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Sample records for egidijus arauskis edvardas

  1. Novel aspects of pathogenesis and regeneration mechanisms in COPD

    Directory of Open Access Journals (Sweden)

    Bagdonas E

    2015-06-01

    Full Text Available Edvardas Bagdonas, Jovile Raudoniute, Ieva Bruzauskaite, Ruta Aldonyte State Research Institute Center for Innovative Medicine, Vilnius, Lithuania Abstract: Chronic obstructive pulmonary disease (COPD, a major cause of death and morbidity worldwide, is characterized by expiratory airflow limitation that is not fully reversible, deregulated chronic inflammation, and emphysematous destruction of the lungs. Despite the fact that COPD is a steadily growing global healthcare problem, the conventional therapies remain palliative, and regenerative approaches for disease management are not available yet. We aim to provide an overview of key reviews, experimental, and clinical studies addressing lung emphysema development and repair mechanisms published in the past decade. Novel aspects discussed herein include integral revision of the literature focused on lung microflora changes in COPD, autoimmune component of the disease, and environmental risk factors other than cigarette smoke. The time span of studies on COPD, including emphysema, chronic bronchitis, and asthmatic bronchitis, covers almost 200 years, and several crucial mechanisms of COPD pathogenesis are described and studied. However, we still lack the holistic understanding of COPD development and the exact picture of the time-course and interplay of the events during stable, exacerbated, corticosteroid-treated COPD states, and transitions in-between. Several generally recognized mechanisms will be discussed shortly herein, ie, unregulated inflammation, proteolysis/antiproteolysis imbalance, and destroyed repair mechanisms, while novel topics such as deviated microbiota, air pollutants-related damage, and autoimmune process within the lung tissue will be discussed more extensively. Considerable influx of new data from the clinic, in vivo and in vitro studies stimulate to search for novel concise explanation and holistic understanding of COPD nowadays. Keywords: dysbiosis in COPD, autoimmune

  2. Inhaled therapies in patients with moderate COPD in clinical practice: current thinking

    Directory of Open Access Journals (Sweden)

    Ariel A

    2017-12-01

    Full Text Available Amnon Ariel,1 Alan Altraja,2,3 Andrey Belevskiy,4 Piotr W Boros,5 Edvardas Danila,6 Matjaz Fležar,7 Vladimir Koblizek,8 Zvi G Fridlender,9 Kosta Kostov,10 Alvils Krams,11 Branislava Milenkovic,12 Attila Somfay,13 Ruzena Tkacova,14 Neven Tudoric,15 Ruxandra Ulmeanu,16 Arschang Valipour17 1Emek Medical Center, Clalit Healthcare Services, Afula, Israel; 2Department of Pulmonary Medicine, University of Tartu, 3Lung Clinic, Tartu University Hospital, Tartu, Estonia; 4Department of Pulmonology, Russian National Research Medical University, Moscow, Russia; 5Lung Pathophysiology Department, National TB and Lung Diseases Research Institute, Warsaw, Poland; 6Clinic of Infectious Chest Diseases, Dermatovenereology, and Allergology, Vilnius University, Centre of Pulmonology and Allergology, Vilnius University Hospital, Vilnius, Lithuania; 7University Clinic of Respiratory and Allergic Diseases, Golnik, Slovenia; 8Department of Pneumology, University Hospital, Hradec Králové, Czech Republic; 9Institute of Pulmonary Medicine, Hadassah Medical Center, Jerusalem, Israel; 10Clinic of Pulmonary Diseases, Military Medical Academy, Sofia, Bulgaria; 11Medical Faculty of Latvian University, Riga East University Hospital, Riga, Latvia; 12Clinic for Pulmonary Diseases, Clinical Centre of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 13Department of Pulmonology, University of Szeged, Deszk, Hungary; 14Department of Respiratory Medicine and Tuberculosis, Faculty of Medicine, PJ Safarik University, Košice, Slovakia; 15School of Medicine, Dubrava University Hospital, Zagreb, Croatia; 16Marius Nasta Institute of Pneumology, Bucharest, Romania; 17Department of Respiratory and Critical Care Medicine, Ludwig Boltzmann Institute for COPD and Respiratory Epidemiology, Vienna, Austria Abstract: COPD is a complex, heterogeneous condition. Even in the early clinical stages, COPD carries a significant burden, with breathlessness frequently leading

  3. Editorial. The Discourses of Consumer Society and Creative Class: Aspects of Media and Communications

    Directory of Open Access Journals (Sweden)

    Jovilė Barevičiūtė

    2015-07-01

    geidžiamą statusą visuomenėje. O čia ypač svarbus vaidmuo atitenka naujajai žiniasklaidai ir medijuotajai komunikacijai. Šiame žurnalo numeryje iš savo pasirinktų ir jiems įdomių perspektyvų straipsnių autoriai gvildena su medijų ir komunikacijos aspektais vienaip ar kitaip susijusias šiuolaikinių visuomenių – vartojančios ir kuriančios – problemas. Pirmoje dalyje gretinami ir lyginami du minėti – vartojimo ir kūrybos – visuomenių konceptai. To savo tekstuose imasi Agnieška Juzefovič ir Eglė Jaškūnienė, dėmesį sutelkdamos į tam tikrus kūrybos visuomenės aspektus. Ieva Mantė Valivonytė savo straipsnyje analizuoja vartojimo visuomenės problematiką, gilindamasi į mados ir asmens individualumo raiškos ypatumus. Antroje dalyje šiuolaikinių visuomenių problematika toliau tyrinėjama imantis naujųjų medijų ir apskritai technikos raidos refleksijų. To savo straipsniuose imasi Saulius Kanišauskas ir Algis Mickūnas – pirmasis autorius labiau apibendrintu žvilgsniu, o antrasis – konkretesnio teorinio tyrimo perspektyvoje. Trečia dalis organiškai pratęsia antrąją: joje plėtojami detalesni naujųjų medijų tyrinėjimai, jas interpretuojant kaip tam tikro socialinio poveikio ir galios priemones. Agnė Rimienė ir Vilmantė Liubinienė savo straipsnyje analizuoja televizijos įtaką religinei komunikacijai XXI a. visuomenėje, o Ieva Aurylaitė gilinasi į komunikacinio galios diskurso apimtį ir ribas. Paskutinėje, ketvirtoje, dalyje plėtojamos filosofinės įžvalgos šio numerio tema. Jų savo straipsniuose imasi du autoriai – Edvardas Rimkus, labiau susitelkdamas į pažinimo aspektą, ir Seungbae Parkas, daugiau dėmesio skirdamas patyrimo problemai. Tikimasi, kad šis žurnalo numeris veiksmingai prisidės prie Vilniaus Gedimino technikos universiteto Kūrybinių industrijų fakulteto ir kitų Lietuvos bei užsienio universitetų mokslininkų produktyvesnio dialogo skatinimo.

  4. EDITORIAL: Focus on Cold and Ultracold Molecules FOCUS ON COLD AND ULTRACOLD MOLECULES

    Science.gov (United States)

    Carr, Lincoln D.; Ye, Jun

    2009-05-01

    Robin Côté Single-photon molecular cooling Edvardas Narevicius, S Travis Bannerman and Mark G Raizen Quantum simulations of extended Hubbard models with dipolar crystals M Ortner, A Micheli, G Pupillo and P Zoller Collisional and molecular spectroscopy in an ultracold Bose-Bose mixture G Thalhammer, G Barontini, J Catani, F Rabatti, C Weber, A Simoni, F Minardi and M Inguscio Multi-channel modelling of the formation of vibrationally cold polar KRb molecules Svetlana Kotochigova, Eite Tiesinga and Paul S Julienne Formation of ultracold, highly polar X1Σ+ NaCs molecules C Haimberger, J Kleinert, P Zabawa, A Wakim and N P Bigelow Quantum polarization spectroscopy of correlations in attractive fermionic gases T Roscilde, M Rodríguez, K Eckert, O Romero-Isart, M Lewenstein, E Polzik and A Sanpera Inelastic semiclassical collisions in cold dipolar gases Michael Cavagnero and Catherine Newell Quasi-universal dipolar scattering in cold and ultracold gases J L Bohn, M Cavagnero and C Ticknor Stark deceleration of lithium hydride molecules S K Tokunaga, J M Dyne, E A Hinds and M R Tarbutt Molecular vibrational cooling by optical pumping with shaped femtosecond pulses D Sofikitis, S Weber, A Fioretti, R Horchani, M Allegrini, B Chatel, D Comparat and P Pillet Deeply bound ultracold molecules in an optical lattice Johann G Danzl, Manfred J Mark, Elmar Haller, Mattias Gustavsson, Russell Hart, Andreas Liem, Holger Zellmer and Hanns-Christoph Nägerl Toward the production of quantum degenerate bosonic polar molecules, 41K87Rb K Aikawa, D Akamatsu, J Kobayashi, M Ueda, T Kishimoto and S Inouye Influence of a Feshbach resonance on the photoassociation of LiCs J Deiglmayr, P Pellegrini, A Grochola, M Repp, R Côté, O Dulieu, R Wester and M Weidemüller The kinematic cooling of molecules with laser-cooled atoms Ken Takase, Larry A Rahn, David W Chandler and Kevin E Strecker Coherent collapses of dipolar Bose-Einstein condensates for different trap geometries J Metz, T Lahaye, B Fr