WorldWideScience

Sample records for ege johanson merje

  1. EGEE helping bridge digital divide EGEE'06 Conference preview

    CERN Multimedia

    2006-01-01

    "In this GRIDtoday Q&A, EGEE project director Bob Jones discusses where EGEEE began and where it is now as the project enters the EGEE II era. In addition, Jones previews the EGEE'06 conference, which kicks off Sept. 25 in Geneva, Switzerland, and features for the first time a prominent businee track." (2 pages)

  2. Evaluating the Johanson theory for titanium powder

    CSIR Research Space (South Africa)

    Chikosha, S

    2015-05-01

    Full Text Available . In this study, the Johanson theory was used to determine the rolling parameters of titanium powder. Preliminary results of the nip angle, nip pressures and maximum horizontal pressures of the mill for the powder rolled on a 55mm diameter roll with roll gap sizes...

  3. Using EGEE against avian flu

    CERN Multimedia

    2006-01-01

    During April 2006 avian flu was spreading across the world with the potential of turning into a pandemic, a drug to treat the deadly H5N1 strain was needed. Such a task required the huge processing power provided by EGEE, which analysed 300 000 possible drug components for their suitability. This map shows the network of computer centres and their activity during this time.

  4. Tretjakova, Alavainu ja Johanson tuuritavad Ida-Virumaal

    Index Scriptorium Estoniae

    2004-01-01

    5. apr. alustavad turneed Ida-Virumaal Ave Alavainu ja Tatjana Tretjakova, et esitleda oma luuleraamatut "2keelsed = 2jazõtshnõje" (Kärdla : A. Alavainu, 2004). Jaak Johanson laulab laule nimetatud autorite tekstidele

  5. Encrypted Data Storage in EGEE

    CERN Document Server

    Frohner, Ákos

    2006-01-01

    The medical community is routinely using clinical images and associated medical data for diagnosis, intervention planning and therapy follow-up. Medical imaging is producing an increasing number of digital images for which computerized archiving, processing and analysis are needed. Grids are promising infrastructures for managing and analyzing the huge medical databases. Given the sensitive nature of medical images, practiotionners are often reluctant to use distributed systems though. Security if often implemented by isolating the imaging network from the outside world inside hospitals. Given the wide scale distribution of grid infrastructures and their multiple administrative entities, the level of security for manipulating medical data should be particularly high. In this presentation we describe the architecture of a solution, the gLite Encrypted Data Storage (EDS), which was developed in the framework of Enabling Grids for E-sciencE (EGEE), a project of the European Commission (contract number INFSO--508...

  6. European view of the EGEE infrastructure

    CERN Multimedia

    2007-01-01

    This view is of the Enabling Grids for E-sciencE (EGEE) infrastructure zoomed in on Europe. The EGEE allows the processing power of many computers to be shared so that the huge amount of data produced at CERN's new collider, the Large Hadron Collider (LHC) can be processed. The sites used in the Grid can be downloaded in a zipped .kmz format, which can be imported into Google Earth.

  7. World view of the EGEE infrastrucutre

    CERN Multimedia

    2007-01-01

    This view is of the Enabling Grids for E-sciencE (EGEE) project seen on the world scale. The EGEE allows the processing power of many computers to be shared so that the huge amount of data produced at CERN's new collider, the Large Hadron Collider (LHC) can be processed. The sites used in the Grid can be downloaded in a zipped .kmz format, which can be imported into Google Earth.

  8. Johanson-Blizzard syndrome: dental findings and management.

    Science.gov (United States)

    Santhosh, B P; Jethmalani, Preeti

    2013-05-01

    Oral rehabilitation of a child with Johanson-Blizzard syndrome (JBS). JBS is an extremely rare inherited disorder characterized by unusually small nose that appears 'beak shaped' due to the absence (aplasia) or underdevelopment (hypoplasia) of the nostrils (nasal alae), abnormally small, malformed primary (deciduous) teeth and misshapen or absent secondary (permanent) teeth, hearing disorder, hypothyroidism, dwarfism, malabsorption and mental retardation. It is sometimes described as a form of ectodermal dysplasia. Oral findings in JBS are very obscure in the literature. The present report describes oral findings in an 8 years old boy with JBS and his oral rehabilitation. JBS has an emotional consequence for the affected individuals at early ages. Oral rehabilitation in this case had a very positive impact on the child's mind. Early identification and treatment of this disease is of great importance to rehabilitate the patient on functional, esthetic and psychological front.

  9. Atlas event production on the EGEE infrastructure

    CERN Document Server

    Espinal, X; Perini, L; Rod, W

    2007-01-01

    ATLAS is one of the four LHC (Large Hadron Collider) experiments at CERN, is devoted to study proton-proton and ion-ion collisions at 14TeV. ATLAS collaboration is composed of about 2000 scientists spread around the world. The activity of the experiment requirements for next year is of about 300TB of storage and a CPU power of about 13 Mski2sk, and is relying on GRID philosophy and EGEE infrastructure. Simulated events are distributed over EGEE by the Atlas production system. Data has to be processed and must be accessible by a huge number of scientists for analysis. The throughput of data for Atlas experiment is expected to be of 320 MB/s with an integrated amount of data per year of ~10Pb. The processing and storage need a distributed share of resources, spread worldwide and interconnected with GRID technologies as the requirements are so demanding for the LHC. In that sense event production is the way to produce, process and store data for analysis before the experiment startup, and is performed in a distr...

  10. Tycoon market-based system: integration with EGEE

    CERN Document Server

    Dana Perez, J M

    2007-01-01

    Tycoon is a market-based system for trading resources. The idea is to integrate Tycoon with EGEE, obtaining a dynamic Grid ready to share resources with others (Universities, research centres, etc.). Tycoon will run as a new service, deploying and destroying virtual machines (Worker Nodes and Computing Elements) on demand. Tycoon will give to EGEE a dynamic, flexible, secure and transparent platform/service to trade resources more efficiently. It could attract small and medium VOs to the EGEE project, they could take advantage of the Grid resources and obtain extra computing power while EGEE could obtain credits/money for its service. Our goal is to integrate Tycoon as a new service of EGEE, we do not have special requirements, we do not need to modify the EGEE middleware, Grid special services, etc. Standard and ‘tycoonized’ nodes (Computing Elements and Worker Nodes) must coexist in the same Grid, working without problems. Our main issue would be to ensure the security of the whole system (EGEE platform...

  11. Geographical failover for the EGEE-WLCG Grid collaboration tools

    OpenAIRE

    Mathieu, Gilles; Aidel, Osman; L'Orphelin, Cyril; Lichwala, Rafal; Pagano, Alfredo; Cavalli, Alessandro

    2016-01-01

    International audience; Worldwide grid projects such as EGEE and WLCG need services with high availability, not only for grid usage, but also for associated operations. In particular, tools used for daily activities or operational procedures are considered critical. In this context, the goal of the work done to solve the EGEE failover problem is to propose, implement and document well-established mechanisms and procedures to limit service outages for the operations and monitoring tools used b...

  12. Structural Biology in the context of EGEE

    CERN Document Server

    García, D; Carazo, J M; Valverde, J R; Moscicki, J; Muraru, A

    2007-01-01

    Electron microscopy (EM) is a crucial technique, which allows Structural Biology researchers to characterize macromolecular assemblies in distinct functional states. Image processing in three dimensional EM (3D-EM) is used by a flourishing community (exemplarized by the EU funded 3D-EM NoE) and is characterized by voluminous data and large computing requirements, making this a problem well suited for Grid computing and the EGEE infrastructure. There are various steps in the 3D-EM refinement process that may benefit from Grid computing. To start with, large numbers of experimental images need to be averaged. Nowadays, typically tens of thousands of images are used, while future studies may routinely employ millions of images. Our group has been developing Xmipp, a package for single-particle 3D-EM image processing. Using Xmipp, the classification of 91,000 ribosome projections into 4 classes took more than 2500 CPU hours using the resources of the MareNostrum supercomputer at the Barcelona Supercomputing Centr...

  13. User and virtual organisation support in EGEE

    CERN Document Server

    Donno, Flavia

    2006-01-01

    User and virtual organisation support in EGEE Providing adequate user support in a grid environment is a very challenging task due to the distributed nature of the grid. The variety of users and the variety of Virtual Organizations (VO) with a wide range of applications in use add further to the challenge. The people asking for support are of various kinds. They can be generic grid beginners, users belonging to a given Virtual Organization and dealing with a specific set of applications, site administrators operating grid services and local computing infrastructures, grid monitoring operators who check the status of the grid and need to contact the specific site to report problems; to this list can be added network specialists and others. Wherever a user is located and whatever the problem experienced is, a user expects from a support infrastructure a given set of services. A non-exhaustive list is the following: a) a single access point for support; b) a portal with a well structured sources of information a...

  14. EGEE leaves a lasting legacy for the future

    CERN Multimedia

    Catherine Gater and Bob Jones

    2010-01-01

    With the LHC running smoothly since March this year, the World LHC Computing Grid, WLCG, is proving itself well up to the task of serving the particle physics community. It has also played an increasingly important role in other areas of science through the Enabling Grids for E-sciencE project, EGEE-III.   The final EGEE user forum held in Uppsala, Sweden in April 2010. It marked the end of the EGEE series of projects and the beginning of EGI. EGEE has been the primary grid infrastructure supporting WLCG (along with OSG and Nordugrid) and has nurtured innovative, world-class research across Europe and around the globe. EGEE-III brought together a computing infrastructure, software tools and services to support more than 10,000 scientific researchers across more than 170 research communities. Grids bring together computing and storage resources located in, owned and operated by different organisations located around the world. Connecting securely through the GÉANT internet network, gri...

  15. Scalability and performance analysis of the EGEE information system

    CERN Document Server

    Ehm, F; Schulz, M W

    2008-01-01

    Grid information systems are mission-critical components in today's production grid infrastructures. They provide detailed information about grid services which is needed for job submission, data management and general monitoring of the grid. As the number of services within these infrastructures continues to grow, it must be understood if the current information system used in EGEE has the capacity to handle the extra load. This paper describes the current usage of the EGEE information system obtained by monitoring the existing system. A test framework is described which simulates the existing usage patterns and can be used to measure the performance of information systems. The framework is then used to conduct tests on the existing EGEE information system components to evaluate various performance enhancements. Finally, the framework is used to simulate the performance of the information system if the existing grid would double in size.

  16. Errata - Reconstrução da asa nasal na Síndrome de Johanson Blizzard

    Directory of Open Access Journals (Sweden)

    Fernando Bray Beraldo

    2006-12-01

    Full Text Available Os autores relatam o caso de uma paciente pediátrica (três anos com aplasia das asas nasais, conseqüente à síndrome de Johanson-Blizzard. É descrita a utilização do retalho médio frontal bifurcado para reconstrução bilateral do forro e cobertura cutânea das asas nasais, obtendo bom resultado em um único tempo cirúrgico.

  17. From EGEE Operations Portal towards EGI Operations Portal

    Science.gov (United States)

    Cordier, Hélène; L'Orphelin, Cyril; Reynaud, Sylvain; Lequeux, Olivier; Loikkanen, Sinikka; Veyre, Pierre

    Grid operators in EGEE have been using a dedicated dashboard as their central operational tool, stable and scalable for the last 5 years despite continuous upgrade from specifications by users, monitoring tools or data providers. In EGEE-III, recent regionalisation of operations led the Operations Portal developers to conceive a standalone instance of this tool. We will see how the dashboard reorganization paved the way for the re-engineering of the portal itself. The outcome is an easily deployable package customized with relevant information sources and specific decentralized operational requirements. This package is composed of a generic and scalable data access mechanism, Lavoisier; a renowned php framework for configuration flexibility, Symfony and a MySQL database. VO life cycle and operational information, EGEE broadcast and Downtime notifications are next for the major reorganization until all other key features of the Operations Portal are migrated to the framework. Features specifications will be sketched at the same time to adapt to EGI requirements and to upgrade. Future work on feature regionalisation, on new advanced features or strategy planning will be tracked in EGI- Inspire through the Operations Tools Advisory Group, OTAG, where all users, customers and third parties of the Operations Portal are represented from January 2010.

  18. Jutuvõistluse "Musta mantliga mees" võitis Katrin Johanson

    Index Scriptorium Estoniae

    2007-01-01

    Eduard Vilde muuseumi poolt läbi viidud krimi- ja põnevusjuttude võistlusest "Musta mantliga mees". Žürii: Karl Martin Sinijärv, Juhan Habicht, Paul Pajos, Rebekka Lotman, Kristin Rammus, Piret Meos.Võitja: Katrin Johanson, teine koht: Taavet Kase, kolmas koht: Imre Kõuts. Ajalehe "Postimees" eriauhinnad said: Juhan Voolaid, Hella Riisalu, Stina Maria Vilt, Sirle Poikkanen, Märt Kivimäe. Tallinna noorte infokeskuse auhinnad: Juhan Voolaid, Sirle Poikkalainen, Lilli Anderson, Aino Rätsep. Eduard Vilde muuseumi eriauhinnad: Merilin Jürjo, Laura Pirso

  19. Data of evolutionary structure change: 1EGED-1SIRA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EGED-1SIRA 1EGE 1SIR D A -------LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWE...1SIR A 1SIRA MSVQSSLVMHP ...1SIR A 1SIRA AHYNSSNKSYTL...1SIR A 1SIRA LGPTI-KGYGC ...1SIR A 1SIRA LPGAS-SLGGP

  20. Data of evolutionary structure change: 1EGED-2EBAD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EGED-2EBAD 1EGE 2EBA D D ----LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDK...ID> D 2EBAD VSVQSSLVM...tryChain> 2EBA D 2EBAD SDPYGNMKTR...el> 2 2EBA D 2EBAD...Chain>D 2EBAD PKALG-LKAPL

  1. Parallel execution of chemical software on EGEE Grid

    CERN Document Server

    Sterzel, Mariusz

    2008-01-01

    Constant interest among chemical community to study larger and larger molecules forces the parallelization of existing computational methods in chemistry and development of new ones. These are main reasons of frequent port updates and requests from the community for the Grid ports of new packages to satisfy their computational demands. Unfortunately some parallelization schemes used by chemical packages cannot be directly used in Grid environment. Here we present a solution for Gaussian package. The current state of development of Grid middleware allows easy parallel execution in case of software using any of MPI flavour. Unfortunately many chemical packages do not use MPI for parallelization therefore special treatment is needed. Gaussian can be executed in parallel on SMP architecture or via Linda. These require reservation of certain number of processors/cores on a given WN and the equal number of processors/cores on each WN, respectively. The current implementation of EGEE middleware does not offer such f...

  2. University Students' Perceptions and Attitudes about Freedom of Claiming Educational Rights: Ege University

    Science.gov (United States)

    Akçay, Recep Cengiz; Üzüm, Püren Akçay

    2016-01-01

    The main purpose of this study is to define perceptions and attitudes of university students about freedom of claiming their educational rights. Research was designed within the framework of phenomenology which is one of the qualitative research designs. The study was conducted with 10 students from EGE University in the academic year of…

  3. "EGEE'06 - Capitalising on e-infrastructure" 25-29 September 2006, International Conference Centre (CICG) Geneva Switzerland

    CERN Multimedia

    2006-01-01

    EGEE'06 is the key Grid event of 2006, bringing together researchers, politicians, members of industry and the international community to discuss how to capitalise on past investments and plan for a sustainable future for Grid technology.

  4. Experiences in the Gridification of the Geant4 Toolkit in the WLCG/EGEE Environment

    CERN Document Server

    Mendez-Lorenzo, R; Ribon, A

    2007-01-01

    The general patterns observed in supporting the Geant4 application in the EGEE infrastructure are discussed. Regression testing of Geant4 public releases is in the focus of this paper. Geant4 is a toolkit for the Monte Carlo simulation of the interaction of particle with matter, used by a wide field of research, including high energy and nuclear physics and also medical, accelerator and space physics studies. The support required for the release regression testing of Geant4 toolkit, including setting up of the new, official Virtual Organization in the EGEE, is explained. Recent developments of automatic regression testing suites and the benefits of the optimization layer above the standard Grid infrastructure are presented.

  5. Definition and implementation of a SAML-XACML profile for authorization interoperability across grid middleware in OSG and EGEE

    Energy Technology Data Exchange (ETDEWEB)

    Garzoglio, Gabriele; Alderman, Ian; Altunay, Mine; Anathakrishnan, Rachana; Bester, Joe; Chadwick, Keith; Ciaschini, Vincenzo; Demchenko, Yuri; Ferraro, Andrea; Forti, Alberto; Groep, David; /Fermilab /NIKHEF, Amsterdam /Brookhaven /Amsterdam U. /SWITCH, Zurich /Bergen U. /INFN, CNAF /Argonne /Wisconsin U., Madison

    2009-04-01

    In order to ensure interoperability between middleware and authorization infrastructures used in the Open Science Grid (OSG) and the Enabling Grids for E-sciencE (EGEE) projects, an Authorization Interoperability activity was initiated in 2006. The interoperability goal was met in two phases: first, agreeing on a common authorization query interface and protocol with an associated profile that ensures standardized use of attributes and obligations; and second, implementing, testing, and deploying, on OSG and EGEE, middleware that supports the interoperability protocol and profile. The activity has involved people from OSG, EGEE, the Globus Toolkit project, and the Condor project. This paper presents a summary of the agreed-upon protocol, profile and the software components involved.

  6. Modalità di immissione elettrica di liquidi nel suolo (EGE integrale

    Directory of Open Access Journals (Sweden)

    A. Belluigi

    1965-06-01

    Full Text Available Si da la teoria dell'elettrogetto EGE integrale EGEI,un liquido, isobaricamente immesso tramite anodo in un mezzo poroso, esua rimozione (più o meno parziale, ritmica o no, al catodo.Caratterizzano quest'effetto elettrogeocinetico: pressioni idrogeostatica,catodica, portate anodica e catodica, liquidi immessi, estratti, ritenuti nelterreno.Con elettrotrattamento a tensione (c.c. costante, rapidi emungimenti,sufficientemente distanziati nel tempo, le precedenti grandezze, semplificate,constano di più addendi, i primi dei quali coincidenti con quelli già riconosciutiper l'EGE parziale (senza prelievi fluidi, altri apporti specifici dell'EGEintegrale (con prelievi fluidi.L'assorbimento anodico appare dapprima quasi insensibile al pompaggio,aumenta, tocca un massimo, torna a diminuire più dolcemente neltempo.L'effetto estrattivo si fa risentire, con incremento iniettivo massimosfasato in ritardo, per poi estinguersi.Isoprelievi catodici, intervallati con tempi adeguati (frequenza ottima,correlativi ad adduzioni anodiche, comporteranno « contenimenti fluidi massimi», notevolmente maggiori che per intervalli diversi.Così operando, pur sostando al « monoprelievo », si realizza un « invasamentodi liquido » massimo possibile, in tempo relativamente breve.

  7. Design of new plasmepsin inhibitors: a virtual high throughput screening approach on the EGEE grid.

    Science.gov (United States)

    Kasam, Vinod; Zimmermann, Marc; Maass, Astrid; Schwichtenberg, Horst; Wolf, Antje; Jacq, Nicolas; Breton, Vincent; Hofmann-Apitius, Martin

    2007-01-01

    Though different species of the genus Plasmodium may be responsible for malaria, the variant caused by P. falciparum is often very dangerous and even fatal if untreated. Hemoglobin degradation is one of the key metabolic processes for the survival of the Plasmodium parasite in its host. Plasmepsins, a family of aspartic proteases encoded by the Plasmodium genome, play a prominent role in host hemoglobin cleavage. In this paper we demonstrate the use of virtual screening, in particular molecular docking, employed at a very large scale to identify novel inhibitors for plasmepsins II and IV. A large grid infrastructure, the EGEE grid, was used to address the problem of large computation resources required for docking hundreds of thousands of chemical compounds on different plasmepsin targets of P. falciparum. A large compound library of about 1 million chemical compounds was docked on 5 different targets of plasmepsins using two different docking software, namely FlexX and AutoDock. Several strategies were employed to analyze the results of this virtual screening approach including docking scores, ideal binding modes, and interactions to key residues of the protein. Three different classes of structures with thiourea, diphenylurea, and guanidino scaffolds were identified to be promising hits. While the identification of diphenylurea compounds is in accordance with the literature and thus provides a sort of "positive control", the identification of novel compounds with a guanidino scaffold proves that high throughput docking can be effectively used to identify novel potential inhibitors of P. falciparum plasmepsins. Thus, with the work presented here, we do not only demonstrate the relevance of computational grids in drug discovery but also identify several promising small molecules which have the potential to serve as candidate inhibitors for P. falciparum plasmepsins. With the use of the EGEE grid infrastructure for the virtual screening campaign against the malaria

  8. Migration to the GLUE 2.0 information schema in the LCG/EGEE/EGI production Grid

    Science.gov (United States)

    Burke, Stephen; Field, Laurence; Horat, David

    2011-12-01

    The GLUE information schema has been in use in the LCG/EGEE production Grid since the first version was released in 2002. In 2008 a major redesign of GLUE, version 2.0, was defined in the context of the Open Grid Forum. The implementation of the publication and use of the new schema is a complex process which needs to be carefully managed to avoid any disruption to the production service, especially in the light of the end of the EGEE project and the transition to the new middleware and operational structures in EGI. In this paper we discuss the LDAP rendering of the schema, the upgrading of the Grid information system to allow both schemas to be used in parallel, the design and rollout of information providers, and the plans for migrating client software which uses the schema information. In particular we consider the implications for the specific requirements of the LCG project, especially regarding storage systems, accounting and monitoring.

  9. The Mooring Pattern Study for Q-Flex Type LNG Carriers Scheduled for Berthing at Ege Gaz Aliaga LNG Terminal

    Directory of Open Access Journals (Sweden)

    Selcuk Nas

    2014-12-01

    Full Text Available Ever growing energy industry requires larger quantities of LNG to be transported by bigger ships between terminals. Every day, new kind of large vessels created by new technologies, and these are used to trade around the globe. This is the dynamic change in shipping industry. But on the other hand these new vessels need to safely berth to existing terminals which we may accept as more static part of the trade. Thus this study born by the request of Ege Gaz Aliaga LNG Terminal management to determine if it is safe to berth to the terminal by a new breed of large LNG carrier type named as Q-Flex and Q-Max. Transas Bridge Simulator NTPRO 5000 series was used in this study for extensive experiments which had been simulated by the use of hook function. During the study, every force applied to mooring hooks and dolphins by the ship lines were divided into 3 dimensions and then measured by simulation experiments. With analysis of the data, required hook and dolphins strengths were determined for the safe mooring arrangements. Upon the completion of the study Ege Gaz Aliaga LNG Terminal became the first safe berth for Q-Flex type vessels in the Mediterranean and the Black Sea. And finally all experiments were confirmed with real life experience when the first Q-Flex type LNG carrier berthed to the Ege Gaz Aliaga LNG Terminal.

  10. Validity and reliability of a new test for Turkish-speaking aphasic patients: Ege Aphasia Test.

    Science.gov (United States)

    Calis, Funda Atamaz; On, Arzu Yagiz; Durmaz, Berrin

    2013-01-01

    Due to the fact that the phonetic, morphological and syntactic structures of the Turkish language differ significantly from other European languages, the translated forms of the currently available aphasia assessment batteries are not adequate for Turkish-speaking aphasic patients. The aim of this study was to assess the validity and reliability of the Ege Aphasia Test that we have developed. The test, which includes the 8 subtests of praxia, spontaneous language, auditory and verbal comprehension, repetition, naming, reading, writing and calculating, was applied into 100 aphasic patients, 40 dysarthric patients and 40 healthy subjects. All test-retest intra-class correlation coefficients were found to be excellent (ICC = 0.99). The Cronbach's coefficients ranged from 0.71 to 0.91. All the subtests showed significantly greater scores in aphasic patients (p Aphasia Test has an acceptable validity and reliability. It seems to be a promising battery for evaluation of aphasia in the Turkish language, which is spoken mainly in Turkey and in the surrounding regions. We believe that this study will pioneer the development of aphasia rehabilitation in these countries and contribute to future studies.

  11. Experiences with the GLUE information schema in the LCG/EGEE production grid

    Science.gov (United States)

    Burke, S.; Andreozzi, S.; Field, L.

    2008-07-01

    A common information schema for the description of Grid resources and services is an essential requirement for interoperating Grid infrastructures, and its implementation interacts with every Grid component. In this context, the GLUE information schema was originally defined in 2002 as a joint project between the European DataGrid and DataTAG projects and the US iVDGL. The schema has major components to describe Computing and Storage Elements, and also generic Service and Site information. It has been used extensively in the LCG/EGEE Grid, for job submission, data management, service discovery and monitoring. In this paper we present the experience gained over the last five years, highlighting both successes and problems. In particular, we consider the importance of having a clear definition of schema attributes; the construction of standard information providers and difficulties encountered in mapping an abstract schema to diverse real systems; the configuration of publication in a way which suits system managers and the varying characteristics of Grid sites; the validation of published information; the ways in which information can be used (and misused) by Grid services and users; and issues related to managing schema upgrades in a large distributed system.

  12. Penning-trap Q-value determination of the Ga-71(v, e(-))Ge-71 reaction using threshold charge breeding of on-line produced isotopes

    NARCIS (Netherlands)

    Frekers, D.; Simon, M.C.; Andreoiu, C.; Bale, J. C.; Brodeur, M.; Brunner, T.; Chaudhuri, A.; Chowdhury, U.; Lopez-Urrutia, J. R. Crespo; Delheij, P.; Ejiri, H.; Ettenauer, S.; Gallant, A. T.; Gavrin, V.; Grossheim, A.; Harakeh, M. N.; Jang, F.; Kwiatkowski, A. A.; Lassen, J.; Lennarz, A.; Luichtl, M.; Ma, T.; Macdonald, T. D.; Mane, E.; Robertson, D.; Schultz, B. E.; Simon, V. V.; Teigelhoefer, A.; Dilling, J.

    2013-01-01

    We present a first direct Q-value measurement of the Ga-71(v, e(-))Ge-71 reaction using the TITAN mass-measurement facility at ISAC/TRIUMF. The measurements were performed in a Penning trap on neon-like Ga-71(21+) and Ge-71(22+) using isobar separation of the on-line produced mother and daughter

  13. Farklı Yonca (Medicago sativa L.) Genotiplerinin Ege Bölgesi Koşullarına Adaptasyonu

    OpenAIRE

    DEMİROĞLU, Gülcan; GEREN, Hakan; AVCIOĞLU, Rıza

    2015-01-01

    B u çalışma; 2002-2003 ve 2003-2004 yılı yetiştirme dönemlerinde, Ege Üniversitesi Ziraat Fakültesi Tarla Bitkileri Bölümü’nün Bornova’da bulunan deneme tarlaları ile Ödemiş Meslek Yüksek Okulu'na ait deneme tarlalarında farklı yonca genotiplerinin (Tru-test, Bacana, FG8R612 ve Elçi) morfolojik ve bazı agronomik özelliklerinin farklı toprak bünyelerindeki lokasyonlarda adaptasyonunu belirlemek amacıyla yürütülmüştür. Denemede; çiçeklenme gün sayısı, ana sap uzunluğu, ana sap kalınlığı, b...

  14. Towards sustainability: An interoperability outline for a Regional ARC based infrastructure in the WLCG and EGEE infrastructures

    CERN Document Server

    Field, L; Johansson, D; Kleist, J

    2010-01-01

    Interoperability of grid infrastructures is becoming increasingly important in the emergence of large scale grid infrastructures based on national and regional initiatives. To achieve interoperability of grid infrastructures adaptions and bridging of many different systems and services needs to be tackled. A grid infrastructure offers services for authentication, authorization, accounting, monitoring, operation besides from the services for handling and data and computations. This paper presents an outline of the work done to integrate the Nordic Tier-1 and 2s, which for the compute part is based on the ARC middleware, into the WLCG grid infrastructure co-operated by the EGEE project. Especially, a throughout description of integration of the compute services is presented.

  15. Blueprint and First Experiences Bridging Hardware Virtualization and Global Grids for Advanced Scientific Computing: Designing and Building a Global Edge Services Framework (ESF) for OSG, EGEE, and LCG

    CERN Document Server

    Rana, A S; Vaniachine, A; Wurthwein, F; Foster, I; Sotomayor, B; Freeman, T

    2006-01-01

    We report on first experiences with building and operating an edge services framework (ESF) based on Xen virtual machines instantiated via the workspace service in Globus toolkit, and developed as a joint project between EGEE, LCG, and OSG. Many computing facilities are architected with their compute and storage clusters behind firewalls. Edge services (ES) are instantiated on a small set of gateways to provide access to these clusters via standard grid interfaces. Experience on EGEE, LCG, and OSG has shown that at least two issues are of critical importance when designing an infrastructure in support of ES. The first concerns ES configuration. It is impractical to assume that each virtual organization (VO) using a facility will employ the same ES configuration, or that different configurations will coexist easily. Even within a VO, it should be possible to run different versions of the same ES simultaneously. The second issue concerns resource allocation: it is essential that an ESF be able to effectively gu...

  16. A Worldwide Production Grid Service Built on EGEE and OSG Infrastructures Lessons Learnt and Long-term Requirements

    Energy Technology Data Exchange (ETDEWEB)

    Shiers, J.; Dimou, M.; Mendez Lorenzo, P.

    2007-07-01

    Using the Grid Infrastructures provided by EGEE, OSG and others, a worldwide production service has been built that provides the computing and storage needs for the 4 main physics collaborations at CERN's Large Hadron Collider (LHC). The large number of users, their geographical distribution and the very high service availability requirements make this experience of Grid usage worth studying for the sake of a solid and scalable future operation. This service must cater for the needs of thousands of physicists in hundreds of institutes in tens of countries. A 24x7 service with availability of up to 99% is required with major service responsibilities at each of some ten {sup T}ier1{sup a}nd of the order of one hundred {sup T}ier2{sup s}ites. Such a service - which has been operating for some 2 years and will be required for at least an additional decade - has required significant manpower and resource investments from all concerned and is considered a major achievement in the field of Grid computing. We describe the main lessons learned in offering a production service across heterogeneous Grids as well as the requirements for long-term operation and sustainability. (Author)

  17. Picosecond excite-and-probe absorption measurement of the intra-2E(g)E(3/2)-state vibrational relaxation time in Ti(3+):Al2O3

    Science.gov (United States)

    Gayen, S. K.; Wang, W. B.; Petricevic, V.; Yoo, K. M.; Alfano, R. R.

    1987-01-01

    The Ti(3+)-doped Al2O3 has been recently demonstrated to be a tunable solid-state laser system with Ti(3+) as the laser-active ion. In this paper, the kinetics of vibrational transitions in the 2E(g)E(3/2) electronic state of Ti(3+):Al2O3a (crucial for characterizing new host materials for the Ti ion) was investigated. A 527-nm 5-ps pulse was used to excite a band of higher vibrational levels of the 2E(g)E(3/2) state, and the subsequent growth of population in the zero vibrational level and lower vibrational levels was monitored by a 3.9-micron picosecond probe pulse. The time evolution curve in the excited 2E(g)E(3/2) state at room temperature was found to be characterized by a sharp rise followed by a long decay, the long lifetime decay reflecting the depopulation of the zero and the lower vibrational levels of the 2E(g)E(3/2) state via radiative transitions. An upper limit of 3.5 ps was estimated for intra-2E(g)E(3/2)-state vibrational relaxation time.

  18. A Worldwide Production Grid Service Built on EGEE and OSG Infrastructures – Lessons Learnt and Long-term Requirements

    CERN Document Server

    Shiers, J; Dimou, M; CERN. Geneva. IT Department

    2007-01-01

    Using the Grid Infrastructures provided by EGEE, OSG and others, a worldwide production service has been built that provides the computing and storage needs for the 4 main physics collaborations at CERN's Large Hadron Collider (LHC). The large number of users, their geographical distribution and the very high service availability requirements make this experience of Grid usage worth studying for the sake of a solid and scalable future operation. This service must cater for the needs of thousands of physicists in hundreds of institutes in tens of countries. A 24x7 service with availability of up to 99% is required with major service responsibilities at each of some ten "Tier1" and of the order of one hundred "Tier2" sites. Such a service - which has been operating for some 2 years and will be required for at least an additional decade - has required significant manpower and resource investments from all concerned and is considered a major achievement in the field of Grid computing. We describe the main lessons...

  19. Kuzey Ege ve Marmara Denizi Kıyısal Yüzey Sularında Scyphomedusae ve Ctenophora Üzerine Yerinde Gözlemler.

    Directory of Open Access Journals (Sweden)

    Süleyman Mavili

    2015-12-01

    Full Text Available Skifomedüz ve ktenoforların dağılımı ve bolluğu, 1998 ve 2005 arasında yaz ve sonbahar dönemlerinde yerinde gözlemlerle incelenmiştir. Skifomedüzler (A. aurita, R. pulmo Kuzey Ege ve Marmara Denizi’nde geniş bir dağılım göstermiştir. Yazın baskın olan A. aurita sonbaharda azalmış, oysa R. pulmo bu dönemde belirgin olarak artmıştır. Ktenoforlar (M. leidyi, B. ovata Kuzey Ege’de bulunmamıştır. M. leidyi Marmara Denizi’nde 1999’da bol olarak bulunmuş, B. ovata’nın ortaya çıktığı 2000’de belirgin bir azalma göstermiştir. Her iki ktenofor da 2004 ve 2005’de çalışma bölgesinde bulunmamıştır. Bu da pek muhtemelen M. leidyi yoğunluğunda büyük bir azalmaya işaret etmektedir

  20. Foorumteater aitas lahendusi leida / Katrin Johanson

    Index Scriptorium Estoniae

    Johanson, Katrin

    2008-01-01

    Jaanipäeva eel korraldas Karksi-Nuia noortekeskus nädalase foorumteatri metoodikale keskendunud koolituslaagri, milles osales noorsootöötajaid seitsmest riigist. Tutvuti foorumteatri ja selle rakendamisvõimalustega õpetaja Gill Dowsetti juhendamisel

  1. Religiooni roll Nõukogude okupatsiooni ajal / Merje Talvik

    Index Scriptorium Estoniae

    Talvik, Merje

    2009-01-01

    Eesti kaitseväe kaplan ja Eesti Apostlik-Õigeusu Kiriku diakon Andrei Sõtšov kaitses Tartu ülikooli usuteaduskonnas doktoritöö "Eesti õigeusu piiskopkond nõukogude religioonipoliitika mõjuväljas 1954-1964"

  2. Evaluating the Johanson theory for titanium powder

    CSIR Research Space (South Africa)

    Chikosha, S

    2015-05-01

    Full Text Available Direct powder rolling (DPR)/roll compaction has been labelled a complex and sample sensitive process. As such the design of the instrument and the determination of the optimal processing conditions for a given feed are very challenging...

  3. Impact of comprehensive geriatric assessment on survival, function, and nutritional status in elderly patients with head and neck cancer: protocol for a multicentre randomised controlled trial (EGeSOR).

    Science.gov (United States)

    Brugel, Lydia; Laurent, Marie; Caillet, Philippe; Radenne, Anne; Durand-Zaleski, Isabelle; Martin, Michel; Baron, Melany; de Kermadec, Héloïse; Bastuji-Garin, Sylvie; Canouï-Poitrine, Florence; Paillaud, Elena

    2014-06-13

    Survival is poorer in elderly patients with head and neck squamous cell carcinomas [HNSCCs] than in younger patients. Possible explanations include a contribution of co-morbidities to mortality, frequent refusal of standard therapy, and the use of suboptimal treatments due to concern about toxicities. The Comprehensive Geriatric Assessment [CGA] is a multidimensional assessment of general health that can help to customise treatment and follow-up plans. The CGA has been proven effective in several health settings but has not been evaluated in randomised studies of patients with cancer. Our aim here was to assess the impact of the CGA on overall survival, function, and nutritional status of elderly patients with HNSCC. EGeSOR is an open-label, multicentre, randomised, controlled, parallel-group trial in patients aged 70 years or older and receiving standard care for HNSCC. The intervention includes four components: the CGA conducted by a geriatrician before cancer treatment, participation of the same geriatrician in cancer treatment selection, a standardised geriatric therapeutic intervention designed by the same geriatrician; and geriatric follow-up for 24 months. The primary endpoint, assessed after 6 months, is a composite criterion including death, functional impairment [Activities of Daily Living score decrease ≥ 2], and weight loss ≥ 10%. Secondary endpoints include progression-free survival, unscheduled admissions, quality of life, treatment toxicities, costs, and completion of the planned cancer treatment. A centralised online system is used to perform 1:1 randomisation with a minimisation algorithm for centre, age, T and N stages, and tumour site [oral, oropharyngeal, hypopharyngeal, or laryngeal]. The estimated sample size is 704 patients, who are being recruited by 14 centres in 9 French cities. EGeSOR is the first randomised trial of the CGA in elderly cancer patients. We expect the CGA to have direct clinical benefits on the management of elderly

  4. İzmir Körfezi'nde (Ege Denizi Kullanılan Sürüklenen Pelajik Uzatma Ağlarının Teknik Özellikleri.

    Directory of Open Access Journals (Sweden)

    Okan Akyol

    2015-12-01

    Full Text Available Bu çalışma, İzmir Körfezi’nde (Ege Denizi üç ana balıkçı limanından Güzelbahçe, Sahilevleri ve İnciraltı’nda kullanılan küçük ölçekli sürüklenen pelajik uzatma ağlarının teknik özelliklerini rapor etmektedir. Kıyı balıkçılığından 5 adedi solungaç, kalanı fanyalı olmak üzere toplam 7 değişik tipte sürüklenen pelajik ağ tanımlanmıştır. Körfezde ağların tamamının maksimum boyu 158 km olarak hesaplanmıştır

  5. Datça-Bozburun Yarımadası (Ege Denizi Kıyı Balıkçılığı ve Sorunları Üzerine Bir Araştırma.

    Directory of Open Access Journals (Sweden)

    Okan Akyol

    2015-12-01

    Full Text Available Bu çalışmada, Datça-Bozburun Yarımadası’nın kıyı balıkçılık aktiviteleri, hedef balık türleri, balıkçılık sorunları, balıkçı kooperatiflerinin özellikleri, balıkçı tekneleri ve barınakları araştırılmıştır. Örneklemeler iki balıkçı kooperatifi (Datça ve Karaköy ve 8 balıkçılık barınağında 2005-2006 yılları arasında yürütülmüştür. Bölgede toplam 32 kooperatif üyesi ile yaklaşık 170 balıkçı teknesi kaydedilmiştir. Üye sayılarına göre en büyük balıkçı kooperatifi Datça’dır. Bölgede kıyı balıkçılığı yoğun olarak paragat, sade ve fanyalı uzatma ağlarıyla yürütülmektedir. Uzatma ağı ve paragat balıkçılığında yakalanan balık ve omurgasızlar Ege ve Akdeniz’in yerleşik tipik balıklarıdır. Mullus barbatus, Sphyraena sphyraena, Seriola dumerilii, Pagellus erythrinus, Dentex dentex, Mullus surmuletus, Sarda sarda, Xiphias gladius, Epinephelus aeneus, Loligo vulgaris, Octopus vulgaris vb. ticari avdaki hedef türlerdir. Fakat bölgedeki balıkçılık aktiviteleri kısa balıkçılık sezonu, düşük balıkçılık kapasitesi ve az sayıdaki balıkçı nedeniyle göreceli olarak oldukça zayıf bulunmuştur

  6. Zoology Department, University Col/ege, Nairobi

    African Journals Online (AJOL)

    Figure 2: Typical heaping inside the artificial warren, with the younger animals forrnil'lg the: upper tie:r. than the adults ... artificial warren of a captive colony during the hot season. The simplest "heap" is ..... appeasement may be the poor near vision of hyrax which could result in mistaken interpreta- tion of the behaviour ...

  7. Keskealisena õppima, et elu oleks komm / Adele Johanson

    Index Scriptorium Estoniae

    Johanson, Adele

    2016-01-01

    Margot Adra läks Kehtnasse õppima toiduvalmistamise kunsti. Kaie Kahro õpib Tartu kutsehariduskeskuses arvutiga juhitava töötlemiskeskuse operaatoriks ja töötab ettevõttes Orthez OÜ, tema õpe on töökohapõhine

  8. Abieluakti koostamine EELKs - õigus või kohustus? / Merje Talvik

    Index Scriptorium Estoniae

    Talvik, Merje

    2008-01-01

    Vaimulike õigusest pärast siseministeeriumi korraldatava koolituse läbimist riigi nimel abielu sõlmida. Kommenteerivad Kristjan Luhamets, Rein Schihalejev, Mare Palgi, Illimar Toomet, Mart Jaanson, Anna-Liisa Vaher ja Kalle Gaston

  9. Õpilaskodude plussid ja miinused / Merje Kask

    Index Scriptorium Estoniae

    Kask, Merje

    2006-01-01

    Saaremaa Ühisgümnaasiumi haldusjuht Aado Haandi, Jõgeva maakonna alaealiste komisjoni esimees Jüri Ginter, Kaelase Kooli direktor Diana Tali, Otepää Gümnaasiumi direktor Aivo Meema, Tõstamaa Keskkooli direktor Toomas Mitt, Kunda Ühisgümnaasiumi õppealajuhataja Meelike Abroi ja Krabi Põhikooli direktor Ale Sprenk õpilaskodudest

  10. Inimese ärasaatmine on lugu teekonnast / Katrin Johanson

    Index Scriptorium Estoniae

    Johanson, Katrin

    2008-01-01

    Seoses kirjanik Tšõngõz Ajtmatovi surmaga meenutatakse tema teose järgi tehtud menulavastust Ugalas "Ja sajandist on pikem päev" (1985, lavastaja Kalju Komissarov). Ugalas on tema teostest lavale toodud ka "Kirju koer, kes jookseb mere kaldal" (1981, lavastaja Iskander Rõskulov)

  11. Usuteaduskonnas kaitsti kaks doktoritööd / Merje Talvik

    Index Scriptorium Estoniae

    Talvik, Merje, 1971-

    2009-01-01

    Tartu ülikooli usuteaduskonnas kaitsesid doktoritöö Roland Karo teemal "Eros ja müstika. Kas müstilised teadvusseisundid on seksuaalsete reaktsioonide evolutsioonilised kõrvalproduktid?" ja Olga Schihalejev teemal "Eesti noored, religioon ja religioosne mitmekesisus: isiklikud suhtumised ja kooli roll"

  12. Vahetuspere isa osutus seksuaalseks ahistajaks / Merje Pors ; kommenteerinud Oliver Kontram

    Index Scriptorium Estoniae

    Pors, Merje

    2011-01-01

    Vahetusõpilase ahistamise juhtumist Argentiinas, kus vahetuspere isa kuritarvitas seksuaalselt vahetusõpilast. Vahetusprogrammide kaudu välismaale õppima minejate arvu vähenemisest, mistõttu on programmid sunnitud ümber orienteeruma ja rohkem välisõpilasi Eestisse tooma

  13. Koolid jätsid murepoisi ukse taha / Merje Pors

    Index Scriptorium Estoniae

    Pors, Merje

    2010-01-01

    Lääne-Virumaalt Tallinnasse 9. klassi õppima asuda soovinud poissi ei võetud vastu seitsmes koolis, kuigi põhikooli- ja gümnaasiumiseaduse kohaselt on kool kohustatud lapse vastu võtma, kui koolis on vabu kohti

  14. Rock'n'roll'i hotellipidaja / Ants Johanson

    Index Scriptorium Estoniae

    Johanson, Ants, 1962-

    2008-01-01

    Ansamblist Rock Hotel (ansambli 30. sünnipäeva tähistamise juubelikontsertdid toimuvad 14. okt. Pärnu Endla teatris, 15. okt. Rakvere Teatris, 16. okt. Viljandi Pärimusmuusika Aidas, 17. okt. Paide kultuurikeskuses, 18. okt. Võru kultuurimajas Kannel, 19. okt. Vanemuise väikeses majas ja 20. okt. Vene Teatris, 9. okt. toimub Tallinnas Viru Keskuse kaupluses Rahva Raamat mälestusteraamatu "Aeg meid muutnud on? - Rock-Hotel 30" esitlus)

  15. Operating the LCG and EGEE Production Grids for HEP

    CERN Multimedia

    CERN. Geneva

    2004-01-01

    In September 2003 the first LCG-1 service was put into production at most of the large Tier 1 sites and was quickly expanded up to 30 Tier 1 and Tier 2 sites by the end of the year. Several software upgrades were made and the LCG-2 service was put into production in time for the experiment data challenges that began in February 2004 and continued for several months. In particular LCG-2 introduced transparent access to mass storage and managed disk-only storage elements, and a first release of the Grid File Access library. Much valuable experience was gained during the data challenges in all aspects from the functionality and use of the middleware, to the deployment, maintenance, and operation of the services at many sites. Based on this experience a program of work to address the functional and operational issues is being implemented. The goal is to focus on essential areas such as data management and to build by the end of 2004 a basic grid system capable of handling the basic needs of LHC c...

  16. Strominge in die vrouebew eging: 'n voorlopige raamwerk

    Directory of Open Access Journals (Sweden)

    M. van Niekerk

    1988-03-01

    Full Text Available The Biblical principle of reformation challenges the Christian to question the traditional position of women and if necessary to change it, as well as to critically evaluate the various trends within the women's movement. It is stated that the generalizing use of the term feminism has become outdated, and should be replaced by differentiated terminology. The latter should be based on critical nuancing, with due regard to the view of history, the approach to sexuality/sex and the religious directedness of each specific trend or school of thought. Against the background of the sexism and traditionalism of male chauvinism , this article offers a prelim inary framework from which a number of fem inist and moderate trends within the women's movement can be identified. Within feminism a distinction is drawn between egalitarian and gynaecentric (neo-sexist trends. The moderate wing of the women's movement includes a humanist and a Christian approach, with androgynous and holistic views respectively as examples of these. Finally the author points out that the use of the Bible by feminist theologians and other representatives of the women's movement offers no guarantee for Scriptural viewpoints, and warns against generalizing judgments about proponents of women's rights.

  17. Toward cooperative security? International integration and the construction of security in Estonia / Merje Kuus

    Index Scriptorium Estoniae

    Kuus, Merje

    2002-01-01

    Autor leiab, et Eesti ühinemine rahvusvaheliste organisatsioonidega on suures osas seotud julgeolekupoliitiliste kaalutlustega. Võimalikud ohud rahvuslikule julgeolekule ja võimalikud vastumeetmed nende vältimiseks

  18. Kellele EXPOrt? = EXPOrt for whom? / Tõnis Kimmel, Merje Müürisepp

    Index Scriptorium Estoniae

    Kimmel, Tõnis, 1977-

    2010-01-01

    Maailmanäituse EXPO 2010 eripärast. Viimase aastakümne arengutest Shanghais, maailmanäituse alast. Maailmanäituse teema "Parem linn, parem elu" käsitlemisest, oma sõnumi edastamisest. Suurbritannia (Thomas Heaterwick), Šveitsi (Buchner Bründler Architekten), Taani (Bjarke Ingels Group), Alžeeria, Hollandi (John Kormeling) ja Eesti paviljonidest, paremate linnaliste praktikate alast

  19. Presidendi kantselei: Ilves ei üritanud sõjaraamatut tsenseerida / Merje Pors

    Index Scriptorium Estoniae

    Pors, Merje

    2011-01-01

    Presidendi kantselei lükkab ümber Briti ajalehe The Telegraph väite, nagu oleks president Toomas Hendrik Ilves avaldanud survet Toby Harndeni raamatu "Dead Men Risen: The Welsh Guards and the Real Story of Britain's War in Afghanistan "("Ülestõusnud surnud: Walesi kaardivägi ja tegelik lugu brittide sõjast Afganistanis") tsenseerimiseks

  20. Eesti aja arhitektuur : Eugen Habermann 125. Herbert Johanson 125 / Ike Volkov

    Index Scriptorium Estoniae

    Volkov, Ike, 1951-

    2010-01-01

    Näitus Eesti Arhitektuurimuuseumis 04. 12. 2009-07. 03. 2010. Eugen Habermannist ja Herbert Johansonist, nende tegevusest ja loomingust. Selle aja ja praegustest probleemidest ning lahendusvõimalustest

  1. Märkmeid Thbilisist / Tõnis Kimmel, Merje Müürisepp

    Index Scriptorium Estoniae

    Kimmel, Tõnis, 1977-

    2007-01-01

    Muljeid Thbilisi arhitektuurist. Hotellist "Iveria" (1967, arhitekt O. Kalandarishvili), Püha Kolmainu kirikust (2003), purskkaevudest, Teedeministeeriumi insenerikorpuse hoonest (1974, arhitektid G. Tshahhava, Z. Dzhalagania, T. Thilava jt.), Poliitharidusmaja fassaadist (1980, arhitekt A. Abramashvili, fassaad Z. Tsereteli), säilinud vanadest interjööridest. 6 värv. vaadet

  2. The Leech with a taste for oranges / Merje Järv-Griffiths

    Index Scriptorium Estoniae

    Järv-Griffiths, Merje

    2007-01-01

    Rockansamblist Leech (kontserdid 23. nov. klubis Rockstar's Tallinnas, 30. nov. Lutsu Teatris Tartus ja 21. dets. festivalil Green Christmas Rakveres), heliplaadist "Tram-O-Gram" (vt. www.leechband.net)

  3. Eesti on õnnetuste tõttu hukkuvate laste poolest esirinnas / Merje Pors

    Index Scriptorium Estoniae

    Pors, Merje

    2011-01-01

    Majandusliku Koostöö ja Arengu Organisatsiooni (OECD) värskest raportist "Doing Better for Families" selgub, et Eestis on aastatel 1997-2008 õnnetuste tagajärjel surma saanud 100 000 kuni 14-aastase lapse kohta enam poisse ja türdukuid kui üheski teises OECD liikmesriigis

  4. Euroopa tunnustas programmi „Eesti IT Akadeemia” / Erki Urva ; intervjueerinud Merje Pors

    Index Scriptorium Estoniae

    Urva, Erki, 1960-

    2014-01-01

    Intervjuu hariduse infotehnoloogia sihtasutuse (HITSA) juhatuse esimehe Erki Urvaga, kes tutvustas üleeuroopalisel konverentsil „E-skills 2013” meie ülikoolide ja IT-ettevõtete koostööprogrammi „Eesti IT Akadeemia”

  5. Hakkajad noored said toetust välismaal õpingute jätkamiseks / Merje Pors

    Index Scriptorium Estoniae

    Pors, Merje

    2011-01-01

    Sihtasutus Archimedes andis 24. augustil 2011 Tallinna reaalkoolis toimunud üritusel välja kümme 4000 euro suurust preemiat andekatele noortele, kes alustavad või jätkavad bakalaureuseõpinguid maailma tunnustatud ülikoolides. Stipendiaate õnnitles ka president Toomas Hendrik Ilves

  6. From threats to risk : the reconfiguration of security debates in the context of regional co-operation / Merje Kuus

    Index Scriptorium Estoniae

    Kuus, Merje

    2003-01-01

    Eesti julgeolek on viimasel ajal ümber mõtestatud kitsalt sõjalisest valdkonnast palju laiemale valdkonnale; kultuur, identiteet ning moraalsed väärtused on nihkunud kesksele kohale julgeolekuteemalistes diskussioonides

  7. Abieluakti koostamine EELKs - õigus või kohustus? / Kristjan Luhamets, Rein Schihalejev, Mare Palgi...[jt.] ; interv. Merje Talvik

    Index Scriptorium Estoniae

    2008-01-01

    Vastavalt perekonnaseaduse muudatustele on siseministeeriumi poolt korraldatava koolituse läbinud vaimulikul õigus abielu sõlmimiseks. Vaimulikud vastavad küsimusele, kuidas nad näevad perekonnaseisuametniku ja jumalasulase tööd ühendatuna. Lisatud: [koguduse vaimulikul on õigus keelduda abielu sõlmimisest, kui...

  8. Advantages of pre-production WLCG/EGEE services for VOs and users

    CERN Document Server

    Thackray, N; Fernandez Sanchez, C; Freire Garcia, E; Simon Garcia, A; Lopez Cacheiro, J

    2008-01-01

    The benefits that the Pre-Production Service (PPS) can offer to VOs and new users will be shown. Current PPS processes will be described so they have a better understanding of the PPS environment. PPS offers a proper place where VOs can test their applications and check their compatibility with upcoming middleware releases. PPS could help VOs improve their applications and at the same time, VOs would be helping PPS to produce better tested middleware releases that would go into Production (PROD) Currently a well-defined set of procedures is followed in PPS, beginning with the pre-deployment activity and finishing with the approval of a new middleware release that can go into PROD. The PPS Coordination Team takes care of supervising all these steps, mainly trying to spot possible bugs in the middleware before it goes into PROD. Unfortunately, VO contribution in this part of the deployment is currently very limited and the PPS team does not have a full feedback from these important groups. One of the problems i...

  9. Role of EGE-related Growth Factor Cripto in Murine Mammary Tumorigenesis

    Science.gov (United States)

    1998-10-01

    which may confer association with the cell membrane [10, 11]. Despite their relatively low sequence conservation (about 30% amino acid identity...B. A. Beta- amyloid neurotoxicity requires fibril formation nod iu 1nhibe,1y homogenates for human PSI fragments. Transgene expression was also Congo...human breast tumorigenesis. To determine whether Cripto has a causal role in tumorigenesis, and whether it may be involved in normal breast development

  10. Euroopa keelemapp võõrkeele õpetamisel / Ege Meister, Triin Brenner

    Index Scriptorium Estoniae

    Meister, Ege

    2003-01-01

    29.01.2003 toimus Tallinna Polütehnikumis koostöös Riikliku Eksami- ja Kvalifikatsioonikeskusega kutsekoolide inglise keele õpetajate täienduskoolitusseminar "Euroopa keelemapi tasemete kasutamine ja enesehindamine"

  11. Ege aphasia test: Description of the test and performance in normal subjects

    National Research Council Canada - National Science Library

    DURMAZ, Berrin; ATAMAZ, Funda; ON, Arzu, Yağız

    2007-01-01

    ... oluşan 9 alt testten oluşmaktaydı. Test 133 sağlıklı gönüllü tarafından dolduruldu. Gönüllüler yaş, cins ve eğitim düzeylerine göre sınıflandırıldılar. Yirmi beş gönüllü test-tekrar test...

  12. Tööandja brand'i eesmärk on tööotsijale ihaldatavaks muutumine / Ege Heeringas

    Index Scriptorium Estoniae

    Heeringas, Ege

    2007-01-01

    TTÜ tudengi Kadi Tamkõrve magistritöö teemaks oli tööandja brand ja selle loomine. Vt samas lk. 21-22 intervjuud reklaamifirma Kontuur Leo Burnett juhi Jane Oblikasega. Tööandjad alahindavad tööotsijate emotsionaalset poolt

  13. European multicentre evaluation of the Du Pont Dimension 380 under the auspices of the European Group for the Evaluation of Analytical Systems in Laboratory Medicine (EGE-Lab).

    Science.gov (United States)

    Hänseler, E; Vonderschmitt, D; Haeckel, R; Römer, M; Collombel, C; Goudable, J; Pourcher, E

    1991-01-01

    The Clinical Chemistry Analyzer Dimension 380 manufactured by Du Pont de Nemours was tested in a multicentre evaluation according to the guide-lines of the European Committee for Clinical Laboratory Standards (ECCLS) and in part to the protocol of the Société Française de Biologie Clinique (SFBC). The instrument and the reagents were evaluated as a system, since both reagents and reagent cartridges are specifically designed for the instrument. Fourteen analytes including electrolytes, substrates and enzymes were tested. The evaluators summarized their experience as follows: 1. All parameters tested yield results comparable to established procedures. 2. Very good performance of the ion-selective-electrode unit. 3. The imprecision data of the system are, for most parameters, between 1 and 4% CV and thus equal to or better than those of the instruments compared. 4. No reagent or sample carry-over was detected after a minor modification of the instrument. 5. The linearity of Dimension test methods in general covers the range stated by the manufacturer. 6. Very good stability of the calibration curves (up to 2 months). 7. Good practicability of the whole system, including handling of reagents and a very user-friendly software.

  14. Hääletades läbi Eesti : ehk intervjuu kahe noorega, kelle jaoks loodus on sõber ja hääletamine nauding / Tea Jänes, Allan Kahar ; küsitlenud Merje Pors

    Index Scriptorium Estoniae

    Jänes, Tea

    2007-01-01

    Intervjuu tudengite igasuvise hääletusvõistluse "Kas tunned maad VII" kolmanda koha omanikega Tartu Ülikooli keskkonnatehnoloogia magistrandi Tea Jänese ja Luua Metsanduskoolis loodusretkede juhi ametit õppiva Allan Kahariga

  15. In vitro pollen quantity, viability and germination tests in quince

    African Journals Online (AJOL)

    use

    2011-11-21

    Nov 21, 2011 ... Quince (Cydonia oblonga Mill.) cvs. Ekmek, Eşme, Limon, Ege 2, Ege 22, Ege 25 and Quince-A rootstock pollens were collected in April from the unopened pink balloon-stage flowers on mature trees. The pollen amount was between 20063 pollen/flower ('Ege 25') and 11906 pollen/flower ('Limon').

  16. In vitro pollen quantity, viability and germination tests in quince ...

    African Journals Online (AJOL)

    Quince (Cydonia oblonga Mill.) cvs. Ekmek, Esme, Limon, Ege 2, Ege 22, Ege 25 and Quince-A rootstock pollens were collected in April from the unopened pink balloon-stage flowers on mature trees. The pollen amount was between 20063 pollen/flower ('Ege 25') and 11906 pollen/flower ('Limon') with hemacytometer.

  17. Tallinna Teeninduskooli juurdeehitus = Addition to the Tallinn School of Servise / Maarja Nummert ; intervjueerinud Margit Mutso

    Index Scriptorium Estoniae

    Nummert, Maarja, 1944-

    2012-01-01

    Tallinnas Majaka t. 2 asuva Tallinna Teeninduskooli juurdeehituse arhitektuursest lahendusest ja sisekujundusest. Arhitekt ja sisearhitekt Maarja Nummert (Pikoprojekt). Ajaloolise hoone (1932) autor Herbert Johanson

  18. Ernst Enno etluskonkursil kõlas saja aasta tagune luule / Krista Kumberg

    Index Scriptorium Estoniae

    Kumberg, Krista, 1959-

    2007-01-01

    Läänemaal toimus maakondlik Ernst Ennole pühendatud etluskonkurss. E. Enno nimelise etluskonkursi 2007 "Saja aasta tagused luuletused" parimad etlejad olid Mike Richard Koch, Janno Allika, Hanna Ring, Karl Poll, Britta Sool, Antero Rea, Jennifer Cohen, Brita Kaljuvee, Eva-Maria Brock, Kaupo Engel, Liisi Räli, Laivi Kovalenko, Merje Viigand, Carmen Freimann, Rauno Punk, Maarja Palmiste

  19. Uued aiaraamatud

    Index Scriptorium Estoniae

    2007-01-01

    Tallinnas 2007. a. kirjastuselt Maalehe Raamat ilmunud Bertil K. Johansoni raamatust "Aialilled : kevadest talveni", Börje Erikssoni ja Pär Schyllanderi raamatust "Veekogud aias : esmamõtetest teostuseni" (fotod: B. K. Johanson), Susanna Widlundhi raamatust "Pojengid" (fotod: B. K. Johanson), kirjastuselt Sinisukk ilmunud raamatust "Aiakujunduse käsiraamat : kujunda ja hoolda oma koduõue"

  20. Eesti saatkonna ehitamisest Riiga 1938. aastal / Karin Hallas-Murula

    Index Scriptorium Estoniae

    Hallas-Murula, Karin, 1957-

    2008-01-01

    Riiga Eesti saatkonna hoone rajamise katsest. Välisministeeriumi poolt Aleksander Nürnbergilt tellitud eskiisist. 1938. a. korraldatud arhitektuurikonkursist ja selle tulemustest (I preemia - Erich Jacoby ja Hermann Berg, II - Herbert Johanson ja Lorenz Johanson, 1939. aastast Lorenz Haljak, III - Elmar Lohk)

  1. Edremit Körfezi (Ege Denizi Kıyı Balıkçılığı Üzerine Bir Araştırma.

    Directory of Open Access Journals (Sweden)

    Tevfik Ceyhan

    2015-12-01

    Full Text Available Bu çalışmada, Edremit Körfezi’nde yer alan su ürünleri kooperatifleri ve balıkçı barınaklarının özellikleri, küçük ölçekli balıkçılık faaliyetleri ve bazı balıkçılık sorunları incelenmiştir. Örneklemeler Ocak, Haziran ve Temmuz 2005’te 6 adet su ürünleri kooperatifinde yürütülmüştür. Edremit Körfezi’nde kooperatif ve balıkçı barınaklarında sırasıyla 284 üye ve 655 balıkçı teknesi kaydedilmiştir. Körfezde kıyı balıkçılığı yoğun olarak kıyı sürütme ağları ve uzatma ağlarıyla yürütülmektedir

  2. Ege Denizinde Yaşayan Kaya Balıklarının (Gobius niger L., 1758 Karaciğer Dokusunda Bazı Ağır Metallerin Birikimi.

    Directory of Open Access Journals (Sweden)

    Selma Katalay

    2015-12-01

    Full Text Available Bu çalışmada petrol rafinerisinin bulunduğu Aliağa Körfezi’nin çeşitli yerlerinden toplanmış kaya balıklarının (Gobius niger karaciğer dokusu alınarak ağır metal içerikleri (Cd, Ni, Se, Zn, Cu,Cr ölçülmüştür. Aliağa bölgesinden alınan örneklerde ağır metal birikimine minumum düzeyde rastlanmıştır. Ayrıca alınan datanın fiziksel (boy ve mevsime (yaz ve ilkbahar göre dağılımı incelendiğinde metal birikiminin dağılımında farklılıklar olduğu saptanmıştır

  3. Hydrophobic nano-carrier for lysozyme adsorption

    Indian Academy of Sciences (India)

    Department of Biochemistry, Ege University, 35040 ˙Izmir, Turkey; Kocarlı Vocational and Training School, Adnan Menderes University, 09010 Aydın, Turkey; Ege Higher Vocational School, Ege University, 35040 ˙Izmir, Turkey; Department of Chemistry, Faculty of Arts and Science, Celal Bayar University, 45140 Manisa, ...

  4. Kolmas aed = The Third Garden / Martin Melioranski

    Index Scriptorium Estoniae

    Melioranski, Martin

    2006-01-01

    Aed ja eramu Meriväljal Viimsi ja Väina tee nurgal. Projekt: Arhitektuuriagentuur. Autorid: Inga Raukas, Toomas Tammis, Tarmo Teedumäe. Haljastuse konsultant Signe Peipman. Projekt 2005, valmis 2006. Aed ja eramu Naeri tänaval. Projekt: Kolm Pluss Üks Arhitektid. Autorid: Markus Kaasik, Andres Ojari, Ilmar Valdur, Merje Müürsepp, Kalle Komissarov (2002). Projekt 2002-2004, valmis 2005. Ill.: kaks plaani, 6 värv. vaadet

  5. ...ja valgus sai / Piret Veigel

    Index Scriptorium Estoniae

    Veigel, Piret, 1961-

    2004-01-01

    Arhitektuuribüroo 3+1 arhitektide Merje Müürisepa, Ilmar Valduri, Markus Kaasiku, Kalle Komissarovi, Indrek Tiigi ja Andres Ojari projekteeritud eramust. Välisviimistluses on kasutatud okaspuulauda. Sisekujunduses on põhitoon valge. Elutoas on klaaskamin, esikut eraldavad elutoast metallraamil kangast lükandseinad jm. A. Ojari ja I. Valdur hoone arhitektuursest lahendusest. Ill.: I ja II korruse plaan, 1 välis- ja 11 sisevaadet.

  6. Puhtuse ülemlaul / Jaan J. Leppik

    Index Scriptorium Estoniae

    Leppik, Jaan J., 1969-

    1999-01-01

    Maurice Maeterlincki "Pelléas ja Mélisande" Theatrumis, lavastaja Lembit Peterson, kunstnik Lilja Blumenfeld, näitlejad Lembit Peterson, Anneli Tuulik, Leino Rei, Kärt Johanson, Ülle Kaljuste. Esietendus 19. nov. 1999

  7. Il y a des endroits o̮ lòn ne voit jamais le soleil / Margit Adorf

    Index Scriptorium Estoniae

    Adorf, Margit, 1974-

    1999-01-01

    Maurice Maeterlincki "Pelleas ja Melisande" Theatrumis, lavastaja Lembit Peterson, kunstnik Lilja Blumenfeld,näitlejad Lembit Peterson, Anneli Tuulik, Leino Rei, Kärt Johanson, Ülle Kaljuste. Esietendus 19. nov. 1999

  8. Johanson–Blizzard syndrome. Report of a case and review of the literature

    OpenAIRE

    Sandra Montserrat Nájera-Villagrana; Armando Reyes-Cadena; Angélica León-Hernández

    2014-01-01

    The Johanson-Blizzard syndrome is an autosomal recessive disease characterized by aplasia or hypoplasia of the wings of the nose, exocrine pancreatic insufficiency, hypothyroidism, dental abnormalities and mental retardation. There are fewer than 100 cases reported in the literature worldwide. We document the case of a girl with all the features of the Johanson-Blizzard syndrome, in order to facilitate its early recognition and anticipate the serious problems associated. Cur...

  9. Adsorption of Polyether Block Copolymers at Silica-Water and Silica-Ethylammonium Nitrate Interfaces.

    Science.gov (United States)

    Chen, Zhengfei; Kobayashi, Yumi; Webber, Grant B; Ueno, Kazuhide; Watanabe, Masayoshi; Warr, Gregory G; Atkin, Rob

    2015-06-30

    Atomic force microscope (AFM) force curves and images are used to characterize the adsorbed layer structure formed by a series of diblock copolymers with solvophilic poly(ethylene oxide) (PEO) and solvophobic poly(ethyl glycidyl ether) (PEGE) blocks at silica-water and silica-ethylammoniun nitrate (EAN, a room temperature ionic liquid (IL)) interfaces. The diblock polyethers examined are EGE109EO54, EGE113EO115, and EGE104EO178. These experiments reveal how adsorbed layer structure varies as the length of the EO block varies while the EGE block length is kept approximately constant; water is a better solvent for PEO than EAN, so higher curvature structures are found at the interface of silica with water than with EAN. At silica-water interfaces, EGE109EO54 forms a bilayer and EGE113EO115 forms elongated aggregates, while a well-ordered array of spheres is present for EGE104EO178. EGE109EO54 does not adsorb at the silica-EAN interface because the EO chain is too short to compete with the ethylammonium cation for surface adsorption sites. However, EGE113EO115 and EGE104EO178 do adsorb and form a bilayer and elongated aggregates, respectively.

  10. The Unified State Exam in Russia: Problems and Perspectives

    OpenAIRE

    Denisova-Schmidt, Elena; Leontyeva, Elvira

    2014-01-01

    Since 2009, all Russian students have had to pass the EGE (Unified State Exam), which serves as both school finals and university entrance examinations. The EGE was planned as an efficient instrument to counter corruption in university admission and to promote student mobility. Since its inception, the EGE has only fulfilled half of these goals: while mobility has increased significantly, corruption persists. The paper explains some of the reasons for this. [http://ejournals.bc.edu/ojs/in...

  11. Pametno zaznavalo pospeška

    OpenAIRE

    Plavčak, Lotti

    2017-01-01

    Diplomsko delo obravnava konfiguracijo in uporabo tako imenovanih pametnih MEMS zaznaval na področju merjenja nihanj. V diplomskem delu je predstavljen postopek nadgradnje MEMS pospeškomera ADXL, s pomočjo Adafruit Feather HUZAHH ESP8266 mikrokrmilnika. Prav tako je opisan celoten postopek pisanja programske kode, ki omogoča komunikacijo pospeškomera z uporabnikom. V nadaljevanju diplomske naloge je predstavljen uporabniški vmesnik, ki omogoča nastavitev časovnega okna zajemanja in izris merj...

  12. Uued agulimajad = New Suburb Houses / Andri Ksenofontov

    Index Scriptorium Estoniae

    Ksenofontov, Andri, 1962-

    2005-01-01

    Tallinna ajalooliste eeslinnade teke ja kujunemine. Agulite olukord tänapäeval ja haldus viimastel aastatel. Büroo 3+1 projekteeritud ühepereelamu Magasini kvartalis (arhitektid Andres Ojari, Markus Kaasik, Ilmar Valdur, Merje Müürisepp, Kalle Komissarov). Neljakorruseline elamu Õle t. 23/Härjapea t. 14, ühtlasi arhitektide Madis Eegi ja Margit Mutso kodu. Gert Sarve projekteeritud kahepereelamu Herne t. 9. KOKO arhitektide Raivo Kotovi ja Tõnis Kimmeli projekteeritud korterelamu Vabriku t. 33. Ill.: 12 plaani, 14 värv. vaadet

  13. Merging Grid Technologies

    NARCIS (Netherlands)

    Begeman, K. G.; Belikov, A. N.; Boxhoorn, D. R.; Dijkstra, F.; Valentijn, E. A.; Vriend, W. -J.; Zhao, Z.

    This paper reports the integration of the astronomical Grid solution realised in the Astro-WISE information system with the EGEE Grid and the porting of Astro-WISE applications on EGEE. We review the architecture of the Astro-WISE Grid, define the problems for the integration of the Grid

  14. Mechanisms underlying the endothelium-dependent vasodilatory ...

    African Journals Online (AJOL)

    Relaxations to EGE were abolished by the membrane permeant, SOD mimetic, MnTMPyP, and significantly reduced by wortmannin, an inhibitor of PI3-kinase. Exposure of endothelial cells to EGE increased the phosphorylation level of eNOS at Ser1177 in a time and concentration-dependent manner. MnTMPyP abolished ...

  15. Degradation of soil physicochemical quality by ephemeral gully erosion on sloping cropland of the hilly Loess Plateau, China

    Science.gov (United States)

    Ephemeral gully erosion (EGE) is a common type of shallow linear erosion that exerts a major threat to the productivity and sustainability of agricultural systems. The objective was to evaluate the impact of EGE on soil physicochemical properties that determine soil quality. It was hypothesized that...

  16. Key European Grid event to take place in Geneva

    CERN Multimedia

    2006-01-01

    EGEE'06 is the main conference of the EGEE project, which is co-funded by the European Union and hosted by CERN. More than 90 partners all over Europe and beyond are working together in EGEE to provide researchers in both academia and industry with access to major computing resources, independent of their geographic location. The largest user community of the EGEE Grid is the High-Energy Physics community and in particular the LHC experiments, which are already making heavy use of the infrastructure to prepare for data taking. However, with the many new challenges faced by EGEE in its second phase that started in April this year, an even broader audience than at previous EGEE conferences is expected. In particular, a large number of related Grid projects will feature prominently in both plenary and parallel sessions during the 5 days of this event. Industry will also be well represented, highlighting the EGEE project's commitment to technology transfer to industry. CERN is the host of the conference, which i...

  17. Disease: H00571 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available le J, Song HK, Varshavsky A, Zenker M Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndrome. PLoS One 6:e24925 (2011) ...

  18. The Effect of Prolonged Military Activities in Man. Physiological and Biochemical Changes. Possible Means of Rapid Recuperation (les Effets d’activites mi1itaires prolongees sur l’homme. Changements physiologiques et biochimiques. Moyens possibles de recuperation rapide.)

    Science.gov (United States)

    2001-03-01

    adrenals, ovaries, uterus, placenta, testis, prostate, 1-18 seminal vesicles, Leydig cells, hypothalamus, choroid plexus , pancreatic islets, lymphoid tissue...Proceedings of the AC 243/Panel 8 (RSG 23) Meeting, The Hague, May 7-8th, 4.2.1-12 Dahlgren C, Follin F, Johanson A, Lock R, Lundqvist H, Walan Å (1991

  19. A New Vision for Public Art and Functional Landscape Design

    Science.gov (United States)

    Song, Young Imm Kang

    2014-01-01

    This article explores how Johanson's ecological public art and landscape design addresses current social issues and community necessities. It also examines how her designs may serve as a communication tool for the surrounding society, and how her public art may provide new perspectives for community members, scientists, artists, engineers,…

  20. Kus ta siis ometi on - see Bob Dylan? / Immo Mihkelson

    Index Scriptorium Estoniae

    Mihkelson, Immo, 1959-

    2008-01-01

    Todd Haynes'i mängufilm muusik Bob Dylanist "Kus on Bob Dylan?" ("I'm Not There") : laulja alter ego kehastavad Ben Whishaw, Christian Bale, Heath Ledger, Cate Blanchett, Richard Gere, Marcus Carl Franklin : Ameerika Ühendriigid 2007. 4. juunil Saku Suurhallis toimuvast kontserdist. Jaak Johanson, Tõnis Mägi, Riho Sibul, Hannes Varblane ameerika lauljast

  1. Eliel Saarineni Suur-Tallinna kavand / Dmitri Bruns

    Index Scriptorium Estoniae

    Bruns, Dmitri, 1929-

    2004-01-01

    Tallinna generaalplaani saamiseks 1913. a. korraldatud rahvusvahelisel konkursil anti I preemia projektile "Kolm lõvi", mille autoriks oli soome arhitekt Eliel Saarinen. Soovitati osta projekt "Kern", mille autoriteks olid C. Johanson ja A. Lindgren. E. Saarinenist, tema linnaehituslikest tõekspidamistest ja Suur-Tallinna projektist. Järgneb nr. 6, lk. 73-75

  2. Kontserdisari "Rosaarium" alustab Jänedal

    Index Scriptorium Estoniae

    2009-01-01

    Kontserdisari "Rosaarium" alustab kolmandat hooaega, kontsertidest Jäneda mõisa roosiaias: 27. juunil esinevad laulja Hanna-Liina Võsa ja pianist Olav Ehala, 1. augustil Riho Sibul, Mirjam Dede ja Tõrva Laulustuudio neidudekoor dirigent Maie Kala juhendamisel, 21. augustil Jaak Johanson ja Virumaa Poistekoor Elo Forseli juhendamisel ning Virumaa Noorte Meeskoor Andrus Siimoni juhendamisel

  3. Investigation of Effect of KBr Matrix on Drift Infrared Spectra of Some ...

    African Journals Online (AJOL)

    MBI

    2014-09-28

    Sep 28, 2014 ... analysing samples without any interference through sample preparation (Frost and Johanson, 1998.) Samples can be analysed by diffuse reflectance infrared Fourier transform (DRIFTS) spectroscopy, in the form of undiluted or neat powders with very little preparation. However, spectra can be affected.

  4. Maalehe Raamatu aiaabi

    Index Scriptorium Estoniae

    2007-01-01

    Tallinnas 2006. a. ilmunud raamatust "Praktiline aiarajaja käsiraamat" (toimetaja Deborah Parker, peatoimetaja Christopher Brickell), Herman Hacksteini ja Wota Wehmeyeri "Kiviktaimlaleksikonist" (toimetaja Riina Tammsaar), 2007. a. ilmunud Börje Erikssoni ja Pär Schyllanderi raamatust "Veekogud aias" (toimetajad R. Tammsaar ja Signe Siim, fotod: Bertil K. Johanson), Bertil K. Johansoni raamatust "Aialilled" (toimetaja R. Tammsaar)

  5. Linnateatri impro toob lavale eesti tööjõu Iirimaal / Kristi Eberhart

    Index Scriptorium Estoniae

    Eberhart, Kristi

    2005-01-01

    J. Rohumaa lavastus "Impro 3 - Punane Hanrahan" Tallinna Linnateatris. Tükk põhineb B. Yeatsi jutustustel Punase Hanrahani nimelisest rändlaulikust, iiri muinasjuttudel ja ning trupi enda lugudel ja improvisatsioonil. Kaasa teevad muusikutena Dave Murphy Iirimaalt ja Jaak Johanson. Esietendus 21. mail

  6. Jaanus Rohumaa toob välja iiri impro

    Index Scriptorium Estoniae

    2005-01-01

    21. mail esietendub Tallinna Linnateatris J. Rohumaa lavastus "Impro 3 - Punane Hanrahan". Tükk põhineb B. Yeatsi jutustustel Punase Hanrahani nimelisest rändlaulikust, iiri muinasjuttudel ja ning trupi enda lugudel ja improvisatsioonil. Kaasa teevad muusikutena Dave Murphy Iirimaalt ja Jaak Johanson

  7. Jaanus Rohumaa : impro on avatud ja rõõmus teater / Jaanus Rohumaa ; interv. Kristi Eberhart

    Index Scriptorium Estoniae

    Rohumaa, Jaanus, 1969-

    2005-01-01

    21. mail esietendub Tallinna Linnateatris J. Rohumaa lavastus "Impro 3 - Punane Hanrahan". Tükk põhineb B. Yeatsi jutustustel Punase Hanrahani nimelisest rändlaulikust, iiri muinasjuttudel ja ning trupi enda lugudel ja improvisatsioonil. Kaasa teevad muusikutena Dave Murphy Iirimaalt ja Jaak Johanson

  8. correlation studies and path coefficient analysis for seed yield and ...

    African Journals Online (AJOL)

    Prof. Adipala Ekwamu

    Phenotypic and genotypic correlation coefficients were estimated according to. Johanson et al. (1955), Miller et al. (1958) and. Singh and Chavdhury (1985). Where: = Phenotypic correlation coefficient between traits x and y; ..... Robert E. Kinger Publishing Company,. Malabar. 427pp. Gurubuz, B. 2001. Correlation and path ...

  9. Siidii / Annika Koppel

    Index Scriptorium Estoniae

    Koppel, Annika

    2003-01-01

    Heliplaatidest: Millenia Nova "Narcotic Wide Screen Vista", Trygve Seim "Different Rivers", Eesti Keeled ja Jaak Johanson, Riho Sibul "Sabaga Täht", Peeter Vähi, Fedor Vetkalov, Dmitri Tkachenko "Best Regards From Tallinn And Moscow", Brainstorm "A Day Before Tomorrow", Allegri, Pärt, Tormis "Light"

  10. Millised liitvalla piirkonnad hakkavad teiste üle domineerima?

    Index Scriptorium Estoniae

    2005-01-01

    Küsimusele vastavad: Vello Lattik, Priit Toobal, Heldur Kraaner (Keskerakond), Are Aua (Olustvere Valla Ühendus), Ülo Köst, Enno Püvi (Reformierakond), Aivar Paas, Aivar Siim (Isamaaliit), Maie Käba (Koduvald), Rünno Johanson (Rahvaliit) ja Lembit Kruuse (Res Publica). Üles kirj. Rannar Raba

  11. Jevropeiskii Sojuz otmenjajet bankovskuju tainu / Ljudmila Shorikova

    Index Scriptorium Estoniae

    Shorikova, Ljudmila

    2003-01-01

    Alates uuest aastast kaob Euroopa Liidu pangandusest mõiste pangasaladus - välisriigis hoiuse omajad peavad maksma tulumaksu pangaintressilt, maksuametid vahetavad infot hoiustajate kohta, keelatud on omada anonüümset hoiust. Saavutatud kokkulepped EL-i riikide vahel ei rahuldanud Luksemburgi, Austriat ja Šveitsi. Kommenteerivad Silver Võhu ja Kristel Johanson

  12. „EU”: short for „ethical” union? The role of ethics in European Union law / Markus Frischhut

    Index Scriptorium Estoniae

    Frischhut, Markus

    2015-01-01

    Eetika ja moraali põhimõtetest ELi esmases ja teiseses õiguses ning institutsioonide tegevuses; Euroopa Kohtu praktikast ning Teaduse ja uute tehnoloogiate eetika Euroopa töörühma (EGE) hinnangutest

  13. Eosinophilic Gastroenteritis as a Rare Cause of Recurrent Epigastric Pain

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Safari

    2016-04-01

    Full Text Available Eosinophilic gastroenteritis (EGE is a rare inflammatory disorder of gastrointestinal tract characterized by eosinophilic infiltration of the bowel wall. It can mimic many gastrointestinal disorders due to its wide spectrum of presentations. Diagnose is mostly based on excluding other disorders and a high suspicion. Here we report a case of 26 year old man with a history of sever epigastric pain followed by nausea, vomiting since a few days before admission with final diagnosis of EGE.

  14. Eosinophilic Gastroenteritis as a Rare Cause of Recurrent Epigastric Pain

    Science.gov (United States)

    Safari, Mohammad Taghi; Shahrokh, Shabnam; Miri, Mohammad Bagher; Ehsani Ardakani, Mohammad Javad

    2016-01-01

    Eosinophilic gastroenteritis (EGE) is a rare inflammatory disorder of gastrointestinal tract characterized by eosinophilic infiltration of the bowel wall. It can mimic many gastrointestinal disorders due to its wide spectrum of presentations. Diagnose is mostly based on excluding other disorders and a high suspicion. Here we report a case of 26 year old man with a history of sever epigastric pain followed by nausea, vomiting since a few days before admission with final diagnosis of EGE. PMID:27274524

  15. Mechanisms underlying the endothelium-dependent vasodilatory effect of an aqueous extract of Elaeis Guineensis Jacq. (Arecaceae) in porcine coronary artery rings.

    Science.gov (United States)

    Ndiaye, Mamadou; Anselm, Eric; Séne, Madièye; Diatta, Williams; Dièye, Amadou Moctar; Faye, Babacar; Schini-Kerth, Valérie B

    2009-12-30

    This study was undertaken to investigate the vasodilatory effect of an aqueous extract of Elaeis guineensis Jacq (EGE) in the porcine coronary artery and elicit its possible mechanism(s) of action. Vascular effects of crude extract of dried and powdered leaves of Elaeis guineensis were evaluated on isolated coronary arteries on organ chambers. Determination of eNOS expression and the phosphorylation level of eNOS were determined by Western blot analysis. In the presence of indomethacin, EGE caused pronounced relaxations in endothelium-intact but not in endothelium-denuded coronary artery rings. Relaxations to EGE were significantly reduced by N(ω)-nitro-L-arginine (L-NA, a competitive inhibitor of NO synthase), slightly but not significantly by charybdotoxin plus apamin (two potent inhibitors of EDHF-mediated responses) and abolished by the combination of L-NA and charybdotoxin plus apamin. Relaxations to EGE were abolished by the membrane permeant, SOD mimetic, MnTMPyP, and significantly reduced by wortmannin, an inhibitor of PI3-kinase. Exposure of endothelial cells to EGE increased the phosphorylation level of eNOS at Ser1177 in a time and concentration-dependent manner. MnTMPyP abolished the EGE-induced phosphorylation of eNOS.In conclusion, the obtained data indicate that EGE induces pronounced endothelium-dependent relaxations of the porcine coronary artery, which involve predominantly NO. The stimulatory effect of EGE on eNOS involves the redox-sensitive phosphorylation of eNOS at Ser1177 most likely via the PI3-kinase pathway.

  16. Sığacık Körfezi'nde (Ege Denizi Bulunan İki Tür Köpekbalığının [Galeus melastomus Rafinesque, 1810 ve Squalus blainvillei (Risso, 1826] Boy-Ağırlık İlişkisi ve Beslenme Özellikleri Üzerine Bir Ön Çalışma.

    Directory of Open Access Journals (Sweden)

    Şebnem Özütemiz

    2015-12-01

    Full Text Available Bu çalışmada, Sığacık Körfezi’nde dağılım gösteren Galeus melastomus Rafinesque, 1810 ve Squalus blainvillei (Risso, 1826 türlerinin bazı büyüme ve beslenme özellikleri tespit edilmiştir. Galeus melastomus türü için toplam 130 (59♂, 51♀, 20 juvenil birey incelenmiş ve türün minimum, maximum ve ortalama total boyları sırasıyla 9 cm, 19 cm ve 14,01 cm (±1,96 olarak bulunmuştur. Minimum, maximum ve ortalama ağırlıkları ise sırasıyla 2,92 g, 22,67 g ve 8,46 g (±4,03 aralığındadır. Squalus blainvillei türü için 135 (57♂, 78♀ birey incelenmiş ve türün minimum, maximum ve ortalama total boyları sırasıyla 16 cm, 28 cm ve 21,46 cm (±2,21 olarak bulunmuştur. Minimum, maximum ve ortalama ağırlıkları ise sırasıyla 18,64 g, 95,92 g ve 45,64 g (±15,97 aralığındadır. Mideleri incelenen 2 tür köpekbalığının da başlıca besinini Crustacea türleri oluşturmaktadır. Bunu takip eden diğer besin grupları sırası ile Teleostei ve Cephalopoda türleridir

  17. Obesity and the Endometrium: Adipocyte-Secreted Proinflammatory TNFα Cytokine Enhances the Proliferation of Human Endometrial Glandular Cells

    Directory of Open Access Journals (Sweden)

    Sangeeta Nair

    2013-01-01

    Full Text Available Obesity, a state of chronic inflammation, is associated with poor fertility and low implantation rates and is a well-documented risk factor for endometrial cancer. Adipokines, such as tumor necrosis factor alpha, play an important role in initiation of endometrial cancer. The aim of this study is to evaluate in vitro effects of human adipocyte cells (SW872 on growth of endometrial glandular epithelial cells (EGE. Methods. We measured cell proliferation and expression of cell-growth proteins—proliferating cell nuclear antigen, cyclin D1, cyclin-dependent kinase-1, and apoptotic markers (BCL-2 and BAK in human EGE cells cocultured with SW872 cells. EGE cells were also evaluated in SW872-conditioned media neutralized with anti-TNFα antibody. Results. A significant increase in EGE cell proliferation was observed in both SW872-conditioned media and in coculture (P<0.05. We observed an upregulation of proliferation markers PCNA, cyclin D1, CDK-1, and BCL-2 and decrease in BAK (P<0.05. Neutralization of SW872-conditioned media using anti-TNFα antibodies reversed EGE cell proliferation as indicated by BCL-2 expression. Conclusions. Adipocytes have potent proliferative paracrine effect on EGE cells which may be, in part, mediated via TNFα. Further understanding of the role of obesity in endometrial carcinogenesis should lead to better preventative and therapeutic strategies.

  18. Lugemist vihmasteks päevadeks / Jaan Mettik

    Index Scriptorium Estoniae

    Mettik, Jaan

    2006-01-01

    2006. a. Tallinnas kirjastuselt "Varrak" ilmunud Penelope Hobhouse raamatust "Aianduse ajalugu", kirjastuselt "Maalehe Raamat" ilmunud Susanna Widlundhi raamatust "Kaunid kõrrelised", Lena Manssoni raamatust "Suvelilled. Muuda igal aastal oma aia välimust" ja Inger Palmistierna raamatust "Puud ja põõsad aias" (3 raamatu fotod: Bertil K. Johanson), kirjastuselt "Tänapäev" ilmunud Brent Elliotti raamatust "Floora : aialillede illustreeritud ajalugu"

  19. Zrożnicowanie plio-plejstoceńskich Hominidae III. Konsekwencje taksonomiczne i antropogenetyczne

    OpenAIRE

    Kaszycka, Katarzyna

    1986-01-01

    This work presents the final part of a cycle of articles among which the two latter ones discussed the morphology, ecology and sexual dimorphism of early hominids called Australopithecines. The present part evaluates two different interpretations of hominid phylogeny: multi-species hypothesis and the single species one. The proposals of R. Broom; Louis, Mary and Richard Leakey; J. Robinson, D. Pilbeam and M. Zwell; and D. Johanson and T. White have been discussed. Attention has been ...

  20. H. Hiibuse šarž Oskar Lutsust (1986) : [eriväljaanne Oskar Lutsust

    Index Scriptorium Estoniae

    1987-01-01

    Fotod ; O. Luts 1903.a. ; Eduard Jürgenson ja Oskar Lutsu sõjaväefarmatseutidena 1911.a. ; Valentina, Georg ja Oskar Luts 1923.a. ; O. Lutsu õhtu ÜENÜTO-s 1927.a. ; O. Luts, A. Leetva-Müür, A. Mering ja A. Johanson ning V. Vent ; O. Luts, J. Aavik ja M. Nurmik 1922.a. Haapsalus ; O. Luts ja J. Sisask 1930-ndate aastate alguses

  1. The man and the stars

    Science.gov (United States)

    Serban, Mihai E.

    1986-02-01

    The book concerns the history and the evolution of the Universe. It Concerns also to Space era, the history of the biological life on the Earth. The author is presenting his own evolutional point of view. He also is citting a number of important archeological sources, including the discovery by Taieb and Johanson of the skeleton "Lucy", the dissaperence of Dinosaurs, the concept of Panspermia

  2. Võidukad kirjutajad

    Index Scriptorium Estoniae

    2007-01-01

    Eduard Vilde muuseumi poolt läbi viidud krimi- ja põnevusjuttude võistlusest "Musta mantliga mees". Võitja: Katrin Johanson, teine koht: Taavet Kase, kolmas koht: Imre Kõuts. Ajalehe "Postimees" eriauhinnad said: Juhan Voolaid, Hella Riisalu, Stina Maria Vilt, Sirle Poikkanen, Märt Kivimäe. Tallinna noorte infokeskuse auhind: Aino Rätsep. Eduard Vilde muuseumi eriauhinnad: Merilin Jürjo, Laura Pirso

  3. Veerenni asumi süda oli Lutheri vabrik / Robert Nerman

    Index Scriptorium Estoniae

    Nerman, Robert, 1946-2015

    2008-01-01

    Tallinna kesklinnas Pärnu maantee, Tallinn-Narva raudtee ja Siselinna kalmistu vahel asuva piirkonna ajaloost. Lutheri puidutööstuse rajamisest. Hooned projekteeris arhitekt Erwin Bernhard. Juugendstiilis rahvamaja arhitektid olid Herman Gesellius, Armas Lindgren ja Eliel Saarinen. Keskhaigla töötajatele Herne tänavale rajatud elamute ning Tallinna Ühisgümnaasiumi hoone arhitekt oli Herbert Johanson

  4. The Propensity To Continue Service Internationalization - A Model Of Planned Behavior

    OpenAIRE

    Wetzels, Martin; de Ruyter, Ko; Patterson, Paul G.; Pauwels, Pieter

    2003-01-01

    The present study investigates the propensity to continue internationalization by experienced international service providers. Enhancing the cognitive-behavioral root of internationalization process theory (Johanson and Vahlne 1977; 1990), this paper builds upon Ajzen’s (1991) theory of planned behavior. Consistent with the latter theory, the propensity to continue service internationalization is modelled as behavioral intention that results from (1) an overall attitude towards internationali...

  5. Appearance of microvascular obstruction on high resolution first-pass perfusion, early and late gadolinium enhancement CMR in patients with acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Redwood Simon

    2009-08-01

    Full Text Available Abstract Background The presence and extent of microvascular obstruction (MO after acute myocardial infarction can be measured by first-pass gadolinium-enhanced perfusion cardiovascular magnetic resonance (CMR or after gadolinium injection with early or late enhancement (EGE/LGE imaging. The volume of MO measured by these three methods may differ because contrast agent diffusion into the MO reduces its apparent extent over time. Theoretically, first-pass perfusion CMR should be the most accurate method to measure MO, but this technique has been limited by lower spatial resolution than EGE and LGE as well as incomplete cardiac coverage. These limitations of perfusion CMR can be overcome using spatio-temporal undersampling methods. The purpose of this study was to compare the extent of MO by high resolution first-pass k-t SENSE accelerated perfusion, EGE and LGE. Methods 34 patients with acute ST elevation myocardial infarction, treated successfully with primary percutaneous coronary intervention (PPCI, underwent CMR within 72 hours of admission. k-t SENSE accelerated first-pass perfusion MR (7 fold acceleration, spatial resolution 1.5 mm × 1.5 mm × 10 mm, 8 slices acquired over 2 RR intervals, 0.1 mmol/kg Gd-DTPA, EGE (1–4 minutes after injection with a fixed TI of 440 ms and LGE images (10–12 minutes after injection, TI determined by a Look-Locker scout were acquired. MO volume was determined for each technique by manual planimetry and summation of discs methodology. Results k-t SENSE first-pass perfusion detected more cases of MO than EGE and LGE (22 vs. 20 vs. 14, respectively. The extent of MO imaged by first-pass perfusion (median mass 4.7 g, IQR 6.7 was greater than by EGE (median mass 2.3 g, IQR 7.1, p = 0.002 and LGE (median mass 0.2 g, IQR 2.4, p = 0.0003. The correlation coefficient between MO mass measured by first-pass perfusion and EGE was 0.91 (p Conclusion The extent of MO following acute myocardial infarction appears larger on

  6. Appearance of microvascular obstruction on high resolution first-pass perfusion, early and late gadolinium enhancement CMR in patients with acute myocardial infarction.

    Science.gov (United States)

    Mather, Adam N; Lockie, Timothy; Nagel, Eike; Marber, Michael; Perera, Divaka; Redwood, Simon; Radjenovic, Aleksandra; Saha, Ansuman; Greenwood, John P; Plein, Sven

    2009-08-21

    The presence and extent of microvascular obstruction (MO) after acute myocardial infarction can be measured by first-pass gadolinium-enhanced perfusion cardiovascular magnetic resonance (CMR) or after gadolinium injection with early or late enhancement (EGE/LGE) imaging. The volume of MO measured by these three methods may differ because contrast agent diffusion into the MO reduces its apparent extent over time. Theoretically, first-pass perfusion CMR should be the most accurate method to measure MO, but this technique has been limited by lower spatial resolution than EGE and LGE as well as incomplete cardiac coverage. These limitations of perfusion CMR can be overcome using spatio-temporal undersampling methods. The purpose of this study was to compare the extent of MO by high resolution first-pass k-t SENSE accelerated perfusion, EGE and LGE. 34 patients with acute ST elevation myocardial infarction, treated successfully with primary percutaneous coronary intervention (PPCI), underwent CMR within 72 hours of admission. k-t SENSE accelerated first-pass perfusion MR (7 fold acceleration, spatial resolution 1.5 mm x 1.5 mm x 10 mm, 8 slices acquired over 2 RR intervals, 0.1 mmol/kg Gd-DTPA), EGE (14 minutes after injection with a fixed TI of 440 ms) and LGE images (1012 minutes after injection, TI determined by a Look-Locker scout) were acquired. MO volume was determined for each technique by manual planimetry and summation of discs methodology. k-t SENSE first-pass perfusion detected more cases of MO than EGE and LGE (22 vs. 20 vs. 14, respectively). The extent of MO imaged by first-pass perfusion (median mass 4.7 g, IQR 6.7) was greater than by EGE (median mass 2.3 g, IQR 7.1, p = 0.002) and LGE (median mass 0.2 g, IQR 2.4, p = 0.0003). The correlation coefficient between MO mass measured by first-pass perfusion and EGE was 0.91 (p < 0.001). The extent of MO following acute myocardial infarction appears larger on high-resolution first-pass perfusion CMR than on

  7. THE INDICES OF EXAMINATION TEXTS COMPLEXITY

    Directory of Open Access Journals (Sweden)

    Solnyshkina Marina Ivanovna

    2015-03-01

    Full Text Available The article presents the results of the analysis aimed at quantitative (word length and sentence length and qualitative (narrativity, syntactic simplicity, word concreteness, referential cohesion and deep cohesion characteristics used in Flesh Reading Ease and Coh-Metrix to determine complexity/simplicity of FCE and EGE examination texts corresponding to B2 level by Common European Framework of References. The data used in the research include18 examination texts of three language tests analogous in structure and content: in Russian (Test of Russian as a Foreign Language and in English (Unified (Russia State Examination in English (EGE and First Certificate Examination (FCE. Flesch Reading Ease indices of all the Russian texts analyzed testify to their higher level of complexity than the announced in the corresponding papers (B2. The English texts correspond to the Level B2 by CEFR. The computerized with Coh-Metrix texts utilized in EGE and FCE prove to belong to B2 level, though the EGE texts demonstrate on average higher than FCE texts levels of concreteness but lower levels of syntactic simplicity. Maintaining approximately equal levels of concreteness EGE and FCE texts obtain about the same levels of complexity (B2 due to the differences in the number of verbalized local and global content links. Thus, the Russian test developers model the authentic English texts for examination purposes eliminating the connectives and verbalizing referential and deep cohesion.

  8. Efficacy of Dietary Treatment for Inducing Disease Remission in Eosinophilic Gastroenteritis.

    Science.gov (United States)

    Lucendo, Alfredo J; Serrano-Montalbán, Beatriz; Arias, Ángel; Redondo, Olga; Tenias, José M

    2015-07-01

    Various dietary interventions have been used to treat patients with eosinophilic gastroenteritis (EGE). Concrete evidence as to the effectiveness of such treatments in inducing disease remission is, however, lacking. The aim of the study was to systematically review the efficacy of dietary therapies in inducing EGE remission. We performed a systematic search for the MEDLINE, EMBASE, and SCOPUS libraries for studies investigating the efficacy of dietary interventions (in both histological and symptomatic remission) for children and adults with EGE and colitis. The search yielded 490 references; 30 were included in the review, with most of these references being "low-quality" individual cases or short case series. No significant publication bias was found. Elemental diets in children were linked to 75.8% of clinical improvement, but few of these patients underwent a histological evaluation. Allergy-testing results have been used scarcely in EGE. Empiric elimination of allergy-associated foods was the most commonly used option. The variable results in terms of symptom relief, however, were scarcely accompanied by histological confirmation. Clinical and methodological heterogeneity hindered the performance of quantitative summaries for the efficacy of dietary therapies in inducing disease remission. Symptomatic improvements reported for dietary treatment in EGE by most of the available literature are questionable because of the lack of objective evaluation of clinical changes and the very limited assessment of histological remission. Because of the relative lack of well-designed, high-quality studies, the unequivocal use of dietary treatment for patients with EGE and colitis cannot be supported. Further research should be undertaken.

  9. Page | 170

    African Journals Online (AJOL)

    Fr. Ikenga

    situation Idoma women find themselves using the Idoma dialect that ege lotu chanya geni,njegede nlotu ..... The Pagan Arabs considered women as chattels to be inherited or disposed of at the whims of the male ..... the verse within the Qur'anic framework, Abu Sulayman concludes that the Arabic word “daraba” does not ...

  10. Enterprise grid and the future of IT

    CERN Multimedia

    2007-01-01

    Interview with Rolf Kubli, a fellow of EDS, a Switzerland-based technology services company and CERN openlab contributors, previews his presentation at this week's OGF20/EGEE User Forum event and shares his thoughts on its theme" "Beliefs about the future of IT and how they relate to the enterprise grid vision. (2,5 pages)

  11. Racial differences in eosinophilic gastrointestinal disorders among Caucasian and Asian

    Directory of Open Access Journals (Sweden)

    Jun Ito

    2015-07-01

    Conclusions: We found that EoE occurs more frequently in Caucasian EGID patients than Asian EGID patients, while the reverse is true for EGE. Also, racial disparities in symptoms and eosinophil-infiltrated tissues were observed. Our findings suggest further genetic and environmental studies to elucidate the etiology of EGID.

  12. The Leisure Behavior of the Turkish Prospective Teachers

    Science.gov (United States)

    Aslan, Nese; Cansever, Belgin Arslan

    2016-01-01

    This study focused on prospective teachers' leisure behaviors. For this purpose, 47 fourth grade undergraduate students in Faculty of Education in Ege University, Izmir, Turkey participated. A qualitative research design was used in the study. In the process of analysing the data, Greimas' Actant Model as one of the analysing models in Semiology…

  13. Data of evolutionary structure change: 1EGEC-1SIRA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EGEC-1SIRA 1EGE 1SIR C A -------LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWE...1SIR A 1SIRA MSVQSSLVMHP ...1SIR A 1SIRA RAHYNSSNKSYT...1SIR A 1SIRA LGPTI-KGYGC ...1SIR A 1SIRA PGASS-LGGPF

  14. Data of evolutionary structure change: 1EGEB-1SIRA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1EGEB-1SIRA 1EGE 1SIR B A -------LGFSFEFTEQQKEFQATARKFAREEIIPVAAEYDKTGEYPVPLIRRAWE...1SIR A 1SIRA MSVQSSLVMHP ...1SIR A 1SIRA RAHYNSSNKSYT...1SIR A 1SIRA LGPTI-KGYGC ...1SIR A 1SIRA PGASS-LGGPF

  15. Shadows behind the computers

    CERN Multimedia

    CERN audiovisual service; Jacques Fichet

    2007-01-01

    EGEE organized a shadowing day to spur female students to take up careers in the IT field. Eleven female staff from CERN’s IT Department were kept under close surveillance last week, shadowed by female students from the Collège du Léman International School as part of the Enabling Grids for E-sciencE project Gender Action Plan.

  16. Assessing the toxic effects of ethylene glycol ethers using Quantitative Structure Toxicity Relationship models.

    Science.gov (United States)

    Ruiz, Patricia; Mumtaz, Moiz; Gombar, Vijay

    2011-07-15

    Experimental determination of toxicity profiles consumes a great deal of time, money, and other resources. Consequently, businesses, societies, and regulators strive for reliable alternatives such as Quantitative Structure Toxicity Relationship (QSTR) models to fill gaps in toxicity profiles of compounds of concern to human health. The use of glycol ethers and their health effects have recently attracted the attention of international organizations such as the World Health Organization (WHO). The board members of Concise International Chemical Assessment Documents (CICAD) recently identified inadequate testing as well as gaps in toxicity profiles of ethylene glycol mono-n-alkyl ethers (EGEs). The CICAD board requested the ATSDR Computational Toxicology and Methods Development Laboratory to conduct QSTR assessments of certain specific toxicity endpoints for these chemicals. In order to evaluate the potential health effects of EGEs, CICAD proposed a critical QSTR analysis of the mutagenicity, carcinogenicity, and developmental effects of EGEs and other selected chemicals. We report here results of the application of QSTRs to assess rodent carcinogenicity, mutagenicity, and developmental toxicity of four EGEs: 2-methoxyethanol, 2-ethoxyethanol, 2-propoxyethanol, and 2-butoxyethanol and their metabolites. Neither mutagenicity nor carcinogenicity is indicated for the parent compounds, but these compounds are predicted to be developmental toxicants. The predicted toxicity effects were subjected to reverse QSTR (rQSTR) analysis to identify structural attributes that may be the main drivers of the developmental toxicity potential of these compounds. Copyright © 2010. Published by Elsevier Inc.

  17. Shining examples of grid applications

    CERN Multimedia

    Hammerle, Hannelore

    2006-01-01

    Users in more than 150 virtual organisations from fields as diverse as biomedicine, earth Sciences and high-energy physics are now using the distributed computing infrastructure of the enabling grids for E-sciencE (EGEE) project, which shows the wide adoption and versatiblity of this new technology (1 page)

  18. The two major Grid infrastructures

    CERN Multimedia

    2005-01-01

    This map shows the world's two major Grid infrastructures. The Open Science Grid (OSG) will handle data in the US, while Enabling Grids for E-sciencE (EGEE) will process data in Europe and the rest of the world. These Grids share processing power in order to process the huge amounts of information from experiments such as those at the LHC.

  19. A virtual laboratory for medical image analysis

    NARCIS (Netherlands)

    Olabarriaga, Sílvia D.; Glatard, Tristan; de Boer, Piter T.

    2010-01-01

    This paper presents the design, implementation, and usage of a virtual laboratory for medical image analysis. It is fully based on the Dutch grid, which is part of the Enabling Grids for E-sciencE (EGEE) production infrastructure and driven by the gLite middleware. The adopted service-oriented

  20. No increased susceptibility to breast cancer from combined CHEK2 1100delC genotype and the HLA class III region risk factors

    NARCIS (Netherlands)

    de Jong, Mirjam; Nolte, Ilja; te Meerman, Gerhardus; van der Graaf, WTA; Oosterom, E; Bruinenberg, M; van der Steege, G; Oosterwijk, JC; van der Hout, Annemarie; Boezen, HM; Schaapveld, M; Kleibeuker, JH; de Vries, EGE

    CHEK2 is low-penetrance breast cancer susceptibility gene. The 1100delC mutation may interact with variants/mutations in other breast cancer susceptibility loci. We identified a risk haplotype in the HLA class III region in breast cancer patients [de Jong MM, Nolte IM, de Vries EGE, et al. The HLA

  1. Elemental Analysis of Galium incanum SM subsp Centrale Ehrend ...

    African Journals Online (AJOL)

    Herbarium of Pharmacognosy Department,. Faculty of Pharmacy, Ege University, Izmir,. Turkey. The air-dried plant materials were cut into small pieces and ground into fine powder. The water extract of plant material was prepared as a 2. %w/v infusion and then filtered using Whatman filter paper no. 1 paper. The filtrate was.

  2. In vivo Antimalarial Activity of Methanol and Water Extracts of ...

    African Journals Online (AJOL)

    1Vocational School of Health Services, Celal Bayar University, Manisa, 2Department of Pharmacognosy, Faculty of Pharmacy,. Ege University ... potential of this plant. Preliminary phytochemical analysis and acute toxicity studies of the water and methanol extracts prepared from Eryngium thorifolium were also conducted.

  3. Un'occasione per capire cos'è il Grid

    CERN Multimedia

    2006-01-01

    After the WWW, the giant computing infrastructure Grid was also created at CERN in Geneva; and to understand the Grid, the Egee (Enabling Grids for e-Science), financed by the European Commission and Cern, a fourth event of Grid Industry Day was organized in Catania

  4. Social and Emotional Outcomes of Child Sexual Abuse: A Clinical Sample in Turkey

    Science.gov (United States)

    Ozbaran, Burcu; Erermis, Serpil; Bukusoglu, Nagehan; Bildik, Tezan; Tamar, Muge; Ercan, Eyyup Sabri; Aydin, Cahide; Cetin, Saniye Korkmaz

    2009-01-01

    Childhood sexual abuse is a traumatic life event that may cause psychiatric disorders such as posttraumatic stress disorder and depression. During 2003-2004, 20 sexually abused children were referred to the Child and Adolescent Psychiatry Clinic of Ege University in Izmir, Turkey. Two years later, the psychological adjustment of these children (M…

  5. Comparative Coh-Metrix Analysis of Reading Comprehension Texts: Unified (Russian) State Exam in English vs. Cambridge First Certificate in English

    Science.gov (United States)

    Solnyshkina, Marina I.; Harkova, Elena V.; Kiselnikov, Aleksander S.

    2014-01-01

    The article summarizes the results of the comparative study of Reading comprehension texts used in B2 level tests: Unified (Russia) State Exam in English (EGE) and Cambridge First Certificate in English (FCE). The research conducted was mainly focused on six parameters measured with the Coh-Metrix, a computational tool producing indices of the…

  6. The Meaning of Marriage According to University Students: A Phenomenological Study

    Science.gov (United States)

    Koçyigit Özyigit, Melike

    2017-01-01

    The aim of this study is to reveal the meanings university students attribute to marriage. The sample of the study consists of 14 final year students (7 males and 7 females), whose ages range between 22 and 32, studying in the Education Faculty at Ege University. The study is of "phenomenological research design". "Semi-structured…

  7. Einstein Gravity Explorer–a medium-class fundamental physics mission

    NARCIS (Netherlands)

    Schiller, S.; Tino, G.M.; Gill, E.

    2008-01-01

    The Einstein Gravity Explorer mission (EGE) is devoted to a precise measurement of the properties of space-time using atomic clocks. It tests one of the most fundamental predictions of Einstein’s Theory of General Relativity, the gravitational redshift, and thereby searches for hints of quantum

  8. Egens sundhedsproblemer på grundvandsnære jorde

    DEFF Research Database (Denmark)

    Callesen, Ingeborg; Jørgensen, Bruno Bilde; Fischer, Lene

    2017-01-01

    alvorlige patogene arter kan alligevel ikke udelukkes, da patogene bakterier er fundet på skrantende ege i England. Honningsvamp (Armillaria sp.) og den hjemmehørende art stor egepragtbille (A. sulcicollis) var almindeligt forekommende på døde og døende træer, men anses som sekundære. Det blev vist, at der...

  9. genetic parameters for body weights of quail using random ...

    African Journals Online (AJOL)

    CMT

    Mail: yavuz@ziraat.ege.edu.tr. Introduction. Genetic evaluation of animals has been based on several traits depending on the species such as milk characteristics, body weight, feed intake and longevity. A trait that changes with age as a trajectory ...

  10. Effect of Bamboo ( Bambusa valgaris ) and Elephant grass ...

    African Journals Online (AJOL)

    Antioxidant potential of bamboo and elephant grass leaf extracts were evaluated in cooked and raw broiler meat stored under refrigeration at 3±20C. To a separate 350g of minced broiler meat, 1.5% bamboo leaf extract (BLE) or elephant grass extract (EGE) was added. There was a negative control without additive while a ...

  11. L'Europa accelera sul progetto Grid

    CERN Multimedia

    2003-01-01

    "Il consorzio pan-europeo Egee sta pilotando a Bruxelles la complessa operazione che dotera' l'Europa di un mercato comune delle risorse di calcolo sulla base del modello Grid (griglia di calcolo, trasporto e distribuzione di dati)" (1 page).

  12. The effect of sulphur applications on nutrient composition, yield and ...

    African Journals Online (AJOL)

    STORAGESEVER

    2008-09-17

    Sep 17, 2008 ... 2Ege University, Faculty of Agriculture, Department of Field Crops, 35100, Bornova, Izmir, Turkey. Accepted 21 August ... The trial was conducted in a randomized complete block design with three replications. The results ... common and so sulphur fertilizing in cereal agriculture has very important role in ...

  13. The Elon Gap Experience: A Transformative First-Year Experience

    Science.gov (United States)

    Morrison, Stephen T.; Burr, Katherine H.; Waters, Rexford A.; Hall, Eric E.

    2016-01-01

    The Elon Gap Experience (EGE) was conceived out of Elon University's most recent strategic plan, the Elon Commitment (Elon University, 2009). One theme calls for "strategic and innovative pathways in undergraduate and graduate education," specifically "to launch a service program as part of a gap-year program" (Elon University,…

  14. Macrofauna Associated with the Sponge Neopetrosia exigua ...

    African Journals Online (AJOL)

    Centre, Quatre Bornes, Mauritius; 4Centro de Oceanografia, Faculdade de Ciências,. Universidade de Lisboa, Campo Grande, 1749-016 Lisboa, Portugal; 5Department of. Hydrobiology, Faculty of Fisheries, Ege University, Izmir, Turkey; 6Centre of Advance Study in Marine Biology, Annamalai University, Parangipettai-608 ...

  15. RESEARCH ARTICLE Ubiquitous distribution of fluorescent protein ...

    Indian Academy of Sciences (India)

    Navya

    Tasmania, and Lord Howe Island. A. mossambica is distributed in tropical coastal regions of. Southeast Africa, such as south Kenya, Cape Agulhas, and Madagascar. The A. bicolor species is divided into two subspecies, A. bicolor b. and A. bicolor p. (Ege 1939). The distribution is completely different between the two ...

  16. WAJM 28(3) for printing.pmd

    African Journals Online (AJOL)

    dese

    Abbreviations: CCT, Central Corneal Thickness; CDR, Cup Disc Ratio; CS, Contrast Sensitivity; CSLO, Co-focal Scanning Laser Ophthalmoscopy; DCT, Dynamic. Contour Tonometer; EGE, Early Glaucoma Eyes; FACT, ..... Assessment of the symmetry, thickness and colour of the neuroretinal rim is more important.

  17. Research Paper ISSN 0189-6016©2009

    African Journals Online (AJOL)

    Key words: Elaeis guineensis, endothelium, eNOS, coronary artery. Abbreviations: EGE, Elaeis guineensis extract; NO, nitric oxide; eNOS, endothelial NO synthase; EDHF, endothelium-derived hyperpolarizing factor. Abstract. This study was undertaken to investigate the vasodilatory effect of an aqueous extract of Elaeis.

  18. Green synthesis of silver nanoparticles using Arbutus andrachne ...

    African Journals Online (AJOL)

    Methods: The synthesized AgNPs were characterized using the following techniques: ultraviolet-visible ... Plant material. A. andrachne (Ericaceae) was collected from. Cicekliköy (Izmir) during January 2012. The leaves of the plant were identified at Ege. University Faculty ... Powder sample (AgNP) was used, and the X-ray.

  19. AFJU OFC 18(4).indd

    African Journals Online (AJOL)

    imac-1

    20% and periureteral edema in 24%, compared with 47% and. 59%, respectively, reported by Ege et al. [16]. Renal enlarge- ment was detected in 40% of our cases, compared with 36–71% in other reports [15,16,19]. Such differences are related to the degree of calcular obstruction and the presence of secondary infection.

  20. Sea Surface Variability in the Aegean Sea.

    Directory of Open Access Journals (Sweden)

    Şeniz Uçkaç

    2015-12-01

    Full Text Available Ege Denizi’nde yüzey suyu değişimleri. Ege Denizi’nde fiziksel parametreler iklimsel değişimler, tatlısu girdileri ve su döngüsü gibi faktörlere bağlı olarak yer ve zamana göre değişim göstermektedir. Farklı su kütleleri, özellikle Çanakkale boğazından gelen soğuk Karadeniz suyu ve güney kısımdan girmekte olan Levanten suyu Ege Denizi su özelliklerinin karmaşık yapısına katkıda bulunmaktadır. Bu çalışmada Ege Denizi yüzey suyu sirkülasyonu ve fiziksel özelliklerinin değişimi yerinde ölçümler kullanılarak 1986-1994 periyodunda incelenmiştir. Yüzey verisi analizleri yüksek tuzluluk ve yoğunluk değerlerinin ilk olarak Kuzey Ege’de oluştuğunu göstermektedir

  1. From testbed to reality grid computing steps up a gear

    CERN Multimedia

    2004-01-01

    "UK plans for Grid computing changed gear this week. The pioneering European DataGrid (EDG) project came to a successful conclusion at the end of March, and on 1 April a new project, known as Enabling Grids for E-Science in Europe (EGEE), begins" (1 page)

  2. Less toxic method for producing giant paper organ sections for pathology and anatomy education

    Directory of Open Access Journals (Sweden)

    DeMartinis NC

    2014-11-01

    Full Text Available Nicole C DeMartinis, Walter E Finkbeiner Department of Pathology, University of California, San Francisco, San Francisco, CA, USA Purpose: Traditionally, medical school pathology educators have used formalin-fixed specimens to demonstrate effects of diseases on target organs, despite the handling of these "wet" tissues having distinct disadvantages, such as the need for gloves, protective clothing, and appropriate facilities to limit potential fixative moisture and fumes. Paper-mounted sections of solid organs have significant potential as an aid for teaching gross pathology and eliminate the disadvantages of handling formalin-fixed specimens. However, published techniques for preparing giant organ sections include the use of the highly toxic ethylene glycol monoethyl ether (EGEE; 2-ethoxyethanol. We investigated whether replacing EGEE with a less toxic dehydrating and clearing agent, Histo-Clear™, would allow production of high-quality sections.Materials and methods: Whimster's procedure for preparing rapid paper sections of lungs and other organs was modified to incorporate the xylene substitute Histo-Clear in place of EGEE.Results: Giant paper sections of various organs were prepared. In addition to lungs, excellent pathology teaching specimens were prepared from other organs, including the brain, heart, kidney, liver, and colon. Side-by-side comparisons of paper-mounted organ sections prepared using EGEE and Histo-Clear were indistinguishable. The sections prepared using Histo-Clear showed fine anatomical and pathological details.Conclusion: The Gough–Wentworth technique of preparing rapid giant paper sections of organs was made less toxic without sacrificing quality by using Histo-Clear as an alternative to EGEE. Paper-mounted sections offer a safe and portable way for studying macroscopic pathology, and have great potential for use in the anatomy and pathology classroom, as well as in postgraduate pathology training.Keywords: organ

  3. Effects of ethylene glycol ethers on diesel fuel properties and emissions in a diesel engine

    Energy Technology Data Exchange (ETDEWEB)

    Gomez-Cuenca, F.; Gomez-Marin, M. [Compania Logistica de Hidrocarburos (CLH), Central Laboratory, Mendez Alvaro 44, 28045 Madrid (Spain); Folgueras-Diaz, M.B., E-mail: belenfd@uniovi.es [Department of Energy, University of Oviedo, Independencia 13, 33004 Oviedo (Spain)

    2011-08-15

    Highlights: {yields} Effect of ethylene glycol ethers on diesel fuel properties. {yields} Effect of ethylene glycol ethers on diesel engine specific consumption and emissions. {yields} Blends with {<=}4 wt.% of oxygen do not change substantially diesel fuel quality. {yields} Blends with 1 and 2.5 wt.% of oxygen reduce CO and HC emissions, but not smoke. - Abstract: The effect of ethylene glycol ethers on both the diesel fuel characteristics and the exhaust emissions (CO, NO{sub x}, smoke and hydrocarbons) from a diesel engine was studied. The ethers used were monoethylene glycol ethyl ether (EGEE), monoethylene glycol butyl ether (EGBE), diethylene glycol ethyl ether (DEGEE). The above effect was studied in two forms: first by determining the modification of base diesel fuel properties by using blends with oxygen concentration around 4 wt.%, and second by determining the emission reductions for blends with low oxygen content (1 wt.%) and with 2.5 wt.% of oxygen content. The addition of DEGEE enhances base diesel fuel cetane number, but EGEE and EGBE decrease it. For concentrations of {>=}4 wt.% of oxygen, EGEE and diesel fuel can show immiscibility problems at low temperatures ({<=}0 {sup o}C). Also, every oxygenated compound, according to its boiling point, modifies the distillation curve at low temperatures and the distillate percentage increases. These compounds have a positive effect on diesel fuel lubricity, and slightly decrease its viscosity. Blends with 1 and 2.5 wt.% oxygen concentrations were used in order to determine their influence on emissions at both full and medium loads and different engine speeds. Generally, all compounds help to reduce CO, and hydrocarbon emissions, but not smoke. The best results were obtained for blends with 2.5 wt.% of oxygen. At this concentration, the additive efficiency in decreasing order was EGEE > DEGEE > EGBE for CO emissions and DGEE > EGEE > EGBE for hydrocarbon emissions. For NO{sub x}, both its behaviour and the

  4. Kwf-Grid workflow management system for Earth science applications

    Science.gov (United States)

    Tran, V.; Hluchy, L.

    2009-04-01

    In this paper, we present workflow management tool for Earth science applications in EGEE. The workflow management tool was originally developed within K-wf Grid project for GT4 middleware and has many advanced features like semi-automatic workflow composition, user-friendly GUI for managing workflows, knowledge management. In EGEE, we are porting the workflow management tool to gLite middleware for Earth science applications K-wf Grid workflow management system was developed within "Knowledge-based Workflow System for Grid Applications" under the 6th Framework Programme. The workflow mangement system intended to - semi-automatically compose a workflow of Grid services, - execute the composed workflow application in a Grid computing environment, - monitor the performance of the Grid infrastructure and the Grid applications, - analyze the resulting monitoring information, - capture the knowledge that is contained in the information by means of intelligent agents, - and finally to reuse the joined knowledge gathered from all participating users in a collaborative way in order to efficiently construct workflows for new Grid applications. Kwf Grid workflow engines can support different types of jobs (e.g. GRAM job, web services) in a workflow. New class of gLite job has been added to the system, allows system to manage and execute gLite jobs in EGEE infrastructure. The GUI has been adapted to the requirements of EGEE users, new credential management servlet is added to portal. Porting K-wf Grid workflow management system to gLite would allow EGEE users to use the system and benefit from its avanced features. The system is primarly tested and evaluated with applications from ES clusters.

  5. Relationship between Liquidity and Price Bubble in Tehran's Asset Market

    Directory of Open Access Journals (Sweden)

    J. Khodaparast SHIRAZI

    2012-12-01

    Full Text Available In this paper, according to Austrian school, the existence of bubbles in asset market of Tehran from 1998 to 2009 is attributed to the unexpected fluctuations of liquidity. To find out the process of bubble, the state space form and Kalman filter are used and bubble is brought out as unobserved variable of price series. In order to determine the long run relationship between liquidity and price bubble the VAR method proposed by Johanson and Jelisus is used. The result confirms that variation of liquidity has a significant effect on the creating of bubble in long run.

  6. Aplasia cutis congenita with two completely different presentations

    Directory of Open Access Journals (Sweden)

    Sanchaita Bala

    2014-01-01

    Full Text Available Aplasia cutis congenita is a rare disorder, which presents with congenital absence of skin. Besides isolated presentation, it may manifest with other developmental malformation of cardiovascular, gastrointestinal, genitourinary and central nervous systems, and malformation syndromes such as chromosomal abnormalities, Adams-Oliver syndrome, Bart′s syndrome, and Johanson-Bilzzard syndrome. Here, we present two cases of aplasia cutis congenita, which represent two different types of the disease. The first case presented as non-syndromic aplasia cutis congenita of scalp, and the other case presented as a part of Bart′s syndrome.

  7. Knowledge Creation in International Joint Ventures in Emerging Economies

    DEFF Research Database (Denmark)

    Nielsen, Ulrik B.

    demonstrated that creation of new IJV-specific knowledge can be imperative to performance while Pak, Ra, and Lee (2015) demonstrated that IJV parents can become beneficiaries of collaborative sensing and seize the market opportunities (Johanson & Vahlne, 2006). However, inter-organizational knowledge creation...... processes in IJVs have rarely been examined (Pak et al., 2015) especially not in the context of IJVs in emerging economies. This paucity of studies concerning knowledge creation and inter-organizational learning in IJVs have been noted at a critical research gap in the literature (J.-Y. Park, Ha, & Lew...

  8. Addressing service delivery in rural areas through deployment of information and communication technology platforms

    CSIR Research Space (South Africa)

    Foko, Thato E

    2017-05-01

    Full Text Available , laptop or smartphone (Walton & Johanson, 2012). Importantly, at the heart of any well functioning ICT Platforms are the champions. 2.1. The ICT Platform champions The Theory of Change of the project illustrated a need for the Platform champions... is at the heart of this paper. This study attempted to understand the reasons for people accepting and utilising the ICT Platform. The Technology Acceptance Model (TAM) attempts to focus on how people can adopt and utilise a particular technology introduced...

  9. Festivalitiine september / Raivo Kelomees

    Index Scriptorium Estoniae

    Kelomees, Raivo, 1960-

    1999-01-01

    Võrreldakse sept.-s 1999 toimunud 'Ars Electronica' 20. festivali 'Life-Science' Linzis ning 4. Spliti uue filmi ja video festivali Horvaatias. Peapreemiad Linzis: netikategooria - L. Torvals, interaktiivne kunst - L. Hershmann, arvutianimatsioon - C. Wedge. Spliti festivalil esinesid Eestist T. Johanson, M. Rand, J. Kilmi, R. Kelomees. R. Kelomehe CD-ROM "tokyocity.ee" eksponeerus 'Ars Electronica' mediateegis, hiljem Splitis. Järgneb Sirp, 1999, 19. nov., lk. 8. Ilmunud ka kogumikus "Ekraan kui membraan". Tartu, 2007, lk. 76-80 pealkirja all "Festivalirikas september"

  10. Ado Johansoni taluehituse ja kohakujunduse õpetus / Aimur Joandi

    Index Scriptorium Estoniae

    Joandi, Aimur, 1948-2014

    2011-01-01

    19. saj. teisel poolel ei suutnud rehielamu täita uuema aja nõudeid. 20. saj. algul osutus üheks aktiivsemaks taluehituse arendajaks esimene kutseline põllumajandusinstruktor Ado Johanson. Ta tutvus Soome-Rootsi tuntud insener-arhitekti Alfred Sjöströmi põhimõtetega taluehitiste planeerimisel, ruumide ehitamisel, õue-aia valikul, osales taluelamu ehitusjooniste võistlusel, käis välismaal tutvumas eeskujulike taludega ning rakendas siis kuuldut-nähtut Eestis

  11. One-stage and two-stage penile buccal mucosa urethroplasty

    Directory of Open Access Journals (Sweden)

    G. Barbagli

    2016-03-01

    Full Text Available The paper provides the reader with the detailed description of current techniques of one-stage and two-stage penile buccal mucosa urethroplasty. The paper provides the reader with the preoperative patient evaluation paying attention to the use of diagnostic tools. The one-stage penile urethroplasty using buccal mucosa graft with the application of glue is preliminary showed and discussed. Two-stage penile urethroplasty is then reported. A detailed description of first-stage urethroplasty according Johanson technique is reported. A second-stage urethroplasty using buccal mucosa graft and glue is presented. Finally postoperative course and follow-up are addressed.

  12. Fungos zoospóricos (Mastigomycotina) da mata atlântica da Reserva Biológica do Alto da Serra de Paranapiacaba, município de Santo André, SP

    OpenAIRE

    Schoenlein-Crusius, Iracema Helena; Milanez, Adauto Ivo

    1998-01-01

    Trezentas e dezesseis ocorrências de 20 táxons de Mastigomycotina (fungos zoospóricos) foram registradas em folhas de Alchornea triplinervia (Spreng.) Müll. Arg. colocadas em ambientes terrestre e aquático, em amostras de solo e de água de riacho coletadas mensalmente de julho de 1988 a maio de 1990. Entre os 13 táxons de Chytridiomycetes e sete de Oomycetes, as espécies com maior ocorrência foram: Karlingia rosea (De Bary & Woronin) Johanson (35 ocorrências), Polychytrium aggregatum Ajello (...

  13. Kuidas olla peresõbralik tööandja : muret valmistab erisoodustusmaks, kuid hoolivus on ülesanne number üks

    Index Scriptorium Estoniae

    2008-01-01

    Oma ettevõtte peresõbralikkusest ja paindlikkusest räägivad Kädi Vestberg HR factory OÜ-st, Kadri Johanson CV-Keskusest, Kati Oja reisibüroost Estravel, Helena Erm Scania Eesti AS-ist, Moonika Kähr kinnisvarafirmast Uus Maa, Liina Oks Sampo pangast, Reet Treial Balti Investeeringute Grupi Pank AS-ist, Ülle Matt elektroonikafirmast Elcoteq, Silvia Savik Nukuteatrist, Ülle Filin Tele2 Eesti AS-ist, Sirje Tammiste Sirje Tammiste Konsultandibüroost, Getri Järvsoo Fortum Termest AS-ist ja Kärt Kirso AS-ist Kalev Chocolate Factory

  14. Emprego da submucosa intestinal suína em uretroplastias complexas

    Directory of Open Access Journals (Sweden)

    Paulo César Rodrigues Palma

    Full Text Available We report the use of Porcine Intestinal Submucosa (PIS in association with Johanson technique for urethroplasty, in the treatment of recurring urethral stenosis. The patient had obliterans xerotica balanitis and had previously undergone 15 internal uretotomies as well as various unsuccessful urethral dilations. As a result of stenotic extension, another surgery was planned using Johanson technique. During the first part of the surgery, intense local fibrosis was observed, which required greater care and protection to avoid fistulae formation. PIS was interposed to reduce the chances of the occurrence of this dreaded complication. During the second part of the surgery, a skin flap obtained from tissue parallel to the urethral plateau was used to prepare a neourethra according to the norms of this technique. PIS was fixed at its extremities, and interposed between the neourethral suture and the skin suture to prevent any contact between them. The procedure was completed with the use of meatoplasty and glandulaplasty. After 6-month follow up, clinical and urodynamic improvement could be seen. If these results can be confirmed by more extensive studies, PIS will provide new perspectives for complex urethroplasties.

  15. Increased Productivity for Emerging Grid Applications the Application Support System

    CERN Document Server

    Maier, Andrew; Mendez Lorenzo, Patricia; Moscicki, Jakub; Lamanna, Massimo; Muraru, Adrian

    2008-01-01

    Recently a growing number of various applications have been quickly and successfully enabled on the Grid by the CERN Grid application support team. This allowed the applications to achieve and publish large-scale results in a short time which otherwise would not be possible. We present the general infrastructure, support procedures and tools that have been developed. We discuss the general patterns observed in supporting new applications and porting them to the EGEE environment. The CERN Grid application support team has been working with the following real-life applications: medical and particle physics simulation (Geant4, Garfield), satellite imaging and geographic information for humanitarian relief operations (UNOSAT), telecommunications (ITU), theoretical physics (Lattice QCD, Feynman-loop evaluation), Bio-informatics (Avian Flu Data Challenge), commercial imaging processing and classification (Imense Ltd.) and physics experiments (ATLAS, LHCb, HARP). Using the EGEE Grid we created a standard infrastruct...

  16. Strategies for experiment-specific monitoring in the Grid

    CERN Document Server

    Mendez Lorenzo, Patricia; Campana, Simone; Santinelli, Roberto; Lanciotti, Elisa; Miccio, Enzo; Magini, Nicolo; Di Girolamo, Alessandro

    2008-01-01

    This contribution describes how the LHC experiments implement their own Grid resource monitoring, either by internally developed tools, or by reusing tools used for Grid operations, like the Service Availability Monitor (SAM) used for the EGEE operations. The LHC experiments perform most, if not all, of their computing activities on Grid resources. This requires an accurate and updated picture of the status of the Grid services used by them, and of the services which are specific to the experiment. To achieve this, a common method is to periodically execute tests on the services, where the functionalities tested may be different from a VO to another. The SAM framework, developed for the EGEE operations, can be easily used to run and publish the results of arbitrary tests, from basic functionality tests, to high-level operations from real production activities. This contribution describes in detail how the monitoring system of each LHC experiment has taken advantage of SAM. The work covered by this contributio...

  17. Serum pharmacokinetics of choline, trimethylamine, and trimethylamine-N-oxide after oral gavage of phosphatidylcholines with different fatty acid compositions in mice.

    Science.gov (United States)

    Gao, Xiang; Jiang, Chengzi; Xu, Jie; Yanagita, Teruyoshi; Xue, Changhu; Wang, Yuming

    2016-07-13

    Little is known about the pharmacokinetics of phosphatidylcholine (PC)-derived choline, trimethylamine (TMA), and trimethylamine-N-oxide (TMAO). We therefore aim to investigate serum choline, TMA, and TMAO pharmacokinetics following different PCs gavage and compare the difference between PC emulsions and liposomes (SOL). Serum choline, TMA, and TMAO levels were measured after orally gavaged egg yolk PC emulsion (EGE), squid PC emulsion (SQE), soybean PC emulsion (SOE), and SOL in fasted mice. Time to reach peak concentration (Tmax) and productions for TMA and TMAO were more slow and less in SQE group compared with EGE and SOE groups. Tmax for choline, TMA, and TMAO prolonged, and the productions of them were significantly declined in SOL group compared to SOE group. These findings indicated that marine source squid PC could counter-regulate the potential risks of TMAO generation, and the use of liposome as the form of PC supplementary may eliminate TMAO production.

  18. Distributed computing for global health

    CERN Document Server

    CERN. Geneva; Schwede, Torsten; Moore, Celia; Smith, Thomas E; Williams, Brian; Grey, François

    2005-01-01

    Distributed computing harnesses the power of thousands of computers within organisations or over the Internet. In order to tackle global health problems, several groups of researchers have begun to use this approach to exceed by far the computing power of a single lab. This event illustrates how companies, research institutes and the general public are contributing their computing power to these efforts, and what impact this may have on a range of world health issues. Grids for neglected diseases Vincent Breton, CNRS/EGEE This talk introduces the topic of distributed computing, explaining the similarities and differences between Grid computing, volunteer computing and supercomputing, and outlines the potential of Grid computing for tackling neglected diseases where there is little economic incentive for private R&D efforts. Recent results on malaria drug design using the Grid infrastructure of the EU-funded EGEE project, which is coordinated by CERN and involves 70 partners in Europe, the US and Russi...

  19. Academic Dishonesty Tendencies and Values of Teacher Candidates

    OpenAIRE

    Ayşegül KADI; Osman Ferda BEYTEKİN; Hasan ARSLAN

    2016-01-01

    The purpose of this study was to examine the values and academic dishonesty tendencies of teacher candidates. The population of this study included teacher candidates who received pedagogic formation education during 2013-2014 academic semester at the Faculty of Education at Ege University. The study was conducted with 244 teacher candidates, who were chosen through convenient sampling method. Academic Dishonesty Tendency Scale and Portrait Values Questionnaire were used to collect data. It w...

  20. PELVİK OPERASYONLARDA MESANE VE ÜRETER YARALANMALARI

    OpenAIRE

    YILMAZ, Hüseyin; HACIVELİOĞLU, Servet; DİNÇER, Ömer

    2002-01-01

    The genitourinary tract may be injured by a wide variety of blunt and penetrating travma in lovver abdominal operations.We have investigated the localization, the frequency and the complications, of these tatrogenic injuries. In our study, we detected 7 patients hospitalized at Ege University Medical Faculty, Obstetrics and Gynecology Department for urinary tract injury betvveen January 1997- January 2002. These patients were examined retrospectively. We have found the freguencies of urin...

  1. Participants of the "Grid: the Key to Scientific Collaboration", an outstanding UNESCO-ROSTE and CERN event sponsored by Hewlett Packard held on 28 and 29 September at CERN, Geneva.

    CERN Document Server

    Maximilien Brice

    2005-01-01

    Based on the collaboration-fostering and research-enabling role of the grid, CERN and UNESCO are taking the opportunity to invite current and future grid participants, universities and research institutions to a grid event hosted by CERN in Geneva. Through presentations by key grid protagonists from CERN, the European Commission, the EGEE Grid, and the European research community, participants have been able to learn about the capabilities of the grid, opportunities to leverage their research work, and participation in international projects.

  2. CIC portal: a Collaborative and Scalable Integration Platform for High Availability Grid Operations

    OpenAIRE

    Cavalli, Alessandro; Cordier, Hélène; L'Orphelin, Cyril; Reynaud, Sylvain; Mathieu, Gilles; Pagano, Alfredo; Aidel, Osman

    2016-01-01

    International audience; EGEE, along with its sister project LCG, manages the world's largest Grid production infrastructure which is spreading nowadays over 260 sites in more than 40 countries. Just as building such a system requires novel approaches; its management also requires innovation. From an operational point of view, the first challenge we face is to provide scalable procedures and tools able to monitor the ever expanding infrastructure and the constant evolution of the needs. The se...

  3. THE HANDBOOK OF BLENDED LEARNING:Global Perspectives, Local Designs

    OpenAIRE

    ATES, Reviewed By Alev

    2009-01-01

    THE HANDBOOK OF BLENDED LEARNING:Global Perspectives, Local Designs Curtis J. Bonk (ed.) and Charles R. Graham (ed.), Jay Cross (Foreword),Micheal G. Moore Foreword) ISBN: 978-0-7879-7758-0 Publisher: John Wiley & Sons, Inc. Pfeiffer Pages: 624 March 2006.Reviewed by Alev ATESPhD Student at Curriculum and Instruction,Lecturer at Computer Education and Instructional Technologies,Faculty of Education, Ege University, Izmir, TURKEYBlended learning or blended e-learning sounds like aconfusing ter...

  4. THE INDICES OF EXAMINATION TEXTS COMPLEXITY

    OpenAIRE

    Solnyshkina Marina Ivanovna; Kiselnikov Aleksandr Sergeevich

    2015-01-01

    The article presents the results of the analysis aimed at quantitative (word length and sentence length) and qualitative (narrativity, syntactic simplicity, word concreteness, referential cohesion and deep cohesion) characteristics used in Flesh Reading Ease and Coh-Metrix to determine complexity/simplicity of FCE and EGE examination texts corresponding to B2 level by Common European Framework of References. The data used in the research include18 examination texts of three language tests ana...

  5. Grid attacks avian flu

    CERN Multimedia

    2006-01-01

    During April, a collaboration of Asian and European laboratories analysed 300,000 possible drug components against the avian flu virus H5N1 using the EGEE Grid infrastructure. Schematic presentation of the avian flu virus.The distribution of the EGEE sites in the world on which the avian flu scan was performed. The goal was to find potential compounds that can inhibit the activities of an enzyme on the surface of the influenza virus, the so-called neuraminidase, subtype N1. Using the Grid to identify the most promising leads for biological tests could speed up the development process for drugs against the influenza virus. Co-ordinated by CERN and funded by the European Commission, the EGEE project (Enabling Grids for E-sciencE) aims to set up a worldwide grid infrastructure for science. The challenge of the in silico drug discovery application is to identify those molecules which can dock on the active sites of the virus in order to inhibit its action. To study the impact of small scale mutations on drug r...

  6. Economic Impact Assessment of Wind Power Integration: A Quasi-Public Goods Property Perspective

    Directory of Open Access Journals (Sweden)

    Huiru Zhao

    2015-08-01

    Full Text Available The integration of wind power into power grid will bring some impacts on the multiple subjects of electric power system. Economic impacts of wind power integration on multiple subjects of China’s electric power system were quantitatively assessed from Quasi-public goods property perspective in this paper. Firstly, the Quasi-public goods property of transmission services provided by power grid corporations was elaborated. Secondly, the multiple subjects of China’s electric power system, which include electricity generation enterprises (EGEs, power grid corporations (PGCs, electricity consumers (ECs, and environment, were detailed analyzed. Thirdly, based on the OPF-based nodal price model and transmission service cost allocation model, the economic impact assessment model of wind power integration was built from Quasi-public goods property perspective. Then, the IEEE-24 bus system employed in this paper was introduced according to current status of China’s electric power system, and the modeling of wind turbine was also introduced. Finally, the simulation analysis was performed, and the economic impacts of wind power integration on EGEs, PGCs, ECs and Environment were calculated. The results indicate, from Quasi-public goods property perspective, the wind power integration will bring positive impacts on EGEs, PGCs and Environment, while negative impacts on ECs. The findings can provide references for power system managers, energy planners, and policy makers.

  7. The Comparison of Effects of Gamma Radiation of Crude Oil Yield on Some Sunflower (Helianthus Annuus Seeds

    Directory of Open Access Journals (Sweden)

    Havser ERTEM VAİZOĞULLAR

    2015-01-01

    Full Text Available This study compares the effects of different doses gamma radiation on crude oil yield and moisture of different six variety sunflower (Helianthus annuus L. seeds. As materials, sunflower variety Ege-2001, Turay, AS-508, Tunca, TR-3080 and Tarsan-1018 seeds were used and irradiated with doses of 0 (control, 100, 200, 300, 400 and 500 Gy gamma radiation. Irradiation was performed in a cesium (Ce137 Gammacell 3000 Elan source, dose rate about 9.75 Gy/min (2900 Ci in the Pamukkale University Faculty of Medicine in the department of the radiological. Moisture amount of seeds were also measured by AOCS standarts. Extraction of the seeds was done with soxhlet apparatus using petroleum ether by hot continuous extraction for 6 hours.  It was found that the highest moisture rate in 100 Gy for all seeds variety. The moisture rate ranged between 3.00 and 9.68% in TR-3080 and Ege-2001, respectively. According to the our results, seed moisture content was affected by gamma radiation in a significant negative one-way. The significant reduction in seed moisture content (9.68% began at 100 Gy of gamma rays and continued to decline to up to 4.04% at 500 Gy. The crude oil yield showed not a important increase in 100 and 200 Gy doses. The result showed that the highest crude oil yield was also obtained from 400 Gy and 33.49% in Ege-2001 seeds.

  8. Shadows behind the computers

    CERN Multimedia

    2007-01-01

    EGEE organized a shadowing day to spur female students to take up careers in the IT field. Eleven female staff from CERN’s IT Department were kept under close surveillance last week, shadowed by female students from the Collège du Léman International School as part of the Enabling Grids for E-sciencE project Gender Action Plan. The shadowing day was aimed at inspiring young women to think of careers in information technology, by passing on the message that careers in science are open to both men and women and can be rewarding and fun. The students were given a tour of the ATLAS physics experiment and the CERN Computer Centre, as well as the opportunity for one-to-one interaction with CERN IT staff. Traditionally, fewer women work in the IT sector; women currently represent 21% of EGEE staff. The shadowing day was held as part of the EGEE Gender Action Plan, reflecting a commitment to reducing this gender gap. Other initiatives in...

  9. EU Commissioner visits CERN

    CERN Multimedia

    2005-01-01

    European Commissioner Viviane Reding in front of one of the computers showing how the Grid works and, from left to right, Robert Aymar, CERN's Director-General, Wolfgang von Rüden, Head of the Information Technology Department, and Bob Jones, the newly appointed director of the EGEE project since 1st November. Viviane Reding, European Commissioner for Information Society and Media, visited CERN on 28 October. Accompanied throughout by CERN's Director-General, Robert Aymar, and the Head of the Information Technology Department, Wolfgang von Rüden, the Commissioner visited the ATLAS cavern before going on to the Information Technology Department, where she was given a complete overview of CERN's activities in the strategic field of Grid computing. Viviane Reding's visit coincided with the end of the EGEE (Enabling Grids for E-sciencE) conference, which took place in Pisa in Italy. Co-ordinated by CERN and funded by the European Commission, the EGEE project aims to set up a worldwide grid infrastructure for sc...

  10. EOSINOPHILIC GASTROENTERITIS

    Directory of Open Access Journals (Sweden)

    Borut Štabuc

    2003-07-01

    Full Text Available Background. Eosinophilic gastroenteritis (EGE is a rare disorder of unknown etiology, characterised by infiltrating eosinophils into one or more layers of gastrointestinal tract and various gastrointestinal manifestations. Signs and symptoms are related to the layer and extent of bowel involved with eosinophilic infiltration bowel with mucosa, muscle, subserosa or all three affected. Steroid therapy remains the corner stone of treatment.Patients and methods. This paper describes a case of 70-yearold male patient with eosinophilic mucosal disease of upper intestinal wall repeatedly admitted because of epigastralgias, nausea, vomiting and losing weight. Because of hypereosinophilia, a biopsy of duodenal mucosa was performed, despite the normal endoscopic appearance. Numerous eosinophilic infiltrates were histologically confirmed in mucosa and submucosa and remission followed metilprednisolon therapy.Results. After two years signs of ilness reapearred, and again metilprednisolon therapy was followed by remission which still last.Conclusions. EGE needs to be recognized by the clinician because it can masquerade as the irritable bowel syndrome. The diagnosis of EGE is confirmed by a characteristic biopsy. Treatment is empiric and gauged to the severity of the clinical manifestations.

  11. Actor Bonds in Situations of Discontinuous Business Activities

    DEFF Research Database (Denmark)

    Skaates, Maria Anne

    2000-01-01

    . Furthermore the governance structure of markets characterized by discontinuous business activities is either that of the "socially constructed market" (Skaates, 2000) or that of the (socially constructed) network (Håkansson and Johanson, 1993). Additionally relationships and actor bonds vary substantially...... in situations of discontinuity. Therefore an analysis and comparison of relevant concepts that capture the key generative features of actor bonds in both socially constructed networks and socially constructed markets is undertaken. These concepts include the "milieu" of project marketing (Cova et al., 1996......) and the institutional concept of the "field". Finally this paper introduces the concept of "social capital" (Bourdieu, 1983) and discusses whether it can be used to conceptualize the dynamic features of actor bonds in situations of discontinuity....

  12. Getting Embedded in Industry Networks Abroad

    DEFF Research Database (Denmark)

    Gretzinger, Susanne; Dyhr Ulrich, Anna Marie; Hollensen, Svend

    with entering such foreign markets remain significant, especially for inexperienced SMEs. These challenges can include inadequate knowledge about a host country’s culture, norms, values and business environment, and a lack of embeddedness in the industry networks abroad. Such barriers can often hinder...... (Hollensen, 2017). This research project aims to explain how the “incubator” can support the acquisition of lacking experiental knowledge and facilitate the process of getting embedded in markets or industrial networks abroad. Theoretical foundation This paper adopts an industrial network approach in line...... with Mats, et al. (2015) and Johannson/Vahlne (2015). On the one hand it is assumed that resources, actors, exchange- and coordination-mechanism are vital determinants influencing the degree of embeddedness of companies in industry networks abroad (Mats, Holm, Johansson 2015, Johanson and Vahlne, 2015...

  13. La Innovación Como Competencia Central En La Internacionalización De Las Firmas Latinoamericanas: El Proceso De Bico Internacional, Empresa Del Grupo Carvajal S.A.1

    Directory of Open Access Journals (Sweden)

    Héctor Ochoa Díaz, Ph.D

    2011-04-01

    Full Text Available Bico Internacional es una empresa colombiana que ha marcado nuevas tendencias en la internacionalización de su operación. Este documento expone un análisis de caso referente a la experiencia de Bico en Colombia y en el extranjero, complementado con la aplicación de modelos teóricos como los de Prahalad y Hamel, Uppsala, Johanson y Vahlne y el propuesto por Stephen H. Rhinesmith, con el objeto de explicar el proceso de expansión de mercados seguido por la compañía. Se concluye que Bico es una empresa con gran capacidad para responder a los desafíos que requieren los entornos locales e internacionales, pero también tiene gran habilidad de innovar en sus productos, en el diseño de su estructura organizativa y en sus estrategias de marketing.

  14. Lähme, naised / Tiina Kuuler

    Index Scriptorium Estoniae

    Kuuler, Tiina, 1969-

    2008-01-01

    Muusikasündmustest: "Laulus on Eestit" 8. aug. Hiiumaal Kärdla laululaval, "Päikeseloojangumuusika: Vägilased" 8. aug. Hiiumaa Kõpu tuletornis, "Kaunid kontserdid Käsmus" (8. aug. Johanson ja vennad, 9. aug. Indigolapsed, 10. aug. Jääboiler), näitemäng "Ernesaks ja Oamats" 16.-17. aug. Raasikul Harju-Jaani kirikumõisas, Leigo järvemuusika (8. aug. ürgsed hümnid, Vaiko Eplik ja Eliit, Jimi Tenor & Kabu Kabu, Eivor ja Tallinna Kammerorkester, Chalice'i uue plaadi esitlus), "Promenaad Kadriorus" 14. aug. (promenaadiorkester Peeter Sauli dirigeerimisel ja solistid), rokkooper "Ruja" 15.-17. ja 19., 21.-24. aug. Vanemuise suvelaval, Birgitta festival 8.-16. aug. Pirita kloostris

  15. A study of the non-isothermal crystallization kinetic of Zn10Se90 glass

    Science.gov (United States)

    Abdel-Rahim, M. A.; Hafiz, M. M.; Abdel-Latief, A. Y.; Abd-Elnaiem, Alaa M.; Alwany, A. Elwhab. B.

    2015-06-01

    The glass transition and the crystallization kinetics of Zn10Se90 glass by differential thermal analysis (DTA) technique under non-isothermal conduction were studied. The effective activation energies of the glass transition and the crystallization have been evaluated on the basses of the Kissinger and Matusita et al. approximations. Kinetic parameters of the crystallization process are significantly influenced by the heating rate. We have compared the experimental DTA with the calculated data curves for Zn10Se90 system using the Johanson-Mehl-Avrami (JMA) and Sestak-Berggren SB( M, N) models. Simulation results indicated that the SB( M, N) model is more suitable for describing the crystallization kinetics for the studied composition. Furthermore, the crystalline phases of annealed Zn10Se90 were characterized by X-ray diffraction. The surface morphology of the annealed samples was examined using scanning electron microscopy.

  16. Eesti Panga ehitised 1918-1940 / Mart Kalm

    Index Scriptorium Estoniae

    Kalm, Mart, 1961-

    2004-01-01

    Sõdadevaheline Eesti ja pangaehitus. Eesti Pank ehitab: Viljandi osakonna hoone (1927, K. Burman, taastati 1956-61 I. Jaaguse projekti järgi), Petseri osakonna hoone (1929-30, F. Adoff), Rakvere osakonna hoone (1933, F. Adoff), Tallinna peapanga hoone arhitektuurivõistlus (1933, I auhind - E. Sacharias, B. Tshernov) ja peapanga hoone (1933-35, F. Adoff, H. Johanson, E. Habermann), Tartu osakonna hoone (1935-36, A. Matteus, K. Burman, aiakujundaja J. Port) ja selle skulptuurkaunistused (J. Raudsepp, A. Eller), Võru osakonna hoone (1937-38, E. Kuusik, A. Soans, reljeefid - A. Kaasik), Pärnu pangahoone arhitektuurivõistlus (1939, parimad A. Kotli ja E. Kuusik-A. Soans) ja Pärnu osakonna hoone (1939-u. 1945, A. Kotli, A. Soans, reljeefid - J. Raudsepp), ametnike elamu Tallinnas Kentmanni 20A (1924-25), Eesti Maakrediitseltsi büroo- ja eluhoone Tallinnas Sakala 4 (1935-36, E. Kuusik)

  17. Sustainable support for WLCG through the EGI distributed infrastructure

    Science.gov (United States)

    Antoni, Torsten; Bozic, Stefan; Reisser, Sabine

    2011-12-01

    Grid computing is now in a transition phase from development in research projects to routine usage in a sustainable infrastructure. This is mirrored in Europe by the transition from the series of EGEE projects to the European Grid Initiative (EGI). EGI aims at establishing a self-sustained grid infrastructure across Europe. The main building blocks of EGI are the national grid initiatives in the participating countries and a central coordinating institution (EGI.eu). The middleware used is provided by consortia outside of EGI. Also the user communities are organized separately from EGI. The transition to a self-sustained grid infrastructure is aided by the EGI-InSPIRE project, aiming at reducing the project-funding needed to run EGI over the course of its four year duration. Providing user support in this framework poses new technical and organisational challenges as it has to cross the boundaries of various projects and infrastructures. The EGI user support infrastructure is built around the Gobal Grid User Support system (GGUS) that was also the basis of user support in EGEE. Utmost care was taken that during the transition from EGEE to EGI support services which are already used in production were not perturbed. A year into the EGI-InSPIRE project, in this paper we would like to present the current status of the user support infrastructure provided by EGI for WLCG, new features that were needed to match the new infrastructure, issues and challenges that occurred during the transition and give an outlook on future plans and developments.

  18. Toxicities of ethylene glycol and ethylene glycol monoethyl ether in Fischer 344/N rats and B6C3F/sub 1/ mice

    Energy Technology Data Exchange (ETDEWEB)

    Melnick, R.L.

    1984-08-01

    The toxicities of ethylene glycol (EG) and ethylene glycol monoethyl ether (EGEE) were studied in Fischer 344/N rats and B6C3F/sub 1/ mice. In a 13-week study, EG was administered in feed to groups of 10 rats and 10 mice of both sexes at dose levels of 0 (control), 0.32, 0.63, 1.25, 2.5, and 5.0%. Kidney/body weight ratios were elevated in the 2.5 and 5.0% dose groups of male and female rats relative to controls, while serum urea nitrogen and serum creatinine levels were elevated in the two highest dose groups of male rats. Toxic nephrosis and crystal deposits in renal tubules were observed in the 2.5 and 5.0% dose groups of male rats. Crystals were also observed in brains of male rats in the 5.0% dose group. Nephrosis was the only lesion observed in female rats (5.0% dose group). Mild, compound-related lesions were seen in kidneys (nephrosis) and livers (centrilobular degeneration) of male mice in the 2.5 and 5.0% dose groups. Groups of 50 rats and 50 mice of both sexes were administered EGEE by gavage in a 2-year study at dose levels of 0 (control), 0.5, 1.0 and 2.0 g/kg body weight. Gross lesions noted at necropsy indicate that chronic treatment of rats with EGEE at dose levels of 0.5 or 1.0 g/kg body weight caused an apparent enlargement of the adrenal gland in male rats and interfered with the development of spontaneous lesions of the spleen (males and females), pituitary (males and females), testis (males), and subcutaneous tissue in the mammary gland region (females) that commonly occur in the aging Fischer 344/N rat. 12 references, 4 figures, 8 tables.

  19. Grid Added Value to Address Malaria

    CERN Document Server

    Breton, V; Hofmann, M

    2008-01-01

    Through this paper, we call for a distributed, internet-based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a non-proprietary peer-production of information-embedding goods. And we propose to use the grid technology to enable such a world wide "open source" like collaboration. The first step towards this vision has been achieved during the summer on the EGEE grid infrastructure where 46 million ligands were docked for a total amount of 80 CPU years in 6 weeks in the quest for new drugs.

  20. Las esofagogastroenteritis eosinofílicas dentro del espectro de las alergias alimentarias

    National Research Council Canada - National Science Library

    Sánchez-Fayos Calabuig, P; Martín Relloso, M.J; Porres Cubero, J.C

    2006-01-01

    ... alimentarias inmunológicas que oscila entre aquellas en que «todo» depende de una IgE específica (anafilaxias alimentarias GI) y aquellas otras en que «nada» depende de esta reagina (esprue celíaco). Una posición intermedia ocuparían las EGE-Eos en las que parecen solaparse reacciones inmunes de carácter celular, junto a un cierto papel de la ...

  1. High liquid fuel yielding biofuel processes and a roadmap for the future transportation

    Science.gov (United States)

    Singh, Navneet R.

    In a fossil-fuel deprived world when crude oil will be scarce and transportation need cannot be met with electricity and transportation liquid fuel must be produced, biomass derived liquid fuels can be a natural replacement. However, the carbon efficiency of the currently known biomass to liquid fuel conversion processes ranges from 35-40%, yielding 90 ethanol gallon equivalents (ege) per ton of biomass. This coupled with the fact that the efficiency at which solar energy is captured by biomass (fast-hydropyrolysis/hydrodeoxygenation is proposed which can achieve liquid fuel yield of 215 ege/ton consuming 0.11 kg hydrogen per liter of oil. Due to the lower hydrogen consumption of the H2Bioil process, synergistically integrated transition pathways are feasible where hot syngas derived from coal gasification (H2Bioil-C) or a natural gas reformer (H 2Bioil-NG) is used to supply the hydrogen and process heat for the biomass fast-hydropyrolysis/hydrodeoxygenation. Another off-shoot of the H2Bioil process is the H2Bioil-B process, where hydrogen required for the hydropyrolysis is obtained from gasification of a fraction of the biomass. H2Bioil-B achieves the highest liquid fuel yield (126-146 ege/ton of biomass) reported in the literature for any self-contained conversion of biomass to biofuel. Finally, an integration of the H2Bioil process with the H2CAR process is suggested which can achieve 100% carbon efficiency (330 ege/ton of biomass) at the expense of 0.24 kg hydrogen/liter of oil. A sun-to-fuel efficiency analysis shows that extracting CO2 from air and converting it to liquid fuel is at least two times more efficient than growing dedicated fuel crops and converting them to liquid fuel even for the highest biomass growth rates feasible by algae. This implies that liquid fuel should preferably be produced from sustainably available waste (SAW) biomass first and if the SAW biomass is unable to meet the demand for liquid fuel, then, CO2 should be extracted from air

  2. Fabrication of One-Dimensional Zigzag [6,6]-PhenylC61-Butyric Acid Methyl Ester Nanoribbons from Two-Dimensional Nanosheets (Open Access: Author’s Final)

    Science.gov (United States)

    2015-09-18

    depends on the growth conditions.14,30,31 Zheng et al.14 performed a detailed study and suggested that the PCBM crystal- lizes in the hexagonal lattice ...the studied super- cell consisted of 48 PCBM molecules (4224 atoms), where the periodic dimension had a lattice parameter of 34.64 Å, while the other...Grant No. 2013-5252). E.G.E. ac- knowledges support from Ångpanneföreningen’s Foundation (14-541). H.R.B. thanks the JC Kempe Foundation for support. The

  3. A whole-plant chamber system for parallel gas exchange measurements of Arabidopsis and other herbaceous species.

    Science.gov (United States)

    Kölling, Katharina; George, Gavin M; Künzli, Roland; Flütsch, Patrick; Zeeman, Samuel C

    2015-01-01

    Photosynthetic assimilation of carbon is a defining feature of the plant kingdom. The fixation of large amounts of carbon dioxide supports the synthesis of carbohydrates, which make up the bulk of plant biomass. Exact measurements of carbon assimilation rates are therefore crucial due to their impact on the plants metabolism, growth and reproductive success. Commercially available single-leaf cuvettes allow the detailed analysis of many photosynthetic parameters, including gas exchange, of a selected leaf area. However, these cuvettes can be difficult to use with small herbaceous plants such as Arabidopsis thaliana or plants having delicate or textured leaves. Furthermore, data from single leaves can be difficult to scale-up for a plant shoot with a complex architecture and tissues in different physiological states. Therefore, we constructed a versatile system-EGES-1-to simultaneously measure gas exchange in the whole shoots of multiple individual plants. Our system was designed to be able record data continuously over several days. The EGES-1 system yielded comparable measurements for eight plants for up to 6 days in stable, physiologically realistic conditions. The chambers seals have negligible permeability to carbon dioxide and the system is designed so as to detect any bulk-flow air leaks. We show that the system can be used to monitor plant responses to changing environmental conditions, such as changes in illumination or stress treatments, and to compare plants with phenotypically severe mutations. By incorporating interchangeable lids, the system could be used to measure photosynthetic gas exchange in several genera such as Arabidopsis, Nicotiana, Pisum, Lotus and Mesembryanthemum. EGES-1 can be introduced into a variety of growth facilities and measure gas exchange in the shoots diverse plant species grown in different growth media. It is ideal for comparing photosynthetic carbon assimilation of wild-type and mutant plants and/or plants undergoing

  4. Editor-in-Chief

    Directory of Open Access Journals (Sweden)

    M Yavuz COŞKUN

    2013-06-01

    Full Text Available Andrejs Geske (University of Latvia, Latvia B. N. Ghosh (Eastern Med. Univ. North Cyprus Bayram Ürekli (University of Selçuk, Türkiye Erdinç Didar (American University, Bulgaria Ercan Tatlıdil (University of Ege, Türkiye Erman Artun (University of Çukurova, Türkiye Hikmet Y. Celkan (University of Gaziantep, Türkiye Hüseyin Bağcı (METU, Türkiye Jean Crombois (American University, Bulgaria Kemal Silay (Indiana University, USA Lelio Iapadre (University of L'Aquila, Italy Michael Goldman (University of Minnesota, USA

  5. The Effect of Cutting On The Yield and Yield Components of Bread Wheat (Triticum aestivum L.) Cultivars

    OpenAIRE

    ÇELEN, A. Esen; SOYA, Hikmet

    1998-01-01

    In the research conducted in the fields of Field Crops Department of Faculty of Agriculture of Ege University, Bornova, İzmir, Turkey in 1993-94 and 1994-95, the effects of cutting treatments [a. uncut control, b. cutting at Zadoks stage 25 (main stem and 5 tillers), c. cutting at Zadoks stage 30 (at the end of tillering, pseudostem erection), and d. cutting at Zadoks stage 31 (first node detectable) ] on the seed yield and some yield components of two bread wheat cultivars (Cumhuriyet-75 and...

  6. Dr Viviane Reding, Commissioner for Information Society and Media, European Commission

    CERN Document Server

    Maximilien Brice

    2005-01-01

    During this visit to CERN, to be briefed on the use of Grids by CERN, Viviane Reding, European Commissioner for Information Society and Media, said "On hearing about EGEE's achievements, I wanted to see for myself some of the practical benefits that this Grid technology is providing. I'm very satisfied to see such a major step forward in collaborative computing between scientists across Europe and even on a global scale. Europe's strategic investments in Grids and in the GEANT network infrastructure are certainly already paying dividends."

  7. Deployment of a Grid-based Medical Imaging Application

    CERN Document Server

    Amendolia, S R; Frate, C; Gálvez, J; Hassan, W; Hauer, T; Manset, D; McClatchey, R; Odeh, M; Rogulin, D; Solomonides, T; Warren, R

    2005-01-01

    The MammoGrid project has deployed its Service-Oriented Architecture (SOA)-based Grid application in a real environment comprising actual participating hospitals. The resultant setup is currently being exploited to conduct rigorous in-house tests in the first phase before handing over the setup to the actual clinicians to get their feedback. This paper elaborates the deployment details and the experiences acquired during this phase of the project. Finally the strategy regarding migration to an upcoming middleware from EGEE project will be described. This paper concludes by highlighting some of the potential areas of future work.

  8. WLCG-specific special features in GGUS

    CERN Document Server

    Antoni, T; Dimou, M; CERN. Geneva. IT Department

    2010-01-01

    The user and operations support of the EGEE series of projects can be captioned "regional support with central coordination". Its central building block is the GGUS portal which acts as an entry point for users and support staff. It is also as an integration platform for the distributed support effort. As WLCG relies heavily on the EGEE infrastructure it is important that the support infrastructure covers the WLCG use cases of the grid. During the last year several special features have been implemented in the GGUS portal to meet the requirements of the LHC experiments needing to contact the WLCG grid infrastructure, especially their Tier 1 and Tier 2 centres. This paper summarises these special features, with particular focus on the alarm and team tickets and the direct ticket routing, in the context of the overall user and operations support infrastructure. Additionally we will present the management processes for the user support activity, detailing the options which the LHC VOs have to participate in this...

  9. Kids Enjoy Grids

    CERN Multimedia

    2007-01-01

    I want to come back and work here when I'm older,' was the spontaneous reaction of one of the children invited to CERN by the Enabling Grids for E-sciencE project for a 'Grids for Kids' day at the end of January. The EGEE project is led by CERN, and the EGEE gender action team organized the day to introduce children to grid technology at an early age. The school group included both boys and girls, aged 9 to 11. All of the presenters were women. 'In general, before this visit, the children thought that scientists always wore white coats and were usually male, with wild Einstein-like hair,' said Jackie Beaver, the class's teacher at the Institut International de Lancy, a school near Geneva. 'They were surprised and pleased to see that women became scientists, and that scientists were quite 'normal'.' The half-day event included presentations about why Grids are needed, a visit of the computer centre, some online games, and plenty of time for questions. In the end, everyone agreed that it was a big success a...

  10. The neural component-process architecture of endogenously generated emotion.

    Science.gov (United States)

    Engen, Haakon G; Kanske, Philipp; Singer, Tania

    2017-02-01

    Despite the ubiquity of endogenous emotions and their role in both resilience and pathology, the processes supporting their generation are largely unknown. We propose a neural component process model of endogenous generation of emotion (EGE) and test it in two functional magnetic resonance imaging (fMRI) experiments (N = 32/293) where participants generated and regulated positive and negative emotions based on internal representations, usin self-chosen generation methods. EGE activated nodes of salience (SN), default mode (DMN) and frontoparietal control (FPCN) networks. Component processes implemented by these networks were established by investigating their functional associations, activation dynamics and integration. SN activation correlated with subjective affect, with midbrain nodes exclusively distinguishing between positive and negative affect intensity, showing dynamics consistent generation of core affect. Dorsomedial DMN, together with ventral anterior insula, formed a pathway supporting multiple generation methods, with activation dynamics suggesting it is involved in the generation of elaborated experiential representations. SN and DMN both coupled to left frontal FPCN which in turn was associated with both subjective affect and representation formation, consistent with FPCN supporting the executive coordination of the generation process. These results provide a foundation for research into endogenous emotion in normal, pathological and optimal function. © The Author (2016). Published by Oxford University Press.

  11. Development of equations for predicting methane emissions from ruminants.

    Science.gov (United States)

    Ramin, M; Huhtanen, P

    2013-04-01

    Ruminants contribute to global warming by releasing methane (CH4) gas by enteric fermentation. This has increased interest among animal scientists to develop and improve equations predicting CH4 production. The objectives of the current study were to collect a data set from respiration studies and to evaluate the effects of dietary and animal factors on CH4 production from diets that can safely be fed to dairy cows, using a mixed model regression analysis. Therefore, diets containing more than 75% concentrate on a dry matter (DM) basis were excluded from the analysis. The final data set included a total of 298 treatment means from 52 published papers with 207 cattle and 91 sheep diets. Dry matter intake per kilogram of body weight (DMIBW), organic matter digestibility estimated at the maintenance level of feeding (OMDm), and dietary concentrations of neutral detergent fiber (NDF), nonfiber carbohydrates (NFC), and ether extract (EE) were the variables of the best-fit equation predicting CH4 energy (CH4-E) as a proportion of gross energy intake (GE): CH4-E/GE (kJ/MJ)=-0.6 (±12.76) - 0.70 (±0.072) × DMIBW (g/kg) + 0.076 (±0.0118) × OMDm (g/kg) - 0.13 (±0.020) × EE (g/kg of DM) + 0.046 (±0.0097) × NDF (g/kg of DM) + 0.044 (±0.0094) × NFC (g/kg of DM), resulting in the lowest root mean square error adjusted for random study effect (adj. RMSE=3.26 kJ/MJ). Total CH4 production (L/d) in the cattle data set was closely related to DM intake. However, further inclusion of other variables improved the model: CH4 (L/d)=-64.0 (±35.0) + 26.0 (±1.02) × DM intake (kg/d) - 0.61 (±0.132) × DMI(2)(centered) + 0.25 (±0.051) × OMDm (g/kg) - 66.4 (±8.22) × EE intake (kg of DM/d) - 45.0 (±23.50) × NFC/(NDF + NFC), with adj. RMSE of 21.1 L/d. Cross-validation of the CH4-E/GE equation [observed CH4-E/GE=0.96 (±0.103) × predicted CH4-E/GE + 2.3 (±7.05); R(2)=0.85, adj. RMSE=3.38 kJ/MJ] indicated that differences in CH4 production between the diets could be predicted

  12. Assessment of Genotoxicity of Ionizing radiation using Tradescantia-Comet assay

    Energy Technology Data Exchange (ETDEWEB)

    Han, Min; Ryu, Tae Ho; Hyun, Kyung Man; Kim, Jin Kyu [Korea Atomic Energy Research Institute, Jeongeup (Korea, Republic of); Wilhelmova, Nad [Institute of Experimental Botany, Prague (Czech Republic)

    2010-05-15

    Over the last two decades, several new methodologies for the detection of DNA damage have been developed. The comet assay is currently used in different areas of biological sciences to detect DNA damage. The comet assay, also called the single cell gel electrophoresis (SCGE) was first introduced by Ostling and Johanson as a microelectrophoretic technique for the direct visualization of DNA damage in individual cells. The comet assay, due to its simplicity, sensitivity and need of a few cells, is ideal as a short-term genotoxicity test. The comet assay can theoretically be applied to every type of eukaryotic cell, including plant cells. Plants are very useful as monitors of genetic effects caused by pollution in the atmosphere, water and soil. Although the genotoxic effects detected by Tradescantia tests cannot be associated with mutagenesis or even carcinogenesis in humans, these bioassays are very useful tools for screening the mutagenic potential in the environment. Experiments were conducted to study the genotoxic effects of ionizing radiations on the genome integrity, particularly of Tradescantia. The increasingly frequent use of Tradescantia as a sensitive environmental bioindicator of genotoxic effects. This study was designed to assess the genotoxicity of ionizing radiation using Tradescnatia-comet assay

  13. Kuu kultuurikulgur

    Index Scriptorium Estoniae

    2008-01-01

    Laivüritusest "Punk 2008" Tartus Athena klubis 11. septembril. Briti ansambel Klaxons 6. okt. Tallinnas klubis Hollywood. Moskva laulja Pelageja 5. okt. Tallinna linnahallis ja 7. okt. Jõhvi kontserdimajas. Heategevuskontserdist 14. sept. Tuhalaane kirikumäel (esinevad Tõnis Mägi, Robert Jürjendal, Ain Agan, Andre Maaker, Riho Sibul, Jaak Johanson, Jaak Tuksam jt). Kultuuritehase toetuseks korraldatud kontserdist "Polyymide päev" (esinesid rokkbändid Sõpruse Puiestee, Malena, Pure Mind ja Pilveke). Ooperi "Hullu mehe aias" lavastusest (lavastaja Robert Annus, koreograafia Triin Reemann, dirigent Veronika Portsmuth, lavakujundus ja kostüümide kunstnik Samal Blak Fääri saartelt) 10.-12. septembrini Tallinnas Kultuurikatlas. Kanada ansambli Simple Plan kontserdist 28. okt. Tallinnas klubis Rock Café. Üritustest Viljandi Pärimusmuusika Aidas: 6. sept. esinevad ansambel Paabel+, akordionist Kulno Malva ja DJ Harlet, etendus "Vaterland" 10. sept., Aida muusikud 11. sept., Anu Taul 13. sept. Fernando Stern ja Ethno in Transit 16. septembril. Gruusia ansambli Shin Egari kontsertidest 9. sept. Tartus Genialistide klubis, 10. sept. Estonia kontserdisaalis, 11. sept. Endla teatri küünis Pärnus, 12. sept. Kultuurivaras Kuressaares

  14. DIFICULDADES ENCONTRADAS NA INTERNACIONALIZAÇÃO DOS NEGÓCIOS PARA O MÉXICO: UM ESTUDO COMPARATIVO ENTRE O RESTAURANTE SPOLETO E A REDE CHINA IN BOX

    Directory of Open Access Journals (Sweden)

    Josir Simeone Gomes

    2010-12-01

    Full Text Available Buscou-se neste estudo de caso, conhecer como o restaurante Spoleto internacionalizou suas operações e quais foram suas principais dificuldades. Em seguida, comparou-se os resultadosdesta pesquisa com uma pesquisa similar publicada por Melo, Andreassi e Oliveira Jr (2010, o qual verificam as experiências da rede China in Box na internacionalização dos negócios. Os resultados da pesquisa apontam que ambas empresas iniciaram suas atividades em mercados internacionais através da parceria com outras empresas e que a escolha do país para expandir os negócios internacionais possuem fundamento na similaridade cultural, possuindo embasamento com as teorias de Martinewski e Gomes (2002 e de Johanson e Vahlne (1977,respectivamente. As dificuldades encontradas na internacionalização são distintas. Enquanto o restaurante Spoleto aponta a dificuldade no controle das operações, a rede China in Box indica a dificuldade em encontrar matéria-prima e ajuste do cardápio para atender os hábitosculturais.

  15. Comet assay: an essential tool in toxicological research.

    Science.gov (United States)

    Glei, M; Schneider, T; Schlörmann, W

    2016-10-01

    The comet assay is a versatile, reliable, cost-efficient, and fast technique for detecting DNA damage and repair in any tissue. It is useable in almost any cell type and applicable to both eukaryotic and prokaryotic organisms. Instead of highlighting one of the numerous specific aspects of the comet assay, the present review aims at giving an overview about the evolution of this widely applicable method from the first description by Ostling and Johanson to the OECD Guideline 489 for the in vivo mammalian comet assay. In addition, methodical aspects and the influence of critical steps of the assay as well as the evaluation of results and improvements of the method are reviewed. Methodical aspects regarding oxidative DNA damage and repair are also addressed. An overview about the most recent works and relevant cutting-edge reviews based on the comet assay with special regard to, e.g., clinical applications, nanoparticles or environmental risk assessment concludes this review. Taken together, the presented overview raises expectations to further decades of successful applications and enhancements of this excellent method.

  16. DNA Damage in Melania Snail (Semisulcospira libertine) Irradiated with Gamma Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Tae Ho; Kim, Jin Kyu [Korea Atomic Energy Research Institute, Advanced Radiation Technology Institute, Jeongeup (Korea, Republic of); An, Kwang Guk [Chungnam National University, Daejeon (Korea, Republic of); Nili, Mohammad [Dawnesh Radiation Research Institute, Barcelona (Spain)

    2010-10-15

    Generally radiological protection has focused on human. But International Commission on Radiological Protection (ICRP) requires the effect data of ionizing radiation on nonhuman biota for the radiological protection of the environment. The choice of a melania snail as a model for environmental biomonitoring of radiation genotoxicity took into account that invertebrates represent one of aquatic species. The comet assay or single cell gel electrophoresis (SCGE) assay, first introduced by Ostling and Johanson, was used to detect DNA single strand breaks and to investigate the application of this technique as a tool for aquatic biomonitoring. Comet assay offers considerable advantages over some other assays used in DNA damage detection, such as chromosomal aberrations, sister chromatid Exchange and the micronucleus test, since there is no need for cells to be in a dividing state. Other advantages are its rapidity, relatively low coast, and wide applicability to virtually any nucleated cell type. In this study, we evaluated DNA damage in cells of Semisulcospira libertina after irradiation with {sup 60}Co gamma radiation by using the comet assay

  17. INTERNATIONALIZATION STRATEGIES OF EMERGING COMPANIES: A COMPARATIVE STUDY OF BRAZILIAN CASES

    Directory of Open Access Journals (Sweden)

    Janaína Maria Bueno

    2012-01-01

    Full Text Available Over the last decade, interest has picked up as to emerging economies and their companies. This recent movement does not imply that previous theories and models are no longer applicable, however, one must analyze, in a broader comprehensive manner, a series of specific context factors and those concerning the management of this kind of company. Therefore, this paper analyzed the internationalization strategies adopted by six Brazilian companies before a set of internationalization models. A qualitative research approach was employed and in-depth interviews were conducted with corporate management level professionals. Companies were divided into three groups according to internationalization times (Group I – over ten years, Group II - between five and ten years, and Group III – under five years. Observations indicated that for Groups I and III companies the product lifecycle (Vernon, 1966 and 1979 and the eclectic paradigm (Dunning, 1980, 1988 and 2000 economic models support justifying internationalization motivations for companies’ internalization whilst the Uppsala model (Johanson and VAHLNE, 1979, 2009, at least in part explains, choice decisions concerning a few countries. As to Group II companies, the product lifecycle model is not the underlying motivation for internationalization, choices being more closely related to sector opportunities and the characteristics of both products and services.

  18. Relationship between Major Developed Equity Markets and Major Frontier Equity Markets of World

    Directory of Open Access Journals (Sweden)

    Muhammad Mansoor Baig

    2016-02-01

    Full Text Available The core aim of this study is to compute the long run relationship between frontier equity markets Pakistan (KSE 100 Index, Argentina (MERVAL BUENOS AIRES stock Exchange, NSE.20 (Kenya, MSM 30 (MSI Oman and equity markets of developed world (OMXS30 Sweden, SMI (Switzerland, SSE Composite Index (China and STI index (Singapore by taking weekly values from stock return prices for the period 1st week of January-2000 to last week of January/2014. Descriptive statistic, Correlation, Augmented dickey fuller (ADF, Phillips Perron test, Johanson and Jelseluis test of co-integration, Granger causality test, Variance Decomposition Test and Impulse Response are used to find the relationship among frontier and developed markets. The results of this study reveal that frontier markets have no long run relationship with equity markets of developed world. Furthermore, this study is helpful for investors to enhance the returns by diversifying the unsystematic risk at given level of profit because results of this study confirm that markets are no cointegrated.

  19. Data Stream Clustering With Affinity Propagation

    KAUST Repository

    Zhang, Xiangliang

    2014-07-09

    Data stream clustering provides insights into the underlying patterns of data flows. This paper focuses on selecting the best representatives from clusters of streaming data. There are two main challenges: how to cluster with the best representatives and how to handle the evolving patterns that are important characteristics of streaming data with dynamic distributions. We employ the Affinity Propagation (AP) algorithm presented in 2007 by Frey and Dueck for the first challenge, as it offers good guarantees of clustering optimality for selecting exemplars. The second challenging problem is solved by change detection. The presented StrAP algorithm combines AP with a statistical change point detection test; the clustering model is rebuilt whenever the test detects a change in the underlying data distribution. Besides the validation on two benchmark data sets, the presented algorithm is validated on a real-world application, monitoring the data flow of jobs submitted to the EGEE grid.

  20. Organising scientific data by dataflow optimisation on the petascale

    CERN Document Server

    Lassnig, Mario

    2008-01-01

    Scientific applications on the Grid are in most cases heavily data-dependent. Therefore, improving scheduling decisions based on the co-allocation of data and jobs becomes a primary issue. Hence, it is crucial to analyse the behaviour of existing data management systems in order to provide accurate information for decision-making middlewares in a scalable way. We show current research issues in understanding the behaviour of data management systems on the petascale to improve Grid performance. We analyse the Distributed Data Management system Don Quijote 2 (DQ2) of the High- Energy Physics experiment ATLAS at CERN. ATLAS presents unprecedented data transfer and data storage requirements on the petascale and DQ2 was built to fulfill these requirements. DQ2 is built upon the EGEE infrastructure, while seamlessly enabling interoperability with the American OSG and the Scandinavian NorduGrid infrastructures. Thus it serves as a relevant production-quality system to analyse aspects of dataflow behaviour in the pet...

  1. DIRAC - The Distributed MC Production and Analysis for LHCb

    CERN Document Server

    Tsaregorodtsev, A

    2004-01-01

    DIRAC is the LHCb distributed computing grid infrastructure for MC production and analysis. Its architecture is based on a set of distributed collaborating services. The service decomposition broadly follows the ARDA project proposal, allowing for the possibility of interchanging the EGEE/ARDA and DIRAC components in the future. Some components developed outside the DIRAC project are already in use as services, for example the File Catalog developed by the AliEn project. An overview of the DIRAC architecture will be given, in particular the recent developments to support user analysis. The main design choices will be presented. One of the main design goals of DIRAC is the simplicity of installation, configuring and operation of various services. This allows all the DIRAC resources to be easily managed by a single Production Manager. The modular design of the DIRAC components allows its functionality to be easily extended to include new computing and storage elements or to handle new tasks. The DIRAC system al...

  2. Wall Street comes to CERN

    CERN Multimedia

    2007-01-01

    CERN will host an event on computing for finance on Wednesday, 21 November, 17:00-19:00, in the Main Auditorium. The event, co-organized by the EGEE project and CERN openlab, brings together four distinguished speakers from the banking industry and IT companies serving financial institutions. The finance sector is one of the driving forces for the use of distributed or Grid computing for business purposes. The speakers will provide insight into how different types of Grid computing – from local clusters to global networks - are being applied in the financial sector. In particular, the event will encourage discussion on how new developments in Grid computing emerging from the world of science can benefit financial institutions. The speakers will be Michael Yoo, Managing Director and Head of the Technical Council at UBS, Fred Gedling, Chief Technology Officer at DataSynapse, Adam Vile, Head of Grid, HPC and Technical Computing at E...

  3. Comparison of the vibroacoustical characteristics of different pianos

    CERN Document Server

    Boutillon, Xavier; Paulello, Stephen

    2012-01-01

    On the basis of a recently proposed vibro-acoustical model of the piano soundboard (X. Boutillon and K. Ege, Vibroacoustics of the piano soundboard: reduced models, mobility synthesis, and acoustical radiation regime. \\emph{submitted to the Journal of Sound and Vibration}, 2011.), we present several models for the coupling between the bridge and the ribbed plate of the soundboard. The models predict the modal density and the characteristic impedance at the bridge as a function of the frequency. Without parameter adjustment, the sub-structure model turns out to fit the experimental data with an excellent precision. The influence of the elastic parameters of wood is discussed. The model predictions are compared for pianos of different sizes and types.

  4. Computer Security: Cryptography and authentication (2/4)

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    Remi Mollon studied computer security at University and he first worked on Grids, with the EGEE project, for a French Bioinformatics institute. Information security being crucial in that field, he developed an encrypted file management system on top of Grid middleware, and he contributed in integrating legacy applications with Grids. Then, he was hired by CERN as a Grid Data Management developer, and he joined the Grid Operational Security Coordination Team. Remi has now moved to CERN Computer Security Team. Remi is involved in the daily security operations, in addition to be responsible to design Team's computer infrastructure, and to participate to several projects, like multi-factor authentication at CERN. With the prevalence of modern information technologies and its increasing integration into our daily live, digital systems become more and more playground for evil people. While in the past, attacks were driven by fame& kudos, nowadays money is the motivating factor. Just the recent months have s...

  5. Adaptively detecting changes in Autonomic Grid Computing

    KAUST Repository

    Zhang, Xiangliang

    2010-10-01

    Detecting the changes is the common issue in many application fields due to the non-stationary distribution of the applicative data, e.g., sensor network signals, web logs and gridrunning logs. Toward Autonomic Grid Computing, adaptively detecting the changes in a grid system can help to alarm the anomalies, clean the noises, and report the new patterns. In this paper, we proposed an approach of self-adaptive change detection based on the Page-Hinkley statistic test. It handles the non-stationary distribution without the assumption of data distribution and the empirical setting of parameters. We validate the approach on the EGEE streaming jobs, and report its better performance on achieving higher accuracy comparing to the other change detection methods. Meanwhile this change detection process could help to discover the device fault which was not claimed in the system logs. © 2010 IEEE.

  6. Perspectives on Medical Students’ Reflections on Ethical Dilemmas during their Clinical Stay. Oral Presentation, COMET Conference in Aalborg, Denmark

    DEFF Research Database (Denmark)

    Gormsen, Lise Kirstine; Søndergaard, Sara; Hoffmann, Tine

    Work-in- progress Roundtable: Title: What ethical problems are out there? – a study of medical students’ reflexive writing about ethical dilemmas in the clinic. Authors: Lise Gormsen, MD, MHH, PhD., Institute of Clinical Medicine, Aarhus University, Denmark Jane Ege Møller, MA, PhD., Center...... dilemmas, which they identify during their clinical stay in hospitals. Summary of work: This study is the first part of a longitudinal qualitative project that will provide an overview concerning what ethical dilemmas students meet and report aduring their clinical stay and how they reflect about it (cf. D...... reflect themselves. Furthermore the material is ‘ negatively biased’ - the students write about the unsolved dilemmas. Conclusion: Reflective texts can be seen as data material that contains valuable knowledge, both concerning modes of reflection AND what types of ethical dilemmas that is a part...

  7. Medical Data Manager an Interface between PACS and the gLite Data Management System

    CERN Document Server

    Montagnat, Johan; Texier, Romain; Nienartowicz, Krzysztof; Baud, Jean-Philippe

    2008-01-01

    The medical imaging community uses the DICOM image format and protocol to store and exchange data. The Medical Data Manager (MDM) is an interface between DICOM compliant systems such as PACS and the EGEE Data Management System. It opens hospital imaging networks to the world scale Grid while protecting sensitive medical data. It can be accessed transparently from any gLite service. It is an important milestone towards adoption of Grid technologies in the medical imaging community. Hospitals continuously produce tremendous amounts of image data that is managed by local PACS (Picture Archiving and Communication Systems). These systems are often limited to a local network access although the community experiences a growing interest for data sharing and remote processing. Indeed, patient data is often spread out different medical data acquisition centers. Furthermore, researchers in the area often need to analyze large populations whose data can be gathered through federations of PACS. Opening PACS to the outer I...

  8. Medical image registration algorithms assesment: Bronze Standard application enactment on grids using the MOTEUR workflow engine.

    Science.gov (United States)

    Glatard, Tristan; Montagnat, Johan; Pennec, Xavier

    2006-01-01

    Medical image registration is pre-processing needed for many medical image analysis procedures. A very large number of registration algorithms are available today, but their performance is often not known and very difficult to assess due to the lack of gold standard. The Bronze Standard algorithm is a very data and compute intensive statistical approach for quantifying registration algorithms accuracy. In this paper, we describe the Bronze Standard application and we discuss the need for grids to tackle such computations on medical image databases. We demonstrate MOTEUR, a service-based workflow engine optimized for dealing with data intensive applications. MOTEUR eases the enactment of the Bronze Standard and similar applications on the EGEE production grid infrastructure. It is a generic workflow engine, based on current standards and freely available, that can be used to instrument legacy application code at low cost.

  9. Arquitectura de almacenamiento masivo de datos en la infraestructura Grid usando el middlewareglite

    Directory of Open Access Journals (Sweden)

    Iván Fernando Gómez Pedraza

    2012-12-01

    Full Text Available Nowadays, the increase in research projects at universities requires high-computing and mass-storage equipment, creating the need for having a supercomputing infrastructure. This work attempts to find a solution to the storage problems that arise in the different research groups at universities. Massive-storage infrastructures, which use a file system compatible with EGEE middleware, are implemented, taking advantage of the storage space left by working nodes. This should offer a very low-price solution. Additionally, a cluster with fundamental Grid services is created and thus integrated to the intercontinental infrastructure of EELA-2, establishing a platform for distributed computing and storage intended for the scientific community at Universidad Industrial de Santander.

  10. Distributed Data Management on the Petascale using Heterogeneous Grid Infrastructures with DQ2

    CERN Document Server

    Branco, M; Salgado, P; Lassnig, M

    2008-01-01

    We describe Don Quijote 2 (DQ2), a new approach to the management of large scientific datasets by a dedicated middleware. This middleware is designed to handle the data organisation and data movement on the petascale for the High-Energy Physics Experiment ATLAS at CERN. DQ2 is able to maintain a well-defined quality of service in a scalable way, guarantees data consistency for the collaboration and bridges the gap between EGEE, OSG and NorduGrid infrastructures to enable true interoperability. DQ2 is specifically designed to support the access and management of large scientific datasets produced by the ATLAS experiment using heterogeneous Grid infrastructures. The DQ2 middleware manages those datasets with global services, local site services and enduser interfaces. The global services, or central catalogues, are responsible for the mapping of individual files onto DQ2 datasets. The local site services are responsible for tracking files available on-site, managing data movement and guaranteeing consistency of...

  11. Processing moldable tasks on the grid: Late job binding with lightweight user-level overlay

    CERN Document Server

    Moscicki, J T; Sloot, P M A; Lamanna, M

    2011-01-01

    Independent observations and everyday user experience indicate that performance and reliability of large grid infrastructures may suffer from large and unpredictable variations. In this paper we study the impact of the job queuing time on processing of moldable tasks which are commonly found in large-scale production grids. We use the mean value and variance of makespan as the quality of service indicators. We develop a general task processing model to provide a quantitative comparison between two models: early and late job binding in a user-level overlay applied to the EGEE Grid infrastructure. We find that the late-binding model effectively defines a transformation of the distribution of makespan according to the Central Limit Theorem. As demonstrated by Monte Carlo simulations using real job traces, this transformation allows to substantially reduce the mean value and variance of makespan. For certain classes of applications task granularity may be adjusted such that a speedup of an order of magnitude or m...

  12. Availability of IT services during the 2009 CERN annual closure

    CERN Multimedia

    IT Department

    2009-01-01

    Most of the services provided by the IT Department - including WLCG (EGEE) production services - will remain available during the CERN annual closure. No interruptions are scheduled but in the event of a failure, the restoration of services cannot be guaranteed. Problems will be dealt with on a best effort basis only. However, for the following services: Network, Databases, Mail, Web, Windows & Terminal Services, Authentication Services, Indico, CDS, Grid (SAM, FTS, VOMS, GridView): experts should be reachable to start investigations within about half a day except on Christmas Eve and Christmas Day (24 and 25 December) and New Year’s Eve and New Year’s Day (31 December and 1 January). Incidents will be documented at http://cern.ch/ssb. The backup service will remain operational, but backups cannot be guaranteed and file restores may not be possible. Castor: damaged tapes will not be processed. Please note that the Helpdesk will be closed but an operator service will ...

  13. Gediz Akarsuyu Havzasının Biyolojik Özellikleri ve Balıkçılık

    OpenAIRE

    Ünlü, Mehmet

    2013-01-01

    ÖZETBatı Anadolu'da 17.500 km2lik bir alan kaplayan Gediz Akarsuyu Havzası; doğuda, İçbatı Anadolu'daki Mura t Dağından başlar ve orta mecralarda beraberinde birçok tali kollan da alarak, batıda Foça'nın güneyinde Ege Denizi'nde son bulur (Şekil 1). Havza içindeki mevcut akarsu, doğal göl ve baraj gölleri zengin biyolojik özelliklere sahiptir. Bu özelliğinden dolayı da önemli bir balık üretim potansiyeline sahiptir. Bu potansiyelin tamamı bugün çeşitli sebeplerden dolayı d...

  14. ETICS the international software engineering service for the grid

    CERN Document Server

    Di Meglio, A; Couvares, P; Ronchieri, E; Takács, E

    2008-01-01

    The ETICS system is a distributed software configuration, build and test system designed to fulfil the needs of improving the quality, reliability and interoperability of distributed software in general and grid software in particular. The ETICS project is a consortium of five partners (CERN, INFN, Engineering Ingegneria Informatica, 4D Soft and the University of Wisconsin-Madison). The ETICS service consists of a build and test job execution system based on the Metronome software and an integrated set of web services and software engineering tools to design, maintain and control build and test scenarios. The ETICS system allows taking into account complex dependencies among applications and middleware components and provides a rich environment to perform static and dynamic analysis of the software and execute deployment, system and interoperability tests. This paper gives an overview of the system architecture and functionality set and then describes how the EC-funded EGEE, DILIGENT and OMII-Europe projects ...

  15. Grid-based International Network for Flu observation (g-INFO).

    Science.gov (United States)

    Doan, Trung-Tung; Bernard, Aurélien; Da-Costa, Ana Lucia; Bloch, Vincent; Le, Thanh-Hoa; Legre, Yannick; Maigne, Lydia; Salzemann, Jean; Sarramia, David; Nguyen, Hong-Quang; Breton, Vincent

    2010-01-01

    The 2009 H1N1 outbreak has demonstrated that continuing vigilance, planning, and strong public health research capability are essential defenses against emerging health threats. Molecular epidemiology of influenza virus strains provides scientists with clues about the temporal and geographic evolution of the virus. In the present paper, researchers from France and Vietnam are proposing a global surveillance network based on grid technology: the goal is to federate influenza data servers and deploy automatically molecular epidemiology studies. A first prototype based on AMGA and the WISDOM Production Environment extracts daily from NCBI influenza H1N1 sequence data which are processed through a phylogenetic analysis pipeline deployed on EGEE and AuverGrid e-infrastructures. The analysis results are displayed on a web portal (http://g-info.healthgrid.org) for epidemiologists to monitor H1N1 pandemics.

  16. Security in a Replicated Metadata Catalogue

    CERN Document Server

    Koblitz, B

    2007-01-01

    The gLite-AMGA metadata has been developed by NA4 to provide simple relational metadata access for the EGEE user community. As advanced features, which will be the focus of this presentation, AMGA provides very fine-grained security also in connection with the built-in support for replication and federation of metadata. AMGA is extensively used by the biomedical community to store medical images metadata, digital libraries, in HEP for logging and bookkeeping data and in the climate community. The biomedical community intends to deploy a distributed metadata system for medical images consisting of various sites, which range from hospitals to computing centres. Only safe sharing of the highly sensitive metadata as provided in AMGA makes such a scenario possible. Other scenarios are digital libraries, which federate copyright protected (meta-) data into a common catalogue. The biomedical and digital libraries have been deployed using a centralized structure already for some time. They now intend to decentralize ...

  17. Dependable Distributed Computing for the International Telecommunication Union Regional Radio Conference RRC06

    CERN Document Server

    Moscicki, Jakub T; Lamanna, Massimo; Méndez, Patricia; Muraru, Adrian

    2009-01-01

    The International Telecommunication Union (ITU) Regional Radio Conference (RRC06) established in 2006 a new frequency plan for the introduction of digital broadcasting in European, African, Arab, CIS countries and Iran. The preparation of the plan involved complex calculations under short deadline and required dependable and efficient computing capability. The ITU designed and deployed in-situ a dedicated PC farm, in parallel to the European Organization for Nuclear Research (CERN) which provided and supported a system based on the EGEE Grid. The planning cycle at the RRC06 required a periodic execution in the order of 200,000 short jobs, using several hundreds of CPU hours, in a period of less than 12 hours. The nature of the problem required dynamic workload-balancing and low-latency access to the computing resources. We present the strategy and key technical choices that delivered a reliable service to the RRC06.

  18. Grid-added value to address malaria.

    Science.gov (United States)

    Breton, V; Jacq, N; Kasam, V; Hofmann-Apitius, M

    2008-03-01

    Through this paper, we call for a distributed, Internet-based collaboration to address one of the worst plagues of our present world, malaria. The spirit is a nonproprietary peer-production of information-embedding goods. And we propose to use the grid technology to enable such a worldwide "open-source" like collaboration. The first step toward this vision has been achieved during the summer 2005 on the enabling grids for E-scienceE (EGEE) grid infrastructure where 42 million ligands were docked for a total amount of 80 CPU years in 6 weeks in the quest for new drugs. The impact of this first deployment has significantly raised the interest of the research community so that several laboratories all around the world expressed interest to propose targets for a second large-scale deployment against malaria.

  19. Medical image registration algorithms assesment Bronze Standard application enactment on grids using the MOTEUR workflow engine

    CERN Document Server

    Glatard, T; Pennec, X

    2006-01-01

    Medical image registration is pre-processing needed for many medical image analysis procedures. A very large number of registration algorithms are available today, but their performance is often not known and very difficult to assess due to the lack of gold standard. The Bronze Standard algorithm is a very data and compute intensive statistical approach for quantifying registration algorithms accuracy. In this paper, we describe the Bronze Standard application and we discuss the need for grids to tackle such computations on medical image databases. We demonstrate MOTEUR, a service-based workflow engine optimized for dealing with data intensive applications. MOTEUR eases the enactment of the Bronze Standard and similar applications on the EGEE production grid infrastructure. It is a generic workflow engine, based on current standards and freely available, that can be used to instrument legacy application code at low cost.

  20. Symptom management in Behcets disease.

    Science.gov (United States)

    Ozel, Filiz; Tureyen, Aynur Esen; Aykar, Fisun Senuzun

    2018-01-01

    To determine the symptoms experienced by patients diagnosed with Behcet's Disease and how they cope with them. The qualitative study was conducted from September 2013 to March 2014 at Ege University Medical Faculty Hospital, Turkey, comprising patients having all symptoms of Behcet's Disease. Data was collected through semi-structured focus-group interview form. The findings were assessed using Theory of Unpleasant Symptoms and Symptom Management Theory. SPSS 20 and Nvivo 10 were used for data analysis. Of the 35 patients, 16(45.8%) were female and 19(54.2%) were male. The symptoms affected patients' lives, and the patients used either positive or negative symptom management strategies, leading to either positive or negative results during symptom management. Behcet's Disease patients needed effective symptom management.

  1. The Biometric Analysis of Pipefish Species from Çamaltı Lagoon (İzmir Bay, Aegean Sea).

    OpenAIRE

    Şule Gürkan

    2015-01-01

    Çamaltı Lagünü’ndeki (İzmir Körfezi, Ege Denizi) deniziğnelerinin biyometrik analizleri. Bu araştırma, 2000-2002 yılları arasında İzmir Körfezi Çamaltı Lagünündeki üç deniziğnesi türünün, Syngnathus acus Linneaus, 1758, Syngnathus typhle Linneaus, 1758 ve Nerophis ophidion (Linneaus 1758), biyometrik analizleri verilmiştir. Araştırmada toplam 562 adet birey incelenmiştir. S.acus ve S.typhle için 10 morfometrik, 5 meristik karakter, N.ophidion için ise 9 morfometrik 3 meristik karakter incelen...

  2. Migration of Monte Carlo simulation of high energy atmospheric showers to GRID infrastructure

    Energy Technology Data Exchange (ETDEWEB)

    Vazquez, Adolfo; Contreras, Jose Luis [Grupo de Altas EnergIas Departamento de Fisica Atomica, Molecular y Nuclear Universidad Complutense de Madrid Avenida Complutense s/n, 28040 Madrid - Spain (Spain); Calle, Ignacio de la; Ibarra, Aitor; Tapiador, Daniel, E-mail: avazquez@gae.ucm.e [INSA. IngenierIa y Servicios Aeroespaciales S.A. Paseo Pintor Rosales 34, 28008 Madrid - Spain (Spain)

    2010-04-01

    A system to run Monte Carlo simulations on a Grid environment is presented. The architectural design proposed uses the current resources of the MAGIC Virtual Organization on EGEE and can be easily generalized to support the simulation of any similar experiment, such as that of the future European planned project, the Cherenkov Telescope Array. The proposed system is based on a Client/Server architecture, and provides the user with a single access point to the simulation environment through a remote graphical user interface, the Client. The Client can be accessed via web browser, using web service technology, with no additional software installation on the user side required. The Server processes the user request and uses a database for both data catalogue and job management inside the Grid. The design, first production tests and lessons learned from the system will be discussed here.

  3. Amelogenesis imperfecta: the multidisciplinary approach. A case report.

    Science.gov (United States)

    Toksavul, Suna; Ulusoy, Mübin; Türkün, Murat; Kümbüloğlu, Ovül

    2004-01-01

    Amelogenesis imperfecta is a hereditary developmental disorder of the dental enamel, in both primary and permanent dentition. The main clinical characteristics are extensive loss of tooth tissue, poor esthetics, and tooth sensitivity. Transmission of the gene takes place by either autosomal, dominant X-linked, or recessive modes. This clinical report describes a treatment sequence based on a multidisciplinary approach. A 21-year-old girl with hypoplastic amelogenesis imperfecta was referred to the Ege University School of Dentistry clinic. She was concerned about the poor appearance and sensitivity of her teeth. The patient presented with an anterior open bite, although orthodontic treatment had been completed previously. Periodontal gingivectomy of her posterior teeth followed by endodontic treatment where indicated was proposed. The prosthodontic treatment consisted of metal ceramic fixed partial dentures of precious alloy. At the end of treatment, function and esthetics were improved to a level acceptable to both the patient and the dental team.

  4. IT Services Availability during the 2007 Annual CERN Closure

    CERN Multimedia

    IT Department

    2007-01-01

    Most of the physics, technical, administrative and communications services provided by the IT Department - including LCG (EGEE) production services - will remain available during the CERN annual closure (although EDH requests will stay queued). No interruptions are scheduled but in the event of failure, the restoration of services cannot be guaranteed. Problems will be dealt with on a best effort basis only. However, for the following services: Network, Databases, Mail, Web, Windows & Terminal Services, Indico, CDS, Grid (SAM, FTS, VOMS, GridView, Resource Brokers): experts should be reachable to start investigations within about half a day except around Christmas Eve and Christmas Day (24 and 25 December) and New Year’s Eve and New Year’s Day (31 December and 1 January). Incidents will be documented at http://cern.ch/ssb; The backup service: will remain operational, but backups cannot be guaranteed and file restores will not be possible; Castor: damaged tapes wi...

  5. Health-e-Child a grid platform for european paediatrics

    CERN Document Server

    Skaburskas, K; Shade, J; Manset, D; Revillard, J; Rios, A; Anjum, A; Branson, A; Bloodsworth, P; Hauer, T; McClatchey, R; Rogulin, D

    2008-01-01

    The Health-e-Child (HeC) project [1], [2] is an EC Framework Programme 6 Integrated Project that aims to develop a grid-based integrated healthcare platform for paediatrics. Using this platform biomedical informaticians will integrate heterogeneous data and perform epidemiological studies across Europe. The resulting Grid enabled biomedical information platform will be supported by robust search, optimization and matching techniques for information collected in hospitals across Europe. In particular, paediatricians will be provided with decision support, knowledge discovery and disease modelling applications that will access data in hospitals in the UK, Italy and France, integrated via the Grid. For economy of scale, reusability, extensibility, and maintainability, HeC is being developed on top of an EGEE/gLite [3] based infrastructure that provides all the common data and computation management services required by the applications. This paper discusses some of the major challenges in bio-medical data integr...

  6. DIRAC The Distributed MC Production and Analysis for LHCb

    CERN Document Server

    Bernet, R; Blouw, J; Brook, N; Charpentier, P; Closier, J; Egede, U; Frank, M; Gandelman, M; Garonne, V; Graciani-Díaz, R; Korolko, I; Kuznetsov, G; Patrick, G; Pickford, A; Romanovski, V G; Saborido-Silva, J J; Sánchez-García, M; Saroka, A; Stokes-Rees, I; Tobin, M; Tsaregorodtsev, A Yu; Vagnoni, V; Witek, M

    2005-01-01

    DIRAC is the LHCb distributed computing grid infrastructure for MC production and analysis. Its architecture is based on a set of distributed collaborating services. The service decomposition broadly follows the CERN/ARDA-RTAG proposal, which can eventually make possible the interchange of the EGEE/gLite and DIRAC components. In this paper we give an overview of the DIRAC architecture, as well as the main design choices in its implementation. The light nature and modular design of the DIRAC components allows its functionality to be easily extended to include new computing and storage elements or to handle new types of tasks. The DIRAC system already uses different types of computing resources - from single PC's to a variety of batch systems and to the Grid environment. In particular, the DIRAC interface to the LCG2 grid will be presented.

  7. DIRAC - The Distributed MC Production and Analysis for LHCb

    CERN Document Server

    AUTHOR|(CDS)2067410; Charpentier, P; Closier, J; Frank, M; Garonne, V; Witek, M; Romanovski, V; Egede, U; Vagnoni, V; Korolko, I; Blouw, J; Kuznetsov, G; Patrick, G; Gandelman, M; Graciani-Diaz, R; Bernet, R; Brook, N; Pickford, A; Tobin, M; Saroka, A; Stokes-Rees, I; Saborido-Silva, J; Sanchez-Garcia, M

    2004-09-30

    DIRAC is the LHCb distributed computing grid infrastructure for Monte Carlo (MC) production and analysis. Its architecture is based on a set of distributed collaborating services. The service decomposition broadly follows the CERN/ARDA-RTAG proposal, which should allow for the interchange of the EGEE/gLite and DIRAC components. In this paper we give an overview of the DIRAC architecture, as well as the main design choices in its implementation. The light nature and modular design of the DIRAC components allows its functionality to be easily extended to include new computing and storage elements or to handle new types of tasks. The DIRAC system already uses different types of computing resources - from single PC's to a variety of batch systems and to the Grid environment. In particular, the DIRAC interface to the LCG2 grid will be presented.

  8. Integrated reporting with CSR practices

    DEFF Research Database (Denmark)

    Lueg, Klarissa; Lueg, Rainer; Andersen, Karina

    2016-01-01

    Purpose: This study aims to illustrate how standards and guidelines for corporate social responsibility (CSR) can help a company in its integrated reporting (IR). We investigate the motivations of diverse stakeholders (including shareholders) in fostering the adoption of standards and guidelines...... and for controlling CSR implementation. However, the long and technical CSR reports did not effectively communicate EGE’s values and possibilities. We outline how EGE overcame these barriers. Contribution: We suggest that IR implementations depend on the context, and explain why the case company has opted to issue 2...... separate reports for their IR. Also, standardized approaches to CSR may be suitable for internal planning and control purposes. Yet, companies have to go beyond these measurements to achieve IR....

  9. gLExec and MyProxy integration in the ATLAS/OSG PanDA workload management system

    Science.gov (United States)

    Caballero, J.; Hover, J.; Litmaath, M.; Maeno, T.; Nilsson, P.; Potekhin, M.; Wenaus, T.; Zhao, X.

    2010-04-01

    Worker nodes on the grid exhibit great diversity, making it difficult to offer uniform processing resources. A pilot job architecture, which probes the environment on the remote worker node before pulling down a payload job, can help. Pilot jobs become smart wrappers, preparing an appropriate environment for job execution and providing logging and monitoring capabilities. PanDA (Production and Distributed Analysis), an ATLAS and OSG workload management system, follows this design. However, in the simplest (and most efficient) pilot submission approach of identical pilots carrying the same identifying grid proxy, end-user accounting by the site can only be done with application-level information (PanDA maintains its own end-user accounting), and end-user jobs run with the identity and privileges of the proxy carried by the pilots, which may be seen as a security risk. To address these issues, we have enabled PanDA to use gLExec, a tool provided by EGEE which runs payload jobs under an end-user's identity. End-user proxies are pre-staged in a credential caching service, MyProxy, and the information needed by the pilots to access them is stored in the PanDA DB. gLExec then extracts from the user's proxy the proper identity under which to run. We describe the deployment, installation, and configuration of gLExec, and how PanDA components have been augmented to use it. We describe how difficulties were overcome, and how security risks have been mitigated. Results are presented from OSG and EGEE Grid environments performing ATLAS analysis using PanDA and gLExec.

  10. Optimisation and validation of a 3D reconstruction algorithm for single photon emission computed tomography by means of GATE simulation platform; Optimisation et validation d'un algorithme de reconstruction 3D en Tomographie d'Emission Monophotonique a l'aide de la plate forme de simulation GATE

    Energy Technology Data Exchange (ETDEWEB)

    El Bitar, Ziad [Ecole Doctorale des Sciences Fondamentales, Universite Blaise Pascal, U.F.R de Recherches Scientifiques et Techniques, 34, avenue Carnot - BP 185, 63006 Clermont-Ferrand Cedex (France); Laboratoire de Physique Corpusculaire, CNRS/IN2P3, 63177 Aubiere (France)

    2006-12-15

    Although time consuming, Monte-Carlo simulations remain an efficient tool enabling to assess correction methods for degrading physical effects in medical imaging. We have optimized and validated a reconstruction method baptized F3DMC (Fully 3D Monte Carlo) in which the physical effects degrading the image formation process were modelled using Monte-Carlo methods and integrated within the system matrix. We used the Monte-Carlo simulation toolbox GATE. We validated GATE in SPECT by modelling the gamma-camera (Philips AXIS) used in clinical routine. Techniques of threshold, filtering by a principal component analysis and targeted reconstruction (functional regions, hybrid regions) were used in order to improve the precision of the system matrix and to reduce the number of simulated photons as well as the time consumption required. The EGEE Grid infrastructures were used to deploy the GATE simulations in order to reduce their computation time. Results obtained with F3DMC were compared with the reconstruction methods (FBP, ML-EM, MLEMC) for a simulated phantom and with the OSEM-C method for the real phantom. Results have shown that the F3DMC method and its variants improve the restoration of activity ratios and the signal to noise ratio. By the use of the grid EGEE, a significant speed-up factor of about 300 was obtained. These results should be confirmed by performing studies on complex phantoms and patients and open the door to a unified reconstruction method, which could be used in SPECT and also in PET. (author)

  11. Efficiency of ellagic acid and arbutin in melasma: a randomized, prospective, open-label study.

    Science.gov (United States)

    Ertam, Ilgen; Mutlu, Basak; Unal, Idil; Alper, Sibel; Kivçak, Bijen; Ozer, Ozgen

    2008-09-01

    The aim of this study was to compare the effectiveness of gel formulations containing arbutin, synthetic ellagic acid and plant extracts that contain ellagic acid, on patients with melasma. Thirty patients who applied to Ege University Medical Faculty, Department of Dermatology, were included in the study. A signed consent was obtained from each patient prior to study. Patients whose type of melasma was determined via Wood's lamp were randomized to groups of arbutin, synthetic ellagic acid and plant extract containing natural ellagic acid. The pigment density of patients was evaluated via Mexameter before and after the treatment. The approval of the Institutional Ethics Committee of Ege University was obtained before the study. Wilcoxon and Kruskal-Wallis tests were used in the statistical analysis. Nine of 10 patients, for whom synthetic ellagic acid was started, completed the study. A decrease in the level of melanin was determined in eight of these nine patients (P = 0.038). A significant decrease in the level of melanin was also determined in all 10 patients who used plant extract containing ellagic acid (P = 0.05). A significant response was obtained from all of 10 patients who used arbutin. The difference between pre- and post-treatment levels of melanin was statistically significant (P = 0.05). Formulations prepared with plant extracts containing ellagic acid was found effective on melasma, similar to the formulations containing synthetic ellagic acid and arbutin. This material that is not yet being used widespread commercially on melasma could be an effective alternative for treatment of melasma.

  12. VOMS/VOMRS utilization patterns and convergence plan

    Science.gov (United States)

    Ceccanti, A.; Ciaschini, V.; Dimou, M.; Garzoglio, G.; Levshina, T.; Traylen, S.; Venturi, V.

    2010-04-01

    The Grid community uses two well-established registration services, which allow users to be authenticated under the auspices of Virtual Organizations (VOs). The Virtual Organization Membership Service (VOMS), developed in the context of the Enabling Grid for E-sciencE (EGEE) project, is an Attribute Authority service that issues attributes expressing membership information of a subject within a VO. VOMS allows to partition users in groups, assign them roles and free-form attributes which are then used to drive authorization decisions. The VOMS administrative application, VOMS-Admin, manages and populates the VOMS database with membership information. The Virtual Organization Management Registration Service (VOMRS), developed at Fermilab, extends the basic registration and management functionalities present in VOMS-Admin. It implements a registration workflow that requires VO usage policy acceptance and membership approval by administrators. VOMRS supports management of multiple grid certificates, and handling users' request for group and role assignments, and membership status. VOMRS is capable of interfacing to local systems with personnel information (e.g. the CERN Human Resource Database) and of pulling relevant member information from them. VOMRS synchronizes the relevant subset of information with VOMS. The recent development of new features in VOMS-Admin raises the possibility of rationalizing the support and converging on a single solution by continuing and extending existing collaborations between EGEE and OSG. Such strategy is supported by WLCG, OSG, US CMS, US Atlas, and other stakeholders worldwide. In this paper, we will analyze features in use by major experiments and the use cases for registration addressed by the mature single solution.

  13. VOMS/VOMRS utilization patterns and convergence plan

    Energy Technology Data Exchange (ETDEWEB)

    Ceccanti, A.; /INFN, CNAF; Ciaschini, V.; /INFN, CNAF; Dimou, M.; /CERN; Garzoglio, G.; /Fermilab; Levshina, T.; /Fermilab; Traylen, S.; /CERN; Venturi, V.; /INFN, CNAF

    2010-01-01

    The Grid community uses two well-established registration services, which allow users to be authenticated under the auspices of Virtual Organizations (VOs). The Virtual Organization Membership Service (VOMS), developed in the context of the Enabling Grid for E-sciencE (EGEE) project, is an Attribute Authority service that issues attributes expressing membership information of a subject within a VO. VOMS allows to partition users in groups, assign them roles and free-form attributes which are then used to drive authorization decisions. The VOMS administrative application, VOMS-Admin, manages and populates the VOMS database with membership information. The Virtual Organization Management Registration Service (VOMRS), developed at Fermilab, extends the basic registration and management functionalities present in VOMS-Admin. It implements a registration workflow that requires VO usage policy acceptance and membership approval by administrators. VOMRS supports management of multiple grid certificates, and handling users' request for group and role assignments, and membership status. VOMRS is capable of interfacing to local systems with personnel information (e.g. the CERN Human Resource Database) and of pulling relevant member information from them. VOMRS synchronizes the relevant subset of information with VOMS. The recent development of new features in VOMS-Admin raises the possibility of rationalizing the support and converging on a single solution by continuing and extending existing collaborations between EGEE and OSG. Such strategy is supported by WLCG, OSG, US CMS, US Atlas, and other stakeholders worldwide. In this paper, we will analyze features in use by major experiments and the use cases for registration addressed by the mature single solution.

  14. Lucy's back: Reassessment of fossils associated with the A.L. 288-1 vertebral column.

    Science.gov (United States)

    Meyer, Marc R; Williams, Scott A; Smith, Michael P; Sawyer, Gary J

    2015-08-01

    The Australopithecus afarensis partial skeleton A.L. 288-1, popularly known as "Lucy" is associated with nine vertebrae. The vertebrae were given provisional level assignments to locations within the vertebral column by their discoverers and later workers. The continuity of the thoracic series differs in these assessments, which has implications for functional interpretations and comparative studies with other fossil hominins. Johanson and colleagues described one vertebral element (A.L. 288-1am) as uniquely worn amongst the A.L. 288-1 fossil assemblage, a condition unobservable on casts of the fossils. Here, we reassess the species attribution and serial position of this vertebral fragment and other vertebrae in the A.L. 288-1 series. When compared to the other vertebrae, A.L. 288-1am falls well below the expected size within a given spinal column. Furthermore, we demonstrate this vertebra exhibits non-metric characters absent in hominoids but common in large-bodied papionins. Quantitative analyses situate this vertebra within the genus Theropithecus, which today is solely represented by the gelada baboon but was the most abundant cercopithecoid in the KH-1s deposit at Hadar where Lucy was discovered. Our additional analyses confirm that the remainder of the A.L. 288-1 vertebral material belongs to A. afarensis, and we provide new level assignments for some of the other vertebrae, resulting in a continuous articular series of thoracic vertebrae, from T6 to T11. This work does not refute previous work on Lucy or its importance for human evolution, but rather highlights the importance of studying original fossils, as well as the efficacy of the scientific method. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Dental metric assessment of the omo fossils: implications for the phylogenetic position of Australopithecus africanus.

    Science.gov (United States)

    Hunt, K; Vitzthum, V J

    1986-10-01

    The discovery of Australopithecus afarensis has led to new interpretations of hominid phylogeny, some of which reject A. africanus as an ancestor of Homo. Analysis of buccolingual tooth crown dimensions in australopithecines and Homo species by Johanson and White (Science 202:321-330, 1979) revealed that the South African gracile australopithecines are intermediate in size between Laetoli/hadar hominids and South African robust hominids. Homo, on the other hand, displays dimensions similar to those of A. afarensis and smaller than those of other australopithecines. These authors conclude, therefore, that A. africanus is derived in the direction of A. robustus and is not an ancestor of the Homo clade. However, there is a considerable time gap (ca. 800,000 years) between the Laetoli/Hadar specimens and the earliest Homo specimens; "gracile" hominids from Omo fit into this chronological gap and are from the same geographic area. Because the early specimens at Omo have been designated A. afarensis and the later specimens classified as Homo habilis, Omo offers a unique opportunity to test hypotheses concerning hominid evolution, especially regarding the phylogenetic status of A. africanus. Comparisons of mean cheek teeth breadths disclosed the significant (P less than or equal to 0.05) differences between the Omo sample and the Laetoli/Hadar fossils (P4, M2, and M3), the Homo fossils (P3, P4, M1, M2, and M1), and A. africanus (M3). Of the several possible interpretations of these data, it appears that the high degree of similarity between the Omo sample and the South African gracile australopithecine material warrants considering the two as geographical variants of A. africanus. The geographic, chronologic, and metric attributes of the Omo sample argue for its lineal affinity with A. afarensis and Homo. In conclusion, a consideration of hominid postcanine dental metrics provides no basis for removing A. africanus from the ancestry of the Homo lineage.

  16. Limits of I-models Principles Application on Czech SMEs'’ Internationalization Process

    Directory of Open Access Journals (Sweden)

    Lea Kubíčková

    2014-01-01

    Full Text Available Internationalization process of small and medium sized enterprises is examined often in an effort to get detailed description of particular stages of this process. There are many authors who deal with the internationalization process theories. The most popular theory is so-called Uppsala Model (Johanson, Vahlne, 1977. Very popular is also a group of models based on theory of innovations, called I-models (Bilkey, Tesar, 1977. These models are based on the idea that the process of internationalization is gradual, sequential process built on innovative decisions relating to new company’s needs, possibilities or new resources. The aim of this paper is to apply I-models principles on the internationalization process of Czech SMEs. There were processed data from the survey conducted in 2009-2012. The data were obtained from 385 Czech SMEs operating in the field of engineering, constructing, wood processing industry, food industry and viticulture. To apply the basic principles of the I-models to internationalization process of Czech SMEs it was necessary to determine if there are so-called Born Globals which deny the I-model’s internationalization theories. It was necessary to examine motives of internationalization of Czech SMEs, to prove dependency between the number of years on the market and proactivity/reactivity of the motives for entering foreign markets. Processing obtained data did not enable to unequivocally confirm that the basic principles forming a keystone of the I-models are functional in the internationalization process of Czech SMEs.

  17. The next three decades of the comet assay: a report of the 11th International Comet Assay Workshop.

    Science.gov (United States)

    Koppen, Gudrun; Azqueta, Amaya; Pourrut, Bertrand; Brunborg, Gunnar; Collins, Andrew R; Langie, Sabine A S

    2017-05-01

    The International Comet Assay Workshops are a series of scientific conferences dealing with practical and theoretical aspects of the Comet Assay (single-cell gel electrophoresis)-a simple method for detecting DNA strand breaks. The first paper describing such an assay was published over 30 years ago in 1984 by Swedish researchers O. Ostling and K. J. Johanson. Appropriately, the theme for the 2015 meeting was looking to the future: 'The Next 3 Decades of the Comet Assay'. The programme included 25 oral and 43 poster presentations depicting the latest advances in technical developments as well as applications of the comet assay in genotoxicity testing (in vitro and in vivo) and biomonitoring of both humans and the environment. Open discussion sessions based on questions from the participants allowed exchange of practical details on current comet assay protocols. This report summarises technical issues of high importance which were discussed during the sessions. We provide information on ways to improve the assay performance, by testing for cytotoxicity, by using reference samples to reduce or allow for inter-experimental variation, and by standardising quantification of the damage, including replicates and scoring enough comets to ensure statistical validity. After 30 years of experimentation with the comet assay, we are in a position to control the important experimental parameters and make the comet assay a truly reliable method with a wealth of possible applications. © The Author 2017. Published by Oxford University Press on behalf of the UK Environmental Mutagen Society. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  18. Is a fatty pancreas a banal lesion?

    Directory of Open Access Journals (Sweden)

    Andrzej Smereczyński

    2016-09-01

    Full Text Available So far, a fatty pancreas has been related to obesity and the ageing processes in the body. The current list of pathogenetic factors of the condition is clearly extended with genetically conditioned diseases (cystic fibrosis, Shwachman-Diamond syndrome and Johanson-Blizzard syndrome, pancreatitis, especially hereditary and obstructive, metabolic and hormonal disorders (hypertriglyceridemia, hypercholesterolemia, hyperinsulinemia and hypercortisolemia, alcohol overuse, taking some medicines (especially adrenal cortex hormones, disease of the liver and visceral adiposis. As regards lipomatosis of that organ resulting mainly from dyslipidemia and hyperglycemia, the term “nonalcoholic fatty pancreas disease” was introduced. Experimental studies on animals and histological preparations of the pancreatic fragments show that the lipotoxicity of the collected adipocytes collected ion the organ release a cascade of proinflammatory phenomena, and even induces the processes of carcinogenesis. Pancreas adiposis is best defined in Computed Tomography and Magnetic Resonance Imaging. However, a series of works proved the usefulness in the diagnostics of that pathology of transabdominal and endoscopic ultrasonography. In that method, the degree of adiposis was based on the comparison of echogenicity of the pancreas and the liver, renal parenchyma, spleen and/or retroperitoneal adipose. Recently, the evaluation was expanded by the evaluation of the degree of pancreatic adipose with the pancreas-to-liver index, utilizing to that end a special computer program. According to our experience, the simplest solution is the method utilized by us. On one crosssection of the body of the pancreas, its echogenicity is assessed in comparison to retroperitoneal adipose and the visibility of the splenic vein, pancreatic duct and the major retroperitoneal vessels. Depending on the visualization of these structures, it is possible to determine the degree of pancreas adiposis

  19. The Climate-G Portal: a scientific gateway for climate change

    Science.gov (United States)

    Fiore, S.; Aloisio, G.; Blower, J. D.; Cofino, A.; Denvil, S.; Fox, P. A.; Petitdidier, M.; Schwichtenberg, H.

    2010-12-01

    Climate-G is a data-oriented research effort conceived in the context of the EGEE Earth Science Cluster and devoted to the Climate Change community. The testbed is an interdisciplinary effort joining expertise in the field of climate change and computational science. The main goal of Climate-G is to allow scientists carrying out geographical and cross-institutional data discovery, access, visualization and sharing of climate data. The involved partners are: Centro Euro-Mediterraneo per i Cambiamenti Climatici (CMCC, Italy), Institut Pierre-Simon Laplace (IPSL/CNRS, France), Fraunhofer Institut für Algorithmen und Wissenschaftliches Rechnen (SCAI, Germany), National Center for Atmospheric Research (NCAR, USA) and Rensselaer Polytechnic Institute (RPI, USA), University of Reading (Reading, UK), University of Cantabria (UC, Spain), and University of Salento (UniSalento, Italy). The main results of this testbed are the distributed data/metadata architecture (exploiting the GRelC service) and the scientific gateway of the testbed (Climate-G Portal). The latter is a central topic of this contribution. Data distribution comes from the need of sharing data among centres without moving it into a central repository. Each partner can contribute with new datasets to the testbed just adding a new data service into the infrastructure and mapping it on a specific metadata server. The metadata management plays a critical role in such a distributed environment, since it enables search and discovery activities, allows describing and cataloguing datasets, makes data effectively accessible and shareable by the scientific community. The novel grid enabled harvesting system will be presented and discussed showing a map-enabled search page providing aggregated metadata information. Climate-G exploits both grid technologies connected with the EGEE project and domain-based tools and services. The general grid services provide a solid basis at an infrastructural level ensuring great

  20. CMR in patients with severe myocarditis: diagnostic value of quantitative tissue markers including extracellular volume imaging.

    Science.gov (United States)

    Radunski, Ulf K; Lund, Gunnar K; Stehning, Christian; Schnackenburg, Bernhard; Bohnen, Sebastian; Adam, Gerhard; Blankenberg, Stefan; Muellerleile, Kai

    2014-07-01

    This study evaluated the accuracy of T2, T1, and extracellular volume (ECV) quantification as novel quantitative tissue markers in comparison with standard "Lake-Louise" cardiac magnetic resonance (CMR) criteria to diagnose myocarditis. Novel approaches using T2 and T1 mapping may overcome the limitations of signal intensity-based parameters, which would potentially result in a better diagnostic accuracy compared with standard CMR techniques in suspected myocarditis. CMR was performed in 104 patients with myocarditis and 21 control subjects at 1.5-T. Patients with myocarditis underwent CMR 2 weeks (interquartile range: 1 to 7 weeks) after presentation with new-onset heart failure (n = 66) or acute chest pain (n = 38). T2 and T1 mapping were implemented into a standard protocol including T2-weighted (T2w), early gadolinium enhancement (EGE) CMR, and late gadolinium enhancement (LGE) CMR. T2 quantification was performed using a free-breathing, navigator-gated multiecho sequence. T1 quantification was performed using the modified Look-Locker inversion recovery sequence before and after administration of 0.075 mmol/kg gadobenate dimeglumine. T2, T1, and ECV maps were generated using a plug-in for the OsiriX software (Pixmeo, Bernex, Switzerland) to calculate mean global myocardial T2, T1, and ECV values. The diagnostic accuracies of conventional CMR were 70% (95% confidence interval [CI]: 61% to 77%) for T2w CMR, 59% (95% CI: 56% to 73%) for EGE, and 67% (95% CI: 59% to 75%) for LGE. The diagnostic accuracies of mapping techniques were 63% (95% CI: 53% to 73%) for myocardial T2, 69% (95% CI: 60% to 76%) for native myocardial T1, and 76% (95% CI: 68% to 82%) for global myocardial ECV. The diagnostic accuracy of CMR was significantly improved to 90% (95% CI: 84% to 95%) by a stepwise approach, using the presence of LGE and myocardial ECV ≥27% as diagnostic criteria, compared with 79% (95% CI: 71% to 85%; p = 0.0043) for the Lake-Louise criteria. In patients

  1. Future Events

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    1997-04-01

    Full Text Available 1\tThird International Conference “Health and Human Rights” 13-15 Octobre 1997 Gaza,Gaza Community Mental Health Programme PO BOX 1049 Gaza City. Palestine Tel:972 7 865949, Fax: 972 7 824072, Email: gcmhp @( baraka.org 2\tÇocuk İstismarının ve İhmalinin Önlenmesi Semineri. 8-9 Eylül 1997 Kemer Antalya. Prof.Dr.Esin Konanç, Eğitim Bilimleri Fakültesi Cebeci, Ankara Tel: 0312 491 11 81- 363 33 50-59 Fax: 0312 363 6l 45 3\tIV.Pratisyen Hekimlik Kongresi, 29 Ekim-2 Kasım 1997, İzmir, Pratisyen Hekimlik Kongresi Düzenleme Kurulu Mithatpaşa Caddesi No:62/18, 06420, Yenişehir, Ankara Tel: 0312 4183156; 4183963 Faks: 0312 4172672 4\tAmerican Academy of Forensic Sciences, 50th Annual Meeting February 9-14 February 1998 San Francisco, CA P.O. Box 669 Colorado Springs, CO 80901-0669 5\tIII Adli Bilimler Kongresi 14-17 Nisan 1998, Kuşadası. Prof.Dr.Beyhan Ege Ege Üniversitesi Tıp Fak. Adli Tıp Anabilim Dalı 35100 Bornova İzmir Tel: 0232 343 43 43 Fax: 0232 388 00 09 6\t6th Indo Pacific Congress on Legal Medicine and Forensic Sciences (INPALMS- 1998-KOBE 26-30 July, 1998, Kobe, Japan Simul International, Inc., Kansai Office Kogin Bldg., Annex 8F, 4-2-7 Koraibashi, Chuo-ku, Osaka 541, Japan Tel: 81-6-231-2441 Fax: 81-6-231-2447 7\t15th Meeting of the International Association of Forensic Science 22-28 August 1999, University of California, Los Angeles. Barry Fisher IAFS-1999 c/o LASD/SSB 2020 W.Beverly Blvd, Los Angeles, CA 90057 USA Email:73233-3344@compuserve.com http://www. criminalistics. com ./IAFS-1999

  2. arcControlTower: the System for Atlas Production and Analysis on ARC

    Science.gov (United States)

    Filipčič, Andrej; ATLAS Collaboration

    2011-12-01

    PanDA, the Atlas management and distribution system for production and analysis jobs on EGEE and OSG clusters, is based on pilot jobs to increase the throughput and stability of the job execution on grid. The ARC middleware uses a specific approach which tightly connects the job requirements with cluster capabilities like resource usage, software availability and caching of input files. The pilot concept renders the ARC features useless. The arcControlTower is the job submission system which merges the pilot benefits and ARC advantages. It takes the pilot payload from the panda server and submits the jobs to the Nordugrid ARC clusters as regular jobs, with all the job resources known in advance. All the pilot communication with the PanDA server is done by the arcControlTower, so it plays the role of a pilot factory and the pilot itself. There are several advantages to this approach: no grid middleware is needed on the worker nodes, the fair-share between the production and user jobs is tuned with the arcControlTower load parameters, the jobs can be controlled by ARC client tools. The system could be extended to other submission systems using central distribution.

  3. Molecular analysis of abnormal hemoglobins in beta chain in Aegean region of Turkey and first reports of hemoglobin Andrew-Minneapolis and Hb Hinsdale from Turkey.

    Science.gov (United States)

    Aykut, Ayça; Onay, Hüseyin; Durmaz, Asude; Karaca, Emin; Vergin, Canan; Aydınok, Yeşim; Özkınay, Ferda

    2015-07-01

    The Agean is one of the regions in Turkey where thalassemias and abnormal hemoglobins (Hbs) are prevalent. Combined heterozygosity of thalassemia mutations with a variety of structural Hb variants lead to an extremely wide spectrum of clinical and hematological phenotypes which is of importance for prenatal diagnosis. One hundred and seventeen patients and carriers diagnosed by hemoglobin electrophoresis (HPLC), at risk for abnormal hemoglobinopathies were screened for mutational analysis of the beta-globin gene. The full coding the 5' UTR, and the 3' UTR sequences of beta-globin gene (GenBank accession no. U01317) were amplified and sequenced. In this study, a total of 118 (12.24%) structural Hb variant alleles were identified in 1341 mutated beta-chain alleles in Medical Genetics Department of Ege University between January 2006 and November 2013. Here, we report the mutation spectrum of abnormal Hbs associated with the beta-globin gene in Aegean region of Turkey. In the present study, the Hb Hinsdale and Hb Andrew-Minneapolis variants are demonstrated for the first time in the Turkish population.

  4. Ascidianlar ve Akdeniz Havzasındaki Dağılımları.

    Directory of Open Access Journals (Sweden)

    Herdem Aslan

    2015-12-01

    Full Text Available Bu çalışma Ege Denizi’nin kuzeydoğusunda bulunan Bozcaada kıyılarının Ascidian faunası ve bazı ekolojik özelliklerini ortaya çıkarmak için yapılmıştır. Dünya denizlerinde 2500’den fazla tür ile temsil edilen Ascidian türleri infralittoral zondan hadal zona kadar geniş bir alanda sessil olarak yaşarlar. Ülkemiz sularında dağılımları hakkında çok az bilgiye sahip olduğumuz Ascidianların Doğu Akdeniz’den 86, Batı Akdeniz’den 165 türü bilinmektedir. Bu çalışmada ise 2000-2001 yıllarında Bozcaada’nın ifralittoralinde beam trol, drej ve spatula kullanılarak altı Ascidian türü (Aplidium conicum (Olivi, 1792, Didemnum maculosum (Milne-Edwards,1841, Ascidiella aspersa (Müller, 1776, Ascidia mentula Müller, 1776, Styela plicata (Lesueur, 1823, Molgula manhattensis (De Kay, 1841 elde edilmiştir

  5. Academic Dishonesty Tendencies and Values of Teacher Candidates

    Directory of Open Access Journals (Sweden)

    Ayşegül KADI

    2016-12-01

    Full Text Available The purpose of this study was to examine the values and academic dishonesty tendencies of teacher candidates. The population of this study included teacher candidates who received pedagogic formation education during 2013-2014 academic semester at the Faculty of Education at Ege University. The study was conducted with 244 teacher candidates, who were chosen through convenient sampling method. Academic Dishonesty Tendency Scale and Portrait Values Questionnaire were used to collect data. It was a correlational study due to the investigation of the relationship between values and academic dishonesty tendencies of teacher candidates. It was also a survey study since the academic dishonesty tendencies and values of teacher candidates were examined in relation to demographic variables. The results suggested that there wass a significant difference between the values and academic dishonesty tendencies of teacher candidates for gender variable. The values and academic dishonesty tendencies of teacher candidates did not differ for different fields of study. There was not a significant relationship between the academic dishonesty tendencies and values of teacher candidates.

  6. Türk Patolojisinde Bir Okul Prof Dr Talia Bali Aykan 13 Ağustos 1918 - 31 Ağustos 2003

    OpenAIRE

    Aydın Sav

    2003-01-01

    Aydın SAV Ege Üniversitesi mezunu bir doktor olarak, öğrenciliğimde bana patoloji dalını sevdirmiş hocalarımı ardımda bırakıp, bu alanda uzmanlık eğitimimi yapmak üzere birçok kapıyı çaldıktan soma ilk defa 1980 yılında “Talia Hoca”yla karşılaştım. Bu ilk mülakatımızda, beni dinleyip merakla bu mesleği neden seçtiğimi sormasıyla “mikroskobun içinden bir mikrofon sarkıtıp hücrelerle röportaj yapmak istediğim için” dediğimi hatırlıyorum. Hoca bana dönüp “İstanbul'da bir kalacak ...

  7. Matchmaking, datasets and physics analysis

    CERN Document Server

    Donno, Flavia; Eulisse, Giulio; Mazzucato, Mirco; Steenberg, Conrad; CERN. Geneva. IT Department; 10.1109/ICPPW.2005.48

    2005-01-01

    Grid enabled physics analysis requires a workload management system (WMS) that takes care of finding suitable computing resources to execute data intensive jobs. A typical example is the WMS available in the LCG2 (also referred to as EGEE-0) software system, used by several scientific experiments. Like many other current grid systems, LCG2 provides a file level granularity for accessing and analysing data. However, application scientists such as high energy physicists often require a higher abstraction level for accessing data, i.e. they prefer to use datasets rather than files in their physics analysis. We have improved the current WMS (in particular the Matchmaker) to allow physicists to express their analysis job requirements in terms of datasets. This required modifications to the WMS and its interface to potential data catalogues. As a result, we propose a simple data location interface that is based on a Web service approach and allows for interoperability of the WMS with new dataset and file catalogues...

  8. Biotechnology and human dignity: a European perspective.

    Science.gov (United States)

    Agius, Emmanuel

    2011-01-01

    The precise meaning of "human dignity" is increasingly being questioned in ethics and law Is human dignity an adequate guide to policymaking in today's biotechnological era? This article is an attempt to answer this thorny issue. The emergence of the concept of human dignity as a key point of reference for the regulation of modern science and technology in the European Union is evaluated. The main contribution of this article is to prove that in EU Directives and Recommendations, human dignity is not an elusive concept but rather a regulatory restraint in European public policies on biotechnology, particularly through the influence of the European Group on Ethics in Science and New Technologies (EGE). Two examples will be elaborated to prove this claim: first, the issue of intellectual property in biotechnological inventions, and secondly the funding of research proposals involving the use of human embryonic stem cells. These examples prove that the principle of human dignity is not an empty concept as some philosophers and bioethicists claim but rather a normative guideline that is shaping European policies on biotechnology.

  9. Changes in physical conditions of a coarse textured soil by addition of organic wastes

    Directory of Open Access Journals (Sweden)

    Melis Cercioglu

    2014-01-01

    Full Text Available Effects of composted tobacco waste, chicken manure and bio-humus applied during a period of three years on a coarse textured soil (Typic Xerofluvent at Agriculture Faculty’s Research and Practise Farmyard of Ege University located on Menemen plain (Izmir, Turkey on soil physical properties were studied. The experiment was arranged in a randomized block design on 16 plots with four replications. Each plot size was 5x3 m2. Composted tobacco waste (CTW from cigarette industry and chicken manure (CM and bio-humus (BH from plant residuals were applied at rates of 50 t ha-1, 4 t ha-1, 10 t ha-1,respectively. Inorganic fertilizers (N-P-K are also added with chicken manure and bio-humus plots. Tobacco wastes obtained from cigarette industry were used after composting. The addition of organic wastes resulted in a significant (p≤0.05 decrease in bulk density (BD; increase in porosity (PO, field capacity (FC, wilting point (WP, available water content (AWC and structure stability index (SSI of soil samples when compared to the control.

  10. Examining the Relationship between Superstitious Behavior in Sport and Trait Anxiety Levels among College Students Engaged in Active Sports

    Directory of Open Access Journals (Sweden)

    Utku Işık

    2015-04-01

    Full Text Available The purpose of this study was to examine the relationship between superstitious behavior in sport and trait anxiety levels among college students engaged in active sports. 166 Pamukkale University and Ege University of School of Physical Education and Sports students who are selected simple random sampling method voluntarily participated (61 females and 105 males for the study. In the study for gathering data “Superstitious Ritual Questionnaire” and “Trait Anxiety Inventory” were used together. To examine the relationship between superstitious behavior in sport and trait anxiety levels the Pearson product-moment coefficients of correlation was used. The results indicated that the relationship between superstitious behavior in sport and trait anxiety level is positive and statistically significant (r=.208; p=.007. To explain whether there are significant differences between participants’ superstitious behavior in sport according to gender, Independent Sample T-test was used. Result of this analysis revealed no statistically significant difference between male and female students tendency to superstitious behaviors according to gender (t=1.15; p=.251. In conclusion study findings showed that anxiety is a factor that increases university students, engaging in active sport, superstitions behavior.

  11. [Mobbing: between personality traits and organizational-managerial characteristics of the occupational environment].

    Science.gov (United States)

    Fenga, Concettina; Platania, Chiara Anna; Di Rosa, Antonio; Alibrandi, Angela; De Luca, Annamaria; Barresi, Gaetano; Di Nola, Carmelina; Cacciola, Anna

    2012-01-01

    INTRODUCTION. The relationship between stressful events in the workplace and their effect on health is the subject of numerous studies where the phenomenon of"Mobbing" has become of increasing interest in Social Psychiatry and Occupational Medicine. The aim of this study is to evaluate the relationship between mobbing, occupational stress and personality structure in a group of persons who consulted the "Work Adaptation Disorders Centre" at the Institute of Occupational Medicine between December 2008 and June 2010 for mobbing-related issues. Referring to Leymann Inventory of Psychological Terrorization (LIPT), H. Ege, Occupational Stress Indicator (OSI), Minnesota Multiphasic Personality Inventory 2 (MMPI-2), it has been possible to assess situations of harassment, the sources and the effects of work stress, as well as personality traits in the study group. The results showed that high levels of occupational stress and inadequate coping strategies can lead to depressive, hysterical and paranoid manifestations. Although the relationship between mobbing, occupational stress and personality traits still remains controversial, there is an association between perception of adverse behaviour and mental health, regardless of the subject's ability to cope with stressful life events. The data seem to confirm that the prevention of bullying must be implemented by the work organization and by handling interpersonal conflicts in the work context.

  12. Sustaining and Extending the Open Science Grid: Science Innovation on a PetaScale Nationwide Facility (DE-FC02-06ER41436) SciDAC-2 Closeout Report

    Energy Technology Data Exchange (ETDEWEB)

    Livny, Miron [Univ. of Wisconsin, Madison, WI (United States); Shank, James [Boston Univ., MA (United States); Ernst, Michael [Brookhaven National Lab. (BNL), Upton, NY (United States); Blackburn, Kent [California Inst. of Technology (CalTech), Pasadena, CA (United States); Goasguen, Sebastien [Clemson Univ., SC (United States); Tuts, Michael [Columbia Univ., New York, NY (United States); Gibbons, Lawrence [Cornell Univ., Ithaca, NY (United States); Pordes, Ruth [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); Sliz, Piotr [Harvard Medical School, Boston, MA (United States); Deelman, Ewa [Univ. of Southern California, Los Angeles, CA (United States). Information Sciences Inst.; Barnett, William [Indiana Univ., Bloomington, IN (United States); Olson, Doug [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); McGee, John [Univ. of North Carolina, Chapel Hill, NC (United States). Renaissance Computing Inst.; Cowles, Robert [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wuerthwein, Frank [Univ. of California, San Diego, CA (United States); Gardner, Robert [Univ. of Chicago, IL (United States); Avery, Paul [Univ. of Florida, Gainesville, FL (United States); Wang, Shaowen [Univ. of Illinois, Champaign, IL (United States); Univ. of Iowa, Iowa City, IA (United States); Lincoln, David Swanson [Univ. of Nebraska, Lincoln, NE (United States)

    2015-02-11

    Under this SciDAC-2 grant the project’s goal w a s t o stimulate new discoveries by providing scientists with effective and dependable access to an unprecedented national distributed computational facility: the Open Science Grid (OSG). We proposed to achieve this through the work of the Open Science Grid Consortium: a unique hands-on multi-disciplinary collaboration of scientists, software developers and providers of computing resources. Together the stakeholders in this consortium sustain and use a shared distributed computing environment that transforms simulation and experimental science in the US. The OSG consortium is an open collaboration that actively engages new research communities. We operate an open facility that brings together a broad spectrum of compute, storage, and networking resources and interfaces to other cyberinfrastructures, including the US XSEDE (previously TeraGrid), the European Grids for ESciencE (EGEE), as well as campus and regional grids. We leverage middleware provided by computer science groups, facility IT support organizations, and computing programs of application communities for the benefit of consortium members and the US national CI.

  13. Hepatic adverse events during highly active antiretroviral therapy containing nevirapine: a case report

    Directory of Open Access Journals (Sweden)

    Yamazhan Tansu

    2002-09-01

    Full Text Available Abstract Background Hepatotoxicity is one of the most serious complications of highly active antiretroviral therapy (HAART. The aim of this report is to analyse an HIV infected patient on HAART including nevirapine and taking antidepressive agents, with acute toxic hepatitis. Case presentation A 39 year old patient diagnosed as HIV positive one month ago administered to the clinical ward of the Department of Infectious Diseases and Clinical Microbiology in Ege University Medical School with high fever, malaise, nausea, diarrheae and elevated liver enzymes (ALT 1558 U/L, AST 4288 U/L. He has been using HAART including zidovudine+lamivudine (2 × 1/day and nevirapine (2 × 200 mg/day, following dose escalation for 22 days, sertralin and diazepam for 12 days and lithium for 10 days. The patient was hospitalized. Antiretroviral and antidepressant treatments were stopped. The day after admission, his fever dropped and his symptoms improved. Clinical improvement continued on the following days. The patient was discharged upon his request on the 14th day of hospitalization. The liver function tests returned to normal levels in two weeks following discharge. Conclusion Close monitoring of liver enzymes during the first 12 weeks of nevirapine therapy is critical to prevent life threatening events.

  14. Integrating Xgrid into the HENP distributed computing model

    Science.gov (United States)

    Hajdu, L.; Kocoloski, A.; Lauret, J.; Miller, M.

    2008-07-01

    Modern Macintosh computers feature Xgrid, a distributed computing architecture built directly into Apple's OS X operating system. While the approach is radically different from those generally expected by the Unix based Grid infrastructures (Open Science Grid, TeraGrid, EGEE), opportunistic computing on Xgrid is nonetheless a tempting and novel way to assemble a computing cluster with a minimum of additional configuration. In fact, it requires only the default operating system and authentication to a central controller from each node. OS X also implements arbitrarily extensible metadata, allowing an instantly updated file catalog to be stored as part of the filesystem itself. The low barrier to entry allows an Xgrid cluster to grow quickly and organically. This paper and presentation will detail the steps that can be taken to make such a cluster a viable resource for HENP research computing. We will further show how to provide to users a unified job submission framework by integrating Xgrid through the STAR Unified Meta-Scheduler (SUMS), making tasks and jobs submission effortlessly at reach for those users already using the tool for traditional Grid or local cluster job submission. We will discuss additional steps that can be taken to make an Xgrid cluster a full partner in grid computing initiatives, focusing on Open Science Grid integration. MIT's Xgrid system currently supports the work of multiple research groups in the Laboratory for Nuclear Science, and has become an important tool for generating simulations and conducting data analyses at the Massachusetts Institute of Technology.

  15. Risk factors for renal scarring in children with primary vesicoureteral reflux disease

    Directory of Open Access Journals (Sweden)

    Sevgi Mir

    2013-01-01

    Full Text Available To determine the incidence of renal scarring among patients with primary vesicoureteral reflux (VUR and the possible risk factor(s, we studied 90 children (60 girls and 30 boys with VUR followed in the Pediatric Nephrology Unit at the Ege University Hospital from 1998 to 2003. All the patients were assessed for VUR grade by voiding cystoureterography and for presence of renal scarring by (99 m technetium dimercapto-succinic acid scintigraphy. All infants with VUR were given low-dose prophylactic antibiotics and followed-up until resolution of the reflux. Grade of reflux and number of urinary tract infection (UTI episodes (≥3 were found to be statistically significant risk factors for renal scarring (P 0.05. Similarly, there was no statistically significant difference of frequency of renal scarring among the different age groups (P >0.05. We conclude that recurrences of UTI and VUR severity are significant risk factors for renal scarring in children with VUR. Therefore, identification of VUR at an early age may offer the opportunity to prevent episodes of UTI and possible formation of renal scars that may result in end-stage renal failure.

  16. IT Services Availability during the Annual CERN Closure 2006

    CERN Multimedia

    2006-01-01

    Most of the physics, technical, administrative and communications services provided by the IT Department, including LCG (EGEE) production services, will remain available during the CERN annual closure (although EDH requests will stay queued). No interruptions are scheduled (beyond PABX maintenance work on 3-5 January 2007) but restoration of services in case of failure cannot be guaranteed. Problems which arise should be addressed within about half a day except around Christmas Eve and Christmas Day (24 and 25 December) and New Year's Eve and New Year's Day (31 December and 1 January). Incidents will be documented at http://cern.ch/ssb. Although the backup service will be operational, backups cannot be guaranteed and file restores will not be possible. Damaged tapes in Castor will not be processed. Please note that the Helpdesk will be closed but an operator service will be maintained throughout and can be reached at extension 75011 or by email to computer.operations@cern.ch where urgent problems may be ad...

  17. Mesiodens in primary, mixed and permanent dentitions: a clinical and radiographic study.

    Science.gov (United States)

    Ersin, Nazan Kocatas; Candan, Umit; Alpoz, Ali Riza; Akay, Cemal

    2004-01-01

    The term mesiodens refers to a supernumerary tooth located between the maxillary central incisors. The aim of the study was to investigate the characteristics of mesiodens among children in Turkey. The study population involved 24 children who attended the Department of Pediatric Dentistry, Ege University for dental problems. The characteristics of mesiodens were obtained from clinical and radiographic examinations. Results showed that twenty-four patients had thirty-four mesiodens for an average of 1.42 mesiodens per person. Males were affected approximately 3 times more frequently in comparison with females. Forty-two percent of the patients had bilateral mesiodens. All of the mesiodens were conical in shape and 91% were in the downward position. The age and sex distribution, location, direction, eruption of mesiodens and effects on permanent maxillary incisors were also presented in this study. It could be concluded that, delayed, ectopic or asymmetric eruption of the central incisors should alert the clinician to the possibility of a mesiodens.

  18. Grid and Entrepreneurship Workshop

    CERN Multimedia

    2006-01-01

    The CERN openlab is organising a special workshop about Grid opportunities for entrepreneurship. This one-day event will provide an overview of what is involved in spin-off technology, with a special reference to the context of computing and data Grids. Lectures by experienced entrepreneurs will introduce the key concepts of entrepreneurship and review, in particular, the industrial potential of EGEE (the EU co-funded Enabling Grids for E-sciencE project, led by CERN). Case studies will be given by CEOs of European start-ups already active in the Grid and computing cluster area, and regional experts will provide an overview of efforts in several European regions to stimulate entrepreneurship. This workshop is designed to encourage students and researchers involved or interested in Grid technology to consider the entrepreneurial opportunities that this technology may create in the coming years. This workshop is organized as part of the CERN openlab student programme, which is co-sponsored by CERN, HP, ...

  19. Computing for Finance

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    The finance sector is one of the driving forces for the use of distributed or Grid computing for business purposes. The speakers will review the state-of-the-art of high performance computing in the financial sector, and provide insight into how different types of Grid computing – from local clusters to global networks - are being applied to financial applications. They will also describe the use of software and techniques from physics, such as Monte Carlo simulations, in the financial world. There will be four talks of 20min each. The talk abstracts and speaker bios are listed below. This will be followed by a Q&A panel session with the speakers. From 19:00 onwards there will be a networking cocktail for audience and speakers. This is an EGEE / CERN openlab event organized in collaboration with the regional business network rezonance.ch. A webcast of the event will be made available for subsequent viewing, along with powerpoint material presented by the speakers. Attendance is free and open to all. R...

  20. [Determination of residual glycol ethers in leather and leather products by gas chromatography/mass spectrometry].

    Science.gov (United States)

    Wang, Ghengyun; Zhang, Weiya; Li, Lixia; Shen, Yalei; Lin, Junfeng; Xie, Tangtang; Chu, Naiqing

    2014-08-01

    An effective method was established for the simultaneous determination of residual glycol ethers in leather and leather products by gas chromatography/mass spectrometry. Glycol ethers in leather and leather products were ultrasonically extracted at 45 °C, using ethyl acetate as the extraction solvent. The extracts were purified by solid phase extraction (SPE) columns, and then analyzed by gas chromatography/mass spectrometry in selected ion monitoring mode. The content of each analyte was calibrated by external standard method. The limit of detection of ethylene glycol ethyl ether (EGEE) was 0. 10 mg/kg under the condition of signal to noise (S/N) of 3 and the limits of the other 11 glycol ethers were all less than 0.05 mg/kg. The spiked recoveries varied from 81. 2% to 95. 5% at three different spiked levels with the relative standard deviations (RSDs) ranged from 1.4% to 6. 6%. The proposed method is simple, rapid and accurate, with the limits of detection much less than the requirements of the Regulation Concerning Registration, Evaluation, Authorization and Restriction of Chemicals (REACH) of European Union. It is applicable to the determination of residual glycol ethers in leather and leather products, and provides a reference for the relevant testing standards.

  1. Summary and analysis of the available information for the Ecosystem Approach to Fisheries management in Turkey

    Directory of Open Access Journals (Sweden)

    Adnan Tokaç

    2014-03-01

    Full Text Available This review has been prepared by Ege University, a partner of the CREAM Project, on the basis of data and information relevant to Turkish fisheries. To this end, data belonging to a total of 31 information sources produced from 19 fisheries studies were collected, investigated, and analysed. The data are heterogeneous and were obtained from scientific studies, national and international fisheries projects, regulations, management tools, and information on marine protected areas and no-take zones, all of which may be relevant to the ecosystem approach to Turkish fisheries. Analysis of these data shows that few studies have potential to serve the Ecosystem Approach to Fisheries (EAF management in Turkey. In other words, there is a lot to be done in order to organize current fishing, aquaculture and other costal activities for EAF management, for which transition is targeted in Turkey’s 10th five-year development programme. This review aims to present results of scientific research, decisions taken, applied enforcements, and a summary of presently used technical measures from the EAF perspective for sustainable fisheries. It also puts forward suggestions on strategies needed for transition to targeted EAF management in Turkey.

  2. Vibroacoustics of the piano soundboard: Reduced models, mobility synthesis, and acoustical radiation regime

    CERN Document Server

    Boutillon, Xavier

    2013-01-01

    In string musical instruments, the sound is radiated by the soundboard, subject to the strings excitation. This vibration of this rather complex structure is described here with models which need only a small number of parameters. Predictions of the models are compared with results of experiments that have been presented in Ege et al. [Vibroacoustics of the piano soundboard: (Non)linearity and modal properties in the low- and mid- frequency ranges, Journal of Sound and Vibration 332 (5) (2013) 1288-1305]. The apparent modal density of the soundboard of an upright piano in playing condition, as seen from various points of the structure, exhibits two well-separated regimes, below and above a frequency flim that is determined by the wood characteristics and by the distance between ribs. Above flim, most modes appear to be localised, presumably due to the irregularity of the spacing and height of the ribs. The low-frequency regime is predicted by a model which consists of coupled sub-structures: the two ribbed ar...

  3. Myocardial Inflammation-Are We There Yet?

    Science.gov (United States)

    Greulich, Simon; Ferreira, Vanessa M; Dall'Armellina, Erica; Mahrholdt, Heiko

    Several exogenous or endogenous factors can lead to inflammatory heart disease. Beside infectious myocarditis, other systemic inflammatory disorders such as sarcoidosis, systemic lupus erythematosus (SLE), systemic sclerosis (SSc), Churg-Strauss syndrome, and rheumatoid arthritis can affect the myocardium. Myocardial inflammation may have a major impact on the outcome of these patients, resulting in sudden cardiac death, severe arrhythmias, or end-stage heart failure. The current gold standard for definite confirmation of inflammatory heart disease is endomyocardial biopsy (EMB), but is invasive and suffers low sensitivity and specificity due to sampling errors. Thus, non-invasive methods for detecting the extent and changes over time of the inflammatory myocardial disease are needed. Cardiac magnetic resonance (CMR) is such a non-invasive method. We will describe and discuss different approaches for CMR assessment of inflammatory myocardial disease including early gadolinium enhancement (EGE), T2-weighted imaging, late gadolinium enhancement (LGE), the newer mapping proton relaxation techniques (T1 pre-contrast, T1 post-contrast, T2 mapping), and the hybrid PET/MRI technique.

  4. Cardiac magnetic resonance imaging in myocardial inflammation in autoimmune rheumatic diseases: An appraisal of the diagnostic strengths and limitations of the Lake Louise criteria.

    Science.gov (United States)

    Mavrogeni, Sophie; Schwitter, Juerg; van Rossum, Albert; Nijveldt, Robin; Aletras, Antony; Kolovou, Genovefa; Pohost, Gerald; Lima, Joao

    2017-11-14

    Myocardial inflammation in autoimmune rheumatic diseases (ARDs) is the endpoint of various pathophysiologic processes. The Lake Louise-criteria is the most popular approach for the diagnosis of myocarditis. However, due to the diversity of myocardial inflammation in ARDs, some issues should be acknowledged. Of the three Lake Louise indices, early and late gadolinium enhancement (EGE and LGE respectively) measurements may be affected by co-existing disease processes or be present due to a fibrotic ARD like systemic sclerosis, leaving T2-ratio as the only uniformly robust measurement across ARDs. It thus becomes apparent that the Lake Louise criteria suffer from a number of limitations when ARD patients are assessed based on them. The introduction of T1/T2 mapping allowed the quantification of intramyocardial fibrosis missed by LGE and the detection of myocardial oedema respectively, both commonly found in ARDs. The Lake Louise criteria play an important role in the evaluation of AIMI in ARDs. However, the pathophysiologic background of cardiac involvement in ARDs should always be acknowledged in their evaluation. Even though the inclusion of T1/T2 mapping and ECV may better describe diffuse oedema and fibrosis, further investigation pertaining to their implementation in ARD assessment algorithms through multicenter studies is needed. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  5. European projects: a new wave of success

    CERN Multimedia

    2011-01-01

    Since the beginning of this year, no fewer than six new EU projects at CERN have been launched. These are just a third of the projects selected by the European Commission for funding during the course of 2010, bringing in some 23 M€ over a period of two to five years. This makes last year our most successful yet in securing EU support, and places CERN among the top 50 out of more than 10,000 participants in the EU’s seventh Framework Programme.   The success rate of our proposals has been very good ever since the beginning of FP7 in 2007, particularly for projects coordinated by CERN. There has been a clear evolution of CERN’s involvement in EU projects over the last 10 years. In the early days, we tended to target the Marie Curie actions and the e-Infrastructures Programme. The former help us to fulfil our mission to train young people, while the latter supported the development of the European Grid, mainly through the EGEE projects. Later, the Organization became a...

  6. Clinical investigation of traumatic injuries of permanent incisors in Izmir, Turkey.

    Science.gov (United States)

    Calişkan, M K; Türkün, M

    1995-10-01

    470 injured teeth of 370 patients who consulted the Dental Clinic of Ege University, Izmir, Turkey for examination or treatment between 1981-1993 were evaluated. Information concerning sex, age of patients at the time of injury, cause of trauma, number of injured teeth, type of tooth and type of trauma were recorded. More boys suffered traumatic injuries (64.8%) than girls (35.2%). Patients aged 11-15 years old exhibited the highest number of injuries (34.4%) followed by the 6-10 years old group (24.5%). Most injuries involved one tooth (60%) and maxillary central incisors were the most often affected teeth (66.2%). The leading cause of injury was undefined falls (45.1%). At the initial examination, cases seen after a long posttraumatic period showed more complications than those presented within a short time period. Educational programs about the importance of dental trauma, the benefits of immediate attendance and conservation of avulsed and fractured teeth would be very helpful for patients. Additionally improving the knowledge of the dental practitioner about trauma would be another important point in solving the problem.

  7. Laparoscopic virtual reality simulator and box trainer in gynecology.

    Science.gov (United States)

    Akdemir, Ali; Sendağ, Fatih; Oztekin, Mehmet K

    2014-05-01

    To investigate whether a virtual reality simulator (LapSim) and traditional box trainer are effective tools for the acquisition of basic laparoscopic skills, and whether the LapSim is superior to the box trainer in surgical education. In a study at Ege University School of Medicine, Izmir, Turkey, between September 2008 and March 2013, 40 first- and second-year residents were randomized to train via the LapSim or box trainer for 4 weeks, and 20 senior residents were allocated to a control group. All 3 groups performed laparoscopic bilateral tubal ligation. Video records of each operation were assessed via the general rating scale of the Objective Structured Assessment of Laparoscopic Salpingectomy and by operation time in seconds. Compared with the control group, the LapSim and box trainer groups performed significantly better in total score (Peducation. Training with a virtual reality simulator or box trainer should be considered before actual laparoscopic procedures are carried out. Copyright © 2014 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.

  8. A NEW CONTROL CIRCUIT AND COMPUTER SOFTWARE FOR CONTROLING PHOTOVOLTAIC SYSTEMS

    Directory of Open Access Journals (Sweden)

    Mustafa Berkant SELEK

    2008-02-01

    Full Text Available In this study, a new microcontroller circuit was designed and new computer software was implemented to control power flow currents of renewable energy system, which is established in Solar Energy Institute, Ege University, Bornova, Izmir, Turkey. PIC18F452 microcontroller based electronic circuit was designed to control another electronic circuit that includes power electronic switching components. Readily available standard control circuits are designed for switching single level inverters. In contrary, implemented circuit allows to switch multilevel inverters. In addition, because the efficiency of solar energy panels is considerably low, solar panels should be operated under the maximum power point (MPP. Therefore, MPP algorithm is included in the designed control circuit. Next, the control circuit also includes a serial communication interface based on RS232 standard. Using this interface enables the user to choose all functions available in the control circuit and take status report via computer software. Last, a general purpose command set was designed to establish communication between the computer software and the microcontroller-based control circuit. As a result, it is aimed that this study supply a basis for the researchers who want to develop own control circuits or more visual software.

  9. A Case Report: Subcutaneous Myiasis Caused by Dermatobia Hominis After a Trip to Brazil

    Directory of Open Access Journals (Sweden)

    Fatma Kamer Varıcı Balcı

    2017-12-01

    Full Text Available Myiasis is an invasive diseases caused by larvae of various Dipterian flies. Subcutaneus myiasis cases are commonly observed by Dermatobia hominis larvea. A 26-year-old female patient with a history of travel abroad. Brasil diagnosed with subcutaneous myiasis originating from D. hominis. After spending six months in Amazon forests, Brasil, patient observed two small erythematous papules on right lower quadrant abdomen and delicate and itchy in the sacral region. Two larvae removed from the papules were sent to Ege University Medical Faculty Polyclinic of Infectious Diseases and sent to the parasitology polyclinic for the identification of larval species. After the necessary macroscopic and microscopic examinations, D. hominis was obtained as aresult of myiasis effect. Geographically, natural distribution of D. hominis is South American countries. In this case report we want to introduce the mechanism of egg distribution and take attention to the importance of medical history on myiasis cases. Since it is the first case seen in Turkish patients, it is thought to be presented in terms of revealing the importance of anamnesis in myiasis cases.

  10. Evidence-guided education: patients' outcome data should influence our teaching priorities.

    Science.gov (United States)

    Glick, Thomas H

    2005-02-01

    How should medical educators choose learning objectives and teaching content in clinical education? Given the information chain reaction, coverage of all significant topics in sufficient depth is not possible. Choosing subjects of high priority is essential if education is to have maximum impact on quality of care. These priorities should not derive from tradition and opinion, but should be informed by patient outcomes, the ultimate standard for assessing educational effectiveness. Building upon prior initiatives linking education to practice, the author uses the term "evidence-guided education" to express the process of influencing curricular choices with evidence from health outcomes. Sources of outcome evidence include incident reports, morbidity and mortality conferences, surveillance of quality of care in particular venues, case series, surveys of adverse events and "near-misses," and malpractice claims. Starting with anecdotal occurrences, additional case-finding may establish patterns of poor outcomes, some of which may be preventable. Credible research data on outcomes can inform prioritization for objectives and content at successive institutional levels, which should improve practices and outcomes, completing the loop of feedback, implementation, and improved health. The closer the educational intervention is to practice, the more accountable it becomes. Thus, EGE is more amenable to evaluation at residents' and practitioners' levels and more difficult at the undergraduate level. However, outcome evidence should still inform undergraduate teaching, since this constitutes the platform for future learning. Severe constraints on learning time mandate prioritization of content and suggest the need for the judicious application of outcome evidence in place of mere opinion.

  11. Panic Attack during Elective Gastrointestinal Endoscopy

    Directory of Open Access Journals (Sweden)

    Charalampos Mitsonis

    2011-01-01

    Full Text Available Background. Esophagogastroduodenoscopy (EGD and colonoscopy (CS can evoke anxiety, embarrassment, and discomfort. These concerns can culminate in panic attacks, which may traumatize patients and significantly decrease their compliance to the procedure. The objective of this study was to evaluate the relationship between preendoscopic anxiety and the possibility of a panic attack during an elective gastrointestinal endoscopy (EGE. Methods. The study population comprised of 79 Greek outpatients. The examination was carried out without the use of conscious sedation. Patients' anxiety levels were assessed before the procedure using the Greek version of the Spielberger State-Trait Anxiety Inventory (STAI-Y. Results. Seventy-nine patients were enrolled: 45 EGD and 34 CS. Females had higher state and trait anxiety levels than males (48.14 ± 7.94 versus 44.17 ± 7.43, <0.05; and 43.68 ± 6.95 versus 39.86 ± 7.46, <0.05. Patients who experienced panic attack had significantly higher levels of both trait and state anxiety, compared to those who were panic-free. There was no significant relationship between panic attacks and sex or type of procedure. Conclusions. Patients who experience panic attacks during endoscopic procedures appear to have significantly higher anxiety levels before the procedure. Administering the STAI questionnaire prior to the endoscopy seems to be a useful screening method for vulnerable patients.

  12. Bir tıp fakültesi birinci sınıf öğrencilerinde toplumsal cinsiyet algı düzeyi ve ilişkili faktörlerin değerlendirilmesi

    OpenAIRE

    Varol, Zeynep Sedef; Çiçeklioğlu, Meltem; Taner, Şafak

    2016-01-01

    Amaç: Bu çalışmanın amacı bir tıp fakültesi birinci sınıf öğrencilerinin toplumsal cinsiyet algı düzeyi ve ilişkili faktörleri değerlendirmektir. Gereç ve Yöntem: Kesitsel araştırma şeklinde yürütülen çalışma Ege Üniversitesi Tıp Fakültesi 2013-2014 eğitim yılında birinci sınıfta okuyan 435 öğrenciden 352'sine (%81) ulaşılarak gerçekleştirilmiştir. Veri toplama aracı olarak 24 sorudan ve iki alt skaladan oluşan Cinsiyet Eşitliği Ölçeğinin (CEÖ) Türkçe versiyonu ve sosyo-demografik özell...

  13. Description of a new sepioline species, Sepiola boletzkyi sp. nov. (Cephalopoda: Sepiolidae, from the Aegean Sea

    Directory of Open Access Journals (Sweden)

    Giambattista Bello

    2015-10-01

    Full Text Available A new sepioline species, Sepiola boletzkyi sp. nov. (Cephalopoda: Sepiolidae, is described based on two specimens from the Aegean Sea (eastern Mediterranean. The type specimens are lodged in the Ege University Faculty of Fisheries Museum of Izmir (Turkey. The new species belongs to the Sepiola atlantica group sensu Naef, hence it is compared with the species in this group, namely Sepiola affinis, Sepiola atlantica, Sepiola bursadhaesa, Sepiola intermedia, Sepiola robusta, Sepiola rondeletii, Sepiola steenstrupiana and Sepiola tridens. The male of S. boletzkyi sp. nov. differs from all the others in having the combination of homomorphous ventral arm tips, eight enlarged suckers, subdivided into two groups, in the dorsal row of the distal part of the hectocotylus and a dorsal lobe complementing the copulatory apparatus. In females of S. boletzkyi sp. nov. the bursa copulatrix is large and, unlike all other species in the genus, has a large fungiform process towards the mantle wall. The discovery of S. boletzkyi sp. nov. increases to 12 the number of NE Atlantic-Mediterranean species of Sepiola.

  14. A virtual laboratory for medical image analysis.

    Science.gov (United States)

    Olabarriaga, Sílvia D; Glatard, Tristan; de Boer, Piter T

    2010-07-01

    This paper presents the design, implementation, and usage of a virtual laboratory for medical image analysis. It is fully based on the Dutch grid, which is part of the Enabling Grids for E-sciencE (EGEE) production infrastructure and driven by the gLite middleware. The adopted service-oriented architecture enables decoupling the user-friendly clients running on the user's workstation from the complexity of the grid applications and infrastructure. Data are stored on grid resources and can be browsed/viewed interactively by the user with the Virtual Resource Browser (VBrowser). Data analysis pipelines are described as Scufl workflows and enacted on the grid infrastructure transparently using the MOTEUR workflow management system. VBrowser plug-ins allow for easy experiment monitoring and error detection. Because of the strict compliance to the grid authentication model, all operations are performed on behalf of the user, ensuring basic security and facilitating collaboration across organizations. The system has been operational and in daily use for eight months (December 2008), with six users, leading to the submission of 9000 jobs/month in average and the production of several terabytes of data.

  15. Berberine: metabolic and cardiovascular effects in preclinical and clinical trials

    Directory of Open Access Journals (Sweden)

    Arrigo FG Cicero

    2009-09-01

    Full Text Available Arrigo FG Cicero1, Sibel Ertek21Internal Medicine, Aging and Kidney Diseases Department, Sant’Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy; 2Ufuk University, Medical Faculty, Dr Ridvan Ege Hospital, Department of Endocrinology and Metabolic Diseases, Ankara, TurkeyAbstract: Berberine is a plant alkaloid with numerous biological activities. A large body of preclinical in vitro and in vivo studies support different pharmacological actions of berberine that could be potentially useful in the management of metabolic diseases associated with high cardiovascular disease risk, such as mixed hyperlipidemia, insulin resistance, metabolic syndrome, and type 2 diabetes. Moreover, it seems that berberine also exerts anti-inflammatory and antiproliferative effects that could play a role in the development of atherosclerosis and its clinical consequences. Recently, the metabolic effects of berberine have been demonstrated in humans, opening new perspectives for the use of this molecule in patient therapy. Larger and longer clinical studies need to be carried out to implement the definition of the therapeutic role of berberine in humans.Keywords: berberine, cardiovascular disease, diabetes, cholesterol

  16. Lunar Module Wiring Design Considerations and Failure Modes

    Science.gov (United States)

    Interbartolo, Michael

    2009-01-01

    This slide presentation reviews the considerations for the design of wiring for the Lunar Module. Included are a review of the choice of conductors and insulations, the wire splicing (i.e., crimping, and soldering), the wire connectors, and the fabrication of the wire harnesses. The problems in fabrication include the wires being the wrong length, the damage due to the sharp edges, the requried use of temproary protective covers and inadequate training. The problems in the wire harness installation include damge from sharp eges, work on adjacent harnesses, connector damage, and breaking wires. Engineering suggestions from the Apollo-era in reference to the conductors that are reviewed include: the use of plated conductors, and the use of alloys for stronger wiring. In refernce to insulation, the suggestions from Apollo era include the use of polymer tape-wrap wire insulation due to the light weight, however, other types of modern insulation might be more cost-effective. In reference to wire splices and terminal boards the suggestions from the Apollo Era include the use of crimp splices as superior to solder splices, joining multiple wire to a common point using modular plug-ins might be more reliable, but are heavier than crimp splicing. For connectors, the lessons from the Apollo era indicate that a rear environmental seal that does not require additional potting is preferred, and pins should be crimped or welded to the incoming wires and be removable from the rear of the connector.

  17. Molecular Subtype Distribution and Cyclooxygenase-2 Expression Situation in Inflammatory Breast Cancer

    Directory of Open Access Journals (Sweden)

    Püsem Patır

    2016-08-01

    Full Text Available Objective: Inflammatory breast cancer (IBC is a rare and aggressive form of locally advanced breast cancer. Currently, almost all women with IBC have lymph node involvement and approximately one-third have distant metastases. Therefore, there is still need for understanding of the molecular biology and new therapy alternatives in IBC. The purpose of this study was to determine the potential role of the cyclooxygenase-2 (COX-2 expression pattern in the aggressive and fatal course of IBC and to investigate the possibility of using COX-2 inhibitors as therapy options in the treatment of IBC. Materials and Methods: IBC samples obtained from breast cancer patients treated Between 2000-2009 in Ege University Faculty of Medicine Department of Medical Oncology were retrospectively evaluated. Immunohistochemical analysis was performed by a special breast cancer pathologist and manually assessed using an immunohistochemical scoring for both staining intensity and percentage. Results: In this study, the molecular subtypes identified in IBC patients were: basal (31%, luminal B/human epidermal growth factor receptor 2 (HER2- (22%, luminal B/HER2+ (22%, HER2 (17% and luminal A (8%. COX-2 expression was found to be positive in 92.6% of patients. Conclusion: In this context, it was concluded that the relatively high expression rate of COX-2 could be a reason for poor prognosis and also might lead to the use of COX-2 inhibitors not only as a single agent but also in combination with current chemotherapeutic agents in patients with IBC.

  18. The effect of experience on composite resin shade selection in comparison to a spectrophotometer

    Directory of Open Access Journals (Sweden)

    Duygu Recen

    2016-01-01

    Full Text Available OBJECTIVE: The objective of this study was to compare the shade matching ability of dentists with different experience levels in comparison to a spectrophotometer. MATERIALS AND METHOD: Participants were selected from the volunteer fourth grade students of Faculty of Dentistry, Ege University (n=100. A fifthyear undergraduate student, a research assistant with 2 years of experience and two professors of restorative dentistry with at least 10 years of experience were included in this study as observers. Ishihara color blindness test was applied to all observers before taking shades. After taking the shades with conventional method by using Vita Classical shade guide, the research assistant took the shades again with SpectroShade Micro device. Agreement on shade matches was evaluated by percentage and compared using Wilcoxon test (p0.05 and the correct match rate of the research assistant was superior to the others. Statistically significant differences were found between the fifth grade student’s shade assignments and the research assistant’s assignments as well as the device’s readings (p<0.05. CONCLUSION: Within the limitations of this study, it was concluded that shade matching is a learnable process. In order to do a correct shade match in complicated situations, dentists may refer to spectrophotometric devices.

  19. The High-Tech Face of e-Health

    CERN Document Server

    Shiers, Jamie D

    2014-01-01

    This chapter focuses on the current and potential use of e-Infrastructures in the domain of eHealth. It starts by identifying a small number of specific Use Cases and then addresses how these can be optimized—or possibly revolutionized—by the use of state-of-the-art distributing computing infrastructures (DCIs). Specific topics that are addressed include “long-term” data preservation (for the duration of a patient’s life as well as (far) beyond for collective-oriented studies), federation of heterogeneous data sources, provision of redundant and highly accessible data storage and federated identity management. The work draws heavily on the author’s experience in distributed computing infrastructures to address the challenges of the Large Hadron Collider at CERN, together with participation in generic e-Infrastructure projects, such as the EGEE project services and EGI. It also benefits from experience in hadron-therapy oriented projects with which CERN has synergies both as an accelerator laborato...

  20. Use Of New Media In The Local Press: Comparative Analysis Of Local Newspapers Websites In İzmir, Adana and Bursa

    Directory of Open Access Journals (Sweden)

    Berrin Kalsin

    2016-01-01

    Full Text Available Local press is defined as a press that serves to introduce and train the public and to provide the public opinion.  Local press gives information about the cases happen around the region that it is published and it forms public opinion about the problems of that region.  New communication technologies havehave an important role in the forming and enhancing the news contents in the media. Changeovers have occurred in the production,  process and distributiondistribution of the news by developing the new media. On the other hand,  Internet journalism used by many press institutions is occurredoccurred as a new concept in mass communication.  National and local newspapers do not remain insensitive to this new mass communication and it attempts the Internet journalism. Firstly,  pressed newspaper had been turned into Web sites as similar but later new application about the transferring the news to the reader have occurred when we look at this application about the transferring of the pressed newspaper to the Internet environment.  In this study, the Internet websites if Adanaher from Adana,  Olay from Bursa and Ege'nin Sesi from Izmir have been compared with each other.  The form, content and interaction of these three newspapers have been discussed and the usage of social media and importance given to the local news have been analyzed.

  1. Rapid fingerprinting and classification of extra virgin olive oil by microjet sampling and extractive electrospray ionization mass spectrometry.

    Science.gov (United States)

    Law, Wai Siang; Chen, Huan Wen; Balabin, Roman; Berchtold, Christian; Meier, Lukas; Zenobi, Renato

    2010-04-01

    Microjet sampling in combination with extractive electrospray ionization (EESI) mass spectrometry (MS) was applied to the rapid characterization and classification of extra virgin olive oil (EVOO) without any sample pretreatment. When modifying the composition of the primary ESI spray solvent, mass spectra of an identical EVOO sample showed differences. This demonstrates the capability of this technique to extract molecules with varying polarities, hence generating rich molecular information of the EVOO. Moreover, with the aid of microjet sampling, compounds of different volatilities (e.g.E-2-hexenal, trans-trans-2,4-heptadienal, tyrosol and caffeic acid) could be sampled simultaneously. EVOO data was also compared with that of other edible oils. Principal Component Analysis (PCA) was performed to discriminate EVOO and EVOO adulterated with edible oils. Microjet sampling EESI-MS was found to be a simple, rapid (less than 2 min analysis time per sample) and powerful method to obtain MS fingerprints of EVOO without requiring any complicated sample pretreatment steps.

  2. Cumulative clinical experience from a decade of use: imatinib as first-line treatment of chronic myeloid leukemia

    Directory of Open Access Journals (Sweden)

    Baran Y

    2012-11-01

    Full Text Available Yusuf Baran,1 Guray Saydam21Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Turkey; 2Department of Hematology, School of Medicine, Ege University, Izmir, TurkeyAbstract: Chronic myeloid leukemia (CML is a malignant disease that originates in the bone marrow and is designated by the presence of the Philadelphia (Ph+ chromosome, a translocation between chromosomes 9 and 22. Targeted therapy against CML commenced with the development of small-molecule tyrosine kinase inhibitors (TKIs exerting their effect against the oncogenic breakpoint cluster region (BCR-ABL fusion protein. Imatinib emerged as the first successful example of a TKI used for the treatment of chronic-phase CML patients and resulted in significant improvements in response rate and overall survival compared with previous treatments. However, a significant portion of patients failed to respond to the therapy and developed resistance against imatinib. Second-generation TKIs nilotinib and dasatinib were to have higher efficiency in clinical trials in imatinib- resistant or intolerant CML patients compared with imatinib. Identification of novel strategies such as dose escalation, drug combination therapy, and use of novel BCR-ABL inhibitors may eventually overcome resistance against BCR-ABL TKIs. This article reviews the history of CML, including the treatment strategies used prediscovery of TKIs and the preclinical and clinical data obtained after the use of imatinib, and the second-generation TKIs developed for the treatment of CML.Keywords: drug resistance, tyrosine kinase inhibitors, chronic myeloid leukemia, imatinib, BCR/ABL

  3. ETICS: the international software engineering service for the grid

    Science.gov (United States)

    Meglio, A. D.; Bégin, M.-E.; Couvares, P.; Ronchieri, E.; Takacs, E.

    2008-07-01

    The ETICS system is a distributed software configuration, build and test system designed to fulfil the needs of improving the quality, reliability and interoperability of distributed software in general and grid software in particular. The ETICS project is a consortium of five partners (CERN, INFN, Engineering Ingegneria Informatica, 4D Soft and the University of Wisconsin-Madison). The ETICS service consists of a build and test job execution system based on the Metronome software and an integrated set of web services and software engineering tools to design, maintain and control build and test scenarios. The ETICS system allows taking into account complex dependencies among applications and middleware components and provides a rich environment to perform static and dynamic analysis of the software and execute deployment, system and interoperability tests. This paper gives an overview of the system architecture and functionality set and then describes how the EC-funded EGEE, DILIGENT and OMII-Europe projects are using the software engineering services to build, validate and distribute their software. Finally a number of significant use and test cases will be described to show how ETICS can be used in particular to perform interoperability tests of grid middleware using the grid itself.

  4. Update on peripheral ulcerative keratitis

    Directory of Open Access Journals (Sweden)

    Yagci A

    2012-05-01

    Full Text Available Ayse YagciEge University, School of Medicine, Department of Ophthalmology, Izmir, TurkeyAbstract: Ulcerative inflammation of the cornea occurs in the perilimbal cornea, and is associated with autoimmune collagen vascular and arthritic diseases. Rheumatoid arthritis is the most frequent underlying disease. The tendency for peripheral location is due to the distinct morphologic and immunologic characteristics of the limbal conjunctiva, which provides access for circulating immune complexes to the peripheral cornea via the capillary network. Deposition of immune complexes in the terminal ends of limbal vessels initiates immune-mediated vasculitis, and causes inflammatory cell and protein leakage due to vessel wall damage. Development of peripheral ulcerative keratitis associated with systemic disease may represent worsening of a potentially life-threatening disease. Accompanying scleritis, particularly the necrotizing form, is usually observed in severe cases, which may result in corneal perforation and loss of vision. Although first-line treatment with systemic corticosteroids is indicated for acute phases, immunosuppressive and cytotoxic agents are required for treatment of peripheral ulcerative keratitis associated with multisystem disorders. Recently, infliximab, a chimeric antibody against proinflammatory cytokine tumor necrosis factor-alpha, was reported to be effective in cases refractory to conventional immunomodulatory therapy. The potential side effects of these therapies require close follow-up and regular laboratory surveillance.Keywords: autoimmune disease, peripheral ulcerative keratitis, treatment, tumor necrosis factor-alpha

  5. Differences in quality of life between infertile women and men in Turkey.

    Science.gov (United States)

    Bolsoy, Nursen; Taspinar, Ayten; Kavlak, Oya; Sirin, Ahsen

    2010-01-01

    To examine potential differences in quality of life between infertile women and men. A descriptive, cross-sectional design. A questionnaire was used to collect individuals' sociodemographic data; the World Health Organization Quality of Life-BREF (WHOQOL-BREF) tool was used to collect information about quality of life. The research sample comprised 248 infertile individuals (141 women and 107 men) admitted to the clinic for the first time for diagnosis and treatment between January 1 and June 30, 2007, and who voluntarily agreed to participate. The research was conducted at the Ege University Family Planning and Infertility Research and Training Center Infertility Clinic in Izmir, Turkey. Physical health, psychological health, and social relations domain score means did not show significant differences between infertile women and infertile men (p>.05). However, score means for the environment domain were significantly higher (pwomen than for infertile men. Unemployed infertile men had significantly lower score means in the physical health and social relation domains (pquality of life domain scores for infertile women or infertile men (p>.05). In the environmental domain, the quality of life of infertile women was greater than that of infertile men. Variables affecting quality of life of infertile individuals were seen to affect women and men in similar ways. Nurses and health care professionals caring for infertile individuals should be aware of the factors that affect quality of life and should plan to meet their care needs accordingly.

  6. [The prevalance of Enterobius vermicularis in primary school which have different socioecomic level in Ankara].

    Science.gov (United States)

    Keskin, Nevin; Ay Bektaş, Ayla

    2014-01-01

    In this study, the prevalence of E. vermicularis and its relation with socioeconomic level, age, race, gender, mother's and father's educational level, income status, and housing type were investigated among 1729 students who were between ages 6-12 at 8 different elementary schools (Eryaman Türkkent, Tahsin Şahinkaya, Şahin, Beytepe, Azmi Ertuğrul, Ege, Semiha İsen, Samime Talat Primary School) in Kazan, Etimesgut, Çankaya, Pursaklar, Mamak, and Sincan in Ankara. A questionnaire form and cellophane-taped slides with locked bags were provided for students between November 2010 and May 2011. In total, 874 (50.5%) of students were female and 855 (49.5%) of them were male. According to the questionnaire, 197 (11.4%) of students had low, 986 (57.1%) moderate, and 545 (31.5%) high income levels. Also, 148 students out of 1729 were found to be infected with E. vermicularis, and the prevalence of Enterobius vermicularis was found 86%; 81% (9.5%) of the infected were male and 67 (7.7%) was female. As the result of study, a significant difference was found between the presence of E. vermicularis and socio-demographic properties. However, there was no significant difference between presence of E. vermicularis and gender. These results show that the importance of socio-demographic properties on the presence of E. vermicularis.

  7. Optimised access to user analysis data using the gLite DPM

    Science.gov (United States)

    Skipsey, Sam; Cowan, Greig; Kenyon, Mike; Purdie, Stuart; Stewart, Graeme

    2010-04-01

    The ScotGrid distributed Tier-2 now provides more that 4MSI2K and 500TB for LHC computing, which is spread across three sites at Durham, Edinburgh and Glasgow. Tier-2 sites have a dual role to play in the computing models of the LHC VOs. Firstly, their CPU resources are used for the generation of Monte Carlo event data. Secondly, the end user analysis data is distributed across the grid to the site's storage system and held on disk ready for processing by physicists' analysis jobs. In this paper we show how we have designed the ScotGrid storage and data management resources in order to optimise access by physicists to LHC data. Within ScotGrid, all sites use the gLite DPM storage manager middleware. Using the EGEE grid to submit real ATLAS analysis code to process VO data stored on the ScotGrid sites, we present an analysis of the performance of the architecture at one site, and procedures that may be undertaken to improve such. The results will be presented from the point of view of the end user (in terms of number of events processed/second) and from the point of view of the site, which wishes to minimise load and the impact that analysis activity has on other users of the system.

  8. Optimising LAN access to grid enabled storage elements

    Science.gov (United States)

    Stewart, G. A.; Cowan, G. A.; Dunne, B.; Elwell, A.; Millar, A. P.

    2008-07-01

    When operational, the Large Hadron Collider experiments at CERN will collect tens of petabytes of physics data per year. The worldwide LHC computing grid (WLCG) will distribute this data to over two hundred Tier-1 and Tier-2 computing centres, enabling particle physicists around the globe to access the data for analysis. Although different middleware solutions exist for effective management of storage systems at collaborating institutes, the patterns of access envisaged for Tier-2s fall into two distinct categories. The first involves bulk transfer of data between different Grid storage elements using protocols such as GridFTP. This data movement will principally involve writing ESD and AOD files into Tier-2 storage. Secondly, once datasets are stored at a Tier-2, physics analysis jobs will read the data from the local SE. Such jobs require a POSIX-like interface to the storage so that individual physics events can be extracted. In this paper we consider the performance of POSIX-like access to files held in Disk Pool Manager (DPM) storage elements, a popular lightweight SRM storage manager from EGEE.

  9. Scalability and interoperability within glideinWMS

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D.; /Wisconsin U., Madison; Sfiligoi, I.; /Fermilab; Padhi, S.; /UC, San Diego; Frey, J.; /Wisconsin U., Madison; Tannenbaum, T.; /Wisconsin U., Madison

    2010-01-01

    Physicists have access to thousands of CPUs in grid federations such as OSG and EGEE. With the start-up of the LHC, it is essential for individuals or groups of users to wrap together available resources from multiple sites across multiple grids under a higher user-controlled layer in order to provide a homogeneous pool of available resources. One such system is glideinWMS, which is based on the Condor batch system. A general discussion of glideinWMS can be found elsewhere. Here, we focus on recent advances in extending its reach: scalability and integration of heterogeneous compute elements. We demonstrate that the new developments exceed the design goal of over 10,000 simultaneous running jobs under a single Condor schedd, using strong security protocols across global networks, and sustaining a steady-state job completion rate of a few Hz. We also show interoperability across heterogeneous computing elements achieved using client-side methods. We discuss this technique and the challenges in direct access to NorduGrid and CREAM compute elements, in addition to Globus based systems.

  10. ArchaeoGRID, the Archaeology on the e-Infrastructures

    Energy Technology Data Exchange (ETDEWEB)

    Pelfer, G.; Cechini, R.; Pelfer, P. G.; Politi, A.

    2007-07-01

    It is well known that in archaeology large use is done of digital technologies and computer applications for data acquisition, storage, analysis and visualization. The approach of modern archaeology to the study of the evolution of ancient human societies is based on the acquisition and analysis of many types of data. The amount of information coming from the archaeology and the other connected sciences and human ties that need to be stored and made available for analysis are increasing at a very large extent. Such data must, however, be analyzed if they are to become valuable information and knowledge. The data analysis use advanced methods developed in mathematics, informatics, physics, geology, biology, ecology, anthropology and in other natural and human sciences. The inevitable result of this is an exponential increase of the amount and complexity of information that must be acquired, transferred, stored, processed and analyzed. From another, side natural disasters, wars and terrorism created enormous damages to the archaeological heritage and in many case destroyed definitively all information about ancient civilizations. It is urgent a long term project for acquiring, storing and preserving at least the archaeological information. The paper presents the EGEE- II ArchaeoGRID project that, using GRID technologies developed at CERN and in other laboratories, is developing a grid able to fit the very challenging requests of contemporary archaeology. (Author)

  11. Redox-Active N-Heterocyclic Germylenes and Stannylenes with a Ferrocene-1,1'-diyl Backbone.

    Science.gov (United States)

    Oetzel, Jan; Weyer, Nadine; Bruhn, Clemens; Leibold, Michael; Gerke, Birgit; Pöttgen, Rainer; Maier, Markus; Winter, Rainer F; Holthausen, Max C; Siemeling, Ulrich

    2017-01-23

    We describe ferrocene-based N-heterocyclic germylenes and stannylenes of the type [Fe{(η5 -C5 H4 )NR}2 E:] (1 RE; E=Ge, Sn; R=neopentyl (Np), mesityl (Mes), trimethylsilyl (TMS)), which constitute the first examples of redox-functionalised N-heterocyclic tetrylenes (NHTs). These compounds are thermally stable and were structurally characterised by means of X-ray diffraction studies, except for the neopentyl-substituted stannylene 1 NpSn, the decomposition of which afforded the aminoiminoferrocene [fc(NHCH2 tBu)(N=CHtBu)] (2) and the spiro tin(IV) compound (1 Np)2 Sn (3). DFT calculations show that the HOMO of the NHTs of our study is localised on the ferrocenylene backbone. A one-electron oxidation process affords ions of the type 1 RE+. . In contrast to the NHC system 1 RC, the localised ferrocenium-type nature of the oxidised form does not compromise the fundamental tetrylene character of 1 RE+. . © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Distributed Data Analysis in ATLAS

    CERN Document Server

    Nilsson, P

    2009-01-01

    Data analysis using grid resources is one of the fundamental challenges to be addressed before the start of LHC data taking. The ATLAS detector will produce petabytes of data per year, and roughly one thousand users will need to run physics analyses on this data. Appropriate user interfaces and helper applications have been made available to ensure that the grid resources can be used without requiring expertise in grid technology. These tools enlarge the number of grid users from a few production administrators to potentially all participating physicists. ATLAS makes use of three grid infrastructures for the distributed analysis: the EGEE sites, the Open Science Grid, and NorduGrid. These grids are managed by the gLite workload management system, the PanDA workload management system, and ARC middleware; many sites can be accessed via both the gLite WMS and PanDA. Users can choose between two front-end tools to access the distributed resources. Ganga is a tool co-developed with LHCb to provide a common interfa...

  13. Distributed Data Analysis in ATLAS

    CERN Document Server

    Nilsson, P; The ATLAS collaboration

    2012-01-01

    Data analysis using grid resources is one of the fundamental challenges to be addressed before the start of LHC data taking. The ATLAS detector will produce petabytes of data per year, and roughly one thousand users will need to run physics analyses on this data. Appropriate user interfaces and helper applications have been made available to ensure that the grid resources can be used without requiring expertise in grid technology. These tools enlarge the number of grid users from a few production administrators to potentially all participating physicists. ATLAS makes use of three grid infrastructures for the distributed analysis: the EGEE sites, the Open Science Grid, and NorduGrid. These grids are managed by the gLite workload management system, the PanDA workload management system, and ARC middleware; many sites can be accessed via both the gLite WMS and PanDA. Users can choose between two front-end tools to access the distributed resources. Ganga is a tool co-developed with LHCb to provide a common interfa...

  14. Achieving Resiliency in Production Worldwide Grid Services for the Large Hadron Collider at CERN

    CERN Document Server

    Shiers, J

    2007-01-01

    The world’s coolest machine – also the largest scientific instrument to date – will enter production in 2008. Operating at a temperature below 2oK, the Large Hadron Collider (LHC) at CERN will generate massive amounts of data – some 15PB per year – that will require significant computational and storage resources. A worldwide production Grid, the Worldwide LHC Computing Grid (WLCG) [1] has been setup, building on the infrastructures of two main Grids – the Open Science Grid (OSG) in the US [2] and the Enabling Grids for E-SciencE in Europe (EGEE) [3] and elsewhere. This is a highly complex system with many components but which must provide a robust and resilient service. This paper describes the state of the Grid in terms of resiliency and is based on a workshop on WLCG Service Reliability held at CERN in November 2007. The goals of the workshop were to discuss and agree the primary techniques for designing, building, deploying and operating robust and resilient services. Concret...

  15. Use of glide-ins in CMS for production and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D [University of Wisconsin-Madison, Madison, WI (United States); Gutsche, O; Holzman, B; Sfiligoi, I; Vaandering, E [Fermilab, Batavia, IL (United States); Hahn, K [Massachusetts Institute of Technology, Cambridge, MA (United States); Padhi, S; Pi, H; Wuerthwein, F [University of California, San Diego, La Jolla, CA (United States); Spiga, D, E-mail: sanjay.padhi@cern.c [CERN, CH-1211 Geneva (Switzerland)

    2010-04-01

    With the evolution of various grid federations, the Condor glide-ins represent a key feature in providing a homogeneous pool of resources using late-binding technology. The CMS collaboration uses the glide-in based Workload Management System, glideinWMS, for production (ProdAgent) and distributed analysis (CRAB) of the data. The Condor glide-in daemons traverse to the worker nodes, submitted via Condor-G. Once activated, they preserve the Master-Worker relationships, with the worker first validating the execution environment on the worker node before pulling the jobs sequentially until the expiry of their lifetimes. The combination of late-binding and validation significantly reduces the overall failure rate visible to CMS physicists. We discuss the extensive use of the glideinWMS since the computing challenge, CCRC-08, in order to prepare for the forthcoming LHC data-taking period. The key features essential to the success of large-scale production and analysis on CMS resources across major grid federations, including EGEE, OSG and NorduGrid are outlined. Use of glide-ins via the CRAB server mechanism and ProdAgent, as well as first hand experience of using the next generation CREAM computing element within the CMS framework is discussed.

  16. Use of glide-ins in CMS for production and analysis

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, D.; /Wisconsin U., Madison; Gutsche, O.; /Fermilab; Hahn, K.; /MIT; Holzman, B.; /Fermilab; Padhi, S.; /UC, San Diego; Pi, H.; /UC, San Diego; Spiga, D.; /CERN; Sfiligoi, I.; /Fermilab; Vaandering, E.; /Fermilab; Wurthwein, F.; /UC, San Diego

    2010-01-01

    With the evolution of various grid federations, the Condor glide-ins represent a key feature in providing a homogeneous pool of resources using late-binding technology. The CMS collaboration uses the glide-in based Workload Management System, glideinWMS, for production (ProdAgent) and distributed analysis (CRAB) of the data. The Condor glide-in daemons traverse to the worker nodes, submitted via Condor-G. Once activated, they preserve the Master-Worker relationships, with the worker first validating the execution environment on the worker node before pulling the jobs sequentially until the expiry of their lifetimes. The combination of late-binding and validation significantly reduces the overall failure rate visible to CMS physicists. We discuss the extensive use of the glideinWMS since the computing challenge, CCRC-08, in order to prepare for the forthcoming LHC data-taking period. The key features essential to the success of large-scale production and analysis on CMS resources across major grid federations, including EGEE, OSG and NorduGrid are outlined. Use of glide-ins via the CRAB server mechanism and ProdAgent, as well as first hand experience of using the next generation CREAM computing element within the CMS framework is discussed.

  17. Avaliação da medida do comprimento do colo e da ausência do eco glandular endocervical para predição do parto pré-termo Evaluation of risk for preterm delivery by measurement of uterine cervix and cervical gland area

    Directory of Open Access Journals (Sweden)

    Claudio Rodrigues Pires

    2004-04-01

    Full Text Available OBJETIVO: verificar a prevalência do sinal eco glandular endocervical (EGE e o comprimento cervical menor ou igual a 20 mm em gestantes entre a 21ª e a 24ª semana e comparar estes sinais ecográficos como fatores indicadores de parto pré-termo espontâneo. MÉTODOS: estudo prospectivo transversal no qual foram incluídas 361 gestantes da população geral, para realização de exame ultra-sonografico em idade gestacional entre a 21ª a 24ª semana. Os critérios de exclusão do estudo foram malformações müllerianas, gestações múltiplas, malformações fetais, óbito fetal, alterações da quantidade de líquido amniótico, placenta com inserção segmentar, antecedentes de cirurgia no colo uterino (conização, amputação, cerclagem e procedimentos cirúrgicos durante a gestação. Após a realização do exame ultra-sonográfico obstétrico morfológico efetuado por via abdominal, seguiu-se o exame ecográfico por via vaginal para observação de uma faixa hipoecóica ou hiperecóica adjacente ao canal endocervical correpondente às glândulas do epitélio endocervical (EGE e mensuração do comprimento cervical. As variáveis qualitativas são representadas por freqüência absoluta e relativa, ao passo que as variáveis quantitativas, por média, desvio-padrão, mediana e valores mínimo e máximo. A associação entre as variáveis qualitativas foi avaliada pelo teste c² ou teste exato de Fisher. Para cada variável estudada, foi calculado o risco relativo seguido do intervalo com 95% de confiança. A técnica de análise de regressão logística univariada foi utilizada para verificar, entre as variáveis estudadas, quais foram indicativas de parto pré-termo espontâneo. O nível de significância adotado foi de 95% (alfa = 5% e descritivos (p iguais ou inferiores a 0,05 foram considerados significantes. RESULTADOS: a incidência do parto pré-termo espontâneo foi de 5,0%. O comprimento do colo uterino revelou-se igual ou

  18. Reduced reward-related probability learning in schizophrenia patients

    Directory of Open Access Journals (Sweden)

    Yılmaz A

    2012-01-01

    Full Text Available Alpaslan Yilmaz1,2, Fatma Simsek2, Ali Saffet Gonul2,31Department of Sport and Health, Physical Education and Sports College, Erciyes University, Kayseri, Turkey; 2Department of Psychiatry, SoCAT Lab, Ege University School of Medicine, Bornova, Izmir, Turkey; 3Department of Psychiatry and Behavioral Sciences, Mercer University School of Medicine, Macon, GA, USAAbstract: Although it is known that individuals with schizophrenia demonstrate marked impairment in reinforcement learning, the details of this impairment are not known. The aim of this study was to test the hypothesis that reward-related probability learning is altered in schizophrenia patients. Twenty-five clinically stable schizophrenia patients and 25 age- and gender-matched controls participated in the study. A simple gambling paradigm was used in which five different cues were associated with different reward probabilities (50%, 67%, and 100%. Participants were asked to make their best guess about the reward probability of each cue. Compared with controls, patients had significant impairment in learning contingencies on the basis of reward-related feedback. The correlation analyses revealed that the impairment of patients partially correlated with the severity of negative symptoms as measured on the Positive and Negative Syndrome Scale but that it was not related to antipsychotic dose. In conclusion, the present study showed that the schizophrenia patients had impaired reward-based learning and that this was independent from their medication status.Keywords: reinforcement learning, reward, punishment, motivation

  19. Experience with the gLite Workload Management System in ATLAS Monte Carlo production on LCG

    CERN Document Server

    Campana, S; Sciabá, A; CERN. Geneva. IT Department

    2008-01-01

    The ATLAS experiment has been running continuous simulated events production since more than two years. A considerable fraction of the jobs is daily submitted and handled via the gLite Workload Management System, which overcomes several limitationsof the previous LCG Resource Broker. The gLite WMS has been tested very intensively for the LHC experiments use cases for more than six months, both in terms of performance and reliability. The tests were carried out by the LCG Experiment Integration Support team (in close contact with the experiments) together with the EGEE integration and certification team and the gLite middleware developers. A pragmatic iterative and interactive approach allowed a very quick rollout of fixes and their rapid deployment, together with new functionalities, for the ATLAS production activities. The same approach is being adopted for other middleware components like the gLite and CREAM Computing Elements. In this contribution we will summarize the learning from the gLite WMS testing a...

  20. Facing Two Rapidly Spreading Internet Worms

    CERN Multimedia

    IT Department

    2009-01-01

    The Internet is currently facing a growing number of computer infections due to two rapidly spreading worms. The "Conficker" and "Downadup" worms have infected an estimated 1.1 million PCs in a 24-hour period, bringing the total number of infected computers to 3.5 million [1]. Via a single USB stick, these worms were also responsible for the infection of about 40 laptops at the last EGEE conference in Istanbul. In order to reduce the impact of these worms on CERN Windows computers, the Computer Security Team has suggested several preventive measures described here. Disabling the Windows AutoRun and AutoPlay Features The Computer Security Team and the IT/IS group have decided to disable the "AutoRun" and "AutoPlay" functionality on all centrally-managed Windows computers at CERN. When inserting CDs, DVDs or USB sticks into a PC, "AutoRun" and "AutoPlay" are responsible for automatically playing music or films stored on these media, or ...

  1. Ortaöğretim Öğrencilerinin Fizik Problemlerini Çözmeye Yönelik Tutumlarının İncelenmesi/ Examining Secondary School Students' In Their Attitudes Towards Solving Problems Of Physics

    OpenAIRE

    Aktamış, Hilal; Çalışkan, Serap; Aktamış, İbrahim

    2013-01-01

    Bu araştırmada, öğrencilerin fizikteki problem çözme becerilerine yönelik tutumlarının 4 yıllık ortaöğretim hayatları boyunca nasıl bir değişim ve gelişim gösterdiğinin belirlenmesi amaçlanmıştır. Betimsel türde ilişkisel tarama modeli ile gerçekleştirilen araştırmanın katılımcılarını Ege bölgesinin bir ilinde ortaöğretim kurumlarında 2011-2012 güz döneminde öğrenim gören ortaöğretim 9, 10, 11 ve 12. sınıf öğrencileri oluşturmaktadır. Öğrencilerin fizik problemlerini çözmeye yönelik tutumları...

  2. Analysis gets on the starting Grid

    CERN Multimedia

    Roger Jones

    It is vital for ATLAS to have a functioning distributed analysis system to analyse its data. There are three major Grid deployments in ATLAS (Enabling Grids for E-sciencE, EGEE; the US Open Science Grid, OSG; and the Nordic DataGrid Facility, NGDF), and our data and jobs need to work across all of them, as well as on local machines and batch systems. Users must also be able to locate the data they want and register new small datasets so they can be used later. ATLAS has a suite of products to meet these needs, and a series of Distributed Analysis tutorials are training an increasing number of brave early adopters to use the system. Real users are vital to make sure that the tools are fit for their purpose and to refine our computing model. One such tutorial happened on the 1st and 2nd February at the National eScience Centre in Edinburgh, UK, sponsored by the GridPP Collaboration. The first day introduced an international set of tutees to the basic tools for Grid-based distributed analysis. The architecture...

  3. Effect of placenta previa on fetal growth restriction and stillbirth.

    Science.gov (United States)

    Yeniel, A Ozgur; Ergenoglu, A Mete; Itil, Ismail Mete; Askar, Niyazi; Meseri, Reci

    2012-08-01

    To examine the association between placenta previa and adverse perinatal outcomes such as low birth weight, preterm delivery, stillbirth and fetal growth restriction (FGR). This retrospective cohort study includes 12,034 delivered pregnant women who were recruited for the study between 2004 and 2010 in Ege University Hospital. Data were collected by browsing the clinic's archives. The association between placenta previa and adverse perinatal outcomes was determined via Chi-square tests and Student's t test. Logistic regression analysis was used to adjust for confounding factors in evaluating the association between placenta previa and the adverse perinatal outcomes. There was no significant relationship between placenta previa and FGR or stillbirth. Low birth weight and preterm delivery were significantly higher in the placenta previa group. According to logistic regression analysis, low birth weight was associated with an OR of 3.01 (95 % CI 2.05-4.52) and preterm delivery was associated with an OR of 8.14 (95 % CI 5.60-11.83); while, placenta previa did not affect FGR and stillbirth significantly. Although there is no consensus on the association between placenta previa and FGR in previous studies, we suggest that placenta previa is not a reason for placental insufficiency. Management of placenta previa especially depends on maternal hemodynamic parameters such as heavy hemorrhage and hypotensive shock rather than fetal well-being protocols based on serial growth ultrasound and fetal Doppler investigation.

  4. How frequent are overactive bladder symptoms in women with urodynamic verification of an overactive bladder?

    Science.gov (United States)

    Yeniel, Ahmet Özgür; Ergenoğlu, Mete Ahmet; Meseri, Reci; Aşkar, Niyazi; Itil, Ismail Mete

    2012-01-01

    To determine the relationship between overactive bladder symptoms and urodynamic verification of overactive bladder. Between June 2011 and November 2011, 159 patients underwent urodynamics (UDS) at our urogynecology unit in the Ege University Hospital. Of these, 95 patients who complained of urgency, did not have any overt neurological diseases, bladder outlet obstruction and did not take any medication affecting the lower urinary tract function were evaluated. SPSS (ver. 15.0) was used to evaluate the data and the chi-square test and t test for independent samples were used for analysis. The mean age was found to be 54.5±12. Frequency was the most frequent symptom in women with overactive bladder (OAB) (82.1%), nocturia (57.8%) and (57.8%) urgency urinary incontinence followed in frequency. Detrusor over activity incidence was found to be 38.9%. There was no significant relationship between the presence of detrusor over activity (DOA) and OAB symptoms. Leak at urodynamics was found in 46.3% and there is no significant association with detrusor overactivity. Total bladder capacity was found to be significantly lower in women who had DOA (p=0.000). It appears that overactive bladder symptoms do not predict detrusor over activity. Urodynamic investigation is not mandatory in the initial management of women with only OAB symptoms.

  5. FARSİ ŞAİRLERİN GÖZÜNDEN, SELÇUKLU SULTANLARI / Seljuk Sultans as Reflected through the eyes of the Persian Poets

    OpenAIRE

    EĞİLMEZ, Savaş

    2015-01-01

    ÖZİslam sonrası Türk tarihinde, ilk kez bü-yük bir devlet kuran Selçuklular olmuştur. Sınırları doğuda Sirderya, batıda Ege ve Marmara Denizleri, kuzeyde Kafkaslar, gü-neyde Mısır’a kadar uzanmış olan Büyük Selçuklu İmparatorluğu, sanatsal anlamda da oldukça gelişmiştir. Çağının en güçlü devleti olması itibarıyla diğer sanat erbaplarıyla beraber şairler de Selçuklu saraylarını tercih ediyorlardı.Biz de bu çalışmada, farsi (İran kökenli) şairlerin gözünden Selçuklu Sultanlarını ve devrin yaşan...

  6. Discovery Mondays: 'The Grid: a universal computer'

    CERN Document Server

    2006-01-01

    How can one store and analyse the 15 million billion pieces of data that the LHC will produce each year with a computer that isn't the size of a sky-scraper? The IT experts have found the answer: the Grid, which will harness the power of tens of thousands of computers in the world by putting them together on one network and making them work like a single computer achieving a power that has not yet been matched. The Grid, inspired from the Web, already exists - in fact, several of them exist in the field of science. The European EGEE project, led by CERN, contributes not only to the study of particle physics but to medical research as well, notably in the study of malaria and avian flu. The next Discovery Monday invites you to explore this futuristic computing technology. The 'Grid Masters' of CERN have prepared lively animations to help you understand how the Grid works. Children can practice saving the planet on the Grid video game. You will also discover other applications such as UNOSAT, a United Nations...

  7. Does Perception of Corporate Culture Change in Time? An Empirical Research

    Directory of Open Access Journals (Sweden)

    Nahit Erdem KÖKER

    2013-03-01

    Full Text Available Fundamental values and belief systems in a corporation show themselves as; norms, behaviours, symbols and compose the corporate culture. When corporate culture is undertaken in terms of business management, it is seen that corporations in different fields have studies directed to culture. In studies of education science and studies that cover educational orporations, corporate culture is named as school culture. Due to the reason that schools are educational corporations, they are a subject to studies of corporate culture. Studies directed to school culture cover the subjects such as; components of school culture, its’ dimensions, structural characteristics, importance of leadership, ect. This study is directed to displaying the changes in the perceptions about school culture of Ege University Faculty of Communication students along their studentship, which is a cultural component and a sub-culture of school culture. With this purpose, data have been collected from students for four years with the same question form. These students were in 1st grade during 2009-2010 academical year. While students are in their 1st, 2nd, 3rd and 4th years, it was foreseen that there were going to be meaningful changes in their perceptions about the dimensions of corporate culture. And the direction of change in their perceptions of faculty culture has been detected in their last year.

  8. Nuclear Fission Reactor Safety Research in FP7 and future perspectives

    CERN Document Server

    Garbil, Roger

    2014-01-01

    The European Union (ЕU) has defined in the Europe 2020 strategy and 2050 Energy Roadmap its long-term vision for establishing a secure, sustainable and competitive energy system and setting up legally binding targets by 2020 for reducing greenhouse emissions, by increasing energy efficiency and the share of renewable energy sources while including a significant share from nuclear fission. Nuclear energy can enable the further reduction in harmful emissions and can contribute to the EU’s competitive energy system, security of supply and independence from fossil fuels. Nuclear fission is a valuable option for those 14 EU countries that promote its use as part of their national energy mix. The European Group on Ethics in Science and New Technologies (EGE) adopted its Opinion No.27 ‘An ethical framework for assessing research, production and use of energy’ and proposed an integrated ethics approach for the research, production and use of energy in the EU, seeking equilibrium among four criteria – access ...

  9. [Effect of Cognitive Behavioral Therapy on Sexual Satisfaction, Marital Adjustment, and Levels of Depression and Anxiety Symptoms in Couples with Vaginismus].

    Science.gov (United States)

    Şafak Öztürk, Cennet; Arkar, Haluk

    2017-01-01

    The aim of this study was to assess the effect of Cognitive Behavioral Therapy (CBT) on sexual functions of women with vaginismus and their husbands, their marital adjustment, and their levels of depression and anxiety symptoms. Twenty-six couples diagnosed as vaginismus according to DSM-IV-TR diagnostic criteria in gynecology outpatient clinics of Izmir Ege Maternity Hospital and Gynecological Diseases Training and Research Hospital were included in the study. The couples were treated with CBT through 50-minute sessions once a week. Pre- and post-treatment, all couples were assessed using a Personal Information Form, Golombok-Rust Inventory of Sexual Satisfaction, Dyadic Adjustment Scale, Beck Depression Inventory, and Beck Anxiety Inventory. There were significant differences in the total and all subscales' scores of sexual functions, significant increase in the marital adjustment, and a significant decrease in anxiety and depression symptom levels after CBT in women who completed the therapy (n = 20). In the husbands, significant recoveries were observed after the therapy in sexual functions total scores and subscales of satisfaction, avoidance, and impotence. However, there was no change in frequency, communication, sensuality, and in the premature ejaculation domains. Also, the marital adjustment scores increased, and significant decreases were observed in depression and anxiety symptom levels. It was observed that CBT is an appropriate therapy approach for vaginismus, and beneficial effects were observed in both women and their husbands in sexual functions, marital adjustment, and levels of depression and anxiety symptoms decreased.

  10. Ensuring GRID resource availability with the SAM framework in LHCb

    Science.gov (United States)

    Closier, J.; Paterson, S.; Santinelli, R.

    2008-07-01

    The LHCb experiment has chosen to use the SAM framework (Service Availability Monitoring Environment from EGEE-II) [1] make extensive tests of the LHCb environment at all the accessible grid resources. The availability and the proper definition of the local Computing and Storage Elements, user interfaces as well as the WLCG software environment are checked. The SAM framework is also used to pre-install the LHCb applications in the shared software area provided by each site. The deployment of the LHCb applications is based on a python tool developed inside the experiment. It is used for software management including incremental installation of interdependent packages and clean package removal. After the application software is installed a validation test of the whole MC chain is run. According to the results of the experiment specific SAM tests, the sites are (re)integrated into the LHCb production system managed by DIRAC [2]. The possibility of automated dynamic site certification using the SAM test suite is explored. This paper will describe the various ways of the LHCb use of the SAM framework. Practical experience in the recent production runs, current limitations and future developments will be presented.

  11. IT Services Availability during the CERN Annual Closure 2005

    CERN Multimedia

    2005-01-01

    Mail, CERN Windows (NICE), Web services, LXPLUS, LXBATCH, AFS, the automated tape devices, Castor, CDS Search, Submit and Agenda, InDiCo, EDMS (in collaboration with TS Department), Campus Network, Remedy, and Security services will be available during the CERN annual closure. All production databases will remain available (but not development databases such as devdb and devdb10). Problems occuring on scheduled services should be addressed within about half a day, except around Christmas Eve and Christmas Day (24 and 25 December) and New Year's Eve and New Year's Day (31 December and 1st January). As far as administrative computings services are concerned, ERT (Electronic Recruitment Tool) and PPT (Project Progress Tracking) for EGEE will be the only operational services; all other AIS applications such as EDH, CET, HRT, etc. will be unavailable from Wednesday 21/12 12:00 to Thursday 5/01/2005 8:00. The CERN LCG Production Services will be run on a 'best effort” basis. All other services (such as the ...

  12. Exergetic analysis and evaluation of a new application of gas engine heat pumps (GEHPs) for food drying processes

    Energy Technology Data Exchange (ETDEWEB)

    Gungor, Aysegul [Department of Mechanical Engineering, Faculty of Engineering, Gediz University, Izmir (Turkey); Erbay, Zafer [Department of Food Engineering, Faculty of Engineering, Ege University, 35100 Izmir (Turkey); Hepbasli, Arif [Department of Mechanical Engineering, Faculty of Engineering, Ege University, 35100 Izmir (Turkey)

    2011-03-15

    In this study, three medicinal and aromatic plants (Foeniculum vulgare, Malva sylvestris L. and Thymus vulgaris) were dried in a pilot scale gas engine driven heat pump drier, which was designed, constructed and installed in Ege University, Izmir, Turkey. Drying experiments were performed at an air temperature of 45 C with an air velocity of 1 m/s. In this work, the performance of the drier along with its main components is evaluated using exergy analysis method. The most important component for improving the system efficiency is found to be the gas engine, followed by the exhaust air heat exchanger for the drying system. An exergy loss and flow diagram (the so-called Grassmann diagram) of the whole drying system is also presented to give quantitative information regarding the proportion of the exergy input dissipated in the various system components, while the sustainability index values for the system components are calculated to indicate how sustainability is affected by changing the exergy efficiency of a process. Gas engine, expansion valve and drying ducts account for more than 60% amount of exergy in the system. The exergetic efficiency values are in the range of 77.68-79.21% for the heat pump unit, 39.26-43.24% for the gas engine driven heat pump unit, 81.29-81.56% for the drying chamber and 48.24-51.28% for the overall drying system. (author)

  13. De Fábrica 'fundo de quintal' a empresa multinacional: o caso de uma aliança ítalo-brasileira sob o enfoque da abordagem estruturacionista da estratégia como prática De fábrica 'fondo de patio' a una empresa multinacional: el estudio de caso de una alianza ítalo-brasileña en el enfoque estructuracionista de la estrategia-como-práctica From home industry to multinational company: a case study of an Italian-Brazilian alliance under the focus of the structurationist approach of strategy-as-practice

    Directory of Open Access Journals (Sweden)

    Maísa Gomide Teixeira

    2012-08-01

    Full Text Available O objetivo deste artigo é investigar indícios estruturacionistas, decorrentes de uma aliança estratégica interorganizacional, que possam ter resultado na mudança de uma fábrica fundo de quintal para uma empresa multinacional. Atingiu-se esse objetivo realizando um estudo de caso na empresa subsidiária brasileira do setor de máquinas e componentes para móveis, atual líder do mercado. Atentou-se para as considerações de Johanson e Vahlne (2006, com relação às implicações dos relacionamentos interorganizacionais em termos de aprendizagem e oportunidades. Concordando com as crescentes exigências para elucidar a prática estratégica no cotidiano das empresas, adotou-se a abordagem de estratégia como prática em complementaridade com a teoria da estruturação para balizar o exame à indispensável ligação entre pessoas, atividades e o contexto mais amplo. Os resultados destacam diversas alterações nas atividades da empresa filial permeando as seguintes etapas da aliança: (i pré-aliança; (ii durante a parceria; e (iii após a joint-venture. Para ilustrar como os elementos de práxis, práticas e praticantes estariam relacionados nessas diferentes fases do relacionamento interorganizacional, uma adaptação do gráfico de Whittington (2006 é proposta. Conclui-se apresentando um quadro com as principais atividades e ferramentas envolvidas na adaptação da empresa ao longo da aliança, entre as quais se enfatizam as práticas de mobilidade dos funcionários e do compromisso de relacionamento. Para melhor entender a forma como as alianças estratégicas afetam as empresas de bens de capital e verificar se há um padrão recorrente em termos do envolvimento de práticas, práxis e praticantes nas etapas de relacionamento, semelhante ao que está se propondo, considera-se apropriado realizar um trabalho comparativo. Dessa forma, poder-se-ia fazer inferências sobre as condições de escopo e transferibilidade.El objetivo de este

  14. The conceptions of learning science for science-mathematics groups and literature-mathematics groups in Turkey

    Science.gov (United States)

    Sadi, Ozlem; Lee, Min-Hsien

    2015-05-01

    Background:The conceptions of learning have a deep effect on the learning process, and accordingly on learning outcomes. Some researchers emphasize that conceptions of learning are domain-dependent and there should be more research in different domains (e.g. science, literature) to enhance students' understanding of conceptions of learning science. Purpose:The purpose of this research was to examine and compare science-major and literature-major students' conceptions of learning science (COLS). Also, gender differences in COLS were examined for two majors. Sample:The sample for this study comprised of 503 high school students in 10th, 11th, and 12th grades (244 females, 259 males) in a district of Karaman in Turkey. Design and methods:The questionnaire, the Conceptions of Learning Science (COLS), developed by Lee, Johanson, and Tsai, was used to identify students' COLS. The data obtained via the questionnaire were analyzed by means of SPSS 15.0 statistical software. Exploratory and confirmatory factor analyses were used to examine the factor structure of the questionnaire. Then, two-way MANOVA was conducted to compare the mean scores regarding the students' majors and genders in terms of the factors of COLS. Results:The results of the study revealed that students in Science-Mathematics field tended to express more agreement with lower-level COLS, such as learning science by 'memorizing,' 'preparing for exams,' and 'increasing one's knowledge' than those in Literature-Mathematics field. Second, more female students conceptualized learning science as 'increasing one's knowledge,' 'applying,' 'understanding,' or 'seeing in a new way' than male students in both majors. Third, the findings of two-way MANOVA, in general, revealed that there were significant differences in the average scores of conceptions of 'memorizing,' 'calculating and practicing,' and 'increasing one's knowledge' between two majors. Furthermore, there was a statistically significant mean difference

  15. Randomized crossover study in patients with neuroendocrine tumors to assess patient preference for lanreotide Autogel® given by either self/partner or a health care professional

    Directory of Open Access Journals (Sweden)

    Johanson V

    2012-10-01

    Full Text Available Viktor Johanson,1 Benedicte Wilson,2 Anna Abrahamsson,3 Constantin Jianu,4 Jan Calissendorff,5 Najme Wall,6 Henning Grønbæk,7 Jon Florholmen,8 Anders Öhberg,9 Dan Granberg101Department of Surgery, Sahlgrenska University Hospital, Göteborg, Sweden; 2Department of Medical Gastroenterology, Odense University Hospital, Odense, Denmark; 3Karolinska Institutet, Department of Hepatology, Karolinska University Hospital, Huddinge, Sweden; 4Department of Gastroenterology and Liver Disease, St Olav Hospital, Trondheim, Norway; 5Karolinska Institutet, Department of Endocrinology, Metabolism and Diabetes, Karolinska University Hospital, Solna, Sweden; 6Department of Oncology, Linköping University Hospital, Linköping, Sweden; 7Department of Medicine V, Aarhus University Hospital, Aarhus, Denmark; 8Department of Gastroenterology and Nutrition, University Hospital of North Norway, Tromsø, Norway; 9Medical Department, Ipsen AB, Stockholm, Sweden; 10Department of Medical Sciences, Section of Endocrine Oncology, Uppsala University, Uppsala, SwedenBackground: Lanreotide Autogel® is supplied in prefilled syringes. Therefore, it is possible for patients with neuroendocrine tumors to use self-/partner-administered injections. The primary objective of this study was to assess the proportion of patients preferring self/partner injections over injections administered by health care professionals, and to describe the impact of self/partner administration on efficacy, safety, and costs.Methods: Of 62 eligible patients, 26 (42% patients with neuroendocrine tumors treated with a stable dose of lanreotide Autogel 90 mg or 120 mg every 4 weeks agreed to participate in this Phase IV, international, open-label, crossover study, conducted at hospitals in Sweden, Norway, and Denmark. Patients were randomized to two blocks, starting with administration of lanreotide Autogel by either self/partner or a health care professional. Preference for injections administered by self

  16. Temperature trend estimates in the troposphere over Antarctica by use of analysis of the GPS radio occultation data

    Science.gov (United States)

    Zhang, Kefei; Fu, Erjiang; Wang, Chuan-Sheng; Liou, Yuei-An; Pavelyev, Alexander; Kuleshov, Yuriy

    2010-05-01

    Analyses of the Antarctic climate change during recent decades have demonstrated a positive continent-wide average near-surface temperature trend. Strong warming of the Antarctic Peninsula in contrast to slight cooling of the Antarctic continental interior in the last five decades has been emphasised [Turner et al. 2005]. Recently, it has been reported that significant warming of the Antarctic ice-sheet surface extends well beyond the Antarctic Peninsular to cover most of West Antarctica with a warming rate exceeding 0.1°C per decade over the past 50 years, and is strongest in winter and spring [Steig et al. 2009]. Assessments of atmospheric temperature trends have also found significant warming of the Antarctic winter troposphere. Analysing data from nine Antarctic radiosonde stations, it has been shown that regional midtropospheric temperatures have increased at a statistically significant rate of 0.5 to 0.7°C per decade over the past three decades - a major warming of the Antarctic winter troposphere that is larger than any previously identified regional tropospheric warming on Earth [Turner et al. 2006]. Analysis of climate change over the Polar Regions is particularly challenging due to the scarcity of observations from a small number of sparsely located weather stations. Obviously, data obtained by various satellite remote sensing techniques are invaluable in order to obtain spatially-complete distributions of near-surface and atmospheric temperature trends in high latitudes. For example, using the climate quality records of satellite Microwave Sounding Unit (MSU) observations, it has been shown that significant tropospheric warming prevails during Antarctic winters and springs, with the largest winter tropospheric warming of about 0.6°C per decade for 1979-2005 between 120°W and 180°W [Johanson and Fu 2007]. Recently, a new atmospheric observation technique, GPS radio occultation (RO), has been developed for acquiring the Earth's atmospheric

  17. 人類胚胎幹細胞專利與胚胎保護 ― 一部 98/44/EC 指令各自表述 Human Embryonic Stem Cell Patent and Protection of Embryos Controversies Surrounding Directive 98/44/EC

    Directory of Open Access Journals (Sweden)

    陳英鈐 In-Chin Chen

    2006-06-01

    Full Text Available 許多專家相信,從早期胚胎取得的幹細胞最具彈性,可能導致生物醫學革命,甚至治療許多現今無可救藥的疾病。然而從胚胎取得幹細胞,可能摧毀胚胎。關於胚胎法律與道德地位的爭議,也深深影響著予胚胎幹細胞相關發明的可專利性。歐洲專利公約本即規定,發明之公開或商業利用違反公序良俗者,不與專利。被整合進歐洲專利公約的歐洲生物科技指令更例示,複製人類的方法、改變人類生殖系基因同一性的方法以及為產業或商業目的使用人類胚胎不與發明專利。歐洲專利局與審查與異議部門迄今採取相當嚴格態度,禁止一切與胚胎幹細胞相關的產品與方法專利,德國、英國與瑞士 則在不同程度上容許之。 本文認為,TRIPS 第27 條第2 項規定,生物科技的發明原則上亦具 有可專利性,因此公序良俗條款及其例示規定應從嚴解釋,相關爭議包括EGE 第16 號意見,應由此加以批判性地檢視。 Many experts believe that human embryonic stem cells may lead to medical revolution and treat a lot of hitherto incurable diseases. Since embryos may be destroyed in this process, the controversies over the legal and ethical status of human embryos are extended to, weather inventions involving human embryonic stem cells are patentable. Article 53 (a EPC excludes the patentability of inventions the publication or exploitation of which would be contrary to “ordre public” or morality. Directive 98/44/EC, integrated into the EPC implementing regulations, illustrates the following examples as not patentable: the processes for cloning human beings; processes for modifying the germ line genetic identity of human beings and uses of human embryos for industrial or commercial purposes. The Examining and Opposition Divisions of EPO exclude from patentability all inventions involving human embryonic stem cells. Since

  18. Serologic evidence of equine granulocytic anaplasmosis in horses from central West Brazil Evidência sorológica de anaplasmose granulocítica equina em equinos do Centro-oeste Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Augusto Salvagni

    2010-09-01

    Full Text Available Ehrlichiosis is a zoonotic disease caused by gram-negative and intracellular obligatory bacterial organisms. Equine Granulocytic Anaplasmosis - EGA (formerly Equine Granulocytic Ehrlichiosis, EGE is a seasonal disease, normally self-limited in horses. There are few reports in Brazil about this ehrlichial agent, as well as its natural vectors. Nowadays, veterinarians are considering the suspicion of EGA in horses with suggestive symptoms of ehrlichiosis and which do not respond to piroplasmosis treatment. The aim of the present study was to identify horses exposed to the agent A. phagocytophilum by serological and molecular techniques. Twenty equine blood and serum samples from the central West region of Brazil were evaluated by microscopic examination of buffy coat smear, enzyme-linked immunosorbent assay (ELISA, indirect fluorescent antibody test (IFAT and nested polymerase chain reaction (nPCR. Additionally, the serodiagnosis of Theileria equi by IFA and ELISA were carried out, as well as molecular diagnosis by nPCR. Thirteen (65% serum samples were positive for A. phagocytophilum by ELISA, but none of them were positive by buffy-coat smear examination or nPCR. Antibodies IgG anti-T. equi were detected in 18 (90% and 17 (85% horses by IFA and ELISA, respectively and the agent was detected in 9 (45% animals by nPCR. Our data may be considered as important information to understanding the occurrence of EGA and equine piroplasmosis in central West Brazil.A Erliquiose é uma doença zoonótica causada por bactérias gram-negativas e intracelulares obrigatórias. A Anaplasmose Granulocítica Equina - AGE (anteriormente denominada Erliquiose Granulocítica Equina, EGE é uma enfermidade sazonal, normalmente auto-limitante em equinos. No Brasil, existem poucos relatos deste agente erliquial, bem como de seus vetores naturais. Atualmente, veterinários têm levantado a suspeita de casos de AGE em equinos com sinais clínicos sugestivos de erliquiose e

  19. Poly(glycidyl ether)-Based Monolayers on Gold Surfaces: Control of Grafting Density and Chain Conformation by Grafting Procedure, Surface Anchor, and Molecular Weight.

    Science.gov (United States)

    Heinen, Silke; Weinhart, Marie

    2017-03-07

    For a meaningful correlation of surface coatings with their respective biological response reproducible coating procedures, well-defined surface coatings, and thorough surface characterization with respect to layer thickness and grafting density are indispensable. The same applies to polymeric monolayer coatings which are intended to be used for, e.g., fundamental studies on the volume phase transition of surface end-tethered thermoresponsive polymer chains. Planar gold surfaces are frequently used as model substrates, since they allow a variety of straightforward surface characterization methods. Herein we present reproducible grafting-to procedures performed with thermoresponsive poly(glycidyl ether) copolymers composed of glycidyl methyl ether (GME) and ethyl glycidyl ether (EGE). The copolymers feature different molecular weights (2 kDa, 9 kDa, 24 kDa) and are equipped with varying sulfur-containing anchor groups in order to achieve adjustable grafting densities on gold surfaces and hence control the tethered polymers' chain conformation. We determined "wet" and "dry" thicknesses of these coatings by QCM-D and ellipsometry measurements and deduced anchor distances and degrees of chain overlap of the polymer chains assembled on gold. Grafting under cloud point conditions allowed for higher degrees of chain overlap compared to grafting from a good solvent like ethanol, independent of the used sulfur-containing anchor group for polymers with low (2 kDa) and medium (9 kDa) molecular weights. By contrast, the achieved grafting densities and thus chain overlaps of surface-tethered polymers with high (24 kDa) molecular weights were identical for both grafting methods. Monolayers prepared from an ethanolic solution of poly(glycidyl ether)s equipped with sterically demanding disulfide-containing anchors revealed the lowest degrees of chain overlap. The ratio of the radius of gyration to the anchor distance (2 Rg/l) of the latter coating was found to be lower than 1

  20. Imidacloprid is degraded by CYP353D1v2, a cytochrome P450 overexpressed in a resistant strain of Laodelphax striatellus.

    Science.gov (United States)

    Elzaki, Mohammed Esmail Abdalla; Miah, Mohammad Asaduzzaman; Wu, Min; Zhang, Haomiao; Pu, Jian; Jiang, Ling; Han, Zhaojun

    2017-07-01

    Cytochrome P450s are associated with the metabolising of a wide range of compounds, including insecticides. CYP353D1v2 has been found to be overexpressed in an imidacloprid-resistant strain of Laodelphax striatellus. Thus, this study was conducted to express CYP353D1v2 in Sf9 cells as a recombinant protein, to assess its ability to metabolise imidacloprid. Western blot and carbon monoxide difference spectrum analysis indicated that the intact CYP353D1v2 protein had been successfully expressed in Sf9 insect cells. Catalytic activity tests with four traditional P450-activity-probing substrates found that the expressed CYP353D1v2 preferentially metabolised p-nitroanisole, ethoxycoumarin and ethoxyresorufin with specific activities of 32.70, 0.317 and 1.22 pmol min-1 pmol-1 protein respectively, but no activity to luciferin-H EGE. The enzyme activity for degrading imidacloprid was tested by measuring substrate depletion and formation of the metabolite. Kinetic parameters for imidacloprid were Km 5.99 ± 0.95 µm and kcat 0.03 ± 0.0004 min-1 . The chromatogram analysis showed clearly the NADPH-dependent depletion of imidacloprid and the formation of an unknown metabolite. The UPLC-MS mass spectrum demonstrated that the metabolite was an oxidative product of imidacloprid, 5-hydroxy-imidacloprid. These results suggest that CYP353D1v2 in L. striatellus is capable of degrading imidacloprid, and that enzyme activity can be evaluated well only by some traditional probing substrates. © 2017 Society of Chemical Industry. © 2017 Society of Chemical Industry.

  1. FermiGrid—experience and future plans

    Science.gov (United States)

    Chadwick, K.; Berman, E.; Canal, P.; Hesselroth, T.; Garzoglio, G.; Levshina, T.; Sergeev, V.; Sfiligoi, I.; Sharma, N.; Timm, S.; Yocum, D. R.

    2008-07-01

    Fermilab supports a scientific program that includes experiments and scientists located across the globe. In order to better serve this community, Fermilab has placed its production computer resources in a Campus Grid infrastructure called 'FermiGrid'. The FermiGrid infrastructure allows the large experiments at Fermilab to have priority access to their own resources, enables sharing of these resources in an opportunistic fashion, and movement of work (jobs, data) between the Campus Grid and National Grids such as Open Science Grid (OSG) and the Worldwide LHC Computing Grid Collaboration (WLCG). FermiGrid resources support multiple Virtual Organizations (VOs), including VOs from the OSG, EGEE, and the WLCG. Fermilab also makes leading contributions to the Open Science Grid in the areas of accounting, batch computing, grid security, job management, resource selection, site infrastructure, storage management, and VO services. Through the FermiGrid interfaces, authenticated and authorized VOs and individuals may access our core grid services, the 10,000+ Fermilab resident CPUs, near-petabyte (including CMS) online disk pools and the multi-petabyte Fermilab Mass Storage System. These core grid services include a site wide Globus gatekeeper, VO management services for several VOs, Fermilab site authorization services, grid user mapping services, as well as job accounting and monitoring, resource selection and data movement services. Access to these services is via standard and well-supported grid interfaces. We will report on the user experience of using the FermiGrid campus infrastructure interfaced to a national cyberinfrastructure - the successes and the problems.

  2. FermiGrid - experience and future plans

    Energy Technology Data Exchange (ETDEWEB)

    Chadwick, K.; Berman, E.; Canal, P.; Hesselroth, T.; Garzoglio, G.; Levshina, T.; Sergeev, V.; Sfiligoi, I.; Timm, S.; Yocum, D.; /Fermilab

    2007-09-01

    Fermilab supports a scientific program that includes experiments and scientists located across the globe. In order to better serve this community, Fermilab has placed its production computer resources in a Campus Grid infrastructure called 'FermiGrid'. The FermiGrid infrastructure allows the large experiments at Fermilab to have priority access to their own resources, enables sharing of these resources in an opportunistic fashion, and movement of work (jobs, data) between the Campus Grid and National Grids such as Open Science Grid and the WLCG. FermiGrid resources support multiple Virtual Organizations (VOs), including VOs from the Open Science Grid (OSG), EGEE and the Worldwide LHC Computing Grid Collaboration (WLCG). Fermilab also makes leading contributions to the Open Science Grid in the areas of accounting, batch computing, grid security, job management, resource selection, site infrastructure, storage management, and VO services. Through the FermiGrid interfaces, authenticated and authorized VOs and individuals may access our core grid services, the 10,000+ Fermilab resident CPUs, near-petabyte (including CMS) online disk pools and the multi-petabyte Fermilab Mass Storage System. These core grid services include a site wide Globus gatekeeper, VO management services for several VOs, Fermilab site authorization services, grid user mapping services, as well as job accounting and monitoring, resource selection and data movement services. Access to these services is via standard and well-supported grid interfaces. We will report on the user experience of using the FermiGrid campus infrastructure interfaced to a national cyberinfrastructure--the successes and the problems.

  3. Potential impact of viral load and genetic makeup of HIV type 1 on mother-to-child transmission: characterization of env-C2V3C3 and nef sequences.

    Science.gov (United States)

    Pádua, Elizabeth; Parreira, Ricardo; Tendeiro, Rita; Nunes, Baltazar; Castela, João; Soares, Isabel; Mouzinho, Ana; Reis, Eduarda; Paixão, Maria Teresa

    2009-11-01

    HIV-1 mother-to-child transmission (MTCT) was evaluated in terms of the molecular characterization of the env and nef genomic regions and quantification of maternal RNA viral loads. Assignment of viral subtype was achieved by direct sequencing of PCR 1172 products amplified from proviral DNA in 45 HIV-1-nontransmitting mothers (NTM), along with 13 pairs of HIV-1-transmitting mothers (TM) and their infected children (C). Analysis of the env C2V3C3 and nef sequences revealed that subtypes G and B, and their genetic combinations (AG, BG), accounted for over 84.5% of all viruses identified. The genetic structure form envA-nefG was the most commonly observed, with a lower frequency in the NTM (13.3%) compared to the TM (23.1%) group. A greater number of genetic forms was observed among NTM, namely the presence of sequences assigned to subtypes D and F, as well as the intergenetic A/J, and C/U, recombinant forms, along with a mosaic provirus with a complex putative envA-nefEGE genetic structure. No significant differences were found when RNA viral loads were evaluated as a function of the viral subtypes. Nevertheless, a relatively high quantification of HIV-1 RNA was obtained in the NTM group, emphasizing the importance of the compliance and effectiveness of therapeutic schemes to control viral replication and reduce the risk of HIV vertical transmission. V3 sequences displaying features associated with the R5 phenotype dominated in both groups. Both C2V3C3 and Nef's functional domains were conserved during HIV-1 vertical transmission.

  4. Evaluation of School of health students' ethics position in Turkey.

    Science.gov (United States)

    Şen, Emine; Dal, Nursel Alp; Üstün, Çağatay; Okursoy, Algın

    2017-03-01

    The advances in science and technology increasingly lead to the appearance of ethical issues and to the complexity of care. Therefore, it is important to define the ethics position of students studying in health departments so that high quality patient care can be achieved. The aim of this study was to examine the ethics position of the students at Shool of Health of an University in western Turkey. The study design was descriptive and cross-sectional. The study population included 540 first, second, third, and fourth year students from the Departments of Nursing, Midwifery, and Rescue and Disaster Management in the 2013-2014 academic year. Data were collected with a Personal Identification Form and The Ethics Position Questionnaire. Obtained data were analyzed with Chi-square test, Confirmatory Factor Analysis, and Nested Analysis of Variance. Ethical considerations: Before conducting the research, approval was obtained from Ege University Clinical Research Ethics Committee in İzmir and written informed consent was taken from all the participants. There was no significant difference in the mean scores for the Ethics Position Questionnaire between the students in terms of years and fields of study. Although the mean scores for the subscale idealism did not differ between fields of study, the mean scores significantly differed between years of study. However, the mean scores for the subscale relativism did not differ in terms of years and fields of study. Whether students are idealistic or relativistic in terms of ethical judgment will be effective in ethical decision-making skills during patient care. Therefore, we need to define the factors that influence students' ethics position in the future. It is suggested that the courses and practices that teach students to be aware of their ethics position to create an ethical outlook can be placed in the curriculum in health schools.

  5. Şehir akvaryumlarında ele alınan Türkiye deniz balıkları türlerinin araştırılması.

    Directory of Open Access Journals (Sweden)

    Kemal Burak Gültekin

    2015-12-01

    Full Text Available Dünya çapında halk akvaryumlarına ve deniz canlılarına olan ilgi giderek artmaktadır. Bu duruma paralel olarak Türkiye’de de halk akvaryumları ilgi çekmeye başlamıştır. Çalışmada İstanbul, Ankara, Bursa ve Antalya’da bulunan halk akvaryumlarındaki sistemler ve sergilenen türler incelenmiş, yetkilileri ile yüz yüze görüşmeler yapılmıştır. Çalışma sonucunda, Chondrichthyes (kıkırdaklı balıklar grubundan 4 ordo ve 8 familyaya ait 8 tür, Osteichthyes (kemikli balıklar grubundan ise 9 ordo ve 24 familya ait 59 tür olmak üzere toplamda 67 adet Türkiye sularından kayıt edilmiş balık türü tespit edilmiştir. Tespit edilen türlerin habitatları incelendiğinde 57 türle en çok bentik türlerin halk akvaryumlarında tercih edildiği görülmüştür. Bundan başka 6 adet semipelajik, 3 adet epipelajik ve 1 adet pelajik tür tespit edilmiştir. Ayrıca türlerin denizlerimizdeki dağılımı incelendiğinde Karadeniz’de bulunan 40, Marmara Denizi’nde bulunan 48, Ege Denizi’nde ve Akdeniz’de bulunan 62 türün halk akvaryumlarında sergilendiği belirlenmiştir

  6. İzmir Körfezi’nde Kancaağız Pisi balığının Citharus linguatula (L., 1758 bazı biyolojik özellikleri

    Directory of Open Access Journals (Sweden)

    Efe Ulutürk

    2016-01-01

    Full Text Available Bu çalışmada, İzmir Körfezi’nde kancaağız pisi balığının Citharus linguatula ,(L., 1758 bazı biyolojik özellikleri tespit edilmiştir. Ocak 2005–Mayıs 2006 tarihleri arasında, İzmir Körfezi’nden Egesüf Araştırma Gemisi’nden trol ağı ile aylık olarak toplam 2555 adet elde edilmiştir. Bireylerin I-VI yaş grupları arasında dağılım gösterdiği saptanmıştır. Minimum, maksimum ve ortalama total boy sırasıyla, 9.1cm, 23.9cm ve 15.90±0.096 cm’dir. Minimum, maksimum ve ortalama ağırlık sırasıyla, 5.02g, 105.34g ve 32.06±0.61 g’dır. Total boy-ağırlık ilişkisi esas alınarak hesaplanan boy ağırlık ilişkileri, W=0.005*L3.14, r= 0.98 olarak tespit edilmiştir. von Bertalanffy büyüme parametreleri tüm bireyler için Lt = 27.38 * [1-e-0.2142 (t+1.6353] olarak hesaplanmıştır.

  7. Integrating Xgrid into the HENP distributed computing model

    Energy Technology Data Exchange (ETDEWEB)

    Hajdu, L; Lauret, J [Brookhaven National Laboratory, Upton, NY 11973 (United States); Kocoloski, A; Miller, M [Department of Physics, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States)], E-mail: kocolosk@mit.edu

    2008-07-15

    Modern Macintosh computers feature Xgrid, a distributed computing architecture built directly into Apple's OS X operating system. While the approach is radically different from those generally expected by the Unix based Grid infrastructures (Open Science Grid, TeraGrid, EGEE), opportunistic computing on Xgrid is nonetheless a tempting and novel way to assemble a computing cluster with a minimum of additional configuration. In fact, it requires only the default operating system and authentication to a central controller from each node. OS X also implements arbitrarily extensible metadata, allowing an instantly updated file catalog to be stored as part of the filesystem itself. The low barrier to entry allows an Xgrid cluster to grow quickly and organically. This paper and presentation will detail the steps that can be taken to make such a cluster a viable resource for HENP research computing. We will further show how to provide to users a unified job submission framework by integrating Xgrid through the STAR Unified Meta-Scheduler (SUMS), making tasks and jobs submission effortlessly at reach for those users already using the tool for traditional Grid or local cluster job submission. We will discuss additional steps that can be taken to make an Xgrid cluster a full partner in grid computing initiatives, focusing on Open Science Grid integration. MIT's Xgrid system currently supports the work of multiple research groups in the Laboratory for Nuclear Science, and has become an important tool for generating simulations and conducting data analyses at the Massachusetts Institute of Technology.

  8. JAK/STAT pathway interacts with intercellular cell adhesion molecule (ICAM) and vascular cell adhesion molecule (VCAM) while prostate cancer stem cells form tumor spheroids.

    Science.gov (United States)

    Duzagac, Fahriye; Inan, Sevinc; Ela Simsek, Fatma; Acikgoz, Eda; Guven, Ummu; Khan, Shafiq A; Rouhrazi, Hadi; Oltulu, Fatih; Aktug, Huseyin; Erol, Ayse; Oktem, Gulperi

    2015-01-01

    JAK/STAT is an evolutionarily conserved pathway and very important for second messenger system. This pathway is important in malignant transformation and accumulated evidence indicates that this pathway is involved in tumorigenesis and progression of several cancers. It was possible to assume that activation of JAK/STAT pathway is associated with increase in the expressions of ICAM/1 and VCAM-1. In this study we hypothesized that when cells were maintained as spheroids or monolayers, the structure of cancer stem cells (CSCs) could show differentiation when compared with non-CSCs. DU-145 human prostate cancer cells were cultured using the Ege University molecular embryology laboratory medium supplemented wıth 10% fetal bovine serum. Clusters of differentiation 133 (CD133)(+high)/CD44(+high) prostate CSCs were isolated from the DU145 cell line by using BD FACSAria. CD133//CD44+ CSCs were cultured until confluent with 3% noble agar. The expression of these proteins in CSCs and non-CSCs was analyzed by immunohistochemistry. Different expression profiles were observed in the conventional two-dimensional (2D) and three-dimensional (3D) experimental model system when CSCs and non-CSCs were compared. Human prostate CSCs exhibited intense ICAM-1 and VCAM-1 immunoreaction when compared with non-CSCs. These findings were supported by the fact that VCAM-1 on the surface of cancer cells binds to its counterreceptor, the α4β1 integrin (also known as very-late antigen, VLA-4), on metastasis-associated macrophages, triggering VCAM-1-mediated activation of the phosphoinositide 3-kinase growth and survival pathway in cancer cells. The results of this study showed that changes in JAK/STAT pathway are related with adhesion molecules and could affect cancer progression.

  9. Cenk Alver1 • Hakan Ayyıldız2 • Aytaç Altın2* 1 Çanakkale Onsekiz Mart Üniversitesi Fen Bilimleri Enstitüsü Su Ürünleri Anabilim dalı, Tezioğlu Yerleşkesi, Çanakkale 2 Çanakkale Onsekiz Mart Üniversitesi Gökçeada Uygulamalı Bilimler Yüksek Okulu Balıkçılık Teknolojisi Bölümü, Gökçeada Çanakkale

    Directory of Open Access Journals (Sweden)

    Cenk Alver

    2016-03-01

    Full Text Available Bu çalışmada Kuzey Ege Denizinde 24 Mart – 15 Haziran 2015 tarihleri arasında zıpkın ile yakalanan ve Gökçeada’da karaya çıkarılan kılıç balığı, Xiphias gladius bireylerinin yaş ve büyüme özellikleri belirlenmiştir. Alt çene çatal boyları (LJFL 70 ile 174 cm ve ağırlıkları 4 – 69 kg arasında olan toplam 300 adet kılıç balığı analizlerde kullanılmıştır. Boy – ağırlık ilişkisi W = 5E-06L3,188 (R2 = 0,948 olarak hesaplanmıştır. Toplam 83 adet bireyden anal yüzgeç ışınları kullanılarak yaş tayinleri gerçekleştirilmiştir. Yapılan yaş tayinleri sonucunda, kılıç balıklarının 0 - 5 yaş arasında oldukları ve en fazla bireyin 2 yaşında olduğu tespit edilmiştir. Von Bertalanffy büyüme denklemi L∞ = 218,3; k = 0,193 ve t0 = -2,1031 olarak hesaplanmıştır

  10. Evaluation of neuropsychological symptoms and exposure to benzene, toluene and xylene among two different furniture worker groups in Izmir.

    Science.gov (United States)

    Mandiracioglu, Aliye; Akgur, Serap; Kocabiyik, Nesrin; Sener, Ufuk

    2011-10-01

    This study was conducted to determine whether there was any exposure to toluene, xylene and benzene and to assess the health impact of these solvents on workers in furniture enterprises in Karabaglar, Izmir. This cross-sectional study covered furniture enterprises in Karabaglar, Izmir. This study was comprised of an exposed group consisting of workers engaged in painting and varnishing and therefore exposed either directly or indirectly toluene, xylene and benzene in the workplace and the non-exposed group engaged in other aspects of production. While a total of 261 individuals completed questionnaires, 210 workers agreed to provide blood samples. Blood solvents levels were determined using gas chromatograph at Ege University, Intoxication Research and Application Centre. The modified EUROQUEST questionnaire was used to assess neuropsychological symptoms and neurological and general examination were performed. Occupational and exposure history, demographic and work-related information was collected. In this study of workers, blood toluene and benzene levels were found to be significantly higher among those engaged in painting and varnishing compared to those who perform other tasks. The average blood toluene and benzene concentrations among exposed workers were 6.95 times and 1.64 times respectively higher than those in the nonexposed groups. Smokers and participants who worked in excess of 8 hours/day had higher blood toluene and benzene levels. The most frequently work-related health complaints were back pain, allergies and asthma. No differences were found in the average scores in the neuropsychological symptoms questionnaire between exposed and non-exposed groups. Neurological examination of two individuals with these complaints revealed a loss of reflexes. The workers were unaware that they were being exposed to solvents at work. Tobacco smoke is a major source of internal exposure to benzene. Improving working conditions in furniture work places is a priority.

  11. Improving Security in the ATLAS PanDA System

    Science.gov (United States)

    Caballero, J.; Maeno, T.; Nilsson, P.; Stewart, G.; Potekhin, M.; Wenaus, T.

    2011-12-01

    The security challenges faced by users of the grid are considerably different to those faced in previous environments. The adoption of pilot jobs systems by LHC experiments has mitigated many of the problems associated with the inhomogeneities found on the grid and has greatly improved job reliability; however, pilot jobs systems themselves must then address many security issues, including the execution of multiple users' code under a common 'grid' identity. In this paper we describe the improvements and evolution of the security model in the ATLAS PanDA (Production and Distributed Analysis) system. We describe the security in the PanDA server which is in place to ensure that only authorized members of the VO are allowed to submit work into the system and that jobs are properly audited and monitored. We discuss the security in place between the pilot code itself and the PanDA server, ensuring that only properly authenticated workload is delivered to the pilot for execution. When the code to be executed is from a 'normal' ATLAS user, as opposed to the production system or other privileged actor, then the pilot may use an EGEE developed identity switching tool called gLExec. This changes the grid proxy available to the job and also switches the UNIX user identity to protect the privileges of the pilot code proxy. We describe the problems in using this system and how they are overcome. Finally, we discuss security drills which have been run using PanDA and show how these improved our operational security procedures.

  12. Functional characterization of the Tetranychus urticae CYP392A11, a cytochrome P450 that hydroxylates the METI acaricides cyenopyrafen and fenpyroximate.

    Science.gov (United States)

    Riga, M; Myridakis, A; Tsakireli, D; Morou, E; Stephanou, E G; Nauen, R; Van Leeuwen, T; Douris, V; Vontas, J

    2015-10-01

    Cyenopyrafen is a Mitochondrial Electron Transport Inhibitor (METI) acaricide with a novel mode of action at complex II, which has been recently developed for the control of the spider mite Tetranychus urticae, a pest of eminent importance globally. However, some populations of T. urticae are cross-resistant to this molecule, and cyenopyrafen resistance can be readily selected in the lab. The cytochrome P450s genes CYP392A11 and CYP392A12 have been strongly associated with the phenotype. We expressed the CYP392A11 and the CYP392A12 genes with T. urticae cytochrome P450 reductase (CPR) in Escherichia coli. CYP392A12 was expressed predominately as an inactive form, witnessed by a peak at P420, despite optimization efforts on expression conditions. However, expression of CYP392A11 produced a functional enzyme, with high activity and preference for the substrates Luciferin-ME EGE and ethoxycoumarin. CYP392A11 catalyses the conversion of cyenopyrafen to a hydroxylated analogue (kcat = 2.37 pmol/min/pmol P450), as well as the hydroxylation of fenpyroximate (kcat = 1.85 pmol/min/pmol P450). In addition, transgenic expression of CYP392A11 in Drosophila melanogaster, in conjunction with TuCPR, confers significant levels of fenpyroximate resistance. The overexpression of CYP392A11 in multi-resistant T. urticae strains, not previously exposed to cyenopyrafen, which had been indicated by microarray studies, was confirmed by qPCR, and it was correlated with significant levels of cyenopyrafen and fenpyroximate cross-resistance. The implications of our findings for insecticide resistance management strategies are discussed. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. INVERSION/EVERSION STRENGTH DYSBALANCE IN PATIENTS WITH MEDIAL TIBIAL STRESS SYNDROME

    Directory of Open Access Journals (Sweden)

    Oğuz Yüksel

    2011-12-01

    Full Text Available The main purpose of the study is to investigate the inversion/eversion muscle strength balance of the ankle in patients with medial tibial stress syndrome (MTSS. A dysbalance of these muscles may play a role in the pathophysiology of MTSS. Another aim is to measure the medial longitudinal arch and navicular drop in patients with MTSS. A total of 11 patients diagnosed with MTSS in the outpatient clinic of Ege University School of Medicine Sports Medicine Department were enrolled in this study. The control group consisted of 11 regularly exercising individuals. The mean age of the patient group and the control group was 21. 0 ± 1.9 years (18-23 years and 23.2 ± 2.9 years (18-27 years, respectively. A detailed exercise questionnaire was administered to all subjects. Isokinetic muscle strength testing was performed at 30°/sec and 120°/sec to assess invertor and evertor muscle strength of the ankle. Photographs of the weight bearing and non-weight bearing foot were taken to measure the medial longitudinal arch deformation and the navicular drop. At 30°/sec, the average eversion concentric strength was significantly higher in the patient group, and the inversion/eversion strength ratio was significantly higher in the control group (p 0.05. MTSS may occur without an increase of pronation indicators like medial longitudinal arch deformation or navicular drop. In such cases, one of the predisposing factors may be the strength dysbalance of the invertor/evertor muscles in favour of the evertor muscles. This observation may be of additional value in the prevention and therapy of MTSS.

  14. Grid today, clouds on the horizon

    Science.gov (United States)

    Shiers, Jamie

    2009-04-01

    By the time of CCP 2008, the largest scientific machine in the world - the Large Hadron Collider - had been cooled down as scheduled to its operational temperature of below 2 degrees Kelvin and injection tests were starting. Collisions of proton beams at 5+5 TeV were expected within one to two months of the initial tests, with data taking at design energy ( 7+7 TeV) foreseen for 2009. In order to process the data from this world machine, we have put our "Higgs in one basket" - that of Grid computing [The Worldwide LHC Computing Grid (WLCG), in: Proceedings of the Conference on Computational Physics 2006 (CCP 2006), vol. 177, 2007, pp. 219-223]. After many years of preparation, 2008 saw a final "Common Computing Readiness Challenge" (CCRC'08) - aimed at demonstrating full readiness for 2008 data taking, processing and analysis. By definition, this relied on a world-wide production Grid infrastructure. But change - as always - is on the horizon. The current funding model for Grids - which in Europe has been through 3 generations of EGEE projects, together with related projects in other parts of the world, including South America - is evolving towards a long-term, sustainable e-infrastructure, like the European Grid Initiative (EGI) [The European Grid Initiative Design Study, website at http://web.eu-egi.eu/]. At the same time, potentially new paradigms, such as that of "Cloud Computing" are emerging. This paper summarizes the results of CCRC'08 and discusses the potential impact of future Grid funding on both regional and international application communities. It contrasts Grid and Cloud computing models from both technical and sociological points of view. Finally, it discusses the requirements from production application communities, in terms of stability and continuity in the medium to long term.

  15. Surgical patient education: Turkish nursing students experiences.

    Science.gov (United States)

    Kaymakçi, Senay; Yavuz, Meryem; Orgun, Fatma

    2007-01-01

    Patient education has been widely used by medical schools and schools of nursing as a method for evaluating clinical performance. Training of patients provides a viable method for teaching and evaluating nurse practitioner students as they progress through their educational programs toward clinical competency. Evaluation of patient education experience provided objective and valid information regarding the students' delivery of didactic information and ability to apply knowledge in the clinical setting. The purpose of this article is to describe the preparation of materials for preoperative patient education and to evaluate patient education carried out by second-year students of the University Of Ege School Of Nursing. In this study, students, patients and lecturers evaluated patient education carried out by the nursing students. Criteria including relationships between people (listening, talking and communication ability), and behavior before education (prepare topic content, develop appropriate material for the topic, communicate which topic will be explained, etc.) and during education (attract listeners' attention to the topic, give information about the target, present the content and material of the subject well, etc.) were appraised. According to the results of evaluation, the education carried out by the students achieved the highest score from patients; the students gave the second-highest score. The lecturers gave scores that were lower than those of students and patients. At the end of this study, it has been found that patients were pleased with the education prepared according to their individual requirements and the students were pleased with giving education with the material they have prepared employing their own creativity.

  16. Characteristics of high-confinement modes in Alcator C Mod

    Energy Technology Data Exchange (ETDEWEB)

    Snipes, J.A.; Boivin, R.L.; Christensen, C.; Fiore, C.; Garnier, D.; Goetz, J.; Golovato, S.N.; Graf, M.; Granetz, R.S.; Greenwald, M.; Hubbard, A.; Hutchinson, I.H.; Irby, J.; LaBombard, B.; Marmar, E.S.; Niemczewski, A.; OShea, P.; Porkolab, M.; Stek, P.; Takase, Y.; Terry, J.L.; Umansky, M.; Wolfe, S.M. [Plasma Fusion Center, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 (United States)

    1996-05-01

    The regime of high particle and energy confinement known as the H mode [Phys. Rev. Lett. {bold 49}, 1408 (1982)] has been extended to a unique range of operation for divertor tokamaks up to toroidal fields of nearly 8 T, line-averaged electron densities of 3{times}10{sup 20} m{sup {minus}3}, and surface power densities of nearly 0.6 MW/m{sup 2} in the compact high-field tokamak Alcator C Mod [Phys. Plasmas {bold 1}, 1511 (1994)]. H modes are achieved in Alcator C Mod with Ion Cyclotron Resonant Frequency (ICRF) heating and with Ohmic heating alone without boronization of the all molybdenum tiled first wall. Large increases in charge exchange flux are observed during the H mode over the entire range of energies from 2 to 10 keV. There appears to be an upper limit to the midplane neutral pressure, of about 0.08 Pa above which no H modes have been observed. The plasmas with the best energy confinement have the lowest midplane neutral pressures, below 0.01 Pa. There is an edge electron temperature threshold such that {ital T}{sub {ital e}}{ge}280 eV {plus_minus}40 eV for sustaining the H mode, which is equal at L{endash}H and H{endash}L transitions. The hysteresis in the threshold power between L{endash}H and H{endash}L transitions is less than 25{percent} on average. Both core and edge particle confinement improve by a factor of 2{endash}4 from L mode to H mode. Energy confinement also improves by up to a factor of 2 over L mode. {copyright} {ital 1996 American Institute of Physics.}

  17. Vitamin D deficiency in pregnant women and their neonates in spring time in western Turkey.

    Science.gov (United States)

    Halicioglu, Oya; Aksit, Sadik; Koc, Feyza; Akman, Sezin A; Albudak, Esin; Yaprak, Isin; Coker, Isil; Colak, Ayfer; Ozturk, Can; Gulec, Ebru S

    2012-01-01

    Although Turkey is located in a sunny region, vitamin D deficiency is still a serious health problem in pregnant women and their infants, especially among the low socio-economic status Turkish population. This study was carried out in order to measure serum 25-hydroxyvitamin D3 [25(OH)D] concentrations of the pregnant women in the last trimester and in their neonates at delivery and to determine the factors associated with maternal serum 25(OH)D concentrations. Among the patients visiting the Ege Obstetrics and Gynecology Hospital in the period March to May 2008, 258 healthy pregnant women ≥37 weeks of gestation were included in this study. The information on different characteristics such as the number of pregnancies and births, nutritional status, vitamin and mineral support during gestation, educational status, clothing style and the economic level of the family was collected from women. Blood samples from the mothers and umbilical cord of the newborns were taken to measure 25(OH)D. The mean 25(OH)D concentrations of the mothers and their infants were 11.5 ± 5.4 ng/mL and 11.5 ± 6.8 ng/mL, respectively. We found a strong positive correlation between maternal serum and umbilical cord blood 25(OH)D concentrations (r = 0.651, P women had a covered dressing style. 25(OH)D concentrations of these covered dressing mothers and their infants were 9.7 ± 5.1 ng/mL and 9.7 ± 5.6 ng/mL, respectively, which were significantly lower compared with those of uncovered mothers and their babies (P nutritional status of the mothers. These findings suggest that much more effective vitamin D prophylaxis programmes should be implemented for pregnant women as well as for their babies. © 2011 Blackwell Publishing Ltd.

  18. Vibroacoustics of the piano soundboard: (Non)linearity and modal properties in the low- and mid-frequency ranges

    Science.gov (United States)

    Ege, Kerem; Boutillon, Xavier; Rébillat, Marc

    2013-03-01

    The piano soundboard transforms the string vibration into sound and therefore, its vibrations are of primary importance for the sound characteristics of the instrument. An original vibro-acoustical method is presented to isolate the soundboard nonlinearity from that of the exciting device (here: a loudspeaker) and to measure it. The nonlinear part of the soundboard response to an external excitation is quantitatively estimated for the first time, at ≈-40 dB below the linear part at the ff nuance. Given this essentially linear response, a modal identification is performed up to 3 kHz by means of a novel high resolution modal analysis technique [K. Ege, X. Boutillon, B. David, High-resolution modal analysis, Journal of Sound and Vibration 325 (4-5) (2009) 852-869]. Modal dampings (which, so far, were unknown for the piano in this frequency range) are determined in the mid-frequency domain where FFT-based methods fail to evaluate them with an acceptable precision. They turn out to be close to those imposed by wood. A finite-element modelling of the soundboard is also presented. The low-order modal shapes and the comparison between the corresponding experimental and numerical modal frequencies suggest that the boundary conditions can be considered as blocked, except at very low frequencies. The frequency-dependency of the estimated modal densities and the observation of modal shapes reveal two well-separated regimes. Below ≈1 kHz, the soundboard vibrates more or less like a homogeneous plate. Above that limit, the structural waves are confined by ribs, as already noticed by several authors, and localised in restricted areas (one or a few inter-rib spaces), presumably due to a slightly irregular spacing of the ribs across the soundboard.

  19. Mersin Bitkisi (Myrtus communis L.'nde Farklı Hasat Zamanlarının

    Directory of Open Access Journals (Sweden)

    Ayşe Betül AVCI

    2009-04-01

    Full Text Available Bu çalışma Ege Üniversitesi Ziraat Fakültesi Bornova araştırma alanında bulunan Mersin (Myrtus communis L. bitkilerinde farklı hasat zamanlarının uçucu yağ oranlarına etkisini araştırmak amacıyla yürütülmüştür. Araştırmada, Mersin bitkisinden Ekim 2002 tarihinden itibaren bir yıl boyunca her ayın 15'inde ve günün üç farklı saatinde (08:00, 13:00, 18:00 olacak şekilde yapraklı dal örnekleri alınmıştır. Mersin (Myrtus communis L. bitkisinde en yüksek uçucu yağ oranı ortalama % 0.725 ile Temmuz ayında saat 18.00'de yapılan hasatta, en düşük oran ise ortalama % 0.250 ile mart ayında saat 13.00'de yapılan hasatta elde edildiği gözlenmiştir. Yapılan LSD testine göre farklı aylara ve saatlere göre belirlenen uçucu yağ değerleri arasındaki fark istatistiksel açıdan önemli bulunmuştur.

  20. The Biometric Analysis of Pipefish Species from Çamaltı Lagoon (İzmir Bay, Aegean Sea.

    Directory of Open Access Journals (Sweden)

    Şule Gürkan

    2015-12-01

    Full Text Available Çamaltı Lagünü’ndeki (İzmir Körfezi, Ege Denizi deniziğnelerinin biyometrik analizleri. Bu araştırma, 2000-2002 yılları arasında İzmir Körfezi Çamaltı Lagünündeki üç deniziğnesi türünün, Syngnathus acus Linneaus, 1758, Syngnathus typhle Linneaus, 1758 ve Nerophis ophidion (Linneaus 1758, biyometrik analizleri verilmiştir. Araştırmada toplam 562 adet birey incelenmiştir. S.acus ve S.typhle için 10 morfometrik, 5 meristik karakter, N.ophidion için ise 9 morfometrik 3 meristik karakter incelenmiştir. S.acus’un dişi ve erkek bireyleri arasında sadece preanal (Pr.RN ve postanal (Po.RN halka sayıları bakımından farklılık bulunmuştur. Syngnathus typhle’de ise dişilerin ağız genişliği (MW, ağız yüksekliği (MH, göz çapı (ED, dorsal yüzgeç boyu (DFL erkeklerden daha büyük olup seksüel dimorfizim olarak değerlendirilmiştir. Nerophis ophidion’da ise dişilerin göz çapı (ED değerleri erkeklerine göre daha küçük olduğu belirlenmiştir

  1. Medical closure of patent ductus arteriosus does not reduce mortality and development of bronchopulmonary dysplasia in preterm infants

    Directory of Open Access Journals (Sweden)

    Demet Terek

    2014-01-01

    Full Text Available Background: Although, patent ductus arteriosus (PDA is associated with significant morbidity due to hemodynamic instability in preterm infants, the effect of ductus closure on mortality and morbidity is a controversial issue. The aim is to evaluate the efficacy of oral and intravenous (IV ibuprofen treatment on ductal closure and effects on mortality and bronchoplumonary dysplasia. Materials and Methods: The medical records of 292 premature infants treated at Ege University Neonatal Intensive Care Unit were retrospectively evaluated. Patients were classified into 3 groups as; No PDA, hemodynamically insignificant PDA (hiPDA and hemodynamically significant PDA (hsPDA according to the presence and hemodynamical significance of PDA by echocardiography. hsPDA group was treated with IV or oral ibuprofen. Results: Patent ductus arteriosus was diagnosed by routine echocardiography in 145 patients, of whom 78 (53.7% had hsPDA. All 65 infants with hiPDA had spontaneous PDA closure. Echocardiographic measurements were similar to those patients treated with oral or IV ibuprofen, as in the response rate to treatment without serious adverse effects. The presence of respiratory distress syndrome, surfactant therapy, late sepsis, bronchopulmonary dysplasia (BPD and mortality rates were significantly higher in patients with hsPDA. However, with stepwise logistic regression; 5th min Apgar score (odds ratio [OR], 1.321, 95% confidence interval [CI], 1.063-1.641, P = 0.012 and gestational age (OR, 1.422, 95% CI, 1.212-1.662, P < 0.001 were the only significant variables associated with mortality. Gestational age (OR, 0.680, 95% CI, 0.531-0.871, P = 0.002 was the only significant variable associated with BPD shown with logistic regression. Conclusion: Ibuprofen treatment is effective for hsPDA closure with minimal side effects. HiPDA can close spontaneously; therefore treatment decision should be individualized. However, medical treatment of PDA does not reduce

  2. Analysis and Modeling of Social In uence in High Performance Computing Workloads

    KAUST Repository

    Zheng, Shuai

    2011-06-01

    High Performance Computing (HPC) is becoming a common tool in many research areas. Social influence (e.g., project collaboration) among increasing users of HPC systems creates bursty behavior in underlying workloads. This bursty behavior is increasingly common with the advent of grid computing and cloud computing. Mining the user bursty behavior is important for HPC workloads prediction and scheduling, which has direct impact on overall HPC computing performance. A representative work in this area is the Mixed User Group Model (MUGM), which clusters users according to the resource demand features of their submissions, such as duration time and parallelism. However, MUGM has some difficulties when implemented in real-world system. First, representing user behaviors by the features of their resource demand is usually difficult. Second, these features are not always available. Third, measuring the similarities among users is not a well-defined problem. In this work, we propose a Social Influence Model (SIM) to identify, analyze, and quantify the level of social influence across HPC users. The advantage of the SIM model is that it finds HPC communities by analyzing user job submission time, thereby avoiding the difficulties of MUGM. An offline algorithm and a fast-converging, computationally-efficient online learning algorithm for identifying social groups are proposed. Both offline and online algorithms are applied on several HPC and grid workloads, including Grid 5000, EGEE 2005 and 2007, and KAUST Supercomputing Lab (KSL) BGP data. From the experimental results, we show the existence of a social graph, which is characterized by a pattern of dominant users and followers. In order to evaluate the effectiveness of identified user groups, we show the pattern discovered by the offline algorithm follows a power-law distribution, which is consistent with those observed in mainstream social networks. We finally conclude the thesis and discuss future directions of our work.

  3. The Role of Parafibromin, Galectin-3, HBME-1, and Ki-67 in the Differential Diagnosis of Parathyroid Tumors

    Directory of Open Access Journals (Sweden)

    Serap Karaarslan

    2015-11-01

    Full Text Available Objectives: Parathyroid carcinoma (PC is a rare parathyroid tumor compared to parathyroid adenoma (PA and atypical parathyroid adenoma (APA. Recent studies have suggested parafibromin has a role in the differential diagnosis of parathyroid tumors. We sought to determine the role of parafibromin as well as galectin-3, Ki-67, and HBME-1 as diagnostic markers in the differential diagnosis of parathyroid tumors. Methods: A total of 92 cases diagnosed with PA, APA, or PC at Sifa University and Private Ege Pathology Laboratory between 2006–2012 were included in the study. Parafibromin (microarray, galectin-3, Ki-67, and HBME-1 were evaluated using immunohistochemistry in all parathyroid tumors. Results: Eighty-four cases were diagnosed with PA, six with APA, and two with PC. The study group consisted of 82 females and 10 males. Their mean age was 50.9 years, and the mean tumor diameter was 1.97 cm. Parafibromin was negative in the two PC cases but positive in all APA and PA cases. Positivity was observed with galectin-3 in 17 adenoma cases, three atypical adenomas, and two carcinoma cases. Positivity with HBME-1 was found in 26 PA cases and one PC case. Parafibromin and galectin-3 expression was significant between the three tumor groups but not for HBME-1 expression. Parafibromin expression increased in PA whereas galectin-3 expression decreased. A statistical significance was found between the three tumor groups according to the Ki-67 score (p=0.010. Additionally, the Ki-67 proliferation index was under 1% in PAs. Conclusion: The number of PCs in our series was small so our data mostly reflects the immunohistochemical characteristics of PAs. Parafibromin expression, galectin-3 negativity, and a Ki-67 proliferation index under 1% were estimated as beneficial in the differential diagnosis of difficult parathyroid tumors.

  4. Comparison of isolated and concomitant liver injuries: is hepatic trauma entirely responsible for the outcome?

    Science.gov (United States)

    Yazici, P; Aydin, U; Sozbilen, M

    2010-01-01

    This study was undertaken to examine both isolated and concomitant liver injuries to clarify the role of liver trauma on outcome. This retrospective study was a review of all abdominal trauma patients who presented with liver injuries, with or without concomitant injury at Ege University School of Medicine over a 3-year period. Presentation, injury grade, management, and outcomes were analyzed. Patients with isolated hepatic injury (Group A) were compared with patients who had concomitant hepatic injury (liver and spleen/small bowel) (Group B). Significance was set at 95% confidence intervals. Of 368 patients, 80 (21%) presented with liver injury. Of these, the aetiology was as follows: 53 (66.2%) blunt injury, 19 (23%) penetrating injury, and 8 (10%) gun shot trauma. There were 38 patients in Group A and 42 in Group B. Of these 42 patients, 19 were diagnosed with serious types of injury ; eight thoracic, three open long bone fracture, one intra-cardiac, one intracranial. Six additional patients were observed with injuries to large abdominal vessels. Eleven patients (28.9%) with isolated hepatic injury were managed non-operatively. Mortality, intensive care unit and hospital length of stay, and transfusion requirements were significantly higher in Group B. Only the number of transfused blood units and the grade of liver injury were found to be effective on outcome whereas stepwise regression analysis revealed that injury type (penetrating) and blood transfusion were predictive for mortality. This study highlighted that although isolated liver injury results in good outcome with non-operative management, concomitant injuries to the liver lead to a higher failure and mortality rate. However, liver injury itself is rarely responsible for death.

  5. Discovery of cyclic spot activity on the G8 giant HD 208472

    Science.gov (United States)

    Özdarcan, O.; Evren, S.; Strassmeier, K. G.; Granzer, T.; Henry, G. W.

    2010-08-01

    % We present and analyze 17 consecutive years of U BV RI time-series photometry of the spotted giant component of the RS CVn binary HD 208472. Our aim is to determine the morphology and the evolution of its starspots by using period-search techniques and two-spot light-curve modelling. Spots on HD208472 always occur on hemispheres facing the observer during orbital quadrature and flip their location to the opposite hemisphere every approximately six years. The times when the spots change their preferential hemisphere correspond to times when the light curve amplitudes are the smallest and when abrupt changes of the photometric periods are observed. During these times the star is also close to a relative maximum brightness, suggesting a vanishing overall spottedness at each end of the previous cycle and the start of a new one. We find evidence for a 6.28±0.06-yr brightness cycle, which we interpret to be a stellar analog of the solar 11-year sunspot cycle. We also present clear evidence for a brightening trend, approximated with a 21.5±0.5-yr period, possibly due to a stellar analog of the solar Gleissberg cycle. From the two-spot modelling we also determine an upper limit for the differential-rotation coefficient of α=Δ P/P of 0.004±0.010, which would be fifty times weaker than on the Sun. Based on data obtained with the Amadeus T7 Automatic Photoelectric Telescope at Fairborn Observatory, jointly operated by the University of Vienna and AIP, the Tennessee State University T3 0.4 m APT at Fairborn Observatory, operated by Tennessee State University, and the telescopes of the Ege University Observatory in Izmir.

  6. A buccal cell model comet assay: Development and evaluation for human biomonitoring and nutritional studies

    Energy Technology Data Exchange (ETDEWEB)

    Szeto, Y.T. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong (China); School of Health Sciences, Macao Polytechnic Institute, Macao (China); Benzie, I.F.F. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong (China)]. E-mail: iris.benzie@inet.polyu.edu.hk; Collins, A.R. [Department of Nutrition, University of Oslo, Oslo (Norway); Choi, S.W. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong (China); Cheng, C.Y. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong (China); Yow, C.M.N. [Department of Health Technology and Informatics, Hong Kong Polytechnic University, Kowloon, Hong Kong (China); Tse, M.M.Y. [School of Nursing, Hong Kong Polytechnic University, Kowloon, Hong Kong (China)

    2005-10-15

    The comet assay is a widely used biomonitoring tool for DNA damage. The most commonly used cells in human studies are lymphocytes. There is an urgent need to find an alternative target human cell that can be collected from normal subjects with minimal invasion. There are some reports of buccal cells, collected easily from the inside of the mouth, being used in studies of DNA damage and repair, and these were of interest. However, our preliminary studies following the published protocol showed that buccal cells sustained massive damage and disintegrated at the high pH [O. Ostling, K.J. Johanson. Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells. Biochem. Biophys. Res. Commun. 123 (1984) 291-298] used, but that at lower pH were extremely resistant to lysis, an essential step in the comet assay. Therefore, the aims of this study were to develop a protocol than enabled buccal cell lysis and DNA damage testing in the comet assay, and to use the model to evaluate the potential use of the buccal cell model in human biomonitoring and nutritional study. Specifically, we aimed to investigate intra- and inter-individual differences in buccal cell DNA damage (as strand breaks), the effect of in vitro exposure to both a standard oxidant challenge and antioxidant treatment, as well as in situ exposure to an antioxidant-rich beverage and supplementation-related effects using a carotenoid-rich food. Successful lysis was achieved using 0.25% trypsin for 30 min followed by proteinase K (1 mg/ml) treatment for 60 min. When this procedure was performed on cells pre-embedded in agarose on a microscope slide, followed by electrophoresis (in 0.01 M NaOH, 1 mM EDTA, pH 9.1, 18 min at 12 V), a satisfactory comet image was obtained, though inter-individual variation was quite wide. Pre-lysis exposure of cells to a standard oxidant challenge (induced by H{sub 2}O{sub 2}) increased DNA strand breaks in a dose related manner, and incubation of cells in

  7. THE HANDBOOK OF BLENDED LEARNING:Global Perspectives, Local Designs

    Directory of Open Access Journals (Sweden)

    Reviewed by Alev ATES

    2009-10-01

    Full Text Available THE HANDBOOK OF BLENDED LEARNING:Global Perspectives, Local Designs Curtis J. Bonk (ed. and Charles R. Graham (ed., Jay Cross (Foreword,Micheal G. Moore Foreword ISBN: 978-0-7879-7758-0 Publisher: John Wiley & Sons, Inc. Pfeiffer Pages: 624 March 2006.Reviewed by Alev ATESPhD Student at Curriculum and Instruction,Lecturer at Computer Education and Instructional Technologies,Faculty of Education, Ege University, Izmir, TURKEYBlended learning or blended e-learning sounds like aconfusing term at first since it is relatively a new term fortoday‘s instructors. However, Moore reports that it can betraced as far back as the 1920s which was called ―supervisedcorrespondence study‖. For clarification of the term ―blendedlearning‖ and informing the instructors about its commonpractices worldwide, the book provides readers a comprehensive resource about blended learning. It aims to raise awareness of adopting BL from institutional perspectives of many chapter authors from Australia, Korea, Malaysia, the UK, Canada and South Africa who are distinguished people mostly in instructional technology era. With this book, I guess the editors aim at both showing the big picture at macro level and present micro level examples which provide details of blended learning applications among their strengths and weaknesses. As introduced in the book, one ofthe editors Curtis J. Bonk, a former corporate controller and CPA, is now professor of educational psychology as well as instructional systems technology at Indiana University; the other editor Charles R. Graham is an assistant professor of instructionalpsychology and technology at Brigham Young University with a focus on technologymediated teaching and learning.The book is of eight parts including 39 chapters besides two forewords. Therefore, theorganization of this review is considered to take a holistic view for each parts while emphasizing the original and/or impressive aspects that chapter authors provided

  8. The Eurasian Economic Union and the Silk Road Economic Belt: Opportunities for Russia

    Directory of Open Access Journals (Sweden)

    Igor Makarov

    2016-09-01

    Full Text Available This article considers the opportunities for Russia presented by the launch of China’s Silk Road Economic Belt initiative.This initiative is a comprehensive project for the rapid development of Central Asian countries, and not limited only to transportand logistics to guarantee the supply of Chinese goods to Europe. It is also China’s response to economic and political processes both within the country and in the Asia-Pacific region: the economic slow down and transformation of its social and economic model, diverging income levels, the growing presence of the United States in Asia, and the new divisions of labour within the region. The Silk Road initiative is based on China’s intention to create strong regional value chains, to outsource labour-intensive and environmentally harmful production, to foster the development of north west China including securing political stability in the Xinjiang Uighur Autonomous Region, and to guarantee the use of Chinese construction firms’ capacity. Goods transit is a secondary priority and justified not by commercial benefits from using land routes, but by the need to diversify export risks, arising due to the deteriorating military and political situation in the South China Sea. The 2015 Joint Statement on Cooperation on the Construction of Joint Eurasian Economic Union and the Silk Road Economic Belt projects resolves the issue of all egedly competitive goals of these complementary projects. The Eurasian Economic Union (EEU provides an institutional base for cooperation while the Silk Road initiative provide investments for their development. Russia may benefit from participating in the Silk Road initiative. First, it would help integrate its transportation system into the region’s logistics network and provide additional opportunities for transit and associated logistical services as well as access to growing regional markets. Second, the Silk Road initiative offers opportunities to strengthen

  9. Maksimum Yagıslar için Süreden Bagımsız Bir Bölgesel Model Yaklasımı

    Directory of Open Access Journals (Sweden)

    Ömer Levend AŞIKOĞLU

    2009-04-01

    Full Text Available Bu çalısmada, Ege Bölgesi örneginde belli tekerrürlü standart süreli yıllık maksimum yagıs (SSMY tahmininde kullanılabilecek, Lognormal tabanlı bir bölgesel model gelistirilmistir. Bölgesel modellerin temel amacı, proje alanına yakın birkaç istasyondaki noktasal veri ve bilgilerin proje alanına aktarılması ile ortaya çıkacak sakıncaları en aza indirmektir. Ayrıca, bölgesel modeller yardımıyla plüvyografsız istasyon bulunan veya hiç istasyon bulunmayan proje alanlarına da bilgi aktarma olanagı mevcuttur. Çalısmada, Lognormal dagılım fonksiyonunun tanımlanması için gerekli olan degiskenlik katsayısının yagıs süresinden bagımsız oldugu belirlenmis, tüm bölge için süreden bagımsız bir "bölgesel degiskenlik katsayısı" kullanılmıstır. Bölgesel degiskenlik katsayısının kullanımıyla gelistirilen "boyutsuz bölgesel tekerrür egrisi", proje alanında ortalama yagıs yüksekligi bilinen her noktada verilen tekerrüre karsılık gelecek yagıs yüksekliginin hesaplanmasını saglayacaktır. Böylelikle bölgede daha etkin boyutsuz yagıs tahminleri yapılabilmesine imkan verecektir. Bu model, yagıs ölçüm istasyonlarının standart süreli yagısları Lognormal frekans dagılım modeline uyan bölgelerde, bölgesel model kurma açısından büyük kolaylıklar getirecektir.

  10. JTS and its Application in Environmental Protection Applications

    Science.gov (United States)

    Atanassov, Emanouil; Gurov, Todor; Slavov, Dimitar; Ivanovska, Sofiya; Karaivanova, Aneta

    2010-05-01

    The environmental protection was identified as a domain of high interest for South East Europe, addressing practical problems related to security and quality of life. The gridification of the Bulgarian applications MCSAES (Monte Carlo Sensitivity Analysis for Environmental Studies) which aims to develop an efficient Grid implementation of a sensitivity analysis of the Danish Eulerian Model), MSACM (Multi-Scale Atmospheric Composition Modeling) which aims to produce an integrated, multi-scale Balkan region oriented modelling system, able to interface the scales of the problem from emissions on the urban scale to their transport and transformation on the local and regional scales), MSERRHSA (Modeling System for Emergency Response to the Release of Harmful Substances in the Atmosphere) which aims to develop and deploy a modeling system for emergency response to the release of harmful substances in the atmosphere, targeted at the SEE and more specifically Balkan region) faces several challenges: These applications are resource intensive, in terms of both CPU utilization and data transfers and storage. The use of applications for operational purposes poses requirements for availability of resources, which are difficult to be met on a dynamically changing Grid environment. The validation of applications is resource intensive and time consuming. The successful resolution of these problems requires collaborative work and support from part of the infrastructure operators. However, the infrastructure operators are interested to avoid underutilization of resources. That is why we developed the Job Track Service and tested it during the development of the grid implementations of MCSAES, MSACM and MSERRHSA. The Job Track Service (JTS) is a grid middleware component which facilitates the provision of Quality of Service in grid infrastructures using gLite middleware like EGEE and SEEGRID. The service is based on messaging middleware and uses standart protocols like AMQP (Advanced

  11. Dosimetry in radiotherapy and brachytherapy by Monte-Carlo GATE simulation on computing grid; Dosimetrie en radiotherapie et curietherapie par simulation Monte-Carlo GATE sur grille informatique

    Energy Technology Data Exchange (ETDEWEB)

    Thiam, Ch.O

    2007-10-15

    Accurate radiotherapy treatment requires the delivery of a precise dose to the tumour volume and a good knowledge of the dose deposit to the neighbouring zones. Computation of the treatments is usually carried out by a Treatment Planning System (T.P.S.) which needs to be precise and fast. The G.A.T.E. platform for Monte-Carlo simulation based on G.E.A.N.T.4 is an emerging tool for nuclear medicine application that provides functionalities for fast and reliable dosimetric calculations. In this thesis, we studied in parallel a validation of the G.A.T.E. platform for the modelling of electrons and photons low energy sources and the optimized use of grid infrastructures to reduce simulations computing time. G.A.T.E. was validated for the dose calculation of point kernels for mono-energetic electrons and compared with the results of other Monte-Carlo studies. A detailed study was made on the energy deposit during electrons transport in G.E.A.N.T.4. In order to validate G.A.T.E. for very low energy photons (<35 keV), three models of radioactive sources used in brachytherapy and containing iodine 125 (2301 of Best Medical International; Symmetra of Uro- Med/Bebig and 6711 of Amersham) were simulated. Our results were analyzed according to the recommendations of task group No43 of American Association of Physicists in Medicine (A.A.P.M.). They show a good agreement between G.A.T.E., the reference studies and A.A.P.M. recommended values. The use of Monte-Carlo simulations for a better definition of the dose deposited in the tumour volumes requires long computing time. In order to reduce it, we exploited E.G.E.E. grid infrastructure where simulations are distributed using innovative technologies taking into account the grid status. Time necessary for the computing of a radiotherapy planning simulation using electrons was reduced by a factor 30. A Web platform based on G.E.N.I.U.S. portal was developed to make easily available all the methods to submit and manage G

  12. White matter alterations related to attention-deficit hyperactivity disorder and COMT val158met polymorphism: children with valine homozygote attention-deficit hyperactivity disorder have altered white matter connectivity in the right cingulum (cingulate gyrus

    Directory of Open Access Journals (Sweden)

    Kabukcu Basay B

    2016-04-01

    Full Text Available Burge Kabukcu Basay,1 Ahmet Buber,1 Omer Basay,1 Huseyin Alacam,2 Onder Ozturk,1 Serkan Suren,3 Ozlem Izci Ay,4 Cengizhan Acikel,5 Kadir Agladioglu,6 Mehmet Emin Erdal,4 Eyup Sabri Ercan,7 Hasan Herken21Child and Adolescent Psychiatry Department, Pamukkale University Medical Faculty, Denizli, 2Psychiatry Department, Pamukkale University Medical Faculty, Denizli, 3Medical Park Samsun Hospital, Samsun, 4Medical Biology and Genetics Department, Mersin University Medical Faculty, Mersin, 5Biostatistics Department, GATA (GMMA, Ankara, 6Radiology Department, Pamukkale University Medical Faculty, Denizli, 7Child and Adolescent Psychiatry Department, Ege University Medical Faculty, Izmir, TurkeyIntroduction: In this article, the COMT gene val158met polymorphism and attention-deficit hyperactivity disorder (ADHD-related differences in diffusion-tensor-imaging-measured white matter (WM structure in children with ADHD and controls were investigated.Patients and methods: A total of 71 children diagnosed with ADHD and 24 controls aged 8–15 years were recruited. Using diffusion tensor imaging, COMT polymorphism and ADHD-related WM alterations were investigated, and any interaction effect between the COMT polymorphism and ADHD was also examined. The effects of age, sex, and estimated total IQ were controlled by multivariate analysis of covariance (MANCOVA.Results: First, an interaction between the COMT val158met polymorphism and ADHD in the right (R cingulum (cingulate gyrus (CGC was found. According to this, valine (val homozygote ADHD-diagnosed children had significantly lower fractional anisotropy (FA and higher radial diffusivity (RD in the R-CGC than ADHD-diagnosed methionine (met carriers, and val homozygote controls had higher FA and lower RD in the R-CGC than val homozygote ADHD patients. Second, met carriers had higher FA and axial diffusivity in the left (L-uncinate fasciculus and lower RD in the L-posterior corona radiata and L

  13. [The relationship between mobbing and depression syndrome in the female working population of service industry: the problem statement and the prevention strategies in Sicilian environment].

    Science.gov (United States)

    Romano, C; De Giovanni, L; Santoro, P E; Spataro, M

    2007-01-01

    The concept of "work" and the social interactions in the workplace contribute to develop the working satisfaction and the social and personal identity of the adult. The aim of the survey is that of checking up on the presence of a statistically significant relation between The Depression Syndrome and The Mobbing Phenomenon. It is necessary to understand and value if and how some of the employer's behaviours could have a heavy influence on the worker's psychophysical condition, up to causing a state of anxiety and depression. It has been used the now famous "LIPT" (Leymann Inventory of Psychological Terror), elaborated by Leymann at the beginning of the 90's. It is a short anonymous questionnaire recognized all over Europe as a standard to confirm the Mobbing existence in organizational contexts. The current version of the questionnaire is called "LIPT EGE", a more suitable tool to check the seven parameters of the Mobbing determination, as well as the quantification of the consequent harm. Some scales for depressive symptoms evaluation have been added to the Mobbing questionnaire: The Self Rating Depression Scale (SDS) and The Depression Status Inventory (DSI) of Zung. The questionnaires are administered to 500 workers women in public and private corporation in Sicily, exactly in Siracusa and Catania provinces. 206 women aged 34-50 have answered the questionnaires. In addition to the age and the sex, the distinction variables of the examined people are the position in the firm, nationality, vocational qualification, and the yearly gross income. The research has begun in july and has continued on august 2006. Attention has been focused only on the administrative sectors. Through the chi2 test and the exact Fisher test, the dependence between the changeable presence of depression in the two questionnaires (Zung 1 and Zung 2) and every single variable of the questionnaire on the Mobbing has been pointed out. In particular, the results establish a connection between

  14. Anxiety of first cadaver demonstration in medical, dentistry and pharmacy faculty students.

    Science.gov (United States)

    Bati, Ayse Hilal; Ozer, Mehmet Asim; Govsa, Figen; Pinar, Yelda

    2013-07-01

    Anatomy is the fundamental of medical and health professional education. Anatomic dissection enables the examination of the organs in the human cadavers systematically and topographically. The aim of this study was to determine the effect of the first cadaver demonstration and the anxiety of medical, dental and pharmacy students. A questionnaire was distributed to 486 students in the same academic year (2009-2010) at Ege University. The review of anxiety reveals the circumstances such as exhaustion, stress, depression, anxiety, destructive life, deterioration of mental or physical quality or asthenia (over-fatigue), professionally having a serious effect on the students. 486 (85.3 %) students in total participated in this research carried out as based on voluntariness as 338 (93.9 %) students from the medical faculty, 78 (70.9 %) students from the faculty of dentistry and 70 (70 %) students from the faculty of pharmacy.A medium level of anxiety was detected in the students in their first encounter with the cadaver. The state anxiety score (SAS) average taken by all the students who took part in the research is 42.6 ± 5.60 and trait anxiety score average is 46.6 ± 5.0. No discrepancy was detected among the faculties with respect to anxiety score. While the SASs of the male students were higher than the girls, the trait anxiety scores of the girl students were detected to be higher than male students. While the characteristics and the cultural life of our society force the male students into stronger behavioral patterns, they may actually increase their anxiety level in distressed conditions. The fact that trait anxiety is high in both sexes, particularly in female students can be explained by the patient responsibility and the work load undertaken in the professions in the medical field as early as the period of education.Before the students' applied lessons with the cadavers start, a preparatory session must be planned for this education to decrease the

  15. FOTOVOLTAiK SiSTEMLERiN DENETLENMESi iÇiN YENi BiR KONTROL KARTI VE BiLGiSAYAR YAZILIMI

    Directory of Open Access Journals (Sweden)

    Mustafa Berkant SELEK

    2008-02-01

    Full Text Available Bu çalısmada, İzmir ili Bornova ilçesindeki Ege Üniversitesi Günes Enerjisi Enstitüsü bünyesinde kurulan bir yenilenebilir enerji sisteminin elektrik akısını kontrol eden bir mikroislemci kartı tasarlanmıs ve bilgisayar yazılımı gelistirilmistir. Bu amaçla, anahtarlama görevi yapan güç elektronigi devre elemanlarının bulundugu ayrı bir elektronik kartın kontrol islemini üstlenen PIC18F452 mikrodenetleyicisi kullanan bir elektronik devre gerçeklestirilmistir. Piyasadaki standart kontrol kartları tek seviyeli eviricilerin anahtarlanmasına olanak saglamaktadır. Gelistirilen kontrol kartı ise çok seviyeli eviricilerle çalısmak üzere tasarlanmıstır. Bunun yanı sıra, günes enerjisi panellerinin verimleri oldukça düsük oldugundan, günes panellerinin maksimum güç noktasında (MPP çalıstırmak çok önemlidir. Bu yüzden, tasarlanan kontrol kartı üzerinde MPP algoritması da bulunmaktadır. Ayrıca, tasarlanan kontrol kartının üzerinde RS232 seri haberlesme arabirimi mevcuttur. Böylece, kontrol kartı üzerinde gerçeklestirilen tüm fonksiyonların kullanıcının istegine göre bir bilgisayar yazılımı aracılıgı ile seçilebilmesine ve istenirse kullanıcıya rapor olarak verilebilmesine olanak tanınmıstır. Son olarak, gelistirilen kontrol kartının, gelistirdigimiz yazılım ile haberlesebilmesi için bir komut seti olusturulmustur. Böylece, kendi kontrol kartını gelistirmek isteyen veya daha görsel bir yazılım gelistirmek isteyen diger arastırmacılar için ortak bir taban olusturulması hedeflenmistir.

  16. Incidence of Parasitic Diarrhea in Patients with Common Variable Immune Deficiency.

    Science.gov (United States)

    Uysal, Serhat; Tunalı, Varol; Akdur Öztürk, Eylem; Ardeniz, Ömür; Işıkgöz Taşbakan, Meltem; Pullukçu, Hüsnü; Özensoy Töz, Seray; Turgay, Nevin; Arda, Bilgin

    2016-06-01

    Parasites might cause atypical and severe infections in immunocompromised hosts. The prevalence of diarrhea among common variable immune deficiency (CVID) syndrome patients varies between 20% and 94%, which indicates that diarrhea and gastrointestinal system (GIS) complaints could be the second leading cause of morbidity in CVID patients after respiratory tract infections. This study aimed to assess the prevalence of intestinal parasites in CVID patients with GIS complaints and diarrhea. In this study, all cases followed up in the Immunology and Allergy Clinic of Ege University School of Medicine from July 2008 to August 2015 with the diagnosis of CVID were reviewed retrospectively. The stool samples of patients with diarrhea were identified using direct microscopy of native (0.09% NaCl) and Lugol's iodine preparations followed by formol-ethyl acetate concentration to apply modified Kinyoun, trichrome, acid-fast trichrome, and modified trichrome stains for the presence of intestinal parasites. Overall, 26 of 37 CVID patients had diarrhea; white and red blood cells (WBCs and RBCs, respectively) were identified in 11 and 10 of these 26 samples, respectively. Intestinal parasites were found to be present in 7 of the 11 patients with WBCs and 3 of the 10 patients with RBCs. With the addition of patients who neither had WBCs nor RBCs in their stool, a parasitic agent was detected in 13 (50%) of the 26 patients with diarrhea. There was no significant difference between the diarrheic patients with or without intestinal parasites with respect to cramps, fever, nausea and vomiting, tenesmus, bloody feces, and presence of mucus in the stool. Only one patient had malabsorption, which was not associated with intestinal parasites. The most common parasites detected in this study were Cryptosporidium spp. (n=9; 69.2%), Giardia spp. (n=7; 53.8%), and Blastocystis spp. (n=3; 23.1%). We also identified that parasitic diarrhea in CVID patients tended to last longer (M (mean): 16

  17. Atıksu Arıtma Tesisinin Diyatom (Bacillariophyceae Tür Komposizyonuna Etkileri.

    Directory of Open Access Journals (Sweden)

    Fatma Çolak Sabancı

    2015-12-01

    Full Text Available Ege denizi’nin ötrofik körfezi olan İzmir Körfezi’nin fitoplankton tür komposizyonu 1998-2000-2001 ve 2002 yıllarında iç, orta, dış körfezde yer alan 14 istasyonda mevsimsel ve kalitatif olarak incelendi. Bu araştırmanın sonuçlarına göre, İzmir Körfezi’nde Cyanophyceae, Dinophyceae, Dictyochophyceae, Bacillariophyceae olmak üzere 4 alg sınıfı ve Ciliata olmak üzere bir protozooplankton sınıfına ait türler saptanmıştır. Bu sınıflar içersinde tür sayısı bakımından Dinophyceae sınıfının diğer sınıflara oranla daha baskın olduğu bulunmuştur. Çiğli Atık Su Arıtma Tesisi ünitesinin 2000 yılının sonlarında devreye girmesini takiben tür çeşitliliğinde önemli düzeyde değişimler olduğu saptandı. Saptanan türlerin kalitatif tür matrisi üzerinde gerçekleştirilen hiyerarşik kümelendirme ve çok boyutlu ölçeklendirme analizlerinin sonuçlarına göre, tür assosiyasyonlarının belirlenmesi ve istasyonlar arasındaki benzerliklerin çıkartılması amaçlandı

  18. Investigation of the speech results of posterior pharyngeal wall augmentation with fat grafting for treatment of velopharyngeal insufficiency.

    Science.gov (United States)

    Dinsever Eliküçük, Çağla; Kulak Kayıkcı, Maviş Emel; Esen Aydınlı, Fatma; Çalış, Mert; Özgür, Fatma Figen; Öztürk, Mehtap; Günaydın, Rıza Önder

    2017-06-01

    The purpose of this study was to evaluate the speech results of posterior pharyngeal wall augmentation (PPWA) with fat grafting both in the early and late postoperative period, and to clarify the impact of the procedure concomitant with speech therapy. This is a prospective case-control study. The study involved 87 cleft palate ± cleft lip patients with velopharyngeal insufficiency (VPI) who has been treated with PPWA. Patients were separated into two groups according to age; the first group consisted of 49 pediatric participants between 6 and 12 years of age and the second group consisted of 38 adolescent participants between 13 and 18 years of age. Preoperative velopharyngeal function and articulation were compared postoperatively at the following time points: the 3rd month, 12th month, 18th month and 24th month. The velopharyngeal function was evaluated with regards to the velopharyngeal closure type and velopharyngeal closure amount, by using the pediatric flexible nasoendoscopy and the nasometer methods. In the nasometer evaluation, nasalance sores were measured by using nonsense syllables and meaningful sentences. The Ankara Articulation Test (AAT) (Ege et al., 2004) was used to detect compensatory articulation products secondary to VPI. Consonant production error types and frequencies were determined according the guidelines stated in the study of Hardin-Jones et al. (2009). These were Pharyngeal Fricatives - Posterior Nasal Fricatives/Stop Production, Glottal Stop Production, Middorsum Palatal Stop Production, Nasal Frictional Production, Posterior Nasal Frictional Production/Phoneme Specific Nasal Emission, use of Nasal Consonants for Oral Consonants, and Replacement of Trills. All the participants received concurrent speech therapy four times, twice in the post-operative period between 1 and 3 months and twice between 3 and 6 months. PPWA improved the speech performance from the 18th month to 24th month of the postoperative period. AAT assessment of

  19. Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress

    Directory of Open Access Journals (Sweden)

    Arun MZ

    2016-04-01

    Full Text Available Mehmet Zuhuri Arun,1 Buket Reel,1 Graciela B Sala-Newby,2 Mark Bond,2 Aikaterini Tsaousi,2 Perry Maskell,2 Andrew C Newby21Department of Pharmacology, Faculty of Pharmacy, Ege University, Izmir, Turkey; 2Bristol Heart Institute, University of Bristol, Bristol Royal Infirmary, Bristol, UK Background: Bisphosphonates, including zoledronate, target osteoclasts and are widely used in the treatment of osteoporosis and other bone resorption diseases, despite side effects that include damaging the stomach epithelium. Beneficial and adverse effects on other organ systems, including the cardiovascular system, have also been described and could impact on the use of bisphosphonates as therapeutic agents. Vascular smooth muscle cells (VSMCs are major constituents of the normal vascular wall and have a key role in intimal thickening and atherosclerosis, in part by secreting MMPs that remodel the extracellular matrix and cleave cell surface proteins or secreted mediators. In this study, we investigated the effects of zoledronate on MMP expression.Methods: Rat VSMCs were stimulated by PDGF (50 ng/mL plus TNF-α (10 ng/mL or left unstimulated for a further 24 hours in serum-free medium. In other series of experiments, cells were pre-treated either with SC-514 (50 µM or with apocynin (20 nM for 2 hours, then zoledronate (100 µM was added into 2% fetal calf serum containing medium for 24 hours.Results and discussion: Using isolated rat VSMCs in culture, zoledronate (100 µM increased MMP-9 and -13 mRNA expressions but inhibited MMP-2 expression. MMP-9 and MMP-13 up-regulation was shown to depend on the NF-κB pathway; and this was activated by zoledronate. Furthermore, zoledronate elevated the levels of reactive oxygen species detected by either dichlorofluorescein in isolated VSMCs or lucigenin enhanced chemiluminescence in rat aortic rings in vitro. Apocynin, an inhibitor of NADPH oxidase, reversed NF-κB activation and MMP-9 and MMP-13 up-regulation by

  20. Vibroacoustics of the piano soundboard: Reduced models, mobility synthesis, and acoustical radiation regime

    Science.gov (United States)

    Boutillon, Xavier; Ege, Kerem

    2013-09-01

    In string musical instruments, the sound is radiated by the soundboard, subject to the strings excitation. This vibration of this rather complex structure is described here with models which need only a small number of parameters. Predictions of the models are compared with the results of experiments that have been presented in Ege et al. [Vibroacoustics of the piano soundboard: (non)linearity and modal properties in the low- and mid-frequency ranges, Journal of Sound and Vibration 332 (5) (2013) 1288-1305]. The apparent modal density of the soundboard of an upright piano in playing condition, as seen from various points of the structure, exhibits two well-separated regimes, below and above a frequency flim that is determined by the wood characteristics and by the distance between ribs. Above flim, most modes appear to be localised, presumably due to the irregularity of the spacing and height of the ribs. The low-frequency regime is predicted by a model which consists of coupled sub-structures: the two ribbed areas split by the main bridge and, in most cases, one or two so-called cut-off corners. In order to assess the dynamical properties of each of the subplates (considered here as homogeneous plates), we propose a derivation of the (low-frequency) modal density of an orthotropic homogeneous plate which accounts for the boundary conditions on an arbitrary geometry. Above flim, the soundboard, as seen from a given excitation point, is modelled as a set of three structural wave-guides, namely the three inter-rib spacings surrounding the excitation point. Based on these low- and high-frequency models, computations of the point-mobility and of the apparent modal densities seen at several excitation points match published measurements. The dispersion curve of the wave-guide model displays an acoustical radiation scheme which differs significantly from that of a thin homogeneous plate. It appears that piano dimensioning is such that the subsonic regime of acoustical

  1. Serum CCL-18 level is a risk factor for COPD exacerbations requiring hospitalization

    Directory of Open Access Journals (Sweden)

    Dilektasli AG

    2017-01-01

    Full Text Available Asli Gorek Dilektasli,1 Ezgi Demirdogen Cetinoglu,1 Esra Uzaslan,1 Ferah Budak,2 Funda Coskun,1 Ahmet Ursavas,1 Ilker Ercan,3 Ercument Ege1 1Department of Pulmonary Disesaes, 2Department of Immunology, 3Department of Biostatistics, Uludag University Faculty of Medicine, Bursa, Turkey Introduction: Chemokine (C-C motif ligand 18 (CCL-18 has been shown to be elevated in chronic obstructive pulmonary disease (COPD patients. This study primarily aimed to evaluate whether the serum CCL-18 level differentiates the frequent exacerbator COPD phenotype from infrequent exacerbators. The secondary aim was to investigate whether serum CCL-18 level is a risk factor for exacerbations requiring hospitalization. Materials and methods: Clinically stable COPD patients and participants with smoking history but normal spirometry (NSp were recruited for the study. Modified Medical Research Council Dyspnea Scale, COPD Assessment Test, spirometry, and 6-min walking test were performed. Serum CCL-18 levels were measured with a commercial ELISA Kit. Results: Sixty COPD patients and 20 NSp patients were recruited. Serum CCL-18 levels were higher in COPD patients than those in NSp patients (169 vs 94 ng/mL, P<0.0001. CCL-18 level was significantly correlated with the number of exacerbations (r=0.30, P=0.026, although a difference in CCL-18 values between infrequent and frequent exacerbator COPD (168 vs 196 ng/mL subgroups did not achieve statistical significance (P=0.09. Serum CCL-18 levels were significantly higher in COPD patients who had experienced at least one exacerbation during the previous 12 months. Overall, ROC analysis revealed that a serum CCL-18 level of 181.71 ng/mL could differentiate COPD patients with hospitalized exacerbations from those who were not hospitalized with a 88% sensitivity and 88.2% specificity (area under curve: 0.92. Serum CCL-18 level had a strong correlation with the frequency of exacerbations requiring hospitalization (r=0.68, P<0

  2. Otolith morphometry and population parameters of red porgy, Pagrus pagrus (Linnaeus, 1758 in Saros Bay (North Aegean Sea.

    Directory of Open Access Journals (Sweden)

    Ali İşmen

    2015-12-01

    Full Text Available Bu çalışmada, Kuzey Ege Denizi’nde (Saroz Körfezi Fangri balığının toplam boy (TL ile toplam ağırlık (TW arasındaki ilişki, yaş, büyüme ve otolit boyu (OL - otolit ağırlığı (OW, balık boyu (TL - otolit boyu (OL, balık ağırlığı (TW - otolit boyu (OL, otolit boyu (OL - otolit genişliği (OWi arasındaki morfometrik ilişkiler incelenmiştir. Toplam 100 adet balık üzerinde yapılan ölçümlerde minimum boy 9,6 cm, maksimum boy 44,4 cm; minimum ağırlık 17,1 g, maksimum ağırlık 1372,5 g olarak tespit edilmiştir. Otolit ağırlığı minimum 0,0181 g, maksimum 0,1456 g; otolit boyu minimum 0,52 cm, maksimum 1,17 cm olarak ölçülmüştür. Boy-ağırlık ilişkisi TW=0,021*TL2,885 (r2=0,98, otolit boyu - otolit ağırlığı OW=0,105*OL2,609 (r2=0,92, toplam boy - otolit boyu OL=0,024*TL+0,249 (r2=0,83 otolit boyu - toplam ağırlık OL=0,235*TW0,237 (r2=0,81 otolit boyu - otolit genişliği OWi=0.501*OL+0.116 (r2=0.832 ilişkileri tespit edilmiştir. En büyük yaş 9 olarak belirlenmiş, von Bertalanffy büyüme parametreleri L∞=51,59 cm, K=0,12 yıl-1ve t0= -1,13 yıl olarak hesaplanmıştır

  3. Lineamenti di una Moderna Lotta Antifrana

    Directory of Open Access Journals (Sweden)

    A. Belluigi

    1965-06-01

    Full Text Available L'A. inizia col rilevare l'alto contributo di calamità'lavoro, spese che le situazioni di frana (numerosissime e ravvivantesi, comportanoin Italia.Accenna subito dopo che, purtroppo, non si tiene nel dovuto contole pur innumeri « zone sospette » che si maturano quasi sempre con segnipremonitori, lasciati a se stessi, senza nessuna « Istituzione specifica permanente», dedita al rilevamento (triangolazioni aggiornate, clinografie,tensio e pressiografle, spie estensimetriche, vibrografie, ecc..Si illustrano i concetti di « autogenesi di frana », autoctona o allactona,« ipocentri di frana » che si attivano post-incubazioni di autotensioni (equilibridi minima stabilità, da cui dipartono quelle « direttrici di rottura »che, nei corpi elastici uniformi, si identificano con le « tensioni principalielastiche » v. Mastrodicasa: « Dissesti statici delle strutture edilizie » Hoepli,1965.Definito geomeccanicamente il « suolo reale », si mostra come sonotraslatabili i risultati ottenuti — con presupposto bidimensionale dei « sistemipiani di tensione » — ai solidi tridimensionali rocciosi. 11 presupposto bidimensionale non è affatto limitativo, e la relativa teorica deduttivasi utilizza in pieno, tenendo conto degli « ipocentri di frana », unanuova prassi perciò per risalire alla « superficie di scorrimento » dei massifranosi (non più induttivamente come si fa quasi sempre oggigiorno.L'A. espone i criteri (numerosi e cruciali, per ben stabilire i « breaks »di frana, misure e dati permanenti, occasionali, formulare le condizionidi stabilità, in base a leggi geomatematiche, intensificare la ricerca ipocentrale,fino a pervenire possibilmente ad un «presagio di valanga» (con vibrografi,analisi fotoelastiche, ecc. che dia tempo di applicare soprattuttoi metodi moderni di ristrutturizzazione elettrogeocinetici.Vengono a grandi linee illustrati tali metodi che vanno, più propriamente,dall'elettrogeosmosi agli elettrogetti (EGE

  4. Materials for advanced power engineering 2006. Proceedings of the 8th Liege conference. Pt. 3

    Energy Technology Data Exchange (ETDEWEB)

    Lecomte-Beckers, J.; Carton, M.; Schubert, F.; Ennis, P.J. (eds.)

    2006-07-01

    The European Co-operation in the field of Scientific and Technical Research (COST) is a well-established organisation for the co-ordination of national research and development programmes on the European level. The series of Liege conferences began in 1978 with the aim of disseminating the results of the COST Action 50 in which materials for gas turbines were investigated. Since then, a Liege Conference has been held every four years and the results of COST Actions 501 and 522, which were concerned with materials for power generation plant, reported. At this, the Eighth Li ege Conference, the materials research and development work being carried out in the current COST Actions 536 'Alloy Development for Critical Components of Environmentally Friendly Steam Power Plant' with the acronym ACCEPT and 538 'High Temperature Plant Lifetime Extension' will be reported. Reliable energy supply at reasonable cost is one of the most important factors in the development and maintenance of the modern industrial society, but there are increasing concerns about the environmental impact of energy production as well as about the need to conserve valuable energy resources for future generations. New and emerging energy technologies are of great interest, but fossil fuels will continue to make a considerable contribution to energy requirements into the foreseeable future. The emphasis in this field is therefore on the most efficient use of fossil fuels, which can be achieved by increasing the thermal efficiency of the energy conversion process. For steam power plant and gas turbines, this means raising the temperature and pressure of the process. This in turn requires the application of improved materials that are able to withstand the increasingly arduous service conditions. In the COST Actions, the materials research and development activities that are necessary for the critical components of advanced, highly efficient power generation plant have been based on

  5. Composition of uppermost mantle beneath the Northern Fennoscandia - numerical modeling and petrological interpretation

    Science.gov (United States)

    Virshylo, Ivan; Kozlovskaya, Elena; Prodaivoda, George; Silvennoinen, Hanna

    2013-04-01

    restricted volume in the multi-dimensional parameter space. In order to constrain concentration of minerals we used equilibrium of mineral associations for selected P-T condition obtained by free Gibbs energy minimization (c.f. Stixrude & Lithgow-Bertelloni, 2005). We also considered the mineralogical composition of upper mantle xenoliths, although the representativeness of xenoliths in Precambrian rocks could be treated with care, if one tries to describe the modern mantle. As a first step, we estimated 1D model of mineralogical composition in the depth range of 35-350 km using the IASP91 reference model (Kennett & Engdahl, 1991). Both the P- and S- wave velocities were used for inversion, in order to improve the reliability of the model. More comprehensive result could be obtained if density distribution is involved. In our study we used the 1D PEMC density model (Dziewonski, Hales & Lapwood, 1975) as it is the most adequate for the continental lithosphere. The 1D modeling showed that the garnet lherzolite model (forsterite, fayalite, enstatite, ferrosilite, diopside, jadeite, pyrope) can be considered as a basic one. The end-members of olivine and orthopyroxene solutions were included with the aim of Fe/Mg ratio estimation. Testing with modified models including hedenbergite, harzburgite spinel, etc. showed that these minerals have no significant influence on bulk elastic properties. Selected set of minerals allows modelling the most species of peridote-pyroxenite associations known from xenoliths investigations (Kukkonen, Kuusisto, Lehtonen, & Peltonen, 2008; Lehtonen, O'Brien, Peltonen, Johanson, & Pakkanen, 2004). However, there exist also a number of evidences for mantle eclogite xenoliths from the region under study and its surrounding (Lehtonen et al., 2004; Peltonen, Kinnunen, & Huhma, 2002). That is why we also made modelling for garnet-clinopyroxene model of eclogite. The volumetric mineral compositions obtained were transformed into weight concentration of rock

  6. Redisposition of phoma-like anamorphs in Pleosporales.

    Science.gov (United States)

    de Gruyter, J; Woudenberg, J H C; Aveskamp, M M; Verkley, G J M; Groenewald, J Z; Crous, P W

    2013-06-30

    , Verkley & Crous, Subplenodomus Gruyter, Verkley & Crous. New species: Aposphaeria corallinolutea Gruyter, Aveskamp & Verkley, Paraconiothyrium maculicutis Verkley & Gruyter. New combinations: Coniothyrium carteri (Gruyter & Boerema) Verkley & Gruyter, C. dolichi (Mohanty) Verkley & Gruyter, C. glycines (R.B. Stewart) Verkley & Gruyter, C. multiporum (V.H. Pawar, P.N. Mathur & Thirum.) Verkley & Gruyter, C. telephii (Allesch.) Verkley & Gruyter, Heterospora (Boerema, Gruyter & Noordel.) Gruyter, Verkley & Crous, H. chenopodii (Westend.) Gruyter, Aveskamp & Verkley, H. dimorphospora (Speg.) Gruyter, Aveskamp & Verkley, Leptosphaeria errabunda (Desm.) Gruyter, Aveskamp & Verkley, L. etheridgei (L.J. Hutchison & Y. Hirats.) Gruyter, Aveskamp & Verkley, L. macrocapsa (Trail) Gruyter, Aveskamp & Verkley, L. pedicularis (Fuckel) Gruyter, Aveskamp & Verkley, L. rubefaciens (Togliani) Gruyter, Aveskamp & Verkley, L. sclerotioides (Sacc.) Gruyter, Aveskamp & Verkley, L. sydowii (Boerema, Kesteren & Loer.) Gruyter, Aveskamp & Verkley, L. veronicae (Hollós) Gruyter, Aveskamp & Verkley, Medicopsis romeroi (Borelli) Gruyter, Verkley & Crous, Nigrograna mackinnonii (Borelli) Gruyter, Verkley & Crous, Paraconiothyrium flavescens (Gruyter, Noordel. & Boerema) Verkley & Gruyter, Paracon. fuckelii (Sacc.) Verkley & Gruyter, Paracon. fusco-maculans (Sacc.) Verkley & Gruyter, Paracon. lini (Pass.) Verkley & Gruyter, Paracon. tiliae (F. Rudolphi) Verkley & Gruyter, Paraleptosphaeria dryadis (Johanson) Gruyter, Aveskamp & Verkley, Paralept. macrospora (Thüm.) Gruyter, Aveskamp & Verkley, Paralept. nitschkei (Rehm ex G. Winter) Gruyter, Aveskamp & Verkley, Paralept. orobanches (Schweinitz: Fr.) Gruyter, Aveskamp & Verkley, Paralept. praetermissa (P. Karst.) Gruyter, Aveskamp & Verkley, Plenodomus agnitus (Desm.) Gruyter, Aveskamp & Verkley, Plen. biglobosus (Shoemaker & H. Brun) Gruyter, Aveskamp & Verkley, Plen. chrysanthemi (Zachos, Constantinou & Panag.) Gruyter, Aveskamp & Verkley, Plen

  7. Obituary: Janet Akyüz Mattei, 1943-2004

    Science.gov (United States)

    Williams, Thomas R.; Willson, Lee Anne

    2004-12-01

    As director of the American Association of Variable Star Observers for thirty years, Janet Mattei led the organization through a series of major improvements and in the process, helped and influenced amateur and professional astronomers around the world. Having successfully tackled many challenges, however, Janet lost her battle with acute myelogenous leukemia on 22 March 2004. One of five children of Bella and Baruk Akyüz, Janet was born on 2 January 1943 in Bodrum, Turkey and received her pre-collegiate education there. She attended Brandeis University from 1962 until 1965 on a full Wein Scholarship, earning a BA in General Science. After eighteen months of supervising a cardiopulmonary laboratory, in 1967 she returned to Turkey to teach physics and mathematics in a high school, and then entered graduate school at Turkey's Ege University. Janet learned of the summer scholarships available at the Maria Mitchell Observatory on Nantucket, and applied to observatory director Dorrit Hoffleit for the opportunity to come back to the United States and learn about variable stars. That summer (1969) she learned to love variable stars, became acquainted with the AAVSO, and met her future husband, Michael Mattei. In 1970, after she earned her master's degree in astronomy at Ege University, Janet entered the University of Virginia where she earned a second master's degree in 1972 with a thesis on T Tauri stars. After receiving her degree in Virginia, Janet married Mike Mattei and became an assistant to Margaret Mayall at AAVSO headquarters. When Mayall decided to retire in 1973, the AAVSO Council asked Janet to assume the helm as director of the association. With such a sudden advance in her responsibilities, Janet had to rapidly learn the management side of running the organization as well as keep up with the day-to-day scientific activities - responding to requests for data, recording observations as pencil-points on paper charts, and predicting future maxima of long

  8. The Climate-G Portal: a Grid Enabled Scientifc Gateway for Climate Change

    Science.gov (United States)

    Fiore, Sandro; Negro, Alessandro; Aloisio, Giovanni

    2010-05-01

    Grid portals are web gateways aiming at concealing the underlying infrastructure through a pervasive, transparent, user-friendly, ubiquitous and seamless access to heterogeneous and geographical spread resources (i.e. storage, computational facilities, services, sensors, network, databases). Definitively they provide an enhanced problem-solving environment able to deal with modern, large scale scientific and engineering problems. Scientific gateways are able to introduce a revolution in the way scientists and researchers organize and carry out their activities. Access to distributed resources, complex workflow capabilities, and community-oriented functionalities are just some of the features that can be provided by such a web-based environment. In the context of the EGEE NA4 Earth Science Cluster, Climate-G is a distributed testbed focusing on climate change research topics. The Euro-Mediterranean Center for Climate Change (CMCC) is actively participating in the testbed providing the scientific gateway (Climate-G Portal) to access to the entire infrastructure. The Climate-G Portal has to face important and critical challenges as well as has to satisfy and address key requirements. In the following, the most relevant ones are presented and discussed. Transparency: the portal has to provide a transparent access to the underlying infrastructure preventing users from dealing with low level details and the complexity of a distributed grid environment. Security: users must be authenticated and authorized on the portal to access and exploit portal functionalities. A wide set of roles is needed to clearly assign the proper one to each user. The access to the computational grid must be completely secured, since the target infrastructure to run jobs is a production grid environment. A security infrastructure (based on X509v3 digital certificates) is strongly needed. Pervasivity and ubiquity: the access to the system must be pervasive and ubiquitous. This is easily true due

  9. Madde Etkisi Şüphesi Altındaki Sürücülerde Tükürük Analizi

    Directory of Open Access Journals (Sweden)

    Serap Annette Akgür

    2006-04-01

    Full Text Available İlaç/maddelerin trafik kazalarına etkisi bir çok yayında gösterilmiştir. Son on yılda, yol üzerinde uygulanabilen madde testleriyle ilişkili birçok gelişme meydana gelmiştir. Kötüye kullanımı olan maddelerin etkisi altındaki sürücünün saptanmasına yönelik hızlı, güvenilir ve kolay uygulanabilir yol üzeri testler, ter, idrar ve tükürük gibi alternatif matriksler üzerine odaklanmıştır. Avrupa birliği ROSITA projesi (Road Side Testing Assessment, kannabinoid, opiat, amfetamin ve türevlerinin yüksek prevalans gösterdiği birçok yasadışı maddenin, farklı biyolojik matrikslerde bulunduğunu göstermiştir. Ege Üniversitesi ve İzmir Emniyet müdürlüğü’nün işbirliği ve Cozart firmasının katkılarıyla bu proje gerçekleştirilmiştir. Bu projenin amacı, bu yol üzeri uygulanan testin kullana-bilirliği ve uygulanabilirliği yanında polis tarafından karşılaşabilecek problemleri saptamaktır. Bu çalışmada trafik kontrol noktalarında randomize olarak seçilen 25 araç sürücüsünde solunum havasında etilalkol analizi yanında tükürükte kötüye kullanımı olan maddelerin analizi için Cozart Bioscience Ra-piscan 5’li tükürük panel testi (kannabinoid, amfetamin, kokain, opiat ve benzodiazepin uygulanmıştır. Kişiler gönüllü onam formunu imzalayarak çalışmaya katılmışlardır. Doğrulama GC-MS’le yapılmış; oral sıvıda MDA 65 ng/mL ve MDMA 180 ng/mL olarak bulunmuştur. Anahtar kelimeler: Madde etkisi altında taşıt sürme, yol üzeri madde testi, tükürük

  10. Primary care physician perceptions on the diagnosis and management of chronic obstructive pulmonary disease in diverse regions of the world

    Directory of Open Access Journals (Sweden)

    Aisanov Z

    2012-04-01

    Full Text Available Zaurbek Aisanov1,*, Chunxue Bai2,*, Otto Bauerle3,*, Federico D Colodenco4,*, Charles Feldman5,6,*, Shu Hashimoto7,*, Jose Jardim8,*, Christopher KW Lai9,*, Rafael Laniado-Laborin10,*, Gilbert Nadeau11,*, Abdullah Sayiner12,*, Jae Jeong Shim13,*, Ying Huang Tsai14,*, Richard D Walters11,*, Grant Waterer15,* 1Pulmonology Research Institute, Moscow, Russia; 2Department of Pulmonary Medicine, Fudan University, Shanghai, People's Republic of China; 3Centro Médico de las Américas, Mérida, Yucatán, Mexico; 4Hospital de Rehabilitación Respiratoria "María Ferrer," Buenos Aires, Argentina; 5Department of Internal Medicine, Charlotte Maxeke Johannesburg Hospital, Johannesburg, South Africa; 6Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; 7Division of Respiratory Medicine, Department of Internal Medicine, Nihon University School of Medicine, Tokyo, Japan; 8Federal University of São Paulo, São Paulo, Brazil; 9Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, People's Republic of China; 10Faculty of Medicine, Universidad Autónoma de Baja California, Tijuana, Baja California, Mexico; 11Medical Affairs, GlaxoSmithKline, Brentford, UK; 12Department of Chest Diseases, Ege University Medical School, Izmir, Turkey; 13Department of Pulmonology, Guro Hospital, Korea University Medical Center, Seoul, South Korea; 14Department of Respiratory Care Medicine, Chang Gung Memorial Hospital, Chia-Yi, Taiwan; 15School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia*ICON group (International COPD Network, listed in alphabetical orderAbstract: Chronic obstructive pulmonary disease (COPD is a multicomponent disorder that leads to substantial disability, impaired quality of life, and increased mortality. Although the majority of COPD patients are first diagnosed and treated in primary care practices, there is comparatively little

  11. Clinical factors and comorbidities affecting the cost of hospital-treated COPD

    Directory of Open Access Journals (Sweden)

    Deniz S

    2016-12-01

    Full Text Available Sami Deniz,1 Aysun Şengül,2 Yusuf Aydemir,3 Jülide Çeldir Emre,4 Mustafa Hikmet Özhan5 1Clinics of Chest Diseases, Dr Suat Seren Chest Diseases and Thoracic Surgery Education and Research Hospital, İzmir, 2Clinics of Chest Diseases, Kocaeli Derince Research and Education Hospital, Kocaeli, 3Department of Chest Diseases, Sakarya University Faculty of Medicine, Sakarya, 4Clinics of Chest Diseases, Turgutlu State Hospital, Manisa, 5Department of Chest Diseases, Faculty of Medicine, Ege University İzmir, Turkey Purpose: We aimed to assess the effects of comorbidities on COPD costs and to investigate the relationship between comorbidities and clinical variables.Patients and methods: All patients hospitalized with a diagnosis of COPD exacerbation between January 1, 2014, and December 31, 2014, at all state hospitals of Aydin province, a city located in the western part of Turkey, were included in this study. The costs examined in the study pertained to medications, laboratory tests, hospital stays, and other treatment-related factors, such as consumption of materials, doctor visits, and consultation fees.Results: A total of 3,095 patients with 5,237 exacerbations (mean age, 71.9±10.5 years; 2,434 males and 661 females were evaluated. For 880 of the patients (28.9%, or 3,852 of the exacerbations (73.1%, at least one comorbid disease was recorded. The mean cost of each exacerbation was $808.5±1,586, including $325.1±879.9 (40.7% for hospital stays, $223.1±1,300.9 (27.6% for medications, $46.3±49.6 (0.9% for laboratory expenditures, and $214±1,068 (26.5% for other treatment-related factors, such as consumption of materials, doctor visits, and consultation fees. The cost of each exacerbation was $1,014.9 in patients with at least one comorbidity, whereas it was $233.6 in patients without comorbidity (P<0.001. Age >65 years, female gender, hospitalization in an intensive care unit, invasive or noninvasive mechanical ventilation, and a

  12. GreenView and GreenLand Applications Development on SEE-GRID Infrastructure

    Science.gov (United States)

    Mihon, Danut; Bacu, Victor; Gorgan, Dorian; Mészáros, Róbert; Gelybó, Györgyi; Stefanut, Teodor

    2010-05-01

    Eastern Europe) regions. On the other hand, GreenLand is used for generating maps for different vegetation indexes (e.g. NDVI, EVI, SAVI, GEMI) based on Landsat satellite images. Both applications are using interpolation and random value generation algorithms, but also specific formulas for computing vegetation index values. The GreenView and GreenLand applications have been experimented over the SEE-GRID infrastructure and the performance evaluation is reported in [6]. The improvement of the execution time (obtained through a better parallelization of jobs), the extension of geographical areas to other parts of the Earth, and new user interaction techniques on spatial data and large set of satellite images are the goals of the future work. References [1] GreenView application on Wiki, http://wiki.egee-see.org/index.php/GreenView [2] SEE-GRID-SCI Project, http://www.see-grid-sci.eu/ [3] Gorgan D., Stefanut T., Bâcu V., Mihon D., Grid based Environment Application Development Methodology, SCICOM, 7th International Conference on "Large-Scale Scientific Computations", 4-8 June, 2009, Sozopol, Bulgaria, (To be published by Springer), (2009). [4] Gorgan D., Bacu V., Stefanut T., Rodila D., Mihon D., Grid based Satellite Image Processing Platform for Earth Observation Applications Development. IDAACS'2009 - IEEE Fifth International Workshop on "Intelligent Data Acquisition and Advanced Computing Systems: Technology and Applications", 21-23 September, Cosenza, Italy, IEEE Published in Computer Press, 247-252 (2009). [5] Mihon D., Bacu V., Stefanut T., Gorgan D., "Grid Based Environment Application Development - GreenView Application". ICCP2009 - IEEE 5th International Conference on Intelligent Computer Communication and Processing, 27 Aug, 2009 Cluj-Napoca. Published by IEEE Computer Press, pp. 275-282 (2009). [6] Danut Mihon, Victor Bacu, Dorian Gorgan, Róbert Mészáros, Györgyi Gelybó, Teodor Stefanut, Practical Considerations on the GreenView Application Development and

  13. Grid-based Meteorological and Crisis Applications

    Science.gov (United States)

    Hluchy, Ladislav; Bartok, Juraj; Tran, Viet; Lucny, Andrej; Gazak, Martin

    2010-05-01

    forecast model is a subject of the parameterization and parameter optimization before its real deployment. The parameter optimization requires tens of evaluations of the parameterized model accuracy and each evaluation of the model parameters requires re-running of the hundreds of meteorological situations collected over the years and comparison of the model output with the observed data. The architecture and inherent heterogeneity of both examples and their computational complexity and their interfaces to other systems and services make them well suited for decomposition into a set of web and grid services. Such decomposition has been performed within several projects we participated or participate in cooperation with academic sphere, namely int.eu.grid (dispersion model deployed as a pilot application to an interactive grid), SEMCO-WS (semantic composition of the web and grid services), DMM (development of a significant meteorological phenomena prediction system based on the data mining), VEGA 2009-2011 and EGEE III. We present useful and practical applications of technologies of high performance computing. The use of grid technology provides access to much higher computation power not only for modeling and simulation, but also for the model parameterization and validation. This results in the model parameters optimization and more accurate simulation outputs. Having taken into account that the simulations are used for the aviation, road traffic and crisis management, even small improvement in accuracy of predictions may result in significant improvement of safety as well as cost reduction. We found grid computing useful for our applications. We are satisfied with this technology and our experience encourages us to extend its use. Within an ongoing project (DMM) we plan to include processing of satellite images which extends our requirement on computation very rapidly. We believe that thanks to grid computing we are able to handle the job almost in real time.

  14. Field studies on long term ecosystem consequences of ionising radiation and chemical pollutants (EANOR Project)

    Energy Technology Data Exchange (ETDEWEB)

    Oughton, D. [Centre for Environmental Radioactivity - CERAD (Norway); Evseeva, T. [Institute of Biology RAS (Russian Federation); Erenturk, S. [Istanbul Technical University (Turkey)

    2014-07-01

    -barcoding, invertebrate DNA barcoding, DNA methylation, and other molecular endpoints is ongoing, together with studies of possible adaptation of plants, invertebrates and microorganisms. Preliminary results show significant differences in diversity for many species between contaminated and reference sites. However, more research is needed to draw conclusions about the cause of such observations. Nevertheless, by combining a through site characterisation and exposure assessment with a variety of ecologically relevant biomarker and endpoint measurements, the data produced should be a valuable contribution to international activities looking at the impacts of chronic exposure of ionising radiation on non-human species. Project participants: Elena Belykh, Anna Kaneva, Boris Kondratenok, Alla Kolesnikova, Alexey Kurdin, Tatinana Majstrenko, Taskayeva Anastasia Oleshya Vakhrusheva, Illa Velegzhaninov, Vladimir Zainullin (IoB, Komi Republic, Russia); S. Haciyakupoglu (Istanbul Technical University, Turkey); Rahime Oral, Sabriye Yusan, Filiz Gur Filiz (Ege University, Turkey); Murat Belivermis, Onder Kilic (Istanbul University, Turkey); Fatma Kocbas (Celal Bayar University, Turkey); Mustafa Akiner, (Rize University, Turkey); Claire Coutris, Erik Joner (Bioforsk, Norway); Turid Hertel-Aas, Emmanuel Lapied, Yevgeniya Tomkiv, Brit Salbu, Lindis Skipperud (Centre for Environmental Radioactivity, UMB, Norway). Document available in abstract form only. (authors)

  15. Categorization of COPD patients in Turkey via GOLD 2013 strategy document: ALPHABET study

    Directory of Open Access Journals (Sweden)

    Gunen H

    2015-11-01

    Full Text Available Hakan Gunen,1 Mehmet Yilmaz,2 Oguz Aktas,1 Pinar Ergun,3 Mediha Gonenc Ortakoylu,4 Atike Demir,5 Pelin Cetinkaya,6 Alev Gurgun,7 Muge Otlu,8 Aykut Cilli,9 Ufuk Yilmaz,5 Nurdan Kokturk,10 Ipek Candemir,3 Halil Ibrahim Yakar,1 Idilhan Ar,11 Aylin Konya111Department of Chest Diseases, Sureyyapasa Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey; 2Department of Chest Diseases, Safranbolu State Hospital, Karabuk, Turkey; 3Department of Chest Diseases, Ataturk Chest Diseases and Thoracic Surgery Training and Research Hospital, Ankara, Turkey; 4Department of Chest Diseases, Yedikule Chest Diseases and Thoracic Surgery Training and Research Hospital, Istanbul, Turkey; 5Department of Chest Diseases, Dr Suat Seren Chest Diseases and Thoracic Surgery Training and Research Hospital, Izmir, Turkey; 6Department of Chest Diseases, Cukurova Dr Askim Tufekci State Hospital, Adana, Turkey; 7Department of Chest Diseases, Ege University Faculty of Medicine, Izmir, Turkey; 8Department of Chest Diseases, Bingol State Hospital, Bingol, Turkey; 9Department of Chest Diseases, Akdeniz University, Faculty of Medicine, Antalya, Turkey; 10Department of Chest Diseases, Gazi University Faculty of Medicine, Ankara, Turkey; 11Medical Department, Novartis Pharmaceuticals, Istanbul, TurkeyObjective: To determine distribution of COPD assessment categories and physicians’ adherence to Global Initiative for Chronic Obstructive Lung Disease (GOLD 2013 strategy in Turkish COPD patients.Methods: A total of 1,610 COPD patients (mean [standard deviation] age: 62.6 [9.9] years, 85.7% were males were included in this multicenter, non-interventional, cross-sectional study. Patients were categorized via GOLD 2013 strategy document. Consistency between reported and re-classified GOLD categories, and measures used for symptom evaluation and exacerbation was analyzed.Results: Overall, 41.1% of patients were assigned to GOLD A, while 13.2% were assigned to

  16. İzmir İç Körfezi İhtiyoplankton Kompozisyonu.

    Directory of Open Access Journals (Sweden)

    Dilek Türker Çakır

    2015-12-01

    Full Text Available Ege Denizi’ndeki en önemli balıkçılık alanlarından biri olan İzmir Körfezi’nde geçmiş yıllarda meydana gelen kirliliğin neden olduğu biyolojik çeşitlilikte olumsuz yönde değişmeler olmuştur. 2001 büyük kanal projesinin devreye girmesi ile meydana gelmiş olumsuz değişimler tersine dönmeye başlamıştır. Bu değişimler üzerine çok çeşitli araştırmalar yapılmış ve halen yapılmaktadır. Bu çalışma “Büyük Kanal Projesinin Aktif Hale Geçirilmesinin İzmir Körfezi Sularında Alt Besinsel Seviyeler Üzerine Etkileri (YDABAG 102Y116” adlı proje kapsamında yürütülmüş olup İzmir İç Körfezi’nde yaşayan balıkların yumurta ve larvalarının tür çeşitliliği, bolluğu, dağılımları ve mortaliteleri araştırılmıştır. İhtiyoplankton örnekleri 19.12.2002-26.12.2003 tarihleri arasında 15’er günlük periyotlarda 3 istasyondan toplanmış olup ağız çapı 51 cm, uzunluğu 2.5 m ve 200 μm göz açıklığında UNESCO-WP2 model plankton kepçesi ile vertikal olarak gerçekleştirilmiştir. Çalışma süresince toplam 9613.8 adet/m2 yumurta, 568.4 adet/m2 larva tespit edilmiştir. Sardina pilchardus (Walbaum, 1792, Engraulis encrasicolus (Linnaeus, 1758, Diplodus sp., Symphodus melops (Linnaeus, 1758, Callionymus pusillus Delaroche, 1809, Callionymus sp., Gobius niger Linnaeus, 1758, Gobius paganellus Linnaeus, 1758, Arnoglossus sp., Buglossidium luteum (Risso, 1810 türlerinin yumurta ve/veya larvaları tayin edilmiştir. E. encrasicolus türüne ait yumurta, prelarva ve postlarva dominanttır. Bu türün yumurtalarında %12.05 oranında mortalite belirlenmiştir

  17. European grid services for global earth science

    Science.gov (United States)

    Brewer, S.; Sipos, G.

    2012-04-01

    This presentation will provide an overview of the distributed computing services that the European Grid Infrastructure (EGI) offers to the Earth Sciences community and also explain the processes whereby Earth Science users can engage with the infrastructure. One of the main overarching goals for EGI over the coming year is to diversify its user-base. EGI therefore - through the National Grid Initiatives (NGIs) that provide the bulk of resources that make up the infrastructure - offers a number of routes whereby users, either individually or as communities, can make use of its services. At one level there are two approaches to working with EGI: either users can make use of existing resources and contribute to their evolution and configuration; or alternatively they can work with EGI, and hence the NGIs, to incorporate their own resources into the infrastructure to take advantage of EGI's monitoring, networking and managing services. Adopting this approach does not imply a loss of ownership of the resources. Both of these approaches are entirely applicable to the Earth Sciences community. The former because researchers within this field have been involved with EGI (and previously EGEE) as a Heavy User Community and the latter because they have very specific needs, such as incorporating HPC services into their workflows, and these will require multi-skilled interventions to fully provide such services. In addition to the technical support services that EGI has been offering for the last year or so - the applications database, the training marketplace and the Virtual Organisation services - there now exists a dynamic short-term project framework that can be utilised to establish and operate services for Earth Science users. During this talk we will present a summary of various on-going projects that will be of interest to Earth Science users with the intention that suggestions for future projects will emerge from the subsequent discussions: • The Federated Cloud Task

  18. MONSOONS MUDE AND GOLD MUSONLAR GEMİ VE ALTIN

    Directory of Open Access Journals (Sweden)

    Paul LUNDE

    2009-12-01

    Full Text Available The “global economy” of the Middle Ages was created by linking the Indian Ocean trading networks with those of the Mediterranean Sea and its African and European hinterlands. These products, together with ceramics, textiles and sugar provided from Egypt and Syria, reached European markets almost exclusively through the Italian maritime republics of Amalfi, Pisa, Genoa and Venice. Especially the direction of the monsoon winds in the Indian Ocean and the course of the Venice trade ships were at the same direction. Thereby, Venice trade ships set out toward the end of August and made their way slowly through the Adriatic and the Aegean to Cyprus and Alexandria, timing their arrival there to coincide with the availability of monsoon-borne and by this way the products which are ned carried through Europe. İt is important to emphasize this subject that North Europe economy depends on this Monsoons where they became at Indian Ocean. As a maritime republic dedicated itself to the international trade, Venice was an anomaly in a feudal Europe that measured wealth by land, not money. Therefor this idea were encouraging their believing about ending the monopoly of the Muslim trade at the Indian Ocean. Ortaçağın global ekonomisini Hint Okyanusu ticaret hattı ile Akdeniz, Afrika ve Avrupa Hinterlantları arasındaki ticaret bağlantısı teşkil ediyordu. Avrupa ekonomisindeki gelişmelere paralel olarak Batı dünyasının gereksinim duyduğu ve Mısır ile Suriye’den tedarik edilen şeker, tekstil, seramik gibi ürünler Amalfi, Pisa, Ceneviz ve Venedik gibi İtalyan Cumhuriyetleri aracılığıyla Avrupa pazarlarına taşınmaktaydı. Özellikle Hint Okyanusu üzerindeki muson rüzgârlarının yönleriyle Venedik ticaret gemilerinin rotaları aynı doğrultudaydı. Bu suretle Ağustos ayının sonuna doğru İtalya’dan ayrılan gemiler, Adriyatik, Ege ve Kıbrıs rotasından İskenderiye’ye ulaştığı esnada musonlarla kar

  19. Müfredata eklenen bir dersin ikinci sınıf tıp öğrencilerinin kadına yönelik şiddetle ilgili bilgi ve tutumlarına etkilerinin değerlendirilmesi

    Directory of Open Access Journals (Sweden)

    Hediye Aslı Davas Aksan

    2011-12-01

    Full Text Available Amaç: Bu araştırmanın amacı “kadına yönelik şiddete müdahalede sağlık çalışanlarının rolü” uygulama dersini alan Ege Üniversitesi Tıp Fakültesi ikinci sınıf öğrencilerinin ders öncesi ve sonrasındaki bilgi düzeyleri ve tutumlarını ölçmek ve toplumsal cinsiyet rolleri hakkındaki görüşlerini tanımlamaktır. Yöntem: Tıp Fakültesi ikinci sınıfa 334 kişi kayıtlıdır. Kapsayıcılık  %85,6’dır. Ankette kadına yönelik şiddet tanımlarıyla ilgili on soru, hekimin bu konudaki rolüyle ilgili sekiz soru ve toplumsal cinsiyet rolleriyle ilgili 20 soru ve öğrencilerin sosyo demografik özelliklerini sorgulayan sekiz soru yer almaktadır. Bilgi soruları 10 puan üzerinden, profesyonel tutum ve toplumsal cinsiyet rollerine ilişkin sorular ise üçlü Likert ölçeğiyle değerlendirilmiştir. Daha yüksek puan alan öğrenci daha olumlu tutuma sahip kabul edilmiştir. Bulgular: Araştırma grubunun %39,9’u kadındır. % 41,9’u Fen lisesi, %36,5’i Anadolu lisesi ve %%10,8’i özel lise mezunudur. %45,1 Ege Bölgesi doğumludur. Öğrencilerin %15,2’si ailesinde şiddete tanık olduğunu belirtmiştir. Ön test bilgi puan ortalaması 6,8±1,8 iken son test sonuçları 9,1±1,4 (t=-22,923, p=0,001olarak saptanmıştır. Ders öncesi profesyonel tutum toplam puanı ortalaması 19,7±2,4, ders sonrası da 21,1±2,3 olmuştur(t=9,877 p=0,001. Toplumsal cinsiyet rolleri ön test toplam puanı 47,2±7,4 son test toplam puanı ise 48,4±6,4 olarak saptanmıştır(t=3,577, p=0,001. Hem bilgi hem de profesyonel tutum ve toplumsal cinsiyet rolleriyle ilgili ön-test puan ortalamaları erkeklerin, doğduğu bölge İç Anadolu, Doğu Anadolu ve Güneydoğu Anadolu olanların, anne eğitimi ortaokul ve altı düzeyinde olanların daha düşüktür. Sonuç: Bu araştırmada, uzun erimdeki etkiler değerlendirilememiş olsa da, Tıp fakültesi ikinci sınıf müfredatına eklenen bu dersin,

  20. Future Events

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    1996-10-01

    Full Text Available I.\tThe Changing Health Care Enviroment: Issues for the Future, March 7, 1997, Nashville, Tennessee. For further information: American Society of Law, Medicine & Ethics, 765 Commonwealth Avenue, 16th Floor, Boston, Massachusetts 02215 USA. Tel: 617 262 4990, Fax: 617 437 7596, Email: aslme@bu.edu. II.\tII. Adli Bilimler Sempozyumu,Balistik, 4-5 Nisan 1997, İzmir. İletişim: Doç.Dr.İ.Hamit Hancı, Ege Üniversitesi Tıp Fakültesi, Adli Tıp Anabilim Dalı, 35100 Bornova İZMİR. Tel: 0232 388 2157, 0232 388 1920/3256 III.\tGender Studies, Date commencement: 5 March 1997-24 April 1997, Days and times: Wednesdays 18.00-20.00. 1. Women's rights, 2. Serhia & Women, 3. Women & Law, 4. Refuge Women, 5. Domestic violence & Women, 6. Working life & Women, 7. Women & Union, 8. Politics & Women. For further information: Aysel İşçi & Dr.Laurence Raw, The British Council, Kırlangıç sok. No: 9, 06700 GOP ANKARA. Tel: 0312 468 6192 Fax: 0312 427 6182. IV.\tForensic Science Society Spring Meeting, Suspicious Death?, 11-13 April 1997, Leeds, United Kingdom. Details from Anne Holds- worth, 18A Mount Parade, Harrogate, North Yorkshire, UNITEN KINGDOM HGI IBX. An- ne@fscisoc.demon.co.uk. V.\tForensic Medicine and Drugs: Clinical and Scientific Aspects, 24-25 April 1997, Stakis Hydro, Dunblane, Scotland. Contact Dr DG Williams, Dept of Biochemistry, District General Hospital, Sunderland, UNITED KINGDOM. Tel: 0191 565 6256 ext 42800. VI.\tIV. Sosyal Psikiyatri Sempozyumu, 7-9 Mayıs 1997, Adana. Yazışma adresi: Prof.Dr.Yunus Emre Evlice, Çukurova Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, Balcalı 01330 ADANA. Tel: 0322 338 6857. VII.\tIII. Kadın Çalışmaları Toplantısı, 17-19 Mayıs 1997, Adana. İletişim: Çukurova Üniversitesi Kadın Sorunları Araştırma ve Uygulama Merkezi, Bakalı ADANA. VIII.\tThe 5th International Family Violence Research Conference, Family Research Laboratory, 29 June-2 July 1997, Durham United Kingdom

  1. Bilimsel Toplantı Duyuruları

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    1996-10-01

    Full Text Available I.\tThe Changing Health Care Enviroment: Issues for the Future, March 7, 1997, Nashville, Tennessee. For further information: American Society of Law, Medicine & Ethics, 765 Commonwealth Avenue, 16th Floor, Boston, Massachusetts 02215 USA. Tel: 617 262 4990, Fax: 617 437 7596, Email: aslme@bu.edu. II.\tII. Adli Bilimler Sempozyumu,Balistik, 4-5 Nisan 1997, İzmir. İletişim: Doç.Dr.İ.Hamit Hancı, Ege Üniversitesi Tıp Fakültesi, Adli Tıp Anabilim Dalı, 35100 Bornova İZMİR. Tel: 0232 388 2157, 0232 388 1920/3256 III.\tGender Studies, Date commencement: 5 March 1997-24 April 1997, Days and times: Wednesdays 18.00-20.00. 1. Women's rights, 2. Serhia & Women, 3. Women & Law, 4. Refuge Women, 5. Domestic violence & Women, 6. Working life & Women, 7. Women & Union, 8. Politics & Women. For further information: Aysel İşçi & Dr.Laurence Raw, The British Council, Kırlangıç sok. No: 9, 06700 GOP ANKARA. Tel: 0312 468 6192 Fax: 0312 427 6182. IV.\tForensic Science Society Spring Meeting, Suspicious Death?, 11-13 April 1997, Leeds, United Kingdom. Details from Anne Holds- worth, 18A Mount Parade, Harrogate, North Yorkshire, UNITEN KINGDOM HGI IBX. An- ne@fscisoc.demon.co.uk. V.\tForensic Medicine and Drugs: Clinical and Scientific Aspects, 24-25 April 1997, Stakis Hydro, Dunblane, Scotland. Contact Dr DG Williams, Dept of Biochemistry, District General Hospital, Sunderland, UNITED KINGDOM. Tel: 0191 565 6256 ext 42800. VI.\tIV. Sosyal Psikiyatri Sempozyumu, 7-9 Mayıs 1997, Adana. Yazışma adresi: Prof.Dr.Yunus Emre Evlice, Çukurova Üniversitesi Tıp Fakültesi, Psikiyatri Anabilim Dalı, Balcalı 01330 ADANA. Tel: 0322 338 6857. VII.\tIII. Kadın Çalışmaları Toplantısı, 17-19 Mayıs 1997, Adana. İletişim: Çukurova Üniversitesi Kadın Sorunları Araştırma ve Uygulama Merkezi, Bakalı ADANA. VIII.\tThe 5th International Family Violence Research Conference, Family Research Laboratory, 29 June-2 July 1997, Durham United Kingdom

  2. III Adli Bilimler Kongresi - Posterler

    Directory of Open Access Journals (Sweden)

    Adli Tıp Uzmanları Derneği ATUD

    2000-08-01

    . Yaralanmanın anatomik lokalizasyonuna karşın önemli bir patolojik bulgu saptanmadı. Bu olguyu, boynu kat eden bir yaralanmanın ciddi komplikasyonlara ya da ölüme yol açmamasının nadir görülmesi nedeniyle sunduk. Anahtar kelimeler: Boyun yaralanması, ateşli silah yaralanması. ADLİ OTOPSİLERİN ATEROSKLEROZ YÖNÜNDEN DEĞERLENDİRİLMESİ Erdem ÖZKARA* AH YEMİŞCİGİL*. ÖZET Bu çalışma ani ölümlerin oluşmasında önemli bir etken olan aterosklerozun yaşa ve cinse bağlı değişimini araştırmak amacıyla adli otopsi olgularında yapılmıştır. Adli Tıp Kummu Başkanlığı İstanbul ve İzmir Morg İhtisas Daire Başkanlıklarında 1995-1996 yıllarında yapılan otopsilerde, çürümenin ilerlemediği olgulardan rastlantısal olarak seçilen 100 tanesinde üç önemli damar (aorta abdominalis, a. cerebri media ve a. coronaria sinistra izole edilerek toplam 300 damarda horizontal kesitlerde aterosklerotik oluşumlar ve damar lümenindeki daralma yüzdeleri araştırılarak ortaya çıkan veriler Mann-Whitney U testi ile değerlendirildi. Çalışmamızda aterosklerozun erkeklerde, özellikle de 40 yaş ve üstünde daha belirgin olmak üzere, kadınlara göre anlamlı olarak artmış olduğunu saptadık. Aterosklerotik oluşumların eskiden myokard infarktüsü geçirmiş olanlarda diğerlerine göre çok ileri boyutta olduğu görüldü. Kadın ve erkeklerde yaşla birlikte hastalığın da ilerlediği, 40 yaş ve üzerinde 18-39 yaş grubuna göre lezyonlarm daha artmış olduğu saptandı. İncelediğimiz damarlar arasında yapılan değerlendirmede Aorta abdominalis deki lezyonlarm göreceli olarak daha ileri düzeyde olduğu görüldü. Anahtar Kelimeler: Ateroskleroz, adli otopsi, ani ölüm. İZMİR’DE 1996 YILI BOYUNCA YAPILAN OTOPSİLERDE ZEHİRLENME OLGULARININ DEĞERLENDİRİLMESİ Serap A. AKGÜR*, Pembe ÖZTÜRK**, Süheyla ERTÜRK***, Fatih ŞEN****, Beyhan EGE*****. ÖZET Fatal zehirlenmeye voi açan toksik maddeler çok

  3. Türkiye’deki Üniversitelerin Türk Dili ve Edebiyatı Bölümü 4. Sınıf Öğrencilerinin Türkoloji Kavramına İlişkin Algıları Perception Of The Turkology Concept Among Fourth Grade Students Of The Departments Of Turkish Language And Literature In The Unıversities In Turkey

    Directory of Open Access Journals (Sweden)

    Serdar YAVUZ

    2013-03-01

    sında İslam, Doğu ve dil araştırmaları ekseninde gelişen Türkoloji, günümüzde Türk’e ait ne varsa inceleyen bir bilim hâline gelmiştir. Özellikle ilk dönemlerde Türkologların dil araştırmalarına yoğunlaşması, onun bakış açısı ve yöntemlerini kullanması nedeniyle Türkolojinin sadece kavramsal olarak Türk diliyle özdeşleşmesine neden olmuştur. Bu çalışmaların etkisiyle Türkoloji, Türk dili gibi algılanmıştır. Bu çalışmanın amacı, Türkiye’deki üniversitelerin Türk Dili ve Edebiyatı Bölümü 4. sınıf öğrencilerinin “Türkoloji” kavramına ilişkin algılarını, geliştirdikleri metaforlar aracılığıyla ortaya çıkarmaktır. Araştırmanın çalışma grubunu, Türkiye Cumhuriyeti sınırlarında bulunan yedi coğrafi bölge (Marmara Bölgesi, Ege Bölgesi, Akdeniz Bölgesi, İç Anadolu Bölgesi, Karadeniz Bölgesi, Doğu Anadolu bölgesi ve Güneydoğu Anadolu Bölgesi ve bu bölgeler içerisinde bulunan 7 üniversitenin Türk Dili ve Edebiyatı Bölümü 4. sınıfında okuyan 320 öğrenci oluşturmaktadır. Araştırmanın verileri her öğrencinin “Türkoloji… gibidir, çünkü …” cümlesini tamamlamasıyla elde edilmiştir. Verilerin analiz edilmesinde ise toplanan verileri açıklayabilecek kavramlara ve ilişkilere ulaşılabilecek olan içerik analizi tekniği kullanılmıştır. Araştırmanın sonunda Türk Dili ve Edebiyatı Bölümü 4. sınıf öğrencilerinin % 87,7’sinin Türkoloji kavramına ilişkin olumlu, % 11,4’ünün olumsuz ve % 0,9’unun ise hem olumlu hem de olumsuz bir algıya sahip oldukları tespit edilmiştir. Olumlu algıya sahip öğrenciler; değer katma, disiplin, inceleme alanı; olumsuz algıya sahip öğrenciler bilimsel eksiklik, iş kaygısı, olumsuz tutum; hem olumlu hem de olumsuz algıya sahip öğrenciler ise hem olumlu hem de olumsuz tutum kodu altında toplanan metaforlar geliştirmiştir.

  4. Arnavutluk’taki Osmanlı Dönemi Mimarisinde İstanbul Tasvirli Duvar Resimleri İstanbul Depiction Mural Paintings in Architecture of Ottoman Period in Albania

    Directory of Open Access Journals (Sweden)

    Metin UÇAR

    2013-09-01

    öre değerlendirilmiştir. Ayrıca, resimlerdeki üslup özellikleri ve dönemin etkileri irdelenerek, teknik ve düzenleme açısından analiz edilerek, Anadolu’daki çağdaşlarıyla karşılaştırılmaya çalışılmıştır.Osmanlı İmparatorluğu’nda XVIII. yüzyıl ortalarından itibaren başkent İstanbul ve Anadolu’daki dini ve sivil mimaride uygulanmaya başlayan duvar resimleri Arnavutluk’taki yapıların duvar yüzeylerinde de görülmeye başlar. Günümüzde çok az sayıdaki yapıda örnekleri kalmış olan duvar resimleri, yapıların iç ve dış duvar yüzeylerindeki madalyonlar, panolar, kuşaklar ve çerçevelerin içlerinde yer almaktadır. Resimlerde ele alınan konular, ağırlıklı olarak natürmort, manzara ve kent tasvirlerinden oluşmaktadır. Konu olarak seçilen kent tasvirleri içerisinde İstanbul, dönemin başkenti olması nedeniyle öncelikli bir yer teşkil eder. Genellikle hayali olarak ele alınan İstanbul tasvirleri, Akçahisar (Kruje Toptaniler Konağı, Berat Bekarlar Camii, Berat Cako (Xhaxhi Qako Evi, ve Görice (Korçe Mirahor İlyas Bey Camii duvar yüzeylerinde yer almaktadır.Konusu İstanbul olan ve günümüzde farklı ülke toprakları içerisinde kalan duvar resimleri, bölgedeki yerel sanatçılar tarafından yapılmış olmasına rağmen özellikle Ege ve Marmara bölgesinde bulunan çağdaşları ile teknik, üslup ve düzen açısından büyük benzerlikler gösterir.

  5. gProcess and ESIP Platforms for Satellite Imagery Processing over the Grid

    Science.gov (United States)

    Bacu, Victor; Gorgan, Dorian; Rodila, Denisa; Pop, Florin; Neagu, Gabriel; Petcu, Dana

    2010-05-01

    The Environment oriented Satellite Data Processing Platform (ESIP) is developed through the SEE-GRID-SCI (SEE-GRID eInfrastructure for regional eScience) co-funded by the European Commission through FP7 [1]. The gProcess Platform [2] is a set of tools and services supporting the development and the execution over the Grid of the workflow based processing, and particularly the satelite imagery processing. The ESIP [3], [4] is build on top of the gProcess platform by adding a set of satellite image processing software modules and meteorological algorithms. The satellite images can reveal and supply important information on earth surface parameters, climate data, pollution level, weather conditions that can be used in different research areas. Generally, the processing algorithms of the satellite images can be decomposed in a set of modules that forms a graph representation of the processing workflow. Two types of workflows can be defined in the gProcess platform: abstract workflow (PDG - Process Description Graph), in which the user defines conceptually the algorithm, and instantiated workflow (iPDG - instantiated PDG), which is the mapping of the PDG pattern on particular satellite image and meteorological data [5]. The gProcess platform allows the definition of complex workflows by combining data resources, operators, services and sub-graphs. The gProcess platform is developed for the gLite middleware that is available in EGEE and SEE-GRID infrastructures [6]. gProcess exposes the specific functionality through web services [7]. The Editor Web Service retrieves information on available resources that are used to develop complex workflows (available operators, sub-graphs, services, supported resources, etc.). The Manager Web Service deals with resources management (uploading new resources such as workflows, operators, services, data, etc.) and in addition retrieves information on workflows. The Executor Web Service manages the execution of the instantiated workflows

  6. Grid enablement of OpenGeospatial Web Services: the G-OWS Working Group

    Science.gov (United States)

    Mazzetti, Paolo

    2010-05-01

    integration on existing solutions. More specifically, the Open Geospatial Consortium (OGC) Web Services (OWS) specifications play a fundamental role in geospatial information sharing (e.g. in INSPIRE Implementing Rules, GEOSS architecture, GMES Services, etc.). On the Grid side, the gLite middleware, developed in the European EGEE (Enabling Grids for E-sciencE) Projects, is widely spread in Europe and beyond, proving its high scalability and it is one of the middleware chosen for the future European Grid Infrastructure (EGI) initiative. Therefore the convergence between OWS and gLite technologies would be desirable for a seamless access to the Grid capabilities through OWS-compliant systems. Anyway, to achieve this harmonization there are some obstacles to overcome. Firstly, a semantics mismatch must be addressed: gLite handle low-level (e.g. close to the machine) concepts like "file", "data", "instruments", "job", etc., while geo-information services handle higher-level (closer to the human) concepts like "coverage", "observation", "measurement", "model", etc. Secondly, an architectural mismatch must be addressed: OWS implements a Web Service-Oriented-Architecture which is stateless, synchronous and with no embedded security (which is demanded to other specs), while gLite implements the Grid paradigm in an architecture which is stateful, asynchronous (even not fully event-based) and with strong embedded security (based on the VO paradigm). In recent years many initiatives and projects have worked out possible approaches for implementing Grid-enabled OWSs. Just to mention some: (i) in 2007 the OGC has signed a Memorandum of Understanding with the Open Grid Forum, "a community of users, developers, and vendors leading the global standardization effort for grid computing."; (ii) the OGC identified "WPS Profiles - Conflation; and Grid processing" as one of the tasks in the Geo Processing Workflow theme of the OWS Phase 6 (OWS-6); (iii) several national, European and

  7. Balıkesir’de Serbest Cumhuriyet Fırkası’nınteşkilatlanması ve Belediye Seçimleri (1930 Liberal Rebuplican Party Orgazation In Balıkesir And Local Elections (1930

    Directory of Open Access Journals (Sweden)

    Ömer KARAKAŞ

    2013-07-01

    öneminde Terakki Perver Cumhuriyet Fırkası’ndan sonra kurulan ve ikinci demokrasi deneyimi olan Serbest Cumuriyet Fırkası’nın Balıkesir vilayetindeki teşkilatlanması ve 1930’da yapılan belediye seçimleri ele alınmıştır.Öncelikle, SCF’nin teşkilatlanma öncesinde ve teşkilatlandığı sırada Balıkesir vilayetinin sosyo- ekonomik yapısı değerlendirilmiştir. Bahsi geçen yıllarda, zeytin, tütün gibi ihracat ürünleri ile geçimini sağlayan Balıkesir halkının zor durumda olduğu görülmektedir. Özellikle köylü, üzerine düşen vergileri ödemekte zorlanmakta, Ziraat Bankasından tarımsal faaliyetlerini sürdürmekte gerekli olan krediyi alamamaktadır. Ayrıca, vilayet halkınının devlet memurlarından da bazı şikayetlerinin olduğu anlaşılmaktadır. Memurların görevlerindeki bazı suistimalleri mahalli basın kaynaklarında yer almıştır. Hükümetin başta sıtma olmak üzere bulaşıcı hastalıklarla mücadelede yetersiz kaldığı görülmektedir. Söz konusu şikayet konularının SCF’nin Balıkesir’ de siyasi teveccüh görmesinde önemli bir etken olduğu söylenebilir.SCF lideri Fethi Okyar, çıktığı Ege gezisinde Balıkesir’de bir miting düzenlemiştir. Balıkesir halkının mitinge olan yoğun katılımı SCF’nin bu ildeki siyasi ağırlığını göstermesi bakımından anlamlıdır. SCF lideri konuşmasında, ağırlıklı olarak yukarıda dile getirilen halkın hükümetten şikayetçi olduğu konuları ele almnıştır.SCF Balıkesir’de hızlı bir şekilde teşkilatlanmıştır. Sadece şehir merkezinde değil aynı zamanda ilçelerde ve köylerde de teşkilatlanma çalışmaları yaptığı anlaşılmaktadır. Bu çalışmalar sırasında CHF’nin muhalefeti hatta yer yer engelemeleri ile de karşılamıştır.Diğer Batı Anadolu vilayetlerinde olduğu gibi Balıkesir’de de 1930 belediye seçimlerinde yolsuzluk ve usulsüzlükler olduğu vakıa’dır. CHF lilerle SCF üyeleri arasında ya

  8. News and Announcements

    Science.gov (United States)

    1999-06-01

    : July 15, 1999 Postdoctoral Program in Environmental Chemistry: February 26, 1999 Further information may be obtained from The Camille and Henry Dreyfus Foundation, Inc., 555 Madison Avenue, Suite 1305, New York, NY 10022; phone: 212/753-1760; email: admin@dreyfus.org; WWW: http://www.dreyfus.org/ Research Corporation Cottrell College Science Awards: May 15 and November 15 Cottrell Scholars: First regular business day in September Partners in Science: December 1 (the final opportunity for this program is summer 1999) Research Opportunity Awards: May 1 and October 1 Research Innovation Awards: May 1 Further information may be obtained from Research Corporation, 101 North Wilmot Road, Suite 250, Tucson, AZ 85711-3332; phone: 520/571-1111; fax: 520/571-1119; email: awards@rescorp.org; www: http://www.rescorp.org 1999 American Oil Chemists' Society Awards The American Oil Chemists' Society announce the following awards, to be presented at their annual meeting in Orlando, FL, May 1999. Supelco/Nicholas Pelick Research Award Andrew Sinclair, Royal Melbourne Institute of Technology-University of Australia Stephen S. Chang Award Edwin N. Frankel, University of California at Davis 16th BCCE Coming Up The Web site for the 16th Biennial Conference on Chemical Education is up and running at http://www. umich.edu/ bcce. The Biennial Conference will be held from July 30 through August 3, 2000, at the University of Michigan, Ann Arbor. Organizers of symposia and workshops and proposers of papers are invited to submit their ideas via the Web or in writing to either the Program Chair, Brian Coppola; phone: 734/764-7329; email: bcoppola@umich.edu, or to the Workshop Coordinator, Evelyn Jackson; phone: 517/355-9715 ext 204; email: ejackson@argus.cem.msu.edu. For general information please contact Seyhan Ege; phone: 734/764-7340; email: snege@umich.edu. Student Participation at ACS Meetings The ACS Division of Chemical Health and Safety (CHAS) announces a new program to encourage student

  9. Grid-based platform for training in Earth Observation

    Science.gov (United States)

    Petcu, Dana; Zaharie, Daniela; Panica, Silviu; Frincu, Marc; Neagul, Marian; Gorgan, Dorian; Stefanut, Teodor

    2010-05-01

    found in [4]. The Workload Management System (WMS) provides two types of resource managers. The first one will be based on Condor HTC and use Condor as a job manager for task dispatching and working nodes (for development purposes) while the second one will use GT4 GRAM (for production purposes). The WMS main component, the Grid Task Dispatcher (GTD), is responsible for the interaction with other internal services as the composition engine in order to facilitate access to the processing platform. Its main responsibilities are to receive tasks from the workflow engine or directly from user interface, to use a task description language (the ClassAd meta language in case of Condor HTC) for job units, to submit and check the status of jobs inside the workload management system and to retrieve job logs for debugging purposes. More details can be found in [4]. A particular component of the platform is eGLE, the eLearning environment. It provides the functionalities necessary to create the visual appearance of the lessons through the usage of visual containers like tools, patterns and templates. The teacher uses the platform for testing the already created lessons, as well as for developing new lesson resources, such as new images and workflows describing graph-based processing. The students execute the lessons or describe and experiment with new workflows or different data. The eGLE database includes several workflow-based lesson descriptions, teaching materials and lesson resources, selected satellite and spatial data. More details can be found in [5]. A first training event of using the platform was organized in September 2009 during 11th SYNASC symposium (links to the demos, testing interface, and exercises are available on project site [1]). The eGLE component was presented at 4th GPC conference in May 2009. Moreover, the functionality of the platform will be presented as demo in April 2010 at 5th EGEE User forum. References: [1] GiSHEO consortium, Project site, http

  10. Esamojo laiko formantas -st- išvestiniuose lietuvių kalbos veiksmažodžiuose

    Directory of Open Access Journals (Sweden)

    Jurgis Pakerys

    2011-12-01

    Full Text Available Lithuanian secondary verbs based on present stems in ‑staSummaryLithuanian has a number of deverbative formations which are clearly based on present stems, cf.: ded‑ẽklė ‘good layer (about hens’ : dẽd‑a ‘lays’, dúod‑ingas ‘open‑handed, generous’, duod‑imas ‘giving’ : dúod‑a ‘gives’, verd‑ẽnė ‘spring’ : vérd‑a ‘boils’, es‑ìmas ‘being’ : es‑ù ‘I am’, ẽs‑ti ‘it is’, tek‑ìmas ‘rising (of the sun’ : tẽk‑a ‘flows, runs; rises (the sun’ (beside tekė́ti, ‑ė́jo and tekė́jimas, lim̃p‑alas ‘sticky material’ : li‑m̃‑p‑a ‘sticks’, skrand‑nùs ‘good flyer’ : skre‑ñ‑d‑a ‘flies’, kánk‑inti(s ‘to give enough, to satisfy’ : (paka‑ñ‑k‑a ‘suffices’, té‑n‑k‑inti ‘to satisfy’ : (užte‑ñ‑k‑a ‘suffices’, trunk‑imas ‘delaying’ : tru‑ñ‑k‑a ‘lasts, delays’, etc. (Būga 1959, 446; Urbutis 1978, 191, 197; Ambrazas 1993, 21‑25.This paper presents examples of Lithuanian secondary verbs based on present stems in ‑sta, cf. pýkst‑auti ‘to be angry’ : pỹkst‑a ‘is angry’. These formations represent a rare (archaic? derivational process and they can be used to support the hypothesis of the deverbative origin of suffix ‑styti (Latvian ‑stīt. The proponents of this hypothesis believe that present stems in ‑sta provided bases for some formations in ‑yti (‑o, ‑ė which were later resegmented and gave rise to new suffix ‑styti (‑sto, ‑stė, cf.: lankst‑ýti : liñkst‑a → lank‑stýti : leñk‑ti (Ul’janov 1888, 210; Leumann 1942, 125; Vaillant 1966, 364; Smoczyński 1987, 203. On the other hand, the data presented in this paper still do not exclude the possibility of denominal origin of ‑styti (Leskien 1884, 443; Johanson 1893, 502; Endzelin 1922, 641; Skardžius 1943, 538; Stang 1942, 149; cf. Jasanoff 2003, 141.All material was excerpted from

  11. News and Announcements

    Science.gov (United States)

    1999-07-01

    University of Michigan in Ann Arbor, is up and running at http://www.umich.edu/ bcce. Organizers of symposia and workshops as well as proposers of papers are invited to submit their ideas over the Web or in writing to the Program Chair, Brian Coppola; phone: 734/764-7329; email: bcoppola@umich.edu, or to the Workshop Coordinator, Evelyn Jackson; phone: 517/355-9715 ext 204; email: ejackson@argus.cem.msu.edu. For general information please contact Seyhan Ege, phone: 734/764-7340, email: snege@umich.edu. ChemCareers Debuts on ChemCenter The ACS ChemCenter website has recently launched a moderated career forum where chemists, chemical engineers, scientists in related fields, students, and other interested persons pose their questions related to career development in the chemical sciences. At the site you can hear what your peers think about preparing for, launching, maintaining, and advancing a career in chemistry. You can bring questions, share experiences, or offer advice. The forum is moderated by ACS career consultants who offer their expert opinions as a part of the discussion. The address is http://www.chemcenter.org. Click on the "discussions" hypertext link under "Discover Chemistry." Green Chemistry The closing date for grant funding from the EPA/NSF Technologies for a Sustainable Environment Solicitation is July 26, 1999. For specific grant information, visit the Web site www.nsf.gov/pubs/1999/nsf99108/nsf99108.txt. For general grant information about green chemistry, go to www.epa.gov/greenchemistry, es.epa.gov/ncerqa/grants, and www.nsf.gov; phone: 202/260-2659. Grad Resources Hotline A national crisis hotline sponsored by Grad Resources was set up effective April 1999. Graduate students who face overwhelming stress or despair may call 1/877-GRAD-HLP, toll-free, 24 hours a day, every day, to speak anonymously with a counselor specially trained in graduate issues. Grad Resources is a non-profit organization serving graduate students. For further references and

  12. From Editor vol 11, No.4

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2010-10-01

    determine the characteristics in effective and successful online and/or face-to-face instructors. Survey information was divided into five categories and provided very different information. Although this was a limited study, it provided valuable information that instructors cannot view teaching both online and face to face classes as one-fits all type approach. Two books and a conference are reviewed in this issue. The first book was about Learning And Instructional Technologies For The 21st Century Leslie Moller, Jason Bond Huett and Douglas M. Harvey (Eds. and reviewed by Reviewed by Reviewed by Alev ATES, Ege University, Izmir, TURKEY. She summarized that the book helps closing a gap in the instructional technology research for the 21st century with many implications from case studies and experimental studies with students and teachers. A Conference o n An International Symposium On The New Vista Education System Of Open, Distance And E-Learning is reviewed by A. Q. M. Bazlur RASHID, Bangladesh Agricultural University, BANGLADESH International Symposium on Open, Distance and E-Learning held at Discovery Kartika Plaza Hotel at Bali, Indonesia by hosted by ICT Centre for Education, Ministry of National Education of the Republic Indonesia was a unique forum for scientific expositions on the progress of development and implementation on the fast-growing ICT global network, especially in the field of open, distance and e-learning. The second book is about “Educational Technology In Practice Research and Practical Case Studies from the Field” edited by Edited by Wanjira KINUTHIA and Steward MARSHALL and reviewed by Ozden SAHIN-IZMIRLI, Computer Education and Instructional Technology, Eskisehir Osmangazi University, Eskisehir, TURKEY. The editors stated that when technological tools are used to establish an effective and productive study process in education, the concept of learning technology is used instead of educational technology. The editors of the book considers the

  13. Türk Patolojisinde Bir Okul Prof Dr Talia Bali Aykan 13 Ağustos 1918 - 31 Ağustos 2003

    Directory of Open Access Journals (Sweden)

    Aydın Sav

    2003-12-01

    Full Text Available Aydın SAV Ege Üniversitesi mezunu bir doktor olarak, öğrenciliğimde bana patoloji dalını sevdirmiş hocalarımı ardımda bırakıp, bu alanda uzmanlık eğitimimi yapmak üzere birçok kapıyı çaldıktan soma ilk defa 1980 yılında “Talia Hoca”yla karşılaştım. Bu ilk mülakatımızda, beni dinleyip merakla bu mesleği neden seçtiğimi sormasıyla “mikroskobun içinden bir mikrofon sarkıtıp hücrelerle röportaj yapmak istediğim için” dediğimi hatırlıyorum. Hoca bana dönüp “İstanbul'da bir kalacak yerin var mı?” sorusuna olumlu yanıt verdikten sonraa, ertesi günü gönüllü olarak Cerrahpaşa Tıp Fakültesi Patoloji Anabilim'de göreve başladım. Çok kısa bir süre sonraa hocamın asistan kadrosu açmasıyla sınavı geçip resmi asistanlık statümü kazandım. O günden 31 Ağustos 2003'e kadar tam tamına yirmi üç yıl geçti. Uzmanlık eğitimimi izleyen yıllarda da kesintisiz bir işbirliğiyle birlikte sonunda dostluğa dönüşen yolculuğumuz halen bütün canllılığı ve verimiyle devam ediyordu. Ta ki... 31 Ağustos 2003 Pazar günü Çanakkale, Küçükkuyu beldesinin bir tatil tesisinde denizde yüzerken bu yıldız aramızdan ayrıldı. Türkiye Cumhuriyetine kanat geren bir bilimci, “hoca”, dost ve “insan” Prof. Dr. Talia Bali Aykan. 1918 yılında İstanbul'un Beylerbeyi'nde başlayan ve yaşamının tamamım düşünmeye, araştırmaya, eğitime, anlamaya ve anlatmaya adamış olan hocam seksenbeş yıllık bir ömrün ardından, binlerce paylaşılmış anı, eser ve belge bırakarak ayrıldı aramızdan. Hocamı tanıdıkça, daha çok hayret, daha çok hayranlık ve hepsinden önemlisi daha çok saygı duydum. Başlarda bilimsel kişiliği ve yaklaşımları dikkatimi çekmişti. Giderek de mesleğini ve dünyayı makro planda ve son derece ciddiyet ve cesaretle ele alarak değerlendiren kişiliği. Tüm yaşamını, ülkeme nasıl hizmet ederim? Yapılan bu iş

  14. from Editorial

    Directory of Open Access Journals (Sweden)

    Ugur dEMİRAY

    2011-07-01

    Full Text Available Greetings Dear readers of TOJDE,TOJDE is appeared on your screen now as Volume 12, Number: 3. In this issue it is published 5 notes for Editor, 16 articles, 1 book review. And this time, 33 authors from 10 different countries are placed. These published articles are from Bangldesh, Ghana, India, Iran, Malaysia, Nigeria, Pakistan, Saudi Arabia, Turkey and USA.The first Notes for editor arrived from USA, written by Kevin YEE and Jace HARGIS. They focused on Web site does not offer a way on its main page to restrict searches only to Creative Commons licenses. They mentioned that while Google Images does many functions extremely well, this search Web site does not offer a way on its main page to restrict searches only to Creative Commons licenses. There is a setting on the Advanced Search page for “reuse” licenses (not precisely the same concept as Creative Commons, provided users remember to check this before performing any search. Before restricting the setting, a search for the term “tiger” yielded 48 million results. After restricting Google Images just to “reuse” results, only 14,000 webpages were identified for the term “tiger”.The second notes for editor is titled as “Self-Efficacy Beliefs, Achievement Motivation and Gender as Related to Educational Software Development” which is written by Alev ATES from Ege University, Faculty of Education, Computer Education and Instructional Technologies Department, Bornova, Izmir, TURKEY. The aims of her to investigate preservice computer teachers’ self-efficacy beliefs and achievement motivation levels for educational software development before and after the “Educational Software Design, Development and Evaluation (ESDDE” course.“The Effects of The Interactive White Board Usage On The Students’ Learning Level And An Application in The Financial Markets Courses” is the third paper for “Notes for Editor” section of TOJDE’s in this issue. It has written by Yasemin

  15. News and Announcements

    Science.gov (United States)

    1999-04-01

    of Michigan in Ann Arbor from July 30-August 3, 2000. Information about the conference is posted on the World Wide Web at www.umich.edu/ bcce or may be obtained from the following persons. General Chair: Seyhan Ege; phone: 734/764-7340; fax: 734/647-4865; email: snege@umich.edu. Program Chair: Brian Coppola; phone: 734/764-7329; email: bcoppola@umich.edu. Workshop Coordinator: Evelyn Jackson; phone: 517/355-9715 ext.204; email: ejackson@argus.cem.msu.edu. Massachusetts State Science Fair The 50th Massachusetts State Science Fair will take place April 30 and May 1, 1999. To celebrate the anniversary, we plan to hold a gathering of all Fair alumni/alumnae. Thus we are trying to contact all persons who have ever exhibited science projects at this state-wide high school Fair that has been held each year at the Massachusetts Institute of Technology. Anyone who has exhibited a science project at the State Fair should send their name, present address, the name of the school they were attending when participating in the Fair, and the date(s) they exhibited to the Fair office: Massachusetts State Science Fair, 45 Howlands Lane, Kingston, MA 02364-1637. If there are questions, contact Micheline M. Mathews-Roth, M.D., the chair of the alumni/alumnae committee, by phone at 617/525-2249. Call for Proposals, EDUCAUSE '99 Celebrating New Beginnings is the title of the EDUCAUSE '99 annual conference, to be held October 26-29, 1999, in Long Beach, California. The conference will be a celebration of new beginnings and a forum to shape and define our agenda for the 21st century. This is a new association focused on enabling information technology to shape the nature of teaching, learning, scholarship, research, and institutional management and invite you to participate. At this first EDUCAUSE annual conference, we will identify the opportunities, address the issues, and celebrate the potential for transforming education through information technology; we will bring together information

  16. Climate forcing growth rates: doubling down on our Faustian bargain

    Science.gov (United States)

    Hansen, James; Kharecha, Pushker; Sato, Makiko

    2013-03-01

    Laboratory, US Department of Energy) doi:10.3334/CDIAC/00001_V2012 BP (British Petroleum) 2012 Statistical Review of World Energy 2012 (www.bp.com/sectionbodycopy.do?categoryId=7500&contentId=7068481) Chavez F P et al 1999 Biological and chemical response of the Equatorial Pacific Ocean to the 1997-1998 El Nino Science 286 2126-31 Cipolla C L 2009 Modeling production and evaluating fracture performance in unconventional gas reservoirs J. Petrol. Technol. 61 84-90 Earth System Research Laboratory (ESRL) 2012 Trends in Atmospheric Carbon Dioxide (www.esrl.noaa.gov/gmd/ccgg/trends/) Energy Information Administration (EIA) 2011 International Energy Outlook (www.eia.gov/forecasts/ieo/pdf/0484(2011).pdf, accessed Sep. 2011) Galloway J N, Cowling E B, Seitzinger S P and Socowlow R H 2002 Reactive nitrogen: too much of a good thing? AMBIO 31 60-3 German Advisory Council on Global Change (GAC) 2011 World in Transition—A Social Contract for Sustainability (www.wbgu.de/en/flagship-reports/fr-2011-a-social-contract/, accessed Oct. 2011) Global Energy Assessment (GEA) 2012 Toward a Sustainable Future ed T B Johanson et al (Luxemburg: International Institute for Applied Systems Analysis) p 118 Gloor M, Sarmiento J L and Gruber N 2010 What can be learned about carbon cycle climate feedbacks from the CO2 airborne fraction? Atmos. Chem. Phys. 10 7739-51 Gruber N and Galloway J N 2008 An Earth-system perspective of the global nitrogen cycle Nature 451 293-6 Gu L et al 2003 Response of a deciduous forest to the Mount Pinatubo eruption: enhanced photosynthesis Science 299 2035-8 Hansen J 2003 Can we defuse the global warming time bomb? Natural Science posted 1 Aug 2003 Hansen J 2009 Storms of My Grandchildren: The Truth About the Coming Climate Catastrophe and Our Last Chance to Save Humanity (New York: Bloomsbury) p 304 Hansen J E and Lacis A A 1990 Sun and dust versus greenhouse gases: an assessment of their relative roles in global climate change Nature 346 713-9 Hansen J, Ruedy R, Sato M

  17. From the Editor

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2009-10-01

    environmentally aware individuals. It is taught that television is a good and the best media and educational tool in an environmental education to a targeted group that has fairly high ratio of television watching habits contrary to reading habits. So, what can be the properties of an environmental education program?Four books are reviewed in this issue. The first one is about belogs to me and my colleague Dr. N. Serdar Sever. The book is titled as THE CHALLENGES FOR MARKETING DISTANCE EDUCATION IN ONLINE ENVIRONMENTAn Integrated Approach reviewed by Reviewed by Natalija LEPKOVA, from Lithuania. The book is purposed of role of marketing and to understand trends in the field and customer needs in a global marketplace. In this case the customers are students and they could be called as a “kings” of the market. This is a challenge with online learning because the field is in a constant state of development. Marketing online education programs is becoming more of a necessity as global competition increases. To be on time and in a right place­­­-this is the target of distance learning marketing. The second one about “Economics of Distance and Online Learning Theory, Practice and Research” By William BRAMBLE & Santosh PANDA. The book points to directions for the further research and development in this area, and will promote further understanding and critical reflection on the part of administrators, practitioners and researchers of distance education. The experiences and perspectives in distance education in the US are balanced with those in other areas of the world.The third book review reviewdd by Alev ATES, Ege University, Izmir, TURKEY, on “The Handbook of Blended Learning: Global Perspectives, Local Designs”. She mentioned concluded that, “The Handbook of Blended Learning: Global Perspectives, Local Designs” is a quite comprehensive reference with the contributions of prominent experts in instructional technology and a helpful handbook for those who wish to

  18. From Editor vol 11, No.3

    Directory of Open Access Journals (Sweden)

    Ugur Demiray

    2010-07-01

    taught by the same teacher, in which there were 79 2nd, 3rd and 4th grade university students, in central city of Diyarbakır in Turkey. An experimental research design including the electrostatic achievement test (EAT, the electrostatic concept test (ECT, physics attitude scale (PAS and self-efficacy perception scale (SEPS was applied at the beginning and at the end of the research as pre-test and post-test. After the treatment, general achievement in EAT increased (P<0.05, but not all of subgroup. Difference between pre-test and post-test both knowledge and application levels of cognitive domain was found significant (P<0.05, but not in comprehension level. This result showed that using CAI7E in teaching electrostatic topic was very effective for physics student teachers already learned this topic in several physics course to reach knowledge and application levels of cognitive domain. Two books are reviewed in this issue. The first one is about THE BLENDED LEARNING BOOK: Best Practices, Proven Methodologies and Lessons Learned written by Josh Bersin and reviewed by Reviewed by Reviewed by Alev ATES, Ege University, Izmir, TURKEY The book starts with the introduction section explaining Internet based learning adventure and e-learning evolution. He defines Blended Learning (BL as the combination of different training “media” (technologies, activities, and types of events to create an optimum training program for a specific audience. Afterwards, Bersin presents us history of BL by asking “How did we get here?”.The second one is about “THE PERFECT ONLINE COURSE: Best Practices for Designing and Teaching” edited by Edited By Anymir Orellana, Terry L. Hudgins, & Michael Simonson and reviewed by Cengiz Hakan AYDIN, Anadolu University, Eskisehir TURKEY. The book, entitled as The Perfect Online Course: Best Practices for Designing and Teaching is also trying to establish a list of standards about how to design and implement an effective online course. The main goal

  19. Analysis of Maths Learning Activities Developed By Pre-service Teachers in Terms of the Components of Content, Purpose, Application Methods [Öğretmen Adaylarının Geliştirdikleri Matematik Öğrenme Etkinliklerinin Seçilen Konu, Amaç, Uygulama Şekli Bileşenleri Açısından Analizi

    Directory of Open Access Journals (Sweden)

    Çağla Toprak

    2014-04-01

    alışmalarla ortaya konulmuştur (Hazır-Bıkmaz, 2006. Öğretmenler gerek öğretim materyallerinin hazırlanması gerekse uygulanması aşamasında oldukça kritik bir role sahiptir (Stein ve Smith, 1998b; Swan, 2007. Mevcut öğretim programları özelde matematik ve geometri öğretim programları incelendiğinde en önemli öğrenme materyalinin etkinlikler olduğu görülmektedir (Bozkurt, 2012. Hatta mevcut öğretim programlarını etkinlik temelli olarak nitelendirmek mümkündür (İlköğretim Programları İçeriğinin Branşlara Göre İncelenmesi Çalıştayı Raporu, 2010; Epö, 2005. Bu sebeple öğrenme etkinliklerinin ne olduğu, hangi özellikleri barındırması gerektiği, nasıl tasarlanacağı ve uygulanacağı üzerinde durulması gereken konulardır (Uğurel ve ark., 2010. Bu noktada etkinliklerin geliştirilme sürecinde öğretmen adaylarının becerilerini artırmaya yönelik yürütülen çalışmamız Ege Bölgesi’nde ki bir devlet üniversitesinin, Ortaöğretim Matematik Öğretmenliği bölümünde 4. sınıfta öğrenim gören 19’u kız 8’i erkek 27 öğretmen adayı ile gerçekleştirilmiştir. Öğretmen adaylarının bir dizi uygulama sonucunda kendilerine verilen şablona uygun geliştirdikleri etkinlik örnekleri seçilen konu-tasarlanma amacı ve uygulama biçimine göre doküman analizine tabi tutulmuştur. Yapılan incelemenin sonucunda öğretmen adaylarının etkinlik tasarımında daha çok matematik öğretim programındaki konuları ele aldığı bu konuların farklı sınıf seviyelerinden olduğu görülmüştür. Amaç bileşeni adı altında yapılan inceleme sonucunda ise geliştirilen etkinliklerin en çok bir öğrenmeyi gerçekleştirme amacını taşıdığı bunu ise öğrenilen kavram(ları pekiştirmenin izlediği görülmüştür. Öğretmen adaylarının geliştirdikleri etkinlikleri uygulamada en fazla küçük (işbirlikli grup çalışmasını benimsedikleri ortaya konulmuştur.

  20. News & Announcements

    Science.gov (United States)

    1999-09-01

    for travel awards for post-doctoral, graduate, and undergraduate women to make their first research presentation at a national meeting sponsored by Eli Lilly & Co. For more information and an application form, contact your department chair; http://www.tamug.tamu.edu/ascwcc; or Cheryl Brown, ACS, 1155 16th Street, NW, Washington, DC 20036; phone: 800/227-5558 ext. 6022; email c_brown@acs.org. The deadline for receipt of applications for meetings between January 1 and June 30, 2000, is October 15, 1999; for meetings between July 1 and December 31, 2000, the deadline is March 15, 2000. Call for Symposia, Papers, Workshops: 16th BCCE The 16th Biennial Conference on Chemical Education will be held July 30­August 3, 2000, at the University of Michigan in Ann Arbor. The conference Web site at http://www.umich.edu/ bcce is ready to accept proposals for symposia, papers, posters, and workshops. Or proposals may be submitted in writing to the Program Chair, Brian Coppola, phone: 734/764-7329; email: bcoppola@umich.edu. The deadline for submission of proposals for symposia and workshops is December 13, 1999; the deadline for submission of abstracts of papers and posters is February 4, 2000. For general information contact Seyhan Ege, phone: 734/764-7340; email: snege@umich.edu. 16th IUPAC Conference on Chemical Thermodynamics 16th IUPAC Conference on Chemical Thermodynamics (concurrent with 55th Calorimetry Conference and 10th Symposium on Thermodynamics of Nuclear Materials) August 6­11, 2000 Halifax, Nova Scotia, Canada This conference will cover research topics in all areas of thermodynamics. In addition, there will be a special poster session for papers on two aspects of thermodynamics education: lecture demonstrations and undergraduate laboratory experiments. Come and join us for lobster and learn what is new and exciting in thermodynamics. To be on the email list for this meeting, send a message to: ICCT@IS.DAL.CA. For further details, consult the conference Web site