional data can provide users with maximum flexibility, reduced redundancy, and increased overall systems performance. Although some system overhead is lost due to redundancy in transitory data, it is believed the combination of the two data types is advisable rather than trying to do all data handling through a single DBMS.

  2. DESIGN ELEMENTS OF THE AUTOMATED CONTROL SYSTEMS PRODUCTION ENTERPRISES AVIATION INSTRUMEN

    OpenAIRE

    P. P. Dobrov

    2016-01-01

    There are considered the basics of organization of design of the automated  enterprise control systems elements of the aircraft instrument engineering enterprises; there are specified the stages of introduction of the AECS of the aircraft instrument engineering enterprises; there are considered the aspects of choice of means and tools of the enterprise automation. There is specified that it is very important to clearly define the goals, objectives and methods of automation, to take into accou...

  3. Design for Reliability of Power Electronic Systems

    DEFF Research Database (Denmark)

    Yang, Yongheng; Wang, Huai; Sangwongwanich, Ariya

    2018-01-01

    Power density, efficiency, cost, and reliability are the major challenges when designing a power electronic system. Latest advancements in power semiconductor devices (e.g., silicon carbide devices) and topological innovations have vital contributions to power density and efficiency. Nevertheless......, dedicated heat sink systems for thermal management are required to dissipate the power losses in power electronic systems; otherwise, the power devices will be heated up and eventually fail to operate. In addition, in many mission critical applications (e.g., marine systems), the operating condition (i.......e., mission profiles) is usually harsh, where the input power can change quickly and randomly, resulting in considerable temperature swings in the power electronics. This may induce failures to the power electronic systems. If remain untreated (i.e., ill-designed system without considering reliability...

  4. Automated magnetic divertor design for optimal power exhaust

    Energy Technology Data Exchange (ETDEWEB)

    Blommaert, Maarten

    2017-07-01

    The so-called divertor is the standard particle and power exhaust system of nuclear fusion tokamaks. In essence, the magnetic configuration hereby 'diverts' the plasma to a specific divertor structure. The design of this divertor is still a key issue to be resolved to evolve from experimental fusion tokamaks to commercial power plants. The focus of this dissertation is on one particular design requirement: avoiding excessive heat loads on the divertor structure. The divertor design process is assisted by plasma edge transport codes that simulate the plasma and neutral particle transport in the edge of the reactor. These codes are computationally extremely demanding, not in the least due to the complex collisional processes between plasma and neutrals that lead to strong radiation sinks and macroscopic heat convection near the vessel walls. One way of improving the heat exhaust is by modifying the magnetic confinement that governs the plasma flow. In this dissertation, automated design of the magnetic configuration is pursued using adjoint based optimization methods. A simple and fast perturbation model is used to compute the magnetic field in the vacuum vessel. A stable optimal design method of the nested type is then elaborated that strictly accounts for several nonlinear design constraints and code limitations. Using appropriate cost function definitions, the heat is spread more uniformly over the high-heat load plasma-facing components in a practical design example. Furthermore, practical in-parts adjoint sensitivity calculations are presented that provide a way to an efficient optimization procedure. Results are elaborated for a fictituous JET (Joint European Torus) case. The heat load is strongly reduced by exploiting an expansion of the magnetic flux towards the solid divertor structure. Subsequently, shortcomings of the perturbation model for magnetic field calculations are discussed in comparison to a free boundary equilibrium (FBE) simulation

  5. Bridging nanometer design-to-manufacturing gap: automated design rules correction and silicon verification

    Science.gov (United States)

    Karklin, Linard N.; Oren, Micha; Dudau, Dragos; Jordan, James D.

    2003-08-01

    Following Moore's Law semiconductor industry is going through a challenging transition from 180 nm to 130 nm manufacturing process geometries and rapidly approaching 90 nm geometries. The major challenges associated with the transition to nanometer design include: (1) Increasing design sizes and complexity (e.g. 300-400M transistors for FPGAs); (2) Increasing number of design rules (approaching 2000 for advanced 90 nm processes); (3) Increasing design cycle (4-9 months for ASICs); (4) Increasing design cost (advanced design flow cost $15M+). With the size and complexity of today's advanced ASICs and SoCs, the ability of designers to efficiently fix DRC errors is becoming a critical challenge impacting productivity and time-to-market. Designers need new EDA tools to process designs of very high complexity in shorter time. New tools should bridge design and process worlds by transparently providing designers with more detailed process (lithography) information. In this paper the authors will describe a method for manufacturing verification of automated design rule fixes. Many types of design rule violation are detected, automatically fixed, and verified by lithography simulation.

  6. Design of Stretchable Electronics Against Impact.

    Science.gov (United States)

    Yuan, J H; Pharr, M; Feng, X; Rogers, John A; Huang, Yonggang

    2016-10-01

    Stretchable electronics offer soft, biocompatible mechanical properties; these same properties make them susceptible to device failure associated with physical impact. This paper studies designs for stretchable electronics that resist failure from impacts due to incorporation of a viscoelastic encapsulation layer. Results indicate that the impact resistance depends on the thickness and viscoelastic properties of the encapsulation layer, as well as the duration of impact. An analytic model for the critical thickness of the encapsulation layer is established. It is shown that a commercially available, low modulus silicone material offers viscous properties that make it a good candidate as the encapsulation layer for stretchable electronics.

  7. Designs for a quantum electron microscope.

    Science.gov (United States)

    Kruit, P; Hobbs, R G; Kim, C-S; Yang, Y; Manfrinato, V R; Hammer, J; Thomas, S; Weber, P; Klopfer, B; Kohstall, C; Juffmann, T; Kasevich, M A; Hommelhoff, P; Berggren, K K

    2016-05-01

    One of the astounding consequences of quantum mechanics is that it allows the detection of a target using an incident probe, with only a low probability of interaction of the probe and the target. This 'quantum weirdness' could be applied in the field of electron microscopy to generate images of beam-sensitive specimens with substantially reduced damage to the specimen. A reduction of beam-induced damage to specimens is especially of great importance if it can enable imaging of biological specimens with atomic resolution. Following a recent suggestion that interaction-free measurements are possible with electrons, we now analyze the difficulties of actually building an atomic resolution interaction-free electron microscope, or "quantum electron microscope". A quantum electron microscope would require a number of unique components not found in conventional transmission electron microscopes. These components include a coherent electron beam-splitter or two-state-coupler, and a resonator structure to allow each electron to interrogate the specimen multiple times, thus supporting high success probabilities for interaction-free detection of the specimen. Different system designs are presented here, which are based on four different choices of two-state-couplers: a thin crystal, a grating mirror, a standing light wave and an electro-dynamical pseudopotential. Challenges for the detailed electron optical design are identified as future directions for development. While it is concluded that it should be possible to build an atomic resolution quantum electron microscope, we have also identified a number of hurdles to the development of such a microscope and further theoretical investigations that will be required to enable a complete interpretation of the images produced by such a microscope. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  8. Automated design synthesis of robotic/human workcells for improved manufacturing system design in hazardous environments

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Joshua M. [Los Alamos National Laboratory

    2012-06-12

    Manufacturing tasks that are deemed too hazardous for workers require the use of automation, robotics, and/or other remote handling tools. The associated hazards may be radiological or nonradiological, and based on the characteristics of the environment and processing, a design may necessitate robotic labor, human labor, or both. There are also other factors such as cost, ergonomics, maintenance, and efficiency that also effect task allocation and other design choices. Handling the tradeoffs of these factors can be complex, and lack of experience can be an issue when trying to determine if and what feasible automation/robotics options exist. To address this problem, we utilize common engineering design approaches adapted more for manufacturing system design in hazardous environments. We limit our scope to the conceptual and embodiment design stages, specifically a computational algorithm for concept generation and early design evaluation. In regard to concept generation, we first develop the functional model or function structure for the process, using the common 'verb-noun' format for describing function. A common language or functional basis for manufacturing was developed and utilized to formalize function descriptions and guide rules for function decomposition. Potential components for embodiment are also grouped in terms of this functional language and are stored in a database. The properties of each component are given as quantitative and qualitative criteria. Operators are also rated for task-relevant criteria which are used to address task compatibility. Through the gathering of process requirements/constraints, construction of the component database, and development of the manufacturing basis and rule set, design knowledge is stored and available for computer use. Thus, once the higher level process functions are defined, the computer can automate the synthesis of new design concepts through alternating steps of embodiment and function structure

  9. Electronics design office organization, methods and tools

    CERN Document Server

    Van der Bij, E

    2004-01-01

    The group TS-DEM offers a global service for the design, manufacturing and assembly of electronics modules for several hundreds of electronics engineers at CERN and its collaborating institutes. The Design Office in DEM determines and controls an overall planning, defines the resources required, solves the technical aspects and invoices the whole project. This involves technical resources provided by service contracts and supply contracts, but also negotiations with clients to be able to provide realistic plannings while still being able to handle urgent cases and high-workload periods.

  10. GENIUS : An integrated environment for supporting the design of generic automated negotiators

    NARCIS (Netherlands)

    Lin, R.; Kraus, S.; Baarslag, T.; Tykhonov, D.; Hindriks, K.; Jonker, C.M.

    2012-01-01

    The design of automated negotiators has been the focus of abundant research in recent years. However, due to difficulties involved in creating generalized agents that can negotiate in several domains and against human counterparts, many automated negotiators are domain specific and their behavior

  11. Parameterized Automated Generic Model for Aircraft Wing Structural Design and Mesh Generation for Finite Element Analysis

    OpenAIRE

    Sohaib, Muhammad

    2011-01-01

    This master thesis work presents the development of a parameterized automated generic model for the structural design of an aircraft wing. Furthermore, in order to perform finite element analysis on the aircraft wing geometry, the process of finite element mesh generation is automated. Aircraft conceptual design is inherently a multi-disciplinary design process which involves a large number of disciplines and expertise. In this thesis work, it is investigated how high-end CAD software‟s can b...

  12. Laser Opto-Electronic Correlator for Robotic Vision Automated Pattern Recognition

    Science.gov (United States)

    Marzwell, Neville

    1995-01-01

    A compact laser opto-electronic correlator for pattern recognition has been designed, fabricated, and tested. Specifically it is a translation sensitivity adjustable compact optical correlator (TSACOC) utilizing convergent laser beams for the holographic filter. Its properties and performance, including the location of the correlation peak and the effects of lateral and longitudinal displacements for both filters and input images, are systematically analyzed based on the nonparaxial approximation for the reference beam. The theoretical analyses have been verified in experiments. In applying the TSACOC to important practical problems including fingerprint identification, we have found that the tolerance of the system to the input lateral displacement can be conveniently increased by changing a geometric factor of the system. The system can be compactly packaged using the miniature laser diode sources and can be used in space by the National Aeronautics and Space Administration (NASA) and ground commercial applications which include robotic vision, and industrial inspection of automated quality control operations. The personnel of Standard International will work closely with the Jet Propulsion Laboratory (JPL) to transfer the technology to the commercial market. Prototype systems will be fabricated to test the market and perfect the product. Large production will follow after successful results are achieved.

  13. Automated Detection of Sepsis Using Electronic Medical Record Data: A Systematic Review.

    Science.gov (United States)

    Despins, Laurel A

    Severe sepsis and septic shock are global issues with high mortality rates. Early recognition and intervention are essential to optimize patient outcomes. Automated detection using electronic medical record (EMR) data can assist this process. This review describes automated sepsis detection using EMR data. PubMed retrieved publications between January 1, 2005 and January 31, 2015. Thirteen studies met study criteria: described an automated detection approach with the potential to detect sepsis or sepsis-related deterioration in real or near-real time; focused on emergency department and hospitalized neonatal, pediatric, or adult patients; and provided performance measures or results indicating the impact of automated sepsis detection. Detection algorithms incorporated systemic inflammatory response and organ dysfunction criteria. Systems in nine studies generated study or care team alerts. Care team alerts did not consistently lead to earlier interventions. Earlier interventions did not consistently translate to improved patient outcomes. Performance measures were inconsistent. Automated sepsis detection is potentially a means to enable early sepsis-related therapy but current performance variability highlights the need for further research.

  14. Preface to the special section on human factors and automation in vehicles: designing highly automated vehicles with the driver in mind.

    Science.gov (United States)

    Merat, Natasha; Lee, John D

    2012-10-01

    This special section brings together diverse research regarding driver interaction with advanced automotive technology to guide design of increasingly automated vehicles. Rapidly evolving vehicle automation will likely change cars and trucks more in the next 5 years than the preceding 50, radically redefining what it means to drive. This special section includes 10 articles from European and North American researchers reporting simulator and naturalistic driving studies. Little research has considered the consequences of fully automated driving, with most focusing on lane-keeping and speed control systems individually. The studies reveal two underlying design philosophies: automate driving versus support driving. Results of several studies, consistent with previous research in other domains, suggest that the automate philosophy can delay driver responses to incidents in which the driver has to intervene and take control from the automation. Understanding how to orchestrate the transfer or sharing of control between the system and the driver, particularly in critical incidents, emerges as a central challenge. Designers should not assume that automation can substitute seamlessly for a human driver, nor can they assume that the driver can safely accommodate the limitations of automation. Designers, policy makers, and researchers must give careful consideration to what role the person should have in highly automated vehicles and how to support the driver if the driver is to be responsible for vehicle control. As in other domains, driving safety increasingly depends on the combined performance of the human and automation, and successful designs will depend on recognizing and supporting the new roles of the driver.

  15. Design of Networked Home Automation System Based on μCOS-II and AMAZON

    Directory of Open Access Journals (Sweden)

    Liu Jianfeng

    2015-01-01

    Full Text Available In recent years, with the popularity of computers and smart phones and the development of intelligent building in electronics industry, people’s requirement of living environment is gradually changing. The intelligent home furnishing building has become the new focus of people purchasing. And the networked home automation system which relies on the advanced network technology to connect with air conditioning, lighting, security, curtains, TV, water heater and other home furnishing systems into a local area network becomes a networked control system. μC /OS is a real-time operating system with the free open-source code, the compact structure and the preemptive real-time kernel. In this paper, the author focuses on the design of home furnishing total controller based on AMAZON multimedia processor and μC/OS-II real-time operating system, and achieves the remote access connection and control through the Ethernet.

  16. Design for Reliability of Power Electronic Systems

    DEFF Research Database (Denmark)

    Wang, Huai; Ma, Ke; Blaabjerg, Frede

    2012-01-01

    Advances in power electronics enable efficient and flexible processing of electric power in the application of renewable energy sources, electric vehicles, adjustable-speed drives, etc. More and more efforts are devoted to better power electronic systems in terms of reliability to ensure high...... availability, long lifetime, sufficient robustness, low maintenance cost and low cost of energy. However, the reliability predictions are still dominantly according to outdated models and terms, such as MIL-HDBK-217F handbook models, Mean-Time-To-Failure (MTTF), and Mean-Time-Between-Failures (MTBF......). A collection of methodologies based on Physics-of-Failure (PoF) approach and mission profile analysis are presented in this paper to perform reliability-oriented design of power electronic systems. The corresponding design procedures and reliability prediction models are provided. Further on, a case study...

  17. Analog Electronic Filters Theory, Design and Synthesis

    CERN Document Server

    Dimopoulos, Hercules G

    2012-01-01

    Filters are essential subsystems in a huge variety of electronic systems. Filter applications are innumerable; they are used for noise reduction, demodulation, signal detection, multiplexing, sampling, sound and speech processing, transmission line equalization and image processing, to name just a few. In practice, no electronic system can exist without filters. They can be found in everything from power supplies to mobile phones and hard disk drives and from loudspeakers and MP3 players to home cinema systems and broadband Internet connections. This textbook introduces basic concepts and methods and the associated mathematical and computational tools employed in electronic filter theory, synthesis and design.  This book can be used as an integral part of undergraduate courses on analog electronic filters. Includes numerous, solved examples, applied examples and exercises for each chapter. Includes detailed coverage of active and passive filters in an independent but correlated manner. Emphasizes real filter...

  18. Fractal design concepts for stretchable electronics.

    Science.gov (United States)

    Fan, Jonathan A; Yeo, Woon-Hong; Su, Yewang; Hattori, Yoshiaki; Lee, Woosik; Jung, Sung-Young; Zhang, Yihui; Liu, Zhuangjian; Cheng, Huanyu; Falgout, Leo; Bajema, Mike; Coleman, Todd; Gregoire, Dan; Larsen, Ryan J; Huang, Yonggang; Rogers, John A

    2014-01-01

    Stretchable electronics provide a foundation for applications that exceed the scope of conventional wafer and circuit board technologies due to their unique capacity to integrate with soft materials and curvilinear surfaces. The range of possibilities is predicated on the development of device architectures that simultaneously offer advanced electronic function and compliant mechanics. Here we report that thin films of hard electronic materials patterned in deterministic fractal motifs and bonded to elastomers enable unusual mechanics with important implications in stretchable device design. In particular, we demonstrate the utility of Peano, Greek cross, Vicsek and other fractal constructs to yield space-filling structures of electronic materials, including monocrystalline silicon, for electrophysiological sensors, precision monitors and actuators, and radio frequency antennas. These devices support conformal mounting on the skin and have unique properties such as invisibility under magnetic resonance imaging. The results suggest that fractal-based layouts represent important strategies for hard-soft materials integration.

  19. Fractal design concepts for stretchable electronics

    Science.gov (United States)

    Fan, Jonathan A.; Yeo, Woon-Hong; Su, Yewang; Hattori, Yoshiaki; Lee, Woosik; Jung, Sung-Young; Zhang, Yihui; Liu, Zhuangjian; Cheng, Huanyu; Falgout, Leo; Bajema, Mike; Coleman, Todd; Gregoire, Dan; Larsen, Ryan J.; Huang, Yonggang; Rogers, John A.

    2014-02-01

    Stretchable electronics provide a foundation for applications that exceed the scope of conventional wafer and circuit board technologies due to their unique capacity to integrate with soft materials and curvilinear surfaces. The range of possibilities is predicated on the development of device architectures that simultaneously offer advanced electronic function and compliant mechanics. Here we report that thin films of hard electronic materials patterned in deterministic fractal motifs and bonded to elastomers enable unusual mechanics with important implications in stretchable device design. In particular, we demonstrate the utility of Peano, Greek cross, Vicsek and other fractal constructs to yield space-filling structures of electronic materials, including monocrystalline silicon, for electrophysiological sensors, precision monitors and actuators, and radio frequency antennas. These devices support conformal mounting on the skin and have unique properties such as invisibility under magnetic resonance imaging. The results suggest that fractal-based layouts represent important strategies for hard-soft materials integration.

  20. DESIGN ELEMENTS OF THE AUTOMATED CONTROL SYSTEMS PRODUCTION ENTERPRISES AVIATION INSTRUMEN

    Directory of Open Access Journals (Sweden)

    P. P. Dobrov

    2016-01-01

    Full Text Available There are considered the basics of organization of design of the automated  enterprise control systems elements of the aircraft instrument engineering enterprises; there are specified the stages of introduction of the AECS of the aircraft instrument engineering enterprises; there are considered the aspects of choice of means and tools of the enterprise automation. There is specified that it is very important to clearly define the goals, objectives and methods of automation, to take into account the economic component  of design and implementation, and regulatory requirements for automation upon organization of design of the AECS elements of the aircraft instrument engineering enterprises. These requirements are recommended to be reflected in the design technical specification and in the business plan of automation, which is an organizational and economic design tool. An important element of the business plan of automation shall be a financial justification, cost calculation and determination of the schedule of scientific-research and development works, and other important stages of design of the AECS elements. It was found that the most effective approach to the organization of design of the AECS elements from an economic and organizational point of view is the cooperation of engineering and IT departments of enterprises and technical professionals (units of third-party developers. It was determined that an important technology to optimize the design process is the application of the integrated automation design systems. The recommendations can form the basis of the process of improving of design of the automated enterprise control systems elements at domestic and foreign aircraft instrument engineering enterprises.

  1. Industrial Robot Automation in Solving Non-Vacuum Electron-Beam Welding Problems

    OpenAIRE

    Borovik Vasiliy; Shatravin Vladislav; Junusov Il’jas; Shashev Dmitri; Kornilov Sergei; Rempe Nikolai; Shidlovskiy Stanislav

    2016-01-01

    The paper describes one modeling automated hardware-software system to develop additive technologically - based products. Algorithm synthesis for industrial robot control was performed. In this case, the operating tool is an electron -beam projector with plasma emitter. The model testing results of thermal processes (in 3D-enqueuing) proceeding within additive substrate material system have been described. The modeling results revealed those required parameters of emission power which would p...

  2. Automated Monte Carlo biasing for photon-generated electrons near surfaces.

    Energy Technology Data Exchange (ETDEWEB)

    Franke, Brian Claude; Crawford, Martin James; Kensek, Ronald Patrick

    2009-09-01

    This report describes efforts to automate the biasing of coupled electron-photon Monte Carlo particle transport calculations. The approach was based on weight-windows biasing. Weight-window settings were determined using adjoint-flux Monte Carlo calculations. A variety of algorithms were investigated for adaptivity of the Monte Carlo tallies. Tree data structures were used to investigate spatial partitioning. Functional-expansion tallies were used to investigate higher-order spatial representations.

  3. Automated Design and Analysis Tool for CLV/CEV Composite and Metallic Structural Components Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation of the proposed effort is a unique automated process for the analysis, design, and sizing of CLV/CEV composite and metallic structures. This developed...

  4. Automated Design and Analysis Tool for CEV Structural and TPS Components Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The innovation of the proposed effort is a unique automated process for the analysis, design, and sizing of CEV structures and TPS. This developed process will...

  5. EcoDesign 2.0 - Quantitative EcoDesign within Drives and Automation Technologies

    DEFF Research Database (Denmark)

    Auer, Johannes

    approaches to design the above in a comprehensive and yet feasible way, applicable in industrial settings – and with regard to special conditions opposed by long application life times and high customer investments that may be involved.  This then led to the working hypothesis, that instead of dealing......The PhD project has its research background mainly in the fields of product development & design, manufacturing systems and quantitative sustainability assessment, incl. environmental Life Cycle Assessment (LCA). Related organizational and management research is also drawn upon as well as systems...... challenges, the overall objective of the PhD project was set to create supportive means (tools, methods, models, etc.) which stimulate design of non-sub-optimised solutions through focussing on improving automation and drive technologies in an application context. Based upon this, the research was defined...

  6. A Review Of Design And Control Of Automated Guided Vehicle Systems

    OpenAIRE

    Le-Anh, Tuan; Koster, René

    2004-01-01

    textabstractThis paper presents a review on design and control of automated guided vehicle systems. We address most key related issues including guide-path design, estimating the number of vehicles, vehicle scheduling, idle-vehicle positioning, battery management, vehicle routing, and conflict resolution. We discuss and classify important models and results from key publications in literature on automated guided vehicle systems, including often-neglected areas, such as idle-vehicle positionin...

  7. Design and fabrication of an automated temperature programmed ...

    Indian Academy of Sciences (India)

    A completely automated temperature-programmed reaction (TPR) system for carrying out gas-solid catalytic reactions under atmospheric flow conditions is fabricated to study CO and hydrocarbon oxidation, and NO reduction. The system consists of an all-stainless steel UHV system, quadrupole mass spectrometer SX200 ...

  8. Structured design of an automated monitoring tool for pest species

    NARCIS (Netherlands)

    Mul, Monique F.; Ploegaert, Johan P.M.; George, David R.; Meerburg, Bastiaan G.; Dicke, Marcel; Groot Koerkamp, Peter W.G.

    2016-01-01

    Pests and diseases in agricultural systems cause severe production losses with associated economic impact. Integrated Pest Management (IPM) is a sustainable method to limit these losses. For improved implementation of IPM, fully automated monitoring tools are needed to provide instantaneous pest

  9. Electronic cigarettes: product characterisation and design considerations

    OpenAIRE

    Brown, Christopher J.; Cheng, James M

    2014-01-01

    Objective To review the available evidence regarding electronic cigarette (e-cigarette) product characterisation and design features in order to understand their potential impact on individual users and on public health. Methods Systematic literature searches in 10 reference databases were conducted through October 2013. A total of 14 articles and documents and 16 patents were included in this analysis. Results Numerous disposable and reusable e-cigarette product options exist, representing w...

  10. Design and Implementation of GSM Based Automated Home Security System

    Directory of Open Access Journals (Sweden)

    Love Aggarwal

    2014-05-01

    Full Text Available The Automated Home Security System aims at building a security system for common households using GSM modem, sensors and microcontroller. Since many years, impeccable security system has been the prime need of every man who owns a house. The increasing crime rate has further pressed the need for it. Our system is an initiative in this direction. The system provides security function by monitoring the surroundings at home for intruders, fire, gas leakages etc. using sensors and issue alerts to the owners and local authorities by using GSM via SMS. It provides the automation function as it can control (On/Off the various home appliances while the owners are away via SMS. Thus the Automated Home Security System is self-sufficient and can be relied upon undoubtedly. Also, it is capable of establishing two way communication with its owner so that he/she can keep a watch on his/her home via sensor information or live video streaming. A camera can be installed for continuous monitoring of the system and its surroundings. The system consists of two main parts: hardware and software. Hardware consists of Microcontroller, Sensors, Buzzer and GSM modem while software is implemented by tools using Embedded ‘C’.

  11. Design for the automation of composite wind turbine blade manufacture

    Science.gov (United States)

    Polcari, M. J.; White, K. D.; Sherwood, J. A.

    2016-10-01

    The majority of large wind turbine blades are manufactured from textile-reinforced resin-infused composites using an open mold. The placement of the textile reinforcements in the mold is traditionally accomplished by a manual process where dozens of workers hand place each dry fabric in the mold. Depending on the level of skill and experience of each worker and the relative complexity of the mold geometry, local areas may exhibit out-of-plane wrinkling and in-plane waviness. Fabric imperfections such as these can adversely impact the strength and stiffness of the blade, thereby compromising its durability in service. In an effort to reduce the variabilities associated with a manual-labor process, an automated piecewise shifting method has been proposed for fabric placement. This automated layup method saves time on the preform process and reduces variability from blade to blade. In the current research the automated shifting layup method is investigated using a robust and easy-to-use finite element modelling approach. User-defined material models utilizing a mesoscopic unit-cell modeling approach are linked with Abaqus to capture the evolution of the fabric shear stiffness and changes in the fiber orientations during the fabric-placement process. The simulation approach is demonstrated for the geometry of the trailing edge of a typical wind turbine blade. The simulation considers the mechanical behavior of the fabric and reliably predicts fabric deformation and failure zones.

  12. Designing of smart home automation system based on Raspberry Pi

    Science.gov (United States)

    Saini, Ravi Prakash; Singh, Bhanu Pratap; Sharma, Mahesh Kumar; Wattanawisuth, Nattapol; Leeprechanon, Nopbhorn

    2016-03-01

    Locally networked or remotely controlled home automation system becomes a popular paradigm because of the numerous advantages and is suitable for academic research. This paper proposes a method for an implementation of Raspberry Pi based home automation system presented with an android phone access interface. The power consumption profile across the connected load is measured accurately through programming. Users can access the graph of total power consumption with respect to time worldwide using their Dropbox account. An android application has been developed to channelize the monitoring and controlling operation of home appliances remotely. This application facilitates controlling of operating pins of Raspberry Pi by pressing the corresponding key for turning "on" and "off" of any desired appliance. Systems can range from the simple room lighting control to smart microcontroller based hybrid systems incorporating several other additional features. Smart home automation systems are being adopted to achieve flexibility, scalability, security in the sense of data protection through the cloud-based data storage protocol, reliability, energy efficiency, etc.

  13. Designing of smart home automation system based on Raspberry Pi

    Energy Technology Data Exchange (ETDEWEB)

    Saini, Ravi Prakash; Singh, Bhanu Pratap [B K Birla Institute of Engineering & Technology, Pilani, Rajasthan (India); Sharma, Mahesh Kumar; Wattanawisuth, Nattapol; Leeprechanon, Nopbhorn, E-mail: Dr.N.L@ieee.org [Thammasat University, Rangsit Campus, Pathum Thani (Thailand)

    2016-03-09

    Locally networked or remotely controlled home automation system becomes a popular paradigm because of the numerous advantages and is suitable for academic research. This paper proposes a method for an implementation of Raspberry Pi based home automation system presented with an android phone access interface. The power consumption profile across the connected load is measured accurately through programming. Users can access the graph of total power consumption with respect to time worldwide using their Dropbox account. An android application has been developed to channelize the monitoring and controlling operation of home appliances remotely. This application facilitates controlling of operating pins of Raspberry Pi by pressing the corresponding key for turning “on” and “off” of any desired appliance. Systems can range from the simple room lighting control to smart microcontroller based hybrid systems incorporating several other additional features. Smart home automation systems are being adopted to achieve flexibility, scalability, security in the sense of data protection through the cloud-based data storage protocol, reliability, energy efficiency, etc.

  14. Towards automation of control software: A review of challenges in mechatronic design

    NARCIS (Netherlands)

    Alvarez Cabrera, A.A.; Foeken, M.J.; Tekin, O.A.; Woestenenk, Krijn; Erden, M.S.; de Schutter, B.; Tooren, M.J.L.; Babuska, R.; van Houten, Frederikus J.A.M.; Tomiyama, T.

    2010-01-01

    Development of mechatronic systems requires collaboration among experts from different design domains. In this paper the authors identify a set of challenges related to the design of mechatronic systems. The challenges are mostly related to integration of design and analysis tools, and automation of

  15. Performance Evaluation of a Software Engineering Tool for Automated Design of Cooling Systems in Injection Moulding

    NARCIS (Netherlands)

    Jauregui Becker, Juan Manuel; Tosello, Guido; Houten, Fred J.A.M.; Hansen, Hans N.

    2013-01-01

    This paper presents a software tool for automating the design of cooling systems for injection moulding and a validation of its performance. Cooling system designs were automatically generated by the proposed software tool and by applying a best practice tool engineering design approach. The two

  16. Development and Evaluation of an Automated, Home-Based, Electronic Questionnaire for Detecting COPD Exacerbations

    Directory of Open Access Journals (Sweden)

    Francisco de B. Velazquez-Peña

    2015-01-01

    Full Text Available Collaboration between patients and their medical and technical experts enabled the development of an automated questionnaire for the early detection of COPD exacerbations (AQCE. The questionnaire consisted of fourteen questions and was implemented on a computer system for use by patients at home in an un-supervised environment. Psychometric evaluation was conducted after a 6-month field trial. Fifty-two patients were involved in the development of the questionnaire. Reproducibility was studied using 19 patients (ICC = 0.94. Sixteen out of the 19 subjects started the 6 month-field trial with the computer application. Cronbach’s alpha of 0.81 was achieved. In the concurrent validity analysis, a correlation of 0.80 (p = 0.002 with the CCQ was reported. The results suggest that AQCE is a valid and reliable questionnaire, showing that an automated home-based electronic questionnaire may enable early detection of exacerbations of COPD.

  17. Electronic bolus design impacts on administration.

    Science.gov (United States)

    Hentz, F; Umstätter, C; Gilaverte, S; Prado, O R; Silva, C J A; Monteiro, A L G

    2014-06-01

    Electronic identification of animals has become increasingly important worldwide to improve and ensure traceability. In warm and hot climates, such as Brazil, boluses can have advantages over ear tags as the internal devices reduce the risks of ear tag losses, tissue damage, and lesions on the ear. Electronic boluses, however, are often perceived as having negative characteristics, including reported difficulties of administration in small ruminants. This paper describes the factors associated with bolus design that affect the swallowing of a bolus in sheep. Other factors that might influence bolus swallowing time have also been considered. In addition, the effect of bolus design on its performance was evaluated. A total of 56 Suffolk ewes were used to assess the ease of administration and retention of 3 types of electronic ruminal boluses (mini, 11.5 × 58.0 mm and 21.7 g; small, 14.8 × 48.5 mm and 29.5 g; standard, 19.3 × 69.8 mm and 74.4 g) during a whole productive year, including pregnancy and lamb suckling. Ewe age (5.6 ± 2.3 yr) and weight (85.07 ± 8.2 kg BW) were recorded, as well as time for bolus swallowing. The deglutition of the bolus and any resulting blockages in the esophagus were monitored by visual observations. Retention and readability of the boluses were regularly monitored for d 1, wk 1, mo 1, and every mo until 1 yr. Time for bolus swallowing differed substantially with bolus type and was greater (P 0.05). The bolus o.d. and length were positively correlated with swallowing time (P electronic boluses showed 100% retention rate, and at 12 mo, bolus retention was 100%, 94.5%, and 100% for mini, small, and standard boluses, respectively (P > 0.05). At 12 mo, all boluses showed 100% readability, except for small boluses, which had a readability of 94.5%. In conclusion, bolus design affected swallowing time and bolus readability. A reduction in boluses length and o.d. needs to be carried out to provide ease of administration and for boluses to

  18. Development of an automated system for the operation of an electron beam accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Somessari, Samir L.; Moura, João A.; Calvo, Wilson Ap. Parejo, E-mail: somessar@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil)

    2017-11-01

    Electron beam accelerators are used in many applications, such as basic physical research, chemistry, medicine, molecular biology, microelectronics, agriculture and industry, among others. The majority of the accelerators have electrons from a hot tungsten filament and their energy is increased as it passes through an electric field in the vacuum chamber. For industrial purposes, the most common model is Dynamitrons®. At IPEN-CNEN/SP, there is an electron beam accelerator Dynamitron® Type (Manufactured by RDI- Radiation Dynamics Inc., 1978) model DC1500/25/4. The technology applied was available in the 60's and 70's, but, nowadays is obsolete. Moreover, there are not original spare parts for this equipment any longer. The aim of this work is to develop a nationalized automated operation system for the accelerator, to replace the old equipment. (author)

  19. High performance integer arithmetic circuit design on FPGA architecture, implementation and design automation

    CERN Document Server

    Palchaudhuri, Ayan

    2016-01-01

    This book describes the optimized implementations of several arithmetic datapath, controlpath and pseudorandom sequence generator circuits for realization of high performance arithmetic circuits targeted towards a specific family of the high-end Field Programmable Gate Arrays (FPGAs). It explores regular, modular, cascadable, and bit-sliced architectures of these circuits, by directly instantiating the target FPGA-specific primitives in the HDL. Every proposed architecture is justified with detailed mathematical analyses. Simultaneously, constrained placement of the circuit building blocks is performed, by placing the logically related hardware primitives in close proximity to one another by supplying relevant placement constraints in the Xilinx proprietary “User Constraints File”. The book covers the implementation of a GUI-based CAD tool named FlexiCore integrated with the Xilinx Integrated Software Environment (ISE) for design automation of platform-specific high-performance arithmetic circuits from us...

  20. Designing Interactive Electronic Module in Chemistry Lessons

    Science.gov (United States)

    Irwansyah, F. S.; Lubab, I.; Farida, I.; Ramdhani, M. A.

    2017-09-01

    This research aims to design electronic module (e-module) oriented to the development of students’ chemical literacy on the solution colligative properties material. This research undergoes some stages including concept analysis, discourse analysis, storyboard design, design development, product packaging, validation, and feasibility test. Overall, this research undertakes three main stages, namely, Define (in the form of preliminary studies); Design (designing e-module); Develop (including validation and model trial). The concept presentation and visualization used in this e-module is oriented to chemical literacy skills. The presentation order carries aspects of scientific context, process, content, and attitude. Chemists and multi media experts have done the validation to test the initial quality of the products and give a feedback for the product improvement. The feasibility test results stated that the content presentation and display are valid and feasible to be used with the value of 85.77% and 87.94%. These values indicate that this e-module oriented to students’ chemical literacy skills for the solution colligative properties material is feasible to be used.

  1. Designing automation for complex work environments under different levels of stress.

    Science.gov (United States)

    Sauer, Juergen; Nickel, Peter; Wastell, David

    2013-01-01

    This article examines the effectiveness of different forms of static and adaptable automation under low- and high-stress conditions. Forty participants were randomly assigned to one of four experimental conditions, comparing three levels of static automation (low, medium and high) and one level of adaptable automation, with the environmental stressor (noise) being varied as a within-subjects variable. Participants were trained for 4 h on a simulation of a process control environment, called AutoCAMS, followed by a 2.5-h testing session. Measures of performance, psychophysiology and subjective reactions were taken. The results showed that operators preferred higher levels of automation under noise than under quiet conditions. A number of parameters indicated negative effects of noise exposure, such as performance impairments, physiological stress reactions and higher mental workload. It also emerged that adaptable automation provided advantages over low and intermediate static automation, with regard to mental workload, effort expenditure and diagnostic performance. The article concludes that for the design of automation a wider range of operational scenarios reflecting adverse as well as ideal working conditions needs to be considered. Copyright © 2012 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  2. Industrial Robot Automation in Solving Non-Vacuum Electron-Beam Welding Problems

    Directory of Open Access Journals (Sweden)

    Borovik Vasiliy

    2016-01-01

    Full Text Available The paper describes one modeling automated hardware-software system to develop additive technologically - based products. Algorithm synthesis for industrial robot control was performed. In this case, the operating tool is an electron -beam projector with plasma emitter. The model testing results of thermal processes (in 3D-enqueuing proceeding within additive substrate material system have been described. The modeling results revealed those required parameters of emission power which would provide the melting of additive material (TiC excluding boiling.

  3. Automated determination of size and morphology information from soot transmission electron microscope (TEM)-generated images

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Cheng; Chan, Qing N., E-mail: qing.chan@unsw.edu.au; Zhang, Renlin; Kook, Sanghoon; Hawkes, Evatt R.; Yeoh, Guan H. [UNSW, School of Mechanical and Manufacturing Engineering (Australia); Medwell, Paul R. [The University of Adelaide, Centre for Energy Technology (Australia)

    2016-05-15

    The thermophoretic sampling of particulates from hot media, coupled with transmission electron microscope (TEM) imaging, is a combined approach that is widely used to derive morphological information. The identification and the measurement of the particulates, however, can be complex when the TEM images are of low contrast, noisy, and have non-uniform background signal level. The image processing method can also be challenging and time consuming, when the samples collected have large variability in shape and size, or have some degree of overlapping. In this work, a three-stage image processing sequence is presented to facilitate time-efficient automated identification and measurement of particulates from the TEM grids. The proposed processing sequence is first applied to soot samples that were thermophoretically sampled from a laminar non-premixed ethylene-air flame. The parameter values that are required to be set to facilitate the automated process are identified, and sensitivity of the results to these parameters is assessed. The same analysis process is also applied to soot samples that were acquired from an externally irradiated laminar non-premixed ethylene-air flame, which have different geometrical characteristics, to assess the morphological dependence of the proposed image processing sequence. Using the optimized parameter values, statistical assessments of the automated results reveal that the largest discrepancies that are associated with the estimated values of primary particle diameter, fractal dimension, and prefactor values of the aggregates for the tested cases, are approximately 3, 1, and 10 %, respectively, when compared with the manual measurements.

  4. An Automated Design-flow for FPGA-based Sequential Simulation

    NARCIS (Netherlands)

    Wolkotte, P.T.; Rutgers, J.H.; Holzenspies, P.K.F.; Westmijze, M.; Westmijze, M.; Blumink, R.; Smit, Gerardus Johannes Maria

    In this paper we describe the automated design flow that will transform and map a given homogeneous or heterogeneous hardware design into an FPGA that performs a cycle accurate simulation. The flow replaces the required manually performed transformation and can be embedded in existing standard

  5. A Review Of Design And Control Of Automated Guided Vehicle Systems

    NARCIS (Netherlands)

    T. Le-Anh (Tuan); M.B.M. de Koster (René)

    2004-01-01

    textabstractThis paper presents a review on design and control of automated guided vehicle systems. We address most key related issues including guide-path design, estimating the number of vehicles, vehicle scheduling, idle-vehicle positioning, battery management, vehicle routing, and conflict

  6. The design of 3D scaffold for tissue engineering using automated scaffold design algorithm.

    Science.gov (United States)

    Mahmoud, Shahenda; Eldeib, Ayman; Samy, Sherif

    2015-06-01

    Several progresses have been introduced in the field of bone regenerative medicine. A new term tissue engineering (TE) was created. In TE, a highly porous artificial extracellular matrix or scaffold is required to accommodate cells and guide their growth in three dimensions. The design of scaffolds with desirable internal and external structure represents a challenge for TE. In this paper, we introduce a new method known as automated scaffold design (ASD) for designing a 3D scaffold with a minimum mismatches for its geometrical parameters. The method makes use of k-means clustering algorithm to separate the different tissues and hence decodes the defected bone portions. The segmented portions of different slices are registered to construct the 3D volume for the data. It also uses an isosurface rendering technique for 3D visualization of the scaffold and bones. It provides the ability to visualize the transplanted as well as the normal bone portions. The proposed system proves good performance in both the segmentation results and visualizations aspects.

  7. OPTIMAL DESIGN ALGORITHM FOR FAULT TOLERANT INFORMATION SYSTEMS USED FOR PROCESSING ELECTRONIC MEDICAL RECORDS

    Directory of Open Access Journals (Sweden)

    P. V. Melyushin

    2014-01-01

    Full Text Available The paper considers problems on designing of medical information systems and proposes an approach to creation of a highly reliable automated system for processing electronic medical records on the basis of file allocation optimization in the network nodes. A mathematical model has been developed for optimal distribution of the files in the network nodes and an experimental investigation of two schemes of medical information systems has been executed in the paper.

  8. The Design of an Automated Workflow for Metadata Generation

    Science.gov (United States)

    Manso-Callejo, Miguel; Wachowicz, Mónica; Bernabé-Poveda, Miguel

    The important role of digital resources relies on whether metadata is available and has been correctly catalogued and indexed so that the user can discover and use geospatial datasets. However, the cost and the error-proneness in the manual metadata creation, the lack of information provided by the producers of geospatial datasets and the lack of experience in cataloguing have motivated us to propose a new workflow for the automated metadata generation for geospatial datasets. This paper describes this workflow based on tasks synchronization that gives support for four metadata functions: discovery, use, evaluate and retrieval of digital geodata. The workflow was implemented using a multi-tier architecture system where the Data, Application and User Tiers can run a single use application as well as web services. The prototype evaluation is discussed in terms of the type of metadata being generated and the type of metadata function being supported by the workflow.

  9. Model-driven design using IEC 61499 a synchronous approach for embedded and automation systems

    CERN Document Server

    Yoong, Li Hsien; Bhatti, Zeeshan E; Kuo, Matthew M Y

    2015-01-01

    This book describes a novel approach for the design of embedded systems and industrial automation systems, using a unified model-driven approach that is applicable in both domains.  The authors illustrate their methodology, using the IEC 61499 standard as the main vehicle for specification, verification, static timing analysis and automated code synthesis.  The well-known synchronous approach is used as the main vehicle for defining an unambiguous semantics that ensures determinism and deadlock freedom. The proposed approach also ensures very efficient implementations either on small-scale embedded devices or on industry-scale programmable automation controllers (PACs). It can be used for both centralized and distributed implementations. Significantly, the proposed approach can be used without the need for any run-time support. This approach, for the first time, blurs the gap between embedded systems and automation systems and can be applied in wide-ranging applications in automotive, robotics, and industri...

  10. Tevatron Electron Lenses: Design and Operation

    Energy Technology Data Exchange (ETDEWEB)

    Shiltsev, Vladimir; /Fermilab; Bishofberger, Kip; /Los Alamos; Kamerdzhiev, Vsevolod; /Fermilab; Kozub, Sergei; /Serpukhov, IHEP; Kufer, Matthew; Kuznetsov, Gennady; Martinez, Alexander; Olson, Marvin; Pfeffer, Howard; Saewert, Greg; Scarpine, Vic; /Fermilab; Seryi, Andrei; /SLAC; Solyak, Nikolai; /Fermilab; Sytnik, Veniamin; /Serpukhov, IHEP; Tiunov, Mikhail; /Novosibirsk, IYF; Tkachenko, Leonid; /Serpukhov, IHEP; Wildman, David; Wolff, Daniel; Zhang, Xiao-Long; /Fermilab

    2011-09-12

    Fermilab's Tevatron is currently the world's highest energy accelerator in which tightly focused beams of 980 GeV protons and antiprotons collide at two dedicated interaction points (IPs). Both beams share the same beam pipe and magnet aperture and, in order to avoid multiple detrimental head-on collisions, the beams are placed on separated orbits everywhere except the main IPs by using high-voltage (HV) electrostatic separators. The electromagnetic beam-beam interaction at the main IPs together with the long-range interactions between separated beams adversely affect the collider performance, reducing the luminosity integral per store (period of continuous collisions) by 10-30%. Tuning the collider operation for optimal performance becomes more and more cumbersome as the beam intensities and luminosity increase. The long-range effects which (besides being nonlinear) vary from bunch to bunch are particularly hard to mitigate. A comprehensive review of the beam-beam effects in the Tevatron Collider Run II can be found in Ref. [1]. The beam-beam effects have been the dominating sources of beam loss and lifetime limitations in the Tevatron proton-antiproton collider [1]. Electron lenses were originally proposed for compensation of electromagnetic long-range and head-on beam-beam interactions of proton and antiproton beams [2]. Results of successful employment of two electron lenses built and installed in the Tevatron are reported in [3,4,5]. In this paper we present design features of the Tevatron electron lenses (TELs), discuss the generation of electron beams, describe different modes of operation and outline the technical parameters of various subsystems.

  11. Designing and implementing a large-scale automated -80 degrees C archive.

    Science.gov (United States)

    Owen, Justin M; Woods, Peter

    2008-04-01

    This article describes an automated facility for storing biological samples at -80 degrees C, designed to meet the needs of The UK Biobank. No store of this size has previously used liquid nitrogen as refrigerant, and so it was important to confirm the storage compartments could achieve and maintain uniform conditions with efficient use of the coolant. In addition, the store incorporates a novel system of drawers designed to allow robotic access whilst maintaining storage conditions. Experiments were undertaken to prove the performance of both these factors in maintaining the temperature of stored samples, both in steady-state conditions and during sample access. Sample tubes containing water were placed in key locations within a prototype storage compartment. Thermocouples inside these sample tubes were used to together with automated data loggers to accumulate continuous records of the temperature of the samples during the experiments. Results show that the design of refrigeration system and storage compartment, using LN(2) as refrigerant, enables efficient use of coolant and maintains uniform temperature over the entire compartment. The results also show that samples within the compartment remain at the intended storage temperature during automated retrieval operations, including the situation when an access drawer remains open indefinitely. These results confirm that the store design meets the requirements for the UK Biobank, and have given both the manufacturer (The Automation Partnership) and the UK Biobank the confidence to proceed with the implementation of a full sized automated store to hold 10 million samples.

  12. Design of microcontroller based system for automation of streak camera.

    Science.gov (United States)

    Joshi, M J; Upadhyay, J; Deshpande, P P; Sharma, M L; Navathe, C P

    2010-08-01

    A microcontroller based system has been developed for automation of the S-20 optical streak camera, which is used as a diagnostic tool to measure ultrafast light phenomenon. An 8 bit MCS family microcontroller is employed to generate all control signals for the streak camera. All biasing voltages required for various electrodes of the tubes are generated using dc-to-dc converters. A high voltage ramp signal is generated through a step generator unit followed by an integrator circuit and is applied to the camera's deflecting plates. The slope of the ramp can be changed by varying values of the capacitor and inductor. A programmable digital delay generator has been developed for synchronization of ramp signal with the optical signal. An independent hardwired interlock circuit has been developed for machine safety. A LABVIEW based graphical user interface has been developed which enables the user to program the settings of the camera and capture the image. The image is displayed with intensity profiles along horizontal and vertical axes. The streak camera was calibrated using nanosecond and femtosecond lasers.

  13. Design of an Electronic Chest-Band

    Science.gov (United States)

    Atakan, R.; Acikgoz Tufan, H.; Baskan, H.; Eryuruk, S. H.; Akalin, N.; Kose, H.; Li, Y.; Kursun Bahadir, S.; Kalaoglu, F.

    2017-10-01

    In this study, an electronic chest strap prototype was designed for measuring fitness level, performance optimization, mobility and fall detection. Knitting technology is used for production by using highly elastic nylon yarn. In order to evaluate comfort performance of the garment, yarn strength and elongation, air permeability, moisture management and FAST tests (Fabric Assurance Fabric Testing) were carried out, respectively. After testing of textile part of the chest band, IMU sensors were integrated onto the garment by means of conductive yarns. Electrical conductivity of the circuit was also assessed at the end. Results indicated that the weight and the thickness of the product are relatively high for sports uses and it has a negative impact on comfort properties. However, it is highly stretchable and moisture management properties are still in acceptable values. From the perspective of possible application areas, developed smart chest band in this research could be used in sports facilities as well as health care applications for elderly and disabled people.

  14. Electronic cigarettes: product characterisation and design considerations.

    Science.gov (United States)

    Brown, Christopher J; Cheng, James M

    2014-05-01

    To review the available evidence regarding electronic cigarette (e-cigarette) product characterisation and design features in order to understand their potential impact on individual users and on public health. Systematic literature searches in 10 reference databases were conducted through October 2013. A total of 14 articles and documents and 16 patents were included in this analysis. Numerous disposable and reusable e-cigarette product options exist, representing wide variation in product configuration and component functionality. Common e-cigarette components include an aerosol generator, a flow sensor, a battery and a nicotine-containing solution storage area. e-cigarettes currently include many interchangeable parts, enabling users to modify the character of the delivered aerosol and, therefore, the product's 'effectiveness' as a nicotine delivery product. Materials in e-cigarettes may include metals, rubber and ceramics. Some materials may be aerosolised and have adverse health effects. Several studies have described significant performance variability across and within e-cigarette brands. Patent applications include novel product features designed to influence aerosol properties and e-cigarette efficiency at delivering nicotine. Although e-cigarettes share a basic design, engineering variations and user modifications result in differences in nicotine delivery and potential product risks. e-cigarette aerosols may include harmful and potentially harmful constituents. Battery explosions and the risks of exposure to the e-liquid (especially for children) are also concerns. Additional research will enhance the current understanding of basic e-cigarette design and operation, aerosol production and processing, and functionality. A standardised e-cigarette testing regime should be developed to allow product comparisons.

  15. AN AUTOMATED ANALYSIS-SYNTHESIS PACKAGE FOR DESIGN ...

    African Journals Online (AJOL)

    that are better than alternative designs with minimal illferaction and less computational effort. The capabilities of the package also include pure analysis and parametric studies. A 11umerical example will be prese11ted to show the pote11tial capabilities of the package. INTRODUCTION. Design in any engineering discipline ...

  16. An Automated Analysis-Synthesis Package for Design Optimization ...

    African Journals Online (AJOL)

    The package will enable the structural engineer to effectively and efficiently isolate designs that are better than alternative designs with minimal interaction and less computational effort. The capabilities of the package also include pure analysis and parametric studies. A numerical example will be presented to show the ...

  17. Design Automation Using Script Languages. High-Level CAD Templates in Non-Parametric Programs

    Science.gov (United States)

    Moreno, R.; Bazán, A. M.

    2017-10-01

    The main purpose of this work is to study the advantages offered by the application of traditional techniques of technical drawing in processes for automation of the design, with non-parametric CAD programs, provided with scripting languages. Given that an example drawing can be solved with traditional step-by-step detailed procedures, is possible to do the same with CAD applications and to generalize it later, incorporating references. In today’s modern CAD applications, there are striking absences of solutions for building engineering: oblique projections (military and cavalier), 3D modelling of complex stairs, roofs, furniture, and so on. The use of geometric references (using variables in script languages) and their incorporation into high-level CAD templates allows the automation of processes. Instead of repeatedly creating similar designs or modifying their data, users should be able to use these templates to generate future variations of the same design. This paper presents the automation process of several complex drawing examples based on CAD script files aided with parametric geometry calculation tools. The proposed method allows us to solve complex geometry designs not currently incorporated in the current CAD applications and to subsequently create other new derivatives without user intervention. Automation in the generation of complex designs not only saves time but also increases the quality of the presentations and reduces the possibility of human errors.

  18. Failure mode and effect analysis oriented to risk-reduction interventions in intraoperative electron radiation therapy: the specific impact of patient transportation, automation, and treatment planning availability

    National Research Council Canada - National Science Library

    López-Tarjuelo, Juan; Bouché-Babiloni, Ana; Santos-Serra, Agustín; Morillo-Macías, Virginia; Calvo, Felipe A; Kubyshin, Yuri; Ferrer-Albiach, Carlos

    2014-01-01

    Industrial companies use failure mode and effect analysis (FMEA) to improve quality. Our objective was to describe an FMEA and subsequent interventions for an automated intraoperative electron radiotherapy...

  19. Automated Design and Evaluation of Airfoils for Rotorcraft Applications

    Science.gov (United States)

    2017-12-01

    orthogonal decomposition for aero- dynamic design optimization,” AIAA journal , 48(5), pp. 916–928. [6] Kulfan, B. M. (2008) “Universal parametric...recent developments in rotorcraft design optimization,” Journal of Aircraft, 41(3), pp. 493–510. [15] Saberi, H., M. Khoshlahjeh, R. A. Ormiston, and M. J...applied to the aerodynamic design of transonic airfoils,” Journal of aircraft, 32(4), pp. 889–891. [28] Jones, B. R., W. A. Crossley, and A. S. Lyrintzis

  20. GeNeDA: An Open-Source Workflow for Design Automation of Gene Regulatory Networks Inspired from Microelectronics.

    Science.gov (United States)

    Madec, Morgan; Pecheux, François; Gendrault, Yves; Rosati, Elise; Lallement, Christophe; Haiech, Jacques

    2016-10-01

    The topic of this article is the development of an open-source automated design framework for synthetic biology, specifically for the design of artificial gene regulatory networks based on a digital approach. In opposition to other tools, GeNeDA is an open-source online software based on existing tools used in microelectronics that have proven their efficiency over the last 30 years. The complete framework is composed of a computation core directly adapted from an Electronic Design Automation tool, input and output interfaces, a library of elementary parts that can be achieved with gene regulatory networks, and an interface with an electrical circuit simulator. Each of these modules is an extension of microelectronics tools and concepts: ODIN II, ABC, the Verilog language, SPICE simulator, and SystemC-AMS. GeNeDA is first validated on a benchmark of several combinatorial circuits. The results highlight the importance of the part library. Then, this framework is used for the design of a sequential circuit including a biological state machine.

  1. Automated Computational Fluid Dynamics Design With Shape Optimization Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Computational fluid dynamics (CFD) is used as an analysis tool to help the designer gain greater understanding of the fluid flow phenomena involved in the components...

  2. Automation for pattern library creation and in-design optimization

    Science.gov (United States)

    Deng, Rock; Zou, Elain; Hong, Sid; Wang, Jinyan; Zhang, Yifan; Sweis, Jason; Lai, Ya-Chieh; Ding, Hua; Huang, Jason

    2015-03-01

    Semiconductor manufacturing technologies are becoming increasingly complex with every passing node. Newer technology nodes are pushing the limits of optical lithography and requiring multiple exposures with exotic material stacks for each critical layer. All of this added complexity usually amounts to further restrictions in what can be designed. Furthermore, the designs must be checked against all these restrictions in verification and sign-off stages. Design rules are intended to capture all the manufacturing limitations such that yield can be maximized for any given design adhering to all the rules. Most manufacturing steps employ some sort of model based simulation which characterizes the behavior of each step. The lithography models play a very big part of the overall yield and design restrictions in patterning. However, lithography models are not practical to run during design creation due to their slow and prohibitive run times. Furthermore, the models are not usually given to foundry customers because of the confidential and sensitive nature of every foundry's processes. The design layout locations where a model flags unacceptable simulated results can be used to define pattern rules which can be shared with customers. With advanced technology nodes we see a large growth of pattern based rules. This is due to the fact that pattern matching is very fast and the rules themselves can be very complex to describe in a standard DRC language. Therefore, the patterns are left as either pattern layout clips or abstracted into pattern-like syntax which a pattern matcher can use directly. The patterns themselves can be multi-layered with "fuzzy" designations such that groups of similar patterns can be found using one description. The pattern matcher is often integrated with a DRC tool such that verification and signoff can be done in one step. The patterns can be layout constructs that are "forbidden", "waived", or simply low-yielding in nature. The patterns can also

  3. Designing an Automated Assessment of Public Speaking Skills Using Multimodal Cues

    Science.gov (United States)

    Chen, Lei; Feng, Gary; Leong, Chee Wee; Joe, Jilliam; Kitchen, Christopher; Lee, Chong Min

    2016-01-01

    Traditional assessments of public speaking skills rely on human scoring. We report an initial study on the development of an automated scoring model for public speaking performances using multimodal technologies. Task design, rubric development, and human rating were conducted according to standards in educational assessment. An initial corpus of…

  4. Scar-less multi-part DNA assembly design automation

    Science.gov (United States)

    Hillson, Nathan J.

    2016-06-07

    The present invention provides a method of a method of designing an implementation of a DNA assembly. In an exemplary embodiment, the method includes (1) receiving a list of DNA sequence fragments to be assembled together and an order in which to assemble the DNA sequence fragments, (2) designing DNA oligonucleotides (oligos) for each of the DNA sequence fragments, and (3) creating a plan for adding flanking homology sequences to each of the DNA oligos. In an exemplary embodiment, the method includes (1) receiving a list of DNA sequence fragments to be assembled together and an order in which to assemble the DNA sequence fragments, (2) designing DNA oligonucleotides (oligos) for each of the DNA sequence fragments, and (3) creating a plan for adding optimized overhang sequences to each of the DNA oligos.

  5. Automated Verification of Design Patterns with LePUS3

    Science.gov (United States)

    Nicholson, Jonathan; Gasparis, Epameinondas; Eden, Ammon H.; Kazman, Rick

    2009-01-01

    Specification and [visual] modelling languages are expected to combine strong abstraction mechanisms with rigour, scalability, and parsimony. LePUS3 is a visual, object-oriented design description language axiomatized in a decidable subset of the first-order predicate logic. We demonstrate how LePUS3 is used to formally specify a structural design pattern and prove ( verify ) whether any JavaTM 1.4 program satisfies that specification. We also show how LePUS3 specifications (charts) are composed and how they are verified fully automatically in the Two-Tier Programming Toolkit.

  6. Automated design of programmable enzyme-driven DNA circuits

    NARCIS (Netherlands)

    van Roekel, Hendrik W.H.; Meijer, Lenny H.H.; Masroor, Saeed; Félix Garza, Zandra C.; Estévez-Torres, André; Rondelez, Yannick; Zagaris, Antonios; Peletier, Mark A.; Hilbers, Peter A.J.; de Greef, Tom F.A.

    2015-01-01

    Molecular programming allows for the bottom-up engineering of biochemical reaction networks in a controlled in vitro setting. These engineered biochemical reaction networks yield important insight in the design principles of biological systems and can potentially enrich molecular diagnostic systems.

  7. Automated Control Surface Design and Sizing for the Prandtl Plane

    NARCIS (Netherlands)

    Van Ginneken, D.A.J.; Voskuijl, M.; Van Tooren, M.J.L.; Frediani, A.

    2010-01-01

    This paper presents a methodology for the design of the primary flight control surfaces, in terms of size, number and location, for fixed wing aircraft (conventional or unconventional). As test case, the methodology is applied to a 300 passenger variant of the Prandtl Plane. This box wing aircraft

  8. Automated Design of Board and MCM Level Digital Systems.

    Science.gov (United States)

    1997-10-01

    Peter Sestoft. Partial Evaluation and Automatic Program Generation. Prentice Hall, Englewood Cliffs, N.J., 1993. [6] R.E. Bryant. "Can a Simulator... ASHENDEN , P. The Designers Guide to VHDL. Morgan Kaufmann Publishers, Inc, San Mateo, CAj 1996. 33 279 [6] AUGUSTIN, L., LUCKHAM, D., GENNART, B., HUH, Y

  9. Design for additive manufacturing: Automated build orientation selection and optimization

    NARCIS (Netherlands)

    Zwier, Marijn Pieter; Wits, Wessel Willems

    2016-01-01

    Additive manufacturing, or 3D printing, is an emerging type of production technology that is seen as the core technology for future high-value engineered products. Due to the additive nature of stacking and unifying individual layers, the part and process design is substantially different from

  10. Parameter Studies, time-dependent simulations and design with automated Cartesian methods

    Science.gov (United States)

    Aftosmis, Michael

    2005-01-01

    Over the past decade, NASA has made a substantial investment in developing adaptive Cartesian grid methods for aerodynamic simulation. Cartesian-based methods played a key role in both the Space Shuttle Accident Investigation and in NASA's return to flight activities. The talk will provide an overview of recent technological developments focusing on the generation of large-scale aerodynamic databases, automated CAD-based design, and time-dependent simulations with of bodies in relative motion. Automation, scalability and robustness underly all of these applications and research in each of these topics will be presented.

  11. Design of a robotic automation system for transportation of goods in hospitals

    DEFF Research Database (Denmark)

    Özkil, Ali Gürcan; Sørensen, Torben; Fan, Zhun

    2007-01-01

    Hospitals face with heavy traffic of goods everyday, where transportation tasks are mainly carried by human. Analysis of the current situation of transportation in a typical hospital showed several transportation tasks are suitable for automation. This paper presents a system, consisting of a fleet...... of robot vehicles, automatic stations and smart containers for automation of transportation of goods in hospitals. Design of semi-autonomous robot vehicles, containers and stations are presented and the overall system architecture is described. Implementing such a system in an existing hospital showed...

  12. Performance Evaluation of a Software Engineering Tool for Automated Design of Cooling Systems in Injection Moulding

    DEFF Research Database (Denmark)

    Jauregui-Becker, Juan M.; Tosello, Guido; van Houten, Fred J.A.M.

    2013-01-01

    This paper presents a software tool for automating the design of cooling systems for injection moulding and a validation of its performance. Cooling system designs were automatically generated by the proposed software tool and by applying a best practice tool engineering design approach. The two...... different design methods (i.e. automatic and manual) were applied to the mould design of two thin-walled products, namely a rectangular flat box and a cylindrical container with a flat base. Injection moulding process simulations based on the finite element method were performed to assess the quality...

  13. Automation at home : a design process for social low

    Directory of Open Access Journals (Sweden)

    Boris Andrés Quintana G.

    2015-07-01

    Full Text Available Rev.esc.adm.neg This article aims at showing a research study based on the development of a system used to support social low cost houses by using domotic systems. Through time, these systems have been designed for wealthy people without taking into account environmental and social responsibility in their manufacturing and installation. For this reason, a serious research was done to identify the factors which raise cost, trying to execute domotic projects in low cost houses to finally implement energetic self- generation technologies for the design and manufacturing of objects which contribute to make people conscious about energetic waste and the economic development of this low social class groups. Consequently, this research study not only involved scientific investigation but also field work, which will be described in this paper aiming at showing the above mentioned system for this social group.

  14. 3D RFID Simulation and Design - Factory Automation

    OpenAIRE

    Liu, Wei; Wong, Ming Mao

    2010-01-01

    This chapter has presented and investigated loop antenna and sensor circuit for HF RFID smart shelf application. The issues including tag orientations, read range, proximity of metal and other antennas are approached during the antenna design. A 3-dimensional shape of single turn loop antenna is proposed. The optimum antenna size was determined as a trade-off between the magnetic field strength and mechanical constraint. The antenna model has been successfully used to configure an HF RFID sma...

  15. Exploiting design patterns to automate validation of class invariants

    OpenAIRE

    Malloy, Brian A.; Power, James F.

    2006-01-01

    In this paper, techniques are presented that exploit two design patterns, the Visitor pattern and the Decorator pattern, to automatically validate invariants about the data attributes in a C++ class. To investigate the pragmatics involved in using the two patterns, a study of an existing, well-tested application, keystone, a parser and frontend for the C++ language, is presented. Results from the study indicate that these two patterns provide flexibility in terms of the frequen...

  16. ASPHERICAL SURFACES APPROXIMATION IN AUTOMATED DESIGN OF OPTICAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    T. V. Ivanova

    2015-07-01

    Full Text Available Subject of Research. The paper deals with the problems of higher order aspherical surfaces approximation using different equation types. The objects of research are two types of equations for higher order aspherical surfaces description used in different software for optical systems design (SАRО, OPAL, ZEMAX, CODE-V, etc. and dependent on z-coordinate or on a radial coordinate on the surface. Conversion from one type of equations to another is considered in view of application in different software for optical systems design. Methods. The subject matter of the method lies in usage of mean square method approximation for recalculation of high-order aspherical surface. Iterative algorithm for recalculation is presented giving the possibility to recalculate coefficients for different types of equations with required accuracy. Recommendations are given for choosing recalculation parameters such as the number of result equation coefficients, the number of points for recalculation and point allocation on a surface. Main Results. Example of recalculation for aspherical surface and accuracy estimation, including result aberration comparison between initial surface and recalculated surface are presented. The example has shown that required accuracy of surface representation was obtained. Practical Relevance. This technique is usable for recalculation of higher order aspherical surfaces in various types of software for optical systems design and also for research of optimal higher order aspherical surfaces description.

  17. Design of a Screen Based Simulation for Training and Automated Assessment of Teamwork Skills

    Science.gov (United States)

    2017-08-01

    scenarios include the same basic and advanced teamwork skills , including conflict resolution (under leadership and mutual support).  Major Task 3. Design...21  Introduces self to other team members (1a, 2a) Elicits or knows skills of various team members (1a & 1c) 1. Leadership Establishes himself or...AWARD NUMBER: W81XWH-16-1-0308 TITLE: Design of a Screen-Based Simulation for Training and Automated Assessment of Teamwork Skills PRINCIPAL

  18. A clinical trial comparing physician prompting with an unprompted automated electronic checklist to reduce empirical antibiotic utilization.

    Science.gov (United States)

    Weiss, Curtis H; Dibardino, David; Rho, Jason; Sung, Nina; Collander, Brett; Wunderink, Richard G

    2013-11-01

    To determine whether face-to-face prompting of critical care physicians reduces empirical antibiotic utilization compared to an unprompted electronic checklist embedded within the electronic health record. Random allocation design. Medical ICU with high-intensity intensivist coverage at a tertiary care urban medical center. Two hundred ninety-six critically ill patients treated with at least 1 day of empirical antibiotics. For one medical ICU team, face-to-face prompting of critical care physicians if they did not address empirical antibiotic utilization during a patient's daily rounds. On a separate medical ICU team, attendings and fellows were trained once to complete an electronic health record-embedded checklist daily for each patient, including a question asking whether listed empirical antibiotics could be discontinued. Prompting led to a more than four-fold increase in discontinuing or narrowing of empirical antibiotics compared to use of the electronic checklist. Prompted group patients had a lower proportion of patient-days on which empirical antibiotics were administered compared to electronic checklist group patients (63.1% vs 70.0%, p = 0.002). Mean proportion of antibiotic-days on which empirical antibiotics were used was also lower in the prompted group, although not statistically significant (0.78 [0.27] vs 0.83 [0.27], p = 0.093). Each additional day of empirical antibiotics predicted higher risk-adjusted mortality (odds ratio, 1.14; 95% CI, 1.05-1.23). Risk-adjusted ICU length of stay and hospital mortality were not significantly different between the two groups. Face-to-face prompting was superior to an unprompted electronic health record-based checklist at reducing empirical antibiotic utilization. Sustained culture change may have contributed to the electronic checklist having similar empirical antibiotic utilization to a prompted group in the same medical ICU 2 years prior. Future studies should investigate the integration of an automated

  19. Design principles and algorithms for automated air traffic management

    Science.gov (United States)

    Erzberger, Heinz

    1995-01-01

    This paper presents design principles and algorithm for building a real time scheduler. The primary objective of the scheduler is to assign arrival aircraft to a favorable landing runway and schedule them to land at times that minimize delays. A further objective of the scheduler is to allocate delays between high altitude airspace far from the airport and low altitude airspace near the airport. A method of delay allocation is described that minimizes the average operating cost in the presence of errors in controlling aircraft to a specified landing time.

  20. New hardware and workflows for semi-automated correlative cryo-fluorescence and cryo-electron microscopy/tomography.

    Science.gov (United States)

    Schorb, Martin; Gaechter, Leander; Avinoam, Ori; Sieckmann, Frank; Clarke, Mairi; Bebeacua, Cecilia; Bykov, Yury S; Sonnen, Andreas F-P; Lihl, Reinhard; Briggs, John A G

    2017-02-01

    Correlative light and electron microscopy allows features of interest defined by fluorescence signals to be located in an electron micrograph of the same sample. Rare dynamic events or specific objects can be identified, targeted and imaged by electron microscopy or tomography. To combine it with structural studies using cryo-electron microscopy or tomography, fluorescence microscopy must be performed while maintaining the specimen vitrified at liquid-nitrogen temperatures and in a dry environment during imaging and transfer. Here we present instrumentation, software and an experimental workflow that improves the ease of use, throughput and performance of correlated cryo-fluorescence and cryo-electron microscopy. The new cryo-stage incorporates a specially modified high-numerical aperture objective lens and provides a stable and clean imaging environment. It is combined with a transfer shuttle for contamination-free loading of the specimen. Optimized microscope control software allows automated acquisition of the entire specimen area by cryo-fluorescence microscopy. The software also facilitates direct transfer of the fluorescence image and associated coordinates to the cryo-electron microscope for subsequent fluorescence-guided automated imaging. Here we describe these technological developments and present a detailed workflow, which we applied for automated cryo-electron microscopy and tomography of various specimens. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  1. Surrogate-Assisted Genetic Programming With Simplified Models for Automated Design of Dispatching Rules.

    Science.gov (United States)

    Nguyen, Su; Zhang, Mengjie; Tan, Kay Chen

    2017-09-01

    Automated design of dispatching rules for production systems has been an interesting research topic over the last several years. Machine learning, especially genetic programming (GP), has been a powerful approach to dealing with this design problem. However, intensive computational requirements, accuracy and interpretability are still its limitations. This paper aims at developing a new surrogate assisted GP to help improving the quality of the evolved rules without significant computational costs. The experiments have verified the effectiveness and efficiency of the proposed algorithms as compared to those in the literature. Furthermore, new simplification and visualisation approaches have also been developed to improve the interpretability of the evolved rules. These approaches have shown great potentials and proved to be a critical part of the automated design system.

  2. A new frontier in synthetic biology: automated design of small RNA devices in bacteria.

    Science.gov (United States)

    Rodrigo, Guillermo; Landrain, Thomas E; Shen, Shensi; Jaramillo, Alfonso

    2013-09-01

    RNA devices provide synthetic biologists with tools for manipulating post-transcriptional regulation and conditional detection of cellular biomolecules. The use of computational methods to design RNA devices has improved to the stage where it is now possible to automate the entire design process. These methods utilize structure prediction tools that optimize nucleotide sequences, together with fragments of known independent functionalities. Recently, this approach has been used to create an automated method for the de novo design of riboregulators. Here, we describe how it is possible to obtain riboregulatory circuits in prokaryotes by capturing the relevant interactions of RNAs inside the cytoplasm using a physicochemical model. We focus on the regulation of protein expression mediated by intra- or intermolecular interactions of small RNAs (sRNAs), and discuss the design of riboregulators for other functions. The automated design of RNA devices opens new possibilities for engineering fully synthetic regulatory systems that program new functions or reprogram dysfunctions in living cells. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. On the design and implementation of an automated astronomical image analyzer

    Science.gov (United States)

    Zhao, Lei; Sharif, Gabe; Orellana, Sonny; Boussalis, Helen; Liu, Charles; Rad, Khosrow; Dong, Jane

    2006-10-01

    Sponsored by the National Aeronautical Space Association (NASA), the Synergetic Education and Research in Enabling NASA-centered Academic Development of Engineers and Space Scientists (SERENADES) Laboratory was established at California State University, Los Angeles (CSULA). An important on-going research activity in this lab is to develop an easy-to-use image analysis software with the capability of automated object detection to facilitate astronomical research. This paper presents the design and implementation of an automated astronomical image analyzer. The core of this software is the automated object detection algorithm developed in our previous research, which is capable of detecting objects in near galaxy images, including objects located within clouds. In addition to the functionality, human factor is considered in system design and tremendous efforts have been devoted to enhance the user friendliness. Instead of using command line or static menus, graphical methods are enabled in our software system to allow the user to directly manipulate the objects that he/she wants to investigate. Comprehensive tests are conducted by users with and without astronomical backgrounds. Compared to current software tools such as IRAF and Skyview, our developed software has the following advantages: 1) No pre-training is required; 2) The amount of human supervision is significantly reduced by automated object detection; 3) Batch processing capability is supported for fast operation; and 4) A high degree of human computer interaction is realized for better usability.

  4. Electronic-Power-Transformer Design Guide

    Science.gov (United States)

    Schwarze, G. E.; Lagadinos, J. C.; Ahearn, J. F.

    1983-01-01

    Compilation of information on design procedures, electrical properties, and fabrication. Guide provides information on design procedures; magnetic and insulating material electrical properties; impregnating, encapsulating and processing techniques.

  5. Automated detection of synapses in serial section transmission electron microscopy image stacks.

    Directory of Open Access Journals (Sweden)

    Anna Kreshuk

    Full Text Available We describe a method for fully automated detection of chemical synapses in serial electron microscopy images with highly anisotropic axial and lateral resolution, such as images taken on transmission electron microscopes. Our pipeline starts from classification of the pixels based on 3D pixel features, which is followed by segmentation with an Ising model MRF and another classification step, based on object-level features. Classifiers are learned on sparse user labels; a fully annotated data subvolume is not required for training. The algorithm was validated on a set of 238 synapses in 20 serial 7197×7351 pixel images (4.5×4.5×45 nm resolution of mouse visual cortex, manually labeled by three independent human annotators and additionally re-verified by an expert neuroscientist. The error rate of the algorithm (12% false negative, 7% false positive detections is better than state-of-the-art, even though, unlike the state-of-the-art method, our algorithm does not require a prior segmentation of the image volume into cells. The software is based on the ilastik learning and segmentation toolkit and the vigra image processing library and is freely available on our website, along with the test data and gold standard annotations (http://www.ilastik.org/synapse-detection/sstem.

  6. Automated detection of synapses in serial section transmission electron microscopy image stacks.

    Science.gov (United States)

    Kreshuk, Anna; Koethe, Ullrich; Pax, Elizabeth; Bock, Davi D; Hamprecht, Fred A

    2014-01-01

    We describe a method for fully automated detection of chemical synapses in serial electron microscopy images with highly anisotropic axial and lateral resolution, such as images taken on transmission electron microscopes. Our pipeline starts from classification of the pixels based on 3D pixel features, which is followed by segmentation with an Ising model MRF and another classification step, based on object-level features. Classifiers are learned on sparse user labels; a fully annotated data subvolume is not required for training. The algorithm was validated on a set of 238 synapses in 20 serial 7197×7351 pixel images (4.5×4.5×45 nm resolution) of mouse visual cortex, manually labeled by three independent human annotators and additionally re-verified by an expert neuroscientist. The error rate of the algorithm (12% false negative, 7% false positive detections) is better than state-of-the-art, even though, unlike the state-of-the-art method, our algorithm does not require a prior segmentation of the image volume into cells. The software is based on the ilastik learning and segmentation toolkit and the vigra image processing library and is freely available on our website, along with the test data and gold standard annotations (http://www.ilastik.org/synapse-detection/sstem).

  7. Automating Quality Metrics in the Era of Electronic Medical Records: Digital Signatures for Ventilator Bundle Compliance.

    Science.gov (United States)

    Lan, Haitao; Thongprayoon, Charat; Ahmed, Adil; Herasevich, Vitaly; Sampathkumar, Priya; Gajic, Ognjen; O'Horo, John C

    2015-01-01

    Ventilator-associated events (VAEs) are associated with increased risk of poor outcomes, including death. Bundle practices including thromboembolism prophylaxis, stress ulcer prophylaxis, oral care, and daily sedation breaks and spontaneous breathing trials aim to reduce rates of VAEs and are endorsed as quality metrics in the intensive care units. We sought to create electronic search algorithms (digital signatures) to evaluate compliance with ventilator bundle components as the first step in a larger project evaluating the ventilator bundle effect on VAE. We developed digital signatures of bundle compliance using a retrospective cohort of 542 ICU patients from 2010 for derivation and validation and testing of signature accuracy from a cohort of random 100 patients from 2012. Accuracy was evaluated against manual chart review. Overall, digital signatures performed well, with median sensitivity of 100% (range, 94.4%-100%) and median specificity of 100% (range, 100%-99.8%). Automated ascertainment from electronic medical records accurately assesses ventilator bundle compliance and can be used for quality reporting and research in VAE.

  8. Passivity-Based Automated Design of Stable Multi-Feedback Distributed Power Delivery Systems

    Science.gov (United States)

    2017-03-01

    performan pically determ C gain, phase stributed on- delivering hig ce systems. S n automated delivery is pr is designe fabricated in performance a n-chip...termined by t In systems w igure 1, the se no straig table loop. An een proposed the power g design proces this work b on with a pa iques...Performan ce of an i ined by a se margin, DC o chip power h quality pow tability is a pr design flow f oposed. A dis d based on 28 nm CMO nd stable

  9. MEMS/Electronic Device Design and Characterization Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility allows DoD to design and characterize state-of-the-art microelectromechanical systems (MEMS) and electronic devices. Device designers develop their own...

  10. Designing for acceptance : Exchange design for electronic intermediaries

    NARCIS (Netherlands)

    Fielt, E.J.

    2006-01-01

    Electronic business has brought many success stories as well as failures. Intermediaries are a particularly interesting application domain: on the one hand, they are given opportunities by electronic business to reinvent their value logic, while on the other they are threatened by opportunities for

  11. Automated design of IoT Wi-Fi FSS filter

    Directory of Open Access Journals (Sweden)

    Tomasek Pavel

    2016-01-01

    Full Text Available This work is presenting a technique of automated design of a Frequency Selective Surface aimed at shielding wireless communication under a very new standard of IEEE 802.11ah. This standard is primarily focused on rapidly growing network of communicating electrical devices called Internet of Things. Shielding of such a communication can be, in certain situations, very important for elimination of the possibility of eavesdropping.

  12. Reliable design of electronic equipment an engineering guide

    CERN Document Server

    Natarajan, Dhanasekharan

    2014-01-01

    This book explains reliability techniques with examples from electronics design for the benefit of engineers. It presents the application of de-rating, FMEA, overstress analyses and reliability improvement tests for designing reliable electronic equipment. Adequate information is provided for designing computerized reliability database system to support the application of the techniques by designers. Pedantic terms and the associated mathematics of reliability engineering discipline are excluded for the benefit of comprehensiveness and practical applications. This book offers excellent support

  13. Research and Design on Navigation Electronic Map System

    Directory of Open Access Journals (Sweden)

    Xiaotong Yang

    2013-07-01

    Full Text Available This paper puts forward the new definition on the basis of the original concept of the navigation electronic map, designs the structure of the navigation electronic map system which contains three parts: hardware equipment, data system and software system, and analyzes each part of them in detail, finally this paper discusses the functional framework of the navigation electronic map.

  14. Automated Design of Propellant-Optimal, End-to-End, Low-Thrust Trajectories for Trojan Asteroid Tours

    Science.gov (United States)

    Stuart, Jeffrey; Howell, Kathleen; Wilson, Roby

    2013-01-01

    The Sun-Jupiter Trojan asteroids are celestial bodies of great scientific interest as well as potential resources offering water and other mineral resources for longterm human exploration of the solar system. Previous investigations under this project have addressed the automated design of tours within the asteroid swarm. This investigation expands the current automation scheme by incorporating options for a complete trajectory design approach to the Trojan asteroids. Computational aspects of the design procedure are automated such that end-to-end trajectories are generated with a minimum of human interaction after key elements and constraints associated with a proposed mission concept are specified.

  15. Structure Optimization Design of the Electronically Controlled Fuel Control Rod System in a Diesel Engine

    Directory of Open Access Journals (Sweden)

    Hui Jin

    2015-01-01

    Full Text Available Poor ride comfort and shorter clutch life span are the key factors restricting the commercialization of automated manual transmission (AMT. For nonelectrically controlled engines or AMT where cooperative control between the engine and the transmission is not realizable, applying electronically controlled fuel control rod systems (ECFCRS is an effective way to solve these problems. By applying design software such as CATIA, Matlab and Simulink, and MSC Adams, a suite of optimization design methods for ECFCRS drive mechanisms are developed here. Based on these new methods, design requirements can be analyzed comprehensively and the design scheme can be modified easily, thus greatly shortening the design cycle. The bench tests and real vehicle tests indicate that the system developed achieves preferable engine speed following-up performance and engine speed regulating performance. The method developed has significance as a reference for developing other vehicle systems.

  16. Ankle-Foot Orthosis Made by 3D Printing Technique and Automated Design Software

    Science.gov (United States)

    Cha, Yong Ho; Lee, Keun Ho; Ryu, Hong Jong; Joo, Il Won; Seo, Anna; Kim, Dong-Hyeon

    2017-01-01

    We described 3D printing technique and automated design software and clinical results after the application of this AFO to a patient with a foot drop. After acquiring a 3D modelling file of a patient's lower leg with peroneal neuropathy by a 3D scanner, we loaded this file on the automated orthosis software and created the “STL” file. The designed AFO was printed using a fused filament fabrication type 3D printer, and a mechanical stress test was performed. The patient alternated between the 3D-printed and conventional AFOs for 2 months. There was no crack or damage, and the shape and stiffness of the AFO did not change after the durability test. The gait speed increased after wearing the conventional AFO (56.5 cm/sec) and 3D-printed AFO (56.5 cm/sec) compared to that without an AFO (42.2 cm/sec). The patient was more satisfied with the 3D-printed AFO than the conventional AFO in terms of the weight and ease of use. The 3D-printed AFO exhibited similar functionality as the conventional AFO and considerably satisfied the patient in terms of the weight and ease of use. We suggest the possibility of the individualized AFO with 3D printing techniques and automated design software. PMID:28827977

  17. Ankle-Foot Orthosis Made by 3D Printing Technique and Automated Design Software

    Directory of Open Access Journals (Sweden)

    Yong Ho Cha

    2017-01-01

    Full Text Available We described 3D printing technique and automated design software and clinical results after the application of this AFO to a patient with a foot drop. After acquiring a 3D modelling file of a patient’s lower leg with peroneal neuropathy by a 3D scanner, we loaded this file on the automated orthosis software and created the “STL” file. The designed AFO was printed using a fused filament fabrication type 3D printer, and a mechanical stress test was performed. The patient alternated between the 3D-printed and conventional AFOs for 2 months. There was no crack or damage, and the shape and stiffness of the AFO did not change after the durability test. The gait speed increased after wearing the conventional AFO (56.5 cm/sec and 3D-printed AFO (56.5 cm/sec compared to that without an AFO (42.2 cm/sec. The patient was more satisfied with the 3D-printed AFO than the conventional AFO in terms of the weight and ease of use. The 3D-printed AFO exhibited similar functionality as the conventional AFO and considerably satisfied the patient in terms of the weight and ease of use. We suggest the possibility of the individualized AFO with 3D printing techniques and automated design software.

  18. Ankle-Foot Orthosis Made by 3D Printing Technique and Automated Design Software.

    Science.gov (United States)

    Cha, Yong Ho; Lee, Keun Ho; Ryu, Hong Jong; Joo, Il Won; Seo, Anna; Kim, Dong-Hyeon; Kim, Sang Jun

    2017-01-01

    We described 3D printing technique and automated design software and clinical results after the application of this AFO to a patient with a foot drop. After acquiring a 3D modelling file of a patient's lower leg with peroneal neuropathy by a 3D scanner, we loaded this file on the automated orthosis software and created the "STL" file. The designed AFO was printed using a fused filament fabrication type 3D printer, and a mechanical stress test was performed. The patient alternated between the 3D-printed and conventional AFOs for 2 months. There was no crack or damage, and the shape and stiffness of the AFO did not change after the durability test. The gait speed increased after wearing the conventional AFO (56.5 cm/sec) and 3D-printed AFO (56.5 cm/sec) compared to that without an AFO (42.2 cm/sec). The patient was more satisfied with the 3D-printed AFO than the conventional AFO in terms of the weight and ease of use. The 3D-printed AFO exhibited similar functionality as the conventional AFO and considerably satisfied the patient in terms of the weight and ease of use. We suggest the possibility of the individualized AFO with 3D printing techniques and automated design software.

  19. Power Electronic Packaging Design, Assembly Process, Reliability and Modeling

    CERN Document Server

    Liu, Yong

    2012-01-01

    Power Electronic Packaging presents an in-depth overview of power electronic packaging design, assembly,reliability and modeling. Since there is a drastic difference between IC fabrication and power electronic packaging, the book systematically introduces typical power electronic packaging design, assembly, reliability and failure analysis and material selection so readers can clearly understand each task's unique characteristics. Power electronic packaging is one of the fastest growing segments in the power electronic industry, due to the rapid growth of power integrated circuit (IC) fabrication, especially for applications like portable, consumer, home, computing and automotive electronics. This book also covers how advances in both semiconductor content and power advanced package design have helped cause advances in power device capability in recent years. The author extrapolates the most recent trends in the book's areas of focus to highlight where further improvement in materials and techniques can d...

  20. Automated discrete electron tomography – Towards routine high-fidelity reconstruction of nanomaterials

    Energy Technology Data Exchange (ETDEWEB)

    Zhuge, Xiaodong [Computational Imaging, Centrum Wiskunde & Informatica, Science park 123, 1098XG Amsterdam (Netherlands); Jinnai, Hiroshi [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, Katahira 2-1-1, Aoba-ku, Sendai 980-8577 (Japan); Dunin-Borkowski, Rafal E.; Migunov, Vadim [Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons and Peter Grünberg Institute, Forschungszentrum Jülich, D-52425 Jülich (Germany); Bals, Sara [EMAT, University of Antwerp, Groenenborgerlaan 171, B-2020 Antwerp (Belgium); Cool, Pegie [Laboratory of Adsorption and Catalysis, Department of Chemistry, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk (Belgium); Bons, Anton-Jan [European Technology Center, ExxonMobil Chemical Europe Inc., Hermeslaan 2, B-1831 Machelen (Belgium); Batenburg, Kees Joost [Computational Imaging, Centrum Wiskunde & Informatica, Science park 123, 1098XG Amsterdam (Netherlands)

    2017-04-15

    Electron tomography is an essential imaging technique for the investigation of morphology and 3D structure of nanomaterials. This method, however, suffers from well-known missing wedge artifacts due to a restricted tilt range, which limits the objectiveness, repeatability and efficiency of quantitative structural analysis. Discrete tomography represents one of the promising reconstruction techniques for materials science, potentially capable of delivering higher fidelity reconstructions by exploiting the prior knowledge of the limited number of material compositions in a specimen. However, the application of discrete tomography to practical datasets remains a difficult task due to the underlying challenging mathematical problem. In practice, it is often hard to obtain consistent reconstructions from experimental datasets. In addition, numerous parameters need to be tuned manually, which can lead to bias and non-repeatability. In this paper, we present the application of a new iterative reconstruction technique, named TVR-DART, for discrete electron tomography. The technique is capable of consistently delivering reconstructions with significantly reduced missing wedge artifacts for a variety of challenging data and imaging conditions, and can automatically estimate its key parameters. We describe the principles of the technique and apply it to datasets from three different types of samples acquired under diverse imaging modes. By further reducing the available tilt range and number of projections, we show that the proposed technique can still produce consistent reconstructions with minimized missing wedge artifacts. This new development promises to provide the electron microscopy community with an easy-to-use and robust tool for high-fidelity 3D characterization of nanomaterials. - Highlights: • Automated discrete electron tomography capable of consistently delivering reconstructions with significantly reduced missing wedge artifacts and requires significantly

  1. Implementing a WLAN Video Terminal Using UML and Fully Automated Design Flow

    Directory of Open Access Journals (Sweden)

    Petri Kukkala

    2007-03-01

    Full Text Available This case study presents UML-based design and implementation of a wireless video terminal on a multiprocessor system-on-chip (SoC. The terminal comprises video encoder and WLAN communications subsystems. In this paper, we present the UML models used in designing the functionality of the subsystems as well as the architecture of the terminal hardware. We use the Koski design flow and tools for fully automated implementation of the terminal on FPGA. Measurements were performed to evaluate the performance of the FPGA implementation. Currently, fully software encoder achieves the frame rate of 3.0 fps with three 50 MHz processors, which is one half of a reference C implementation. Thus, using UML and design automation reduces the performance, but we argue that this is highly accepted as we gain significant improvement in design efficiency and flexibility. The experiments with the UML-based design flow proved its suitability and competence in designing complex embedded multimedia terminals.

  2. An automation of design and modelling tasks in NX Siemens environment with original software - generator module

    Science.gov (United States)

    Zbiciak, M.; Grabowik, C.; Janik, W.

    2015-11-01

    Nowadays the design constructional process is almost exclusively aided with CAD/CAE/CAM systems. It is evaluated that nearly 80% of design activities have a routine nature. These design routine tasks are highly susceptible to automation. Design automation is usually made with API tools which allow building original software responsible for adding different engineering activities. In this paper the original software worked out in order to automate engineering tasks at the stage of a product geometrical shape design is presented. The elaborated software works exclusively in NX Siemens CAD/CAM/CAE environment and was prepared in Microsoft Visual Studio with application of the .NET technology and NX SNAP library. The software functionality allows designing and modelling of spur and helicoidal involute gears. Moreover, it is possible to estimate relative manufacturing costs. With the Generator module it is possible to design and model both standard and non-standard gear wheels. The main advantage of the model generated in such a way is its better representation of an involute curve in comparison to those which are drawn in specialized standard CAD systems tools. It comes from fact that usually in CAD systems an involute curve is drawn by 3 points that respond to points located on the addendum circle, the reference diameter of a gear and the base circle respectively. In the Generator module the involute curve is drawn by 11 involute points which are located on and upper the base and the addendum circles therefore 3D gear wheels models are highly accurate. Application of the Generator module makes the modelling process very rapid so that the gear wheel modelling time is reduced to several seconds. During the conducted research the analysis of differences between standard 3 points and 11 points involutes was made. The results and conclusions drawn upon analysis are shown in details.

  3. The Future of Product Design Utilising Printed Electronics

    Science.gov (United States)

    York, Nicola; Southee, Darren; Evans, Mark

    2017-01-01

    This paper addresses the teaching of emerging technologies to design students, using "printed electronics" as an example as it recently became viable to mass manufacture and is ready for use in designs. Printed electronics is introduced as a disruptive technology, and approaches employed in knowledge transfer to industrial/product…

  4. Designing Electronic Performance Support Systems: Models and Instructional Strategies Employed

    Science.gov (United States)

    Nekvinda, Christopher D.

    2011-01-01

    The purpose of this qualitative study was to determine whether instructional designers and performance technologists utilize instructional design models when designing and developing electronic performance support systems (EPSS). The study also explored if these same designers were utilizing instructional strategies within their EPSS to support…

  5. Electronics system design techniques for safety critical applications

    CERN Document Server

    Sterpone, Luca

    2008-01-01

    Addresses the development of techniques for the evaluation and the hardening of designs implemented on SRAM-based Field Programmable Gate Arrays. This title presents a design methodology solving industrial designer''s needs for implementing electronic systems using SRAM-based FPGAs in critical environments, like the space or avionic ones.

  6. User interface design of electronic appliances

    CERN Document Server

    Baumann, Konrad

    2002-01-01

    Foreword by Brenda Laurel. Part One: Introduction 1. Background, Bruce Thomas 2. Introduction, Konrad Baumann 3. The Interaction Design Process, Georg Rakers Part Two: User Interface Design 4. Creativity Techniques, Irene Mavrommati 5. Design Principals, Irene Mavrommati and Adrian Martel 6. Design of On-Screen Interfaces, Irene Mavrommati Part Three: Input Devices 7. Controls, Konrad Baumann 8. Keyboards, Konrad Baumann 9. Advanced Interaction Techniques, Christopher Baber and Konrad Baumann 10. Speech Control, Christopher Baber and Jan Noyes 11. Wearable Computers, Christopher Baber Part Fou

  7. Integrating automated structured analysis and design with Ada programming support environments

    Science.gov (United States)

    Hecht, Alan; Simmons, Andy

    1986-01-01

    Ada Programming Support Environments (APSE) include many powerful tools that address the implementation of Ada code. These tools do not address the entire software development process. Structured analysis is a methodology that addresses the creation of complete and accurate system specifications. Structured design takes a specification and derives a plan to decompose the system subcomponents, and provides heuristics to optimize the software design to minimize errors and maintenance. It can also produce the creation of useable modules. Studies have shown that most software errors result from poor system specifications, and that these errors also become more expensive to fix as the development process continues. Structured analysis and design help to uncover error in the early stages of development. The APSE tools help to insure that the code produced is correct, and aid in finding obscure coding errors. However, they do not have the capability to detect errors in specifications or to detect poor designs. An automated system for structured analysis and design TEAMWORK, which can be integrated with an APSE to support software systems development from specification through implementation is described. These tools completement each other to help developers improve quality and productivity, as well as to reduce development and maintenance costs. Complete system documentation and reusable code also resultss from the use of these tools. Integrating an APSE with automated tools for structured analysis and design provide capabilities and advantages beyond those realized with any of these systems used by themselves.

  8. New Insights into the Composition and Texture of Lunar Regolith Using Ultrafast Automated Electron-Beam Analysis

    Science.gov (United States)

    Rickman, Doug; Wentworth, Susan J.; Schrader, Christian M.; Stoeser, Doug; Botha, Pieter WSK; Butcher, Alan R.; Horsch, Hanna E.; Benedictus, Aukje; Gottlieb, Paul; McKay, David

    2008-01-01

    Sieved grain mounts of Apollo 16 drive tube samples have been examined using QEMSCAN - an innovative electron beam technology. By combining multiple energy-dispersive X-ray detectors, fully automated control, and off-line image processing, to produce digital mineral maps of particles exposed on polished surfaces, the result is an unprecedented quantity of mineralogical and petrographic data, on a particle-by-particle basis. Experimental analysis of four size fractions (500-250 microns, 150-90 microns, 75-45 microns and texture; particle shape, size and density; and the digital classification of distinct particle types in each measured sample. These preliminary data show that there is a decrease in plagioclase modal content and an opposing increase in glass modal content, with decreasing particle size. These findings, together with data on trace phases (metals, sulphides, phosphates, and oxides), provide not only new insights into the make-up of lunar regolith at the Apollo 16 landing site, but also key physical parameters which can be used to design lunar simulants, and compute Figures of Merit for each material produced.

  9. Designing electronic shops, persuading consumers to buy

    DEFF Research Database (Denmark)

    Dormann, Claire

    2000-01-01

    The purpose of this article is to show how to design persuasive and successful Web shops. An approach to commercial site design that draws on theories of visual persuasion is proposed. We focus on the role of emotion. Images in an ad are typically meant to create some emotional disposition toward...

  10. Applying shot boundary detection for automated crystal growth analysis during in situ transmission electron microscope experiments

    Energy Technology Data Exchange (ETDEWEB)

    Moeglein, W. A.; Griswold, R.; Mehdi, B. L.; Browning, N. D.; Teuton, J.

    2017-01-03

    In-situ (scanning) transmission electron microscopy (S/TEM) is being developed for numerous applications in the study of nucleation and growth under electrochemical driving forces. For this type of experiment, one of the key parameters is to identify when nucleation initiates. Typically the process of identifying the moment that crystals begin to form is a manual process requiring the user to perform an observation and respond accordingly (adjust focus, magnification, translate the stage etc.). However, as the speed of the cameras being used to perform these observations increases, the ability of a user to “catch” the important initial stage of nucleation decreases (there is more information that is available in the first few milliseconds of the process). Here we show that video shot boundary detection (SBD) can automatically detect frames where a change in the image occurs. We show that this method can be applied to quickly and accurately identify points of change during crystal growth. This technique allows for automated segmentation of a digital stream for further analysis and the assignment of arbitrary time stamps for the initiation of processes that are independent of the user’s ability to observe and react.

  11. Evaluation of an automated system for root canal irrigation: a scanning electron microscopy study.

    Science.gov (United States)

    Mattioli-Belmonte, Monica; Orsini, Giovanna; Giuliodori, Francesca; DI Cristoforo, Adriano; Procaccini, Maurizio; Mengucci, Paolo; Putignano, Angelo

    2012-01-01

    This study evaluated a new automated system using alternative irrigants for root canal cleaning treatments. This method relies on a system inserting an enzymatic solution based on Trypsin flowing inside the pulp chambers and root canals, completely avoiding traditional endodontic instrumentation. Sixty freshly extracted human molar teeth were randomly divided into 4 groups to assess 3 regimens (R1-3) differing in 0.25% Trypsin/EDTA and 5% Sodium Hypochlorite (NaOCl) solutions administration. Scanning electron microscopy observations and scores taking into account changes in dentin tubules were used to assess treatment effects in pulp chambers and roots. Significant changes in root cleaning ability relative to administration timing were observed, with the best results found in R3, with scheduled alternated cycles of Trypsin/EDTA and NaOCl inside the tooth. The non-invasive root canal method demonstrates good teeth cleaning ability independent of root morphology. This equipment may provide lower discomfort levels for patients undergoing endodontic treatment.

  12. Design and analysis on sorting blade for automated size-based sorting device

    Science.gov (United States)

    Razali, Zol Bahri; Kader, Mohamed Mydin M. Abdul; Samsudin, Yasser Suhaimi; Daud, Mohd Hisam

    2017-09-01

    Nowadays rubbish separating or recycling is a main problem of nation, where peoples dumped their rubbish into dumpsite without caring the value of the rubbish if it can be recycled and reused. Thus the author proposed an automated segregating device, purposely to teach people to separate their rubbish and value the rubbish that can be reused. The automated size-based mechanical segregating device provides significant improvements in terms of efficiency and consistency in this segregating process. This device is designed to make recycling easier, user friendly, in the hope that more people will take responsibility if it is less of an expense of time and effort. This paper discussed about redesign a blade for the sorting device which is to develop an efficient automated mechanical sorting device for the similar material but in different size. The machine is able to identify the size of waste and it depends to the coil inside the container to separate it out. The detail design and methodology is described in detail in this paper.

  13. Overview of software products for the terrain analysis in the tasks of design automation of wind-power stations

    National Research Council Canada - National Science Library

    Volkov, A. A; Sukneva, L. V; Kirschke, H

    2014-01-01

    .... It is necessary to automate the processes of the design technology for the alternative energy structures and their operation, as well as data gathering and analisys on all the existing objects...

  14. HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering

    National Research Council Canada - National Science Library

    Bendl, Jaroslav; Stourac, Jan; Sebestova, Eva; Vavra, Ondrej; Musil, Milos; Brezovsky, Jan; Damborsky, Jiri

    2016-01-01

    HotSpot Wizard 2.0 is a web server for automated identification of hot spots and design of smart libraries for engineering proteins' stability, catalytic activity, substrate specificity and enantioselectivity...

  15. The Design and Implementation of an Automated Security Compliance Toolkit: A Pedagogical Exercise

    Directory of Open Access Journals (Sweden)

    Guillermo Francia III

    2007-12-01

    Full Text Available The demand, through government regulations, for the preservation of the security, integrity, and privacy of corporate and customer information is increasing at an unprecedented pace. Government and private entities struggle to comply with these regulations through various means—both automated and manual controls. This paper presents an automated security compliance toolkit that is designed and developed using mostly open source tools to demonstrate that 1 meeting regulatory compliance does not need to be a very expensive proposition and 2 an undertaking of this magnitude could be served as a pedagogical exercise for students in the areas of collaboration, project management, software engineering, information assurance, and regulatory compliance.

  16. Update on the MEIC electron collider ring design

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Fangei [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Derbenev, Yaroslav S. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Harwood, Leigh [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Hutton, Andrew [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Morozov, Vasiliy [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Pilat, Fulvia [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, Yuhong [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Cai, Y. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Nosochkov, Y. M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Sullivan, Michael [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wang, M.-H [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wienands, Uli [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2015-09-01

    The electron collider ring of the Medium-energy Electron-Ion Collider (MEIC) at Jefferson Lab is designed to accumulate and store a high-current polarized electron beam for collisions with an ion beam. We consider a design of the electron collider ring based on reusing PEP-II components, such as magnets, power supplies, vacuum system, etc. This has the potential to significantly reduce the cost and engineering effort needed to bring the project to fruition. This paper reports on an electron ring optics design considering the balance of PEP-II hardware parameters (such as dipole sagitta, magnet field strengths and acceptable synchrotron radiation power) and electron beam quality in terms of equilibrium emittances.

  17. Power electronic modules design and manufacture

    CERN Document Server

    Sheng, William W

    2004-01-01

    IntroductionSelection ProcedureMaterialsInsulating Substrate and MetallizationBase PlateBonding MaterialPower Interconnection and TerminalEncapsulantPlastic Case and Cover Manufacturing of Power IGBT ModulesManufacturing Process Process Control/Long-Term ReliabilityManufacturing FacilitiesManufacturing Flow Charts DesignThermal ManagementCircuit PartitioningDesign Guidelines and ConsiderationsThermal Results of Different Samples

  18. Methodology and planning for a microprocessor-oriented real time controller design automation system

    Energy Technology Data Exchange (ETDEWEB)

    Matelan, M.N.; Smith, R.J. II

    1976-11-04

    A methodology for reducing the complexity of designing dedicated real-time control systems is developed. It is shown that three areas are amenable to automation: the selection and configuration of hardware, the production of software, and the adaptation of a monitor to maintain real-time integrity of the entire system. The concept of hardware binding is introduced, and it is shown that delaying the point in the design cycle where hardware is functionally bound allows a new approach to machine independence. Concepts which allow expression of repetitive control situations are described, and a realization-independent language (CSDL), based on these concepts, is defined. Methods for automatically selecting a time-wise correct monitor are classified, and techniques for specifying the realization capabilities of digital processors are discussed. These concepts and techniques are brought together in a design automation system for the production of a complete controller design from a behavioral description. An example description is traced through the CSD System; a software listing and hardware configuration document for an actual microprocessor (the Intel 8080) is produced. This research provides a structured description of the control system design process, and allows a unified perspective in the realization of controllers for applications previously considered to be unrelated. The concepts developed define a new direction in the production of real-time control systems. 9 figures, 4 tables.

  19. Power electronics basics operating principles, design, formulas, and applications

    CERN Document Server

    Rozanov, Yuriy; Chaplygin, Evgeny; Voronin, Pavel

    2015-01-01

    Power Electronics Basics: Operating Principles, Design, Formulas, and Applications provides fundamental knowledge for the analysis and design of modern power electronic devices. This concise and user-friendly resource:Explains the basic concepts and most important terms of power electronicsDescribes the power assemblies, control, and passive components of semiconductor power switchesCovers the control of power electronic devices, from mathematical modeling to the analysis of the electrical processesAddresses pulse-width modulation, power quality control, and multilevel, modular, and multicell

  20. Model based design of electronic throttle control

    Science.gov (United States)

    Cherian, Fenin; Ranjan, Ashish; Bhowmick, Pathikrit; Rammohan, A.

    2017-11-01

    With the advent of torque based Engine Management Systems, the precise control and robust performance of the throttle body becomes a key factor in the overall performance of the vehicle. Electronic Throttle Control provides benefits such as improved air-fuel ratio for improving the vehicle performance and lower exhausts emissions to meet the stringent emission norms. Modern vehicles facilitate various features such as Cruise Control, Traction Control, Electronic Stability Program and Pre-crash systems. These systems require control over engine power without driver intervention, which is not possible with conventional mechanical throttle system. Thus these systems are integrated to function with the electronic throttle control. However, due to inherent non-linearities in the throttle body, the control becomes a difficult task. In order to eliminate the influence of this hysteresis at the initial operation of the butterfly valve, a control to compensate the shortage must be added to the duty required for starting throttle operation when the initial operation is detected. Therefore, a lot of work is being done in this field to incorporate the various nonlinearities to achieve robust control. In our present work, the ETB was tested to verify the working of the system. Calibration of the TPS sensors was carried out in order to acquire accurate throttle opening angle. The response of the calibrated system was then plotted against a step input signal. A linear model of the ETB was prepared using Simulink and its response was compared with the experimental data to find out the initial deviation of the model from the actual system. To reduce this deviation, non-linearities from existing literature were introduced to the system and a response analysis was performed to check the deviation from the actual system. Based on this investigation, an introduction of a new nonlinearity parameter can be used in future to reduce the deviation further making the control of the ETB more

  1. Using mathematical software to design power electronic converters

    Science.gov (United States)

    Hinov, Nikolay; Hranov, Tsveti

    2017-12-01

    In the paper is presented mathematical software, which was used for design of power electronic devices. Examined to different example, which are applied to designing electronic converters. In this way, it is possible to play different combinations of the circuit elements by simple means, thus optimizing according to certain criteria and limitations. Free software with a simple and intuitive interface is selected. No special user training is required to work with it and no further training is required. The use of mathematical software greatly facilitates the design, assists and makes it attractive and accessible to a wider range of students and specialists in power electronics training.

  2. Evidence Report, Risk of Inadequate Design of Human and Automation/Robotic Integration

    Science.gov (United States)

    Zumbado, Jennifer Rochlis; Billman, Dorrit; Feary, Mike; Green, Collin

    2011-01-01

    The success of future exploration missions depends, even more than today, on effective integration of humans and technology (automation and robotics). This will not emerge by chance, but by design. Both crew and ground personnel will need to do more demanding tasks in more difficult conditions, amplifying the costs of poor design and the benefits of good design. This report has looked at the importance of good design and the risks from poor design from several perspectives: 1) If the relevant functions needed for a mission are not identified, then designs of technology and its use by humans are unlikely to be effective: critical functions will be missing and irrelevant functions will mislead or drain attention. 2) If functions are not distributed effectively among the (multiple) participating humans and automation/robotic systems, later design choices can do little to repair this: additional unnecessary coordination work may be introduced, workload may be redistributed to create problems, limited human attentional resources may be wasted, and the capabilities of both humans and technology underused. 3) If the design does not promote accurate understanding of the capabilities of the technology, the operators will not use the technology effectively: the system may be switched off in conditions where it would be effective, or used for tasks or in contexts where its effectiveness may be very limited. 4) If an ineffective interaction design is implemented and put into use, a wide range of problems can ensue. Many involve lack of transparency into the system: operators may be unable or find it very difficult to determine a) the current state and changes of state of the automation or robot, b) the current state and changes in state of the system being controlled or acted on, and c) what actions by human or by system had what effects. 5) If the human interfaces for operation and control of robotic agents are not designed to accommodate the unique points of view and

  3. Design-based metrology: advanced automation for CD-SEM recipe generation

    Science.gov (United States)

    Tabery, C.; Capodieci, L.; Haidinyak, C.; Shah, K.; Threefoot, M.; Choo, B.; Singh, B.; Nehmadi, Y.; Ofek, C.; Menadeva, O.; Ben-Porath, A.

    2005-05-01

    The procedure for properly implementing OPC for a new technology node or chip design involves multiple steps: selection of the RET (resolution enhance technique), selection of design rules, OPC Model Building, OPC Verification, CD control quantification (across chip, reticle, wafer, focus, exposure, etc), calibration of Optical Rule Checks (ORC), and other verification steps. Many of these steps require up to thousands of wafer measurements, and while state-of-the-art CD-SEM tools provide automated metrology for production, manually creating a CD recipe with thousands of unique sites is extremely tedious and error-prone. This places a practical limit on both the quality and number of measurements that can be acquired during the technology development and qualification period. At the same time, the number of measurements required to qualify a new reticle design has increased drastically due to the growing complexity of RET and diminishing tolerances. To meet this challenge, a direct and automated link from the design systems to the process metrology tools is needed. Novel methodologies must also be developed to enable automated generation of teh recipe from the design inputs and to translate the flood of metrology results into information that can improve the design, mask data processing, or the patterning process. To facilitate this two-way data flow, a new framework has been created enabling true Design-Based Metrology (DBM), and an application named OPC-Check has been developed to operate within this framework. This DBM framework provides the common language and interface that facilitates the direct transfer of desired measurement locations from teh design to the metrology tool. This link is a critical element in Design for Manufacturability (DFM) efforts, a central theme in many presentations at Microlithography 2005. This article discusses the significant benefits of the tight integration of design and process metrology for OPC implementation in a new

  4. Effects of an Advanced Reactor’s Design, Use of Automation, and Mission on Human Operators

    Energy Technology Data Exchange (ETDEWEB)

    Jeffrey C. Joe; Johanna H. Oxstrand

    2014-06-01

    The roles, functions, and tasks of the human operator in existing light water nuclear power plants (NPPs) are based on sound nuclear and human factors engineering (HFE) principles, are well defined by the plant’s conduct of operations, and have been validated by years of operating experience. However, advanced NPPs whose engineering designs differ from existing light-water reactors (LWRs) will impose changes on the roles, functions, and tasks of the human operators. The plans to increase the use of automation, reduce staffing levels, and add to the mission of these advanced NPPs will also affect the operator’s roles, functions, and tasks. We assert that these factors, which do not appear to have received a lot of attention by the design engineers of advanced NPPs relative to the attention given to conceptual design of these reactors, can have significant risk implications for the operators and overall plant safety if not mitigated appropriately. This paper presents a high-level analysis of a specific advanced NPP and how its engineered design, its plan to use greater levels of automation, and its expanded mission have risk significant implications on operator performance and overall plant safety.

  5. Binding the Electronic Book: Design Features for Bibliophiles

    Science.gov (United States)

    Ruecker, Stan; Uszkalo, Kirsten C.

    2007-01-01

    This paper proposes a design for the electronic book based on discussions with frequent book readers. We adopted a conceptual framework for this project consisting of a spectrum of possible designs, with the conventional bound book at one difference pole, and the laptop computer at the other; the design activity then consisted of appropriately…

  6. Espina: A Tool for the Automated Segmentation and Counting of Synapses in Large Stacks of Electron Microscopy Images

    Science.gov (United States)

    Morales, Juan; Alonso-Nanclares, Lidia; Rodríguez, José-Rodrigo; DeFelipe, Javier; Rodríguez, Ángel; Merchán-Pérez, Ángel

    2011-01-01

    The synapses in the cerebral cortex can be classified into two main types, Gray's type I and type II, which correspond to asymmetric (mostly glutamatergic excitatory) and symmetric (inhibitory GABAergic) synapses, respectively. Hence, the quantification and identification of their different types and the proportions in which they are found, is extraordinarily important in terms of brain function. The ideal approach to calculate the number of synapses per unit volume is to analyze 3D samples reconstructed from serial sections. However, obtaining serial sections by transmission electron microscopy is an extremely time consuming and technically demanding task. Using focused ion beam/scanning electron microscope microscopy, we recently showed that virtually all synapses can be accurately identified as asymmetric or symmetric synapses when they are visualized, reconstructed, and quantified from large 3D tissue samples obtained in an automated manner. Nevertheless, the analysis, segmentation, and quantification of synapses is still a labor intensive procedure. Thus, novel solutions are currently necessary to deal with the large volume of data that is being generated by automated 3D electron microscopy. Accordingly, we have developed ESPINA, a software tool that performs the automated segmentation and counting of synapses in a reconstructed 3D volume of the cerebral cortex, and that greatly facilitates and accelerates these processes. PMID:21633491

  7. Automated Generation of Finite-Element Meshes for Aircraft Conceptual Design

    Science.gov (United States)

    Li, Wu; Robinson, Jay

    2016-01-01

    This paper presents a novel approach for automated generation of fully connected finite-element meshes for all internal structural components and skins of a given wing-body geometry model, controlled by a few conceptual-level structural layout parameters. Internal structural components include spars, ribs, frames, and bulkheads. Structural layout parameters include spar/rib locations in wing chordwise/spanwise direction and frame/bulkhead locations in longitudinal direction. A simple shell thickness optimization problem with two load conditions is used to verify versatility and robustness of the automated meshing process. The automation process is implemented in ModelCenter starting from an OpenVSP geometry and ending with a NASTRAN 200 solution. One subsonic configuration and one supersonic configuration are used for numerical verification. Two different structural layouts are constructed for each configuration and five finite-element meshes of different sizes are generated for each layout. The paper includes various comparisons of solutions of 20 thickness optimization problems, as well as discussions on how the optimal solutions are affected by the stress constraint bound and the initial guess of design variables.

  8. ECO fill: automated fill modification to support late-stage design changes

    Science.gov (United States)

    Davis, Greg; Wilson, Jeff; Yu, J. J.; Chiu, Anderson; Chuang, Yao-Jen; Yang, Ricky

    2014-03-01

    One of the most critical factors in achieving a positive return for a design is ensuring the design not only meets performance specifications, but also produces sufficient yield to meet the market demand. The goal of design for manufacturability (DFM) technology is to enable designers to address manufacturing requirements during the design process. While new cell-based, DP-aware, and net-aware fill technologies have emerged to provide the designer with automated fill engines that support these new fill requirements, design changes that arrive late in the tapeout process (as engineering change orders, or ECOs) can have a disproportionate effect on tapeout schedules, due to the complexity of replacing fill. If not handled effectively, the impacts on file size, run time, and timing closure can significantly extend the tapeout process. In this paper, the authors examine changes to design flow methodology, supported by new fill technology, that enable efficient, fast, and accurate adjustments to metal fill late in the design process. We present an ECO fill methodology coupled with the support of advanced fill tools that can quickly locate the portion of the design affected by the change, remove and replace only the fill in that area, while maintaining the fill hierarchy. This new fill approach effectively reduces run time, contains fill file size, minimizes timing impact, and minimizes mask costs due to ECO-driven fill changes, all of which are critical factors to ensuring time-to-market schedules are maintained.

  9. Electronic Modeling and Design for Extreme Temperatures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We are developing CAD tools, models and methodologies for electronics design for circuit operation in extreme environments with focus on very low temperatures...

  10. Designing a curriculum about electron microscope based on ...

    African Journals Online (AJOL)

    Ten books from reference books and electronic sources were selected as samples for design the syllabus. The objectives and content was developed according to disciplinary method. Finally, researchers propose 4 objectives and 10 contents about electron microscope learning for undergraduates. The main objects are: ...

  11. Automated Program Design – an Example Solving a Weather Forecasting Problem

    Directory of Open Access Journals (Sweden)

    Doroshenko Anatoliy

    2016-01-01

    Full Text Available High-level algebra-algorithmic software tools for automated design of parallel code in the OpenMP environment are developed for the purpose of both producing efficient parallel code and increasing the performance of program developers. Application of the tools is illustrated with an example of a problem in atmosphere circulation modeling, represented as a service belonging to an Internet portal providing meteorological forecasting services. Results of execution of the parallel weather forecasting program on multiprocessor platforms are given.

  12. An evaluation of two automated quality control methods designed for use with hourly wind profiler data

    Directory of Open Access Journals (Sweden)

    P. A. Miller

    1994-07-01

    Full Text Available The National Oceanic and Atmospheric Administration (NOAA has completed the installation of a 30-site demonstration network of wind-profiling radars in the central United States. The network is being used to demonstrate and assess the utility of wind profiler technology in a quasi-operational environment, and to help define operational requirements for possible future national networks. This paper describes two automated quality control methods designed to remove erroneous winds from the hourly network data. Case study examples and statistical evaluation of the performance of each method are also presented.

  13. Vectorial electron transfer on designed surfaces

    Science.gov (United States)

    Bard, A. J.; Campion, A.; Fox, M. A.; Mallouk, T. E.; Webber, S. E.

    Bipolar CdSe/CoS semiconductor photoelectrode panels, capable of vectorial electron transfer, were used in series arrays to photodecompose water to yield hydrogen and oxygen in stoichiometric ratio with a maximum solar efficiency of about 1 precent. An analytical model was developed for these arrays which addresses the question of watersplitting and electrical power generation efficiencies as functions of the number of panels, the overpotential of the gas generating electrodes, incident light intensity, and the concentrations of the redox couples. Hydrogen production using a self-assembling zeolite system was discovered. Sensitized anatase TiO2 electrodes were used in photoelectrochemical cells employing variety of solution redox couples. The photoassisted production of hydrogen from methanol-water solutions containing mixtures of small particles of CdS/SiO2 and a wide bandgap semiconductor (TiO, ZnO, SnO2, or WO3), supported on silica and platinized was studied. The phenomenon of interparticle charge separation for Cds/SiO2 was found to be operative for CdS/SiO2 with WS sub 2/SiO2.

  14. Automated inter-rater reliability assessment and electronic data collection in a multi-center breast cancer study

    Directory of Open Access Journals (Sweden)

    Enger Shelley M

    2007-06-01

    Full Text Available Abstract Background The choice between paper data collection methods and electronic data collection (EDC methods has become a key question for clinical researchers. There remains a need to examine potential benefits, efficiencies, and innovations associated with an EDC system in a multi-center medical record review study. Methods A computer-based automated menu-driven system with 658 data fields was developed for a cohort study of women aged 65 years or older, diagnosed with invasive histologically confirmed primary breast cancer (N = 1859, at 6 Cancer Research Network sites. Medical record review with direct data entry into the EDC system was implemented. An inter-rater and intra-rater reliability (IRR system was developed using a modified version of the EDC. Results Automation of EDC accelerated the flow of study information and resulted in an efficient data collection process. Data collection time was reduced by approximately four months compared to the project schedule and funded time available for manuscript preparation increased by 12 months. In addition, an innovative modified version of the EDC permitted an automated evaluation of inter-rater and intra-rater reliability across six data collection sites. Conclusion Automated EDC is a powerful tool for research efficiency and innovation, especially when multiple data collection sites are involved.

  15. Automated design and optimization of flexible booster autopilots via linear programming, volume 1

    Science.gov (United States)

    Hauser, F. D.

    1972-01-01

    A nonlinear programming technique was developed for the automated design and optimization of autopilots for large flexible launch vehicles. This technique, which resulted in the COEBRA program, uses the iterative application of linear programming. The method deals directly with the three main requirements of booster autopilot design: to provide (1) good response to guidance commands; (2) response to external disturbances (e.g. wind) to minimize structural bending moment loads and trajectory dispersions; and (3) stability with specified tolerances on the vehicle and flight control system parameters. The method is applicable to very high order systems (30th and greater per flight condition). Examples are provided that demonstrate the successful application of the employed algorithm to the design of autopilots for both single and multiple flight conditions.

  16. FireProt: web server for automated design of thermostable proteins

    Science.gov (United States)

    Musil, Milos; Stourac, Jan; Brezovsky, Jan; Prokop, Zbynek; Zendulka, Jaroslav; Martinek, Tomas

    2017-01-01

    Abstract There is a continuous interest in increasing proteins stability to enhance their usability in numerous biomedical and biotechnological applications. A number of in silico tools for the prediction of the effect of mutations on protein stability have been developed recently. However, only single-point mutations with a small effect on protein stability are typically predicted with the existing tools and have to be followed by laborious protein expression, purification, and characterization. Here, we present FireProt, a web server for the automated design of multiple-point thermostable mutant proteins that combines structural and evolutionary information in its calculation core. FireProt utilizes sixteen tools and three protein engineering strategies for making reliable protein designs. The server is complemented with interactive, easy-to-use interface that allows users to directly analyze and optionally modify designed thermostable mutants. FireProt is freely available at http://loschmidt.chemi.muni.cz/fireprot. PMID:28449074

  17. User interface design principles for the SSM/PMAD automated power system

    Science.gov (United States)

    Jakstas, Laura M.; Myers, Chris J.

    1991-01-01

    Martin Marietta has developed a user interface for the space station module power management and distribution (SSM/PMAD) automated power system testbed which provides human access to the functionality of the power system, as well as exemplifying current techniques in user interface design. The testbed user interface was designed to enable an engineer to operate the system easily without having significant knowledge of computer systems, as well as provide an environment in which the engineer can monitor and interact with the SSM/PMAD system hardware. The design of the interface supports a global view of the most important data from the various hardware and software components, as well as enabling the user to obtain additional or more detailed data when needed. The components and representations of the SSM/PMAD testbed user interface are examined. An engineer's interactions with the system are also described.

  18. Thermal Design of Power Electronic Circuits

    CERN Document Server

    Künzi, R.

    2015-06-15

    The heart of every switched mode converter consists of several switching semiconductor elements. Due to their non-ideal behaviour there are ON state and switching losses heating up the silicon chip. That heat must effectively be transferred to the environment in order to prevent overheating or even destruction of the element. For a cost-effective design, the semiconductors should be operated close to their thermal limits. Unfortunately the chip temperature cannot be measured directly. Therefore a detailed understanding of how losses arise, including their quantitative estimation, is required. Furthermore, the heat paths to the environment must be understood in detail. This paper describes the main issues of loss generation and its transfer to the environment and how it can be estimated by the help of datasheets and/or experiments.

  19. An Automated BIM Model to Conceptually Design, Analyze, Simulate, and Assess Sustainable Building Projects

    Directory of Open Access Journals (Sweden)

    Farzad Jalaei

    2014-01-01

    Full Text Available Quantifying the environmental impacts and simulating the energy consumption of building’s components at the conceptual design stage are very helpful for designers needing to make decisions related to the selection of the best design alternative that would lead to a more energy efficient building. Building Information Modeling (BIM offers designers the ability to assess different design alternatives at the conceptual stage of the project so that energy and life cycle assessment (LCA strategies and systems are attained. This paper proposes an automated model that links BIM, LCA, energy analysis, and lighting simulation tools with green building certification systems. The implementation is within developing plug-ins on BIM tool capable of measuring the environmental impacts (EI and embodied energy of building components. Using this method, designers will be provided with a new way to visualize and to identify the potential gain or loss of energy for the building as a whole and for each of its associated components. Furthermore, designers will be able to detect and evaluate the sustainability of the proposed buildings based on Leadership in Energy and Environmental Design (LEED rating system. An actual building project will be used to illustrate the workability of the proposed methodology.

  20. APPROACH TO AUTOMATION OF LENS COMPONENTS CENTERING FOR ASSEMBLING OF DIFFERENT DESIGN OBJECTIVES

    Directory of Open Access Journals (Sweden)

    A. Y. Pimenov

    2016-01-01

    Full Text Available Subject of Research.Existing adjustment methods of lens objectives in two mechanical designs have been analyzed, the main ways of centering error compensation have been considered. The algorithm of automated search of optical elements position has been developed based on the existing methods of centering for compensation of residual decentering. The methods of joint application of this algorithm and centering machine “Trioptics Opticentric” have been suggested. Method. Centering errors of the objective lens components are measured on the centering machine. Aberrations of optical system are calculated by using the received data of centering errors entered to the objective mathematical model. For the calculation of aberration compensation, iteration algorithm of searching of optical elements optimal position is used. The image quality is analyzed for each obtained realization of the optical system. The result of program performance is data matrix about optical components location such that compensation of residual aberrations occurs. Based on the obtained information the system assembling is carried out with the use of centering machine “Trioptics Opticentric”. Main Results. Computer modeling of centering errors for 100 lens apochromatic objectives of drop-in mountings lens design has been carried out. The coma of object axial point image has been chosen as quality estimation criterion. The developed algorithm has been applied for the worst realization of the optical system. In this case the value of integral coma of object axial point image has been decreased by two orders and reduced practically to zero. It is noted that the modeling of adjustment process via using the algorithm of automated search enables to predict the possibility of objective assembly with required quality parameters. Practical Relevance. The received results can be applied on the lines of automated assembly of modern lens objectives.

  1. ESPINA: a tool for the automated segmentation and counting of synapses in large stacks of electron microscopy images

    Directory of Open Access Journals (Sweden)

    Juan eMorales

    2011-03-01

    Full Text Available The synapses in the cerebral cortex can be classified into two main types, Gray’s type I and type II, which correspond to asymmetric (mostly glutamatergic excitatory and symmetric (inhibitory GABAergic synapses, respectively. Hence, the quantification and identification of their different types and the proportions in which they are found, is extraordinarily important in terms of brain function. The ideal approach to calculate the number of synapses per unit volume is to analyze three-dimensional samples reconstructed from serial sections. However, obtaining serial sections by transmission electron microscopy is an extremely time consuming and technically demanding task. Using FIB/SEM microscopy, we recently showed that virtually all synapses can be accurately identified as asymmetric or symmetric synapses when they are visualized, reconstructed and quantified from large three-dimensional tissue samples obtained in an automated manner. Nevertheless, the analysis, segmentation and quantification of synapses is still a labor intensive procedure. Thus, novel solutions are currently necessary to deal with the large volume of data that is being generated by automated 3D electron microscopy. Accordingly, we have developed ESPINA, a software tool that performs the automated segmentation and counting of synapses in a reconstructed 3D volume of the cerebral cortex, and that greatly facilitates and accelerates these processes.

  2. Automated solar collector installation design including ability to define heterogeneous design preferences

    Science.gov (United States)

    Wayne, Gary; Frumkin, Alexander; Zaydman, Michael; Lehman, Scott; Brenner, Jules

    2013-01-08

    Embodiments may include systems and methods to create and edit a representation of a worksite, to create various data objects, to classify such objects as various types of pre-defined "features" with attendant properties and layout constraints. As part of or in addition to classification, an embodiment may include systems and methods to create, associate, and edit intrinsic and extrinsic properties to these objects. A design engine may apply of design rules to the features described above to generate one or more solar collectors installation design alternatives, including generation of on-screen and/or paper representations of the physical layout or arrangement of the one or more design alternatives. Embodiments may also include definition of one or more design apertures, each of which may correspond to boundaries in which solar collector layouts should comply with distinct sets of user-defined design preferences. Distinct apertures may provide heterogeneous regions of collector layout according to the user-defined design preferences.

  3. E-learning platform for automated testing of electronic circuits using signature analysis method

    Science.gov (United States)

    Gherghina, Cǎtǎlina; Bacivarov, Angelica; Bacivarov, Ioan C.; Petricǎ, Gabriel

    2016-12-01

    Dependability of electronic circuits can be ensured only through testing of circuit modules. This is done by generating test vectors and their application to the circuit. Testability should be viewed as a concerted effort to ensure maximum efficiency throughout the product life cycle, from conception and design stage, through production to repairs during products operating. In this paper, is presented the platform developed by authors for training for testability in electronics, in general and in using signature analysis method, in particular. The platform allows highlighting the two approaches in the field namely analog and digital signature of circuits. As a part of this e-learning platform, it has been developed a database for signatures of different electronic components meant to put into the spotlight different techniques implying fault detection, and from this there were also self-repairing techniques of the systems with this kind of components. An approach for realizing self-testing circuits based on MATLAB environment and using signature analysis method is proposed. This paper analyses the benefits of signature analysis method and simulates signature analyzer performance based on the use of pseudo-random sequences, too.

  4. DATA TRANSFER IN THE AUTOMATED SYSTEM OF PARALLEL DESIGN AND CONSTRUCTION

    Directory of Open Access Journals (Sweden)

    Volkov Andrey Anatol'evich

    2012-12-01

    Full Text Available This article covers data transfer processes in the automated system of parallel design and construction. The authors consider the structure of reports used by contractors and clients when large-scale projects are implemented. All necessary items of information are grouped into three levels, and each level is described by certain attributes. The authors drive a lot of attention to the integrated operational schedule as it is the main tool of project management. Some recommendations concerning the forms and the content of reports are presented. Integrated automation of all operations is a necessary condition for the successful implementation of the new concept. The technical aspect of the notion of parallel design and construction also includes the client-to-server infrastructure that brings together all process implemented by the parties involved into projects. This approach should be taken into consideration in the course of review of existing codes and standards to eliminate any inconsistency between the construction legislation and the practical experience of engineers involved into the process.

  5. Conceptual Design and Feasibility Analyses of a Robotic System for Automated Exterior Wall Painting

    Directory of Open Access Journals (Sweden)

    Young S. Kim

    2008-11-01

    Full Text Available There are approximately 6,677,000 apartment housing units in South Korea. Exterior wall painting for such multi-dwelling apartment housings in South Korea represents a typical area to which construction automation technology can be applied for improvement in safety, productivity, quality, and cost over the conventional method. The conventional exterior wall painting is costly and labor-intensive, and it especially exposes workers to significant health and safety risks. The primary objective of this study is to design a conceptual model of an exterior wall painting robot which is applicable to apartment housing construction and maintenance, and to conduct its technical?economical feasibility analyses. In this study, a design concept using a high ladder truck is proposed as the best alternative for automation of the exterior wall painting. Conclusions made in this study show that the proposed exterior wall painting robot is technically and economically feasible, and can greatly enhance safety, productivity, and quality compared to the conventional method. Finally, it is expected that the conceptual model of the exterior wall painting robot would be efficiently used in various applications in exterior wall finishing and maintenance of other architectural and civil structures such as commercial buildings, towers, and high-rise storage tanks.

  6. Human-Automation Interaction Design for Adaptive Cruise Control Systems of Ground Vehicles.

    Science.gov (United States)

    Eom, Hwisoo; Lee, Sang Hun

    2015-06-12

    A majority of recently developed advanced vehicles have been equipped with various automated driver assistance systems, such as adaptive cruise control (ACC) and lane keeping assistance systems. ACC systems have several operational modes, and drivers can be unaware of the mode in which they are operating. Because mode confusion is a significant human error factor that contributes to traffic accidents, it is necessary to develop user interfaces for ACC systems that can reduce mode confusion. To meet this requirement, this paper presents a new human-automation interaction design methodology in which the compatibility of the machine and interface models is determined using the proposed criteria, and if the models are incompatible, one or both of the models is/are modified to make them compatible. To investigate the effectiveness of our methodology, we designed two new interfaces by separately modifying the machine model and the interface model and then performed driver-in-the-loop experiments. The results showed that modifying the machine model provides a more compact, acceptable, effective, and safe interface than modifying the interface model.

  7. SYNBADm: a tool for optimization-based automated design of synthetic gene circuits.

    Science.gov (United States)

    Otero-Muras, Irene; Henriques, David; Banga, Julio R

    2016-11-01

    The design of de novo circuits with predefined performance specifications is a challenging problem in Synthetic Biology. Computational models and tools have proved to be crucial for a successful wet lab implementation. Natural gene circuits are complex, subject to evolutionary tradeoffs and playing multiple roles. However, most synthetic designs implemented to date are simple and perform a single task. As the field progresses, advanced computational tools are needed in order to handle greater levels of circuit complexity in a more flexible way and considering multiple design criteria. This works presents SYNBADm (SYNthetic Biology Automated optimal Design in Matlab), a software toolbox for the automatic optimal design of gene circuits with targeted functions from libraries of components. This tool makes use of global optimization to simultaneously search the space of structures and kinetic parameters. SYNBADm can efficiently handle high levels of circuit complexity and can consider multiple design criteria through multiobjective optimization. Further, it provides flexible design capabilities, i.e. the user can define the modeling framework, library of components and target performance function(s). SYNBADm runs under the popular MATLAB computational environment, and is available under GPLv3 license at https://sites.google.com/site/synbadm CONTACT: ireneotero@iim.csic.es or julio@iim.csic.es. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  8. Networking automation of ECI’s G-204 electronic engineering laboratory

    Directory of Open Access Journals (Sweden)

    Hernán Paz Penagos

    2010-04-01

    Full Text Available Increased use (by students and teachers of the “Escuela Colombiana de Ingeniería Julio Garavito” Electronic Engineering laboratories during the last year has congested access to these laboratories; the School’s Electronic Engineering (Ecitronica programme’s applied Electronic studies’ centre research group thus proposed, designed and developed a research prolect taking advantage of G building’s electrical distribution to offer access facilities, laboratory equipment control, energy saving and improved service quality. The G-204 laboratory’s network sys- tem will have an access control subsystem with client–main computer architecture. The latter consists of a user, schedule, group and work-bank database; the user is connected from any computer (client to the main computer through Internet to reserve his/her turn at laboratory practice by selecting the schedule, group, work-bank, network type required (1Ф or 3Ф and registering co-workers. Access to the G-204 laboratory on the day and time of practice is made by means of an intelligent card reader. Information of public interest produced and controlled by the main computer is displayed on three LCD screens located on one of G building’s second floor walls, as is an electronic clock. The G-204 laboratory temperature and time are continually updated. Work-banks are enabled or disabled by the main computer; the work banks are provided with power (beginning of practice or disconnected (end of practice or due to eventualities to protect the equipment, save energy, facilitate monitors and supervise the logistics of the state of the equipment at the end of each practice. The research group was organised into Transmission Line and Applications sub-groups. Power Line Communications PLC technology was used for to exploring digital modulation alternatives, coding and detecting errors, coupling, data transmission protocols and new applications, all based on channel estimation (networking

  9. Design for Reliability of Power Electronics in Renewable Energy Systems

    DEFF Research Database (Denmark)

    Ma, Ke; Yang, Yongheng; Wang, Huai

    2014-01-01

    Power electronics is the enabling technology for maximizing the power captured from renewable electrical generation, e.g., the wind and solar technology, and also for an efficient integration into the grid. Therefore, it is important that the power electronics are reliable and do not have too many...... failures during operation which otherwise will increase cost for operation, maintenance and reputation. Typically, power electronics in renewable electrical generation has to be designed for 20–30 years of operation, and in order to do that, it is crucial to know about the mission profile of the power...... electronics technology as well as to know how the power electronics technology is loaded in terms of temperature and other stressors relevant, to reliability. Hence, this chapter will show the basics of power electronics technology for renewable energy systems, describe the mission profile of the technology...

  10. (abstract) Designing for Small Volume Assembly of Advanced Electronics Packages

    Science.gov (United States)

    Galbraith, L.; Bonner, K.

    1995-01-01

    There is a need for high reliability surface mount assembly processes for aerospace, military, and medical applications. This approach for improving design for producibility and reliability of electronic system assembly processes can be utilized as a starting framework. Described herein is a general methodology to Design for Producibility and Reliability (DFPAR) for very small volume production runs.

  11. Rapid prototyping of an automated video surveillance system: a hardware-software co-design approach

    Science.gov (United States)

    Ngo, Hau T.; Rakvic, Ryan N.; Broussard, Randy P.; Ives, Robert W.

    2011-06-01

    FPGA devices with embedded DSP and memory blocks, and high-speed interfaces are ideal for real-time video processing applications. In this work, a hardware-software co-design approach is proposed to effectively utilize FPGA features for a prototype of an automated video surveillance system. Time-critical steps of the video surveillance algorithm are designed and implemented in the FPGAs logic elements to maximize parallel processing. Other non timecritical tasks are achieved by executing a high level language program on an embedded Nios-II processor. Pre-tested and verified video and interface functions from a standard video framework are utilized to significantly reduce development and verification time. Custom and parallel processing modules are integrated into the video processing chain by Altera's Avalon Streaming video protocol. Other data control interfaces are achieved by connecting hardware controllers to a Nios-II processor using Altera's Avalon Memory Mapped protocol.

  12. Automated Pressure Injury Risk Assessment System Incorporated Into an Electronic Health Record System.

    Science.gov (United States)

    Jin, Yinji; Jin, Taixian; Lee, Sun-Mi

    Pressure injury risk assessment is the first step toward preventing pressure injuries, but traditional assessment tools are time-consuming, resulting in work overload and fatigue for nurses. The objectives of the study were to build an automated pressure injury risk assessment system (Auto-PIRAS) that can assess pressure injury risk using data, without requiring nurses to collect or input additional data, and to evaluate the validity of this assessment tool. A retrospective case-control study and a system development study were conducted in a 1,355-bed university hospital in Seoul, South Korea. A total of 1,305 pressure injury patients and 5,220 nonpressure injury patients participated for the development of a risk scoring algorithm: 687 and 2,748 for the validation of the algorithm and 237 and 994 for validation after clinical implementation, respectively. A total of 4,211 pressure injury-related clinical variables were extracted from the electronic health record (EHR) systems to develop a risk scoring algorithm, which was validated and incorporated into the EHR. That program was further evaluated for predictive and concurrent validity. Auto-PIRAS, incorporated into the EHR system, assigned a risk assessment score of high, moderate, or low and displayed this on the Kardex nursing record screen. Risk scores were updated nightly according to 10 predetermined risk factors. The predictive validity measures of the algorithm validation stage were as follows: sensitivity = .87, specificity = .90, positive predictive value = .68, negative predictive value = .97, Youden index = .77, and the area under the receiver operating characteristic curve = .95. The predictive validity measures of the Braden Scale were as follows: sensitivity = .77, specificity = .93, positive predictive value = .72, negative predictive value = .95, Youden index = .70, and the area under the receiver operating characteristic curve = .85. The kappa of the Auto-PIRAS and Braden Scale risk

  13. Design for low-power and reliable flexible electronics

    Science.gov (United States)

    Huang, Tsung-Ching (Jim)

    Flexible electronics are emerging as an alternative to conventional Si electronics for large-area low-cost applications such as e-paper, smart sensors, and disposable RFID tags. By utilizing inexpensive manufacturing methods such as ink-jet printing and roll-to-roll imprinting, flexible electronics can be made on low-cost plastics just like printing a newspaper. However, the key elements of exible electronics, thin-film transistors (TFTs), have slower operating speeds and less reliability than their Si electronics counterparts. Furthermore, depending on the material property, TFTs are usually mono-type -- either p- or n-type -- devices. Making air-stable complementary TFT circuits is very challenging and not applicable to most TFT technologies. Existing design methodologies for Si electronics, therefore, cannot be directly applied to exible electronics. Other inhibiting factors such as high supply voltage, large process variation, and lack of trustworthy device modeling also make designing larger-scale and robust TFT circuits a significant challenge. The major goal of this dissertation is to provide a viable solution for robust circuit design in exible electronics. I will first introduce a reliability simulation framework that can predict the degraded TFT circuits' performance under bias-stress. This framework has been validated using the amorphous-silicon (a-Si) TFT scan driver for TFT-LCD displays. To reuse the existing CMOS design ow for exible electronics, I propose a Pseudo-CMOS cell library that can make TFT circuits operable under low supply voltage and which has post-fabrication tunability for reliability and performance enhancement. This cell library has been validated using 2V self-assembly-monolayer (SAM) organic TFTs with a low-cost shadow-mask deposition process. I will also demonstrate a 3-bit 1.25KS/s Flash ADC in a-Si TFTs, which is based on the proposed Pseudo-CMOS cell library, and explore more possibilities in display, energy, and sensing

  14. Methodology, Algorithms, and Emerging Tool for Automated Design of Intelligent Integrated Multi-Sensor Systems

    Directory of Open Access Journals (Sweden)

    Andreas König

    2009-11-01

    Full Text Available The emergence of novel sensing elements, computing nodes, wireless communication and integration technology provides unprecedented possibilities for the design and application of intelligent systems. Each new application system must be designed from scratch, employing sophisticated methods ranging from conventional signal processing to computational intelligence. Currently, a significant part of this overall algorithmic chain of the computational system model still has to be assembled manually by experienced designers in a time and labor consuming process. In this research work, this challenge is picked up and a methodology and algorithms for automated design of intelligent integrated and resource-aware multi-sensor systems employing multi-objective evolutionary computation are introduced. The proposed methodology tackles the challenge of rapid-prototyping of such systems under realization constraints and, additionally, includes features of system instance specific self-correction for sustained operation of a large volume and in a dynamically changing environment. The extension of these concepts to the reconfigurable hardware platform renders so called self-x sensor systems, which stands, e.g., for self-monitoring, -calibrating, -trimming, and -repairing/-healing systems. Selected experimental results prove the applicability and effectiveness of our proposed methodology and emerging tool. By our approach, competitive results were achieved with regard to classification accuracy, flexibility, and design speed under additional design constraints.

  15. Robotized semiautomatic motorcycle transmission development. Electronic and software design

    OpenAIRE

    Neghină Mihai; Petruse Radu Emanuil; Olteanu Sebastian; Bondrea Ioan; Lobonț Lucian; Stanciu Gabriel

    2017-01-01

    In this paper, we propose an electrical design (implemented on a PCB board) and an accompanying software design for controlling the automatic gear change. The designs complement the mechanical solutions developed in Part 1. The paper also analyses the issues encountered during the intermediate steps of the development of the electronic module, which is expected to be small and adaptable enough to be installed on a motorcycle without changing its ergonomics. The control software runs on the Ar...

  16. Automated sub-5 nm image registration in integrated correlative fluorescence and electron microscopy using cathodoluminescence pointers

    Science.gov (United States)

    Haring, Martijn T.; Liv, Nalan; Zonnevylle, A. Christiaan; Narvaez, Angela C.; Voortman, Lenard M.; Kruit, Pieter; Hoogenboom, Jacob P.

    2017-03-01

    In the biological sciences, data from fluorescence and electron microscopy is correlated to allow fluorescence biomolecule identification within the cellular ultrastructure and/or ultrastructural analysis following live-cell imaging. High-accuracy (sub-100 nm) image overlay requires the addition of fiducial markers, which makes overlay accuracy dependent on the number of fiducials present in the region of interest. Here, we report an automated method for light-electron image overlay at high accuracy, i.e. below 5 nm. Our method relies on direct visualization of the electron beam position in the fluorescence detection channel using cathodoluminescence pointers. We show that image overlay using cathodoluminescence pointers corrects for image distortions, is independent of user interpretation, and does not require fiducials, allowing image correlation with molecular precision anywhere on a sample.

  17. Vibration-based Energy Harvesting Systems Characterization Using Automated Electronic Equipment

    Directory of Open Access Journals (Sweden)

    Ioannis KOSMADAKIS

    2015-04-01

    Full Text Available A measurement bench has been developed to fully automate the procedure for the characterization of a vibration-based energy scavenging system. The measurement system is capable of monitoring all important characteristics of a vibration harvesting system (input and output voltage, current, and other parameters, frequency and acceleration values, etc.. It is composed of a PC, typical digital measuring instruments (oscilloscope, waveform generator, etc., certain sensors and actuators, along with a microcontroller based automation module. The automation of the procedure and the manipulation of the acquired data are performed by LabVIEW software. Typical measurements of a system consisting of a vibrating source, a vibration transducer and an active rectifier are presented.

  18. A Reliability-Oriented Design Method for Power Electronic Converters

    DEFF Research Database (Denmark)

    Wang, Huai; Zhou, Dao; Blaabjerg, Frede

    2013-01-01

    Reliability is a crucial performance indicator of power electronic systems in terms of availability, mission accomplishment and life cycle cost. A paradigm shift in the research on reliability of power electronics is going on from simple handbook based calculations (e.g. models in MIL-HDBK-217F h...... and reliability prediction models are provided. A case study on a 2.3 MW wind power converter is discussed with emphasis on the reliability critical component IGBT modules.......Reliability is a crucial performance indicator of power electronic systems in terms of availability, mission accomplishment and life cycle cost. A paradigm shift in the research on reliability of power electronics is going on from simple handbook based calculations (e.g. models in MIL-HDBK-217F...... handbook) to the physics-of-failure approach and design for reliability process. A systematic design procedure consisting of various design tools is presented in this paper to design reliability into the power electronic converters since the early concept phase. The corresponding design procedures...

  19. Application of the H-Mode, a Design and Interaction Concept for Highly Automated Vehicles, to Aircraft

    Science.gov (United States)

    Goodrich, Kenneth H.; Flemisch, Frank O.; Schutte, Paul C.; Williams, Ralph A.

    2006-01-01

    Driven by increased safety, efficiency, and airspace capacity, automation is playing an increasing role in aircraft operations. As aircraft become increasingly able to autonomously respond to a range of situations with performance surpassing human operators, we are compelled to look for new methods that help us understand their use and guide their design using new forms of automation and interaction. We propose a novel design metaphor to aid the conceptualization, design, and operation of highly-automated aircraft. Design metaphors transfer meaning from common experiences to less familiar applications or functions. A notable example is the "Desktop metaphor" for manipulating files on a computer. This paper describes a metaphor for highly automated vehicles known as the H-metaphor and a specific embodiment of the metaphor known as the H-mode as applied to aircraft. The fundamentals of the H-metaphor are reviewed followed by an overview of an exploratory usability study investigating human-automation interaction issues for a simple H-mode implementation. The envisioned application of the H-mode concept to aircraft is then described as are two planned evaluations.

  20. Derivation and validation of the automated search algorithms to identify cognitive impairment and dementia in electronic health records.

    Science.gov (United States)

    Amra, Sakusic; O'Horo, John C; Singh, Tarun D; Wilson, Gregory A; Kashyap, Rahul; Petersen, Ronald; Roberts, Rosebud O; Fryer, John D; Rabinstein, Alejandro A; Gajic, Ognjen

    2017-02-01

    Long-term cognitive impairment is a common and important problem in survivors of critical illness. We developed electronic search algorithms to identify cognitive impairment and dementia from the electronic medical records (EMRs) that provide opportunity for big data analysis. Eligible patients met 2 criteria. First, they had a formal cognitive evaluation by The Mayo Clinic Study of Aging. Second, they were hospitalized in intensive care unit at our institution between 2006 and 2014. The "criterion standard" for diagnosis was formal cognitive evaluation supplemented by input from an expert neurologist. Using all available EMR data, we developed and improved our algorithms in the derivation cohort and validated them in the independent validation cohort. Of 993 participants who underwent formal cognitive testing and were hospitalized in intensive care unit, we selected 151 participants at random to form the derivation and validation cohorts. The automated electronic search algorithm for cognitive impairment was 94.3% sensitive and 93.0% specific. The search algorithms for dementia achieved respective sensitivity and specificity of 97% and 99%. EMR search algorithms significantly outperformed International Classification of Diseases codes. Automated EMR data extractions for cognitive impairment and dementia are reliable and accurate and can serve as acceptable and efficient alternatives to time-consuming manual data review. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Design and implementation of an automated compound management system in support of lead optimization.

    Science.gov (United States)

    Quintero, Catherine; Kariv, Ilona

    2009-06-01

    To meet the needs of the increasingly rapid and parallelized lead optimization process, a fully integrated local compound storage and liquid handling system was designed and implemented to automate the generation of assay-ready plates directly from newly submitted and cherry-picked compounds. A key feature of the system is the ability to create project- or assay-specific compound-handling methods, which provide flexibility for any combination of plate types, layouts, and plate bar-codes. Project-specific workflows can be created by linking methods for processing new and cherry-picked compounds and control additions to produce a complete compound set for both biological testing and local storage in one uninterrupted workflow. A flexible cherry-pick approach allows for multiple, user-defined strategies to select the most appropriate replicate of a compound for retesting. Examples of custom selection parameters include available volume, compound batch, and number of freeze/thaw cycles. This adaptable and integrated combination of software and hardware provides a basis for reducing cycle time, fully automating compound processing, and ultimately increasing the rate at which accurate, biologically relevant results can be produced for compounds of interest in the lead optimization process.

  2. Optimal Solution for VLSI Physical Design Automation Using Hybrid Genetic Algorithm

    Directory of Open Access Journals (Sweden)

    I. Hameem Shanavas

    2014-01-01

    Full Text Available In Optimization of VLSI Physical Design, area minimization and interconnect length minimization is an important objective in physical design automation of very large scale integration chips. The objective of minimizing the area and interconnect length would scale down the size of integrated chips. To meet the above objective, it is necessary to find an optimal solution for physical design components like partitioning, floorplanning, placement, and routing. This work helps to perform the optimization of the benchmark circuits with the above said components of physical design using hierarchical approach of evolutionary algorithms. The goal of minimizing the delay in partitioning, minimizing the silicon area in floorplanning, minimizing the layout area in placement, minimizing the wirelength in routing has indefinite influence on other criteria like power, clock, speed, cost, and so forth. Hybrid evolutionary algorithm is applied on each of its phases to achieve the objective. Because evolutionary algorithm that includes one or many local search steps within its evolutionary cycles to obtain the minimization of area and interconnect length. This approach combines a hierarchical design like genetic algorithm and simulated annealing to attain the objective. This hybrid approach can quickly produce optimal solutions for the popular benchmarks.

  3. Wearable design issues for electronic vision enhancement systems

    Science.gov (United States)

    Dvorak, Joe

    2006-09-01

    As the baby boomer generation ages, visual impairment will overtake a significant portion of the US population. At the same time, more and more of our world is becoming digital. These two trends, coupled with the continuing advances in digital electronics, argue for a rethinking in the design of aids for the visually impaired. This paper discusses design issues for electronic vision enhancement systems (EVES) [R.C. Peterson, J.S. Wolffsohn, M. Rubinstein, et al., Am. J. Ophthalmol. 136 1129 (2003)] that will facilitate their wearability and continuous use. We briefly discuss the factors affecting a person's acceptance of wearable devices. We define the concept of operational inertia which plays an important role in our design of wearable devices and systems. We then discuss how design principles based upon operational inertia can be applied to the design of EVES.

  4. Reliability Oriented Circuit Design For Power Electronics Applications

    DEFF Research Database (Denmark)

    Sintamarean, Nicolae Cristian

    for improving the reliability is by active thermal control of the power electronic devices. The work developed during the Ph.D. studies the above mentioned topics, and is divided into two main parts: the first part develops a reliability-oriented design tool which is using a long term real-field mission....... The temperature variation of the semiconductor devices plays a key role in the robustness design and reliability of power electronics converters. This factor has a major impact on the power converters used in renewable energy systems, like solar and wind energy applications, due to the fluctuating nature......-profile as input and the second part propose an advanced gatedriver concept for enhancing the reliability of the power electronics devices. Chapter 1 introduce the emerging challenges of a design tool for reliability and which are the main methods for achieving active thermal control of the devices. To overcome...

  5. Crystallographic analysis of the solid-state dewetting of polycrystalline gold film using automated indexing in a transmission electron microscope

    Directory of Open Access Journals (Sweden)

    S. A. Jang

    2015-12-01

    Full Text Available We analyzed the effect of crystallographic anisotropy on the morphological evolution of a 12-nm-thick gold film during solid-state dewetting at high temperatures using automated indexing tool in a transmission electron microscopy. Dewetting initiated at grain-boundary triple junctions adjacent to large grains resulting from abnormal grain growth driven by (111 texture development. Voids at the junctions developed shapes with faceted edges bounded by low-index crystal planes. The kinetic mobility of the edges varied with the crystal orientation normal to the edges, with a predominance of specific edges with the slowest retraction rates as the annealing time was increased.

  6. Crystallographic analysis of the solid-state dewetting of polycrystalline gold film using automated indexing in a transmission electron microscope

    Energy Technology Data Exchange (ETDEWEB)

    Jang, S. A.; Lee, H. J.; Oh, Y. J., E-mail: yjoh@hanbat.ac.kr [Department of Advanced Materials Science and Engineering, Hanbat National University, 125, Dongseo-daero, Yuseong-gu, Daejeon 305-719 (Korea, Republic of); Thompson, C. V.; Ross, C. A., E-mail: caross@mit.edu [Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)

    2015-12-01

    We analyzed the effect of crystallographic anisotropy on the morphological evolution of a 12-nm-thick gold film during solid-state dewetting at high temperatures using automated indexing tool in a transmission electron microscopy. Dewetting initiated at grain-boundary triple junctions adjacent to large grains resulting from abnormal grain growth driven by (111) texture development. Voids at the junctions developed shapes with faceted edges bounded by low-index crystal planes. The kinetic mobility of the edges varied with the crystal orientation normal to the edges, with a predominance of specific edges with the slowest retraction rates as the annealing time was increased.

  7. Computer-automated tuning of semiconductor double quantum dots into the single-electron regime

    NARCIS (Netherlands)

    Baart, T.A.; Eendebak, P.T.; Reichl, C.; Wegscheider, W.; Vandersypen, L.M.K.

    2016-01-01

    We report the computer-automated tuning of gate-defined semiconductor double quantum dots in GaAs heterostructures. We benchmark the algorithm by creating three double quantum dots inside a linear array of four quantum dots. The algorithm sets the correct gate voltages for all the gates to tune the

  8. Preliminary Design Study of the Hollow Electron Lens for LHC

    CERN Document Server

    Perini, Diego; CERN. Geneva. ATS Department

    2017-01-01

    A Hollow Electron Lens (HEL) has been proposed in order to improve performance of halo control and collimation in the Large Hadron Collider in view of its High Luminosity upgrade (HL-LHC). The concept is based on a beam of electrons that travels around the protons for a few meters. The electron beam is produced by a cathode and then guided by a strong magnetic field generated by a set of superconducting solenoids. The first step of the design is the definition of the magnetic fields that drive the electron trajectories. The estimation of such trajectories by means of a dedicated MATLAB® tool is presented. The influence of the main geometrical and electrical parameters are analysed and discussed. Then, the main mechanical design choices for the solenoids, cryostats gun and collector are described. The aim of this paper is to provide an overview of the preliminary design of the Electron Lens for LHC. The methods used in this study also serve as examples for future mechanical and integration designs of similar ...

  9. Electron Accelerator Shielding Design of KIPT Neutron Source Facility

    Directory of Open Access Journals (Sweden)

    Zhaopeng Zhong

    2016-06-01

    Full Text Available The Argonne National Laboratory of the United States and the Kharkov Institute of Physics and Technology of the Ukraine have been collaborating on the design, development and construction of a neutron source facility at Kharkov Institute of Physics and Technology utilizing an electron-accelerator-driven subcritical assembly. The electron beam power is 100 kW using 100-MeV electrons. The facility was designed to perform basic and applied nuclear research, produce medical isotopes, and train nuclear specialists. The biological shield of the accelerator building was designed to reduce the biological dose to less than 5.0e-03 mSv/h during operation. The main source of the biological dose for the accelerator building is the photons and neutrons generated from different interactions of leaked electrons from the electron gun and the accelerator sections with the surrounding components and materials. The Monte Carlo N-particle extended code (MCNPX was used for the shielding calculations because of its capability to perform electron-, photon-, and neutron-coupled transport simulations. The photon dose was tallied using the MCNPX calculation, starting with the leaked electrons. However, it is difficult to accurately tally the neutron dose directly from the leaked electrons. The neutron yield per electron from the interactions with the surrounding components is very small, ∼0.01 neutron for 100-MeV electron and even smaller for lower-energy electrons. This causes difficulties for the Monte Carlo analyses and consumes tremendous computation resources for tallying the neutron dose outside the shield boundary with an acceptable accuracy. To avoid these difficulties, the SOURCE and TALLYX user subroutines of MCNPX were utilized for this study. The generated neutrons were banked, together with all related parameters, for a subsequent MCNPX calculation to obtain the neutron dose. The weight windows variance reduction technique was also utilized for both

  10. EcoDesign 2.0 - Quantitative EcoDesign within Drives and Automation Technologies

    OpenAIRE

    Auer, Johannes; Bey, Niki; Hauschild, Michael Zwicky; Wegener, Dieter

    2017-01-01

    The PhD project has its research background mainly in the fields of product development & design, manufacturing systems and quantitative sustainability assessment, incl. environmental Life Cycle Assessment (LCA). Related organizational and management research is also drawn upon as well as systems engineering approaches. Research focus lies in areas where these fields overlap and complement each other in the development process of given applications, in particular the development and imple...

  11. Software package to automate the design and production of translucent building structures made of pvc

    Directory of Open Access Journals (Sweden)

    Petrova Irina Yur’evna

    2016-08-01

    Full Text Available The article describes the features of the design and production of translucent building structures made of PVC. The analysis of the automation systems of this process currently existing on the market is carried out, their advantages and disadvantages are identified. Basing on this analysis, a set of requirements for automation systems for the design and production of translucent building structures made of PVC is formulated; the basic entities are involved in those business processes. The necessary functions for the main application and for dealers’ application are specified. The main application is based on technological platform 1C: Enterprise 8.2. The dealers’ module is .NET application and is developed with the use of Microsoft Visual Studio and Microsoft SQL Server because these software products have client versions free for end users (.NET Framework 4.0 Client Profile and Microsoft SQL Server 2008 Express. The features of the developed software complex implementation are described; the relevant charts are given. The scheme of system deployment and protocols of data exchange between 1C server, 1C client and dealer is presented. Also the functions supported by 1C module and .NET module are described. The article describes the content of class library developed for .NET module. The specification of integration of the two applications in a single software package is given. The features of the GUI organization are described; the corresponding screenshots are given. The possible ways of further development of the described software complex are presented and a conclusion about its competitiveness and expediency of new researches is made.

  12. Automated Work Package: Initial Wireless Communication Platform Design, Development, and Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Al Rashdan, Ahmad Yahya Mohammad [Idaho National Laboratory; Agarwal, Vivek [Idaho National Laboratory

    2016-03-01

    The Department of Energy’s Light Water Reactor Sustainability Program is developing the scientific basis to ensure long-term reliability, productivity, safety, and security of the nuclear power industry in the United States. The Instrumentation, Information, and Control (II&C) pathway of the program aims to increase the role of advanced II&C technologies to achieve this objective. One of the pathway efforts at Idaho National Laboratory (INL) is to improve the work packages execution process by replacing the expensive, inefficient, bulky, complex, and error-prone paper-based work orders with automated work packages (AWPs). An AWP is an automated and dynamic presentation of the work package designed to guide the user through the work process. It is loaded on a mobile device, such as a tablet, and is capable of communicating with plant equipment and systems to acquire plant and procedure states. The AWP replaces those functions where a computer is more efficient and reliable than a human. To enable the automatic acquisition of plant data, it is necessary to design and develop a prototype platform for data exchange between the field instruments and the AWP mobile devices. The development of the platform aims to reveal issues and solutions generalizable to large-scale implementation of a similar system. Topics such as bandwidth, robustness, response time, interference, and security are usually associated with wireless communication. These concerns, along with other requirements, are listed in an earlier INL report. Specifically, the targeted issues and performance aspects in this work are relevant to the communication infrastructure from the perspective of promptness, robustness, expandability, and interoperability with different technologies.

  13. Design of electron beam accelerator for microwave application

    Science.gov (United States)

    Prestwich, K. R.

    Relativistic electron beams are used for generating high power microwaves. These microwave sources require electron beam generators spanning significant ranges in voltage and impedance. The pulsed power technology used to generate these electron beams is presented. Electron beam generators that produce beams with pulse durations in the 10 ns to 100 ns regime consist of an energy storage section, pulse shaping section, and an electron beam diode. The energy storage section is either a Marx generator or capacitor bank-pulsed transformer. The pulse shaping is done with high-voltage transmission lines. The electron beam diode is usually a cold-cathode, space-charge-limited flow device. For longer pulses (approx 1 microsec) the energy storage and pulse shaping can be combined. Lumped-element pulsed-forming networks (PFN) can be designed to produce the desired pulse shape. The Marx generator becomes one of the elements of the PFN. Alternatively, a low voltage PFN followed by a highly coupled transformer can be used. Basic design principles for all of the above subsystems are discussed. Both PFLs and PFNs can also be operated as inductive storage systems with opening switches.

  14. Computer-aided design of microfluidic very large scale integration (mVLSI) biochips design automation, testing, and design-for-testability

    CERN Document Server

    Hu, Kai; Ho, Tsung-Yi

    2017-01-01

    This book provides a comprehensive overview of flow-based, microfluidic VLSI. The authors describe and solve in a comprehensive and holistic manner practical challenges such as control synthesis, wash optimization, design for testability, and diagnosis of modern flow-based microfluidic biochips. They introduce practical solutions, based on rigorous optimization and formal models. The technical contributions presented in this book will not only shorten the product development cycle, but also accelerate the adoption and further development of modern flow-based microfluidic biochips, by facilitating the full exploitation of design complexities that are possible with current fabrication techniques. Offers the first practical problem formulation for automated control-layer design in flow-based microfluidic biochips and provides a systematic approach for solving this problem; Introduces a wash-optimization method for cross-contamination removal; Presents a design-for-testability (DfT) technique that can achieve 100...

  15. Designing an Electronic Educational Game to Facilitate Immersion and Flow

    Science.gov (United States)

    Ma, Yuxin; Williams, Doug; Prejean, Louise

    2014-01-01

    Advocates of electronic educational games often cite the work on motivation to support the use of games in education. However, motivation alone is inadequate to facilitate learning. Many of the educational games that focused their game design solely on the motivational effect failed to be either educational or entertaining. Theory and research is…

  16. Agent Mediated Electronic Commerce: Designing Trading Agents and Mechanisms

    NARCIS (Netherlands)

    J.A. La Poutré (Han); N.M. Sadeh; S. Janson

    2006-01-01

    htmlabstractThis book constitutes the thoroughly refereed post-proceedings of the 7th International Workshop on Agent-Mediated Electronic Commerce, AMEC VII 2005, held in Utrecht, Netherlands in July 2005, as part of AAMAS 2005, and the third Workshop on Trading Agent Design and Analysis, TADA 2005,

  17. De novo automated design of small RNA circuits for engineering synthetic riboregulation in living cells.

    Science.gov (United States)

    Rodrigo, Guillermo; Landrain, Thomas E; Jaramillo, Alfonso

    2012-09-18

    A grand challenge in synthetic biology is to use our current knowledge of RNA science to perform the automatic engineering of completely synthetic sequences encoding functional RNAs in living cells. We report here a fully automated design methodology and experimental validation of synthetic RNA interaction circuits working in a cellular environment. The computational algorithm, based on a physicochemical model, produces novel RNA sequences by exploring the space of possible sequences compatible with predefined structures. We tested our methodology in Escherichia coli by designing several positive riboregulators with diverse structures and interaction models, suggesting that only the energy of formation and the activation energy (free energy barrier to overcome for initiating the hybridization reaction) are sufficient criteria to engineer RNA interaction and regulation in bacteria. The designed sequences exhibit nonsignificant similarity to any known noncoding RNA sequence. Our riboregulatory devices work independently and in combination with transcription regulation to create complex logic circuits. Our results demonstrate that a computational methodology based on first-principles can be used to engineer interacting RNAs with allosteric behavior in living cells.

  18. An optimization design proposal of automated guided vehicles for mixed type transportation in hospital environments.

    Science.gov (United States)

    González, Domingo; Romero, Luis; Espinosa, María Del Mar; Domínguez, Manuel

    2017-01-01

    The aim of this paper is to present an optimization proposal in the automated guided vehicles design used in hospital logistics, as well as to analyze the impact of its implementation in a real environment. This proposal is based on the design of those elements that would allow the vehicles to deliver an extra cart by the towing method. So, the proposal intention is to improve the productivity and the performance of the current vehicles by using a transportation method of combined carts. The study has been developed following concurrent engineering premises from three different viewpoints. First, the sequence of operations has been described, and second, a proposal of design of the equipment has been undertaken. Finally, the impact of the proposal has been analyzed according to real data from the Hospital Universitario Rio Hortega in Valladolid (Spain). In this particular case, by the implementation of the analyzed proposal in the hospital a reduction of over 35% of the current time of use can be achieved. This result may allow adding new tasks to the vehicles, and according to this, both a new kind of vehicle and a specific module can be developed in order to get a better performance.

  19. Designing the Electronic Classroom: Applying Learning Theory and Ergonomic Design Principles.

    Science.gov (United States)

    Emmons, Mark; Wilkinson, Frances C.

    2001-01-01

    Applies learning theory and ergonomic principles to the design of effective learning environments for library instruction. Discusses features of electronic classroom ergonomics, including the ergonomics of physical space, environmental factors, and workstations; and includes classroom layouts. (Author/LRW)

  20. Influence of operating frequency on design of power electronic transformers

    Science.gov (United States)

    Valchev, V. C.; Van den Bossche, A.; Todorova, T. P.

    2017-10-01

    The influence of operating frequency on parameters of power electronic transformers is investigated. An improved fast design algorithm is used to calculate competitive transformer designs based on ferrite cores and round wires under the same input parameters, while varying the operating frequency in a wide range (25 kHz to 400 kHz). Two sets of designs are compared: for a 400W and a1200W full bridge converter. Specific optimization approaches are proposed to decrease eddy current losses in wires by interleaving windings.

  1. Design of Electronic Clock based on STM32

    Science.gov (United States)

    Huang, Jian

    2017-09-01

    This paper describes the design method of electronic clock based on STM32. The hardware circuit is designed, which uses the built-in RTC module of the STM32, and the backup battery is used to supply power. When first programming, the current date and time is wrote, after that the RTC module will automatically count. It also can be used to set the alarm time. Software programming can read the current time and conversion it, then it will be displayed on the LCD screen. The test results show that the design has the advantages of accurate timing, high reliability and long service life.

  2. What do information reuse and automated processing require in engineering design? Semantic process

    Directory of Open Access Journals (Sweden)

    Ossi Nykänen

    2011-12-01

    Full Text Available Purpose: The purpose of this study is to characterize, analyze, and demonstrate machine-understandable semantic process for validating, integrating, and processing technical design information. This establishes both a vision and tools for information reuse and semi-automatic processing in engineering design projects, including virtual machine laboratory applications with generated components.Design/methodology/approach: The process model has been developed iteratively in terms of action research, constrained by the existing technical design practices and assumptions (design documents, expert feedback, available technologies (pre-studies and experiments with scripting and pipeline tools, benchmarking with other process models and methods (notably the RUP and DITA, and formal requirements (computability and the critical information paths for the generated applications. In practice, the work includes both quantitative and qualitative components.Findings: Technical design processes may be greatly enhanced in terms of semantic process thinking, by enriching design information, and automating information validation and transformation tasks. Contemporary design information, however, is mainly intended for human consumption, and needs to be explicitly enriched with the currently missing data and interfaces. In practice, this may require acknowledging the role of technical information or knowledge engineer, to lead the development of the semantic design information process in a design organization. There is also a trade-off between machine-readability and system complexity that needs to be studied further, both empirically and in theory.Research limitations/implications: The conceptualization of the semantic process is essentially an abstraction based on the idea of progressive design. While this effectively allows implementing semantic processes with, e.g., pipeline technologies, the abstraction is valid only when technical design is organized into

  3. Mechanical design of an electronic control unit using axiomatic principles

    Directory of Open Access Journals (Sweden)

    Cazacu Vlad

    2017-01-01

    Full Text Available If the engine of the car can be considered as the heart, then the E.C.U’s represents the brain of the car. Electronic control units (E.C.U’s are electronic devices which control the way different components of a car (engine, windows, airbags, etc. react in some situations (overheating, button pressed by a passenger, crash, etc.. Axiomatic design is a set of principles that theorizes the act of conceiving a new project. Based on two axiom this method comes into designers help, giving them the option to reach in a short period of time a fully functional and compliant product without supporting the design of the product on chance, past experiences or “try and fail” principle.

  4. Design of wormlike automated robotic endoscope: dynamic interaction between endoscopic balloon and surrounding tissues.

    Science.gov (United States)

    Poon, Carmen C Y; Leung, Billy; Chan, Cecilia K W; Lau, James Y W; Chiu, Philip W Y

    2016-02-01

    The current design of capsule endoscope is limited by the inability to control the motion within gastrointestinal tract. The rising incidence of gastrointestinal cancers urged improvement in the method of screening endoscopy. This preclinical study aimed to design and develop a novel locomotive module for capsule endoscope. We investigated the feasibility and physical properties of this newly designed caterpillar-like capsule endoscope with a view to enhancing screening endoscopy. This study consisted of preclinical design and experimental testing on the feasibility of automated locomotion for a prototype caterpillar endoscope. The movement was examined first in the PVC tube and then in porcine intestine. The image captured was transmitted to handheld device to confirm the control of movement. The balloon pressure and volume as well as the contact force between the balloon and surroundings were measured when the balloon was inflated inside (1) a hard PVC tube, (2) a soft PVC tube, (3) muscular sites of porcine colons and (4) less muscular sites of porcine colons. The prototype caterpillar endoscope was able to move inward and backward within the PVC tubing and porcine intestine. Images were able to be captured from the capsule endoscope attached and being observed with a handheld device. Using the onset of a contact force as indication of the buildup of the gripping force between the balloon and the lumen walls, it is concluded from the results of this study that the rate of change in balloon pressure and volume is two good estimators to optimize the inflation of the balloon. The results of this study will facilitate further refinement in the design of caterpillar robotic endoscope to move inside the GI tract.

  5. Automated degenerate PCR primer design for high-throughput sequencing improves efficiency of viral sequencing

    Directory of Open Access Journals (Sweden)

    Li Kelvin

    2012-11-01

    Full Text Available Abstract Background In a high-throughput environment, to PCR amplify and sequence a large set of viral isolates from populations that are potentially heterogeneous and continuously evolving, the use of degenerate PCR primers is an important strategy. Degenerate primers allow for the PCR amplification of a wider range of viral isolates with only one set of pre-mixed primers, thus increasing amplification success rates and minimizing the necessity for genome finishing activities. To successfully select a large set of degenerate PCR primers necessary to tile across an entire viral genome and maximize their success, this process is best performed computationally. Results We have developed a fully automated degenerate PCR primer design system that plays a key role in the J. Craig Venter Institute’s (JCVI high-throughput viral sequencing pipeline. A consensus viral genome, or a set of consensus segment sequences in the case of a segmented virus, is specified using IUPAC ambiguity codes in the consensus template sequence to represent the allelic diversity of the target population. PCR primer pairs are then selected computationally to produce a minimal amplicon set capable of tiling across the full length of the specified target region. As part of the tiling process, primer pairs are computationally screened to meet the criteria for successful PCR with one of two described amplification protocols. The actual sequencing success rates for designed primers for measles virus, mumps virus, human parainfluenza virus 1 and 3, human respiratory syncytial virus A and B and human metapneumovirus are described, where >90% of designed primer pairs were able to consistently successfully amplify >75% of the isolates. Conclusions Augmenting our previously developed and published JCVI Primer Design Pipeline, we achieved similarly high sequencing success rates with only minor software modifications. The recommended methodology for the construction of the consensus

  6. Intensification of the Learning Process: Automated Instructional Resources Retrieval System. A Series of Reports Designed for Classroom Use.

    Science.gov (United States)

    Bucks County Public Schools, Doylestown, PA.

    The problem of finding relevant material to answer a classroom need is the focus of this report. The Automated Instructional Resources Retrieval System (AIRR) is designed to assist teachers by storing information in a number of categories, including the following: media type, maturity level, length, producer or publisher, main curriculum area,…

  7. A methodological approach for the optimisation of the product development process by the application of design automation

    NARCIS (Netherlands)

    Mulder, B.; La Rocca, G.; Schut, J.; Verhagen, W.J.C.

    2015-01-01

    A short lead time of the Product Development Process (PDP) is an important competitive advantage for companies. Design automation solutions provide a means to reduce the lead time and improve quality, but their development requires some investment. Before a company can commit to the development of

  8. Integrated Design and Analysis Environment for Safety Critical Human-Automation Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Flight deck systems, like many safety critical systems, often involve complex interactions between multiple human operators, automated subsystems, and physical...

  9. Innovative Mobile Platform Developments for Electronic Services Design and Delivery

    DEFF Research Database (Denmark)

    Scupola, Ada

    In the ever-growing world of technology, it is becoming more important to understand the developments of new electronic services and mobile applications. Innovative Mobile Platform Developments for Electronic Services Design, and Delivery is a comprehensive look at all aspects of production...... management, delivery and consumption of e-services, self services, and mobile communication including business-to-business, business-to-consumer, government-to-business, government-to-consumer, and consumer-to-consumer e-services. This volume is perfect for the interest of professionals, academic educators...

  10. A Multi-Agent-Based Intelligent Sensor and Actuator Network Design for Smart House and Home Automation

    Directory of Open Access Journals (Sweden)

    Fei Hu

    2013-08-01

    Full Text Available The smart-house technology aims to increase home automation and security with reduced energy consumption. A smart house consists of various intelligent sensors and actuators operating on different platforms with conflicting objectives. This paper proposes a multi-agent system (MAS design framework to achieve smart house automation. The novelties of this work include the developments of (1 belief, desire and intention (BDI agent behavior models; (2 a regulation policy-based multi-agent collaboration mechanism; and (3 a set of metrics for MAS performance evaluation. Simulations of case studies are performed using the Java Agent Development Environment (JADE to demonstrate the advantages of the proposed method.

  11. System Design and Development of a Robotic Device for Automated Venipuncture and Diagnostic Blood Cell Analysis.

    Science.gov (United States)

    Balter, Max L; Chen, Alvin I; Fromholtz, Alex; Gorshkov, Alex; Maguire, Tim J; Yarmush, Martin L

    2016-10-01

    Diagnostic blood testing is the most prevalent medical procedure performed in the world and forms the cornerstone of modern health care delivery. Yet blood tests are still predominantly carried out in centralized labs using large-volume samples acquired by manual venipuncture, and no end-to-end solution from blood draw to sample analysis exists today. Our group is developing a platform device that merges robotic phlebotomy with automated diagnostics to rapidly deliver patient information at the site of the blood draw. The system couples an image-guided venipuncture robot, designed to address the challenges of routine venous access, with a centrifuge-based blood analyzer to obtain quantitative measurements of hematology. In this paper, we first present the system design and architecture of the integrated device. We then perform a series of in vitro experiments to evaluate the cannulation accuracy of the system on blood vessel phantoms. Next, we assess the effects of vessel diameter, needle gauge, flow rate, and viscosity on the rate of sample collection. Finally, we demonstrate proof-of-concept of a white cell assay on the blood analyzer using in vitro human samples spiked with fluorescently labeled microbeads.

  12. System design and verification process for LHC programmable trigger electronics

    CERN Document Server

    Crosetto, D

    1999-01-01

    The rapid evolution of electronics has made it essential to design systems in a technology-independent form that will permit their realization in any future technology. This article describes two practical projects that have been developed for fast, programmable, scalable, modular electronics for the first-level trigger of Large Hadron Collider (LHC) experiments at CERN, Geneva. In both projects, one for the front-end electronics and the second for executing first- level trigger algorithms, the whole system requirements were constrained to two types of replicated components. The overall problem is described, the 3D-Flow design is introduced as a novel solution, and current solutions to the problem are described and compared with the 3D-Flow solution. The design/verification methodology proposed allows the user's real-time system algorithm to be verified down to the gate-level simulation on a technology- independent platform, thus yielding the design for a system that can be implemented with any technology at ...

  13. Design, analysis and modeling of a novel hybrid powertrain system based on hybridized automated manual transmission

    Science.gov (United States)

    Wu, Guang; Dong, Zuomin

    2017-09-01

    Hybrid electric vehicles are widely accepted as a promising short to mid-term technical solution due to noticeably improved efficiency and lower emissions at competitive costs. In recent years, various hybrid powertrain systems were proposed and implemented based on different types of conventional transmission. Power-split system, including Toyota Hybrid System and Ford Hybrid System, are well-known examples. However, their relatively low torque capacity, and the drive of alternative and more advanced designs encouraged other innovative hybrid system designs. In this work, a new type of hybrid powertrain system based hybridized automated manual transmission (HAMT) is proposed. By using the concept of torque gap filler (TGF), this new hybrid powertrain type has the potential to overcome issue of torque gap during gearshift. The HAMT design (patent pending) is described in details, from gear layout and design of gear ratios (EV mode and HEV mode) to torque paths at different gears. As an analytical tool, mutli-body model of vehicle equipped with this HAMT was built to analyze powertrain dynamics at various steady and transient modes. A gearshift was decomposed and analyzed based basic modes. Furthermore, a Simulink-SimDriveline hybrid vehicle model was built for the new transmission, driveline and vehicle modular. Control strategy has also been built to harmonically coordinate different powertrain components to realize TGF function. A vehicle launch simulation test has been completed under 30% of accelerator pedal position to reveal details during gearshift. Simulation results showed that this HAMT can eliminate most torque gap that has been persistent issue of traditional AMT, improving both drivability and performance. This work demonstrated a new type of transmission that features high torque capacity, high efficiency and improved drivability.

  14. INTERACTION REGION DESIGN FOR THE ELECTRON-ION COLLIDER ERHIC.

    Energy Technology Data Exchange (ETDEWEB)

    MONTAG, C.; PARKER, B.; TEPIKIAN, S.; ET AL.

    2005-05-16

    To facilitate the study of collisions between 10 GeV polarized electrons and 100 GeV/u heavy ions or 250 GeV polarized protons at luminosities in the 10{sup 33} cm{sup -2} sec{sup -1} range (e-p case), adding a 10 GeV electron storage ring to the existing RHIC complex has been proposed. The interaction region of this electron-ion collider eRHIC has to provide the required low-beta focusing, while simultaneously accommodating the synchrotron radiation fan generated by beam separation close to the interaction point, which is particularly challenging. The latest design status of the eRHIC interaction region will be presented.

  15. Conceptual design of industrial free electron laser using superconducting accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Saldin, E.L.; Schneidmiller, E.A.; Ulyanov, Yu.N. [Automatic Systems Corporation, Samara (Russian Federation)] [and others

    1995-12-31

    Paper presents conceptual design of free electron laser (FEL) complex for industrial applications. The FEL complex consists of three. FEL oscillators with the optical output spanning the infrared (IR) and ultraviolet (UV) wave-lengths ({lambda} = 0.3...20 {mu}m) and with the average output power 10 - 20 kW. The driving beam for the FELs is produced by a superconducting accelerator. The electron beam is transported to the FELs via three beam lines (125 MeV and 2 x 250 MeV). Peculiar feature of the proposed complex is a high efficiency of the. FEL oscillators, up to 20 %. This becomes possible due to the use of quasi-continuous electron beam and the use of the time-dependent undulator tapering.

  16. Design Considerations for Optimized Lateral Spring Structures for Wearable Electronics

    KAUST Repository

    Hussain, Aftab M.

    2016-03-07

    The market for wearable electronics has been gaining momentum in the recent years. For completely electronic wearable textiles with integrated sensors, actuators, computing units and communication circuitry, it is important that there is significant stretchability. This stretchability can be obtained by introducing periodic stretchable structures between the electronic circuits. In this work, we derive the equations and constraints governing the stretchability in horseshoe lateral spring structures. We have derived the optimum design and the parameters therein, to help develop the best spring structures for a given stretchability. We have also developed a figure of merit, called area efficiency of stretchability, to compare all twodimensional stretchable systems. Finally, we experimentally verify the validity of our equations by fabricating a metal/polymer bilayer thin film based stretchable horseshoe lateral spring structures. We obtain a stretchability of 1.875 which is comparable to the theoretical maxima of 2.01 for the given parameters.

  17. Automation of specimen selection and data acquisition for protein electron crystallography

    NARCIS (Netherlands)

    Oostergetel, G.T.; Keegstra, W.; Brisson, A.D R

    A system is presented for semi-automatic specimen selection and data acquisition for protein electron crystallography, based on a slow-scan CCD camera connected to a transmission electron microscope and control from an external computer. Areas of interest on the specimen are localised at low

  18. Improving Usefulness of Automated Driving by Lowering Primary Task Interference through HMI Design

    Directory of Open Access Journals (Sweden)

    Frederik Naujoks

    2017-01-01

    Full Text Available During conditionally automated driving (CAD, driving time can be used for non-driving-related tasks (NDRTs. To increase safety and comfort of an automated ride, upcoming automated manoeuvres such as lane changes or speed adaptations may be communicated to the driver. However, as the driver’s primary task consists of performing NDRTs, they might prefer to be informed in a nondistracting way. In this paper, the potential of using speech output to improve human-automation interaction is explored. A sample of 17 participants completed different situations which involved communication between the automation and the driver in a motion-based driving simulator. The Human-Machine Interface (HMI of the automated driving system consisted of a visual-auditory HMI with either generic auditory feedback (i.e., standard information tones or additional speech output. The drivers were asked to perform a common NDRT during the drive. Compared to generic auditory output, communicating upcoming automated manoeuvres additionally by speech led to a decrease in self-reported visual workload and decreased monitoring of the visual HMI. However, interruptions of the NDRT were not affected by additional speech output. Participants clearly favoured the HMI with additional speech-based output, demonstrating the potential of speech to enhance usefulness and acceptance of automated vehicles.

  19. Design considerations on user-interaction for semi-automated driving

    NARCIS (Netherlands)

    van den Beukel, Arie Paul; van der Voort, Mascha C.

    2015-01-01

    The automotive industry has recently made first steps towards implementation of automated driving, by introducing lateral control as addition to longitudinal control (i.e. ACC). This automated control is allowed during specific situations within existing infrastructure (e.g. motorway cruising).

  20. Ecological interface design : supporting fault diagnosis of automated advice in a supervisory air traffic control task

    NARCIS (Netherlands)

    Borst, C.; Bijsterbosch, V.A.; van Paassen, M.M.; Mulder, M.

    2017-01-01

    Future air traffic control will have to rely on more advanced automation to support human controllers in their job of safely handling increased traffic volumes. A prerequisite for the success of such automation is that the data driving it are reliable. Current technology, however, still warrants

  1. Design studies for the electron storage ring EUTERPE

    Energy Technology Data Exchange (ETDEWEB)

    Xi Boling

    1995-05-18

    The 400 MeV electron storage ring EUTERPE is under construction at Eindhoven University of Technology. The ring is to be used as an experimental tool for accelerator physics studies and synchroton radiation applications. The main task of the current research work is the electron optical design of the ring. Lattice design is a basis for machine design as a whole. Design aspects regarding the basic lattice, based on single particle dynamics, include determination of the equilibrium beam size and bunch length, design of achromatic bending sections, selection of tune values, correction of chromaticity, and minimization of the natural emittance in the ring. The basic lattice designed for the EUTERPE ring has a high flexibility so that different electron optical modes can be realized easily. In low energy storage rings with a high beam current, collective effects can cause a significant change in the bunch length, the transverse emittance and the beam lifetime. In order to ensure a good optical performance for the ring, the choice of suitable parameters concerning the vacuum and RF system are essential as far as collective effects are concerned. An estimation of the collective effects in the ring is given. The injector for EUTERPE is a 75 MeV racetrack microtron which is injected from a 10 MeV linac. In order to get sufficient beam current in the ring, a special procedure of continuous injection with an adjustable locally shifted closed orbit has been presented. Details of the injection procedure and numerical simulations are given. (orig./HSI).

  2. Electronic structure design for nanoporous, electrically conductive zeolitic imidazolate frameworks

    OpenAIRE

    Butler, Keith T.; Worrall, Stephen D.; Molloy, Christopher D.; Hendon, Christopher H.; Attfield, Martin P.; Dryfe, Robert A.W.; Walsh, Aron

    2017-01-01

    Electronic structure calculations are used to develop design rules for enhanced electrical conductivity in zeolitic imidazolate frameworks. The electrical resistivity of Co2+ based zeolitic imidazolate frameworks has previously been found to be ∼1000 times lower than that of Zn2+ based materials. The electrical conductivity of the frameworks can also be tuned by ligand molecule selection. Using density functional theory calculations, this controllable electrical conductivity is explained in t...

  3. Improved Standard Electronic Modules, Thermal and Mechanical Analyses and Design

    Science.gov (United States)

    1978-09-01

    center frame. For greater detail on the computer solution to the Comuter -Aided Thermal Modeling, refer to Standard Electronic Modules Exploratory... solutions were obtained for all frame designs and component layout configurations using three metal alloys having different thermal conductivities...as a heat conducting element, was neglected. Concerning this, a separate computer solution was made considering the ISEM fin top as being .270 inch

  4. Transformers and inductors for power electronics theory, design and applications

    CERN Document Server

    Hurley, WG

    2013-01-01

    Based on the fundamentals of electromagnetics, this clear and concise text explains basic and applied principles of transformer and inductor design for power electronic applications. It details both the theory and practice of inductors and transformers employed to filter currents, store electromagnetic energy, provide physical isolation between circuits, and perform stepping up and down of DC and AC voltages. The authors present a broad range of applications from modern power conversion systems. They provide rigorous design guidelines based on a robust methodology for inductor and transform

  5. Development and validation of an automated ventilator-associated event electronic surveillance system: A report of a successful implementation.

    Science.gov (United States)

    Hebert, Courtney; Flaherty, Jennifer; Smyer, Justin; Ding, Jing; Mangino, Julie E

    2017-11-10

    Surveillance is an important tool for infection control; however, this task can often be time-consuming and take away from infection prevention activities. With the increasing availability of comprehensive electronic health records, there is an opportunity to automate these surveillance activities. The objective of this article is to describe the implementation of an electronic algorithm for ventilator-associated events (VAEs) at a large academic medical center METHODS: This article reports on a 6-month manual validation of a dashboard for VAEs. We developed a computerized algorithm for automatically detecting VAEs and compared the output of this algorithm to the traditional, manual method of VAE surveillance. Manual surveillance by the infection preventionists identified 13 possible and 11 probable ventilator-associated pneumonias (VAPs), and the VAE dashboard identified 16 possible and 13 probable VAPs. The dashboard had 100% sensitivity and 100% accuracy when compared with manual surveillance for possible and probable VAP. We report on the successfully implemented VAE dashboard. Workflow of the infection preventionists was simplified after implementation of the dashboard with subjective time-savings reported. Implementing a computerized dashboard for VAE surveillance at a medical center with a comprehensive electronic health record is feasible; however, this required significant initial and ongoing work on the part of data analysts and infection preventionists. Copyright © 2017 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Elsevier Inc. All rights reserved.

  6. Stochastic Micro-Pattern for Automated Correlative Fluorescence - Scanning Electron Microscopy

    Science.gov (United States)

    Begemann, Isabell; Viplav, Abhiyan; Rasch, Christiane; Galic, Milos

    2015-01-01

    Studies of cellular surface features gain from correlative approaches, where live cell information acquired by fluorescence light microscopy is complemented by ultrastructural information from scanning electron micrographs. Current approaches to spatially align fluorescence images with scanning electron micrographs are technically challenging and often cost or time-intensive. Relying exclusively on open-source software and equipment available in a standard lab, we have developed a method for rapid, software-assisted alignment of fluorescence images with the corresponding scanning electron micrographs via a stochastic gold micro-pattern. Here, we provide detailed instructions for micro-pattern production and image processing, troubleshooting for critical intermediate steps, and examples of membrane ultra-structures aligned with the fluorescence signal of proteins enriched at such sites. Together, the presented method for correlative fluorescence – scanning electron microscopy is versatile, robust and easily integrated into existing workflows, permitting image alignment with accuracy comparable to existing approaches with negligible investment of time or capital. PMID:26647824

  7. Model-Based Design and Formal Verification Processes for Automated Waterway System Operations

    Directory of Open Access Journals (Sweden)

    Leonard Petnga

    2016-06-01

    Full Text Available Waterway and canal systems are particularly cost effective in the transport of bulk and containerized goods to support global trade. Yet, despite these benefits, they are among the most under-appreciated forms of transportation engineering systems. Looking ahead, the long-term view is not rosy. Failures, delays, incidents and accidents in aging waterway systems are doing little to attract the technical and economic assistance required for modernization and sustainability. In a step toward overcoming these challenges, this paper argues that programs for waterway and canal modernization and sustainability can benefit significantly from system thinking, supported by systems engineering techniques. We propose a multi-level multi-stage methodology for the model-based design, simulation and formal verification of automated waterway system operations. At the front-end of development, semi-formal modeling techniques are employed for the representation of project goals and scenarios, requirements and high-level models of behavior and structure. To assure the accuracy of engineering predictions and the correctness of operations, formal modeling techniques are used for the performance assessment and the formal verification of the correctness of functionality. The essential features of this methodology are highlighted in a case study examination of ship and lock-system behaviors in a two-stage lock system.

  8. An Occupancy Based Cyber-Physical System Design for Intelligent Building Automation

    Directory of Open Access Journals (Sweden)

    Kottarathil Eashy Mary Reena

    2015-01-01

    Full Text Available Cyber-physical system (CPS includes the class of Intelligent Building Automation System (IBAS which increasingly utilizes advanced technologies for long term stability, economy, longevity, and user comfort. However, there are diverse issues associated with wireless interconnection of the sensors, controllers, and power consuming physical end devices. In this paper, a novel architecture of CPS for wireless networked IBAS with priority-based access mechanism is proposed for zones in a large building with dynamically varying occupancy. Priority status of zones based on occupancy is determined using fuzzy inference engine. Nondominated Sorting Genetic Algorithm-II (NSGA-II is used to solve the optimization problem involving conflicting demands of minimizing total energy consumption and maximizing occupant comfort levels in building. An algorithm is proposed for power scheduling in sensor nodes to reduce their energy consumption. Wi-Fi with Elimination-Yield Nonpreemptive Multiple Access (EY-NPMA scheme is used for assigning priority among nodes for wireless channel access. Controller design techniques are also proposed for ensuring the stability of the closed loop control of IBAS in the presence of packet dropouts due to unreliable network links.

  9. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift

    Directory of Open Access Journals (Sweden)

    Dirk Lehmhus

    2015-12-01

    Full Text Available Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a sensor integration and thus usage information is not available on a large scale and (b product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives.

  10. A novel automated instrument designed to determine photosensitivity thresholds (Conference Presentation)

    Science.gov (United States)

    Aguilar, Mariela C.; Gonzalez, Alex; Rowaan, Cornelis; De Freitas, Carolina; Rosa, Potyra R.; Alawa, Karam; Lam, Byron L.; Parel, Jean-Marie A.

    2016-03-01

    As there is no clinically available instrument to systematically and reliably determine the photosensitivity thresholds of patients with dry eyes, blepharospasms, migraines, traumatic brain injuries, and genetic disorders such as Achromatopsia, retinitis pigmentosa and other retinal dysfunctions, a computer-controlled optoelectronics system was designed. The BPEI Photosensitivity System provides a light stimuli emitted from a bi-cupola concave, 210 white LED array with varying intensity ranging from 1 to 32,000 lux. The system can either utilize a normal or an enhanced testing mode for subjects with low light tolerance. The automated instrument adjusts the intensity of each light stimulus. The subject is instructed to indicate discomfort by pressing a hand-held button. Reliability of the responses is tracked during the test. The photosensitivity threshold is then calculated after 10 response reversals. In a preliminary study, we demonstrated that subjects suffering from Achromatopsia experienced lower photosensitivity thresholds than normal subjects. Hence, the system can safely and reliably determine the photosensitivity thresholds of healthy and light sensitive subjects by detecting and quantifying the individual differences. Future studies will be performed with this system to determine the photosensitivity threshold differences between normal subjects and subjects suffering from other conditions that affect light sensitivity.

  11. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift

    Science.gov (United States)

    Lehmhus, Dirk; Wuest, Thorsten; Wellsandt, Stefan; Bosse, Stefan; Kaihara, Toshiya; Thoben, Klaus-Dieter; Busse, Matthias

    2015-01-01

    Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives. PMID:26703606

  12. Cloud-Based Automated Design and Additive Manufacturing: A Usage Data-Enabled Paradigm Shift.

    Science.gov (United States)

    Lehmhus, Dirk; Wuest, Thorsten; Wellsandt, Stefan; Bosse, Stefan; Kaihara, Toshiya; Thoben, Klaus-Dieter; Busse, Matthias

    2015-12-19

    Integration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and evaluating product usage and life cycle data, additive manufacturing and sensor integration, automated design and cloud-based services in manufacturing. By joining and extrapolating development trends in these areas, it delimits the foundations of a manufacturing concept that will allow continuous and economically viable product optimization on a general, user group or individual user level. This projection is checked against three different application scenarios, each of which stresses different aspects of the underlying holistic concept. The following discussion identifies critical issues and research needs by adopting the relevant stakeholder perspectives.

  13. A Study on the Design of Electronic SAMG Functional Modules

    Energy Technology Data Exchange (ETDEWEB)

    Park, S. H.; Kim, J. H.; Ahn, K. I. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-10-15

    This paper describes a study on the design of e-SAMG functional modules. A study of for the design of e-SAMG was introduced. During an emergency status of a severe accident, the items for the functional module during a rapid and exact action are surveyed. The results are being implemented in e-SAMG. The operators can be supported through the use of e-SAMG. Based on the design of functional modules, the implementation will be accelerated and the refined design can also be applied. As a part of the Ministry of Science, ICT and future Planning (MSIP) Project, we at KAERI are developing electronic SAMG (e-SAMG, severe accident mitigation guideline) for general SAMG for nuclear power plants. Due to computerized trends, various efforts related to computer systems have been carried out for safety systems in nuclear power plants. In particular, since the Fukushima accident, unexpected accidents or extreme damages have become a concern. With this status, a rapid and exact confrontation such as a computerized attempt in SAMG has been tried. To develop an electronic SAMG, based on an analysis of the general SAMG, the architecture of e-SAMG was founded. The functional modules occupy important parts in the e-SAMG.

  14. A precision cryostat design for manual and semi-automated cryo-plunge instruments

    Science.gov (United States)

    Russo, Christopher J.; Scotcher, Steve; Kyte, Martin

    2016-11-01

    Here we describe a bench-top cryostat system to control the temperature of liquid ethane in a cryo-plunge apparatus designed for biological specimen preparation for electron cryomicroscopy. It comprises a foam insulated Dewar containing a copper cryostat cup, whose temperature is controlled via an active feedback system to within 0.1 K. The device can easily be incorporated into existing manual and semi-automatic cryo-plunge instruments that are not equipped with cryogenic temperature control. Over the course of normal use, we find that using a cryostat is convenient, fast, and does not require special mixtures of cryogens like ethane/propane. This simple cryostat improves the reliability and reproducibility of biological specimen preparation for electron cryomicroscopy.

  15. The Semantic Automated Discovery and Integration (SADI Web service Design-Pattern, API and Reference Implementation

    Directory of Open Access Journals (Sweden)

    Wilkinson Mark D

    2011-10-01

    Full Text Available Abstract Background The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community. Description SADI - Semantic Automated Discovery and Integration - is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services "stack", SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers. Conclusions SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behaviour we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services

  16. The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation.

    Science.gov (United States)

    Wilkinson, Mark D; Vandervalk, Benjamin; McCarthy, Luke

    2011-10-24

    The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community. SADI - Semantic Automated Discovery and Integration - is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services "stack", SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers. SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behaviour we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services can be explored in a manner very similar to data housed in

  17. The Semantic Automated Discovery and Integration (SADI) Web service Design-Pattern, API and Reference Implementation

    Science.gov (United States)

    2011-01-01

    Background The complexity and inter-related nature of biological data poses a difficult challenge for data and tool integration. There has been a proliferation of interoperability standards and projects over the past decade, none of which has been widely adopted by the bioinformatics community. Recent attempts have focused on the use of semantics to assist integration, and Semantic Web technologies are being welcomed by this community. Description SADI - Semantic Automated Discovery and Integration - is a lightweight set of fully standards-compliant Semantic Web service design patterns that simplify the publication of services of the type commonly found in bioinformatics and other scientific domains. Using Semantic Web technologies at every level of the Web services "stack", SADI services consume and produce instances of OWL Classes following a small number of very straightforward best-practices. In addition, we provide codebases that support these best-practices, and plug-in tools to popular developer and client software that dramatically simplify deployment of services by providers, and the discovery and utilization of those services by their consumers. Conclusions SADI Services are fully compliant with, and utilize only foundational Web standards; are simple to create and maintain for service providers; and can be discovered and utilized in a very intuitive way by biologist end-users. In addition, the SADI design patterns significantly improve the ability of software to automatically discover appropriate services based on user-needs, and automatically chain these into complex analytical workflows. We show that, when resources are exposed through SADI, data compliant with a given ontological model can be automatically gathered, or generated, from these distributed, non-coordinating resources - a behaviour we have not observed in any other Semantic system. Finally, we show that, using SADI, data dynamically generated from Web services can be explored in a manner

  18. Robotized semiautomatic motorcycle transmission development. Electronic and software design

    Directory of Open Access Journals (Sweden)

    Neghină Mihai

    2017-01-01

    Full Text Available In this paper, we propose an electrical design (implemented on a PCB board and an accompanying software design for controlling the automatic gear change. The designs complement the mechanical solutions developed in Part 1. The paper also analyses the issues encountered during the intermediate steps of the development of the electronic module, which is expected to be small and adaptable enough to be installed on a motorcycle without changing its ergonomics. The control software runs on the Arduino Nano board and is built as a state machine with one idle state, five active states that cover different stages of the gear change and one error state for preventing malfunctions in case of an unexpected event. The sketch uses 5,760 bytes (or 18% of program storage space and 706 bytes (or 34% of the dynamic memory.

  19. Design of materials configurations for enhanced phononic and electronic properties

    Science.gov (United States)

    Daraio, Chiara

    The discovery of novel nonlinear dynamic and electronic phenomena is presented for the specific cases of granular materials and carbon nanotubes. This research was conducted for designing and constructing optimized macro-, micro- and nano-scale structural configurations of materials, and for studying their phononic and electronic behavior. Variation of composite arrangements of granular elements with different elastic properties in a linear chain-of-sphere, Y-junction or 3-D configurations led to a variety of novel phononic phenomena and interesting physical properties, which can be potentially useful for security, communications, mechanical and biomedical engineering applications. Mechanical and electronic properties of carbon nanotubes with different atomic arrangements and microstructures were also investigated. Electronic properties of Y-junction configured carbon nanotubes exhibit an exciting transistor switch behavior which is not seen in linear configuration nanotubes. Strongly nonlinear materials were designed and fabricated using novel and innovative concepts. Due to their unique strongly nonlinear and anisotropic nature, novel wave phenomena have been discovered. Specifically, violations of Snell's law were detected and a new mechanism of wave interaction with interfaces between NTPCs (Nonlinear Tunable Phononic Crystals) was established. Polymer-based systems were tested for the first time, and the tunability of the solitary waves speed was demonstrated. New materials with transformed signal propagation speed in the manageable range of 10-100 m/s and signal amplitude typical for audible speech have been developed. The enhancing of the mitigation of solitary and shock waves in 1-D chains were demonstrated and a new protective medium was designed for practical applications. 1-D, 2-D and 3-D strongly nonlinear system have been investigated providing a broad impact on the whole area of strongly nonlinear wave dynamics and creating experimental basis for new

  20. Automation and schema acquisition in learning elementary computer programming : implications for the design of practice

    NARCIS (Netherlands)

    van Merrienboer, Jeroen J.G.; van Merrienboer, J.J.G.; Paas, Fred G.W.C.

    1990-01-01

    Two complementary processes may be distinguished in learning a complex cognitive skill such as computer programming. First, automation offers task-specific procedures that may directly control programming behavior, second, schema acquisition offers cognitive structures that provide analogies in new

  1. Simulation-based Design and Validation of Automated Contingency Management for Propulsion Systems

    Data.gov (United States)

    National Aeronautics and Space Administration — This paper introduces a novel Prognostics-enhanced Automated Contingency Management (or ACM+P) paradigm based on both current health state (diagnosis) and future...

  2. Lead User Design: Medication Management in Electronic Medical Records.

    Science.gov (United States)

    Price, Morgan; Weber, Jens H; Davies, Iryna; Bellwood, Paule

    2015-01-01

    Improvements in medication management may lead to a reduction of preventable errors. Usability and user experience issues are common and related to achieving benefits of Electronic Medical Records (EMRs). This paper reports on a novel study that combines the lead user method with a safety engineering review to discover an innovative design for the medication management module in EMRs in primary care. Eight lead users were recruited that represented prescribers and clinical pharmacists with expertise in EMR design, evidence-based medicine, medication safety and medication research. Eight separate medication management module designs were prototyped and validated, one with each lead user. A parallel safety review of medicaiton management was completed. The findings were synthesized into a single common set of goals, activities and one interactive, visual prototype. The lead user method with safety review proved to be an effective way to elicit diverse user goals and synthesize them into a common design. The resulting design ideas focus on meeting the goals of quality, efficiency, safety, reducing the cognitive load on the user, and improving communication wih the patient and the care team. Design ideas are being adapted to an existing EMR product, providing areas for further work.

  3. Designing for flexible interaction between humans and automation: delegation interfaces for supervisory control.

    Science.gov (United States)

    Miller, Christopher A; Parasuraman, Raja

    2007-02-01

    To develop a method enabling human-like, flexible supervisory control via delegation to automation. Real-time supervisory relationships with automation are rarely as flexible as human task delegation to other humans. Flexibility in human-adaptable automation can provide important benefits, including improved situation awareness, more accurate automation usage, more balanced mental workload, increased user acceptance, and improved overall performance. We review problems with static and adaptive (as opposed to "adaptable") automation; contrast these approaches with human-human task delegation, which can mitigate many of the problems; and revise the concept of a "level of automation" as a pattern of task-based roles and authorizations. We argue that delegation requires a shared hierarchical task model between supervisor and subordinates, used to delegate tasks at various levels, and offer instruction on performing them. A prototype implementation called Playbook is described. On the basis of these analyses, we propose methods for supporting human-machine delegation interactions that parallel human-human delegation in important respects. We develop an architecture for machine-based delegation systems based on the metaphor of a sports team's "playbook." Finally, we describe a prototype implementation of this architecture, with an accompanying user interface and usage scenario, for mission planning for uninhabited air vehicles. Delegation offers a viable method for flexible, multilevel human-automation interaction to enhance system performance while maintaining user workload at a manageable level. Most applications of adaptive automation (aviation, air traffic control, robotics, process control, etc.) are potential avenues for the adaptable, delegation approach we advocate. We present an extended example for uninhabited air vehicle mission planning.

  4. Penetrógrafo eletrônico automático Automatic electronic recording penetrometer

    Directory of Open Access Journals (Sweden)

    Aloísio Bianchini

    2002-01-01

    Full Text Available O presente trabalho relata o desenvolvimento de um penetrógrafo, construído para operar de forma automática, executando um ensaio de penetração com um simples toque no botão de partida. Ele possui incorporado, um sistema dedicado de aquisição de dados, que pode armazenar até 187 ensaios e uma interface de comunicação, dispensando a conexão ao microcomputador ou "datalogger". As condições do ensaio como, por exemplo, data, localização (latitude e longitude e profundidade, podem ser atualizadas, assim como a aferição da célula de carga, via teclado com mostrador de duas linhas. Verificou-se variação de velocidade This paper presents the development of an automatic recording penetrometer, which operates at the touch of a button. It incorporates a data acquisition system, which can store data of 187 tests and has a serial PC interface. The test characterization such as dates, location (latitude and longitude can be recorded as well. The maximum working depth may be set and the load cell calibration can be verified through a keyboard with 2 lines display. A speed variation error of < 5% compared to ASAE standard was verified for cone indices between 500 and 5,684 kPa. The equipment is compact, easy to handle and can realize one test every minute.

  5. Automated Methods to Extract Patient New Information from Clinical Notes in Electronic Health Record Systems

    Science.gov (United States)

    Zhang, Rui

    2013-01-01

    The widespread adoption of Electronic Health Record (EHR) has resulted in rapid text proliferation within clinical care. Clinicians' use of copying and pasting functions in EHR systems further compounds this by creating a large amount of redundant clinical information in clinical documents. A mixture of redundant information (especially outdated…

  6. Design and experimental tests of free electron laser wire scanners

    Directory of Open Access Journals (Sweden)

    G. L. Orlandi

    2016-09-01

    Full Text Available SwissFEL is a x-rays free electron laser (FEL driven by a 5.8 GeV linac under construction at Paul Scherrer Institut. In SwissFEL, wire scanners (WSCs will be complementary to view-screens for emittance measurements and routinely used to monitor the transverse profile of the electron beam during FEL operations. The SwissFEL WSC is composed of an in-vacuum beam-probe—motorized by a stepper motor—and an out-vacuum pick-up of the wire signal. The mechanical stability of the WSC in-vacuum hardware has been characterized on a test bench. In particular, the motor induced vibrations of the wire have been measured and mapped for different motor speeds. Electron-beam tests of the entire WSC setup together with different wire materials have been carried out at the 250 MeV SwissFEL Injector Test Facility (SITF, Paul Scherrer Institut, CH and at FERMI (Elettra-Sincrotrone Trieste, Italy. In particular, a comparative study of the relative measurement accuracy and the radiation-dose release of Al(99∶Si(1 and tungsten (W wires has been carried out. On the basis of the outcome of the bench and electron-beam tests, the SwissFEL WSC can be qualified as a high resolution and machine-saving diagnostic tool in consideration of the mechanical stability of the scanning wire at the micrometer level and the choice of the wire material ensuring a drastic reduction of the radiation-dose release with respect to conventional metallic wires. The main aspects of the design, laboratory characterization and electron beam tests of the SwissFEL WSCs are presented.

  7. Multiple pulse electron beam converter design for high power radiography

    Science.gov (United States)

    Pincosy, P. A.; Back, N.; Bergstrom, P. M.; Chen, Yu-Jiuan; Poulsen, P.

    2001-06-01

    The typical response of the x-ray converter material to the passage of a high-powered relativistic electron beam is vaporization and rapid dispersal. The effect of this dispersal on subsequent pulses for multi-pulse radiography is the collective effects on the propagation of the electron beam through the expanding plasma and the reduced number of electron to photon interactions. Thus, for the dual-axis radiographic hydrodynamic test facility, the converter material must either be replaced or confined long enough to accommodate the entire pulse train. Typically the 1-mm-thick high Z and full density converter material is chosen to give peak dose and minimum radiographic spot. For repeated pulses we propose a modified converter, constructed of either low density, high Z material in the form of foam or of foils spaced over ten times the axial thickness of the standard 1 mm converter. The converter material is confined within a tube to impede outward motion in radius outside the beam interaction region. We report single-pulse experiments which measure the dose and spot size produced by the modified converter and compare them to similar measurements made by the standard converter. For multiple pulses over a microsecond time scale, we calculate the radial and axial hydrodynamic flow to study the material reflux into the converter volume and the resultant density decrease as the electron beam energy is deposited. Both the electron transport through the expanding low density plasma and beam in the higher density material are modeled. The x-ray source dose and spot size are calculated to evaluate the impact of the changing converter material density distribution on the radiographic spot size and dose. The results indicate that a multiple-pulse converter design for three or four high-power beam pulses is feasible.

  8. Design and experimental tests of free electron laser wire scanners

    Science.gov (United States)

    Orlandi, G. L.; Heimgartner, P.; Ischebeck, R.; Loch, C. Ozkan; Trovati, S.; Valitutti, P.; Schlott, V.; Ferianis, M.; Penco, G.

    2016-09-01

    SwissFEL is a x-rays free electron laser (FEL) driven by a 5.8 GeV linac under construction at Paul Scherrer Institut. In SwissFEL, wire scanners (WSCs) will be complementary to view-screens for emittance measurements and routinely used to monitor the transverse profile of the electron beam during FEL operations. The SwissFEL WSC is composed of an in-vacuum beam-probe—motorized by a stepper motor—and an out-vacuum pick-up of the wire signal. The mechanical stability of the WSC in-vacuum hardware has been characterized on a test bench. In particular, the motor induced vibrations of the wire have been measured and mapped for different motor speeds. Electron-beam tests of the entire WSC setup together with different wire materials have been carried out at the 250 MeV SwissFEL Injector Test Facility (SITF, Paul Scherrer Institut, CH) and at FERMI (Elettra-Sincrotrone Trieste, Italy). In particular, a comparative study of the relative measurement accuracy and the radiation-dose release of Al (99 )∶Si (1 ) and tungsten (W) wires has been carried out. On the basis of the outcome of the bench and electron-beam tests, the SwissFEL WSC can be qualified as a high resolution and machine-saving diagnostic tool in consideration of the mechanical stability of the scanning wire at the micrometer level and the choice of the wire material ensuring a drastic reduction of the radiation-dose release with respect to conventional metallic wires. The main aspects of the design, laboratory characterization and electron beam tests of the SwissFEL WSCs are presented.

  9. Design and Achievement of User Interface Automation Testing of Linux Based on Element Tree of DogTail

    Directory of Open Access Journals (Sweden)

    Yuan Wen-Chao

    2017-01-01

    Full Text Available As Linux gets more popular around the world, the advantage of the open source on software makes people do automated UI test by unified testing framework. UI software testing can guarantee the rationality of User Interface of Linux and accuracy of the UI’s widgets. In order to set free from fuzzy and repeated manual testing, and improve efficiency, this paper achieves automation testing of UI under Linux, and proposes a method to identify and test UI widgets under Linux, which is according to element tree of DogTail automaton testing framework. It achieves automation test of UI under Linux. According to this method, Aiming at the product of Red Hat Subscription Manager under Red Hat Enterprise Linux, it designs the automation test plan of this series of product’s dialogs. After many tests, it is indicated that this plan can identify UI widgets accurately and rationally, describe the structure of software clearly, avoid software errors and improve efficiency of the software. Simultaneously, it also can be used in the internationalization testing for checking translation during software internationalization.

  10. Overview of software products for the terrain analysis in the tasks of design automation of wind-power stations

    OpenAIRE

    Volkov Andrey Anatol’evich; Sukneva Luiza Valer'evna; Kirschke Heiko

    2014-01-01

    The lack of ground and constantly growing price for energy sources are the reason for using alternative energy. The rules of the world community for environmental protection is the motivation for using renewable energy sources. It is necessary to automate the processes of the design technology for the alternative energy structures and their operation, as well as data gathering and analisys on all the existing objects. There is also the need to automise these objects' management. The topic of ...

  11. A Closed-Loop Proportional-Integral (PI) Control Software for Fully Mechanically Controlled Automated Electron Microscopic Tomography

    Energy Technology Data Exchange (ETDEWEB)

    2016-06-23

    A closed-loop proportional-integral (PI) control software is provided for fully mechanically controlled automated electron microscopic tomography. The software is developed based on Gatan DigitalMicrograph, and is compatible with Zeiss LIBRA 120 transmission electron microscope. However, it can be expanded to other TEM instrument with modification. The software consists of a graphical user interface, a digital PI controller, an image analyzing unit, and other drive units (i.e.: image acquire unit and goniometer drive unit). During a tomography data collection process, the image analyzing unit analyzes both the accumulated shift and defocus value of the latest acquired image, and provides the results to the digital PI controller. The digital PI control compares the results with the preset values and determines the optimum adjustments of the goniometer. The goniometer drive unit adjusts the spatial position of the specimen according to the instructions given by the digital PI controller for the next tilt angle and image acquisition. The goniometer drive unit achieves high precision positioning by using a backlash elimination method. The major benefits of the software are: 1) the goniometer drive unit keeps pre-aligned/optimized beam conditions unchanged and achieves position tracking solely through mechanical control; 2) the image analyzing unit relies on only historical data and therefore does not require additional images/exposures; 3) the PI controller enables the system to dynamically track the imaging target with extremely low system error.

  12. Design Requirements for High-Efficiency Electronic Ballasts

    Science.gov (United States)

    Takahashi, Yuuji; Shimizu, Keiichi

    The energy loss of an electronic ballast is mainly composed of switch loss and induction loss. The loss decreases when setting the component values so as to reduce the phase angle of the road circuit. However, the lamp current limiting action falls and fails to stably operate the lamp. We have examined the ways to improve the control stability by using the loop transfer function, the bode plot in particular. By designing a control circuit with the experimentally measured loop transfer function and the transfer function of each functional circuit block, the tested lamp was able to operate stably.

  13. Application of FPGA's in Flexible Analogue Electronic Image Generator Design

    Directory of Open Access Journals (Sweden)

    Peter Kulla

    2006-01-01

    Full Text Available This paper focuses on usage of the FPGAs (Field Programmable Gate Arrays Xilinx as a part of our more complex workdedicated to design of flexible analogue electronic images generator for application in TV measurement technique or/and TV servicetechnique or/and education process. The FPGAs performs here the role of component colour R, G, B, synchronization and blanking signals source. These signals are next processed and amplified in other parts of the generator as NTSC/PAL source encoder and RF modulator. The main aim of this paper is to show the possibilities how with suitable development software use a FPGAs in analog TV technology.

  14. A new numerical technique to design satellite energetic electron detectors

    CERN Document Server

    Tuszewski, M G; Ingraham, J C

    2002-01-01

    Energetic charged particles trapped in the magnetosphere are routinely detected by satellite instruments. However, it is generally difficult to extract quantitative energy and angular information from such measurements because the interaction of energetic electrons with matter is rather complex. Beam calibrations and Monte-Carlo (MC) simulations are often used to evaluate a flight instrument once it is built. However, rules of thumb and past experience are common tools to design the instrument in the first place. Hence, we have developed a simple numerical procedure, based on analytical probabilities, suitable for instrumental design and evaluation. In addition to the geometrical response, the contributions of surface backscattering, edge penetration, and bremsstrahlung radiation are estimated. The new results are benchmarked against MC calculations for a simple test case. Complicated effects, such as the contribution of the satellite to the instrumental response, can be estimated with the new formalism.

  15. Three Experiments Examining the Use of Electroencephalogram,Event-Related Potentials, and Heart-Rate Variability for Real-Time Human-Centered Adaptive Automation Design

    Science.gov (United States)

    Prinzel, Lawrence J., III; Parasuraman, Raja; Freeman, Frederick G.; Scerbo, Mark W.; Mikulka, Peter J.; Pope, Alan T.

    2003-01-01

    Adaptive automation represents an advanced form of human-centered automation design. The approach to automation provides for real-time and model-based assessments of human-automation interaction, determines whether the human has entered into a hazardous state of awareness and then modulates the task environment to keep the operator in-the-loop , while maintaining an optimal state of task engagement and mental alertness. Because adaptive automation has not matured, numerous challenges remain, including what the criteria are, for determining when adaptive aiding and adaptive function allocation should take place. Human factors experts in the area have suggested a number of measures including the use of psychophysiology. This NASA Technical Paper reports on three experiments that examined the psychophysiological measures of event-related potentials, electroencephalogram, and heart-rate variability for real-time adaptive automation. The results of the experiments confirm the efficacy of these measures for use in both a developmental and operational role for adaptive automation design. The implications of these results and future directions for psychophysiology and human-centered automation design are discussed.

  16. Ultraviolet Free Electron Laser Facility preliminary design report

    Energy Technology Data Exchange (ETDEWEB)

    Ben-Zvi, I. [ed.

    1993-02-01

    This document, the Preliminary Design Report (PDR) for the Brookhaven Ultraviolet Free Electron Laser (UV FEL) facility, describes all the elements of a facility proposed to meet the needs of a research community which requires ultraviolet sources not currently available as laboratory based lasers. Further, for these experiments, the requisite properties are not extant in either the existing second or upcoming third generation synchrotron light sources. This document is the result of our effort at BNL to identify potential users, determine the requirements of their experiments, and to design a facility which can not only satisfy the existing need, but have adequate flexibility for possible future extensions as need dictates and as evolving technology allows. The PDR is comprised of three volumes. In this, the first volume, background for the development of the proposal is given, including descriptions of the UV FEL facility, and representative examples of the science it was designed to perform. Discussion of the limitations and potential directions for growth are also included. A detailed description of the facility design is then provided, which addresses the accelerator, optical, and experimental systems. Information regarding the conventional construction for the facility is contained in an addendum to volume one (IA).

  17. Advanced Air Traffic Management Research (Human Factors and Automation): NASA Research Initiatives in Human-Centered Automation Design in Airspace Management

    Science.gov (United States)

    Corker, Kevin M.; Condon, Gregory W. (Technical Monitor)

    1996-01-01

    NASA has initiated a significant thrust of research and development focused on providing the flight crew and air traffic managers automation aids to increase capacity in en route and terminal area operations through the use of flexible, more fuel-efficient routing, while improving the level of safety in commercial carrier operations. In that system development, definition of cognitive requirements for integrated multi-operator dynamic aiding systems is fundamental. The core processes of control and the distribution of decision making in that control are undergoing extensive analysis. From our perspective, the human operators and the procedures by which they interact are the fundamental determinants of the safe, efficient, and flexible operation of the system. In that perspective, we have begun to explore what our experience has taught will be the most challenging aspects of designing and integrating human-centered automation in the advanced system. We have performed a full mission simulation looking at the role shift to self-separation on board the aircraft with the rules of the air guiding behavior and the provision of a cockpit display of traffic information and an on-board traffic alert system that seamlessly integrates into the TCAS operations. We have performed and initial investigation of the operational impact of "Dynamic Density" metrics on controller relinquishing and reestablishing full separation authority. (We follow the assumption that responsibility at all times resides with the controller.) This presentation will describe those efforts as well as describe the process by which we will guide the development of error tolerant systems that are sensitive to shifts in operator work load levels and dynamic shifts in the operating point of air traffic management.

  18. Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis

    Directory of Open Access Journals (Sweden)

    Neil Vasdev

    2016-08-01

    Full Text Available Column-switching high performance liquid chromatography (HPLC is extensively used for the critical analysis of radiolabeled ligands and their metabolites in plasma. However, the lack of streamlined apparatus and consequently varying protocols remain as a challenge among positron emission tomography laboratories. We report here the prototype apparatus and implementation of a fully automated and simplified column-switching procedure to allow for the easy and automated determination of radioligands and their metabolites in up to 5 mL of plasma. The system has been used with conventional UV and coincidence radiation detectors, as well as with a single quadrupole mass spectrometer.

  19. Design and Prototype of an Automated Column-Switching HPLC System for Radiometabolite Analysis.

    Science.gov (United States)

    Vasdev, Neil; Collier, Thomas Lee

    2016-08-17

    Column-switching high performance liquid chromatography (HPLC) is extensively used for the critical analysis of radiolabeled ligands and their metabolites in plasma. However, the lack of streamlined apparatus and consequently varying protocols remain as a challenge among positron emission tomography laboratories. We report here the prototype apparatus and implementation of a fully automated and simplified column-switching procedure to allow for the easy and automated determination of radioligands and their metabolites in up to 5 mL of plasma. The system has been used with conventional UV and coincidence radiation detectors, as well as with a single quadrupole mass spectrometer.

  20. Search Hanford accessible reports electronically system design description. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Gilomen, T.L.

    1995-12-31

    The Search Hanford Accessible Records Electronically (SHARE) system was produced by a combined team of personnel from Westinghouse Hanford Company (WHC) Corrective Action Data Systems (CADS) and Information Resource Management (IRM) Information and Scientific Systems (ISS) organizations. The ESQD Text Evaluation and exchange Tool (ETEXT) prototype was used as a basis for the requirements used to support this design/build effort. TOPIC was used to build the SHARE application. TOPIC is a text search and retrieval software product produced by the Verity Corporation. The TOPIC source code is not provided with the product, and the programs cannot be changed. TOPIC can be customized for special requirements. The software is fully documented. Help messages, menu and screen layouts, command edits and options, and internal system design are all described in the TOPIC documentation. This System Design Description (SDD) will not reiterate the TOPIC documentation and design. Instead, it will focus on the SHARE installation of TOPIC. This SDD is designed to assist the SHARE database/infobase administrator (DBA) in maintaining and supporting the application. It assumes that the assigned DBA is knowledgeable in using the TOPIC product, and is also knowledgeable in using a personal computer (PC), Disk Operating System (DOS) commands, and the document WHC-CM-3-10. SHARE is an Impact Level 4 system, and all activities related to SHARE must conform with the WHC-CM-3-10 procedures for an Impact Level 4 system. The Alternatives Analysis will be treated as a level 3-Q document, to allow for reference by potential future projects.

  1. Self-assembled three dimensional network designs for soft electronics

    Science.gov (United States)

    Jang, Kyung-In; Li, Kan; Chung, Ha Uk; Xu, Sheng; Jung, Han Na; Yang, Yiyuan; Kwak, Jean Won; Jung, Han Hee; Song, Juwon; Yang, Ce; Wang, Ao; Liu, Zhuangjian; Lee, Jong Yoon; Kim, Bong Hoon; Kim, Jae-Hwan; Lee, Jungyup; Yu, Yongjoon; Kim, Bum Jun; Jang, Hokyung; Yu, Ki Jun; Kim, Jeonghyun; Lee, Jung Woo; Jeong, Jae-Woong; Song, Young Min; Huang, Yonggang; Zhang, Yihui; Rogers, John A.

    2017-06-01

    Low modulus, compliant systems of sensors, circuits and radios designed to intimately interface with the soft tissues of the human body are of growing interest, due to their emerging applications in continuous, clinical-quality health monitors and advanced, bioelectronic therapeutics. Although recent research establishes various materials and mechanics concepts for such technologies, all existing approaches involve simple, two-dimensional (2D) layouts in the constituent micro-components and interconnects. Here we introduce concepts in three-dimensional (3D) architectures that bypass important engineering constraints and performance limitations set by traditional, 2D designs. Specifically, open-mesh, 3D interconnect networks of helical microcoils formed by deterministic compressive buckling establish the basis for systems that can offer exceptional low modulus, elastic mechanics, in compact geometries, with active components and sophisticated levels of functionality. Coupled mechanical and electrical design approaches enable layout optimization, assembly processes and encapsulation schemes to yield 3D configurations that satisfy requirements in demanding, complex systems, such as wireless, skin-compatible electronic sensors.

  2. Self-assembled three dimensional network designs for soft electronics

    Science.gov (United States)

    Jang, Kyung-In; Li, Kan; Chung, Ha Uk; Xu, Sheng; Jung, Han Na; Yang, Yiyuan; Kwak, Jean Won; Jung, Han Hee; Song, Juwon; Yang, Ce; Wang, Ao; Liu, Zhuangjian; Lee, Jong Yoon; Kim, Bong Hoon; Kim, Jae-Hwan; Lee, Jungyup; Yu, Yongjoon; Kim, Bum Jun; Jang, Hokyung; Yu, Ki Jun; Kim, Jeonghyun; Lee, Jung Woo; Jeong, Jae-Woong; Song, Young Min; Huang, Yonggang; Zhang, Yihui; Rogers, John A.

    2017-01-01

    Low modulus, compliant systems of sensors, circuits and radios designed to intimately interface with the soft tissues of the human body are of growing interest, due to their emerging applications in continuous, clinical-quality health monitors and advanced, bioelectronic therapeutics. Although recent research establishes various materials and mechanics concepts for such technologies, all existing approaches involve simple, two-dimensional (2D) layouts in the constituent micro-components and interconnects. Here we introduce concepts in three-dimensional (3D) architectures that bypass important engineering constraints and performance limitations set by traditional, 2D designs. Specifically, open-mesh, 3D interconnect networks of helical microcoils formed by deterministic compressive buckling establish the basis for systems that can offer exceptional low modulus, elastic mechanics, in compact geometries, with active components and sophisticated levels of functionality. Coupled mechanical and electrical design approaches enable layout optimization, assembly processes and encapsulation schemes to yield 3D configurations that satisfy requirements in demanding, complex systems, such as wireless, skin-compatible electronic sensors. PMID:28635956

  3. Self-assembled three dimensional network designs for soft electronics.

    Science.gov (United States)

    Jang, Kyung-In; Li, Kan; Chung, Ha Uk; Xu, Sheng; Jung, Han Na; Yang, Yiyuan; Kwak, Jean Won; Jung, Han Hee; Song, Juwon; Yang, Ce; Wang, Ao; Liu, Zhuangjian; Lee, Jong Yoon; Kim, Bong Hoon; Kim, Jae-Hwan; Lee, Jungyup; Yu, Yongjoon; Kim, Bum Jun; Jang, Hokyung; Yu, Ki Jun; Kim, Jeonghyun; Lee, Jung Woo; Jeong, Jae-Woong; Song, Young Min; Huang, Yonggang; Zhang, Yihui; Rogers, John A

    2017-06-21

    Low modulus, compliant systems of sensors, circuits and radios designed to intimately interface with the soft tissues of the human body are of growing interest, due to their emerging applications in continuous, clinical-quality health monitors and advanced, bioelectronic therapeutics. Although recent research establishes various materials and mechanics concepts for such technologies, all existing approaches involve simple, two-dimensional (2D) layouts in the constituent micro-components and interconnects. Here we introduce concepts in three-dimensional (3D) architectures that bypass important engineering constraints and performance limitations set by traditional, 2D designs. Specifically, open-mesh, 3D interconnect networks of helical microcoils formed by deterministic compressive buckling establish the basis for systems that can offer exceptional low modulus, elastic mechanics, in compact geometries, with active components and sophisticated levels of functionality. Coupled mechanical and electrical design approaches enable layout optimization, assembly processes and encapsulation schemes to yield 3D configurations that satisfy requirements in demanding, complex systems, such as wireless, skin-compatible electronic sensors.

  4. Data Mining Approaches for Modeling Complex Electronic Circuit Design Activities

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Yongjin [Ajou University, Suwon, South Korea; Omitaomu, Olufemi A [ORNL; Wang, Gi-Nam [Ajou University, Suwon, South Korea

    2008-01-01

    A printed circuit board (PCB) is an essential part of modern electronic circuits. It is made of a flat panel of insulating materials with patterned copper foils that act as electric pathways for various components such as ICs, diodes, capacitors, resistors, and coils. The size of PCBs has been shrinking over the years, while the number of components mounted on these boards has increased considerably. This trend makes the design and fabrication of PCBs ever more difficult. At the beginning of design cycles, it is important to estimate the time to complete the steps required accurately, based on many factors such as the required parts, approximate board size and shape, and a rough sketch of schematics. Current approach uses multiple linear regression (MLR) technique for time and cost estimations. However, the need for accurate predictive models continues to grow as the technology becomes more advanced. In this paper, we analyze a large volume of historical PCB design data, extract some important variables, and develop predictive models based on the extracted variables using a data mining approach. The data mining approach uses an adaptive support vector regression (ASVR) technique; the benchmark model used is the MLR technique currently being used in the industry. The strengths of SVR for this data include its ability to represent data in high-dimensional space through kernel functions. The computational results show that a data mining approach is a better prediction technique for this data. Our approach reduces computation time and enhances the practical applications of the SVR technique.

  5. Value sensitive design of automated workload distribution support for traffic control teams

    NARCIS (Netherlands)

    Harbers, M.; Neerincx, M.A.

    2014-01-01

    This paper studies the effects of automated support for workload distribution in traffic control teams on human values such as security, autonomy and privacy. The paper describes a workshop in which the support system's stakeholders, their values, and the effects of the support system on these

  6. Psi4 1.1: An Open-Source Electronic Structure Program Emphasizing Automation, Advanced Libraries, and Interoperability.

    Science.gov (United States)

    Parrish, Robert M; Burns, Lori A; Smith, Daniel G A; Simmonett, Andrew C; DePrince, A Eugene; Hohenstein, Edward G; Bozkaya, Uğur; Sokolov, Alexander Yu; Di Remigio, Roberto; Richard, Ryan M; Gonthier, Jérôme F; James, Andrew M; McAlexander, Harley R; Kumar, Ashutosh; Saitow, Masaaki; Wang, Xiao; Pritchard, Benjamin P; Verma, Prakash; Schaefer, Henry F; Patkowski, Konrad; King, Rollin A; Valeev, Edward F; Evangelista, Francesco A; Turney, Justin M; Crawford, T Daniel; Sherrill, C David

    2017-07-11

    Psi4 is an ab initio electronic structure program providing methods such as Hartree-Fock, density functional theory, configuration interaction, and coupled-cluster theory. The 1.1 release represents a major update meant to automate complex tasks, such as geometry optimization using complete-basis-set extrapolation or focal-point methods. Conversion of the top-level code to a Python module means that Psi4 can now be used in complex workflows alongside other Python tools. Several new features have been added with the aid of libraries providing easy access to techniques such as density fitting, Cholesky decomposition, and Laplace denominators. The build system has been completely rewritten to simplify interoperability with independent, reusable software components for quantum chemistry. Finally, a wide range of new theoretical methods and analyses have been added to the code base, including functional-group and open-shell symmetry adapted perturbation theory, density-fitted coupled cluster with frozen natural orbitals, orbital-optimized perturbation and coupled-cluster methods (e.g., OO-MP2 and OO-LCCD), density-fitted multiconfigurational self-consistent field, density cumulant functional theory, algebraic-diagrammatic construction excited states, improvements to the geometry optimizer, and the "X2C" approach to relativistic corrections, among many other improvements.

  7. Automated transmission-mode scanning electron microscopy (tSEM) for large volume analysis at nanoscale resolution.

    Science.gov (United States)

    Kuwajima, Masaaki; Mendenhall, John M; Lindsey, Laurence F; Harris, Kristen M

    2013-01-01

    Transmission-mode scanning electron microscopy (tSEM) on a field emission SEM platform was developed for efficient and cost-effective imaging of circuit-scale volumes from brain at nanoscale resolution. Image area was maximized while optimizing the resolution and dynamic range necessary for discriminating key subcellular structures, such as small axonal, dendritic and glial processes, synapses, smooth endoplasmic reticulum, vesicles, microtubules, polyribosomes, and endosomes which are critical for neuronal function. Individual image fields from the tSEM system were up to 4,295 µm(2) (65.54 µm per side) at 2 nm pixel size, contrasting with image fields from a modern transmission electron microscope (TEM) system, which were only 66.59 µm(2) (8.160 µm per side) at the same pixel size. The tSEM produced outstanding images and had reduced distortion and drift relative to TEM. Automated stage and scan control in tSEM easily provided unattended serial section imaging and montaging. Lens and scan properties on both TEM and SEM platforms revealed no significant nonlinear distortions within a central field of ∼100 µm(2) and produced near-perfect image registration across serial sections using the computational elastic alignment tool in Fiji/TrakEM2 software, and reliable geometric measurements from RECONSTRUCT™ or Fiji/TrakEM2 software. Axial resolution limits the analysis of small structures contained within a section (∼45 nm). Since this new tSEM is non-destructive, objects within a section can be explored at finer axial resolution in TEM tomography with current methods. Future development of tSEM tomography promises thinner axial resolution producing nearly isotropic voxels and should provide within-section analyses of structures without changing platforms. Brain was the test system given our interest in synaptic connectivity and plasticity; however, the new tSEM system is readily applicable to other biological systems.

  8. Automated transmission-mode scanning electron microscopy (tSEM for large volume analysis at nanoscale resolution.

    Directory of Open Access Journals (Sweden)

    Masaaki Kuwajima

    Full Text Available Transmission-mode scanning electron microscopy (tSEM on a field emission SEM platform was developed for efficient and cost-effective imaging of circuit-scale volumes from brain at nanoscale resolution. Image area was maximized while optimizing the resolution and dynamic range necessary for discriminating key subcellular structures, such as small axonal, dendritic and glial processes, synapses, smooth endoplasmic reticulum, vesicles, microtubules, polyribosomes, and endosomes which are critical for neuronal function. Individual image fields from the tSEM system were up to 4,295 µm(2 (65.54 µm per side at 2 nm pixel size, contrasting with image fields from a modern transmission electron microscope (TEM system, which were only 66.59 µm(2 (8.160 µm per side at the same pixel size. The tSEM produced outstanding images and had reduced distortion and drift relative to TEM. Automated stage and scan control in tSEM easily provided unattended serial section imaging and montaging. Lens and scan properties on both TEM and SEM platforms revealed no significant nonlinear distortions within a central field of ∼100 µm(2 and produced near-perfect image registration across serial sections using the computational elastic alignment tool in Fiji/TrakEM2 software, and reliable geometric measurements from RECONSTRUCT™ or Fiji/TrakEM2 software. Axial resolution limits the analysis of small structures contained within a section (∼45 nm. Since this new tSEM is non-destructive, objects within a section can be explored at finer axial resolution in TEM tomography with current methods. Future development of tSEM tomography promises thinner axial resolution producing nearly isotropic voxels and should provide within-section analyses of structures without changing platforms. Brain was the test system given our interest in synaptic connectivity and plasticity; however, the new tSEM system is readily applicable to other biological systems.

  9. Design and Implementation of an Electronic Identification Card

    Directory of Open Access Journals (Sweden)

    J. Flores‐Escalante

    2009-12-01

    Full Text Available In this paper we present an “Electronic Identification Card” (EIC. This EIC is designed to provide a high degree of security foruser authentication using biometrics, cryptography and steganography. The EIC encrypts the user's personal information as wellas his fingerprint and then embed it in a photograph of the user's face. Two factors of authentication are used in the process:“something the user knows” and “something the user has”, in order to provide layers of security to shield the card. The EIC givesthe flexibility to operate in database systems, storage media like chips for smart cards or digital passports. We also developedschemes to authenticate users through the EIC, like remote authentication by a Web interface and the authentication in a localmachine.

  10. EChO payload electronics architecture and SW design

    Science.gov (United States)

    Focardi, M.; Di Giorgio, A. M.; Farina, M.; Pancrazzi, M.; Ottensamer, R.; Lim, T. L.; Pezzuto, S.; Micela, G.; Pace, E.

    2015-12-01

    EChO is a three-modules (VNIR, SWIR, MWIR), highly integrated spectrometer, covering the wavelength range from 0.55 μ m to 11.0 μ m. The baseline design includes the goal wavelength extension to 0.4 μ m while an optional LWIR module extends the range to the goal wavelength of 16.0 μ m. An Instrument Control Unit (ICU) is foreseen as the main electronic subsystem interfacing the spacecraft and collecting data from all the payload spectrometers modules. ICU is in charge of two main tasks: the overall payload control ( Instrument Control Function) and the housekeepings and scientific data digital processing ( Data Processing Function), including the lossless compression prior to store the science data to the Solid State Mass Memory of the Spacecraft. These two main tasks are accomplished thanks to the Payload On Board Software (P-OBSW) running on the ICU CPUs.

  11. Electron microscopy by specimen design: application to strain measurements.

    Science.gov (United States)

    Cherkashin, Nikolay; Denneulin, Thibaud; Hÿtch, Martin J

    2017-09-29

    A bewildering number of techniques have been developed for transmission electron microscopy (TEM), involving the use of ever more complex combinations of lens configurations, apertures and detector geometries. In parallel, the developments in the field of ion beam instruments have modernized sample preparation and enabled the preparation of various types of materials. However, the desired final specimen geometry is always almost the same: a thin foil of uniform thickness. Here we will show that judicious design of specimen geometry can make all the difference and that experiments can be carried out on the most basic electron microscope and in the usual imaging modes. We propose two sample preparation methods that allow the formation of controlled moiré patterns for general monocrystalline structures in cross-section and at specific sites. We developed moiré image treatment algorithms using an absolute correction of projection lens distortions of a TEM that allows strain measurements and mapping with a nanometer resolution and 10-4 precision. Imaging and diffraction techniques in other fields may in turn benefit from this technique in perspective.

  12. Electronic commerce, automation and online banking in Nigeria: challenges and benefits

    Directory of Open Access Journals (Sweden)

    B. Sc., M. Sc. Stephen A. Ojeka

    2011-05-01

    Full Text Available Electronic banking has been around for some time in the form of automatic teller machines and telephone transactions. More recently, it has been metamorphosed by the Internet; a new look and delivery channel for banking services that benefits both customers and banks. The objective of this paper is to find out the correlation between the anticipated benefits/challenges and encountered benefits/challenges. This paper therefore empirically, adopted the use of survey research to explore in quantitative terms the various challenges and benefits e-business poses to Nigeria businesses, with particular reference to Banking and Finance Industry. It was found out that there is statistically significant difference between the anticipated and encountered benefits and major challenge is the security breach faced the customers. We therefore recommend that workshops should be organized for customers periodically on how to keep their data secret especially on how to combine numbers to form password and Constant training of employees both local and international on new development in online trading should be encouraged.

  13. Design of Pixellated CMOS Photon Detector for Secondary Electron Detection in the Scanning Electron Microscope

    Directory of Open Access Journals (Sweden)

    Joon Huang Chuah

    2011-01-01

    Full Text Available This paper presents a novel method of detecting secondary electrons generated in the scanning electron microscope (SEM. The method suggests that the photomultiplier tube (PMT, traditionally used in the Everhart-Thornley (ET detector, is to be replaced with a configurable multipixel solid-state photon detector offering the advantages of smaller dimension, lower supply voltage and power requirements, and potentially cheaper product cost. The design of the proposed detector has been implemented using a standard 0.35 μm CMOS technology with optical enhancement. This microchip comprises main circuit constituents of an array of photodiodes connecting to respective noise-optimised transimpedance amplifiers (TIAs, a selector-combiner (SC circuit, and a postamplifier (PA. The design possesses the capability of detecting photons with low input optical power in the range of 1 nW with 100 μm × 100 μm sized photodiodes and achieves a total amplification of 180 dBΩ at the output.

  14. Automated Classification Of Scanning Electron Microscope Particle Images Using Morphological Analysis

    Science.gov (United States)

    Lamarche, B. L.; Lewis, R. R.; Girvin, D. C.; McKinley, J. P.

    2008-12-01

    We are developing a software tool that can automatically classify anthropogenic and natural aerosol particulates using morphological analysis. Our method was developed using SEM (background and secondary electron) images of single particles. Particle silhouettes are detected and converted into polygons using Intel's OpenCV image processing library. Our analysis then proceeds independently for the two kinds of images. Analysis of secondary images concerns itself solely with the silhouette and seeks to quantify its shape and roughness. Traversing the polygon with spline interpolation, we uniformly sample k(s), the signed curvature of the silhouette's path as a function of distance along the perimeter s. k(s) is invariant under rotation and translation. The power spectrum of k(s) qualitatively shows both shape and roughness: more power at low frequencies indicates variation in shape; more power at higher frequencies indicates a rougher silhouette. We present a series of filters (low-, band-, and high-pass) which we convolve with k(s) to yield a set of parameters that characterize the shape and roughness numerically. Analysis of backscatter images focuses on the (visual) texture, which is the result of both composition and geometry. Using the silhouette as a boundary, we compute the variogram, a statistical measure of inter-pixel covariance as a function of distance. Variograms take on characteristic curves, which we fit with a heuristic, asymptotic function that uses a small set of parameters. The combination of silhouette and variogram fit parameters forms the basis of a multidimensional classification space whose dimensionality we may reduce by principal component analysis and whose region boundaries allow us to classify new particles. This analysis is performed without a priori knowledge of other physical, chemical, or climatic properties. The method will be adapted to multi-particulate images.

  15. Automated variance reduction technique for three-dimensional Monte Carlo coupled electron-photon-positron simulation using deterministic importance functions

    Science.gov (United States)

    Dionne, Benoit

    Three-dimensional Monte Carlo coupled electron-photon-positron transport calculations are often performed to determine characteristics such as energy or charge deposition in a wide range of systems exposed to radiation field such as electronic circuitry in a space-environment, tissues exposed to radiotherapy linear accelerator beams, or radiation detectors. Modeling these systems constitute a challenging problem for the available computational methods and resources because they can involve; (i) very large attenuation, (ii) large number of secondary particles due to the electron-photon-positron cascade, and (iii) large and highly forward-peaked scattering. This work presents a new automated variance reduction technique, referred to as ADEIS (Angular adjoint-Driven Electron-photon-positron Importance Sampling), that takes advantage of the capability of deterministic methods to rapidly provide approximate information about the complete phase-space in order to automatically evaluate variance reduction parameters. More specifically, this work focuses on the use of discrete ordinates importance functions to evaluate angular transport and collision biasing parameters, and use them through a modified implementation of the weight-window technique. The application of this new method to complex Monte Carlo simulations has resulted in speedups as high as five orders of magnitude. Due to numerical difficulties in obtaining physical importance functions devoid of numerical artifacts, a limited form of smoothing was implemented to complement a scheme for automatic discretization parameters selection. This scheme improves the robustness, efficiency and statistical reliability of the methodology by optimizing the accuracy of the importance functions with respect to the additional computational cost from generating and using these functions. It was shown that it is essential to bias different species of particles with their specific importance functions. In the case of electrons and

  16. FIJI Macro 3D ART VeSElecT: 3D Automated Reconstruction Tool for Vesicle Structures of Electron Tomograms.

    Directory of Open Access Journals (Sweden)

    Kristin Verena Kaltdorf

    2017-01-01

    Full Text Available Automatic image reconstruction is critical to cope with steadily increasing data from advanced microscopy. We describe here the Fiji macro 3D ART VeSElecT which we developed to study synaptic vesicles in electron tomograms. We apply this tool to quantify vesicle properties (i in embryonic Danio rerio 4 and 8 days past fertilization (dpf and (ii to compare Caenorhabditis elegans N2 neuromuscular junctions (NMJ wild-type and its septin mutant (unc-59(e261. We demonstrate development-specific and mutant-specific changes in synaptic vesicle pools in both models. We confirm the functionality of our macro by applying our 3D ART VeSElecT on zebrafish NMJ showing smaller vesicles in 8 dpf embryos then 4 dpf, which was validated by manual reconstruction of the vesicle pool. Furthermore, we analyze the impact of C. elegans septin mutant unc-59(e261 on vesicle pool formation and vesicle size. Automated vesicle registration and characterization was implemented in Fiji as two macros (registration and measurement. This flexible arrangement allows in particular reducing false positives by an optional manual revision step. Preprocessing and contrast enhancement work on image-stacks of 1nm/pixel in x and y direction. Semi-automated cell selection was integrated. 3D ART VeSElecT removes interfering components, detects vesicles by 3D segmentation and calculates vesicle volume and diameter (spherical approximation, inner/outer diameter. Results are collected in color using the RoiManager plugin including the possibility of manual removal of non-matching confounder vesicles. Detailed evaluation considered performance (detected vesicles and specificity (true vesicles as well as precision and recall. We furthermore show gain in segmentation and morphological filtering compared to learning based methods and a large time gain compared to manual segmentation. 3D ART VeSElecT shows small error rates and its speed gain can be up to 68 times faster in comparison to manual

  17. Design and development of an automated and non-contact sensing system for continuous monitoring of plant health and growth.

    Science.gov (United States)

    Kacira, M; Ling, P P

    2001-01-01

    An automated system was designed and built to continuously monitor plant health and growth in a controlled environment using a distributed system approach for operational control and data collection. The computer-controlled system consisted of a motorized turntable to present the plants to the stationary sensors and reduce microclimate variability among the plants. Major sensing capabilities of the system included machine vision, infrared thermometry, time domain reflectometry, and micro-lysimeters. The system also maintained precise growth-medium moisture levels through a computer-controlled drip irrigation system. The system was capable of collecting required data continuously to monitor and to evaluate the plant health and growth.

  18. An efficient approach to bioconversion kinetic model generation based on automated microscale experimentation integrated with model driven experimental design

    DEFF Research Database (Denmark)

    Chen, B. H.; Micheletti, M.; Baganz, F.

    2009-01-01

    design. It incorporates a model driven approach to the experimental design that minimises the number of experiments to be performed, while still generating accurate values of kinetic parameters. The approach has been illustrated with the transketolase mediated asymmetric synthesis of L......Reliable models of enzyme kinetics are required for the effective design of bioconversion processes. Kinetic expressions of the enzyme-catalysed reaction rate however, are frequently complex and establishing accurate values of kinetic parameters normally requires a large number of experiments....... These can be both time consuming and expensive when working with the types of non-natural chiral intermediates important in pharmaceutical syntheses. This paper presents ail automated microscale approach to the rapid and cost effective generation of reliable kinetic models useful for bioconversion process...

  19. Mission Design Evaluation Using Automated Planning for High Resolution Imaging of Dynamic Surface Processes from the ISS

    Science.gov (United States)

    Knight, Russell; Donnellan, Andrea; Green, Joseph J.

    2013-01-01

    A challenge for any proposed mission is to demonstrate convincingly that the proposed systems will in fact deliver the science promised. Funding agencies and mission design personnel are becoming ever more skeptical of the abstractions that form the basis of the current state of the practice with respect to approximating science return. To address this, we have been using automated planning and scheduling technology to provide actual coverage campaigns that provide better predictive performance with respect to science return for a given mission design and set of mission objectives given implementation uncertainties. Specifically, we have applied an adaptation of ASPEN and SPICE to the Eagle-Eye domain that demonstrates the performance of the mission design with respect to coverage of science imaging targets that address climate change and disaster response. Eagle-Eye is an Earth-imaging telescope that has been proposed to fly aboard the International Space Station (ISS).

  20. Randomized trial of automated, electronic monitoring to facilitate early detection of sepsis in the intensive care unit*.

    Science.gov (United States)

    Hooper, Michael H; Weavind, Lisa; Wheeler, Arthur P; Martin, Jason B; Gowda, Supriya Srinivasa; Semler, Matthew W; Hayes, Rachel M; Albert, Daniel W; Deane, Norment B; Nian, Hui; Mathe, Janos L; Nadas, Andras; Sztipanovits, Janos; Miller, Anne; Bernard, Gordon R; Rice, Todd W

    2012-07-01

    To determine whether automated identification with physician notification of the systemic inflammatory response syndrome in medical intensive care unit patients expedites early administration of new antibiotics or improvement of other patient outcomes in patients with sepsis. : A prospective randomized, controlled, single center study. Medical intensive care unit of an academic, tertiary care medical center. Four hundred forty-two consecutive patients admitted over a 4-month period who met modified systemic inflammatory response syndrome criteria in a medical intensive care unit. Patients were randomized to monitoring by an electronic "Listening Application" to detect modified (systemic inflammatory response syndrome) criteria vs. usual care. The listening application notified physicians in real time when modified systemic inflammatory response syndrome criteria were detected, but did not provide management recommendations. The median time to new antibiotics was similar between the intervention and usual care groups when comparing among all patients (6.0 hr vs. 6.1 hr, p = .95), patients with sepsis (5.3 hr vs. 5.1 hr; p = .90), patients on antibiotics at enrollment (5.2 hr vs. 7.0 hr, p = .27), or patients not on antibiotics at enrollment (5.2 hr vs. 5.1 hr, p = .85). The amount of fluid administered following detection of modified systemic inflammatory response syndrome criteria was similar between groups whether comparing all patients or only patients who were hypotensive at enrollment. Other clinical outcomes including intensive care unit length of stay, hospital length of stay, and mortality were not shown to be different between patients in the intervention and control groups. Realtime alerts of modified systemic inflammatory response syndrome criteria to physicians in one tertiary care medical intensive care unit were feasible and safe but did not influence measured therapeutic interventions for sepsis or significantly alter clinical outcomes.

  1. Design and Development of the SMAP Microwave Radiometer Electronics

    Science.gov (United States)

    Piepmeier, Jeffrey R.; Medeiros, James J.; Horgan, Kevin A.; Brambora, Clifford K.; Estep, Robert H.

    2014-01-01

    The SMAP microwave radiometer will measure land surface brightness temperature at L-band (1413 MHz) in the presence of radio frequency interference (RFI) for soil moisture remote sensing. The radiometer design was driven by the requirements to incorporate internal calibration, to operate synchronously with the SMAP radar, and to mitigate the deleterious effects of RFI. The system design includes a highly linear super-heterodyne microwave receiver with internal reference loads and noise sources for calibration and an innovative digital signal processor and detection system. The front-end comprises a coaxial cable-based feed network, with a pair of diplexers and a coupled noise source, and radiometer front-end (RFE) box. Internal calibration is provided by reference switches and a common noise source inside the RFE. The RF back-end (RBE) downconverts the 1413 MHz channel to an intermediate frequency (IF) of 120 MHz. The IF signals are then sampled and quantized by high-speed analog-to-digital converters in the radiometer digital electronics (RDE) box. The RBE local oscillator and RDE sampling clocks are phase-locked to a common reference to ensure coherency between the signals. The RDE performs additional filtering, sub-band channelization, cross-correlation for measuring third and fourth Stokes parameters, and detection and integration of the first four raw moments of the signals. These data are packetized and sent to the ground for calibration and further processing. Here we discuss the novel features of the radiometer hardware particularly those influenced by the need to mitigate RFI.

  2. EGUN: An electron optics and gun design program

    Energy Technology Data Exchange (ETDEWEB)

    Herrmannsfeldt, W.B.

    1988-10-01

    The name EGUN has become commonly associated with the program also known as the SLAC Electron Trajectory Program. This document is an updated version of SLAC-226, published in 1979. The program itself has had substantial upgrading since then, but only a few new features are of much concern to the user. Most of the improvements are internal and are intended to improve speed or accuracy. EGUN is designed to compute trajectories of charged particles in electrostatic and magnetostatic fields, including the effects of space charge and self-magnetic fields. Starting options include Child's Law conditions on cathodes of various shapes, as well as used specified initial conditions. Either rectangular or cylindrical symmetry may be used. In the new jargon, the program is a 2-1/2 dimension code meaning 2-D in all fields and 3-D in all particle motion. A Poisson's Equation Solver is used to find the electrostatic fields by using difference equations derived from the boundary conditions. Magnetic fields are to be specified externally, by the user, by using one of several methods including data from another program or arbitrary configurations of coils. This edition of the documentation also covers the program EGN87c, which is a recently developed version of EGUN designed to be used on the newer models of personal computers, small main frames, work stations, etc. The EGN87c program uses the programming language C which is very transportable so the program should operate on any system that supports C. Plotting routines for most common PC monitors are included, and the capability to make hard copy plots on dot-matrix printer-plotters is provided. 18 refs., 7 figs.

  3. Design and implementation of the ATLAS TRT front end electronics

    Science.gov (United States)

    Newcomer, Mitch; Atlas TRT Collaboration

    2006-07-01

    The ATLAS TRT subsystem is comprised of 380,000 4 mm straw tube sensors ranging in length from 30 to 80 cm. Polypropelene plastic layers between straws and a xenon-based gas mixture in the straws allow the straws to be used for both tracking and transition radiation detection. Detector-mounted electronics with data sparsification was chosen to minimize the cable plant inside the super-conducting solenoid of the ATLAS inner tracker. The "on detector" environment required a small footprint, low noise, low power and radiation-tolerant readout capable of triggering at rates up to 20 MHz with an analog signal dynamic range of >300 times the discriminator setting. For tracking, a position resolution better than 150 μm requires leading edge trigger timing with ˜1 ns precision and for transition radiation detection, a charge collection time long enough to integrate the direct and reflected signal from the unterminated straw tube is needed for position-independent energy measurement. These goals have been achieved employing two custom Application-specific integrated circuits (ASICS) and board design techniques that successfully separate analog and digital functionality while providing an integral part of the straw tube shielding.

  4. Compact design for two-dimensional electronic spectroscopy

    Science.gov (United States)

    Huang, Zheng; Wang, Peng; Shen, Xiong; Yan, Tian-Min; Zhang, Yizhu; Liu, Jun

    2016-03-01

    We present a passively phase-stabilized two-dimensional electronic spectroscopy (2DES) with a compact size, and the ease of implementation and maintenance. Our design relies on a mask beam-splitter with four holes to form non-collinear box geometry, and a homebuilt stacked retroreflector, which introduces the phase-locked pulse sequence, remedying the instability of commonly used translation stages. The minimized size of the setup suppresses the influences of optical path-length fluctuations during measurements, improving the phase stability and precise timing of pulse sequences. In our 2DES, only few conventional optical components are used, which make this sophisticated instrumentation convenient to establish and particularly easy to conduct alignment. In data analysis, the self-referencing spectral interferometry (SRSI) method is first introduced to extract the complex-valued signal from spectral interferometry in 2DES. The alternative algorithm achieves the improvement of the signal-to-noise ratio (SNR) and considerable reduction of data acquisition time. The new setup is suitable over a tunable range of spectroscopic wavelength, from ultraviolet (UV) to the near-infrared (NIR) regime, and for ultra-broadband bandwidth, few-cycle laser pulses.

  5. Design, construction, and testing of an automated NIR in-line analysis system for potatoes. Part II. Development and testing of the automated semi-industrial system iith In-line NIR for the characterization of potatoes

    NARCIS (Netherlands)

    Brunt, K.; Smits, B.; Holthuis, H.

    2010-01-01

    An automated semi-industrial system with in-line near-infrared reflectance (NIR) for the characterization of the chemical composition of potatoes was designed and constructed, and its performance was tested. The system consisted of the following subsystems: sample crate manipulator, weighing unit

  6. Failure mode and effect analysis oriented to risk-reduction interventions in intraoperative electron radiation therapy: the specific impact of patient transportation, automation, and treatment planning availability.

    Science.gov (United States)

    López-Tarjuelo, Juan; Bouché-Babiloni, Ana; Santos-Serra, Agustín; Morillo-Macías, Virginia; Calvo, Felipe A; Kubyshin, Yuri; Ferrer-Albiach, Carlos

    2014-11-01

    Industrial companies use failure mode and effect analysis (FMEA) to improve quality. Our objective was to describe an FMEA and subsequent interventions for an automated intraoperative electron radiotherapy (IOERT) procedure with computed tomography simulation, pre-planning, and a fixed conventional linear accelerator. A process map, an FMEA, and a fault tree analysis are reported. The equipment considered was the radiance treatment planning system (TPS), the Elekta Precise linac, and TN-502RDM-H metal-oxide-semiconductor-field-effect transistor in vivo dosimeters. Computerized order-entry and treatment-automation were also analyzed. Fifty-seven potential modes and effects were identified and classified into 'treatment cancellation' and 'delivering an unintended dose'. They were graded from 'inconvenience' or 'suboptimal treatment' to 'total cancellation' or 'potentially wrong' or 'very wrong administered dose', although these latter effects were never experienced. Risk priority numbers (RPNs) ranged from 3 to 324 and totaled 4804. After interventions such as double checking, interlocking, automation, and structural changes the final total RPN was reduced to 1320. FMEA is crucial for prioritizing risk-reduction interventions. In a semi-surgical procedure like IOERT double checking has the potential to reduce risk and improve quality. Interlocks and automation should also be implemented to increase the safety of the procedure. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. Design of Automation System for Ceramic Surface Quality Control Using Fuzzy Logic Method at Balai Besar Keramik (BBK

    Directory of Open Access Journals (Sweden)

    Prahas Putri Anggie

    2017-01-01

    Full Text Available Indonesia is the world's top 10 ceramic users. Currently, the process of ceramic quality inspection in Indonesia, particularly in Balai Besar Keramik (BBK is still done manually by human vision. Therefore, it is necessary to design a visual inspection system for digital image processing of ceramic automation using a Fuzzy Logic method. Fuzzy model is one method that can be used to determine ceramic surface quality control. This study aims to apply the fuzzy model in the design of automation system for ceramic surface quality control and describes its accuracy rate and automatic database. To perform feature extraction using GLCM extraction method to obtain autocorrelation, the sum of square (variance, and a number of the object. The information is used as input for data processing using the fuzzy model in the identification of quality of ceramic surface defect. In this research used Fuzzy model with GLCM extraction feature and process by using MATLAB software. This research used 32 training data can produce the accuracy of 96.87% and based on the real time system of 92.31% used 13 real time test data.

  8. Automated Work Packages Prototype: Initial Design, Development, and Evaluation. Light Water Reactor Sustainability Program

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna Helene [Idaho National Lab. (INL), Idaho Falls, ID (United States); Al Rashdan, Ahmad [Idaho National Lab. (INL), Idaho Falls, ID (United States); Le Blanc, Katya Lee [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bly, Aaron Douglas [Idaho National Lab. (INL), Idaho Falls, ID (United States); Agarwal, Vivek [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-07-01

    The goal of the Automated Work Packages (AWP) project is to demonstrate how to enhance work quality, cost management, and nuclear safety through the use of advanced technology. The work described in this report is part of the digital architecture for a highly automated plant project of the technical program plan for advanced instrumentation, information, and control (II&C) systems technologies. This report addresses the DOE Milestone M2LW-15IN0603112: Describe the outcomes of field evaluations/demonstrations of the AWP prototype system and plant surveillance and communication framework requirements at host utilities. A brief background to the need for AWP research is provided, then two human factors field evaluation studies are described. These studies focus on the user experience of conducting a task (in this case a preventive maintenance and a surveillance test) while using an AWP system. The remaining part of the report describes an II&C effort to provide real time status updates to the technician by wireless transfer of equipment indications and a dynamic user interface.

  9. Demonstration of electronic design automation flow for massively parallel e-beam lithography

    Science.gov (United States)

    Brandt, Pieter; Belledent, Jérôme; Tranquillin, Céline; Figueiro, Thiago; Meunier, Stéfanie; Bayle, Sébastien; Fay, Aurélien; Milléquant, Matthieu; Icard, Beatrice; Wieland, Marco

    2014-07-01

    For proximity effect correction in 5 keV e-beam lithography, three elementary building blocks exist: dose modulation, geometry (size) modulation, and background dose addition. Combinations of these three methods are quantitatively compared in terms of throughput impact and process window (PW). In addition, overexposure in combination with negative bias results in PW enhancement at the cost of throughput. In proximity effect correction by over exposure (PEC-OE), the entire layout is set to fixed dose and geometry sizes are adjusted. In PEC-dose to size (DTS) both dose and geometry sizes are locally optimized. In PEC-background (BG), a background is added to correct the long-range part of the point spread function. In single e-beam tools (Gaussian or Shaped-beam), throughput heavily depends on the number of shots. In raster scan tools such as MAPPER Lithography's FLX 1200 (MATRIX platform) this is not the case and instead of pattern density, the maximum local dose on the wafer is limiting throughput. The smallest considered half-pitch is 28 nm, which may be considered the 14-nm node for Metal-1 and the 10-nm node for the Via-1 layer, achieved in a single exposure with e-beam lithography. For typical 28-nm-hp Metal-1 layouts, it was shown that dose latitudes (size of process window) of around 10% are realizable with available PEC methods. For 28-nm-hp Via-1 layouts this is even higher at 14% and up. When the layouts do not reach the highest densities (up to 10∶1 in this study), PEC-BG and PEC-OE provide the capability to trade throughput for dose latitude. At the highest densities, PEC-DTS is required for proximity correction, as this method adjusts both geometry edges and doses and will reduce the dose at the densest areas. For 28-nm-hp lines critical dimension (CD), hole&dot (CD) and line ends (edge placement error), the data path errors are typically 0.9, 1.0 and 0.7 nm (3σ) and below, respectively. There is not a clear data path performance difference between the investigated PEC methods. After the simulations, the methods were successfully validated in exposures on a MAPPER pre-alpha tool. A 28-nm half pitch Metal-1 and Via-1 layouts show good performance in resist that coincide with the simulation result. Exposures of soft-edge stitched layouts show that beam-to-beam position errors up to ±7 nm specified for FLX 1200 show no noticeable impact on CD. The research leading to these results has been performed in the frame of the industrial collaborative consortium IMAGINE.

  10. The ERL-based Design of Electron-Hadron Collider eRHIC

    Energy Technology Data Exchange (ETDEWEB)

    Ptitsyn, Vadim [et al.

    2016-06-01

    Recent developments of the ERL-based design of future high-luminosity electron-hadron collider eRHIC focused on balancing technological risks present in the design versus the design cost. As a result a lower risk design has been adopted at moderate cost increase. The modifications include a change of the main linac RF frequency, reduced number of SRF cavity types and modified electron spin transport using a spin rotator. A luminosity-staged approach is being explored with a Nominal design ($L \\sim 10^{33} {\\rm cm}^2 {\\rm s}^{-1}$) that employs reduced electron current and could possibly be based on classical electron cooling, and then with the Ultimate design ($L \\gt 10^{34} {\\rm cm}^{-2} {\\rm s}^{-1}$) that uses higher electron current and an innovative cooling technique (CeC). The paper describes the recent design modifications, and presents the full status of the eRHIC ERL-based design.

  11. IMPACT OF CANAL DESIGN LIMITATIONS ON WATER DELIVERY OPERATIONS AND AUTOMATION

    Science.gov (United States)

    Irrigation canals are often designed for water transmission. The design engineer simply ensures that the canal will pass the maximum design discharge. However, irrigation canals frequently operated far below design capacity. Because demands and the distribution of flow at bifurcations (branch points...

  12. GASICA: Generic Automated Stress Induction and Control ApplicationDesign of an application for controlling the stress state

    Directory of Open Access Journals (Sweden)

    Benny Van Der Vijgh

    2014-12-01

    Full Text Available 1.In a multitude of research and therapy paradigms it is relevant to know, and desirably to control, the stress state of a patient or participant. Examples include research paradigms in which the stress state is the dependent or independent variable, or therapy paradigms where this state indicates the boundaries of the therapy. To our knowledge, no application currently exists that focuses specifically on the automated control of the stress state while at the same time being generic enough to be used in various therapy and research purposes. Therefore, we introduce GASICA, an application aimed at the automated control of the stress state in a multitude of therapy and research paradigms. The application consists of three components: a digital stressor game, a set of measurement devices and a feedback model. These three components form a closed loop (called a biocybernetic loop by Pope, Bogart, & Bartolome, 1995 and Fairclough, 2009 that continuously presents an acute psychological stressor, measures several physiological responses to this stressor, and adjusts the stressor intensity based on these measurements by means of the feedback model, hereby aiming to control the stress state. In this manner GASICA presents multidimensional and ecological valid stressors, whilst continuously in control of the form and intensity of the presented stressors, aiming at the automated control of the stress state. Furthermore, the application is designed as a modular open-source application to easily implement different therapy and research tasks using a high-level programming interface and configuration file, and allows for the addition of (existing measurement equipment, making it usable for various paradigms.

  13. Design of power electronics for TVC and EMA systems

    Science.gov (United States)

    Nelms, R. Mark; Bell, J. Brett; Shepherd, Michael T.

    1994-01-01

    The Component Development Division of the Propulsion Laboratory at Marshall Space Flight Center (MSFC) is currently developing a class of electromechanical actuators (EMA's) for use in space transportation applications such as thrust vector control (TVC) and propellant control valves (PCV). These high power servomechanisms will require rugged, reliable, and compact power electronic modules capable of modulating several hundred amperes of current at up to 270 volts. MSFC has selected the brushless dc motor for implementation in EMA's. A previous project performed by Auburn University examined the use of the resonant dc link (RDCL) inverter, pulse density modulation (PDM), and mos-controlled thyristors (MCT's) for speed control of a brushless dc motor. The speed of the brushless dc motor is proportional to the applied stator voltage. In a PDM system, the control system determines the number of resonant voltage pulses which must be applied to the stator to achieve a desired speed. The addition of a waveshaping circuit to the front end of a standard three-phase inverter yields a RDCL inverter; the resonant voltage pulses are produced through the action of this wave shaping circuit and the inverter. This project has focused on the implementation of a system which permits zero-voltage switching with the bus voltage clamped at the input voltage level. In the same manner as the RDCL inverter, the inverter selected for this implementation is a combination of waveshaping circuit and a standard three-phase inverter. In addition, this inverter allows a pulse-width modulated (PWM)-like control scheme instead of a PDM scheme. The operation of waveshaping circuit will be described through analysis and waveforms. Design relationships will also be presented.

  14. Development and validation of an automated delirium risk assessment system (Auto-DelRAS) implemented in the electronic health record system.

    Science.gov (United States)

    Moon, Kyoung-Ja; Jin, Yinji; Jin, Taixian; Lee, Sun-Mi

    2017-09-23

    A key component of the delirium management is prevention and early detection. To develop an automated delirium risk assessment system (Auto-DelRAS) that automatically alerts health care providers of an intensive care unit (ICU) patient's delirium risk based only on data collected in an electronic health record (EHR) system, and to evaluate the clinical validity of this system. Cohort and system development designs were used. Medical and surgical ICUs in two university hospitals in Seoul, Korea. A total of 3284 patients for the development of Auto-DelRAS, 325 for external validation, 694 for validation after clinical applications. The 4211 data items were extracted from the EHR system and delirium was measured using CAM-ICU (Confusion Assessment Method for Intensive Care Unit). The potential predictors were selected and a logistic regression model was established to create a delirium risk scoring algorithm to construct the Auto-DelRAS. The Auto-DelRAS was evaluated at three months and one year after its application to clinical practice to establish the predictive validity of the system. Eleven predictors were finally included in the logistic regression model. The results of the Auto-DelRAS risk assessment were shown as high/moderate/low risk on a Kardex screen. The predictive validity, analyzed after the clinical application of Auto-DelRAS after one year, showed a sensitivity of 0.88, specificity of 0.72, positive predictive value of 0.53, negative predictive value of 0.94, and a Youden index of 0.59. A relatively high level of predictive validity was maintained with the Auto-DelRAS system, even one year after it was applied to clinical practice. Copyright © 2017. Published by Elsevier Ltd.

  15. Conceptual design study of the GSI electron-nucleon collider

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-01

    Design concepts, beam-beam instability, ion bunch cooling, intrabeam scattering, conventional collective effects, lattice design, polarization control, injection chain, basic technical systems, cost estimations, time schedule.

  16. Automated information extraction of key trial design elements from clinical trial publications.

    Science.gov (United States)

    de Bruijn, Berry; Carini, Simona; Kiritchenko, Svetlana; Martin, Joel; Sim, Ida

    2008-11-06

    Clinical trials are one of the most valuable sources of scientific evidence for improving the practice of medicine. The Trial Bank project aims to improve structured access to trial findings by including formalized trial information into a knowledge base. Manually extracting trial information from published articles is costly, but automated information extraction techniques can assist. The current study highlights a single architecture to extract a wide array of information elements from full-text publications of randomized clinical trials (RCTs). This architecture combines a text classifier with a weak regular expression matcher. We tested this two-stage architecture on 88 RCT reports from 5 leading medical journals, extracting 23 elements of key trial information such as eligibility rules, sample size, intervention, and outcome names. Results prove this to be a promising avenue to help critical appraisers, systematic reviewers, and curators quickly identify key information elements in published RCT articles.

  17. Design and demonstration of automated data analysis algorithms for ultrasonic inspection of complex composite panels with bonds

    Science.gov (United States)

    Aldrin, John C.; Forsyth, David S.; Welter, John T.

    2016-02-01

    To address the data review burden and improve the reliability of the ultrasonic inspection of large composite structures, automated data analysis (ADA) algorithms have been developed to make calls on indications that satisfy the detection criteria and minimize false calls. The original design followed standard procedures for analyzing signals for time-of-flight indications and backwall amplitude dropout. However, certain complex panels with varying shape, ply drops and the presence of bonds can complicate this interpretation process. In this paper, enhancements to the automated data analysis algorithms are introduced to address these challenges. To estimate the thickness of the part and presence of bonds without prior information, an algorithm tracks potential backwall or bond-line signals, and evaluates a combination of spatial, amplitude, and time-of-flight metrics to identify bonded sections. Once part boundaries, thickness transitions and bonded regions are identified, feature extraction algorithms are applied to multiple sets of through-thickness and backwall C-scan images, for evaluation of both first layer through thickness and layers under bonds. ADA processing results are presented for a variety of complex test specimens with inserted materials and other test discontinuities. Lastly, enhancements to the ADA software interface are presented, which improve the software usability for final data review by the inspectors and support the certification process.

  18. Evaluation of green infrastructure designs using the Automated Geospatial Watershed Assessment Tool

    Science.gov (United States)

    In arid and semi-arid regions, green infrastructure (GI) designs can address several issues facing urban environments, including augmenting water supply, mitigating flooding, decreasing pollutant loads, and promoting greenness in the built environment. An optimum design captures stormwater, addressi...

  19. Maneuver Automation Software

    Science.gov (United States)

    Uffelman, Hal; Goodson, Troy; Pellegrin, Michael; Stavert, Lynn; Burk, Thomas; Beach, David; Signorelli, Joel; Jones, Jeremy; Hahn, Yungsun; Attiyah, Ahlam; hide

    2009-01-01

    The Maneuver Automation Software (MAS) automates the process of generating commands for maneuvers to keep the spacecraft of the Cassini-Huygens mission on a predetermined prime mission trajectory. Before MAS became available, a team of approximately 10 members had to work about two weeks to design, test, and implement each maneuver in a process that involved running many maneuver-related application programs and then serially handing off data products to other parts of the team. MAS enables a three-member team to design, test, and implement a maneuver in about one-half hour after Navigation has process-tracking data. MAS accepts more than 60 parameters and 22 files as input directly from users. MAS consists of Practical Extraction and Reporting Language (PERL) scripts that link, sequence, and execute the maneuver- related application programs: "Pushing a single button" on a graphical user interface causes MAS to run navigation programs that design a maneuver; programs that create sequences of commands to execute the maneuver on the spacecraft; and a program that generates predictions about maneuver performance and generates reports and other files that enable users to quickly review and verify the maneuver design. MAS can also generate presentation materials, initiate electronic command request forms, and archive all data products for future reference.

  20. An ultra-lightweight design for imperceptible plastic electronics.

    Science.gov (United States)

    Kaltenbrunner, Martin; Sekitani, Tsuyoshi; Reeder, Jonathan; Yokota, Tomoyuki; Kuribara, Kazunori; Tokuhara, Takeyoshi; Drack, Michael; Schwödiauer, Reinhard; Graz, Ingrid; Bauer-Gogonea, Simona; Bauer, Siegfried; Someya, Takao

    2013-07-25

    Electronic devices have advanced from their heavy, bulky origins to become smart, mobile appliances. Nevertheless, they remain rigid, which precludes their intimate integration into everyday life. Flexible, textile and stretchable electronics are emerging research areas and may yield mainstream technologies. Rollable and unbreakable backplanes with amorphous silicon field-effect transistors on steel substrates only 3 μm thick have been demonstrated. On polymer substrates, bending radii of 0.1 mm have been achieved in flexible electronic devices. Concurrently, the need for compliant electronics that can not only be flexed but also conform to three-dimensional shapes has emerged. Approaches include the transfer of ultrathin polyimide layers encapsulating silicon CMOS circuits onto pre-stretched elastomers, the use of conductive elastomers integrated with organic field-effect transistors (OFETs) on polyimide islands, and fabrication of OFETs and gold interconnects on elastic substrates to realize pressure, temperature and optical sensors. Here we present a platform that makes electronics both virtually unbreakable and imperceptible. Fabricated directly on ultrathin (1 μm) polymer foils, our electronic circuits are light (3 g m(-2)) and ultraflexible and conform to their ambient, dynamic environment. Organic transistors with an ultra-dense oxide gate dielectric a few nanometres thick formed at room temperature enable sophisticated large-area electronic foils with unprecedented mechanical and environmental stability: they withstand repeated bending to radii of 5 μm and less, can be crumpled like paper, accommodate stretching up to 230% on prestrained elastomers, and can be operated at high temperatures and in aqueous environments. Because manufacturing costs of organic electronics are potentially low, imperceptible electronic foils may be as common in the future as plastic wrap is today. Applications include matrix-addressed tactile sensor foils for health care and

  1. Development of a CAD system for automated conceptual design of supersonic aitcraft

    OpenAIRE

    Wampler, Steven Glenn

    1988-01-01

    Development of a conceptual aircraft design system based on ACSYNT, an aircraft synthesis program written by the NASA Ames Research Center; is discussed. The system, named ACSYNT/VPI, was written using the PHIGS graphics standard for machine independence and designed based on top·down principles and standards. A functional description of ACSYNT is presented as well as detailed software requirements for ACSYNT/VPI. The softwareâ s design is covered in depth including design ph...

  2. Enhanced Aircraft Design Capability for the Automated Structural Optimization System. Phase 1.

    Science.gov (United States)

    1996-01-31

    34NEWSUMT--A FORTRAN Program for inequality Constrained Function Minimization--User’s Guide," NASA CR 159070, June 1979. [2-12] Roskam , Jan , Airplane... Jan Roskam , is a design tool intended to be used by a sophisticated designer. That is, the designer must make all trade-offs and decisions, while AAA...AIAA, Washington D.C., 1992. Roskam , Jan , Aiplane Design. Part V. Component Weight Estimation, Roskam Aviation and Engineering Corporation, Lawrence

  3. BIM approach for automated drafting and design for modular construction manufacturing

    NARCIS (Netherlands)

    Alwisy, A.; Al-Hussein, M.; Al-Jibouri, Saad H.S.; Issa, R.R.; Flood, I.

    2012-01-01

    Industrialization creates new requirements for design. Designers need to consider not only building performance, but also production plan needs. This requires a well-structured Building Information Model (BIM) to support the manufacturing needs for design and drafting. BIM, in combination with CAD

  4. Drug dosing in patients with renal insufficiency in a hospital setting using electronic prescribing and automated reporting of estimated glomerular filtration rate

    DEFF Research Database (Denmark)

    Nielsen, Anita L; Henriksen, Daniel P; Marinakis, Christianna

    2014-01-01

    In patients with impaired renal function, drug dose adjustment is often required. Non-adherence to clinical prescribing recommendations may result in severe adverse events. In previous studies, the prevalence rate of non-adherence to recommended dosing has been reported to be 19-67%. Using....... We conclude that despite implementation of electronic prescribing and automated reporting of eGFR, patients with renal insufficiency may still be exposed to inappropriate drug use, with potential increased risk of adverse effects. Initiatives to reduce medication errors such as the use of electronic...... the clinical support system Renbase(®) as reference, we investigated the use and dosing of drugs in patients with impaired renal function in a university hospital setting using electronic prescription and automatic reporting of estimated glomerular filtration rate (eGFR). In all, 232 patients with an e...

  5. 3D-printed microfluidic automation.

    Science.gov (United States)

    Au, Anthony K; Bhattacharjee, Nirveek; Horowitz, Lisa F; Chang, Tim C; Folch, Albert

    2015-04-21

    Microfluidic automation - the automated routing, dispensing, mixing, and/or separation of fluids through microchannels - generally remains a slowly-spreading technology because device fabrication requires sophisticated facilities and the technology's use demands expert operators. Integrating microfluidic automation in devices has involved specialized multi-layering and bonding approaches. Stereolithography is an assembly-free, 3D-printing technique that is emerging as an efficient alternative for rapid prototyping of biomedical devices. Here we describe fluidic valves and pumps that can be stereolithographically printed in optically-clear, biocompatible plastic and integrated within microfluidic devices at low cost. User-friendly fluid automation devices can be printed and used by non-engineers as replacement for costly robotic pipettors or tedious manual pipetting. Engineers can manipulate the designs as digital modules into new devices of expanded functionality. Printing these devices only requires the digital file and electronic access to a printer.

  6. Design and implementation of intelligent electronic warfare decision making algorithm

    Science.gov (United States)

    Peng, Hsin-Hsien; Chen, Chang-Kuo; Hsueh, Chi-Shun

    2017-05-01

    Electromagnetic signals and the requirements of timely response have been a rapid growth in modern electronic warfare. Although jammers are limited resources, it is possible to achieve the best electronic warfare efficiency by tactical decisions. This paper proposes the intelligent electronic warfare decision support system. In this work, we develop a novel hybrid algorithm, Digital Pheromone Particle Swarm Optimization, based on Particle Swarm Optimization (PSO), Ant Colony Optimization (ACO) and Shuffled Frog Leaping Algorithm (SFLA). We use PSO to solve the problem and combine the concept of pheromones in ACO to accumulate more useful information in spatial solving process and speed up finding the optimal solution. The proposed algorithm finds the optimal solution in reasonable computation time by using the method of matrix conversion in SFLA. The results indicated that jammer allocation was more effective. The system based on the hybrid algorithm provides electronic warfare commanders with critical information to assist commanders in effectively managing the complex electromagnetic battlefield.

  7. Microcomputer array processor system. [design for electronic warfare

    Science.gov (United States)

    Slezak, K. D.

    1980-01-01

    The microcomputer array system is discussed with specific attention given to its electronic warware applications. Several aspects of the system architecture are described as well as some of its distinctive characteristics.

  8. Electronic Modeling and Design for Extreme Temperatures Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We propose to develop electronics for operation at temperatures that range from -230oC to +130oC. This new technology will minimize the requirements for external...

  9. An automated tool for evaluating compliance and providing assistance with building energy standards during design

    Energy Technology Data Exchange (ETDEWEB)

    Quadrel, R.W.; Brambley, M.R.; Stratton, R.C.

    1992-04-30

    In an effort to encourage the maximum cost-effective level of energy efficiency in new building design, energy-efficiency standards have become more location-specific and performance-based. As a result, standards often provide more than one path for ensuring and demonstrating that a design complies, but at the cost of increased complexity. In addition, the burden of remedying a noncompliant design rests on the designers' knowledge and experience, with only general guidance provided by the standards. As part of efforts in the US Department of Energy's (DOE's) Advanced Energy Design and Operation Technologies (AEDOT) project, a team at DOE's Pacific Northwest Laboratory is developing a computer program known as the Energy Standards Intelligent Design Tool (ES-IDT). The ES-IDT is one component of a prototype computer-based building design environment. It performs automatic compliance checking for parts of ASHRAE/IES Standard 90.1-1989 and provides designers assistance in bringing noncomplying designs into compliance. This paper describes the ES-IDT, the functions it provides, and how it is integrated into the design process via the AEDOT prototype building design environment. 9 refs.

  10. An automated tool for evaluating compliance and providing assistance with building energy standards during design

    Energy Technology Data Exchange (ETDEWEB)

    Quadrel, R.W.; Brambley, M.R.; Stratton, R.C.

    1992-04-30

    In an effort to encourage the maximum cost-effective level of energy efficiency in new building design, energy-efficiency standards have become more location-specific and performance-based. As a result, standards often provide more than one path for ensuring and demonstrating that a design complies, but at the cost of increased complexity. In addition, the burden of remedying a noncompliant design rests on the designers` knowledge and experience, with only general guidance provided by the standards. As part of efforts in the US Department of Energy`s (DOE`s) Advanced Energy Design and Operation Technologies (AEDOT) project, a team at DOE`s Pacific Northwest Laboratory is developing a computer program known as the Energy Standards Intelligent Design Tool (ES-IDT). The ES-IDT is one component of a prototype computer-based building design environment. It performs automatic compliance checking for parts of ASHRAE/IES Standard 90.1-1989 and provides designers assistance in bringing noncomplying designs into compliance. This paper describes the ES-IDT, the functions it provides, and how it is integrated into the design process via the AEDOT prototype building design environment. 9 refs.

  11. An Open Software Platform for the Automated Design of Paper-Based Microfluidic Devices.

    Science.gov (United States)

    DeChiara, Nicholas S; Wilson, Daniel J; Mace, Charles R

    2017-11-24

    Paper-based microfluidic devices have many applications in biomedical and environmental analysis. However, the process of prototyping device designs can be tedious, error-prone, and time-consuming. Here, we present a cross-platform, open-source software tool-AutoPAD-developed to quickly create and modify device designs and provide a free alternative to commercial design software. The capabilities that we designed to be inherent to AutoPAD (e.g., automatic zone alignment and design refactoring) highlight its potential use in nearly any paper-based microfluidic device application and for creating nearly any desired design, which we demonstrate through the recreation of numerous device designs from the literature.

  12. Elucidating structural order and disorder phenomena in mullite-type Al{sub 4}B{sub 2}O{sub 9} by automated electron diffraction tomography

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Haishuang; Krysiak, Yaşar [Institute of Inorganic Chemistry and Analytical Chemistry, Jakob-Welder-Weg 11, Johannes Gutenberg-University Mainz, 55128 Mainz (Germany); Hoffmann, Kristin [Crystallography, Department of Geosciences, Klagenfurter Str. 2, GEO, University of Bremen, 28359 Bremen (Germany); Institute of Inorganic Chemistry and Crystallography, Leobener Str. NW2, University of Bremen, 28359 Bremen (Germany); Barton, Bastian [Institute of Inorganic Chemistry and Analytical Chemistry, Jakob-Welder-Weg 11, Johannes Gutenberg-University Mainz, 55128 Mainz (Germany); Molina-Luna, Leopoldo [Department of Materials and Geoscience, Technische Universität Darmstadt, Petersenstr. 23, 64287 Darmstadt (Germany); Neder, Reinhard B. [Department of Physics, Lehrstuhl für Kristallographie und Strukturphysik, Friedrich-Alexander University Erlangen-Nürnberg, Staudtstr.3, 91058 Erlangen (Germany); Kleebe, Hans-Joachim [Department of Materials and Geoscience, Technische Universität Darmstadt, Petersenstr. 23, 64287 Darmstadt (Germany); Gesing, Thorsten M. [Institute of Inorganic Chemistry and Crystallography, Leobener Str. NW2, University of Bremen, 28359 Bremen (Germany); MAPEX Center for Materials and Processes, Bibliothekstr.1, University of Bremen, 28359 Bremen (Germany); Schneider, Hartmut [Crystallography, Department of Geosciences, Klagenfurter Str. 2, GEO, University of Bremen, 28359 Bremen (Germany); Fischer, Reinhard X. [Crystallography, Department of Geosciences, Klagenfurter Str. 2, GEO, University of Bremen, 28359 Bremen (Germany); MAPEX Center for Materials and Processes, Bibliothekstr.1, University of Bremen, 28359 Bremen (Germany); and others

    2017-05-15

    The crystal structure and disorder phenomena of Al{sub 4}B{sub 2}O{sub 9}, an aluminum borate from the mullite-type family, were studied using automated diffraction tomography (ADT), a recently established method for collection and analysis of electron diffraction data. Al{sub 4}B{sub 2}O{sub 9}, prepared by sol-gel approach, crystallizes in the monoclinic space group C2/m. The ab initio structure determination based on three-dimensional electron diffraction data from single ordered crystals reveals that edge-connected AlO{sub 6} octahedra expanding along the b axis constitute the backbone. The ordered structure (A) was confirmed by TEM and HAADF-STEM images. Furthermore, disordered crystals with diffuse scattering along the b axis are observed. Analysis of the modulation pattern implies a mean superstructure (AAB) with a threefold b axis, where B corresponds to an A layer shifted by ½a and ½c. Diffraction patterns simulated for the AAB sequence including additional stacking disorder are in good agreement with experimental electron diffraction patterns. - Graphical abstract: Crystal structure and disorder phenomena of B-rich Al{sub 4}B{sub 2}O{sub 9} studied by automated electron diffraction tomography (ADT) and described by diffraction simulation using DISCUS. - Highlights: • Ab-initio structure solution by electron diffraction from single nanocrystals. • Detected modulation corresponding mainly to three-fold superstructure. • Diffuse diffraction streaks caused by stacking faults in disordered crystals. • Observed streaks explained by simulated electron diffraction patterns.

  13. Automated, electronic alerts for acute kidney injury: a single-blind, parallel-group, randomised controlled trial

    Science.gov (United States)

    Wilson, F Perry; Shashaty, Michael; Testani, Jeffrey; Aqeel, Iram; Borovskiy, Yuliya; Ellenberg, Susan S.; Feldman, Harold I.; Fernandez, Hilda; Gitelman, Yevgeniy; Lin, Jennie; Negoianu, Dan; Parikh, Chirag R.; Reese, Peter P.; Urbani, Richard; Fuchs, Barry

    2015-01-01

    Summary Background Acute kidney injury often goes unrecognised in its early stages when effective treatment options might be available. We aimed to determine whether an automated electronic alert for acute kidney injury would reduce the severity of such injury and improve clinical outcomes in patients in hospital. Methods In this investigator-masked, parallel-group, randomised controlled trial, patients were recruited from the hospital of the University of Pennsylvania in Philadelphia, PA, USA. Eligible participants were adults aged 18 years or older who were in hospital with stage 1 or greater acute kidney injury as defined by Kidney Disease Improving Global Outcomes creatinine-based criteria. Exclusion criteria were initial hospital creatinine 4·0 mg/dL (to convert to μmol/L, multiply by 88·4) or greater, fewer than two creatinine values measured, inability to determine the covering provider, admission to hospice or the observation unit, previous randomisation, or end-stage renal disease. Patients were randomly assigned (1:1) via a computer-generated sequence to receive an acute kidney injury alert (a text-based alert sent to the covering provider and unit pharmacist indicating new acute kidney injury) or usual care, stratified by medical versus surgical admission and intensive care unit versus non-intensive care unit location in blocks of 4–8 participants. The primary outcome was a composite of relative maximum change in creatinine, dialysis, and death at 7 days after randomisation. All analyses were by intention to treat. This study is registered with ClinicalTrials.gov, number NCT01862419. Findings Between Sept 17, 2013, and April 14, 2014, 23 664 patients were screened. 1201 eligible participants were assigned to the acute kidney injury alert group and 1192 were assigned to the usual care group. Composite relative maximum change in creatinine, dialysis, and death at 7 days did not differ between the alert group and the usual care group (p=0·88), or

  14. Design of the MEMS Piezoresistive Electronic Heart Sound Sensor.

    Science.gov (United States)

    Zhang, Guojun; Liu, Mengran; Guo, Nan; Zhang, Wendong

    2016-11-07

    This paper proposes the electronic heart sound sensor, based on the piezoresistive principle and MEMS (Micro-Electro-Mechanical System) technology. Firstly, according to the characteristics of heart sound detection, the double-beam-block microstructure has been proposed, and the theoretical analysis and finite element method (FEM) simulation have been carried out. Combined with the natural frequency response of the heart sound (20~600 Hz), its structure sizes have been determined. Secondly, the processing technology of the microstructure with the stress concentration grooves has been developed. The material and sizes of the package have been determined by the three-layer medium transmission principle. Lastly, the MEMS piezoresistive electronic heart sound sensor has been tested compared with the 3200-type electronic stethoscope from 3M (São Paulo, MN, USA). The test results show that the heart sound waveform tested by the MEMS electronic heart sound sensor are almost the same as that tested by the 3200-type electronic stethoscope. Moreover, its signal-to-noise ratio is significantly higher. Compared with the traditional stethoscope, the MEMS heart sound sensor can provide the first and second heart sounds containing more abundant information about the lesion. Compared with the 3200-type electronic stethoscope from 3M, it has better performance and lower cost.

  15. A Fully Automated Diabetes Prevention Program, Alive-PD: Program Design and Randomized Controlled Trial Protocol.

    Science.gov (United States)

    Block, Gladys; Azar, Kristen Mj; Block, Torin J; Romanelli, Robert J; Carpenter, Heather; Hopkins, Donald; Palaniappan, Latha; Block, Clifford H

    2015-01-21

    In the United States, 86 million adults have pre-diabetes. Evidence-based interventions that are both cost effective and widely scalable are needed to prevent diabetes. Our goal was to develop a fully automated diabetes prevention program and determine its effectiveness in a randomized controlled trial. Subjects with verified pre-diabetes were recruited to participate in a trial of the effectiveness of Alive-PD, a newly developed, 1-year, fully automated behavior change program delivered by email and Web. The program involves weekly tailored goal-setting, team-based and individual challenges, gamification, and other opportunities for interaction. An accompanying mobile phone app supports goal-setting and activity planning. For the trial, participants were randomized by computer algorithm to start the program immediately or after a 6-month delay. The primary outcome measures are change in HbA1c and fasting glucose from baseline to 6 months. The secondary outcome measures are change in HbA1c, glucose, lipids, body mass index (BMI), weight, waist circumference, and blood pressure at 3, 6, 9, and 12 months. Randomization and delivery of the intervention are independent of clinic staff, who are blinded to treatment assignment. Outcomes will be evaluated for the intention-to-treat and per-protocol populations. A total of 340 subjects with pre-diabetes were randomized to the intervention (n=164) or delayed-entry control group (n=176). Baseline characteristics were as follows: mean age 55 (SD 8.9); mean BMI 31.1 (SD 4.3); male 68.5%; mean fasting glucose 109.9 (SD 8.4) mg/dL; and mean HbA1c 5.6 (SD 0.3)%. Data collection and analysis are in progress. We hypothesize that participants in the intervention group will achieve statistically significant reductions in fasting glucose and HbA1c as compared to the control group at 6 months post baseline. The randomized trial will provide rigorous evidence regarding the efficacy of this Web- and Internet-based program in reducing or

  16. Agent-Oriented Embedded Control System Design and Development of a Vision-Based Automated Guided Vehicle

    Directory of Open Access Journals (Sweden)

    Wu Xing

    2012-07-01

    Full Text Available This paper presents a control system design and development approach for a vision-based automated guided vehicle (AGV based on the multi-agent system (MAS methodology and embedded system resources. A three-phase agent-oriented design methodology Prometheus is used to analyse system functions, construct operation scenarios, define agent types and design the MAS coordination mechanism. The control system is then developed in an embedded implementation containing a digital signal processor (DSP and an advanced RISC machine (ARM by using the multitasking processing capacity of multiple microprocessors and system services of a real-time operating system (RTOS. As a paradigm, an onboard embedded controller is designed and developed for the AGV with a camera detecting guiding landmarks, and the entire procedure has a high efficiency and a clear hierarchy. A vision guidance experiment for our AGV is carried out in a space-limited laboratory environment to verify the perception capacity and the onboard intelligence of the agent-oriented embedded control system.

  17. Assessing Whether Students Seek Constructive Criticism: The Design of an Automated Feedback System for a Graphic Design Task

    Science.gov (United States)

    Cutumisu, Maria; Blair, Kristen P.; Chin, Doris B.; Schwartz, Daniel L.

    2017-01-01

    We introduce a choice-based assessment strategy that measures students' choices to seek constructive feedback and to revise their work. We present the feedback system of a game we designed to assess whether students choose positive or negative feedback and choose to revise their posters in the context of a poster design task, where they learn…

  18. Self-similar and fractal design for stretchable electronics

    Science.gov (United States)

    Rogers, John A.; Fan, Jonathan; Yeo, Woon-Hong; Su, Yewang; Huang, Yonggang; Zhang, Yihui

    2017-04-04

    The present invention provides electronic circuits, devices and device components including one or more stretchable components, such as stretchable electrical interconnects, electrodes and/or semiconductor components. Stretchability of some of the present systems is achieved via a materials level integration of stretchable metallic or semiconducting structures with soft, elastomeric materials in a configuration allowing for elastic deformations to occur in a repeatable and well-defined way. The stretchable device geometries and hard-soft materials integration approaches of the invention provide a combination of advance electronic function and compliant mechanics supporting a broad range of device applications including sensing, actuation, power storage and communications.

  19. Organic structures design applications in optical and electronic devices

    CERN Document Server

    Chow, Tahsin J

    2014-01-01

    ""Presenting an overview of the syntheses and properties of organic molecules and their applications in optical and electronic devices, this book covers aspects concerning theoretical modeling for electron transfer, solution-processed micro- and nanomaterials, donor-acceptor cyclophanes, molecular motors, organogels, polyazaacenes, fluorogenic sensors based on calix[4]arenes, and organic light-emitting diodes. The publication of this book is timely because these topics have become very popular nowadays. The book is definitely an excellent reference for scientists working in these a

  20. RF Design of a High Average Beam-Power SRF Electron Source

    Energy Technology Data Exchange (ETDEWEB)

    Sipahi, Nihan [Colorado State U., Fort Collins; Biedron, Sandra [Colorado State U., Fort Collins; Gonin, Ivan [Fermilab; Kephart, Robert [Fermilab; Khabiboulline, Timergali [Fermilab; Milton, Stephen [Colorado State U., Fort Collins; Yakovlev, Vyacheslav [Fermilab

    2016-06-01

    There is a significant interest in developing high-average power electron sources, particularly in the area of electron sources integrated with Superconducting Radio Frequency (SRF) systems. For these systems, the electron gun and cathode parts are critical components for stable intensity and high-average powers. In this initial design study, we will present the design of a 9-cell accelerator cavity having a frequency of 1.3 GHz and the corresponding field optimization studies.

  1. Design of compact system with wide electron beam for radiation technologies

    CERN Document Server

    Korolyov, A N; Pirozhenko, Vitaly M

    2001-01-01

    Design of a compact system for radiation processing of products and materials has been developed. The system provides two modes of irradiation, i.e. irradiation of continuously moving tapes and fixed samples. The irradiation is performed in a hermetically sealed chamber filled by nitrogen. This ecologically pure system includes the radiation protection,autonomous water cooling system and automated PC-control. It can be placed in any production or clinical room.

  2. Design and Analysis of Megawatt Class Free Electron Laser Weapons

    Science.gov (United States)

    2015-12-01

    means. For thermionic cathodes, heat is supplied to provide sufficient escape energy for the electrons. An alloy of tungsten and barium is often used...cryo- plant . A smaller cryo- plant would reduce the system footprint and could potentially improve power efficiency. An SRF linear accelerator that

  3. Designing Electron Spin Textures and Spin Interferometers by Shape Deformations

    NARCIS (Netherlands)

    Ying, Zu-Jian; Gentile, Paola; Ortix, Carmine; Cuoco, Mario

    2016-01-01

    We demonstrate that the spin orientation of an electron propagating in a one-dimensional nanostructure with Rashba spin-orbit (SO) coupling can be manipulated on demand by changing the geometry of the nanosystem. Shape deformations that result in a non-uniform curvature give rise to complex

  4. Designing an Electronic Personal Health Record for Professional Iranian Athletes

    Science.gov (United States)

    Abdolkhani, Robab; Halabchi, Farzin; Safdari, Reza; Dargahi, Hossein; Shadanfar, Kamran

    2014-01-01

    Background: By providing sports organizations with electronic records and instruments that can be accessed at any time or place, specialized care can be offered to athletes regardless of injury location, and this makes the follow-up from first aid through to full recovery more efficient. Objectives: The aim of this study was to develop an electronic personal health record for professional Iranian athletes. Patients and Methods: First, a comparative study was carried out on the types of professional athletes’existing handheld and electronic health information management systems currently being used in Iran and leading countries in the field of sports medicine including; Australia, Canada and the United States. Then a checklist was developed containing a minimum dataset of professional athletes’ personal health records and distributed to the people involved, who consisted of 50 specialists in sports medicine and health information management, using the Delphi method. Through the use of data obtained from this survey, a basic paper model of professional athletes' personal health record was constructed and then an electronic model was created accordingly. Results: Access to information in the electronic record was through a web-based, portal system. The capabilities of this system included: access to information at any time and location, increased interaction between the medical team, comprehensive reporting and effective management of injuries, flexibility and interaction with financial, radiology and laboratory information systems. Conclusions: It is suggested that a framework should be created to promote athletes’ medical knowledge and provide the education necessary to manage their information. This would lead to improved data quality and ultimately promote the health of community athletes. PMID:25741410

  5. Integrated Design and Analysis Environment for Safety Critical Human-Automation Systems Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Numerous advances have been made in recent years in the areas of flight deck design, aircraft modeling, resilient control, and vehicle health management. The...

  6. Pyviko: an automated Python tool to design gene knockouts in complex viruses with overlapping genes.

    Science.gov (United States)

    Taylor, Louis J; Strebel, Klaus

    2017-01-07

    Gene knockouts are a common tool used to study gene function in various organisms. However, designing gene knockouts is complicated in viruses, which frequently contain sequences that code for multiple overlapping genes. Designing mutants that can be traced by the creation of new or elimination of existing restriction sites further compounds the difficulty in experimental design of knockouts of overlapping genes. While software is available to rapidly identify restriction sites in a given nucleotide sequence, no existing software addresses experimental design of mutations involving multiple overlapping amino acid sequences in generating gene knockouts. Pyviko performed well on a test set of over 240,000 gene pairs collected from viral genomes deposited in the National Center for Biotechnology Information Nucleotide database, identifying a point mutation which added a premature stop codon within the first 20 codons of the target gene in 93.2% of all tested gene-overprinted gene pairs. This shows that Pyviko can be used successfully in a wide variety of contexts to facilitate the molecular cloning and study of viral overprinted genes. Pyviko is an extensible and intuitive Python tool for designing knockouts of overlapping genes. Freely available as both a Python package and a web-based interface ( http://louiejtaylor.github.io/pyViKO/ ), Pyviko simplifies the experimental design of gene knockouts in complex viruses with overlapping genes.

  7. Short-term prediction of solar energy in Saudi Arabia using automated-design fuzzy logic systems.

    Science.gov (United States)

    Almaraashi, Majid

    2017-01-01

    Solar energy is considered as one of the main sources for renewable energy in the near future. However, solar energy and other renewable energy sources have a drawback related to the difficulty in predicting their availability in the near future. This problem affects optimal exploitation of solar energy, especially in connection with other resources. Therefore, reliable solar energy prediction models are essential to solar energy management and economics. This paper presents work aimed at designing reliable models to predict the global horizontal irradiance (GHI) for the next day in 8 stations in Saudi Arabia. The designed models are based on computational intelligence methods of automated-design fuzzy logic systems. The fuzzy logic systems are designed and optimized with two models using fuzzy c-means clustering (FCM) and simulated annealing (SA) algorithms. The first model uses FCM based on the subtractive clustering algorithm to automatically design the predictor fuzzy rules from data. The second model is using FCM followed by simulated annealing algorithm to enhance the prediction accuracy of the fuzzy logic system. The objective of the predictor is to accurately predict next-day global horizontal irradiance (GHI) using previous-day meteorological and solar radiation observations. The proposed models use observations of 10 variables of measured meteorological and solar radiation data to build the model. The experimentation and results of the prediction are detailed where the root mean square error of the prediction was approximately 88% for the second model tuned by simulated annealing compared to 79.75% accuracy using the first model. This results demonstrate a good modeling accuracy of the second model despite that the training and testing of the proposed models were carried out using spatially and temporally independent data.

  8. Strategies for Optimization and Automated Design of Gas Turbine Engines (Les strategies pour l’optimisation et la conception automatique de turbines a gaz)

    Science.gov (United States)

    2010-09-01

    Sep 2010 Strategies for Optimization and Automated Design of Gas Turbine Engines (Les Stratégies pour l’optimisation et la conception automatique de...Engines (Les Stratégies pour l’optimisation et la conception automatique de turbines à gaz) The material in this publication was assembled to support

  9. A Tool for the Automated Design and Evaluation of Habitat Interior Layouts

    Science.gov (United States)

    Simon, Matthew A.; Wilhite, Alan W.

    2013-01-01

    The objective of space habitat design is to minimize mass and system size while providing adequate space for all necessary equipment and a functional layout that supports crew health and productivity. Unfortunately, development and evaluation of interior layouts is often ignored during conceptual design because of the subjectivity and long times required using current evaluation methods (e.g., human-in-the-loop mockup tests and in-depth CAD evaluations). Early, more objective assessment could prevent expensive design changes that may increase vehicle mass and compromise functionality. This paper describes a new interior design evaluation method to enable early, structured consideration of habitat interior layouts. This interior layout evaluation method features a comprehensive list of quantifiable habitat layout evaluation criteria, automatic methods to measure these criteria from a geometry model, and application of systems engineering tools and numerical methods to construct a multi-objective value function measuring the overall habitat layout performance. In addition to a detailed description of this method, a C++/OpenGL software tool which has been developed to implement this method is also discussed. This tool leverages geometry modeling coupled with collision detection techniques to identify favorable layouts subject to multiple constraints and objectives (e.g., minimize mass, maximize contiguous habitable volume, maximize task performance, and minimize crew safety risks). Finally, a few habitat layout evaluation examples are described to demonstrate the effectiveness of this method and tool to influence habitat design.

  10. Design of space-type electronic power transformers

    Science.gov (United States)

    Ahearn, J. F.; Lagadinos, J. C.

    1977-01-01

    Both open and encapsulated varieties of high reliability, low weight, and high efficiency moderate and high voltage transformers were investigated to determine the advantages and limitations of their construction in the ranges of power and voltage required for operation in the hard vacuum environment of space. Topics covered include: (1) selection of the core material; (2) preliminary calculation of core dimensions; (3) selection of insulating materials including magnet wire insulation, coil forms, and layer and interwinding insulation; (4) coil design; (5) calculation of copper losses, core losses and efficiency; (6) calculation of temperature rise; and (7) optimization of design with changes in core selection or coil design as required to meet specifications.

  11. PopupCAD: a tool for automated design, fabrication, and analysis of laminate devices

    Science.gov (United States)

    Aukes, Daniel M.; Wood, Robert J.

    2015-05-01

    Recent advances in laminate manufacturing techniques have driven the development of new classes of millimeter-scale sensorized medical devices, robots capable of terrestrial locomotion and sustained flight, and new techniques for sensing and actuation. Recently, the analysis of laminate micro-devices has focused more manufacturability concerns and not on mechanics. Considering the nature of such devices, we draw from existing research in composites, origami kinematics, and finite element methods in order to identify issues related to sequential assembly and self-folding prior to fabrication as well as the stiffness of composite folded systems during operation. These techniques can be useful for understanding how such devices will bend and flex under normal operating conditions, and when added to new design tools like popupCAD, will give designers another means to develop better devices throughout the design process.

  12. Human-Automation Integration: Principle and Method for Design and Evaluation

    Science.gov (United States)

    Billman, Dorrit; Feary, Michael

    2012-01-01

    Future space missions will increasingly depend on integration of complex engineered systems with their human operators. It is important to ensure that the systems that are designed and developed do a good job of supporting the needs of the work domain. Our research investigates methods for needs analysis. We included analysis of work products (plans for regulation of the space station) as well as work processes (tasks using current software), in a case study of Attitude Determination and Control Officers (ADCO) planning work. This allows comparing how well different designs match the structure of the work to be supported. Redesigned planning software that better matches the structure of work was developed and experimentally assessed. The new prototype enabled substantially faster and more accurate performance in plan revision tasks. This success suggests the approach to needs assessment and use in design and evaluation is promising, and merits investigatation in future research.

  13. Integrated Design Engineering Analysis (IDEA) Environment Automated Generation of Structured CFD Grids using Topology Methods

    Science.gov (United States)

    Kamhawi, Hilmi N.

    2012-01-01

    This report documents the work performed from March 2010 to March 2012. The Integrated Design and Engineering Analysis (IDEA) environment is a collaborative environment based on an object-oriented, multidisciplinary, distributed framework using the Adaptive Modeling Language (AML) as a framework and supporting the configuration design and parametric CFD grid generation. This report will focus on describing the work in the area of parametric CFD grid generation using novel concepts for defining the interaction between the mesh topology and the geometry in such a way as to separate the mesh topology from the geometric topology while maintaining the link between the mesh topology and the actual geometry.

  14. New hardware and workflows for semi-automated correlative cryo-fluorescence and cryo-electron microscopy/tomography

    OpenAIRE

    Schorb, Martin; Gaechter, Leander; Avinoam, Ori; Sieckmann, Frank; Clarke, Mairi; Bebeacua, Cecilia; Bykov, Yury S.; Sonnen, Andreas F.-P.; Lihl, Reinhard; John A G Briggs

    2017-01-01

    Correlative light and electron microscopy allows features of interest defined by fluorescence signals to be located in an electron micrograph of the same sample. Rare dynamic events or specific objects can be identified, targeted and imaged by electron microscopy or tomography. To combine it with structural studies using cryo-electron microscopy or tomography, fluorescence microscopy must be performed while maintaining the specimen vitrified at liquid-nitrogen temperatures and in a dry enviro...

  15. Computer Aided Design Tools for Extreme Environment Electronics Project

    Data.gov (United States)

    National Aeronautics and Space Administration — This project aims to provide Computer Aided Design (CAD) tools for radiation-tolerant, wide-temperature-range digital, analog, mixed-signal, and radio-frequency...

  16. CloneAssistant 1.0: a stand-alone software for automated cloning primer design.

    Science.gov (United States)

    Shao, Chaogang; Meng, Yijun; Lv, Shaolei; Zhong, Wei; Wang, Zheyu; Chen, Ming

    2010-11-01

    "CloneAssistant 1.0" is a stand-alone software compatible with the current Windows operating systems, which can automatically design cloning primers with full consideration of the sequence information of vectors and genes, cloning strategies, the principles of primer design, reading frames, position effects, and enzymatic reaction conditions for users. Five internal XML (extensible markup language) databases [restriction enzymes, plasmids, universal buffers, PCR (polymerase chain reaction) protection bases, and an MCS (multiple cloning site) double digest interference database] were established to serve as the basic support for "CloneAssistant 1.0". The primer pairs designed are sorted according to the difficulty of the follow-up experiments. Once a primer pair is selected by the user, detailed experimental guidance for this primer pair will be provided. In addition, "CloneAssistant 1.0" can be used for restriction map analysis, ORF (open reading frame) finding, sequence alignment and complementary analysis, translation, restriction enzyme and universal buffer queries, and isocaudamer analysis. "CloneAssistant 1.0" makes gene clone design much easier, and it can be freely downloaded from http://bis.zju.edu.cn/clone. Copyright © 2010 Elsevier B.V. All rights reserved.

  17. HiVy automated translation of stateflow designs for model checking verification

    Science.gov (United States)

    Pingree, Paula

    2003-01-01

    tool set enables model checking of finite state machines designs. This is acheived by translating state-chart specifications into the input language of the Spin model checker. An abstract syntax of hierarchical sequential automata (HSA) is provided as an intermediate format tool set.

  18. Designing Automated Adaptive Support to Improve Student Helping Behaviors in a Peer Tutoring Activity

    Science.gov (United States)

    Walker, Erin; Rummel, Nikol; Koedinger, Kenneth R.

    2011-01-01

    Adaptive collaborative learning support systems analyze student collaboration as it occurs and provide targeted assistance to the collaborators. Too little is known about how to design adaptive support to have a positive effect on interaction and learning. We investigated this problem in a reciprocal peer tutoring scenario, where two students take…

  19. Iterative Design and Classroom Evaluation of Automated Formative Feedback for Improving Peer Feedback Localization

    Science.gov (United States)

    Nguyen, Huy; Xiong, Wenting; Litman, Diane

    2017-01-01

    A peer-review system that automatically evaluates and provides formative feedback on free-text feedback comments of students was iteratively designed and evaluated in college and high-school classrooms. Classroom assignments required students to write paper drafts and submit them to a peer-review system. When student peers later submitted feedback…

  20. Conceptual Design Automation : Abstraction complexity reduction by feasilisation and knowledge engineering

    NARCIS (Netherlands)

    Schut, E.J.

    2010-01-01

    In order to keep innovating, engineers are working more and more with engineering software, providing them a way to cut away their routine and repetitive activities. Computer aided design and simulation software are for instance considered standard tools in most engineering companies. Today, to

  1. Overview of software products for the terrain analysis in the tasks of design automation of wind-power stations

    Directory of Open Access Journals (Sweden)

    Volkov Andrey Anatol’evich

    2014-03-01

    Full Text Available The lack of ground and constantly growing price for energy sources are the reason for using alternative energy. The rules of the world community for environmental protection is the motivation for using renewable energy sources. It is necessary to automate the processes of the design technology for the alternative energy structures and their operation, as well as data gathering and analisys on all the existing objects. There is also the need to automise these objects' management. The topic of this article is connected to the analysis of terrain for designing windpower stations. The regional wind maps are valuable tools for the wind farm developer for searching site, but they are not accurate enough to justify the financing of the development. For the majority of prospective wind farms, the developer must undertake a wind resource measurement and use analyzing program. This should provide a robust prediction of the expected energy production over its lifetime. The authors note that a prediction of the energy production of a wind farm is possible using such methods as the wind atlas methodology within WAsP and show the main instruments.

  2. [Automated anesthesia record systems].

    Science.gov (United States)

    Heinrichs, W; Mönk, S; Eberle, B

    1997-07-01

    The introduction of electronic anaesthesia documentation systems was attempted as early as in 1979, although their efficient application has become reality only in the past few years. The advantages of the electronic protocol are apparent: Continuous high quality documentation, comparability of data due to the availability of a data bank, reduction in the workload of the anaesthetist and availability of additional data. Disadvantages of the electronic protocol have also been discussed in the literature. By going through the process of entering data on the course of the anaesthetic procedure on the protocol sheet, the information is mentally absorbed and evaluated by the anaesthetist. This information may, however, be lost when the data are recorded fully automatically-without active involvement on the part of the anaesthetist. Recent publications state that by using intelligent alarms and/or integrated displays manual record keeping is no longer necessary for anaesthesia vigilance. The technical design of automated anaesthesia records depends on an integration of network technology into the hospital. It will be appropriate to connect the systems to the internet, but safety requirements have to be followed strictly. Concerning the database, client server architecture as well as language standards like SQL should be used. Object oriented databases will be available in the near future. Another future goal of automated anaesthesia record systems will be using knowledge based technologies within these systems. Drug interactions, disease related anaesthetic techniques and other information sources can be integrated. At this time, almost none of the commercially available systems has matured to a point where their purchase can be recommended without reservation. There is still a lack of standards for the subsequent exchange of data and a solution to a number of ergonomic problems still remains to be found. Nevertheless, electronic anaesthesia protocols will be required in

  3. FY1995 study of low power LSI design automation software with parallel processing; 1995 nendo heiretsu shori wo katsuyoshita shodenryoku LSI muke sekkei jidoka software no kenkyu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The needs for low power LSIs have rapidly increased recently. For the low power LSI development, not only new circuit technologies but also new design automation tools supporting the new technologies are indispensable. The purpose of this project is to develop a new design automation software, which is able to design new digital LSIs with much lower power than that of conventional CMOS LSIs. A new design automation software for very low power LSIs has been developed targeting the pass-transistor logic SPL, a dedicated low power circuit technology. The software includes a logic synthesis function for pass-transistor-based macrocells and a macrocell placement function. Several new algorithms have been developed for the software, e.g. BDD construction. Some of them are designed and implemented for parallel processing in order to reduce the processing time. The logic synthesis function was tested on a set of benchmarks and finally applied to a low power CPU design. The designed 8-bit CPU was fully compatible with Zilog Z-80. The power dissipation of the CPU was compared with that of commercial CMOS Z-80. At most 82% of power of CMOS was reduced by the new CPU. On the other hand, parallel processing speed up was measured on the macrocell placement function. 34 folds speed up was realized. (NEDO)

  4. Design and Implementation of the Automated Rendezvous Targeting Algorithms for Orion

    Science.gov (United States)

    DSouza, Christopher; Weeks, Michael

    2010-01-01

    The Orion vehicle will be designed to perform several rendezvous missions: rendezvous with the ISS in Low Earth Orbit (LEO), rendezvous with the EDS/Altair in LEO, a contingency rendezvous with the ascent stage of the Altair in Low Lunar Orbit (LLO) and a contingency rendezvous in LLO with the ascent and descent stage in the case of an aborted lunar landing. Therefore, it is not difficult to realize that each of these scenarios imposes different operational, timing, and performance constraints on the GNC system. To this end, a suite of on-board guidance and targeting algorithms have been designed to meet the requirement to perform the rendezvous independent of communications with the ground. This capability is particularly relevant for the lunar missions, some of which may occur on the far side of the moon. This paper will describe these algorithms which are designed to be structured and arranged in such a way so as to be flexible and able to safely perform a wide variety of rendezvous trajectories. The goal of the algorithms is not to merely fly one specific type of canned rendezvous profile. Conversely, it was designed from the start to be general enough such that any type of trajectory profile can be flown.(i.e. a coelliptic profile, a stable orbit rendezvous profile, and a expedited LLO rendezvous profile, etc) all using the same rendezvous suite of algorithms. Each of these profiles makes use of maneuver types which have been designed with dual goals of robustness and performance. They are designed to converge quickly under dispersed conditions and they are designed to perform many of the functions performed on the ground today. The targeting algorithms consist of a phasing maneuver (NC), an altitude adjust maneuver (NH), and plane change maneuver (NPC), a coelliptic maneuver (NSR), a Lambert targeted maneuver, and several multiple-burn targeted maneuvers which combine one of more of these algorithms. The derivation and implementation of each of these

  5. The automated multiparameter analyzer for cells (AMAC) IIA, a true bridge circuit Coulter-type electronic cell volume transducer.

    Science.gov (United States)

    Leif, R C; Guarino, V; Lefkove, N

    1979-01-01

    A true bridge Coulter effect (electronic cell volume) transducer has been developed. All resistances of this bridge are now the result of current flow through saline channels. Contamination by electrode products including gas bubbles has been completely eliminated since both power electrodes are now remote from the flow chamber. Since the orifice is in series with an approximately 10 K ohm resistance generated by a gel-filled capillary and a displacement rheostat, it floats electrically, at virtual ground. The other side of the bridge consists of a fluid side-wire. Removing the power electrode from the orifice outlet makes possible downward flow and the use of a single outer sheath, and eliminates noise generated by gas bubbles which could possibly be trapped. It should now be possible to combine this design with that of the AMAC III square orifice, to produce an electro-optical sorter where all parameters are measured simultaneously. This true bridge circuit possesses the further advantage that noise due both to the power supply and to overvoltage at the power electrodes is common-mode rejected, and any drift due to changes in electrode polarization is eliminated. Preliminary experiments confirm results with the AMAC II that hemoglobinopathies can be recognized by the increased coefficient of variation (CV) of the erythrocyte spectra.

  6. An automation of design and modelling tasks in NX Siemens environment with original software - cost module

    Science.gov (United States)

    Zbiciak, R.; Grabowik, C.; Janik, W.

    2015-11-01

    The design-constructional process is a creation activity which strives to fulfil, as well as it possible at the certain moment of time, all demands and needs formulated by a user taking into account social, technical and technological advances. Engineer knowledge and skills and their inborn abilities have the greatest influence on the final product quality and cost. They have also deciding influence on product technical and economic value. Taking into account above it seems to be advisable to make software tools that support an engineer in the process of manufacturing cost estimation. The Cost module is built with analytical procedures which are used for relative manufacturing cost estimation. As in the case of the Generator module the Cost module was written in object programming language C# in Visual Studio environment. During the research the following eight factors, that have the greatest influence on overall manufacturing cost, were distinguished and defined: (i) a gear wheel teeth type it is straight or helicoidal, (ii) a gear wheel design shape A, B with or without wheel hub, (iii) a gear tooth module, (iv) teeth number, (v) gear rim width, (vi) gear wheel material, (vii) heat treatment or thermochemical treatment, (viii) accuracy class. Knowledge of parameters (i) to (v) is indispensable for proper modelling of 3D gear wheels models in CAD system environment. These parameters are also processed in the Cost module. The last three parameters it is (vi) to (viii) are exclusively used in the Cost module. The estimation of manufacturing relative cost is based on indexes calculated for each particular parameter. Estimated in this way the manufacturing relative cost gives an overview of design parameters influence on the final gear wheel manufacturing cost. This relative manufacturing cost takes values from 0.00 to 1,00 range. The bigger index value the higher relative manufacturing cost is. Verification whether the proposed algorithm of relative manufacturing

  7. Towards product design automation based on parameterized standard model with diversiform knowledge

    Science.gov (United States)

    Liu, Wei; Zhang, Xiaobing

    2017-04-01

    Product standardization based on CAD software is an effective way to improve design efficiency. In the past, research and development on standardization mainly focused on the level of component, and the standardization of the entire product as a whole is rarely taken into consideration. In this paper, the size and structure of 3D product models are both driven by the Excel datasheets, based on which a parameterized model library is therefore established. Diversiform knowledge including associated parameters and default properties are embedded into the templates in advance to simplify their reuse. Through the simple operation, we can obtain the correct product with the finished 3D models including single parts or complex assemblies. Two examples are illustrated later to invalid the idea, which will greatly improve the design efficiency.

  8. Automated array assembly. Quarterly report No. 5. [Cost analysis and factory design

    Energy Technology Data Exchange (ETDEWEB)

    D' Aiello, R.V.

    1977-10-01

    During this quarter, an interim 1982 factory was designed for the large-scale production of silicon solar cell array modules. The boundary conditions for this design are the use of Czochralski silicon crystals and $25/kg polycrystalline silicon. The objective is a large-scale production facility to meet an intermediate ERDA cost goal of $2.00/W in 1982. The approach was to first consider a panel design which could be expected to have a 20-year life and would also meet the JPL specification on mechanical, electrical, and environmental stability. Attention was then directed to a cost analysis of the production of the elements comprising this panel. Since it was expected that wafer production would comprise a major fraction of the cost, several cost reduction schemes were considered for the Czochralski pulling and sawing of the wafers. A solar-cell processing sequence was selected on the basis of our previous cost studies and the projected availability of production equipment by 1982. These criteria resulted in the selection of POCl/sub 3/ gaseous diffusion for junction formation, thick-film Ag screen-printed metallization, spray-on antireflection (AR) coating, and solder reflow interconnect technology. The economic study was made by computer analysis of the cost elements of these process sequences at production levels ranging from 3 to 100 MW/yr. With the results of this study, a 30-MW/yr factory was designed, and a preliminary floor plan layout is given. A manufacturing cost of $2.01/W is projected and, including factory overhead and profit, a selling price of $2.27/W is projected.

  9. The Conceptual Design of an Automated Mobilization/Management Information System,

    Science.gov (United States)

    1985-09-01

    the Operations Research and Economic Analysis Office (DLA-LO) model the DLA logistical operations and design an information processing and analysis...disciplines. The first applicable dicipline for this project is Boolean Algebra This mathematical logic is used to translate a language texts...describing an operation or function,.into an objective set of symbolsand equations. Solving these equations produces a non.redundant, symbolic system which

  10. Wireless Communication Electronics Introduction to RF Circuits and Design Techniques

    CERN Document Server

    Sobot, Robert

    2012-01-01

    This book is intended for senior undergraduate and graduate students as well as practicing engineers who are involved in design and analysis of radio frequency (RF) circuits.  Detailed tutorials are included on all major topics required to understand fundamental principles behind both the main sub-circuits required to design an RF transceiver and the whole communication system. Starting with review of fundamental principles in electromagnetic (EM) transmission and signal propagation, through detailed practical analysis of RF amplifier, mixer, modulator, demodulator, and oscillator circuit topologies, all the way to the system communication theory behind the RF transceiver operation, this book systematically covers all relevant aspects in a way that is suitable for a single semester university level course.   Offers readers a complete, self-sufficient tutorial style textbook; Includes all relevant topics required to study and design an RF receiver in a consistent, coherent way with appropriate depth for a on...

  11. QUALITY IMPROVEMENT THROUGH AUTOMATION OF PRODUCT DESIGN PROCESS IN A MANUFACTURING ORGANIZATION

    Directory of Open Access Journals (Sweden)

    M.T. Sawant

    2012-03-01

    Full Text Available This paper focuses on the use of CAE for improving some of the quality dimensions of the business process, such as reliability and quick response to market. To establish this, a software based approach is developed coupled with interface with CAD environment by using RAD technology. This system would help enable the rapid design and generation of model of a critical component like the rotor of a submersible pump. The parametric design of the critical component i.e. mo tor is established and software solution for the same is developed. The dimensions of the rotor are critical and interdependent. The flexibility thus obtained using the software will facilitate fast design of a submersible pump. This case study has been carried at M/s. Vira Pumps, Kolhapur, India. The company manufactures and exports different types of submersible pumps and motors to many countries. The company is working in this area from last 35 years. Being an ISO 9001 certified company there is an on going continual improvement process in all its areas of operation. ISO 9001:2008 specifies requirements for a quality management system where an organization needs to demonstrate its ability to consistently provide product that meets customer requirements, and aims to enhance customer satisfaction through the quick reply and improved reliability of the product with CAE.

  12. Functional Design of an Automated Instructional Support System for Operational Flight Trainers. Final Report, June 1976 through September 1977.

    Science.gov (United States)

    Semple, Clarence A.; And Others

    Functional requirements for a highly automated, flexible, instructional support system for aircrew training simulators are presented. Automated support modes and associated features and capabilities are described, along with hardware and software functional requirements for implementing a baseline system in an operational flight training context.…

  13. Design and Analysis of an Electron Gun/Booster and Free Electron Laser Optical Theory

    Science.gov (United States)

    2010-09-01

    gas ( TIG ) welding has been poor [12]. Electron beam welding offers a much more controllable environment for ensuring weld quality and minimizing...beam welding of the NPS cavity . . . . . . . . . . . . . . . . . 54 29. Buffered chemical polish station . . . . . . . . . . . . . . . . . . . . . . 55...degree turn (and weld ) and to improve the ability to clean the cavities. Removing surface contaminants is of utmost importance in superconducting

  14. Electronic system level design an open-source approach

    CERN Document Server

    Rigo, Sandro; Santos, Luiz

    2014-01-01

    This book devises ESL design from the pragmatic perspective of a SystemC-based representation by showing how to build and how to use ESL languages, models and tools. It includes TLM 2.0 and step-by-step examples; it also addresses power modeling.

  15. Electronic-Structure-Based Design of Ordered Alloys

    DEFF Research Database (Denmark)

    Bligaard, Thomas; Andersson, M.P.; Jacobsen, Karsten Wedel

    2006-01-01

    design of other materials as well. A central problem is how to treat the huge number of compounds that can be envisioned by varying the concentrations and the number of the elements involved. We discuss various strategies for approaching this problem and show how one strategy has led to the computational...

  16. Towards automated consulting: Design feedback from the performance of online documentation

    Energy Technology Data Exchange (ETDEWEB)

    Girill, T.R.; Luk, C.H.; Norton, S.

    1987-07-01

    Usage monitoring of online documentation at a supercomputer center strongly suggests the importance of three strategies in the design of an effective ''consulting'' system to deliver full-text answer passages to end users: (1) persistent on-demand printing as well as online viewing make a shared database economically vital; (2) a broad range of subject queries makes retrieval on diverse topics through a single user interface psychologically beneficial to readers, and (3) vocabulary mismatch errors demand an active response to faulty search terms, but not at the cost of increased interface complexity.

  17. Physics Design Considerations for Diagnostic X Electron Beam Transport System

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Y-J

    2000-04-10

    The Diagnostic X (D-X) beamlines will transport the DARHT-II beam from the end of the accelerator to the Diagnostic X firing point providing four lines of sight for x-ray radiography. The design goal for the Diagnostic X beamline is to deliver four x-ray pulses with the DARHT-II dose format and time integrated spot size on each line of sight. The D-X beamline's final focus should be compatible with a range of first conjugates from 1 m-5 m. Furthermore, the D-X beamline operational parameters and the beamline layout should not preclude a possible upgrade to additional lines of sight. The DARHT-II accelerator is designed to deliver beams at a rate of 1 pulse per minute or less. Tuning the D-X beamline with several hundred optical elements would be time consuming. Therefore, minimizing the required number of tuning shots for the D-X beamline is also an important design goal. Many different beamline configurations may be able to accomplish these design objectives, and high beam quality (i.e., high current and low emittance) must be maintained throughout the chosen beamline configuration in order to achieve the DARHT-II x-ray dose format. In general, the longer the distance a beam travels, the harder it is to preserve the beam quality. Therefore, from the point of view of maintaining beam quality, it is highly desirable to minimize the beamline length. Lastly, modification to the DARHT-II building and the downstream transport should be minimized. Several processes can degrade beam quality by increasing the beam emittance, increasing the time-varying transverse beam motion, creating a beam halo, or creating a time-varying beam envelope. In this report, we consider those processes in the passive magnet lattice beamline and indicate how they constrain the beamline design. The physics design considerations for the active components such as the kicker system will be discussed in Ref. 2. In Sec. I, we discuss how beam emittance affects the x-ray forward dose. We also

  18. ELECTRON BEAM ION SOURCE PREINJECTOR PROJECT (EBIS) CONCEPTUAL DESIGN REPORT.

    Energy Technology Data Exchange (ETDEWEB)

    ALESSI, J.; BARTON, D.; BEEBE, E.; GASSNER, D.; ET AL.

    2005-02-28

    This report describes a new heavy ion pre-injector for the Relativistic Heavy Ion Collider (RHIC) based on a high charge state Electron Beam Ion Source (EBIS), a Radio Frequency Quadrupole (RFQ) accelerator, and a short Linac. The highly successful development of an EBIS at BNL now makes it possible to replace the present pre-injector that is based on an electrostatic Tandem with a reliable, low maintenance Linac-based pre-injector. Linac-based pre-injectors are presently used at most accelerator and collider facilities with the exception of RHIC, where the required gold beam intensities could only be met with a Tandem until the recent EBIS development. EBIS produces high charge state ions directly, eliminating the need for the two stripping foils presently used with the Tandem. Unstable stripping efficiencies of these foils are a significant source of luminosity degradation in RHIC. The high reliability and flexibility of the new Linac-based pre-injector will lead to increased integrated luminosity at RHIC and is an essential component for the long-term success of the RHIC facility. This new pre-injector, based on an EBIS, also has the potential for significant future intensity increases and can produce heavy ion beams of all species including uranium beams and, as part of a future upgrade, might also be used to produce polarized {sup 3}He beams. These capabilities will be critical to the future luminosity upgrades and electron-ion collisions in RHIC. The new RFQ and Linac that are used to accelerate beams from the EBIS to an energy sufficient for injection into the Booster are both very similar to existing devices already in operation at other facilities. Injection into the Booster will occur at the same location as the existing injection from the Tandem.

  19. INTAMAP: The design and implementation of an interoperable automated interpolation web service

    Science.gov (United States)

    Pebesma, Edzer; Cornford, Dan; Dubois, Gregoire; Heuvelink, Gerard B. M.; Hristopulos, Dionisis; Pilz, Jürgen; Stöhlker, Ulrich; Morin, Gary; Skøien, Jon O.

    2011-03-01

    INTAMAP is a Web Processing Service for the automatic spatial interpolation of measured point data. Requirements were (i) using open standards for spatial data such as developed in the context of the Open Geospatial Consortium (OGC), (ii) using a suitable environment for statistical modelling and computation, and (iii) producing an integrated, open source solution. The system couples an open-source Web Processing Service (developed by 52°North), accepting data in the form of standardised XML documents (conforming to the OGC Observations and Measurements standard) with a computing back-end realised in the R statistical environment. The probability distribution of interpolation errors is encoded with UncertML, a markup language designed to encode uncertain data. Automatic interpolation needs to be useful for a wide range of applications and the algorithms have been designed to cope with anisotropy, extreme values, and data with known error distributions. Besides a fully automatic mode, the system can be used with different levels of user control over the interpolation process.

  20. Automated Design of Synthetic Cell Classifier Circuits Using a Two-Step Optimization Strategy.

    Science.gov (United States)

    Mohammadi, Pejman; Beerenwinkel, Niko; Benenson, Yaakov

    2017-02-22

    Cell classifiers are genetic logic circuits that transduce endogenous molecular inputs into cell-type-specific responses. Designing classifiers that achieve optimal differential response between specific cell types is a hard computational problem because it involves selection of endogenous inputs and optimization of both biochemical parameters and a logic function. To address this problem, we first derive an optimal set of biochemical parameters with the largest expected differential response over a diverse set of logic circuits, and second, we use these parameters in an evolutionary algorithm to select circuit inputs and optimize the logic function. Using this approach, we design experimentally feasible microRNA-based circuits capable of perfect discrimination for several real-world cell-classification tasks. We also find that under realistic cell-to-cell variation, circuit performance is comparable to standard cross-validation performance estimates. Our approach facilitates the generation of candidate circuits for experimental testing in therapeutic settings that require precise cell targeting, such as cancer therapy. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Automation in Warehouse Development

    CERN Document Server

    Verriet, Jacques

    2012-01-01

    The warehouses of the future will come in a variety of forms, but with a few common ingredients. Firstly, human operational handling of items in warehouses is increasingly being replaced by automated item handling. Extended warehouse automation counteracts the scarcity of human operators and supports the quality of picking processes. Secondly, the development of models to simulate and analyse warehouse designs and their components facilitates the challenging task of developing warehouses that take into account each customer’s individual requirements and logistic processes. Automation in Warehouse Development addresses both types of automation from the innovative perspective of applied science. In particular, it describes the outcomes of the Falcon project, a joint endeavour by a consortium of industrial and academic partners. The results include a model-based approach to automate warehouse control design, analysis models for warehouse design, concepts for robotic item handling and computer vision, and auton...

  2. Advanced Design Tools for the Lifetime of Power Electronics – Study Case on Motor Drive Application

    DEFF Research Database (Denmark)

    Ma, Ke; Vernica, Ionut; Blaabjerg, Frede

    2016-01-01

    electronics. In this paper, an advanced design tool structure, which can acquire various reliability metrics of the power electronics, is proposed. The proposed design tool is based on the failure mechanisms in the critical components of the power electronics, and the mission profiles in the converter......In many important energy conversion systems, the power electronic converters are proven to have high failure rates. At the same time, the failures of the power electronics systems are becoming more and more unacceptable because of the high cost of failures. As a consequence, an appropriate...... assessment of reliability performance for the power electronics is a crucial and emerging need, because it is the essential information for the reliability improvements, and thus reduction of the cost-of-energy. Unfortunately, there is still lack of suitable tools for the reliability assessment in power...

  3. Design of Electronic Experiments Using Computer Generated Virtual Instruments

    Science.gov (United States)

    1994-03-01

    is displayed on the front panel DC Voltage meter. C LABORATORY 4 DESIGN The original Laboratory 4, Transistor ( BJT ) Characteristics, experiment...voltage relations of an NPN transistor in a common-emitter circuit configuration used in both the static and dynamic operation. 5. Transistor curve...of a BJT common emitter amplifier to stated specifications, test it for prop biasing signal amplification characteristics and operational stability. 7

  4. Designing for Small Volume Assembly of Advanced Electronics Packages

    Science.gov (United States)

    Galbraith, L.; Bonner, J. K.

    1995-01-01

    We describe a general methodology to Design for Producibility and Reliability (DFPAR) for very small volume production runs. In cases where the entire volume for fabrication is less than five products, traditional Statistical Process Control (SPC) is inadequate due to reliance on statistics of much larger volumes and the Central Limit Theorem. Data acquisition for process parameter estimation from such a small sample size is difficult; however, it is critical to producing high reliability product.

  5. Design of an Indigenised Electronic Lock-In Amplifier

    Directory of Open Access Journals (Sweden)

    Umesh Kumar

    2000-01-01

    Full Text Available An indigenised lock-in amplifier is designed that enables the accurate measurement of signals contaminated by broad-band noise, power-line pick-up, frequency drift, or other sources of interference. It does this by means of an extremely narrow band detector which has the centre of its passband locked to the frequency of the signal to be measured. Large improvements in signal-to-noise ratio are achieved.

  6. Automated DNA Sequencing System

    Energy Technology Data Exchange (ETDEWEB)

    Armstrong, G.A.; Ekkebus, C.P.; Hauser, L.J.; Kress, R.L.; Mural, R.J.

    1999-04-25

    Oak Ridge National Laboratory (ORNL) is developing a core DNA sequencing facility to support biological research endeavors at ORNL and to conduct basic sequencing automation research. This facility is novel because its development is based on existing standard biology laboratory equipment; thus, the development process is of interest to the many small laboratories trying to use automation to control costs and increase throughput. Before automation, biology Laboratory personnel purified DNA, completed cycle sequencing, and prepared 96-well sample plates with commercially available hardware designed specifically for each step in the process. Following purification and thermal cycling, an automated sequencing machine was used for the sequencing. A technician handled all movement of the 96-well sample plates between machines. To automate the process, ORNL is adding a CRS Robotics A- 465 arm, ABI 377 sequencing machine, automated centrifuge, automated refrigerator, and possibly an automated SpeedVac. The entire system will be integrated with one central controller that will direct each machine and the robot. The goal of this system is to completely automate the sequencing procedure from bacterial cell samples through ready-to-be-sequenced DNA and ultimately to completed sequence. The system will be flexible and will accommodate different chemistries than existing automated sequencing lines. The system will be expanded in the future to include colony picking and/or actual sequencing. This discrete event, DNA sequencing system will demonstrate that smaller sequencing labs can achieve cost-effective the laboratory grow.

  7. ELECTRON BEAM ION SOURCE PREINJECTOR PROJECT (EBIS) CONCEPTUAL DESIGN REPORT.

    Energy Technology Data Exchange (ETDEWEB)

    ALESSI, J.; BARTON, D.; BEEBE, E.; GASSNER, D.; GRANDINETTI, R.; HSEUH, H.; JAVIDFAR, A.; KPONOU, A.; LAMBIASE, R.; LESSARD, E.; LOCKEY, R.; LODESTRO, V.; MAPES, M.; MIRABELLA, D.; NEHRING, T.; OERTER, B.; PENDZICK, A.; PIKIN, A.; RAPARIA, D.; RITTER, J.; ROSER, T.; RUSSO, T.; SNYDSTRUP, L.; WILINSKI, M.; ZALTSMAN, A.; ZHANG, S.

    2005-09-01

    This report describes a new heavy ion pre-injector for the Relativistic Heavy Ion Collider (RHIC) based on a high charge state Electron Beam Ion Source (EBIS), a Radio Frequency Quadrupole (RFQ) accelerator, and a short Linear accelerator (Linac). The highly successful development of an EBIS at Brookhaven National Laboratory (BNL) now makes it possible to replace the present pre-injector that is based on an electrostatic Tandem with a reliable, low maintenance Linac-based pre-injector. Linac-based preinjectors are presently used at most accelerator and collider facilities with the exception of RHIC, where the required gold beam intensities could only be met with a Tandem until the recent EBIS development. EBIS produces high charge state ions directly, eliminating the need for the two stripping foils presently used with the Tandem. Unstable stripping efficiencies of these foils are a significant source of luminosity degradation in RHIC. The high reliability and flexibility of the new Linac-based pre-injector will lead to increased integrated luminosity at RHIC and is an essential component for the long-term success of the RHIC facility. This new pre-injector, based on an EBIS, also has the potential for significant future intensity increases and can produce heavy ion beams of all species including uranium beams and, as part of a future upgrade, might also be used to produce polarized {sup 3}He beams. These capabilities will be critical to the future luminosity upgrades and electron-ion collisions in RHIC. The proposed pre-injector system would also provide for a major enhancement in capability for the NASA Space Radiation Laboratory (NSRL), which utilizes heavy-ion beams from the RHIC complex. EBIS would allow for the acceleration of all important ion species for the NASA radiobiology program, such as, helium, argon, and neon which are unavailable with the present Tandem injector. In addition, the new system would allow for very rapid switching of ion species for

  8. A Framework for Effective User Interface Design for Web-Based Electronic Commerce Applications

    Directory of Open Access Journals (Sweden)

    Justyna Burns

    2001-01-01

    Full Text Available Efficient delivery of relevant product information is increasingly becoming the central basis of competition between firms. The interface design represents the central component for successful information delivery to consumers. However, interface design for web-based information systems is probably more an art than a science at this point in time. Much research is needed to understand properties of an effective interface for electronic commerce. This paper develops a framework identifying the relationship between user factors, the role of the user interface and overall system success for web-based electronic commerce. The paper argues that web-based systems for electronic commerce have some similar properties to decision support systems (DSS and adapts an established DSS framework to the electronic commerce domain. Based on a limited amount of research studying web browser interface design, the framework identifies areas of research needed and outlines possible relationships between consumer characteristics, interface design attributes and measures of overall system success.

  9. Electronics Modeling and Design for Cryogenic and Radiation Hard Applications Project

    Data.gov (United States)

    National Aeronautics and Space Administration — We are developing CAD tools, models and methodologies for electronics design for circuit operation in extreme environments with a focus on very low temperature and...

  10. The Design and Construction of a Simple Transmission Electron Microscope for Educational Purposes.

    Science.gov (United States)

    Hearsey, Paul K.

    This document presents a model for a simple transmission electron microscope for educational purposes. This microscope could demonstrate thermonic emission, particle acceleration, electron deflection, and flourescence. It is designed to be used in high school science courses, particularly physics, taking into account the size, weight, complexity…

  11. Power Electronics Design Laboratory Exercise for Final-Year M.Sc. Students

    Science.gov (United States)

    Max, L.; Thiringer, T.; Undeland, T.; Karlsson, R.

    2009-01-01

    This paper presents experiences and results from a project task in power electronics for students at Chalmers University of Technology, Goteborg, Sweden, based on a flyback test board. The board is used in the course Power Electronic Devices and Applications. In the project task, the students design snubber circuits, improve the control of the…

  12. Recent progress in the design and clinical development of electronic-nose technologies

    Science.gov (United States)

    Dan Wilson

    2016-01-01

    Electronic-nose (e-nose) devices are instruments designed to detect and discriminate between precise complex gaseous mixtures of volatile organic compounds derived from specific organic sources, such as clinical test samples from patients, based on electronic aroma signature patterns (distinct digital sensor responses) resulting from the combined outputs of a...

  13. Design and performance of a 30 KV electron gun with ten independent cathodes & a magnetic lens.

    Energy Technology Data Exchange (ETDEWEB)

    Rudys, Joseph Matthew; Reed, Kim Warren

    2006-08-01

    Measurements on a 30 kV electron gun with ten independent cathodes, operating in a 6.5 Tesla (T) magnetic field are presented. An earlier paper covered the design of this electron gun [1]. Experimental results are compared to model predictions. Beam current is compared to theoretical space charge limited flow.

  14. Conceptual framework for the design and conception of an electronic trade platform in agribusiness

    OpenAIRE

    Hausen, Tobias; Helbig, Ralf; Schiefer, Gerhard

    2002-01-01

    This article gives an overview of a conceptual framework for the designing and implementation of an electronic trade platform. The trade platform prototype is the basis of a general conception for the design and implementation of internet-based trade platforms in agribusiness. The main platform focus related to the concept are to convert traditional business relationships and transactions into an electronic system. The conceptual framework provides clarification with regard to the benefit of ...

  15. Design, Synthesis, and Characterization of High Performance Polymer Electrolytes for Printed Electronics and Energy Storage

    Science.gov (United States)

    2016-03-31

    positioning has made high-performance, light-weight power sources of increasing importance to the US military. Polymer electrolyte membranes , which...AFRL-AFOSR-VA-TR-2016-0168 Design, Synthesis, and Characterization of High Performance Polymer Electrolytes for Printed Electronics and Energy...Sep 2015 4. TITLE AND SUBTITLE Design, Synthesis, and Characterization of High Performance Polymer Electrolytes for Printed Electronics and Energy

  16. Multiphysics simulation by design for electrical machines, power electronics and drives

    CERN Document Server

    Rosu, Marius; Lin, Dingsheng; Ionel, Dan M; Popescu, Mircea; Blaabjerg, Frede; Rallabandi, Vandana; Staton, David

    2018-01-01

    This book combines the knowledge of experts from both academia and the software industry to present theories of multiphysics simulation by design for electrical machines, power electronics, and drives. The comprehensive design approach described within supports new applications required by technologies sustaining high drive efficiency. The highlighted framework considers the electric machine at the heart of the entire electric drive. The book also emphasizes the simulation by design concept--a concept that frames the entire highlighted design methodology, which is described and illustrated by various advanced simulation technologies. Multiphysics Simulation by Design for Electrical Machines, Power Electronics and Drives begins with the basics of electrical machine design and manufacturing tolerances. It also discusses fundamental aspects of the state of the art design process and includes examples from industrial practice. It explains FEM-based analysis techniques for electrical machine design--providing deta...

  17. Design and construction of the first Iranian powerful industrial electron accelerator

    Directory of Open Access Journals (Sweden)

    AM Poursaleh

    2015-09-01

    Full Text Available In This paper we will introduce the process of design and manufacturing an electron accelerator with 10MeV energy and 100kW power as the first Iranian powerful industrial electron accelerator. This accelerator designed based on modeling of one of the most powerful industrial accelerator called Rhodotron. But the design of the accelerator in a way that can be localize by relying on domestic industries. So although it looks like a Rhodotron accelerator structure but has some different in design and manufacture of components, the results are satisfactory

  18. Design and Testing of Electronic Devices for Harsh Environments

    CERN Document Server

    Nico, Costantino

    This thesis reports an overview and the main results of the research activity carried out within the PhD programme in Information Engineering of the University of Pisa (2010-2012). The research activity has been focused on different fields, including Automotive and High Energy Physics experiments, according to a common denominator: the development of electroni c devices and systems operating in harsh environments. There are many applications that forc e the adoption of design methodologies and strategies focused on this type of envir onments: military, biom edical, automotive, industrial and space. The development of solutions fulfilling specific operational requirements, therefore represents an interesting field of research. The first research activity has been framed within the ATHENIS project, funded by the CORDIS Commission of the European Community, and aiming at the development of a System-on-Chip, a r egulator for alternators employed on vehicles, presenting both configurability an d t...

  19. New Automated and High-Throughput Quantitative Analysis of Urinary Ketones by Multifiber Exchange-Solid Phase Microextraction Coupled to Fast Gas Chromatography/Negative Chemical-Electron Ionization/Mass Spectrometry

    Science.gov (United States)

    Pacenti, Marco; Dugheri, Stefano; Traldi, Pietro; Degli Esposti, Filippo; Perchiazzi, Nicola; Franchi, Elena; Calamante, Massimo; Kikic, Ireneo; Alessi, Paolo; Bonacchi, Alice; Salvadori, Edoardo; Arcangeli, Giulio; Cupelli, Vincenzo

    2010-01-01

    The present research is focused on automation, miniaturization, and system interaction with high throughput for multiple and specific Direct Immersion-Solid Phase Microextraction/Fast Gas Chromatography analysis of the urinary ketones. The specific Mass Spectrometry instrumentation, capable of supporting such the automated changeover from Negative Chemical to Electron Ionization mode, as well as the automation of the preparation procedure by new device called MultiFiber Exchange, through change of the fibers, allowed a friendly use of mass spectrometry apparatus with a number of advantages including reduced analyst time and greater reproducibility (2.01–5.32%). The detection limits for the seven ketones were less than 0.004 mg/L. For an innovative powerful meaning in high-throughput routine, the generality of the structurally informative Mass Spectrometry fragmentation patterns together with the chromatographic separation and software automation are also investigated. PMID:20628512

  20. Design and Achievement of User Interface Automation Testing of Linux Based on Element Tree of DogTail

    National Research Council Canada - National Science Library

    Wen-Chao Yuan; Hong-Mei Zhu; Zi-Qian Sun

    2017-01-01

    .... In order to set free from fuzzy and repeated manual testing, and improve efficiency, this paper achieves automation testing of UI under Linux, and proposes a method to identify and test UI widgets...

  1. Design of High Luminosity Ring-Ring Electron- Light Ion Collider at CEBAF

    Energy Technology Data Exchange (ETDEWEB)

    Slawomir Bogacz; Antje Bruell; Jean Delayen; Yaroslav Derbenev; Rolf Ent; Joseph Grames; Andrew Hutton; Geoffrey Krafft; Rui Li; Nikolitsa Merminga; Benard Poelker; Bogdan Wojtsekhowski; Byung Yunn; Yuhong Zhang; C Montag

    2007-06-25

    Experimental studies of fundamental structure of nucleons require an electron-ion collider of a center-of-mass energy up to 90 GeV at luminosity up to 1035 cm-2s-1 with both beams polarized. A CEBAF-based collider of 9 GeV electrons/positrons and 225 GeV ions is envisioned to meet this science need and as a next step for CEBAF after the planned 12 GeV energy upgrade of the fixed target program. A ring-ring scheme of this collider developed recently takes advantage of the existing polarized electron CW beam from the CEBAF and a green-field design of an ion complex with electron cooling. We present a conceptual design and report design studies of this high-luminosity collider.

  2. Low energy electron generator design and depth dose prediction for micro-superficies tumors treatment purposes

    Science.gov (United States)

    Khorshidi, Abdollah; Rajaee, Azimeh; Ahmadinejad, Marjan; Ghoranneviss, Mahmood; Ettelaee, Mehdi

    2014-09-01

    We investigate deposited energy and linear energy transfer (LET) of low energy ejection electrons in air and water layers of a generator design via a plasma source. A structured model of a concave cold cathode electron generator was designed and simulated by using Monte Carlo n-particle version X 2.7.0 (MCNPX) code. A negative dc high voltage was applied to a concave cathode up to -12 kV to determine electron energy activity. Results determined that the geometric dimensions of field size toward the anode increased in relation to the angle of the conic beam, widening the accumulated bulks. The increased field size increased the anode current, which also resulted in an increase of electron energy, a reduction in LET, a stretched build-up area and a dose curve that shifted to a higher depth. The biological effect of low energy electron radiation can be increased with an increase of LET; as the depth dose decreased, the electron energy increased at the same time. The study of electron irradiation as a conic beam from an electron generator may provide an accurate investigation of the indirect effect of low energy electrons on bystander cells.

  3. Design aspects of an electrostatic electron cooler for low-energy RHIC operation

    Energy Technology Data Exchange (ETDEWEB)

    Fedotov, A.; Ben-Zvi, I.; Brodowski, J.; Chang, X.Y.; Gassner, D.; Hoff, L.; Kayran, D.; Kewisch, J.; Oerter, B.; Pendzick, A.; Tepikian, S.; Thieberger, P.; Prost, L.; Shemyakin, A.

    2011-03-28

    Electron cooling was proposed to increase the luminosity of the Relativistic Heavy Ion Collider (RHIC) operation for heavy ion beam energies below 10 GeV/nucleon. The electron cooling system needed should be able to deliver an electron beam of adequate quality in a wide range of electron beam energies (0.9-5 MeV). An option of using an electrostatic accelerator to produce electrons for cooling heavy ions in RHIC was evaluated in detail. In this paper, we describe the requirements and options which were considered in the design of such a cooler for RHIC, as well as the associated challenges. The expected luminosity improvement and limitations with such an electron cooling system are also discussed.

  4. Solid state photochemistry. Subpanel A-2(a): Design of molecular precursors for electronic materials

    Energy Technology Data Exchange (ETDEWEB)

    Wells, R.L. [Duke Univ., Durham, NC (United States)

    1996-09-01

    Recent achievements of synthetic chemistry in the field of electronic materials are presented in three categories; viz, precursor design for improved processing, new chemistry for selective growth, and new growth techniques. This is followed by a discussion of challenges and opportunities in two general areas designated as composition and structure, and growth and processing.

  5. Micromechanics and advanced designs for curved photodetector arrays in hemispherical electronic-eye cameras.

    Science.gov (United States)

    Shin, Gunchul; Jung, Inhwa; Malyarchuk, Viktor; Song, Jizhou; Wang, Shuodao; Ko, Heung Cho; Huang, Yonggang; Ha, Jeong Sook; Rogers, John A

    2010-04-09

    The fabrication of a hemispherical electronic-eye camera with optimized designs based upon micromechanical analysis is reported. The photodetector arrays combine layouts with multidevice tiles and extended, non-coplanar interconnects to improve the fill factor and deformability, respectively. Quantitative comparison to micromechanics analysis reveals the key features of these designs. Color images collected with working cameras demonstrate the utility of these approaches.

  6. Progress on the design of the polarized Medium-energy Electron Ion Collider at JLAB

    Energy Technology Data Exchange (ETDEWEB)

    Lin, F.; Bogacz, A.; Brindza, P.; Camsonne, A.; Daly, E.; Derbenev, Ya. S.; Douglas, D.; Ent, R.; Gaskell, D.; Geng, R.; Grames, J.; Guo, J.; Harwood, L.; Hutton, A.; Jordan, K.; Kimber, A.; Krafft, G.; Li, R.; Michalski, T.; Morozov, V. S.; Nadel-Turonski, P.; /Jefferson Lab /Argonne /DESY /Moscow , Inst. Phys. Tech., Dolgoprydny /Dubna, JINR /Northern Illinois U. /Old Doominion U. /Novosibirsk, GOO Zaryad /SLAC /Texas A-M

    2015-07-14

    The Medium-energy Electron Ion Collider (MEIC) at JLab is designed to provide high luminosity and high polarization needed to reach new frontiers in the exploration of nuclear structure. The luminosity, exceeding 1033 cm-2s-1 in a broad range of the center-of-mass (CM) energy and maximum luminosity above 1034 cm-2s-1, is achieved by high-rate collisions of short small-emittance low-charge bunches made possible by high-energy electron cooling of the ion beam and synchrotron radiation damping of the electron beam. The polarization of light ion species (p, d, 3He) can be easily preserved and manipulated due to the unique figure-8 shape of the collider rings. A fully consistent set of parameters have been developed considering the balance of machine performance, required technical development and cost. This paper reports recent progress on the MEIC accelerator design including electron and ion complexes, integrated interaction region design, figure-8-ring-based electron and ion polarization schemes, RF/SRF systems and ERL-based high-energy electron cooling. Luminosity performance is also presented for the MEIC baseline design.

  7. Automated sub-5 nm image registration in integrated correlative fluorescence and electron microscopy using cathodoluminescence pointers

    NARCIS (Netherlands)

    Haring, M.T.; Liv Hamarat, N.; Zonnevylle, A.C.; Narvaez Gonzalez, A.C.; Voortman, L.M.; Kruit, P.; Hoogenboom, J.P.

    2017-01-01

    In the biological sciences, data from fluorescence and electron microscopy is correlated to allow fluorescence biomolecule identification within the cellular ultrastructure and/or ultrastructural analysis following live-cell imaging. High-accuracy (sub-100 nm) image overlay requires the addition of

  8. Improving sensitivity of machine learning methods for automated case identification from free-text electronic medical records

    NARCIS (Netherlands)

    Z. Afzal (Zubair); M.J. Schuemie (Martijn); J.C. van Blijderveen (Nico); E.F. Sen (Fatma); M.C.J.M. Sturkenboom (Miriam); J.A. Kors (Jan)

    2013-01-01

    textabstractBackground: Distinguishing cases from non-cases in free-text electronic medical records is an important initial step in observational epidemiological studies, but manual record validation is time-consuming and cumbersome. We compared different approaches to develop an automatic case

  9. Design, construction and testing of a low-cost automated (68)Gallium-labeling synthesis unit for clinical use.

    Science.gov (United States)

    Heidari, Pedram; Szretter, Alicia; Rushford, Laura E; Stevens, Maria; Collier, Lee; Sore, Judit; Hooker, Jacob; Mahmood, Umar

    2016-01-01

    The interest in (68)Gallium labeled PET probes continues to increase around the world. Widespread use in Europe and Asia has led to great interest for use at numerous sites in the US. One barrier to entry is the cost of the automated synthesis units for relatively simple labeling procedures. We describe the construction and testing of a relatively low-cost automated (68)Ga-labeling unit for human-use. We provide a guide for construction, including part lists and synthesis timelists to facilitate local implementation. Such inexpensive systems could help increase use around the globe and in the US in particular by removing one of the barriers to greater widespread availability. The developed automated synthesis unit reproducibly synthesized (68)Ga-DOTATOC with average yield of 71 ± 8% and a radiochemical purity ≥ 95% in a synthesis time of 25 ± 1 minutes. Automated product yields are comparable to that of manual synthesis. We demonstrate in-house construction and use of a low-cost automated synthesis unit for labeling of DOTATOC and similar peptides with (68)Gallium.

  10. Complex of codes for computer-aided design of electron guns with grid control

    Science.gov (United States)

    Petrosyan, A. I.; Juravleva, V. D.; Penzyakov, V. V.; Rogovin, V. I.

    2003-03-01

    The computer-aided design of gridded electron guns on a basis of two, two and half and 3D mathematical models is carried out. The parameters of cathode-grid assembly (CGA) are calculated, synthesis and the trajectories analysis of ungridded gun, in which a control grid is supposed to be established, are realized. The trajectories analysis of a beam in CGA cells is fulfilled, the coordinates, velocites and charges of large particles on an exit from CGA cells are used for definition of the initial data for solving beam motion equations in the gridded electron gun and further in magnetic focusing system. Electron-optical systems with gridded electron gun, designed with the help of this complex of codes, do not require experimental correction and provide good current permeability in microwave tubes.

  11. Parallel power electronics filters in three-phase four-wire systems principle, control and design

    CERN Document Server

    Wong, Man-Chung; Lam, Chi-Seng

    2016-01-01

    This book describes parallel power electronic filters for 3-phase 4-wire systems, focusing on the control, design and system operation. It presents the basics of power-electronics techniques applied in power systems as well as the advanced techniques in controlling, implementing and designing parallel power electronics converters. The power-quality compensation has been achieved using active filters and hybrid filters, and circuit models, control principles and operational practice problems have been verified by principle study, simulation and experimental results. The state-of-the-art research findings were mainly developed by a team at the University of Macau. Offering background information and related novel techniques, this book is a valuable resource for electrical engineers and researchers wanting to work on energy saving using power-quality compensators or renewable energy power electronics systems. .

  12. A Wire Scanner Design for Electron Beam Profile Measurement in the Linac Coherent Light Source Undulator

    CERN Document Server

    Bailey, James L; Yang Bing Xin

    2005-01-01

    The Linac Coherent Light Source (LCLS), currently under design, requires beam diagnostic instruments between the magnets in the beam undulator section. Ten wire scanners are planned as one of the primary instruments to characterize electron beam properties. The development of these wire scanners presents several design challenges due to the need for high accuracy and resolution of the wire motion (3 microns tolerance, typical) and the high intensity of the beam (3400 A over an area of 30 micron rms radius). In this paper, we present the technical specification and design criteria for the scanners. We will also present the mechanical design of the UHV-compatible drive and its engineering analysis. Lastly, we present the wire card design and discuss associated thermal and mechanical issues originating from the highly intense x-ray and electron beams.

  13. The use of genre analysis in the design of electronic meeting systems

    Directory of Open Access Journals (Sweden)

    Pedro Antunes

    2006-01-01

    Full Text Available Introduction. Genre analysis is an approach to study communication patterns and thus it can be applied to the specific context of meetings. This research investigates the impact of genre analysis on the design of electronic meeting systems. Background. The primary goal of genre analysis is to understand how virtual communities use digital communication to collaborate. This knowledge is fundamental to inform IT design, particularly in areas where communication and informality are paramount. However, the research literature does not report any experiments where genre analysis has been used to inform electronic meeting system design. Problems. The paper tackles the following common problems found in current electronic meeting systems: (1 reduced organizational integration, neglecting many contextual cues and explaining factors necessary to make meeting outcomes usable within the organization; (2 lack of support to specific communities of users, stressing the dependency on a facilitator to configure and manage the technology; and (3 lack of support to meeting occurrences that span across long time periods. Conclusion. . The paper describes how genre analysis was used to develop electronic meeting systems for several organizations and meeting genres. It covers the complete design process, from genre elicitation to validation. The obtained results demonstrate that the genre approach produces electronic meeting systems focused on organizational integration, pre-configured to communities of users, supporting long-term usage and added organizational value.

  14. Embedded system for building automation

    OpenAIRE

    Rolih, Andrej

    2014-01-01

    Home automation is a fast developing field of computer science and electronics. Companies are offering many different products for home automation. Ranging anywhere from complete systems for building management and control, to simple smart lights that can be connected to the internet. These products offer the user greater living comfort and lower their expenses by reducing the energy usage. This thesis shows the development of a simple home automation system that focuses mainly on the enhance...

  15. High-Temperature Air-Cooled Power Electronics Thermal Design: Annual Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    Waye, Scot [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-08-01

    Power electronics that use high-temperature devices pose a challenge for thermal management. With the devices running at higher temperatures and having a smaller footprint, the heat fluxes increase from previous power electronic designs. This project overview presents an approach to examine and design thermal management strategies through cooling technologies to keep devices within temperature limits, dissipate the heat generated by the devices and protect electrical interconnects and other components for inverter, converter, and charger applications. This analysis, validation, and demonstration intends to take a multi-scale approach over the device, module, and system levels to reduce size, weight, and cost.

  16. Towards a methodology to identify design changes for urban transport infrastructure in the era of automated driving and vehicle sharing

    NARCIS (Netherlands)

    Ozturker, M.; Milakis, D.; van Arem, B.

    2016-01-01

    Automated driving and vehicle sharing are considered among the most influential concepts for future urban and transport systems. While research has so far examined impacts of these concepts on traffic and to some extent mobility, the question about potential implications for urban transport

  17. Human factors in the presentation of computer-generated information - Aspects of design and application in automated flight traffic

    Science.gov (United States)

    Roske-Hofstrand, Renate J.

    1990-01-01

    The man-machine interface and its influence on the characteristics of computer displays in automated air traffic is discussed. The graphical presentation of spatial relationships and the problems it poses for air traffic control, and the solution of such problems are addressed. Psychological factors involved in the man-machine interface are stressed.

  18. Mapping of arterial location for the design of automated identification and analysis algorithms in whole body MRA.

    Science.gov (United States)

    McCormick, Lynne; Weir-McCall, Jonathan; Gandy, Stephen; White, Richard; McNeil, Andrew; Trucco, Emanuele; Houston, J Graeme

    2015-01-01

    Technological and medical advances have led to the realisation of full body imaging, with systemic diagnostic approaches becoming increasingly more prevalent. In the imaging of atherosclerotic disease, contrast -enhanced whole-body MRA has been demonstrated to enable detection of stenosis with a high sensitivity and specificity. Characterization of the systemic cardiovascular disease burden has significant prognostic value. A whole-body acquisition does however generate a large volume of three-dimensional data and as such there are expected to be significant advantages in developing automated techniques for the analysis of these images. Improved radiological workflow, reduced analysis time and increased analytical standardization are expected to be among the benefits offered by this approach. As part of a process of automated software development this study aimed to collect and validate arterial location ground truth. The data will be used to inform the development of semi-automated vascular identity tools, and allow the potential for the further development of semi-automated anatomically informed cardiovascular disease analysis and reporting.

  19. Design and implementation of a fs-resolved transmission electron microscope based on thermionic gun technology

    Energy Technology Data Exchange (ETDEWEB)

    Piazza, L., E-mail: luca.piazza@epfl.ch [Laboratory for Ultrafast Microscopy and Electron Scattering (LUMES), ICMP, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne (Switzerland); Masiel, D.J. [Integrated Dynamic Electron Solutions, Inc., 455 Bolero Drive, Danville, CA 94526 (United States); LaGrange, T.; Reed, B.W. [Condensed Matter and Materials Division Physical and Life Sciences Directorate, Lawrence Livermore National Laboratory, P.O. Box 808, L-356, Livermore, CA 94550 (United States); Barwick, B. [Department of Physics, Trinity College, 300 Summit St., Hartford, CT 06106 (United States); Carbone, Fabrizio [Laboratory for Ultrafast Microscopy and Electron Scattering (LUMES), ICMP, Ecole Polytechnique Fédérale de Lausanne, CH-1015 Lausanne (Switzerland)

    2013-09-23

    Highlights: • We present the implementation of a femtosecond-resolved ultrafast TEM. • This is the first ultrafast TEM based on a thermionic gun geometry. • An additional condenser lens has been used to maximize the electron count. • We achieved a time resolution of about 300 fs and an energy resolution of 1 eV. - Abstract: In this paper, the design and implementation of a femtosecond-resolved ultrafast transmission electron microscope is presented, based on a thermionic gun geometry. Utilizing an additional magnetic lens between the electron acceleration and the nominal condenser lens system, a larger percentage of the electrons created at the cathode are delivered to the specimen without degrading temporal, spatial and energy resolution significantly, while at the same time maintaining the femtosecond temporal resolution. Using the photon-induced near field electron microscopy effect (PINEM) on silver nanowires the cross-correlation between the light and electron pulses was measured, showing the impact of the gun settings and initiating laser pulse duration on the electron bunch properties. Tuneable electron pulses between 300 fs and several ps can be obtained, and an overall energy resolution around 1 eV was achieved.

  20. Design and engineering of a man-made diffusive electron-transport protein.

    Science.gov (United States)

    Fry, Bryan A; Solomon, Lee A; Leslie Dutton, P; Moser, Christopher C

    2016-05-01

    Maquettes are man-made cofactor-binding oxidoreductases designed from first principles with minimal reference to natural protein sequences. Here we focus on water-soluble maquettes designed and engineered to perform diffusive electron transport of the kind typically carried out by cytochromes, ferredoxins and flavodoxins and other small proteins in photosynthetic and respiratory energy conversion and oxido-reductive metabolism. Our designs were tested by analysis of electron transfer between heme maquettes and the well-known natural electron transporter, cytochrome c. Electron-transfer kinetics were measured from seconds to milliseconds by stopped-flow, while sub-millisecond resolution was achieved through laser photolysis of the carbon monoxide maquette heme complex. These measurements demonstrate electron transfer from the maquette to cytochrome c, reproducing the timescales and charge complementarity modulation observed in natural systems. The ionic strength dependence of inter-protein electron transfer from 9.7×10(6) M(-1) s(-1) to 1.2×10(9) M(-1) s(-1) follows a simple Debye-Hückel model for attraction between +8 net charged oxidized cytochrome c and -19 net charged heme maquette, with no indication of significant protein dipole moment steering. Successfully recreating essential components of energy conversion and downstream metabolism in man-made proteins holds promise for in vivo clinical intervention and for the production of fuel or other industrial products. This article is part of a Special Issue entitled Biodesign for Bioenergetics--the design and engineering of electronic transfer cofactors, proteins and protein networks, edited by Ronald L. Koder and J.L. Ross Anderson. Copyright © 2015 Elsevier B.V. All rights reserved.