WorldWideScience

Sample records for effects general

  1. Generalized EMV-Effect Algebras

    Science.gov (United States)

    Borzooei, R. A.; Dvurečenskij, A.; Sharafi, A. H.

    2018-04-01

    Recently in Dvurečenskij and Zahiri (2017), new algebraic structures, called EMV-algebras which generalize both MV-algebras and generalized Boolean algebras, were introduced. We present equivalent conditions for EMV-algebras. In addition, we define a partial algebraic structure, called a generalized EMV-effect algebra, which is close to generalized MV-effect algebras. Finally, we show that every generalized EMV-effect algebra is either an MV-effect algebra or can be embedded into an MV-effect algebra as a maximal ideal.

  2. Intervals in Generalized Effect Algebras and their Sub-generalized Effect Algebras

    Directory of Open Access Journals (Sweden)

    Zdenka Riečanová

    2013-01-01

    Full Text Available We consider subsets G of a generalized effect algebra E with 0∈G and such that every interval [0, q]G = [0, q]E ∩ G of G (q ∈ G , q ≠ 0 is a sub-effect algebra of the effect algebra [0, q]E. We give a condition on E and G under which every such G is a sub-generalized effect algebra of E.

  3. The Geometric Nonlinear Generalized Brazier Effect

    DEFF Research Database (Denmark)

    Nikolajsen, Jan Ánike; Lauridsen, Peter Riddersholm; Damkilde, Lars

    2016-01-01

    that the generalized Brazier effect is a local effect not influencing the overall mechanical behavior of the structure significantly. The offset is a nonlinear geometric beam-type Finite Element calculation, which takes into account the large displacements and rotations. The beam-type model defines the stresses which...... mainly are in the direction of the beam axis. The generalized Brazier effect is calculated as a linear load case based on these stresses....

  4. Questions concerning the generalized Hartman effect

    International Nuclear Information System (INIS)

    Kudaka, Shoju; Matsumoto, Shuichi

    2011-01-01

    With reference to a particle tunneling through two successive barriers, it seems to have been generally accepted that the tunneling time does not depend on the separation distance between the barriers. This phenomenon has been called the generalized Hartman effect. In this Letter, we point out a lack of mathematical rigor in the reasoning by which this effect was deduced about ten years ago. A mathematically rigorous treatment shows us that the tunneling time does indeed depend on the length of the free space between the barriers. -- Highlights: → The total tunneling time of a particle tunneling through two barriers is discussed. → We focus on the generalized Hartman effect. → A lack of mathematical rigor is in the reasoning by which this effect was deduced. → We show that the tunneling time depends on the distance between the two barriers.

  5. Misleading presumption of a generalized Hartman effect

    International Nuclear Information System (INIS)

    Simanjuntak, Herbert P.; Pereyra, Pedro

    2007-07-01

    We analyze different examples to show that the so-called generalized Hartman effect is an erroneous presumption. The results obtained for electron tunneling and transmission of electromagnetic waves through superlattices and Bragg gratings show clearly the resonant character of the phase time behavior where a generalized Hartman effect is expected. A reinterpretation of the experimental results in double Bragg gratings is proposed. (author)

  6. A general equilibrium view of global rebound effects

    International Nuclear Information System (INIS)

    Wei Taoyuan

    2010-01-01

    How do energy efficiency gains affect energy consumption? The effects are generally called 'rebound effects' in the literature. Previous studies have extensively focused on only part of the global economy to study rebound effects, e.g. energy consumption by households, one industry, or one country. However, since the global economy is highly connected among countries, these studies may lead to misleading conclusions if the rebound effects in the rest of the economy are significant. Recently Saunders (2008) analyzes the demand side by taking the global economy as a whole. Wei (2007) also provides a general analysis by using Cobb-Douglas production functions for the global economy. The present article expands Wei (2007) general analysis to explore the rebound effects from an economist's viewpoint by taking the global economy as a whole and applying general forms of production functions. The analysis provides new insights related to rebound effects: we highlight the role of energy supply as a determinant of rebound. We show that the substitution between energy resources and other productive resources is more relevant to long term rebound. We predict that long term rebound may be lower than short term rebound. And we also discover that super-conservation can happen in both the short term and the long term.

  7. Lagrangian formulation of the general relativistic Poynting-Robertson effect

    Science.gov (United States)

    De Falco, Vittorio; Battista, Emmanuele; Falanga, Maurizio

    2018-04-01

    We propose the Lagrangian formulation for describing the motion of a test particle in a general relativistic, stationary, and axially symmetric spacetime. The test particle is also affected by a radiation field, modeled as a coherent flux of photons traveling along the null geodesics of the background spacetime, including the general relativistic Poynting-Robertson effect. The innovative part of this work is to prove the existence of the potential linked to the dissipative action caused by the Poynting-Robertson effect in general relativity through the help of an integrating factor, depending on the energy of the system. Generally, such kinds of inverse problems involving dissipative effects might not admit a Lagrangian formulation; especially, in general relativity, there are no examples of such attempts in the literature so far. We reduce this general relativistic Lagrangian formulation to the classic case in the weak-field limit. This approach facilitates further studies in improving the treatment of the radiation field, and it contains, for example, some implications for a deeper comprehension of the gravitational waves.

  8. Effects of electronic communication in general practice

    NARCIS (Netherlands)

    van der Kam, WJ; Moorman, PW; Koppejan-Mulder, MJ

    2000-01-01

    Objective: To obtain insight into the effects of electronic communication on GPs by studying those publications in literature describing the effects of structured electronic clinical communication in general practice. Methods: We retrieved all publications in the English language indexed in MEDLINE

  9. Prototype Effect and the Persuasiveness of Generalizations.

    Science.gov (United States)

    Dahlman, Christian; Sarwar, Farhan; Bååth, Rasmus; Wahlberg, Lena; Sikström, Sverker

    An argument that makes use of a generalization activates the prototype for the category used in the generalization. We conducted two experiments that investigated how the activation of the prototype affects the persuasiveness of the argument. The results of the experiments suggest that the features of the prototype overshadow and partly overwrite the actual facts of the case. The case is, to some extent, judged as if it had the features of the prototype instead of the features it actually has. This prototype effect increases the persuasiveness of the argument in situations where the audience finds the judgment more warranted for the prototype than for the actual case (positive prototype effect), but decreases persuasiveness in situations where the audience finds the judgment less warranted for the prototype than for the actual case (negative prototype effect).

  10. The Faraday effect revisited: General theory

    DEFF Research Database (Denmark)

    Cornean, Horia Decebal; Nenciu, Gheorghe; Pedersen, Thomas Garm

    This paper is the first in a series revisiting the Faraday effect, or more generally, the theory of electronic quantum transport/optical response in bulk media in the presence of a constant magnetic field. The independent electron approximation is assumed. For free electrons, the transverse...

  11. The Faraday effect revisited: General theory

    DEFF Research Database (Denmark)

    Cornean, Horia Decebal; Nenciu, Gheorghe; Pedersen, Thomas Garm

    2006-01-01

    This paper is the first in a series revisiting the Faraday effect, or more generally, the theory of electronic quantum transport/optical response in bulk media in the presence of a constant magnetic field. The independent electron approximation is assumed. At zero temperature and zero frequency...

  12. Generalizations on the effectiveness of pharmaceutical promotional expenditures

    NARCIS (Netherlands)

    Kremer, S.T.M.; Bijmolt, T.H.A.; Leeflang, P.S.H.; Wieringa, J.E.

    2008-01-01

    We perform a meta-analysis to formulate generalizations on the effectiveness of pharmaceutical promotional instruments. A literature search on this topic yields 58 usable (published and unpublished) sources documenting 781 effects. We investigate different direct-to-physician (DTP) and

  13. Generalized uncertainty principles, effective Newton constant and regular black holes

    OpenAIRE

    Li, Xiang; Ling, Yi; Shen, You-Gen; Liu, Cheng-Zhou; He, Hong-Sheng; Xu, Lan-Fang

    2016-01-01

    In this paper, we explore the quantum spacetimes that are potentially connected with the generalized uncertainty principles. By analyzing the gravity-induced quantum interference pattern and the Gedanken for weighting photon, we find that the generalized uncertainty principles inspire the effective Newton constant as same as our previous proposal. A characteristic momentum associated with the tidal effect is suggested, which incorporates the quantum effect with the geometric nature of gravity...

  14. Effectiveness of empathy in general practice: a systematic review

    NARCIS (Netherlands)

    Derksen, F.; Bensing, J.; Lagro-Janssen, A.

    2013-01-01

    BACKGROUND: Empathy as a characteristic of patient-physician communication in both general practice and clinical care is considered to be the backbone of the patient-physician relationship. Although the value of empathy is seldom debated, its effectiveness is little discussed in general practice.

  15. Effectiveness of empathy in general practice: a systematic review.

    NARCIS (Netherlands)

    Derksen, F.; Bensing, J.; Lagro-Janssen, A.

    2013-01-01

    Background: Empathy as a characteristic of patient-physician communication in both general practice and clinical care is considered to be the backbone of the patient-physician relationship. Although the value of empathy is seldom debated, its effectiveness is little discussed in general practice.

  16. The Effects of General System Justification on Corruption Perception and Intent.

    Science.gov (United States)

    Tan, Xuyun; Liu, Li; Huang, Zhenwei; Zheng, Wenwen; Liang, Yuan

    2016-01-01

    Previous research stresses that system justifying belief can weaken corruption perception, by this possibly fostering unjust behaviors. However, general results of the effect of general system justification on corruption are ambiguous, indicating also a lessening impact. We conducted a line of studies trying to elucidate these circumstances by testing the effect of general system justification on corruption perception and intention. In addition, we explored institutional trust as a possible mediator in this process. For this purpose, we conducted three studies. The first two studies examined the association between general system justification and corruption. In Study 1, a correlational design was run using questionnaires to assess the relation between general system justification and corruption perception as well as corruption intention. In Study 2, an experimental design was conducted manipulating general system justification via exposure to high or low system threat condition, then measuring its effect on corruption perception and corrupt intention. In Study 3, two sub-studies using correlational and experimental designs were run to explore the mediating role of institutional trust, respectively. Results replicated former studies showing that general system justification is negatively associated with corruption perception. However, they also showed a negative correlation with corrupt intention. Furthermore, they showed that institutional trust mediated the relation between general system justification and corruption. We suggest to consider these findings to further elucidate the psychological basis underlying different effects of general system justification on human behaviors.

  17. The Effects of General System Justification on Corruption Perception and Intent

    Directory of Open Access Journals (Sweden)

    Xuyun Tan

    2016-07-01

    Full Text Available Previous research stresses that system justifying belief can weaken corruption perception, by this possibly fostering unjust behaviors. However, general results of the effect of general system justification on corruption are ambiguous, indicating also a lessening impact. We conducted a line of studies trying to elucidate these circumstances by testing the effect of general system justification on corruption perception and intention. In addition, we explored institutional trust as a possible mediator in this process. For this purpose we conducted three studies. The first two studies examined the association between general system justification and corruption. In Study 1, a correlational design was run using questionnaires to assess the relation between general system justification and corruption perception as well as corruption intention. In Study 2, an experimental design was conducted manipulating general system justification via exposure to high or low system threat condition, then measuring its effect on corruption perception and corrupt intention. In Study 3, two sub-studies using correlational and experimental designs were run to explore the mediating role of institutional trust, respectively. Results replicated former studies showing that general system justification is negatively associated with corruption perception. However, they also showed a negative correlation with corrupt intention. Furthermore, they showed that institutional trust mediated the relation between general system justification and corruption. We suggest to consider these findings to further elucidate the psychological basis underlying different effects of general system justification on human behaviors.

  18. Optical drift effects in general relativity

    Science.gov (United States)

    Korzyński, Mikołaj; Kopiński, Jarosław

    2018-03-01

    We consider the question of determining the optical drift effects in general relativity, i.e. the rate of change of the apparent position, redshift, Jacobi matrix, angular distance and luminosity distance of a distant object as registered by an observer in an arbitrary spacetime. We present a fully relativistic and covariant approach, in which the problem is reduced to a hierarchy of ODE's solved along the line of sight. The 4-velocities and 4-accelerations of the observer and the emitter and the geometry of the spacetime along the line of sight constitute the input data. We build on the standard relativistic geometric optics formalism and extend it to include the time derivatives of the observables. In the process we obtain two general, non-perturbative relations: the first one between the gravitational lensing, represented by the Jacobi matrix, and the apparent position drift, also called the cosmic parallax, and the second one between the apparent position drift and the redshift drift. The applications of the results include the theoretical study of the drift effects of cosmological origin (so-called real-time cosmology) in numerical or exact Universe models.

  19. Regular Gleason Measures and Generalized Effect Algebras

    Science.gov (United States)

    Dvurečenskij, Anatolij; Janda, Jiří

    2015-12-01

    We study measures, finitely additive measures, regular measures, and σ-additive measures that can attain even infinite values on the quantum logic of a Hilbert space. We show when particular classes of non-negative measures can be studied in the frame of generalized effect algebras.

  20. A general, multivariate definition of causal effects in epidemiology.

    Science.gov (United States)

    Flanders, W Dana; Klein, Mitchel

    2015-07-01

    Population causal effects are often defined as contrasts of average individual-level counterfactual outcomes, comparing different exposure levels. Common examples include causal risk difference and risk ratios. These and most other examples emphasize effects on disease onset, a reflection of the usual epidemiological interest in disease occurrence. Exposure effects on other health characteristics, such as prevalence or conditional risk of a particular disability, can be important as well, but contrasts involving these other measures may often be dismissed as non-causal. For example, an observed prevalence ratio might often viewed as an estimator of a causal incidence ratio and hence subject to bias. In this manuscript, we provide and evaluate a definition of causal effects that generalizes those previously available. A key part of the generalization is that contrasts used in the definition can involve multivariate, counterfactual outcomes, rather than only univariate outcomes. An important consequence of our generalization is that, using it, one can properly define causal effects based on a wide variety of additional measures. Examples include causal prevalence ratios and differences and causal conditional risk ratios and differences. We illustrate how these additional measures can be useful, natural, easily estimated, and of public health importance. Furthermore, we discuss conditions for valid estimation of each type of causal effect, and how improper interpretation or inferences for the wrong target population can be sources of bias.

  1. Radiogenic health effects: communicating risks to the general public

    International Nuclear Information System (INIS)

    Strzelczyk, Jadwiga

    1999-01-01

    Harmful effects of prolonged radiation exposures were recognized early on following the discovery of X-rays by W.C. Roentgen in 1895. The type and severity of radiogenic effects are functions of a number of factors, radiation quality and quantity, chemical toxicity, and radiosensitivity of irradiated tissues being the most significant ones. Currently, there are several human registries for radiogenic cancers. Atomic bomb and nuclear test survivors, and populations exposed to medical irradiation constitute the largest study cohorts. Two general types of radiogenic effects have emerged from these registries: prompt and delayed. While the effects of acute exposures are very well documented, investigations of the effects of low-level exposures require the use of mathematical models. Communicating the risks of lower-level chronic radiation exposures to the general public remains a challenging task. The most effective approaches include clear interpretation and placing radiation risks in perspective: risks versus benefits, and comparisons with risks carried by common activities in which we all engage. (author)

  2. The Faraday effect revisited General theory

    CERN Document Server

    Cornean, H D; Pedersen, T G

    2005-01-01

    This paper is the first in a series revisiting the Faraday effect, or more generally, the theory of electronic quantum transport/optical response in bulk media in the presence of a constant magnetic field. The independent electron approximation is assumed. For free electrons, the transverse conductivity can be explicitly computed and coincides with the classical result. In the general case, using magnetic perturbation theory, the conductivity tensor is expanded in powers of the strength of the magnetic field $B$. Then the linear term in $B$ of this expansion is written down in terms of the zero magnetic field Green function and the zero field current operator. In the periodic case, the linear term in $B$ of the conductivity tensor is expressed in terms of zero magnetic field Bloch functions and energies. No derivatives with respect to the quasimomentum appear and thereby all ambiguities are removed, in contrast to earlier work.

  3. Generalized effective mode volume for leaky optical cavities

    DEFF Research Database (Denmark)

    Kristensen, Philip Trøst; Van Vlack, C.; Hughes, S.

    2012-01-01

    We show explicitly how the commonly adopted prescription for calculating effective mode volumes is wrong and leads to uncontrolled errors. Instead, we introduce a generalized mode volume that can be easily evaluated based on the mode calculation methods typically applied in the literature, and wh......, and which allows one to compute the Purcell effect and other interesting optical phenomena in a rigorous and unambiguous way....

  4. Effects of music therapy under general anesthesia in patients ...

    African Journals Online (AJOL)

    Background: Music therapy, an innovative approach that has proven effectiveness in many medical conditions, seems beneficial also in managing surgical patients. The aim of this study is to evaluate its effects, under general anesthesia, on perioperative patient satisfaction, stress, pain, and awareness. Methods: This is a ...

  5. Generalized uncertainty principle as a consequence of the effective field theory

    Energy Technology Data Exchange (ETDEWEB)

    Faizal, Mir, E-mail: mirfaizalmir@gmail.com [Irving K. Barber School of Arts and Sciences, University of British Columbia – Okanagan, Kelowna, British Columbia V1V 1V7 (Canada); Department of Physics and Astronomy, University of Lethbridge, Lethbridge, Alberta T1K 3M4 (Canada); Ali, Ahmed Farag, E-mail: ahmed.ali@fsc.bu.edu.eg [Department of Physics, Faculty of Science, Benha University, Benha, 13518 (Egypt); Netherlands Institute for Advanced Study, Korte Spinhuissteeg 3, 1012 CG Amsterdam (Netherlands); Nassar, Ali, E-mail: anassar@zewailcity.edu.eg [Department of Physics, Zewail City of Science and Technology, 12588, Giza (Egypt)

    2017-02-10

    We will demonstrate that the generalized uncertainty principle exists because of the derivative expansion in the effective field theories. This is because in the framework of the effective field theories, the minimum measurable length scale has to be integrated away to obtain the low energy effective action. We will analyze the deformation of a massive free scalar field theory by the generalized uncertainty principle, and demonstrate that the minimum measurable length scale corresponds to a second more massive scale in the theory, which has been integrated away. We will also analyze CFT operators dual to this deformed scalar field theory, and observe that scaling of the new CFT operators indicates that they are dual to this more massive scale in the theory. We will use holographic renormalization to explicitly calculate the renormalized boundary action with counter terms for this scalar field theory deformed by generalized uncertainty principle, and show that the generalized uncertainty principle contributes to the matter conformal anomaly.

  6. Generalized uncertainty principle as a consequence of the effective field theory

    Directory of Open Access Journals (Sweden)

    Mir Faizal

    2017-02-01

    Full Text Available We will demonstrate that the generalized uncertainty principle exists because of the derivative expansion in the effective field theories. This is because in the framework of the effective field theories, the minimum measurable length scale has to be integrated away to obtain the low energy effective action. We will analyze the deformation of a massive free scalar field theory by the generalized uncertainty principle, and demonstrate that the minimum measurable length scale corresponds to a second more massive scale in the theory, which has been integrated away. We will also analyze CFT operators dual to this deformed scalar field theory, and observe that scaling of the new CFT operators indicates that they are dual to this more massive scale in the theory. We will use holographic renormalization to explicitly calculate the renormalized boundary action with counter terms for this scalar field theory deformed by generalized uncertainty principle, and show that the generalized uncertainty principle contributes to the matter conformal anomaly.

  7. The effectiveness of Cognitive Behavioral Therapy (CBT) with general exercises versus general exercises alone in the management of chronic low back pain.

    Science.gov (United States)

    Khan, Muhammad; Akhter, Saeed; Soomro, Rabail Rani; Ali, Syed Shahzad

    2014-07-01

    To evaluate the effectiveness of Cognitive Behavioural Therapy (CBT) along with General exercises and General exercises alone in chronic low back pain. Total 54 patients with chronic low back pain who fulfilled inclusion criteria were recruited from Physiotherapy, Department of Alain Poly Clinic Karachi and Institute of Physical Medicine & Rehabilitation Dow University of Health Sciences Karachi. Selected patients were equally divided and randomly assigned into two groups with simple randomisation method. The Cognitive Behavioural Therapy (CBT) and General exercises group received Operant model of CBT and General Exercises whereas General exercises group received General exercises only. Both groups received a home exercise program as well. Patients in both groups received 3 treatment sessions per week for 12 consecutive weeks. Clinical assessment was performed using Visual Analogue Scale (VAS) and Ronald Morris Disability Questionnaire at baseline and after 12 weeks. Both study groups showed statistically significant improvements in both outcomes measures p=0.000. However, mean improvements in post intervention VAS score and Ronald Morris score was better in CBT and exercises group as compared to General exercise group. In conclusion, both interventions are effective in treating chronic low back pain however; CBT & General exercises are clinically more effective than General exercises alone.

  8. Characteristics of effective clinical guidelines for general practice.

    NARCIS (Netherlands)

    Burgers, J.S.; Grol, R.P.T.M.; Zaat, J.O.M.; Spies, T.H.; Bij, A.K. van der; Mokkink, H.G.A.

    2003-01-01

    BACKGROUND: The use of clinical guidelines in general practice is often limited. Research on barriers to guideline adherence usually focuses on attitudinal factors. Factors linked to the guideline itself are much less studied. AIM: To identify characteristics of effective clinical guidelines for

  9. General relativistic galvano-gravitomagnetic effect in current carrying conductors

    International Nuclear Information System (INIS)

    Ahmedov, B.J.

    1998-11-01

    The analogy between general relativity and electromagnetism suggests that there is a galvano-gravitomagnetic effect, which is the gravitational analogue of the Hall effect. This new effect takes place when a current carrying conductor is placed in a gravitomagnetic field and the conduction electrons moving inside the conductor are deflected transversally with respect to the current flow. In connection with this galvano-gravitomagnetic effect, we explore the possibility of using current carrying conductors for detecting the gravitomagnetic field of the Earth. (author)

  10. More on PT-Symmetry in (Generalized Effect Algebras and Partial Groups

    Directory of Open Access Journals (Sweden)

    J. Paseka

    2011-01-01

    Full Text Available We continue in the direction of our paper on PT-Symmetry in (Generalized Effect Algebras and Partial Groups. Namely we extend our considerations to the setting of weakly ordered partial groups. In this setting, any operator weakly ordered partial group is a pasting of its partially ordered commutative subgroups of linear operators with a fixed dense domain over bounded operators. Moreover, applications of our approach for generalized effect algebras are mentioned.

  11. The effect of inclusion classrooms on the science achievement of general education students

    Science.gov (United States)

    Dodd, Matthew Robert

    General education and Special Education students from three high schools in Rutherford County were sampled to determine the effect on their academic achievement on the Tennessee Biology I Gateway Exam in Inclusion classrooms. Each student's predicted and actual Gateway Exam scores from the academic year 2006--2007 were used to determine the effect the student's classroom had on his academic achievement. Independent variables used in the study were gender, ethnicity, socioeconomic level, grade point average, type of classroom (general or Inclusion), and type student (General Education or Special Education). The statistical tests used in this study were a t-test and a Mann--Whitney U Test. From this study, the effect of the Inclusion classroom on general education students was not significant statistically. Although the Inclusion classroom allows the special education student to succeed in the classroom, the effect on general education students is negligible. This study also provided statistical data that the Inclusion classroom did not improve the special education students' academic performances on the Gateway Exam. Students in a general education classroom with a GPA above 3.000 and those from a household without a low socioeconomic status performed at a statistically different level in this study.

  12. Different goods, different effects: Exploring the effects of generalized social trust in large-N collective action

    DEFF Research Database (Denmark)

    Sønderskov, Kim Mannemar

    2009-01-01

    Does generalized social trust help solve large-N collective action problems? This paper argues so, offering a novel explanation for the relationship: People tend to cooperate if they expect others to be cooperating, which implies that people holding generalized social trust more readily cooperate...... in large-N dilemmas because they expect that most people will cooperate. The paper tests the explanation in a rigorous design. The analyses show a positive, robust effect of generalized social trust on public good provision, but no effect is found in a joint product situation. This supports the hypothesis......, indicating that trust specifically enhances cooperation in collective action dilemmas....

  13. Effects of music therapy under general anesthesia in patients ...

    African Journals Online (AJOL)

    2016-12-13

    Dec 13, 2016 ... The aim of this study is to evaluate its effects, under general anesthesia, on perioperative patient satisfaction, ..... Morphine consumption was lower in the ... psychological consequences such as post-traumatic stress disorder ...

  14. A General Model for Testing Mediation and Moderation Effects

    Science.gov (United States)

    MacKinnon, David P.

    2010-01-01

    This paper describes methods for testing mediation and moderation effects in a dataset, both together and separately. Investigations of this kind are especially valuable in prevention research to obtain information on the process by which a program achieves its effects and whether the program is effective for subgroups of individuals. A general model that simultaneously estimates mediation and moderation effects is presented, and the utility of combining the effects into a single model is described. Possible effects of interest in the model are explained, as are statistical methods to assess these effects. The methods are further illustrated in a hypothetical prevention program example. PMID:19003535

  15. Generalized Born Models of Macromolecular Solvation Effects

    Science.gov (United States)

    Bashford, Donald; Case, David A.

    2000-10-01

    It would often be useful in computer simulations to use a simple description of solvation effects, instead of explicitly representing the individual solvent molecules. Continuum dielectric models often work well in describing the thermodynamic aspects of aqueous solvation, and approximations to such models that avoid the need to solve the Poisson equation are attractive because of their computational efficiency. Here we give an overview of one such approximation, the generalized Born model, which is simple and fast enough to be used for molecular dynamics simulations of proteins and nucleic acids. We discuss its strengths and weaknesses, both for its fidelity to the underlying continuum model and for its ability to replace explicit consideration of solvent molecules in macromolecular simulations. We focus particularly on versions of the generalized Born model that have a pair-wise analytical form, and therefore fit most naturally into conventional molecular mechanics calculations.

  16. Vibrational mechanics nonlinear dynamic effects, general approach, applications

    CERN Document Server

    Blekhman, Iliya I

    2000-01-01

    This important book deals with vibrational mechanics - the new, intensively developing section of nonlinear dynamics and the theory of nonlinear oscillations. It offers a general approach to the study of the effect of vibration on nonlinear mechanical systems.The book presents the mathematical apparatus of vibrational mechanics which is used to describe such nonlinear effects as the disappearance and appearance under vibration of stable positions of equilibrium and motions (i.e. attractors), the change of the rheological properties of the media, self-synchronization, self-balancing, the vibrat

  17. Distinguishing f(R) theories from general relativity by gravitational lensing effect

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hongguang [Beijing Normal University, Department of Physics, Beijing (China); Aix Marseille Universite et Universite de Toulon, Centre de Physique Theorique (UMR 7332), Marseille (France); Wang, Xin; Li, Haida; Ma, Yongge [Beijing Normal University, Department of Physics, Beijing (China)

    2017-11-15

    The post-Newtonian formulation of a general class of f(R) theories is set up in a third-order approximation. It turns out that the information of a specific form of f(R) gravity is encoded in the Yukawa potential, which is contained in the perturbative expansion of the metric components. Although the Yukawa potential is canceled in the second-order expression of the effective refraction index of light, detailed analysis shows that the difference of the lensing effect between the f(R) gravity and general relativity does appear at the third order when √(f''(0)/f{sup '}(0)) is larger than the distance d{sub 0} to the gravitational source. However, the difference between these two kinds of theories will disappear in the axially symmetric spacetime region. Therefore only in very rare case the f(R) theories are distinguishable from general relativity by gravitational lensing effect in a third-order post-Newtonian approximation. (orig.)

  18. Generalized model of the microwave auditory effect

    International Nuclear Information System (INIS)

    Yitzhak, N M; Ruppin, R; Hareuveny, R

    2009-01-01

    A generalized theoretical model for evaluating the amplitudes of the sound waves generated in a spherical head model, which is irradiated by microwave pulses, is developed. The thermoelastic equation of motion is solved for a spherically symmetric heating pattern of arbitrary form. For previously treated heating patterns that are peaked at the sphere centre, the results reduce to those presented before. The generalized model is applied to the case in which the microwave absorption is concentrated near the sphere surface. It is found that, for equal average specific absorption rates, the sound intensity generated by a surface localized heating pattern is comparable to that generated by a heating pattern that is peaked at the centre. The dependence of the induced sound pressure on the shape of the microwave pulse is explored. Another theoretical extension, to the case of repeated pulses, is developed and applied to the interpretation of existing experimental data on the dependence of the human hearing effect threshold on the pulse repetition frequency.

  19. Generalized Effective Medium Theory for Particulate Nanocomposite Materials

    Directory of Open Access Journals (Sweden)

    Muhammad Usama Siddiqui

    2016-08-01

    Full Text Available The thermal conductivity of particulate nanocomposites is strongly dependent on the size, shape, orientation and dispersion uniformity of the inclusions. To correctly estimate the effective thermal conductivity of the nanocomposite, all these factors should be included in the prediction model. In this paper, the formulation of a generalized effective medium theory for the determination of the effective thermal conductivity of particulate nanocomposites with multiple inclusions is presented. The formulated methodology takes into account all the factors mentioned above and can be used to model nanocomposites with multiple inclusions that are randomly oriented or aligned in a particular direction. The effect of inclusion dispersion non-uniformity is modeled using a two-scale approach. The applications of the formulated effective medium theory are demonstrated using previously published experimental and numerical results for several particulate nanocomposites.

  20. General aspects of nuclear power, radiation and environmental effects. Chapter 3

    International Nuclear Information System (INIS)

    1978-01-01

    A general introduction to the principles of the functioning of a nuclear reactor and of power plants based on the reactor types at present in use, and likely to be used in the near future (PWR,BWR,FBR,HTGR and CANDU) is given. The general principles of a thermonuclear power plant are also briefly presented, and general safety aspects discussed. The physics of ionising radiations is briefly presented and natural and artificial sources of radiation are discussed. The fuel cycle, from mining to reprocessing and waste disposal and transport, is presented. The behaviour and effects of radioactive substances in the biosphere, radiation doses, and biological effects of ionising radiation are discussed. In conclusion there is an appendix in which the main characteristics of a number of elements which have important radioactive isotopes are presented. (JIW)

  1. The effect of Malaysia general election on stock market returns.

    Science.gov (United States)

    Liew, Venus Khim-Sen; Rowland, Racquel

    2016-01-01

    During the latest episode of general election held in Malaysia, it is observed that the FBMKLCI index was lifted 62.52 points in a day soon after the announcement of election outcome. Moreover, the index registered a highest gain of 96.29 points in the middle of the intra-day trade. This suggests that investors who had got the right direction could make profitable intra-day trading the next trading day of the general election date. Results from statistical analysis uncover significant before-election-effect and after-election-effect from the most recent general elections held in Malaysia. Different subsets of macroeconomic variables are found to have significant role on stock market return depending on the market situation. Remarkably, when there was close fight between the two major political parties during the 2008 and 2013 election years, political uncertainty showed up its negative and significant role in influencing the stock market return. The major implication of these findings is that while investors may seek abnormal returns before and after the next general election, which is around the corner, they will have to pay attention on the influence of macroeconomic variables and political uncertainty on stock market return during the election year.

  2. Machian effects in general relativity

    International Nuclear Information System (INIS)

    Embacher, F.

    1988-01-01

    As a consequence of Mach's principle, rotating matter should cause local inertial frames or gyroscopes in its vicinity to undergo a small rotation which is not present in the Newtonian picture. H. Thirring and J. Lense were the first to derive similar predictions from the field equations of general relativity. Since these early days of relativity, a lot of exact and approximate solutions to Einstein's equations have been examined under this point of view. The qualitative features of Machian effects are most easily demonstrated in the cylinder symmetric case, where some exact results are available. For example, space-time is flat inside a uniformly rotating matter shell, and the rotation of this interior with respect to 'infinity' (the distant stars) has a clear meaning. In the more realistic case of what happens near a massive rotating star, one is forced to perform certain approximations. In modern language, Machian effects are described in terms of the twist of timelike killing vector fields. In the linearized theory, the equations that determine the Machian structure generated by a given matter distribution, resemble to some extent those of classical electrodynamics. This correspondence provides a pedagogical approach how to compute the quantitative extent of inertial frame 'dragging'. 6 refs., 5 figs. (Author)

  3. Understanding the "Weekend Effect" for Emergency General Surgery.

    Science.gov (United States)

    Hoehn, Richard S; Go, Derek E; Dhar, Vikrom K; Kim, Young; Hanseman, Dennis J; Wima, Koffi; Shah, Shimul A

    2018-02-01

    Several studies have identified a "weekend effect" for surgical outcomes, but definitions vary and the cause is unclear. Our aim was to better characterize the weekend effect for emergency general surgery using mortality as a primary endpoint. Using data from the University HealthSystem Consortium from 2009 to 2013, we identified urgent/emergent hospital admissions for seven procedures representing 80% of the national burden of emergency general surgery. Patient characteristics and surgical outcomes were compared between cases that were performed on weekdays vs weekends. Hospitals varied widely in the proportion of procedures performed on the weekend. Of the procedures examined, four had higher mortality for weekend cases (laparotomy, lysis of adhesions, partial colectomy, and small bowel resection; p < 0.01), while three did not (appendectomy, cholecystectomy, and peptic ulcer disease repair). Among the four procedures with increased weekend mortality, patients undergoing weekend procedures also had increased severity of illness and shorter time from admission to surgery (p < 0.01). Multivariate analysis adjusting for patient characteristics demonstrated independently higher mortality on weekends for these same four procedures (p < 0.01). For the first time, we have identified specific emergency general surgery procedures that incur higher mortality when performed on weekends. This may be due to acute changes in patient status that require weekend surgery or indications for urgent procedures (ischemia, obstruction) compared to those without a weekend mortality difference (infection). Hospitals that perform weekend surgery must acknowledge and identify ways to manage this increased risk.

  4. Different goods, different effects: Exploring the roles of generalized trust in public goods provision

    DEFF Research Database (Denmark)

    Sønderskov, Kim

    -product situation (whether to buy organic food or not). This design provides a possibility to detect whether any effect of generalized trust is due to strategic behavior or due to altruistic motives among trusters. The results show that generalized trust enhances recycling significantly whereas it only has a very......This paper tests the hypothesis that generalized trust helps solve large-n collective action problems in a rationalistic framework. A rigors test is employed in that the hypothesis is tested in two different choice situations; a pure public good situation (whether to recycle or not) and a joint...... week positive effect on organic food consumption. Hence, generalized trust only affects public good provision when a collective action problem is present. The analyses thus sustain the hypothesis. It is furthermore concluded that the effect of generalized trust is due to strategic behavior...

  5. Does the dilution effect generally occur in animal diseases?

    NARCIS (Netherlands)

    Huang, Zheng Y.X.; Yu, Yang; Langevelde, Van Frank; Boer, De Willem F.

    2017-01-01

    The dilution effect (DE) has been reported in many diseases, but its generality is still highly disputed. Most current criticisms of DE are related to animal diseases. Particularly, some critical studies argued that DE is less likely to occur in complex environments. Here our meta-analyses

  6. Generalized Superconductivity. Generalized Levitation

    International Nuclear Information System (INIS)

    Ciobanu, B.; Agop, M.

    2004-01-01

    In the recent papers, the gravitational superconductivity is described. We introduce the concept of generalized superconductivity observing that any nongeodesic motion and, in particular, the motion in an electromagnetic field, can be transformed in a geodesic motion by a suitable choice of the connection. In the present paper, the gravitoelectromagnetic London equations have been obtained from the generalized Helmholtz vortex theorem using the generalized local equivalence principle. In this context, the gravitoelectromagnetic Meissner effect and, implicitly, the gravitoelectromagnetic levitation are given. (authors)

  7. Generalized linear models with random effects unified analysis via H-likelihood

    CERN Document Server

    Lee, Youngjo; Pawitan, Yudi

    2006-01-01

    Since their introduction in 1972, generalized linear models (GLMs) have proven useful in the generalization of classical normal models. Presenting methods for fitting GLMs with random effects to data, Generalized Linear Models with Random Effects: Unified Analysis via H-likelihood explores a wide range of applications, including combining information over trials (meta-analysis), analysis of frailty models for survival data, genetic epidemiology, and analysis of spatial and temporal models with correlated errors.Written by pioneering authorities in the field, this reference provides an introduction to various theories and examines likelihood inference and GLMs. The authors show how to extend the class of GLMs while retaining as much simplicity as possible. By maximizing and deriving other quantities from h-likelihood, they also demonstrate how to use a single algorithm for all members of the class, resulting in a faster algorithm as compared to existing alternatives. Complementing theory with examples, many of...

  8. Problem solving therapy - use and effectiveness in general practice.

    Science.gov (United States)

    Pierce, David

    2012-09-01

    Problem solving therapy (PST) is one of the focused psychological strategies supported by Medicare for use by appropriately trained general practitioners. This article reviews the evidence base for PST and its use in the general practice setting. Problem solving therapy involves patients learning or reactivating problem solving skills. These skills can then be applied to specific life problems associated with psychological and somatic symptoms. Problem solving therapy is suitable for use in general practice for patients experiencing common mental health conditions and has been shown to be as effective in the treatment of depression as antidepressants. Problem solving therapy involves a series of sequential stages. The clinician assists the patient to develop new empowering skills, and then supports them to work through the stages of therapy to determine and implement the solution selected by the patient. Many experienced GPs will identify their own existing problem solving skills. Learning about PST may involve refining and focusing these skills.

  9. Effects of Aging on General and Specific Memory for Impressions

    Directory of Open Access Journals (Sweden)

    Megan J. Limbert

    2018-05-01

    Full Text Available Despite the number of documented declines in memory with age, memory for socioemotional information can be preserved into older adulthood. These studies assessed whether memory for character information could be preserved with age, and how the general versus specific nature of the information tested affected outcomes. We hypothesized that memory for general impressions would be preserved with age, but that memory for specific details would be impaired. In two experiments, younger and older adults learned character information about individuals characterized as positive, neutral, or negative. Participants then retrieved general impressions and specific information for each individual. The testing conditions in Experiment 2 discouraged deliberate recall. In Experiment 1, we found that younger performed better than older adults on both general and specific memory measures. Although age differences in memory for specific information persisted in Experiment 2, we found that younger and older adults remembered general impressions to a similar extent when testing conditions encouraged the use of “gut impressions” rather than deliberate retrieval from memory. We conclude that aging affects memory for specific character information, but memory for general impressions can be age-equivalent. Furthermore, there is no evidence for a positivity bias or differences in the effects of valence on memory across the age groups.

  10. Effective action for scalar fields and generalized zeta-function regularization

    International Nuclear Information System (INIS)

    Cognola, Guido; Zerbini, Sergio

    2004-01-01

    Motivated by the study of quantum fields in a Friedmann-Robertson-Walker space-time, the one-loop effective action for a scalar field defined in the ultrastatic manifold RxH 3 /Γ, H 3 /Γ being the finite volume, noncompact, hyperbolic spatial section, is investigated by a generalization of zeta-function regularization. It is shown that additional divergences may appear at the one-loop level. The one-loop renormalizability of the model is discussed and, making use of a generalization of zeta-function regularization, the one-loop renormalization group equations are derived

  11. Proposed new test of spin effects in general relativity.

    Science.gov (United States)

    O'Connell, R F

    2004-08-20

    The recent discovery of a double-pulsar PSR J0737-3039A/B provides an opportunity of unequivocally observing, for the first time, spin effects in general relativity. Existing efforts involve detection of the precession of the spinning body itself. However, for a close binary system, spin effects on the orbit may also be discernible. Not only do they add to the advance of the periastron (by an amount which is small compared to the conventional contribution) but they also give rise to a precession of the orbit about the spin direction. The measurement of such an effect would also give information on the moment of inertia of pulsars.

  12. Testing for constant nonparametric effects in general semiparametric regression models with interactions

    KAUST Repository

    Wei, Jiawei

    2011-07-01

    We consider the problem of testing for a constant nonparametric effect in a general semi-parametric regression model when there is the potential for interaction between the parametrically and nonparametrically modeled variables. The work was originally motivated by a unique testing problem in genetic epidemiology (Chatterjee, et al., 2006) that involved a typical generalized linear model but with an additional term reminiscent of the Tukey one-degree-of-freedom formulation, and their interest was in testing for main effects of the genetic variables, while gaining statistical power by allowing for a possible interaction between genes and the environment. Later work (Maity, et al., 2009) involved the possibility of modeling the environmental variable nonparametrically, but they focused on whether there was a parametric main effect for the genetic variables. In this paper, we consider the complementary problem, where the interest is in testing for the main effect of the nonparametrically modeled environmental variable. We derive a generalized likelihood ratio test for this hypothesis, show how to implement it, and provide evidence that our method can improve statistical power when compared to standard partially linear models with main effects only. We use the method for the primary purpose of analyzing data from a case-control study of colorectal adenoma.

  13. Substitution effects in a generalized token economy with pigeons.

    Science.gov (United States)

    Andrade, Leonardo F; Hackenberg, Timothy D

    2017-01-01

    Pigeons made repeated choices between earning and exchanging reinforcer-specific tokens (green tokens exchangeable for food, red tokens exchangeable for water) and reinforcer-general tokens (white tokens exchangeable for food or water) in a closed token economy. Food and green food tokens could be earned on one panel; water and red water tokens could be earned on a second panel; white generalized tokens could be earned on either panel. Responses on one key produced tokens according to a fixed-ratio schedule, whereas responses on a second key produced exchange periods, during which all previously earned tokens could be exchanged for the appropriate commodity. Most conditions were conducted in a closed economy, and pigeons distributed their token allocation in ways that permitted food and water consumption. When the price of all tokens was equal and low, most pigeons preferred the generalized tokens. When token-production prices were manipulated, pigeons reduced production of the tokens that increased in price while increasing production of the generalized tokens that remained at a fixed price. The latter is consistent with a substitution effect: Generalized tokens increased and were exchanged for the more expensive reinforcer. When food and water were made freely available outside the session, token production and exchange was sharply reduced but was not eliminated, even in conditions when it no longer produced tokens. The results join with other recent data in showing sustained generalized functions of token reinforcers, and demonstrate the utility of token-economic methods for assessing demand for and substitution among multiple commodities in a laboratory context. © 2016 Society for the Experimental Analysis of Behavior.

  14. A general multiscale framework for the emergent effective elastodynamics of metamaterials

    Science.gov (United States)

    Sridhar, A.; Kouznetsova, V. G.; Geers, M. G. D.

    2018-02-01

    This paper presents a general multiscale framework towards the computation of the emergent effective elastodynamics of heterogeneous materials, to be applied for the analysis of acoustic metamaterials and phononic crystals. The generality of the framework is exemplified by two key characteristics. First, the underlying formalism relies on the Floquet-Bloch theorem to derive a robust definition of scales and scale separation. Second, unlike most homogenization approaches that rely on a classical volume average, a generalized homogenization operator is defined with respect to a family of particular projection functions. This yields a generalized macro-scale continuum, instead of the classical Cauchy continuum. This enables (in a micromorphic sense) to homogenize the rich dispersive behavior resulting from both Bragg scattering and local resonance. For an arbitrary unit cell, the homogenization projection functions are constructed using the Floquet-Bloch eigenvectors obtained in the desired frequency regime at select high symmetry points, which effectively resolves the emergent phenomena dominating that regime. Furthermore, a generalized Hill-Mandel condition is proposed that ensures power consistency between the homogenized and full-scale model. A high-order spatio-temporal gradient expansion is used to localize the multiscale problem leading to a series of recursive unit cell problems giving the appropriate micro-mechanical corrections. The developed multiscale method is validated against standard numerical Bloch analysis of the dispersion spectra of example unit cells encompassing multiple high-order branches generated by local resonance and/or Bragg scattering.

  15. Cost-effectiveness analysis of HPV vaccination: comparing the general population with socially vulnerable individuals.

    Science.gov (United States)

    Han, Kyu-Tae; Kim, Sun Jung; Lee, Seo Yoon; Park, Eun-Cheol

    2014-01-01

    After the WHO recommended HPV vaccination of the general population in 2009, government support of HPV vaccination programs was increased in many countries. However, this policy was not implemented in Korea due to perceived low cost-effectiveness. Thus, the aim of this study was to analyze the cost-utility of HPV vaccination programs targeted to high risk populations as compared to vaccination programs for the general population. Each study population was set to 100,000 people in a simulation study to determine the incremental cost-utility ratio (ICUR), then standard prevalence rates, cost, vaccination rates, vaccine efficacy, and the Quality-Adjusted Life-Years (QALYs) were applied to the analysis. In addition, sensitivity analysis was performed by assuming discounted vaccination cost. In the socially vulnerable population, QALYs gained through HPV vaccination were higher than that of the general population (General population: 1,019, Socially vulnerable population: 5,582). The results of ICUR showed that the cost of HPV vaccination was higher for the general population than the socially vulnerable population. (General population: 52,279,255 KRW, Socially vulnerable population: 9,547,347 KRW). Compared with 24 million KRW/QALYs as the social threshold, vaccination of the general population was not cost-effective. In contrast, vaccination of the socially vulnerable population was strongly cost-effective. The results suggest the importance and necessity of government support of HPV vaccination programs targeted to socially vulnerable populations because a targeted approach is much more cost-effective. The implementation of government support for such vaccination programs is a critical strategy for decreasing the burden of HPV infection in Korea.

  16. General Friction Model Extended by the Effect of Strain Hardening

    DEFF Research Database (Denmark)

    Nielsen, Chris V.; Martins, Paulo A.F.; Bay, Niels

    2016-01-01

    An extension to the general friction model proposed by Wanheim and Bay [1] to include the effect of strain hardening is proposed. The friction model relates the friction stress to the fraction of real contact area by a friction factor under steady state sliding. The original model for the real...... contact area as function of the normalized contact pressure is based on slip-line analysis and hence on the assumption of rigid-ideally plastic material behavior. In the present work, a general finite element model is established to, firstly, reproduce the original model under the assumption of rigid...

  17. Generalized polymer effective charge measurement by capillary isotachophoresis.

    Science.gov (United States)

    Chamieh, Joseph; Koval, Dušan; Besson, Adeline; Kašička, Václav; Cottet, Hervé

    2014-11-28

    In this work, we have generalized the use of capillary isotachophoresis as a universal method for determination of effective charge of anionic and cationic (co)polymers on ordinary capillary electrophoresis instruments. This method is applicable to a broad range of strong or weak polyelectrolytes with good repeatability. Experimental parameters (components and concentrations of leading and terminating electrolytes, capillary diameters, constant electric current intensity) were optimized for implementation in 100 μm i.d. capillaries for both polyanions and polycations. Determined values of polymer effective charge were in a very good agreement with those obtained by capillary electrophoresis with indirect UV detection. Uncertainty of the effective charge measurement using isotachophoresis was addressed and estimated to be ∼5-10% for solutes with mobilities in the 20-50 × 10(-9)m(2)V(-1)s(-1) range. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. Effectiveness of oncogenetics training on general practitioners' consultation skills: a randomized controlled trial

    NARCIS (Netherlands)

    Houwink, E.J.; Muijtjens, A.M.M.; Teeffelen, S.R. van; Henneman, L.; Rethans, J.J.; Jagt, L.E. van der; Luijk, S.J. van; Dinant, G.J.; Vleuten, C.P.M. van der; Cornel, M.C.

    2014-01-01

    PURPOSE: General practitioners are increasingly called upon to deliver genetic services and could play a key role in translating potentially life-saving advancements in oncogenetic technologies to patient care. If general practitioners are to make an effective contribution in this area, their

  19. Effectiveness of oncogenetics training on general practitioners' consultation skills: a randomized controlled trial

    NARCIS (Netherlands)

    Houwink, E.J.F.; Muijtjens, A.M.M.; van Teeffelen, S.R.; Henneman, L.; Rethans, J.J.; van der Jagt, L.E.J.; van Luijk, S.J.; Dinant, G.J.; van der Vleuten, C.; Cornel, M.C.

    2014-01-01

    Purpose:General practitioners are increasingly called upon to deliver genetic services and could play a key role in translating potentially life-saving advancements in oncogenetic technologies to patient care. If general practitioners are to make an effective contribution in this area, their

  20. General survey of non-neoplastic radiation effects

    International Nuclear Information System (INIS)

    Silini, G.

    1983-01-01

    The 1982 report of UNSCEAR analysed a large body of information on the non-tumourous consequences of irradiation after partial- and whole-body exposure. Based on that analysis this review discusses, for partial-body exposure, the major points relating to morphological and functional non-stochastic early effects such as induction mechanisms, relationships with dose, time and radiation quality, and specific nature of the effects in various tissues. The review specifically considers doses and effects that are likely to be critical under conditions of highly fractionated and long-term exposure. It shows that for organ irradiation the presence of a dose threshold is the most important characteristic of non-stochastic effects. The significance of the threshold in relation to mechanisms, its dependence on physical or biological variables and its practical significance are particularly commented upon. The review considers the distinctive features of early effects of whole-body irradiation and late effects of partial-body exposure and underlines their main interest under accident conditions and for medical treatment, respectively. As to late consequences of whole-body irradiation, lifespan shortening is the effect specifically considered. The review discusses the basic aspects of the life shortening action, such as general definitions, relationships to physiological ageing, technical and methodological assessment and relationships to other specific or non-specific effects of radiation. Data on life shortening in various animal species are briefly reviewed under the form of dose relationships for short-term and lifelong exposures with some discussion of human data. The conclusion is drawn that, in the light of present evidence, at the low doses and dose rates which are most important in practice, life shortening appears to be due essentially to the induction of tumours. (author)

  1. 77 FR 37283 - General Provisions; Operating and Strategic Business Planning; Effective Date

    Science.gov (United States)

    2012-06-21

    ... directors of each Farm Credit System institution to adopt an operational and strategic business plan to... FARM CREDIT ADMINISTRATION 12 CFR Part 618 RIN 3052-AC66 General Provisions; Operating and Strategic Business Planning; Effective Date AGENCY: Farm Credit Administration. ACTION: Notice of effective...

  2. Treatment of cloud radiative effects in general circulation models

    Energy Technology Data Exchange (ETDEWEB)

    Wang, W.C.; Dudek, M.P.; Liang, X.Z.; Ding, M. [State Univ. of New York, Albany, NY (United States)] [and others

    1996-04-01

    We participate in the Atmospheric Radiation Measurement (ARM) program with two objectives: (1) to improve the general circulation model (GCM) cloud/radiation treatment with a focus on cloud verticle overlapping and layer cloud optical properties, and (2) to study the effects of cloud/radiation-climate interaction on GCM climate simulations. This report summarizes the project progress since the Fourth ARM Science Team meeting February 28-March 4, 1994, in Charleston, South Carolina.

  3. General extrapolation model for an important chemical dose-rate effect

    International Nuclear Information System (INIS)

    Gillen, K.T.; Clough, R.L.

    1984-12-01

    In order to extrapolate material accelerated aging data, methodologies must be developed based on sufficient understanding of the processes leading to material degradation. One of the most important mechanisms leading to chemical dose-rate effects in polymers involves the breakdown of intermediate hydroperoxide species. A general model for this mechanism is derived based on the underlying chemical steps. The results lead to a general formalism for understanding dose rate and sequential aging effects when hydroperoxide breakdown is important. We apply the model to combined radiation/temperature aging data for a PVC material and show that this data is consistent with the model and that model extrapolations are in excellent agreement with 12-year real-time aging results from an actual nuclear plant. This model and other techniques discussed in this report can aid in the selection of appropriate accelerated aging methods and can also be used to compare and select materials for use in safety-related components. This will result in increased assurance that equipment qualification procedures are adequate

  4. Methotrexate: an effective monotherapy for refractory generalized morphea

    Directory of Open Access Journals (Sweden)

    Platsidaki E

    2017-05-01

    Full Text Available Eftychia Platsidaki, Vassiliki Tzanetakou, Anargyros Kouris, Panagiotis G Stavropoulos Department of Dermatology and Venereology, Andreas Syggros Hospital, University of Athens, Athens, Greece Introduction: Morphea is an inflammatory skin disorder characterized by excessive collagen deposition. Although treatment algorithms for morphea subtypes have been suggested, no consistent recommendations are available. This study attempts to evaluate the clinical efficacy of methotrexate (MTX as monotherapy in refractory generalized morphea. Methods: It is a retrospective study, including 20 patients who had already been treated with various topical and systemic therapies with minimal clinical improvement. Patients received orally MTX at a of dosage 15 mg once weekly. Duration of the use, dosage of MTX, and adverse events were recorded. Clinical assessment of skin lesions was performed and documented. Results: The mean disease duration was 27 months before the initiation of MTX treatment. After 12 months of therapy, very good response was achieved in 6 patients (30%, good response in 10 patients (50%, and fair response in 2 patients (10%, while 2 patients (10% had failed treatment. Patients were followed up for a mean time interval of 21 months. No serious adverse event was recorded. Conclusion: MTX has been already proved to be an effective and well-tolerated treatment in pediatric patients with morphea. The majority of the group of adult patients showed very good and good improvement when treated with MTX. Although this is an uncontrolled study, MTX monotherapy was considered a safe and effective treatment for the management of this specific clinical subset of morphea in adults. Keywords: methotrexate, adults, generalized morphea

  5. A confirmation of the general relativistic prediction of the Lense-Thirring effect.

    Science.gov (United States)

    Ciufolini, I; Pavlis, E C

    2004-10-21

    An important early prediction of Einstein's general relativity was the advance of the perihelion of Mercury's orbit, whose measurement provided one of the classical tests of Einstein's theory. The advance of the orbital point-of-closest-approach also applies to a binary pulsar system and to an Earth-orbiting satellite. General relativity also predicts that the rotation of a body like Earth will drag the local inertial frames of reference around it, which will affect the orbit of a satellite. This Lense-Thirring effect has hitherto not been detected with high accuracy, but its detection with an error of about 1 per cent is the main goal of Gravity Probe B--an ongoing space mission using orbiting gyroscopes. Here we report a measurement of the Lense-Thirring effect on two Earth satellites: it is 99 +/- 5 per cent of the value predicted by general relativity; the uncertainty of this measurement includes all known random and systematic errors, but we allow for a total +/- 10 per cent uncertainty to include underestimated and unknown sources of error.

  6. Ionic Size Effects: Generalized Boltzmann Distributions, Counterion Stratification, and Modified Debye Length.

    Science.gov (United States)

    Liu, Bo; Liu, Pei; Xu, Zhenli; Zhou, Shenggao

    2013-10-01

    Near a charged surface, counterions of different valences and sizes cluster; and their concentration profiles stratify. At a distance from such a surface larger than the Debye length, the electric field is screened by counterions. Recent studies by a variational mean-field approach that includes ionic size effects and by Monte Carlo simulations both suggest that the counterion stratification is determined by the ionic valence-to-volume ratios. Central in the mean-field approach is a free-energy functional of ionic concentrations in which the ionic size effects are included through the entropic effect of solvent molecules. The corresponding equilibrium conditions define the generalized Boltzmann distributions relating the ionic concentrations to the electrostatic potential. This paper presents a detailed analysis and numerical calculations of such a free-energy functional to understand the dependence of the ionic charge density on the electrostatic potential through the generalized Boltzmann distributions, the role of ionic valence-to-volume ratios in the counterion stratification, and the modification of Debye length due to the effect of ionic sizes.

  7. Study on the nonlocality effects for generalized optical potentials

    International Nuclear Information System (INIS)

    Gurbanovich, I.S.; Zelenskaya, N.S.

    1981-01-01

    In previous studies the authors have ihown that the generalized optic potential (GOP) of particles interaction is a superposition of local and non local potentials (LP, NLP). On the example of α- particles scattering on the 8 Be nucleus at about 10-15 MeV the GOP nonlocal part is considered. For obtaining NLP the spectral decomposition of the Green function taking into account only contribution of relative motion of two α-particles in S-state is used. The locally-equivalent addition to central potential of α-particles scattering at 8 Be previously calculated is obtained. In a graphical form a total locally-equivalent potential and local GOP part are presented. It is shown that taking into account the nonlocallity effect in a locally energy approximation for precise wave function in S-state widen a potential hole without changing its depth. Such widening corresponds to the general character of behaviour of non local potentials calculated in the microscopic approach [ru

  8. The Effects of Echolalia on Acquisition and Generalization of Receptive Labeling in Autistic Children.

    Science.gov (United States)

    Charlop, Marjorie H.

    1983-01-01

    Two experiments, with about five autistic children (two to 14 years old) in each experiment, assessed the effects of autistic immediate echolalia on acquisition and generalization of receptive labeling tasks. These results indicated that echolalia faciliated generalization for echolalic autistic children but not for functionally mute autistic…

  9. Effectiveness of oncogenetics training on general practitioners' consultation skills: a randomized controlled trial.

    Science.gov (United States)

    Houwink, Elisa J F; Muijtjens, Arno M M; van Teeffelen, Sarah R; Henneman, Lidewij; Rethans, Jan Joost; van der Jagt, Liesbeth E J; van Luijk, Scheltus J; Dinant, Geert Jan; van der Vleuten, Cees; Cornel, Martina C

    2014-01-01

    General practitioners are increasingly called upon to deliver genetic services and could play a key role in translating potentially life-saving advancements in oncogenetic technologies to patient care. If general practitioners are to make an effective contribution in this area, their genetics competencies need to be upgraded. The aim of this study was to investigate whether oncogenetics training for general practitioners improves their genetic consultation skills. In this pragmatic, blinded, randomized controlled trial, the intervention consisted of a 4-h training (December 2011 and April 2012), covering oncogenetic consultation skills (family history, familial risk assessment, and efficient referral), attitude (medical ethical issues), and clinical knowledge required in primary-care consultations. Outcomes were measured using observation checklists by unannounced standardized patients and self-reported questionnaires. Of 88 randomized general practitioners who initially agreed to participate, 56 completed all measurements. Key consultation skills significantly and substantially improved; regression coefficients after intervention were equivalent to 0.34 and 0.28 at 3-month follow-up, indicating a moderate effect size. Satisfaction and perceived applicability of newly learned skills were highly scored. The general practitioner-specific training proved to be a feasible, satisfactory, and clinically applicable method to improve oncogenetics consultation skills and could be used as an educational framework to inform future training activities with the ultimate aim of improving medical care.

  10. Testing for constant nonparametric effects in general semiparametric regression models with interactions

    KAUST Repository

    Wei, Jiawei; Carroll, Raymond J.; Maity, Arnab

    2011-01-01

    We consider the problem of testing for a constant nonparametric effect in a general semi-parametric regression model when there is the potential for interaction between the parametrically and nonparametrically modeled variables. The work

  11. Smart Management in Effective Schools: Effective Management Configurations in General and Vocational Education in the Netherlands

    Science.gov (United States)

    Hofman, W. H. Adriaan; Hofman, Roelande H.

    2011-01-01

    Purpose: In this study the authors focus on different (configurations of) leadership or management styles in schools for general and vocational education. Findings: Using multilevel (students and schools) analyses, strong differences in effective management styles between schools with different student populations were observed. Conclusions: The…

  12. The generalized Abel-Plana formula. Applications to Bessel functions and Casimir effect

    International Nuclear Information System (INIS)

    Saharian, A.A.; Institute of Applied Problems in Physics NAS RA, Yerevan; Abdus Salam International Centre for Theoretical Physics, Trieste

    2000-02-01

    One of the most efficient methods to obtain the vacuum expectation values for the physical observables in the Casimir effect is based on using the Abel-Plana summation formula. This allows us to derive the regularized quantities in a manifestly cutoff independent way and present them in the form of strongly convergent integrals. However, the application of Abel-Plana formula, in its usual form, is restricted by simple geometries when the eigenmodes have a simple dependence on quantum numbers. The author generalized the Abel-Plana formula which essentially enlarges its application range. Based on this generalization, formulae have been obtained for various types of series over the zeros of some combinations of Bessel functions and for integrals involving these functions. It has been shown that these results generalize the special cases existing in literature. Further, the derived summation formulae have been used to summarize series arising in the mode summation approach to the Casimir effect for spherically and cylindrically symmetric boundaries. This allows us to extract the divergent parts from the vacuum expectation values for the local physical observables in a manifestly cutoff independent way. The present paper reviews these results. Some new considerations are also added. (author)

  13. Perceptions of teachers' general and informational feedback and intrinsic motivation in physical education: two-year effects.

    Science.gov (United States)

    Koka, Andre; Hein, Vello

    2006-10-01

    Relative change or stability of perceived positive general feedback and perceived informational feedback and their influence on students' intrinsic motivation in physical education over two years were examined. 302 students, ages 11 to 15 years, responded to the Perception of Teacher's Feedback questionnaire. Two years later, these students filled out the questionnaire again, along with a modified version of the Sport Motivation Scale. Analysis showed that both types of perceived feedback exhibited moderate stability over the two years. Perceived positive general feedback demonstrated a significant direct effect on students' intrinsic motivation measured concurrently in physical education. Further, fixing to zero the effect of perceived positive general feedback on intrinsic motivation measured concurrently, an effect emerged over the two years.

  14. Analytic theory of curvature effects for wave problems with general boundary conditions

    DEFF Research Database (Denmark)

    Willatzen, Morten; Gravesen, Jens; Voon, L. C. Lew Yan

    2010-01-01

    A formalism based on a combination of differential geometry and perturbation theory is used to obtain analytic expressions for confined eigenmode changes due to general curvature effects. In cases of circular-shaped and helix-shaped structures, where alternative analytic solutions can be found......, the perturbative solution is shown to yield the same result. The present technique allows the generalization of earlier results to arbitrary boundary conditions. The power of the method is illustrated using examples based on Maxwell’s and Schrödinger’s equations for applications in photonics and nanoelectronics....

  15. Why are predictions of general relativity theory for gravitational effects non-unique?

    International Nuclear Information System (INIS)

    Loskutov, Yu.M.

    1990-01-01

    Reasons of non-uniqueness of predictions of the general relativity theory (GRT) for gravitational effects are analyzed in detail. To authors' opinion, the absence of comparison mechanism of curved and plane metrics is the reason of non-uniqueness

  16. Analysis of General Power Counting Rules in Effective Field Theory

    CERN Document Server

    Gavela, B M; Manohar, A V; Merlo, L

    2016-01-01

    We derive the general counting rules for a quantum effective field theory (EFT) in $\\mathsf{d}$ dimensions. The rules are valid for strongly and weakly coupled theories, and predict that all kinetic energy terms are canonically normalized. They determine the energy dependence of scattering cross sections in the range of validity of the EFT expansion. The size of cross sections is controlled by the $\\Lambda$ power counting of EFT, not by chiral counting, even for chiral perturbation theory ($\\chi$PT). The relation between $\\Lambda$ and $f$ is generalized to $\\mathsf{d}$ dimensions. We show that the naive dimensional analysis $4\\pi$ counting is related to $\\hbar$ counting. The EFT counting rules are applied to $\\chi$PT, to Standard Model EFT and to the non-trivial case of Higgs EFT, which combines the $\\Lambda$ and chiral counting rules within a single theory.

  17. Effects of offshore wind farms on marine wildlife-a generalized impact assessment

    DEFF Research Database (Denmark)

    Bergstrom, L.; Kautsky, L.; Malm, T.

    2014-01-01

    study synthesizes the current state of understanding on the effects of offshore wind farms on marine wildlife, in order to identify general versus local conclusions in published studies. The results were translated into a generalized impact assessment for coastal waters in Sweden, which covers a range......, and level of certainty. Research on the environmental effects of offshore wind farms has gone through a rapid maturation and learning process, with the bulk of knowledge being developed within the past ten years. The studies showed a high level of consensus with respect to the construction phase, indicating...... that potential impacts on marine life should be carefully considered in marine spatial planning. Potential impacts during the operational phase were more locally variable, and could be either negative or positive depending on biological conditions as well as prevailing management goals. There was paucity...

  18. Randomized controlled trial of the effect of medical audit on AIDS prevention in general practice

    DEFF Research Database (Denmark)

    Sandbæk, Annelli

    1999-01-01

    OBJECTIVE: We aimed to evaluate the effect of a medical audit on AIDS prevention in general practice. METHODS: We conducted a prospective randomized controlled study performed as 'lagged intervention'. At the time of comparison, the intervention group had completed 6 months of audit including...... of such consultations initiated by the GPs. CONCLUSIONS: Medical audit had no observed effect on AIDS prevention in general practice. Udgivelsesdato: 1999-Oct...... a primary activity registration, feedback of own data and a meeting with colleagues and experts, and had received brief summaries of the meetings and reminders about the project (a full 'audit circle'). The participants were from general practices in Copenhagen and the Counties of Funen and Vejle, Denmark...

  19. Effective Hamiltonians, two level systems, and generalized Maxwell-Bloch equations

    International Nuclear Information System (INIS)

    Sczaniecki, L.

    1981-02-01

    A new method is proposed involving a canonical transformation leading to the non-secular part of time-independent perturbation calculus. The method is used to derive expressions for effective Shen-Walls Hamiltonians which, taken in the two-level approximation and on the inclusion of non-Hamiltonian terms into the dynamics of the system, lead to generalized Maxwell-Bloch equations. The rotating wave approximation is written anew within the framework of our formalism. (author)

  20. Size effects in two-dimensional Voronoi foams : A comparison between generalized continua and discrete models

    NARCIS (Netherlands)

    Tekoglu, Cihan; Onck, Patrick R.

    2008-01-01

    In view of size effects in cellular solids, we critically compare the analytical results of generalized continuum theories with the computation a I results of discrete models. Representatives are studied from two classes of generalized continuum theories: the strain divergence theory from the class

  1. Generalized effective potential in nonlinear theories of the 4-th order

    International Nuclear Information System (INIS)

    Ananikyan, N.S.; Savvidy, G.K.

    1980-01-01

    By means of the Legendre transformations in the framework of nonlinear theories of the 4-th order a generalized effective potential GITA(phi, G, H, S) is constructed. It depends on PHI, a possible expectation value of the quantum field; on G, H, possible expectation values of the 2- a.nd 3-point connected Green functions and on S= a possible expectation value of the classical action. The expansion for the functional GITA(phi, G, H, S) is obtained, which is similar to the loop expansion for the effective action GITA(phi)

  2. Obtaining the general forms of the effective coefficients of laminate magneto-electro - elastic

    International Nuclear Information System (INIS)

    Cabañas, J. H.; Otero, A.; Castillero, B.; Rodríguez, R.

    2008-01-01

    In this work using the asymptotic homogenization method obtained general expressions for the calculation of the effective characteristics of magnetoelectro-elastic laminates with layers of any symmetry. You will reach an array of auxiliary functions for determining the effective coefficients for a serial connection and displays a result similar to the case of parallel connection.

  3. Effect of mailed reminders on the response rate in surveys among patients in general practice

    DEFF Research Database (Denmark)

    Wensing, M; Mainz, Jan; Kramme, O

    1999-01-01

    Randomized trials were performed in Denmark and The Netherlands to determine the effect of mailed reminders on the response rate in surveys among patients in general practice. In both countries, general practitioners handed out questionnaires to 200 adult patients who came to visit them. An inter...

  4. Explaining Compound Generalization in Associative and Causal Learning Through Rational Principles of Dimensional Generalization

    Science.gov (United States)

    Soto, Fabian A.; Gershman, Samuel J.; Niv, Yael

    2014-01-01

    How do we apply learning from one situation to a similar, but not identical, situation? The principles governing the extent to which animals and humans generalize what they have learned about certain stimuli to novel compounds containing those stimuli vary depending on a number of factors. Perhaps the best studied among these factors is the type of stimuli used to generate compounds. One prominent hypothesis is that different generalization principles apply depending on whether the stimuli in a compound are similar or dissimilar to each other. However, the results of many experiments cannot be explained by this hypothesis. Here we propose a rational Bayesian theory of compound generalization that uses the notion of consequential regions, first developed in the context of rational theories of multidimensional generalization, to explain the effects of stimulus factors on compound generalization. The model explains a large number of results from the compound generalization literature, including the influence of stimulus modality and spatial contiguity on the summation effect, the lack of influence of stimulus factors on summation with a recovered inhibitor, the effect of spatial position of stimuli on the blocking effect, the asymmetrical generalization decrement in overshadowing and external inhibition, and the conditions leading to a reliable external inhibition effect. By integrating rational theories of compound and dimensional generalization, our model provides the first comprehensive computational account of the effects of stimulus factors on compound generalization, including spatial and temporal contiguity between components, which have posed longstanding problems for rational theories of associative and causal learning. PMID:25090430

  5. Randomized controlled trial of the effect of medical audit on AIDS prevention in general practice

    DEFF Research Database (Denmark)

    Sandbæk, Annelli

    1999-01-01

    OBJECTIVE: We aimed to evaluate the effect of a medical audit on AIDS prevention in general practice. METHODS: We conducted a prospective randomized controlled study performed as 'lagged intervention'. At the time of comparison, the intervention group had completed 6 months of audit including a p...... of such consultations initiated by the GPs. CONCLUSIONS: Medical audit had no observed effect on AIDS prevention in general practice. Udgivelsesdato: 1999-Oct......OBJECTIVE: We aimed to evaluate the effect of a medical audit on AIDS prevention in general practice. METHODS: We conducted a prospective randomized controlled study performed as 'lagged intervention'. At the time of comparison, the intervention group had completed 6 months of audit including....... One hundred and thirty-three GPs completed the project. The main outcome measures were the number of consultations involving AIDS prevention and the number of talks about AIDS initiated by the GP, and some elements of the content were registered on a chart. RESULTS: No statistically significant...

  6. A powerful parent-of-origin effects test for qualitative traits on X chromosome in general pedigrees.

    Science.gov (United States)

    Zou, Qi-Lei; You, Xiao-Ping; Li, Jian-Long; Fung, Wing Kam; Zhou, Ji-Yuan

    2018-01-05

    Genomic imprinting is one of the well-known epigenetic factors causing the association between traits and genes, and has generally been examined by detecting parent-of-origin effects of alleles. A lot of methods have been proposed to test for parent-of-origin effects on autosomes based on nuclear families and general pedigrees. Although these parent-of-origin effects tests on autosomes have been available for more than 15 years, there has been no statistical test developed to test for parent-of-origin effects on X chromosome, until the parental-asymmetry test on X chromosome (XPAT) and its extensions were recently proposed. However, these methods on X chromosome are only applicable to nuclear families and thus are not suitable for general pedigrees. In this article, we propose the pedigree parental-asymmetry test on X chromosome (XPPAT) statistic to test for parent-of-origin effects in the presence of association, which can accommodate general pedigrees. When there are missing genotypes in some pedigrees, we further develop the Monte Carlo pedigree parental-asymmetry test on X chromosome (XMCPPAT) to test for parent-of-origin effects, by inferring the missing genotypes given the observed genotypes based on a Monte Carlo estimation. An extensive simulation study has been carried out to investigate the type I error rates and the powers of the proposed tests. Our simulation results show that the proposed methods control the size well under the null hypothesis of no parent-of-origin effects. Moreover, XMCPPAT substantially outperforms the existing tests and has a much higher power than XPPAT which only uses complete nuclear families (with both parents) from pedigrees. We also apply the proposed methods to analyze rheumatoid arthritis data for their practical use. The proposed XPPAT and XMCPPAT test statistics are valid and powerful in detecting parent-of-origin effects on X chromosome for qualitative traits based on general pedigrees and thus are recommended.

  7. The Long-Term Effects of Childhood Music Instruction on Intelligence and General Cognitive Abilities

    Science.gov (United States)

    Costa-Giomi, Eugenia

    2015-01-01

    This article reviews research on the effects of music instruction on general cognitive abilities. The review of more than 75 reports shows (1) the consistency in results pertaining to the short-term effects of music instruction on cognitive abilities and the lack of clear evidence on the long-term effects on intelligence; (2) the complex nature of…

  8. The Testing Effect: An Intervention on Behalf of Low-Skilled Comprehenders in General Chemistry

    Science.gov (United States)

    Pyburn, Daniel T.; Pazicni, Samuel; Benassi, Victor A.; Tappin, Elizabeth M.

    2014-01-01

    Past work has demonstrated that language comprehension ability correlates with general chemistry course performance with medium effect sizes. We demonstrate here that language comprehension's strong cognitive grounding can be used to inform effective and equitable pedagogies, namely, instructional interventions that differentially aid low-skilled…

  9. Relative Effectiveness of DRO and Self-Monitoring in a General Education Classroom

    Science.gov (United States)

    Vance, Michael J.; Gresham, Frank M.; Dart, Evan H.

    2012-01-01

    This manuscript describes a research project designed to examine the relative effectiveness of a two non-function-based interventions (differential reinforcement of other behavior and self- monitoring) for decreasing problem behavior in a general education classroom for three students whose problem behaviors were hypothesized to be functionally…

  10. Volunteering and health benefits in general adults: cumulative effects and forms.

    Science.gov (United States)

    Yeung, Jerf W K; Zhang, Zhuoni; Kim, Tae Yeun

    2017-07-11

    Although the health benefits of volunteering have been well documented, no research has examined its cumulative effects according to other-oriented and self-oriented volunteering on multiple health outcomes in the general adult public. This study examined other-oriented and self-oriented volunteering in cumulative contribution to health outcomes (mental and physical health, life satisfaction, social well-being and depression). Data were drawn from the Survey of Texas Adults 2004, which contains a statewide population-based sample of adults (n = 1504). Multivariate linear regression and Wald test of parameters equivalence constraint were used to test the relationships. Both forms of volunteering were significantly related to better health outcomes (odds ratios = 3.66% to 11.11%), except the effect of self-oriented volunteering on depression. Other-oriented volunteering was found to have better health benefits than did self-volunteering. Volunteering should be promoted by public health, education and policy practitioners as a kind of healthy lifestyle, especially for the social subgroups of elders, ethnic minorities, those with little education, single people, and unemployed people, who generally have poorer health and less participation in volunteering.

  11. Do general practices adhere to organizational guidelines for effective cervical cancer screening?

    NARCIS (Netherlands)

    Hermens, R P; Hak, E; Hulscher, M E; Mulder, J; Braspenning, J C; Grol, R P

    BACKGROUND: Well-organized cervical screening has been shown to be effective in the reduction of both morbidity and mortality from cancer of the uterine cervix. In The Netherlands, the GP plays an important role in the cervical screening. The question is whether the general practices are able to

  12. Generalized infimum and sequential product of quantum effects

    International Nuclear Information System (INIS)

    Li Yuan; Sun Xiuhong; Chen Zhengli

    2007-01-01

    The quantum effects for a physical system can be described by the set E(H) of positive operators on a complex Hilbert space H that are bounded above by the identity operator I. For A, B(set-membership sign)E(H), the operation of sequential product A(convolution sign)B=A 1/2 BA 1/2 was proposed as a model for sequential quantum measurements. A nice investigation of properties of the sequential product has been carried over [Gudder, S. and Nagy, G., 'Sequential quantum measurements', J. Math. Phys. 42, 5212 (2001)]. In this note, we extend some results of this reference. In particular, a gap in the proof of Theorem 3.2 in this reference is overcome. In addition, some properties of generalized infimum A sqcap B are studied

  13. The Effects of Clickers and Online Homework on Students' Achievement in General Chemistry

    Science.gov (United States)

    Gebru, Misganaw T.

    2012-01-01

    Retention of an introductory general chemistry course material is vital for student success in future chemistry and chemistry-related courses. This study investigated the effects of clickers versus online homework on students' long-term content retention, examined the effectiveness of online homework versus no graded homework on…

  14. General theory for environmental effects on (vertical) electronic excitation energies.

    Science.gov (United States)

    Schwabe, Tobias

    2016-10-21

    Almost 70 years ago, the first theoretical model for environmental effects on electronic excitation energies has been derived. Since then, several different interpretations and refined models have been proposed for the perichromic shift of a chromophore due to its surrounding medium. Some of these models are contradictory. Here, the contributing terms are derived within the framework of long-range perturbation theory with the least approximations so far. The derivation is based on a state-specific interpretation of the interaction energies and all terms can be identified with individual properties of either the chromophore or the surroundings, respectively. Further, the much debated contribution due to transition moments coupled to the environment can be verified in the form of a non-resonant excitonic coupling to the dynamic polarizabilities in the environment. These general insights should clarify discussions and interpretations of environmental effects on electronic excitations and should foster the development of new models for the computation of these effects.

  15. General practitioners' perceptions of the effectiveness of medical interventions: an exploration of underlying constructs

    Directory of Open Access Journals (Sweden)

    Marteau Theresa M

    2010-02-01

    Full Text Available Abstract Background Many interventions shown to be effective through clinical trials are not readily implemented in clinical practice. Unfortunately, little is known regarding how clinicians construct their perceptions of the effectiveness of medical interventions. This study aims to explore general practitioners' perceptions of the nature of 'effectiveness'. Methods The design was qualitative in nature using the repertory grid technique to elicit the constructs underlying the perceived effectiveness of a range of medical interventions. Eight medical interventions were used as stimuli (diclophenac to reduce acute pain, cognitive behaviour therapy to treat depression, weight loss surgery to achieve weight loss, diet and exercise to prevent type 2 diabetes, statins to prevent heart disease, stopping smoking to prevent heart disease, nicotine replacement therapy to stop smoking, and stop smoking groups to stop smoking. The setting involved face-to-face interviews followed by questionnaires in London Primary Care Trusts. Participants included a random sample of 13 general practitioners. Results Analysis of the ratings showed that the constructs clustered around two dimensions: low patient effort versus high patient effort (dimension one, and small impact versus large impact (dimension two. Dimension one represented constructs such as 'success requires little motivation', 'not a lifestyle intervention', and 'health-care professional led intervention'. Dimension two represented constructs such as 'weak and/or minimal evidence of effectiveness', 'small treatment effect for users', 'a small proportion of users will benefit' and 'not cost-effective'. Constructs within each dimension were closely related. Conclusions General practitioners judged the effectiveness of medical interventions by considering two broad dimensions: the extent to which interventions involve patient effort, and the size of their impact. The latter is informed by trial evidence, but

  16. Effects of offshore wind farms on marine wildlife—a generalized impact assessment

    Science.gov (United States)

    Bergström, Lena; Kautsky, Lena; Malm, Torleif; Rosenberg, Rutger; Wahlberg, Magnus; Åstrand Capetillo, Nastassja; Wilhelmsson, Dan

    2014-03-01

    Marine management plans over the world express high expectations to the development of offshore wind energy. This would obviously contribute to renewable energy production, but potential conflicts with other usages of the marine landscape, as well as conservation interests, are evident. The present study synthesizes the current state of understanding on the effects of offshore wind farms on marine wildlife, in order to identify general versus local conclusions in published studies. The results were translated into a generalized impact assessment for coastal waters in Sweden, which covers a range of salinity conditions from marine to nearly fresh waters. Hence, the conclusions are potentially applicable to marine planning situations in various aquatic ecosystems. The assessment considered impact with respect to temporal and spatial extent of the pressure, effect within each ecosystem component, and level of certainty. Research on the environmental effects of offshore wind farms has gone through a rapid maturation and learning process, with the bulk of knowledge being developed within the past ten years. The studies showed a high level of consensus with respect to the construction phase, indicating that potential impacts on marine life should be carefully considered in marine spatial planning. Potential impacts during the operational phase were more locally variable, and could be either negative or positive depending on biological conditions as well as prevailing management goals. There was paucity in studies on cumulative impacts and long-term effects on the food web, as well as on combined effects with other human activities, such as the fisheries. These aspects remain key open issues for a sustainable marine spatial planning.

  17. Generalized herd effects and vaccine evaluation: impact of live influenza vaccine on off-target bacterial colonisation.

    Science.gov (United States)

    Mina, Michael J

    2017-06-01

    Interactions between pathogens and commensal microbes are major contributors to health and disease. Infectious diseases however are most often considered independent, viewed within a one-host one-pathogen paradigm and, by extension, the interventions used to treat and prevent them are measured and evaluated within this same paradigm. Vaccines, especially live vaccines, by stimulating immune responses or directly interacting with other microbes can alter the environment in which they act, with effects that span across pathogen species. Live attenuated infl uenza vaccines for example, while safe, increase upper respiratory tract bacterial carriage density of important human commensal pathogens like Streptococcus pneumoniae and Staphylococcus aureus. Further, by altering the ecological niche and dynamics of phylogenetically distinct microbes within the host, vaccines may unintentionally affect transmission of non-vaccine targeted pathogens. Thus, vaccine effects may span across species and across scales, from the individual to the population level. In keeping with traditional vaccine herd-effects that indirectly protect even unvaccinated individuals by reducing population prevalence of vaccine-targeted pathogens, we call these cross-species cross-scale effects "generalized herd-effects". As opposed to traditional herd-effects, "generalized" relaxes the assumption that the effect occurs at the level of the vaccine-target pathogen and "herd effect" implies, as usual, that the effects indirectly impact the population at large, including unvaccinated bystanders. Unlike traditional herd-effects that decrease population prevalence of the vaccine-target, generalized herd-effects may decrease or increase prevalence and disease by the off-target pathogen. LAIV, for example, by increasing pneumococcal density in the upper respiratory tract of vaccine recipients, especially children, may increase pneumococcal transmission and prevalence, leading to excess pneumococcal invasive

  18. Prototype effect and the persuasiveness of generalizations

    OpenAIRE

    Dahlman, Christian; Sarwar, Farhan; Bååth, Rasmus; Wahlberg, Lena; Sikström, Sverker

    2015-01-01

    An argument that makes use of a generalization activates the prototype for the category used in the generalization. We conducted two experiments that investigated how the activation of the prototype affects the persuasiveness of the argument. The results of the experiments suggest that the features of the prototype overshadow and partly overwrite the actual facts of the case. The case is, to some extent, judged as if it had the features of the prototype instead of the features it actually ...

  19. Comments on general gauge mediation

    International Nuclear Information System (INIS)

    Intriligator, Kenneth; Sudano, Matthew

    2008-01-01

    There has been interest in generalizing models of gauge mediation of supersymmetry breaking. As shown by Meade, Seiberg, and Shih (MSS), the soft masses of general gauge mediation can be expressed in terms of the current two-point functions of the susy-breaking sector. We here give a simple extension of their result which provides, for general gauge mediation, the full effective potential for squark pseudo-D-flat directions. The effective potential reduces to the sfermion soft masses near the origin, and the full potential, away from the origin, can be useful for cosmological applications. We also generalize the soft masses and effective potential to allow for general gauge mediation by Higgsed gauge groups. Finally, we discuss general gauge mediation in the limit of small F-terms, and how the results of MSS connect with the analytic continuation in superspace results, based on a spurion analysis.

  20. Generalized Predictive Control and Neural Generalized Predictive Control

    Directory of Open Access Journals (Sweden)

    Sadhana CHIDRAWAR

    2008-12-01

    Full Text Available As Model Predictive Control (MPC relies on the predictive Control using a multilayer feed forward network as the plants linear model is presented. In using Newton-Raphson as the optimization algorithm, the number of iterations needed for convergence is significantly reduced from other techniques. This paper presents a detailed derivation of the Generalized Predictive Control and Neural Generalized Predictive Control with Newton-Raphson as minimization algorithm. Taking three separate systems, performances of the system has been tested. Simulation results show the effect of neural network on Generalized Predictive Control. The performance comparison of this three system configurations has been given in terms of ISE and IAE.

  1. Effects of offshore wind farms on marine wildlife—a generalized impact assessment

    International Nuclear Information System (INIS)

    Bergström, Lena; Kautsky, Lena; Malm, Torleif; Åstrand Capetillo, Nastassja; Rosenberg, Rutger; Wahlberg, Magnus; Wilhelmsson, Dan

    2014-01-01

    Marine management plans over the world express high expectations to the development of offshore wind energy. This would obviously contribute to renewable energy production, but potential conflicts with other usages of the marine landscape, as well as conservation interests, are evident. The present study synthesizes the current state of understanding on the effects of offshore wind farms on marine wildlife, in order to identify general versus local conclusions in published studies. The results were translated into a generalized impact assessment for coastal waters in Sweden, which covers a range of salinity conditions from marine to nearly fresh waters. Hence, the conclusions are potentially applicable to marine planning situations in various aquatic ecosystems. The assessment considered impact with respect to temporal and spatial extent of the pressure, effect within each ecosystem component, and level of certainty. Research on the environmental effects of offshore wind farms has gone through a rapid maturation and learning process, with the bulk of knowledge being developed within the past ten years. The studies showed a high level of consensus with respect to the construction phase, indicating that potential impacts on marine life should be carefully considered in marine spatial planning. Potential impacts during the operational phase were more locally variable, and could be either negative or positive depending on biological conditions as well as prevailing management goals. There was paucity in studies on cumulative impacts and long-term effects on the food web, as well as on combined effects with other human activities, such as the fisheries. These aspects remain key open issues for a sustainable marine spatial planning. (paper)

  2. Effect of Formative Quizzes on Teacher Candidates’ Learning in General Chemistry

    OpenAIRE

    Yalaki, Yalcin; Bayram, Zeki

    2015-01-01

    Formative assessment or assessment for learning is one of the most emphasized educational innovations around the world. Two of the common strategies that could be used in formative assessment are use of summative tests for formative purposes and comment only marking. We utilized these strategies in the form of formative quizzes in a general chemistry course and measured its effect on students’ learning. The results of our weak-experimental design, which was conducted with 124 pre-service elem...

  3. The subliminal mere exposure effect does not generalize to structurally related stimuli.

    Science.gov (United States)

    Newell, Ben R; Bright, James E H

    2003-03-01

    R.F. Bornstein (1994) questioned whether subliminal mere exposure effects might generalize to structurally related stimuli, thereby providing evidence for the existence of implicit learning. Two experiments examined this claim using letter string stimuli constructed according to the rules of an artificial grammar. Experiment 1 demonstrated that brief, masked exposure to grammatical strings impaired recognition but failed to produce a mere exposure effect on novel structurally related strings seen at test. Experiment 2 replicated this result but also demonstrated that a reliable mere exposure effect could be obtained, provided the same grammatical strings were presented at test. The results suggest that the structural relationship between training and test items prevents the mere exposure effect when participants are unaware of the exposure status of stimuli, and therefore provide no evidence for the existence of implicit learning.

  4. Generalized graph manifolds and their effective recognition

    International Nuclear Information System (INIS)

    Matveev, S V

    1998-01-01

    A generalized graph manifold is a three-dimensional manifold obtained by gluing together elementary blocks, each of which is either a Seifert manifold or contains no essential tori or annuli. By a well-known result on torus decomposition each compact three-dimensional manifold with boundary that is either empty or consists of tori has a canonical representation as a generalized graph manifold. A short simple proof of the existence of a canonical representation is presented and a (partial) algorithm for its construction is described. A simple hyperbolicity test for blocks that are not Seifert manifolds is also presented

  5. Patient education about cough: effect on the consulting behaviour of general practice patients.

    Science.gov (United States)

    Rutten, G; Van Eijk, J; Beek, M; Van der Velden, H

    1991-07-01

    The aim of this general practice study was to examine how the consulting behaviour of patients with a cough was affected when the tasks and responsibilities of patients, practice nurses and general practitioners were reorganized. In four 'average' single-handed general practices the effects on the consulting behaviour of patients of a rational practice policy on cough and the provision of systematic patient education on cough were compared with patient behaviour in four matched control practices. Changes of behaviour were measured in 548 patients who consulted for cough at least twice, in two successive autumn-winter periods. Significantly more patients in the experimental practice changed their behaviour to follow the practice guidelines than did patients in the control practices (56% versus 30%, P less than 0.001). The proportion of patients who continued to consult in the approved manner was greater among patients receiving intervention (66% versus 29%, P less than 0.001). This was equally true for patients who had suffered less than four episodes of cough or more than four episodes. The more often the patients received the education, the more effective it was. All patients who consulted the general practitioner for cough during the first autumn-winter period filled in a cough diary during the second period. From this it appeared that the intervention did not result in patients delaying consultation when they had a cough lasting longer than three weeks or one with 'serious' symptoms. It would appear that a rational practice policy and the provision of patient education can stimulate patients to modify their consulting behaviour. This could result in a reduction in the costs of health care.

  6. Effects of general relativity on glitch amplitudes and pulsar mass upper bounds

    Science.gov (United States)

    Antonelli, M.; Montoli, A.; Pizzochero, P. M.

    2018-04-01

    Pinning of vortex lines in the inner crust of a spinning neutron star may be the mechanism that enhances the differential rotation of the internal neutron superfluid, making it possible to freeze some amount of angular momentum which eventually can be released, thus causing a pulsar glitch. We investigate the general relativistic corrections to pulsar glitch amplitudes in the slow-rotation approximation, consistently with the stratified structure of the star. We thus provide a relativistic generalization of a previous Newtonian model that was recently used to estimate upper bounds on the masses of glitching pulsars. We find that the effect of general relativity on the glitch amplitudes obtained by emptying the whole angular momentum reservoir is less than 30 per cent. Moreover, we show that the Newtonian upper bounds on the masses of large glitchers obtained from observations of their maximum recorded event differ by less than a few percent from those calculated within the relativistic framework. This work can also serve as a basis to construct more sophisticated models of angular momentum reservoir in a relativistic context: in particular, we present two alternative scenarios for macroscopically rigid and slack pinned vortex lines, and we generalize the Feynman-Onsager relation to the case when both entrainment coupling between the fluids and a strong axisymmetric gravitational field are present.

  7. Distributing learning over time: the spacing effect in children's acquisition and generalization of science concepts.

    Science.gov (United States)

    Vlach, Haley A; Sandhofer, Catherine M

    2012-01-01

    The spacing effect describes the robust finding that long-term learning is promoted when learning events are spaced out in time rather than presented in immediate succession. Studies of the spacing effect have focused on memory processes rather than for other types of learning, such as the acquisition and generalization of new concepts. In this study, early elementary school children (5- to 7-year-olds; N = 36) were presented with science lessons on 1 of 3 schedules: massed, clumped, and spaced. The results revealed that spacing lessons out in time resulted in higher generalization performance for both simple and complex concepts. Spaced learning schedules promote several types of learning, strengthening the implications of the spacing effect for educational practices and curriculum. © 2012 The Authors. Child Development © 2012 Society for Research in Child Development, Inc.

  8. Social-cognitive remediation in schizophrenia: generalization of effects of the Training of Affect Recognition (TAR).

    Science.gov (United States)

    Wölwer, Wolfgang; Frommann, Nicole

    2011-09-01

    In the last decade, several social cognitive remediation programs have been developed for use in schizophrenia. Though existing evidence indicates that such programs can improve social cognition, which is essential for successful social functioning, it remains unclear whether the improvements generalize to social cognitive domains not primarily addressed by the intervention and whether the improved test performance transfers into everyday social functioning. The present study investigated whether, beyond its known effects on facial affect recognition, the Training of Affect Recognition (TAR) has effects on prosodic affect recognition, theory of mind (ToM) performance, social competence in a role-play task, and more general social and occupational functioning. Thirty-eight inpatients with a diagnosis of schizophrenia or schizoaffective disorder were randomly assigned to 6 weeks of treatment with the TAR--primarily targeted at facial affect recognition-or Cognitive Remediation Training (CRT)--primarily targeted at neurocognition. Intention-to-treat analyses found significantly larger pre-post improvements with TAR than with CRT in prosodic affect recognition, ToM, and social competence and a trend effect in global social functioning. However, the effects on ToM and social competence were no longer significant in the smaller group of patients who completed treatment according to protocol. Results suggest that TAR effects generalize to other social cognitive domains not primarily addressed. TAR may also enhance social skills and social functioning, although this has to be confirmed. Results are discussed with regard to the need to improve functional outcome in schizophrenia against the background of current evidence from other social cognitive remediation approaches.

  9. Neighborhood-Specific and General Social Support: Which Buffers the Effect of Neighborhood Disorder on Depression?

    Science.gov (United States)

    Kim, Joongbaeck; Ross, Catherine E.

    2009-01-01

    Is neighborhood-specific social support the most effective type of social support for buffering the effect of neighborhood disorder on depression? Matching theory suggests that it is. The authors extend the research on neighborhood disorder and adult depression by showing that individuals who have higher levels of both general and…

  10. Examining the Effects of Reflective Journals on Pre-Service Science Teachers' General Chemistry Laboratory Achievement

    Science.gov (United States)

    Cengiz, Canan; Karatas, Faik Özgür

    2015-01-01

    The general chemistry laboratory is an appropriate place for learning chemistry well. It is also effective for stimulating higher-order thinking skills, including reflective thinking, a skill that is crucial for science teaching as well as learning. This study aims to examine the effects of feedback-supported reflective journal-keeping activities…

  11. General and Specific Effects of Lexicon in Grammar: Determiner and Object Pronoun Omissions in Child Spanish

    Science.gov (United States)

    Perez-Leroux, Ana Teresa; Castilla-Earls, Anny Patricia; Brunner, Jerry

    2012-01-01

    Purpose: This study explores the hypothesis that vocabulary growth can have 2 types of effects in morphosyntactic development. One is a general effect, where vocabulary growth globally determines utterance complexity, defined in terms of sentence length and rates of subordination. There are also specific effects, where vocabulary size has a…

  12. Cardiovascular effects of oesophageal dilation under general anaesthesia

    DEFF Research Database (Denmark)

    Jakobsen, C H; Rasmussen, V; Rosenberg, J

    1999-01-01

    , but was not associated with the actual time of oesophageal distension. Thus, all cases of myocardial ischaemia were related to the time of extubation. No lasting complications were seen, and all patients could be discharged a maximum of 24 hours after the procedure. Pneumatic dilation of the oesophagus under general......Myocardial ischaemia and cardiac arrhythmias may occur during oesophageal dilation under conscious sedation, but no prospective data exist regarding dilation under general anaesthesia. We have studied the haemodynamic and electrocardiographic changes during routine oesophageal balloon dilation...... the procedure. Four patients developed significant hypotension at the time of balloon inflation with two patients requiring medical intervention to re-establish sufficient cardiovascular function. Tachycardia and ST-deviation occurred in four and three patients, respectively, during the general anaesthesia...

  13. Investigating the effect of work stress, general health quality, organizational intelligence and job satisfaction on employee performance

    Directory of Open Access Journals (Sweden)

    Masoud Samadzadeh

    2013-12-01

    Full Text Available During the past few years, there have been tremendous efforts on measuring the effects of different factors such as work stress, general heath quality, etc. on performance of employees. In this paper, we present an empirical investigation to study the effects of work stress, general health, organizational intelligence and job satisfaction on employee performance. The proposed study of this paper uses two questionnaires where one is associated with general heath quality (GHQ with 20 questions and the other one consists of 12 questions, which is associated with work stress. The study chooses a sample of 144 employees from 222 people who worked for one of Islamic Azad University in Iran. Cronbach alphas for work stress, general health, organizational intelligence, job satisfaction and organizational performance are 0.911, 0.895, 0.795, 0.863 and, 0.864, respectively. The results indicate that job satisfaction has the highest influence on organizational performance followed by other factors.

  14. The generalized Schwinger-DeWitt technique and the unique effective action in quantum gravity

    International Nuclear Information System (INIS)

    Barvinsky, A.O.; Vilkovisky, G.A.

    1983-01-01

    We consider the one-loop approximation to the recently proposed unique effective action in gauge theory. The Schwinger-DeWitt technique is generalized and applied to the computation of the unique gravitational counterterms. The issue of asymptotic freedom is reexamined. (orig.)

  15. A general X-ray fluorescence spectrometric technique based on simple corrections for matrix effects

    International Nuclear Information System (INIS)

    Kruidhof, H.

    1978-01-01

    The method reported, which is relatively simple and generally applicable for most materials, involves a combination of borax fusion with matrix effect corrections. The latter are done with algorithms, which are derived from the intensity formulae, together with empirical coefficients. (Auth.)

  16. On the generalized Hartman effect for symmetric double-barrier point potentials

    International Nuclear Information System (INIS)

    Lee, Molly A; Manzoni, Luiz A; Nyquist, Erik A; Lunardi, José T

    2015-01-01

    We consider the scattering of a non-relativistic particle by a symmetrical arrangement of two identical barriers in one-dimension, with the barriers given by the well-known four-parameter family of point interactions. We calculate the phase time and the stationary Salecker-Wigner-Peres clock time for the particular cases of a double δ and a double δ' barrier and investigate the off-resonance behavior of these time scales in the limit of opaque barriers, addressing the question of emergence of the generalized Hartman effect

  17. The effective action in (2+1)-dimensional gravity and generalized BF topological field theory

    Energy Technology Data Exchange (ETDEWEB)

    Birmingham, D. (Theory Div., CERN, Geneva (Switzerland)); Gibbs, R.; Mokhtari, S. (Physics Dept., Louisiana Tech Univ., Ruston, LA (United States))

    1991-07-11

    The one-loop off-shell effective action is studied for the case of generalized BF theories in three dimensions, including, for example, (2 + 1)-dimensional gravity with a cosmological constant. The phase contribution to the effective action, originating from the {eta}-function of a particular first order operator, is calculated using a momentum space technique. It is found that the {eta}-function is proportional to the classical action. (orig.).

  18. The effective action in (2+1)-dimensional gravity and generalized BF topological field theory

    International Nuclear Information System (INIS)

    Birmingham, D.; Gibbs, R.; Mokhtari, S.

    1991-01-01

    The one-loop off-shell effective action is studied for the case of generalized BF theories in three dimensions, including, for example, (2 + 1)-dimensional gravity with a cosmological constant. The phase contribution to the effective action, originating from the η-function of a particular first order operator, is calculated using a momentum space technique. It is found that the η-function is proportional to the classical action. (orig.)

  19. Magnitude of effects in clinical trials published in high-impact general medical journals.

    Science.gov (United States)

    Siontis, Konstantinos C M; Evangelou, Evangelos; Ioannidis, John P A

    2011-10-01

    Prestigious journals select for publication studies that are considered most important and informative. We aimed to examine whether high-impact general (HIG) medical journals systematically demonstrate more favourable results for experimental interventions compared with the rest of the literature. We scrutinized systematic reviews of the Cochrane Database (Issue 4, 2009) and meta-analyses published in four general journals (2008-09). Eligible articles included ≥1 binary outcome meta-analysis(es) pertaining to effectiveness with ≥1 clinical trial(s) published in NEJM, JAMA or Lancet. Effect sizes in trials from NEJM, JAMA or Lancet were compared with those from other trials in the same meta-analyses by deriving summary relative odds ratios (sRORs). Additional analyses examined separately early- and late-published trials in HIG journals and journal-specific effects. A total of 79 meta-analyses including 1043 clinical trials were analysed. Trials in HIG journals had similar effects to trials in other journals, when there was large-scale evidence, but showed more favourable results for experimental interventions when they were small. When HIG trials had less than 40 events, the sROR was 1.64 [95% confidence interval (95% CI): 1.23-2.18). The difference was most prominent when small early trials published in HIG journals were compared with subsequent trials [sROR 2.68 (95% CI: 1.33-5.38)]. Late-published HIG trials showed no consistent inflation of effects. The patterns did not differ beyond chance between NEJM, JAMA or Lancet. Small trials published in the most prestigious journals show more favourable effects for experimental interventions, and this is most prominent for early-published trials in such journals. No effect inflation is seen for large trials.

  20. Effects of general and alcohol-specific media literacy training on children's decision making about alcohol.

    Science.gov (United States)

    Austin, E W; Johnson, K K

    1997-01-01

    This article examines the immediate and delayed effects of media literacy training on third-grade children's perceptions of alcohol advertising, alcohol norms, expectancies for drinking, and behaviors toward alcohol. A Solomon four-group style experiment (N = 225) with two levels of the treatment factor assessed the effectiveness of in-school media literacy training for alcohol. The experiment compared a treatment that included the viewing of a videotape about television advertising along with the viewing of video clips of alcohol ads and discussion pertaining to alcohol advertising specifically versus one that included the viewing of the same general purpose media literacy videotape along with video clips of non-alcohol advertising and then discussion of advertising in general. The treatment had both immediate and delayed effects. Immediate effects included the children's increased understanding of persuasive intent, viewing of characters as less similar to people they knew in real life and less desirable, decreased desire to be like the characters, decreased expectation of positive consequences from drinking alcohol, and decreased likelihood to choose an alcohol-related product. Indirect effects also were found on their perceptions of television's realism and their views of social norms related to alcohol. Delayed effects were examined and confirmed on expectancies and behavior. The treatment was more effective when alcohol-specific, and it also was more effective among girls than boys.

  1. Decision-making in general practice: the effect of financial incentives on the use of laboratory analyses.

    Science.gov (United States)

    Munkerud, Siri Fauli

    2012-04-01

    This paper examines the reaction of general practitioners (GPs) to a reform in 2004 in the remuneration system for using laboratory services in general practice. The purpose of this paper is to study whether income motivation exists regarding the use of laboratory services in general practice, and if so, the degree of income motivation among general practitioners (GPs) in Norway. We argue that the degree of income motivation is stronger when the physicians are uncertain about the utility of the laboratory service in question. We have panel data from actual physician-patient encounters in general practices in the years 2001-2004 and use discrete choice analysis and random effects models. Estimation results show that an increase in the fees will lead to a small but significant increase in use. The reform led to minor changes in the use of laboratory analyses in GPs' offices, and we argue that financial incentives were diluted because they were in conflict with medical recommendations and existing medical practice. The patient's age has the most influence and the results support the hypothesis that the impact of income increases with increasing uncertainty about diagnosis and treatment. The policy implication of our results is that financial incentives alone are not an effective tool for influencing the use of laboratory services in GPs' offices.

  2. Testing concordance of instrumental variable effects in generalized linear models with application to Mendelian randomization

    Science.gov (United States)

    Dai, James Y.; Chan, Kwun Chuen Gary; Hsu, Li

    2014-01-01

    Instrumental variable regression is one way to overcome unmeasured confounding and estimate causal effect in observational studies. Built on structural mean models, there has been considerale work recently developed for consistent estimation of causal relative risk and causal odds ratio. Such models can sometimes suffer from identification issues for weak instruments. This hampered the applicability of Mendelian randomization analysis in genetic epidemiology. When there are multiple genetic variants available as instrumental variables, and causal effect is defined in a generalized linear model in the presence of unmeasured confounders, we propose to test concordance between instrumental variable effects on the intermediate exposure and instrumental variable effects on the disease outcome, as a means to test the causal effect. We show that a class of generalized least squares estimators provide valid and consistent tests of causality. For causal effect of a continuous exposure on a dichotomous outcome in logistic models, the proposed estimators are shown to be asymptotically conservative. When the disease outcome is rare, such estimators are consistent due to the log-linear approximation of the logistic function. Optimality of such estimators relative to the well-known two-stage least squares estimator and the double-logistic structural mean model is further discussed. PMID:24863158

  3. Short-term and long-term effects of diazepam on the memory for discrimination and generalization of scopolamine.

    Science.gov (United States)

    Casasola-Castro, C; Weissmann-Sánchez, L; Calixto-González, E; Aguayo-Del Castillo, A; Velázquez-Martínez, D N

    2017-10-01

    Benzodiazepines are among the most widely prescribed and misused psychopharmaceutical drugs. Although they are well-tolerated, they are also capable of producing amnestic effects similar to those observed after pharmacological or organic cholinergic dysfunction. To date, the effect of benzodiazepine diazepam on the memory for discrimination of anticholinergic drugs has not been reported. The aim of the present study was to analyze the immediate and long-term effects of diazepam on a drug discrimination task with scopolamine. Male Wistar rats were trained to discriminate between scopolamine and saline administration using a two-lever discrimination task. Once discrimination was acquired, the subjects were divided into three independent groups, (1) control, (2) diazepam, and (3) diazepam chronic administration (10 days). Subsequently, generalization curves for scopolamine were obtained. Additionally, the diazepam and control groups were revaluated after 90 days without having been given any other treatment. The results showed that diazepam produced a significant reduction in the generalization gradient for scopolamine, indicating an impairment of discrimination. The negative effect of diazepam persisted even 90 days after drug had been administered. Meanwhile, the previous administration of diazepam for 10 days totally abated the generalization curve and the general performance of the subjects. The results suggest that diazepam affects memory for the stimulus discrimination of anticholinergic drugs and does so persistently, which could be an important consideration during the treatment of amnesic patients with benzodiazepines.

  4. A simulation-based goodness-of-fit test for random effects in generalized linear mixed models

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus

    2006-01-01

    The goodness-of-fit of the distribution of random effects in a generalized linear mixed model is assessed using a conditional simulation of the random effects conditional on the observations. Provided that the specified joint model for random effects and observations is correct, the marginal...... distribution of the simulated random effects coincides with the assumed random effects distribution. In practice, the specified model depends on some unknown parameter which is replaced by an estimate. We obtain a correction for this by deriving the asymptotic distribution of the empirical distribution...

  5. A simulation-based goodness-of-fit test for random effects in generalized linear mixed models

    DEFF Research Database (Denmark)

    Waagepetersen, Rasmus Plenge

    The goodness-of-fit of the distribution of random effects in a generalized linear mixed model is assessed using a conditional simulation of the random effects conditional on the observations. Provided that the specified joint model for random effects and observations is correct, the marginal...... distribution of the simulated random effects coincides with the assumed random effects distribution. In practice the specified model depends on some unknown parameter which is replaced by an estimate. We obtain a correction for this by deriving the asymptotic distribution of the empirical distribution function...

  6. Effect of a tailored physical activity intervention delivered in general practice settings: results of a randomized controlled trial

    NARCIS (Netherlands)

    Sluijs, van E.M.F.; Poppel - Bruinvels, van M.N.M.; Twisk, J.W.R.; Paw, M.J.M. Chin A; Calfas, K.J.; Mechelen, van W.

    2005-01-01

    OBJECTIVES: We evaluated the effectiveness of a minimal intervention physical activity strategy (physician-based assessment and counseling for exercise [PACE]) applied in general practice settings in the Netherlands. METHODS: Randomization took place at the general practice level. Participants were

  7. Effect of a tailored physical activity intervention delivered in general practice settings: results of a randomized controlled trial

    NARCIS (Netherlands)

    van Sluijs, E.M.F.; van Poppel-Bruinvels, M.N.M.; Twisk, J.W.R.; Chin A Paw, M.J.M.; Calfas, K.J.; van Mechelen, W.

    2005-01-01

    Objectives. We evaluated the effectiveness of a minimal intervention physical activity strategy (physician-based assessment and counseling for exercise [PACE]) applied in general practice settings in the Netherlands. Methods. Randomization took place at the general practice level. Participants were

  8. EFFECTS OF DYNAMIC AND STATIC STRETCHING WITHIN GENERAL AND ACTIVITY SPECIFIC WARM-UP PROTOCOLS

    Directory of Open Access Journals (Sweden)

    Michael Samson

    2012-06-01

    Full Text Available The purpose of the study was to determine the effects of static and dynamic stretching protocols within general and activity specific warm-ups. Nine male and ten female subjects were tested under four warm-up conditions including a 1 general aerobic warm-up with static stretching, 2 general aerobic warm-up with dynamic stretching, 3 general and specific warm-up with static stretching and 4 general and specific warm-up with dynamic stretching. Following all conditions, subjects were tested for movement time (kicking movement of leg over 0.5 m distance, countermovement jump height, sit and reach flexibility and 6 repetitions of 20 metre sprints. Results indicated that when a sport specific warm-up was included, there was an 0.94% improvement (p = 0.0013 in 20 meter sprint time with both the dynamic and static stretch groups. No such difference in sprint performance between dynamic and static stretch groups existed in the absence of the sport specific warm-up. The static stretch condition increased sit and reach range of motion (ROM by 2.8% more (p = 0.0083 than the dynamic condition. These results would support the use of static stretching within an activity specific warm-up to ensure maximal ROM along with an enhancement in sprint performance

  9. Generalized Ford-Vilenkin approach for the dynamical Casimir effect

    International Nuclear Information System (INIS)

    Rego, Andreson L.C.; Alves, Danilo Teixeira; Alves, Joao Paulo da Silva

    2012-01-01

    Full text: In the 70s decade the first works investigating the quantum problem of the radiation emitted by moving mirrors in vacuum were published by Moore, DeWitt, Fulling and Davies. This effect, usually named dynamical Casimir effect (DCE). The DCE is also related to several other problems like particle creation in cosmological models and radiation emitted by collapsing black holes, decoherence, entanglement the Unruh effect. The DCE has been subject to experimental investigations: few months ago, Wilson and collaborators have announced the first experimental observation of the DCE. The theory of the DCE has been investigated by many authors, among them Ford and Vilenkin [L.H. Ford and A. Vilenkin, Phys. Rev. D 25, 2569 (1982)] who developed a perturbative method, which can be applied to moving mirrors in small displacements δq(t) = εF (t) and with nonrelativistic velocities. The usual application of the Ford-Vilenkin approach to the calculation of the spectrum of the created particles, results in the spectral distribution proportional to ε 2 . In the present paper, we consider a real massless scalar field and a moving mirror in a two-dimensional spacetime, satisfying Dirichlet boundary condition at the instantaneous position of the mirror, for large displacements and relativistic velocities. We generalize the Ford-Vilenkin approach to the calculation of the spectral density of the created particles, obtaining formulas for the spectrum up to order ε n . (author)

  10. Effect of a generalized particle momentum distribution on plasma nuclear fusion rates

    International Nuclear Information System (INIS)

    Kim, Yeong E.; Zubarev, Alexander L.

    2006-01-01

    We investigate the effect of a generalized particle momentum distribution derived by Galitskii and Yakimets (GY) on nuclear reaction rates in plasma. We derive an approximate semi-analytical formula for nuclear fusion reaction rate between nuclei in a plasma (quantum plasma nuclear fusion; or QPNF). The QPNF formula is applied to calculate deuteron-deuteron fusion rate in a plasma, and the results are compared with the results calculated with the conventional Maxwell-Boltzmann velocity distribution. As an application, we investigate the deuteron-deuteron fusion rate for mobile deuterons in a deuterated metal/alloy. The calculated deuteron-deuteron fusion rates at low energies are enormously enhanced due to the modified tail of the GY's generalized momentum distribution. Our preliminary estimates indicate also that the deuteron-lithium (D+Li) fusion rate and the proton-lithium (p+Li) fusion rate in a metal/alloy at ambient temperatures are also substantially enhanced. (author)

  11. EFFECT OF RECOMBINANT TISSUE-PLASMINOGEN ACTIVATOR ON INTRAABDOMINAL ABSCESS FORMATION IN RATS WITH GENERALIZED PERITONITIS

    NARCIS (Netherlands)

    van Goor, Harry; de Graaf, JS; Kooi, K; Sluiter, WJ; Bom, VJJ; van der Meer, J; Bleichrodt, RP

    1994-01-01

    BACKGROUND: During generalized peritonitis, intraabdominal fibrin deposition is stimulated whereas fibrinolytic activity is reduced, which predisposes intra-abdominal abscess formation. We investigated the effects of increasing the intra-abdominal fibrinolytic activity on abscess formation by

  12. Spatial variability in floodplain sedimentation: the use of generalized linear mixed-effects models

    Directory of Open Access Journals (Sweden)

    A. Cabezas

    2010-08-01

    Full Text Available Sediment, Total Organic Carbon (TOC and total nitrogen (TN accumulation during one overbank flood (1.15 y return interval were examined at one reach of the Middle Ebro River (NE Spain for elucidating spatial patterns. To achieve this goal, four areas with different geomorphological features and located within the study reach were examined by using artificial grass mats. Within each area, 1 m2 study plots consisting of three pseudo-replicates were placed in a semi-regular grid oriented perpendicular to the main channel. TOC, TN and Particle-Size composition of deposited sediments were examined and accumulation rates estimated. Generalized linear mixed-effects models were used to analyze sedimentation patterns in order to handle clustered sampling units, specific-site effects and spatial self-correlation between observations. Our results confirm the importance of channel-floodplain morphology and site micro-topography in explaining sediment, TOC and TN deposition patterns, although the importance of other factors as vegetation pattern should be included in further studies to explain small-scale variability. Generalized linear mixed-effect models provide a good framework to deal with the high spatial heterogeneity of this phenomenon at different spatial scales, and should be further investigated in order to explore its validity when examining the importance of factors such as flood magnitude or suspended sediment concentration.

  13. Effects of Marijuana on Ictal and Interictal EEG Activities in Idiopathic Generalized Epilepsy.

    Science.gov (United States)

    Sivakumar, Sanjeev; Zutshi, Deepti; Seraji-Bozorgzad, Navid; Shah, Aashit K

    2017-01-01

    Marijuana-based treatment for refractory epilepsy shows promise in surveys, case series, and clinical trials. However, literature on their EEG effects is sparse. Our objective is to analyze the effect of marijuana on EEG in a 24-year-old patient with idiopathic generalized epilepsy treated with cannabis. We blindly reviewed 3 long-term EEGs-a 24-hour study while only on antiepileptic drugs, a 72-hour EEG with Cannabis indica smoked on days 1 and 3 in addition to antiepileptic drugs, and a 48-hour EEG with combination C indica/sativa smoked on day 1 plus antiepileptic drugs. Generalized spike-wave discharges and diffuse paroxysmal fast activity were categorized as interictal and ictal, based on duration of less than 10 seconds or greater, respectively. Data from three studies concatenated into contiguous time series, with usage of marijuana modeled as time-dependent discrete variable while interictal and ictal events constituted dependent variables. Analysis of variance as initial test for significance followed by time series analysis using Generalized Autoregressive Conditional Heteroscedasticity model was performed. Statistical significance for lower interictal events (analysis of variance P = 0.001) was seen during C indica use, but not for C indica/sativa mixture (P = 0.629) or ictal events (P = 0.087). However, time series analysis revealed a significant inverse correlation between marijuana use, with interictal (P EEG data, we demonstrate a decrease in interictal and ictal electrographic events during marijuana use. Larger samples of patients and EEG, with standardized cannabinoid formulation and dosing, are needed to validate our findings.

  14. Effect of Epidural Block under General Anesthesia on Pulse Transit Time

    International Nuclear Information System (INIS)

    Choi, Byeong Cheol; Kim, Seong Min; Jung, Dong Keun; Kim, Gi Ryon; Lee, He Jeong; Jeon, Gye Rock

    2005-01-01

    Epidural block under general anesthesia has been widely used to control postoperative pain. In this anesthetic state many hemodynamic parameters are changed. Moreover pulse transit time is influenced by this memodynamic change. PPT change in the finger and the toe due to relaxation of arterial wall muscle after general anesthesia and epidural block under general anesthesia. This study, in the both general anesthesia and epidural block under general anesthesia, ΔPTT of the toe and of the finger are measured. In addition, ΔPTT(toe-finger) of the epidural block under general anesthesia and of the general anesthesia were compared

  15. General conclusions

    International Nuclear Information System (INIS)

    Tubiana, M.

    1993-01-01

    In conclusion, a general consensus of a number of points which the author endeavours to summarize in this article: -doctors are an excellent channel for passing on information to the public -doctors feel that they do not know enough about the subject and a training on radiobiology and radiation protection is a necessity for them -communication between doctors and the general public is poor in this field -research should be encouraged in numerous areas such as: carcinogenic effect of low doses of radiation, pedagogy and risk perception

  16. Effect of Guided Collaboration on General and Special Educators' Perceptions of Collaboration and Student Achievement

    Science.gov (United States)

    Laine, Sandra

    2013-01-01

    This study investigated the effects of a guided collaboration approach during professional learning community meetings (PLC's) on the perceptions of general and special educators as well as the effect on student performance as measured by benchmark evaluation. A mixed methodology approach was used to collect data through surveys, weekly…

  17. Effective medium super-cell approximation for interacting disordered systems: an alternative real-space derivation of generalized dynamical cluster approximation

    International Nuclear Information System (INIS)

    Moradian, Rostam

    2006-01-01

    We develop a generalized real-space effective medium super-cell approximation (EMSCA) method to treat the electronic states of interacting disordered systems. This method is general and allows randomness both in the on-site energies and in the hopping integrals. For a non-interacting disordered system, in the special case of randomness in the on-site energies, this method is equivalent to the non-local coherent potential approximation (NLCPA) derived previously. Also, for an interacting system the EMSCA method leads to the real-space derivation of the generalized dynamical cluster approximation (DCA) for a general lattice structure. We found that the original DCA and the NLCPA are two simple cases of this technique, so the EMSCA is equivalent to the generalized DCA where there is included interaction and randomness in the on-site energies and in the hopping integrals. All of the equations of this formalism are derived by using the effective medium theory in real space

  18. ALERT. Adverse late effects of cancer treatment. Vol. 1. General concepts and specific precepts

    Energy Technology Data Exchange (ETDEWEB)

    Rubin, Philip; Constine, Louis S. [Univ. Rochester Medical Center, NY (United States). Dept. of Radiation Oncology; Marks, Lawrence B. (ed.) [Univ. North Carolina and Lineberger, Comprehensive Cancer Center, Chapel Hill, NC (United States). Dept. of Radiation Oncology

    2014-09-01

    Considers in detail the general concepts and principles relevant to the adverse late effects of cancer treatment. Explains the molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Includes chapters on legal issues, economic aspects, nursing, psychological issues and quality of life. The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT - Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.

  19. ALERT. Adverse late effects of cancer treatment. Vol. 1. General concepts and specific precepts

    International Nuclear Information System (INIS)

    Rubin, Philip; Constine, Louis S.; Marks, Lawrence B.

    2014-01-01

    Considers in detail the general concepts and principles relevant to the adverse late effects of cancer treatment. Explains the molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Includes chapters on legal issues, economic aspects, nursing, psychological issues and quality of life. The literature on the late effects of cancer treatment is widely scattered in different journals since all major organ systems are affected and management is based on a variety of medical and surgical treatments. The aim of ALERT - Adverse Late Effects of Cancer Treatment is to offer a coherent multidisciplinary approach to the care of cancer survivors. The central paradigm is that cytotoxic multimodal therapy results in a perpetual cascade of events that affects each major organ system differently and is expressed continually over time. Essentially, radiation and chemotherapy are intense biologic modifiers that allow for cancer cure and cancer survivorship but accelerate senescence of normal tissues and increase the incidence of age-related diseases and second malignant tumors. Volume 1 of this two-volume work focuses on the general concepts and principles relevant to late effects and on the dynamic interplay of molecular, cytologic and histopathologic events that lead to altered physiologic and metabolic functions and their clinical manifestations. Chapters are also included on legal issues, economic aspects, nursing, psychological issues and quality of life.

  20. Effects of conventional and problem-based learning on clinical and general competencies and career development

    NARCIS (Netherlands)

    Cohen-Schotanus, Janke; Muijtjens, Arno M. M.; Schonrock-Adema, Johanna; Geertsma, Jelle; van der Vleuten, Cees P. M.

    OBJECTIVE: To test hypotheses regarding the longitudinal effects of problem-based learning (PBL) and conventional learning relating to students' appreciation of the curriculum, self-assessment of general competencies, summative assessment of clinical competence and indicators of career development.

  1. Effects of music therapy under general anesthesia in patients undergoing abdominal surgery.

    Science.gov (United States)

    Kahloul, Mohamed; Mhamdi, Salah; Nakhli, Mohamed Said; Sfeyhi, Ahmed Nadhir; Azzaza, Mohamed; Chaouch, Ajmi; Naija, Walid

    2017-12-01

    Music therapy, an innovative approach that has proven effectiveness in many medical conditions, seems beneficial also in managing surgical patients. The aim of this study is to evaluate its effects, under general anesthesia, on perioperative patient satisfaction, stress, pain, and awareness. This is a prospective, randomized, double-blind study conducted in the operating theatre of visceral surgery at Sahloul Teaching Hospital over a period of 4 months. Patients aged more than 18 undergoing a scheduled surgery under general anesthesia were included. Patients undergoing urgent surgery or presenting hearing or cognitive disorders were excluded. Before induction, patients wore headphones linked to an MP3 player. They were randomly allocated into 2 groups: Group M (with music during surgery) and group C (without music). Hemodynamic parameters, quality of arousal, pain experienced, patient's satisfaction, and awareness incidence during anesthesia were recorded. One hundred and forty patients were included and allocated into 2 groups that were comparable in demographic characteristics, surgical intervention type and anesthesia duration. Comparison of these two groups regarding the hemodynamic profile found more stability in group M for systolic arterial blood pressure. A calm recovery was more often noted in group M (77.1% versus 44%, p Music therapy is a non-pharmacological, inexpensive, and non-invasive technique that can significantly enhance patient satisfaction and decrease patients' embarrassing experiences related to perioperative stress, pain, and awareness.

  2. Polyphenol-rich food general and on pregnancy effects: a review.

    Science.gov (United States)

    Hahn, Marla; Baierle, Marília; Charão, Mariele F; Bubols, Guilherme B; Gravina, Fernanda S; Zielinsky, Paulo; Arbo, Marcelo D; Cristina Garcia, Solange

    2017-07-01

    This review aimed to investigate possible protective or deleterious effects of polyphenol-rich foods (PRF) on chronic diseases, e.g. cardiovascular, and in pregnant women, along with their antioxidant and anti-inflammatory action. A great variety of foods and beverages, such as herbal teas, grape and orange derivatives, dark chocolate, and many others contain high concentrations of flavonoids and are freely consumed by the general population. In humans, PRF consumption reduces lipid peroxidation, and several studies have shown a positive correlation between an increased consumption of PRF and a decrease in the incidence of cardiovascular disease. On the other hand, current studies have suggested that maternal ingestion of PRF, especially during the third trimester of pregnancy, could be associated to fetal ductal constriction (DC). Fetuses exposed to this type of diet show higher ductal velocities and lower pulsatility indexes, as well as larger right ventricles than those exposed to minimal amounts of these substances. The underlying mechanism involved in these conditions has not been entirely elucidated, but it seems to be a result of the antioxidant and anti-inflammatory effects of polyphenols by some pathway. Furthermore, taking into account the deleterious effect in late-pregnancy against the numerous positive effects associated to polyphenols, this dual behavior deserves attention particularly to control the dietary ingestion of PRF during gestation. In this line, same PRF, natural constituents of human diet, may represent risk to fetal in late pregnancy compared to the use of nonsteroidal anti-inflammatory drugs.

  3. Effect of resilient liner on masticatory efficiency and general patient satisfaction in completely edentulous patients

    DEFF Research Database (Denmark)

    Mangtani, Nidhi; Pillai, Rajath; Babu, Dinesh

    2015-01-01

    Objectives: To assess the effect of resilient lined denture on patient masticatory efficiency, general patient satisfaction and denture quality as compare to conventional complete denture over a period of one year. Material and methodology: A total of 28 completely edentulous patients (14 males...... denture liner – group 2). All patients were clinically evaluated to assess the denture quality, and administered questionnaires for masticatory efficiency and patients general satisfaction level at three intervals i.e. one month (T0), 6 months (T1) and 1 year post-insertion (T2). Results: Statistical...... masticatory efficiency improved significantly over time in controls, while in experimental group masticatory efficiency remained the same (p>.05) for almost all the questions. Patient general satisfaction score at different time intervals for each question showed no significant difference (P>.05) on inter...

  4. Parental Divorce and Generalized Trust

    OpenAIRE

    Viitanen, Tarja

    2011-01-01

    This paper examines the effect of parental divorce during childhood on generalized trust later on in life using Australian HILDA panel data. The dependent variable is composed of answers to the statement: “Generally speaking, most people can be trusted”. The main explanatory variables include the occurrence of parental divorce for the whole sample and the age at which parents divorced for the sub-sample. The analysis is conducted using random effects ordered probit, correlated random effects ...

  5. GENERAL SURGERY

    African Journals Online (AJOL)

    effect of fatigue on patient safety, and owing to increasing emphasis on lifestyle issues .... increasing emphasis on an appropriate work-life balance in professional life.10 ... experience, were the most negative about the EWTD in general.3,13 ...

  6. The effectiveness of isometric exercises as compared to general exercises in the management of chronic non-specific neck pain.

    Science.gov (United States)

    Khan, Muhammad; Soomro, Rabail Rani; Ali, Syed Shahzad

    2014-09-01

    To evaluate the effectiveness of isometric exercises as compared to general exercises in chronic non-specific neck pain. For this randomised controlled trial total 68 patients (34 each group) with chronic non-specific neck pain were recruited from Alain Poly Clinic and Institute of Physical Medicine & Rehabilitation Dow University of Health Sciences, Karachi between May, 2012 and August, 2012. Simple randomisation method was used to assign participants into isometric exercise group and general exercise groups. The isometric exercise group performed exercises for neck muscle groups with a rubber band and general exercises group performed active range of movement exercises for all neck movements. Patients in both groups received 3 supervised treatment sessions per week for 12 weeks. Visual Analogue Scale (VAS), North wick Park Neck Pain Questionnaire and goniometer were used to assess pain, disability and neck range of movements at baseline and after 12 weeks. Both interventions showed statistically significant improvements in pain, function and range of movement p = 0.001f or isometric exercise group, p = 0.04 for general exercises group and p = 0.001 for range of movement. However, mean improvements in post intervention VAS score and North wick Park Neck Pain Questionnaire score was better in isometric exercises group as compared to general exercise group. In conclusion, both interventions are effective in the treatment of chronic non-specific neck pain however; isometric exercises are clinically more effective than general exercises.

  7. A Generalized Least Squares Regression Approach for Computing Effect Sizes in Single-Case Research: Application Examples

    Science.gov (United States)

    Maggin, Daniel M.; Swaminathan, Hariharan; Rogers, Helen J.; O'Keeffe, Breda V.; Sugai, George; Horner, Robert H.

    2011-01-01

    A new method for deriving effect sizes from single-case designs is proposed. The strategy is applicable to small-sample time-series data with autoregressive errors. The method uses Generalized Least Squares (GLS) to model the autocorrelation of the data and estimate regression parameters to produce an effect size that represents the magnitude of…

  8. The generalized Abel-Plana formula with applications to Bessel functions and casimir effect

    International Nuclear Information System (INIS)

    Saharian, Aram A.

    2007-08-01

    One of the most efficient methods for the evaluation of the vacuum expectation values for physical observables in the Casimir effect is based on using the Abel-Plana summation formula. This enables to derive the renormalized quantities in a manifestly cutoff independent way and to present them in the form of strongly convergent integrals. However, applications of the Abel- Plana formula, in its usual form, are restricted by simple geometries when the eigenmodes have a simple dependence on quantum numbers. The author generalized the Abel-Plana formula which essentially enlarges its application range. Based on this generalization, formulae have been obtained for various types of series over the zeros of combinations of Bessel functions and for integrals involving these functions. It has been shown that these results generalize the special cases existing in literature. Further, the derived summation formulae have been used to summarize series arising in the direct mode summation approach to the Casimir effect for spherically and cylindrically symmetric boundaries, for boundaries moving with uniform proper acceleration, and in various braneworld scenarios. This allows to extract from the vacuum expectation values of local physical observables the parts corresponding to the geometry without boundaries and to present the boundary-induced parts in terms of integrals strongly convergent for the points away from the boundaries. As a result, the renormalization procedure for these observables is reduced to the corresponding procedure for bulks without boundaries. The present paper reviews these results. We also aim to collect the results on vacuum expectation values for local physical observables such as the field square and the energy-momentum tensor in manifolds with boundaries for various bulk and boundary geometries. (author)

  9. On the stability analysis of a general discrete-time population model involving predation and Allee effects

    International Nuclear Information System (INIS)

    Merdan, H.; Duman, O.

    2009-01-01

    This paper presents the stability analysis of equilibrium points of a general discrete-time population dynamics involving predation with and without Allee effects which occur at low population density. The mathematical analysis and numerical simulations show that the Allee effect has a stabilizing role on the local stability of the positive equilibrium points of this model.

  10. Generalized Models from Beta(p, 2) Densities with Strong Allee Effect: Dynamical Approach

    OpenAIRE

    Aleixo, Sandra M.; Rocha, J. Leonel

    2012-01-01

    A dynamical approach to study the behaviour of generalized populational growth models from Beta(p, 2) densities, with strong Allee effect, is presented. The dynamical analysis of the respective unimodal maps is performed using symbolic dynamics techniques. The complexity of the correspondent discrete dynamical systems is measured in terms of topological entropy. Different populational dynamics regimes are obtained when the intrinsic growth rates are modified: extinction, bistability, chaotic ...

  11. Effects of a team-based assessment and intervention on patient safety culture in general practice

    DEFF Research Database (Denmark)

    Hoffmann, B; Müller, V; Rochon, J

    2014-01-01

    Background: The measurement of safety culture in healthcare is generally regarded as a first step towards improvement. Based on a self-assessment of safety culture, the Frankfurt Patient Safety Matrix (FraTrix) aims to enable healthcare teams to improve safety culture in their organisations....... In this study we assessed the effects of FraTrix on safety culture in general practice. Methods: We conducted an open randomised controlled trial in 60 general practices. FraTrix was applied over a period of 9 months during three facilitated team sessions in intervention practices. At baseline and after 12...... months, scores were allocated for safety culture as expressed in practice structure and processes (indicators), in safety climate and in patient safety incident reporting. The primary outcome was the indicator error management. Results: During the team sessions, practice teams reflected on their safety...

  12. General Surveillance of the soil ecosystem: An approach to monitoring unexpected adverse effects of GMO's

    NARCIS (Netherlands)

    Smit, E.; Bakker, P.A.H.M.; Bergmans, H.; Bloem, J.; Griffiths, B.; Rutgers, M.

    2012-01-01

    The commercial cultivation of genetically modified (GM) crops in the European Union (EU) necessitates, according to EU legislation, the setting up of a General Surveillance (GS) system that should be able to detect unanticipated effects of GM crops on the environment. Although the applicant is

  13. Zinc Addition Effects on General Corrosion of Austenitic Stainless Steels in PWR Primary Conditions

    International Nuclear Information System (INIS)

    Qiao Peipeng; Zhang Lefu; Liu Ruiqin; Jiang Suqing; Zhu Fawen

    2010-01-01

    Zinc addition effects on general corrosion of austenitic stainless steel 316 and 304 were investigated in simulated PWR primary coolant without zinc or with 50 ppb zinc addition at 315 degree C for 500 h. The results show that with the addition of zinc, the corrosion rate of austenitic stainless steel is effectively reduced, the surface oxide film is thinner, the morphology and chemical composition of surface oxide scales are evidently different from those without zinc. There are needle-like corrosion products on the surface of stainless steel 304. (authors)

  14. Effective and Robust Generalized Predictive Speed Control of Induction Motor

    Directory of Open Access Journals (Sweden)

    Patxi Alkorta

    2013-01-01

    Full Text Available This paper presents and validates a new proposal for effective speed vector control of induction motors based on linear Generalized Predictive Control (GPC law. The presented GPC-PI cascade configuration simplifies the design with regard to GPC-GPC cascade configuration, maintaining the advantages of the predictive control algorithm. The robust stability of the closed loop system is demonstrated by the poles placement method for several typical cases of uncertainties in induction motors. The controller has been tested using several simulations and experiments and has been compared with Proportional Integral Derivative (PID and Sliding Mode (SM control schemes, obtaining outstanding results in speed tracking even in the presence of parameter uncertainties, unknown load disturbance, and measurement noise in the loop signals, suggesting its use in industrial applications.

  15. Experiments to Distribute Map Generalization Processes

    Science.gov (United States)

    Berli, Justin; Touya, Guillaume; Lokhat, Imran; Regnauld, Nicolas

    2018-05-01

    Automatic map generalization requires the use of computationally intensive processes often unable to deal with large datasets. Distributing the generalization process is the only way to make them scalable and usable in practice. But map generalization is a highly contextual process, and the surroundings of a generalized map feature needs to be known to generalize the feature, which is a problem as distribution might partition the dataset and parallelize the processing of each part. This paper proposes experiments to evaluate the past propositions to distribute map generalization, and to identify the main remaining issues. The past propositions to distribute map generalization are first discussed, and then the experiment hypotheses and apparatus are described. The experiments confirmed that regular partitioning was the quickest strategy, but also the less effective in taking context into account. The geographical partitioning, though less effective for now, is quite promising regarding the quality of the results as it better integrates the geographical context.

  16. Effects of therapist general self-disclosure and countertransference disclosure on ratings of the therapist and session.

    Science.gov (United States)

    Myers, David; Hayes, Jeffrey A

    2006-01-01

    Therapist decisions about self-disclosure depend theoretically upon both content and context, such as the quality of the therapeutic relationship. In this analogue study, 224 undergraduates viewed 1 of 3 videos for which the working alliance was described as positive or negative and in which a therapist made general self-disclosures, countertransference disclosures, or no disclosures. Interaction effects indicated that participants rated sessions as deeper and the therapist as more expert when the therapist made general disclosures compared to no disclosures, but only when the alliance was positive. When the alliance was negative, participants perceived sessions as shallower and the therapist as less expert when the therapist made either general or countertransference disclosures compared to no disclosures. (PsycINFO Database Record (c) 2010 APA, all rights reserved).

  17. Effects of combined general anesthesia and thoracic epidural ...

    African Journals Online (AJOL)

    2015-11-02

    Nov 2, 2015 ... Key words: Bupivacaine, combined-general-epidural anesthesia, inflammatory cytokines, laparoscopic cholecystectomy, ..... spinal-epidural anaesthesia for caesarean section. Left lateral ... laparoscopic segmental colectomy.

  18. [General principles of effective communication between physician and patient with selected mental disorders].

    Science.gov (United States)

    Błaszczyk, Justyna; Bobińska, Kinga; Filip, Maria; Gałecki, Piotr

    2015-04-01

    Faced with the growing frequency of mental disorders occurrence and considering the necessity of improving the patient care, it is particularly important that physicians of different specialties knew the general principles of effective communication with patients who are mentally ill. Equally important is to spread the knowledge of the symptomatology of various mental illnesses. Studies published by the Institute of Psychiatry and Neurology involving persons between 18 and 64 years old, show that 8 millions Poles suffers or suffered from mental disorders. This represents almost 25% of Polish society. The above data confirm, that basic knowledge of criteria for diagnosing mental disorders and their treatment by primary care physicians, determines the success of the entire health care system. It must be taken into consideration that frequently patients seeing general practitioner (GP) are suffering from more than one mental illness or it is accompanied by somatic disease. Adequate communication determines effective treatment. Simple yet exact message, ability to adapt it to patient and problems reported by him, is a valuable means in daily medical practice. It reduces the risk of iatrogenic disorder, encourages the efficiency of the entire therapeutic process. Good cooperation with the patient is also determined by patience, empathy, understanding, and competence. The aim of this study is to present the principles of effective communication between doctor and patient suffering from selected mental disorders. The article defines the concept of communication. It shows symptomatology of primary psychiatric disorders. Moreover, the most common difficulties in relationship between the doctor and the patient had been pointed. © 2015 MEDPRESS.

  19. Effect of personal and work stress on burnout, job satisfaction and general health of hospital nurses in South Africa

    Directory of Open Access Journals (Sweden)

    Natasha Khamisa

    2017-10-01

    Full Text Available The majority of studies to date have focused on the effects of work stress in the nursing environment, with the effect of personal stress in nursing being less explored. This study sought to determine whether personal stress is a more significant predictor of burnout, job satisfaction and general health than work stress. Of the 1200 nurses randomly selected to participate in the study, 895 agreed to complete six questionnaires over 3 weeks. Data was analysed using hierarchical multiple linear regression. Findings revealed that personal stress is a better predictor of burnout and general health than job satisfaction, which is better predicted by work stress. The findings of this study could inform potential solutions to reduce the impact of personal and work stress on burnout, job satisfaction and general health. Coping strategies and staffing strategies need to be evaluated within developing contexts such as South Africa to as certain their effectiveness.

  20. GINGER (Gyroscopes IN General Relativity), a ring lasers array to measure the Lense-Thirring effect

    Science.gov (United States)

    Di Virgilio, Angela D. V.

    The purpose of the GINGER is to perform the first test of general relativity (not considering the gravitational redshift measurements) in a terrestrial laboratory, using light as a probe. The experiment will complement the ones in space, performed or under way, with an entirely different technique and at a far lower cost. The methodology is based on ring-lasers, which are extremely accurate rotation sensors and can not only sense purely kinematical rotations (Sagnac effect accounting for the Earth rotation, polar motion of the terrestrial axis, local rotational movements of the laboratory due to the Earth crust dynamics...), but also general relativistic contributions such as the de Sitter effect (coupling between the gravito-electric field of the earth and the kinematical rotation) and the Lense-Thirring effect (inertial frame dragging due to the angular momentum of the earth). In order to reveal the latter effects, ring-laser response must be improved to be able to measure the effective rotation vector (kinematic plus GR terms) with an accuracy of 1 part in 109 or better. This is a challenging technological aspect, which however has been accurately taken into account by designing a system of ring lasers that will be implemented in this project. A ring laser have been installed inside the underground laboratory of GranSasso, with the purpose to see if an underground location is the right choice for GINGER. The apparatus and the preliminary results will be discussed.

  1. The Effect of General Creative Personality and Freedom of Task Choice on Adolescents' Social Creativity

    Science.gov (United States)

    Gu, Chuanhua; Hu, Bi Ying; Ngwira, Flemmings Fishani; Jing, Zhi; Zhou, Zongkui

    2016-01-01

    This study investigated the effect of general creative personality and freedom of task choice on the social creativity of adolescents. The results indicated, first, that senior high school students scored higher than junior high school students. Second, girls scored higher than boys on originality, fluency, flexibility, appropriateness, and…

  2. Effect of electromagnetic radiations from mobile phone base stations on general health and salivary function.

    Science.gov (United States)

    Singh, Kushpal; Nagaraj, Anup; Yousuf, Asif; Ganta, Shravani; Pareek, Sonia; Vishnani, Preeti

    2016-01-01

    Cell phones use electromagnetic, nonionizing radiations in the microwave range, which some believe may be harmful to human health. The present study aimed to determine the effect of electromagnetic radiations (EMRs) on unstimulated/stimulated salivary flow rate and other health-related problems between the general populations residing in proximity to and far away from mobile phone base stations. A total of four mobile base stations were randomly selected from four zones of Jaipur, Rajasthan, India. Twenty individuals who were residing in proximity to the selected mobile phone towers were taken as the case group and the other 20 individuals (control group) who were living nearly 1 km away in the periphery were selected for salivary analysis. Questions related to sleep disturbances were measured using Pittsburgh Sleep Quality Index (PSQI) and other health problems were included in the questionnaire. Chi-square test was used for statistical analysis. It was unveiled that a majority of the subjects who were residing near the mobile base station complained of sleep disturbances, headache, dizziness, irritability, concentration difficulties, and hypertension. A majority of the study subjects had significantly lesser stimulated salivary secretion (P base stations on the health and well-being of the general population cannot be ruled out. Further studies are warranted to evaluate the effect of electromagnetic fields (EMFs) on general health and more specifically on oral health.

  3. Effect of Oral Midazolam Premedication on Children's Co-operation Before General Anesthesia in Pediatric Dentistry.

    Science.gov (United States)

    Kaviani, Nasser; Shahtusi, Mina; Haj Norousali Tehrani, Maryam; Nazari, Sara

    2014-09-01

    Premedication is expedient in reducing the psychological trauma from recalling the unpleasant pre-anesthetic phases, hence, inducing a trouble-free anesthesia. This study aimed to determine the effectiveness of oral midazolam in co-operation of the subjects before general anesthesia and in recalling the pre-anesthetic phases, performed on children candidate for dental treatment under general anesthesia. In this prospective clinical trial study, 62 healthy non-cooperative children, candidate for dental treatment under general anesthesia, were randomly divided into study and control groups. The children received 20ml orange juice, 20 minutes before starting the anesthesia. The juice of the test group contained 0.5mg/kg of midazolam and that of the control group included no medication. The induction and the maintenance process of anesthesia were similar in both groups. The manner of subjects when separated from parents, their cooperation during intravenous catheterization, and recalling the pre-anesthetic events were recorded. Data were analyzed by adopting chi-square and Mann-Whitney tests. Most of the children in the test group had a comfortable separation from parents, restful IV catheterization and 90% of the subjects did not recall the pre-anesthetic events. Under the circumstances of this study, it could be concluded that 0.5mg/kg oral midazolam premedication is effective for comfortable separation of children from parents and restful IV catheterization and also forgetting the pre-anesthetic events.

  4. Handwriting Without Tears(®): General Education Effectiveness Through a Consultative Approach.

    Science.gov (United States)

    Donica, Denise K

    2015-01-01

    This study explores the effectiveness of the Handwriting Without Tears(®) (HWT) kindergarten printing curriculum in general education through a consultative approach with occupational therapy. One cohort of students was the control (n = 19), whereas two other cohorts were experimental groups learning printing through the HWT curriculum (n = 20 each). The Test of Handwriting Skills-Revised (THS-R) was used to collect end-of-year legibility scores for all cohorts. Both experimental groups individually and both experimental groups combined into one group outperformed the control group on all 10 of the THS-R subtests-scoring significantly higher (p handwriting curriculum implementation and the success of HWT for printing instruction. Copyright © 2015 by the American Occupational Therapy Association, Inc.

  5. The Social Effects of Advertising as Perceived by Advertising Executives, Businessmen, and the General Public.

    Science.gov (United States)

    Surlin, Stuart H.

    This study attempts to compare the perceptions and self-reported behavior of high, middle, and low authoritarian advertising executives, business executives, and members of the general public concerning the social effects of advertising. For the advertising sample, a total of 393 men and women were selected according to their executive positions…

  6. The generalized second law of thermodynamics in generalized gravity theories

    International Nuclear Information System (INIS)

    Wu Shaofeng; Yang Guohong; Wang Bin; Zhang Pengming

    2008-01-01

    We investigate the generalized second law of thermodynamics (GSL) in generalized theories of gravity. We examine the total entropy evolution with time including the horizon entropy, the non-equilibrium entropy production, and the entropy of all matter, field and energy components. We derive a universal condition to protect the generalized second law and study its validity in different gravity theories. In Einstein gravity (even in the phantom-dominated universe with a Schwarzschild black hole), Lovelock gravity and braneworld gravity, we show that the condition to keep the GSL can always be satisfied. In f(R) gravity and scalar-tensor gravity, the condition to protect the GSL can also hold because the temperature should be positive, gravity is always attractive and the effective Newton constant should be an approximate constant satisfying the experimental bounds

  7. Higher-derivative terms in one-loop effective action for general trajectories of D-particles in Matrix theory

    International Nuclear Information System (INIS)

    Okawa, Yuji

    1999-01-01

    The one-loop effective action for general trajectories of D-particles in Matrix theory is calculated in the expansion with respect to the number of derivatives up to six, which gives the equation of motion consistently. The result shows that the terms with six derivatives vanish for straight-line trajectories, however, they do not vanish in general. This provides a concrete example that non-renormalization of twelve-fermion terms does not necessarily imply that of six-derivative terms

  8. Can tDCS enhance item-specific effects and generalization after linguistically motivated aphasia therapy for verbs?

    NARCIS (Netherlands)

    de Aguiar, Vania; Bastiaanse, Roelien; Capasso, Rita; Gandolfi, Marialuisa; Smania, Nicola; Rossi, Giorgio; Miceli, Gabriele

    2015-01-01

    Background: Aphasia therapy focusing on abstract properties of language promotes both item-specific effects and generalization to untreated materials. Neuromodulation with transcranial Direct Current Stimulation (tDCS) has been shown to enhance item-specific improvement, but its potential to enhance

  9. General practitioners' beliefs about effectiveness and intentions to prescribe smoking cessation medications: qualitative and quantitative studies

    Directory of Open Access Journals (Sweden)

    Marteau Theresa M

    2006-11-01

    Full Text Available Abstract Background General practitioners' (GPs negative beliefs about nicotine dependence medications may act as barriers to prescribing them. Methods Study1: Twenty-five GPs from 16 practices across London were interviewed in this qualitative study. Framework analysis was used to identify key themes. Study 2: A convenience sample of 367 GPs completed an internet-based survey. Path-analysis was used to examine the relations between beliefs and intentions to prescribe smoking cessation medications. Results Study 1: Whilst nicotine replacement therapy (NRT and bupropion were generally perceived as effective and cost-effective, the effectiveness of NRT was seen as critically dependent on behavioural support for smoking cessation. This dependence appeared to be influenced by perceptions that without support smokers would neglect psychological aspects of smoking and use NRT incorrectly. GPs perceived bupropion as dangerous and were concerned about its side-effects. Study 2: GPs' beliefs had medium (NRT, f2 = .23 to large (bupropion, f2=.45; NRT without support, f2=.59 effects on their intentions to prescribe medications. Beliefs about effectiveness of NRT and bupropion and the perceived danger of bupropion were the key predictors of intentions to prescribe NRT and bupropion, respectively. Beliefs about neglecting psychological aspects of smoking and incorrect use had indirect effects on intentions to prescribe NRT without support, operating via beliefs about effectiveness. Conclusion GPs vary in their beliefs about the effectiveness and safety of smoking cessation medications. Their intentions to prescribe these medications vary in line with these beliefs. Interventions aimed at increasing the likelihood with which GPs prescribe these medications may be more effective if they addressed these beliefs.

  10. Effectiveness of Positive Group Psychotherapy on Resiliency, Happiness and General Health on Women with a Substance Dependence Spouses

    Directory of Open Access Journals (Sweden)

    F sohrabi

    2016-03-01

    Full Text Available The aim of this study was to evaluate the effectiveness of positive group psychotherapy on resiliency, happiness and general health in Women with substance dependent spouse. The research design was quasi - experimental with pre-test, post-test and one-month follow - up with the control group. The sample was comprised of women whom their spouse were referred to addiction clinic. Twenty - four women were selected and randomly assigned to experimental and control groups. Both groups were assessed by Davidson Resilience Scale, Peterson happiness directions questionnaires and General Health Questionnaire (GHQ. Positive group psychotherapy was conducted on the experimental group for 14 sessions, each session lasting 90- minutes. The data was analyzed with ANCOVA. The findings indicated that the mean scores of post-test in the experimental groups on resilience, happiness, and public health, was significantly higher than the mean scores of post-test in control group. Benferroni test was indicating the stable effect of therapy. According to the findings, it can be said that group positive psychotherapy was effective in promoting resiliency, happiness, and general health of women with the dependent drug spouses.

  11. The effects of echolalia on acquisition and generalization of receptive labeling in autistic children.

    OpenAIRE

    Charlop, M H

    1983-01-01

    This investigation, consisting of two experiments, was designed to assess the effects of autistic immediate echolalia on acquisition and generalization of receptive labeling tasks. Experiment 1 addressed whether autistic children could use their echolalia to facilitate acquisition. The results indicated that incorporating echolalia (echo of the requested object's label) into the task before manual response (handing the requested object to the experimenter) facilitated receptive labeling. Expe...

  12. Pre-exposure and retrieval effects on generalization of contextual fear

    NARCIS (Netherlands)

    Sevenster, D.; de Oliveira Alvares, L.; D'Hooge, R.

    2018-01-01

    The degree of generalization from a fearful context to other contexts is determined by precision of the original fear memory. Experiences before and after fear learning affect memory precision. Pre-exposure to a similar context before context conditioning results in increased generalization to the

  13. The Effect of Electromagnetic Waves on the General Health of Zahedan Gas Power Plant Personnel

    Directory of Open Access Journals (Sweden)

    Fereydoon Laal

    2016-08-01

    Full Text Available Abstract Introduction: With ever improving technology and increasing the use of high voltage power in industrial environments, concerns about the destructive effects of electromagnetic waves on human health have increased. Thus the present study aims to evaluate the effects of electromagnetic waves on the general health of Zahedan gas power plant personnel. Materials & Method: The present case-control study investigated the health of people at one point of time and their amount of exposure to electromagnetic waves at the same time. The data collection tool in this study was 28-item general health questionnaire (GHQ-28. After measuring the electromagnetic waves at distances of 1, 1.5 and 3 meters at high voltage power substations and data extraction, the data were entered to SPSS software and analyzed by descriptive statistics, t-test and chi-square. Results: In this study, the age and experience variables were not significantly different in two groups (p> 0.05. The highest magnetic fields in high voltage power substations was at a distance of 1 meter in the substation 607 (28/1 mG and in precision tool work units (7.03 mG. The results showed that the depressive and general health symptoms were significantly different between the exposed and unexposed groups (p = 0.04, however the difference was not significant in terms of physical performance, anxiety and social performance (p> 0.05. Conclusion: although the level of exposure was lower than standard level determined in Iran, the significant difference of the general health and depression between the two groups, explains the necessity of conducting more studies in this regard. Also by reducing the exposure time and increasing people’s awareness it is possible to take important steps to reduce exposure and complications.

  14. Generally representative is generally representative: comment on Shuttleworth-Edwards.

    Science.gov (United States)

    Taylor, Nicola

    2016-10-01

    The aim of this paper is to provide comment on Shuttleworth-Edwards' criticism of the general population norms created for the South African adaptation of the WAIS-IV. In her criticism, she states that the norms are not applicable for any groups in South Africa, based on the fact that the norms were not stratified according to quality of education. A discussion of some of the key issues that impact on the creation of general population norms in the South African context is provided. Demographic characteristics such as education level, quality of education, urban and rural demarcations, and home language are all considered. While the utility of within-group norms is not denied, the adoption of these without reference to the general population is not advised. To recommend that practitioners simply dispense with the general population norm without evidence that it creates misclassification or does not function effectively for the intended population lacks scientific merit at the current time. The need for clinical studies and further predictive validity research using the South African adaptation of the WAIS-IV is crucial to demonstrate the continued utility of the test in the South African context. Additional reference groups will improve the amount of comparative information available for clinicians to be able to make better informed decisions for diagnosis, but the general population norms will be an important starting point in this process.

  15. The generalized Q-S synchronization between the generalized Lorenz canonical form and the Roessler system

    International Nuclear Information System (INIS)

    Yang Yunqing; Chen Yong

    2009-01-01

    In this paper, we investigate the generalized Q-S synchronization between the generalized Lorenz canonical form and the Roessler system. Firstly, we transform an arbitrary generalized Lorenz system to the generalized Lorenz canonical form, and the relation between the parameter of the generalized Lorenz system and the parameter of the generalized Lorenz canonical form are shown. Secondly, we extend the scheme present by [Yan ZY. Chaos 2005;15:023902] to study the generalized Q-S synchronization between the generalized Lorenz canonical form and the Roessler system, the more general controller is obtained. By choosing different parameter in the generalized controller obtained here, without much extra effort, we can get the controller of synchronization between the Chen system and the Roessler system, the Lue system and the Roessler system, the classic Lorenz system and the Roessler system, the Hyperbolic Lorenz system and the Roessler system, respectively. Finally, numerical simulations are used to perform such synchronization and verify the effectiveness of the controller.

  16. 43 CFR 4.100 - General rules and guidelines.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false General rules and guidelines. 4.100... rules and guidelines. (a) Effective date and applicability—(1) Effective date and general applicability..., in which event the period shall run to the end of the next business day. (e) General guidelines—(1...

  17. Slip effects on a generalized Burgers’ fluid flow between two side walls with fractional derivative

    Directory of Open Access Journals (Sweden)

    Shihao Han

    2016-01-01

    Full Text Available This paper presents a research for the 3D flow of a generalized Burgers’ fluid between two side walls generated by an exponential accelerating plate and a constant pressure gradient, where the no-slip assumption between the exponential accelerating plate and the Burgers’ fluid is no longer valid. The governing equations of the generalized Burgers’ fluid flow are established by using the fractional calculus approach. Exact analytic solutions for the 3D flow are established by employing the Laplace transform and the finite Fourier sine transform. Furthermore, some 3D and 2D figures for the fluid velocity and shear stress are plotted to analyze and discuss the effects of various parameters.

  18. [Effect of spatial location on the generality of block-wise conflict adaptation between different types of scripts].

    Science.gov (United States)

    Watanabe, Yurina; Yoshizaki, Kazuhito

    2014-10-01

    This study aimed to investigate the generality of conflict adaptation associated with block-wise conflict frequency between two types of stimulus scripts (Kanji and Hiragana). To this end, we examined whether the modulation of the compatibility effect with one type of script depending on block-wise conflict frequency (75% versus 25% generalized to the other type of script whose block-wise conflict frequency was kept constant (50%), using the Spatial Stroop task. In Experiment 1, 16 participants were required to identify the target orientation (up or down) presented in the upper or lower visual-field. The results showed that block-wise conflict adaptation with one type of stimulus script generalized to the other. The procedure in Experiment 2 was the same as that in Experiment 1, except that the presentation location differed between the two types of stimulus scripts. We did not find a generalization from one script to the other. These results suggest that presentation location is a critical factor contributing to the generality of block-wise conflict adaptation.

  19. A generalization of Friedman's rank statistic

    NARCIS (Netherlands)

    Kroon, de J.; Laan, van der P.

    1983-01-01

    In this paper a very natural generalization of the two·way analysis of variance rank statistic of FRIEDMAN is given. The general distribution-free test procedure based on this statistic for the effect of J treatments in a random block design can be applied in general two-way layouts without

  20. Effect of corticosteroid injection for trochanter pain syndrome: design of a randomised clinical trial in general practice

    Directory of Open Access Journals (Sweden)

    Verhaar Jan AN

    2007-09-01

    Full Text Available Abstract Background Regional pain in the hip in adults is a common cause of a general practitioner visit. A considerable part of patients suffer from (greater trochanteric pain syndrome or trochanteric bursitis. Local corticosteroid injections is one of the treatment options. Although clear evidence is lacking, small observational studies suggest that this treatment is effective in the short-term follow-up. So far, there are no randomised controlled trials available evaluating the efficacy of injection therapy. This study will investigate the efficacy of local corticosteroid injections in the trochanter syndrome in the general practice, using a randomised controlled trial design. The cost effectiveness of the corticosteroid injection therapy will also be assessed. Secondly, the role of co-morbidity in relation to the efficacy of local corticosteroid injections will be investigated. Methods/Design This study is a pragmatic, open label randomised trial. A total of 150 patients (age 18–80 years visiting the general practitioner with complaints suggestive of trochanteric pain syndrome will be allocated to receive local corticosteroid injections or to receive usual care. Usual care consists of analgesics as needed. The randomisation is stratified for yes or no co-morbidity of low back pain, osteoarthritis of the hip, or both. The treatment will be evaluated by means of questionnaires at several time points within one year, with the 3 month and 1 year evaluation of pain and recovery as primary outcome. Analyses of primary and secondary outcomes will be made according to the intention-to-treat principle. Direct and indirect costs will be assessed by questionnaires. The cost effectiveness will be estimated using the following ratio: CE ratio = (cost of injection therapy minus cost of usual care/(effect of injection therapy minus effect of usual care. Discussion This study design is appropriate to estimate effectiveness and cost-effectiveness of the

  1. Report from UNSCEAR to the United Nations General Assembly

    International Nuclear Information System (INIS)

    2001-01-01

    Over the past few years, the United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) has undertaken a broad review of the sources and effects of ionizing radiation. The result of this work has presented for the general reader in the 2000 Report to the General Assembly. This report with the supporting scientific annexes, which are aimed at the general scientific community, was published as 'Sources and Effects of Ionizing Radiation, United Nations Scientific Committee on the Effects of Atomic Radiation 2000 report to the General Assembly, with scientific annexes'

  2. The association of long-term treatment-related side effects with cancer-specific and general quality of life among prostate cancer survivors.

    Science.gov (United States)

    Davis, Kimberly M; Kelly, Scott P; Luta, George; Tomko, Catherine; Miller, Anthony B; Taylor, Kathryn L

    2014-08-01

    To examine the association between treatment-related side effects and cancer-specific and general quality of life (QOL) among long-term prostate cancer survivors. Within the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial, we conducted telephone interviews with prostate cancer survivors (N = 518) who were 5-10 years after diagnosis. We assessed demographic and clinical information, sexual, urinary, and bowel treatment-related side effects (Expanded Prostate Cancer Index Composite), cancer-specific QOL (Functional Assessment of Cancer Therapy--total score), and general QOL (the Medical Outcomes Study Short Form 12's physical and mental subscales). Participants were aged 74.6 years on average, primarily White (88.4%), and married (81.7%). Pearson correlation coefficients between the 3 treatment-related side effect domains (urinary, sexual, and bowel) and QOL ranged between 0.14 and 0.42 (P functioning and greater bowel side effects were independently associated with poorer cancer-specific QOL (P functions were also associated with poorer general QOL on the Medical Outcomes Study Short Form 12's physical component summary and mental component summary (P side effects demonstrated the strongest association with all QOL outcomes. Treatment-related side effects persisted for up to 10 years after diagnosis and continued to be associated with men's QOL. These results suggest that each of the treatment-related side effects was independently associated with cancer-specific QOL. Compared with the other Expanded Prostate Cancer Index Composite domains, bowel side effects had the strongest association with cancer-specific and general QOL. These associations emphasize the tremendous impact that bowel side effects continue to have for men many years after their initial diagnosis. Copyright © 2014. Published by Elsevier Inc.

  3. Context-dependent Generalization

    Directory of Open Access Journals (Sweden)

    Jordan A Taylor

    2013-05-01

    Full Text Available The pattern of generalization following motor learning can provide a probe on the neural mechanisms underlying learning. For example, the breadth of generalization to untrained regions of space after visuomotor adaptation to targets in a restricted region of space has been attributed to the directional tuning properties of neurons in the motor system. Building on this idea, the effect of different types of perturbations on generalization (e.g., rotation versus visual translation have been attributed to the selection of differentially tuned populations. Overlooked in this discussion is consideration of how the context of the training environment may constrain generalization. Here, we explore the role of context by having participants learn a visuomotor rotation or a translational shift in two different contexts, one in which the array of targets were presented in a circular arrangement and the other in which they were presented in a rectilinear arrangement. The perturbation and environments were either consistent (e.g., rotation with circular arrangement or inconsistent (e.g., rotation with rectilinear arrangement. The pattern of generalization across the workspace was much more dependent on the context of the environment than on the perturbation, with broad generalization for the rectilinear arrangement for both types of perturbations. Moreover, the generalization pattern for this context was evident, even when the perturbation was introduced in a gradual manner, precluding the use of an explicit strategy. We describe how current models of generalization might be modified to incorporate these results, building on the idea that context provides a strong bias for how the motor system infers the nature of the visuomotor perturbation and, in turn, how this information influences the pattern of generalization.

  4. The effect of music therapy compared with general recreational activities in reducing agitation in people with dementia: a randomised controlled trial.

    Science.gov (United States)

    Vink, A C; Zuidersma, M; Boersma, F; de Jonge, P; Zuidema, S U; Slaets, J P J

    2013-10-01

    This study aimed to compare the effects of music therapy with general recreational day activities in reducing agitation in people with dementia, residing in nursing home facilities. In a randomised controlled design, residents with dementia (n = 94) were allocated to either music therapy or recreational activities. Both music therapy and general activities were offered twice weekly for 4 months. Changes in agitation were measured with a modified Cohen-Mansfield Agitation Inventory (CMAI) at four intervals on each intervention day. A mixed model analysis was used to evaluate the effectiveness of music therapy, compared with general activities, on CMAI scores at 4 h after the intervention, controlled for CMAI scores at 1 h before the session and session number. Data were analysed for 77 residents (43 randomised to music therapy and 34 to general activities). In both groups, the intervention resulted in a decrease in agitated behaviours from 1 h before to 4 h after each session. This decrease was somewhat greater in the music therapy group than in the general activities group, but this difference was statistically not significant (F = 2.885, p = 0.090) and disappeared completely after adjustment for Global Deterioration Scale stage (F = 1.500; p = 0.222). Both music therapy and recreational activities lead to a short-term decrease in agitation, but there was no additional beneficial effect of music therapy over general activities. More research is required to provide insight in the effects of music therapy in reducing agitation in demented older people. Copyright © 2012 John Wiley & Sons, Ltd.

  5. The effects of cigarette smoking behavior and psychosis history on general and social cognition in bipolar disorder.

    Science.gov (United States)

    Ospina, Luz H; Russo, Manuela; Nitzburg, George M; Cuesta-Diaz, Armando; Shanahan, Megan; Perez-Rodriguez, Mercedes M; Mcgrath, Meaghan; Levine, Hannah; Mulaimovic, Sandra; Burdick, Katherine E

    2016-09-01

    Several studies have documented the prevalence and effects of cigarette smoking on cognition in psychotic disorders; fewer have focused on bipolar disorder (BD). Cognitive and social dysfunction are common in BD, and the severity of these deficits may be related both to illness features (e.g., current symptoms, psychosis history) and health-related behaviors (e.g., smoking, alcohol use). The current study assessed the influence of cigarette smoking on general and social cognition in a BD cohort, accounting for illness features with a focus on psychosis history. We assessed smoking status in 105 euthymic patients with BD, who completed a comprehensive battery including social (facial affect recognition, emotional problem-solving, and theory of mind) and general (the MATRICS Consensus Cognitive Battery and executive functioning) cognitive measures. We compared smokers vs nonsmokers on cognitive performance and tested for the effects of psychosis history, premorbid intellectual functioning, substance use, and current affective symptoms. Within the nonpsychotic subgroup with BD (n=45), smokers generally outperformed nonsmokers; by contrast, for subjects with BD with a history of psychosis (n=41), nonsmokers outperformed smokers. This pattern was noted more globally using a general composite cognitive score and on social/affective measures assessing patients' ability to identify emotions of facial stimuli and solve emotional problems. Cigarette smoking differentially affects performance on both general and social cognition in patients with BD as a function of psychosis history. These results suggest that there may be at least partially divergent underlying neurobiological causes for cognitive dysfunction in patients with BD with and without psychosis. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. Synergistic effect of age and body mass index on mortality and morbidity in general surgery.

    Science.gov (United States)

    Yanquez, Federico J; Clements, John M; Grauf, Dawn; Merchant, Aziz M

    2013-09-01

    The elderly population (aged 65 y and older) is expected to be the dominant age group in the United States by 2030. In addition, the prevalence of obesity in the United States is growing exponentially. Obese elderly patients are increasingly undergoing elective or emergent general surgery. There are few, if any, studies highlighting the combined effect of age and body mass index (BMI) on surgical outcomes. We hypothesize that increasing age and BMI synergistically impact morbidity and mortality in general surgery. We collected individual-level, de-identified patient data from the Michigan Surgical Quality Collaborative. Subjects underwent general surgery with general anesthetic, were >18 y, and had a BMI between 19 and 60. Primary and secondary outcomes were 30-d "Any morbidity" and mortality (from wound, respiratory, genitourinary, central nervous system, and cardiac systems), respectively. Preoperative risk variables included diabetes, dialysis, steroid use, cardiac risk, wound classification, American Society of Anesthesiology class, emergent cases, and 13 other variables. We conducted binary logistic regression models for 30-d morbidity and mortality to determine independent effects of age, BMI, interaction between both age and BMI, and a saturated model for all independent variables. We identified 149,853 patients. The average age was 54.6 y, and the average BMI was 30.9. Overall 30-d mortality was 2%, and morbidity was 6.7%. Age was a positive predictor for mortality and morbidity, and BMI was negatively associated with mortality and not significantly associated with morbidity. Age combined with higher BMI was positively associated with morbidity and mortality when the higher age groups were analyzed. Saturated models revealed age and American Society of Anesthesiology class as highest predictors of poor outcomes. Although BMI itself was not a major independent factor predicting 30-d major morbidity or mortality, the morbidly obese, elderly (>50 and 70 y

  7. The Thermodynamics of General and Local Anesthesia

    Science.gov (United States)

    Græsbøll, Kaare; Sasse-Middelhoff, Henrike; Heimburg, Thomas

    2014-05-01

    General anesthetics are known to cause depression of the freezing point of transitions in biomembranes. This is a consequence of ideal mixing of the anesthetic drugs in the membrane fluid phase and exclusion from the solid phase. Such a generic law provides physical justification of the famous Meyer-Overton rule. We show here that general anesthetics, barbiturates and local anesthetics all display the same effect on melting transitions. Their effect is reversed by hydrostatic pressure. Thus, the thermodynamic behavior of local anesthetics is very similar to that of general anesthetics. We present a detailed thermodynamic analysis of heat capacity profiles of membranes in the presence of anesthetics. This analysis is able to describe experimentally observed calorimetric profiles and permits prediction of the anesthetic features of arbitrary molecules. In addition, we discuss the thermodynamic origin of the cutoff-effect of long-chain alcohols and the additivity of the effect of general and local anesthetics.

  8. General contrast effects in speech perception: effect of preceding liquid on stop consonant identification.

    Science.gov (United States)

    Lotto, A J; Kluender, K R

    1998-05-01

    When members of a series of synthesized stop consonants varying acoustically in F3 characteristics and varying perceptually from /da/ to /ga/ are preceded by /al/, subjects report hearing more /ga/ syllables relative to when each member is preceded by /ar/ (Mann, 1980). It has been suggested that this result demonstrates the existence of a mechanism that compensates for coarticulation via tacit knowledge of articulatory dynamics and constraints, or through perceptual recovery of vocal-tract dynamics. The present study was designed to assess the degree to which these perceptual effects are specific to qualities of human articulatory sources. In three experiments, series of consonant-vowel (CV) stimuli varying in F3-onset frequency (/da/-/ga/) were preceded by speech versions or nonspeech analogues of /al/ and /ar/. The effect of liquid identity on stop consonant labeling remained when the preceding VC was produced by a female speaker and the CV syllable was modeled after a male speaker's productions. Labeling boundaries also shifted when the CV was preceded by a sine wave glide modeled after F3 characteristics of /al/ and /ar/. Identifications shifted even when the preceding sine wave was of constant frequency equal to the offset frequency of F3 from a natural production. These results suggest an explanation in terms of general auditory processes as opposed to recovery of or knowledge of specific articulatory dynamics.

  9. Effects of viscous pressure on warm inflationary generalized cosmic Chaplygin gas model

    Energy Technology Data Exchange (ETDEWEB)

    Sharif, M.; Saleem, Rabia, E-mail: msharif.math@pu.edu.pk, E-mail: rabiasaleem1988@yahoo.com [Department of Mathematics, University of the Punjab, Quaid-e-Azam Campus, Lahore-54590 (Pakistan)

    2014-12-01

    This paper is devoted to study the effects of bulk viscous pressure on an inflationary generalized cosmic Chaplygin gas model using FRW background. The matter contents of the universe are assumed to be inflaton and imperfect fluid. We evaluate inflaton fields, potentials and entropy density for variable as well as constant dissipation and bulk viscous coefficients in weak as well as high dissipative regimes during intermediate era. In order to discuss inflationary perturbations, we evaluate entropy density, scalar (tensor) power spectra, their corresponding spectral indices, tensor-scalar ratio and running of spectral index in terms of inflaton which are constrained using recent Planck, WMAP7 and Bicep2 probes.

  10. Effects of viscous pressure on warm inflationary generalized cosmic Chaplygin gas model

    International Nuclear Information System (INIS)

    Sharif, M.; Saleem, Rabia

    2014-01-01

    This paper is devoted to study the effects of bulk viscous pressure on an inflationary generalized cosmic Chaplygin gas model using FRW background. The matter contents of the universe are assumed to be inflaton and imperfect fluid. We evaluate inflaton fields, potentials and entropy density for variable as well as constant dissipation and bulk viscous coefficients in weak as well as high dissipative regimes during intermediate era. In order to discuss inflationary perturbations, we evaluate entropy density, scalar (tensor) power spectra, their corresponding spectral indices, tensor-scalar ratio and running of spectral index in terms of inflaton which are constrained using recent Planck, WMAP7 and Bicep2 probes

  11. The effects of general anaesthesia on memory in children: a comparison between propofol and sevoflurane.

    Science.gov (United States)

    Yin, J; Wang, S-L; Liu, X-B

    2014-02-01

    We studied the effects of general anaesthesia on memory 7 days and 3 months following elective hernia surgery. Sixty children aged between 7 and 13 years were randomly allocated to receive either propofol or sevoflurane. Memory was classified into immediate, short-term and long-term memory and assessed using the Wechsler Memory Scale-Propofol impaired short-term memory 7 days postoperatively compared with pre-operative values (image recalling: p = 0.02, figure recognition: p = 0.01, visual reproduction: p = 0.03) but recovered to baseline levels 3 months following surgery. Neither general anaesthetic affected immediate or long-term memory. We conclude that propofol impairs short-term memory postoperatively in children. © 2013 The Association of Anaesthetists of Great Britain and Ireland.

  12. ENERGY AND CONSTRUCTION CONDITIONS OF THE EFFECTIVENESS OF APPAATUS FOR GENERAL CRYOTHERAPEUTIC IMPACT

    Directory of Open Access Journals (Sweden)

    A. U. Baranov

    2016-01-01

    Full Text Available Objectives. To evaluate the correspondence of construction and power consumption of Cryotherapeutic Complexes (CTC with technological conditions of effectiveness of the General Cryotherapeutic Impact (GCI. Methods. The associated analysis method used Cryotherapeutic Complexes (CTC construction and power consumption with technological conditions of effectiveness of the General Cryotherapeutic Impact (GCI. Results. An explanation for the discrepancy of observations of different researchers in differences in design and available power of the CTC is proposed. The technical operating characteristics of single-seat and multi-seat CTC are provided and these significant differences in apparatus of identical technological designation are illustrated. The proposed system of specific CTC characteristics is capable of unifying their basic structural and energy characteristics. Calculation of the specific characteristics of existing systems showed that between objects of the same designation, there are differences in value, which may be the cause of discrepancies in their therapeutic efficacy. All functional CPC have a cryostatting cooling capacity system deficit of between 8 and 75%. In multi-seat CPC cooling capacity deficit exceeds 50%, which excludes the possibility of obtaining a significant therapeutic effect, as is confirmed by the results of independent studies that show that the procedures in multi-seat CTC safeguards skin from frigorism only up to 14°C, while at the same time for effective OKV frigorism of the skin surface is necessary to a temperature of less than about 2°C. Prior to research on the effectiveness of OKV, it is necessary to assess the energy consumption conformity of cryotherapy equipment. Conclusion. For the successful implementation of OKV in medicine and sport, it is necessary to increase energy efficiency and optimise cryotherapeutic temperature control settings. A cryotheraputic complex should safeguard such physical

  13. The Effect of Sleep on Children’s Word Retention and Generalization

    Directory of Open Access Journals (Sweden)

    Emma L. Axelsson

    2016-08-01

    Full Text Available In the first few years of life children spend a good proportion of time sleeping as well as acquiring the meanings of hundreds of words and their related associations. There is now ample evidence of the effects of sleep on memory in adults and the number of studies demonstrating the effects of napping and nocturnal sleep in children is also mounting. In particular, sleep appears to benefit children’s memory for recently-encountered novel words. The effect of sleep on children’s generalization of novel words across multiple items, however, is less clear. Given that sleep is polyphasic in the early years, made up of multiple episodes, and children’s word learning is gradual and strengthened slowly over time, it is highly plausible that sleep is a strong candidate in supporting children’s memory for novel words. Importantly, it appears that when children sleep shortly after exposure to novel word-object pairs retention is better than if sleep is delayed, suggesting that napping plays a vital role in long-term word retention for young children. Word learning is a complex, challenging and important part of development, thus the role that sleep plays in children’s retention of novel words is worthy of attention. As such, ensuring children get sufficient good quality sleep and regular opportunities to nap may be critical for strong language acquisition.

  14. Rebound effect of improved energy efficiency for different energy types: A general equilibrium analysis for China

    International Nuclear Information System (INIS)

    Lu, Yingying; Liu, Yu; Zhou, Meifang

    2017-01-01

    This paper explores the rebound effect of different energy types in China based on a static computable general equilibrium model. A one-off 5% energy efficiency improvement is imposed on five different types of energy, respectively, in all the 135 production sectors in China. The rebound effect is measured both on the production level and on the economy-wide level for each type of energy. The results show that improving energy efficiency of using electricity has the largest positive impact on GDP among the five energy types. Inter-fuel substitutability does not affect the macroeconomic results significantly, but long-run impact is usually greater than the short-run impact. For the exports-oriented sectors, those that are capital-intensive get big negative shock in the short run while those that are labour-intensive get hurt in the long run. There is no “backfire” effect; however, improving efficiency of using electricity can cause negative rebound, which implies that improving the energy efficiency of using electricity might be a good policy choice under China's current energy structure. In general, macro-level rebound is larger than production-level rebound. Primary energy goods show larger rebound effect than secondary energy goods. In addition, the paper points out that the policy makers in China should look at the rebound effect in the long term rather than in the short term. The energy efficiency policy would be a good and effective policy choice for energy conservation in China when it still has small inter-fuel substitution. - Highlights: • Primary energy goods show larger rebound effect than secondary energy goods. • Improving efficiency of using electricity can cause negative rebound. • The energy efficiency policy would be an effective policy choice for China. • Policy-makers should consider the rebound effect in the longer term.

  15. Flux compactifications and generalized geometries

    International Nuclear Information System (INIS)

    Grana, Mariana

    2006-01-01

    Following the lectures given at CERN Winter School 2006, we present a pedagogical overview of flux compactifications and generalized geometries, concentrating on closed string fluxes in type II theories. We start by reviewing the supersymmetric flux configurations with maximally symmetric four-dimensional spaces. We then discuss the no-go theorems (and their evasion) for compactifications with fluxes. We analyse the resulting four-dimensional effective theories for Calabi-Yau and Calabi-Yau orientifold compactifications, concentrating on the flux-induced superpotentials. We discuss the generic mechanism of moduli stabilization and illustrate with two examples: the conifold in IIB and a T 6 /(Z 3 x Z 3 ) torus in IIA. We finish by studying the effective action and flux vacua for generalized geometries in the context of generalized complex geometry

  16. Flux compactifications and generalized geometries

    Energy Technology Data Exchange (ETDEWEB)

    Grana, Mariana [Service de Physique Theorique, CEA/Saclay, 91191 Gif-sur-Yvette Cedex (France)

    2006-11-07

    Following the lectures given at CERN Winter School 2006, we present a pedagogical overview of flux compactifications and generalized geometries, concentrating on closed string fluxes in type II theories. We start by reviewing the supersymmetric flux configurations with maximally symmetric four-dimensional spaces. We then discuss the no-go theorems (and their evasion) for compactifications with fluxes. We analyse the resulting four-dimensional effective theories for Calabi-Yau and Calabi-Yau orientifold compactifications, concentrating on the flux-induced superpotentials. We discuss the generic mechanism of moduli stabilization and illustrate with two examples: the conifold in IIB and a T{sup 6} /(Z{sub 3} x Z{sub 3}) torus in IIA. We finish by studying the effective action and flux vacua for generalized geometries in the context of generalized complex geometry.

  17. STRONG FIELD EFFECTS ON PULSAR ARRIVAL TIMES: GENERAL ORIENTATIONS

    International Nuclear Information System (INIS)

    Wang Yan; Creighton, Teviet; Price, Richard H.; Jenet, Frederick A.

    2009-01-01

    A pulsar beam passing close to a black hole can provide a probe of very strong gravitational fields even if the pulsar itself is not in a strong field region. In the case that the spin of the hole can be ignored, we have previously shown that all strong field effects on the beam can be understood in terms of two 'universal' functions: F(φ in ) and T(φ in ) of the angle of beam emission φ in ; these functions are universal in that they depend only on a single parameter, the pulsar/black hole distance from which the beam is emitted. Here we apply this formalism to general pulsar-hole-observer geometries, with arbitrary alignment of the pulsar spin axis and arbitrary pulsar beam direction and angular width. We show that the analysis of the observational problem has two distinct elements: (1) the computation of the location and trajectory of an observer-dependent 'keyhole' direction of emission in which a signal can be received by the observer; and (2) the determination of an annulus that represents the set of directions containing beam energy. Examples of each are given along with an example of a specific observational scenario.

  18. Generalized, Linear, and Mixed Models

    CERN Document Server

    McCulloch, Charles E; Neuhaus, John M

    2011-01-01

    An accessible and self-contained introduction to statistical models-now in a modernized new editionGeneralized, Linear, and Mixed Models, Second Edition provides an up-to-date treatment of the essential techniques for developing and applying a wide variety of statistical models. The book presents thorough and unified coverage of the theory behind generalized, linear, and mixed models and highlights their similarities and differences in various construction, application, and computational aspects.A clear introduction to the basic ideas of fixed effects models, random effects models, and mixed m

  19. Generalized Rosenbluth potentials

    International Nuclear Information System (INIS)

    Hassan, M.H.A.

    1977-05-01

    It is shown that the coefficients of friction and diffusion of the Balescu-Lenard equation can be derived from two ''generalized Rosenbluth potentials'', which reduce to the standard Rosenbluth potentials if wave effects are neglected. The potentials are evaluated explicitly in the case of Maxwellian field particles. The dominant contribution of wave effects to the potentials is due to the interaction of electron field particles with ion sound waves

  20. SSD with generalized phase modulation

    International Nuclear Information System (INIS)

    Rothenberg, J.

    1996-01-01

    Smoothing by spectral dispersion (SSD) with standard frequency modulation (FM), although simple to implement, has the disadvantage that low spatial frequencies present in the spectrum of the target illumination are not smoothed as effectively as with a more general smoothing method (eg, induced spatial incoherence method). The reduced smoothing performance of standard FM-SSD can result in spectral power of the speckle noise at these low spatial frequencies as much as one order of magnitude larger than that achieved with a more general method. In fact, at small integration times FM-SSD has no smoothing effect at all for a broad band of low spatial frequencies. This effect may have important implications for both direct and indirect drive ICF

  1. Effects produced by oscillations applied to nonlinear dynamic systems: a general approach and examples

    DEFF Research Database (Denmark)

    Blekhman, I. I.; Sorokin, V. S.

    2016-01-01

    A general approach to study effects produced by oscillations applied to nonlinear dynamic systems is developed. It implies a transition from initial governing equations of motion to much more simple equations describing only the main slow component of motions (the vibro-transformed dynamics.......g., the requirement for the involved nonlinearities to be weak. The approach is illustrated by several relevant examples from various fields of science, e.g., mechanics, physics, chemistry and biophysics....... equations). The approach is named as the oscillatory strobodynamics, since motions are perceived as under a stroboscopic light. The vibro-transformed dynamics equations comprise terms that capture the averaged effect of oscillations. The method of direct separation of motions appears to be an efficient...

  2. Effects of Horticultural Ttherapy on Self-Esteem and General Health Status in Elderly Nursing Home Residents

    Directory of Open Access Journals (Sweden)

    Zahra Dehmani

    2015-01-01

    Full Text Available Objectives: The present study investigated the effectiveness of horticultural therapy on increasing of self esteem and general health in seniors. Methods & Materials: The study design was semi experimental. The study population was all of seniors that lived in nursing home residents of Tehran in 1392 that 24 of them were selected by convenience sampling method. Then, we assigned them in control (12 people and experimental (12 people groups. For gathering data we used Cooper Smith self-esteem inventory and General Health Questionnaires (GHQ. The entry criteria were obtaining low score in self esteem inventory and obtaining high score in General Health Questionnaire. Also exit criteria were relinquishment of any of subjects to continue of research process. The experimental group was exposed to 13 sessions of gardening instruction and all equipment of gardening provided by researcher for all of groups’ members. Then, both groups completed mentioned tools twice at the end of gardening therapy: at the post test and follow up stage (3 month later. Data analysis was performed by using of variance with repeated measures. Results: results showed that there is a significant difference between mean scores of general health and self esteem in post test and follow up stages compared to pre test stage. In other words, gardening therapy for increasing of self esteem and general health in seniors has been successful. Conclusion: Horticultural therapy can improves general health and self esteem of seniors who living in nursing homes. Also as a non-drug treatment and low cost for other groups of patients is recommended.

  3. Implicit and Explicit Attitudes Toward Spiders : Sensitivity to Treatment and Predictive Value for Generalization of Treatment Effects

    NARCIS (Netherlands)

    Huijding, Jorg; de Jong, Peter J.

    This study tested whether high spider fearful individuals' implicit and explicit attitudes toward spiders are sensitive to exposure treatment, and whether post-treatment implicit and/or explicit attitudes are related to the generalization of treatment effects. Self-reported explicit and implicit

  4. General approach to the computation of local transport coefficients with finite Larmor effects in the collision contribution

    International Nuclear Information System (INIS)

    Ghendrih, P.

    1986-10-01

    We expand the distribution functions on a basis of Hermite functions and obtain a general scheme to compute the local transport coefficients. The magnetic field dependence due to finite Larmor radius effects during the collision process is taken into account

  5. Lack of gender effects on gray matter volumes in adolescent generalized anxiety disorder.

    Science.gov (United States)

    Liao, Mei; Yang, Fan; Zhang, Yan; He, Zhong; Su, Linyan; Li, Lingjiang

    2014-02-01

    Previous epidemiological and clinical studies have reported gender differences in prevalence and clinical features of generalized anxiety disorder (GAD). Such gender differences in clinical phenomenology suggest that the underlying neural circuitry of GAD could also be different in males and females. This study aimed to explore the possible gender effect on gray matter volumes in adolescents with GAD. Twenty-six adolescent GAD patients and 25 healthy controls participated and underwent high-resolution structural magnetic resonance scans. Voxel-based morphometry (VBM) was used to investigate gray matter alterations. Our study revealed a significant diagnosis main effect in the right putamen, with larger gray matter volumes in GAD patients compared to healthy controls, and a significant gender main effect in the left precuneus/posterior cingulate cortex, with larger gray matter volumes in males compared to females. No gender-by-diagnosis interaction effect was found in this study. The relatively small sample size in this study might result in a lack of power to demonstrate gender effects on brain structure in GAD. The results suggested that there are differences in gray matter volumes between males and females, but gray matter volumes in GAD are not influenced by gender. © 2013 Published by Elsevier B.V.

  6. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... transducer sends out high-frequency sound waves (that the human ear cannot hear) into the body and then ... ultrasound , there are no known harmful effects on humans. top of page What are the limitations of General Ultrasound Imaging? Ultrasound waves are ...

  7. Multivariate generalized linear mixed models using R

    CERN Document Server

    Berridge, Damon Mark

    2011-01-01

    Multivariate Generalized Linear Mixed Models Using R presents robust and methodologically sound models for analyzing large and complex data sets, enabling readers to answer increasingly complex research questions. The book applies the principles of modeling to longitudinal data from panel and related studies via the Sabre software package in R. A Unified Framework for a Broad Class of Models The authors first discuss members of the family of generalized linear models, gradually adding complexity to the modeling framework by incorporating random effects. After reviewing the generalized linear model notation, they illustrate a range of random effects models, including three-level, multivariate, endpoint, event history, and state dependence models. They estimate the multivariate generalized linear mixed models (MGLMMs) using either standard or adaptive Gaussian quadrature. The authors also compare two-level fixed and random effects linear models. The appendices contain additional information on quadrature, model...

  8. Effect of Generalized Uncertainty Principle on Main-Sequence Stars and White Dwarfs

    Directory of Open Access Journals (Sweden)

    Mohamed Moussa

    2015-01-01

    Full Text Available This paper addresses the effect of generalized uncertainty principle, emerged from different approaches of quantum gravity within Planck scale, on thermodynamic properties of photon, nonrelativistic ideal gases, and degenerate fermions. A modification in pressure, particle number, and energy density are calculated. Astrophysical objects such as main-sequence stars and white dwarfs are examined and discussed as an application. A modification in Lane-Emden equation due to a change in a polytropic relation caused by the presence of quantum gravity is investigated. The applicable range of quantum gravity parameters is estimated. The bounds in the perturbed parameters are relatively large but they may be considered reasonable values in the astrophysical regime.

  9. Effects of general relativity in the motion of minor planets and comets

    International Nuclear Information System (INIS)

    Sitarski, G.

    1983-01-01

    Basing on the solution of one-body Schwarzschild problem, the relativistic terms were included to the equations of motion of a minor planet or comet. It appeared that the using of Painleve's coordinates allowed to write the equations of motion in a very simple form. Equations of motion as well as the commonly used equations based on the Schwarzschild isotropic and nonisotropic line elements were numerically integrated by the recurrent power series method. The results of integration of the motion of Mercury and of the minor planet Icarus show strictly the perihelion motion predicted by the general relativity theory. The relativistic effects in the motion of some minor planets and comets were examined too. (author)

  10. Effectiveness of social work intervention with a systematic approach to improve general health in opioid addicts in addiction treatment centers.

    Science.gov (United States)

    Raheb, Ghoncheh; Khaleghi, Esmat; Moghanibashi-Mansourieh, Amir; Farhoudian, Ali; Teymouri, Robab

    2016-01-01

    This study takes a systematic approach to investigate the effect of social work intervention aimed at increasing general health among opioid addicts in addiction treatment centers. This is an experimental plan (pretest to posttest with a control group); the study sample included 60 patients with drug dependencies undergoing treatment in addiction treatment centers. These patients were randomly assigned as case (30) and control (30) groups. The case group was subjected to intervention over ten sessions, whereas the control group received no intervention. Both groups then passed through a posttest, while a follow-up was conducted after 4 months. Data were obtained via a General Health Questionnaire. A covariance analysis test and independent and dependent t -test results indicated that a social work intervention adopting systematic approach was effective in increasing the general health of drug-addicted patients under treatment. Thus, the nature of the presence of social workers in addiction treatment centers has been effective and can have a significant influence by reducing anxiety and insomnia and somatic symptoms, improving patients' self-understanding and self-recognition, and enhancing social functioning.

  11. The positive effect on determinants of physical activity of a tailored, general practice-based physical activity intervention

    NARCIS (Netherlands)

    van Sluijs, E.M.F.; van Poppel-Bruinvels, M.N.M.; Twisk, J.W.R.; Brug, J.; van Mechelen, W.

    2005-01-01

    PACE (Physician-based Assessment and Counseling for Exercise) is an individualized theory-based minimal intervention strategy aimed at the enhancement of regular physical activity. The aim of this study was to evaluate the effectiveness of a PACE intervention applied by general practitioners (GPs)

  12. Extending the linear model with R generalized linear, mixed effects and nonparametric regression models

    CERN Document Server

    Faraway, Julian J

    2005-01-01

    Linear models are central to the practice of statistics and form the foundation of a vast range of statistical methodologies. Julian J. Faraway''s critically acclaimed Linear Models with R examined regression and analysis of variance, demonstrated the different methods available, and showed in which situations each one applies. Following in those footsteps, Extending the Linear Model with R surveys the techniques that grow from the regression model, presenting three extensions to that framework: generalized linear models (GLMs), mixed effect models, and nonparametric regression models. The author''s treatment is thoroughly modern and covers topics that include GLM diagnostics, generalized linear mixed models, trees, and even the use of neural networks in statistics. To demonstrate the interplay of theory and practice, throughout the book the author weaves the use of the R software environment to analyze the data of real examples, providing all of the R commands necessary to reproduce the analyses. All of the ...

  13. Anxiolytic and antidepressive effects of magnesium in rats and their effect on general behavioural parameters

    Directory of Open Access Journals (Sweden)

    Samardžić Janko

    2011-01-01

    Full Text Available Magnesium (Mg is an essential element that catalyses more than 300 enzyme systems. Its effects on the central nervous system are exhibited through the blocking of activity of N-methyl D-aspartat (NMDA receptors and potentiating of GABA-ergic neurotransmission. Due to the vast importance of these two neurotransmission systems in the fine regulation of the central integrative function activity, the aim of this research was to test the anxiolytic and antidepressive effects of magnesium, after acute and repeated application, and its influence on general behavioural parameters. In this research Wistar albino rats were treated with increasing doses of Mg chloride 6-hydrate (MgCl 10, 20, 30 mg/kg. In order to determine anxiolytic and antidepressive properties of magnesium two models were used: elevated plus maze (EPM and forced swim test (FST. Behavioural parameters (stillness and mobility were recorded during acute and repeated administration of the active substance. Results of EPM testing showed no significant difference between groups, p>0.05. After acute application of increasing doses of magnesium chloride hydrate in FST, we showed the statistically significant difference in immobility time between the group of animals treated with Mg and the control group treated with the solvent, p<0.01. The statistically significant difference between groups treated with the lowest and the middle dose of magnesium and the controls was observed already on the first day of examining behavioural parameters (p=0.020, p=0.010. Our research has showed that magnesium, following acute administration, increases locomotor activity, and has an antidepressive but not an anxiolytic effect.

  14. Effects of HD-tDCS on memory and metamemory for general knowledge questions that vary by difficulty

    Science.gov (United States)

    Chua, Elizabeth F.; Ahmed, Rifat; Garcia, Sandry

    2016-01-01

    Background The ability to monitor one’s own memory is an important feature of normal memory and is an aspect of ‘metamemory’. Lesion studies have shown dissociations between memory and metamemory, but only single dissociations have been shown using transcranial direct current stimulation (tDCS). One potential reason that only single dissociations have been shown is that tDCS effects may be moderated by task difficulty. Objective/Hypothesis We used high definition (HD) tDCS to test for dissociable roles of the dorsolateral prefrontal cortex (DLPFC) and anterior temporal lobe (ATL) in semantic long-term memory and metamemory tasks. We also tested whether general knowledge question difficulty moderated the effects of HD-tDCS. Methods Across 3 sessions, participants received active HD-tDCS over the left DLPFC or left ATL, or sham HD-tDCS during general knowledge recall and recognition tests, and a ‘feeling-of-knowing’ metamemory task. General knowledge questions were blocked by difficulty. Repeated measures ANOVAs were used to examine the effects of HD-tDCS on memory and metamemory tasks by memory question difficulty. Results HD-tDCS over the ATL led to improved recall compared to DLPFC and sham HD-tDCS, and this occurred only for medium difficulty questions. In contrast, for non-recalled questions, HD-tDCS over the DLPFC led to improved recognition accuracy and improved feeling-of-knowing accuracy compared to ATL and sham HD-tDCS, and this was not moderated by memory question difficulty. Conclusion(s) HD-tDCS can be used to dissociate the roles of the ATL and DLPFC in different memory and ‘metamemory’ tasks. The effects of HD-tDCS on task may be moderated by task difficulty, depending on the nature of the task and site of stimulation. PMID:27876306

  15. The Effects of Incidental Teaching on the Generalized Use of Social Amenities at School by a Mildly Handicapped Adolescent

    OpenAIRE

    Oswald, L. K.; Lignugaris/Kraft, Benjamin; West, R.

    1990-01-01

    Recently, researchers have begun exploring the effects of incidental teaching on the acquisition of socially appropriate behavior by handicapped children and adults. The results of these investigations suggest that incidental teaching may facilitate the generalization of newly trained social skills. This study used incidental teaching procedures to teach a 16-year-old mildly handicapped student to use social amenities in a resource classroom. In addition, generalization was assessed to anothe...

  16. General constraints on the effect of gas flows in the chemical evolution of galaxies

    International Nuclear Information System (INIS)

    Edmunds, M.G.

    1990-01-01

    The basic equations for the chemical evolution of galaxies in which the 'simple' closed box model is modified to allow any form of inflow or outflow are examined. It is found that there are quite general limiting constraints on the effects that such flows can have. Some implications for the actual chemical evolution of galaxies are discussed, and the constraints should also be useful in understanding the behaviour of detailed numerical models of galactic chemical evolution involving gas flows. (author)

  17. Effective description of general extensions of the Standard Model: the complete tree-level dictionary

    Science.gov (United States)

    de Blas, J.; Criado, J. C.; Pérez-Victoria, M.; Santiago, J.

    2018-03-01

    We compute all the tree-level contributions to the Wilson coefficients of the dimension-six Standard-Model effective theory in ultraviolet completions with general scalar, spinor and vector field content and arbitrary interactions. No assumption about the renormalizability of the high-energy theory is made. This provides a complete ultraviolet/infrared dictionary at the classical level, which can be used to study the low-energy implications of any model of interest, and also to look for explicit completions consistent with low-energy data.

  18. Curvature Effects on the Vibration Characteristics of Doubly Curved Shallow Shells with General Elastic Edge Restraints

    Directory of Open Access Journals (Sweden)

    Hui Shi

    2015-01-01

    Full Text Available Effects of curvature upon the vibration characteristics of doubly curved shallow shells are assessed in this paper. Boundary conditions of the shell are generally specified in terms of distributed elastic restraints along the edges. The classical homogeneous boundary supports can be easily simulated by setting the stiffnesses of restraining springs to either zero or infinite. Vibration problems of the shell are solved by a modified Fourier series method that each of the displacements is invariably expressed as a simple trigonometric series which converges uniformly and acceleratedly over the solution domain. All the unknown expansion coefficients are treated equally as a set of independent generalized coordinates and solved using the Rayleigh-Ritz technique. The current method provides a unified solution to the vibration problems of curved shallow shells involving different geometric properties and boundary conditions with no need of modifying the formulations and solution procedures. Extensive tabular and graphical results are presented to show the curvature effects on the natural frequencies of the shell with various boundary conditions.

  19. General analysis for experimental studies of time-reversal-violating effects in slow neutron propagation through polarized matter

    International Nuclear Information System (INIS)

    Lamoreaux, S.K.; Golub, R.

    1994-01-01

    A general technique is developed for the analysis of proposed experimental studies of possible P,T-violating effects in the neutron-nucleus interaction based on low-energy neutron transmission through polarized matter. The analysis is applied to proposed experimental schemes and we determine the levels at which the absolute neutron polarization, magnetic fields, and target polarization must be controlled in order for these experiments to obtain a given sensitivity to P,T-violating effects

  20. Computing generalized Langevin equations and generalized Fokker-Planck equations.

    Science.gov (United States)

    Darve, Eric; Solomon, Jose; Kia, Amirali

    2009-07-07

    The Mori-Zwanzig formalism is an effective tool to derive differential equations describing the evolution of a small number of resolved variables. In this paper we present its application to the derivation of generalized Langevin equations and generalized non-Markovian Fokker-Planck equations. We show how long time scales rates and metastable basins can be extracted from these equations. Numerical algorithms are proposed to discretize these equations. An important aspect is the numerical solution of the orthogonal dynamics equation which is a partial differential equation in a high dimensional space. We propose efficient numerical methods to solve this orthogonal dynamics equation. In addition, we present a projection formalism of the Mori-Zwanzig type that is applicable to discrete maps. Numerical applications are presented from the field of Hamiltonian systems.

  1. Simple implementation of general dark energy models

    International Nuclear Information System (INIS)

    Bloomfield, Jolyon K.; Pearson, Jonathan A.

    2014-01-01

    We present a formalism for the numerical implementation of general theories of dark energy, combining the computational simplicity of the equation of state for perturbations approach with the generality of the effective field theory approach. An effective fluid description is employed, based on a general action describing single-scalar field models. The formalism is developed from first principles, and constructed keeping the goal of a simple implementation into CAMB in mind. Benefits of this approach include its straightforward implementation, the generality of the underlying theory, the fact that the evolved variables are physical quantities, and that model-independent phenomenological descriptions may be straightforwardly investigated. We hope this formulation will provide a powerful tool for the comparison of theoretical models of dark energy with observational data

  2. 28 CFR 0.168 - Redelegation by Assistant Attorneys General.

    Science.gov (United States)

    2010-07-01

    ..., Penalties, and Forfeitures § 0.168 Redelegation by Assistant Attorneys General. (a) Assistant Attorneys... the Assistant Attorney General level must be presented to the Assistant Attorney General for... the Deputy Attorney General or the Associate Attorney General, as appropriate, before taking effect...

  3. Memory and Comprehension for Health Information among Older Adults: Distinguishing the Effects of Domain-General and Domain-Specific Knowledge

    Science.gov (United States)

    Chin, Jessie; Payne, Brennan; Gao, Xuefei; Conner-Garcia, Thembi; Graumlich, James F.; Murray, Michael D.; Morrow, Daniel G.; Stine-Morrow, Elizabeth A.L.

    2014-01-01

    While there is evidence that knowledge influences understanding of health information, less is known about the processing mechanisms underlying this effect and its impact on memory. We used the moving window paradigm to examine how older adults varying in domain-general crystallized ability (verbal ability) and health knowledge allocate attention to understand health and domain-general texts. Participants (n=107, aged 60 to 88 yrs) read and recalled single sentences about hypertension and about non-health topics. Mixed-effects modeling of word-by-word reading times suggested that domain-general crystallized ability increased conceptual integration regardless of text domain, while health knowledge selectively increased resource allocation to conceptual integration at clause boundaries in health texts. These patterns of attentional allocation were related to subsequent recall performance. Although older adults with lower levels of crystallized ability were less likely to engage in integrative processing, when they did, this strategy had a compensatory effect in improving recall. These findings suggest that semantic integration during reading is an important comprehension process that supports the construction of the memory representation and is engendered by knowledge. Implications of the findings for theories of text processing and memory as well as for designing patient education materials are discussed. PMID:24787361

  4. Memory and comprehension for health information among older adults: distinguishing the effects of domain-general and domain-specific knowledge.

    Science.gov (United States)

    Chin, Jessie; Payne, Brennan; Gao, Xuefei; Conner-Garcia, Thembi; Graumlich, James F; Murray, Michael D; Morrow, Daniel G; Stine-Morrow, Elizabeth A L

    2015-01-01

    While there is evidence that knowledge influences understanding of health information, less is known about the processing mechanisms underlying this effect and its impact on memory. We used the moving window paradigm to examine how older adults varying in domain-general crystallised ability (verbal ability) and health knowledge allocate attention to understand health and domain-general texts. Participants (n = 107, age: 60-88 years) read and recalled single sentences about hypertension and about non-health topics. Mixed-effects modelling of word-by-word reading times suggested that domain-general crystallised ability increased conceptual integration regardless of text domain, while health knowledge selectively increased resource allocation to conceptual integration at clause boundaries in health texts. These patterns of attentional allocation were related to subsequent recall performance. Although older adults with lower levels of crystallised ability were less likely to engage in integrative processing, when they did, this strategy had a compensatory effect in improving recall. These findings suggest that semantic integration during reading is an important comprehension process that supports the construction of the memory representation and is engendered by knowledge. Implications of the findings for theories of text processing and memory as well as for designing patient education materials are discussed.

  5. Virtual Photon Effects on Chaos in Generalized Lorenz-Haken Equation

    International Nuclear Information System (INIS)

    Ju Rui; Huang Hongbin; Yang Peng; Xie Xia; Zhao Huan

    2005-01-01

    The dynamics of an ensemble of two-level atoms injected into a single-mode cavity is studied in the exact atom-field interaction situation, in which the counter-rotating terms describing the so-called virtual photon processes neglected in the rotating-wave approximation, are considered. The cavity mode is driven by the injected classical field, and the atom is prepared in a coherent superposition of the two levels. We first derive the generalized Lorenz-Haken equation by using the technique of quantum Langevin equation, and then numerically study the dynamics of this equation. We find that the virtual photon processes have strong effects on the dynamics, which can cause the trajectory in phase space of strange attractor spiral around four focus points, and the trajectory is modulated by virtual photon processes. The chaos region in parameter space is now enlarged. It should be stressed that the strange attractor can exist in optical bistability, and whether the atomic coherences and classical field can inhibit chaos depends on the laser frequency.

  6. The FPGA realization of the general cellular automata based cryptographic hash functions: Performance and effectiveness

    Directory of Open Access Journals (Sweden)

    P. G. Klyucharev

    2014-01-01

    Full Text Available In the paper the author considers hardware implementation of the GRACE-H family general cellular automata based cryptographic hash functions. VHDL is used as a language and Altera FPGA as a platform for hardware implementation. Performance and effectiveness of the FPGA implementations of GRACE-H hash functions were compared with Keccak (SHA-3, SHA-256, BLAKE, Groestl, JH, Skein hash functions. According to the performed tests, performance of the hardware implementation of GRACE-H family hash functions significantly (up to 12 times exceeded performance of the hardware implementation of previously known hash functions, and effectiveness of that hardware implementation was also better (up to 4 times.

  7. The effect of Malaysia general election on stock market returns

    OpenAIRE

    Liew, Venus Khim-Sen; Rowland, Racquel

    2016-01-01

    During the latest episode of general election held in Malaysia, it is observed that the FBMKLCI index was lifted 62.52 points in a day soon after the announcement of election outcome. Moreover, the index registered a highest gain of 96.29 points in the middle of the intra-day trade. This suggests that investors who had got the right direction could make profitable intra-day trading the next trading day of the general election date. Results from statistical analysis uncover significant before-...

  8. General self-efficacy and the effect of hospital workplace violence on doctors' stress and job satisfaction in China.

    Science.gov (United States)

    Yao, Yongcheng; Wang, Wei; Wang, Faxuan; Yao, Wu

    2014-06-01

    This study aims at exploring associations of general self-efficacy (GSE), workplace violence and doctors' work-related attitudes. In this study a cross-sectional survey design was applied. Questionnaires were administrated to 758 doctors working in 9 hospitals of Zhengzhou, Henan province, China, between June and October 2010. General information on age, gender, and years of working was collected, and the doctors' experience and witnessing workplace violence, job satisfaction, job initiative, occupational stress as well as GSE were measured. General linear regression analysis was performed in association analyses. Both experiencing and witnessing workplace violence were significantly positively correlated with the level of occupational stress but significantly negatively correlated with job satisfaction, job initiative, and GSE. General self-efficacy significantly modified relationships between both experiencing and witnessing workplace violence with occupational stress (β = 0.49 for experiencing violence; β = 0.43 for witnessing violence; p violence with job initiative (p > 0.05). The levels of occupational stress declined significantly with the increase of GSE, while job satisfaction increased significantly along with its increase. The effects of GSE on occupational stress and job satisfaction weakened as the frequency of violence increased. The findings suggest that GSE can modify effects of workplace violence on health care workers' stress and job satisfaction. Enhancing GSE in combination with stress reduction may lead to facilitating health care workers' recovery from workplace violence, and thereby improving their work-related attitudes.

  9. General self-efficacy and the effect of hospital workplace violence on doctors’ stress and job satisfaction in China

    Directory of Open Access Journals (Sweden)

    Yongcheng Yao

    2014-08-01

    Full Text Available Objectives: This study aims at exploring associations of general self-efficacy (GSE, workplace violence and doctors' work-related attitudes. Material and Methods: In this study a cross-sectional survey design was applied. Questionnaires were administrated to 758 doctors working in 9 hospitals of Zhengzhou, Henan province, China, between June and October 2010. General information on age, gender, and years of working was collected, and the doctors' experience and witnessing workplace violence, job satisfaction, job initiative, occupational stress as well as GSE were measured. General linear regression analysis was performed in association analyses. Results: Both experiencing and witnessing workplace violence were significantly positively correlated with the level of occupational stress but significantly negatively correlated with job satisfaction, job initiative, and GSE. General self-efficacy significantly modified relationships between both experiencing and witnessing workplace violence with occupational stress (β = 0.49 for experiencing violence; β = 0.43 for witnessing violence; p 0.05. The levels of occupational stress declined significantly with the increase of GSE, while job satisfaction increased significantly along with its increase. The effects of GSE on occupational stress and job satisfaction weakened as the frequency of violence increased. Conclusions: The findings suggest that GSE can modify effects of workplace violence on health care workers' stress and job satisfaction. Enhancing GSE in combination with stress reduction may lead to facilitating health care workers' recovery from workplace violence, and thereby improving their work-related attitudes.

  10. Hopf bifurcation in a reaction-diffusive two-species model with nonlocal delay effect and general functional response

    International Nuclear Information System (INIS)

    Han, Renji; Dai, Binxiang

    2017-01-01

    Highlights: • We model general two-dimensional reaction-diffusion with nonlocal delay. • The existence of unique positive steady state is studied. • The bilinear form for the proposed system is given. • The existence, direction of Hopf bifurcation are given by symmetry method. - Abstract: A nonlocal delayed reaction-diffusive two-species model with Dirichlet boundary condition and general functional response is investigated in this paper. Based on the Lyapunov–Schmidt reduction, the existence, bifurcation direction and stability of Hopf bifurcating periodic orbits near the positive spatially nonhomogeneous steady-state solution are obtained, where the time delay is taken as the bifurcation parameter. Moreover, the general results are applied to a diffusive Lotka–Volterra type food-limited population model with nonlocal delay effect, and it is found that diffusion and nonlocal delay can also affect the other dynamic behavior of the system by numerical experiments.

  11. Effectiveness of Motivational Interviewing in improving lipid level in patients with dyslipidemia assisted by general practitioners: Dislip-EM study protocol.

    Science.gov (United States)

    Pérula, Luis A; Bosch, Josep M; Bóveda, Julia; Campiñez, Manuel; Barragán, Nieves; Arboniés, Juan C; Prados, Jose A; Martín, Enrique; Martín, Remedios; Massons, Josep; Criado, Margarita; Ruiz, Roger; Fernández, José A; Buitrago, Francisco; Olaya, Inmaculada; Pérez, Modesto; Ruiz, Joaquin

    2011-11-05

    The non-pharmacological approach to cholesterol control in patients with hyperlipidemia is based on the promotion of a healthy diet and physical activity. Thus, to help patients change their habits, it is essential to identify the most effective approach. Many efforts have been devoted to explain changes in or adherence to specific health behaviors. Such efforts have resulted in the development of theories that have been applied in prevention campaigns, and that include brief advice and counseling services. Within this context, Motivational Interviewing has proven to be effective in changing health behaviors in specific cases. However, more robust evidence is needed on the effectiveness of Motivational Interviewing in treating chronic pathologies -such as dyslipidemia- in patients assisted by general practitioners. This article describes a protocol to assess the effectiveness of MI as compared with general practice (brief advice), with the aim of improving lipid level control in patients with dyslipidemia assisted by a general practitioner. An open, two-arm parallel, multicentre, cluster, controlled, randomized, clinical trial will be performed. A total of 48-50 general practitioners from 35 public primary care centers in Spain will be randomized and will recruit 436 patients with dyslipidemia. They will perform an intervention based either on Motivational Interviewing or on the usual brief advice. After an initial assessment, follow-ups will be performed at 2, 4, 8 and 12 months. Primary outcomes are lipid levels (total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides) and cardiovascular risk. The study will assess the degree of dietary and physical activity improvement, weight loss in overweight patients, and adherence to treatment guidelines. Motivational interview skills constitute the primary strategies GPs use to treat their patients. Having economical, simple, effective and applicable techniques is essential for primary care professionals to help

  12. Screening tests in toxicity or drug effect studies with use of centrifichem general-purpose spectrophotometeric analyzer

    International Nuclear Information System (INIS)

    Nagy, B.; Bercz, J.P.

    1986-01-01

    CentrifiChem System 400 general-purpose spectrophotometric analyzer which can process simultaneously 30 samples and reads the reactions within milliseconds was used for toxicity studies. Organic and inorganic chemicals were screened for inhibitory action of the hydrolytic activity of sarcoplasmic reticulum (SR) Ca,Mg-ATPase and that of the sacrolemmal (SL) Na,K-ATPase, or mitochondrial ATPase (M). SR and SL were prepared from rabbit muscles, Na,K-ATPase from pig kidneys, M from pig hearts. Pseudosubstrates of paranitrophenyl phosphate and 2,4-dinitrophenyl phosphate, both proven high energy phosphate substitutes for ATPase coupled ion transfer were used. The reaction rates were followed spectrophotometrically at 405 nm measuring the accumulation of yellow nitrophenolate ions. The reported calcium transfer coupling ratio to hydrolysis of 2:1 was ascertained with use of 45 Ca in case of SR. Inhibition constants (pI) on SR, SL, and M for the pseudosubstrate hydrolysis will be given for over 20 chemicals tested. The applicability of the system to general toxicity testing and to general cardio-effective drug screening will be presented

  13. The effect of multi-professional education on the recognition and outcome of patients at risk on general wards

    DEFF Research Database (Denmark)

    Fuhrmann, L.; Perner, A.; Klausen, T.W.

    2009-01-01

    The aim of this study was to evaluate the effect of multi-professional full-scale simulation-based education of staff on the mortality and staff awareness of patients at risk on general wards. DESIGN, SETTINGS AND PATIENTS: A prospective before-and-after study conducted on four general wards...... at Herlev Hospital, Denmark. In the pre-intervention period (June-July 2006) and post-intervention period (November-December 2007), all patients on the wards had vital signs measured in the evening by study personnel, who also asked nursing staff questions about patients with abnormal vital signs...

  14. Detecting treatment-subgroup interactions in clustered data with generalized linear mixed-effects model trees.

    Science.gov (United States)

    Fokkema, M; Smits, N; Zeileis, A; Hothorn, T; Kelderman, H

    2017-10-25

    Identification of subgroups of patients for whom treatment A is more effective than treatment B, and vice versa, is of key importance to the development of personalized medicine. Tree-based algorithms are helpful tools for the detection of such interactions, but none of the available algorithms allow for taking into account clustered or nested dataset structures, which are particularly common in psychological research. Therefore, we propose the generalized linear mixed-effects model tree (GLMM tree) algorithm, which allows for the detection of treatment-subgroup interactions, while accounting for the clustered structure of a dataset. The algorithm uses model-based recursive partitioning to detect treatment-subgroup interactions, and a GLMM to estimate the random-effects parameters. In a simulation study, GLMM trees show higher accuracy in recovering treatment-subgroup interactions, higher predictive accuracy, and lower type II error rates than linear-model-based recursive partitioning and mixed-effects regression trees. Also, GLMM trees show somewhat higher predictive accuracy than linear mixed-effects models with pre-specified interaction effects, on average. We illustrate the application of GLMM trees on an individual patient-level data meta-analysis on treatments for depression. We conclude that GLMM trees are a promising exploratory tool for the detection of treatment-subgroup interactions in clustered datasets.

  15. 20 CFR 345.401 - General rule.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false General rule. 345.401 Section 345.401... EMPLOYERS' CONTRIBUTIONS AND CONTRIBUTION REPORTS Benefit Charging § 345.401 General rule. Effective January... the basis of a claim for benefits to that employee's base year employer's cumulative benefit balance...

  16. Effect of electromagnetic radiations from mobile phone base stations on general health and salivary function

    OpenAIRE

    Singh, Kushpal; Nagaraj, Anup; Yousuf, Asif; Ganta, Shravani; Pareek, Sonia; Vishnani, Preeti

    2016-01-01

    Objective: Cell phones use electromagnetic, nonionizing radiations in the microwave range, which some believe may be harmful to human health. The present study aimed to determine the effect of electromagnetic radiations (EMRs) on unstimulated/stimulated salivary flow rate and other health-related problems between the general populations residing in proximity to and far away from mobile phone base stations. Materials and Methods: A total of four mobile base stations were randomly selected from...

  17. A general theory of effect size, and its consequences for defining the benchmark response (BMR) for continuous endpoints.

    Science.gov (United States)

    Slob, Wout

    2017-04-01

    A general theory on effect size for continuous data predicts a relationship between maximum response and within-group variation of biological parameters, which is empirically confirmed by results from dose-response analyses of 27 different biological parameters. The theory shows how effect sizes observed in distinct biological parameters can be compared and provides a basis for a generic definition of small, intermediate and large effects. While the theory is useful for experimental science in general, it has specific consequences for risk assessment: it solves the current debate on the appropriate metric for the Benchmark response in continuous data. The theory shows that scaling the BMR expressed as a percent change in means to the maximum response (in the way specified) automatically takes "natural variability" into account. Thus, the theory supports the underlying rationale of the BMR 1 SD. For various reasons, it is, however, recommended to use a BMR in terms of a percent change that is scaled to maximum response and/or within group variation (averaged over studies), as a single harmonized approach.

  18. [Can Topical Negative Pressure Therapy be Performed as a Cost-Effective General Surgery Procedure in the German DRG System?].

    Science.gov (United States)

    Hirche, Z; Xiong, L; Hirche, C; Willis, S

    2016-04-01

    Topical negative pressure therapy (TNPT) has been established for surgical wound therapy with different indications. Nevertheless, there is only sparse evidence regarding its therapeutic superiority or cost-effectiveness in the German DRG system (G-DRG). This study was designed to analyse the cost-effectiveness of TNPT in the G-DRG system with a focus on daily treatment costs and reimbursement in a general surgery care setting. In this retrospective study, we included 176 patients, who underwent TNPT between 2007 and 2011 for general surgery indications. Analysis of the cost-effectiveness involved 149 patients who underwent a simulation to calculate the reimbursement with or without TNPT by a virtual control group in which the TNP procedure was withdrawn for DRG calculation. This was followed by a calculation of costs for wound dressings and TNPT rent and material costs. Comparison between the "true" and the virtual group enabled calculation of the effective remaining surplus per case. Total reimbursement by included TNPT cases was 2,323 ,70.04 €. Costs for wound dressings and TNPT rent were 102,669.20 €. In 41 cases there was a cost-effectiveness (27.5%) with 607,422.03 € with TNP treatment, while the control group without TNP generated revenues of 442,015.10 €. Costs for wound dressings and TNPT rent were 47,376.68 €. In the final account we could generate a cost-effectiveness of 6759 € in 5 years per 149 patients by TNPT. In 108 cases there was no cost-effectiveness (72.5%). TNPT applied in a representative general surgery setting allows for wound therapy without a major financial burden. Based on the costs for wound dressings and TNPT rent, a primarily medically based decision when to use TNPT can be performed in a balanced product cost accounting. This study does not analyse the superiority of TNPT in wound care, so further prospective studies are required which focus on therapeutic superiority and cost-effectiveness. Georg Thieme

  19. Transport infrastructure and technology: Investment, externalities, and general equilibrium effects

    Energy Technology Data Exchange (ETDEWEB)

    Van den Bergh, Jeroen C.J.M.; Nijkamp, P. [Faculty of Economics, Free University, Amsterdam (Netherlands)

    1993-04-01

    The paper addresses the use of general equilibrium models to analyze transportation policies. After a discussion of possible approaches, a representative set of static and dynamic models is developed and investigated, which focus on the interaction between general equilibrium, transport, infrastructure and environment. It is shown that each of these allows one to deal with specific types of policy questions. More technical modelling issues are dealt with as well, e.g. returns to scale, production functions, and disaggregation. Finally, attention is devoted to freight transport in a multisectoral production setting. 5 figs., 8 refs.

  20. The Effect of Positive and Negative Perfectionism and Type D Personality on General Health of the Aged

    Directory of Open Access Journals (Sweden)

    M. Ahamadi Tahoor

    2010-10-01

    Full Text Available Introduction & Objective: Many factors such as retirement, work disability, being isolated from the society, physical illness… affect the general health of the aged , one factor among many, is the role of psychological variables. The purpose of this study has been the investigation of the effect of positive and negative perfectionism and type D personality on general health of the aged. Materials & Methods: In this descriptive-correlational study, 80 subjects (47 males and 33 females were selected through available sampling method among the aged in nursing homes in Hamadan and Malayer. Then the positive and negative perfectionism questionnaire of Terry- Short et al, that of type D personality and Goldberg and Hiller's general health questionnaire were administered to them. Results: Positive perfectionism (r=-0.30 and type D personality (r=0.32 had significant correlations with general health. Multiple regression analysis also revealed that positive perfectionism and type D could explain at least 49 percent of the variance of general health. The females’ mean was higher than that of males concerning the variables of depression-anxiety, speech inhibition and irritability and in positive perfectionism, general health and social function variables the males’ mean was higher than that of females. Conclusion: Creating optimistic attitudes and enhancing social functions, positive perfectionism may cause the mental disorder to be decreased in old age and type D personality; however, positive perfectionism makes the aged apt to physical illness and mental disorder. (Sci J Hamadan Univ Med Sci 2010;17(3: 64-69

  1. Geometric Transitions, Topological Strings, and Generalized Complex Geometry

    International Nuclear Information System (INIS)

    Chuang, Wu-yen

    2007-01-01

    Mirror symmetry is one of the most beautiful symmetries in string theory. It helps us very effectively gain insights into non-perturbative worldsheet instanton effects. It was also shown that the study of mirror symmetry for Calabi-Yau flux compactification leads us to the territory of ''Non-Kaehlerity''. In this thesis we demonstrate how to construct a new class of symplectic non-Kaehler and complex non-Kaehler string theory vacua via generalized geometric transitions. The class admits a mirror pairing by construction. From a variety of sources, including super-gravity analysis and KK reduction on SU(3) structure manifolds, we conclude that string theory connects Calabi-Yau spaces to both complex non-Kaehler and symplectic non-Kaehler manifolds and the resulting manifolds lie in generalized complex geometry. We go on to study the topological twisted models on a class of generalized complex geometry, bi-Hermitian geometry, which is the most general target space for (2, 2) world-sheet theory with non-trivial H flux turned on. We show that the usual Kaehler A and B models are generalized in a natural way. Since the gauged supergravity is the low energy effective theory for the compactifications on generalized geometries, we study the fate of flux-induced isometry gauging in N = 2 IIA and heterotic strings under non-perturbative instanton effects. Interestingly, we find we have protection mechanisms preventing the corrections to the hyper moduli spaces. Besides generalized geometries, we also discuss the possibility of new NS-NS fluxes in a new doubled formalism

  2. Geometric Transitions, Topological Strings, and Generalized Complex Geometry

    Energy Technology Data Exchange (ETDEWEB)

    Chuang, Wu-yen; /SLAC /Stanford U., Phys. Dept.

    2007-06-29

    Mirror symmetry is one of the most beautiful symmetries in string theory. It helps us very effectively gain insights into non-perturbative worldsheet instanton effects. It was also shown that the study of mirror symmetry for Calabi-Yau flux compactification leads us to the territory of ''Non-Kaehlerity''. In this thesis we demonstrate how to construct a new class of symplectic non-Kaehler and complex non-Kaehler string theory vacua via generalized geometric transitions. The class admits a mirror pairing by construction. From a variety of sources, including super-gravity analysis and KK reduction on SU(3) structure manifolds, we conclude that string theory connects Calabi-Yau spaces to both complex non-Kaehler and symplectic non-Kaehler manifolds and the resulting manifolds lie in generalized complex geometry. We go on to study the topological twisted models on a class of generalized complex geometry, bi-Hermitian geometry, which is the most general target space for (2, 2) world-sheet theory with non-trivial H flux turned on. We show that the usual Kaehler A and B models are generalized in a natural way. Since the gauged supergravity is the low energy effective theory for the compactifications on generalized geometries, we study the fate of flux-induced isometry gauging in N = 2 IIA and heterotic strings under non-perturbative instanton effects. Interestingly, we find we have protection mechanisms preventing the corrections to the hyper moduli spaces. Besides generalized geometries, we also discuss the possibility of new NS-NS fluxes in a new doubled formalism.

  3. Science in General Education

    Science.gov (United States)

    Read, Andrew F.

    2013-01-01

    General education must develop in students an appreciation of the power of science, how it works, why it is an effective knowledge generation tool, and what it can deliver. Knowing what science has discovered is desirable but less important.

  4. General Climatology 3

    Science.gov (United States)

    Hartmann, Dennis L.

    General Climatology 3 is volume 3 of the series World Survey of Climatology, which consists of 15 volumes containing review articles on a broad range of topics. General Climatology 3 contains four chapters: ‘Human Bioclimatology,’ ‘Agricultural Climatology,’ ‘City Climate,’ and ‘Technical Climatology.’ Each of these chapters will be briefly described here.‘Human Bioclimatology,’ the first chapter, was authored by E. Flach and provides a survey of the effects on the human organism of the physical conditions at the earth's surface. It contains four main sections. A section entitled ‘Light and Life’ deals with the effects of solar radiation on man and contains much interesting information on the response of the human eye and human skin to radiation at various frequencies. ‘Air and Life’ discusses the composition of air and its effect on human health and performance, including discussions of the effects of altitude, aerosols, and noxious trace gases. ‘Temperature and Life’ discusses how the body responds to temperature and how it maintains its heat budget under the variety of conditions to which it falls subject and considerable discussion is given to objective ways to characterize air conditions that give an accurate measure of their impact on the body. This discussion leads naturally into the final section, ‘Bioclimatological Evaluation Systems,’ which addresses the problem of how to classify a particular site according to its overall suitability to human habitation.

  5. General anesthetics in children: neurotoxic or neuroprotective?

    Directory of Open Access Journals (Sweden)

    Jéssica Farias Rebouças

    2017-02-01

    Full Text Available Introduction: general anesthetics are involved in neuroprotection in adults after ischemic events and cognitive impairment, thus, they also may be associated with learning disorders in children exposed to them before three years of age. Objective: Describe about the neurotoxic effects of general anesthetics in experimental animals and children. Method: This is a systematic review, performed from search in databases and on PubMed using the keywords "neurotoxicity" and "general anesthetics," and "general anesthetics," "neurotoxicity", "children", "young child "and" pediatric ". Results: The search resulted in 185 articles. Out of these, 78 met our inclusion criteria. We found that there was a significant evidence of neurotoxicity induced by general anesthetics in experimental animals that were just born, resulting in late and permanent cognitive deficits. This effect was associated with multiple exposures, exposure length of time and combination of drugs. However, some studies found cognitive impairment after a single exposure to anesthetic. Conclusion: There is insufficient evidence to state that general anesthetics are neurotoxic and have the potential to trigger learning and behavior disabilities in children. However, we suggest caution in indicating surgery in children under three years old, analyzing risk-benefit and inserting the family in the decision process.   Keywords: Neurotoxicity; Neuroprotection; Cognitive Impairment; Children; General Anesthesics

  6. A Class of Generalized Gough-Stewart Platforms Used for Effectively Obtaining Dynamic Isotropy – An Analytical Study

    Directory of Open Access Journals (Sweden)

    Afzali-Far Behrouz

    2015-01-01

    Full Text Available In this paper, we propose a class of Generalized Gough-Stewart Platforms (GGSPs used, as a novel approach, to eliminate the classical isotropic constraint of GSPs (hexapods. GGSPs are based on the standard GSP architecture with additional rotations of the three strut-pairs. Despite the architectural generalization introduced in GGSPs, they do not require much more effort in order to be fabricated. This is due to the fact that all the struts (actuators can be chosen identical, similar to standard GSPs. We analytically show how effectively the classical isotropic constraint is removed and that still sufficient simplicity is retained. Furthermore, this paper gives an intuitive understanding of dynamic isotropy in GGSPs as well as GSPs.

  7. The most general form of deformation of the Heisenberg algebra from the generalized uncertainty principle

    Energy Technology Data Exchange (ETDEWEB)

    Masood, Syed [Department of Physics, International Islamic University, H-10 Sector, Islamabad (Pakistan); Faizal, Mir, E-mail: mirfaizalmir@gmail.com [Irving K. Barber School of Arts and Sciences, University of British Columbia – Okanagan, Kelowna, BC V1V 1V7 (Canada); Department of Physics and Astronomy, University of Lethbridge, Lethbridge, AB T1K 3M4 (Canada); Zaz, Zaid [Department of Electronics and Communication Engineering, University of Kashmir, Srinagar, Kashmir, 190006 (India); Ali, Ahmed Farag [Department of Physics, Faculty of Science, Benha University, Benha, 13518 (Egypt); Raza, Jamil [Department of Physics, International Islamic University, H-10 Sector, Islamabad (Pakistan); Shah, Mushtaq B. [Department of Physics, National Institute of Technology, Srinagar, Kashmir, 190006 (India)

    2016-12-10

    In this paper, we will propose the most general form of the deformation of Heisenberg algebra motivated by the generalized uncertainty principle. This deformation of the Heisenberg algebra will deform all quantum mechanical systems. The form of the generalized uncertainty principle used to motivate these results will be motivated by the space fractional quantum mechanics, and non-locality in quantum mechanical systems. We also analyse a specific limit of this generalized deformation for one dimensional system, and in that limit, a nonlocal deformation of the momentum operator generates a local deformation of all one dimensional quantum mechanical systems. We analyse the low energy effects of this deformation on a harmonic oscillator, Landau levels, Lamb shift, and potential barrier. We also demonstrate that this deformation leads to a discretization of space.

  8. The most general form of deformation of the Heisenberg algebra from the generalized uncertainty principle

    International Nuclear Information System (INIS)

    Masood, Syed; Faizal, Mir; Zaz, Zaid; Ali, Ahmed Farag; Raza, Jamil; Shah, Mushtaq B.

    2016-01-01

    In this paper, we will propose the most general form of the deformation of Heisenberg algebra motivated by the generalized uncertainty principle. This deformation of the Heisenberg algebra will deform all quantum mechanical systems. The form of the generalized uncertainty principle used to motivate these results will be motivated by the space fractional quantum mechanics, and non-locality in quantum mechanical systems. We also analyse a specific limit of this generalized deformation for one dimensional system, and in that limit, a nonlocal deformation of the momentum operator generates a local deformation of all one dimensional quantum mechanical systems. We analyse the low energy effects of this deformation on a harmonic oscillator, Landau levels, Lamb shift, and potential barrier. We also demonstrate that this deformation leads to a discretization of space.

  9. The effect of alcohol binge drinking in early pregnancy on general intelligence in children

    DEFF Research Database (Denmark)

    Kesmodel, Ulrik S.; Eriksen, H-L Falgreen; Underbjerg, Mette

    2012-01-01

    Please cite this paper as: Kesmodel U, Falgreen Eriksen H, Underbjerg M, Kilburn T, Støvring H, Wimberley T, Mortensen E. The effect of alcohol binge drinking in early pregnancy on general intelligence in children. BJOG 2012;119:1222-1231. Objective  To examine the effects of binge alcohol...... sampled from the Danish National Birth Cohort. Methods  Participants were sampled on the basis of maternal alcohol consumption during pregnancy. At 5 years of age the children were tested with six subtests from the Wechsler Preschool and Primary Scale of Intelligence - Revised (WPPSI-R). Parental...... education, maternal IQ, prenatal maternal smoking, the child's age at testing, the gender of the child, and tester were considered core confounding factors, whereas the full model also controlled for prenatal maternal average alcohol intake, maternal age, maternal pre-pregnancy body mass index (BMI), parity...

  10. Effectiveness of social work intervention with a systematic approach to improve general health in opioid addicts in addiction treatment centers

    Directory of Open Access Journals (Sweden)

    Raheb G

    2016-11-01

    Full Text Available Ghoncheh Raheb,1,2 Esmat Khaleghi,1 Amir Moghanibashi-Mansourieh,1 Ali Farhoudian,2 Robab Teymouri3 1Department of Social Work, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; 2Substance Abuse and Dependence Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; 3Pediatric Neurorehabilitation Research Center, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran Purpose: This study takes a systematic approach to investigate the effect of social work intervention aimed at increasing general health among opioid addicts in addiction treatment centers. Patients and methods: This is an experimental plan (pretest to posttest with a control group; the study sample included 60 patients with drug dependencies undergoing treatment in addiction treatment centers. These patients were randomly assigned as case (30 and control (30 groups. The case group was subjected to intervention over ten sessions, whereas the control group received no intervention. Both groups then passed through a posttest, while a follow-up was conducted after 4 months. Data were obtained via a General Health Questionnaire. Results: A covariance analysis test and independent and dependent t-test results indicated that a social work intervention adopting systematic approach was effective in increasing the general health of drug-addicted patients under treatment. Conclusion: Thus, the nature of the presence of social workers in addiction treatment centers has been effective and can have a significant influence by reducing anxiety and insomnia and somatic symptoms, improving patients’ self-understanding and self-recognition, and enhancing social functioning. Keywords: social work, intervention, systematic approach, general health, opioid addicts

  11. Does self-employment really raise job satisfaction? Adaptation and anticipation effects on self-employment and general job changes

    OpenAIRE

    Hanglberger, Dominik; Merz, Joachim

    2015-01-01

    Empirical analyses using cross-sectional and panel data found significantly higher levels of job satisfaction for the self-employed than for employees. We argue that by neglecting anticipation and adaptation effects estimates in previous studies might be misleading. To test this, we specify models accounting for anticipation and adaptation to self-employment and general job changes. In contrast to recent literature we find no specific long-term effect of self-employment on job satisfaction. A...

  12. The Effect of Magnetic Field and Initial Stress on Fractional Order Generalized Thermoelastic Half-Space

    Directory of Open Access Journals (Sweden)

    Sunita Deswal

    2013-01-01

    Full Text Available The aim of this paper is to study magneto-thermoelastic interactions in an initially stressed isotropic homogeneous half-space in the context of fractional order theory of generalized thermoelasticity. State space formulation with the Laplace transform technique is used to obtain the general solution, and the resulting formulation is applied to the ramp type increase in thermal load and zero stress. Solutions of the problem in the physical domain are obtained by using a numerical method of the Laplace inverse transform based on the Fourier expansion technique, and the expressions for the displacement, temperature, and stress inside the half-space are obtained. Numerical computations are carried out for a particular material for illustrating the results. Results obtained for the field variables are displayed graphically. Some comparisons have been shown in figures to present the effect of fractional parameter, ramp parameter, magnetic field, and initial stress on the field variables. Some particular cases of special interest have been deduced from the present investigation.

  13. Effective and efficient FPGA synthesis through general functional decomposition

    NARCIS (Netherlands)

    Jozwiak, L.; Slusarczyk, A.S.; Chojnacki, A.

    2003-01-01

    In this paper, a new information-driven circuit synthesis method is discussed that targets LUT-based FPGAs and FPGA-based reconfigurable system-on-a-chip platforms. The method is based on the bottom–up general functional decomposition and theory of information relationship measures that we

  14. Effect of atomic spontaneous decay on entanglement in the generalized Jaynes-Cummings model

    International Nuclear Information System (INIS)

    Hessian, H.A.; Obada, A.-S.F.; Mohamed, A.-B.A.

    2010-01-01

    Some aspects of the irreversible dynamics of a generalized Jaynes-Cummings model are addressed. By working in the dressed-state representation, it is possible to split the dynamics of the entanglement and coherence. The exact solution of the master equation in the case of a high-Q cavity with atomic decay is found. Effects of the atomic spontaneous decay on the temporal evolution of partial entropies of the atom or the field and the total entropy as a quantitative measure entanglement are elucidated. The degree of entanglement, through the sum of the negative eigenvalues of the partially transposed density matrix and the negative mutual information has been studied and compared with other measures.

  15. Pilates versus general exercise effectiveness on pain and functionality in non-specific chronic low back pain subjects.

    Science.gov (United States)

    Mostagi, Fernanda Queiroz Ribeiro Cerci; Dias, Josilainne Marcelino; Pereira, Ligia Maxwell; Obara, Karen; Mazuquin, Bruno Fles; Silva, Mariana Felipe; Silva, Monica Angelica Cardoso; de Campos, Renata Rosa; Barreto, Maria Simone Tavares; Nogueira, Jéssyca Fernandes; Lima, Tarcísio Brandão; Carregaro, Rodrigo Luiz; Cardoso, Jefferson Rosa

    2015-10-01

    Low back pain (LBP) is one of the most common causes of disability, and the Pilates method has been associated with improvements in symptoms. The purpose of this study was to assess the effectiveness of the Pilates method, when compared to general exercises, on pain and functionality after eight weeks (16 sessions, 2×/week) and a follow-up of three months, in subjects with non-specific chronic low back pain (NSCLBP). A randomised controlled trial composed of 22 subjects was proposed. Subjects were allocated into two groups: the Pilates group (PG) (n = 11) and the general exercise group (GEG) (n = 11). The PG protocol was based on the Pilates method and the GEG performed exercises to manage NSCLBP. There were no differences between the groups. When analysed over time, the GEG demonstrated improvements in functionality between baseline and the end of treatment (P = .02; Cohen'sd¯ = 0.34) and baseline and follow-up (P = .04; Cohen'sd¯ = 0.31). There were no differences between the Pilates and general exercises with regard to pain and functionality in NSCLBP subjects but general exercises were better than Pilates for increasing functionality and flexibility. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Effect of educational intervention on adoption of new endodontic technology by general dental practitioners: a questionnaire survey.

    Science.gov (United States)

    Koch, M; Eriksson, H G; Axelsson, S; Tegelberg, A

    2009-04-01

    To survey the clinical endodontic protocols of general dental practitioners (GDPs) in public dental clinics and to assess the effect of an educational intervention on the adoption of a nickel-titanium (Ni-Ti) rotary system. General dental practitioners in a Swedish Intervention County (IC), underwent an educational programme in endodontics. A follow-up questionnaire was posted to 98 GDPs in the IC and to 97 GDPs in a Control County (CC), where no specific training had been provided. The questionnaire concerned demographics, clinical endodontic protocols and instrumentation techniques. The response rate to the questionnaire was 87%. More than 90% of all GDPs reported they always or generally used rubber dam, determined working length, used the canal irrigant 0.5% buffered NaOCl and calcium hydroxide as an interappointment dressing. Two of three GDPs reported, they generally or always informed the patient of the prognosis. Every second GDP reported routines for postoperative recall and follow-up. The Ni-Ti rotary technique was reported to be completely adopted by 77% of the GDPs in the IC, significantly higher than in the CC (6%), P educational programme in Ni-Ti rotary instrumentation reported they had successfully integrated the technique into daily clinical practice.

  17. Effectiveness of Motivational Interviewing in improving lipid level in patients with dyslipidemia assisted by general practitioners: Dislip-EM study protocol

    Directory of Open Access Journals (Sweden)

    Pérula Luis A

    2011-11-01

    Full Text Available Abstract Background The non-pharmacological approach to cholesterol control in patients with hyperlipidemia is based on the promotion of a healthy diet and physical activity. Thus, to help patients change their habits, it is essential to identify the most effective approach. Many efforts have been devoted to explain changes in or adherence to specific health behaviors. Such efforts have resulted in the development of theories that have been applied in prevention campaigns, and that include brief advice and counseling services. Within this context, Motivational Interviewing has proven to be effective in changing health behaviors in specific cases. However, more robust evidence is needed on the effectiveness of Motivational Interviewing in treating chronic pathologies -such as dyslipidemia- in patients assisted by general practitioners. This article describes a protocol to assess the effectiveness of MI as compared with general practice (brief advice, with the aim of improving lipid level control in patients with dyslipidemia assisted by a general practitioner. Methods/Design An open, two-arm parallel, multicentre, cluster, controlled, randomized, clinical trial will be performed. A total of 48-50 general practitioners from 35 public primary care centers in Spain will be randomized and will recruit 436 patients with dyslipidemia. They will perform an intervention based either on Motivational Interviewing or on the usual brief advice. After an initial assessment, follow-ups will be performed at 2, 4, 8 and 12 months. Primary outcomes are lipid levels (total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and cardiovascular risk. The study will assess the degree of dietary and physical activity improvement, weight loss in overweight patients, and adherence to treatment guidelines. Discussion Motivational interview skills constitute the primary strategies GPs use to treat their patients. Having economical, simple, effective and

  18. Accreditation in general practice in Denmark

    DEFF Research Database (Denmark)

    Andersen, Merethe K; Pedersen, Line B; Siersma, Volkert

    2017-01-01

    Background: Accreditation is used increasingly in health systems worldwide. However, there is a lack of evidence on the effects of accreditation, particularly in general practice. In 2016 a mandatory accreditation scheme was initiated in Denmark, and during a 3-year period all practices, as default...... general practitioners in Denmark. Practices allocated to accreditation in 2016 serve as the intervention group, and practices allocated to accreditation in 2018 serve as controls. The selected outcomes should meet the following criteria: (1) a high degree of clinical relevance; (2) the possibility...... practice and mortality. All outcomes relate to quality indicators included in the Danish Healthcare Quality Program, which is based on general principles for accreditation. Discussion: The consequences of accreditation and standard-setting processes are generally under-researched, particularly in general...

  19. Eddy Effects in the General Circulation, Spanning Mean Currents, Mesoscale Eddies, and Topographic Generation, Including Submesoscale Nests

    Science.gov (United States)

    2014-09-30

    alongshore winds favoring upwelling circulation. As for the other EBUS (e.g., Humboldt, Benguela, and Canary Currents ), equatorward winds drive...Eddy Effects in the General Circulation, Spanning Mean Currents , Mesoscale Eddies, and Topographic Generation, Including Submesoscale Nests...environments OBJECTIVES The central scientific questions are how the eddies control the persistent currents by their eddy-induced momentum and buoyancy fluxes

  20. How trust in institutions and organizations builds general consumer confidence in the safety of food: a decomposition of effects.

    Science.gov (United States)

    de Jonge, J; van Trijp, J C M; van der Lans, I A; Renes, R J; Frewer, L J

    2008-09-01

    This paper investigates the relationship between general consumer confidence in the safety of food and consumer trust in institutions and organizations. More specifically, using a decompositional regression analysis approach, the extent to which the strength of the relationship between trust and general confidence is dependent upon a particular food chain actor (for example, food manufacturers) is assessed. In addition, the impact of specific subdimensions of trust, such as openness, on consumer confidence are analyzed, as well as interaction effects of actors and subdimensions of trust. The results confirm previous findings, which indicate that a higher level of trust is associated with a higher level of confidence. However, the results from the current study extend on previous findings by disentangling the effects that determine the strength of this relationship into specific components associated with the different actors, the different trust dimensions, and specific combinations of actors and trust dimensions. The results show that trust in food manufacturers influences general confidence more than trust in other food chain actors, and that care is the most important trust dimension. However, the contribution of a particular trust dimension in enhancing general confidence is actor-specific, suggesting that different actors should focus on different trust dimensions when the purpose is to enhance consumer confidence in food safety. Implications for the development of communication strategies that are designed to regain or maintain consumer confidence in the safety of food are discussed.

  1. Real-life effectiveness of smoking-cessation treatments in general practice clinics in Denmark. The Escape Smoke project

    DEFF Research Database (Denmark)

    Poulsen, Peter Bo; Spillemose, Heidi; Nielsen, Gerda

    2015-01-01

    BACKGROUND: The smoking prevalence has not decreased in the last years in Denmark. General practice (GP) offers smoking cessation (SC) treatment. Studies of real-life effectiveness of daily practice SC-activities from the GP-setting opposed to efficacy results from randomized clinical trials...... are few. The study aim was to evaluate the real-life effectiveness of SC-treatments for daily smokers among Danish GP-clinics. METHODS: In a multi-centre-based observational study design Danish GP-clinics with prior SC-activity recruited daily smokers motivated for quitting. As per usual clinical practice...

  2. Financial Management: DOD Needs to Clarify Its General Gift Fund Policies to Provide for Effective Oversight

    Science.gov (United States)

    2009-05-27

    Representatives Subject: Financial Management: DOD Needs to Clarify Its General Gift Fund Policies to Provide for Effective Oversight From fiscal...year 2005 through fiscal year 2008, the military services received about $295 million in monetary and nonmonetary gifts from individuals and...organizations wishing to donate gifts to the Department of Defense (DOD).1 Section 2601(a) of Title 10, U.S. Code is a long-standing authority under which

  3. The effects of single instance, multiple instance, and general case training on generalized vending machine use by moderately and severely handicapped students.

    OpenAIRE

    Sprague, J R; Horner, R H

    1984-01-01

    This report provides an experimental analysis of generalized vending machine use by six moderately or severely retarded high school students. Dependent variables were training trials to criterion and performance on 10 nontrained "generalization" vending machines. A multiple-baseline design across subjects was used to compare three strategies for teaching generalized vending machine use. Training occurred with (a) a single vending machine, (b) three similar machines, or (c) three machines that...

  4. How does processing affect storage in working memory tasks? Evidence for both domain-general and domain-specific effects.

    Science.gov (United States)

    Jarrold, Christopher; Tam, Helen; Baddeley, Alan D; Harvey, Caroline E

    2011-05-01

    Two studies that examine whether the forgetting caused by the processing demands of working memory tasks is domain-general or domain-specific are presented. In each, separate groups of adult participants were asked to carry out either verbal or nonverbal operations on exactly the same processing materials while maintaining verbal storage items. The imposition of verbal processing tended to produce greater forgetting even though verbal processing operations took no longer to complete than did nonverbal processing operations. However, nonverbal processing did cause forgetting relative to baseline control conditions, and evidence from the timing of individuals' processing responses suggests that individuals in both processing groups slowed their responses in order to "refresh" the memoranda. Taken together the data suggest that processing has a domain-general effect on working memory performance by impeding refreshment of memoranda but can also cause effects that appear domain-specific and that result from either blocking of rehearsal or interference.

  5. Longitudinal surveys on effects of changes in road traffic noise: effects on sleep assessed by general questionnaires and 3-day sleep logs

    Science.gov (United States)

    Öhrström, E.

    2004-09-01

    Adverse health effects including sleep disturbances by road traffic noise were studied among inhabitants in a residential area near Västra Bräckevägen in Göteborg city, Sweden, in 1986 and 1987, before and after the introduction of night traffic regulations. The results of those studies showed a higher prevalence of sleep disturbances and poorer sleep quality in the exposed areas as compared with the control area. This paper presents results on sleep based on new studies done with general questionnaires and daily sleep logs for a period of 3 nights in 1997 and 1999 in the same areas, before and after the opening of a new tunnel for road traffic. At this time, road traffic had been substantially reduced from about 25 000 to 2 400 vehicles per 24 h and from 1375 to 180 vehicles per night (22-06). It is concluded from these long-term investigations that exposure to high levels of road traffic noise induces adverse effects on sleep and that sleep quality is significantly improved after an extensive noise reduction. Sleep quality assessed by a single general questionnaire may give equally good precision as daily reports on sleep over several days. Furthermore, a higher response rate is achieved by a single questionnaire.

  6. The effectiveness of consultation-liaison psychiatry in the general hospital setting: a systematic review.

    Science.gov (United States)

    Wood, Rebecca; Wand, Anne P F

    2014-03-01

    The aim of this study was to review how the effectiveness of consultation liaison psychiatry (CLP) services has been measured and to evaluate the strength of the evidence for effectiveness. Systematic review of medical databases using broad search terms as well as expert opinion was sought. The literature search was restricted to studies of general, whole-of-hospital inpatient CLP services. Forty articles were found and grouped into five measurements of effectiveness: cost effectiveness including length of stay, concordance, staff and patient feedback, and follow-up outcome studies. All measurements contributed to the evaluation of CLP services, but no one measure in isolation could adequately cover the multifaceted roles of CLP. Concordance was the only measurement with an established, consistent approach for evaluation. Cost effectiveness and follow-up outcome studies were the only measures with levels of evidence above four, however the three follow-up outcome studies reported conflicting results. Subjective evidence derived from patient and staff feedback is important but presently lacking due to methodological problems. The effectiveness of CLP services was demonstrated by cost-effectiveness, earlier referrals to CLP predicting shorter length of stay, and concordance with some management recommendations. There is evidence that some CLP services are cost-effective and reduce length of stay when involved early and that referrers follow certain recommendations. However, many studies had disparate results and were methodologically flawed. Future research should focus on standardising patient and staff feedback, and short-term patient outcomes. Crown Copyright © 2014. Published by Elsevier Inc. All rights reserved.

  7. Study of the effects of ß-myrcene on rat fertility and general reproductive performance

    Directory of Open Access Journals (Sweden)

    Paumgartten F.J.R.

    1998-01-01

    Full Text Available ß-Myrcene (MYR is a monoterpene found in the oils of a variety of aromatic plants including lemongrass, verbena, hop, bay, and others. MYR and essential oils containing this terpenoid compound are used in cosmetics, household products, and as flavoring food additives. This study was undertaken to investigate the effects of MYR on fertility and general reproductive performance in the rat. MYR (0, 100, 300 and 500 mg/kg in peanut oil was given by gavage to male Wistar rats (15 per dose group for 91 days prior to mating and during the mating period, as well as to females (45 per dose group continuously for 21 days before mating, during mating and pregnancy, and throughout the period of lactation up to postnatal day 21. On day 21 of pregnancy one-third of the females of each group were submitted to cesarean section. Resorption, implantation, as well as dead and live fetuses were counted. All fetuses were examined for external malformations, weighed, and cleared and stained with Alizarin Red S for skeleton evaluation. The remaining dams were allowed to give birth to their offspring. The progeny was examined at birth and subsequently up to postnatal day 21. Mortality, weight gain and physical signs of postnatal development were evaluated. Except for an increase in liver and kidney weights, no other sign of toxicity was noted in male and female rats exposed to MYR. MYR did not affect the mating index (proportion of females impregnated by males or the pregnancy index (ratio of pregnant to sperm-positive females. No sign of maternal toxicity and no increase in externally visible malformations were observed at any dose level. Only at the highest dose tested (500 mg/kg did MYR induce an increase in the resorption rate and a higher frequency of fetal skeleton anomalies. No adverse effect of MYR on postnatal weight gain was noted but days of appearance of primary coat, incisor eruption and eye opening were slightly delayed in the exposed offspring. On the

  8. A general approach-avoidance hypothesis of oxytocin: accounting for social and non-social effects of oxytocin.

    Science.gov (United States)

    Harari-Dahan, Osnat; Bernstein, Amit

    2014-11-01

    We critically reexamine extant theory and empirical study of Oxytocin. We question whether OT is, in fact, a "social neuropeptide" as argued in dominant theories of OT. We critically review human and animal research on the social and non-social effects of Oxytocin, including behavioral, psychophysiological, neurobiological, and neuroimaging studies. We find that extant (social) theories of Oxytocin do not account for well-documented non-social effects of Oxytocin. Furthermore, we find a range of evidence that social and non-social effects of Oxytocin may be mediated by core approach-avoidance motivational processes. We propose a General Approach-avoidance Hypothesis of Oxytocin (GAAO). We argue that the GAAO may provide a parsimonious account of established social and non-social effects of Oxytocin. We thus re-conceptualize the basic function(s) and mechanism(s) of action of Oxytocin. Finally, we highlight implications of the GAAO for basic and clinical research in humans

  9. The Effect of General Corrosion on the Guided Wave Inspection of the Pipeline

    Directory of Open Access Journals (Sweden)

    Zhang Jin Heng

    2016-01-01

    Full Text Available The guided wave method can inspect pipelines very quickly and widely. For instance, it can inspect the overall pipelines by digging several detection pits or removing part of coating material to set the array ring. However, it will make the guided wave attenuate more seriously and make the signals hard to identify when setting the array ring on the general corrosion. In this study, the wave propagation will be discussed when the general corrosion is under the array ring and the severe localized corrosion is inside the general corrosion via experiment and finite element method. The results showed that the excitation energy will be lower when the array ring set on the pipe surface with the general corrosion. By two-dimensional Fourier transform analysis, its non-uniform contact surface will increase asymmetric modal and mix signals. The energy attenuation will increase when the corrosion depth is deepened or the inspection frequency is risen. For example, the 2 mm deep general corrosion will attenuate −1.09 dB/m at 20 kHz and attenuate −3.01 dB/m at 40 kHz; the 4 mm deep general corrosion will attenuation −5.76 dB/m at 20 kHz and attenuation −23.19 dB/m at 40 kHz. However, the coherent signals which were caused by the general corrosion will decay with increasing frequency. For example, the coherent signals of 2 mm deep general corrosion are −23.67 dB at 20 kHz and −35.44 dB at 40 kHz; then, the 20 mm long and 3.5 mm deep localized corrosion which signal is −26.34 dB at 20 kHz and −26.94 dB at 40 kHz will be detected easily at high frequency. It can provide detectors to understand the impact when the array ring set on the area of general corrosion and the way to distinguish the localized corrosion which is inside the area of general corrosion.

  10. Generalized Galilean algebras and Newtonian gravity

    Science.gov (United States)

    González, N.; Rubio, G.; Salgado, P.; Salgado, S.

    2016-04-01

    The non-relativistic versions of the generalized Poincaré algebras and generalized AdS-Lorentz algebras are obtained. These non-relativistic algebras are called, generalized Galilean algebras of type I and type II and denoted by GBn and GLn respectively. Using a generalized Inönü-Wigner contraction procedure we find that the generalized Galilean algebras of type I can be obtained from the generalized Galilean algebras type II. The S-expansion procedure allows us to find the GB5 algebra from the Newton Hooke algebra with central extension. The procedure developed in Ref. [1] allows us to show that the nonrelativistic limit of the five dimensional Einstein-Chern-Simons gravity is given by a modified version of the Poisson equation. The modification could be compatible with the effects of Dark Matter, which leads us to think that Dark Matter can be interpreted as a non-relativistic limit of Dark Energy.

  11. Generalized epilepsy syndromes and callosal thickness: Differential effects between patients with juvenile myoclonic epilepsy and those with generalized tonic-clonic seizures alone.

    Science.gov (United States)

    Anastasopoulou, Stavroula; Kurth, Florian; Luders, Eileen; Savic, Ivanka

    2017-01-01

    The definition of two well-studied genetic generalized epilepsy syndromes (GGE) - juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic-clonic seizures alone (GTCS) - suggests the absence of structural cerebral abnormalities. Nevertheless, there are various reports of such abnormalities (especially in JME), where effects mainly occur within thalamus and mesial prefrontal regions. This raises the question of whether JME is particularly linked to midline structure abnormalities, which may also involve the corpus callosum. We studied callosal morphology in a well-matched sample of 22 JME patients, 15 GTCS patients, and 42 controls (CTL) for all of whom we obtained T1-weighted data on a 3T MRI scanner. More specifically, we measured callosal thickness at 100 equidistant points across the callosal surface, and subsequently compared the three groups (JME, GTCS, and CTL) against each other. Significant differences between JME patients and controls were observed within the callosal genu, anterior midbody, and isthmus, with thinner regions in JME patients. There were no significant differences between GTCS patients and controls, and also not between JME patients and GTCS patients. The present outcomes point to callosal abnormalities in JME patients suggesting an impairment of interhemisperic communication between prefrontal, motor, parietal and temporal cortices. These findings further support the notion that structural aberrations are present and differentiated across GGE syndromes, with significant callosal deviations from normality in JME. Copyright © 2016 Elsevier B.V. All rights reserved.

  12. Effects of general, specific and combined warm-up on explosive muscular performance

    Directory of Open Access Journals (Sweden)

    David Cristobal Andrade

    2015-02-01

    Full Text Available The purpose of this study was to compare the acute effects of general, specific and combined warm-up (WU on explosive performance. Healthy male (n=10 subjects participated in six WU protocols in a crossover randomized study design. Protocols were: passive rest (PR; 15 min of passive rest, running (Run; 5 min of running at 70% of maximum heart rate, stretching (STR; 5 min of static stretching exercise, jumping [Jump; 5 min of jumping exercises – 3x8 countermovement jumps (CMJ and 3x8 drop jumps from 60 cm (DJ60], and combined (COM; protocols Run + STR + Jump combined. Immediately before and after each WU, subjects were assessed for explosive concentric-only (i.e. squat jump – SJ, slow stretch-shortening cycle (i.e. CMJ, fast stretch-shortening cycle (i.e. DJ60 and contact time (CT muscle performance. PR significantly reduced SJ performance (p =0.007. Run increased SJ (p =0.0001 and CMJ (p =0.002. STR increased CMJ (p =0.048. Specific WU (i.e. Jump increased SJ (p =0.001, CMJ (p =0.028 and DJ60 (p =0.006 performance. COM increased CMJ performance (p =0.006. Jump was superior in SJ performance vs. PR (p =0.001. Jump reduced (p =0.03 CT in DJ60. In conclusion, general, specific and combined WU increase slow stretch-shortening cycle (SSC muscle performance, but only specific WU increases fast SSC muscle performance. Therefore, to increase fast SSC performance, specific fast SSC muscle actions must be included during the WU.

  13. The effect of advertising in clinical software on general practitioners' prescribing behaviour.

    Science.gov (United States)

    Henderson, Joan; Miller, Graeme; Pan, Ying; Britt, Helena

    2008-01-07

    To assess the effect of pharmaceutical advertising embedded in clinical software on the prescribing behaviour of general practitioners. Secondary analysis of data from a random sample of 1336 Australian GPs who participated in Bettering the Evaluation and Care of Health, a national continuous cross-sectional survey of general practice activity, between November 2003 and March 2005. The prescribing behaviour of participants who used the advertising software was compared with that of participants who did not, for seven pharmaceutical products advertised continually throughout the study period. Prescription for advertised product as a proportion (%) of prescriptions for all pharmaceutical products in the same generic class or group. GP age, practice location, accreditation status, patient bulk-billing status and hours worked were significantly associated (P advertising software. We found no significant differences, either before or after adjustment for these confounders, in the prescribing rate of Lipitor (adjusted odds ratio [AOR], 0.90; P = 0.26); Micardis (AOR, 0.98; P = 0.91); Mobic (AOR, 1.02; P = 0.89); Norvasc (AOR, 1.02; P = 0.91); Natrilix (AOR, 0.80; P = 0.32); or Zanidip (AOR, 0.88; P = 0.47). GPs using advertising software prescribed Nexium significantly less often than those not using advertising software (AOR, 0.78; P = 0.02). When all advertised products were combined and compared with products that were not advertised, no difference in the overall prescribing behaviour was demonstrated (AOR, 0.96; P = 0.42). Exposure to advertisements in clinical software has little influence on the prescribing behaviour of GPs.

  14. Effectiveness of flumazenil on return of cognitive functions after a general anesthetic.

    Science.gov (United States)

    Pregler, J L; Mok, M S; Steen, S N

    1994-09-01

    Benzodiazepines used intra-operatively can occasionally cause prolonged sedation. Flumazenil (Romazicon) is an imidazobenzodiazepine that functions as a benzodiazepine receptor antagonist. This clinical investigation was designed to evaluate the efficacy and of intravenous flumazenil in reversing the central effects of midazolam after a general anesthetic using midazolam for maintenance. 30 ASA I-III inpatients entered and completed this study. All were interviewed preoperatively and baseline performance on a battery of psychomotor tests was obtained. Parameters measured included an assessment of sleep status, vital signs, responsiveness to verbal stimuli, quality of speech, facial expression, eye coordination, recognition of a picture card, finger-finger-to-nose (FFN) coordination and overall discharge readiness. General anesthesia was induced with midazolam. Midazolam and fentanyl were the primary maintenance agents combined with N2O and O2 (70:30) and a limited concentration of isoflurane. In the recovery room the test drug was administered in a double-blinded, randomized manner. 20 patients received flumazenil (F), the rest placebo (P). Testing was done at times 0, 5, 15, 30, 60, 120, and 180 min in the PACU. Memory testing consisted of recall of study pictures at 180 min and recognition on the first postoperative day. Demographic data were similar for both groups with the exception of age. The F group had a higher mean composite score (comprising responsiveness to verbal stimuli, speech, facial expression and eye coordination) and better FFN scores at 5, 15, and 30 min (p pictures better at 5 and 15 min (p WORDS)

  15. The Confrontation between General Relativity and Experiment

    Directory of Open Access Journals (Sweden)

    Will Clifford M.

    2006-03-01

    Full Text Available The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed. Einstein’s equivalence principle (EEP is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and other binary pulsar systems have yielded other tests, especially of strong-field effects. When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.

  16. Generalized spin-dependent WIMP-nucleus interactions and the DAMA modulation effect

    Energy Technology Data Exchange (ETDEWEB)

    Scopel, Stefano; Yoon, Kook-Hyun; Yoon, Jong-Hyun, E-mail: scopel@sogang.ac.kr, E-mail: koreasds@naver.com, E-mail: pledge200@gmail.com [Department of Physics, Sogang University, Seoul (Korea, Republic of)

    2015-07-01

    Guided by non-relativistic Effective Field Theory (EFT) we classify the most general spin-dependent interactions between a fermionic Weakly Interacting Massive Particle (WIMP) and nuclei, and within this class of models we discuss the viability of an interpretation of the DAMA modulation result in terms of a signal from WIMP elastic scatterings using a halo-independent approach. We find that, although several relativistic EFT's can lead to a spin-dependent cross section, in some cases with an explicit, non-negligible dependence on the WIMP incoming velocity, three main scenarios can be singled out in the non-relativistic limit which approximately encompass them all, and that only differ by their dependence on the transferred momentum. For two of them compatibility between DAMA and other constraints is possible for a WIMP mass below 30 GeV, but only for a WIMP velocity distribution in the halo of our Galaxy which departs from a Maxwellian. This is achieved by combining a suppression of the WIMP effective coupling to neutrons (to evade constraints from xenon and germanium detectors) to an explicit quadratic or quartic dependence of the cross section on the transferred momentum (that leads to a relative enhancement of the expected rate off sodium in DAMA compared to that off fluorine in droplet detectors and bubble chambers). For larger WIMP masses the same scenarios are excluded by scatterings off iodine in COUPP.

  17. Magnetism and rotation effect on surface waves in fibre-reinforced anisotropic general viscoelastic media of higher order

    Energy Technology Data Exchange (ETDEWEB)

    Abo-Dahab, S. M. [Taif University, Taif (Saudi Arabia); Abd-Alla, A. M. [SVU, Qena (Egypt); Khan, Aftab [Sohag University, Sohag (Egypt)

    2015-08-15

    The aim of this paper is to study the propagation of surface waves in a rotating fibre-reinforced viscoelastic media of higher order under the influence of magnetic field. The general surface wave speeds derived to study the effects of rotation and magnetic field on surface waves. Particular cases for Stoneley, Love and Rayleigh waves are also discussed and dispersion relation for the waves has been deduced. The results obtained in this investigation are more general in the sense that some earlier published results are obtained from our result as special cases. For order zero our results are well agreement to fibre-reinforced materials. Also by neglecting the reinforced elastic parameters, the results reduce to well known isotropic medium. It is observed that in a rotating medium the surface waves are dispersive. Also magnetic effects play a significant roll. It is observed that Love wave remain unaffected in a rotating medium but remain under the influence of magnetic field. Rayleigh waves are affected by rotation and magnetic field whereas Stoneley waves are independent of Maxwell stresses. It is also observed that, surface waves cannot propagate in a fast rotating medium or in the presence of magnetic field of high intensity. Numerical results for particular materials are given and illustrated graphically. The results indicate that the effect of rotation and magnetic field are very pronounced.

  18. Magnetism and rotation effect on surface waves in fibre-reinforced anisotropic general viscoelastic media of higher order

    International Nuclear Information System (INIS)

    Abo-Dahab, S. M.; Abd-Alla, A. M.; Khan, Aftab

    2015-01-01

    The aim of this paper is to study the propagation of surface waves in a rotating fibre-reinforced viscoelastic media of higher order under the influence of magnetic field. The general surface wave speeds derived to study the effects of rotation and magnetic field on surface waves. Particular cases for Stoneley, Love and Rayleigh waves are also discussed and dispersion relation for the waves has been deduced. The results obtained in this investigation are more general in the sense that some earlier published results are obtained from our result as special cases. For order zero our results are well agreement to fibre-reinforced materials. Also by neglecting the reinforced elastic parameters, the results reduce to well known isotropic medium. It is observed that in a rotating medium the surface waves are dispersive. Also magnetic effects play a significant roll. It is observed that Love wave remain unaffected in a rotating medium but remain under the influence of magnetic field. Rayleigh waves are affected by rotation and magnetic field whereas Stoneley waves are independent of Maxwell stresses. It is also observed that, surface waves cannot propagate in a fast rotating medium or in the presence of magnetic field of high intensity. Numerical results for particular materials are given and illustrated graphically. The results indicate that the effect of rotation and magnetic field are very pronounced.

  19. The effects of cognitive load on attention control in subclinical anxiety and Generalized Anxiety Disorder

    Science.gov (United States)

    Najmi, Sadia; Amir, Nader; Frosio, Kristen E.; Ayers, Catherine

    2014-01-01

    Poor regulation of emotions may involve impaired attention control. In the current paper, we report the results of two studies examining the interaction of anxiety, attention control, and cognitive load. In Study I, using a performance-based task to assess attention control, we examined whether anxiety is associated with impaired attention control, and whether these effects are influenced by working memory load. In Study II we examined these effects in patients with a diagnosis of Generalized Anxiety Disorder (GAD) compared to non-anxious control (NAC) participants. Results of Study I showed that high anxiety was associated with increased attention control, that is decreased interference from distractors, but only under high cognitive load. These results were replicated in Study II such that individuals with GAD showed increased attention control relative to NACs, but only under high cognitive load. These results help clarify previous predictions regarding the effect of anxiety on attention control. PMID:25355423

  20. Noradrenergic Stimulation Impairs Memory Generalization in Women.

    Science.gov (United States)

    Kluen, Lisa Marieke; Agorastos, Agorastos; Wiedemann, Klaus; Schwabe, Lars

    2017-07-01

    Memory generalization is essential for adaptive decision-making and action. Our ability to generalize across past experiences relies on medial-temporal lobe structures, known to be highly sensitive to stress. Recent evidence suggests that stressful events may indeed interfere with memory generalization. Yet, the mechanisms involved in this generalization impairment are unknown. We tested here whether a pharmacological elevation of major stress mediators-noradrenaline and glucocorticoids-is sufficient to disrupt memory generalization. In a double-blind, placebo-controlled design, healthy men and women received orally a placebo, hydrocortisone, the α2-adrenoceptor antagonist yohimbine that leads to increased noradrenergic stimulation, or both drugs, before they completed an associative learning task probing memory generalization. Drugs left learning performance intact. Yohimbine, however, led to a striking generalization impairment in women, but not in men. Hydrocortisone, in turn, had no effect on memory generalization, neither in men nor in women. The present findings indicate that increased noradrenergic activity, but not cortisol, is sufficient to disrupt memory generalization in a sex-specific manner, with relevant implications for stress-related mental disorders characterized by generalization deficits.

  1. The Effects of Life Domains, Constraints, and Motivations on Academic Dishonesty: A Partial Test and Extension of Agnew's General Theory.

    Science.gov (United States)

    Cochran, John K

    2017-08-01

    Recently, Robert Agnew introduced a new general theory of crime and delinquency in which he attempted to corral the vast array of theoretical "causes" of criminal conduct into a more parsimonious statement organized into one of five life domains: self, family, peers, school, and work as well as constraints against crime and motivation for it. These domains are depicted as the source of constraints and motivations and whose effects are, in part, mediated by these constraints and motivations. Based on self-report data on academic dishonesty from a sample of college students, the present study attempts to test this general theory. While several of the life domain variables had significant effects of cheating in the baseline model, all of these effects were fully mediated by constraints and motivations. In the final model, academic dishonesty was observed to be most significantly affected by the perceived severity of formal sanction threats, the number of credit hours enrolled, the frequency of skipping classes, and pressure from friends.

  2. Gender and General Strain Theory: A Comparison of Strains, Mediating, and Moderating Effects Explaining Three Types of Delinquency

    Science.gov (United States)

    Moon, Byongook; Morash, Merry

    2017-01-01

    The present study of 659 Korean adolescents tests General Strain Theory's (GST) utility in explaining gender differences in delinquency causation. It models the effects of key strains, negative emotions, and a composite measure of several conditioning factors separately for boys and girls and for delinquency. Consistent with the theory, males and…

  3. Generalized linear longitudinal mixed models with linear covariance structure and multiplicative random effects

    DEFF Research Database (Denmark)

    Holst, René; Jørgensen, Bent

    2015-01-01

    The paper proposes a versatile class of multiplicative generalized linear longitudinal mixed models (GLLMM) with additive dispersion components, based on explicit modelling of the covariance structure. The class incorporates a longitudinal structure into the random effects models and retains...... a marginal as well as a conditional interpretation. The estimation procedure is based on a computationally efficient quasi-score method for the regression parameters combined with a REML-like bias-corrected Pearson estimating function for the dispersion and correlation parameters. This avoids...... the multidimensional integral of the conventional GLMM likelihood and allows an extension of the robust empirical sandwich estimator for use with both association and regression parameters. The method is applied to a set of otholit data, used for age determination of fish....

  4. Generalized heat-transport equations: parabolic and hyperbolic models

    Science.gov (United States)

    Rogolino, Patrizia; Kovács, Robert; Ván, Peter; Cimmelli, Vito Antonio

    2018-03-01

    We derive two different generalized heat-transport equations: the most general one, of the first order in time and second order in space, encompasses some well-known heat equations and describes the hyperbolic regime in the absence of nonlocal effects. Another, less general, of the second order in time and fourth order in space, is able to describe hyperbolic heat conduction also in the presence of nonlocal effects. We investigate the thermodynamic compatibility of both models by applying some generalizations of the classical Liu and Coleman-Noll procedures. In both cases, constitutive equations for the entropy and for the entropy flux are obtained. For the second model, we consider a heat-transport equation which includes nonlocal terms and study the resulting set of balance laws, proving that the corresponding thermal perturbations propagate with finite speed.

  5. General general game AI

    OpenAIRE

    Togelius, Julian; Yannakakis, Georgios N.; 2016 IEEE Conference on Computational Intelligence and Games (CIG)

    2016-01-01

    Arguably the grand goal of artificial intelligence research is to produce machines with general intelligence: the capacity to solve multiple problems, not just one. Artificial intelligence (AI) has investigated the general intelligence capacity of machines within the domain of games more than any other domain given the ideal properties of games for that purpose: controlled yet interesting and computationally hard problems. This line of research, however, has so far focuse...

  6. Generalized cost-effectiveness analysis for national-level priority-setting in the health sector

    Directory of Open Access Journals (Sweden)

    Edejer Tessa

    2003-12-01

    Full Text Available Abstract Cost-effectiveness analysis (CEA is potentially an important aid to public health decision-making but, with some notable exceptions, its use and impact at the level of individual countries is limited. A number of potential reasons may account for this, among them technical shortcomings associated with the generation of current economic evidence, political expediency, social preferences and systemic barriers to implementation. As a form of sectoral CEA, Generalized CEA sets out to overcome a number of these barriers to the appropriate use of cost-effectiveness information at the regional and country level. Its application via WHO-CHOICE provides a new economic evidence base, as well as underlying methodological developments, concerning the cost-effectiveness of a range of health interventions for leading causes of, and risk factors for, disease. The estimated sub-regional costs and effects of different interventions provided by WHO-CHOICE can readily be tailored to the specific context of individual countries, for example by adjustment to the quantity and unit prices of intervention inputs (costs or the coverage, efficacy and adherence rates of interventions (effectiveness. The potential usefulness of this information for health policy and planning is in assessing if current intervention strategies represent an efficient use of scarce resources, and which of the potential additional interventions that are not yet implemented, or not implemented fully, should be given priority on the grounds of cost-effectiveness. Health policy-makers and programme managers can use results from WHO-CHOICE as a valuable input into the planning and prioritization of services at national level, as well as a starting point for additional analyses of the trade-off between the efficiency of interventions in producing health and their impact on other key outcomes such as reducing inequalities and improving the health of the poor.

  7. A Longitudinal Analysis of the Effects of Socioeconomic Factors, Foreign Media, and Attitude toward Appearance on General and Central Adiposity in Chinese Adolescents.

    Science.gov (United States)

    Felicitas, Jamie Q; Tanenbaum, Hilary C; Li, Yawen; Chou, Chih-Ping; Palmer, Paula H; Spruijt-Metz, Donna; Reynolds, Kim D; Johnson, C Anderson; Xie, Bin

    This paper explores the longitudinal effects of socioeconomic factors (i.e., parent education and family income level), foreign media, and attitude toward appearance on general and central adiposity among Chinese adolescents. A longitudinal analysis was performed using data from the China Seven Cities Study, a health promotion and smoking prevention study conducted in seven cities across Mainland China between 2002 and 2005. Participants included 5,020 middle and high school students and their parents. Explanatory variables included foreign media exposure, attitude toward appearance, parent education, and family income. Three-level, random-effect models were used to predict general adiposity (i.e., body mass index) and central adiposity (i.e., waist circumference). The Generalized Estimating Equation approach was utilized to determine the effect of explanatory variables on overweight status. Among girls, foreign media exposure was significantly negatively associated with general adiposity over time (β=-0.06, p=0.01 for middle school girls; β=-0.06, p=0.03 for high school girls). Attitude toward appearance was associated with lesser odds of being overweight, particularly among high school girls (OR=0.86, pgrade levels, family income was significantly negatively associated with central adiposity over time. Interventions addressing Chinese adolescent overweight/obesity should consider these factors as potential focus areas.

  8. General equilibrium effects of a supply side GHG mitigation option under the Clean Development Mechanism.

    Science.gov (United States)

    Timilsina, Govinda R; Shrestha, Ram M

    2006-09-01

    The Clean Development Mechanism (CDM) under the Kyoto Protocol to the United Nations Framework Convention on Climate Change is considered a key instrument to encourage developing countries' participation in the mitigation of global climate change. Reduction of greenhouse gas (GHG) emissions through the energy supply and demand side activities are the main options to be implemented under the CDM. This paper analyses the general equilibrium effects of a supply side GHG mitigation option-the substitution of thermal power with hydropower--in Thailand under the CDM. A static multi-sector general equilibrium model has been developed for the purpose of this study. The key finding of the study is that the substitution of electricity generation from thermal power plants with that from hydropower plants would increase economic welfare in Thailand. The supply side option would, however, adversely affect the gross domestic product (GDP) and the trade balance. The percentage changes in economic welfare, GDP and trade balance increase with the level of substitution and the price of certified emission reduction (CER) units.

  9. Testing general relativity on accelerators

    Directory of Open Access Journals (Sweden)

    Tigran Kalaydzhyan

    2015-11-01

    Full Text Available Within the general theory of relativity, the curvature of spacetime is related to the energy and momentum of the present matter and radiation. One of the more specific predictions of general relativity is the deflection of light and particle trajectories in the gravitational field of massive objects. Bending angles for electromagnetic waves and light in particular were measured with a high precision. However, the effect of gravity on relativistic massive particles was never studied experimentally. Here we propose and analyze experiments devoted to that purpose. We demonstrate a high sensitivity of the laser Compton scattering at high energy accelerators to the effects of gravity. The main observable – maximal energy of the scattered photons – would experience a significant shift in the ambient gravitational field even for otherwise negligible violation of the equivalence principle. We confirm predictions of general relativity for ultrarelativistic electrons of energy of tens of GeV at a current level of resolution and expect our work to be a starting point of further high-precision studies on current and future accelerators, such as PETRA, European XFEL and ILC.

  10. Generalized zero point anomaly

    International Nuclear Information System (INIS)

    Nogueira, Jose Alexandre; Maia Junior, Adolfo

    1994-01-01

    It is defined Zero point Anomaly (ZPA) as the difference between the Effective Potential (EP) and the Zero point Energy (ZPE). It is shown, for a massive and interacting scalar field that, in very general conditions, the renormalized ZPA vanishes and then the renormalized EP and ZPE coincide. (author). 3 refs

  11. General relativistic effects in the structure of massive white dwarfs

    Science.gov (United States)

    Carvalho, G. A.; Marinho, R. M.; Malheiro, M.

    2018-04-01

    In this work we investigate the structure of white dwarfs using the Tolman-Oppenheimer-Volkoff equations and compare our results with those obtained from Newtonian equations of gravitation in order to put in evidence the importance of general relativity (GR) for the structure of such stars. We consider in this work for the matter inside white dwarfs two equations of state, frequently found in the literature, namely, the Chandrasekhar and Salpeter equations of state. We find that using Newtonian equilibrium equations, the radii of massive white dwarfs (M>1.3M_{⊙ }) are overestimated in comparison with GR outcomes. For a mass of 1.415M_{⊙ } the white dwarf radius predicted by GR is about 33% smaller than the Newtonian one. Hence, in this case, for the surface gravity the difference between the general relativistic and Newtonian outcomes is about 65%. We depict the general relativistic mass-radius diagrams as M/M_{⊙ }=R/(a+bR+cR^2+dR^3+kR^4), where a, b, c and d are parameters obtained from a fitting procedure of the numerical results and k=(2.08× 10^{-6}R_{⊙ })^{-1}, being R_{⊙ } the radius of the Sun in km. Lastly, we point out that GR plays an important role to determine any physical quantity that depends, simultaneously, on the mass and radius of massive white dwarfs.

  12. Generalized functions

    CERN Document Server

    Gelfand, I M; Graev, M I; Vilenkin, N Y; Pyatetskii-Shapiro, I I

    Volume 1 is devoted to basics of the theory of generalized functions. The first chapter contains main definitions and most important properties of generalized functions as functional on the space of smooth functions with compact support. The second chapter talks about the Fourier transform of generalized functions. In Chapter 3, definitions and properties of some important classes of generalized functions are discussed; in particular, generalized functions supported on submanifolds of lower dimension, generalized functions associated with quadratic forms, and homogeneous generalized functions are studied in detail. Many simple basic examples make this book an excellent place for a novice to get acquainted with the theory of generalized functions. A long appendix presents basics of generalized functions of complex variables.

  13. Effects of health education for migrant females with psychosomatic complaints treated by general practitioners. A randomised controlled evaluation study

    NARCIS (Netherlands)

    Kocken, P.L.; Zwanenburg, E.J.-v.; Hoop, T.de

    2008-01-01

    Objective: : The effectiveness of use of migrant health educators in the general practitioners' care for female migrants with psychosomatic problems was evaluated to contribute to the improvement of the care for these patients. Methods: : A randomised controlled trial (RCT) design was used. A total

  14. Interpersonal sensitivity mediates the effects of child abuse and affective temperaments on depressive symptoms in the general adult population

    Directory of Open Access Journals (Sweden)

    Otsuka A

    2017-10-01

    Full Text Available Ayano Otsuka,1 Yoshikazu Takaesu,1 Mitsuhiko Sato,1 Jiro Masuya,1 Masahiko Ichiki,1 Ichiro Kusumi,2 Takeshi Inoue1 1Department of Psychiatry, Tokyo Medical University, Tokyo, 2Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan Background: Recent studies have suggested that multiple factors interact with the onset and prognosis of major depressive disorders. In this study, we investigated how child abuse, affective temperaments, and interpersonal sensitivity are interrelated, and how they affect depressive symptoms in the general adult population. Subjects and methods: A total of 415 volunteers from the general adult population completed the Patient Health Questionnaire-9, the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego-Autoquestionnaire version, the Child Abuse and Trauma Scale, and the Interpersonal Sensitivity Measure, which are all self-administered questionnaires. Data were subjected to structural equation modeling (Mplus, and single and multiple regression analyses. Results: The effect of child abuse on depressive symptoms was mediated by interpersonal sensitivity and 4 affective temperaments, including depressive, cyclothymic, anxious, and irritable temperaments. In addition, the effect of these temperaments on depressive symptoms was mediated by interpersonal sensitivity, indicating the indirect enhancement of depressive symptoms. In contrast to these 4 temperaments, the hyperthymic temperament did not mediate the effect of child abuse on depressive symptoms; its effect was not mediated by interpersonal sensitivity. However, a greater hyperthymic temperament predicted decreased depressive symptoms and interpersonal sensitivity, independent of any mediation effect. Limitations: Because this is a cross-sectional study, long-term prospective studies are necessary to confirm its findings. Therefore, recall bias should be considered when interpreting the results. As the subjects were

  15. Pre-exposure Schedule Effects on Generalization of Taste Aversion and Palatability for Thirsty and Not Thirsty Rats

    Directory of Open Access Journals (Sweden)

    Rocío Angulo

    2018-06-01

    Full Text Available The study reported four experiments aiming to test the effects of the pre-exposure schedule and water deprivation on the generalization of a conditioned taste aversion in rats, with a particular focus on testing whether or not the concurrent schedule might enhance generalization. In two experiments, non-water-deprived rats received concurrent, intermixed, or blocked exposure to a sweet-acid solution and a salty-acid solution before conditioning of one of these compounds and testing of both flavors. During pre-exposure, the rats consumed a greater amount of the sweet-acid solution than the salty-acid solution (Experiments 1 and 2, consumption of the former increasing during pre-exposure while consumption of the latter decreased (Experiment 1. Furthermore, consumption of the salty-acid solution was lower during concurrent than intermixed or blocked pre-exposure (Experiment 1 and 2 while consumption of the sweet-acid solution was greater during intermixed than concurrent or blocked pre-exposure (Experiment 1. It is discussed whether the pre-exposure schedule might modify stimulus perception beyond the mere enhancement of stimulus differentiation, by, for instance, affecting the palatability of gustatory stimuli. Evidence for enhanced generalization after concurrent pre-exposure was not found for either deprived (Experiments 1, 2, and 3 or non-deprived rats (Experiments 3 and 4, with deprivation leading to a general increase in consumption of both the conditioned and test flavors. This then raised the question of whether or not concurrent pre-exposure to flavors always increases generalization between them. The present study highlights the importance of this issue for various accounts of perceptual learning.

  16. General Purpose (office) Network reorganisation

    CERN Multimedia

    IT Department

    2016-01-01

    On Saturday 27 August, the IT Department’s Communication Systems group will perform a major reorganisation of CERN’s General Purpose Network.   This reorganisation will cause network interruptions on Saturday 27 August (and possibly Sunday 28 August) and will be followed by a change to the IP addresses of connected systems that will come into effect on Monday 3 October. For further details and information about the actions you may need to take, please see: https://information-technology.web.cern.ch/news/general-purpose-office-network-reorganisation.

  17. A qualitative study of collaboration in general practice: understanding the general practice nurse's role.

    Science.gov (United States)

    McInnes, Susan; Peters, Kath; Bonney, Andrew; Halcomb, Elizabeth

    2017-07-01

    To explore the nature of collaboration between registered nurses and general practitioners in Australian general practice. There is international recognition that collaboration between health professionals can improve care coordination, enhance health outcomes, optimise the work environment and reduce healthcare costs. However, effective collaboration requires a clear understanding of each team member's role. A qualitative approach guided by Naturalistic Inquiry was used to elicit and interpret participant narratives. Eight general practitioners and fourteen registered nurses working in general practice were purposefully recruited. Data were collected via individual, semi-structured face-to-face interviews during February to May 2015. Interviews were audio recorded and transcribed verbatim. Data were analysed using thematic analysis. Data revealed three overarching themes. This study presents the data for the overarching theme 'Understanding the general practice registered nurse's role'. Many general practitioner participants lacked clarity around the role and scope of practice of the registered nurse. At the same time, nursing participants often articulated their role as an assistant rather than as an independent health professional. This limited collaboration and the nurses' role within the team. Collaboration was enhanced when general practitioners actively sought an understanding of the registered nurses scope of practice. Clarifying the nurses' role promotes collaboration and supports nurses to work to the full extent of their practice. This is important in terms of optimising the nurses' role within the team and reinforcing their professional identity. Identification of key issues around understanding the nurses' role may help inform strategies that improve collaboration and workplace relations. © 2016 John Wiley & Sons Ltd.

  18. Generalized string theory mapping relations between gravity and gauge theory

    International Nuclear Information System (INIS)

    Bjerrum-Bohr, N.E.J.

    2003-01-01

    A previous study of the Kawai, Lewellen and Tye (KLT) relations between gravity and gauge theories, imposed by the relationship of closed and open strings, are here extended in the light of general relativity and Yang-Mills theory as effective field theories. We discuss the possibility of generalizing the traditional KLT mapping in this effective setting. A generalized mapping between the effective Lagrangians of gravity and Yang-Mills theory is presented, and the corresponding operator relations between gauge and gravity theories at the tree level are further explored. From this generalized mapping remarkable diagrammatic relations are found, linking diagrams in gravity and Yang-Mills theory, as well as diagrams in pure effective Yang-Mills theory. Also the possibility of a gravitational coupling to an antisymmetric field in the gravity scattering amplitude is considered, and shown to allow for mixed open-closed string solutions, i.e., closed heterotic strings

  19. Vocational and General Education of Girls and Boys in Tunisia: The Effects of Income and Parental Education

    Directory of Open Access Journals (Sweden)

    Mohamed Siala

    2014-05-01

    Full Text Available Throughout Tunisia, basic education is compulsory. Children are required to enroll for at least 9 years from age 6. This paper examines gender differences in education choice of upper basic education of youths aged 15–24 in Tunisia. To investigate the factors that influence an individual’s choice between vocational education, general education (secondary and high education and leaving school, the paper estimates a multinomial probit model of education choice. We focus on the impact of household income, parental education, sector of economic activity of father, household size, urban location and region of residence on investments in children. These issues are addressed using data from the 2010 National PopulationEmployment Survey that provided information on educational attainment and vocational training of more than 55,000 youths aged 15-24. The findings of this paper suggest that there are gender differences in education choice. Increases in permanent income contribute more to the probabilities of the two types of education of girls than of boys. Parental education has a positive significant effect on their attitudes towards children education and the impact of mother’s higher education was more important for the education of boys than of girls. While, father’s coefficient estimates show the relative benefit to girls general education. Children whose fathers work in agriculture are at disadvantage. The negative effect on girls’ education was larger than on boys’ at the two streams of education. The coefficient estimates on the manufacturing sector increase the probabilities of receiving general education and decrease the probabilities of undertaking vocational education for both girls and boys.

  20. The Effects of Word Box Instruction on Acquisition, Generalization, and Maintenance of Decoding and Spelling Skills for First Graders

    Science.gov (United States)

    Alber-Morgan, Sheila R.; Joseph, Laurice M.; Kanotz, Brittany; Rouse, Christina A.; Sawyer, Mary R.

    2016-01-01

    This study examined the effects of implementing word boxes as a supplemental instruction method on the acquisition, maintenance, and generalization of word identification and spelling. Word box intervention consists of using manipulatives to learn phonological decoding skills. The participants were three African-American urban first graders…

  1. Possible Simple Structures of the Universe to Include General Relativity Effects

    Directory of Open Access Journals (Sweden)

    Corneliu BERBENTE

    2017-12-01

    Full Text Available The general relativity describes the universe properties, the gravity playing a fundamental role. One uses a metric tensor in a Riemann space, g  , which should be in agreement with a mass (or energy tensor in order to satisfy the Einstein equation of the general relativity [1]. This equation contains the Ricci curvature as well. In general, applications are done considering that a chosen metric is valid without region limits. In fact, the density of the energy whose distribution is however unknown is variable in universe; therefore, the metrics need to be adapted to different regions. For this reason one suggests to start with a simple, average mass-energy distribution that could represent in a first step the actual universe. This suggestion is in agreement with the symmetrical distribution of equal spheres existing in a model of the early universe given by one of the authors. Two kinds of distribution are given. The possibility of black holes formation is studied and a criterion is given.

  2. The Effect of Different Modes of English Captioning on EFL learners’ General Listening Comprehension: Full text Vs. Keyword Captions

    Directory of Open Access Journals (Sweden)

    Sorayya Behroozizad

    2015-08-01

    Full Text Available This study investigated the effect of different modes of English captioning on EFL learners’ general listening comprehension. To this end, forty five intermediate-level learners were selected based on their scores on a standardized English proficiency test (PET to carry out the study. Then, the selected participants were randomly assigned into two experimental groups (full-captions and keyword-captions and one control group (no-captions. Research instrumentation included a pre-test and a post-test following an experimental design. Participants took a pre-test and a post-test containing 50 multiple-choice questions (25question for pre-test and 25 question for post-test selected from a standard listening test PET, and also 15 treatment sessions. The findings showed significant differences among full-captions, keyword-captions, and no-captions in terms of their effect on learners’ general listening comprehension. This study provided some pedagogical implications for teaching listening through using different modes of captions. Keywords: Caption, full caption, keyword caption, listening comprehension

  3. The Generalized Higher Criticism for Testing SNP-Set Effects in Genetic Association Studies

    Science.gov (United States)

    Barnett, Ian; Mukherjee, Rajarshi; Lin, Xihong

    2017-01-01

    It is of substantial interest to study the effects of genes, genetic pathways, and networks on the risk of complex diseases. These genetic constructs each contain multiple SNPs, which are often correlated and function jointly, and might be large in number. However, only a sparse subset of SNPs in a genetic construct is generally associated with the disease of interest. In this article, we propose the generalized higher criticism (GHC) to test for the association between an SNP set and a disease outcome. The higher criticism is a test traditionally used in high-dimensional signal detection settings when marginal test statistics are independent and the number of parameters is very large. However, these assumptions do not always hold in genetic association studies, due to linkage disequilibrium among SNPs and the finite number of SNPs in an SNP set in each genetic construct. The proposed GHC overcomes the limitations of the higher criticism by allowing for arbitrary correlation structures among the SNPs in an SNP-set, while performing accurate analytic p-value calculations for any finite number of SNPs in the SNP-set. We obtain the detection boundary of the GHC test. We compared empirically using simulations the power of the GHC method with existing SNP-set tests over a range of genetic regions with varied correlation structures and signal sparsity. We apply the proposed methods to analyze the CGEM breast cancer genome-wide association study. Supplementary materials for this article are available online. PMID:28736464

  4. The median hazard ratio: a useful measure of variance and general contextual effects in multilevel survival analysis.

    Science.gov (United States)

    Austin, Peter C; Wagner, Philippe; Merlo, Juan

    2017-03-15

    Multilevel data occurs frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models (MLRM). MLRM incorporate cluster-specific random effects which allow one to partition the total individual variance into between-cluster variation and between-individual variation. Statistically, MLRM account for the dependency of the data within clusters and provide correct estimates of uncertainty around regression coefficients. Substantively, the magnitude of the effect of clustering provides a measure of the General Contextual Effect (GCE). When outcomes are binary, the GCE can also be quantified by measures of heterogeneity like the Median Odds Ratio (MOR) calculated from a multilevel logistic regression model. Time-to-event outcomes within a multilevel structure occur commonly in epidemiological and medical research. However, the Median Hazard Ratio (MHR) that corresponds to the MOR in multilevel (i.e., 'frailty') Cox proportional hazards regression is rarely used. Analogously to the MOR, the MHR is the median relative change in the hazard of the occurrence of the outcome when comparing identical subjects from two randomly selected different clusters that are ordered by risk. We illustrate the application and interpretation of the MHR in a case study analyzing the hazard of mortality in patients hospitalized for acute myocardial infarction at hospitals in Ontario, Canada. We provide R code for computing the MHR. The MHR is a useful and intuitive measure for expressing cluster heterogeneity in the outcome and, thereby, estimating general contextual effects in multilevel survival analysis. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd.

  5. 7 CFR 2610.1 - General statement.

    Science.gov (United States)

    2010-01-01

    ... and effectiveness; to prevent and detect fraud and abuse in such programs and operations; and to keep...) Serve as liaison official for the Department for all audits of USDA performed by the General Accounting..., and effectiveness, and to prevent and detect fraud and abuse in the administration of the Department's...

  6. arXiv Effective description of general extensions of the Standard Model: the complete tree-level dictionary

    CERN Document Server

    de Blas, J.; Perez-Victoria, M.; Santiago, J.

    2018-03-19

    We compute all the tree-level contributions to the Wilson coefficients of the dimension-six Standard-Model effective theory in ultraviolet completions with general scalar, spinor and vector field content and arbitrary interactions. No assumption about the renormalizability of the high-energy theory is made. This provides a complete ultraviolet/infrared dictionary at the classical level, which can be used to study the low-energy implications of any model of interest, and also to look for explicit completions consistent with low-energy data.

  7. The Effect of Student Working Group Establishment on Teaching General Embryology Course to Medical Students

    Directory of Open Access Journals (Sweden)

    Mozafar Khazaei

    2012-11-01

    Full Text Available Introduction: Quantitative and qualitative enhancement of educational activities is an essential issue. Learners’ cooperation in the teaching process in order to increase teaching effectiveness and promotion is considered significant. The aim of the present study was to determine the effect of establishment of student working group on the teaching general embryology course to medical students.Methods: Ten students (1% of medical embryology course were selected to analyze the topics to be taught before each session according to lesson plan, and observe the whole teaching process during lesson presentation. Then, having asked the other students’ viewpoints and discussing with one another, they provided the teacher with a written report on the strengths and weaknesses of the teaching and its problems. The teacher analyzed the problems proposed by the working group to improve teaching process in the next session. At the end of the semester, a questionnaire was administered to all the participants. Data were analyzed using descriptive statistics.Results: The mean of students’ scores was 74.26%. The most important findings obtained in this study included positive role of film projection in teaching the materials (95.34%, significance of presentation of various pictures from different books (88.4%, changing students’ attitude toward application of embryology in different diseases (86%, and repetition of previous session’s pictures (83.75%. The weak points mentioned, however, were physical problems of the classroom and deficiency of audio visual equipment.Conclusion: Student working group has a positive impact on the teaching medical general embryology.

  8. Nutrition communication in general practice

    NARCIS (Netherlands)

    Dillen, van S.M.E.; Hiddink, G.J.; Koelen, M.A.; Graaf, de C.; Woerkum, van C.M.J.

    2006-01-01

    General practitioners (GPs) are frequently confronted with patients who suffer from obesity or other nutrition-related diseases, such as diabetes and coronary heart disease. There is increasing evidence that nutrition communication is effective in changing nutrition behaviour. Moreover, it is widely

  9. Noise suppression via generalized-Markovian processes

    Science.gov (United States)

    Marshall, Jeffrey; Campos Venuti, Lorenzo; Zanardi, Paolo

    2017-11-01

    It is by now well established that noise itself can be useful for performing quantum information processing tasks. We present results which show how one can effectively reduce the error rate associated with a noisy quantum channel by counteracting its detrimental effects with another form of noise. In particular, we consider the effect of adding on top of a purely Markovian (Lindblad) dynamics, a more general form of dissipation, which we refer to as generalized-Markovian noise. This noise has an associated memory kernel and the resulting dynamics are described by an integrodifferential equation. The overall dynamics are characterized by decay rates which depend not only on the original dissipative time scales but also on the new integral kernel. We find that one can engineer this kernel such that the overall rate of decay is lowered by the addition of this noise term. We illustrate this technique for the case where the bare noise is described by a dephasing Pauli channel. We analytically solve this model and show that one can effectively double (or even triple) the length of the channel, while achieving the same fidelity, entanglement, and error threshold. We numerically verify this scheme can also be used to protect against thermal Markovian noise (at nonzero temperature), which models spontaneous emission and excitation processes. A physical interpretation of this scheme is discussed, whereby the added generalized-Markovian noise causes the system to become periodically decoupled from the background Markovian noise.

  10. The Effects of General and Epidural Anaesthesia in Maternal’s Stress Hormones and Blood Gases in Elective Cesarean Section

    Directory of Open Access Journals (Sweden)

    Meral EZBERCI

    2005-09-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the effects of general and epidural anaesthesia in maternal’s stress hormones and blood gases in elective cesarean section.\tMATERIALS-METHODS: 50 patients in ASA II (American Society of Anesthesiology class who would undergo elective cesarean section in University of Kahramanmaras Sutcuimam, Department of Anaesthesiology and Reanimation included in the study and randomized into two equal groups (General anaesthesia: Group G and Epidural anaesthesia: Group E. In both groups, maternal stress hormones (TSH, cortisol, and insulin and blood gases were studied. All patients received famotidine and granisetron iv 30 min before operations in premedication room. In the general anaesthesia group; aritmal, propofol, and succinylcholine was used for induction and muscle relaxation. Following the induction, positive pressure ventilation of the lungs was started immediately using a 50% N2O + O2 mixture. After delivery of the baby, anaesthesia and muscle relaxation was maintained by 50% N2O +O2, 0,5-1% MAC isoflurane, and cisatracurium. In the epidural anaesthesia group; epidural anaesthesia was performed with 0,375 % bupivacaine. The epidural needle inserted through L2-3 or L3-4 interspace. After achieving T4-5 neural blockade, the operation was started. In general anaesthesia group; blood samples for maternal stres hormones were taken before induction and after delivery of the baby. In epidural anaesthesia group; blood samples for maternal stres hormones were taken catheter placement and after delivery of the baby. Blood samples for maternal blood gases were taken after the delivery of the baby.\tRESULTS: In both groups; there were statistically significant decrease in maternal TSH and insulin and there were no statistically significant changes in maternal cortisol. In maternal blood gases analyses, only PO2 and SO2 changes were statistically significant between two groups.\tCONCLUSION: With these results

  11. The General Factor of Personality: A General Critique.

    Science.gov (United States)

    Revelle, William; Wilt, Joshua

    2013-10-01

    Recently, it has been proposed that all non-cognitive measures of personality share a general factor of personality. A problem with many of these studies is a lack of clarity in defining a general factor. In this paper we address the multiple ways in which a general factor has been identified and argue that many of these approaches find factors that are not in fact general. Through the use of artificial examples, we show that a general factor is not: The first factor or component of a correlation or covariance matrix.The first factor resulting from a bifactor rotation or biquartimin transformationNecessarily the result of a confirmatory factor analysis forcing a bifactor solution We consider how the definition of what constitutes a general factor can lead to confusion, and we will demonstrate alternative ways of estimating the general factor saturation that are more appropriate.

  12. 10 CFR 436.102 - General operations plan format and content.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false General operations plan format and content. 436.102... PROGRAMS Guidelines for General Operations Plans § 436.102 General operations plan format and content. (a... effective date of these guidelines, a general operations 10-year plan which shall consist of two parts, an...

  13. The General Factor of Personality: A General Critique

    OpenAIRE

    Revelle, William; Wilt, Joshua

    2013-01-01

    Recently, it has been proposed that all non-cognitive measures of personality share a general factor of personality. A problem with many of these studies is a lack of clarity in defining a general factor. In this paper we address the multiple ways in which a general factor has been identified and argue that many of these approaches find factors that are not in fact general. Through the use of artificial examples, we show that a general factor is not: The first factor or component of a correla...

  14. On a Generalized Hankel Type Convolution of Generalized Functions

    Indian Academy of Sciences (India)

    Generalized Hankel type transformation; Parserval relation; generalized ... The classical generalized Hankel type convolution are defined and extended to a class of generalized functions. ... Proceedings – Mathematical Sciences | News.

  15. General relativity

    International Nuclear Information System (INIS)

    Gourgoulhon, Eric

    2013-01-01

    The author proposes a course on general relativity. He first presents a geometrical framework by addressing, presenting and discussion the following notions: the relativistic space-time, the metric tensor, Universe lines, observers, principle of equivalence and geodesics. In the next part, he addresses gravitational fields with spherical symmetry: presentation of the Schwarzschild metrics, radial light geodesics, gravitational spectral shift (Einstein effect), orbitals of material objects, photon trajectories. The next parts address the Einstein equation, black holes, gravitational waves, and cosmological solutions. Appendices propose a discussion of the relationship between relativity and GPS, some problems and their solutions, and Sage codes

  16. 7 CFR 900.300 - General.

    Science.gov (United States)

    2010-01-01

    ... Conduct of Referenda To Determine Producer Approval of Milk Marketing Orders To Be Made Effective Pursuant to Agricultural Marketing Agreement Act of 1937, as Amended § 900.300 General. Unless otherwise... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (Marketing Agreements...

  17. Effects of Students' Pre- and Post-Laboratory Concept Maps on Students' Attitudes toward Chemistry Laboratory in University General Chemistry

    Science.gov (United States)

    Kilic, Ziya; Kaya, Osman Nafiz; Dogan, Alev

    2004-01-01

    The purpose of this study was to investigate the effects of scientific discussions based on student-constructed pre- and post-laboratory concept maps on students' attitudes toward chemistry laboratory in the university general chemistry. As part of instruction, during the first four laboratory sessions, students were taught how to construct and…

  18. The Effect of Different Modes of English Captioning on EFL Learners' General Listening Comprehension: Full Text vs. Keyword Captions

    Science.gov (United States)

    Behroozizad, Sorayya; Majidi, Sudabeh

    2015-01-01

    This study investigated the effect of different modes of English captioning on EFL learners' general listening comprehension. To this end, forty-five intermediate-level learners were selected based on their scores on a standardized English proficiency test (PET) to carry out the study. Then, the selected participants were randomly assigned into…

  19. Effects of different types of anaesthesia (regional vs general) on serum NO and TNF-α levels in surgical patients

    International Nuclear Information System (INIS)

    Li Hong

    2006-01-01

    Objective: To study the effect of anesthesia on changes of serum NO and TNF-α levels in surgical patients. Methods: Serum NO (with biochemical method) and TNF-α (with RIA) levels were determined for 3 times in 31 patients operated under regional anesthesia and 31 patients operated under general anesthesia (both for benign gastric ulcer). The levels were measured before induction of anesthesia, at the beginning of operation, and 1 hr later. Results: In patients under regional anesthesia, both the NO and TNF-α levels increased significantly at the beginning of operation and, 1 hr later, though dropped, remained significantly higher than the levels before induction (P<0.05). NO significant changes of the levels were observed in patients under general anesthesia throughout the operation, and the levels were, as a whole, significantly lower than the levels under regional anesthesia (P<0.05). Conclusion: General anesthesia (combined intravenous and inhalation) could abolish the increase of serum NO and TNF-α levels duning operation. (authors)

  20. Measuring the individual benefit of a medical or behavioral treatment using generalized linear mixed-effects models.

    Science.gov (United States)

    Diaz, Francisco J

    2016-10-15

    We propose statistical definitions of the individual benefit of a medical or behavioral treatment and of the severity of a chronic illness. These definitions are used to develop a graphical method that can be used by statisticians and clinicians in the data analysis of clinical trials from the perspective of personalized medicine. The method focuses on assessing and comparing individual effects of treatments rather than average effects and can be used with continuous and discrete responses, including dichotomous and count responses. The method is based on new developments in generalized linear mixed-effects models, which are introduced in this article. To illustrate, analyses of data from the Sequenced Treatment Alternatives to Relieve Depression clinical trial of sequences of treatments for depression and data from a clinical trial of respiratory treatments are presented. The estimation of individual benefits is also explained. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  1. Cost effectiveness of physiotherapy, manual therapy, and general practitioner care for neck pain: economic evaluation alongside a randomised controlled trial

    NARCIS (Netherlands)

    Korthals-de Bos, Ingeborg B. C.; Hoving, Jan L.; van Tulder, Maurits W.; Rutten-van Mölken, Maureen P. M. H.; Adèr, Herman J.; de Vet, Henrica C. W.; Koes, Bart W.; Vondeling, Hindrik; Bouter, Lex M.

    2003-01-01

    OBJECTIVE: To evaluate the cost effectiveness of physiotherapy, manual therapy, and care by a general practitioner for patients with neck pain. DESIGN: Economic evaluation alongside a randomised controlled trial. SETTING: Primary care. PARTICIPANTS: 183 patients with neck pain for at least two weeks

  2. General Base-General Acid Catalysis in Human Histone Deacetylase 8.

    Science.gov (United States)

    Gantt, Sister M Lucy; Decroos, Christophe; Lee, Matthew S; Gullett, Laura E; Bowman, Christine M; Christianson, David W; Fierke, Carol A

    2016-02-09

    Histone deacetylases (HDACs) regulate cellular processes such as differentiation and apoptosis and are targeted by anticancer therapeutics in development and in the clinic. HDAC8 is a metal-dependent class I HDAC and is proposed to use a general acid-base catalytic pair in the mechanism of amide bond hydrolysis. Here, we report site-directed mutagenesis and enzymological measurements to elucidate the catalytic mechanism of HDAC8. Specifically, we focus on the catalytic function of Y306 and the histidine-aspartate dyads H142-D176 and H143-D183. Additionally, we report X-ray crystal structures of four representative HDAC8 mutants: D176N, D176N/Y306F, D176A/Y306F, and H142A/Y306F. These structures provide a useful framework for understanding enzymological measurements. The pH dependence of kcat/KM for wild-type Co(II)-HDAC8 is bell-shaped with two pKa values of 7.4 and 10.0. The upper pKa reflects the ionization of the metal-bound water molecule and shifts to 9.1 in Zn(II)-HDAC8. The H142A mutant has activity 230-fold lower than that of wild-type HDAC8, but the pKa1 value is not altered. Y306F HDAC8 is 150-fold less active than the wild-type enzyme; crystal structures show that Y306 hydrogen bonds with the zinc-bound substrate carbonyl, poised for transition state stabilization. The H143A and H142A/H143A mutants exhibit activity that is >80000-fold lower than that of wild-type HDAC8; the buried D176N and D176A mutants have significant catalytic effects, with more subtle effects caused by D183N and D183A. These enzymological and structural studies strongly suggest that H143 functions as a single general base-general acid catalyst, while H142 remains positively charged and serves as an electrostatic catalyst for transition state stabilization.

  3. An investigation of the effectiveness of the modular general English ...

    African Journals Online (AJOL)

    The findings of the study show that the modular system should be discontinued as it has certain ... 2012), the academic English needs of university students are generally neglected in .... University through qualitative and quantitative data from the perspective of students, ..... The major problems with the modular sys-.

  4. Effects of cavity-cavity interaction on the entanglement dynamics of a generalized double Jaynes-Cummings model

    Science.gov (United States)

    Pandit, Mahasweta; Das, Sreetama; Singha Roy, Sudipto; Shekhar Dhar, Himadri; Sen, Ujjwal

    2018-02-01

    We consider a generalized double Jaynes-Cummings model consisting of two isolated two-level atoms, each contained in a lossless cavity that interact with each other through a controlled photon-hopping mechanism. We analytically show that at low values of such a mediated cavity-cavity interaction, the temporal evolution of entanglement between the atoms, under the effects of cavity perturbation, exhibits the well-known phenomenon of entanglement sudden death (ESD). Interestingly, for moderately large interaction values, a complete preclusion of ESD is achieved, irrespective of its value in the initial atomic state. Our results provide a model to sustain entanglement between two atomic qubits, under the adverse effect of cavity induced perturbation, by introducing a non-intrusive inter-cavity photon exchange that can be physically realized through cavity-QED setups in contemporary experiments.

  5. Generalized Bell-inequality experiments and computation

    Energy Technology Data Exchange (ETDEWEB)

    Hoban, Matty J. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Department of Computer Science, University of Oxford, Wolfson Building, Parks Road, Oxford OX1 3QD (United Kingdom); Wallman, Joel J. [School of Physics, The University of Sydney, Sydney, New South Wales 2006 (Australia); Browne, Dan E. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

    2011-12-15

    We consider general settings of Bell inequality experiments with many parties, where each party chooses from a finite number of measurement settings each with a finite number of outcomes. We investigate the constraints that Bell inequalities place upon the correlations possible in local hidden variable theories using a geometrical picture of correlations. We show that local hidden variable theories can be characterized in terms of limited computational expressiveness, which allows us to characterize families of Bell inequalities. The limited computational expressiveness for many settings (each with many outcomes) generalizes previous results about the many-party situation each with a choice of two possible measurements (each with two outcomes). Using this computational picture we present generalizations of the Popescu-Rohrlich nonlocal box for many parties and nonbinary inputs and outputs at each site. Finally, we comment on the effect of preprocessing on measurement data in our generalized setting and show that it becomes problematic outside of the binary setting, in that it allows local hidden variable theories to simulate maximally nonlocal correlations such as those of these generalized Popescu-Rohrlich nonlocal boxes.

  6. Generalized Bell-inequality experiments and computation

    International Nuclear Information System (INIS)

    Hoban, Matty J.; Wallman, Joel J.; Browne, Dan E.

    2011-01-01

    We consider general settings of Bell inequality experiments with many parties, where each party chooses from a finite number of measurement settings each with a finite number of outcomes. We investigate the constraints that Bell inequalities place upon the correlations possible in local hidden variable theories using a geometrical picture of correlations. We show that local hidden variable theories can be characterized in terms of limited computational expressiveness, which allows us to characterize families of Bell inequalities. The limited computational expressiveness for many settings (each with many outcomes) generalizes previous results about the many-party situation each with a choice of two possible measurements (each with two outcomes). Using this computational picture we present generalizations of the Popescu-Rohrlich nonlocal box for many parties and nonbinary inputs and outputs at each site. Finally, we comment on the effect of preprocessing on measurement data in our generalized setting and show that it becomes problematic outside of the binary setting, in that it allows local hidden variable theories to simulate maximally nonlocal correlations such as those of these generalized Popescu-Rohrlich nonlocal boxes.

  7. Weak lensing in generalized gravity theories

    International Nuclear Information System (INIS)

    Acquaviva, Viviana; Baccigalupi, Carlo; Perrotta, Francesca

    2004-01-01

    We extend the theory of weak gravitational lensing to cosmologies with generalized gravity, described in the Lagrangian by a generic function depending on the Ricci scalar and a nonminimal coupled scalar field. We work out the generalized Poisson equations relating the dynamics of the fluctuating components to the two gauge-invariant scalar gravitational potentials, fixing the contributions from the modified background expansion and fluctuations. We show how the lensing equation gets modified by the cosmic expansion as well as by the presence of anisotropic stress, which is non-null at the linear level both in scalar-tensor gravity and in theories where the gravitational Lagrangian term features a nonminimal dependence on the Ricci scalar. Starting from the geodesic deviation, we derive the generalized expressions for the shear tensor and projected lensing potential, encoding the spacetime variation of the effective gravitational constant and isolating the contribution of the anisotropic stress, which introduces a correction due to the spatial correlation between the gravitational potentials. Finally, we work out the expressions of the lensing convergence power spectrum as well as the correlation between the lensing potential and the integrated Sachs-Wolfe effect affecting cosmic microwave background total intensity and polarization anisotropies. To illustrate phenomenologically the effects, we work out approximate expressions for the quantities above in extended quintessence scenarios where the scalar field coupled to gravity plays the role of the dark energy

  8. Generalized Euler transformation for summing strongly divergent Rayleigh-Schroedinger perturbation series: the Zeeman effect

    International Nuclear Information System (INIS)

    Silverman, J.N.

    1983-01-01

    A generalized Euler transformation (GET) is introduced which provides a powerful alternative method of accurately summing strongly divergent Rayleigh-Schroedinger (RS) perturbation series when other summability methods fail or are difficult to apply. The GET is simple to implement and, unlike a number of other summation procedures, requires no a priori knowledge of the analytic properties of the function underlying the RS series. Application of the GET to the difficult problem of the RS weak-field ground-state eigenvalue series of the hydrogen atom in a magnetic field (quadratic Zeeman effect) yields sums of good accuracy over a very wide range of field strengths up to the most intense fields of 10 14 G. The GET results are compared with those obtained by other summing methods

  9. Effects of detector-source distance and detector bias voltage variations on time resolution of general purpose plastic scintillation detectors.

    Science.gov (United States)

    Ermis, E E; Celiktas, C

    2012-12-01

    Effects of source-detector distance and the detector bias voltage variations on time resolution of a general purpose plastic scintillation detector such as BC400 were investigated. (133)Ba and (207)Bi calibration sources with and without collimator were used in the present work. Optimum source-detector distance and bias voltage values were determined for the best time resolution by using leading edge timing method. Effect of the collimator usage on time resolution was also investigated. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Representation of Concrete Logics and Concrete Generalized Orthomodular Posets

    Science.gov (United States)

    Pulmannová, S.; Riečanová, Z.; Vinceková, E.

    2014-04-01

    In the present paper, we deal with the question when an effect algebra, resp. a generalized effect algebra, can be represented in the projection lattice of a Hilbert space. We show that such representability is closely related to the existence of a rich set of two-valued and Jauch-Piron states, resp. generalized two-valued and Jauch-Piron states. AMS Classification: Primary 81Q10, Secondary 03G12.

  11. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    OpenAIRE

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2011-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gende...

  12. The Effectiveness of Abstinence-Based/Faith-Based Addiction Quitting Courses on General and Coping Self-Efficacy

    Directory of Open Access Journals (Sweden)

    Hosin Nazari, Sh

    2010-05-01

    Full Text Available Aim: One of the influential elements in the life of an individual is his or her level of self efficacy. This research aimed to study the effectiveness of abstinence-based/faith-based addiction quitting courses on general and coping self efficacy of the people who want to quit opium addiction through these courses in Tehran city. Method: In semi experimental research design 80 people who referred to abstinence-based/faith-based addiction quitting courses were selected by census method. General self efficacy questionnaire of Jerusalem and Schwartzer (1981 and coping self-efficacy questionnaire of Chesney (2006 administered among selected sample before and after treatment. Results: The results of paired t-test indicated that abstinence-based/faith-based addiction quitting courses have a significant influence on the skills of impeding negative thoughts and excitements and gaining friends’ and colleagues’ support. Conclusion: The findings of this research concur with the findings of similar researches, and indicated with appropriate strategies of training self-efficacy beliefs can be improved and boosted.

  13. Orographic effects on tropical climate in a coupled ocean-atmosphere general circulation model

    Science.gov (United States)

    Okajima, Hideki

    Large-scale mountain modifies the atmospheric circulation directly through dynamic and thermodynamic process, and also indirectly through the interaction with the ocean. To investigate orographic impacts on tropical climate, a fully coupled general circulation model (CGCM) is developed by coupling a state-of-the-art atmospheric general circulation model and an ocean general circulation model. With realistic boundary conditions, the CGCM produces a reasonable climatology of sea surface temperature (SST), surface winds, and precipitation. When global mountains are removed, the model climatology displays substantial changes in both the mean-state and the seasonal cycle. The equatorial eastern Pacific SST acquires a semi-annual component as inter-tropical convergence zone (ITCZ) flips and flops across the equator following the seasonal migration of the sun. Without the Andes, wet air flows into the southeastern tropical Pacific from the humid Amazon, which weakens the meridional asymmetry during the Peruvian warm season (February-April). In addition, the northeasterly trade winds are enhanced north of the equator without the orographic blocking of Central American mountains and cools SST. Triggered by the SST cooling north and moistening south of the equator, the wind-evaporation-SST (WES) feedback further weakens the meridional asymmetry and prolongs the southern ITCZ. In the Atlantic Ocean, the equatorial cold tongue is substantially strengthened and develops a pronounced annual cycle in the absence of mountains. The easterly winds are overall enhanced over the equatorial Atlantic without orographic heating over the African highlands, developing a zonal asymmetry strengthened by the Bjerknes feedback. In the Indian Ocean, the thermocline shoals eastward and an equatorial cold tongue appears twice a year. During boreal summer, the Findlater jet is greatly weakened off Somalia and SST warms in the western Indian Ocean, forcing the equatorial easterly winds amplified

  14. The Confrontation between General Relativity and Experiment

    Directory of Open Access Journals (Sweden)

    Clifford M. Will

    2014-06-01

    Full Text Available The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed and updated. Einstein’s equivalence principle (EEP is well supported by experiments such as the Eötvös experiment, tests of local Lorentz invariance and clock experiments. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, the Nordtvedt effect in lunar motion, and frame-dragging. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse–Taylor binary pulsar, and a growing family of other binary pulsar systems is yielding new tests, especially of strong-field effects. Current and future tests of relativity will center on strong gravity and gravitational waves.

  15. The Confrontation between General Relativity and Experiment.

    Science.gov (United States)

    Will, Clifford M

    2014-01-01

    The status of experimental tests of general relativity and of theoretical frameworks for analyzing them is reviewed and updated. Einstein's equivalence principle (EEP) is well supported by experiments such as the Eötvös experiment, tests of local Lorentz invariance and clock experiments. Ongoing tests of EEP and of the inverse square law are searching for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, the Nordtvedt effect in lunar motion, and frame-dragging. Gravitational wave damping has been detected in an amount that agrees with general relativity to better than half a percent using the Hulse-Taylor binary pulsar, and a growing family of other binary pulsar systems is yielding new tests, especially of strong-field effects. Current and future tests of relativity will center on strong gravity and gravitational waves.

  16. Nonlinear dynamics of the patient’s response to drug effect during general anesthesia

    Science.gov (United States)

    Ionescu, Clara; Tenreiro Machado, Jose; De Keyser, Robin; Decruyenaere, Johan; Struys, Michel M. R. F.

    2015-03-01

    In today's healthcare paradigm, optimal sedation during anesthesia plays an important role both in patient welfare and in the socio-economic context. For the closed-loop control of general anesthesia, two drugs have proven to have stable, rapid onset times: propofol and remifentanil. These drugs are related to their effect in the bispectral index, a measure of EEG signal. In this paper wavelet time-frequency analysis is used to extract useful information from the clinical signals, since they are time-varying and mark important changes in patient's response to drug dose. Model based predictive control algorithms are employed to regulate the depth of sedation by manipulating these two drugs. The results of identification from real data and the simulation of the closed loop control performance suggest that the proposed approach can bring an improvement of 9% in overall robustness and may be suitable for clinical practice.

  17. Teachers' Understanding of Algebraic Generalization

    Science.gov (United States)

    Hawthorne, Casey Wayne

    Generalization has been identified as a cornerstone of algebraic thinking (e.g., Lee, 1996; Sfard, 1995) and is at the center of a rich conceptualization of K-8 algebra (Kaput, 2008; Smith, 2003). Moreover, mathematics teachers are being encouraged to use figural-pattern generalizing tasks as a basis of student-centered instruction, whereby teachers respond to and build upon the ideas that arise from students' explorations of these activities. Although more and more teachers are engaging their students in such generalizing tasks, little is known about teachers' understanding of generalization and their understanding of students' mathematical thinking in this domain. In this work, I addressed this gap, exploring the understanding of algebraic generalization of 4 exemplary 8th-grade teachers from multiple perspectives. A significant feature of this investigation is an examination of teachers' understanding of the generalization process, including the use of algebraic symbols. The research consisted of two phases. Phase I was an examination of the teachers' understandings of the underlying quantities and quantitative relationships represented by algebraic notation. In Phase II, I observed the instruction of 2 of these teachers. Using the lens of professional noticing of students' mathematical thinking, I explored the teachers' enacted knowledge of algebraic generalization, characterizing how it supported them to effectively respond to the needs and queries of their students. Results indicated that teachers predominantly see these figural patterns as enrichment activities, disconnected from course content. Furthermore, in my analysis, I identified conceptual difficulties teachers experienced when solving generalization tasks, in particular, connecting multiple symbolic representations with the quantities in the figures. Moreover, while the teachers strived to overcome the challenges of connecting different representations, they invoked both productive and unproductive

  18. A comparison of the effects of pilates and mckenzie training on pain and general health in men with chronic low back pain: A randomized trial

    Directory of Open Access Journals (Sweden)

    Ali Hasanpour-Dehkordi

    2017-01-01

    Full Text Available Background: Today, chronic low back pain is one of the special challenges in healthcare. There is no unique approach to treat chronic low back pain. A variety of methods are used for the treatment of low back pain, but the effects of these methods have not yet been investigated adequately. Aim: The aim of this study was to compare the effects of Pilates and McKenzie training on pain and general health of men with chronic low back pain. Materials and Methods: Thirty-six patients with chronic low back pain were chosen voluntarily and assigned to three groups of 12 each: McKenzie group, Pilates group, and control group. The Pilates group participated in 1-h exercise sessions, three sessions a week for 6 weeks. McKenzie group performed workouts 1 h a day for 20 days. The control group underwent no treatment. The general health of all participants was measured by the General Health Questionnaire 28 and pain by the McGill Pain Questionnaire. Results: After therapeutic exercises, there was no significant difference between Pilates and McKenzie groups in pain relief (P = 0.327. Neither of the two methods was superior over the other for pain relief. However, there was a significant difference in general health indexes between Pilates and McKenzie groups. Conclusion: Pilates and McKenzie training reduced pain in patients with chronic low back pain, but the Pilates training was more effective to improve general health.

  19. A Theoretical Assessment of Regional Development Effects on the Demand for General Education

    Science.gov (United States)

    Iwahashi, Roki

    2007-01-01

    This study addresses a prospective aspect of general education: through general education, people obtain information about returns to their future specific education, thereby enabling them to choose fields in which they excel. According to that property of education, this paper presents a theoretical framework as a basis for understanding effects…

  20. Generalized 2-vector spaces and general linear 2-groups

    OpenAIRE

    Elgueta, Josep

    2008-01-01

    In this paper a notion of {\\it generalized 2-vector space} is introduced which includes Kapranov and Voevodsky 2-vector spaces. Various kinds of generalized 2-vector spaces are considered and examples are given. The existence of non free generalized 2-vector spaces and of generalized 2-vector spaces which are non Karoubian (hence, non abelian) categories is discussed, and it is shown how any generalized 2-vector space can be identified with a full subcategory of an (abelian) functor category ...

  1. The effects of a long wait for children's dental general anaesthesia.

    Science.gov (United States)

    North, Sarah; Davidson, Lesley E; Blinkhorn, Anthony S; Mackie, Iain C

    2007-03-01

    The purpose of this study was to monitor the effect of an interruption in a service for children who were scheduled to have dental extractions under general anaesthesia (GA). The reasons for offering GA and the treatment given while the service was not available, together with the history of the pain, antibiotic usage and alterations to the number of teeth extracted were recorded. When the GA extraction service stopped, the children who were scheduled to have their teeth extracted were placed on a waiting list. When the service recommenced 6 months later, the children were invited to attend a reassessment. Relevant data were collected at this visit using a proforma. A total of 321 children had their extractions delayed. Only 249 of these attended for a reassessment. During the waiting period, 102 parents (41.0%) reported that their children required analgesics, 71 (28.5%) stated that their children's sleep was disturbed and 82 (32.9%) recorded problems with eating. One hundred and twenty-three children (49.4%) had received antibiotics, with 49 (19.6%) having been prescribed two or more courses. The majority of treatment plans (85.5%) remained unchanged. Many children who had had their extractions delayed suffered further pain and disruption to their life.

  2. The General Aggression Model.

    Science.gov (United States)

    Allen, Johnie J; Anderson, Craig A; Bushman, Brad J

    2018-02-01

    The General Aggression Model (GAM) is a comprehensive, integrative, framework for understanding aggression. It considers the role of social, cognitive, personality, developmental, and biological factors on aggression. Proximate processes of GAM detail how person and situation factors influence cognitions, feelings, and arousal, which in turn affect appraisal and decision processes, which in turn influence aggressive or nonaggressive behavioral outcomes. Each cycle of the proximate processes serves as a learning trial that affects the development and accessibility of aggressive knowledge structures. Distal processes of GAM detail how biological and persistent environmental factors can influence personality through changes in knowledge structures. GAM has been applied to understand aggression in many contexts including media violence effects, domestic violence, intergroup violence, temperature effects, pain effects, and the effects of global climate change. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. HAEMATOMA BLOCK- AN EFFECTIVE ALTERNATIVE TO GENERAL ANAESTHESIA FOR REDUCTION OF DISTAL RADIUS FRACTURES

    Directory of Open Access Journals (Sweden)

    Prabhati Rani Mishra

    2016-12-01

    Full Text Available BACKGROUND Most common fracture in elderly patients is distal radius fracture. The most common method of management is closed reduction and immobilisation. The aim of the study is to compare the analgesic effects of haematoma block and general anaesthesia for closed reduction of distal fracture of radius. MATERIALS AND METHODS A prospective randomised controlled study was carried out among 100 patients of age group between 15-70 years of either sex who had fracture distal radius between 2015-2016. The patients having multiple fractures, pathological fractures or suffering from any organic diseases were excluded from the study. After taking informed written consent, the patients were randomised into two equal groups. In group A, reduction of fracture was done following administration of IV propofol and in group B after infiltration with 2% lignocaine into fracture haematoma site. Pain score was compared by VAS before, during and after manipulation in both the groups. Time taken from presentation at emergency department to reduction and discharge from hospital was also compared. Statistical analysis was done by applying SPSS software. RESULTS 100 patients of mean age 42.5 years, male: female 43:57 with fracture distal radius were studied. Mean time from admission to fracture reduction in group A was 2.64±0.93 hours and in group B 0.90±0.45 hours (P=0.0001. Discharge time from hospital after reduction of fracture in group A was 4.24±0.94 hours and in group B 0.75±0.2 hours (P=0.0001. VAS during reduction in group A was 0 and in group B 0.98±0.8 (P=0.0001. 10 minutes after reduction VAS in group A was 2.28±0.24 and group B 0.72±0.45 (P=0.0001. CONCLUSION For closed reduction of distal radius fracture, haematoma block with lignocaine is safe and effective alternative to intravenous general anaesthesia with propofol.

  4. Disk and dwarf spheroidal galaxies kinematics from general relativity with infrared renormalization group effects

    International Nuclear Information System (INIS)

    Rodrigues, Davi C.; Oliveira, Paulo L.C. de; Fabris, Julio C.; Shapiro, Ilya L.

    2011-01-01

    Full text: The running of coupling constants is a well known phenomenon within Quantum Field Theory. It is also known that the renormalization group method can be extended to quantum field theory on curved space time. Nonetheless, although we know that the beta function of QED go to zero in the infrared limit fast enough to lead to constant charge at the classical level (in conformity with both the Appelquist-Carazzone theorem and experimental data), no analogous proof exists for General Relativity. Some authors have proposed that the infrared beta function of General Relativity is not trivial, and as such certain small running of the gravitational coupling might take place at astrophysical scales, leading in particular to changes on the role of dark matter in galaxies. We review and extend our contribution to infrared Renormalization Group (RG) effects to General Relativity in the context of galaxies, an approach we call RGGR. We extend our previous results by analyzing a larger sample of galaxies, now also including elliptical and dwarf spheroidal galaxies, besides disk galaxies (both LSB and HSB). We compare our RGGR results to both standard dark matter profiles (NFW, Isothermal, Burkert) and alternative models of gravity (MOND, MSTG), showing that the RGGR results are similar in quality to the best dark matter profiles (the cored ones, e.g., Isothermal and Burkert), while displaying a better fitting to the data than NFW, MOND or MSTG. To the latter, we evaluated both the shape of the rotation curve and the expected stellar mass-to-light ratios. Dwarf spheroidal (dSph) galaxies are small galaxies believed to be dominated by dark matter, with the highest fraction do dark matter per baryonic matter. These galaxies provide a strong test to any theory that mimics either all or part of the dark matter behavior. In particular, this is the only type of galaxy that MOND seems incapable of fitting the data. (author)

  5. Generalized canonical formalism and the S-matrix of theories with constraints of the general type

    International Nuclear Information System (INIS)

    Fradkina, T.Ye.

    1987-01-01

    A canonical quantization method is given for systems with first and second class constraints of arbitrary rank. The effectiveness of the method is demonstrated using sample Yang-Mills and gravitational fields. A correct expression is derived for the S-matrix of theories that are momentum-quadratic within the scope of canonical gauges, including ghost fields. Generalized quantization is performed and the S-matrix is derived in configurational space for theories of relativistic membranes representing a generalization of theories of strings to the case of an extended spatial implementation. It is demonstrated that the theory of membranes in n+l-dimensional space is a system with rank-n constraints

  6. General dental practitioner's views on dental general anaesthesia services.

    Science.gov (United States)

    Threlfall, A G; King, D; Milsom, K M; Blinkhom, A S; Tickle, M

    2007-06-01

    Policy has recently changed on provision of dental general anaesthetic services in England. The aim of this study was to investigate general dental practitioners' views about dental general anaesthetics, the reduction in its availability and the impact on care of children with toothache. Qualitative study using semi-structured interviews and clinical case scenarios. General dental practitioners providing NHS services in the North West of England. 93 general dental practitioners were interviewed and 91 answered a clinical case scenario about the care they would provide for a 7-year-old child with multiple decayed teeth presenting with toothache. Scenario responses showed variation; 8% would immediately refer for general anaesthesia, 25% would initially prescribe antibiotics, but the majority would attempt to either restore or extract the tooth causing pain. Interview responses also demonstrated variation in care, however most dentists agree general anaesthesia has a role for nervous children but only refer as a last resort. The responses indicated an increase in inequalities, and that access to services did not match population needs, leaving some children waiting in pain. Most general dental practitioners support moving dental general anaesthesia into hospitals but some believe that it has widened health inequalities and there is also a problem associated with variation in treatment provision. Additional general anaesthetic services in some areas with high levels of tooth decay are needed and evidence based guidelines about caring for children with toothache are required.

  7. A survey on the knowledge, beliefs and behaviour of a general adult population in Malaysia with respect to the adverse effects of medicines.

    Science.gov (United States)

    Jose, Jimmy; Chong, David; Lynn, Tay Szu; Jye, Goh Ee; Jimmy, Beena

    2011-08-01

    The aim of the study was to explore, in the Malaysian general population: knowledge and beliefs of the characteristics in general of medication-related side effects and side effects associated with different types of medicines; behaviour related to the safe use of drugs before and after taking a medication; and behaviour in the event of a medication-related side effect. A 24-item self-administered questionnaire was developed and used to survey the general public living or working in suburban Kuala Lumpur, Malaysia. Eight hundred questionnaires were distributed, face to face, by researchers using quota sampling. Respondents' knowledge, belief and behaviour were analysed and correlated with demographics, medical history and experience of side effects. Six hundred and ten respondents completed the questionnaire giving a response rate of 76.3%. The mean knowledge score for the respondents was 18.4±3.6 out of the maximum possible score of 26. Educational level and experience of side effect had an influence on the knowledge score obtained. Respondents had misconceptions regarding the safety of complementary and alternative medicines (CAMs) and over-the-counter medications. Medication history and previous experience with side effects had a significant influence on the higher behaviour score obtained. The survey has shown moderate results with regard to the knowledge of public regarding safety of medications, and there was evidence of under-estimating the risk of medications, especially CAMs. The misconceptions among the public, and inappropriate behaviour on drug safety-related aspects, is a concern which needs to be addressed in the interventions designed. © 2011 The Authors. IJPP © 2011 Royal Pharmaceutical Society.

  8. The time for doing is not the time for change: effects of general action and inaction goals on attitude retrieval and attitude change.

    Science.gov (United States)

    Albarracín, Dolores; Handley, Ian M

    2011-06-01

    Implicit in many informal and formal principles of psychological change is the understudied assumption that change requires either an active approach or an inactive approach. This issue was systematically investigated by comparing the effects of general action goals and general inaction goals on attitude change. As prior attitudes facilitate preparation for an upcoming persuasive message, general action goals were hypothesized to facilitate conscious retrieval of prior attitudes and therefore hinder attitude change to a greater extent than general inaction goals. Experiment 1 demonstrated that action primes (e.g., "go," "energy") yielded faster attitude report than inaction primes (e.g., "rest," "still") among participants who were forewarned of an upcoming persuasive message. Experiment 2 showed that the faster attitude report identified in Experiment 1 was localized on attitudes toward a message topic participants were prepared to receive. Experiments 3, 4, and 5 showed that, compared with inaction primes, action primes produced less attitude change and less argument scrutiny in response to a counterattitudinal message on a previously forewarned topic. Experiment 6 confirmed that the effects of the primes on attitude change were due to differential attitude retrieval. That is, when attitude expression was induced immediately after the primes, action and inaction goals produced similar amounts of attitude change. In contrast, when no attitude expression was induced after the prime, action goals produced less attitude change than inaction goals. Finally, Experiment 7 validated the assumption that these goal effects can be reduced or reversed when the goals have already been satisfied by an intervening task. 2011 APA, all rights reserved

  9. The Time for Doing is Not the Time for Change: Effects of General Action and Inaction Goals on Attitude Retrieval and Attitude Change

    Science.gov (United States)

    Albarracín, Dolores; Handley, Ian M.

    2011-01-01

    Implicit in many informal and formal principles of psychological change is the understudied assumption that change requires either an active approach or an inactive approach. This issue was systematically investigated by comparing the effects of general action goals and general inaction goals on attitude change. As prior attitudes facilitate preparation for an upcoming persuasive message, general action goals were hypothesized to facilitate conscious retrieval of prior attitudes and therefore hinder attitude change to a greater extent than general inaction goals. Experiment 1 demonstrated that action primes (e.g., “go,” “energy”) yielded faster attitude report than inaction primes (e.g., “rest,” “still”) among participants who were forewarned of an upcoming persuasive message. Experiment 2 showed that the faster attitude report identified in Experiment 1 was localized on attitudes towards a message topic participants were prepared to receive. Experiments 3, 4, and 5 showed that, compared to inaction primes, action primes produced less attitude change and less argument scrutiny in response to a counterattitudinal message on a previously forewarned topic. Experiment 6 confirmed that the effects of the primes on attitude change were due to differential attitude retrieval. That is, when attitude expression was induced immediately after the primes, action and inaction goals produced similar amounts of attitude change. In contrast, when no attitude expression was induced after the prime, action goals produced less attitude change than inaction goals. Finally, Experiment 7 validated the assumption that these goal effects can be reduced or reversed when the goals have already been satisfied by an intervening task. PMID:21639651

  10. 28 CFR 17.11 - Authority of the Assistant Attorney General for Administration.

    Science.gov (United States)

    2010-07-01

    ... Assistant Attorney General for Administration. (a) The Assistant Attorney General for Administration is... Assistant Attorney General for Administration shall appoint a Department Security Officer and may delegate... necessary to effectively implement this part. (b) The Assistant Attorney General for Administration shall...

  11. Communication Skills in Dental Students: New Data Regarding Retention and Generalization of Training Effects.

    Science.gov (United States)

    Broder, Hillary L; Janal, Malvin; Mitnick, Danielle M; Rodriguez, Jasmine Y; Sischo, Lacey

    2015-08-01

    Previous studies have shown that a communications program using patient instructors (PIs) facilitates data-gathering and interpersonal skills of third-year dental students. The aim of this study was to address the question of whether those skills are retained into the students' fourth year and generalized from the classroom to the clinic. In the formative training phase, three cohorts of D3 students (N=1,038) at one dental school received instruction regarding effective patient-doctor communication; interviewed three PIs and received PI feedback; and participated in a reflective seminar with a behavioral science instructor. In the follow-up competency phase, fourth-year students performed two new patient interviews in the clinic that were observed and evaluated by clinical dental faculty members trained in communications. Mean scores on a standardized communications rating scale and data-gathering assessment were compared over training and follow-up sessions and between cohorts with a linear mixed model. The analysis showed that the third-year students' mean communication and data-gathering scores increased with each additional encounter with a PI (pcommunication scores were not only maintained but increased during the fourth-year follow-up competency evaluations (pcommunications curriculum, prior instruction facilitated the students' clinical communication performance at baseline (pCommunications program improved students' data-gathering and interpersonal skills. Those skills were maintained and generalized through completion of the D4 students' summative competency performance in a clinical setting.

  12. McDonald Generalized Linear Failure Rate Distribution

    Directory of Open Access Journals (Sweden)

    Ibrahim Elbatal

    2014-10-01

    Full Text Available We introduce in this paper a new six-parameters generalized version of the generalized linear failure rate (GLFR distribution which is called McDonald Generalized Linear failure rate (McGLFR distribution. The new distribution is quite flexible and can be used effectively in modeling survival data and reliability problems. It can have a constant, decreasing, increasing, and upside down bathtub-and bathtub shaped failure rate function depending on its parameters. It includes some well-known lifetime distributions as special sub-models. Some structural properties of the new distribution are studied. Moreover we discuss maximum likelihood estimation of the unknown parameters of the new model.

  13. Einstellungen von Studierenden zur Allgemeinmedizin: Einflüsse von Geschlecht, Blockpraktikum und Gesamtcurriculum [Attitudes of medical students towards general practice: Effects of gender, a general practice clerkship and a modern curriculum

    Directory of Open Access Journals (Sweden)

    Kruschinski, Carsten

    2011-02-01

    Full Text Available [english] Aims: Planning a career in general practice depends on positive attitudes towards primary care. The aim of this study was to compare attitudes of medical students of a Modern Curriculum at Hannover Medical School with those of the Traditional Curriculum before (pre and after (post a three-week clerkship in general practice. In parallel, we aimed to analyse several other variables such as age and gender, which could influence the attitudes.Methods: Prospective survey of n=287 5th-year students. Attitudes (dependent variable, Likert-scale items as well as socio-demographic characteristics (age, gender, rural/urban background, school leaving examination grades, former qualifications, experiences in general practice and career plans were requested. Attitudes were analysed separately according to these characteristics (e.g. career plans: general practitioner (GP/specialist, curriculum type and pre/post the clerkship in general practice. Bi- and multivariate statistical analysis was used including a factor analysis for grouping of the attitude items. Results: Most and remarkable differences of attitudes were seen after analysis according to gender. Women appreciated general practice more than men including a greater interest in chronic diseases, communication and psychosocial aspects. The clerkship (a total of n=165 students of the “post” survey could be matched contributed to positive attitudes of students of both gender, whereas the different curricula did not show such effects.Conclusions: Affective learning goals such as a positive attitude towards general practice have depended more on characteristics of students (gender and effects of a clerkship in general practice than on the curriculum type (modern, traditional so far. For the development of outcomes in medical education research as well as for the evolution of the Modern Curriculum such attitudes and other affective learning goals should be considered more frequently. [german

  14. Long-term effects of emissions to the sea from the offshore sector. General note; Langtidsvirkninger fra utslipp til sjoe fra offshoresektoren

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-06-01

    This general note reviews the general understanding of the long-term effects of emission to the sea from the offshore sector and the need for competence and research. During the last 20 years, considerable efforts have been made in environmental research and monitoring in the oil sector. Nevertheless, evidently more research is needed in several fields. Priority has been given to the research needed according to (1) the amount of money needed for increased knowledge about the long-term effects of emissions to the sea from the oil sector, (2) the extent of missing knowledge, (3) to what extent new knowledge would be expected to contribute to improved decisions about environmental measures, (4) the extent of potential impacts on the ecosystems in Norwegian seas and the geographical extent of a possible effect. The identified research areas are, according to priority, (1) effects in the water column of produced water, (2) sudden emissions and drilling fluid, (3) joint research and monitoring, (4) special research programmes in arctic regions, (5) emissions in progress from cuttings and long-term effects of sudden emissions in coastal zones and beach zones. Research currently in progress should be co-ordinated through a special research programme, for which there is a clear need. The funds for such a programme should come from both the industry and the authorities.

  15. Generalized operator canonical formalism and gauge invariance

    International Nuclear Information System (INIS)

    Fradkina, T.E.

    1988-01-01

    A direct proof is given in the functional representation of the invariance of the S-matrix constructed in the framework of the generalized operator canonical formalism. We find the traditional functional expression for the S-matrix (without point-splitting in the time factor) in the generalized phase space, as well as in the ghost configuration space. An explicit expression is obtained for the effective unitarizing Hamiltonian for gauge theories with constraints of arbitrary rank

  16. Effectiveness and cost-effectiveness of a proactive, goal-oriented, integrated care model in general practice for older people. A cluster randomised controlled trial: Integrated Systematic Care for older People--the ISCOPE study.

    Science.gov (United States)

    Blom, Jeanet; den Elzen, Wendy; van Houwelingen, Anne H; Heijmans, Margot; Stijnen, Theo; Van den Hout, Wilbert; Gussekloo, Jacobijn

    2016-01-01

    older people often experience complex problems. Because of multiple problems, care for older people in general practice needs to shift from a 'problem-based, disease-oriented' care aiming at improvement of outcomes per disease to a 'goal-oriented care', aiming at improvement of functioning and personal quality of life, integrating all healthcare providers. Feasibility and cost-effectiveness of this proactive and integrated way of working are not yet established. cluster randomised trial. all persons aged ≥75 in 59 general practices (30 intervention, 29 control), with a combination of problems, as identified with a structured postal questionnaire with 21 questions on four health domains. for participants with problems on ≥3 domains, general practitioners (GPs) made an integrated care plan using a functional geriatric approach. Control practices: care as usual. (i) quality of life (QoL), (ii) activities of daily living, (iii) satisfaction with delivered health care and (iv) cost-effectiveness of the intervention at 1-year follow-up. Netherlands trial register, NTR1946. of the 11,476 registered eligible older persons, 7,285 (63%) participated in the screening. One thousand nine hundred and twenty-one (26%) had problems on ≥3 health domains. For 225 randomly chosen persons, a care plan was made. No beneficial effects were found on QoL, patients' functioning or healthcare use/costs. GPs experienced better overview of the care and stability, e.g. less unexpected demands, in the care. GPs prefer proactive integrated care. 'Horizontal' care using care plans for older people with complex problems can be a valuable tool in general practice. However, no direct beneficial effect was found for older persons. © The Author 2016. Published by Oxford University Press on behalf of the British Geriatrics Society.

  17. Aerosol indirect effects -- general circulation model intercomparison and evaluation with satellite data

    Energy Technology Data Exchange (ETDEWEB)

    Quaas, Johannes; Ming, Yi; Menon, Surabi; Takemura, Toshihiko; Wang, Minghuai; Penner, Joyce E.; Gettelman, Andrew; Lohmann, Ulrike; Bellouin, Nicolas; Boucher, Olivier; Sayer, Andrew M.; Thomas, Gareth E.; McComiskey, Allison; Feingold, Graham; Hoose, Corinna; Kristjansson, Jon Egill; Liu, Xiaohong; Balkanski, Yves; Donner, Leo J.; Ginoux, Paul A.; Stier, Philip; Feichter, Johann; Sednev, Igor; Bauer, Susanne E.; Koch, Dorothy; Grainger, Roy G.; Kirkevag, Alf; Iversen, Trond; Seland, Oyvind; Easter, Richard; Ghan, Steven J.; Rasch, Philip J.; Morrison, Hugh; Lamarque, Jean-Francois; Iacono, Michael J.; Kinne, Stefan; Schulz, Michael

    2009-04-10

    Aerosol indirect effects continue to constitute one of the most important uncertainties for anthropogenic climate perturbations. Within the international AEROCOM initiative, the representation of aerosol-cloud-radiation interactions in ten different general circulation models (GCMs) is evaluated using three satellite datasets. The focus is on stratiform liquid water clouds since most GCMs do not include ice nucleation effects, and none of the model explicitly parameterizes aerosol effects on convective clouds. We compute statistical relationships between aerosol optical depth (Ta) and various cloud and radiation quantities in a manner that is consistent between the models and the satellite data. It is found that the model-simulated influence of aerosols on cloud droplet number concentration (Nd) compares relatively well to the satellite data at least over the ocean. The relationship between Ta and liquid water path is simulated much too strongly by the models. It is shown that this is partly related to the representation of the second aerosol indirect effect in terms of autoconversion. A positive relationship between total cloud fraction (fcld) and Ta as found in the satellite data is simulated by the majority of the models, albeit less strongly than that in the satellite data in most of them. In a discussion of the hypotheses proposed in the literature to explain the satellite-derived strong fcld - Ta relationship, our results indicate that none can be identified as unique explanation. Relationships similar to the ones found in satellite data between Ta and cloud top temperature or outgoing long-wave radiation (OLR) are simulated by only a few GCMs. The GCMs that simulate a negative OLR - Ta relationship show a strong positive correlation between Ta and fcld The short-wave total aerosol radiative forcing as simulated by the GCMs is strongly influenced by the simulated anthropogenic fraction of Ta, and parameterisation assumptions such as a lower bound on Nd

  18. Effect of intercostal nerve block combined with general anesthesia on the stress response in patients undergoing minimally invasive mitral valve surgery.

    Science.gov (United States)

    Zhan, Yanping; Chen, Guo; Huang, Jian; Hou, Benchao; Liu, Weicheng; Chen, Shibiao

    2017-10-01

    The aim of the present study was to investigate the effect of intercostal nerve block combined with general anesthesia on the stress response and postoperative recovery in patients undergoing minimally invasive mitral valve surgery (MIMVS). A total of 30 patients scheduled for MIMVS were randomly divided into two groups (n=15 each): Group A, which received intercostal nerve block combined with general anesthesia and group B, which received general anesthesia alone. Intercostal nerve block in group A was performed with 0.5% ropivacaine from T3 to T7 prior to anesthesia induction. In each group, general anesthesia was induced using midazolam, sufentanil, propofol and vecuronium. Central venous blood samples were collected to determine the concentrations of cortisol, glucose, interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) at the following time points: During central venous catheterization (T 1 ), 5 min prior to cardiopulmonary bypass (T 2 ), perioperative (T 3 ) and 24 h following surgery (T 4 ). Clinical data, including parameters of opioid (sufentanil) consumption, time of mechanical ventilation, duration of intensive care unit (ICU) stay, visual analog scale scores and any complications arising from intercostal nerve block, were recorded. Levels of cortisol, glucose, IL-6 and TNF-α in group A were significantly lower than those in group B at T 2 (all Pblock combined with general anesthesia may inhibit the stress response to MIMVS. Additionally, intercostal nerve block combined with general anesthesia may significantly reduce sufentanil consumption (Pblock combined with general anesthesia conforms to the concept of rapid rehabilitation surgery and may be suitable for clinical practice.

  19. Toward a general theory of momentum-like effects.

    Science.gov (United States)

    Hubbard, Timothy L

    2017-08-01

    The future actions, behaviors, and outcomes of objects, individuals, and processes can often be anticipated, and some of these anticipations have been hypothesized to result from momentum-like effects. Five types of momentum-like effects (representational momentum, operational momentum, attentional momentum, behavioral momentum, psychological momentum) are briefly described. Potential similarities involving properties of momentum-like effects (continuation, coherence, role of chance or guessing, role of sensory processing, imperviousness to practice or error feedback, shifts in memory for position, effects of changes in velocity, rapid occurrence, effects of retention interval, attachment to an object rather than an abstract frame of reference, nonrigid transformation) are described, and potential constraints on a future theory of momentum-like effects (dynamic representation, nature of extrapolation, sensitivity to environmental contingencies, bridging gaps between stimulus and response, increasing adaptiveness to the environment, serving as a heuristic for perception and action, insensitivity to stimulus format, importance of subjective consequences, role of knowledge and belief, automaticity of occurrence, properties of functional architecture) are discussed. The similarity and ubiquity of momentum-like effects suggests such effects might result from a single or small number of mechanisms that operate over different dimensions, modalities, and time-scales and provide a fundamental adaptation for perception and action. Copyright © 2017. Published by Elsevier B.V.

  20. Generalized uncertainty principle and quantum gravity phenomenology

    Science.gov (United States)

    Bosso, Pasquale

    The fundamental physical description of Nature is based on two mutually incompatible theories: Quantum Mechanics and General Relativity. Their unification in a theory of Quantum Gravity (QG) remains one of the main challenges of theoretical physics. Quantum Gravity Phenomenology (QGP) studies QG effects in low-energy systems. The basis of one such phenomenological model is the Generalized Uncertainty Principle (GUP), which is a modified Heisenberg uncertainty relation and predicts a deformed canonical commutator. In this thesis, we compute Planck-scale corrections to angular momentum eigenvalues, the hydrogen atom spectrum, the Stern-Gerlach experiment, and the Clebsch-Gordan coefficients. We then rigorously analyze the GUP-perturbed harmonic oscillator and study new coherent and squeezed states. Furthermore, we introduce a scheme for increasing the sensitivity of optomechanical experiments for testing QG effects. Finally, we suggest future projects that may potentially test QG effects in the laboratory.

  1. Generalized Einstein-Aether theories and the Solar System

    International Nuclear Information System (INIS)

    Bonvin, Camille; Durrer, Ruth; Ferreira, Pedro G.; Zlosnik, Tom G.; Starkman, Glenn

    2008-01-01

    It has been shown that generalized Einstein-Aether theories may lead to significant modifications to the nonrelativistic limit of the Einstein equations. In this paper we study the effect of a general class of such theories on the Solar System. We consider corrections to the gravitational potential in negative and positive powers of distance from the source. Using measurements of the perihelion shift of Mercury and time delay of radar signals to Cassini, we place constraints on these corrections. We find that a subclass of generalized Einstein-Aether theories is compatible with these constraints

  2. The effect of music therapy compared with general recreational activities in reducing agitation in people with dementia: a randomised controlled trial

    NARCIS (Netherlands)

    Vink, A.C.; Zuidersma, M.; Boersma, F.; Jonge, P. de; Zuidema, S.U.; Slaets, J.P.

    2013-01-01

    OBJECTIVE: This study aimed to compare the effects of music therapy with general recreational day activities in reducing agitation in people with dementia, residing in nursing home facilities. METHODS: In a randomised controlled design, residents with dementia (n = 94) were allocated to either music

  3. The effect of music therapy compared with general recreational activities in reducing agitation in people with dementia : a randomised controlled trial

    NARCIS (Netherlands)

    Vink, A. C.; Zuidersma, M.; Boersma, F.; de Jonge, P.; Zuidema, S. U.; Slaets, J. P. J.

    2013-01-01

    Objective This study aimed to compare the effects of music therapy with general recreational day activities in reducing agitation in people with dementia, residing in nursing home facilities. Methods In a randomised controlled design, residents with dementia (n=94) were allocated to either music

  4. Quantum-mechanical generalization of the Biot-Savart law

    International Nuclear Information System (INIS)

    Fassio-Canuto, L.

    1978-01-01

    The complex geometrical considerations involved in deriving the magnetic field due to a current of assigned geometry can be considerably simplified and, therefore, generalized if one employs the field-theoretical relation between the field Asub(μ) and the current jsub(μ). In the general case of a current with helicoidal structure, the magnetic field can be found for any point of space. The particular cases of the loop, the solenoid and the straight wire are then easily derived. The rationale for wanting to generalize the classical Biot-Savart law to include quantum-mechanical effects is discussed in the light of a more general program intended to study the origin of magnetic fields in collapsed objects. (author)

  5. Generality of the Hartman and Fletcher effect for the mean tunneling time in nonrelativistic particle and photon tunnelling without absorption and dissipation

    International Nuclear Information System (INIS)

    Jakiel, J.; Olkhovsky, V.S.

    1998-01-01

    It is known that, under certain conditions, the tunnelling time becomes independent of barrier width (the Hartman and Fletcher effect). Here, the generality of this effect is shown for mean tunnelling times in all known nonrelativistic approaches, in the cases of rectangular potential barriers without absorption and dissipation. On the base of this effect and the reshaping phenomenon, taking the analogy between nonrelativistic-particle and photon tunnelling into, account, one can self-consistently explain the observed superluminal effective (group) velocities in various photon tunnelling experiments without violation of the Einstein causality

  6. Butorphanol suppresses fentanyl-induced cough during general anesthesia induction

    OpenAIRE

    Cheng, Xiao-Yan; Lun, Xiao-Qin; Li, Hong-Bo; Zhang, Zhi-Jie

    2016-01-01

    Abstract Fentanyl-induced cough (FIC) is unwanted in the patients requiring stable induction of general anesthesia. This study was designed to evaluate the suppressive effects of butorphanol pretreatment on the incidence and severity of FIC during the induction of general anesthesia. A total of 315 patients of American Society of Anesthesiologists physical status I and II, scheduled for elective surgery under general anesthesia were randomized into 3 equally sized groups (n = 0105). Two minut...

  7. Partisan strength, political trust and generalized trust in the United States: An analysis of the General Social Survey, 1972-2014.

    Science.gov (United States)

    Hooghe, Marc; Oser, Jennifer

    2017-11-01

    The literature on political parties suggests that strong partisan identities are associated with citizens' effective interaction with the political system, and with higher levels of political trust. Traditionally, party identity therefore is seen as a mechanism that allows for political integration. Simultaneously, however, political parties have gained recent attention for their role in promoting societal polarization by reinforcing competing and even antagonistic group identities. This article uses General Social Survey data from 1972 - 2014 to investigate the relationship between partisan strength and both political and generalized trust. The findings show that increases in partisan strength are positively related to political trust, but negatively related to generalized trust. This suggests that while partisan strength is indeed an important linkage mechanism for the political system, it is also associated with a tendency toward social polarization, and this corrosive effect thus far has not gained sufficient attention in literature on party identity. Copyright © 2017 Elsevier Inc. All rights reserved.

  8. General anesthesia in cardiac surgery: a review of drugs and practices.

    Science.gov (United States)

    Alwardt, Cory M; Redford, Daniel; Larson, Douglas F

    2005-06-01

    General anesthesia is defined as complete anesthesia affecting the entire body with loss of consciousness, analgesia, amnesia, and muscle relaxation. There is a wide spectrum of agents able to partially or completely induce general anesthesia. Presently, there is not a single universally accepted technique for anesthetic management during cardiac surgery. Instead, the drugs and combinations of drugs used are derived from the pathophysiologic state of the patient and individual preference and experience of the anesthesiologist. According to the definition of general anesthesia, current practices consist of four main components: hypnosis, analgesia, amnesia, and muscle relaxation. Although many of the agents highlighted in this review are capable of producing more than one of these effects, it is logical that drugs producing these effects are given in combination to achieve the most beneficial effect. This review features a discussion of currently used anesthetic drugs and clinical practices of general anesthesia during cardiac surgery. The information in this particular review is derived from textbooks, current literature, and personal experience, and is designed as a general overview of anesthesia during cardiac surgery.

  9. Interaction Effects of Season of Birth and Cytokine Genes on Schizotypal Traits in the General Population

    Directory of Open Access Journals (Sweden)

    Margarita V. Alfimova

    2017-01-01

    Full Text Available Literature suggests that the effect of winter birth on vulnerability to schizophrenia might be mediated by increased expression of proinflammatory cytokines due to prenatal infection and its inadequate regulation by anti-inflammatory factors. As the response of the immune system depends on genotype, this study assessed the interaction effects of cytokine genes and season of birth (SOB on schizotypy measured with the Schizotypal Personality Questionnaire (SPQ-74. We searched for associations of IL1B rs16944, IL4 rs2243250, and IL-1RN VNTR polymorphisms, SOB, and their interactions with the SPQ-74 total score in a sample of 278 healthy individuals. A significant effect of the IL4 X SOB interaction was found, p=0.007 and η2=0.028. We confirmed this effect using an extended sample of 373 individuals. Homozygotes CC born in winter showed the highest SPQ total score and differed significantly from winter-born T allele carriers, p=0.049. This difference was demonstrated for cognitive-perceptual and disorganized but not interpersonal dimensions. The findings are consistent with the hypothesis that the cytokine genes by SOB interaction can influence variability of schizotypal traits in the general population. The IL4 T allele appeared to have a protective effect against the development of positive and disorganized schizotypal traits in winter-born individuals.

  10. Interaction Effects of Season of Birth and Cytokine Genes on Schizotypal Traits in the General Population.

    Science.gov (United States)

    Alfimova, Margarita V; Korovaitseva, Galina I; Lezheiko, Tatyana V; Golimbet, Vera E

    2017-01-01

    Literature suggests that the effect of winter birth on vulnerability to schizophrenia might be mediated by increased expression of proinflammatory cytokines due to prenatal infection and its inadequate regulation by anti-inflammatory factors. As the response of the immune system depends on genotype, this study assessed the interaction effects of cytokine genes and season of birth (SOB) on schizotypy measured with the Schizotypal Personality Questionnaire (SPQ-74). We searched for associations of IL1B rs16944, IL4 rs2243250, and IL-1RN VNTR polymorphisms, SOB, and their interactions with the SPQ-74 total score in a sample of 278 healthy individuals. A significant effect of the IL4 X SOB interaction was found, p = 0.007 and η 2 = 0.028. We confirmed this effect using an extended sample of 373 individuals. Homozygotes CC born in winter showed the highest SPQ total score and differed significantly from winter-born T allele carriers, p = 0.049. This difference was demonstrated for cognitive-perceptual and disorganized but not interpersonal dimensions. The findings are consistent with the hypothesis that the cytokine genes by SOB interaction can influence variability of schizotypal traits in the general population. The IL4 T allele appeared to have a protective effect against the development of positive and disorganized schizotypal traits in winter-born individuals.

  11. Generalized Probability Functions

    Directory of Open Access Journals (Sweden)

    Alexandre Souto Martinez

    2009-01-01

    Full Text Available From the integration of nonsymmetrical hyperboles, a one-parameter generalization of the logarithmic function is obtained. Inverting this function, one obtains the generalized exponential function. Motivated by the mathematical curiosity, we show that these generalized functions are suitable to generalize some probability density functions (pdfs. A very reliable rank distribution can be conveniently described by the generalized exponential function. Finally, we turn the attention to the generalization of one- and two-tail stretched exponential functions. We obtain, as particular cases, the generalized error function, the Zipf-Mandelbrot pdf, the generalized Gaussian and Laplace pdf. Their cumulative functions and moments were also obtained analytically.

  12. Effect of Intravenous Infusion of Lidocaine on Pain Reduction after Cesarean Section under General Anesthesia

    Directory of Open Access Journals (Sweden)

    Anahita Hirmanpour

    2018-01-01

    Full Text Available Background: The present study was conducted to evaluate the effect of Lidocaine on pain reduction during and ileus and the need for opioids after caesarean section. Methods: For this randomized double-blind controlled clinical trial, 40 ASA I, II pregnant women who were candidates for caesarean section with general anesthesia, were randomly allocated into two groups of Lidocaine receivers and placebo using randomized block design; the Lidocaine group received 1.5 mg/kg of Lidocaine right before the surgery and then its infusion with a dose of 2 mg/kg.h until the end of the surgery and the placebo group received normal saline with the same volume and application. Patients’ pain intensity was measured using numerical rating scale (NRS, 0 (entering the recovery, 0.5, 1, 4, 12 and 24 hours after the surgery. Results: Lidocaine decreased the systolic and diastolic pressures of the patients only during the first minute after intubation, decreased the mean of arterial blood pressure at the 10th minute after intubation and 40th minute after surgery, and also decreased the mean of patients’ pain intensity, Diclofenac and Pethidine consumption, side effects (nausea and vomiting and reduced the time interval before the first time of tolerating oral liquids; but it had effect on infants’ Apgar score 1 and 5 minutes after delivery. Conclusions: Lidocaine was definitely effective on reducing the intensity of pain, opioid and non-steroidal anti-inflammatory drugs consumption and ileus after surgery with the least occurrence of side effects for mothers and infants.

  13. Effect of Intravenous Infusion of Lidocaine on Pain Reduction after Cesarean Section under General Anesthesia

    Directory of Open Access Journals (Sweden)

    Anahita Hirmanpour

    2018-01-01

    Full Text Available Background: The present study was conducted to evaluate the effect of Lidocaine on pain reduction during and ileus and the need for opioids after caesarean section.Methods: For this randomized double-blind controlled clinical trial, 40 ASA I, II pregnant women who were candidates for caesarean section with general anesthesia, were randomly allocated into two groups of Lidocaine receivers and placebo using randomized block design; the Lidocaine group received 1.5 mg/kg of Lidocaine right before the surgery and then its infusion with a dose of 2 mg/kg.h until the end of the surgery and the placebo group received normal saline with the same volume and application. Patients’ pain intensity was measured using numerical rating scale (NRS, 0 (entering the recovery, 0.5, 1, 4, 12 and 24 hours after the surgery.Results: Lidocaine decreased the systolic and diastolic pressures of the patients only during the first minute after intubation, decreased the mean of arterial blood pressure at the 10th minute after intubation and 40th minute after surgery, and also decreased the mean of patients’ pain intensity, Diclofenac and Pethidine consumption, side effects (nausea and vomiting and reduced the time interval before the first time of tolerating oral liquids; but it had effect on infants’ Apgar score 1 and 5 minutes after delivery.Conclusions: Lidocaine was definitely effective on reducing the intensity of pain, opioid and non-steroidal anti-inflammatory drugs consumption and ileus after surgery with the least occurrence of side effects for mothers and infants.

  14. A Comparison of the Effects of Pilates and McKenzie Training on Pain and General Health in Men with Chronic Low Back Pain: A Randomized Trial.

    Science.gov (United States)

    Hasanpour-Dehkordi, Ali; Dehghani, Arman; Solati, Kamal

    2017-01-01

    Today, chronic low back pain is one of the special challenges in healthcare. There is no unique approach to treat chronic low back pain. A variety of methods are used for the treatment of low back pain, but the effects of these methods have not yet been investigated adequately. The aim of this study was to compare the effects of Pilates and McKenzie training on pain and general health of men with chronic low back pain. Thirty-six patients with chronic low back pain were chosen voluntarily and assigned to three groups of 12 each: McKenzie group, Pilates group, and control group. The Pilates group participated in 1-h exercise sessions, three sessions a week for 6 weeks. McKenzie group performed workouts 1 h a day for 20 days. The control group underwent no treatment. The general health of all participants was measured by the General Health Questionnaire 28 and pain by the McGill Pain Questionnaire. After therapeutic exercises, there was no significant difference between Pilates and McKenzie groups in pain relief ( P = 0.327). Neither of the two methods was superior over the other for pain relief. However, there was a significant difference in general health indexes between Pilates and McKenzie groups. Pilates and McKenzie training reduced pain in patients with chronic low back pain, but the Pilates training was more effective to improve general health.

  15. Generalized geometry and partial supersymmetry breaking

    Energy Technology Data Exchange (ETDEWEB)

    Triendl, Hagen Mathias

    2010-08-15

    This thesis consists of two parts. In the first part we use the formalism of (exceptional) generalized geometry to derive the scalar field space of SU(2) x SU(2)-structure compactifications. We show that in contrast to SU(3) x SU(3) structures, there is no dynamical SU(2) x SU(2) structure interpolating between an SU(2) structure and an identity structure. Furthermore, we derive the scalar manifold of the low-energy effective action for consistent Kaluza-Klein truncations as expected from N = 4 supergravity. In the second part we then determine the general conditions for the existence of stable Minkowski and AdS N = 1 vacua in spontaneously broken gauged N = 2 supergravities and construct the general solution under the assumption that two appropriate commuting isometries exist in the hypermultiplet sector. Furthermore, we derive the low-energy effective action below the scale of partial supersymmetry breaking and show that it satisfies the constraints of N = 1 supergravity. We then apply the discussion to special quaternionic-Kaehler geometries which appear in the low-energy limit of SU(3) x SU(3)-structure compactifications and construct Killing vectors with the right properties. Finally we discuss the string theory realizations for these solutions. (orig.)

  16. Generalized geometry and partial supersymmetry breaking

    International Nuclear Information System (INIS)

    Triendl, Hagen Mathias

    2010-08-01

    This thesis consists of two parts. In the first part we use the formalism of (exceptional) generalized geometry to derive the scalar field space of SU(2) x SU(2)-structure compactifications. We show that in contrast to SU(3) x SU(3) structures, there is no dynamical SU(2) x SU(2) structure interpolating between an SU(2) structure and an identity structure. Furthermore, we derive the scalar manifold of the low-energy effective action for consistent Kaluza-Klein truncations as expected from N = 4 supergravity. In the second part we then determine the general conditions for the existence of stable Minkowski and AdS N = 1 vacua in spontaneously broken gauged N = 2 supergravities and construct the general solution under the assumption that two appropriate commuting isometries exist in the hypermultiplet sector. Furthermore, we derive the low-energy effective action below the scale of partial supersymmetry breaking and show that it satisfies the constraints of N = 1 supergravity. We then apply the discussion to special quaternionic-Kaehler geometries which appear in the low-energy limit of SU(3) x SU(3)-structure compactifications and construct Killing vectors with the right properties. Finally we discuss the string theory realizations for these solutions. (orig.)

  17. Generalized Cartan Calculus in general dimension

    Science.gov (United States)

    Wang, Yi-Nan

    2015-07-01

    We develop the generalized Cartan Calculus for the groups and SO(5 , 5). They are the underlying algebraic structures of d = 9 , 7 , 6 exceptional field theory, respectively. These algebraic identities are needed for the "tensor hierarchy" structure in exceptional field theory. The validity of Poincaré lemmas in this new differential geometry is also discussed. Finally we explore some possible extension of the generalized Cartan calculus beyond the exceptional series.

  18. Statement of the Director General to the forty-second regular session of the General Conference of the International Atomic Energy Agency

    International Nuclear Information System (INIS)

    1998-01-01

    In his Statement on the forty-second regular session of the General Conference of the IAEA, the Director General of the Agency highlighted the role of the IAEA in four areas: nuclear power and the fuel cycle, nuclear and radiation safety, nuclear verification and the security of material, and transfer of technology. The final part of the Statement is devoted to the process of programme and management review initiated by the Director General to ensure that the Agency maintains and enhances its record as an effective and efficient organization

  19. Effect of Governance Indicators on Under-Five Mortality in OECD Nations: Generalized Method of Moments.

    Science.gov (United States)

    Emamgholipour, Sara; Asemane, Zahra

    2016-01-01

    Today, it is recognized that factors other than health services are involved in health improvement and decreased inequality so identifying them is the main concern of policy makers and health authorities. The aim of this study was to investigate the effect of governance indicators on health outcomes. A panel data study was conducted to investigate the effect of governance indicators on child mortality rate in 27 OECD countries from 1996 to 2012 using the Generalized Method of Moments (GMM) model and EVIEWS.8 software. According to the results obtained, under-five mortality rate was significantly related to all of the research variables (p corruption and rule of law indicators decreased child mortality rate by 0.05 and 0.08%, respectively. Furthermore, 1% increase in public health expenditure per capita resulted in a 0.03% decrease in under-five mortality rate. The results of the study suggest that considering control variables, including GDP per capita, public health expenditure per capita, total fertility rate, and improvement of governance indicators (control of corruption and rule of law) would decrease the child mortality rate.

  20. The Generalized Quantum Statistics

    OpenAIRE

    Hwang, WonYoung; Ji, Jeong-Young; Hong, Jongbae

    1999-01-01

    The concept of wavefunction reduction should be introduced to standard quantum mechanics in any physical processes where effective reduction of wavefunction occurs, as well as in the measurement processes. When the overlap is negligible, each particle obey Maxwell-Boltzmann statistics even if the particles are in principle described by totally symmetrized wavefunction [P.R.Holland, The Quantum Theory of Motion, Cambridge Unversity Press, 1993, p293]. We generalize the conjecture. That is, par...

  1. Study on the estimation of probabilistic effective dose. Committed effective dose from intake of marine products using Oceanic General Circulation Model

    International Nuclear Information System (INIS)

    Nakano, Masanao

    2007-01-01

    The worldwide environmental protection is required by the public. A long-term environmental assessment from nuclear fuel cycle facilities to the aquatic environment also becomes more important to utilize nuclear energy more efficiently. Evaluation of long-term risk including not only in Japan but also in neighboring countries is considered to be necessary in order to develop nuclear power industry. The author successfully simulated the distribution of radionuclides in seawater and seabed sediment produced by atmospheric nuclear tests using LAMER (Long-term Assessment ModEl for Radioactivity in the oceans). A part of the LAMER calculated the advection- diffusion-scavenging processes for radionuclides in the oceans and the Japan Sea in cooperate with Oceanic General Circulation Model (OGCM) and was validated. The author is challenging to calculate probabilistic effective dose suggested by ICRP from intake of marine products due to atmospheric nuclear tests using the Monte Carlo method in the other part of LAMER. Depending on the deviation of each parameter, the 95th percentile of the probabilistic effective dose was calculated about half of the 95th percentile of the deterministic effective dose in proforma calculation. The probabilistic assessment gives realistic value for the dose assessment of a nuclear fuel cycle facility. (author)

  2. An Outcomes Study on the Effects of the Singapore General Hospital Burns Protocol.

    Science.gov (United States)

    Liang, Weihao; Kok, Yee Onn; Tan, Bien Keem; Chong, Si Jack

    2018-01-01

    The Singapore General Hospital Burns Protocol was implemented in May 2014 to standardize treatment for all burns patients, incorporate new techniques and materials, and streamline the processes and workflow of burns management. This study aims to analyze the effects of the Burns Protocol 2 years after its implementation. Using a REDCap electronic database, all burns patients admitted from May 2013 to April 2016 were included in the study. The historical preimplementation control group composed of patients admitted from May 2013 to April 2014 (n = 96). The postimplementation prospective study cohort consisted of patients admitted from May 2014 to April 2016 (n = 243). Details of the patients collected included age, sex, comorbidities, total body surface area (TBSA) burns, time until surgery, number of surgeries, number of positive tissue and blood cultures, and length of hospital stay. There was no statistically significant difference in the demographics of both groups. The study group had a statistically significant shorter time to surgery compared with the control group (20.8 vs 38.1, P burns, was statistically significant (number of surgeries/TBSA, 0.324 vs 0.506; P = 0.0499). The study group also had significantly shorter length of stay (12.5 vs 16.8, P = 0.0273), a shorter length of stay/TBSA burns (0.874 vs 1.342, P = 0.0101), and fewer positive tissue cultures (0.6 vs 1.3, P = 0.0003). The study group also trended toward fewer positive blood culture results (0.09 vs 0.35, P = 0.0593), although the difference was just shy of statistical significance. The new Singapore General Hospital Burns Protocol had revolutionized Singapore burns care by introducing a streamlined, multidisciplinary burns management, resulting in improved patient outcomes, lowered health care costs, and improved system resource use.

  3. Effects of detector–source distance and detector bias voltage variations on time resolution of general purpose plastic scintillation detectors

    International Nuclear Information System (INIS)

    Ermis, E.E.; Celiktas, C.

    2012-01-01

    Effects of source-detector distance and the detector bias voltage variations on time resolution of a general purpose plastic scintillation detector such as BC400 were investigated. 133 Ba and 207 Bi calibration sources with and without collimator were used in the present work. Optimum source-detector distance and bias voltage values were determined for the best time resolution by using leading edge timing method. Effect of the collimator usage on time resolution was also investigated. - Highlights: ► Effect of the source-detector distance on time spectra was investigated. ► Effect of the detector bias voltage variations on time spectra was examined. ► Optimum detector–source distance was determined for the best time resolution. ► Optimum detector bias voltage was determined for the best time resolution. ► 133 Ba and 207 Bi radioisotopes were used.

  4. Mental Health of General Practitioners in Emergency Wards

    Directory of Open Access Journals (Sweden)

    Sepehrmanesh Z.1 PhD,

    2015-01-01

    Full Text Available Aims General practitioners have an essential role in patient care and are exposed to high levels of job stress. General practitioners’ mental health has effects on their functional abilities and medical managements.This study was carried out to evaluate the mental health of general practitioners in emergency wards in KashanUniversity of Medical Sciences, Iran. Materials & Methods In this cross-sectional study, all of General practitioners in emergency wards (n=87 were studied. The survey instruments includedtwo questionnaires: 1-demographic variables and 2- General Health Questionnaire (GHQ-28. Data were analyzed using SPSS 16 software and Chi square, Fisher exactand Mann-Whitney statistical tests. Findings The mean age of general practitioners was 36.11±5.67 years; 89.7% of them were married; 60.3% were male. 41% of the total general practitioners had mental health problems. The mean score of GHQ was 22.56±9.24. There were significant relationships between mental health and each age, employment situation, and number of children (p0.05. Conclusion The majority of employed general practitioners in emergency rooms do not have proper mental health statuses.

  5. General Editorial

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. General Editorial. Articles in Resonance – Journal of Science Education. Volume 19 Issue 1 January 2014 pp 1-2 General Editorial. General Editorial on Publication Ethics · R Ramaswamy · More Details Fulltext PDF. Volume 19 Issue 1 January 2014 pp 3-3 ...

  6. Measuring the effects of acupuncture and homoeopathy in general practice: An uncontrolled prospective documentation approach

    Directory of Open Access Journals (Sweden)

    Walach Harald

    2004-03-01

    Full Text Available Abstract Background Despite the increasing demand for acupuncture and homoeopathy in Germany, little is known about the effects of these treatments in routine care. We set up a pragmatic documentation study in general practice funded within the scope of project launched by a German health insurer. Patients were followed-up for up to four years. Methods The aim of the project was to study the effects and benefits of acupuncture and/or homoeopathy, and to assess patient satisfaction within a prospective documentation of over 5000 acupuncture and over 900 homoeopathy patients. As data sources, we used the documentation made available by therapists on every individual visit and a standardised quality-of-life questionnaire (MOS SF-36; these were complemented by questions concerning the patient's medical history and by questions on patient satisfaction. The health insurer provided us with data on work absenteeism. Results Descriptive analyses of the main outcomes showed benefit of treatment with middle to large-sized effects for the quality of life questionnaire SF-36 and about 1 point improvement on a rating scale of effects, given by doctors. Data on the treatment and the patients' and physicians' background suggests chronically ill patients treated by fairly regular schemes. Conclusion Since the results showed evidence of a subjective benefit for patients from acupuncture and homoeopathy, this may account for the increase in demand for these treatments especially when patients are chronically ill and unsatisfied with the conventional treatment given previously.

  7. Comparison of the effects of sedation and general anesthesia in surgically assisted rapid palatal expansion.

    Science.gov (United States)

    Satilmis, Tulin; Ugurlu, Faysal; Garip, Hasan; Sener, Bedrettin C; Goker, Kamil

    2011-06-01

    To compare the effects of sedation and general anesthesia for surgically assisted rapid palatal expansion (SARPE). This randomized prospective study included 30 patients who were scheduled for SARPE, and was performed between January 2008 to February 2010 in the Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Marmara University, Istanbul, Turkey. Patients were allocated into Group S - midazolam + fentanyl sedation (n=15), and Group G - general anesthesia (n=15). Hemodynamic parameters, duration of anesthesia, surgery, recovery time, time to discharge, visual analogue scale (VAS) pain scores at 30 minutes (min), one hour (hr), 4 hours, 12 hours, and 24 hours, first consumption of analgesic time, total amount of consumption of analgesics, patient and surgeon satisfaction, nausea, and vomiting were recorded. Analgesic time was significantly longer in Group S (p=0.008), and total analgesic consumption was significantly lower in Group S than in Group G (p=0.031). Patient satisfaction was statistically higher in Group S (p=0.035). At 30 min, one hr, and 12 hrs, VAS satisfaction scores in Group S were statistically lower than those in Group G, and at 4 hrs and 24 hrs there was no statistical difference in VAS scores for both groups. The use of sedation for outpatient SARPE resulted in lower pain scores at discharge, lower analgesic consumption, and greater patient satisfaction.

  8. Effect of generalized joint hypermobility on knee function and muscle activation in children and adults

    DEFF Research Database (Denmark)

    Jensen, Bente Rona; Olesen, Annesofie T.; Pedersen, Mogens Theisen

    2013-01-01

    Introduction: We investigated muscle activation strategy and performance of knee extensor and flexor muscles in children and adults with generalized joint hypermobility (GJH) and compared them with controls. Methods: Muscle activation, torque steadiness, electromechanical delay, and muscle strength...... were evaluated in 39 children and 36 adults during isometric knee extension and flexion. Subjects performed isometric maximum contractions, submaximal contractions at 25% maximum voluntary contraction (MVC), and explosive contractions. Results: Agonist activation was reduced, and coactivation ratio...... was greater in GJH during knee flexion compared with controls. Torque steadiness was impaired in adults with GJH during knee flexion. No effect of GJH was found on muscle strength or electromechanical delay. Correlation analysis revealed an association between GJH severity and function in adults. Conclusions...

  9. General versus program-specific welfare chauvinism

    DEFF Research Database (Denmark)

    Larsen, Christian Albrekt

    2018-01-01

    similarity across programs. The Danish welfare chauvinist attitudes are in general fuelled by lack of shared identity with migrants and sociotropic concerns about the economic burden of migration. The article finds little evidence of narrow self-interest effects; with a notable exception of disability...

  10. Striving for work-life balance: effect of marriage and children on the experience of 4402 US general surgery residents.

    Science.gov (United States)

    Sullivan, Michael C; Yeo, Heather; Roman, Sanziana A; Bell, Richard H; Sosa, Julie A

    2013-03-01

    To determine how marital status and having children impact US general surgical residents' attitudes toward training and personal life. There is a paucity of research describing how family and children affect the experience of general surgery residents. Cross-sectional survey involving all US categorical general surgery residents. Responses were evaluated by resident/program characteristics. Statistical analysis included the χ test and hierarchical logistic regression modeling. A total of 4402 residents were included (82.4% response rate) and categorized as married, single, or other (separated/divorced/widowed). Men were more likely to be married (57.8% vs 37.9%, P work (P work (P work hours caused strain on family life (P work (P = 0.001), were happy at work (P = 0.001), and reported a good program fit (P = 0.034), but had strain on family life (P work [odds ratio (OR): 1.22, P = 0.035], yet feeling that work caused family strain (OR: 1.66, P work (OR: 0.81, P = 0.007). Residents who were married or parents reported greater satisfaction and work-life conflict. The complex effects of family on surgical residents should inform programs to target support mechanisms for their trainees.

  11. The Confrontation between General Relativity and Experiment

    Directory of Open Access Journals (Sweden)

    Will Clifford

    2001-01-01

    Full Text Available The status of experimental tests of general relativity and of theoretical frameworks for analysing them are reviewed. Einstein's equivalence principle (EEP is well supported by experiments such as the Eötvös experiment, tests of special relativity, and the gravitational redshift experiment. Future tests of EEP and of the inverse square law will search for new interactions arising from unification or quantum gravity. Tests of general relativity at the post-Newtonian level have reached high precision, including the light deflection, the Shapiro time delay, the perihelion advance of Mercury, and the Nordtvedt effect in lunar motion. Gravitational wave damping has been detected in an amount that agrees with general relativity to half a percent using the Hulse-Taylor binary pulsar, and new binary pulsar systems may yield further improvements.When direct observation of gravitational radiation from astrophysical sources begins, new tests of general relativity will be possible.

  12. Ecological optimization for generalized irreversible Carnot refrigerators

    International Nuclear Information System (INIS)

    Chen Lingen; Zhu Xiaoqin; Sun Fengrui; Wu Chih

    2005-01-01

    The optimal ecological performance of a Newton's law generalized irreversible Carnot refrigerator with the losses of heat resistance, heat leakage and internal irreversibility is derived by taking an ecological optimization criterion as the objective, which consists of maximizing a function representing the best compromise between the exergy output rate and exergy loss rate (entropy production rate) of the refrigerator. Numerical examples are given to show the effects of heat leakage and internal irreversibility on the optimal performance of generalized irreversible refrigerators

  13. Disaster Managers’ Perception of Effective Visual Risk Communication for General Public

    NARCIS (Netherlands)

    Charriere, M.K.M.; Bogaard, T.A.; Mostert, E.

    2012-01-01

    Risk communication is one of the measures that should be implemented to increase the awareness and preparedness of the general public in order to attain disaster risk reduction. Among the various forms that can be used in communication campaigns, visualizations are appropriate to disseminate

  14. Generalized convexity, generalized monotonicity recent results

    CERN Document Server

    Martinez-Legaz, Juan-Enrique; Volle, Michel

    1998-01-01

    A function is convex if its epigraph is convex. This geometrical structure has very strong implications in terms of continuity and differentiability. Separation theorems lead to optimality conditions and duality for convex problems. A function is quasiconvex if its lower level sets are convex. Here again, the geo­ metrical structure of the level sets implies some continuity and differentiability properties for quasiconvex functions. Optimality conditions and duality can be derived for optimization problems involving such functions as well. Over a period of about fifty years, quasiconvex and other generalized convex functions have been considered in a variety of fields including economies, man­ agement science, engineering, probability and applied sciences in accordance with the need of particular applications. During the last twenty-five years, an increase of research activities in this field has been witnessed. More recently generalized monotonicity of maps has been studied. It relates to generalized conve...

  15. Renormalization and effective actions for general relativity

    International Nuclear Information System (INIS)

    Neugebohrn, F.

    2007-05-01

    Quantum gravity is analyzed from the viewpoint of the renormalization group. The analysis is based on methods introduced by J. Polchinski concerning the perturbative renormalization with flow equations. In the first part of this work, the program of renormalization with flow equations is reviewed and then extended to effective field theories that have a finite UV cutoff. This is done for a scalar field theory by imposing additional renormalization conditions for some of the nonrenormalizable couplings. It turns out that one so obtains a statement on the predictivity of the effective theory at scales far below the UV cutoff. In particular, nonrenormalizable theories can be treated without problems in the proposed framework. In the second part, the standard covariant BRS quantization program for Euclidean Einstein gravity is applied. A momentum cutoff regularization is imposed and the resulting violation of the Slavnov-Taylor identities is discussed. Deriving Polchinski's renormalization group equation for Euclidean quantum gravity, the predictivity of effective quantum gravity at scales far below the Planck scale is investigated with flow equations. A fine-tuning procedure for restoring the violated Slavnov-Taylor identities is proposed and it is argued that in the effective quantum gravity context, the restoration will only be accomplished with finite accuracy. Finally, the no-cutoff limit of Euclidean quantum gravity is analyzed from the viewpoint of the Polchinski method. It is speculated whether a limit with nonvanishing gravitational constant might exist where the latter would ultimatively be determined by the cosmological constant and the masses of the elementary particles. (orig.)

  16. Renormalization and effective actions for general relativity

    Energy Technology Data Exchange (ETDEWEB)

    Neugebohrn, F.

    2007-05-15

    Quantum gravity is analyzed from the viewpoint of the renormalization group. The analysis is based on methods introduced by J. Polchinski concerning the perturbative renormalization with flow equations. In the first part of this work, the program of renormalization with flow equations is reviewed and then extended to effective field theories that have a finite UV cutoff. This is done for a scalar field theory by imposing additional renormalization conditions for some of the nonrenormalizable couplings. It turns out that one so obtains a statement on the predictivity of the effective theory at scales far below the UV cutoff. In particular, nonrenormalizable theories can be treated without problems in the proposed framework. In the second part, the standard covariant BRS quantization program for Euclidean Einstein gravity is applied. A momentum cutoff regularization is imposed and the resulting violation of the Slavnov-Taylor identities is discussed. Deriving Polchinski's renormalization group equation for Euclidean quantum gravity, the predictivity of effective quantum gravity at scales far below the Planck scale is investigated with flow equations. A fine-tuning procedure for restoring the violated Slavnov-Taylor identities is proposed and it is argued that in the effective quantum gravity context, the restoration will only be accomplished with finite accuracy. Finally, the no-cutoff limit of Euclidean quantum gravity is analyzed from the viewpoint of the Polchinski method. It is speculated whether a limit with nonvanishing gravitational constant might exist where the latter would ultimatively be determined by the cosmological constant and the masses of the elementary particles. (orig.)

  17. 49 CFR 215.107 - Defective plain bearing box: General.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Defective plain bearing box: General. 215.107... Suspension System § 215.107 Defective plain bearing box: General. A railroad may not place or continue in... the bearing; or (2) Have a detrimental effect on the lubrication of the journal and the bearings. ...

  18. A generalized non-local optical response theory for plasmonic nanostructures

    DEFF Research Database (Denmark)

    Mortensen, N. Asger; Raza, Søren; Wubs, Martijn

    2014-01-01

    for their description. Here instead we present a comparatively simple semiclassical generalized non-local optical response theory that unifies quantum pressure convection effects and induced charge diffusion kinetics, with a concomitant complex-valued generalized non-local optical response parameter. Our theory...

  19. Effects of Alloyed Carbon on the General Corrosion and the Pitting Corrosion Behavior of FeCrMnN Stainless Steels

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Heon-Young; Lee, Tae-Ho; Kim, Sung-Joon [Korea Institute of Materials Science, Changwon (Korea, Republic of)

    2011-10-15

    The effects of alloyed carbon on the pitting corrosion, the general corrosion, and the passivity behavior of Fe{sub 1}8Cr{sub 1}0Mn{sub 0}.4Nx{sub C} (x=0 ⁓ 0.38 wt%) alloys were investigated by various electrochemical methods and XPS analysis. The alloyed carbon increased the general corrosion resistance of the FeCrMnN matrix. Carbon enhanced the corrosion potential, reduced the metal dissolution rate, and accelerated the hydrogen evolution reaction rate in various acidic solutions. In addition, carbon promoted the pitting corrosion resistance of the matrix in a chloride solution. The alloyed carbon in the matrix increased the chromium content in the passive film, and thus the passive film became more protective.

  20. 42 CFR 93.100 - General policy.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false General policy. 93.100 Section 93.100 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON RESEARCH...

  1. Sebaran Generalized Extreme Value (GEV dan Generalized Pareto (GP untuk Pendugaan Curah Hujan Ekstrim di Wilayah DKI Jakarta

    Directory of Open Access Journals (Sweden)

    Achi Rinaldi

    2016-06-01

    Full Text Available Extreme event such as extreme rainfall have been analyzed and most concern for the country all around the world. There are two common distribution for extreme value which are Generalized Extreme Value distribution and Generalized Pareto distribution. These two distribution have shown good performace to estimate the parameter of  extreme value. This research was aim to estimate parameter of extreme value using GEV distribution and GP distribution, and also to characterized effect of extreme event such as flood. The rainfall data was taken from BMKG for 5 location in DKI Jakarta. Both of distribution shown a good perfromance. The resut showed that Tanjung Priok station has biggest location parameter for GEV and also the biggest scale parameter for GP, that mean the biggest probability to take flood effect of the extreme rainfall.

  2. The effectiveness of manual therapy, physiotherapy, and treatment by the general practitioner for nonspecific back and neck complaints : A randomized clinical trial

    NARCIS (Netherlands)

    Koes, B. W.; Bouter, L. M.; Van Mameren, H.; Essers, A. H.; Verstegen, G. M.; Hofhuizen, D. M.; Houben, J. P.; Knipschild, P. G.

    1992-01-01

    In a randomized trial, the effectiveness of manual therapy, physiotherapy, continued treatment by the general practitioner, and placebo therapy (detuned ultrasound and detuned short-wave diathermy) were compared for patients (n = 256) with nonspecific back and neck complaints lasting for at least 6

  3. Cost-effectiveness of i-Sleep, a guided online CBT intervention, for patients with insomnia in general practice: protocol of a pragmatic randomized controlled trial.

    Science.gov (United States)

    van der Zweerde, Tanja; Lancee, Jaap; Slottje, Pauline; Bosmans, Judith; Van Someren, Eus; Reynolds, Charles; Cuijpers, Pim; van Straten, Annemieke

    2016-04-02

    Insomnia is a highly prevalent disorder causing clinically significant distress and impairment. Furthermore, insomnia is associated with high societal and individual costs. Although cognitive behavioural treatment for insomnia (CBT-I) is the preferred treatment, it is not used often. Offering CBT-I in an online format may increase access. Many studies have shown that online CBT for insomnia is effective. However, these studies have all been performed in general population samples recruited through media. This protocol article presents the design of a study aimed at establishing feasibility, effectiveness and cost-effectiveness of a guided online intervention (i-Sleep) for patients suffering from insomnia that seek help from their general practitioner as compared to care-as-usual. In a pragmatic randomized controlled trial, adult patients with insomnia disorder recruited through general practices are randomized to a 5-session guided online treatment, which is called "i-Sleep", or to care-as-usual. Patients in the care-as-usual condition will be offered i-Sleep 6 months after inclusion. An ancillary clinician, known as the psychological well-being practitioner who works in the GP practice (PWP; in Dutch: POH-GGZ), will offer online support after every session. Our aim is to recruit one hundred and sixty patients. Questionnaires, a sleep diary and wrist actigraphy will be administered at baseline, post intervention (at 8 weeks), and at 6 months and 12 months follow-up. Effectiveness will be established using insomnia severity as the main outcome. Cost-effectiveness and cost-utility (using costs per quality adjusted life year (QALY) as outcome) will be conducted from a societal perspective. Secondary measures are: sleep diary, daytime consequences, fatigue, work and social adjustment, anxiety, alcohol use, depression and quality of life. The results of this trial will help establish whether online CBT-I is (cost-) effective and feasible in general practice as compared

  4. Aerosol indirect effects ? general circulation model intercomparison and evaluation with satellite data

    Energy Technology Data Exchange (ETDEWEB)

    Quaas, Johannes; Ming, Yi; Menon, Surabi; Takemura, Toshihiko; Wang, Minghuai; Penner, Joyce E.; Gettelman, Andrew; Lohmann, Ulrike; Bellouin, Nicolas; Boucher, Olivier; Sayer, Andrew M.; Thomas, Gareth E.; McComiskey, Allison; Feingold, Graham; Hoose, Corinna; Kristansson, Jon Egill; Liu, Xiaohong; Balkanski, Yves; Donner, Leo J.; Ginoux, Paul A.; Stier, Philip; Grandey, Benjamin; Feichter, Johann; Sednev, Igor; Bauer, Susanne E.; Koch, Dorothy; Grainger, Roy G.; Kirkevag, Alf; Iversen, Trond; Seland, Oyvind; Easter, Richard; Ghan, Steven J.; Rasch, Philip J.; Morrison, Hugh; Lamarque, Jean-Francois; Iacono, Michael J.; Kinne, Stefan; Schulz, Michael

    2010-03-12

    Aerosol indirect effects continue to constitute one of the most important uncertainties for anthropogenic climate perturbations. Within the international AEROCOM initiative, the representation of aerosol-cloud-radiation interactions in ten different general circulation models (GCMs) is evaluated using three satellite datasets. The focus is on stratiform liquid water clouds since most GCMs do not include ice nucleation effects, and none of the model explicitly parameterises aerosol effects on convective clouds. We compute statistical relationships between aerosol optical depth ({tau}{sub a}) and various cloud and radiation quantities in a manner that is consistent between the models and the satellite data. It is found that the model-simulated influence of aerosols on cloud droplet number concentration (N{sub d}) compares relatively well to the satellite data at least over the ocean. The relationship between {tau}{sub a} and liquid water path is simulated much too strongly by the models. This suggests that the implementation of the second aerosol indirect effect mainly in terms of an autoconversion parameterisation has to be revisited in the GCMs. A positive relationship between total cloud fraction (f{sub cld}) and {tau}{sub a} as found in the satellite data is simulated by the majority of the models, albeit less strongly than that in the satellite data in most of them. In a discussion of the hypotheses proposed in the literature to explain the satellite-derived strong f{sub cld} - {tau}{sub a} relationship, our results indicate that none can be identified as a unique explanation. Relationships similar to the ones found in satellite data between {tau}{sub a} and cloud top temperature or outgoing long-wave radiation (OLR) are simulated by only a few GCMs. The GCMs that simulate a negative OLR - {tau}{sub a} relationship show a strong positive correlation between {tau}{sub a} and f{sub cld} The short-wave total aerosol radiative forcing as simulated by the GCMs is

  5. General strategy for fabricating thoroughly mesoporous nanofibers

    KAUST Repository

    Hou, Huilin; Wang, Lin; Gao, Fengmei; Wei, Guodong; Tang, Bin; Yang, Weiyou; Wu, Tao

    2014-01-01

    mesoporous nanofibers with high purity and uniformity. Here, we report a general, simple and cost-effective strategy, namely, foaming-assisted electrospinning, for producing mesoporous nanofibers with high purity and enhanced specific surface areas. As a

  6. A general relativistic signature in the galaxy bispectrum: the local effects of observing on the lightcone

    Energy Technology Data Exchange (ETDEWEB)

    Umeh, Obinna; Jolicoeur, Sheean; Maartens, Roy [Department of Physics and Astronomy, University of the Western Cape, Robert Sobukwe Road, Cape Town 7535 (South Africa); Clarkson, Chris, E-mail: umeobinna@gmail.com, E-mail: beautifulheart369@gmail.com, E-mail: roy.maartens@gmail.com, E-mail: chris.clarkson@gmail.com [School of Physics and Astronomy, Queen Mary University of London, Mile End Road, London E1 4NS (United Kingdom)

    2017-03-01

    Next-generation galaxy surveys will increasingly rely on the galaxy bispectrum to improve cosmological constraints, especially on primordial non-Gaussianity. A key theoretical requirement that remains to be developed is the analysis of general relativistic effects on the bispectrum, which arise from observing galaxies on the past lightcone, as well as from relativistic corrections to the dynamics. As an initial step towards a fully relativistic analysis of the galaxy bispectrum, we compute for the first time the local relativistic lightcone effects on the bispectrum, which come from Doppler and gravitational potential contributions. For the galaxy bispectrum, the problem is much more complex than for the power spectrum, since we need the lightcone corrections at second order. Mode-coupling contributions at second order mean that relativistic corrections can be non-negligible at smaller scales than in the case of the power spectrum. In a primordial Gaussian universe, we show that the local lightcone projection effects for squeezed shapes at z ∼ 1 mean that the bispectrum can differ from the Newtonian prediction by ∼> 10% when the short modes are k ∼< (50 Mpc){sup −1}. These relativistic projection effects, if ignored in the analysis of observations, could be mistaken for primordial non-Gaussianity. For upcoming surveys which probe equality scales and beyond, all relativistic lightcone effects and relativistic dynamical corrections should be included for an accurate measurement of primordial non-Gaussianity.

  7. Management of upper dyspepsia in general practice

    DEFF Research Database (Denmark)

    Kjeldsen, Hans Christian; Kier, Svend; Husum, Gitte

    ) for two weeks. If symptoms were unchanged after to weeks => referral to endoscopy. Later recurrence of symptoms => endoscopy (> 45 year) or management strategy according to helicobacter pylori status and/or clinical reflux (measures...... of dyspepsia, dyspeptic episodes, main symptom, previous contact to general practice, previous gastroscopia, use of antacids or NSAID's, Helicobacter Pylori status and mental/physical well being (SF-36 measurement scale) (Table 1). After two weeks the GPs assessed 46 % of the patients to be free of symptoms...... Aim: To compare the effect of two strategies for management of dyspepsia. Evaluation based on GP's assessment after two weeks and patients assessment after three months.   Design: Prospective randomised controlled trial in general practice   Methods: 357 patients with dyspepsia where the general...

  8. Effects of different types of anaesthesia (regional vs general) on serum IL-6, IL-8 and M-CSF levels in surgical patients

    International Nuclear Information System (INIS)

    Xiao Jiawang

    2009-01-01

    Objective: To study the effect of anesthesia(regional vs general) on serum IL-6, IL-8 and M-CSF levels in surgical patients. Methods: Serum IL-6, IL-8 and M-CSF levels were determined with RIA 3 times in 34 patients operated under ragional anesthesia and 34 patients operted under general anesthesia (both for benign gastral ulcer). The levels were measured before induction of anesthesia, at beginning of operation and 1 hr later. Results: In patients under regional anesthesia, the IL-6, IL-8 and M-CSF levels increased significantly at the beginning of operation and 1 hr later. Though dropped remained significantly higher than the levels before induction (P<0.05); No significant change of the levels were obsorved in patients under general anesthesia through the operation, and the levels were as a whole significantly lower than the levels under regional anesthesia (P<0.05). Conclusion: General anesthesia (combined intravenous and inhalation) could abolish increases of serum IL-6, IL-8 and M-CSF levels during operation must be of clinical values. (authors)

  9. Action principle for the generalized harmonic formulation of general relativity

    International Nuclear Information System (INIS)

    Brown, J. David

    2011-01-01

    An action principle for the generalized harmonic formulation of general relativity is presented. The action is a functional of the spacetime metric and the gauge source vector. An action principle for the Z4 formulation of general relativity has been proposed recently by Bona, Bona-Casas, and Palenzuela. The relationship between the generalized harmonic action and the Bona, Bona-Casas, and Palenzuela action is discussed in detail.

  10. Generalized Synchronization of Time-Delayed Discrete Systems

    International Nuclear Information System (INIS)

    Jing Jianyi; Min Lequan

    2009-01-01

    This paper establishes two theorems for two time-delayed (chaotic) discrete systems to achieve time-delayed generalized synchronization (TDGS). These two theorems uncover the general forms of two TDGS systems via a prescribed transformation. As examples, we convert the Lorenz three-dimensional chaotic map to an equal time-delayed system as the driving system, and construct the TDGS driven systems according to the Theorems 1 and 2. Numerical simulations demonstrate the effectiveness of the proposed theorems. (interdisciplinary physics and related areas of science and technology)

  11. Moral Reasoning in College Students: Effects of Two General Education Curricula.

    Science.gov (United States)

    Mustapha, Sherry L.; Seybert, Jeffrey A.

    1991-01-01

    Two different approaches to the undergraduate general education and liberal arts curricula were studied in terms of moral reasoning for 188 college students. Results reveal more advanced levels of moral reasoning for students in the integrated curriculum organized around decision making than for those in the traditional curriculum. (SLD)

  12. Effects of positive end-expiratory pressure on arthroscopic shoulder surgery under general anesthesia.

    Science.gov (United States)

    Ersoy, Ayşın; Çakırgöz, Mensure; Ervatan, Zekeriya; Kıran, Özlem; Türkmen, Aygen; Esenyel, Cem Zeki

    2016-01-01

    Our study is a prospective, randomized study on patients undergoing arthroscopic shoulder surgery in the beach-chair position to evaluate the effects of positive end-expiratory pressure (PEEP) on hemodynamic stability, providing a bloodless surgical field and surgical satisfaction. Fifty patients were divided into two groups. Group I (n=25) had zero end-expiratory pressure (ZEEP) administered under general anesthesia, and group II (n=25) had +5 PEEP administered. During surgery, intraarticular hemorrhage and surgical satisfaction were evaluated on a scale of 0-10. During surgery, at the 5th, 30th, 60th, and 90th minutes and at the end of surgery, heart rate, mean arterial pressure (MAP), and positive inspiratory pressure were recorded. At the end of the surgery, the amount of bleeding and duration of the operation were recorded. In group I, the duration of operation and amount of bleeding were found to be significantly greater than those in group II (pshoulder surgery in the beach-chair position reduces the amount of hemorrhage in the surgical field and thus increases surgical satisfaction without requiring the creation of controlled hypotension.

  13. Effect of Low-Dose (Single-Dose Magnesium Sulfate on Postoperative Analgesia in Hysterectomy Patients Receiving Balanced General Anesthesia

    Directory of Open Access Journals (Sweden)

    Arman Taheri

    2015-01-01

    Full Text Available Background and Aim. Aparallel, randomized, double blinded, placebo-controlled trial study was designed to assess the efficacy of single low dose of intravenous magnesium sulfate on post-total abdominal hysterectomy (TAH pain relief under balanced general anesthesia. Subject and Methods. Forty women undergoing TAH surgery were assigned to two magnesium sulfate (N=20 and normal saline (N=20 groups randomly. The magnesium group received magnesium sulfate 50 mg·kg−1 in 100 mL of normal saline solution i.v as single-dose, just 15 minutes before induction of anesthesia whereas patients in control group received 100 mL of 0.9% sodium chloride solution at the same time. The same balanced general anesthesia was induced for two groups. Pethidine consumption was recorded over 24 hours precisely as postoperative analgesic. Pain score was evaluated with Numeric Rating Scale (NRS at 0, 6, 12, and 24 hours after the surgeries. Results. Postoperative pain score was lower in magnesium group at 6, 12, and 24 hours after the operations significantly (P<0.05. Pethidine requirement was significantly lower in magnesium group throughout 24 hours after the surgeries (P=0.0001. Conclusion. Single dose of magnesium sulfate during balanced general anesthesia could be considered as effective and safe method to reduce postoperative pain and opioid consumption after TAH.

  14. Generalized Lorenz-Mie Theories

    CERN Document Server

    Gouesbet, Gérard

    2011-01-01

    The Lorenz-Mie theory, describing the interaction between a homogeneous sphere and an electromagnetic plane wave, is likely to be one of the most famous theories in light scattering. But, with the advent of lasers and their increasing development in various fields, it has become too old-fashioned to meet most of the modern requisites. The book deals with generalized Lorenz-Mie theories when the illuminating beam is an electromagnetic arbitrary shaped beam, relying on the method of separation of variables. A particular emphasis is stressed on the case of the homogeneous sphere but other regular particles are considered too. An extensive discussion of the methods available to the evaluation of beam shape coefficients describing the illuminating beam is provided, and several methods are discussed. Applications concern many fields such as optical particle sizing and, more generally, optical particle characterization, morphology-dependent resonances, or mechanical effects of light for optical trapping, optical twe...

  15. Categorization = Decision Making + Generalization

    Science.gov (United States)

    Seger, Carol A; Peterson, Erik J.

    2013-01-01

    We rarely, if ever, repeatedly encounter exactly the same situation. This makes generalization crucial for real world decision making. We argue that categorization, the study of generalizable representations, is a type of decision making, and that categorization learning research would benefit from approaches developed to study the neuroscience of decision making. Similarly, methods developed to examine generalization and learning within the field of categorization may enhance decision making research. We first discuss perceptual information processing and integration, with an emphasis on accumulator models. We then examine learning the value of different decision making choices via experience, emphasizing reinforcement learning modeling approaches. Next we discuss how value is combined with other factors in decision making, emphasizing the effects of uncertainty. Finally, we describe how a final decision is selected via thresholding processes implemented by the basal ganglia and related regions. We also consider how memory related functions in the hippocampus may be integrated with decision making mechanisms and contribute to categorization. PMID:23548891

  16. Interventions addressing general parenting to prevent or treat childhood obesity.

    Science.gov (United States)

    Gerards, Sanne M P L; Sleddens, Ester F C; Dagnelie, Pieter C; de Vries, Nanne K; Kremers, Stef P J

    2011-06-01

    Observational studies increasingly emphasize the impact of general parenting on the development of childhood overweight and obesity. The aim of the current literature review was to provide an overview of interventions addressing general parenting in order to prevent or treat childhood obesity. Electronic literature databases were systematically searched for relevant studies. Seven studies were eligible for inclusion. The studies described four different general parenting programs, which were supplemented with lifestyle components (i.e., physical activity and nutrition). All studies showed significant small to moderate intervention effects on at least one weight-related outcome measure. The current review shows that despite the emerging observational evidence for the role of parenting in children's weight-related outcomes, few interventions have been developed that address general parenting in the prevention of childhood obesity. These interventions provide evidence that the promotion of authoritative parenting is an effective strategy for the prevention and management of childhood obesity.

  17. The Effects of Coping Therapy on General Health of Pregnant Women with High Risk of Genetics Abnormalities in their Fetus

    Directory of Open Access Journals (Sweden)

    F Nazmiye

    2016-11-01

    Full Text Available Introduction: The physiological changes in pregnancy lead to the psychological pressures. Therefore, there is a need for applying cognitive behavioral and emotional confronting to encounter these problems. The present research investigated the effect of coping therapy on general health of pregnant women with high risk of genetic abnormalities in their fetus. Methods: The present study was a semi experimental research. Pre and post tests were used to investigate coping therapy between 30 pregnant women who were referred to Khatomolanbia Genetic Clinic, Yazd, Iran. All the women had pregnancy screening test with high risk of genetics abnormalities in their fetus. They were divided randomly into two groups of case and controls. The test of GHQ was performed in both groups, then the case groups went under 8 sessions of teaching coping therapy each lasting 120 min. After finishing the sessions, post test was performed and analyzing the data using descriptive statistical index and covariance analysis test. Results: Teaching coping therapy to case group caused improvement in their GHQ mark, and this change was significantly different from the change in the GHQ mark of control group. In addition, there was a significant decrease in anxiety, depression and physical signs and an improvement of social function in case group compare to the control group. Discussion: Teaching coping therapy can improve the general health of pregnant women with high risk of genetic abnormalities in their fetus. Therefore, presenting educational courses to the women can improve their general health indices in addition to preventing the probable effects of stress on fetus.

  18. Generalized polygons

    CERN Document Server

    Van Maldeghem, Hendrik

    1998-01-01

    Generalized Polygons is the first book to cover, in a coherent manner, the theory of polygons from scratch. In particular, it fills elementary gaps in the literature and gives an up-to-date account of current research in this area, including most proofs, which are often unified and streamlined in comparison to the versions generally known. Generalized Polygons will be welcomed both by the student seeking an introduction to the subject as well as the researcher who will value the work as a reference. In particular, it will be of great value for specialists working in the field of generalized polygons (which are, incidentally, the rank 2 Tits-buildings) or in fields directly related to Tits-buildings, incidence geometry and finite geometry. The approach taken in the book is of geometric nature, but algebraic results are included and proven (in a geometric way!). A noteworthy feature is that the book unifies and generalizes notions, definitions and results that exist for quadrangles, hexagons, octagons - in the ...

  19. Predicting the multi-domain progression of Parkinson's disease: a Bayesian multivariate generalized linear mixed-effect model.

    Science.gov (United States)

    Wang, Ming; Li, Zheng; Lee, Eun Young; Lewis, Mechelle M; Zhang, Lijun; Sterling, Nicholas W; Wagner, Daymond; Eslinger, Paul; Du, Guangwei; Huang, Xuemei

    2017-09-25

    It is challenging for current statistical models to predict clinical progression of Parkinson's disease (PD) because of the involvement of multi-domains and longitudinal data. Past univariate longitudinal or multivariate analyses from cross-sectional trials have limited power to predict individual outcomes or a single moment. The multivariate generalized linear mixed-effect model (GLMM) under the Bayesian framework was proposed to study multi-domain longitudinal outcomes obtained at baseline, 18-, and 36-month. The outcomes included motor, non-motor, and postural instability scores from the MDS-UPDRS, and demographic and standardized clinical data were utilized as covariates. The dynamic prediction was performed for both internal and external subjects using the samples from the posterior distributions of the parameter estimates and random effects, and also the predictive accuracy was evaluated based on the root of mean square error (RMSE), absolute bias (AB) and the area under the receiver operating characteristic (ROC) curve. First, our prediction model identified clinical data that were differentially associated with motor, non-motor, and postural stability scores. Second, the predictive accuracy of our model for the training data was assessed, and improved prediction was gained in particularly for non-motor (RMSE and AB: 2.89 and 2.20) compared to univariate analysis (RMSE and AB: 3.04 and 2.35). Third, the individual-level predictions of longitudinal trajectories for the testing data were performed, with ~80% observed values falling within the 95% credible intervals. Multivariate general mixed models hold promise to predict clinical progression of individual outcomes in PD. The data was obtained from Dr. Xuemei Huang's NIH grant R01 NS060722 , part of NINDS PD Biomarker Program (PDBP). All data was entered within 24 h of collection to the Data Management Repository (DMR), which is publically available ( https://pdbp.ninds.nih.gov/data-management ).

  20. Effect of Systematic Follow-Up by General Practitioners after Deliberate Self-Poisoning: A Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Tine K Grimholt

    Full Text Available To assess whether systematic follow-up by general practitioners (GPs of cases of deliberate self-poisoning (DSP by their patients decreases psychiatric symptoms and suicidal behaviour compared with current practice.Randomised clinical trial with two parallel groups.General practices in Oslo and the eastern part of Akershus County.Patients aged 18-75 years admitted to hospital for DSP. We excluded patients diagnosed with psychoses, without a known GP, those not able to complete a questionnaire, and patients admitted to psychiatric in-patient care or other institutions where their GP could not follow them immediately after discharge.The GPs received a written guideline, contacted the patients and scheduled a consultation within one week after discharge, and then provided regular consultations for six months. We randomised the patients to either intervention (n = 78 or treatment as usual (n = 98.Primary outcome measure was the Beck Scale for Suicide Ideation (SSI. Secondary outcomes were Beck Depression Inventory (BDI and Beck Hopelessness Scale (BHS, self-reported further self-harm and treatment for DSP in a general hospital or an emergency medical agency (EMA. We assessed patients on entry to the trial and at three and six months. We collected data from interviews, self-report questionnaires, and hospital and EMA medical records.There were no significant differences between the groups in SSI, BDI, or BHS mean scores or change from baseline to three or six months. During follow-up, self-reported DSP was 39.5% in the intervention group vs. 15.8% in controls (P = 0.009. Readmissions to general hospitals were similar (13% in both groups (P = 0.963, while DSP episodes treated at EMAs were 17% in the intervention group and 7% in the control group (P = 0.103.Structured follow-up by GPs after an episode of DSP had no significant effect on suicide ideation, depression or hopelessness. There was no significant difference in repeated episodes of DSP in

  1. Impuestos al capital y al trabajo en Colombia: un análisis mediante equilibrio general computable Effect of Taxes on Capital and Labor in Colombia: A Computable General Equilibrium Analysis

    Directory of Open Access Journals (Sweden)

    Jesús Botero Garcia

    2011-10-01

    Full Text Available Mediante un modelo de equilibrio general computable, calibrado para Colombia, se analiza el impacto de diversas políticas económicas, que afectan el precio relativo de los factores productivos. Se concluye que los estímulos a la inversión, que pueden interpretarse como acciones que disminuyen el precio del capital, propician sin embargo la acumulación de capital, y por esa vía, incrementan la productividad del trabajo, generando efectos positivos netos sobre el empleo. La eliminación de los aportes parafiscales, por su parte, genera una reducción en el costo del trabajo, pero su efecto global sobre el empleo es compensado parcialmente por las acciones fiscales tendientes a generar rentas alternativas que permitan mantener los beneficios asociados a esos aportes. Se sugiere que el esquema ideal sería aquel que establece estímulos a la inversión, focalizados hacia sectores intensivos en empleo, al tiempo que crea redes de protección social adecuadas, para enfrentar los problemas asociados a la pobreza.   Abstract Using a computable general equilibrium model, calibrated for Colombia, it is analyze the impact of various economic policies, which affect the relative price of production factors. The results concluded that the incentives for investment, which can be interpreted as actions that decrease the cost of capital, however lead to the accumulation of capital, and thereby increase the productivity of labour, generating net positive effects on employment. The Elimination of the payroll taxes, for its part, generates a reduction in the cost of labour, but their overall effect on employment is partially offset by the tax measures designed to generate alternative income to keep the benefits associated with these contributions. Finally the suggestion is that the ideal scheme would be one that provides incentives for investment, focused towards employment-intensive sectors, at the time that creates networks of social protection appropriate

  2. Effect of screening and lifestyle counselling on incidence of ischaemic heart disease in general population

    DEFF Research Database (Denmark)

    Jørgensen, Torben; Jacobsen, Rikke Kart; Toft, Ulla

    2014-01-01

    of Copenhagen, Denmark. PARTICIPANTS: 59,616 people aged 30-60 years randomised with different age and sex randomisation ratios to an intervention group (n = 11,629) and a control group (n = 47,987). INTERVENTION: The intervention group was invited for screening, risk assessment, and lifestyle counselling up...... sessions of group based lifestyle counselling on smoking cessation, diet, and physical activity. After five years all were invited for a final counselling session. Participants were referred to their general practitioner for medical treatment, if relevant. The control group was not invited for screening......OBJECTIVE: To investigate the effect of systematic screening for risk factors for ischaemic heart disease followed by repeated lifestyle counselling on the 10 year development of ischaemic heart disease at a population level. DESIGN: Randomised controlled community based trial. SETTING: Suburbs...

  3. Generalized irreversible heat-engine experiencing a complex heat-transfer law

    International Nuclear Information System (INIS)

    Chen Lingen; Li Jun; Sun Fengrui

    2008-01-01

    The fundamental optimal relation between optimal power-output and efficiency of a generalized irreversible Carnot heat-engine is derived based on a generalized heat-transfer law, including a generalized convective heat-transfer law and a generalized radiative heat-transfer law, q ∝ (ΔT n ) m . The generalized irreversible Carnot-engine model incorporates several internal and external irreversibilities, such as heat resistance, bypass heat-leak, friction, turbulence and other undesirable irreversibility factors. The added irreversibilities, besides heat resistance, are characterized by a constant parameter and a constant coefficient. The effects of heat-transfer laws and various loss terms are analyzed. The results obtained corroborate those in the literature

  4. Overview of 71 European community-based initiatives against childhood obesity starting between 2005 and 2011: general characteristics and reported effects.

    Science.gov (United States)

    Bemelmans, Wanda Jose Erika; Wijnhoven, Trudy Maria Arnoldina; Verschuuren, Marieke; Breda, João

    2014-07-28

    Community-based initiatives (CBIs) on childhood obesity are considered a good practice approach against childhood obesity. The European Commission called for an overview of CBIs implemented from 2005-2011. A survey was executed by the National Institute for Public Health and the Environment of the Netherlands, in collaboration with the World Health Organization Regional Office for Europe. The objective of this paper is to provide an overview of the European CBIs, as identified in the survey, presenting their general characteristics, applied strategies (separately for actions targeting the environment and/or directly the children's behaviour) and the reported effects on weight indicators. Potentially eligible CBIs were identified by informants in 27 European Union countries, Iceland, Liechtenstein, Norway, and Switzerland, and through desk research. School based approaches could be included if they complied with criteria related to being 'community-based'. In total, 278 potential eligible CBIs were identified and of these, 260 projects were approached. For 88 an electronic questionnaire was completed; of these 71 met all criteria. The included projects were reported by 15 countries. 66% of the 71 CBIs implemented actions in more than one setting or throughout the neighbourhood. Most frequently reported environmental actions were professional training (78%), actions for parents (70%), and changing the social (62%) and physical (52%) environment. Most frequently reported educational activities were group education (92%), general educational information (90%), and counselling sessions (58%). The vast majority (96%) implemented both environmental and individual strategies and about half of the CBIs reported a public-private partnership. Eight CBIs provided evidence supporting positive effects on weight indicators and/or overweight prevalence in a general population of children (aged 6 to 12 yrs), and one CBI did not support this. Two of those CBIs were also conducted

  5. The generalized effective potential and its equations of motion

    International Nuclear Information System (INIS)

    Ananikyan, N.S.; Savvidy, G.K.

    1980-01-01

    By means ot the Legendre transformations a functional GITA(PHI, G, S) is constructed which depends on PHI -a possible expectation value of the quantum field, G -a possible expectation value of the 2-point connected Green function and S= - a possible expectation value of the classical action. The motion equations for the functional GITA are derived on the example of the gPHI 3 theory and an iteration technique is suggested to solve them. A basic equation for GITA which is solved by means of iteration techniques is an ordinary and not a variation one, as it is the case at usual Legendre transformations. The developed formalism can be easily generalized as to other theories

  6. Further analysis of scintillation index for a laser beam propagating through moderate-to-strong non-Kolmogorov turbulence based on generalized effective atmospheric spectral model

    Science.gov (United States)

    Ma, Jing; Fu, Yu-Long; Yu, Si-Yuan; Xie, Xiao-Long; Tan, Li-Ying

    2018-03-01

    A new expression of the scintillation index (SI) for a Gaussian-beam wave propagating through moderate-to-strong non-Kolmogorov turbulence is derived, using a generalized effective atmospheric spectrum and the extended Rytov approximation theory. Finite inner and outer scale parameters and high wave number “bump” are considered in the spectrum with a generalized spectral power law in the range of 3–4, instead of the fixed classical Kolmogorov power law of 11/3. The obtained SI expression is then used to analyze the effects of the spectral power law and the inner scale and outer scale on SI under various non-Kolmogorov fluctuation conditions. These results will be useful in future investigations of optical wave propagation through atmospheric turbulence.

  7. Stochastic abstract policies: generalizing knowledge to improve reinforcement learning.

    Science.gov (United States)

    Koga, Marcelo L; Freire, Valdinei; Costa, Anna H R

    2015-01-01

    Reinforcement learning (RL) enables an agent to learn behavior by acquiring experience through trial-and-error interactions with a dynamic environment. However, knowledge is usually built from scratch and learning to behave may take a long time. Here, we improve the learning performance by leveraging prior knowledge; that is, the learner shows proper behavior from the beginning of a target task, using the knowledge from a set of known, previously solved, source tasks. In this paper, we argue that building stochastic abstract policies that generalize over past experiences is an effective way to provide such improvement and this generalization outperforms the current practice of using a library of policies. We achieve that contributing with a new algorithm, AbsProb-PI-multiple and a framework for transferring knowledge represented as a stochastic abstract policy in new RL tasks. Stochastic abstract policies offer an effective way to encode knowledge because the abstraction they provide not only generalizes solutions but also facilitates extracting the similarities among tasks. We perform experiments in a robotic navigation environment and analyze the agent's behavior throughout the learning process and also assess the transfer ratio for different amounts of source tasks. We compare our method with the transfer of a library of policies, and experiments show that the use of a generalized policy produces better results by more effectively guiding the agent when learning a target task.

  8. What's the effect of the implementation of general practitioner cooperatives on caseload? Prospective intervention study on primary and secondary care.

    Science.gov (United States)

    Philips, Hilde; Remmen, Roy; Van Royen, Paul; Teblick, Marc; Geudens, Leo; Bronckaers, Marc; Meeuwis, Herman

    2010-07-30

    Out-of-hours care in the primary care setting is rapidly changing and evolving towards general practitioner 'cooperatives' (GPC). GPCs already exist in the Netherlands, the United Kingdom and Scandinavia, all countries with strong general practice, including gatekeepers' role. This intervention study reports the use and caseload of out-of-hours care before and after implementation of a GPC in a well subscribed region in a country with an open access health care system and no gatekeepers' role for general practice. We used a prospective before/after interventional study design. The intervention was the implementation of a GPC. One year after the implementation of a GPC, the number of patient contacts in the intervention region significantly increased at the GPC (OR: 1.645; 95% CI: 1.439-1.880), while there were no significant changes in patient contacts at the Emergency Department (ED) or in other regions where a simultaneous registration was performed. Although home visits decreased in all general practitioner registrations, the difference was more pronounced in the intervention region (intervention region: OR: 0.515; 95% CI: 0.411-0.646, other regions: OR: 0.743; 95% CI: 0.608-0.908). At the ED we observed a decrease in the number of trauma cases (OR: 0.789; 95% CI: 0.648-0.960) and of patients who came to hospital by ambulance (OR: 0.687; 95% CI: 0.565-0.836). One year after its implementation more people seek help at the GPC, while the number of contacts at the ED remains the same. The most prominent changes in caseload are found in the trauma cases. Establishing a GPC in an open health care system, might redirect some patients with particular medical problems to primary care. This could lead to a lowering of costs or a more cost-effective out of hours care, but further research should focus on effective usage to divert patient flows and on quality and outcome of care.

  9. Effects of General and Epidural Anaesthesia in Newborn’s Stres Hormones, Blood Gases, and Apgar Scores in Elective Cesarean Section

    Directory of Open Access Journals (Sweden)

    Meral Ezberci

    2005-12-01

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the effects of general and epidural anaesthesia in newborn’s stres hormones, blood gases, and Apgar scores in elective cesarean section. MATERIALS-METHODS: 50 patients in ASA II (American Society of Anesthesiology class who would undergo elective cesarean section in University of Kahramanmaras Sutcuimam, Department of Anaesthesiology and Reanimation included in the study and randomized into two equal groups (General anaesthesia: Group G and Epidural anaesthesia: Group E. In both groups, newborn stres hormones (TSH, cortisol, and insulin, blood gases, and Apgar scores were studued. All patients received famotidine and granisetron iv 30 min before operations in premedication room. In the general anaesthesia group; aritmal, propofol, and succinylcholine was used for induction and muscle relaxation. Following the induction, positive pressure ventilation of the lungs was started immediately using a 50% N2O + O2 mixture. After delivery of the baby, anaesthesia and muscle relaxation was maintained by 50% N2O +O2, 0,5-1% MAC isoflurane, and cisatracurium. In the epidural anaesthesia group; epidural anaesthesia was performed with 0,375% bupivacaine. The epidural needle inserted through L2-3 or L3-4 interspace. After achieving T4-5 neural blockade, the operation was started. Blood samples for newborn stres hormones and blood gases were taken from umblical vein. The Apgar scores were recorded at 1 min and again at 5 min after the delivery by same person. RESULTS: There were no differences in newborn stress hormones between two groups. In newborn blood gases analyses, only SO2 changes were statistically significant between two groups. There were no differences in newborn Apgar scores between two groups. CONCLUSION: With these results, we concluded that each of the general and epidural anaesthesia techniques have similar effects on newborn blood gases, stress hormones and Apgar scores and can be acceptable

  10. Structural Behavioral Study on the General Aviation Network Based on Complex Network

    Science.gov (United States)

    Zhang, Liang; Lu, Na

    2017-12-01

    The general aviation system is an open and dissipative system with complex structures and behavioral features. This paper has established the system model and network model for general aviation. We have analyzed integral attributes and individual attributes by applying the complex network theory and concluded that the general aviation network has influential enterprise factors and node relations. We have checked whether the network has small world effect, scale-free property and network centrality property which a complex network should have by applying degree distribution of functions and proved that the general aviation network system is a complex network. Therefore, we propose to achieve the evolution process of the general aviation industrial chain to collaborative innovation cluster of advanced-form industries by strengthening network multiplication effect, stimulating innovation performance and spanning the structural hole path.

  11. Effectiveness of a training course for general practice nurses in motivation support in type 2 diabetes care: a cluster-randomised trial.

    Science.gov (United States)

    Juul, Lise; Maindal, Helle T; Zoffmann, Vibeke; Frydenberg, Morten; Sandbaek, Annelli

    2014-01-01

    Type 2 diabetes is a common metabolic disease with the potential for prevention of complications. The prevention requires a high level of lasting actions from the patients, which may be burdensome. The aim of this trial was to evaluate the effectiveness of a training course for general practice nurses in motivation support at 18 months follow-up in the affiliated type 2 diabetes population. Forty general practices with nurse-led diabetes consultations from the area of Aarhus, Denmark were randomised 1∶1 to either intervention or usual practice. Intervention practices were offered a 16-hour Self-determination theory-based course including communication training for general practice nurses delivered over 10 months. The affiliated diabetes populations (aged 40-74 years) were identified from registers (intervention n = 2,005; usual n = 2,029). Primary outcomes were register-based glycated haemoglobin (HbA1c) -, total cholesterol levels, and well-being measured by the Problem Areas In Diabetes scale (PAID) and the mental component summary score, SF12 (SF12, mcs). Intention-to-treat analyses were performed. Predefined subgroups analyses were performed. The differences between the intervention- and the control practices' mean HbA1c and total cholesterol at follow-up adjusted for baseline values and clustering were respectively: -0.02%-points (95% CI: -0.11 to 0.07; p: 0.67); 0.08 mmol/l (95% CI: 0.01 to 0.15; p: 0.02). Differences in median scores adjusted for clustering were for PAID: 1.25; p = 0.31 and SF12, mcs: 0.99; p = 0.15. Women in intervention practices differed from women in usual practices on mean HbA1c: -0.12%-points (-0.23 to -0.02; p = 0.02) and SF12, mcs: 2.6; p = 0.01. Offering a training course for general practice nurses in applying the Self-determination theory in current type 2 diabetes care had no effect compared with usual practice measured by HbA1c and total cholesterol levels and the well-being at 18 months of follow-up in

  12. Third-order perturbations of a zero-pressure cosmological medium: Pure general relativistic nonlinear effects

    International Nuclear Information System (INIS)

    Hwang, Jai-chan; Noh, Hyerim

    2005-01-01

    We consider a general relativistic zero-pressure irrotational cosmological medium perturbed to the third order. We assume a flat Friedmann background but include the cosmological constant. We ignore the rotational perturbation which decays in expanding phase. In our previous studies we discovered that, to the second-order perturbation, except for the gravitational wave contributions, the relativistic equations coincide exactly with the previously known Newtonian ones. Since the Newtonian second-order equations are fully nonlinear, any nonvanishing third- and higher-order terms in the relativistic analyses are supposed to be pure relativistic corrections. In this work, we derive such correction terms appearing in the third order. Continuing our success in the second-order perturbations, we take the comoving gauge. We discover that the third-order correction terms are of φ v order higher than the second-order terms where φ v is a gauge-invariant combination related to the three-space curvature perturbation in the comoving gauge; compared with the Newtonian potential, we have δΦ∼(3/5)φ v to the linear order. Therefore, the pure general relativistic effects are of φ v order higher than the Newtonian ones. The corrections terms are independent of the horizon scale and depend only on the linear-order gravitational potential (curvature) perturbation strength. From the temperature anisotropy of cosmic microwave background, we have (δT/T)∼(1/3)δΦ∼(1/5)φ v ∼10 -5 . Therefore, our present result reinforces our previous important practical implication that near the current era one can use the large-scale Newtonian numerical simulation more reliably even as the simulation scale approaches near (and goes beyond) the horizon

  13. An evaluation of the effectiveness of psychological therapy in reducing general psychological distress for adults with autism spectrum conditions and comorbid mental health problems.

    Science.gov (United States)

    Blainey, Sarah H; Rumball, Freya; Mercer, Louise; Evans, Lauren Jayne; Beck, Alison

    2017-11-01

    To investigate the effectiveness of psychological therapy in reducing psychological distress for adults with autism spectrum conditions (ASC) and co-morbid mental health conditions in routine clinical practice. To explore the effect of individual characteristics and service factors on change in general distress. In a specialist psychological therapies service for adults with ASC, the Clinical Outcomes in Routine Evaluation-Outcome Measure (CORE-OM) self-report questionnaire of psychological distress is completed by clients at start and end of therapy. Change over time and reliable and clinical change was assessed for 81 of a total of 122 clients (66.4%). Factors which may influence change over time were explored using available clinical information. Overall, there was a significant reduction in CORE-OM score during therapy with a small effect size. Most clients showed an improvement in psychological distress over therapy (75.4% improved, with 36.9% of these showing reliable changes). Significant and comparable reductions from pre-therapy to post-therapy were seen across the sample, showing that individual differences did not mediate therapy effectiveness. CORE-OM scores mediate the association between age of ASD diagnosis and hours of therapeutic input required, with greater age at diagnosis and higher distress associated with longer therapy duration. Our preliminary findings suggest that psychological therapy may be effective in reducing general distress for clients with ASC and co-morbid mental health conditions and should be routinely offered. Individuals who are diagnosed with ASD in adulthood are likely to require a longer course of therapy when their general distress scores are high. Copyright © 2017 John Wiley & Sons, Ltd.

  14. Small business, cash budgets and general practice.

    Science.gov (United States)

    Jackson, A R

    1991-01-01

    In practice management, general practice falls into the category of small business with all its attendant generic problems. Disciplined planning and good financial management are not often seen in small business. These are required if general practitioners are to continue (or return to) the provision of high quality medical services. An effective budget process, especially cash-flow budgeting, is the key to successful planning and financial management. Budgeting will bring Control, Co-ordination, and Credibility to your practice. It will enable you to set goals and to achieve them.

  15. Is the Generally Held View That Intravenous Dihydroergotamine Is Effective in Migraine Based on Wrong "General Consensus" of One Trial? A Critical Review of the Trial and Subsequent Quotations.

    Science.gov (United States)

    Bekan, Goran; Tfelt-Hansen, Peer

    2016-10-01

    The claim that parenteral dihydroergotamine (DHE) is effective in migraine is based on one randomized, placebo-controlled, crossover trial from 1986. The aim of this review was to critically evaluate the original article. It was also found to be of interest to review quotes concerning the results in the more than 100 articles subsequently referring to the article. The correctness of the stated effect of intravenous DHE in the randomized clinical trial (RCT) was first critically evaluated. Then, Google Scholar was searched for references to the article and these references were classified as to whether they judged the reported RCT as positive or negative. The design of the RCT, with a crossover within one migraine attack, only allows evaluation of the results for the first period and the effect of DHE and placebo were quite comparable. About 151 references were found for the article in Google scholar. Among the 95 articles with a judgment on the efficacy of intravenous DHE in the RCT, 90 stated that DHE was effective or likely effective whereas only 5 articles stated that DHE was ineffective. Despite a "negative" RCT, authors of subsequent articles on the efficacy of parenteral DHE overwhelmingly reported this RCT as "positive." This is probably due to the fact that the authors concluded in the abstract that DHE is effective, and to a kind of "wrong general consensus." © 2016 American Headache Society.

  16. Can the dopaminergic-related effects of general anesthetics be linked to mechanisms involved in drug abuse and addiction?

    Science.gov (United States)

    Melo, A; Tavares, I; Sousa, N; Pêgo, J M

    2015-08-01

    General anesthetics (GA) are well known for the ability to induce a state of reversible loss of consciousness and unresponsiveness to painful stimuli. However, evidence from animal models and clinical studies show that GA exposure may induce behavioral changes beyond acute effects. Most research and concerns are focused on changes in cognition and memory. We will look at effects of GA on behavior that is mediated by the dopaminergic system. Pharmacological resemblance of GA with drugs of abuse, and the complexity and importance of dopaminergic systems in both reward seeking and addictive illnesses make us believe that it deserves an overview about what is already known and what matters to us as healthcare workers and specifically as anesthesiologists. A review of available evidence strongly suggests that there may be a link between the effects of GA on the brain and substance abuse, partly explained by their influence on the dopaminergic system. © 2015 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

  17. Second-order generalized perturbation theory for source-driven systems

    International Nuclear Information System (INIS)

    Greenspan, E.; Gilai, D.; Oblow, E.M.

    1978-01-01

    A second-order generalized perturbation theory (GPT) for the effect of multiple system variations on a general flux functional in source-driven systems is derived. The derivation is based on a functional Taylor series in which second-order derivatives are retained. The resulting formulation accounts for the nonlinear effect of a given variation accurate to third order in the flux and adjoint perturbations. It also accounts for the effect of interaction between any number of variations. The new formulation is compared with exact perturbation theory as well as with perturbation theory for altered systems. The usefulnes of the second-order GPT formulation is illustrated by applying it to optimization problems. Its applicability to areas of cross-section sensitivity analysis and system design and evaluation is also discussed

  18. The effect on outcome of peribulbar anaesthesia in conjunction with general anesthesia for vitreoretinal surgery.

    Science.gov (United States)

    Ghali, A M; El Btarny, A M

    2010-03-01

    The purpose of this study was to evaluate peri-operative outcome after vitreoretinal surgery when peribulbar anaesthesia is combined with general anaesthesia. Sixty adult patients undergoing elective primary retinal detachment surgery with scleral buckling or an encircling procedure received either peribulbar anaesthesia in conjunction with general anaesthesia or general anaesthesia alone. For peribulbar anaesthesia a single percutaneous injection of 5-7 ml of local anaesthetic solution (0.75% ropivacaine with hyaluronidase 15 iu.ml(-1)) was used. The incidence of intra-operative oculocardiac reflex and surgical bleeding interfering with the surgical field, postoperative pain and analgesia requirements, and postoperative nausea and vomiting were recorded. In the block group there was a lower incidence of oculocardiac reflex and surgical bleeding intra-operatively. Patients in the block group also had better postoperative analgesia and a lower incidence of postoperative nausea and vomiting compared with the group without a block. The use of peribulbar anaesthesia in conjunction with general anesthesia was superior to general anaesthesia alone for vitreoretinal surgery with scleral buckling.

  19. Engineering a General Education Program: Designing Mechanical Engineering General Education Courses

    Science.gov (United States)

    Fagette, Paul; Chen, Shih-Jiun; Baran, George R.; Samuel, Solomon P.; Kiani, Mohammad F.

    2013-01-01

    The Department of Mechanical Engineering at our institution created two engineering courses for the General Education Program that count towards second level general science credit (traditional science courses are first level). The courses were designed for the general student population based upon the requirements of our General Education Program…

  20. Effect of physical and psychological puberty training on general well being and its dimensions in girl students

    Directory of Open Access Journals (Sweden)

    Shahrban Mehrabi

    2018-03-01

    Full Text Available Transition through puberty is marked by an increased risk for the onset of a range of health problems, particularly those related to the control of behavior and emotion. The aim of this study was to determine the effectiveness of training puberty (physical and psychological matters in general well being and its dimensions in girl adolescents. This was a quasi-experimental study in which the target population included all girl students at the first grade of high school in Jiroft, Iran. 40 students (20 in the experimental group and 20 in the control group was selected using multi stage sampling method. The experimental group was educated in twelve-90- minute sessions. The content of the educational course included physical signs of puberty, physiologic change in menstrual period, hygiene, nutrition, and psychological changes of puberty. The participants completed the Skehill's general well being questionnaire before and after the intervention. Covariance analysis revealed the efficacy of education on the enhancement of psychological well being and psychological distress reduction. Therefore, it is recommended to implement health educational programs about physical and psychological matters during puberty to elementary and secondary school students to improve their mental health

  1. Generalized product

    OpenAIRE

    Greco, Salvatore; Mesiar, Radko; Rindone, Fabio

    2014-01-01

    Aggregation functions on [0,1] with annihilator 0 can be seen as a generalized product on [0,1]. We study the generalized product on the bipolar scale [–1,1], stressing the axiomatic point of view. Based on newly introduced bipolar properties, such as the bipolar increasingness, bipolar unit element, bipolar idempotent element, several kinds of generalized bipolar product are introduced and studied. A special stress is put on bipolar semicopulas, bipolar quasi-copulas and bipolar copulas.

  2. New ghost-free extensions of general relativity

    International Nuclear Information System (INIS)

    Mann, R.B.

    1989-01-01

    The method of algebraic extension is shown to yield a large class of gravitational theories which are extensions of general relativity. Requiring positivity of energy in the flat-space limit of such theories provides some constraints, but a large set of theories of potential phenomenological interest survives this condition. Explicit examples of such theories include the non-symmetric gravitational theory, algebraically extended Hilbert gravity and a one-parameter family of theories with dynamical torsion. In general such theories do not alter general relativistic post-Newtonian predictions for time delay experiments; rather they alter the non-linearities of the post-Newtonian gravitational potential. Such effects may be probed by measuring periastron shifts, as in the eclipsing binary systems Di Her and As Cam, as well as in the binary pulsar PSR 1913 + 16 (author)

  3. Recombinative generalization of subword units using matching to sample.

    LENUS (Irish Health Repository)

    Mahon, Catherine

    2010-01-01

    The purpose of the current study was to develop and test a computerized matching-to-sample (MTS) protocol to facilitate recombinative generalization of subword units (onsets and rimes) and recognition of novel onset-rime and onset-rime-rime words. In addition, we sought to isolate the key training components necessary for recombinative generalization. Twenty-five literate adults participated. Conditional discrimination training emerged as a crucial training component. These findings support the effectiveness of MTS in facilitating recombinative generalization, particularly when conditional discrimination training with subword units is used.

  4. Determining the distribution of fitness effects using a generalized Beta-Burr distribution.

    Science.gov (United States)

    Joyce, Paul; Abdo, Zaid

    2017-07-12

    In Beisel et al. (2007), a likelihood framework, based on extreme value theory (EVT), was developed for determining the distribution of fitness effects for adaptive mutations. In this paper we extend this framework beyond the extreme distributions and develop a likelihood framework for testing whether or not extreme value theory applies. By making two simple adjustments to the Generalized Pareto Distribution (GPD) we introduce a new simple five parameter probability density function that incorporates nearly every common (continuous) probability model ever used. This means that all of the common models are nested. This has important implications in model selection beyond determining the distribution of fitness effects. However, we demonstrate the use of this distribution utilizing likelihood ratio testing to evaluate alternative distributions to the Gumbel and Weibull domains of attraction of fitness effects. We use a bootstrap strategy, utilizing importance sampling, to determine where in the parameter space will the test be most powerful in detecting deviations from these domains and at what sample size, with focus on small sample sizes (n<20). Our results indicate that the likelihood ratio test is most powerful in detecting deviation from the Gumbel domain when the shape parameters of the model are small while the test is more powerful in detecting deviations from the Weibull domain when these parameters are large. As expected, an increase in sample size improves the power of the test. This improvement is observed to occur quickly with sample size n≥10 in tests related to the Gumbel domain and n≥15 in the case of the Weibull domain. This manuscript is in tribute to the contributions of Dr. Paul Joyce to the areas of Population Genetics, Probability Theory and Mathematical Statistics. A Tribute section is provided at the end that includes Paul's original writing in the first iterations of this manuscript. The Introduction and Alternatives to the GPD sections

  5. A General Analysis of the Impact of Digitization in Microwave Correlation Radiometers

    Directory of Open Access Journals (Sweden)

    Hyuk Park

    2011-06-01

    Full Text Available This study provides a general framework to analyze the effects on correlation radiometers of a generic quantization scheme and sampling process. It reviews, unifies and expands several previous works that focused on these effects separately. In addition, it provides a general theoretical background that allows analyzing any digitization scheme including any number of quantization levels, irregular quantization steps, gain compression, clipping, jitter and skew effects of the sampling period.

  6. Effect of general anesthesia and major versus minor surgery on late postoperative episodic and constant hypoxemia

    DEFF Research Database (Denmark)

    Rosenberg, J; Oturai, P; Erichsen, C J

    1994-01-01

    STUDY OBJECTIVE: To evaluate the relative contribution of general anesthesia alone and in combination with the surgical procedure to the pathogenesis of late postoperative hypoxemia. DESIGN: Open, controlled study. SETTING: University hospital. PATIENTS: 60 patients undergoing major abdominal...... surgery and 16 patients undergoing middle ear surgery, both with comparable general anesthesia. MEASUREMENTS AND MAIN RESULTS: Patients were monitored with continuous pulse oximetry on one preoperative night and the second postoperative night. Significant episodic or constant hypoxemia did not occur...... on the second postoperative night following middle ear surgery and general anesthesia, but severe episodic and constant hypoxemia did occur on the second postoperative after major abdominal surgery and general anesthesia. CONCLUSIONS: General anesthesia in itself is not an important factor in the development...

  7. Adverse Effects of Prolonged Sitting Behavior on the General Health of Office Workers.

    Science.gov (United States)

    Daneshmandi, Hadi; Choobineh, Alireza; Ghaem, Haleh; Karimi, Mehran

    2017-07-01

    Excessive sitting behavior is a risk factor for many adverse health outcomes. This study aimed to survey the prevalence of sitting behavior and its adverse effects among Iranian office workers. This cross-sectional study included 447 Iranian office workers. A two-part questionnaire was used as the data collection tool. The first part surveyed the demographic characteristics and general health of the respondents, while the second part contained the Nordic Musculoskeletal Questionnaire (NMQ) to assess symptoms. Statistical analyses were performed using the Statistical Package for the Social Sciences software using Mann-Whitney U and Chi-square tests and multiple logistic regression analysis. The respondents spent an average of 6.29 hours of an 8-hour working shift in a sitting position. The results showed that 48.8% of the participants did not feel comfortable with their workstations and 73.6% felt exhausted during the workday. Additionally, 6.3% suffered from hypertension, and 11.2% of them reported hyperlipidemia. The results of the NMQ showed that neck (53.5%), lower back (53.2%) and shoulder (51.6%) symptoms were the most prevalent problem among office workers. Based upon a multiple logistic regression, only sex had a significant association with prolonged sitting behavior (odds ratio = 3.084). Our results indicated that long sitting times were associated with exhaustion during the working day, decreased job satisfaction, hypertension, and musculoskeletal disorder symptoms in the shoulders, lower back, thighs, and knees of office workers. Sitting behavior had adverse effects on office workers. Active workstations are therefore recommended to improve working conditions.

  8. General practitioners as supervisors in postgraduate clinical education

    DEFF Research Database (Denmark)

    Wearne, Susan; Dornan, Tim; Teunissen, Pim W.

    2012-01-01

    Context General practice supervisors are said to serve as the cornerstones of general practice postgraduate education and therefore it is important to clearly define their roles and what makes them effective. The commonly used definition of a supervisor is not primarily based on general practice...... with resident doctors that provided a foundation for learning. Residents needed a balance of challenge, usually provided by patients, and support, provided by supervisors. Supervisors established learning environments, assessed residents' learning needs, facilitated learning, monitored the content and process...... of learning and the well-being of residents, and summarised learning in ways that turned 'know that' into 'know how'. Conclusions General practice must be expert in ensuring patients are well cared for 'by proxy' and in giving residents just the right amount of support they need to face the challenges posed...

  9. Calfornia General Plans

    Data.gov (United States)

    California Natural Resource Agency — We undertook creating the first ever seamless statewide General Plan map for California. All county general plans and many city general plans were integrated into 1...

  10. Long-term psychosocial behavioral outcomes in children following anesthesia: A comparison of the effects of general versus regional anesthesia on term infants delivered by elective cesarean section

    Directory of Open Access Journals (Sweden)

    Aouni Alameddine

    2013-01-01

    Full Text Available Background: Data on the effects of general anesthesia on the fetal and neonatal brain are limited. Animal studies demonstrated that anesthetic agents leave their consequences in the form of learning and memory deficits. The effects of propofol on the fetal neurodevelopment are not clear yet. Materials and Methods: This is a telephone-based questionnaire survey that addressed the effect of general anesthesia by propofol during cesarean section at term with no perinatal complications on the psychosocial behavior of children at 8-10 years of age compared with children having same characteristics except for delivery under neuraxial anesthesia using the Pediatric Symptom Checklist as a score. Results: A total of 187 children were born at term between January 1, 2002 and December 31, 2004 with no perinatal distress under induction of general anesthesia by propofol. 66 children (35.3% were lost to follow-up and parents of two children (1.1% refused to participate. A total of 189 children were included in the study: 119 were born by cesarean section under general anesthesia and 70 were born by cesarean section under neuraxial block. The incidence of psychosocial behavior impairment at 8-10 years of age was not found to be affected by the mode of anesthesia during delivery by cesarean section nor by neonatal nor parental characteristics. Conclusion: Exposure to propofol as an induction agent for general anesthesia or cesarean section does not seem to increase the psychosocial behavior disorder development risk at 8-10 years of age.

  11. [Dealing with uncertainty--the hypermodernity of general practice].

    Science.gov (United States)

    Barth, Niklas; Nassehi, Armin; Schneider, Antonius

    2014-01-01

    The general practitioner is fundamentally dealing with uncertainty. On the one hand, we want to demonstrate that uncertainty cannot simply be stipulated as a matter of fact. Instead, we will show that this uncertainty is a performative effect of the primary care setting. On the other hand, we want to point out that the general practitioner's ability to bear uncertainty is a genuinely hypermodern way of productively dealing with uncertainty. Copyright © 2013. Published by Elsevier GmbH.

  12. Effect of Different Doses of Granisetron on Preventing Postoperative Shivering in Patients undergoing Septorhinoplasty under General Anesthesia

    Directory of Open Access Journals (Sweden)

    Reza Movassaghi Gargari

    2017-04-01

    Full Text Available Background: Postoperative shivering is a frequent complication in recovery room after general anesthesia and has been reported in 40-70% of patients undergoing surgery. Postoperative shivering might cause hypoxemia, increase in oxygen consumption, a linear increase in carbon dioxide production, lactic acidosis, and increased intraocular pressure and intracranial pressure. The aim of this study was to compare the effects of different doses of granisetron on preventing postoperative shivering in patients undergoing septorhinoplasty under general anesthesia. Methods: 90 patients aged 18-60 years old with grades Ι or ΙΙ of American Society of Anesthesiologists (ASA physicals classification were allocated to the study. The first group (G1 received Granisetron 1mg Intra Venous (IV before anesthesia induction; the second group (G2 received 3mg Granisetron IV before anesthesia induction and the last group, the control group, received Normal Saline (NS. Three groups were matched regarding age, gender, weight and duration of surgery. Shivering grade and time of operation were recorded in the recovery room. Results: 90 patients scheduled for septorhinoplasty, including 54 men and 36 women, were enrolled to the study.  The mean age of the patients was 28.53 ± 8.62 (18-60 years. The number of the patients suffering from shivering in the recovery room was significantly less in group G2 rather than control group (P=0.006 and also need to therapy was significantly less in this group (G2 compared with the control group (P=0.002.  Conclusion: Prophylactic use of granisetron (3mg, IV can be effective in preventing postoperative shivering following septorhinoplasty.

  13. Generalization and consolidation of scaling laws of potential formation and associated effects in the GAMMA 10 tandem mirror

    International Nuclear Information System (INIS)

    Cho, T.; Hirata, M.; Hojo, H.; Ichimura, M.; Ishii, K.; Itakura, A.; Katanuma, I.; Kohagura, J.; Nakashima, Y.; Saito, T.; Tanaka, S.; Tatematsu, Y.; Yoshikawa, M.; Numakura, T.; Minami, R.; Nagashima, S.; Watanabe, H.; Yoshida, M.; Sakamoto, Y.; Tamano, T.; Yatsu, K.; Miyoshi, S.

    2001-01-01

    Generalized scaling laws for the formation of plasma confining potentials and the associated effectiveness of the potentials produced are systematically investigated to find the physics essentials common to the representative tandem mirror operational modes of GAMMA 10, and to explore novel extended operational modes from the scaling bases constructed. (a) The potential formation scalings are generalized using a novel finding of wider validity of Cohen's strong ECH theory covering the representative modes. (b) The potentials produced, in turn, provide a favourable novel scaling of the increase in the central cell electron temperatures T e with increasing thermal barrier potentials φ b , limited by the available ECH power. The scaling of T e with φ b is well interpreted in terms of the generalized Pastukhov theory of plasma potential confinement. A detailed comparison of the results from several related modified theories is also made. (c) Consolidation of the two major scalings of (a) and (b) in a tandem mirror is carried out by the use of an electron energy balance equation for the first time. In addition, (d) an empirical scaling of φ c with ECH power in the plug region and the central cell densities are studied to discover whether there is the possibility of extending these theoretically well interpreted scaling data to parameters in the future scalable regime. There is also a discussion about numerical scalings in the three dimensional parameter spaces. (author)

  14. Investigating MCTS Modifications in General Video Game Playing

    DEFF Research Database (Denmark)

    Frydenberg, Frederik; Andersen, Kasper; Risi, Sebastian

    2015-01-01

    -style video games. This paper investigates of how well these modifications perform in general video game playing using the general video game AI (GVG-AI) framework and introduces a new MCTS modification called UCT reverse penalty that penalizes the MCTS controller for exploring recently visited children......While Monte Carlo tree search (MCTS) methods have shown promise in a variety of different board games, more complex video games still present significant challenges. Recently, several modifications to the core MCTS algorithm have been proposed with the hope to increase its effectiveness on arcade....... The results of our experiments show that a combination of two MCTS modifications can improve the performance of the vanilla MCTS controller, but the effectiveness of the modifications highly depends on the particular game being played....

  15. Generalized Expression for Polarization Density

    International Nuclear Information System (INIS)

    Wang, Lu; Hahm, T.S.

    2009-01-01

    A general polarization density which consists of classical and neoclassical parts is systematically derived via modern gyrokinetics and bounce-kinetics by employing a phase-space Lagrangian Lie-transform perturbation method. The origins of polarization density are further elucidated. Extending the work on neoclassical polarization for long wavelength compared to ion banana width [M. N. Rosenbluth and F. L. Hinton, Phys. Rev. Lett. 80, 724 (1998)], an analytical formula for the generalized neoclassical polarization including both finite-banana-width (FBW) and finite-Larmor-radius (FLR) effects for arbitrary radial wavelength in comparison to banana width and gyroradius is derived. In additional to the contribution from trapped particles, the contribution of passing particles to the neoclassical polarization is also explicitly calculated. Our analytic expression agrees very well with the previous numerical results for a wide range of radial wavelength.

  16. Is Education Associated with Improvements in General Cognitive Ability, or in Specific Skills?

    Science.gov (United States)

    Ritchie, Stuart J.; Bates, Timothy C.; Deary, Ian J.

    2015-01-01

    Previous research has indicated that education influences cognitive development, but it is unclear what, precisely, is being improved. Here, we tested whether education is associated with cognitive test score improvements via domain-general effects on general cognitive ability ("g"), or via domain-specific effects on particular cognitive…

  17. General Nuclear Medicine

    Science.gov (United States)

    ... Resources Professions Site Index A-Z General Nuclear Medicine Nuclear medicine imaging uses small amounts of radioactive ... of General Nuclear Medicine? What is General Nuclear Medicine? Nuclear medicine is a branch of medical imaging ...

  18. The use of generalized functions and distributions in general relativity

    International Nuclear Information System (INIS)

    Steinbauer, R; Vickers, J A

    2006-01-01

    We review the extent to which one can use classical distribution theory in describing solutions of Einstein's equations. We show that there are a number of physically interesting cases which cannot be treated using distribution theory but require a more general concept. We describe a mathematical theory of nonlinear generalized functions based on Colombeau algebras and show how this may be applied in general relativity. We end by discussing the concept of singularity in general relativity and show that certain solutions with weak singularities may be regarded as distributional solutions of Einstein's equations. (topical review)

  19. Analysis of intense beam instability in a general quadrupole focusing channel with image charge effect

    Energy Technology Data Exchange (ETDEWEB)

    Goswami, A., E-mail: animesh@vecc.gov.in; Sing Babu, P., E-mail: psb@vecc.gov.in; Pandit, V.S., E-mail: pandit@vecc.gov.in

    2016-02-01

    The stability properties of transverse envelopes of mismatched intense continuous charge particle beam propagating in a general quadrupole focusing channel have been investigated in the presence of image charge effect due to a cylindrical conducting pipe. Phase shifts and growth factors of the envelope oscillations in the case of instability are calculated by numerical evaluation of the eigenvalues of linearly perturbed envelope equations for small deviations from the matched beam conditions. A detailed study on the region of instability and its dependence on the system parameters like occupancy of the quadrupole focusing field, syncopation factor, zero current phase advance, beam intensity etc. have been carried out. It has been found that the strength and regions of envelope instability due to the lattice and confluent resonances in the parametric space are affected by the presence of image charge.

  20. Effect of screening and lifestyle counselling on incidence of ischaemic heart disease in general population

    DEFF Research Database (Denmark)

    Jørgensen, Torben; Jacobsen, Rikke Kart; Toft, Ulla

    2014-01-01

    of Copenhagen, Denmark PARTICIPANTS: 59 616 people aged 30-60 years randomised with different age and sex randomisation ratios to an intervention group (n=11 629) and a control group (n=47 987). INTERVENTION: The intervention group was invited for screening, risk assessment, and lifestyle counselling up to four...... of group based lifestyle counselling on smoking cessation, diet, and physical activity. After five years all were invited for a final counselling session. Participants were referred to their general practitioner for medical treatment, if relevant. The control group was not invited for screening. MAIN......OBJECTIVE: To investigate the effect of systematic screening for risk factors for ischaemic heart disease followed by repeated lifestyle counselling on the 10 year development of ischaemic heart disease at a population level. DESIGN: Randomised controlled community based trial. SETTING: Suburbs...

  1. Maximizing the Spread of Influence via Generalized Degree Discount.

    Science.gov (United States)

    Wang, Xiaojie; Zhang, Xue; Zhao, Chengli; Yi, Dongyun

    2016-01-01

    It is a crucial and fundamental issue to identify a small subset of influential spreaders that can control the spreading process in networks. In previous studies, a degree-based heuristic called DegreeDiscount has been shown to effectively identify multiple influential spreaders and has severed as a benchmark method. However, the basic assumption of DegreeDiscount is not adequate, because it treats all the nodes equally without any differences. To consider a general situation in real world networks, a novel heuristic method named GeneralizedDegreeDiscount is proposed in this paper as an effective extension of original method. In our method, the status of a node is defined as a probability of not being influenced by any of its neighbors, and an index generalized discounted degree of one node is presented to measure the expected number of nodes it can influence. Then the spreaders are selected sequentially upon its generalized discounted degree in current network. Empirical experiments are conducted on four real networks, and the results show that the spreaders identified by our approach are more influential than several benchmark methods. Finally, we analyze the relationship between our method and three common degree-based methods.

  2. Generalized Sagnac effect with the ring-laser and other optradiches in the PPN gravitational theory

    International Nuclear Information System (INIS)

    Campbell, S.O.

    1976-01-01

    The scope of study is: The object under study is an experiment to measure the ''dragging of inertial frames'' effect (a post-Newtonian gravitational effect) using two closed-loop optical beams traveling in opposite directions (such a device is denoted an ''optradich''; an example is the ringlaser). A theoretical viewpoint with simple formulas based on the Parametrized Post-Newtonian (PPN) formalism is developed from a study of the literature: the Sagnac effect is generalized to the Post-Newtonian level of approximation. Some differences with a few previous papers are noted and sometimes discussed. Then the formulas are applied to two simple cases. Numerical results are given for an optradich attached to earth, and for optradiches orbiting earth, jupiter, and the sun. The ringlaser, whose further development may make the experiment feasible, is discussed briefly: its basic principle, its potential sensitivity, and some practical considerations. Some aspects of the experiment are also discussed briefly: land optradiches versus orbiting optradiches, Schiff's gyroscope experiment versus the optradich experiment, the present outlook for optradich experiments, and possible scientific benefits of optradich and experiments. Findings and conclusions are the numerical results (see above) are so small that it appears quite doubtful that optradich experiments could verify them in the balance of this century. There seem to be a few interesting effects which Schiff's gyroscope at present cannot measure, but which an assumed ''super'' optradich can measure. Orbiting optradiches and land optradiches may be complementary, but further study is recommended. Despite the discouraging prospects for optradich experiments, efforts should be made to develop sufficiently sensitive optradiches because of the scientific benefits that could be had

  3. Root Effect Haemoglobins in Fish May Greatly Enhance General Oxygen Delivery Relative to Other Vertebrates.

    Directory of Open Access Journals (Sweden)

    Jodie L Rummer

    Full Text Available The teleost fishes represent over half of all extant vertebrates; they occupy nearly every body of water and in doing so, occupy a diverse array of environmental conditions. We propose that their success is related to a unique oxygen (O2 transport system involving their extremely pH-sensitive haemoglobin (Hb. A reduction in pH reduces both Hb-O2 affinity (Bohr effect and carrying capacity (Root effect. This, combined with a large arterial-venous pH change (ΔpHa-v relative to other vertebrates, may greatly enhance tissue oxygen delivery in teleosts (e.g., rainbow trout during stress, beyond that in mammals (e.g., human. We generated oxygen equilibrium curves (OECs at five different CO2 tensions for rainbow trout and determined that, when Hb-O2 saturation is 50% or greater, the change in oxygen partial pressure (ΔPO2 associated with ΔpHa-v can exceed that of the mammalian Bohr effect by at least 3-fold, but as much as 21-fold. Using known ΔpHa-v and assuming a constant arterial-venous PO2 difference (Pa-vO2, Root effect Hbs can enhance O2 release to the tissues by 73.5% in trout; whereas, the Bohr effect alone is responsible for enhancing O2 release by only 1.3% in humans. Disequilibrium states are likely operational in teleosts in vivo, and therefore the ΔpHa-v, and thus enhancement of O2 delivery, could be even larger. Modeling with known Pa-vO2 in fish during exercise and hypoxia indicates that O2 release from the Hb and therefore potentially tissue O2 delivery may double during exercise and triple during some levels of hypoxia. These characteristics may be central to performance of athletic fish species such as salmonids, but may indicate that general tissue oxygen delivery may have been the incipient function of Root effect Hbs in fish, a trait strongly associated with the adaptive radiation of teleosts.

  4. Generalizing minimal supergravity

    International Nuclear Information System (INIS)

    Li, Tianjun; Nanopoulos, Dimitri V.

    2010-01-01

    In Grand Unified Theories (GUTs), the Standard Model (SM) gauge couplings need not be unified at the GUT scale due to the high-dimensional operators. Considering gravity mediated supersymmetry breaking, we study for the first time the generic gauge coupling relations at the GUT scale, and the general gaugino mass relations which are valid from the GUT scale to the electroweak scale at one loop. We define the index k for these relations, which can be calculated in GUTs and can be determined at the Large Hadron Collider and the future International Linear Collider. Thus, we give a concrete definition of the GUT scale in these theories, and suggest a new way to test general GUTs at future experiments. We also discuss five special scenarios with interesting possibilities. With our generic formulae, we present all the GUT-scale gauge coupling relations and all the gaugino mass relations in the SU(5) and SO(10) models, and calculate the corresponding indices k. Especially, the index k is 5/3 in the traditional SU(5) and SO(10) models that have been studied extensively so far. Furthermore, we discuss the field theory realization of the U(1) flux effects on the SM gauge kinetic functions in F-theory GUTs, and calculate their indices k as well.

  5. The Effect of Using an Explicit General Problem Solving Teaching Approach on Elementary Pre-Service Teachers' Ability to Solve Heat Transfer Problems

    Science.gov (United States)

    Mataka, Lloyd M.; Cobern, William W.; Grunert, Megan L.; Mutambuki, Jacinta; Akom, George

    2014-01-01

    This study investigate the effectiveness of adding an "explicit general problem solving teaching strategy" (EGPS) to guided inquiry (GI) on pre-service elementary school teachers' ability to solve heat transfer problems. The pre-service elementary teachers in this study were enrolled in two sections of a chemistry course for pre-service…

  6. The Effects of a Self-Monitoring Package on Homework Completion and Accuracy of Students with Disabilities in an Inclusive General Education Classroom

    Science.gov (United States)

    Falkenberg, Carol Ann; Barbetta, Patricia M.

    2013-01-01

    This study used a multiple baseline design across subjects to investigate the effects of a self-monitoring package on the math and spelling homework completion and accuracy rates of four fourth-grade students (two boys and two girls) with disabilities in an inclusive general education classroom. Throughout baseline and intervention, participants…

  7. General Ultrasound Imaging

    Medline Plus

    Full Text Available ... News Physician Resources Professions Site Index A-Z General Ultrasound Ultrasound imaging uses sound waves to produce ... the limitations of General Ultrasound Imaging? What is General Ultrasound Imaging? Ultrasound is safe and painless, and ...

  8. Collaborative care for depression in general practice

    DEFF Research Database (Denmark)

    Brinck-Claussen, Ursula Ødum; Curth, Nadja Kehler; Davidsen, Annette Sofie

    2017-01-01

    Background: Depression is a common illness with great human costs and a significant burden on the public economy. Previous studies have indicated that collaborative care (CC) has a positive effect on symptoms when provided to people with depression, but CC has not yet been applied in a Danish...... context. We therefore developed a model for CC (the Collabri model) to treat people with depression in general practice in Denmark. Since systematic identification of patients is an “active ingredient” in CC and some literature suggests case finding as the best alternative to standard detection, the two...... detection methods are examined as part of the study. The aim is to investigate if treatment according to the Collabri model has an effect on depression symptoms when provided to people with depression in general practice in Denmark, and to examine if case finding is a better method to detect depression...

  9. [Ishemic-reperfusion syndrome prophylaxis in general hypothermia in experiment].

    Science.gov (United States)

    Zubkov, V I; Khytryĭ, H P; Luk'ianchuk, V D; Shalamaĭ, A S

    2009-05-01

    The influence of general supercooling on rats were studied. The action of corvitin and pentoxiphillin on the prooxidant-antioxidant homeostasis for conditions of general supercooling were analysed. On the based of investigations results analysis of lipids peroxide oxidation indexes and antioxidant protection system in animals it were established, that corvitin in difference of pentoxiphillin give more significant protectory effect in conditions of ishemic-reperfusion syndrome.

  10. Effects of Low Anisotropy on Generalized Ghost Dark Energy in Galileon Gravity

    Science.gov (United States)

    Hossienkhani, H.; Fayaz, V.; Jafari, A.; Yousefi, H.

    2018-04-01

    The definition of the Galileon gravity form is extended to the Brans-Dicke theory. Given, the framework of the Galileon theory, the generalized ghost dark energy model in an anisotropic universe is investigated. We study the cosmological implications of this model. In particular, we obtain the equation of state and the deceleration parameters and a differential equation governing the evolution of this dark energy in Bianchi type I model. We also probe observational constraints by using the latest observational data on the generalized ghost dark energy models as the unification of dark matter and dark energy. In order to do so, we focus on observational determinations of the Hubble expansion rate (namely, the expansion history) H(z). As a result, we show the influence of the anisotropy (although low) on the evolution of the universe in the statefinder diagrams for Galileon gravity.

  11. Loop transfer recovery for general observer architecture

    DEFF Research Database (Denmark)

    Niemann, Hans Henrik; Søgaard-Andersen, Per; Stoustrup, Jakob

    1991-01-01

    A general and concise formulation is given of the loop transfer recovery (LTR) design problem based on recovery errors. Three types of recovery errors are treated: open loop recovery, sensitivity recovery and input-output recovery errors. The three corresponding versions of the asymptotic recovery...... recovery cases. This general recovery formulation covers all known observer based compensator types as special cases. The conditions given in this setting are effectively the aim of all known LTR design methods. The recovery formulation is interpreted in terms of a modelmatching problem as well, which...... is examined by means of the Q-parametrization. It is shown how the general controller obtained by the Q-parametrization can be written as a Luenberger observer based controller. In all cases, n controller states suffice to achieve recovery. The compensators are characterized for errors both on the input...

  12. Prevalence and Factors Affecting Dysmenorrhea in Female University Students: Effect on General Comfort Level.

    Science.gov (United States)

    Aktaş, Demet

    2015-08-01

    The purpose of this study was to investigate the prevalence and the affecting factors of dysmenorrhea and its effects on overall comfort among female university students. This was a cross-sectional study. The research was carried out between October and November 2013 at a university in Ankara. This study was conducted with 200 female students. The data were analyzed using frequencies, means, SD, χ(2) tests, independent t tests and analysis of variance. Data were collected using an interview questionnaire, the visual analog scale (VAS) and the General Comfort Questionnaire. The mean age of students in this study group was 20.85 ± 2.15 years. The prevalence of dysmenorrhea in the students was 84%. The mean severity of pain was 5.78 ± 2.45 on the VAS. The present study found that 45.8% of female students experienced moderate menstrual pain and the most common co-occurring symptoms were irritability (34.6%) and fatigue (21.5%). One-fourth of the students with dysmenorrhea consulted the advice of a physician and the most commonly used methods for pain were analgesics (69%), heat application (56.5%), and rest (71.4%). Family history of dysmenorrhea, education about menstruation, and frequency of menstrual cycle were identified as important factors in the development of dysmenorrhea (p dysmenorrhea (2.57 ± 0.25) was lower than that of students without the condition (2.65 ± 0.23). Also, use of the methods for management of dysmenorrhea was found to increase students' general comfort levels. Therefore, it is important for nurses to educate and advise adolescents and young women about dysmenorrhea. Copyright © 2015 American Society for Pain Management Nursing. Published by Elsevier Inc. All rights reserved.

  13. [Acceptance of generic prescribing in general practice: effect of patient education and reference prices].

    Science.gov (United States)

    Vallès, J A; Barreiro, M; Cereza, G; Ferro, J J; Martínez, M J; Cucurull, E; Barceló, E

    2002-01-01

    To assess patient acceptance of the substitution of brand-name drugs for generic equivalents in the context of repeat prescriptions for chronic diseases. A prospective multicenter study of drug use was performed. Of the 31 centers included in the study, 8 were randomized to the intervention group and 23 to the control group. For 1 year, patients in the intervention group who visited the center to collect repeat prescriptions received verbal and written information on the advantages and disadvantages of generic and brand name drugs. Data on the number of patients taking brand-name drugs for which generic equivalents were available, as well as the reasons and variables related to refusal of generic drugs (age, gender, education, primary care centre, general practitioner, type of drug and total number of repeat prescriptions) were collected. The percentage of generic drugs among the total number of drugs prescribed was calculated at 2-monthly intervals. A total of 98.9% of the 4620 patients in the intervention group agreed to change to a generic formulation. The percentage of patients accepting generic drugs was significantly associated with the primary care centre, the class of drug, doctors' influence, and patient satisfaction with the drug. Generic prescriptions represented 5.9% in the intervention practices compared with 2.8% in controls. After the intervention, and before the application of reference prices, the percentages were 6.7% and 3.9%, respectively. Immediately after application of the reference prices, the percentages were 8.6% and 6.3%, respectively. Direct patient education is an effective strategy in increasing the prescription of generic equivalents. General practitioners' motivation and knowledge of generic drugs influenced their use. The application of reference prices increased the use of generic equivalents.

  14. The general use of the time-temperature-pressure superposition principle

    DEFF Research Database (Denmark)

    Rasmussen, Henrik Koblitz

    This note is a supplement to Dynamic of Polymeric Liquids (DPL) section 3.6(a). DPL do only concern material functions and only the effect of the temperature on these. This is a short introduction to the general use of the time-temperature-pressure superposition principle.......This note is a supplement to Dynamic of Polymeric Liquids (DPL) section 3.6(a). DPL do only concern material functions and only the effect of the temperature on these. This is a short introduction to the general use of the time-temperature-pressure superposition principle....

  15. Relativistic generalization of strong plasma turbulence

    International Nuclear Information System (INIS)

    Chian, A.C.-L.

    1982-01-01

    Two fundamental electrostatic modes of an unmagnetized plasma, namely, ion acoustic mode and Langumir mode are studied. Previous theories are generalized to include the effect of relativistic mass variations. The existence of relativistic ion acoustic solitons is demonstrated. In addition, it is shown that simple, relativistic Langumir solitons do not exist in a infinite plasma. (L.C.) [pt

  16. Effect of General Anesthesia in Infancy on Long-Term Recognition Memory in Humans and Rats

    Science.gov (United States)

    Stratmann, Greg; Lee, Joshua; Sall, Jeffrey W; Lee, Bradley H; Alvi, Rehan S; Shih, Jennifer; Rowe, Allison M; Ramage, Tatiana M; Chang, Flora L; Alexander, Terri G; Lempert, David K; Lin, Nan; Siu, Kasey H; Elphick, Sophie A; Wong, Alice; Schnair, Caitlin I; Vu, Alexander F; Chan, John T; Zai, Huizhen; Wong, Michelle K; Anthony, Amanda M; Barbour, Kyle C; Ben-Tzur, Dana; Kazarian, Natalie E; Lee, Joyce YY; Shen, Jay R; Liu, Eric; Behniwal, Gurbir S; Lammers, Cathy R; Quinones, Zoel; Aggarwal, Anuj; Cedars, Elizabeth; Yonelinas, Andrew P; Ghetti, Simona

    2014-01-01

    Anesthesia in infancy impairs performance in recognition memory tasks in mammalian animals, but it is unknown if this occurs in humans. Successful recognition can be based on stimulus familiarity or recollection of event details. Several brain structures involved in recollection are affected by anesthesia-induced neurodegeneration in animals. Therefore, we hypothesized that anesthesia in infancy impairs recollection later in life in humans and rats. Twenty eight children ages 6–11 who had undergone a procedure requiring general anesthesia before age 1 were compared with 28 age- and gender-matched children who had not undergone anesthesia. Recollection and familiarity were assessed in an object recognition memory test using receiver operator characteristic analysis. In addition, IQ and Child Behavior Checklist scores were assessed. In parallel, thirty three 7-day-old rats were randomized to receive anesthesia or sham anesthesia. Over 10 months, recollection and familiarity were assessed using an odor recognition test. We found that anesthetized children had significantly lower recollection scores and were impaired at recollecting associative information compared with controls. Familiarity, IQ, and Child Behavior Checklist scores were not different between groups. In rats, anesthetized subjects had significantly lower recollection scores than controls while familiarity was unaffected. Rats that had undergone tissue injury during anesthesia had similar recollection indices as rats that had been anesthetized without tissue injury. These findings suggest that general anesthesia in infancy impairs recollection later in life in humans and rats. In rats, this effect is independent of underlying disease or tissue injury. PMID:24910347

  17. No mediating effects of glycemic control and inflammation on the association between vitamin D and lung function in the general population.

    Science.gov (United States)

    Kaul, Anne; Gläser, Sven; Hannemann, Anke; Stubbe, Beate; Felix, Stefan B; Nauck, Matthias; Ewert, Ralf; Friedrich, Nele

    2017-04-01

    Vitamin D deficiency is discussed to be associated with lung health. While former studies focused on subjects suffering from pulmonary diseases, we aimed to investigate the association of 25-hydroxy vitamin D [25(OH)D] with lung function in the general population and examined whether mediating effects of inflammation, glycemic control or renal function exist. 1404 participants from the Study of Health in Pomerania with pulmonary function testing assessed by expiratory volume in 1 s (FEV 1 ), forced vital capacity (FVC), total lung capacity and Krogh index were used. Adjusted analysis of variance, linear regression models and mediation analyses were performed. Significant positive associations between 25(OH)D levels and FEV 1 , FVC and Krogh index were found. Mediator analyses revealed no mediating effect of inflammation (fibrinogen), glycemic control (HbA1c) or renal function (eGFR) on associations with FEV 1 or FVC. With respect to Krogh-Index, the association to 25(OH)D was slightly mediated by fibrinogen with a proportion mediated of 9.7%. Significant positive associations of 25(OH)D with lung function were revealed in a general population. The proposed mediating effects of inflammation, glycemic control and renal function on these relations were not confirmed. Further studies examining the causality of the association between 25(OH)D and lung function are necessary. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. The General Factor of Personality: Ten Years After

    Directory of Open Access Journals (Sweden)

    Janek Musek

    2017-05-01

    Full Text Available According to the empirical and theoretical research in past ten years, the General Factor of Personality (GFP was interpreted as the highest-order (most general personality dimension, which occupies the apex of the structural hierarchy of personality traits. Thus, the GFP is the central concept in the new structural paradigm of personality (the Pyramidal Model of Personality. In the majority of the studies, the GFP was conceptualized as a general factor with substantial psychological (cognitive and behavioural content reflecting the general social and personal adjustment or effectiveness. The alternative explanations of the GFP emphasize the role of the semantic factors, response styles and other biases. This study reviews the main results of the GFP research including the nature, the biological bases, the strength and cultural universality of GFP, its relations to intelligence and other prominent psychological variables, and its predictive power and practical importance.

  19. The Effect of EMDR and CBT on Low Self-esteem in a General Psychiatric Population: A Randomized Controlled Trial.

    Science.gov (United States)

    Griffioen, Brecht T; van der Vegt, Anna A; de Groot, Izaäk W; de Jongh, Ad

    2017-01-01

    Although low self-esteem has been found to be an important factor in the development and maintenance of psychopathology, surprisingly little is known about its treatment. This study investigated the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy and Cognitive Behavioural Therapy (CBT), regarding their capacities in enhancing self-esteem in a general psychiatric secondary health care population. A randomized controlled trial with two parallel groups was used. Participants were randomly allocated to either 10 weekly sessions of EMDR ( n = 15) or CBT ( n = 15). They were assessed pre-treatment, after each session, post treatment and at 3 months follow-up on self-esteem (Rosenberg Self-esteem Scale and Credibility of Core Beliefs), psychological symptoms (Brief Symptom Inventory), social anxiety, and social interaction (Inventory of Interpersonal Situations) (IIS). The data were analyzed using repeated measures ANOVA for the complete cases ( n = 19) and intention-to-treat ( n = 30) to examine differences over time and between conditions. Both groups, EMDR as well as CBT, showed significant improvements on self-esteem, increasing two standard deviations on the main parameter (RSES). Furthermore, the results showed significant reductions in general psychiatric symptoms. The effects were maintained at 3 months follow-up. No between-group differences could be detected. Although the small sample requires to exercise caution in the interpretation of the findings, the results suggest that, when offering an adequate number of sessions, both EMDR and CBT have the potential to be effective treatments for patients with low self-esteem and a wide range of comorbid psychiatric conditions. This study was registered at www.trialregister.nl with identifier NTR4611.

  20. The Effect of EMDR and CBT on Low Self-esteem in a General Psychiatric Population: A Randomized Controlled Trial

    Directory of Open Access Journals (Sweden)

    Brecht T. Griffioen

    2017-11-01

    Full Text Available Although low self-esteem has been found to be an important factor in the development and maintenance of psychopathology, surprisingly little is known about its treatment. This study investigated the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR therapy and Cognitive Behavioural Therapy (CBT, regarding their capacities in enhancing self-esteem in a general psychiatric secondary health care population. A randomized controlled trial with two parallel groups was used. Participants were randomly allocated to either 10 weekly sessions of EMDR (n = 15 or CBT (n = 15. They were assessed pre-treatment, after each session, post treatment and at 3 months follow-up on self-esteem (Rosenberg Self-esteem Scale and Credibility of Core Beliefs, psychological symptoms (Brief Symptom Inventory, social anxiety, and social interaction (Inventory of Interpersonal Situations (IIS. The data were analyzed using repeated measures ANOVA for the complete cases (n = 19 and intention-to-treat (n = 30 to examine differences over time and between conditions. Both groups, EMDR as well as CBT, showed significant improvements on self-esteem, increasing two standard deviations on the main parameter (RSES. Furthermore, the results showed significant reductions in general psychiatric symptoms. The effects were maintained at 3 months follow-up. No between-group differences could be detected. Although the small sample requires to exercise caution in the interpretation of the findings, the results suggest that, when offering an adequate number of sessions, both EMDR and CBT have the potential to be effective treatments for patients with low self-esteem and a wide range of comorbid psychiatric conditions. This study was registered at www.trialregister.nl with identifier NTR4611.

  1. Synchronization of generalized Henon map via backstepping design

    International Nuclear Information System (INIS)

    Huang Lilian; Wang Mao; Feng Rupeng

    2005-01-01

    This paper proposes a backstepping method to resolve the synchronization of discrete-time chaotic systems. The proposed scheme offers systematic design method for the synchronization of a class of discrete-time hyper-chaotic systems, which implies much complicated high-order chaotic systems can be used to improve the security in chaos communications. A well-known chaotic systems: generalized Henon map is considered as illustrative example to demonstrate the general applicability of backstepping design. Numerical simulations verify the effectiveness of the approach

  2. ADHD medication prescription: effects of child, sibling, parent and general practice characteristics.

    NARCIS (Netherlands)

    Heins, M.J.; Bruggers, I.; Dijk, L. van; Korevaar, J.C.

    2016-01-01

    Many children receive attention-deficit hyperactivity disorder (ADHD) medication, but factors that determine medication prescription are largely unknown. This study aimed to determine the relative impact of factors on the child, family and general practitioner (GP) practice level on ADHD medication

  3. The effect of direct referral for fast CT scan in early lung cancer detection in general practice. A clinical, cluster-randomised trial.

    Science.gov (United States)

    Guldbrandt, Louise Mahncke

    2015-03-01

    This PhD thesis is based on the project "The effect of direct referral for fast CT scan in early lung cancer detection in general practice. A clinical, cluster-randomised trial", performed in Denmark in 2010-2013. The thesis includes four papers and focuses on early lung cancer diagnostics in general practice. A total of 4200 new cases of lung cancer are diagnosed in Denmark annually. The stage of the disease is an important prognostic factor; thus, the opportunity for curative treatment declines with more advanced tumour stage. Lung cancer patients in Denmark (like in the UK) have a poorer prognosis than lung cancer patients in other European countries. One explanation could be delayed diagnosis. A fast-track pathway was therefore introduced in an attempt to expedite the diagnosis of cancer. However, it seems that not all patients can be diagnosed through this pathway. In order to ensure fast and early lung cancer diagnosis, it is crucial to examine the initial diagnostic process in general and the role general practice plays in lung cancer diagnostics in particular. The specific areas of investigation include the pathways to diagnosis, the characteristics of patients who are at special risk of delayed diagnosis and the level of prediagnostic activity in general practice. A chest radiograph is often the first choice in the investigation of lung cancer. Unfortunately, radiographs are less suitable for central and small tumours. Low-dose computer tomography (LDCT), however, has a high sensitivity for lung cancer which implies that it can be used to detect patients with localised, potentially curable disease. The aim of this thesis was to increase our knowledge of the initial stages of lung cancer diagnostics in general practice. The thesis also examined the effect of a direct referral from general practice to an additional diagnostic test, the LDCT. The aims of this thesis were: 1) To describe Danish patients' pathways to the diagnosis of lung cancer in general and

  4. The Protective Effects of Family Support on the Relationship between Official Intervention and General Delinquency across the Life Course.

    Science.gov (United States)

    Dong, Beidi; Krohn, Marvin D

    2017-03-01

    Previous research on the labeling perspective has identified mediational processes and the long-term effects of official intervention in the life course. However, it is not yet clear what factors may moderate the relationship between labeling and subsequent offending. The current study integrates Cullen's (1994) social support theory to examine how family social support conditions the criminogenic, stigmatizing effects of official intervention on delinquency and whether such protective effects vary by developmental stage. Using longitudinal data from the Rochester Youth Development Study, we estimated negative binomial regression models to investigate the relationships between police arrest, family social support, and criminal offending during both adolescence and young adulthood. Police arrest is a significant predictor of self-reported delinquency in both the adolescent and adult models. Expressive family support exhibits main effects in the adolescent models; instrumental family support exhibits main effects at both developmental stages. Additionally, instrumental family support diminishes some of the predicted adverse effects of official intervention in adulthood. Perception of family support can be critical in reducing general delinquency as well as buffering against the adverse effects of official intervention on subsequent offending. Policies and programs that work with families subsequent to a criminal justice intervention should emphasize the importance of providing a supportive environment for those who are labeled.

  5. Generality and specificity in the effects of musical expertise on perception and cognition.

    Science.gov (United States)

    Carey, Daniel; Rosen, Stuart; Krishnan, Saloni; Pearce, Marcus T; Shepherd, Alex; Aydelott, Jennifer; Dick, Frederic

    2015-04-01

    Performing musicians invest thousands of hours becoming experts in a range of perceptual, attentional, and cognitive skills. The duration and intensity of musicians' training - far greater than that of most educational or rehabilitation programs - provides a useful model to test the extent to which skills acquired in one particular context (music) generalize to different domains. Here, we asked whether the instrument-specific and more instrument-general skills acquired during professional violinists' and pianists' training would generalize to superior performance on a wide range of analogous (largely non-musical) skills, when compared to closely matched non-musicians. Violinists and pianists outperformed non-musicians on fine-grained auditory psychophysical measures, but surprisingly did not differ from each other, despite the different demands of their instruments. Musician groups did differ on a tuning system perception task: violinists showed clearest biases towards the tuning system specific to their instrument, suggesting that long-term experience leads to selective perceptual benefits given a training-relevant context. However, we found only weak evidence of group differences in non-musical skills, with musicians differing marginally in one measure of sustained auditory attention, but not significantly on auditory scene analysis or multi-modal sequencing measures. Further, regression analyses showed that this sustained auditory attention metric predicted more variance in one auditory psychophysical measure than did musical expertise. Our findings suggest that specific musical expertise may yield distinct perceptual outcomes within contexts close to the area of training. Generalization of expertise to relevant cognitive domains may be less clear, particularly where the task context is non-musical. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Generalized formula for electron emission taking account of the polaron effect

    Science.gov (United States)

    Barengolts, Yu A.; Beril, S. I.; Barengolts, S. A.

    2018-01-01

    A generalized formula is derived for the electron emission current as a function of temperature, field, and electron work function in a metal-dielectric system that takes account of the quantum nature of the image forces. In deriving the formula, the Fermi-Dirac distribution for electrons in a metal and the quantum potential of the image obtained in the context of electron polaron theory are used.

  7. General Anesthesia Inhibits the Activity of the "Glymphatic System".

    Science.gov (United States)

    Gakuba, Clement; Gaberel, Thomas; Goursaud, Suzanne; Bourges, Jennifer; Di Palma, Camille; Quenault, Aurélien; de Lizarrondo, Sara Martinez; Vivien, Denis; Gauberti, Maxime

    2018-01-01

    INTRODUCTION: According to the "glymphatic system" hypothesis, brain waste clearance is mediated by a continuous replacement of the interstitial milieu by a bulk flow of cerebrospinal fluid (CSF). Previous reports suggested that this cerebral CSF circulation is only active during general anesthesia or sleep, an effect mediated by the dilatation of the extracellular space. Given the controversies regarding the plausibility of this phenomenon and the limitations of currently available methods to image the glymphatic system, we developed original whole-brain in vivo imaging methods to investigate the effects of general anesthesia on the brain CSF circulation. METHODS: We used magnetic resonance imaging (MRI) and near-infrared fluorescence imaging (NIRF) after injection of a paramagnetic contrast agent or a fluorescent dye in the cisterna magna, in order to investigate the impact of general anesthesia (isoflurane, ketamine or ketamine/xylazine) on the intracranial CSF circulation in mice. RESULTS: In vivo imaging allowed us to image CSF flow in awake and anesthetized mice and confirmed the existence of a brain-wide CSF circulation. Contrary to what was initially thought, we demonstrated that the parenchymal CSF circulation is mainly active during wakefulness and significantly impaired during general anesthesia. This effect was especially significant when high doses of anesthetic agent were used (3% isoflurane). These results were consistent across the different anesthesia regimens and imaging modalities. Moreover, we failed to detect a significant change in the brain extracellular water volume using diffusion weighted imaging in awake and anesthetized mice. CONCLUSION: The parenchymal diffusion of small molecular weight compounds from the CSF is active during wakefulness. General anesthesia has a negative impact on the intracranial CSF circulation, especially when using a high dose of anesthetic agent.

  8. Effect of scaling and root planing on blood counts in patients with chronic generalized periodontitis

    Directory of Open Access Journals (Sweden)

    Devinder Singh Kalsi

    2017-01-01

    Full Text Available Background: Many systemic diseases have been implicated as risk factors in periodontal disease. Studies suggest that periodontal infection can adversely affect systemic health; by inference periodontal disease will also have an effect on blood values, but the data available is not conclusive. Aim: This clinical study was designed to evaluate the effect of treatment of plaque induced periodontitis on commonly assessed blood parameters. Materials and Method: 37 males and 31 females aged between 20 and 50 years in good general health but suffering from plaque induced chronic periodontitis were selected for the study. The selected patients were assessed for ESR, TLC, PMN count, lymphocyte count from DLC, HB, BT and their periodontal condition before the start of the study. SCRP was carried out and patients were reassessed for the same clinical and hematological parameters 21 days after the periodontal therapy (SCRP. Results: A highly significant reduction in the counts of PMNs and the values of ESI was seen after SCRP. Furthermore a significant reduction in TLC, lymphocytes count, and BT and a non significant decrease in Hb were also observed. Conclusion: SCRP done in patients of chronic periodontitis has a considerable affect on the assessed blood parameters.

  9. General relativity

    International Nuclear Information System (INIS)

    Kenyon, I.R.

    1990-01-01

    General relativity is discussed in this book at a level appropriate to undergraduate students of physics and astronomy. It describes concepts and experimental results, and provides a succinct account of the formalism. A brief review of special relativity is followed by a discussion of the equivalence principle and its implications. Other topics covered include the concepts of curvature and the Schwarzschild metric, test of the general theory, black holes and their properties, gravitational radiation and methods for its detection, the impact of general relativity on cosmology, and the continuing search for a quantum theory of gravity. (author)

  10. General Methods for Evolutionary Quantitative Genetic Inference from Generalized Mixed Models.

    Science.gov (United States)

    de Villemereuil, Pierre; Schielzeth, Holger; Nakagawa, Shinichi; Morrissey, Michael

    2016-11-01

    Methods for inference and interpretation of evolutionary quantitative genetic parameters, and for prediction of the response to selection, are best developed for traits with normal distributions. Many traits of evolutionary interest, including many life history and behavioral traits, have inherently nonnormal distributions. The generalized linear mixed model (GLMM) framework has become a widely used tool for estimating quantitative genetic parameters for nonnormal traits. However, whereas GLMMs provide inference on a statistically convenient latent scale, it is often desirable to express quantitative genetic parameters on the scale upon which traits are measured. The parameters of fitted GLMMs, despite being on a latent scale, fully determine all quantities of potential interest on the scale on which traits are expressed. We provide expressions for deriving each of such quantities, including population means, phenotypic (co)variances, variance components including additive genetic (co)variances, and parameters such as heritability. We demonstrate that fixed effects have a strong impact on those parameters and show how to deal with this by averaging or integrating over fixed effects. The expressions require integration of quantities determined by the link function, over distributions of latent values. In general cases, the required integrals must be solved numerically, but efficient methods are available and we provide an implementation in an R package, QGglmm. We show that known formulas for quantities such as heritability of traits with binomial and Poisson distributions are special cases of our expressions. Additionally, we show how fitted GLMM can be incorporated into existing methods for predicting evolutionary trajectories. We demonstrate the accuracy of the resulting method for evolutionary prediction by simulation and apply our approach to data from a wild pedigreed vertebrate population. Copyright © 2016 de Villemereuil et al.

  11. Decimated Input Ensembles for Improved Generalization

    Science.gov (United States)

    Tumer, Kagan; Oza, Nikunj C.; Norvig, Peter (Technical Monitor)

    1999-01-01

    Recently, many researchers have demonstrated that using classifier ensembles (e.g., averaging the outputs of multiple classifiers before reaching a classification decision) leads to improved performance for many difficult generalization problems. However, in many domains there are serious impediments to such "turnkey" classification accuracy improvements. Most notable among these is the deleterious effect of highly correlated classifiers on the ensemble performance. One particular solution to this problem is generating "new" training sets by sampling the original one. However, with finite number of patterns, this causes a reduction in the training patterns each classifier sees, often resulting in considerably worsened generalization performance (particularly for high dimensional data domains) for each individual classifier. Generally, this drop in the accuracy of the individual classifier performance more than offsets any potential gains due to combining, unless diversity among classifiers is actively promoted. In this work, we introduce a method that: (1) reduces the correlation among the classifiers; (2) reduces the dimensionality of the data, thus lessening the impact of the 'curse of dimensionality'; and (3) improves the classification performance of the ensemble.

  12. Linear relativistic gyrokinetic equation in general magnetically confined plasmas

    International Nuclear Information System (INIS)

    Tsai, S.T.; Van Dam, J.W.; Chen, L.

    1983-08-01

    The gyrokinetic formalism for linear electromagnetic waves of arbitrary frequency in general magnetic-field configurations is extended to include full relativistic effects. The derivation employs the small adiabaticity parameter rho/L 0 where rho is the Larmor radius and L 0 the equilibrium scale length. The effects of the plasma and magnetic field inhomogeneities and finite Larmor-radii effects are also contained

  13. The Effect of a Surgical Skills Course on Confidence Levels of Rural General Practitioners: An Observational Study.

    Science.gov (United States)

    Byrd, Pippa; Ward, Olga; Hamdorf, Jeffrey

    2016-10-01

    Objective  To investigate the effect of a short surgical skills course on general practitioners' confidence levels to perform procedural skills. Design  Prospective observational study. Setting  The Clinical Evaluation and Training Centre, a practical skills-based educational facility, at The University of Western Australia. Participants  Medical practitioners who participated in these courses. Nurses, physiotherapists, and medical students were excluded. The response rate was 61% with 61 participants providing 788 responses for pre- and postcourse confidence levels regarding various surgical skills. Intervention  One- to two-day surgical skills courses consisting of presentations, demonstrations, and practical stations, facilitated by specialists. Main Outcome Measures  A two-page precourse and postcourse questionnaire was administered to medical practitioners on the day. Participants rated their confidence levels to perform skills addressed during the course on a 4-point Likert scale. Results  Of the 788 responses regarding confidence levels, 621 were rated as improved postcourse, 163 were rated as no change, and 4 were rated as lower postcourse. Seven of the courses showed a 25% median increase in confidence levels, and one course demonstrated a 50% median increase. All courses showed statistically significant results ( p  skills course resulted in a statistically significant improvement in the confidence levels of rural general practitioners to perform these skills.

  14. Effect of esmolol infusion on myocardial oxygen consumption during extubation and quality of recovery in elderly patients undergoing general anesthesia: randomized, double blinded, clinical trial

    Directory of Open Access Journals (Sweden)

    Sherif A. ELokda

    2015-04-01

    Conclusions: Esmolol is a safe, effective and well-tolerated drug that can be used in elderly patients undergoing general anesthesia to reduce the myocardial oxygen consumption and improve the quality of recovery.

  15. General Relativity

    CERN Document Server

    Straumann, Norbert

    2013-01-01

    This book provides a completely revised and expanded version of the previous classic edition ‘General Relativity and Relativistic Astrophysics’. In Part I the foundations of general relativity are thoroughly developed, while Part II is devoted to tests of general relativity and many of its applications. Binary pulsars – our best laboratories for general relativity – are studied in considerable detail. An introduction to gravitational lensing theory is included as well, so as to make the current literature on the subject accessible to readers. Considerable attention is devoted to the study of compact objects, especially to black holes. This includes a detailed derivation of the Kerr solution, Israel’s proof of his uniqueness theorem, and a derivation of the basic laws of black hole physics. Part II ends with Witten’s proof of the positive energy theorem, which is presented in detail, together with the required tools on spin structures and spinor analysis. In Part III, all of the differential geomet...

  16. Motivation towards extracurricular activities and motivation at school: A test of the generalization effect hypothesis.

    Science.gov (United States)

    Denault, Anne-Sophie; Guay, Frédéric

    2017-01-01

    Participation in extracurricular activities is a promising avenue for enhancing students' school motivation. Using self-determination theory (Deci & Ryan, 2000), the goal of this study was to test a serial multiple mediator model. In this model, students' perceptions of autonomy support from their extracurricular activity leader predicted their activity-based intrinsic and identified regulations. In turn, these regulations predicted their school-based intrinsic and identified regulations during the same school year. Finally, these regulations predicted their school-based intrinsic and identified regulations one year later. A total of 276 youths (54% girls) from disadvantaged neighborhoods were surveyed over two waves of data collection. The proposed mediation model was supported for both types of regulation. These results highlight the generalization effects of motivation from the extracurricular activity context to the school context. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  17. Duration of Sexual Harassment and Generalized Harassment in the Workplace Over Ten Years: Effects on Deleterious Drinking Outcomes

    Science.gov (United States)

    McGinley, Meredith; Richman, Judith A.; Rospenda, Kathleen M.

    2012-01-01

    While harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a ten year longitudinal mail survey, university employees (N = 2265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gender, age, and race) predicted the shape of the trajectories and likelihood of class membership. As hypothesized, membership in the chronic harassment classes was linked to future problematic drinking, even after controlling for previous drinking. PMID:21745045

  18. Duration of sexual harassment and generalized harassment in the workplace over ten years: effects on deleterious drinking outcomes.

    Science.gov (United States)

    McGinley, Meredith; Richman, Judith A; Rospenda, Kathleen M

    2011-01-01

    Although harassment in the workplace has been linked to deleterious drinking outcomes, researchers have yet to examine the long-term effects of chronic workplace harassment. During a 10-year longitudinal mail survey, university employees (N = 2,265) were administered measures of sexual harassment, generalized workplace harassment, and problematic drinking. Using growth mixture modeling, two latent classes of workplace harassment emerged: infrequent and chronic. Demographic characteristics (gender, age, and race) predicted the shape of the trajectories and likelihood of class membership. As hypothesized, membership in the chronic harassment classes was linked to future problematic drinking, even after controlling for previous drinking.

  19. Investigation of radiation effects in Hiroshima and Nagasaki using a general Monte Carlo-discrete ordinates coupling scheme

    International Nuclear Information System (INIS)

    Cramer, S.N.; Slater, C.O.

    1990-01-01

    A general adjoint Monte Carlo-forward discrete ordinates radiation transport calculational scheme has been created to study the effects of the radiation environment in Hiroshima and Nagasaki due to the bombing of these two cities. Various such studies for comparison with physical data have progressed since the end of World War II with advancements in computing machinery and computational methods. These efforts have intensified in the last several years with the U.S.-Japan joint reassessment of nuclear weapons dosimetry in Hiroshima and Nagasaki. Three principal areas of investigation are: (1) to determine by experiment and calculation the neutron and gamma-ray energy and angular spectra and total yield of the two weapons; (2) using these weapons descriptions as source terms, to compute radiation effects at several locations in the two cities for comparison with experimental data collected at various times after the bombings and thus validate the source terms; and (3) to compute radiation fields at the known locations of fatalities and surviving individuals at the time of the bombings and thus establish an absolute cause-and-effect relationship between the radiation received and the resulting injuries to these individuals and any of their descendants as indicated by their medical records. It is in connection with the second and third items, the determination of the radiation effects and the dose received by individuals, that the current study is concerned

  20. Generalized quantum interference of correlated photon pairs

    Science.gov (United States)

    Kim, Heonoh; Lee, Sang Min; Moon, Han Seb

    2015-01-01

    Superposition and indistinguishablility between probability amplitudes have played an essential role in observing quantum interference effects of correlated photons. The Hong-Ou-Mandel interference and interferences of the path-entangled photon number state are of special interest in the field of quantum information technologies. However, a fully generalized two-photon quantum interferometric scheme accounting for the Hong-Ou-Mandel scheme and path-entangled photon number states has not yet been proposed. Here we report the experimental demonstrations of the generalized two-photon interferometry with both the interferometric properties of the Hong-Ou-Mandel effect and the fully unfolded version of the path-entangled photon number state using photon-pair sources, which are independently generated by spontaneous parametric down-conversion. Our experimental scheme explains two-photon interference fringes revealing single- and two-photon coherence properties in a single interferometer setup. Using the proposed interferometric measurement, it is possible to directly estimate the joint spectral intensity of a photon pair source. PMID:25951143