WorldWideScience

Sample records for effective resistance metric

  1. Attack-Resistant Trust Metrics

    Science.gov (United States)

    Levien, Raph

    The Internet is an amazingly powerful tool for connecting people together, unmatched in human history. Yet, with that power comes great potential for spam and abuse. Trust metrics are an attempt to compute the set of which people are trustworthy and which are likely attackers. This chapter presents two specific trust metrics developed and deployed on the Advogato Website, which is a community blog for free software developers. This real-world experience demonstrates that the trust metrics fulfilled their goals, but that for good results, it is important to match the assumptions of the abstract trust metric computation to the real-world implementation.

  2. Toward an ozone standard to protect vegetation based on effective dose: a review of deposition resistances and a possible metric

    Science.gov (United States)

    Massman, W. J.

    Present air quality standards to protect vegetation from ozone are based on measured concentrations (i.e., exposure) rather than on plant uptake rates (or dose). Some familiar cumulative exposure-based indices include SUM06, AOT40, and W126. However, plant injury is more closely related to dose, or more appropriately to effective dose, than to exposure. This study develops and applies a simple model for estimating effective ozone dose that combines the plant canopy's rate of stomatal ozone uptake with the plant's defense to ozone uptake. Here the plant defense is explicitly parameterized as a function of gross photosynthesis and the model is applied using eddy covariance (ozone and CO 2) flux data obtained at a vineyard site in the San Joaquin Valley during the California Ozone Deposition Experiment (CODE91). With the ultimate intention of applying these concepts using prognostic models and remotely sensed data, the pathways for ozone deposition are parameterized (as much as possible) in terms of canopy LAI and the surface friction velocity. Results indicate that (1) the daily maximum potential for plant injury (based on effective dose) tends to coincide with the daily peak in ozone mixing ratio (ppbV), (2) potentially there are some significant differences between ozone metrics based on dose (no plant defense) and effective dose, and (3) nocturnal conductance can contribute significantly to the potential for plant ozone injury.

  3. Toward an ozone standard to protect vegetation based on effective dose: A review of deposition resistances and a possible metric

    Science.gov (United States)

    W. J. Massman

    2004-01-01

    Present air quality standards to protect vegetation from ozone are based on measured concentrations (i.e., exposure) rather than on plant uptake rates (or dose). Some familiar cumulative exposure-based indices include SUM06, AOT40, and W126. However, plant injury is more closely related to dose, or more appropriately to effective dose, than to exposure. This study...

  4. Cosmology in massive gravity with effective composite metric

    Energy Technology Data Exchange (ETDEWEB)

    Heisenberg, Lavinia [Institute for Theoretical Studies, ETH Zurich Clausiusstrasse 47, 8092 Zurich (Switzerland); Refregier, Alexandre, E-mail: lavinia.heisenberg@eth-its.ethz.ch, E-mail: alexandre.refregier@phys.ethz.ch [Institute for Astronomy, Department of Physics, ETH Zurich, Wolfgang-Pauli-Strasse 27, 8093, Zurich (Switzerland)

    2016-09-01

    This paper is dedicated to scrutinizing the cosmology in massive gravity. A matter field of the dark sector is coupled to an effective composite metric while a standard matter field couples to the dynamical metric in the usual way. For this purpose, we study the dynamical system of cosmological solutions by using phase analysis, which provides an overview of the class of cosmological solutions in this setup. This also permits us to study the critical points of the cosmological equations together with their stability. We show the presence of stable attractor de Sitter critical points relevant to the late-time cosmic acceleration. Furthermore, we study the tensor, vector and scalar perturbations in the presence of standard matter fields and obtain the conditions for the absence of ghost and gradient instabilities. Hence, massive gravity in the presence of the effective composite metric can accommodate interesting dark energy phenomenology, that can be observationally distinguished from the standard model according to the expansion history and cosmic growth.

  5. Metric Power and the Academic Self: Neoliberalism, Knowledge and Resistance in the British University

    Directory of Open Access Journals (Sweden)

    Zeena Feldman

    2018-01-01

    Full Text Available This article discusses the experience of being an academic in the UK in the contemporary climate of neoliberal capitalism and ‘metric power’ (Beers 2016. Drawing on existing literature and our own practice, the first portion of the paper explores the relationship between neoliberalism, metrics and knowledge. We then examine how neoliberal mantras and instruments impact the university’s structures and processes, and reflect on consequences for the academic self. We take as a starting point the context of increasing workloads and the pressure on academics to excel in multiple roles, from ‘world-leading’ researchers to ‘excellent’ teachers and ‘service providers’ to professional administrators performing recruitment and (selfmarketing tasks. Neoliberal academia, we suggest, promotes a meritocratic ideology of individual achievement that frames success and failure as purely personal ‘achievements’, which encourages a competitive ethos and chronic self-criticism. This article insists that these problems need to be understood in the context of neoliberal policy-making and the corporatisation of knowledge, including funding cuts and grant imperatives, the low status of teaching, the cynical instrumentation of university league tables, and increased institutional reliance on precarious academic labour. The article goes on to focus on responses that resist, challenge or, in some cases, compound, the problems identified in part one. Responses by dissatisfied academics range in style and approach – some decide against an academic career; others adopt a strategy of individual withdrawal within the system by trying to create and protect spaces of independence – for example, by refusing to engage beyond officially required minimums. This article argues that opportunities for positive systemic change can be found in collective efforts to oppose the status quo and to create alternatives for how academic labour is organised. Therein

  6. Effects of subsampling of passive acoustic recordings on acoustic metrics.

    Science.gov (United States)

    Thomisch, Karolin; Boebel, Olaf; Zitterbart, Daniel P; Samaran, Flore; Van Parijs, Sofie; Van Opzeeland, Ilse

    2015-07-01

    Passive acoustic monitoring is an important tool in marine mammal studies. However, logistics and finances frequently constrain the number and servicing schedules of acoustic recorders, requiring a trade-off between deployment periods and sampling continuity, i.e., the implementation of a subsampling scheme. Optimizing such schemes to each project's specific research questions is desirable. This study investigates the impact of subsampling on the accuracy of two common metrics, acoustic presence and call rate, for different vocalization patterns (regimes) of baleen whales: (1) variable vocal activity, (2) vocalizations organized in song bouts, and (3) vocal activity with diel patterns. To this end, above metrics are compared for continuous and subsampled data subject to different sampling strategies, covering duty cycles between 50% and 2%. The results show that a reduction of the duty cycle impacts negatively on the accuracy of both acoustic presence and call rate estimates. For a given duty cycle, frequent short listening periods improve accuracy of daily acoustic presence estimates over few long listening periods. Overall, subsampling effects are most pronounced for low and/or temporally clustered vocal activity. These findings illustrate the importance of informed decisions when applying subsampling strategies to passive acoustic recordings or analyses for a given target species.

  7. IDENTIFYING MARKETING EFFECTIVENESS METRICS (Case study: East Azerbaijan`s industrial units)

    OpenAIRE

    Faridyahyaie, Reza; Faryabi, Mohammad; Bodaghi Khajeh Noubar, Hossein

    2012-01-01

    The Paper attempts to identify marketing eff ectiveness metrics in industrial units. The metrics investigated in this study are completely applicable and comprehensive, and consequently they can evaluate marketing eff ectiveness in various industries. The metrics studied include: Market Share, Profitability, Sales Growth, Customer Numbers, Customer Satisfaction and Customer Loyalty. The findings indicate that these six metrics are impressive when measuring marketing effectiveness. Data was ge...

  8. Effects of Metric Change on Workers’ Tools and Training.

    Science.gov (United States)

    1981-07-01

    understanding of the metric system, and particularly a lack of fluency in converting customary measurements to metric measuremerts, may increase the...assembly, installing, and repairing occupations 84 Painting, plastering, waterproofing, cementing , and related occupations 85 Excavating, grading... cementing , and related occupations 85 Excavating, grading, paving, and related occupations 86 Construction occupations, n.e.c. 89 Structural work

  9. Effecting IT infrastructure culture change: management by processes and metrics

    Science.gov (United States)

    Miller, R. L.

    2001-01-01

    This talk describes the processes and metrics used by Jet Propulsion Laboratory to bring about the required IT infrastructure culture change to update and certify, as Y2K compliant, thousands of computers and millions of lines of code.

  10. Use of metrics in an effective ALARA program

    International Nuclear Information System (INIS)

    Bates, B.B. Jr.

    1996-01-01

    ALARA radiological protection programs require metrics to meet their objectives. Sources of metrics include external dosimetry; internal dosimetry; radiological occurrences from the occurrence reporting an processing system (ORPS); and radiological incident reports (RIR). The sources themselves contain an abundance of specific open-quotes indicators.close quotes To choose the site-specific indicators that will be tracked and trended requires careful review. Justification is needed to defend the indicators selected and maybe even stronger justification is needed for those indicators that are available, but not chosen as a metric. Historically, the many different sources of information resided in a plethora of locations. Even the same type of metric had data located in different areas and could not be easily totaled for the entire Site. This required the end user to expend valuable time and effort to locate the data they needed. To address this problem, a central metrics database has been developed so that a customer can have all their questions addressed quickly and correctly. The database was developed in the beginning to answer some of the customer's most frequently asked questions. IL is now also a tool to communicate the status of the radiation protection program to facility managers. Finally, it also addresses requirements contained in the Rad Con manual and the 10CFR835 implementation guides. The database uses currently available, open-quotes user friendly,close quotes software and contains information from RIR's, ORPS, and external dosimetry records specific to ALARA performance indicators. The database is expandable to allow new metrics input. Specific reports have been developed to assist customers in their tracking and trending of ALARA metrics. These include quarterly performance indicator reports, monthly radiological incident reports, monthly external dose history and goals tracking reports, and the future use of performance indexing

  11. Common metrics. Comparing the warming effect of climate forcers in climate policy; Common metrics. Laempenemiseen vaikuttavien paeaestoejen yhteismitallistaminen ilmastopolitiikassa

    Energy Technology Data Exchange (ETDEWEB)

    Lindroos, T. J.; Ekholm, T.; Savolainen, I.

    2012-11-15

    Climate policy needs a relatively simple method to compare the warming effect of different greenhouse gases (GHGs). Otherwise it would be necessary to negotiate a different reduction target for each gas. At the moment, Global Warming Potential (GWP) concept is used to compare different GHGs. Numerical values of GWP factors have been updated alongside with scientific understanding and majority seems content to the GWP. From 2005 onwards there have been many proposals of optional metrics. The most well known is Global Temperature change Potential (GTP) concept which measures the change of temperature as does global climate policies. The decision between metrics is a multicriteria decision which should include at least the coherence with climate policy and cost efficiency. The GWP concept may be a little more difficult to understand than the GTP but it is more cost efficient. Alongside with new metrics, scientists and politicians have started to discuss of new emission which have an effect on warming. These Short Lived Climate Forcers (SLCFs) have either warming or cooling effect. Their effect can be presented with GWP and GTP but the uncertainties in the emission factors are large. In total, SLCFs reduce overall emissions of EU approximately 1% in year 2000. NO{sub x}, SO{sub x} (cooling) and black carbon (warming) emissions were the biggest factors. EU is planning to reduce the SLCF emissions to achieve health and environmental benefits, but at the same time this reduces the effect of EU's climate policies by approximately 10%. Uncertainties in the estimates are large. (orig.)

  12. Effective use of metrics in an ALARA program

    International Nuclear Information System (INIS)

    Bates, B.B. Jr.

    1996-01-01

    ALARA radiological protection programs require metrics to meet their objectives. Sources of metrics include; external dosimetry; internal dosimetry; radiological occurrences from the occurrence reporting and processing system (ORPS); and radiological incident reports (RIR). The sources themselves contain an abundance of specific ''indicators''. To choose the site-specific indicators that will be tracked and trended requires careful review. This required the end users to expend valuable time and effort to locate the data they needed. To address this problem, a central metrics database has been developed so that customers can have all their questions addressed quickly and correctly. The database was developed in the beginning to answer some of the customer's most frequently asked questions. It is now also a tool to communicate the status of the radiation protection program to facility managers. Finally it also addresses requirements contained in the Rad Con manual and the 10CFR835 implementation guides. The database uses currently available, ''user friendly'', software and contains information from RIR's, ORPS, and external dosimetry records specific to ALARA performance indicators. The database is expandable to allow new metrics input. Specific reports have been developed to assist customers in their tracking and trending of ALARA metrics

  13. Robust Design Impact Metrics: Measuring the effect of implementing and using Robust Design

    DEFF Research Database (Denmark)

    Ebro, Martin; Olesen, Jesper; Howard, Thomas J.

    2014-01-01

    Measuring the performance of an organisation’s product development process can be challenging due to the limited use of metrics in R&D. An organisation considering whether to use Robust Design as an integrated part of their development process may find it difficult to define whether it is relevant......, and afterwards measure the effect of having implemented it. This publication identifies and evaluates Robust Design-related metrics and finds that 2 metrics are especially useful: 1) Relative amount of R&D Resources spent after Design Verification and 2) Number of ‘change notes’ after Design Verification....... The metrics have been applied in a case company to test the assumptions made during the evaluation. It is concluded that the metrics are useful and relevant, but further work is necessary to make a proper overview and categorisation of different types of robustness related metrics....

  14. Using community-level metrics to monitor the effects of marine protected areas on biodiversity.

    Science.gov (United States)

    Soykan, Candan U; Lewison, Rebecca L

    2015-06-01

    Marine protected areas (MPAs) are used to protect species, communities, and their associated habitats, among other goals. Measuring MPA efficacy can be challenging, however, particularly when considering responses at the community level. We gathered 36 abundance and 14 biomass data sets on fish assemblages and used meta-analysis to evaluate the ability of 22 distinct community diversity metrics to detect differences in community structure between MPAs and nearby control sites. We also considered the effects of 6 covariates-MPA size and age, MPA size and age interaction, latitude, total species richness, and level of protection-on each metric. Some common metrics, such as species richness and Shannon diversity, did not differ consistently between MPA and control sites, whereas other metrics, such as total abundance and biomass, were consistently different across studies. Metric responses derived from the biomass data sets were more consistent than those based on the abundance data sets, suggesting that community-level biomass differs more predictably than abundance between MPA and control sites. Covariate analyses indicated that level of protection, latitude, MPA size, and the interaction between MPA size and age affect metric performance. These results highlight a handful of metrics, several of which are little known, that could be used to meet the increasing demand for community-level indicators of MPA effectiveness. © 2015 Society for Conservation Biology.

  15. [Applicability of traditional landscape metrics in evaluating urban heat island effect].

    Science.gov (United States)

    Chen, Ai-Lian; Sun, Ran-Hao; Chen, Li-Ding

    2012-08-01

    By using 24 landscape metrics, this paper evaluated the urban heat island effect in parts of Beijing downtown area. QuickBird (QB) images were used to extract the landscape type information, and the thermal bands from Landsat Enhanced Thematic Mapper Plus (ETM+) images were used to extract the land surface temperature (LST) in four seasons of the same year. The 24 landscape pattern metrics were calculated at landscape and class levels in a fixed window with 120 mx 120 m in size, with the applicability of these traditional landscape metrics in evaluating the urban heat island effect examined. Among the 24 landscape metrics, only the percentage composition of landscape (PLAND), patch density (PD), largest patch index (LPI), coefficient of Euclidean nearest-neighbor distance variance (ENN_CV), and landscape division index (DIVISION) at landscape level were significantly correlated with the LST in March, May, and November, and the PLAND, LPI, DIVISION, percentage of like adjacencies, and interspersion and juxtaposition index at class level showed significant correlations with the LST in March, May, July, and December, especially in July. Some metrics such as PD, edge density, clumpiness index, patch cohesion index, effective mesh size, splitting index, aggregation index, and normalized landscape shape index showed varying correlations with the LST at different class levels. The traditional landscape metrics could not be appropriate in evaluating the effects of river on LST, while some of the metrics could be useful in characterizing urban LST and analyzing the urban heat island effect, but screening and examining should be made on the metrics.

  16. Effects of Metric Change on Safety in the Workplace for Selected Occupations.

    Science.gov (United States)

    1982-04-21

    to undertake certain types of research regarding the effects of metric con - version. Under the leadership of its research couiittee, the U.S. Metric...Service. At this time there was a growing concern about conditions in the nation’s workplaces -- from Colorado mines to New York City sweatshops ...incidence of worker injury within each occupation was also con - sidered in order to eliminate those occupations that, although they are hazardous

  17. Effect of thematic map misclassification on landscape multi-metric assessment.

    Science.gov (United States)

    Kleindl, William J; Powell, Scott L; Hauer, F Richard

    2015-06-01

    Advancements in remote sensing and computational tools have increased our awareness of large-scale environmental problems, thereby creating a need for monitoring, assessment, and management at these scales. Over the last decade, several watershed and regional multi-metric indices have been developed to assist decision-makers with planning actions of these scales. However, these tools use remote-sensing products that are subject to land-cover misclassification, and these errors are rarely incorporated in the assessment results. Here, we examined the sensitivity of a landscape-scale multi-metric index (MMI) to error from thematic land-cover misclassification and the implications of this uncertainty for resource management decisions. Through a case study, we used a simplified floodplain MMI assessment tool, whose metrics were derived from Landsat thematic maps, to initially provide results that were naive to thematic misclassification error. Using a Monte Carlo simulation model, we then incorporated map misclassification error into our MMI, resulting in four important conclusions: (1) each metric had a different sensitivity to error; (2) within each metric, the bias between the error-naive metric scores and simulated scores that incorporate potential error varied in magnitude and direction depending on the underlying land cover at each assessment site; (3) collectively, when the metrics were combined into a multi-metric index, the effects were attenuated; and (4) the index bias indicated that our naive assessment model may overestimate floodplain condition of sites with limited human impacts and, to a lesser extent, either over- or underestimated floodplain condition of sites with mixed land use.

  18. A comparison of metrics to evaluate the effects of hydro-facility passage stressors on fish

    Energy Technology Data Exchange (ETDEWEB)

    Colotelo, Alison H.; Goldman, Amy E.; Wagner, Katie A.; Brown, Richard S.; Deng, Z. Daniel; Richmond, Marshall C.

    2017-03-01

    Hydropower is the most common form of renewable energy, and countries worldwide are considering expanding hydropower to new areas. One of the challenges of hydropower deployment is mitigation of the environmental impacts including water quality, habitat alterations, and ecosystem connectivity. For fish species that inhabit river systems with hydropower facilities, passage through the facility to access spawning and rearing habitats can be particularly challenging. Fish moving downstream through a hydro-facility can be exposed to a number of stressors (e.g., rapid decompression, shear forces, blade strike and collision, and turbulence), which can all affect fish survival in direct and indirect ways. Many studies have investigated the effects of hydro-turbine passage on fish; however, the comparability among studies is limited by variation in the metrics and biological endpoints used. Future studies investigating the effects of hydro-turbine passage should focus on using metrics and endpoints that are easily comparable. This review summarizes four categories of metrics that are used in fisheries research and have application to hydro-turbine passage (i.e., mortality, injury, molecular metrics, behavior) and evaluates them based on several criteria (i.e., resources needed, invasiveness, comparability among stressors and species, and diagnostic properties). Additionally, these comparisons are put into context of study setting (i.e., laboratory vs. field). Overall, injury and molecular metrics are ideal for studies in which there is a need to understand the mechanisms of effect, whereas behavior and mortality metrics provide information on the whole body response of the fish. The study setting strongly influences the comparability among studies. In laboratory-based studies, stressors can be controlled by both type and magnitude, allowing for easy comparisons among studies. In contrast, field studies expose fish to realistic passage environments but the comparability is

  19. A metric for characterizing the effectiveness of thermal mass in building materials

    International Nuclear Information System (INIS)

    Talyor, Robert A.; Miner, Mark

    2014-01-01

    Highlights: • Proposes a metric for interior thermal mass materials (floors, walls, counters). • Simple, yet effective, metric composed of easily calculated ‘local’ and ‘global’ variables. • Like Energy Star, the proposed metric gives a single number to aid consumer choice. • The metric is calculated and compared for selected, readily available data. • Drywall, concrete flooring, and wood paneling are quite effective thermal mass. - Abstract: Building energy use represents approximately 25% of the average total global energy consumption (for both residential and commercial buildings). Heating, ventilation, and air conditioning (HVAC) – in most climates – embodies the single largest draw inside our buildings. In many countries around the world a concerted effort is being made towards retrofitting existing buildings to improve energy efficiency. Better windows, insulation, and ducting can make drastic differences in the energy consumption of a building HVAC system. Even with these improvements, HVAC systems are still required to compensate for daily and seasonal temperature swings of the surrounding environment. Thermal mass inside the thermal envelope can help to alleviate these swings. While it is possible to add specialty thermal mass products to buildings for this purpose, commercial uptake of these products is low. Common building interior building materials (e.g. flooring, walls, countertops) are often overlooked as thermal mass products, but herein we propose and analyze non-dimensional metrics for the ‘benefit’ of selected commonly available products. It was found that location-specific variables (climate, electricity price, material price, insolation) can have more than an order of magnitude influence in the calculated metrics for the same building material. Overall, this paper provides guidance on the most significant contributors to indoor thermal mass, and presents a builder- and consumer-friendly metric to inform decisions about

  20. Developing Metrics for Effective Teaching in Agricultural Education

    Science.gov (United States)

    Lawver, Rebecca G.; McKim, Billy R.; Smith, Amy R.; Aschenbrener, Mollie S.; Enns, Kellie

    2016-01-01

    Research on effective teaching has been conducted in a variety of settings for more than 40 years. This study offers direction for future effective teaching research in secondary agricultural education and has implications for career and technical education. Specifically, 142 items consisting of characteristics, behaviors, and/or techniques…

  1. Resistive effects in EXTRAP

    International Nuclear Information System (INIS)

    Tendler, M.

    1987-01-01

    Theoretical studies of the resistive equilibrium and stability of an EXTRAP Z-pinch are reported. Extending the previous analysis we reasses properties of the resistive equilibrium in EXTRAP with the emphasis on the time dependence of the latter. We also qualitatively consider the role of resistive instabilities in EXTRAP, showing that the typical timescale of the filamentation of the discharge (i.e., the non-linear development of the tearing instability) is comparable, at present, to the discharge duration. On the other hand, we emphasize that this phenomenon may still be consistent with the experimental observation of the Bennet's equilibrium. The processes of the current start-up and ramp-up are also analysed for EXTRAP and it is shown that the peculiarities of these processes may lead to the compression oscillations around an evolving rather stable equilibrium. Finally, some consequences of the average minimum-B concept for EXTRAP are discussed and it is shown that this issue virtually reduces to the appearance of the negative curvature of the magnetic field at the periphery. The maximum attainable value of β at the periphery of the pinch is obtained, as required by the ballooning stability criterion. The influence of the finite resistivity on the ballooning mode is also estimated. (orig.)

  2. Resistive effects in EXTRAP

    International Nuclear Information System (INIS)

    Tendler, M.

    1985-10-01

    Theoretical studies of the resistive equilibrium and stability of an EXTRAP z-pinch are reported. Extending the previous analysis we reassess properties of the resistive equilibrium in EXTRAP with the emphasis on the time dependence of the latter. We also qualitatively consider the role of resistive instabilities in EXTRAP, showing that the typical timescale of the filamentation of the discharge (i.e. the non-linear development of the tearing instability) is comparable at present, to the discharge duration. On the other hand, we emphasize that this phenomenon may still be consistent with the experimental observation of the Bennet's equilibrium. The processes of the current start-up and ramp up are also analysed for EXTRAP and it is shown that the peculiarities if these processes in EXTRAP may lead to the compression oscillations around and evolving rather stable equilibrium. The frequency of these oscillations is given. Finally, some consequences of the average minimum-B concept for EXTRAP are discussed and it is shown that this issue virtually reduces to the appearance of the negative curvature of the magnetic field at the periphery. The maximum attainable value of β at the periphery of the pinch is obtained, as required by the ballooning stability criterion. The influence of the finite resistivity on the ballooning mode is also estimated. With 4 figures and 21 refs. (Author)

  3. Linking customer and financial metrics to shareholder value : The leverage effect in customer-based valuation

    NARCIS (Netherlands)

    Schulze, C.; Skiera, B.; Wiesel, T.

    Customers are the most important assets of most companies, such that customer equity has been used as a proxy for shareholder value. However, linking customer metrics to shareholder value without considering debt and non-operating assets ignores their effects on relative changes in customer equity

  4. Effectively identifying user profiles in network and host metrics

    Science.gov (United States)

    Murphy, John P.; Berk, Vincent H.; Gregorio-de Souza, Ian

    2010-04-01

    This work presents a collection of methods that is used to effectively identify users of computers systems based on their particular usage of the software and the network. Not only are we able to identify individual computer users by their behavioral patterns, we are also able to detect significant deviations in their typical computer usage over time, or compared to a group of their peers. For instance, most people have a small, and relatively unique selection of regularly visited websites, certain email services, daily work hours, and typical preferred applications for mandated tasks. We argue that these habitual patterns are sufficiently specific to identify fully anonymized network users. We demonstrate that with only a modest data collection capability, profiles of individual computer users can be constructed so as to uniquely identify a profiled user from among their peers. As time progresses and habits or circumstances change, the methods presented update each profile so that changes in user behavior can be reliably detected over both abrupt and gradual time frames, without losing the ability to identify the profiled user. The primary benefit of our methodology allows one to efficiently detect deviant behaviors, such as subverted user accounts, or organizational policy violations. Thanks to the relative robustness, these techniques can be used in scenarios with very diverse data collection capabilities, and data privacy requirements. In addition to behavioral change detection, the generated profiles can also be compared against pre-defined examples of known adversarial patterns.

  5. Metrics to describe the effects of landscape pattern on hydrology in a lotic peatland

    Science.gov (United States)

    Yuan, J.; Cohen, M. J.; Kaplan, D. A.; Acharya, S.; Larsen, L.; Nungesser, M.

    2013-12-01

    Strong reciprocal interactions exist between landscape patterns and ecological processes. Hydrology is the dominant abiotic driver of ecological processes in wetlands, particularly flowing wetlands, but is both the control on and controlled by the geometry of vegetation patterning. Landscape metrics are widely used to quantitatively link pattern and process. Our goal here was to use several candidate spatial pattern metrics to predict the effects of wetland vegetation pattern on hydrologic regime, specifically hydroperiod, in the ridge-slough patterned landscape of the Everglades. The metrics focus on the capacity for longitudinally connected flow, and thus the ability of this low-gradient patterned landscape to route water from upstream. We first explored flow friction cost (FFC), a weighted spatial distance procedure wherein ridges have a high flow cost than sloughs by virtue of their elevation and vegetation structure, to evaluate water movement through different landscape configurations. We also investigated existing published flow metrics, specifically the Directional Connectivity Index (DCI) and Landscape Discharge Competence (LDC), that seek to quantify connectivity, one of the sentinel targets of ecological restoration. Hydroperiod was estimated using a numerical hydrologic model (SWIFT 2D) in real and synthetic landscapes with varying vegetation properties ( patch anisotropy, ridge density). Synthetic landscapes were constrained by the geostatistical properties of the best conserved patterned, and contained five anisotropy levels and seven ridge density levels. These were used to construct the relationship between landscape metrics and hydroperiod. Then, using historical images from 1940 to 2004, we applied the metrics toback-cast hydroperiod. Current vegetation maps were used to test scale dependency for each metric. Our results suggest that both FFC and DCI are good predictors of hydroperiod under free flowing conditions, and that they can be used

  6. A multiple decision support metrics method for effective risk-informed asset management

    International Nuclear Information System (INIS)

    Liming, J.K.; Salter, J.E.

    2004-01-01

    The objective of this paper is to provide electric utilities with a concept for developing and applying effective decision support metrics via integrated risk-informed asset management (RIAM) programs for power stations and generating companies. RIAM is a process by which analysts review historical performance and develop predictive logic models and data analyses to predict critical decision support figures-of-merit (or metrics) for generating station managers and electric utility company executives. These metrics include, but are not limited to, the following: profitability, net benefit, benefit-to-cost ratio, projected return on investment, projected revenue, projected costs, asset value, safety (catastrophic facility damage frequency and consequences, etc.), power production availability (capacity factor, etc.), efficiency (heat rate), and others. RIAM applies probabilistic safety assessment (PSA) techniques and generates predictions in a probabilistic way so that metrics information can be supplied to managers in terms of probability distributions as well as point estimates. This enables the managers to apply the concept of 'confidence levels' in their critical decision-making processes. (authors)

  7. The Use of Performance Metrics for the Assessment of Safeguards Effectiveness at the State Level

    Energy Technology Data Exchange (ETDEWEB)

    Bachner K. M.; George Anzelon, Lawrence Livermore National Laboratory, Livermore, CA Yana Feldman, Lawrence Livermore National Laboratory, Livermore, CA Mark Goodman,Department of State, Washington, DC Dunbar Lockwood, National Nuclear Security Administration, Washington, DC Jonathan B. Sanborn, JBS Consulting, LLC, Arlington, VA.

    2016-07-24

    In the ongoing evolution of International Atomic Energy Agency (IAEA) safeguards at the state level, many safeguards implementation principles have been emphasized: effectiveness, efficiency, non-discrimination, transparency, focus on sensitive materials, centrality of material accountancy for detecting diversion, independence, objectivity, and grounding in technical considerations, among others. These principles are subject to differing interpretations and prioritizations and sometimes conflict. This paper is an attempt to develop metrics and address some of the potential tradeoffs inherent in choices about how various safeguards policy principles are implemented. The paper carefully defines effective safeguards, including in the context of safeguards approaches that take account of the range of state-specific factors described by the IAEA Secretariat and taken note of by the Board in September 2014, and (2) makes use of performance metrics to help document, and to make transparent, how safeguards implementation would meet such effectiveness requirements.

  8. Learning a Novel Detection Metric for the Detection of O’Connell Effect Eclipsing Binaries

    Science.gov (United States)

    Johnston, Kyle; Haber, Rana; Knote, Matthew; Caballero-Nieves, Saida Maria; Peter, Adrian; Petit, Véronique

    2018-01-01

    With the advent of digital astronomy, new benefits and new challenges have been presented to the modern day astronomer. No longer can the astronomer rely on manual processing, instead the profession as a whole has begun to adopt more advanced computational means. Here we focus on the construction and application of a novel time-domain signature extraction methodology and the development of a supporting supervised pattern detection algorithm for the targeted identification of eclipsing binaries which demonstrate a feature known as the O’Connell Effect. A methodology for the reduction of stellar variable observations (time-domain data) into Distribution Fields (DF) is presented. Push-Pull metric learning, a variant of LMNN learning, is used to generate a learned distance metric for the specific detection problem proposed. The metric will be trained on a set of a labelled Kepler eclipsing binary data, in particular systems showing the O’Connell effect. Performance estimates will be presented, as well the results of the detector applied to an unlabeled Kepler EB data set; this work is a crucial step in the upcoming era of big data from the next generation of big telescopes, such as LSST.

  9. Overall Environmental Equipment Effectiveness as a Metric of a Lean and Green Manufacturing System

    Directory of Open Access Journals (Sweden)

    Rosario Domingo

    2015-07-01

    Full Text Available This paper presents a new metric for describing the sustainability improvements achieved, relative to the company’s initial situation, after implementing a lean and green manufacturing system. The final value of this metric is identified as the Overall Environmental Equipment Effectiveness (OEEE, which is used to analyze the evolution between two identified states of the Overall Equipment Effectiveness (OEE and the sustainability together, and references, globally and individually, the production steps. The OEE is a known measure of equipment utilization, which includes the availability, quality and performance of each production step, In addition to these factors, the OEEE incorporates the concept of sustainability based on the calculated environmental impact of the complete product life cycle. Action research based on the different manufacturing processes of a tube fabrication company is conducted to assess the potential impact of this new indicator. The case study demonstrates the compatibility between green and lean manufacturing, using a common metric. The OEEE allows sustainability to be integrated into business decisions, and compares the environmental impact of two states, by identifying the improvements undertaken within the company’s processes.

  10. The effect of assessment scale and metric selection on the greenhouse gas benefits of woody biomass

    International Nuclear Information System (INIS)

    Galik, Christopher S.; Abt, Robert C.

    2012-01-01

    Recent attention has focused on the net greenhouse gas (GHG) implications of using woody biomass to produce energy. In particular, a great deal of controversy has erupted over the appropriate manner and scale at which to evaluate these GHG effects. Here, we conduct a comparative assessment of six different assessment scales and four different metric calculation techniques against the backdrop of a common biomass demand scenario. We evaluate the net GHG balance of woody biomass co-firing in existing coal-fired facilities in the state of Virginia, finding that assessment scale and metric calculation technique do in fact strongly influence the net GHG balance yielded by this common scenario. Those assessment scales that do not include possible market effects attributable to increased biomass demand, including changes in forest area, forest management intensity, and traditional industry production, generally produce less-favorable GHG balances than those that do. Given the potential difficulty small operators may have generating or accessing information on the extent of these market effects, however, it is likely that stakeholders and policy makers will need to balance accuracy and comprehensiveness with reporting and administrative simplicity. -- Highlights: ► Greenhouse gas (GHG) effects of co-firing forest biomass with coal are assessed. ► GHG effect of replacing coal with forest biomass linked to scale, analytic approach. ► Not accounting for indirect market effects yields poorer relative GHG balances. ► Accounting systems must balance comprehensiveness with administrative simplicity.

  11. A unifying framework for metrics for aggregating the climate effect of different emissions

    International Nuclear Information System (INIS)

    Tol, Richard S J; Berntsen, Terje K; Fuglestvedt, Jan S; O’Neill, Brian C; Shine, Keith P

    2012-01-01

    Multi-gas approaches to climate change policies require a metric establishing ‘equivalences’ among emissions of various species. Climate scientists and economists have proposed four kinds of such metrics and debated their relative merits. We present a unifying framework that clarifies the relationships among them. We show, as have previous authors, that the global warming potential (GWP), used in international law to compare emissions of greenhouse gases, is a special case of the global damage potential (GDP), assuming (1) a finite time horizon, (2) a zero discount rate, (3) constant atmospheric concentrations, and (4) impacts that are proportional to radiative forcing. Both the GWP and GDP follow naturally from a cost–benefit framing of the climate change issue. We show that the global temperature change potential (GTP) is a special case of the global cost potential (GCP), assuming a (slight) fall in the global temperature after the target is reached. We show how the four metrics should be generalized if there are intertemporal spillovers in abatement costs, distinguishing between private (e.g., capital stock turnover) and public (e.g., induced technological change) spillovers. Both the GTP and GCP follow naturally from a cost-effectiveness framing of the climate change issue. We also argue that if (1) damages are zero below a threshold and (2) infinitely large above a threshold, then cost-effectiveness analysis and cost–benefit analysis lead to identical results. Therefore, the GCP is a special case of the GDP. The UN Framework Convention on Climate Change uses the GWP, a simplified cost–benefit concept. The UNFCCC is framed around the ultimate goal of stabilizing greenhouse gas concentrations. Once a stabilization target has been agreed under the convention, implementation is clearly a cost-effectiveness problem. It would therefore be more consistent to use the GCP or its simplification, the GTP. (letter)

  12. Effective dose efficiency: an application-specific metric of quality and dose for digital radiography

    Energy Technology Data Exchange (ETDEWEB)

    Samei, Ehsan; Ranger, Nicole T; Dobbins, James T III; Ravin, Carl E, E-mail: samei@duke.edu [Carl E Ravin Advanced Imaging Laboratories, Department of Radiology (United States)

    2011-08-21

    The detective quantum efficiency (DQE) and the effective DQE (eDQE) are relevant metrics of image quality for digital radiography detectors and systems, respectively. The current study further extends the eDQE methodology to technique optimization using a new metric of the effective dose efficiency (eDE), reflecting both the image quality as well as the effective dose (ED) attributes of the imaging system. Using phantoms representing pediatric, adult and large adult body habitus, image quality measurements were made at 80, 100, 120 and 140 kVp using the standard eDQE protocol and exposures. ED was computed using Monte Carlo methods. The eDE was then computed as a ratio of image quality to ED for each of the phantom/spectral conditions. The eDQE and eDE results showed the same trends across tube potential with 80 kVp yielding the highest values and 120 kVp yielding the lowest. The eDE results for the pediatric phantom were markedly lower than the results for the adult phantom at spatial frequencies lower than 1.2-1.7 mm{sup -1}, primarily due to a correspondingly higher value of ED per entrance exposure. The relative performance for the adult and large adult phantoms was generally comparable but affected by kVps. The eDE results for the large adult configuration were lower than the eDE results for the adult phantom, across all spatial frequencies (120 and 140 kVp) and at spatial frequencies greater than 1.0 mm{sup -1} (80 and 100 kVp). Demonstrated for chest radiography, the eDE shows promise as an application-specific metric of imaging performance, reflective of body habitus and radiographic technique, with utility for radiography protocol assessment and optimization.

  13. arXiv Hybrid Fluid Models from Mutual Effective Metric Couplings

    CERN Document Server

    Kurkela, Aleksi; Preis, Florian; Rebhan, Anton; Soloviev, Alexander

    Motivated by a semi-holographic approach to the dynamics of quark-gluon plasma which combines holographic and perturbative descriptions of a strongly coupled infrared and a more weakly coupled ultraviolet sector, we construct a hybrid two-fluid model where interactions between its two sectors are encoded by their effective metric backgrounds, which are determined mutually by their energy-momentum tensors. We derive the most general consistent ultralocal interactions such that the full system has a total conserved energy-momentum tensor in flat Minkowski space and study its consequences in and near thermal equilibrium by working out its phase structure and its hydrodynamic modes.

  14. Brief educational interventions to improve performance on novel quality metrics in ambulatory settings in Kenya: A multi-site pre-post effectiveness trial.

    Science.gov (United States)

    Korom, Robert Ryan; Onguka, Stephanie; Halestrap, Peter; McAlhaney, Maureen; Adam, Mary

    2017-01-01

    The quality of primary care delivered in resource-limited settings is low. While some progress has been made using educational interventions, it is not yet clear how to sustainably improve care for common acute illnesses in the outpatient setting. Management of urinary tract infection is particularly important in resource-limited settings, where it is commonly diagnosed and associated with high levels of antimicrobial resistance. We describe an educational programme targeting non-physician health care providers and its effects on various clinical quality metrics for urinary tract infection. We used a series of educational interventions including 1) formal introduction of a clinical practice guideline, 2) peer-to-peer chart review, and 3) peer-reviewed literature describing local antimicrobial resistance patterns. Interventions were conducted for clinical officers (N = 24) at two outpatient centers near Nairobi, Kenya over a one-year period. The medical records of 474 patients with urinary tract infections were scored on five clinical quality metrics, with the primary outcome being the proportion of cases in which the guideline-recommended antibiotic was prescribed. The results at baseline and following each intervention were compared using chi-squared tests and unpaired two-tailed T-tests for significance. Logistic regression analysis was used to assess for possible confounders. Clinician adherence to the guideline-recommended antibiotic improved significantly during the study period, from 19% at baseline to 68% following all interventions (Χ2 = 150.7, p quality score also improved significantly from an average of 2.16 to 3.00 on a five-point scale (t = 6.58, p educational interventions can dramatically improve the quality of care for routine acute illnesses in the outpatient setting. Measurement of quality metrics allows for further targeting of educational interventions depending on the needs of the providers and the community. Further study is needed to expand

  15. Semantic metrics

    OpenAIRE

    Hu, Bo; Kalfoglou, Yannis; Dupplaw, David; Alani, Harith; Lewis, Paul; Shadbolt, Nigel

    2006-01-01

    In the context of the Semantic Web, many ontology-related operations, e.g. ontology ranking, segmentation, alignment, articulation, reuse, evaluation, can be boiled down to one fundamental operation: computing the similarity and/or dissimilarity among ontological entities, and in some cases among ontologies themselves. In this paper, we review standard metrics for computing distance measures and we propose a series of semantic metrics. We give a formal account of semantic metrics drawn from a...

  16. Assessing the Effects of Data Compression in Simulations Using Physically Motivated Metrics

    Directory of Open Access Journals (Sweden)

    Daniel Laney

    2014-01-01

    Full Text Available This paper examines whether lossy compression can be used effectively in physics simulations as a possible strategy to combat the expected data-movement bottleneck in future high performance computing architectures. We show that, for the codes and simulations we tested, compression levels of 3–5X can be applied without causing significant changes to important physical quantities. Rather than applying signal processing error metrics, we utilize physics-based metrics appropriate for each code to assess the impact of compression. We evaluate three different simulation codes: a Lagrangian shock-hydrodynamics code, an Eulerian higher-order hydrodynamics turbulence modeling code, and an Eulerian coupled laser-plasma interaction code. We compress relevant quantities after each time-step to approximate the effects of tightly coupled compression and study the compression rates to estimate memory and disk-bandwidth reduction. We find that the error characteristics of compression algorithms must be carefully considered in the context of the underlying physics being modeled.

  17. Effects of noise and confidence thresholds in nominal and metric Axelrod dynamics of social influence

    Science.gov (United States)

    de Sanctis, Luca; Galla, Tobias

    2009-04-01

    We study the effects of bounded confidence thresholds and of interaction and external noise on Axelrod’s model of social influence. Our study is based on a combination of numerical simulations and an integration of the mean-field master equation describing the system in the thermodynamic limit. We find that interaction thresholds affect the system only quantitatively, but that they do not alter the basic phase structure. The known crossover between an ordered and a disordered state in finite systems subject to external noise persists in models with general confidence threshold. Interaction noise here facilitates the dynamics and reduces relaxation times. We also study Axelrod systems with metric features and point out similarities and differences compared to models with nominal features.

  18. Metrics for aggregating the climate effects of different emissions: a unifying framework

    NARCIS (Netherlands)

    Tol, R.S.J.; Berntsen, T.K.; O'Neill, B.C.; Fuglestvedt, J.S.; Shine, K.P.

    2012-01-01

    Multi-gas approaches to climate change policies require a metric establishing equivalences among emissions of various species. Climate scientists and economists have proposed four kinds of such metrics and debated their relative merits. We present a unifying framework that clarifies the

  19. Comparing Single Case Design Overlap-Based Effect Size Metrics from Studies Examining Speech Generating Device Interventions

    Science.gov (United States)

    Chen, Mo; Hyppa-Martin, Jolene K.; Reichle, Joe E.; Symons, Frank J.

    2016-01-01

    Meaningfully synthesizing single case experimental data from intervention studies comprised of individuals with low incidence conditions and generating effect size estimates remains challenging. Seven effect size metrics were compared for single case design (SCD) data focused on teaching speech generating device use to individuals with…

  20. The Effect of Electronic Word of Mouth on Sales: A Meta-Analytic Review of Platform, Product, and Metric Factors

    NARCIS (Netherlands)

    Babic, A.; Sotgiu, Francesca; de Valck, K.; Bijmolt, T.H.A.

    2016-01-01

    The increasing amount of electronic word of mouth (eWOM) has significantly affected the way consumers make purchase decisions. Empirical studies have established an effect of eWOM on sales but disagree on which online platforms, products, and eWOM metrics moderate this effect. The authors conduct a

  1. G-index: A new metric to describe dynamic refractive index effects in HPLC absorbance detection.

    Science.gov (United States)

    Kraiczek, Karsten G; Rozing, Gerard P; Zengerle, Roland

    2018-09-01

    High performance liquid chromatography (HPLC) with a solvent gradient and absorbance detection is one of the most widely used methods in analytical chemistry. The observed absorbance baseline is affected by the changes in the refractive index (RI) of the mobile phase. Near the limited of detection, this complicates peak quantitation. The general aspects of these RI-induced apparent absorbance effects are discussed. Two different detectors with fundamentally different optics and flow cell concepts, a variable-wavelength detector equipped with a conventional flow cell and a diode-array detector equipped with a liquid core waveguide flow cell, are compared with respect to their RI behavior. A simple method to separate static - partly unavoidable - RI effects from dynamic RI effects is presented. It is shown that the dynamic RI behavior of an absorbance detector can be well described using a single, relatively easy-to-determine metric called the G-index. The G-index is typically in the order of a few seconds and its sign depends on the optical flow cell concept. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Metric learning

    CERN Document Server

    Bellet, Aurelien; Sebban, Marc

    2015-01-01

    Similarity between objects plays an important role in both human cognitive processes and artificial systems for recognition and categorization. How to appropriately measure such similarities for a given task is crucial to the performance of many machine learning, pattern recognition and data mining methods. This book is devoted to metric learning, a set of techniques to automatically learn similarity and distance functions from data that has attracted a lot of interest in machine learning and related fields in the past ten years. In this book, we provide a thorough review of the metric learnin

  3. Brachytherapy Partial Breast Irradiation: Analyzing Effect of Source Configurations on Dose Metrics Relevant to Toxicity

    International Nuclear Information System (INIS)

    Cormack, Robert A.; Devlin, Phillip M.

    2008-01-01

    Purpose: Recently, the use of partial breast irradiation (PBI) for patients with early-stage breast cancer with low-risk factors has increased. The volume of the high-dose regions has been correlated with toxicity in interstitial treatment. Although no such associations have been made in applicator-based experience, new applicators are being developed that use complex noncentered source configurations. This work studied the effect of noncentered source placements on the volume of the high-dose regions around a spherical applicator. Methods and Materials: Many applicator configurations were numerically simulated for a range of inflation radii. For each configuration, a dose homogeneity index was used as a dose metric to measure the volume of the high-dose region. Results: All multisource configurations examined resulted in an increase of the high-dose region compared with a single-center source. The resulting decrease in the prescription dose homogeneity index was more pronounced for sources further from the center of the applicator, and the effect was reduced as the number of dwell locations was increased. Conclusion: The geometries of particular applicators were not considered to achieve a more general result. On the basis of the calculations of this work, it would appear that treatment using noncentered dwell locations will lead to an increase in the volume of the high-dose regions

  4. Effects of metric hierarchy and rhyme predictability on word duration in The Cat in the Hat.

    Science.gov (United States)

    Breen, Mara

    2018-05-01

    Word durations convey many types of linguistic information, including intrinsic lexical features like length and frequency and contextual features like syntactic and semantic structure. The current study was designed to investigate whether hierarchical metric structure and rhyme predictability account for durational variation over and above other features in productions of a rhyming, metrically-regular children's book: The Cat in the Hat (Dr. Seuss, 1957). One-syllable word durations and inter-onset intervals were modeled as functions of segment number, lexical frequency, word class, syntactic structure, repetition, and font emphasis. Consistent with prior work, factors predicting longer word durations and inter-onset intervals included more phonemes, lower frequency, first mention, alignment with a syntactic boundary, and capitalization. A model parameter corresponding to metric grid height improved model fit of word durations and inter-onset intervals. Specifically, speakers realized five levels of metric hierarchy with inter-onset intervals such that interval duration increased linearly with increased height in the metric hierarchy. Conversely, speakers realized only three levels of metric hierarchy with word duration, demonstrating that they shortened the highly predictable rhyme resolutions. These results further understanding of the factors that affect spoken word duration, and demonstrate the myriad cues that children receive about linguistic structure from nursery rhymes. Copyright © 2018 Elsevier B.V. All rights reserved.

  5. Brief educational interventions to improve performance on novel quality metrics in ambulatory settings in Kenya: A multi-site pre-post effectiveness trial

    Science.gov (United States)

    Onguka, Stephanie; Halestrap, Peter; McAlhaney, Maureen; Adam, Mary

    2017-01-01

    Background The quality of primary care delivered in resource-limited settings is low. While some progress has been made using educational interventions, it is not yet clear how to sustainably improve care for common acute illnesses in the outpatient setting. Management of urinary tract infection is particularly important in resource-limited settings, where it is commonly diagnosed and associated with high levels of antimicrobial resistance. We describe an educational programme targeting non-physician health care providers and its effects on various clinical quality metrics for urinary tract infection. Methods We used a series of educational interventions including 1) formal introduction of a clinical practice guideline, 2) peer-to-peer chart review, and 3) peer-reviewed literature describing local antimicrobial resistance patterns. Interventions were conducted for clinical officers (N = 24) at two outpatient centers near Nairobi, Kenya over a one-year period. The medical records of 474 patients with urinary tract infections were scored on five clinical quality metrics, with the primary outcome being the proportion of cases in which the guideline-recommended antibiotic was prescribed. The results at baseline and following each intervention were compared using chi-squared tests and unpaired two-tailed T-tests for significance. Logistic regression analysis was used to assess for possible confounders. Findings Clinician adherence to the guideline-recommended antibiotic improved significantly during the study period, from 19% at baseline to 68% following all interventions (Χ2 = 150.7, p < 0.001). The secondary outcome of composite quality score also improved significantly from an average of 2.16 to 3.00 on a five-point scale (t = 6.58, p < 0.001). Interventions had different effects at different clinical sites; the primary outcome of appropriate antibiotic prescription was met 83% of the time at Penda Health, and 50% of the time at AICKH, possibly reflecting

  6. Cyber threat metrics.

    Energy Technology Data Exchange (ETDEWEB)

    Frye, Jason Neal; Veitch, Cynthia K.; Mateski, Mark Elliot; Michalski, John T.; Harris, James Mark; Trevino, Cassandra M.; Maruoka, Scott

    2012-03-01

    Threats are generally much easier to list than to describe, and much easier to describe than to measure. As a result, many organizations list threats. Fewer describe them in useful terms, and still fewer measure them in meaningful ways. This is particularly true in the dynamic and nebulous domain of cyber threats - a domain that tends to resist easy measurement and, in some cases, appears to defy any measurement. We believe the problem is tractable. In this report we describe threat metrics and models for characterizing threats consistently and unambiguously. The purpose of this report is to support the Operational Threat Assessment (OTA) phase of risk and vulnerability assessment. To this end, we focus on the task of characterizing cyber threats using consistent threat metrics and models. In particular, we address threat metrics and models for describing malicious cyber threats to US FCEB agencies and systems.

  7. Metric qualities of the cognitive behavioral assessment for outcome evaluation to estimate psychological treatment effects.

    Science.gov (United States)

    Bertolotti, Giorgio; Michielin, Paolo; Vidotto, Giulio; Sanavio, Ezio; Bottesi, Gioia; Bettinardi, Ornella; Zotti, Anna Maria

    2015-01-01

    Cognitive behavioral assessment for outcome evaluation was developed to evaluate psychological treatment interventions, especially for counseling and psychotherapy. It is made up of 80 items and five scales: anxiety, well-being, perception of positive change, depression, and psychological distress. The aim of the study was to present the metric qualities and to show validity and reliability of the five constructs of the questionnaire both in nonclinical and clinical subjects. Four steps were completed to assess reliability and factor structure: criterion-related and concurrent validity, responsiveness, and convergent-divergent validity. A nonclinical group of 269 subjects was enrolled, as was a clinical group comprising 168 adults undergoing psychotherapy and psychological counseling provided by the Italian public health service. Cronbach's alphas were between 0.80 and 0.91 for the clinical sample and between 0.74 and 0.91 in the nonclinical one. We observed an excellent structural validity for the five interrelated dimensions. The clinical group showed higher scores in the anxiety, depression, and psychological distress scales, as well as lower scores in well-being and perception of positive change scales than those observed in the nonclinical group. Responsiveness was large for the anxiety, well-being, and depression scales; the psychological distress and perception of positive change scales showed a moderate effect. The questionnaire showed excellent psychometric properties, thus demonstrating that the questionnaire is a good evaluative instrument, with which to assess pre- and post-treatment outcomes.

  8. Theoretical and experimental studies of single event effect induced by atmospheric muons on nano-metric technologies

    International Nuclear Information System (INIS)

    Li Cavoli, P.

    2016-01-01

    This study concerns the domain of the microelectronics. It consists in the study of the impact of the 3D morphology of the energy deposit on the Single Event Effect (SEE) modeling, induced by atmospheric muons. Over a first phase, the approach has consisted in the modeling of the energy deposit induced by protons in nano-metric volumes. For that purpose the use of the Monte Carlo code GEANT4 has allowed us to simulate and stock in a database the tracks characteristics of the energy deposit induced by protons. Once the approach validated for the protons, simulations of the energy deposit induced by muons have been realized. A CCD camera has been used in order to measure the radiative atmospheric environment and to constrain the modeling of the energy deposit induced by muons. This study highlights and quantify the contribution of the radial distribution of the energy deposit induced by protons in nano-metric volumes for the SEE prediction. On the other hand, the study shows that the contribution of the radial distribution of the energy deposit induced by muons in nano-metric volumes has a negligible impact on the SEE modeling. It will be interesting to realize measurements of the energy deposit induced by muons in nano-metric technologies under particle accelerator. This will allow to bring experimental data still nonexistent necessary to the development of new physical models more accurate on the modeling of the energy deposit induced by muons. (author)

  9. Metrication manual

    International Nuclear Information System (INIS)

    Harper, A.F.A.; Digby, R.B.; Thong, S.P.; Lacey, F.

    1978-04-01

    In April 1978 a meeting of senior metrication officers convened by the Commonwealth Science Council of the Commonwealth Secretariat, was held in London. The participants were drawn from Australia, Bangladesh, Britain, Canada, Ghana, Guyana, India, Jamaica, Papua New Guinea, Solomon Islands and Trinidad and Tobago. Among other things, the meeting resolved to develop a set of guidelines to assist countries to change to SI and to compile such guidelines in the form of a working manual

  10. Distributed series resistance effects in solar cells

    DEFF Research Database (Denmark)

    Nielsen, Lars Drud

    1982-01-01

    A mathematical treatment is presented of the effects of one-dimensional distributed series resistance in solar cells. A general perturbation theory is developed, including consistently the induced spatial variation of diode current density and leading to a first-order equivalent lumped resistance...

  11. Fault Management Metrics

    Science.gov (United States)

    Johnson, Stephen B.; Ghoshal, Sudipto; Haste, Deepak; Moore, Craig

    2017-01-01

    This paper describes the theory and considerations in the application of metrics to measure the effectiveness of fault management. Fault management refers here to the operational aspect of system health management, and as such is considered as a meta-control loop that operates to preserve or maximize the system's ability to achieve its goals in the face of current or prospective failure. As a suite of control loops, the metrics to estimate and measure the effectiveness of fault management are similar to those of classical control loops in being divided into two major classes: state estimation, and state control. State estimation metrics can be classified into lower-level subdivisions for detection coverage, detection effectiveness, fault isolation and fault identification (diagnostics), and failure prognosis. State control metrics can be classified into response determination effectiveness and response effectiveness. These metrics are applied to each and every fault management control loop in the system, for each failure to which they apply, and probabilistically summed to determine the effectiveness of these fault management control loops to preserve the relevant system goals that they are intended to protect.

  12. Patron Time-Use May Be an Effective Metric for Presenting Library Value to Policy Makers

    Directory of Open Access Journals (Sweden)

    Ann Glusker

    2016-04-01

    Full Text Available Objective – To test a metric for library use, that could be comparable to metrics used by competing government departments, for ease of understanding by policy makers. Design – Four types of data were collected and used: Time-diaries, exit surveys, gate counts, and circulation statistics. Setting – A large public library in British Columbia, Canada. Subjects – Time-diary subjects were 445 patrons checking out materials; exit survey subjects were 185 patrons leaving the library. Methods – A paper-based time diary, prototypes of which were tested, was given to patrons who checked out library materials during a one-week period. These patrons were charged with recording the use of the checked-out items during the entire three-week loan period. From this information, the average number of hours spent with various types of loaned material (print and audio/DVD was calculated. The average number of hours spent per item type was then applied to the circulation statistics for those items, across a month, to get a total of hours spent using all circulated material during that month. During the same one-week period of time-diary distribution, exit surveys were conducted by library staff with patrons leaving the library, asking them how long they had spent in the library during their current visit. The average number of minutes per visit was calculated and then applied to the gate count for the month, to get a total number of minutes/hours spent “resident” in the library that month. Adding the totals, a grand total of patron time-use hours was calculated. A monetary value was applied per hour, using the results of a contingent valuation study from Missoula, Montana (Dalenberg et al., 2004, in order to convert hours of library benefit into a dollar figure. Main Results – There was a 24% response rate for the time diaries (106/445. The diary entries yielded an average of 3.5 hours of time-use per print item, and 1.9 hours per DVD. The range for

  13. Characterizing Social Media Metrics of Scholarly Papers: The Effect of Document Properties and Collaboration Patterns

    Science.gov (United States)

    Haustein, Stefanie; Costas, Rodrigo; Larivière, Vincent

    2015-01-01

    A number of new metrics based on social media platforms—grouped under the term “altmetrics”—have recently been introduced as potential indicators of research impact. Despite their current popularity, there is a lack of information regarding the determinants of these metrics. Using publication and citation data from 1.3 million papers published in 2012 and covered in Thomson Reuters’ Web of Science as well as social media counts from Altmetric.com, this paper analyses the main patterns of five social media metrics as a function of document characteristics (i.e., discipline, document type, title length, number of pages and references) and collaborative practices and compares them to patterns known for citations. Results show that the presence of papers on social media is low, with 21.5% of papers receiving at least one tweet, 4.7% being shared on Facebook, 1.9% mentioned on blogs, 0.8% found on Google+ and 0.7% discussed in mainstream media. By contrast, 66.8% of papers have received at least one citation. Our findings show that both citations and social media metrics increase with the extent of collaboration and the length of the references list. On the other hand, while editorials and news items are seldom cited, it is these types of document that are the most popular on Twitter. Similarly, while longer papers typically attract more citations, an opposite trend is seen on social media platforms. Finally, contrary to what is observed for citations, it is papers in the Social Sciences and humanities that are the most often found on social media platforms. On the whole, these findings suggest that factors driving social media and citations are different. Therefore, social media metrics cannot actually be seen as alternatives to citations; at most, they may function as complements to other type of indicators. PMID:25780916

  14. Characterizing social media metrics of scholarly papers: the effect of document properties and collaboration patterns.

    Science.gov (United States)

    Haustein, Stefanie; Costas, Rodrigo; Larivière, Vincent

    2015-01-01

    A number of new metrics based on social media platforms--grouped under the term "altmetrics"--have recently been introduced as potential indicators of research impact. Despite their current popularity, there is a lack of information regarding the determinants of these metrics. Using publication and citation data from 1.3 million papers published in 2012 and covered in Thomson Reuters' Web of Science as well as social media counts from Altmetric.com, this paper analyses the main patterns of five social media metrics as a function of document characteristics (i.e., discipline, document type, title length, number of pages and references) and collaborative practices and compares them to patterns known for citations. Results show that the presence of papers on social media is low, with 21.5% of papers receiving at least one tweet, 4.7% being shared on Facebook, 1.9% mentioned on blogs, 0.8% found on Google+ and 0.7% discussed in mainstream media. By contrast, 66.8% of papers have received at least one citation. Our findings show that both citations and social media metrics increase with the extent of collaboration and the length of the references list. On the other hand, while editorials and news items are seldom cited, it is these types of document that are the most popular on Twitter. Similarly, while longer papers typically attract more citations, an opposite trend is seen on social media platforms. Finally, contrary to what is observed for citations, it is papers in the Social Sciences and humanities that are the most often found on social media platforms. On the whole, these findings suggest that factors driving social media and citations are different. Therefore, social media metrics cannot actually be seen as alternatives to citations; at most, they may function as complements to other type of indicators.

  15. The International Safeguards Technology Base: How is the Patient Doing? An Exploration of Effective Metrics

    International Nuclear Information System (INIS)

    Schanfein, Mark J.; Gouveia, Fernando S.

    2010-01-01

    The term 'Technology Base' is commonly used but what does it mean? Is there a common understanding of the components that comprise a technology base? Does a formal process exist to assess the health of a given technology base? These are important questions the relevance of which is even more pressing given the USDOE/NNSA initiatives to strengthen the safeguards technology base through investments in research and development and human capital development. Accordingly, the authors will establish a high-level framework to define and understand what comprises a technology base. Potential goal-driven metrics to assess the health of a technology base will also be explored, such as linear demographics and resource availability, in the hope that they can be used to better understand and improve the health of the U.S. safeguards technology base. Finally, through the identification of such metrics, the authors will offer suggestions and highlight choices for addressing potential shortfalls.

  16. The International Safeguards Technology Base: How is the Patient Doing? An Exploration of Effective Metrics

    Energy Technology Data Exchange (ETDEWEB)

    Schanfein, Mark J; Gouveia, Fernando S

    2010-07-01

    The term “Technology Base” is commonly used but what does it mean? Is there a common understanding of the components that comprise a technology base? Does a formal process exist to assess the health of a given technology base? These are important questions the relevance of which is even more pressing given the USDOE/NNSA initiatives to strengthen the safeguards technology base through investments in research & development and human capital development. Accordingly, the authors will establish a high-level framework to define and understand what comprises a technology base. Potential goal-driven metrics to assess the health of a technology base will also be explored, such as linear demographics and resource availability, in the hope that they can be used to better understand and improve the health of the U.S. safeguards technology base. Finally, through the identification of such metrics, the authors will offer suggestions and highlight choices for addressing potential shortfalls.

  17. Wave function of the Universe, preferred reference frame effects and metric signature transition

    International Nuclear Information System (INIS)

    Ghaffarnejad, Hossein

    2015-01-01

    Gravitational model of non-minimally coupled Brans Dicke (BD) scalar field 0 with dynamical unit time-like four vector field is used to study flat Robertson Walker (RW) cosmology in the presence of variable cosmological parameter V (ϕ) = Λϕ. Aim of the paper is to seek cosmological models which exhibit metric signature transition. The problem is studied in both classical and quantum cosmological approach with large values of BD parameter ω >> 1. Scale factor of RW metric is obtained as which describes nonsingular inflationary universe in Lorentzian signature sector. Euclidean signature sector of our solution describes a re-collapsing universe and is obtained from analytic continuation of the Lorentzian sector by exchanging . Dynamical vector field together with the BD scalar field are treated as fluid with time dependent barotropic index. They have regular (dark) matter dominance in the Euclidean (Lorentzian) sector. We solved Wheeler De Witt (WD) quantum wave equation of the cosmological system. Assuming a discrete non-zero ADM mass we obtained solutions of the WD equation as simple harmonic quantum Oscillator eigen functionals described by Hermite polynomials. Absolute values of these eigen functionals have nonzero values on the hypersurface in which metric field has signature degeneracy. Our eigen functionals describe nonzero probability of the space time with Lorentzian (Euclidean) signature for . Maximal probability corresponds to the ground state j = 0. (paper)

  18. Deep Transfer Metric Learning.

    Science.gov (United States)

    Junlin Hu; Jiwen Lu; Yap-Peng Tan; Jie Zhou

    2016-12-01

    Conventional metric learning methods usually assume that the training and test samples are captured in similar scenarios so that their distributions are assumed to be the same. This assumption does not hold in many real visual recognition applications, especially when samples are captured across different data sets. In this paper, we propose a new deep transfer metric learning (DTML) method to learn a set of hierarchical nonlinear transformations for cross-domain visual recognition by transferring discriminative knowledge from the labeled source domain to the unlabeled target domain. Specifically, our DTML learns a deep metric network by maximizing the inter-class variations and minimizing the intra-class variations, and minimizing the distribution divergence between the source domain and the target domain at the top layer of the network. To better exploit the discriminative information from the source domain, we further develop a deeply supervised transfer metric learning (DSTML) method by including an additional objective on DTML, where the output of both the hidden layers and the top layer are optimized jointly. To preserve the local manifold of input data points in the metric space, we present two new methods, DTML with autoencoder regularization and DSTML with autoencoder regularization. Experimental results on face verification, person re-identification, and handwritten digit recognition validate the effectiveness of the proposed methods.

  19. Field installation versus local integration of photovoltaic systems and their effect on energy evaluation metrics

    International Nuclear Information System (INIS)

    Halasah, Suleiman A.; Pearlmutter, David; Feuermann, Daniel

    2013-01-01

    In this study we employ Life-Cycle Assessment to evaluate the energy-related impacts of photovoltaic systems at different scales of integration, in an arid region with especially high solar irradiation. Based on the electrical output and embodied energy of a selection of fixed and tracking systems and including concentrator photovoltaic (CPV) and varying cell technology, we calculate a number of energy evaluation metrics, including the energy payback time (EPBT), energy return factor (ERF), and life-cycle CO 2 emissions offset per unit aperture and land area. Studying these metrics in the context of a regionally limited setting, it was found that utilizing existing infrastructure such as existing building roofs and shade structures does significantly reduce the embodied energy requirements (by 20–40%) and in turn the EPBT of flat-plate PV systems due to the avoidance of energy-intensive balance of systems (BOS) components like foundations. Still, high-efficiency CPV field installations were found to yield the shortest EPBT, the highest ERF and the largest life-cycle CO 2 offsets—under the condition that land availability is not a limitation. A greater life-cycle energy return and carbon offset per unit land area is yielded by locally-integrated non-concentrating systems, despite their lower efficiency per unit module area. - Highlights: ► We evaluate life-cycle energy impacts of PV systems at different scales. ► We calculate the energy payback time, return factor and CO 2 emissions offset. ► Utilizing existing structures significantly improves metrics of flat-plate PV. ► High-efficiency CPV installations yield best return and offset per aperture area. ► Locally-integrated flat-plate systems yield best return and offset per land area.

  20. The proposed 'concordance-statistic for benefit' provided a useful metric when modeling heterogeneous treatment effects.

    Science.gov (United States)

    van Klaveren, David; Steyerberg, Ewout W; Serruys, Patrick W; Kent, David M

    2018-02-01

    Clinical prediction models that support treatment decisions are usually evaluated for their ability to predict the risk of an outcome rather than treatment benefit-the difference between outcome risk with vs. without therapy. We aimed to define performance metrics for a model's ability to predict treatment benefit. We analyzed data of the Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) trial and of three recombinant tissue plasminogen activator trials. We assessed alternative prediction models with a conventional risk concordance-statistic (c-statistic) and a novel c-statistic for benefit. We defined observed treatment benefit by the outcomes in pairs of patients matched on predicted benefit but discordant for treatment assignment. The 'c-for-benefit' represents the probability that from two randomly chosen matched patient pairs with unequal observed benefit, the pair with greater observed benefit also has a higher predicted benefit. Compared to a model without treatment interactions, the SYNTAX score II had improved ability to discriminate treatment benefit (c-for-benefit 0.590 vs. 0.552), despite having similar risk discrimination (c-statistic 0.725 vs. 0.719). However, for the simplified stroke-thrombolytic predictive instrument (TPI) vs. the original stroke-TPI, the c-for-benefit (0.584 vs. 0.578) was similar. The proposed methodology has the potential to measure a model's ability to predict treatment benefit not captured with conventional performance metrics. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. The metric system: An introduction

    Energy Technology Data Exchange (ETDEWEB)

    Lumley, S.M.

    1995-05-01

    On July 13, 1992, Deputy Director Duane Sewell restated the Laboratory`s policy on conversion to the metric system which was established in 1974. Sewell`s memo announced the Laboratory`s intention to continue metric conversion on a reasonable and cost effective basis. Copies of the 1974 and 1992 Administrative Memos are contained in the Appendix. There are three primary reasons behind the Laboratory`s conversion to the metric system. First, Public Law 100-418, passed in 1988, states that by the end of fiscal year 1992 the Federal Government must begin using metric units in grants, procurements, and other business transactions. Second, on July 25, 1991, President George Bush signed Executive Order 12770 which urged Federal agencies to expedite conversion to metric units. Third, the contract between the University of California and the Department of Energy calls for the Laboratory to convert to the metric system. Thus, conversion to the metric system is a legal requirement and a contractual mandate with the University of California. Public Law 100-418 and Executive Order 12770 are discussed in more detail later in this section, but first they examine the reasons behind the nation`s conversion to the metric system. The second part of this report is on applying the metric system.

  2. The metric system: An introduction

    Science.gov (United States)

    Lumley, Susan M.

    On 13 Jul. 1992, Deputy Director Duane Sewell restated the Laboratory's policy on conversion to the metric system which was established in 1974. Sewell's memo announced the Laboratory's intention to continue metric conversion on a reasonable and cost effective basis. Copies of the 1974 and 1992 Administrative Memos are contained in the Appendix. There are three primary reasons behind the Laboratory's conversion to the metric system. First, Public Law 100-418, passed in 1988, states that by the end of fiscal year 1992 the Federal Government must begin using metric units in grants, procurements, and other business transactions. Second, on 25 Jul. 1991, President George Bush signed Executive Order 12770 which urged Federal agencies to expedite conversion to metric units. Third, the contract between the University of California and the Department of Energy calls for the Laboratory to convert to the metric system. Thus, conversion to the metric system is a legal requirement and a contractual mandate with the University of California. Public Law 100-418 and Executive Order 12770 are discussed in more detail later in this section, but first they examine the reasons behind the nation's conversion to the metric system. The second part of this report is on applying the metric system.

  3. Engineering performance metrics

    Science.gov (United States)

    Delozier, R.; Snyder, N.

    1993-03-01

    Implementation of a Total Quality Management (TQM) approach to engineering work required the development of a system of metrics which would serve as a meaningful management tool for evaluating effectiveness in accomplishing project objectives and in achieving improved customer satisfaction. A team effort was chartered with the goal of developing a system of engineering performance metrics which would measure customer satisfaction, quality, cost effectiveness, and timeliness. The approach to developing this system involved normal systems design phases including, conceptual design, detailed design, implementation, and integration. The lessons teamed from this effort will be explored in this paper. These lessons learned may provide a starting point for other large engineering organizations seeking to institute a performance measurement system accomplishing project objectives and in achieving improved customer satisfaction. To facilitate this effort, a team was chartered to assist in the development of the metrics system. This team, consisting of customers and Engineering staff members, was utilized to ensure that the needs and views of the customers were considered in the development of performance measurements. The development of a system of metrics is no different than the development of any type of system. It includes the steps of defining performance measurement requirements, measurement process conceptual design, performance measurement and reporting system detailed design, and system implementation and integration.

  4. Re-examining the effect of low and intermediate mode number perturbations on Ignition Metrics Scaling Laws

    Science.gov (United States)

    Malka, Elad; Shvarts, Dov

    2017-10-01

    We re-examine the way 2/3D effects on scaling laws for ignition metrics, such as the generalized Lawson Criterion (GLC) and the Ignition Threshold Factor (ITF). These scaling laws were derived for 1D symmetrical case and 2/3D perturbations [Hann et al. PoP 2010; Lindl et al., PoP 2014; Betti et al., PoP 2010]. The main cause for the difference between the 1D and the 2/3D scaling laws in those works, is heat conduction losses from the hot-spot bubbles to the cold shell [Kishony and Shvarts, PoP 2001]. This ``dry out'' of the bubbles is the dominant mechanism for intermediate mode number perturbations (6hot spot. These two effects do not have an effective 1D analogue and therefore needs a more complicated model. A consistent extension of the ignition metrics for l <=6, accounting for both energy loss mechanisms, will be presented and compared with previous models and results. This work was supported by the LLNL under subcontract B614207.

  5. A Health-Based Metric for Evaluating the Effectiveness of Noise Barrier Mitigation Associated With Transport Infrastructure Noise

    Directory of Open Access Journals (Sweden)

    Geoffrey P Prendergast

    2017-01-01

    Full Text Available Introduction: This study examines the use of the number of night-time sleep disturbances as a health-based metric to assess the cost effectiveness of rail noise mitigation strategies for situations, wherein high-intensity noises dominate such as freight train pass-bys and wheel squeal. Materials and Methods: Twenty residential properties adjacent to the existing and proposed rail tracks in a noise catchment area of the Epping to Thornleigh Third Track project were used as a case study. Awakening probabilities were calculated for individual’s awakening 1, 3 and 5 times a night when subjected to 10 independent freight train pass-by noise events using internal maximum sound pressure levels (LAFmax. Results: Awakenings were predicted using a random intercept multivariate logistic regression model. With source mitigation in place, the majority of the residents were still predicted to be awoken at least once per night (median 88.0%, although substantial reductions in the median probabilities of awakening three and five times per night from 50.9 to 29.4% and 9.2 to 2.7%, respectively, were predicted. This resulted in a cost-effective estimate of 7.6–8.8 less people being awoken at least three times per night per A$1 million spent on noise barriers. Conclusion: The study demonstrates that an easily understood metric can be readily used to assist making decisions related to noise mitigation for large-scale transport projects.

  6. Next-Generation Metrics: Responsible Metrics & Evaluation for Open Science

    Energy Technology Data Exchange (ETDEWEB)

    Wilsdon, J.; Bar-Ilan, J.; Peters, I.; Wouters, P.

    2016-07-01

    Metrics evoke a mixed reaction from the research community. A commitment to using data to inform decisions makes some enthusiastic about the prospect of granular, real-time analysis o of research and its wider impacts. Yet we only have to look at the blunt use of metrics such as journal impact factors, h-indices and grant income targets, to be reminded of the pitfalls. Some of the most precious qualities of academic culture resist simple quantification, and individual indicators often struggle to do justice to the richness and plurality of research. Too often, poorly designed evaluation criteria are “dominating minds, distorting behaviour and determining careers (Lawrence, 2007).” Metrics hold real power: they are constitutive of values, identities and livelihoods. How to exercise that power to more positive ends has been the focus of several recent and complementary initiatives, including the San Francisco Declaration on Research Assessment (DORA1), the Leiden Manifesto2 and The Metric Tide3 (a UK government review of the role of metrics in research management and assessment). Building on these initiatives, the European Commission, under its new Open Science Policy Platform4, is now looking to develop a framework for responsible metrics for research management and evaluation, which can be incorporated into the successor framework to Horizon 2020. (Author)

  7. Software Quality Assurance Metrics

    Science.gov (United States)

    McRae, Kalindra A.

    2004-01-01

    Software Quality Assurance (SQA) is a planned and systematic set of activities that ensures conformance of software life cycle processes and products conform to requirements, standards and procedures. In software development, software quality means meeting requirements and a degree of excellence and refinement of a project or product. Software Quality is a set of attributes of a software product by which its quality is described and evaluated. The set of attributes includes functionality, reliability, usability, efficiency, maintainability, and portability. Software Metrics help us understand the technical process that is used to develop a product. The process is measured to improve it and the product is measured to increase quality throughout the life cycle of software. Software Metrics are measurements of the quality of software. Software is measured to indicate the quality of the product, to assess the productivity of the people who produce the product, to assess the benefits derived from new software engineering methods and tools, to form a baseline for estimation, and to help justify requests for new tools or additional training. Any part of the software development can be measured. If Software Metrics are implemented in software development, it can save time, money, and allow the organization to identify the caused of defects which have the greatest effect on software development. The summer of 2004, I worked with Cynthia Calhoun and Frank Robinson in the Software Assurance/Risk Management department. My task was to research and collect, compile, and analyze SQA Metrics that have been used in other projects that are not currently being used by the SA team and report them to the Software Assurance team to see if any metrics can be implemented in their software assurance life cycle process.

  8. Effects of toroidicity on resistive tearing modes

    International Nuclear Information System (INIS)

    Izzo, R.; Monticello, D.A.; Manickam, J.; Strauss, H.R.; Grimm, R.; McGuire, K.

    1983-03-01

    A reduced set of resistive MHD equations is solved numerically in three dimensions to study the stability of tokamak plasmas. Toroidal effects are included self-consistently to leading and next order in inverse aspect ratio, epsilon. The equations satisfy an energy integral. In addition, the momentum equation yields the Grad-Shafranov equation correct to all orders in epsilon. Low beta plasma are studied using several different q-profiles. In all cases, the linear growth rates are reduced by finite toroidicity. Excellent agreement with resistive PEST is obtianed. In some cases, toroidal effects lead to complete stabilization of the mode. Nonlinear results show smaller saturated island widths for finite aspect ratio compared to the cylindrical limit. If the current channel is wide enough so as to produce steep gradients towards the outside of the plasma, both the finite aspect ratio cases and cylindrical cases disrupt

  9. Electropolishing effect on roughness metrics of ground stainless steel: a length scale study

    Science.gov (United States)

    Nakar, Doron; Harel, David; Hirsch, Baruch

    2018-03-01

    Electropolishing is a widely-used electrochemical surface finishing process for metals. The electropolishing of stainless steel has vast commercial application, such as improving corrosion resistance, improving cleanness, and brightening. The surface topography characterization is performed using several techniques with different lateral resolutions and length scales, from atomic force microscopy in the nano-scale (filter are adopted. While the commonly used roughness amplitude parameters (Ra, Rq and Rz) fail to characterize electropolished textures, the root mean square slope (RΔq) is found to better describe the electropolished surfaces and to be insensitive to scale.

  10. Rate effects in resistive plate chambers

    International Nuclear Information System (INIS)

    Lippmann, C.; Riegler, W.; Kalweit, A.

    2006-01-01

    The resistive plates in RPCs cause a drop of the electric field in the gas gap at high particle rates or large gas gain, which affects efficiency and time resolution. This effect is typically estimated by assuming the particle flux to be a DC current that causes a voltage drop when it passes through the resistive plate. In an improved model by Abbrescia (Nucl. Instr. Meth. A 533 (2004) 7), the fluctuation of the field in the gas gap is modelled by assuming that the avalanche partially discharges a small capacitor which gets recharged with a time constant characteristic for the given RPC. In our approach, the effect is calculated by using the exact analytic solution for the time dependent electric field of a point charge sitting on the surface of a resistive plate in an RPC. This is, by definition, the best possible approximation to reality. The solution is obtained using the quasi-static approximation of Maxwell's equations. The formulas are presented as integral representations with 'cured' integrands, which allow easy numerical evaluation for Monte Carlo simulations. The solutions show that the charges in RPCs are 'destroyed' with a continuous distribution of time constants which are related in a very intuitive way to some limiting cases. Using these formulas we present a Monte Carlo simulation of rate effects, proving the applicability of this approach. Finally, we compare the Monte Carlo results to analytical calculations, similar to the ones proposed by Gonzalez-Diaz et al. (see proceedings of this conference)

  11. Menopause: highlighting the effects of resistance training.

    Science.gov (United States)

    Leite, R D; Prestes, J; Pereira, G B; Shiguemoto, G E; Perez, S E A

    2010-11-01

    The increase in lifespan and in the proportion of elderly women has increased the focus on menopause induced physiological alterations. These modifications are associated with the elevated risk of several pathologies such as cardiovascular disease, diabetes, obesity, hypertension, dyslipidemia, non-alcoholic fat liver disease, among others. Because of estrogen levels decline, many tissue and organs (muscular, bone, adipose tissue and liver) are affected. Additionally, body composition suffers important modifications. In this sense, there is a growing body of concern in understanding the physiological mechanisms involved and establishing strategies to prevent and reverse the effects of menopause. The hormone reposition therapy, diet and physical exercise have been recommended. Among the diverse exercise modalities, resistance training is not commonly used as a therapeutic intervention in the treatment of menopause. Thus, the aim of this review was to analyze the physiological alterations on several organs and systems induced by menopause and ovariectomy (experimental model to reproduce menopause), as well as, to study the effects of resistance training in preventing and reverting these modifications. In conclusion, resistance training promotes beneficial effects on several organs and systems, mainly, on muscular, bone and adipose tissue, allowing for a better quality of life in this population.

  12. Metrics of quantum states

    International Nuclear Information System (INIS)

    Ma Zhihao; Chen Jingling

    2011-01-01

    In this work we study metrics of quantum states, which are natural generalizations of the usual trace metric and Bures metric. Some useful properties of the metrics are proved, such as the joint convexity and contractivity under quantum operations. Our result has a potential application in studying the geometry of quantum states as well as the entanglement detection.

  13. The effect of electrode contact resistance and capacitive coupling on Complex Resistivity measurements

    DEFF Research Database (Denmark)

    Ingeman-Nielsen, Thomas

    2006-01-01

    The effect of electrode contact resistance and capacitive coupling on complex resistivity (CR) measurements is studied in this paper. An equivalent circuit model for the receiver is developed to describe the effects. The model shows that CR measurements are severely affected even at relatively lo...... with the contact resistance artificially increased by resistors. The results emphasize the importance of keeping contact resistance low in CR measurements....

  14. $\\eta$-metric structures

    OpenAIRE

    Gaba, Yaé Ulrich

    2017-01-01

    In this paper, we discuss recent results about generalized metric spaces and fixed point theory. We introduce the notion of $\\eta$-cone metric spaces, give some topological properties and prove some fixed point theorems for contractive type maps on these spaces. In particular we show that theses $\\eta$-cone metric spaces are natural generalizations of both cone metric spaces and metric type spaces.

  15. Multi-site Study of Diffusion Metric Variability: Characterizing the Effects of Site, Vendor, Field Strength, and Echo Time using the Histogram Distance

    Science.gov (United States)

    Helmer, K. G.; Chou, M-C.; Preciado, R. I.; Gimi, B.; Rollins, N. K.; Song, A.; Turner, J.; Mori, S.

    2016-01-01

    MRI-based multi-site trials now routinely include some form of diffusion-weighted imaging (DWI) in their protocol. These studies can include data originating from scanners built by different vendors, each with their own set of unique protocol restrictions, including restrictions on the number of available gradient directions, whether an externally-generated list of gradient directions can be used, and restrictions on the echo time (TE). One challenge of multi-site studies is to create a common imaging protocol that will result in a reliable and accurate set of diffusion metrics. The present study describes the effect of site, scanner vendor, field strength, and TE on two common metrics: the first moment of the diffusion tensor field (mean diffusivity, MD), and the fractional anisotropy (FA). We have shown in earlier work that ROI metrics and the mean of MD and FA histograms are not sufficiently sensitive for use in site characterization. Here we use the distance between whole brain histograms of FA and MD to investigate within- and between-site effects. We concluded that the variability of DTI metrics due to site, vendor, field strength, and echo time could influence the results in multi-center trials and that histogram distance is sensitive metrics for each of these variables. PMID:27350723

  16. Multi-site Study of Diffusion Metric Variability: Characterizing the Effects of Site, Vendor, Field Strength, and Echo Time using the Histogram Distance.

    Science.gov (United States)

    Helmer, K G; Chou, M-C; Preciado, R I; Gimi, B; Rollins, N K; Song, A; Turner, J; Mori, S

    2016-02-27

    MRI-based multi-site trials now routinely include some form of diffusion-weighted imaging (DWI) in their protocol. These studies can include data originating from scanners built by different vendors, each with their own set of unique protocol restrictions, including restrictions on the number of available gradient directions, whether an externally-generated list of gradient directions can be used, and restrictions on the echo time (TE). One challenge of multi-site studies is to create a common imaging protocol that will result in a reliable and accurate set of diffusion metrics. The present study describes the effect of site, scanner vendor, field strength, and TE on two common metrics: the first moment of the diffusion tensor field (mean diffusivity, MD), and the fractional anisotropy (FA). We have shown in earlier work that ROI metrics and the mean of MD and FA histograms are not sufficiently sensitive for use in site characterization. Here we use the distance between whole brain histograms of FA and MD to investigate within- and between-site effects. We concluded that the variability of DTI metrics due to site, vendor, field strength, and echo time could influence the results in multi-center trials and that histogram distance is sensitive metrics for each of these variables.

  17. FY 2011 4th Quarter Metric: Estimate of Future Aerosol Direct and Indirect Effects

    Energy Technology Data Exchange (ETDEWEB)

    Koch, D

    2011-09-21

    The global and annual mean aerosol direct and indirect effects, relative to 1850 conditions, estimated from CESM simulations are 0.02 W m-2 and -0.39 W m-2, respectively, for emissions in year 2100 under the IPCC RCP8.5 scenario. The indirect effect is much smaller than that for 2000 emissions because of much smaller SO2 emissions in 2100; the direct effects are small due to compensation between warming by black carbon and cooling by sulfate.

  18. Number and density discrimination rely on a common metric: Similar psychophysical effects of size, contrast, and divided attention.

    Science.gov (United States)

    Tibber, Marc S; Greenwood, John A; Dakin, Steven C

    2012-06-04

    While observers are adept at judging the density of elements (e.g., in a random-dot image), it has recently been proposed that they also have an independent visual sense of number. To test the independence of number and density discrimination, we examined the effects of manipulating stimulus structure (patch size, element size, contrast, and contrast-polarity) and available attentional resources on both judgments. Five observers made a series of two-alternative, forced-choice discriminations based on the relative numerosity/density of two simultaneously presented patches containing 16-1,024 Gaussian blobs. Mismatches of patch size and element size (across reference and test) led to bias and reduced sensitivity in both tasks, whereas manipulations of contrast and contrast-polarity had varied effects on observers, implying differing strategies. Nonetheless, the effects reported were consistent across density and number judgments, the only exception being when luminance cues were made available. Finally, density and number judgment were similarly impaired by attentional load in a dual-task experiment. These results are consistent with a common underlying metric to density and number judgments, with the caveat that additional cues may be exploited when they are available.

  19. Using Social Network Metrics to Assess the Effectiveness of Broad Based Admission Practices

    Science.gov (United States)

    Dawson, Shane; Macfadyen, Leah; Lockyer, Lori; Mazzochi-Jones, David

    2011-01-01

    Notions of what it is to be knowledgeable and skilled in one's profession have evolved in recent decades. For instance, medical practitioners are expected to think critically and creatively, communicate effectively, and to be a professional and community leader. While these attributes have always been well regarded, it is only relatively recently…

  20. Effects of Traditional Advertising and Social Messages on Brand-Building Metrics and Customer Acquisition

    NARCIS (Netherlands)

    De Vries, Lisette; Gensler, Sonja; Leeflang, Pieter

    This study examines the relative effectiveness of traditional advertising, impressions generated through firm-to-consumer (F2C) messages on Facebook, and the volume and valence of consumer-to-consumer (C2C) messages on Twitter and web forums for brand-building and customer acquisition efforts. The

  1. Chronic effects of temperature on mortality in the Southeastern USA using satellite-based exposure metrics

    Science.gov (United States)

    Shi, Liuhua; Liu, Pengfei; Wang, Yan; Zanobetti, Antonella; Kosheleva, Anna; Koutrakis, Petros; Schwartz, Joel

    2016-07-01

    Climate change may affect human health, particularly for elderly individuals who are vulnerable to temperature changes. While many studies have investigated the acute effects of heat, only a few have dealt with the chronic ones. We have examined the effects of seasonal temperatures on survival of the elderly in the Southeastern USA, where a large fraction of subpopulation resides. We found that both seasonal mean temperature and its standard deviation (SD) affected long-term survival among the 13 million Medicare beneficiaries (aged 65+) in this region during 2000-2013. A 1 °C increase in summer mean temperature corresponded to an increase of 2.5% in death rate. Whereas, 1 °C increase in winter mean temperature was associated with a decrease of 1.5%. Increases in seasonal temperature SD also influence mortality. We decomposed seasonal mean temperature and its temperature SD into long-term geographic contrasts between ZIP codes and annual anomalies within ZIP code. Effect modifications by different subgroups were also examined to find out whether certain individuals are more vulnerable. Our findings will be critical to future efforts assessing health risks related to the future climate change.

  2. Analysing Parallel and Passive Web Browsing Behavior and its Effects on Website Metrics

    OpenAIRE

    von der Weth, Christian; Hauswirth, Manfred

    2014-01-01

    Getting deeper insights into the online browsing behavior of Web users has been a major research topic since the advent of the WWW. It provides useful information to optimize website design, Web browser design, search engines offerings, and online advertisement. We argue that new technologies and new services continue to have significant effects on the way how people browse the Web. For example, listening to music clips on YouTube or to a radio station on Last.fm does not require users to sit...

  3. Years-needed-to-treat to add 1 year of life: a new metric to estimate treatment effects in randomized trials

    DEFF Research Database (Denmark)

    Levy, Wayne C; Mozaffarian, Dariush; Linker, David T

    2009-01-01

    AIMS: A standard metric to estimate absolute treatment effects is numbers-needed-to-treat (NNT), which implicitly assumes that all benefits reverse at trial-end. However, in-trial survival benefits typically do not reverse until long after trial-end, so that NNT will substantially underestimate l...

  4. Kepler Planet Detection Metrics: Robovetter Completeness and Effectiveness for Data Release 25

    Science.gov (United States)

    Coughlin, Jeffrey L.

    2017-01-01

    calculate accurate occurrence rates, the completeness and effectiveness of the Robovetter must be characterized. We define these terms as applied to the Robovetter, following Thompson et al. (2017), as:1. Completeness: The fraction of transiting planets detected by the pipeline that are classified as planet candidates by the Robovetter.2. Effectiveness: The fraction of false positives detected by the pipeline that are classified as false positives by the Robovetter.The remainder of this document describes products that can be used to quantitatively assess Robovetter completeness and effectiveness for an arbitrary set of Kepler stars.

  5. Stability of nano-metric colloidal dispersions of titanium: effect of surface complexation

    International Nuclear Information System (INIS)

    Peyre, Veronique

    1996-01-01

    This research thesis reports the study of the adsorption of small organic molecules at the surface of nano-particles of mineral oxides (zirconia), and of its effects on the stability of the colloidal dispersion. Adsorption has been quantified by adsorption isotherms and surface titrations. Processes and mechanisms are thus discussed with respect to pH. The influence of various protecting molecules (acetyl acetone, but also acetic acid, citric acid and diethanolamine) has been studied, and notably highlighted the role of the outer face of the complexing agent in the assessment of reactions between particles which govern the compression and re-dispersability properties of protected dispersions. This study is performed by osmotic pressure measurements and by X-ray diffusion at small angles, completed by statistical mechanics calculations [fr

  6. Overall Bike Effectiveness as a Sustainability Metric for Bike Sharing Systems

    Directory of Open Access Journals (Sweden)

    Bernardo Nugroho Yahya

    2017-11-01

    Full Text Available Bike sharing systems (BSS have been widely accepted as an urban transport scheme in many cities around the world. The concept is recently expanded and followed by many cities to offer citizen a “green” and flexible transportation scheme in urban areas. Many works focus on the issues of bike availability while the bike performance, i.e., life cycle issues and its sustainability, for better management has been abandoned. As a consequence, mismanagement of BSS would lead to cost inefficiency and, the worst case, end with operation termination. This study proposes a design science approach by developing an Overall Bike Effectiveness (OBE framework. By incorporating the concept of overall equipment analysis (OEE, the proposed framework is used to measure the bike utilization. Accordingly, the OBE is extended into Theoretical OBE to measure the sustainability of the early-stage of BSS. The framework has been verified and evaluated using a real dataset of BSS. The proposed method provides valuable results for benchmarking, life cycle analysis, system expansion and strategy planning toward sustainability. The paper concludes with a discussion to show the impact of the proposed approach into the real practices of BSS including an outlook toward sustainability of BSS.

  7. METRIC context unit architecture

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, R.O.

    1988-01-01

    METRIC is an architecture for a simple but powerful Reduced Instruction Set Computer (RISC). Its speed comes from the simultaneous processing of several instruction streams, with instructions from the various streams being dispatched into METRIC's execution pipeline as they become available for execution. The pipeline is thus kept full, with a mix of instructions for several contexts in execution at the same time. True parallel programming is supported within a single execution unit, the METRIC Context Unit. METRIC's architecture provides for expansion through the addition of multiple Context Units and of specialized Functional Units. The architecture thus spans a range of size and performance from a single-chip microcomputer up through large and powerful multiprocessors. This research concentrates on the specification of the METRIC Context Unit at the architectural level. Performance tradeoffs made during METRIC's design are discussed, and projections of METRIC's performance are made based on simulation studies.

  8. Multi-site study of diffusion metric variability: effects of site, vendor, field strength, and echo time on regions-of-interest and histogram-bin analyses.

    Science.gov (United States)

    Helmer, K G; Chou, M-C; Preciado, R I; Gimi, B; Rollins, N K; Song, A; Turner, J; Mori, S

    2016-02-27

    It is now common for magnetic-resonance-imaging (MRI) based multi-site trials to include diffusion-weighted imaging (DWI) as part of the protocol. It is also common for these sites to possess MR scanners of different manufacturers, different software and hardware, and different software licenses. These differences mean that scanners may not be able to acquire data with the same number of gradient amplitude values and number of available gradient directions. Variability can also occur in achievable b-values and minimum echo times. The challenge of a multi-site study then, is to create a common protocol by understanding and then minimizing the effects of scanner variability and identifying reliable and accurate diffusion metrics. This study describes the effect of site, scanner vendor, field strength, and TE on two diffusion metrics: the first moment of the diffusion tensor field (mean diffusivity, MD), and the fractional anisotropy (FA) using two common analyses (region-of-interest and mean-bin value of whole brain histograms). The goal of the study was to identify sources of variability in diffusion-sensitized imaging and their influence on commonly reported metrics. The results demonstrate that the site, vendor, field strength, and echo time all contribute to variability in FA and MD, though to different extent. We conclude that characterization of the variability of DTI metrics due to site, vendor, field strength, and echo time is a worthwhile step in the construction of multi-center trials.

  9. Some Metric Properties of Planar Gaussian Free Field

    Science.gov (United States)

    Goswami, Subhajit

    In this thesis we study the properties of some metrics arising from two-dimensional Gaussian free field (GFF), namely the Liouville first-passage percolation (Liouville FPP), the Liouville graph distance and an effective resistance metric. In Chapter 1, we define these metrics as well as discuss the motivations for studying them. Roughly speaking, Liouville FPP is the shortest path metric in a planar domain D where the length of a path P is given by ∫Pe gammah(z)|dz| where h is the GFF on D and gamma > 0. In Chapter 2, we present an upper bound on the expected Liouville FPP distance between two typical points for small values of gamma (the near-Euclidean regime). A similar upper bound is derived in Chapter 3 for the Liouville graph distance which is, roughly, the minimal number of Euclidean balls with comparable Liouville quantum gravity (LQG) measure whose union contains a continuous path between two endpoints. Our bounds seem to be in disagreement with Watabiki's prediction (1993) on the random metric of Liouville quantum gravity in this regime. The contents of these two chapters are based on a joint work with Jian Ding. In Chapter 4, we derive some asymptotic estimates for effective resistances on a random network which is defined as follows. Given any gamma > 0 and for eta = {etav}v∈Z2 denoting a sample of the two-dimensional discrete Gaussian free field on Z2 pinned at the origin, we equip the edge ( u, v) with conductance egamma(etau + eta v). The metric structure of effective resistance plays a crucial role in our proof of the main result in Chapter 4. The primary motivation behind this metric is to understand the random walk on Z 2 where the edge (u, v) has weight egamma(etau + etav). Using the estimates from Chapter 4 we show in Chapter 5 that for almost every eta, this random walk is recurrent and that, with probability tending to 1 as T → infinity, the return probability at time 2T decays as T-1+o(1). In addition, we prove a version of subdiffusive

  10. Defining a Progress Metric for CERT RMM Improvement

    Science.gov (United States)

    2017-09-14

    REV-03.18.2016.0 Defining a Progress Metric for CERT-RMM Improvement Gregory Crabb Nader Mehravari David Tobar September 2017 TECHNICAL ...fendable resource allocation decisions. Technical metrics measure aspects of controls implemented through technology (systems, soft- ware, hardware...implementation metric would be the percentage of users who have received anti-phishing training . • Effectiveness/efficiency metrics measure whether

  11. Effects of atmospheric moisture on rock resistivity.

    Science.gov (United States)

    Alvarez, R.

    1973-01-01

    This study examines the changes in resistivity of rock samples as induced by atmospheric moisture. Experiments were performed on samples of hematitic sandstone, pyrite, and galena. The sandstone underwent a change in resistivity of four orders of magnitude when it was measured in a vacuum of 500 ntorr and in air of 37% relative humidity. Pyrite and galena showed no variations in resistivity when they were measured under the same conditions. These results, plus others obtained elsewhere, indicate that rocks of the resistive type are affected in their electrical properties by atmospheric moisture, whereas rocks of the conductive type are not. The experimental evidence obtained is difficult to reconcile with a model of aqueous electrolytic conduction on the sample surface. It is instead suggested that adsorbed water molecules alter the surface resistivity in a manner similar to that observed in semiconductors and insulators.

  12. Metric diffusion along foliations

    CERN Document Server

    Walczak, Szymon M

    2017-01-01

    Up-to-date research in metric diffusion along compact foliations is presented in this book. Beginning with fundamentals from the optimal transportation theory and the theory of foliations; this book moves on to cover Wasserstein distance, Kantorovich Duality Theorem, and the metrization of the weak topology by the Wasserstein distance. Metric diffusion is defined, the topology of the metric space is studied and the limits of diffused metrics along compact foliations are discussed. Essentials on foliations, holonomy, heat diffusion, and compact foliations are detailed and vital technical lemmas are proved to aide understanding. Graduate students and researchers in geometry, topology and dynamics of foliations and laminations will find this supplement useful as it presents facts about the metric diffusion along non-compact foliation and provides a full description of the limit for metrics diffused along foliation with at least one compact leaf on the two dimensions.

  13. Metric modular spaces

    CERN Document Server

    Chistyakov, Vyacheslav

    2015-01-01

    Aimed toward researchers and graduate students familiar with elements of functional analysis, linear algebra, and general topology; this book contains a general study of modulars, modular spaces, and metric modular spaces. Modulars may be thought of as generalized velocity fields and serve two important purposes: generate metric spaces in a unified manner and provide a weaker convergence, the modular convergence, whose topology is non-metrizable in general. Metric modular spaces are extensions of metric spaces, metric linear spaces, and classical modular linear spaces. The topics covered include the classification of modulars, metrizability of modular spaces, modular transforms and duality between modular spaces, metric  and modular topologies. Applications illustrated in this book include: the description of superposition operators acting in modular spaces, the existence of regular selections of set-valued mappings, new interpretations of spaces of Lipschitzian and absolutely continuous mappings, the existe...

  14. Frequency of Extreme Heat Event as a Surrogate Exposure Metric for Examining the Human Health Effects of Climate Change.

    Directory of Open Access Journals (Sweden)

    Crystal Romeo Upperman

    Full Text Available Epidemiological investigation of the impact of climate change on human health, particularly chronic diseases, is hindered by the lack of exposure metrics that can be used as a marker of climate change that are compatible with health data. Here, we present a surrogate exposure metric created using a 30-year baseline (1960-1989 that allows users to quantify long-term changes in exposure to frequency of extreme heat events with near unabridged spatial coverage in a scale that is compatible with national/state health outcome data. We evaluate the exposure metric by decade, seasonality, area of the country, and its ability to capture long-term changes in weather (climate, including natural climate modes. Our findings show that this generic exposure metric is potentially useful to monitor trends in the frequency of extreme heat events across varying regions because it captures long-term changes; is sensitive to the natural climate modes (ENSO events; responds well to spatial variability, and; is amenable to spatial/temporal aggregation, making it useful for epidemiological studies.

  15. Effect of Ampicillin, Streptomycin, Penicillin and Tetracycline on Metal Resistant and Non-Resistant Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Dagmar Chudobova

    2014-03-01

    Full Text Available There is an arising and concerning issue in the field of bacterial resistance, which is confirmed by the number of deaths associated with drug-resistant bacterial infections. The aim of this study was to compare the effects of antibiotics on Staphylococcus aureus non-resistant strain and strains resistant to cadmium or lead ions. Metal resistant strains were created by the gradual addition of 2 mM solution of metal ions (cadmium or lead to the S. aureus culture. An increasing antimicrobial effect of ampicillin, streptomycin, penicillin and tetracycline (0, 10, 25, 50, 75, 150, 225 and 300 µM on the resistant strains was observed using a method of growth curves. A significant growth inhibition (compared to control of cadmium resistant cells was observed in the presence of all the four different antibiotics. On the other hand, the addition of streptomycin and ampicillin did not inhibit the growth of lead resistant strain. Other antibiotics were still toxic to the bacterial cells. Significant differences in the morphology of cell walls were indicated by changes in the cell shape. Our data show that the presence of metal ions in the urban environment may contribute to the development of bacterial strain resistance to other substances including antibiotics, which would have an impact on public health.

  16. Effect of Ampicillin, Streptomycin, Penicillin and Tetracycline on Metal Resistant and Non-Resistant Staphylococcus aureus

    Science.gov (United States)

    Chudobova, Dagmar; Dostalova, Simona; Blazkova, Iva; Michalek, Petr; Ruttkay-Nedecky, Branislav; Sklenar, Matej; Nejdl, Lukas; Kudr, Jiri; Gumulec, Jaromir; Tmejova, Katerina; Konecna, Marie; Vaculovicova, Marketa; Hynek, David; Masarik, Michal; Kynicky, Jindrich; Kizek, Rene; Adam, Vojtech

    2014-01-01

    There is an arising and concerning issue in the field of bacterial resistance, which is confirmed by the number of deaths associated with drug-resistant bacterial infections. The aim of this study was to compare the effects of antibiotics on Staphylococcus aureus non-resistant strain and strains resistant to cadmium or lead ions. Metal resistant strains were created by the gradual addition of 2 mM solution of metal ions (cadmium or lead) to the S. aureus culture. An increasing antimicrobial effect of ampicillin, streptomycin, penicillin and tetracycline (0, 10, 25, 50, 75, 150, 225 and 300 µM) on the resistant strains was observed using a method of growth curves. A significant growth inhibition (compared to control) of cadmium resistant cells was observed in the presence of all the four different antibiotics. On the other hand, the addition of streptomycin and ampicillin did not inhibit the growth of lead resistant strain. Other antibiotics were still toxic to the bacterial cells. Significant differences in the morphology of cell walls were indicated by changes in the cell shape. Our data show that the presence of metal ions in the urban environment may contribute to the development of bacterial strain resistance to other substances including antibiotics, which would have an impact on public health. PMID:24651395

  17. Prognostic Performance Metrics

    Data.gov (United States)

    National Aeronautics and Space Administration — This chapter presents several performance metrics for offline evaluation of prognostics algorithms. A brief overview of different methods employed for performance...

  18. Overview of journal metrics

    Directory of Open Access Journals (Sweden)

    Kihong Kim

    2018-02-01

    Full Text Available Various kinds of metrics used for the quantitative evaluation of scholarly journals are reviewed. The impact factor and related metrics including the immediacy index and the aggregate impact factor, which are provided by the Journal Citation Reports, are explained in detail. The Eigenfactor score and the article influence score are also reviewed. In addition, journal metrics such as CiteScore, Source Normalized Impact per Paper, SCImago Journal Rank, h-index, and g-index are discussed. Limitations and problems that these metrics have are pointed out. We should be cautious to rely on those quantitative measures too much when we evaluate journals or researchers.

  19. Insecticide Resistance Reducing Effectiveness of Malaria Control

    Centers for Disease Control (CDC) Podcasts

    Malaria prevention is increasingly insecticide based. Dr. John Gimnig, an entomologist with the Division of Parasitic Diseases, CDC, discusses evidence that mosquito resistance to insecticides, which is measured in the laboratory, could compromise malaria prevention in the field.

  20. Short-term effects of various ozone metrics on cardiopulmonary function in chronic obstructive pulmonary disease patients: Results from a panel study in Beijing, China.

    Science.gov (United States)

    Li, Hongyu; Wu, Shaowei; Pan, Lu; Xu, Junhui; Shan, Jiao; Yang, Xuan; Dong, Wei; Deng, Furong; Chen, Yahong; Shima, Masayuki; Guo, Xinbiao

    2018-01-01

    Short-term exposure to ambient air pollution has been associated with lower pulmonary function and higher blood pressure (BP). However, controversy remains regarding the relationship between ambient multiple daily ozone (O 3 ) metrics and cardiopulmonary health outcomes, especially in the developing countries. To investigate and compare the short-term effects of various O 3 metrics on pulmonary function, fractional exhaled nitric oxide (FeNO) and BP in a panel study of COPD patients. We measured pulmonary function, FeNO and BP repeatedly in a total of 43 patients with COPD for 215 home visits. Daily hourly ambient O 3 concentrations were obtained from central-monitoring stations close to subject residences. We calculated various O 3 metrics [daily 1-h maximum (O 3 -1 h max), maximum 8-h average (O 3 -8 h max) and 24-h average (O 3 -24 h avg)] based on the hourly data. Daily indoor O 3 concentrations were estimated based on estimated indoor/outdoor O 3 ratios. Linear mixed-effects models were used to estimate associations of various O 3 metrics with cardiopulmonary function variables. An interquartile range (IQR) increase in ambient O 3 -8 h max (80.5 μg/m 3 , 5-d) was associated with a 5.9% (95%CI: -11.0%, -0.7%) reduction in forced expiratory volume in 1 s (FEV 1 ) and a 6.2% (95%CI: -10.9%, -1.5%) reduction in peak expiratory flow (PEF). However, there were no significant negative associations between ambient O 3 -1 h max, O 3 -24 h avg and FEV 1 , PEF. An IQR increase in ambient O 3 -1 h max (85.3 μg/m 3 , 6-d) was associated with a 6.7 mmHg (95%CI: 0.7, 12.7) increase in systolic BP. The estimated indoor O 3 were still significantly associated with reduction of FEV 1 and PEF. No significant associations were found between various O 3 metrics and FeNO. Our results provide clues for the adverse cardiopulmonary effects associated with various O 3 metrics in COPD patients and highlight that O 3 -8 h max was more closely associated with respiratory

  1. Metric adjusted skew information

    DEFF Research Database (Denmark)

    Hansen, Frank

    2008-01-01

    ) that vanishes for observables commuting with the state. We show that the skew information is a convex function on the manifold of states. It also satisfies other requirements, proposed by Wigner and Yanase, for an effective measure-of-information content of a state relative to a conserved observable. We...... establish a connection between the geometrical formulation of quantum statistics as proposed by Chentsov and Morozova and measures of quantum information as introduced by Wigner and Yanase and extended in this article. We show that the set of normalized Morozova-Chentsov functions describing the possible......We extend the concept of Wigner-Yanase-Dyson skew information to something we call "metric adjusted skew information" (of a state with respect to a conserved observable). This "skew information" is intended to be a non-negative quantity bounded by the variance (of an observable in a state...

  2. Leading Gainful Employment Metric Reporting

    Science.gov (United States)

    Powers, Kristina; MacPherson, Derek

    2016-01-01

    This chapter will address the importance of intercampus involvement in reporting of gainful employment student-level data that will be used in the calculation of gainful employment metrics by the U.S. Department of Education. The authors will discuss why building relationships within the institution is critical for effective gainful employment…

  3. Brand metrics that matter

    NARCIS (Netherlands)

    Muntinga, D.; Bernritter, S.

    2017-01-01

    Het merk staat steeds meer centraal in de organisatie. Het is daarom essentieel om de gezondheid, prestaties en ontwikkelingen van het merk te meten. Het is echter een uitdaging om de juiste brand metrics te selecteren. Een enorme hoeveelheid metrics vraagt de aandacht van merkbeheerders. Maar welke

  4. Privacy Metrics and Boundaries

    NARCIS (Netherlands)

    L-F. Pau (Louis-François)

    2005-01-01

    textabstractThis paper aims at defining a set of privacy metrics (quantitative and qualitative) in the case of the relation between a privacy protector ,and an information gatherer .The aims with such metrics are: -to allow to assess and compare different user scenarios and their differences; for

  5. Modeling of Body Weight Metrics for Effective and Cost-Efficient Conventional Factor VIII Dosing in Hemophilia A Prophylaxis

    Directory of Open Access Journals (Sweden)

    Alanna McEneny-King

    2017-10-01

    Full Text Available The total body weight-based dosing strategy currently used in the prophylactic treatment of hemophilia A may not be appropriate for all populations. The assumptions that guide weight-based dosing are not valid in overweight and obese populations, resulting in overdosing and ineffective resource utilization. We explored different weight metrics including lean body weight, ideal body weight, and adjusted body weight to determine an alternative dosing strategy that is both safe and resource-efficient in normal and overweight/obese adult patients. Using a validated population pharmacokinetic model, we simulated a variety of dosing regimens using different doses, weight metrics, and frequencies; we also investigated the implications of assuming various levels of endogenous factor production. Ideal body weight performed the best across all of the regimens explored, maintaining safety while moderating resource consumption for overweight and obese patients.

  6. Mapping resistance to powdery mildew in barley reveals a large-effect nonhost resistance QTL.

    Science.gov (United States)

    Romero, Cynara C T; Vermeulen, Jasper P; Vels, Anton; Himmelbach, Axel; Mascher, Martin; Niks, Rients E

    2018-05-01

    Resistance factors against non-adapted powdery mildews were mapped in barley. Some QTLs seem effective only to non-adapted mildews, while others also play a role in defense against the adapted form. The durability and effectiveness of nonhost resistance suggests promising practical applications for crop breeding, relying upon elucidation of key aspects of this type of resistance. We investigated which genetic factors determine the nonhost status of barley (Hordeum vulgare L.) to powdery mildews (Blumeria graminis). We set out to verify whether genes involved in nonhost resistance have a wide effectiveness spectrum, and whether nonhost resistance genes confer resistance to the barley adapted powdery mildew. Two barley lines, SusBgt SC and SusBgt DC , with some susceptibility to the wheat powdery mildew B. graminis f.sp. tritici (Bgt) were crossed with cv Vada to generate two mapping populations. Each population was assessed for level of infection against four B. graminis ff.spp, and QTL mapping analyses were performed. Our results demonstrate polygenic inheritance for nonhost resistance, with some QTLs effective only to non-adapted mildews, while others play a role against adapted and non-adapted forms. Histology analyses of nonhost interaction show that most penetration attempts are stopped in association with papillae, and also suggest independent layers of defence at haustorium establishment and conidiophore formation. Nonhost resistance of barley to powdery mildew relies mostly on non-hypersensitive mechanisms. A large-effect nonhost resistance QTL mapped to a 1.4 cM interval is suitable for map-based cloning.

  7. Effect of physiological age on radiation resistance of some bacteria that are highly radiation resistant

    International Nuclear Information System (INIS)

    Keller, L.C.; Maxcy, R.B.

    1984-01-01

    Physiological age-dependent variation in radiation resistance was studied for three bacteria that are highly radiation resistant: Micrococcus radiodurans, Micrococcus sp. isolate C-3, and Moraxella sp. isolate 4. Stationary-phase cultures of M. radiodurans and isolate C-3 were much more resistant to gamma radiation than were log-phase cultures. This pattern of relative resistance was reversed for isolate 4. Resistance of isolate 4 to UV light was also greater during log phase, although heat resistance and NaCl tolerance after heat stresses were greater during stationary phase. Radiation-induced injury of isolate 4 compared with injury of Escherichia coli B suggested that the injury process, as well as the lethal process, was affected by growth phase. The hypothesis that growth rate affects radiation resistance was tested, and results were interpreted in light of the probable confounding effect of methods used to alter growth rates of bacteria. These results indicate that dose-response experiments should be designed to measure survival during the most resistant growth phase of the organism under study. The timing is particularly important when extrapolations of survival results might be made to potential irradiation processes for foods. 17 references

  8. Enhancing Authentication Models Characteristic Metrics via ...

    African Journals Online (AJOL)

    In this work, we derive the universal characteristic metrics set for authentication models based on security, usability and design issues. We then compute the probability of the occurrence of each characteristic metrics in some single factor and multifactor authentication models in order to determine the effectiveness of these ...

  9. Insecticide Resistance Reducing Effectiveness of Malaria Control

    Centers for Disease Control (CDC) Podcasts

    2007-01-24

    Malaria prevention is increasingly insecticide based. Dr. John Gimnig, an entomologist with the Division of Parasitic Diseases, CDC, discusses evidence that mosquito resistance to insecticides, which is measured in the laboratory, could compromise malaria prevention in the field.  Created: 1/24/2007 by Emerging Infectious Diseases.   Date Released: 3/13/2007.

  10. Holographic Spherically Symmetric Metrics

    Science.gov (United States)

    Petri, Michael

    The holographic principle (HP) conjectures, that the maximum number of degrees of freedom of any realistic physical system is proportional to the system's boundary area. The HP has its roots in the study of black holes. It has recently been applied to cosmological solutions. In this article we apply the HP to spherically symmetric static space-times. We find that any regular spherically symmetric object saturating the HP is subject to tight constraints on the (interior) metric, energy-density, temperature and entropy-density. Whenever gravity can be described by a metric theory, gravity is macroscopically scale invariant and the laws of thermodynamics hold locally and globally, the (interior) metric of a regular holographic object is uniquely determined up to a constant factor and the interior matter-state must follow well defined scaling relations. When the metric theory of gravity is general relativity, the interior matter has an overall string equation of state (EOS) and a unique total energy-density. Thus the holographic metric derived in this article can serve as simple interior 4D realization of Mathur's string fuzzball proposal. Some properties of the holographic metric and its possible experimental verification are discussed. The geodesics of the holographic metric describe an isotropically expanding (or contracting) universe with a nearly homogeneous matter-distribution within the local Hubble volume. Due to the overall string EOS the active gravitational mass-density is zero, resulting in a coasting expansion with Ht = 1, which is compatible with the recent GRB-data.

  11. SU-E-I-28: Introduction and Investigation of Effective Diameter Ratios as a New Patient Size Metric for Use in CT

    Energy Technology Data Exchange (ETDEWEB)

    Lamoureux, R [Gainesville, FL (United States); Sinclair, L [Portland, OR (United States); Mench, A [Salem Health, Tualatin, OR (United States); Lipnharski, I; Carranza, C; Bidari, S [University of Florida, Gainesville, FL (United States); Cormack, B [UF Health, Gainesville, FL (United States); Rill, L [Univ Florida, Jacksonville Beach, FL (United States); Arreola, M [University of Florida Health Science Center, Gainesville, FL (United States)

    2015-06-15

    Purpose: To introduce and investigate effective diameter ratios as a new patient metric for use in computed tomography protocol selection as a supplement to patient-specific size parameter data. Methods: The metrics of outer effective diameter and inner effective diameter were measured for 7 post-mortem subjects scanned with a standardized chest/abdomen/pelvis (CAP) protocol on a 320-slice MDCT scanner. The outer effective diameter was calculated by obtaining the anterior/posterior and lateral dimensions of the imaged anatomy at the middle of the scan range using Effective Diameter= SQRT(AP height*Lat Width). The inner effective diameter was calculated with the same equation using the AP and Lat dimensions of the anatomy excluding the adipose tissue. The ratio of outer to inner effective diameter was calculated for each subject. A relationship to BMI, weight, and CTDI conversion coefficients was investigated. Results: For the largest subject with BMI of 43.85 kg/m2 and weight of 255 lbs the diameter ratio was calculated as 1.33. For the second largest subject with BMI of 33.5 kg/m2 and weight of 192.4 lbs the diameter ratio was measured as 1.43, indicating a larger percentage of adipose tissue in the second largest subject’s anatomical composition. For the smallest subject at BMI of 17.4 kg/m2 and weight of 86 lbs a similar tissue composition was indicated as a subject with BMI of 24.2 kg/m2 and weight of 136 lbs as they had the same diameter ratios of 1.11. Conclusion: The diameter ratio proves to contain information about anatomical composition that the BMI and weight alone do not. The utility of this metric is still being examined but could prove useful for determining MDCT techniques and for giving a more in depth detail of the composition of a patient’s body habitus.

  12. Effect of resistance and aerobic exercises on bone mineral density ...

    African Journals Online (AJOL)

    Conclusion: Based on obtained data, it can be concluded that, resistance and aerobic exercise training program is effective in increasing BMD, muscle strength and functional ability in children with hemophilia. Keywords: Hemophilia; Resistance; Aerobic exercise; Bone mineral density; Strength; Functional ability ...

  13. Anomaly effects of arrays for 3d geoelectrical resistivity imaging ...

    African Journals Online (AJOL)

    user

    The effectiveness of using a net of orthogonal or parallel sets of two-dimensional (2D) profiles for three- dimensional (3D) geoelectrical resistivity imaging has been evaluated. A series of 2D apparent resistivity data were generated over two synthetic models which represent geological or environmental conditions for a ...

  14. Effect of electrode shape on grounding resistances - Part 2

    DEFF Research Database (Denmark)

    Tomaskovicova, Sonia; Ingeman-Nielsen, Thomas; Christiansen, Anders V.

    2016-01-01

    Although electric resistivity tomography (ERT) is now regarded as a standard tool in permafrost monitoring, high grounding resistances continue to limit the acquisition of time series over complete freeze-thaw cycles. In an attempt to alleviate the grounding resistance problem, we have tested three...... electrode designs featuring increasing sizes and surface area, in the laboratory and at three different field sites in Greenland. Grounding resistance measurements showed that changing the electrode shape (using plates instead of rods) reduced the grounding resistances at all sites by 28%-69% during...... unfrozen and frozen ground conditions. Using meshes instead of plates (the same rectangular shape and a larger effective surface area) further improved the grounding resistances by 29%-37% in winter. Replacement of rod electrodes of one entire permanent permafrost monitoring array by meshes resulted...

  15. Effect of barnacle fouling on ship resistance and powering.

    Science.gov (United States)

    Demirel, Yigit Kemal; Uzun, Dogancan; Zhang, Yansheng; Fang, Ho-Chun; Day, Alexander H; Turan, Osman

    2017-11-01

    Predictions of added resistance and the effective power of ships were made for varying barnacle fouling conditions. A series of towing tests was carried out using flat plates covered with artificial barnacles. The tests were designed to allow the examination of the effects of barnacle height and percentage coverage on the resistance and effective power of ships. The drag coefficients and roughness function values were evaluated for the flat plates. The roughness effects of the fouling conditions on the ships' frictional resistances were predicted. Added resistance diagrams were then plotted using these predictions, and powering penalties for these ships were calculated using the diagrams generated. The results indicate that the effect of barnacle size is significant, since a 10% coverage of barnacles each 5 mm in height caused a similar level of added power requirements to a 50% coverage of barnacles each 1.25 mm in height.

  16. Pleiotropic Effects of DDT Resistance on Male Size and Behaviour.

    Science.gov (United States)

    Rostant, Wayne G; Bowyer, Jemima; Coupland, Jack; Facey, James; Hosken, David J; Wedell, Nina

    2017-07-01

    Understanding the evolution and spread of insecticide resistance requires knowing the relative fitness of resistant organisms. In the absence of insecticides, resistance is predicted to be costly. The Drosophila melanogaster DDT resistance allele (DDT-R) is associated with a male mating cost. This could be because resistant males are generally smaller, but DDT-R may also alter courtship behaviours. Here we tested for body size and courtship effects of DDT-R on mating success in competitive and non-competitive mating trials respectively. We also assessed relative aggression in resistant and susceptible males because aggression can also influence mating success. While the effect of DDT-R on male size partly contributed to reduced mating success, resistant males also had lower rates of courtship and were less aggressive than susceptible males. These differences contribute to the observed DDT-R mating costs. Additionally, these pleiotropic effects of DDT-R are consistent with the history and spread of resistance alleles in nature.

  17. Resistive effect on ion fishbone mode in tokamak plasma

    International Nuclear Information System (INIS)

    Shi Bingren; Vandam, J.W.; Carrera, R.; Zhang, Y.Z.

    1992-07-01

    A consistent theoretical description of the resistive internal mode is presented to discuss the effect of resistivity on fishbone mode for different parameter regime of bulk and hot components. It is found that the ideal fishbone mode theory ceases to be correct for the low frequency fishbone branch, the so-called ion fishbone mode, which has a real frequency very close to ω *i (the diamagnetic frequency) in marginal state. The stability domain analysis in β h , γ mhd ) space based on the resistive dispersion relation shows that the transition between the stable and unstable region is more complicated than predicted by the ideal limit theory. Another salient feature of the resistive fishbone mode is the existence of a weakly unstable regime. For high frequency fishbone with ω ∼ ω dm (the toroidal precession frequency of the hot ions) resistivity has negligible effect and the ideal theory is correct

  18. Probabilistic metric spaces

    CERN Document Server

    Schweizer, B

    2005-01-01

    Topics include special classes of probabilistic metric spaces, topologies, and several related structures, such as probabilistic normed and inner-product spaces. 1983 edition, updated with 3 new appendixes. Includes 17 illustrations.

  19. Tracker Performance Metric

    National Research Council Canada - National Science Library

    Olson, Teresa; Lee, Harry; Sanders, Johnnie

    2002-01-01

    .... We have developed the Tracker Performance Metric (TPM) specifically for this purpose. It was designed to measure the output performance, on a frame-by-frame basis, using its output position and quality...

  20. IT Project Management Metrics

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available Many software and IT projects fail in completing theirs objectives because different causes of which the management of the projects has a high weight. In order to have successfully projects, lessons learned have to be used, historical data to be collected and metrics and indicators have to be computed and used to compare them with past projects and avoid failure to happen. This paper presents some metrics that can be used for the IT project management.

  1. Mass Customization Measurements Metrics

    DEFF Research Database (Denmark)

    Nielsen, Kjeld; Brunø, Thomas Ditlev; Jørgensen, Kaj Asbjørn

    2014-01-01

    A recent survey has indicated that 17 % of companies have ceased mass customizing less than 1 year after initiating the effort. This paper presents measurement for a company’s mass customization performance, utilizing metrics within the three fundamental capabilities: robust process design, choice...... navigation, and solution space development. A mass customizer when assessing performance with these metrics can identify within which areas improvement would increase competitiveness the most and enable more efficient transition to mass customization....

  2. Effects of plant morphology on vegetation resistance, resilience and ...

    African Journals Online (AJOL)

    Effects of plant morphology on vegetation resistance, resilience and tolerance in. Mabira forest ... impacts of visitors activities of the camping sites and to understand the .... (Howard, 199 1 ): Milicia excels a, Cordia millenii, Irving/a gabonensis ...

  3. Effects of cost metric on cost-effectiveness of protected-area network design in urban landscapes.

    Science.gov (United States)

    Burkhalter, J C; Lockwood, J L; Maslo, B; Fenn, K H; Leu, K

    2016-04-01

    A common goal in conservation planning is to acquire areas that are critical to realizing biodiversity goals in the most cost-effective manner. The way monetary acquisition costs are represented in such planning is an understudied but vital component to realizing cost efficiencies. We sought to design a protected-area network within a forested urban region that would protect 17 birds of conservation concern. We compared the total costs and spatial structure of the optimal protected-area networks produced using three acquisition-cost surrogates (area, agricultural land value, and tax-assessed land value). Using the tax-assessed land values there was a 73% and 78% cost savings relative to networks derived using area or agricultural land value, respectively. This cost reduction was due to the considerable heterogeneity in acquisition costs revealed in tax-assessed land values, especially for small land parcels, and the corresponding ability of the optimization algorithm to identify lower-cost parcels for inclusion that had equal value to our target species. Tax-assessed land values also reflected the strong spatial differences in acquisition costs (US$0.33/m(2)-$55/m(2)) and thus allowed the algorithm to avoid inclusion of high-cost parcels when possible. Our results add to a nascent but growing literature that suggests conservation planners must consider the cost surrogate they use when designing protected-area networks. We suggest that choosing cost surrogates that capture spatial- and size-dependent heterogeneity in acquisition costs may be relevant to establishing protected areas in urbanizing ecosystems. © 2015 Society for Conservation Biology.

  4. Characterising risk - aggregated metrics: radiation and noise

    International Nuclear Information System (INIS)

    Passchier, W.

    1998-01-01

    The characterisation of risk is an important phase in the risk assessment - risk management process. From the multitude of risk attributes a few have to be selected to obtain a risk characteristic or profile that is useful for risk management decisions and implementation of protective measures. One way to reduce the number of attributes is aggregation. In the field of radiation protection such an aggregated metric is firmly established: effective dose. For protection against environmental noise the Health Council of the Netherlands recently proposed a set of aggregated metrics for noise annoyance and sleep disturbance. The presentation will discuss similarities and differences between these two metrics and practical limitations. The effective dose has proven its usefulness in designing radiation protection measures, which are related to the level of risk associated with the radiation practice in question, given that implicit judgements on radiation induced health effects are accepted. However, as the metric does not take into account the nature of radiation practice, it is less useful in policy discussions on the benefits and harm of radiation practices. With respect to the noise exposure metric, only one effect is targeted (annoyance), and the differences between sources are explicitly taken into account. This should make the metric useful in policy discussions with respect to physical planning and siting problems. The metric proposed has only significance on a population level, and can not be used as a predictor for individual risk. (author)

  5. Effects of aging and resistance training in rat tendon remodeling.

    Science.gov (United States)

    Marqueti, Rita C; Durigan, João L Q; Oliveira, Anderson José S; Mekaro, Marcelo Shinyu; Guzzoni, Vinicius; Aro, Andrea A; Pimentel, Edson Rosa; Selistre-de-Araujo, Heloisa S

    2018-01-01

    In elderly persons, weak tendons contribute to functional limitations, injuries, and disability, but resistance training can attenuate this age-related decline. We evaluated the effects of resistance training on the extracellular matrix (ECM) of the calcaneal tendon (CT) in young and old rats and its effect on tendon remodeling. Wistar rats aged 3 mo (young, n = 30) and 20 mo (old, n = 30) were divided into 4 groups: young sedentary, young trained, old sedentary (OS), and old trained (OT). The training sessions were conducted over a 12-wk period. Aging in sedentary rats showed down-regulation in key genes that regulated ECM remodeling. Moreover, the OS group showed a calcification focus in the distal region of the CT, with reduced blood vessel volume density. In contrast, resistance training was effective in up-regulating connective tissue growth factor, VEGF, and decorin gene expression in old rats. Resistance training also increased proteoglycan content in young and old rats in special small leucine-rich proteoglycans and blood vessels and prevented calcification in OT rats. These findings confirm that resistance training is a potential mechanism in the prevention of aging-related loss in ECM and that it attenuates the detrimental effects of aging in tendons, such as ruptures and tendinopathies.-Marqueti, R. C., Durigan, J. L. Q., Oliveira, A. J. S., Mekaro, M. S., Guzzoni, V., Aro, A. A., Pimentel, E. R., Selistre-de-Araujo, H. S. Effects of aging and resistance training in rat tendon remodeling. © FASEB.

  6. Elastic Resistance Effectiveness on Increasing Strength of Shoulders and Hips.

    Science.gov (United States)

    Picha, Kelsey J; Almaddah, Muataz R; Barker, Jordan; Ciochetty, Tavis; Black, W Scott; Uhl, Tim L

    2017-09-12

    Elastic resistance is a common training method used to gain strength. Currently, progression with elastic resistance is based on the perceived exertion of the exercise or completion of targeted repetitions; exact resistance is typically unknown. This study's objective is to determine if knowledge of load during elastic resistance exercise will increase strength gains during exercises. Participants were randomized into two strength training groups, elastic resistance only and elastic resistance using a load cell (LC) that displays force during exercise. The LC group used a Smart Handle (Patterson Medical Supply, Chicago, IL) to complete all exercises. Each participant completed the same exercises three times weekly for 8 weeks. The LC group was provided with a set load for exercises whereas the elastic resistance only group was not. Participant's strength was tested at baseline and program completion, measuring isometric strength for shoulder abduction (SAb), shoulder external rotation (SER), hip abduction (HAb), and hip extension (HEx). Independent t-tests were used to compare the normalized torques between groups. No significant differences were found between groups. Shoulder strength gains did not differ between groups (SAb p>0.05; SER p>0.05). Hip strength gains did not differ between groups (HAb p>0.05; HEx p>0.05). Both groups increased strength due to individual supervision, constantly evaluating degree of difficulty associated with exercise and providing feedback while using elastic resistance. Using a LC is as effective as supervised training and could provide value in a clinic setting when patients are working unsupervised.

  7. Effects of an Intensive Resistant Training Sessions and Green Tea

    Directory of Open Access Journals (Sweden)

    Mohammad Esmaeil Afzalpour

    2014-03-01

    Full Text Available Background: Intensive and acute exercise trainings may induce oxidative stress, but antioxidant supplements may attenuate its degenerative consequences. The aim of this research was to examine the effect of green tea supplementation on the oxidative stress indices after an intensive resistance training session. Materials and Methods: 40 non-athletes (without regular physical activity women were randomly divided into 4 equal (n=10 groups including green tea supplementation, green tea supplementation plus resistance training, resistance training, and control groups. After supplementation period (600 mg/day, 14 days, resistance training and green tea supplementation plus resistance training groups performed an intensive resistance training session at 75-85 % of one repetition maximum. The malondialdehyde and total thiol were measured as oxidative stress indices. Data were analyzed by using of repeated measure ANOVA and LSD tests at p<0.056T. Results: Results showed that after 14 days of green tea consumption, malondialdehyde significantly decreased in green tea supplementation (p=0.03 and green tea supplementation plus resistance training (p=0.01 groups, while total thiol increased significantly (p=0.01 in two green tea supplementation groups. However, an intensive resistance training session increased malondialdehyde (p=0.01 without any significantly changes in total thiol (p=0.426T. Conclusion: It seems that green tea supplementation can inhibit exercise-induced protein and lipid oxidation in non-athletes women via enhancement of antioxidant defense system of the body6T.6T

  8. Indefinite metric fields and the renormalization group

    International Nuclear Information System (INIS)

    Sherry, T.N.

    1976-11-01

    The renormalization group equations are derived for the Green functions of an indefinite metric field theory. In these equations one retains the mass dependence of the coefficient functions, since in the indefinite metric theories the masses cannot be neglected. The behavior of the effective coupling constant in the asymptotic and infrared limits is analyzed. The analysis is illustrated by means of a simple model incorporating indefinite metric fields. The model scales at first order, and at this order also the effective coupling constant has both ultra-violet and infra-red fixed points, the former being the bare coupling constant

  9. Chitosan as an effective inhibitor of multidrug resistant Acinetobacter baumannii.

    Science.gov (United States)

    Costa, E M; Silva, S; Vicente, S; Veiga, M; Tavaria, F; Pintado, M M

    2017-12-15

    Over the last two decades worldwide levels of antibiotic resistance have risen leading to the appearance of multidrug resistant microorganisms. Acinetobacter baumannii is a known skin pathogen which has emerged as a major cause of nosocomial outbreaks due to its capacity to colonize indwelling medical devices and natural antibiotic resistance. With chitosan being an effective antimicrobial agent against antibiotic resistant microorganisms, the aim of this work was to access its potential as an alternative to traditional antimicrobials in the management of A. baumannii growth. What the results showed was that both chitosan MW's tested were active upon A. baumannii's planktonic and sessile growth. For planktonic growth MICs and MBCs were obtained at relatively low concentrations (0.5-2mg/mL) while for sessile growth chitosan proved to be an effective inhibitor of A. baumannii's adhesion and biofilm formation. Considering these results chitosan shows a high potential for control of A. baumannii infections. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. Generalized two-dimensional (2D) linear system analysis metrics (GMTF, GDQE) for digital radiography systems including the effect of focal spot, magnification, scatter, and detector characteristics.

    Science.gov (United States)

    Jain, Amit; Kuhls-Gilcrist, Andrew T; Gupta, Sandesh K; Bednarek, Daniel R; Rudin, Stephen

    2010-03-01

    The MTF, NNPS, and DQE are standard linear system metrics used to characterize intrinsic detector performance. To evaluate total system performance for actual clinical conditions, generalized linear system metrics (GMTF, GNNPS and GDQE) that include the effect of the focal spot distribution, scattered radiation, and geometric unsharpness are more meaningful and appropriate. In this study, a two-dimensional (2D) generalized linear system analysis was carried out for a standard flat panel detector (FPD) (194-micron pixel pitch and 600-micron thick CsI) and a newly-developed, high-resolution, micro-angiographic fluoroscope (MAF) (35-micron pixel pitch and 300-micron thick CsI). Realistic clinical parameters and x-ray spectra were used. The 2D detector MTFs were calculated using the new Noise Response method and slanted edge method and 2D focal spot distribution measurements were done using a pin-hole assembly. The scatter fraction, generated for a uniform head equivalent phantom, was measured and the scatter MTF was simulated with a theoretical model. Different magnifications and scatter fractions were used to estimate the 2D GMTF, GNNPS and GDQE for both detectors. Results show spatial non-isotropy for the 2D generalized metrics which provide a quantitative description of the performance of the complete imaging system for both detectors. This generalized analysis demonstrated that the MAF and FPD have similar capabilities at lower spatial frequencies, but that the MAF has superior performance over the FPD at higher frequencies even when considering focal spot blurring and scatter. This 2D generalized performance analysis is a valuable tool to evaluate total system capabilities and to enable optimized design for specific imaging tasks.

  11. Adaptive metric kernel regression

    DEFF Research Database (Denmark)

    Goutte, Cyril; Larsen, Jan

    2000-01-01

    Kernel smoothing is a widely used non-parametric pattern recognition technique. By nature, it suffers from the curse of dimensionality and is usually difficult to apply to high input dimensions. In this contribution, we propose an algorithm that adapts the input metric used in multivariate...... regression by minimising a cross-validation estimate of the generalisation error. This allows to automatically adjust the importance of different dimensions. The improvement in terms of modelling performance is illustrated on a variable selection task where the adaptive metric kernel clearly outperforms...

  12. Adaptive Metric Kernel Regression

    DEFF Research Database (Denmark)

    Goutte, Cyril; Larsen, Jan

    1998-01-01

    Kernel smoothing is a widely used nonparametric pattern recognition technique. By nature, it suffers from the curse of dimensionality and is usually difficult to apply to high input dimensions. In this paper, we propose an algorithm that adapts the input metric used in multivariate regression...... by minimising a cross-validation estimate of the generalisation error. This allows one to automatically adjust the importance of different dimensions. The improvement in terms of modelling performance is illustrated on a variable selection task where the adaptive metric kernel clearly outperforms the standard...

  13. A filled duration illusion in music: Effects of metrical subdivision on the perception and production of beat tempo.

    Science.gov (United States)

    Repp, Bruno H; Bruttomesso, Meijin

    2010-01-13

    This study replicates and extends previous findings suggesting that metrical subdivision slows the perceived beat tempo (Repp, 2008). Here, musically trained participants produced the subdivisions themselves and were found to speed up, thus compensating for the perceived slowing. This was shown in a synchronization-continuation paradigm (Experiment 1) and in a reproduction task (Experiment 2a). Participants also judged the tempo of a subdivided sequence as being slower than that of a preceding simple beat sequence (Experiment 2b). Experiment 2 also included nonmusician participants, with similar results. Tempo measurements of famous pianists' recordings of two variation movements from Beethoven sonatas revealed a strong tendency to play the first variation (subdivided beats) faster than the theme (mostly simple beats). A similar tendency was found in musicians' laboratory performances of a simple theme and variations, despite instruc-tions to keep the tempo constant (Experiment 3a). When playing melodic sequences in which only one of three beats per measure was subdivided, musicians tended to play these beats faster and to perceive them as longer than adjacent beats, and they played the whole sequence faster than a sequence without any subdivisions (Experiments 3b and 3c). The results amply demonstrate a filled duration illusion in rhythm perception and music performance: Intervals containing events seem longer than empty intervals and thus must be shortened to be perceived as equal in duration.

  14. Origins of effective resistivity in collisionless magnetic reconnection

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Nagendra [Electrical and Computer Engineering, University of Alabama, Huntsville, Alabama 35899 (United States)

    2014-07-15

    The mechanisms that provide effective resistivity for supporting collisonless magnetic reconnection have remained unsettled despite numerous studies. Some of these studies demonstrated that the electron pressure nongyrotropy generates the resistivity (η{sub npg}) in the electron diffusion region (EDR). We derive an analytical relation for the effective resistivity (η{sub kin}) by momentum balance in a control volume in the EDR. Both η{sub npg} and η{sub kin} mutually compare well and they also compare well with the resistivity required to support reconnection electric field E{sub rec} in multi-dimensional particle-in-cell simulations as well as in satellite observations when reconnection occurs in an EDR. But they are about an order of magnitude or so smaller than that required when the reconnection occurred in a much wider reconnecting current sheet (RCS) of half width (w) of the order of the ion skin depth (d{sub i}), observed in the Earth magnetosphere. The chaos-induced resistivity reported in the literature is found to be even more deficient. We find that for reconnection in RCS with w ∼ d{sub i}, anomalous diffusion, such as the universal Bhom diffusion and/or that arising from kinetic Alfven waves, could fairly well account for the required resistivity.

  15. Effect of radiation resistance additives for insulation materials

    International Nuclear Information System (INIS)

    Yamamoto, Yasuaki; Yagyu, Hideki; Seguchi, Tadao.

    1988-01-01

    For the electric wires and cables used in radiation environment such as nuclear power stations and fuel reprocessing facilities, the properties of excellent radiation resistance are required. For these insulators and sheath materials, ethylene propylene rubber, polyethylene and other polymers have been used, but it cannot be said that they always have good radiation resistance. However, it has been well known that radiation resistance can be improved with small amount of additives, and heat resistance and burning retarding property as well as radiation resistance are given to the insulators of wires and cables for nuclear facilities by mixing various additives. In this research, the measuring method for quantitatively determining the effect of Anti-rad (radiation resistant additive) was examined. Through the measurement of gel fraction, radical formation and decomposed gas generation, the effect of Anti-rad protecting polymers from radiation deterioration was examined from the viewpoint of chemical reaction. The experimental method and the results are reported. The radiation energy for cutting C-H coupling is polymers is dispersed by Anti-rad, and the probability of cutting is lowered. Anti-rad catches and extinguishes radicals that start oxidation reaction. (K.I.)

  16. Metrical Phonology and SLA.

    Science.gov (United States)

    Tice, Bradley S.

    Metrical phonology, a linguistic process of phonological stress assessment and diagrammatic simplification of sentence and word stress, is discussed as it is found in the English language with the intention that it may be used in second language instruction. Stress is defined by its physical and acoustical correlates, and the principles of…

  17. Metrics for Probabilistic Geometries

    DEFF Research Database (Denmark)

    Tosi, Alessandra; Hauberg, Søren; Vellido, Alfredo

    2014-01-01

    the distribution over mappings is given by a Gaussian process. We treat the corresponding latent variable model as a Riemannian manifold and we use the expectation of the metric under the Gaussian process prior to define interpolating paths and measure distance between latent points. We show how distances...

  18. Analyzing the effects of urban expansion on land surface temperature patterns by landscape metrics: a case study of Isfahan city, Iran.

    Science.gov (United States)

    Madanian, Maliheh; Soffianian, Ali Reza; Koupai, Saeid Soltani; Pourmanafi, Saeid; Momeni, Mehdi

    2018-03-03

    Urban expansion can cause extensive changes in land use and land cover (LULC), leading to changes in temperature conditions. Land surface temperature (LST) is one of the key parameters that should be considered in the study of urban temperature conditions. The purpose of this study was, therefore, to investigate the effects of changes in LULC due to the expansion of the city of Isfahan on LST using landscape metrics. To this aim, two Landsat 5 and Landsat 8 images, which had been acquired, respectively, on August 2, 1985, and July 4, 2015, were used. The support vector machine method was then used to classify the images. The results showed that Isfahan city had been encountered with an increase of impervious surfaces; in fact, this class covered 15% of the total area in 1985, while this value had been increased to 30% in 2015. Then LST zoning maps were created, indicating that the bare land and impervious surfaces categories were dominant in high temperature zones, while in the zones where water was present or NDVI was high, LST was low. Then, the landscape metrics in each of the LST zones were analyzed in relation to the LULC changes, showing that LULC changes due to urban expansion changed such landscape properties as the percentage of landscape, patch density, large patch index, and aggregation index. This information could be beneficial for urban planners to monitor and manage changes in the LULC patterns.

  19. Massless and massive quanta resulting from a mediumlike metric tensor

    International Nuclear Information System (INIS)

    Soln, J.

    1985-01-01

    A simple model of the ''primordial'' scalar field theory is presented in which the metric tensor is a generalization of the metric tensor from electrodynamics in a medium. The radiation signal corresponding to the scalar field propagates with a velocity that is generally less than c. This signal can be associated simultaneously with imaginary and real effective (momentum-dependent) masses. The requirement that the imaginary effective mass vanishes, which we take to be the prerequisite for the vacuumlike signal propagation, leads to the ''spontaneous'' splitting of the metric tensor into two distinct metric tensors: one metric tensor gives rise to masslesslike radiation and the other to a massive particle. (author)

  20. Metrics for energy resilience

    International Nuclear Information System (INIS)

    Roege, Paul E.; Collier, Zachary A.; Mancillas, James; McDonagh, John A.; Linkov, Igor

    2014-01-01

    Energy lies at the backbone of any advanced society and constitutes an essential prerequisite for economic growth, social order and national defense. However there is an Achilles heel to today's energy and technology relationship; namely a precarious intimacy between energy and the fiscal, social, and technical systems it supports. Recently, widespread and persistent disruptions in energy systems have highlighted the extent of this dependence and the vulnerability of increasingly optimized systems to changing conditions. Resilience is an emerging concept that offers to reconcile considerations of performance under dynamic environments and across multiple time frames by supplementing traditionally static system performance measures to consider behaviors under changing conditions and complex interactions among physical, information and human domains. This paper identifies metrics useful to implement guidance for energy-related planning, design, investment, and operation. Recommendations are presented using a matrix format to provide a structured and comprehensive framework of metrics relevant to a system's energy resilience. The study synthesizes previously proposed metrics and emergent resilience literature to provide a multi-dimensional model intended for use by leaders and practitioners as they transform our energy posture from one of stasis and reaction to one that is proactive and which fosters sustainable growth. - Highlights: • Resilience is the ability of a system to recover from adversity. • There is a need for methods to quantify and measure system resilience. • We developed a matrix-based approach to generate energy resilience metrics. • These metrics can be used in energy planning, system design, and operations

  1. Effect of Air Gap Entrapped in Firefighter Protective Clothing on Thermal Resistance and Evaporative Resistance

    Directory of Open Access Journals (Sweden)

    He Hualing

    2018-03-01

    Full Text Available Heat and water vapor transfer behavior of thermal protective clothing is greatly influenced by the air gap entrapped in multilayer fabric system. In this study, a sweating hot plate method was used to investigate the effect of air gap position and size on thermal resistance and evaporative resistance of firefighter clothing under a range of ambient temperature and humidity. Results indicated that the presence of air gap in multilayer fabric system decreased heat and water vapor transfer abilities under normal wear. Moreover, the air gap position slightly influenced the thermal and evaporative performances of the firefighter clothing. In this study, the multilayer fabric system obtained the highest thermal resistance, when the air space was located at position B. Furthermore, the effect of ambient temperature on heat and water vapor transfer properties of the multilayer fabric system was also investigated in the presence of a specific air gap. It was indicated that ambient temperature did not influence the evaporative resistance of thermal protective clothing. A thermographic image was used to test the surface temperature of multilayer fabric system when an air gap was incorporated. These results suggested that a certain air gap entrapped in thermal protective clothing system could affect wear comfort.

  2. Marketing communication metrics for social media

    OpenAIRE

    Töllinen, Aarne; Karjaluoto, Heikki

    2011-01-01

    The objective of this paper is to develop a conceptual framework for measuring the effectiveness of social media marketing communications. Specifically, we study whether the existing marketing communications performance metrics are still valid in the changing digitalised communications landscape, or whether it is time to rethink them, or even to devise entirely new metrics. Recent advances in information technology and marketing bring a need to re-examine measurement models. We combine two im...

  3. Effect of modes interaction on the resistive wall mode stability

    International Nuclear Information System (INIS)

    Chen Longxi; Wu Bin

    2013-01-01

    Effects of modes interaction on the resistive wall mode (RWM) stability are studied. When considering the modes interaction effects, the linear growth rate of the most unstable (3, 1) mode decreases. After linear evolution, the RWM saturates at the nonlinear phase. The saturation can be attributed to flux piling up on the resistive wall. When some modes exist, the (3, 1) mode saturates at lower level compared with single mode evolution. Meanwhile, the magnetic energy of the (5, 2) mode increases correspondingly, but the magnetic energy saturation level of the (2, 1) mode changes weakly. (authors)

  4. Effects of prestressing on impact resistance of concrete beams

    International Nuclear Information System (INIS)

    Mikami, H.; Kishi, N.; Matsuoka, K.G.; Mikami, T.; Nomachi, S.G.

    1995-01-01

    In this paper, the effects of prestressing on impact resistance of concrete beams using two types of prestressed concrete (PC) tendons are discussed based on experimental results. Aramids Fiber Reinforced Plastic rods and PC steel strand were used as PC tendons. To clarify the effects of prestressing on concrete beam impact resistance, dynamic behavior of prestressed and/or non-prestressed concrete beams with different PC tendon arrangements were considered. Impact test were performed using a 200 kg f free falling steel weight on to the center of beam. (author). 10 refs., 5 figs., 2 tabs

  5. Magnetic property effect on transport processes in resistance spot welding

    Energy Technology Data Exchange (ETDEWEB)

    Wei, P S [Department of Mechanical and Electro-Mechanical Engineering, National Sun Yat-Sen University, Kaohsiung, Taiwan 80424 (China); Wu, T H, E-mail: pswei@mail.nsysu.edu.tw, E-mail: wux0064@gmail.com [Department of Mechanical Engineering, Yung Ta Institute of Technology and Commerce, Pintong, Taiwan 909 (China)

    2011-08-17

    This study investigates the effects of the Curie temperature and magnetic permeability on transport variables, solute distribution and nugget shapes during resistance spot welding. The Curie temperature is the temperature below which a metal or alloy is ferromagnetic with a high magnetic permeability, and above which it is paramagnetic with a small magnetic permeability. The model proposed here accounts for electromagnetic force, heat generation and contact resistance at the faying surface and electrode-workpiece interfaces and bulk resistance in workpieces. Contact resistance includes constriction and film resistances, which are functions of hardness, temperature, electrode force and surface condition. The computed results show that transport variables and nugget shapes can be consistently interpreted from the delay of response time and jump of electric current density as a result of finite magnetic diffusion, rather than through the examination of the variations of dynamic electrical resistance with time. The molten nugget on the faying surface is initiated earlier with increasing magnetic permeability and Curie temperature. A high Curie temperature enhances convection and solute mixing, and readily melts through the workpiece surface near the electrode edge. Any means to reduce the Curie temperature or magnetic permeability, such as adjusting the solute content, can be a good way to control weld quality. This study can also be applied to interpret the contact problems encountered in various electronics and packaging technologies, and so on.

  6. Hybrid metric-Palatini stars

    Science.gov (United States)

    Danilǎ, Bogdan; Harko, Tiberiu; Lobo, Francisco S. N.; Mak, M. K.

    2017-02-01

    We consider the internal structure and the physical properties of specific classes of neutron, quark and Bose-Einstein condensate stars in the recently proposed hybrid metric-Palatini gravity theory, which is a combination of the metric and Palatini f (R ) formalisms. It turns out that the theory is very successful in accounting for the observed phenomenology, since it unifies local constraints at the Solar System level and the late-time cosmic acceleration, even if the scalar field is very light. In this paper, we derive the equilibrium equations for a spherically symmetric configuration (mass continuity and Tolman-Oppenheimer-Volkoff) in the framework of the scalar-tensor representation of the hybrid metric-Palatini theory, and we investigate their solutions numerically for different equations of state of neutron and quark matter, by adopting for the scalar field potential a Higgs-type form. It turns out that the scalar-tensor definition of the potential can be represented as an Clairaut differential equation, and provides an explicit form for f (R ) given by f (R )˜R +Λeff, where Λeff is an effective cosmological constant. Furthermore, stellar models, described by the stiff fluid, radiation-like, bag model and the Bose-Einstein condensate equations of state are explicitly constructed in both general relativity and hybrid metric-Palatini gravity, thus allowing an in-depth comparison between the predictions of these two gravitational theories. As a general result it turns out that for all the considered equations of state, hybrid gravity stars are more massive than their general relativistic counterparts. Furthermore, two classes of stellar models corresponding to two particular choices of the functional form of the scalar field (constant value, and logarithmic form, respectively) are also investigated. Interestingly enough, in the case of a constant scalar field the equation of state of the matter takes the form of the bag model equation of state describing

  7. The effects of endurance and resistance training on blood pressure.

    Science.gov (United States)

    Schwartz, R S; Hirth, V A

    1995-10-01

    There now exists substantial clinical data supporting a blood pressure lowering effect of endurance training. Though the effect is modest (5-10 mmHg), epidemiologic studies indicate the possibility of protection against the development of hypertension and also indicate significantly reduced cardiovascular mortality and increased longevity associated with chronic endurance exercise. The data for blood pressure lowering effects of resistive training are much less compelling, and this area requires additional investigation. However, it appears that resistance training is not associated with chronic elevations in blood pressure. Future studies need to focus on: 1) the relative efficacy of low-, moderate- and high-intensity training on lowering blood pressure; 2) the effect of training on ambulatory blood pressure; 3) targeting of at risk and high responding populations; and 4) the importance of insulinemia, SNS tone and central adiposity in the mechanism of any blood pressure lowering effect of training.

  8. Enterprise Sustainment Metrics

    Science.gov (United States)

    2015-06-19

    are negatively impacting KPIs” (Parmenter, 2010: 31). In the current state, the Air Force’s AA and PBL metrics are once again split . AA does...must have the authority to “take immediate action to rectify situations that are negatively impacting KPIs” (Parmenter, 2010: 31). 3. Measuring...highest profitability and shareholder value for each company” (2014: 273). By systematically diagraming a process, either through a swim lane flowchart

  9. Effect of temperature on structure and corrosion resistance for ...

    Indian Academy of Sciences (India)

    The effect of plating temperatures between 60 and 90◦C on structure and corrosion resistance for elec- troless NiWP coatings ..... which helps to form fine grain. At 80 .... [23] Zhang W X, Jiang Z H, Li G Y and Jiang Q 2008 Surf. Coat. Technol.

  10. Effects of 16 weeks of aerobic, resistance and combination exercise ...

    African Journals Online (AJOL)

    Effects of 16 weeks of aerobic, resistance and combination exercise programmes on smoking. ... African Journal for Physical Activity and Health Sciences ... Abstract. Previous research on the cessation of smoking and the prevention of smoking recidivism using exercise training has mainly focused on aerobic training (AER).

  11. Symmetries of the dual metrics

    International Nuclear Information System (INIS)

    Baleanu, D.

    1998-01-01

    The geometric duality between the metric g μν and a Killing tensor K μν is studied. The conditions were found when the symmetries of the metric g μν and the dual metric K μν are the same. Dual spinning space was constructed without introduction of torsion. The general results are applied to the case of Kerr-Newmann metric

  12. Kerr metric in cosmological background

    Energy Technology Data Exchange (ETDEWEB)

    Vaidya, P C [Gujarat Univ., Ahmedabad (India). Dept. of Mathematics

    1977-06-01

    A metric satisfying Einstein's equation is given which in the vicinity of the source reduces to the well-known Kerr metric and which at large distances reduces to the Robertson-Walker metric of a nomogeneous cosmological model. The radius of the event horizon of the Kerr black hole in the cosmological background is found out.

  13. How to measure top-down vs. bottom-up effects: A new population metric and its calibration on Daphnia

    NARCIS (Netherlands)

    Polishchuk, L.; Vijverberg, J.; Voronov, D.A.; Mooij, W.M.

    2013-01-01

    Research on the role of top–down (predation) and bottom–up (food) effects in food webs has led to the understanding that the variability of these effects in space and time is a fundamental feature of natural systems. Consequently, our measurement tools must allow us to evaluate the effects from a

  14. Effect of Coffee and Caffeine Ingestion on Resistance Exercise Performance.

    Science.gov (United States)

    Richardson, Darren L; Clarke, Neil D

    2016-10-01

    Richardson, DL and Clarke, ND. Effect of coffee and caffeine ingestion on resistance exercise performance. J Strength Cond Res 30(10): 2892-2900, 2016-The aim of the present study was to determine the effect of ingesting caffeine dose-matched anhydrous caffeine, coffee, or decaffeinated coffee plus anhydrous caffeine during resistance exercise on performance. Nine resistance-trained men (mean ± SD: age, 24 ± 2 years; weight, 84 ± 8 kg; height, 180 ± 8 cm) completed a squat and bench press exercise protocol at 60% 1 repetition maximum until failure on 5 occasions consuming 0.15 g·kg caffeinated coffee (COF), 0.15 g·kg decaffeinated coffee (DEC), 0.15 g·kg decaffeinated coffee plus 5 mg·kg anhydrous caffeine (D + C), 5 mg·kg anhydrous caffeine (CAF), or a placebo (PLA). Felt arousal and rating of perceived exertion (RPE) were used to assess perceptual variables and heart rate (HR) to assess physiological responses between trials. There were significant differences in total weight lifted for the squat between conditions (p caffeine have the ability to improve performance during a resistance exercise protocol, although possibly not over multiple bouts.

  15. Learning Low-Dimensional Metrics

    OpenAIRE

    Jain, Lalit; Mason, Blake; Nowak, Robert

    2017-01-01

    This paper investigates the theoretical foundations of metric learning, focused on three key questions that are not fully addressed in prior work: 1) we consider learning general low-dimensional (low-rank) metrics as well as sparse metrics; 2) we develop upper and lower (minimax)bounds on the generalization error; 3) we quantify the sample complexity of metric learning in terms of the dimension of the feature space and the dimension/rank of the underlying metric;4) we also bound the accuracy ...

  16. Effect of cigarette smoking on insulin resistance risk.

    Science.gov (United States)

    Haj Mouhamed, D; Ezzaher, A; Neffati, F; Douki, W; Gaha, L; Najjar, M F

    2016-02-01

    Smoking is one of the main risk factors for cardiovascular disease (CVD). The mechanism(s) of the effects of smoking on CVD are not clearly understood; however, a number of atherogenic characteristics, such as insulin resistance have been reported. We aim to investigate the effects of cigarette smoking on insulin resistance and to determine the correlation between this parameter with smoking status characteristics. This study was conducted on 138 non-smokers and 162 smokers aged respectively 35.6±16.0 and 38.5±21.9 years. All subjects are not diabetic. Fasting glucose was determined by enzymatic methods and insulin by chemiluminescence method. Insulin resistance (IR) was estimated using the Homeostasis Model of Assessment equation: HOMA-IR=[fasting insulin (mU/L)×fasting glucose (mmol/L)]/22.5. IR was defined as the upper quartile of HOMA-IR. Values above 2.5 were taken as abnormal and reflect insulin resistance. Compared to non-smokers, smokers had significantly higher levels of fasting glucose, fasting insulin and HOMA-IR index. These associations remained significant after adjustment for confounding factors (age, gender, BMI and alcohol consumption). A statistically significant association was noted between the smoking status parameters, including both the number of cigarettes smoked/day and the duration of smoking, and fasting insulin levels as well for HOMA-IR index. Among smokers, we noted a positive correlation between HOMA-IR index and both plasma thiocyanates and urinary cotinine. Our results show that smokers have a high risk to developing an insulin resistance and hyperinsulinemia, compared with a matched group of non-smokers, and may help to explain the high risk of cardiovascular diseases in smokers. Copyright © 2015. Published by Elsevier SAS.

  17. The correlation of metrics in complex networks with applications in functional brain networks

    NARCIS (Netherlands)

    Li, C.; Wang, H.; De Haan, W.; Stam, C.J.; Van Mieghem, P.F.A.

    2011-01-01

    An increasing number of network metrics have been applied in network analysis. If metric relations were known better, we could more effectively characterize networks by a small set of metrics to discover the association between network properties/metrics and network functioning. In this paper, we

  18. Short Lived Climate Pollutants cause a Long Lived Effect on Sea-level Rise: Analyzing climate metrics for sea-level rise

    Science.gov (United States)

    Sterner, E.; Johansson, D. J.

    2013-12-01

    Climate change depends on the increase of several different atmospheric pollutants. While long term global warming will be determined mainly by carbon dioxide, warming in the next few decades will depend to a large extent on short lived climate pollutants (SLCP). Reducing emissions of SLCPs could contribute to lower the global mean surface temperature by 0.5 °C already by 2050 (Shindell et al. 2012). Furthermore, the warming effect of one of the most potent SLCPs, black carbon (BC), may have been underestimated in the past. Bond et al. (2013) presents a new best estimate of the total BC radiative forcing (RF) of 1.1 W/m2 (90 % uncertainty bounds of 0.17 to 2.1 W/m2) since the beginning of the industrial era. BC is however never emitted alone and cooling aerosols from the same sources offset a majority of this RF. In the wake of calls for mitigation of SLCPs it is important to study other aspects of the climate effect of SLCPs. One key impact of climate change is sea-level rise (SLR). In a recent study, the effect of SLCP mitigation scenarios on SLR is examined. Hu et al (2013) find a substantial effect on SLR from mitigating SLCPs sharply, reducing SLR by 22-42% by 2100. We choose a different approach focusing on emission pulses and analyse a metric based on sea level rise so as to further enlighten the SLR consequences of SLCPs. We want in particular to understand the time dynamics of SLR impacts caused by SLCPs compared to other greenhouse gases. The most commonly used physical based metrics are GWP and GTP. We propose and evaluate an additional metric: The global sea-level rise potential (GSP). The GSP is defined as the sea level rise after a time horizon caused by an emissions pulse of a forcer to the sea level rise after a time horizon caused by an emissions pulse of a CO2. GSP is evaluated and compared to GWP and GTP using a set of climate forcers chosen to cover the whole scale of atmospheric perturbation life times (BC, CH4, N2O, CO2 and SF6). The study

  19. Resistivity and Hall effect in Y9Co7

    International Nuclear Information System (INIS)

    Ali, N.; Datars, W.R.; Kozlowski, G.; Woods, S.B.

    1987-01-01

    The temperature dependence of the resistivity and Hall effect of Y 9 Co 7 has been measured from room temperature to 1.6 K. The saturation of the resistivity at high temperature is similar to that of A15 compounds and can be interpreted in terms of a localised phonon mode formation as shown by Yu and Anderson for A15 compounds. A T 2 -dependence of the resistivity is observed for temperatures below approx.= 25 K. A similar T 2 -dependence at low temperatures is always observed in A15 compounds as well and is not fully understood. However, a T 2 -dependence below 10 K does not seem to be due to itinerant ferromagnetism in Y 9 Co 7 as concluded recently by Kolodziejczyk and Spalek. The observation of a peak at approx.= 25 K in the Hall coefficient suggests a spin glass type of freezing at low temperatures which possibly can account for the T 2 -dependence of the resistivity below approx.= 10 K. (author)

  20. Effect Sizes for Growth-Modeling Analysis for Controlled Clinical Trials in the Same Metric as for Classical Analysis

    Science.gov (United States)

    Feingold, Alan

    2009-01-01

    The use of growth-modeling analysis (GMA)--including hierarchical linear models, latent growth models, and general estimating equations--to evaluate interventions in psychology, psychiatry, and prevention science has grown rapidly over the last decade. However, an effect size associated with the difference between the trajectories of the…

  1. Effectiveness analysis of resistance and tolerance to infection

    Directory of Open Access Journals (Sweden)

    Detilleux Johann C

    2011-03-01

    Full Text Available Abstract Background Tolerance and resistance provide animals with two distinct strategies to fight infectious pathogens and may exhibit different evolutionary dynamics. However, few studies have investigated these mechanisms in the case of animal diseases under commercial constraints. Methods The paper proposes a method to simultaneously describe (1 the dynamics of transmission of a contagious pathogen between animals, (2 the growth and death of the pathogen within infected hosts and (3 the effects on their performances. The effectiveness of increasing individual levels of tolerance and resistance is evaluated by the number of infected animals and the performance at the population level. Results The model is applied to a particular set of parameters and different combinations of values. Given these imputed values, it is shown that higher levels of individual tolerance should be more effective than increased levels of resistance in commercial populations. As a practical example, a method is proposed to measure levels of animal tolerance to bovine mastitis. Conclusions The model provides a general framework and some tools to maximize health and performances of a population under infection. Limits and assumptions of the model are clearly identified so it can be improved for different epidemiological settings.

  2. Effect and Safety of Shihogyejitang for Drug Resistant Childhood Epilepsy

    Directory of Open Access Journals (Sweden)

    Jinsoo Lee

    2016-01-01

    Full Text Available Objective. Herbal medicine has been widely used to treat drug resistant epilepsy. Shihogyejitang (SGT has been commonly used to treat epilepsy. We investigated the effect and safety of SGT in children with drug resistant epilepsy. Design. We reviewed medical records of 54 patients with epilepsy, who failed to respond to at least two antiepileptic drugs and have been treated with SGT between April 2006 and June 2014 at the Department of Pediatric Neurology, I-Tomato Hospital, Korea. Effect was measured by the response rate, seizure-free rate, and retention rate at six months. We also checked adverse events, change in antiepileptic drugs use, and the variables related to the outcome. Results. Intent-to-treat analysis showed that, after six months, 44.4% showed a >50% seizure reduction, 24.1% including seizure-free, respectively, and 53.7% remained on SGT. Two adverse events were reported, mild skin rash and fever. Focal seizure type presented significantly more positive responses when compared with other seizure types at six months (p=0.0284, Fisher’s exact test. Conclusion. SGT is an effective treatment with excellent tolerability for drug resistant epilepsy patients. Our data provide evidence that SGT may be used as alternative treatment option when antiepileptic drug does not work in epilepsy children.

  3. Metrics with vanishing quantum corrections

    International Nuclear Information System (INIS)

    Coley, A A; Hervik, S; Gibbons, G W; Pope, C N

    2008-01-01

    We investigate solutions of the classical Einstein or supergravity equations that solve any set of quantum corrected Einstein equations in which the Einstein tensor plus a multiple of the metric is equated to a symmetric conserved tensor T μν (g αβ , ∂ τ g αβ , ∂ τ ∂ σ g αβ , ...,) constructed from sums of terms, the involving contractions of the metric and powers of arbitrary covariant derivatives of the curvature tensor. A classical solution, such as an Einstein metric, is called universal if, when evaluated on that Einstein metric, T μν is a multiple of the metric. A Ricci flat classical solution is called strongly universal if, when evaluated on that Ricci flat metric, T μν vanishes. It is well known that pp-waves in four spacetime dimensions are strongly universal. We focus attention on a natural generalization; Einstein metrics with holonomy Sim(n - 2) in which all scalar invariants are zero or constant. In four dimensions we demonstrate that the generalized Ghanam-Thompson metric is weakly universal and that the Goldberg-Kerr metric is strongly universal; indeed, we show that universality extends to all four-dimensional Sim(2) Einstein metrics. We also discuss generalizations to higher dimensions

  4. Sharp metric obstructions for quasi-Einstein metrics

    Science.gov (United States)

    Case, Jeffrey S.

    2013-02-01

    Using the tractor calculus to study smooth metric measure spaces, we adapt results of Gover and Nurowski to give sharp metric obstructions to the existence of quasi-Einstein metrics on suitably generic manifolds. We do this by introducing an analogue of the Weyl tractor W to the setting of smooth metric measure spaces. The obstructions we obtain can be realized as tensorial invariants which are polynomial in the Riemann curvature tensor and its divergence. By taking suitable limits of their tensorial forms, we then find obstructions to the existence of static potentials, generalizing to higher dimensions a result of Bartnik and Tod, and to the existence of potentials for gradient Ricci solitons.

  5. Inactivation Effect of Antibiotic-Resistant Gene Using Chlorine Disinfection

    Directory of Open Access Journals (Sweden)

    Takashi Furukawa

    2017-07-01

    Full Text Available The aim of this study was to elucidate the inactivation effects on the antibiotic-resistance gene (vanA of vancomycin-resistant enterococci (VRE using chlorination, a disinfection method widely used in various water treatment facilities. Suspensions of VRE were prepared by adding VRE to phosphate-buffered saline, or the sterilized secondary effluent of a wastewater treatment plant. The inactivation experiments were carried out at several chlorine concentrations and stirring time. Enterococci concentration and presence of vanA were determined. The enterococci concentration decreased as chlorine concentrations and stirring times increased, with more than 7.0 log reduction occurring under the following conditions: 40 min stirring at 0.5 mg Cl2/L, 20 min stirring at 1.0 mg Cl2/L, and 3 min stirring at 3.0 mg Cl2/L. In the inactivation experiment using VRE suspended in secondary effluent, the culturable enterococci required much higher chlorine concentration and longer treatment time for complete disinfection than the cases of suspension of VRE. However, vanA was detected in all chlorinated suspensions of VRE, even in samples where no enterococcal colonies were present on the medium agar plate. The chlorine disinfection was not able to destroy antibiotic-resistance genes, though it can inactivate and decrease bacterial counts of antibiotic-resistant bacteria (ARB. Therefore, it was suggested that remaining ARB and/or antibiotic-resistance gene in inactivated bacterial cells after chlorine disinfection tank could be discharged into water environments.

  6. The role of drug profiles as similarity metrics: applications to repurposing, adverse effects detection and drug-drug interactions.

    Science.gov (United States)

    Vilar, Santiago; Hripcsak, George

    2017-07-01

    Explosion of the availability of big data sources along with the development in computational methods provides a useful framework to study drugs' actions, such as interactions with pharmacological targets and off-targets. Databases related to protein interactions, adverse effects and genomic profiles are available to be used for the construction of computational models. In this article, we focus on the description of biological profiles for drugs that can be used as a system to compare similarity and create methods to predict and analyze drugs' actions. We highlight profiles constructed with different biological data, such as target-protein interactions, gene expression measurements, adverse effects and disease profiles. We focus on the discovery of new targets or pathways for drugs already in the pharmaceutical market, also called drug repurposing, in the interaction with off-targets responsible for adverse reactions and in drug-drug interaction analysis. The current and future applications, strengths and challenges facing all these methods are also discussed. Biological profiles or signatures are an important source of data generation to deeply analyze biological actions with important implications in drug-related studies. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  7. Completion of a Dislocated Metric Space

    Directory of Open Access Journals (Sweden)

    P. Sumati Kumari

    2015-01-01

    Full Text Available We provide a construction for the completion of a dislocated metric space (abbreviated d-metric space; we also prove that the completion of the metric associated with a d-metric coincides with the metric associated with the completion of the d-metric.

  8. Applying of dilatometric effect for resistance welding automation

    Directory of Open Access Journals (Sweden)

    Bondarenko O. F.

    2017-06-01

    Full Text Available The important issue of resistance spot welding control to obtain high quality welded joints, especially in living tissue welding, is considered. The actual state of the issue is described and analyzed. In order to improve the quality of welded joints, the applying of dilatometric effect to control the resistance spot welding process, namely of shifting the welding electrodes, is suggested. To register the shifting, the use of modern inertial microelectromechanical sensors (MEMS is proposed. The experimental measuring system, which processes the MEMS-sensor signal and makes it suitable for use as a feedback signal, is developed. The structure and operational algorithm of the system are described. The abilities of measuring with MEMS-sensors the values of electrode shifting caused by dilatometric effect under resistance welding are assessed. These method and equipment are recommended for welding the metals, as well as for welding the living tissues. The results of preliminary studies prove the advisability and relevance of the suggested solutions.

  9. Effect of methylglyoxal on multidrug-resistant Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Katsuhiko eHayashi

    2014-04-01

    Full Text Available Honey has a complex chemistry, and its broad-spectrum antimicrobial activity varies with floral source, climate, and harvesting conditions. Methylglyoxal was identified as the dominant antibacterial component of manuka honey. Although it has been known that methylglyoxal has antibacterial activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus, there is not much information describing its activity against gram-negative bacteria. In this study, we report the effect of methylglyoxal against multidrug-resistant Pseudomonas aeruginosa (MDRP using 53 clinically isolated strains. We also assessed the effect of deleting the five multidrug efflux systems in P. aeruginosa, as well as the efflux systems in Escherichia coli and Salmonella enterica serovar Typhimurium, on MICs of methylglyoxal. Our results indicate that methylglyoxal inhibits the growth of MDRP at concentrations of 128–512 µg/ml (1.7–7.1 mM and is not recognized by drug efflux systems.

  10. Effect of structure state on the microplastic resistance of thermobimetals

    International Nuclear Information System (INIS)

    Bashnin, Yu.A.; Ulanovskij, F.B.; Shiryaeva, A.N.

    1983-01-01

    The effect of structural state on microplastic resistance of nickel alloy thermobimetals with butt oint of layers has been studied. It has been shown that a stable polygonal structure with minimum level of residual stresses is achieved in thermobimetals by a three-fold thermocyclic treatment with heating up to 400 deg C, holding during 1 hour and slow cooling up to room temperature after each cycle with a speed of 2-4 deg C per min. The stable polygonal structure of alloys-components of thermobimetals provides growth of microplastic resistance and drop of residual deflection. The maximum thermobimetal thermosensitivity is provided at 50% preliminary plastic deformation degree on thermocouples cut out along the direction of rolli

  11. Transgenerational Effects Alter Plant Defense and Resistance in Nature

    Science.gov (United States)

    Colicchio, Jack

    2017-01-01

    Trichomes, or leaf hairs, are epidermal extensions that take a variety of forms and perform many functions in plants, including herbivore defense. In this study, I document genetically determined variation, within-generation plasticity, and a direct role of trichomes in herbivore defense for Mimulus guttatus. After establishing the relationship between trichomes and herbivory, I test for transgenerational effects of wounding on trichome density and herbivore resistance. Patterns of inter-annual variation in herbivore density and the high cost of plant defense makes plant-herbivore interactions a system in which transgenerational phenotypic plasticity (TPP) is apt to evolve. Here, I demonstrate that parental damage alters offspring trichome density and herbivore resistance in nature. Moreover, this response varies between populations. This is among the first studies to demonstrate that TPP contributes to variation in nature, and also suggests that selection can modify TPP in response to local conditions. PMID:28102915

  12. Effect of structure state on the microplastic resistance of thermobimetals

    Energy Technology Data Exchange (ETDEWEB)

    Bashnin, Yu.A.; Ulanovskij, F.B.; Shiryaeva, A.N. (Moskovskij Vechernij Metallurgicheskij Inst. (USSR))

    1983-01-01

    The effect of structural state on microplastic resistance of nickel alloy thermobimetals with butt joint of layers has been studied. It has been shown that a stable polygonal structure with minimum level of residual stresses is achieved in thermobimetals by a three-fold thermocyclic treatment with heating up to 400 deg C, holding during 1 hour and slow cooling up to room temperature after each cycle with a speed of 2-4 deg C per min. The stable polygonal structure of alloys-components of thermobimetals provides growth of microplastic resistance and drop of residual deflection. The maximum thermobimetal thermosensitivity is provided at 50% preliminary plastic deformation degree on thermocouples cut out along the direction of rolli.

  13. Effects of compressibility on the resistive ballooning mode

    International Nuclear Information System (INIS)

    Hender, T.C.; Carreras, B.A.; Cooper, W.A.; Holmes, J.A.; Diamond, P.H.; Similon, P.L.

    1983-09-01

    The linear stability of the resistive ballooning mode, as described by the resistive MHD model, is investigated both analytically and numerically. When the pressure evolution is approximated by fluid convection (reduced MHD model), an instability driven by geodesic curvature, with a growth rate γ approx. eta/sup 1/3/β/sub rho//sup 2/3/, is found. For conditions relevant to the Impurity Study Experiment (ISX-B), it is shown that for modest poloidal beta (β/sub rho/ approx. = 1), high current, and relatively high temperatures, compressibility has a significant stabilizing influence, relative to the pressure convection model, for low toroidal mode number modes. However, at high β/sub rho/ (greater than or equal to 2), low current, and lower temperatures, compressibility has much less effect

  14. Social Media Metrics Importance and Usage Frequency in Latvia

    Directory of Open Access Journals (Sweden)

    Ronalds Skulme

    2017-12-01

    Full Text Available Purpose of the article: The purpose of this paper was to explore which social media marketing metrics are most often used and are most important for marketing experts in Latvia and can be used to evaluate marketing campaign effectiveness. Methodology/methods: In order to achieve the aim of this paper several theoretical and practical research methods were used, such as theoretical literature analysis, surveying and grouping. First of all, theoretical research about social media metrics was conducted. Authors collected information about social media metric grouping methods and the most frequently mentioned social media metrics in the literature. The collected information was used as the foundation for the expert surveys. The expert surveys were used to collect information from Latvian marketing professionals to determine which social media metrics are used most often and which social media metrics are most important in Latvia. Scientific aim: The scientific aim of this paper was to identify if social media metrics importance varies depending on the consumer purchase decision stage. Findings: Information about the most important and most often used social media marketing metrics in Latvia was collected. A new social media grouping framework is proposed. Conclusions: The main conclusion is that the importance and the usage frequency of the social media metrics is changing depending of consumer purchase decisions stage the metric is used to evaluate.

  15. Metric-adjusted skew information

    DEFF Research Database (Denmark)

    Liang, Cai; Hansen, Frank

    2010-01-01

    on a bipartite system and proved superadditivity of the Wigner-Yanase-Dyson skew informations for such states. We extend this result to the general metric-adjusted skew information. We finally show that a recently introduced extension to parameter values 1 ...We give a truly elementary proof of the convexity of metric-adjusted skew information following an idea of Effros. We extend earlier results of weak forms of superadditivity to general metric-adjusted skew information. Recently, Luo and Zhang introduced the notion of semi-quantum states...... of (unbounded) metric-adjusted skew information....

  16. Two classes of metric spaces

    Directory of Open Access Journals (Sweden)

    Isabel Garrido

    2016-04-01

    Full Text Available The class of metric spaces (X,d known as small-determined spaces, introduced by Garrido and Jaramillo, are properly defined by means of some type of real-valued Lipschitz functions on X. On the other hand, B-simple metric spaces introduced by Hejcman are defined in terms of some kind of bornologies of bounded subsets of X. In this note we present a common framework where both classes of metric spaces can be studied which allows us to see not only the relationships between them but also to obtain new internal characterizations of these metric properties.

  17. Observable traces of non-metricity: New constraints on metric-affine gravity

    Science.gov (United States)

    Delhom-Latorre, Adrià; Olmo, Gonzalo J.; Ronco, Michele

    2018-05-01

    Relaxing the Riemannian condition to incorporate geometric quantities such as torsion and non-metricity may allow to explore new physics associated with defects in a hypothetical space-time microstructure. Here we show that non-metricity produces observable effects in quantum fields in the form of 4-fermion contact interactions, thereby allowing us to constrain the scale of non-metricity to be greater than 1 TeV by using results on Bahbah scattering. Our analysis is carried out in the framework of a wide class of theories of gravity in the metric-affine approach. The bound obtained represents an improvement of several orders of magnitude to previous experimental constraints.

  18. The biochar effect: plant resistance to biotic stresses

    Directory of Open Access Journals (Sweden)

    YIGAL ELAD

    2012-01-01

    Full Text Available Biochar (charcoal is the solid co-product of pyrolysis, the thermal degradation of biomass in the absence of oxygen. Pyrolysis also yields gaseous and liquid biofuel products. There is a growing interest worldwide in the pyrolysis platform, for at least four reasons: (i pyrolysis can be a source of renewable biofuels; (ii many biomass waste materials can be treated by pyrolysis and thus converted into a fuel resource; (iii long-term sequestration of carbon dioxide which originated in the atmosphere may result from adding biochar to soil; and (iv biochar soil amendment contributes to improved soil fertility and crop productivity. Currently, however, very little biochar is utilized in agriculture, in part because its agronomic value in terms of crop response and soil health benefits have yet to be quantified, and because the mechanisms by which it improves soil fertility are poorly understood. The positive effects of biochar on crop productivity under conditions of extensive agriculture are frequently attributed to direct effects of biochar-supplied nutrients and to several other indirect effects, including increased water and nutrient retention, improvements in soil pH, increased soil cation exchange capacity, effects on P and S transformations and turnover, neutralization of phytotoxic compounds in the soil, improved soil physical properties, promotion of mycorrhizal fungi, and alteration of soil microbial populations and functions. Yet, the biochar effect is also evident under conditions of intensive production where many of these parameters are not limited. Biochar addition to soil alters microbial populations in the rhizosphere, albeit via mechanisms not yet understood, and may cause a shift towards beneficial microorganism populations that promote plant growth and resistance to biotic stresses. In addition to some scant evidence for biochar-induced plant protection against soilborne diseases, the induction of systemic resistance towards

  19. Software metrics: Software quality metrics for distributed systems. [reliability engineering

    Science.gov (United States)

    Post, J. V.

    1981-01-01

    Software quality metrics was extended to cover distributed computer systems. Emphasis is placed on studying embedded computer systems and on viewing them within a system life cycle. The hierarchy of quality factors, criteria, and metrics was maintained. New software quality factors were added, including survivability, expandability, and evolvability.

  20. Landscape pattern metrics and regional assessment

    Science.gov (United States)

    O'Neill, R. V.; Riitters, K.H.; Wickham, J.D.; Jones, K.B.

    1999-01-01

    The combination of remote imagery data, geographic information systems software, and landscape ecology theory provides a unique basis for monitoring and assessing large-scale ecological systems. The unique feature of the work has been the need to develop and interpret quantitative measures of spatial pattern-the landscape indices. This article reviews what is known about the statistical properties of these pattern metrics and suggests some additional metrics based on island biogeography, percolation theory, hierarchy theory, and economic geography. Assessment applications of this approach have required interpreting the pattern metrics in terms of specific environmental endpoints, such as wildlife and water quality, and research into how to represent synergystic effects of many overlapping sources of stress.

  1. Chaos-based wireless communication resisting multipath effects

    Science.gov (United States)

    Yao, Jun-Liang; Li, Chen; Ren, Hai-Peng; Grebogi, Celso

    2017-09-01

    In additive white Gaussian noise channel, chaos has been shown to be the optimal coherent communication waveform in the sense of using a very simple matched filter to maximize the signal-to-noise ratio. Recently, Lyapunov exponent spectrum of the chaotic signals after being transmitted through a wireless channel has been shown to be unaltered, paving the way for wireless communication using chaos. In wireless communication systems, inter-symbol interference caused by multipath propagation is one of the main obstacles to achieve high bit transmission rate and low bit-error rate (BER). How to resist the multipath effect is a fundamental problem in a chaos-based wireless communication system (CWCS). In this paper, a CWCS is built to transmit chaotic signals generated by a hybrid dynamical system and then to filter the received signals by using the corresponding matched filter to decrease the noise effect and to detect the binary information. We find that the multipath effect can be effectively resisted by regrouping the return map of the received signal and by setting the corresponding threshold based on the available information. We show that the optimal threshold is a function of the channel parameters and of the information symbols. Practically, the channel parameters are time-variant, and the future information symbols are unavailable. In this case, a suboptimal threshold is proposed, and the BER using the suboptimal threshold is derived analytically. Simulation results show that the CWCS achieves a remarkable competitive performance even under inaccurate channel parameters.

  2. Effect of Bi on the corrosion resistance of zirconium alloys

    International Nuclear Information System (INIS)

    Yao Meiyi; Zhou Bangxin; Li Qiang; Zhang Weipeng; Zhu Li; Zou Linghong; Zhang Jinlong; Peng Jianchao

    2014-01-01

    In order to investigate systematically the effect of Bi addition on the corrosion resistance of zirconium alloys, different zirconium-based alloys, including Zr-4 (Zr-l.5Sn-0.2Fe-0.1Cr), S5 (Zr-0.8Sn-0.35Nb-0.4Fe-0.1Cr), T5 (Zr-0.7Sn-l.0Nb-0.3Fe-0.1Cr) and Zr-1Nb, were adopted to prepare the zirconium alloys containing Bi of 0∼0.5% in mass fraction. These alloys were denoted as Zr-4 + xBi, S5 + xBi, T5 + xBi and Zr-1Nb + xBi, respectively. The corrosion behavior of these specimens was investigated by autoclave testing in lithiated water with 0.01 M LiOH or deionized water at 360 ℃/18.6 MPa and in superheated steam at 400 ℃/10.3 MPa. The microstructure of the alloys was examined by TEM and the second phase particles (SPPs) were analyzed by EDS. Microstructure observation shows that the addition of Bi promotes the precipitation of Sn as second phase particles (SPPs) because Sn is in solid solution in α-Zr matrix in Zr-4, S5 and T5 alloys. The concentration of Bi dissolved in α-Zr matrix increase with the increase of Nb in the alloys, and the excess Bi precipitates as Bi-containing SPPs. The corrosion results show that the effect of Bi addition on the corrosion behavior of different zirconium-based alloys is very complicated, depending on their compositions and corrosion conditions. In the case of higher Bi concentration in α-Zr, the zirconium alloys exhibit better corrosion resistance. However, in the case of precipitation of Bi-containing SPPs, the corrosion resistance gets worse. This indicates that the solid solution of Bi in α-Zr matrix can improve the corrosion resistance, while the precipitation of the Bi-containing SPPs is harmful to the corrosion resistance. (authors)

  3. Effect of electrode shape on grounding resistances - Part 1

    DEFF Research Database (Denmark)

    Ingeman-Nielsen, Thomas; Tomaskovicova, Sonia; Dahlin, Torleif

    2016-01-01

    Electrode grounding resistance is a major factor affecting measurement quality in electric resistivity tomography (ERT) measurements for cryospheric applications. Still, little information is available on grounding resistances in the geophysical literature, mainly because it is difficult to measure....... The focus-one protocol is a new method for estimating single electrode grounding resistances by measuring the resistance between a single electrode in an ERT array and all the remaining electrodes connected in parallel. For large arrays, the measured resistance is dominated by the grounding resistance...... of the electrode under test, the focus electrode. We have developed an equivalent circuit model formulation for the resistance measured when applying the focus-one protocol. Our model depends on the individual grounding resistances of the electrodes of the array, the mutual resistances between electrodes...

  4. Protective effects of metformin on neointima formation in insulin resistance

    Directory of Open Access Journals (Sweden)

    Yu V Pankratova

    2013-06-01

    Full Text Available Реферат по материалам статьи Lu J, Ji J, Meng H, Wang D, Jiang B, Liu L, Randell E, Adeli K, Meng QH. The protective effect and underlying mechanism of metformin on neointima formation in fructose-induced insulin resistant rats. Cardiovasc Diabetol. 2013 Apr 5;12:58. doi: 10.1186/1475-2840-12-58.

  5. Multimetric indices: How many metrics?

    Science.gov (United States)

    Multimetric indices (MMI’s) often include 5 to 15 metrics, each representing a different attribute of assemblage condition, such as species diversity, tolerant taxa, and nonnative taxa. Is there an optimal number of metrics for MMIs? To explore this question, I created 1000 9-met...

  6. Metrical Phonology: German Sound System.

    Science.gov (United States)

    Tice, Bradley S.

    Metrical phonology, a linguistic process of phonological stress assessment and diagrammatic simplification of sentence and word stress, is discussed as it is found in the English and German languages. The objective is to promote use of metrical phonology as a tool for enhancing instruction in stress patterns in words and sentences, particularly in…

  7. Extending cosmology: the metric approach

    OpenAIRE

    Mendoza, S.

    2012-01-01

    Comment: 2012, Extending Cosmology: The Metric Approach, Open Questions in Cosmology; Review article for an Intech "Open questions in cosmology" book chapter (19 pages, 3 figures). Available from: http://www.intechopen.com/books/open-questions-in-cosmology/extending-cosmology-the-metric-approach

  8. Numerical Calabi-Yau metrics

    International Nuclear Information System (INIS)

    Douglas, Michael R.; Karp, Robert L.; Lukic, Sergio; Reinbacher, Rene

    2008-01-01

    We develop numerical methods for approximating Ricci flat metrics on Calabi-Yau hypersurfaces in projective spaces. Our approach is based on finding balanced metrics and builds on recent theoretical work by Donaldson. We illustrate our methods in detail for a one parameter family of quintics. We also suggest several ways to extend our results

  9. High resolution metric imaging payload

    Science.gov (United States)

    Delclaud, Y.

    2017-11-01

    Alcatel Space Industries has become Europe's leader in the field of high and very high resolution optical payloads, in the frame work of earth observation system able to provide military government with metric images from space. This leadership allowed ALCATEL to propose for the export market, within a French collaboration frame, a complete space based system for metric observation.

  10. Measurable Control System Security through Ideal Driven Technical Metrics

    Energy Technology Data Exchange (ETDEWEB)

    Miles McQueen; Wayne Boyer; Sean McBride; Marie Farrar; Zachary Tudor

    2008-01-01

    The Department of Homeland Security National Cyber Security Division supported development of a small set of security ideals as a framework to establish measurable control systems security. Based on these ideals, a draft set of proposed technical metrics was developed to allow control systems owner-operators to track improvements or degradations in their individual control systems security posture. The technical metrics development effort included review and evaluation of over thirty metrics-related documents. On the bases of complexity, ambiguity, or misleading and distorting effects the metrics identified during the reviews were determined to be weaker than necessary to aid defense against the myriad threats posed by cyber-terrorism to human safety, as well as to economic prosperity. Using the results of our metrics review and the set of security ideals as a starting point for metrics development, we identified thirteen potential technical metrics - with at least one metric supporting each ideal. Two case study applications of the ideals and thirteen metrics to control systems were then performed to establish potential difficulties in applying both the ideals and the metrics. The case studies resulted in no changes to the ideals, and only a few deletions and refinements to the thirteen potential metrics. This led to a final proposed set of ten core technical metrics. To further validate the security ideals, the modifications made to the original thirteen potential metrics, and the final proposed set of ten core metrics, seven separate control systems security assessments performed over the past three years were reviewed for findings and recommended mitigations. These findings and mitigations were then mapped to the security ideals and metrics to assess gaps in their coverage. The mappings indicated that there are no gaps in the security ideals and that the ten core technical metrics provide significant coverage of standard security issues with 87% coverage. Based

  11. Weyl metrics and wormholes

    Energy Technology Data Exchange (ETDEWEB)

    Gibbons, Gary W. [DAMTP, University of Cambridge, Wilberforce Road, Cambridge, CB3 0WA U.K. (United Kingdom); Volkov, Mikhail S., E-mail: gwg1@cam.ac.uk, E-mail: volkov@lmpt.univ-tours.fr [Laboratoire de Mathématiques et Physique Théorique, LMPT CNRS—UMR 7350, Université de Tours, Parc de Grandmont, Tours, 37200 France (France)

    2017-05-01

    We study solutions obtained via applying dualities and complexifications to the vacuum Weyl metrics generated by massive rods and by point masses. Rescaling them and extending to complex parameter values yields axially symmetric vacuum solutions containing singularities along circles that can be viewed as singular matter sources. These solutions have wormhole topology with several asymptotic regions interconnected by throats and their sources can be viewed as thin rings of negative tension encircling the throats. For a particular value of the ring tension the geometry becomes exactly flat although the topology remains non-trivial, so that the rings literally produce holes in flat space. To create a single ring wormhole of one metre radius one needs a negative energy equivalent to the mass of Jupiter. Further duality transformations dress the rings with the scalar field, either conventional or phantom. This gives rise to large classes of static, axially symmetric solutions, presumably including all previously known solutions for a gravity-coupled massless scalar field, as for example the spherically symmetric Bronnikov-Ellis wormholes with phantom scalar. The multi-wormholes contain infinite struts everywhere at the symmetry axes, apart from solutions with locally flat geometry.

  12. Metrics for image segmentation

    Science.gov (United States)

    Rees, Gareth; Greenway, Phil; Morray, Denise

    1998-07-01

    An important challenge in mapping image-processing techniques onto applications is the lack of quantitative performance measures. From a systems engineering perspective these are essential if system level requirements are to be decomposed into sub-system requirements which can be understood in terms of algorithm selection and performance optimization. Nowhere in computer vision is this more evident than in the area of image segmentation. This is a vigorous and innovative research activity, but even after nearly two decades of progress, it remains almost impossible to answer the question 'what would the performance of this segmentation algorithm be under these new conditions?' To begin to address this shortcoming, we have devised a well-principled metric for assessing the relative performance of two segmentation algorithms. This allows meaningful objective comparisons to be made between their outputs. It also estimates the absolute performance of an algorithm given ground truth. Our approach is an information theoretic one. In this paper, we describe the theory and motivation of our method, and present practical results obtained from a range of state of the art segmentation methods. We demonstrate that it is possible to measure the objective performance of these algorithms, and to use the information so gained to provide clues about how their performance might be improved.

  13. The effect of low-dose spironolactone on resistant hypertension

    DEFF Research Database (Denmark)

    Engbaek, Mette; Hjerrild, Mette; Hallas, Jesper

    2010-01-01

    with three classes of antihypertensive drugs. The effect on blood pressure was estimated by office measurements together with serum potassium and adverse effects. The data were analyzed retrospectively. A total of 544 patients were identified; 200 were excluded because of secondary hypertension, other......Our objective was to estimate the effect of addition of low-dose spironolactone to previous antihypertensive therapy in patients with resistant hypertension. Patients had 25 to 50 mg of spironolactone once daily added to the treatment of hypertension that was uncontrolled despite previous treatment...... indications for spironolactone than hypertension, previous antihypertensive therapy with less than three drugs unless demonstrated intolerance to a third drug, insufficient compliance, and lack of follow-up data. Thus, 344 cases were included in the analysis. The population was 62.1 ± 12.8 years old, 45...

  14. Metric regularity and subdifferential calculus

    International Nuclear Information System (INIS)

    Ioffe, A D

    2000-01-01

    The theory of metric regularity is an extension of two classical results: the Lyusternik tangent space theorem and the Graves surjection theorem. Developments in non-smooth analysis in the 1980s and 1990s paved the way for a number of far-reaching extensions of these results. It was also well understood that the phenomena behind the results are of metric origin, not connected with any linear structure. At the same time it became clear that some basic hypotheses of the subdifferential calculus are closely connected with the metric regularity of certain set-valued maps. The survey is devoted to the metric theory of metric regularity and its connection with subdifferential calculus in Banach spaces

  15. Effects of different correlation metrics and preprocessing factors on small-world brain functional networks: a resting-state functional MRI study.

    Science.gov (United States)

    Liang, Xia; Wang, Jinhui; Yan, Chaogan; Shu, Ni; Xu, Ke; Gong, Gaolang; He, Yong

    2012-01-01

    Graph theoretical analysis of brain networks based on resting-state functional MRI (R-fMRI) has attracted a great deal of attention in recent years. These analyses often involve the selection of correlation metrics and specific preprocessing steps. However, the influence of these factors on the topological properties of functional brain networks has not been systematically examined. Here, we investigated the influences of correlation metric choice (Pearson's correlation versus partial correlation), global signal presence (regressed or not) and frequency band selection [slow-5 (0.01-0.027 Hz) versus slow-4 (0.027-0.073 Hz)] on the topological properties of both binary and weighted brain networks derived from them, and we employed test-retest (TRT) analyses for further guidance on how to choose the "best" network modeling strategy from the reliability perspective. Our results show significant differences in global network metrics associated with both correlation metrics and global signals. Analysis of nodal degree revealed differing hub distributions for brain networks derived from Pearson's correlation versus partial correlation. TRT analysis revealed that the reliability of both global and local topological properties are modulated by correlation metrics and the global signal, with the highest reliability observed for Pearson's-correlation-based brain networks without global signal removal (WOGR-PEAR). The nodal reliability exhibited a spatially heterogeneous distribution wherein regions in association and limbic/paralimbic cortices showed moderate TRT reliability in Pearson's-correlation-based brain networks. Moreover, we found that there were significant frequency-related differences in topological properties of WOGR-PEAR networks, and brain networks derived in the 0.027-0.073 Hz band exhibited greater reliability than those in the 0.01-0.027 Hz band. Taken together, our results provide direct evidence regarding the influences of correlation metrics and specific

  16. Improved quantum backtracking algorithms using effective resistance estimates

    Science.gov (United States)

    Jarret, Michael; Wan, Kianna

    2018-02-01

    We investigate quantum backtracking algorithms of the type introduced by Montanaro (Montanaro, arXiv:1509.02374). These algorithms explore trees of unknown structure and in certain settings exponentially outperform their classical counterparts. Some of the previous work focused on obtaining a quantum advantage for trees in which a unique marked vertex is promised to exist. We remove this restriction by recharacterizing the problem in terms of the effective resistance of the search space. In this paper, we present a generalization of one of Montanaro's algorithms to trees containing k marked vertices, where k is not necessarily known a priori. Our approach involves using amplitude estimation to determine a near-optimal weighting of a diffusion operator, which can then be applied to prepare a superposition state with support only on marked vertices and ancestors thereof. By repeatedly sampling this state and updating the input vertex, a marked vertex is reached in a logarithmic number of steps. The algorithm thereby achieves the conjectured bound of O ˜(√{T Rmax }) for finding a single marked vertex and O ˜(k √{T Rmax }) for finding all k marked vertices, where T is an upper bound on the tree size and Rmax is the maximum effective resistance encountered by the algorithm. This constitutes a speedup over Montanaro's original procedure in both the case of finding one and the case of finding multiple marked vertices in an arbitrary tree.

  17. Analysis of creep effective stress in austenitic heat resistant steel

    International Nuclear Information System (INIS)

    Park, In Duck; Nam, Ki Woo

    2002-01-01

    This paper describes the comparison of calculated effective stress with experimental one in austenitic heat resistant steels, STS310J1TB and STS310S with and without a small amount of Nb and N. Based on a solute atoms diffusion model, contribution from soluble nitrogen to the high-temperature strength was numerically examined for austenitic heat-resisting Fe-Cr-Ni-N(STS310J1TB) and Fe-Cr-Ni(STS310S) alloys. The solute atmosphere dragging stress of dislocation was calculated in optional dislocation velocity of STS310J1TB and STS310S at 650 degree C, 675 degree C and 700 degree C. As a result of the numerical calculation, the solute atmosphere dragging stress of STS310J1TB was about 50 times larger than that of STS310S. When the temperature became high, the maximum value of solute atmosphere dragging stress was small and the velocity of moving dislocation was fast. From the relationship between the dislocation rate and the solute atmosphere dragging stress, the relation of both was proportional and the inclination is about 1 in the level with low velocity of moving dislocation. From above results, the mechanism of dislocation movement in STS310J1TB was the solute atmosphere dragging stress. The solute atmosphere dragging stress, which was calculated from the numerical calculation was close to the effect stress in stress relaxation tests

  18. Effect of chitosan on resist printing of cotton fabrics with reactive dyes

    African Journals Online (AJOL)

    The concentration of chitosan, types of resist agent, curing temperature and curing time were varied to determine their effects on resist-printed cotton fabrics. An optimal chitosan concentration of 1.6% resulted in the greatest resist effect on printed cotton fabrics. For mixtures, a 6:4 ratio of citric acid : chitosan and an 8:2 ...

  19. Effect of chitosan on resist printing of cotton fabrics with reactive dyes

    African Journals Online (AJOL)

    user

    2011-02-21

    Feb 21, 2011 ... levels may cause the dyes to form a partial covalent bond with chitosan, thereby diminishing the resist-printing effect. In such a case, the resist printing would not be linear as a function of chitosan concentration. Red 184 exhibited the highest resist-printing effect, followed by. Blue 204 and Yellow 143.

  20. Scalar metric fluctuations in space-time matter inflation

    International Nuclear Information System (INIS)

    Anabitarte, Mariano; Bellini, Mauricio

    2006-01-01

    Using the Ponce de Leon background metric, which describes a 5D universe in an apparent vacuum: G-bar AB =0, we study the effective 4D evolution of both, the inflaton and gauge-invariant scalar metric fluctuations, in the recently introduced model of space-time matter inflation

  1. METRICS DEVELOPMENT FOR PATENTS.

    Science.gov (United States)

    Veiga, Daniela Francescato; Ferreira, Lydia Masako

    2015-01-01

    To develop a proposal for metrics for patents to be applied in assessing the postgraduate programs of Medicine III - Capes. From the reading and analysis of the 2013 area documents of all the 48 areas of Capes, a proposal for metrics for patents was developed to be applied in Medicine III programs. Except for the areas Biotechnology, Food Science, Biological Sciences III, Physical Education, Engineering I, III and IV and Interdisciplinary, most areas do not adopt a scoring system for patents. The proposal developed was based on the criteria of Biotechnology, with adaptations. In general, it will be valued, in ascending order, the deposit, the granting and licensing/production. It will also be assigned higher scores to patents registered abroad and whenever there is a participation of students. This proposal can be applied to the item Intellectual Production of the evaluation form, in subsection Technical Production/Patents. The percentage of 10% for academic programs and 40% for Masters Professionals should be maintained. The program will be scored as Very Good when it reaches 400 points or over; Good, between 200 and 399 points; Regular, between 71 and 199 points; Weak up to 70 points; Insufficient, no punctuation. Desenvolver uma proposta de métricas para patentes a serem aplicadas na avaliação dos Programas de Pós-Graduação da Área Medicina III - Capes. A partir da leitura e análise dos documentos de área de 2013 de todas as 48 Áreas da Capes, desenvolveu-se uma proposta de métricas para patentes, a ser aplicada na avaliação dos programas da área. Constatou-se que, com exceção das áreas Biotecnologia, Ciência de Alimentos, Ciências Biológicas III, Educação Física, Engenharias I, III e IV e Interdisciplinar, a maioria não adota sistema de pontuação para patentes. A proposta desenvolvida baseou-se nos critérios da Biotecnologia, com adaptações. De uma forma geral, foi valorizado, em ordem crescente, o depósito, a concessão e o

  2. A Metric for Heterotic Moduli

    Science.gov (United States)

    Candelas, Philip; de la Ossa, Xenia; McOrist, Jock

    2017-12-01

    Heterotic vacua of string theory are realised, at large radius, by a compact threefold with vanishing first Chern class together with a choice of stable holomorphic vector bundle. These form a wide class of potentially realistic four-dimensional vacua of string theory. Despite all their phenomenological promise, there is little understanding of the metric on the moduli space of these. What is sought is the analogue of special geometry for these vacua. The metric on the moduli space is important in phenomenology as it normalises D-terms and Yukawa couplings. It is also of interest in mathematics, since it generalises the metric, first found by Kobayashi, on the space of gauge field connections, to a more general context. Here we construct this metric, correct to first order in {α^{\\backprime}}, in two ways: first by postulating a metric that is invariant under background gauge transformations of the gauge field, and also by dimensionally reducing heterotic supergravity. These methods agree and the resulting metric is Kähler, as is required by supersymmetry. Checking the metric is Kähler is intricate and the anomaly cancellation equation for the H field plays an essential role. The Kähler potential nevertheless takes a remarkably simple form: it is the Kähler potential of special geometry with the Kähler form replaced by the {α^{\\backprime}}-corrected hermitian form.

  3. A multi-metric assessment of environmental contaminant exposure and effects in an urbanized reach of the Charles River near Watertown, Massachusetts

    Science.gov (United States)

    Smith, Stephen B.; Anderson, Patrick J.; Baumann, Paul C.; DeWeese, Lawrence R.; Goodbred, Steven L.; Coyle, James J.; Smith, David S.

    2012-01-01

    The Charles River Project provided an opportunity to simultaneously deploy a combination of biomonitoring techniques routinely used by the U.S. Geological Survey National Water Quality Assessment Program, the Biomonitoring of Environmental Status and Trends Project, and the Contaminant Biology Program at an urban site suspected to be contaminated with polycyclic aromatic hydrocarbons. In addition to these standardized methods, additional techniques were used to further elucidate contaminant exposure and potential impacts of exposure on biota. The purpose of the study was to generate a comprehensive, multi-metric data set to support assessment of contaminant exposure and effects at the site. Furthermore, the data set could be assessed to determine the relative performance of the standardized method suites typically used by the National Water Quality Assessment Program and the Biomonitoring of Environmental Status and Trends Project, as well as the additional biomonitoring methods used in the study to demonstrate ecological effects of contaminant exposure. The Contaminant Effects Workgroup, an advisory committee of the U.S. Geological Survey/Contaminant Biology Program, identified polycyclic aromatic hydrocarbons as the contaminant class of greatest concern in urban streams of all sizes. The reach of the Charles River near Watertown, Massachusetts, was selected as the site for this study based on the suspected presence of polycyclic aromatic hydrocarbon contamination and the presence of common carp (Cyprinus carpio), largemouth bass (Micropterus salmoides), and white sucker (Catostomus commersoni). All of these fish have extensive contaminant-exposure profiles related to polycyclic aromatic hydrocarbons and other environmental contaminants. This project represented a collaboration of universities, Department of the Interior bureaus including multiple components of the USGS (Biological Resources Discipline and Water Resources Discipline Science Centers, the

  4. Implications of Metric Choice for Common Applications of Readmission Metrics

    OpenAIRE

    Davies, Sheryl; Saynina, Olga; Schultz, Ellen; McDonald, Kathryn M; Baker, Laurence C

    2013-01-01

    Objective. To quantify the differential impact on hospital performance of three readmission metrics: all-cause readmission (ACR), 3M Potential Preventable Readmission (PPR), and Centers for Medicare and Medicaid 30-day readmission (CMS).

  5. Effect of Rolling Resistance in Dem Models With Spherical Bodies

    Directory of Open Access Journals (Sweden)

    Dubina Radek

    2016-12-01

    Full Text Available The rolling resistance is an artificial moment arising on the contact of two discrete elements which mimics resistance of two grains of complex shape in contact rolling relatively to each other. The paper investigates the influence of rolling resistance on behaviour of an assembly of spherical discrete elements. Besides the resistance to rolling, the contacts between spherical particles obey the Hertzian law in normal straining and Coulomb model of friction in shear.

  6. Issues in Benchmark Metric Selection

    Science.gov (United States)

    Crolotte, Alain

    It is true that a metric can influence a benchmark but will esoteric metrics create more problems than they will solve? We answer this question affirmatively by examining the case of the TPC-D metric which used the much debated geometric mean for the single-stream test. We will show how a simple choice influenced the benchmark and its conduct and, to some extent, DBMS development. After examining other alternatives our conclusion is that the “real” measure for a decision-support benchmark is the arithmetic mean.

  7. Background metric in supergravity theories

    International Nuclear Information System (INIS)

    Yoneya, T.

    1978-01-01

    In supergravity theories, we investigate the conformal anomaly of the path-integral determinant and the problem of fermion zero modes in the presence of a nontrivial background metric. Except in SO(3) -invariant supergravity, there are nonvanishing conformal anomalies. As a consequence, amplitudes around the nontrivial background metric contain unpredictable arbitrariness. The fermion zero modes which are explicitly constructed for the Euclidean Schwarzschild metric are interpreted as an indication of the supersymmetric multiplet structure of a black hole. The degree of degeneracy of a black hole is 2/sup 4n/ in SO(n) supergravity

  8. Generalized Painleve-Gullstrand metrics

    Energy Technology Data Exchange (ETDEWEB)

    Lin Chunyu [Department of Physics, National Cheng Kung University, Tainan 70101, Taiwan (China)], E-mail: l2891112@mail.ncku.edu.tw; Soo Chopin [Department of Physics, National Cheng Kung University, Tainan 70101, Taiwan (China)], E-mail: cpsoo@mail.ncku.edu.tw

    2009-02-02

    An obstruction to the implementation of spatially flat Painleve-Gullstrand (PG) slicings is demonstrated, and explicitly discussed for Reissner-Nordstroem and Schwarzschild-anti-deSitter spacetimes. Generalizations of PG slicings which are not spatially flat but which remain regular at the horizons are introduced. These metrics can be obtained from standard spherically symmetric metrics by physical Lorentz boosts. With these generalized PG metrics, problematic contributions to the imaginary part of the action in the Parikh-Wilczek derivation of Hawking radiation due to the obstruction can be avoided.

  9. Daylight metrics and energy savings

    Energy Technology Data Exchange (ETDEWEB)

    Mardaljevic, John; Heschong, Lisa; Lee, Eleanor

    2009-12-31

    The drive towards sustainable, low-energy buildings has increased the need for simple, yet accurate methods to evaluate whether a daylit building meets minimum standards for energy and human comfort performance. Current metrics do not account for the temporal and spatial aspects of daylight, nor of occupants comfort or interventions. This paper reviews the historical basis of current compliance methods for achieving daylit buildings, proposes a technical basis for development of better metrics, and provides two case study examples to stimulate dialogue on how metrics can be applied in a practical, real-world context.

  10. Effect of paint on vapour resistivity in plaster

    Directory of Open Access Journals (Sweden)

    de Villanueva, L.

    2008-12-01

    Full Text Available The vapour resistivity of plaster coatings such as paint and their effectiveness as water repellents were studied in several types of plaster. To this end, painted, unpainted and pigmented specimens were tested. Experimental values were collected on diffusion and vapour permeability, or its inverse, water vapour resistivity.The data obtained were very useful for evaluating moisture exchange between plaster and the surrounding air, both during initial drying and throughout the life of the material. They likewise served as a basis for ensuring the proper evacuation of water vapour in walls, and use of the capacity of the porous network in plaster products to regulate moisture content or serve as a water vapour barrier to avoid condensation.Briefly, the research showed that pigments, water-based paints and silicon-based water repellents scantly raised vapour resistance. Plastic paints, enamels and lacquers, however, respectively induced five-, ten- and twenty-fold increases in vapour resistivity, on average.Se estudia el fenómeno de la resistividad al vapor de los de yeso y el efecto impermeabilizante que producen los recubrimientos de pintura sobre diversos tipos de yeso y escayola. Para ello, se ensayan probetas desnudas y recubiertas con distintos tipos de pintura, así como coloreados en masa. Se obtienen valores experimentales de la difusividad o permeabilidad al vapor o su inverso la resistividad al vapor de agua.Los datos obtenidos son muy útiles para valorar el fenómeno del intercambio de humedad entre el yeso y el ambiente, tanto durante el proceso de su secado inicial, como en el transcurso de su vida. Así como para disponer soluciones adecuadas para la evacuación del vapor de agua a través de los cerramientos, para utilizar la capacidad de regulación de la humedad, que proporciona el entramado poroso de los productos de yeso, o para impedir el paso del vapor de agua y evitar condensaciones.Como resumen de la investigación, se

  11. Effect of mechanical properties on erosion resistance of ductile materials

    Science.gov (United States)

    Levin, Boris Feliksovih

    incorporating this parameter into a new erosion model, good correlation was observed with experimentally measured erosion rates. An increase in area under the microhardness curve led to an increase in erosion resistance. It was shown that an increase in hardness below the eroded surface occurs mainly due to the strain-rate hardening effect. Strain-rate sensitivities of tested materials were estimated from the nanoindentation tests and showed a decrease with an increase in materials hardness. Also, materials combining high hardness and strain-rate sensitivity may offer good erosion resistance. A methodology is presented to determine the proper mechanical properties to incorporate into the erosion parameter based on the physical model of the erosion mechanism in ductile materials.

  12. Multi-polar resistance switching and memory effect in copper phthalocyanine junctions

    International Nuclear Information System (INIS)

    Qiao Shi-Zhu; Kang Shi-Shou; Li Qiang; Zhong Hai; Kang Yun; Yu Shu-Yun; Han Guang-Bing; Yan Shi-Shen; Mei Liang-Mo; Qin Yu-Feng

    2014-01-01

    Copper phthalocyanine junctions, fabricated by magnetron sputtering and evaporating methods, show multi-polar (unipolar and bipolar) resistance switching and the memory effect. The multi-polar resistance switching has not been observed simultaneously in one organic material before. With both electrodes being cobalt, the unipolar resistance switching is universal. The high resistance state is switched to the low resistance state when the bias reaches the set voltage. Generally, the set voltage increases with the thickness of copper phthalocyanine and decreases with increasing dwell time of bias. Moreover, the low resistance state could be switched to the high resistance state by absorbing the phonon energy. The stability of the low resistance state could be tuned by different electrodes. In Au/copper phthalocyanine/Co system, the low resistance state is far more stable, and the bipolar resistance switching is found. Temperature dependence of electrical transport measurements demonstrates that there are no obvious differences in the electrical transport mechanism before and after the resistance switching. They fit quite well with Mott variable range hopping theory. The effect of Al 2 O 3 on the resistance switching is excluded by control experiments. The holes trapping and detrapping in copper phthalocyanine layer are responsible for the resistance switching, and the interfacial effect between electrodes and copper phthalocyanine layer affects the memory effect. (interdisciplinary physics and related areas of science and technology)

  13. Transgenerational effects alter plant defence and resistance in nature.

    Science.gov (United States)

    Colicchio, J

    2017-04-01

    Trichomes, or leaf hairs, are epidermal extensions that take a variety of forms and perform many functions in plants, including herbivore defence. In this study, I document genetically determined variation, within-generation plasticity, and a direct role of trichomes in herbivore defence for Mimulus guttatus. After establishing the relationship between trichomes and herbivory, I test for transgenerational effects of wounding on trichome density and herbivore resistance. Patterns of interannual variation in herbivore density and the high cost of plant defence makes plant-herbivore interactions a system in which transgenerational phenotypic plasticity (TPP) is apt to evolve. Here, I demonstrate that parental damage alters offspring trichome density and herbivore resistance in nature. Moreover, this response varies between populations. This is among the first studies to demonstrate that TPP contributes to variation in nature, and also suggests that selection can modify TPP in response to local conditions. © 2017 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2017 European Society For Evolutionary Biology.

  14. Resistivity and thickness effects in dendritic web silicon solar cells

    Science.gov (United States)

    Meier, D. L.; Hwang, J. M.; Greggi, J.; Campbell, R. B.

    1987-01-01

    The decrease of minority carrier lifetime as resistivity decreases in dendritic-web silicon solar cells is addressed. This variation is shown to be consistent with the presence of defect levels in the bandgap which arise from extended defects in the web material. The extended defects are oxide precipitates (SiOx) and the dislocation cores they decorate. Sensitivity to this background distribution of defect levels increases with doping because the Fermi level moves closer to the majority carrier band edge. For high-resistivity dendritic-web silicon, which has a low concentration of these extended defects, cell efficiencies as high as 16.6 percent (4 sq cm, 40 ohm-cm boron-doped base, AM1.5 global, 100 mW/sq cm, 25 C JPL LAPSS1 measurement) and a corresponding electron lifetime of 38 microsec have been obtained. Thickness effects occur in bifacial cell designs and in designs which use light trapping. In some cases, the dislocation/precipitate defect can be passivated through the full thickness of web cells by hydrogen ion implantation.

  15. Fringe effect of electrical capacitance and resistance tomography sensors

    International Nuclear Information System (INIS)

    Sun, Jiangtao; Yang, Wuqiang

    2013-01-01

    Because of the ‘soft-field’ nature, all electrical tomography sensors suffer from electric field distortion, i.e. the fringe effect. In electrical resistance tomography (ERT) sensors, small pin electrodes are commonly used. It is well known that the pin electrodes result in severe electric field distortion or the fringe effect, and the sensing region of such an ERT sensor spreads out of the pin electrode plane to a large volume. This is also true for electrical capacitance tomography (ECT) sensors, even though it is less severe because of larger electrodes and grounded end guards used. However, when the length of electrodes in an ECT sensor without guards is reduced to almost the same dimension as those in an ERT sensor, the fringe effect is equally obvious. To investigate the fringe effect of ERT and ECT sensors with and without guards, simulations were carried out with different length of electrodes and the results are compared with the corresponding 2D simulation. It is concluded that ECT and ERT sensors with longer electrodes have less fringe effect. Because grounded end guards are effective in reducing the fringe effect of ECT sensors, we propose to apply grounded guards in ERT sensors and integrate ECT and ERT sensors together. Simulation results reveal that ERT sensors with grounded guards have less fringe effect. While commonly current excitation is used with ERT sensors, we propose voltage excitation instead to apply the grounded guards. The feasibility of this approach has been verified by experiment. Finally, a common structure for reducing the fringe effect is proposed for ECT and ERT sensors for the first time to simplify the sensor structure and reduce the mutual interference in ECT/ERT dual-modality measurements. (paper)

  16. Effect of ultraviolet illumination on metal oxide resistive memory

    KAUST Repository

    Duran Retamal, Jose Ramon

    2014-12-22

    We investigate the photoelectrical and resistive switching properties of Pt/ZnO/Pt capacitor operated in unipolar mode under ultraviolet (UV) illumination. The oxygen photodesorption under UV illumination explains the photoconduction observed in initial and high resistance states. Meanwhile, oxygen readsorption at surface-related defects justifies the different photoresponses dynamics in both states. Finally, UV illumination significantly reduces the variations of resistance in high resistance state, set voltage and reset voltage by 58%, 33%, and 25%, respectively, stabilizing Pt/ZnO/Pt capacitor. Our findings in improved switching uniformity via UV light give physical insight into designing resistive memory devices.

  17. Effect of ultraviolet illumination on metal oxide resistive memory

    KAUST Repository

    Duran Retamal, Jose Ramon; Kang, Chen-Fang; Ho, Chih-Hsiang; Ke, Jr-Jian; Chang, Wen-Yuan; He, Jr-Hau

    2014-01-01

    We investigate the photoelectrical and resistive switching properties of Pt/ZnO/Pt capacitor operated in unipolar mode under ultraviolet (UV) illumination. The oxygen photodesorption under UV illumination explains the photoconduction observed in initial and high resistance states. Meanwhile, oxygen readsorption at surface-related defects justifies the different photoresponses dynamics in both states. Finally, UV illumination significantly reduces the variations of resistance in high resistance state, set voltage and reset voltage by 58%, 33%, and 25%, respectively, stabilizing Pt/ZnO/Pt capacitor. Our findings in improved switching uniformity via UV light give physical insight into designing resistive memory devices.

  18. Standardised metrics for global surgical surveillance.

    Science.gov (United States)

    Weiser, Thomas G; Makary, Martin A; Haynes, Alex B; Dziekan, Gerald; Berry, William R; Gawande, Atul A

    2009-09-26

    Public health surveillance relies on standardised metrics to evaluate disease burden and health system performance. Such metrics have not been developed for surgical services despite increasing volume, substantial cost, and high rates of death and disability associated with surgery. The Safe Surgery Saves Lives initiative of WHO's Patient Safety Programme has developed standardised public health metrics for surgical care that are applicable worldwide. We assembled an international panel of experts to develop and define metrics for measuring the magnitude and effect of surgical care in a population, while taking into account economic feasibility and practicability. This panel recommended six measures for assessing surgical services at a national level: number of operating rooms, number of operations, number of accredited surgeons, number of accredited anaesthesia professionals, day-of-surgery death ratio, and postoperative in-hospital death ratio. We assessed the feasibility of gathering such statistics at eight diverse hospitals in eight countries and incorporated them into the WHO Guidelines for Safe Surgery, in which methods for data collection, analysis, and reporting are outlined.

  19. Let's Make Metric Ice Cream

    Science.gov (United States)

    Zimmerman, Marianna

    1975-01-01

    Describes a classroom activity which involved sixth grade students in a learning situation including making ice cream, safety procedures in a science laboratory, calibrating a thermometer, using metric units of volume and mass. (EB)

  20. Recombination: An important effect in multigap resistive plate chambers

    International Nuclear Information System (INIS)

    Doroud, K.; Afarideh, H.; Hatzifotiadou, D.; Rahighi, J.; Williams, M.C.S.; Zichichi, A.

    2009-01-01

    We have simulated the gas avalanche in a multigap resistive plate chamber (MRPC). The results were then compared with our data from the MRPC . Up to now, the total amount of charge produced in a gas gap is considered to be given by the total number of positive ions generated by the gas avalanches. However, the total charge generated by the simulation program is much too large and is in conflict with our data. Our data indicate that nearly 100% of the negative ions recombine with the positive ions. The recombination effect dramatically reduces the amount of charge in the gas gap: a very important feature for MRPC technology especially for the rate capability.

  1. Effect of specific resistance training on musculoskeletal pain symptoms

    DEFF Research Database (Denmark)

    Pedersen, Mogens Theisen; Andersen, Lars Louis; Jørgensen, Marie Birk

    2013-01-01

    .16, p = 0.045), and there was a significant dose-response relationship between training volume per session and change in pain index (ß = -0.20, p = 0.034). In contrast, training attendance (mean 1.69 sessions per week, SD = 0.8) was not significantly related to the change in pain index. In conclusion......, achieving higher accumulated training volumes was important for reducing musculoskeletal pain in female office workers. The training volume per session should be optimized by securing a load at 10-15 repetition maximum and adhering to principles of progressive overload.......ABSTRACT: Pedersen, MT, Andersen, LL, Jørgensen, MB, Søgaard, K, and Sjøgaard, G. Effect of specific resistance training on musculoskeletal pain symptoms: Dose-response relationship. J Strength Cond Res 27(1): 229-235, 2013-The purpose of this study was to investigate the dose-response of strength...

  2. Effects of rational surface density on resistive g turbulence

    International Nuclear Information System (INIS)

    Beklemishev, A.D.; Sugama, H.; Horton, W.

    1993-01-01

    The Beklemishev-Horton theory states that the anomalous transport coefficient is proportional to the density of rational surfaces provided that the interaction between the modes localized around different rational surfaces is weak compared with modes of the same helicity. The authors examine the effects of the density of states ρ using resistive g turbulence in 2D (single-helicity) and 3D (multi-helicity) simulations. They find that the modes with different helicities do not equipartition the available energy, but rather the coalescence or inverse cascade effect is strong so that a few low order mode rational surfaces receive most of the energy. The quasilinear flattening at the surfaces is a strong effect and they use bifurcation theory to derive that the effective diffusivity increases as χ eff = χ 0 ρ/(1 - Cρ) where C is a constant determined by interaction integrals. For a sufficiently high density of states Cρ ≤ 1, the higher order nonlinear interaction must be taken into account

  3. Experiential space is hardly metric

    Czech Academy of Sciences Publication Activity Database

    Šikl, Radovan; Šimeček, Michal; Lukavský, Jiří

    2008-01-01

    Roč. 2008, č. 37 (2008), s. 58-58 ISSN 0301-0066. [European Conference on Visual Perception. 24.08-28.08.2008, Utrecht] R&D Projects: GA ČR GA406/07/1676 Institutional research plan: CEZ:AV0Z70250504 Keywords : visual space perception * metric and non-metric perceptual judgments * ecological validity Subject RIV: AN - Psychology

  4. Coverage Metrics for Model Checking

    Science.gov (United States)

    Penix, John; Visser, Willem; Norvig, Peter (Technical Monitor)

    2001-01-01

    When using model checking to verify programs in practice, it is not usually possible to achieve complete coverage of the system. In this position paper we describe ongoing research within the Automated Software Engineering group at NASA Ames on the use of test coverage metrics to measure partial coverage and provide heuristic guidance for program model checking. We are specifically interested in applying and developing coverage metrics for concurrent programs that might be used to support certification of next generation avionics software.

  5. Phantom metrics with Killing spinors

    Directory of Open Access Journals (Sweden)

    W.A. Sabra

    2015-11-01

    Full Text Available We study metric solutions of Einstein–anti-Maxwell theory admitting Killing spinors. The analogue of the IWP metric which admits a space-like Killing vector is found and is expressed in terms of a complex function satisfying the wave equation in flat (2+1-dimensional space–time. As examples, electric and magnetic Kasner spaces are constructed by allowing the solution to depend only on the time coordinate. Euclidean solutions are also presented.

  6. Effects of different correlation metrics and preprocessing factors on small-world brain functional networks: a resting-state functional MRI study.

    Directory of Open Access Journals (Sweden)

    Xia Liang

    Full Text Available Graph theoretical analysis of brain networks based on resting-state functional MRI (R-fMRI has attracted a great deal of attention in recent years. These analyses often involve the selection of correlation metrics and specific preprocessing steps. However, the influence of these factors on the topological properties of functional brain networks has not been systematically examined. Here, we investigated the influences of correlation metric choice (Pearson's correlation versus partial correlation, global signal presence (regressed or not and frequency band selection [slow-5 (0.01-0.027 Hz versus slow-4 (0.027-0.073 Hz] on the topological properties of both binary and weighted brain networks derived from them, and we employed test-retest (TRT analyses for further guidance on how to choose the "best" network modeling strategy from the reliability perspective. Our results show significant differences in global network metrics associated with both correlation metrics and global signals. Analysis of nodal degree revealed differing hub distributions for brain networks derived from Pearson's correlation versus partial correlation. TRT analysis revealed that the reliability of both global and local topological properties are modulated by correlation metrics and the global signal, with the highest reliability observed for Pearson's-correlation-based brain networks without global signal removal (WOGR-PEAR. The nodal reliability exhibited a spatially heterogeneous distribution wherein regions in association and limbic/paralimbic cortices showed moderate TRT reliability in Pearson's-correlation-based brain networks. Moreover, we found that there were significant frequency-related differences in topological properties of WOGR-PEAR networks, and brain networks derived in the 0.027-0.073 Hz band exhibited greater reliability than those in the 0.01-0.027 Hz band. Taken together, our results provide direct evidence regarding the influences of correlation metrics

  7. Stabilization of ideal plasma resistive wall modes in cylindrical geometry: The effect of resistive layers

    International Nuclear Information System (INIS)

    Finn, J.M.

    1995-01-01

    A cylindrical model with finite beta having an external resonant ideal magnetohydrodynamic instability has been constructed. This resonant mode has a mode rational surface, where the safety factor q equals m/n, within the plasma. In this model, the perturbed radial magnetic field for the ideal mode is nonzero between the mode rational surface and the wall, even though it must vanish at the mode rational surface. This property of the mode is in common with the toroidal external kink. Results are presented showing that in the parameter range for which this ideal mode is stable with a conducting wall but unstable with the wall at infinity, a resistive wall mode persists. However, in the presence of plasma resistivity in a resistive layer about the mode rational surface, this resistive wall mode can be stabilized by a plasma rotation frequency of order a nominal resistive instability growth rate. Furthermore, the stabilization occurs in a large gap in wall position or beta. It is also shown that for the ideal resonant mode, as well as resistive plasma modes and nonresonant ideal plasma modes, there is a maximum value of plasma rotation above which there is no stability gap. Discussions are presented suggesting that these properties may hold for the toroidal external kink. copyright 1995 American Institute of Physics

  8. Effect of implanted doses of N+-ions on the contact resistance of copper contacts

    International Nuclear Information System (INIS)

    Dubravec, B.; Kovac, P.; Lipka, F.; Padysak, M.

    1997-01-01

    The paper deals with the effect of implanted doses of N + ions on the contact resistance. Dependencies of the contact resistance versus contact force R c =f(F c ) and microhardness of implanted surfaces were measured for three implanted profiles. The influence of the aggressive environs on the contact resistance of implanted contact is given too

  9. Effect of whole body resistance training on arterial compliance in young men.

    NARCIS (Netherlands)

    Rakobowchuk, M.; McGowan, C.L.; Groot, P.C.E. de; Bruinsma, D.; Hartman, J.W.; Phillips, S.M.; MacDonald, M.J.

    2005-01-01

    The effect of resistance training on arterial stiffening is controversial. We tested the hypothesis that resistance training would not alter central arterial compliance. Young healthy men (age, 23 +/- 3.9 (mean +/- s.e.m.) years; n = 28,) were whole-body resistance trained five times a week for 12

  10. Effect of radiation decontamination on drug-resistant bacteria

    International Nuclear Information System (INIS)

    Ito, Hitoshi

    2006-01-01

    More than 80% of food poisoning bacteria such as Salmonella are reported as antibiotic-resistant to at least one type antibiotic, and more than 50% as resistant to two or more. For the decontamination of food poisoning bacteria in foods, radiation resistibility on drug-resistant bacteria were investigated compared with drug-sensitive bacteria. Possibility on induction of drug-resistant mutation by radiation treatment was also investigated. For these studies, type strains of Escherichia coli S2, Salmonella enteritidis YK-2 and Staphylococcus aureus H12 were used to induce drug-resistant strains with penicillin G. From the study of radiation sensitivity on the drug-resistant strain induced from E. coli S2, D 10 value was obtained to be 0.20 kGy compared with 0.25 kGy at parent strain. On S. enteritidis YK-2, D 10 value was obtained to be 0.14 kGy at drug-resistant strain compared with 0.16 kGy at parent strain. D 10 value was also obtained to be 0.15 kGy at drug-resistant strain compared with 0.21 kGy at parent strain of St. aureus H12. Many isolates of E. coli 157:H7 or other type of E. coli from meats such as beef were resistant to penicillin G, and looked to be no relationship on radiation resistivities between drug-resistant strains and sensitive strains. On the study of radiation sensitivity on E. coli S2 at plate agars containing antibiotics, higher survival fractions were obtained at higher doses compared with normal plate agar. The reason of higher survival fractions at higher doses on plate agar containing antibiotics should be recovery of high rate of injured cells by the relay of cell division, and drug-resistant strains by mutation are hardly induced by irradiation. (author)

  11. Effects of pomegranate seed oil followed by resistance exercise on insulin resistance and lipid profile in non-athletic men

    Directory of Open Access Journals (Sweden)

    Fereshteh Shahidi

    2017-08-01

    Full Text Available Background: Although some studies have reported the health-related benefits for the pomegranate seed oil (PSO, there is not enough information on its combined effect with exercise. Therefore, in this study the effect of supplementation with pomegranate seed oil followed by resistance exercise on insulin resistance and lipid profile was considered in non-athletes men. Materials and Methods: In this semi-experimental double-blind randomized study non-athletic male (n=14 were divided into two groups: Exercise+Supplementation (n=7 and Exercise +Placebo (n=7. Both groups performed resistance training for 4 weeks (3 sessions per week. The experimental group consumed 2 capsules of pomegranate seed oil (400 mg and the control group received 2 placebo capsules daily. Glucose, fasting insulin, total cholesterol, triglycerides, LDL-C, HDL-C, were measured at the beginning and end of the study. Insulin resistance was estimated using homeostasis formula (HOMA-IR. Results: While the average concentration of HDL-C in Supplement+Exercise group was significantly increased compared to pre-test, no significant increase was seen compared to Placebo + Exercise group (P<0.05. Between and within group comparison for the changes in total cholesterol, triglycerides, LDL-C, glucose, fasting insulin and insulin resistance was not significant. Conclusion: According to the results, it can be concluded that 4 weeks of resistance training followed by PSO supplementation, except for HDL-C, has no significant effect on the other lipid profiles and insulin resistance in healthy non-athlete men.

  12. Degraded visual environment image/video quality metrics

    Science.gov (United States)

    Baumgartner, Dustin D.; Brown, Jeremy B.; Jacobs, Eddie L.; Schachter, Bruce J.

    2014-06-01

    A number of image quality metrics (IQMs) and video quality metrics (VQMs) have been proposed in the literature for evaluating techniques and systems for mitigating degraded visual environments. Some require both pristine and corrupted imagery. Others require patterned target boards in the scene. None of these metrics relates well to the task of landing a helicopter in conditions such as a brownout dust cloud. We have developed and used a variety of IQMs and VQMs related to the pilot's ability to detect hazards in the scene and to maintain situational awareness. Some of these metrics can be made agnostic to sensor type. Not only are the metrics suitable for evaluating algorithm and sensor variation, they are also suitable for choosing the most cost effective solution to improve operating conditions in degraded visual environments.

  13. Effects of resistive bodies on DC electrical soundings

    Directory of Open Access Journals (Sweden)

    L. Alfano

    1996-06-01

    Full Text Available Some deep DC electrical soundings, performed in alpine and apenninic areas with the continuous polar dipole-dipole spread, show apparent resistivity curves with positive slopes. Measured values of apparent resistivity reach 30000 Wm. Applying the "surface charges" method we developed three dimensional mathematical models, by means of which we can state simple rules for determining the minimum extensions of the deep resistive bodies, fundamental information for a more precise interpretation of the field results.

  14. Effect of anomalous resistivity on the dynamics of plasma switching

    Energy Technology Data Exchange (ETDEWEB)

    Kingsep, A [Kurchatov Institute, Moscow (Russian Federation); Munier, A [Centre d` Etudes Limeil-Vaneton, Villeneuve St. Georges (France)

    1997-12-31

    Some of the conditions for electron MHD are recollected, and it is shown how this leads to anomalous resistivity which may play an important role in the dynamics of POS. It has been shown that not only the order of value of the resistance of the plasma-filled diode but rather basic scalings have to be changed in the regime of essential anomalous resistivity. (author). 11 refs.

  15. Risk assessment of UVB effects on resistance to infectious diseases

    International Nuclear Information System (INIS)

    Garssen, J.; Goettsch, W.; Slob, W.; Loveren, H. van; de Gruijl, F.

    1996-01-01

    The aim of this study was to develop a quantitative risk assessment of lowered resistance to infections in humans due to (solar) ultraviolet B (UVB) exposure. We followed the steps for risk assessment as defined by the U.S. National Academy of Sciences: (1) hazard identification, (2) dose-response assessment, (3) exposure assessment, and (4) risk characterization. For step 1, the suppressory effects of UVB radiation on the immune system has been reviewed, supplemented with new data, and analyzed. Experiments on UV-induced immunosuppression cannot be performed with humans for ethical reasons, but herpes simplex virus infection appears to be the human paradigm. Thus, UVB radiation appears to be a potential hazard to immunologic functions. Step 2 is crucial, but dose-response relationships for infections have never been measured in humans. We used our earlier dose-response rat data for suppression of lymphocyte stimulation and computed that the UVB dose resulting in a 50% reduction of lymphocyte stimulation by Listeria monocytogenes is 6.800 J/m 2 . Using mixed skin lymphocyte response assays we found that humans are 3.8 times less sensitive than rats (interspecies variation [IEV]). To account for the 2.5 percentile of most susceptible individuals in a population, an additional factor (intraspecies variation [IAV]) was introduced (0.5 for humans). Using these data, we computed that 13.100 J/m 2 of UVB radiation emitted by FS40 lamps would suppress 50% of the proliferative response of lymphocytes to L. monocytogenes in most sensitive skin type 2 humans. In step 3, we assumed the action spectrum for the responses analyzed by us as identical to an action spectrum for suppression of contact hypersensitivity that is available in the literature. In step 4, we calculated that approximately 100 min of solar exposure at around noon in Italy or Spain would suppress the resistance to infections by L. monocytogenes in the most sensitive humans. (author)

  16. Risk assessment of UVB effects on resistance to infectious diseases

    Energy Technology Data Exchange (ETDEWEB)

    Garssen, J.; Goettsch, W.; Slob, W.; Loveren, H. van [National Institute of Public Health and Environment, Bilthoven (Netherlands); de Gruijl, F. [Rijksuniversiteit Utrecht (Netherlands)

    1996-08-01

    The aim of this study was to develop a quantitative risk assessment of lowered resistance to infections in humans due to (solar) ultraviolet B (UVB) exposure. We followed the steps for risk assessment as defined by the U.S. National Academy of Sciences: (1) hazard identification, (2) dose-response assessment, (3) exposure assessment, and (4) risk characterization. For step 1, the suppressory effects of UVB radiation on the immune system has been reviewed, supplemented with new data, and analyzed. Experiments on UV-induced immunosuppression cannot be performed with humans for ethical reasons, but herpes simplex virus infection appears to be the human paradigm. Thus, UVB radiation appears to be a potential hazard to immunologic functions. Step 2 is crucial, but dose-response relationships for infections have never been measured in humans. We used our earlier dose-response rat data for suppression of lymphocyte stimulation and computed that the UVB dose resulting in a 50% reduction of lymphocyte stimulation by Listeria monocytogenes is 6.800 J/m{sup 2}. Using mixed skin lymphocyte response assays we found that humans are 3.8 times less sensitive than rats (interspecies variation [IEV]). To account for the 2.5 percentile of most susceptible individuals in a population, an additional factor (intraspecies variation [IAV]) was introduced (0.5 for humans). Using these data, we computed that 13.100 J/m{sup 2} of UVB radiation emitted by FS40 lamps would suppress 50% of the proliferative response of lymphocytes to L. monocytogenes in most sensitive skin type 2 humans. In step 3, we assumed the action spectrum for the responses analyzed by us as identical to an action spectrum for suppression of contact hypersensitivity that is available in the literature. In step 4, we calculated that approximately 100 min of solar exposure at around noon in Italy or Spain would suppress the resistance to infections by L. monocytogenes in the most sensitive humans. (author).

  17. The effect of resistance exercise on sleep: A systematic review of randomized controlled trials.

    Science.gov (United States)

    Kovacevic, Ana; Mavros, Yorgi; Heisz, Jennifer J; Fiatarone Singh, Maria A

    2018-06-01

    Impaired sleep quality and quantity are associated with future morbidity and mortality. Exercise may be an effective non-pharmacological intervention to improve sleep, however, little is known on the effect of resistance exercise. Thus, we performed a systematic review of the literature to determine the acute and chronic effects of resistance exercise on sleep quantity and quality. Thirteen studies were included. Chronic resistance exercise improves all aspects of sleep, with the greatest benefit for sleep quality. These benefits of isolated resistance exercise are attenuated when resistance exercise is combined with aerobic exercise and compared to aerobic exercise alone. However, the acute effects of resistance exercise on sleep remain poorly studied and inconsistent. In addition to the sleep benefits, resistance exercise training improves anxiety and depression. These results suggest that resistance exercise may be an effective intervention to improve sleep quality. Further research is needed to better understand the effects of acute resistance exercise on sleep, the physiological mechanisms underlying changes in sleep, the changes in sleep architecture with chronic resistance exercise, as well its efficacy in clinical cohorts who commonly experience sleep disturbance. Future studies should also examine time-of-day and dose-response effects to determine the optimal exercise prescription for sleep benefits. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Characterization of resistance to tetracyclines and aminoglycosides of sheep mastitis pathogens: study of the effect of gene content on resistance.

    Science.gov (United States)

    Lollai, S A; Ziccheddu, M; Duprè, I; Piras, D

    2016-10-01

    Mastitis causes economic losses and antimicrobials are frequently used for mastitis treatment. Antimicrobial resistance surveys are still rare in the ovine field and characterization of strains is important in order to acquire information about resistance and for optimization of therapy. Bacterial pathogens recovered in milk samples from mastitis-affected ewes were characterized for resistance to tetracyclines and aminoglycosides, members of which are frequently used antimicrobials in small ruminants. A total of 185 strains of staphylococci, streptococci, and enterococci, common mastitis pathogens, were tested for minimal inhibitory concentration (MIC) to tetracycline, doxycycline, minocycline, gentamicin, kanamycin, streptomycin, and for resistance genes by PCR. Effects of different tet genes arrangements on MICs were also investigated. Staphylococci expressed the lowest MIC for tetracycline and tet(K) was the most common gene recovered; tet(M) and tet(O) were also found. Gene content was shown to influence the tetracycline MIC values. Enterococci and streptococci showed higher MICs to tetracyclines and nonsusceptible strains always harboured at least one ribosomal protection gene (MIC above 8 μg ml(-1) ). Streptococci often harboured two or more tet determinants. As regards the resistance to aminoglycosides, staphylococci showed the lowest gentamicin and kanamycin median MIC along with streptomycin high level resistant (HLR) strains (MIC >1024 μg ml(-1) ) all harbouring str gene. The resistance determinant aac(6')-Ie-aph(2″)-Ia was present in few strains. Streptococci were basically nonsusceptible to aminoglycosides but neither HLR isolates nor resistance genes were detected. Enterococci revealed the highest MICs for gentamicin; two str harbouring isolates were shown to be HLR to streptomycin. Evidence was obtained for the circulation of antimicrobial-resistant strains and genes in sheep dairy farming. Tetracycline MIC of 64 μg ml(-1) and high

  19. Effective dominance of resistance of Spodoptera frugiperda to Bt maize and cotton varieties: implications for resistance management

    Science.gov (United States)

    Horikoshi, Renato J.; Bernardi, Daniel; Bernardi, Oderlei; Malaquias, José B.; Okuma, Daniela M.; Miraldo, Leonardo L.; Amaral, Fernando S. De A. E.; Omoto, Celso

    2016-10-01

    The resistance of fall armyworm (FAW), Spodoptera frugiperda, has been characterized to some Cry and Vip3A proteins of Bacillus thuringiensis (Bt) expressed in transgenic maize in Brazil. Here we evaluated the effective dominance of resistance based on the survival of neonates from selected Bt-resistant, heterozygous, and susceptible (Sus) strains of FAW on different Bt maize and cotton varieties. High survival of strains resistant to the Cry1F (HX-R), Cry1A.105/Cry2Ab (VT-R) and Cry1A.105/Cry2Ab/Cry1F (PW-R) proteins was detected on Herculex, YieldGard VT PRO and PowerCore maize. Our Vip3A-resistant strain (Vip-R) exhibited high survival on Herculex, Agrisure Viptera and Agrisure Viptera 3 maize. However, the heterozygous from HX-R × Sus, VT-R × Sus, PW-R × Sus and Vip-R × Sus had complete mortality on YieldGard VT PRO, PowerCore, Agrisure Viptera, and Agrisure Viptera 3, whereas the HX-R × Sus and Vip-R × Sus strains survived on Herculex maize. On Bt cotton, the HX-R, VT-R and PW-R strains exhibited high survival on Bollgard II. All resistant strains survived on WideStrike, but only PW-R and Vip-R × Sus survived on TwinLink. Our study provides useful data to aid in the understanding of the effectiveness of the refuge strategy for Insect Resistance Management of Bt plants.

  20. Scalar-metric and scalar-metric-torsion gravitational theories

    International Nuclear Information System (INIS)

    Aldersley, S.J.

    1977-01-01

    The techniques of dimensional analysis and of the theory of tensorial concomitants are employed to study field equations in gravitational theories which incorporate scalar fields of the Brans-Dicke type. Within the context of scalar-metric gravitational theories, a uniqueness theorem for the geometric (or gravitational) part of the field equations is proven and a Lagrangian is determined which is uniquely specified by dimensional analysis. Within the context of scalar-metric-torsion gravitational theories a uniqueness theorem for field Lagrangians is presented and the corresponding Euler-Lagrange equations are given. Finally, an example of a scalar-metric-torsion theory is presented which is similar in many respects to the Brans-Dicke theory and the Einstein-Cartan theory

  1. Effects of Weight Resistance Training on Swimmers with Down Syndrome

    Directory of Open Access Journals (Sweden)

    Fabián Víquez Ulate y Andrea Mora Campos

    2011-01-01

    Full Text Available The objective of this study was to determine the effect of weight resistance training on strength in swimmers with Down Syndrome (DS. Seven swimmers with DS participated in the study: 6 men and 1 woman, 23.14 years of age ± 4.59 and with 6.14 years ± 2.34 years of swimming. Instruments: One repetition maximum (RM test to determine the individual’s maximum muscular strength. Procedure: the study was conducted for 10 weeks (2 weeks at baseline, 6 weeks of treatment and 2 weeks to see the effects of retention. Results: significantly positive changes were detected in the maximum strength of pectoral muscles (F=5.768; p=0.006, dorsal muscles (F = 26.770; p=7.45e-007, femoral biceps (F = 32.530; p=1.76e-007, quadriceps (F = 8.391; p=0.001, triceps (F = 11.217; p=0.0002 and these adjustments were maintained with no significant changes for two weeks, while the biceps muscle (F=4.145; p=0.021 behaved differently since it suffered no significant adjustments during the program.

  2. Radiation Resistant Hybrid Lotus Effect Photoelectrocatalytic Self-Cleaning Anti-Contamination Coatings, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This project will develop radiation resistant hybrid Lotus Effect photoelectrocatalytic self-cleaning anti-contamination coatings for application to Lunar...

  3. Effects of UV light disinfection on antibiotic-resistant coliforms in wastewater effluents

    International Nuclear Information System (INIS)

    Meckes, M.C.

    1982-01-01

    Total coliforms and total coliforms resistant to streptomycin, tetracycline, or chloramphenicol were isolated from filtered activated sludge effluents before and after UV light irradiation. Although the UV irradiation effectively disinfected the wastewater effluent, the percentage of the total surviving coliform population resistant to tetracycline or chloramphenicol was significantly higher than the percentage of the total coliform population resistant to those antibiotics before UV irradiation. This finding was attributed to the mechanism of R-factor mediated resistance to tetracycline. No significant difference was noted for the percentage of the surviving total coliform population resistant to streptomycin before or after UV irradiation. Multiple drug resistant to patterns of 300 total coliform isolates revealed that 82% were resistant to two or more antibiotics. Furthermore, 46% of these isolates were capable of transferring antibiotic resistance to a sensitive strain of Escherichia coli

  4. Effect of composition on the polarization and ohmic resistances of ...

    Indian Academy of Sciences (India)

    2017-06-09

    Jun 9, 2017 ... Solid oxide fuel cell; composite cathodes; polarization resistance; ohmic resistance; ... of Oad on LSM, (iii) conversion of Oad into oxygen ion ... ions need to flow through the low temperature sintered ..... TPB's are present) suggest the formation of face-to-face con- ..... calculated using the following equation.

  5. Effect of biocides on biofilms of some multidrug resistant clinical ...

    African Journals Online (AJOL)

    The ability of Escherichia coli and Klebsiella aerogenes to form biofilms was most affected. There was little inhibition of biofilm formation by the biocides on Staphylococcus aureus. This study has shown a relationship between biocide and multidrug resistance. Keywords: Biocides, Multi drug resistance, sodium hypochlorite, ...

  6. Resistance to Change among Veteran Teachers: Providing Voice for More Effective Engagement

    Science.gov (United States)

    Snyder, Richard R.

    2017-01-01

    Effective implementation of change remains a crucial concern for educational leaders in the 21st Century. One of the factors affecting effective implementation of reform is resistance to change. Veteran teachers in particular present unique challenges, and stereotypically the greatest resistance, for effective implementation of change. This study…

  7. Regge calculus from discontinuous metrics

    International Nuclear Information System (INIS)

    Khatsymovsky, V.M.

    2003-01-01

    Regge calculus is considered as a particular case of the more general system where the linklengths of any two neighbouring 4-tetrahedra do not necessarily coincide on their common face. This system is treated as that one described by metric discontinuous on the faces. In the superspace of all discontinuous metrics the Regge calculus metrics form some hypersurface defined by continuity conditions. Quantum theory of the discontinuous metric system is assumed to be fixed somehow in the form of quantum measure on (the space of functionals on) the superspace. The problem of reducing this measure to the Regge hypersurface is addressed. The quantum Regge calculus measure is defined from a discontinuous metric measure by inserting the δ-function-like phase factor. The requirement that continuity conditions be imposed in a 'face-independent' way fixes this factor uniquely. The term 'face-independent' means that this factor depends only on the (hyper)plane spanned by the face, not on it's form and size. This requirement seems to be natural from the viewpoint of existence of the well-defined continuum limit maximally free of lattice artefacts

  8. The correlation of metrics in complex networks with applications in functional brain networks

    International Nuclear Information System (INIS)

    Li, C; Wang, H; Van Mieghem, P; De Haan, W; Stam, C J

    2011-01-01

    An increasing number of network metrics have been applied in network analysis. If metric relations were known better, we could more effectively characterize networks by a small set of metrics to discover the association between network properties/metrics and network functioning. In this paper, we investigate the linear correlation coefficients between widely studied network metrics in three network models (Bárabasi–Albert graphs, Erdös–Rényi random graphs and Watts–Strogatz small-world graphs) as well as in functional brain networks of healthy subjects. The metric correlations, which we have observed and theoretically explained, motivate us to propose a small representative set of metrics by including only one metric from each subset of mutually strongly dependent metrics. The following contributions are considered important. (a) A network with a given degree distribution can indeed be characterized by a small representative set of metrics. (b) Unweighted networks, which are obtained from weighted functional brain networks with a fixed threshold, and Erdös–Rényi random graphs follow a similar degree distribution. Moreover, their metric correlations and the resultant representative metrics are similar as well. This verifies the influence of degree distribution on metric correlations. (c) Most metric correlations can be explained analytically. (d) Interestingly, the most studied metrics so far, the average shortest path length and the clustering coefficient, are strongly correlated and, thus, redundant. Whereas spectral metrics, though only studied recently in the context of complex networks, seem to be essential in network characterizations. This representative set of metrics tends to both sufficiently and effectively characterize networks with a given degree distribution. In the study of a specific network, however, we have to at least consider the representative set so that important network properties will not be neglected

  9. Symmetries of Taub-NUT dual metrics

    International Nuclear Information System (INIS)

    Baleanu, D.; Codoban, S.

    1998-01-01

    Recently geometric duality was analyzed for a metric which admits Killing tensors. An interesting example arises when the manifold has Killing-Yano tensors. The symmetries of the dual metrics in the case of Taub-NUT metric are investigated. Generic and non-generic symmetries of dual Taub-NUT metric are analyzed

  10. Effects of Oxidation on Oxidation-Resistant Graphite

    Energy Technology Data Exchange (ETDEWEB)

    Windes, William [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, Rebecca [Idaho National Lab. (INL), Idaho Falls, ID (United States); Carroll, Mark [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-05-01

    The Advanced Reactor Technology (ART) Graphite Research and Development Program is investigating doped nuclear graphite grades that exhibit oxidation resistance through the formation of protective oxides on the surface of the graphite material. In the unlikely event of an oxygen ingress accident, graphite components within the VHTR core region are anticipated to oxidize so long as the oxygen continues to enter the hot core region and the core temperatures remain above 400°C. For the most serious air-ingress accident which persists over several hours or days the continued oxidation can result in significant structural damage to the core. Reducing the oxidation rate of the graphite core material during any air-ingress accident would mitigate the structural effects and keep the core intact. Previous air oxidation testing of nuclear-grade graphite doped with varying levels of boron-carbide (B4C) at a nominal 739°C was conducted for a limited number of doped specimens demonstrating a dramatic reduction in oxidation rate for the boronated graphite grade. This report summarizes the conclusions from this small scoping study by determining the effects of oxidation on the mechanical strength resulting from oxidation of boronated and unboronated graphite to a 10% mass loss level. While the B4C additive did reduce mechanical strength loss during oxidation, adding B4C dopants to a level of 3.5% or more reduced the as-fabricated compressive strength nearly 50%. This effectively minimized any benefits realized from the protective film formed on the boronated grades. Future work to infuse different graphite grades with silicon- and boron-doped material as a post-machining conditioning step for nuclear components is discussed as a potential solution for these challenges in this report.

  11. A Kerr-NUT metric

    International Nuclear Information System (INIS)

    Vaidya, P.C.; Patel, L.K.; Bhatt, P.V.

    1976-01-01

    Using Galilean time and retarded distance as coordinates the usual Kerr metric is expressed in form similar to the Newman-Unti-Tamburino (NUT) metric. The combined Kerr-NUT metric is then investigated. In addition to the Kerr and NUT solutions of Einstein's equations, three other types of solutions are derived. These are (i) the radiating Kerr solution, (ii) the radiating NUT solution satisfying Rsub(ik) = sigmaxisub(i)xisub(k), xisub(i)xisup(i) = 0, and (iii) the associated Kerr solution satisfying Rsub(ik) = 0. Solution (i) is distinct from and simpler than the one reported earlier by Vaidya and Patel (Phys. Rev.; D7:3590 (1973)). Solutions (ii) and (iii) gave line elements which have the axis of symmetry as a singular line. (author)

  12. Complexity Metrics for Workflow Nets

    DEFF Research Database (Denmark)

    Lassen, Kristian Bisgaard; van der Aalst, Wil M.P.

    2009-01-01

    analysts have difficulties grasping the dynamics implied by a process model. Recent empirical studies show that people make numerous errors when modeling complex business processes, e.g., about 20 percent of the EPCs in the SAP reference model have design flaws resulting in potential deadlocks, livelocks......, etc. It seems obvious that the complexity of the model contributes to design errors and a lack of understanding. It is not easy to measure complexity, however. This paper presents three complexity metrics that have been implemented in the process analysis tool ProM. The metrics are defined...... for a subclass of Petri nets named Workflow nets, but the results can easily be applied to other languages. To demonstrate the applicability of these metrics, we have applied our approach and tool to 262 relatively complex Protos models made in the context of various student projects. This allows us to validate...

  13. Predicting date rape perceptions: the effects of gender, gender role attitudes, and victim resistance.

    Science.gov (United States)

    Black, Katherine A; McCloskey, Kathy A

    2013-08-01

    The effects of participant gender and victim resistance on date rape perceptions have been inconsistent. Participant gender role attitudes may contribute to these inconsistencies. We found women with traditional gender role attitudes were least likely to agree that the perpetrator was guilty of rape. Participants were less convinced of the perpetrator's guilt when the victim resisted verbally than when she resisted verbally and physically, and participants with traditional gender role attitudes were less convinced of the negative impact on the victim when she resisted verbally than when she resisted verbally and physically. Perhaps previous inconsistencies resulted from varying proportions of men and women with traditional versus liberal gender role attitudes in the samples.

  14. INFORMATIVE ENERGY METRIC FOR SIMILARITY MEASURE IN REPRODUCING KERNEL HILBERT SPACES

    Directory of Open Access Journals (Sweden)

    Songhua Liu

    2012-02-01

    Full Text Available In this paper, information energy metric (IEM is obtained by similarity computing for high-dimensional samples in a reproducing kernel Hilbert space (RKHS. Firstly, similar/dissimilar subsets and their corresponding informative energy functions are defined. Secondly, IEM is proposed for similarity measure of those subsets, which converts the non-metric distances into metric ones. Finally, applications of this metric is introduced, such as classification problems. Experimental results validate the effectiveness of the proposed method.

  15. In Vitro Antibacterial and Antibiotic Resistance Modifying Effect of Bioactive Plant Extracts on Methicillin-Resistant Staphylococcus epidermidis

    Directory of Open Access Journals (Sweden)

    Romana Chovanová

    2013-01-01

    Full Text Available The crude extracts of plants from Asteraceae and Lamiaceae family and essential oils from Salvia officinalis and Salvia sclarea were studied for their antibacterial as well as antibiotic resistance modifying activity. Using disc diffusion and broth microdilution assays we determined higher antibacterial effect of three Salvia spp. and by evaluating the leakage of 260 nm absorbing material we detected effect of extracts and, namely, of essential oils on the disruption of cytoplasmic membrane. The evaluation of in vitro interactions between plant extracts and oxacillin described in terms of fractional inhibitory concentration (FIC indices revealed synergistic or additive effects of plant extracts and clearly synergistic effects of essential oil from Salvia officinalis with oxacillin in methicillin-resistant Staphylococcus epidermidis.

  16. Beyond Lovelock gravity: Higher derivative metric theories

    Science.gov (United States)

    Crisostomi, M.; Noui, K.; Charmousis, C.; Langlois, D.

    2018-02-01

    We consider theories describing the dynamics of a four-dimensional metric, whose Lagrangian is diffeomorphism invariant and depends at most on second derivatives of the metric. Imposing degeneracy conditions we find a set of Lagrangians that, apart form the Einstein-Hilbert one, are either trivial or contain more than 2 degrees of freedom. Among the partially degenerate theories, we recover Chern-Simons gravity, endowed with constraints whose structure suggests the presence of instabilities. Then, we enlarge the class of parity violating theories of gravity by introducing new "chiral scalar-tensor theories." Although they all raise the same concern as Chern-Simons gravity, they can nevertheless make sense as low energy effective field theories or, by restricting them to the unitary gauge (where the scalar field is uniform), as Lorentz breaking theories with a parity violating sector.

  17. Effect of grain boundary microcracks on crack resistance of annealed tungsten

    International Nuclear Information System (INIS)

    Babak, A.V.; Uskov, E.I.

    1984-01-01

    Effect of grain boundary microcracks in tungsten, produced by the method of powder sintering, on its crack resistance after annealing at T=2200 deg C, has been considered. On the basis of complex physncomechanical study of tungsten crack resistance it is shown, that the value of ultimate tensile stress does not depend on temperature. The presence of grain boundary cracks in such material (in the limits from 2 to 8%) does not produce effect on its crack resistance

  18. The uniqueness of the Fisher metric as information metric

    Czech Academy of Sciences Publication Activity Database

    Le, Hong-Van

    2017-01-01

    Roč. 69, č. 4 (2017), s. 879-896 ISSN 0020-3157 Institutional support: RVO:67985840 Keywords : Chentsov’s theorem * mixed topology * monotonicity of the Fisher metric Subject RIV: BA - General Mathematics OBOR OECD: Pure mathematics Impact factor: 1.049, year: 2016 https://link.springer.com/article/10.1007%2Fs10463-016-0562-0

  19. Effect of fractons and magnons in dilute ferromagnets on resistivity

    International Nuclear Information System (INIS)

    Li Jianxin; Jiang Qing; Tian Decheng

    1993-01-01

    Based on the s - d exchange model, we investigate the temperature-dependent resistivity arising from the scattering of electrons off fractons and magnons in dilute Heisenberg ferromagnets on three-dimensional bond percolation network. The results indicate that the contribution of fracton scatterings to the resistivity varies from T 3 / 2 to T 2 dependence as the concentration of bonds approaches the percolation threshold, while the magnon scattering contributes a resistivity varying as T 3 / 2 regardless of the changes in concentration of bonds. (author). 21 refs, 4 figs

  20. Scale-dependent effects of land cover on water physico-chemistry and diatom-based metrics in a major river system, the Adour-Garonne basin (South Western France)

    International Nuclear Information System (INIS)

    Tudesque, Loïc; Tisseuil, Clément; Lek, Sovan

    2014-01-01

    The scale dependence of ecological phenomena remains a central issue in ecology. Particularly in aquatic ecology, the consideration of the accurate spatial scale in assessing the effects of landscape factors on stream condition is critical. In this context, our study aimed at assessing the relationships between multi-spatial scale land cover patterns and a variety of water quality and diatom metrics measured at the stream reach level. This investigation was conducted in a major European river system, the Adour-Garonne river basin, characterized by a wide range of ecological conditions. Redundancy analysis (RDA) and variance partitioning techniques were used to disentangle the different relationships between land cover, water-chemistry and diatom metrics. Our results revealed a top-down “cascade effect” indirectly linking diatom metrics to land cover patterns through water physico-chemistry, which occurred at the largest spatial scales. In general, the strength of the relationships between land cover, physico-chemistry, and diatoms was shown to increase with the spatial scale, from the local to the basin scale, emphasizing the importance of continuous processes of accumulation throughout the river gradient. Unexpectedly, we established that the influence of land cover on the diatom metric was of primary importance both at the basin and local scale, as a result of discontinuous but not necessarily antagonist processes. The most detailed spatial grain of the Corine land cover classification appeared as the most relevant spatial grain to relate land cover to water chemistry and diatoms. Our findings provide suitable information to improve the implementation of effective diatom-based monitoring programs, especially within the scope of the European Water Framework Directive. - Highlights: •The spatial scale dependence of the “cascade effect” in a river system has been demonstrated. •The strength of the relationships between land cover and diatoms through

  1. Thermodynamic metrics and optimal paths.

    Science.gov (United States)

    Sivak, David A; Crooks, Gavin E

    2012-05-11

    A fundamental problem in modern thermodynamics is how a molecular-scale machine performs useful work, while operating away from thermal equilibrium without excessive dissipation. To this end, we derive a friction tensor that induces a Riemannian manifold on the space of thermodynamic states. Within the linear-response regime, this metric structure controls the dissipation of finite-time transformations, and bestows optimal protocols with many useful properties. We discuss the connection to the existing thermodynamic length formalism, and demonstrate the utility of this metric by solving for optimal control parameter protocols in a simple nonequilibrium model.

  2. Invariant metrics for Hamiltonian systems

    International Nuclear Information System (INIS)

    Rangarajan, G.; Dragt, A.J.; Neri, F.

    1991-05-01

    In this paper, invariant metrics are constructed for Hamiltonian systems. These metrics give rise to norms on the space of homeogeneous polynomials of phase-space variables. For an accelerator lattice described by a Hamiltonian, these norms characterize the nonlinear content of the lattice. Therefore, the performance of the lattice can be improved by minimizing the norm as a function of parameters describing the beam-line elements in the lattice. A four-fold increase in the dynamic aperture of a model FODO cell is obtained using this procedure. 7 refs

  3. Generalization of Vaidya's radiation metric

    Energy Technology Data Exchange (ETDEWEB)

    Gleiser, R J; Kozameh, C N [Universidad Nacional de Cordoba (Argentina). Instituto de Matematica, Astronomia y Fisica

    1981-11-01

    In this paper it is shown that if Vaidya's radiation metric is considered from the point of view of kinetic theory in general relativity, the corresponding phase space distribution function can be generalized in a particular way. The new family of spherically symmetric radiation metrics obtained contains Vaidya's as a limiting situation. The Einstein field equations are solved in a ''comoving'' coordinate system. Two arbitrary functions of a single variable are introduced in the process of solving these equations. Particular examples considered are a stationary solution, a nonvacuum solution depending on a single parameter, and several limiting situations.

  4. Residential Energy Performance Metrics

    Directory of Open Access Journals (Sweden)

    Christopher Wright

    2010-06-01

    Full Text Available Techniques for residential energy monitoring are an emerging field that is currently drawing significant attention. This paper is a description of the current efforts to monitor and compare the performance of three solar powered homes built at Missouri University of Science and Technology. The homes are outfitted with an array of sensors and a data logger system to measure and record electricity production, system energy use, internal home temperature and humidity, hot water production, and exterior ambient conditions the houses are experiencing. Data is being collected to measure the performance of the houses, compare to energy modeling programs, design and develop cost effective sensor systems for energy monitoring, and produce a cost effective home control system.

  5. Technical Privacy Metrics: a Systematic Survey

    OpenAIRE

    Wagner, Isabel; Eckhoff, David

    2018-01-01

    The file attached to this record is the author's final peer reviewed version The goal of privacy metrics is to measure the degree of privacy enjoyed by users in a system and the amount of protection offered by privacy-enhancing technologies. In this way, privacy metrics contribute to improving user privacy in the digital world. The diversity and complexity of privacy metrics in the literature makes an informed choice of metrics challenging. As a result, instead of using existing metrics, n...

  6. Remarks on G-Metric Spaces

    Directory of Open Access Journals (Sweden)

    Bessem Samet

    2013-01-01

    Full Text Available In 2005, Mustafa and Sims (2006 introduced and studied a new class of generalized metric spaces, which are called G-metric spaces, as a generalization of metric spaces. We establish some useful propositions to show that many fixed point theorems on (nonsymmetric G-metric spaces given recently by many authors follow directly from well-known theorems on metric spaces. Our technique can be easily extended to other results as shown in application.

  7. DLA Energy Biofuel Feedstock Metrics Study

    Science.gov (United States)

    2012-12-11

    moderately/highly in- vasive  Metric 2: Genetically modified organism ( GMO ) hazard, Yes/No and Hazard Category  Metric 3: Species hybridization...4– biofuel distribution Stage # 5– biofuel use Metric 1: State inva- siveness ranking Yes Minimal Minimal No No Metric 2: GMO hazard Yes...may utilize GMO microbial or microalgae species across the applicable biofuel life cycles (stages 1–3). The following consequence Metrics 4–6 then

  8. Resistive-wall Wake Effect in the Beam Delivery System

    International Nuclear Information System (INIS)

    Delayen, J.R.; Jefferson Lab; Wu, Juhao; Raubenheimer, T.O.; SLAC; Wang, Jiunn-Ming; BNL, NSLS

    2005-01-01

    General formulae for resistive-wall induced beam dilution are presented and then applied to the final beam delivery system of linear colliders. Criteria for the design of final beam delivery systems are discussed

  9. Economic Metrics for Commercial Reusable Space Transportation Systems

    Science.gov (United States)

    Shaw, Eric J.; Hamaker, Joseph (Technical Monitor)

    2000-01-01

    The success of any effort depends upon the effective initial definition of its purpose, in terms of the needs to be satisfied and the goals to be fulfilled. If the desired product is "A System" that is well-characterized, these high-level need and goal statements can be transformed into system requirements by traditional systems engineering techniques. The satisfaction of well-designed requirements can be tracked by fairly straightforward cost, schedule, and technical performance metrics. Unfortunately, some types of efforts, including those that NASA terms "Programs," tend to resist application of traditional systems engineering practices. In the NASA hierarchy of efforts, a "Program" is often an ongoing effort with broad, high-level goals and objectives. A NASA "project" is a finite effort, in terms of budget and schedule, that usually produces or involves one System. Programs usually contain more than one project and thus more than one System. Special care must be taken in the formulation of NASA Programs and their projects, to ensure that lower-level project requirements are traceable to top-level Program goals, feasible with the given cost and schedule constraints, and measurable against top-level goals. NASA Programs and projects are tasked to identify the advancement of technology as an explicit goal, which introduces more complicating factors. The justification for funding of technology development may be based on the technology's applicability to more than one System, Systems outside that Program or even external to NASA. Application of systems engineering to broad-based technology development, leading to effective measurement of the benefits, can be valid, but it requires that potential beneficiary Systems be organized into a hierarchical structure, creating a "system of Systems." In addition, these Systems evolve with the successful application of the technology, which creates the necessity for evolution of the benefit metrics to reflect the changing

  10. Separable metrics and radiating stars

    Indian Academy of Sciences (India)

    We study the junction condition relating the pressure to heat flux at the boundary of an accelerating and expanding spherically symmetric radiating star. We transform the junction condition to an ordinary differential equation by making a separability assumption on the metric functions in the space–time variables.

  11. Socio-technical security metrics

    NARCIS (Netherlands)

    Gollmann, D.; Herley, C.; Koenig, V.; Pieters, W.; Sasse, M.A.

    2015-01-01

    Report from Dagstuhl seminar 14491. This report documents the program and the outcomes of Dagstuhl Seminar 14491 “Socio-Technical Security Metrics”. In the domain of safety, metrics inform many decisions, from the height of new dikes to the design of nuclear plants. We can state, for example, that

  12. Investigation of the integrated effects of irradiating platinum resistance thermometers

    International Nuclear Information System (INIS)

    Neverov, V.A.; Revyakin, Yu.L.

    1993-01-01

    The development of nuclear energy imposes increased demands on the reliability and quality of the information obtained from primary transducers which monitor the basic parameters of current reactor devices. One of these parameters is the temperature of different modules. This is mainly measured by thermoelectric transducers. Resistance thermometers now being adopted into measurement practice. These provide an initial accuracy of better than plus or minus 273 degrees C and also a normalized systematic error component caused by the action of the temperature. However, a systematic error component resulting from the action of the reactor radiation remains undetermined, and this greatly hinders the extensive use of resistance thermometers in reactor devices. Investigations were made using platinum resistance thermometers of different constructions designs. Irradiation took place in sealed ampules. Each of these contained three thermometers. The fluence achieved was varied by placing the ampules at different heights relative to the central plane of the active zone of the reactor. The irradiation temperature was determined by calculation, taking into account the radiative energy release where the irradiation occurred and the helium gap between the thermometer casing and the walls of an SM-2 reactor channel. Following irradiation in the reactor, the resistance thermometers were calibrated in a special thermometric device providing the minimum contact resistance, uniform heating of the samples, and stabilization of the temperature regime

  13. Combined effects of fretting and pollutant particles on the contact resistance of the electrical connectors

    Directory of Open Access Journals (Sweden)

    Zhigang Kong

    2017-06-01

    Full Text Available Usually, when electrical connectors operate in vibration environments, fretting will be produced at the contact interfaces. In addition, serious environmental pollution particles will affect contact resistance of the connectors. The fretting will worsen the reliability of connectors with the pollutant particles. The combined effects of fretting and quartz particles on the contact resistance of the gold plating connectors are studied with a fretting test system. The results show that the frequencies have obvious effect on the contact resistance. The higher the frequency, the higher the contact resistance is. The quartz particles cause serious wear of gold plating, which make the nickel and copper layer exposed quickly to increase the contact resistance. Especially in high humidity environments, water supply certain adhesion function and make quartz particles easy to insert or cover the contact surfaces, and even cause opening resistance.

  14. Effect of resistance feedback on spin torque-induced switching of nanomagnets

    International Nuclear Information System (INIS)

    Garzon, Samir; Webb, Richard A.; Covington, Mark; Kaka, Shehzaad; Crawford, Thomas M.

    2009-01-01

    In large magnetoresistance devices spin torque-induced changes in resistance can produce GHz current and voltage oscillations which can affect magnetization reversal. In addition, capacitive shunting in large resistance devices can further reduce the current, adversely affecting spin torque switching. Here, we simultaneously solve the Landau-Lifshitz-Gilbert equation with spin torque and the transmission line telegrapher's equations to study the effects of resistance feedback and capacitance on magnetization reversal of both spin valves and magnetic tunnel junctions. While for spin valves parallel (P) to anti-parallel (AP) switching is adversely affected by the resistance feedback due to saturation of the spin torque, in low resistance magnetic tunnel junctions P-AP switching is enhanced. We study the effect of resistance feedback on the switching time of magnetic tunnel junctions, and show that magnetization switching is only affected by capacitive shunting in the pF range.

  15. The effect of energetic trapped particles on the resistive internal Kink

    International Nuclear Information System (INIS)

    Romanelli, F.; White, R.B.

    1988-01-01

    The effect of energetic trapped particles on the ideal and resistive internal Kink mode is analyzed including diamagnetic effects. The relation between different approaches to the problem is discussed

  16. Social Media Metrics Importance and Usage Frequency in Latvia

    OpenAIRE

    Ronalds Skulme

    2017-01-01

    Purpose of the article: The purpose of this paper was to explore which social media marketing metrics are most often used and are most important for marketing experts in Latvia and can be used to evaluate marketing campaign effectiveness. Methodology/methods: In order to achieve the aim of this paper several theoretical and practical research methods were used, such as theoretical literature analysis, surveying and grouping. First of all, theoretical research about social media metrics was...

  17. Second order elastic metrics on the shape space of curves

    DEFF Research Database (Denmark)

    Bauer, Martin; Bruveris, Martins; Harms, Philipp

    2015-01-01

    Second order Sobolev metrics on the space of regular unparametrized planar curves have several desirable completeness properties not present in lower order metrics, but numerics are still largely missing. In this paper, we present algorithms to numerically solve the initial and boundary value......, due to its generality, it could be applied to more general spaces of mapping. We demonstrate the effectiveness of our approach by analyzing a collection of shapes representing physical objects....

  18. Resources available for applying metrics in security and safety programming.

    Science.gov (United States)

    Luizzo, Anthony

    2016-01-01

    Incorporating metrics into security surveys has been championed as a better way of substantiating program-related effectiveness and expenditures. Although security surveys have been aroundfor well over 40 years, rarely, if ever, have metric-related strategies been part of the equation, the author says. In this article, he cites several published articles and research findings available to security professionals and their surveyors that may give them the expertise and confidence they need to make use of this valuable tool.

  19. Effect of tempering on corrosion resistance of cast aluminium bronzes

    International Nuclear Information System (INIS)

    Aaltonen, P.; Klemetti, K.; Haenninen, H.

    1985-01-01

    The subject of this study is corrosion resistance of aluminium bronzes, which are copper base alloys containing aluminium up to 12% with additions of nickel, iron and manganese. The main conclutions that can be drawn are: (1) The dealloying corrosion resistance of nickel-aluminium bronze is much better than that of aluminium bronze with iron and manganese additions, but it is not immune; (2) The dealloying corrosion resistance of aluminium bronzes can be improved by appropiate heat treatments. The best properties were obtained by temperering between 600 and 800 deg C, depending on the initial microstructure; (3) In crevice conditions, where local acidification can occur, dealloying of aluminium bronzes is a consequence of the preferential attack of aluminium-rich phases. By appropriate tempering, a uniform distribution of aluminium-rich phases is obtained and the continous path for selective corrosion is not formed

  20. The Effect of Oxygen on Bile Resistance in Listeria monocytogenes

    Science.gov (United States)

    Wright, Morgan L; Pendarvis, Ken; Nanduri, Bindu; Edelmann, Mariola J; Jenkins, Haley N; Reddy, Joseph S; Wilson, Jessica G; Ding, Xuan; Broadway, Paul R; Ammari, Mais G; Paul, Oindrila; Roberts, Brandy; Donaldson, Janet R

    2016-01-01

    Listeria monocytogenes is a Gram-positive facultative anaerobe that is the causative agent of the disease listeriosis. The infectious ability of this bacterium is dependent upon resistance to stressors encountered within the gastrointestinal tract, including bile. Previous studies have indicated bile salt hydrolase activity increases under anaerobic conditions, suggesting anaerobic conditions influence stress responses. Therefore, the goal of this study was to determine if reduced oxygen availability increased bile resistance of L. monocytogenes. Four strains representing three serovars were evaluated for changes in viability and proteome expression following exposure to bile in aerobic or anaerobic conditions. Viability for F2365 (serovar 4b), EGD-e (serovar 1/2a), and 10403S (serovar 1/2a) increased following exposure to 10% porcine bile under anaerobic conditions (P 0.05) in bile resistance between aerobic and anaerobic conditions, indicating that oxygen availability does not influence resistance in this strain. The proteomic analysis indicated F2365 and EGD-e had an increased expression of proteins associated with cell envelope and membrane bioenergetics under anaerobic conditions, including thioredoxin-disulfide reductase and cell division proteins. Interestingly, HCC23 had an increase in several dehydrogenases following exposure to bile under aerobic conditions, suggesting that the NADH:NAD+ is altered and may impact bile resistance. Variations were observed in the expression of the cell shape proteins between strains, which corresponded to morphological differences observed by scanning electron microscopy. These data indicate that oxygen availability influences bile resistance. Further research is needed to decipher how these changes in metabolism impact pathogenicity in vivo and also the impact that this has on susceptibility of a host to listeriosis. PMID:27274623

  1. Effect of fluid-filled boreholes on resistivity tomography; Hiteiko tomography ni okeru konaisui no eikyo

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, Y [DIA Consultants Co. Ltd., Tokyo (Japan)

    1997-10-22

    Theoretical discussions were given on the effect of fluid-filled boreholes on resistivity tomography. The discussions performed incorporation of earth resistance as a method to consider borehole diameters in an FEM calculation using wire elements. The numerical experiment conducted a simulation on the following two objects: resistivity tomography in a horizontal multi-layer structure consisted of layers with resistivity ranging from 10 to 10000 ohm-m, and a model with a slanted low resistivity band existing in a background of 5000 ohm-m. As a result of the discussions, it was made clear that the effect of the boreholes can be corrected by giving earth resistance between the wire elements and natural ground. An improved potential calculating program indicated that the effect of the fluid-filled boreholes in the resistivity tomography generates false images with high resistivity along the bores if the resistivity has high contrast. Incorporating the wire elements into an inverse analysis model reduces the false images and improves the accuracy. 1 ref., 12 figs.

  2. The effect of resistance exercise on the thermic effect of food.

    Science.gov (United States)

    Denzer, Charlene M; Young, John C

    2003-09-01

    The thermic effect of food (TEF) is the increment in energy expenditure above resting metabolic rate associated with the cost of absorption and processing of food for storage. Previous studies have shown that TEF is enhanced by aerobic endurance exercise of sufficient duration and intensity. The purpose of this study was to determine if a similar effect occurs with a single bout of resistance exercise (weightlifting). VO2 was measured in 9 healthy volunteers (3 males and 6 females) for 2 hours after ingestion of a 2760 kJ (660 kcal) carbohydrate meal with and without prior completion of a resistance training regimen (2 sets of 10 repetitions of 10 different exercises). The meal caused an immediate and persistent thermic effect in both the control and the exercise trial. Mean oxygen consumption over baseline increased 20% in the control trial and 34% in the exercise trial. TEF calculated from VO2 and RER (total area under the response curve above baseline) was 73% greater in the exercise trial compared with the control trial (159 +/- 18 vs. 92 +/- 14 KJ/2 hrs, p carbohydrate meal is enhanced following a single bout of resistance exercise.

  3. Pleiotropic effects of herbicide-resistance genes on crop yield: a review.

    Science.gov (United States)

    Darmency, Henri

    2013-08-01

    The rapid adoption of genetically engineered herbicide-resistant crop varieties (HRCVs)-encompassing 83% of all GM crops and nearly 8% of the worldwide arable area-is due to technical efficiency and higher returns. Other herbicide-resistant varieties obtained from genetic resources and mutagenesis have also been successfully released. Although the benefit for weed control is the main criteria for choosing HRCVs, the pleiotropic costs of genes endowing resistance have rarely been investigated in crops. Here the available data of comparisons between isogenic resistant and susceptible varieties are reviewed. Pleiotropic harmful effects on yield are reported in half of the cases, mostly with resistance mechanisms that originate from genetic resources and mutagenesis (atrazine in oilseed rape and millet, trifluralin in millet, imazamox in cotton) rather than genetic engineering (chlorsulfuron and glufosinate in some oilseed rape varieties, glyphosate in soybean). No effect was found for sethoxydim and bromoxynil resistance. Variable minor effects were found for imazamox, chlorsulfuron, glufosinate and glyphosate resistance. The importance of the breeding plan and the genetic background on the emergence of these effects is pointed out. Breeders' efforts to produce better varieties could compensate for the yield loss, which eliminates any possibility of formulating generic conclusions on pleiotropic effects that can be applied to all resistant crops. © 2013 Society of Chemical Industry.

  4. Measuring reliability under epistemic uncertainty: Review on non-probabilistic reliability metrics

    Directory of Open Access Journals (Sweden)

    Kang Rui

    2016-06-01

    Full Text Available In this paper, a systematic review of non-probabilistic reliability metrics is conducted to assist the selection of appropriate reliability metrics to model the influence of epistemic uncertainty. Five frequently used non-probabilistic reliability metrics are critically reviewed, i.e., evidence-theory-based reliability metrics, interval-analysis-based reliability metrics, fuzzy-interval-analysis-based reliability metrics, possibility-theory-based reliability metrics (posbist reliability and uncertainty-theory-based reliability metrics (belief reliability. It is pointed out that a qualified reliability metric that is able to consider the effect of epistemic uncertainty needs to (1 compensate the conservatism in the estimations of the component-level reliability metrics caused by epistemic uncertainty, and (2 satisfy the duality axiom, otherwise it might lead to paradoxical and confusing results in engineering applications. The five commonly used non-probabilistic reliability metrics are compared in terms of these two properties, and the comparison can serve as a basis for the selection of the appropriate reliability metrics.

  5. EVALUATING THE EFFECT OF HOST PLANT RESISTANCE AND ...

    African Journals Online (AJOL)

    Prof. Adipala Ekwamu

    friendly and affordable by local resource poor farmers. Though information is available on genotypic resistance to M. vitrata in cowpea, such information on pigeon pea and other legumes AYB inclusive is limited. Considering the nutritional values of AYB, there is need to adopt measures that will control this important pest of ...

  6. Effects of Zn doping concentration on resistive switching ...

    Indian Academy of Sciences (India)

    conduction mechanism at low resistance state varies with Zn doping concentration. The dominant .... shows the evolution of RHRS and RLRS in 1000 cycles under a reading voltage of 2 V ... 0.5 exhibited poor fatigue properties. As shown in ...

  7. Effects of Behavioral History on Resistance to Change

    Science.gov (United States)

    Doughty, Adam H.; Cirino, Sergio; Mayfield, Kristin H.; da Silva, Stephanie P.; Okouchi, Hiroto; Lattal, Kennon A.

    2005-01-01

    Two experiments examined whether differential resistance to change would occur under identical variable-interval schedules as a function of a differential behavioral history. In Experiment 1, each of 3 pigeons first pecked at different rates under a multiple variable-ratio differential-reinforcement-of-low-rate schedule. In a subsequent condition,…

  8. Effects of Copper Addition on Copper Resistance, Antibiotic Resistance Genes, and intl1 during Swine Manure Composting

    Science.gov (United States)

    Yin, Yanan; Gu, Jie; Wang, Xiaojuan; Song, Wen; Zhang, Kaiyu; Sun, Wei; Zhang, Xin; Zhang, Yajun; Li, Haichao

    2017-01-01

    Copper is one of the most abundant heavy metals present in swine manure. In this study, a laboratory-scale aerobic composting system was amended with Cu at three levels (0, 200, and 2000 mg kg-1, i.e., control, Cu200, and Cu2000 treatments, respectively) to determine its effect on the fate of copper resistance genes [copper resistance genes (CRGs): pcoA, cusA, copA, and tcrB], antibiotic resistance genes [antibiotic resistance genes (ARGs): erm(A) and erm(B)], and intl1. The results showed that the absolute abundances of pcoA, tcrB, erm(A), erm(B), and intl1 were reduced, whereas those of copA and cusA increased after swine manure composting. Redundancy analysis showed that temperature significantly affected the variations in CRGs, ARGs, and intl1. The decreases in CRGs, ARGs, and intI1 were positively correlated with the exchangeable Cu levels. The bacterial community could be grouped according to the composting time under different treatments, where the high concentration of copper had a more persistent effect on the bacterial community. Network analysis determined that the co-occurrence of CRGs, ARGs, and intI1, and the bacterial community were the main contributors to the changes in CRGs, ARG, and intl1. Thus, temperature, copper, and changes in the bacterial community composition had important effects on the variations in CRGs, ARGs, and intl1 during manure composting in the presence of added copper. PMID:28316595

  9. Research on cardiovascular disease prediction based on distance metric learning

    Science.gov (United States)

    Ni, Zhuang; Liu, Kui; Kang, Guixia

    2018-04-01

    Distance metric learning algorithm has been widely applied to medical diagnosis and exhibited its strengths in classification problems. The k-nearest neighbour (KNN) is an efficient method which treats each feature equally. The large margin nearest neighbour classification (LMNN) improves the accuracy of KNN by learning a global distance metric, which did not consider the locality of data distributions. In this paper, we propose a new distance metric algorithm adopting cosine metric and LMNN named COS-SUBLMNN which takes more care about local feature of data to overcome the shortage of LMNN and improve the classification accuracy. The proposed methodology is verified on CVDs patient vector derived from real-world medical data. The Experimental results show that our method provides higher accuracy than KNN and LMNN did, which demonstrates the effectiveness of the Risk predictive model of CVDs based on COS-SUBLMNN.

  10. Effects of alloying elements on nodular and uniform corrosion resistance of zirconium-based alloys

    International Nuclear Information System (INIS)

    Abe, Katsuhiro

    1992-01-01

    The effects of alloying and impurity elements (tin, iron, chromium, nickel, niobium, tantalum, oxygen, aluminum, carbon, nitrogen, silicon, and phosphorus) on the nodular and uniform corrosion resistance of zirconium-based alloys were studied. The improving effect of iron, nickel and niobium in nodular corrosion resistance were observed. The uniform corrosion resistance was also improved by nickel, niobium and tantalum. The effects of impurity elements, nitrogen, aluminum and phosphorus were negligibly small but increasing the silicon content seemed to improve slightly the uniform corrosion resistance. Hydrogen pick-up fraction were not changed by alloying and impurity elements except nickel. Nickel addition increased remarkably hydrogen pick-up fraction. Although the composition of secondary precipitates changed with contents of alloying elements, the correlation of composition of secondary precipitates to corrosion resistance was not observed. (author)

  11. Group covariance and metrical theory

    International Nuclear Information System (INIS)

    Halpern, L.

    1983-01-01

    The a priori introduction of a Lie group of transformations into a physical theory has often proved to be useful; it usually serves to describe special simplified conditions before a general theory can be worked out. Newton's assumptions of absolute space and time are examples where the Euclidian group and translation group have been introduced. These groups were extended to the Galilei group and modified in the special theory of relativity to the Poincare group to describe physics under the given conditions covariantly in the simplest way. The criticism of the a priori character leads to the formulation of the general theory of relativity. The general metric theory does not really give preference to a particular invariance group - even the principle of equivalence can be adapted to a whole family of groups. The physical laws covariantly inserted into the metric space are however adapted to the Poincare group. 8 references

  12. General relativity: An erfc metric

    Science.gov (United States)

    Plamondon, Réjean

    2018-06-01

    This paper proposes an erfc potential to incorporate in a symmetric metric. One key feature of this model is that it relies on the existence of an intrinsic physical constant σ, a star-specific proper length that scales all its surroundings. Based thereon, the new metric is used to study the space-time geometry of a static symmetric massive object, as seen from its interior. The analytical solutions to the Einstein equation are presented, highlighting the absence of singularities and discontinuities in such a model. The geodesics are derived in their second- and first-order differential formats. Recalling the slight impact of the new model on the classical general relativity tests in the solar system, a number of facts and open problems are briefly revisited on the basis of a heuristic definition of σ. A special attention is given to gravitational collapses and non-singular black holes.

  13. Long-term effect of resistant starch on cancer risk in carriers of hereditary colorectal cancer

    DEFF Research Database (Denmark)

    Mathers, John C; Movahedi, Mohammad; Macrae, Finlay

    2012-01-01

    have been done. We assessed the effect of resistant starch on the incidence of colorectal cancer. METHODS: In the CAPP2 study, individuals with Lynch syndrome were randomly assigned in a two-by-two factorial design to receive 600 mg aspirin or aspirin placebo or 30 g resistant starch or starch placebo...

  14. Temperature and mixing effects on electrical resistivity of carbon fiber enhanced concrete

    International Nuclear Information System (INIS)

    Chang, Christiana; Song, Gangbing; Gao, Di; Mo, Y L

    2013-01-01

    In this paper, the effect of temperature and mixing procedure on the electrical resistivity of carbon fiber enhanced concrete is investigated. Different compositions of concrete containing varying concentrations of carbon fiber into normal and self-consolidating concrete (SCC) were tested under DC electrical loading over the temperature range −10 to 20 °C. The electrical resistivity of the bulk samples was calculated and compared against temperature. It was observed that there is an inverse exponential relationship between resistivity and temperature which follows the Arrhenius relationship. The bulk resistivity decreased with increasing fiber concentration, though data from SCC indicates a saturation limit beyond which electrical resistivity begins to drop. The activation energy of the bulk electrically conductive concrete was calculated and compared. While SCC exhibited the lowest observed electrical resistance, the activation energy was similar amongst SCC and surfactant enhanced concrete, both of which were lower than fiber dispersed in normal concrete. (paper)

  15. hdm: High-dimensional metrics

    OpenAIRE

    Chernozhukov, Victor; Hansen, Christian; Spindler, Martin

    2016-01-01

    In this article the package High-dimensional Metrics (\\texttt{hdm}) is introduced. It is a collection of statistical methods for estimation and quantification of uncertainty in high-dimensional approximately sparse models. It focuses on providing confidence intervals and significance testing for (possibly many) low-dimensional subcomponents of the high-dimensional parameter vector. Efficient estimators and uniformly valid confidence intervals for regression coefficients on target variables (e...

  16. Multi-Metric Sustainability Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cowlin, Shannon [National Renewable Energy Lab. (NREL), Golden, CO (United States); Heimiller, Donna [National Renewable Energy Lab. (NREL), Golden, CO (United States); Macknick, Jordan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mann, Margaret [National Renewable Energy Lab. (NREL), Golden, CO (United States); Pless, Jacquelyn [National Renewable Energy Lab. (NREL), Golden, CO (United States); Munoz, David [Colorado School of Mines, Golden, CO (United States)

    2014-12-01

    A readily accessible framework that allows for evaluating impacts and comparing tradeoffs among factors in energy policy, expansion planning, and investment decision making is lacking. Recognizing this, the Joint Institute for Strategic Energy Analysis (JISEA) funded an exploration of multi-metric sustainability analysis (MMSA) to provide energy decision makers with a means to make more comprehensive comparisons of energy technologies. The resulting MMSA tool lets decision makers simultaneously compare technologies and potential deployment locations.

  17. Sensory Metrics of Neuromechanical Trust.

    Science.gov (United States)

    Softky, William; Benford, Criscillia

    2017-09-01

    Today digital sources supply a historically unprecedented component of human sensorimotor data, the consumption of which is correlated with poorly understood maladies such as Internet addiction disorder and Internet gaming disorder. Because both natural and digital sensorimotor data share common mathematical descriptions, one can quantify our informational sensorimotor needs using the signal processing metrics of entropy, noise, dimensionality, continuity, latency, and bandwidth. Such metrics describe in neutral terms the informational diet human brains require to self-calibrate, allowing individuals to maintain trusting relationships. With these metrics, we define the trust humans experience using the mathematical language of computational models, that is, as a primitive statistical algorithm processing finely grained sensorimotor data from neuromechanical interaction. This definition of neuromechanical trust implies that artificial sensorimotor inputs and interactions that attract low-level attention through frequent discontinuities and enhanced coherence will decalibrate a brain's representation of its world over the long term by violating the implicit statistical contract for which self-calibration evolved. Our hypersimplified mathematical understanding of human sensorimotor processing as multiscale, continuous-time vibratory interaction allows equally broad-brush descriptions of failure modes and solutions. For example, we model addiction in general as the result of homeostatic regulation gone awry in novel environments (sign reversal) and digital dependency as a sub-case in which the decalibration caused by digital sensorimotor data spurs yet more consumption of them. We predict that institutions can use these sensorimotor metrics to quantify media richness to improve employee well-being; that dyads and family-size groups will bond and heal best through low-latency, high-resolution multisensory interaction such as shared meals and reciprocated touch; and

  18. Metric reconstruction from Weyl scalars

    Energy Technology Data Exchange (ETDEWEB)

    Whiting, Bernard F; Price, Larry R [Department of Physics, PO Box 118440, University of Florida, Gainesville, FL 32611 (United States)

    2005-08-07

    The Kerr geometry has remained an elusive world in which to explore physics and delve into the more esoteric implications of general relativity. Following the discovery, by Kerr in 1963, of the metric for a rotating black hole, the most major advance has been an understanding of its Weyl curvature perturbations based on Teukolsky's discovery of separable wave equations some ten years later. In the current research climate, where experiments across the globe are preparing for the first detection of gravitational waves, a more complete understanding than concerns just the Weyl curvature is now called for. To understand precisely how comparatively small masses move in response to the gravitational waves they emit, a formalism has been developed based on a description of the whole spacetime metric perturbation in the neighbourhood of the emission region. Presently, such a description is not available for the Kerr geometry. While there does exist a prescription for obtaining metric perturbations once curvature perturbations are known, it has become apparent that there are gaps in that formalism which are still waiting to be filled. The most serious gaps include gauge inflexibility, the inability to include sources-which are essential when the emitting masses are considered-and the failure to describe the l = 0 and 1 perturbation properties. Among these latter properties of the perturbed spacetime, arising from a point mass in orbit, are the perturbed mass and axial component of angular momentum, as well as the very elusive Carter constant for non-axial angular momentum. A status report is given on recent work which begins to repair these deficiencies in our current incomplete description of Kerr metric perturbations.

  19. Metric reconstruction from Weyl scalars

    International Nuclear Information System (INIS)

    Whiting, Bernard F; Price, Larry R

    2005-01-01

    The Kerr geometry has remained an elusive world in which to explore physics and delve into the more esoteric implications of general relativity. Following the discovery, by Kerr in 1963, of the metric for a rotating black hole, the most major advance has been an understanding of its Weyl curvature perturbations based on Teukolsky's discovery of separable wave equations some ten years later. In the current research climate, where experiments across the globe are preparing for the first detection of gravitational waves, a more complete understanding than concerns just the Weyl curvature is now called for. To understand precisely how comparatively small masses move in response to the gravitational waves they emit, a formalism has been developed based on a description of the whole spacetime metric perturbation in the neighbourhood of the emission region. Presently, such a description is not available for the Kerr geometry. While there does exist a prescription for obtaining metric perturbations once curvature perturbations are known, it has become apparent that there are gaps in that formalism which are still waiting to be filled. The most serious gaps include gauge inflexibility, the inability to include sources-which are essential when the emitting masses are considered-and the failure to describe the l = 0 and 1 perturbation properties. Among these latter properties of the perturbed spacetime, arising from a point mass in orbit, are the perturbed mass and axial component of angular momentum, as well as the very elusive Carter constant for non-axial angular momentum. A status report is given on recent work which begins to repair these deficiencies in our current incomplete description of Kerr metric perturbations

  20. Sustainability Metrics: The San Luis Basin Project

    Science.gov (United States)

    Sustainability is about promoting humanly desirable dynamic regimes of the environment. Metrics: ecological footprint, net regional product, exergy, emergy, and Fisher Information. Adaptive management: (1) metrics assess problem, (2) specific problem identified, and (3) managemen...

  1. Halogen effect for improving high temperature oxidation resistance of Ti-50Al by anodization

    Science.gov (United States)

    Mo, Min-Hua; Wu, Lian-Kui; Cao, Hua-Zhen; Lin, Jun-Pin; Zheng, Guo-Qu

    2017-06-01

    The high temperature oxidation resistance of Ti-50Al was significantly improved via halogen effect which was achieved by anodizing in an ethylene glycol solution containing with fluorine ion. The anodized Ti-50Al with holes and micro-cracks could be self-repaired during oxidation at 1000 °C. The thickness of the oxide scale increases with the prolonging of oxidation time. On the basis of halogen effect for improving the high temperature oxidation resistance of Ti-50Al by anodization, only fluorine addition into the electrolyte can effectively improve the high temperature oxidation resistance of Ti-50Al.

  2. Effects of electron acceptors on removal of antibiotic resistant Escherichia coli, resistance genes and class 1 integrons under anaerobic conditions.

    Science.gov (United States)

    Yuan, Heyang; Miller, Jennifer H; Abu-Reesh, Ibrahim M; Pruden, Amy; He, Zhen

    2016-11-01

    Anaerobic biotechnologies can effectively remove antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), but there is a need to better understand the mechanisms. Here we employ bioelectrochemical systems (BES) as a platform to investigate the fate of a native tetracycline and sulfonamide-resistant Escherichia coli strain and its ARGs. The E. coli strain carrying intI1, sulI and tet(E) was isolated from domestic wastewater and dosed into a tubular BES. The BES was first operated as a microbial fuel cell (MFC), with aeration in the cathode, which resulted in enhanced removal of E. coli and ARGs by ~2 log (i.e., order of magnitude) when switched from high current to open circuit operation mode. The BES was then operated as a microbial electrolysis cell (MEC) to exclude the effects of oxygen diffusion, and the removal of E. coli and ARGs during the open circuit configuration was again 1-2 log higher than that at high current mode. Significant correlations of E. coli vs. current (R(2)=0.73) and ARGs vs. E. coli (R(2) ranged from 0.54 to 0.87), and the fact that the BES substrate contained no electron acceptors, implied that the persistence of the E. coli and its ARGs was determined by the availability of indigenous electron acceptors in the BES, i.e., the anode electrode or the electron shuttles generated by the exoelectrogens. Subsequent experiments with pure-culture tetracycline and sulfonamide-resistant E. coli being incubated in a two-chamber MEC and serum bottles demonstrated that the E. coli could survive by respiring anode electrode and/or electron shuttles released by exoelectrogens, and ARGs persisted with their host E. coli. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study

    Science.gov (United States)

    Kephart, Wesley C.; Pledge, Coree D.; Roberson, Paul A.; Mumford, Petey W.; Romero, Matthew A.; Mobley, Christopher B.; Young, Kaelin C.; Lowery, Ryan P.; Wilson, Jacob M.; Huggins, Kevin W.; Roberts, Michael D.

    2018-01-01

    Adopting low carbohydrate, ketogenic diets remains a controversial issue for individuals who resistance train given that this form of dieting has been speculated to reduce skeletal muscle glycogen levels and stifle muscle anabolism. We sought to characterize the effects of a 12-week ketogenic diet (KD) on body composition, metabolic, and performance parameters in participants who trained recreationally at a local CrossFit facility. Twelve participants (nine males and three females, 31 ± 2 years of age, 80.3 ± 5.1 kg body mass, 22.9 ± 2.3% body fat, 1.37 back squat: body mass ratio) were divided into a control group (CTL; n = 5) and a KD group (n = 7). KD participants were given dietary guidelines to follow over 12 weeks while CTL participants were instructed to continue their normal diet throughout the study, and all participants continued their CrossFit training routine for 12 weeks. Pre, 2.5-week, and 12-week anaerobic performance tests were conducted, and pre- and 12-week tests were performed for body composition using dual X-ray absorptiometry (DXA) and ultrasound, resting energy expenditure (REE), blood-serum health markers, and aerobic capacity. Additionally, blood beta hydroxybutyrate (BHB) levels were measured weekly. Blood BHB levels were 2.8- to 9.5-fold higher in KD versus CTL throughout confirming a state of nutritional ketosis. DXA fat mass decreased by 12.4% in KD (p = 0.053). DXA total lean body mass changes were not different between groups, although DXA dual-leg lean mass decreased in the KD group by 1.4% (p = 0.068), and vastus lateralis thickness values decreased in the KD group by ~8% (p = 0.065). Changes in fasting glucose, HDL cholesterol, and triglycerides were similar between groups, although LDL cholesterol increased ~35% in KD (p = 0.048). Between-group changes in REE, one-repetition maximum (1-RM) back squat, 400 m run times, and VO2peak were similar between groups. While our n-sizes were limited, these preliminary data suggest that

  4. The Three-Month Effects of a Ketogenic Diet on Body Composition, Blood Parameters, and Performance Metrics in CrossFit Trainees: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Wesley C. Kephart

    2018-01-01

    Full Text Available Adopting low carbohydrate, ketogenic diets remains a controversial issue for individuals who resistance train given that this form of dieting has been speculated to reduce skeletal muscle glycogen levels and stifle muscle anabolism. We sought to characterize the effects of a 12-week ketogenic diet (KD on body composition, metabolic, and performance parameters in participants who trained recreationally at a local CrossFit facility. Twelve participants (nine males and three females, 31 ± 2 years of age, 80.3 ± 5.1 kg body mass, 22.9 ± 2.3% body fat, 1.37 back squat: body mass ratio were divided into a control group (CTL; n = 5 and a KD group (n = 7. KD participants were given dietary guidelines to follow over 12 weeks while CTL participants were instructed to continue their normal diet throughout the study, and all participants continued their CrossFit training routine for 12 weeks. Pre, 2.5-week, and 12-week anaerobic performance tests were conducted, and pre- and 12-week tests were performed for body composition using dual X-ray absorptiometry (DXA and ultrasound, resting energy expenditure (REE, blood-serum health markers, and aerobic capacity. Additionally, blood beta hydroxybutyrate (BHB levels were measured weekly. Blood BHB levels were 2.8- to 9.5-fold higher in KD versus CTL throughout confirming a state of nutritional ketosis. DXA fat mass decreased by 12.4% in KD (p = 0.053. DXA total lean body mass changes were not different between groups, although DXA dual-leg lean mass decreased in the KD group by 1.4% (p = 0.068, and vastus lateralis thickness values decreased in the KD group by ~8% (p = 0.065. Changes in fasting glucose, HDL cholesterol, and triglycerides were similar between groups, although LDL cholesterol increased ~35% in KD (p = 0.048. Between-group changes in REE, one-repetition maximum (1-RM back squat, 400 m run times, and VO2peak were similar between groups. While our n-sizes were limited, these preliminary data suggest

  5. Effect of specific resistance training on forearm pain and work disability in industrial technicians: cluster randomised controlled trial

    DEFF Research Database (Denmark)

    Andersen, Lars Louis; Jakobsen, Markus D; Pedersen, Mogens Theisen

    2012-01-01

    To determine the effect of specific resistance training on forearm pain and work disability in industrial technicians.......To determine the effect of specific resistance training on forearm pain and work disability in industrial technicians....

  6. Indefinite metric and regularization of electrodynamics

    International Nuclear Information System (INIS)

    Gaudin, M.

    1984-06-01

    The invariant regularization of Pauli and Villars in quantum electrodynamics can be considered as deriving from a local and causal lagrangian theory for spin 1/2 bosons, by introducing an indefinite metric and a condition on the allowed states similar to the Lorentz condition. The consequences are the asymptotic freedom of the photon's propagator. We present a calcultion of the effective charge to the fourth order in the coupling as a function of the auxiliary masses, the theory avoiding all mass divergencies to this order [fr

  7. Crowdsourcing metrics of digital collections

    Directory of Open Access Journals (Sweden)

    Tuula Pääkkönen

    2015-12-01

    Full Text Available In the National Library of Finland (NLF there are millions of digitized newspaper and journal pages, which are openly available via the public website  http://digi.kansalliskirjasto.fi. To serve users better, last year the front end was completely overhauled with its main aim in crowdsourcing features, e.g., by giving end-users the opportunity to create digital clippings and a personal scrapbook from the digital collections. But how can you know whether crowdsourcing has had an impact? How much crowdsourcing functionalities have been used so far? Did crowdsourcing work? In this paper the statistics and metrics of a recent crowdsourcing effort are analysed across the different digitized material types (newspapers, journals, ephemera. The subjects, categories and keywords given by the users are analysed to see which topics are the most appealing. Some notable public uses of the crowdsourced article clippings are highlighted. These metrics give us indications on how the end-users, based on their own interests, are investigating and using the digital collections. Therefore, the suggested metrics illustrate the versatility of the information needs of the users, varying from citizen science to research purposes. By analysing the user patterns, we can respond to the new needs of the users by making minor changes to accommodate the most active participants, while still making the service more approachable for those who are trying out the functionalities for the first time. Participation in the clippings and annotations can enrich the materials in unexpected ways and can possibly pave the way for opportunities of using crowdsourcing more also in research contexts. This creates more opportunities for the goals of open science since source data becomes ­available, making it possible for researchers to reach out to the general public for help. In the long term, utilizing, for example, text mining methods can allow these different end-user segments to

  8. A family of metric gravities

    Science.gov (United States)

    Shuler, Robert

    2018-04-01

    The goal of this paper is to take a completely fresh approach to metric gravity, in which the metric principle is strictly adhered to but its properties in local space-time are derived from conservation principles, not inferred from a global field equation. The global field strength variation then gains some flexibility, but only in the regime of very strong fields (2nd-order terms) whose measurement is now being contemplated. So doing provides a family of similar gravities, differing only in strong fields, which could be developed into meaningful verification targets for strong fields after the manner in which far-field variations were used in the 20th century. General Relativity (GR) is shown to be a member of the family and this is demonstrated by deriving the Schwarzschild metric exactly from a suitable field strength assumption. The method of doing so is interesting in itself because it involves only one differential equation rather than the usual four. Exact static symmetric field solutions are also given for one pedagogical alternative based on potential, and one theoretical alternative based on inertia, and the prospects of experimentally differentiating these are analyzed. Whether the method overturns the conventional wisdom that GR is the only metric theory of gravity and that alternatives must introduce additional interactions and fields is somewhat semantical, depending on whether one views the field strength assumption as a field and whether the assumption that produces GR is considered unique in some way. It is of course possible to have other fields, and the local space-time principle can be applied to field gravities which usually are weak-field approximations having only time dilation, giving them the spatial factor and promoting them to full metric theories. Though usually pedagogical, some of them are interesting from a quantum gravity perspective. Cases are noted where mass measurement errors, or distributions of dark matter, can cause one

  9. Effects of silicon on plant resistance to environmental stresses: review

    Science.gov (United States)

    Balakhnina, T.; Borkowska, A.

    2013-03-01

    The role of exogenous silicon in enhancing plant resistance to various abiotic stressors: salinity, drought, metal toxicities and ultraviolet radiation are presented. The data on possible involvement of silicon in reducing the reactive oxygen species generation, intensity of lipid peroxidation, and in some cases, increasing the activity of enzymes of the reactive oxygen species detoxificators: superoxide dismutase, ascorbate peroxidase, glutathione reductase, guaiacol peroxidase and catalase are analyzed.

  10. EFFECT OF TOBRACEF IN CARBAPENEM RESISTANT PNEUMONIA INFECTION

    OpenAIRE

    A. Ahmad, V.K. Dwivedi * , and M. Chaudhary

    2010-01-01

    To determine ef ect of Tobracef and imipenem drug on antioxidant enzyme actvity and lipid peroxidation leveland some biochemical parametrs in carbapenem resistant pneumonia infection rat model. Total 40 rats wereselected and diveded into 4 groups of 10 rats each. Group I was control group; group II was infected via A.baumanni bacterial strain. Group III and IV were infected plus treated group with tobracef and imipenemdrugs.Our results showed that a significant (p

  11. Metrics for Evaluation of Student Models

    Science.gov (United States)

    Pelanek, Radek

    2015-01-01

    Researchers use many different metrics for evaluation of performance of student models. The aim of this paper is to provide an overview of commonly used metrics, to discuss properties, advantages, and disadvantages of different metrics, to summarize current practice in educational data mining, and to provide guidance for evaluation of student…

  12. Context-dependent ATC complexity metric

    NARCIS (Netherlands)

    Mercado Velasco, G.A.; Borst, C.

    2015-01-01

    Several studies have investigated Air Traffic Control (ATC) complexity metrics in a search for a metric that could best capture workload. These studies have shown how daunting the search for a universal workload metric (one that could be applied in different contexts: sectors, traffic patterns,

  13. Properties of C-metric spaces

    Science.gov (United States)

    Croitoru, Anca; Apreutesei, Gabriela; Mastorakis, Nikos E.

    2017-09-01

    The subject of this paper belongs to the theory of approximate metrics [23]. An approximate metric on X is a real application defined on X × X that satisfies only a part of the metric axioms. In a recent paper [23], we introduced a new type of approximate metric, named C-metric, that is an application which satisfies only two metric axioms: symmetry and triangular inequality. The remarkable fact in a C-metric space is that a topological structure induced by the C-metric can be defined. The innovative idea of this paper is that we obtain some convergence properties of a C-metric space in the absence of a metric. In this paper we investigate C-metric spaces. The paper is divided into four sections. Section 1 is for Introduction. In Section 2 we recall some concepts and preliminary results. In Section 3 we present some properties of C-metric spaces, such as convergence properties, a canonical decomposition and a C-fixed point theorem. Finally, in Section 4 some conclusions are highlighted.

  14. Synergistic effects of antimicrobial peptide DP7 combined with antibiotics against multidrug-resistant bacteria

    Directory of Open Access Journals (Sweden)

    Wu X

    2017-03-01

    Full Text Available Xiaozhe Wu,1 Zhan Li,1 Xiaolu Li,2,3 Yaomei Tian,1 Yingzi Fan,1 Chaoheng Yu,1 Bailing Zhou,1 Yi Liu,4 Rong Xiang,5 Li Yang1 1State Key Laboratory of Biotherapy/Collaborative Innovation Center of Biotherapy, West China Hospital, Sichuan University, 2International Center for Translational Chinese Medicine, Sichuan Academy of Chinese Medicine Sciences, Chengdu, 3Department of Plastic and Burn Surgery, Affiliated Hospital of Southwest Medical University, Luzhou, 4Department of Microbial Examination, Sichuan Center for Disease Control and Prevention, Chengdu, 5Nankai University School of Medicine, Tianjin, People’s Republic of China Abstract: Antibiotic-resistant bacteria present a great threat to public health. In this study, the synergistic effects of antimicrobial peptides (AMPs and antibiotics on several multidrug-resistant bacterial strains were studied, and their synergistic effects on azithromycin (AZT-resistance genes were analyzed to determine the relationships between antimicrobial resistance and these synergistic effects. A checkerboard method was used to evaluate the synergistic effects of AMPs (DP7 and CLS001 and several antibiotics (gentamicin, vancomycin [VAN], AZT, and amoxicillin on clinical bacterial strains (Staphylococcus aureus, Pseudomonas aeruginosa, Acinetobacter baumannii, and Escherichia coli. The AZT-resistance genes (ermA, ermB, ermC, mefA, and msrA were identified in the resistant strains using quantitative polymerase chain reaction. For all the clinical isolates tested that were resistant to different antibiotics, DP7 had high antimicrobial activity (≤32 mg/L. When DP7 was combined with VAN or AZT, the effect was most frequently synergistic. When we studied the resistance genes of the AZT-resistant isolates, the synergistic effect of DP7–AZT occurred most frequently in highly resistant strains or strains carrying more than two AZT-resistance genes. A transmission electron microscopic analysis of the S. aureus

  15. Landscape metrics for three-dimension urban pattern recognition

    Science.gov (United States)

    Liu, M.; Hu, Y.; Zhang, W.; Li, C.

    2017-12-01

    Understanding how landscape pattern determines population or ecosystem dynamics is crucial for managing our landscapes. Urban areas are becoming increasingly dominant social-ecological systems, so it is important to understand patterns of urbanization. Most studies of urban landscape pattern examine land-use maps in two dimensions because the acquisition of 3-dimensional information is difficult. We used Brista software based on Quickbird images and aerial photos to interpret the height of buildings, thus incorporating a 3-dimensional approach. We estimated the feasibility and accuracy of this approach. A total of 164,345 buildings in the Liaoning central urban agglomeration of China, which included seven cities, were measured. Twelve landscape metrics were proposed or chosen to describe the urban landscape patterns in 2- and 3-dimensional scales. The ecological and social meaning of landscape metrics were analyzed with multiple correlation analysis. The results showed that classification accuracy compared with field surveys was 87.6%, which means this method for interpreting building height was acceptable. The metrics effectively reflected the urban architecture in relation to number of buildings, area, height, 3-D shape and diversity aspects. We were able to describe the urban characteristics of each city with these metrics. The metrics also captured ecological and social meanings. The proposed landscape metrics provided a new method for urban landscape analysis in three dimensions.

  16. Measures of agreement between computation and experiment:validation metrics.

    Energy Technology Data Exchange (ETDEWEB)

    Barone, Matthew Franklin; Oberkampf, William Louis

    2005-08-01

    With the increasing role of computational modeling in engineering design, performance estimation, and safety assessment, improved methods are needed for comparing computational results and experimental measurements. Traditional methods of graphically comparing computational and experimental results, though valuable, are essentially qualitative. Computable measures are needed that can quantitatively compare computational and experimental results over a range of input, or control, variables and sharpen assessment of computational accuracy. This type of measure has been recently referred to as a validation metric. We discuss various features that we believe should be incorporated in a validation metric and also features that should be excluded. We develop a new validation metric that is based on the statistical concept of confidence intervals. Using this fundamental concept, we construct two specific metrics: one that requires interpolation of experimental data and one that requires regression (curve fitting) of experimental data. We apply the metrics to three example problems: thermal decomposition of a polyurethane foam, a turbulent buoyant plume of helium, and compressibility effects on the growth rate of a turbulent free-shear layer. We discuss how the present metrics are easily interpretable for assessing computational model accuracy, as well as the impact of experimental measurement uncertainty on the accuracy assessment.

  17. Advanced spatial metrics analysis in cellular automata land use and cover change modeling

    International Nuclear Information System (INIS)

    Zamyatin, Alexander; Cabral, Pedro

    2011-01-01

    This paper proposes an approach for a more effective definition of cellular automata transition rules for landscape change modeling using an advanced spatial metrics analysis. This approach considers a four-stage methodology based on: (i) the search for the appropriate spatial metrics with minimal correlations; (ii) the selection of the appropriate neighborhood size; (iii) the selection of the appropriate technique for spatial metrics application; and (iv) the analysis of the contribution level of each spatial metric for joint use. The case study uses an initial set of 7 spatial metrics of which 4 are selected for modeling. Results show a better model performance when compared to modeling without any spatial metrics or with the initial set of 7 metrics.

  18. Study of the effectiveness of the US safety standard for child resistant cigarette lighters

    OpenAIRE

    Smith, L; Greene, M; Singh, H

    2002-01-01

    Objective: The purpose of this research is to evaluate the effectiveness of the US Consumer Product Safety Commission's (CPSC) Safety Standard for Cigarette Lighters, which requires that disposable cigarette lighters be resistant to operation by children younger than age 5.

  19. Residual stress effects on the impact resistance and strength of fiber composites

    Science.gov (United States)

    Chamis, C. C.

    1973-01-01

    Equations have been derived to predict degradation effects of microresidual stresses on impact resistance of unidirectional fiber composites. Equations also predict lamination residual stresses in multilayered angle ply composites.

  20. Effects of electrode material and configuration on the characteristics of planar resistive switching devices

    KAUST Repository

    Peng, H.Y.; Pu, L.; Wu, J.C.; Cha, Dong Kyu; Hong, J.H.; Lin, W.N.; Li, Yangyang; Ding, Junfeng; David, A.; Li, K.; Wu, Tao

    2013-01-01

    We report that electrode engineering, particularly tailoring the metal work function, measurement configuration and geometric shape, has significant effects on the bipolar resistive switching (RS) in lateral memory devices based on self-doped SrTiO3

  1. Effects of electron acceptors on removal of antibiotic resistant Escherichia coli, resistance genes and class 1 integrons under anaerobic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Heyang; Miller, Jennifer H. [Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 (United States); Abu-Reesh, Ibrahim M. [Department of Chemical Engineering, Qatar University, P.O. Box 2713, Doha (Qatar); Pruden, Amy [Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 (United States); He, Zhen, E-mail: zhenhe@vt.edu [Department of Civil and Environmental Engineering, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061 (United States)

    2016-11-01

    Anaerobic biotechnologies can effectively remove antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), but there is a need to better understand the mechanisms. Here we employ bioelectrochemical systems (BES) as a platform to investigate the fate of a native tetracycline and sulfonamide-resistant Escherichia coli strain and its ARGs. The E. coli strain carrying intI1, sulI and tet(E) was isolated from domestic wastewater and dosed into a tubular BES. The BES was first operated as a microbial fuel cell (MFC), with aeration in the cathode, which resulted in enhanced removal of E. coli and ARGs by ~ 2 log (i.e., order of magnitude) when switched from high current to open circuit operation mode. The BES was then operated as a microbial electrolysis cell (MEC) to exclude the effects of oxygen diffusion, and the removal of E. coli and ARGs during the open circuit configuration was again 1–2 log higher than that at high current mode. Significant correlations of E. coli vs. current (R{sup 2} = 0.73) and ARGs vs. E. coli (R{sup 2} ranged from 0.54 to 0.87), and the fact that the BES substrate contained no electron acceptors, implied that the persistence of the E. coli and its ARGs was determined by the availability of indigenous electron acceptors in the BES, i.e., the anode electrode or the electron shuttles generated by the exoelectrogens. Subsequent experiments with pure-culture tetracycline and sulfonamide-resistant E. coli being incubated in a two-chamber MEC and serum bottles demonstrated that the E. coli could survive by respiring anode electrode and/or electron shuttles released by exoelectrogens, and ARGs persisted with their host E. coli. - Highlights: • The fate of an antibiotic resistant E. coli stain and its ARGs in BES is studied. • The removal of the E. coli and its ARGs is enhanced with decreased current. • The ARGs are removed when the host E. coli dies and persist when the host survives. • The survival of the E. coli depends

  2. Effects of electron acceptors on removal of antibiotic resistant Escherichia coli, resistance genes and class 1 integrons under anaerobic conditions

    International Nuclear Information System (INIS)

    Yuan, Heyang; Miller, Jennifer H.; Abu-Reesh, Ibrahim M.; Pruden, Amy; He, Zhen

    2016-01-01

    Anaerobic biotechnologies can effectively remove antibiotic resistant bacteria (ARB) and antibiotic resistance genes (ARGs), but there is a need to better understand the mechanisms. Here we employ bioelectrochemical systems (BES) as a platform to investigate the fate of a native tetracycline and sulfonamide-resistant Escherichia coli strain and its ARGs. The E. coli strain carrying intI1, sulI and tet(E) was isolated from domestic wastewater and dosed into a tubular BES. The BES was first operated as a microbial fuel cell (MFC), with aeration in the cathode, which resulted in enhanced removal of E. coli and ARGs by ~ 2 log (i.e., order of magnitude) when switched from high current to open circuit operation mode. The BES was then operated as a microbial electrolysis cell (MEC) to exclude the effects of oxygen diffusion, and the removal of E. coli and ARGs during the open circuit configuration was again 1–2 log higher than that at high current mode. Significant correlations of E. coli vs. current (R"2 = 0.73) and ARGs vs. E. coli (R"2 ranged from 0.54 to 0.87), and the fact that the BES substrate contained no electron acceptors, implied that the persistence of the E. coli and its ARGs was determined by the availability of indigenous electron acceptors in the BES, i.e., the anode electrode or the electron shuttles generated by the exoelectrogens. Subsequent experiments with pure-culture tetracycline and sulfonamide-resistant E. coli being incubated in a two-chamber MEC and serum bottles demonstrated that the E. coli could survive by respiring anode electrode and/or electron shuttles released by exoelectrogens, and ARGs persisted with their host E. coli. - Highlights: • The fate of an antibiotic resistant E. coli stain and its ARGs in BES is studied. • The removal of the E. coli and its ARGs is enhanced with decreased current. • The ARGs are removed when the host E. coli dies and persist when the host survives. • The survival of the E. coli depends on the

  3. Effects of Resistance Exercise Intensity on Cytokine and Chemokine Gene Expression in Atopic Dermatitis Mouse Model

    Directory of Open Access Journals (Sweden)

    Eun-Ju Choi

    2018-04-01

    Full Text Available Background and Objective: Although the evidence is unclear, literature indicates that resistance exercise reduces inflammation in colorectal disease. The purpose of this study was to identify the effects of colon tissue on cytokine and chemokine gene expression with changes in resistance exercise intensity. Material and Methods: We divided male BABL/c mice into 6 groups (each group n=10, total=60 (control group: CON, low resistance exercise group: EX_L, high resistance exercise group: EX_H, atopic dermatitis group: AD, atopic dermatitis+low resistance exercise group: AD+EX_L, atopic dermatitis+high resistance exercise group: AD+EX_H and subjected them to ladder climbing resistance exercise for 4 weeks. After 24 h of each exercise schedule, a real-time polymerase chain reaction was performed to determine mRNA expression of interleukin-6 (IL-6 and chemokine ligand 20 (CCL20. Results: The AD group showed significantly higher mRNA expression of IL-6 and CCL20 compared with the CON, EX_L, EX_H, AD+EX_L, and AD+EX_H groups (p<0.05. Conclusion: In conclusion, both high and low resistance exercise effectively decreases the concentration of IL-6 and CCL20 in mice with and without AD.

  4. The Effect of a Pulsed Magnetic Field on Domain Wall Resistance in Magnetic Nanowires

    Energy Technology Data Exchange (ETDEWEB)

    Majidi, R; Tehranchi, M M; Tabrizi, K Ghafoori [Department of Physics, G.C., Shahid Beheshti University, Evin, 19838-63113, Tehran (Iran, Islamic Republic of); Phirouznia, A, E-mail: Teranchi@cc.sbu.ac.ir [Department of Physics, Azarbaijan University of Tarbiat Moallem, 53714-161 Tabriz (Iran, Islamic Republic of)

    2011-04-01

    The effect of a pulsed magnetic field on domain wall magnetoresistance for an ideal one-dimensional magnetic nanowire with a domain wall has been investigated. The analysis has been based on the Boltzmann transport equation, within the relaxation time approximation. The results indicate that the domain wall resistance increase when enhancing the magnetic field. The evaluation of local magnetization has been considered in the presence of a pulsed magnetic field. The time evaluation of the magnetization also has an effect on the domain wall resistance. The resistance depends on the contribution of the Zeeman and exchange interactions.

  5. The Effect of a Pulsed Magnetic Field on Domain Wall Resistance in Magnetic Nanowires

    International Nuclear Information System (INIS)

    Majidi, R; Tehranchi, M M; Tabrizi, K Ghafoori; Phirouznia, A

    2011-01-01

    The effect of a pulsed magnetic field on domain wall magnetoresistance for an ideal one-dimensional magnetic nanowire with a domain wall has been investigated. The analysis has been based on the Boltzmann transport equation, within the relaxation time approximation. The results indicate that the domain wall resistance increase when enhancing the magnetic field. The evaluation of local magnetization has been considered in the presence of a pulsed magnetic field. The time evaluation of the magnetization also has an effect on the domain wall resistance. The resistance depends on the contribution of the Zeeman and exchange interactions.

  6. Effect of yttrium chromite doping on its resistance to high-temperature salt and gas corrosions

    International Nuclear Information System (INIS)

    Oryshich, I.V.; Poryadchenko, N.E.; Rakitskij, A.N.; Bega, N.D.

    1996-01-01

    Effect of yttrium chromite doping with 2-4 group metal oxides on the corrosion resistance in the air at 1300 C during 5 hours and in sodium chloride and sulfate melts at 900 C during 20 hours is investigated. A notable increase of corrosion resistance is achieved under complex doping with zirconium and magnesium oxides in a quantity, close to solubility in yttrium oxide and solubility by aluminium oxide. Doping with calcium and strontium oxides in the quantities, dose to solubility in yttrium oxide does not produce any notable effect, and at higher concentrations it reduces the corrosion resistance in media indicated. Refs. 8, refs. 2, tabs. 1

  7. Metric preheating and limitations of linearized gravity

    International Nuclear Information System (INIS)

    Bassett, Bruce A.; Tamburini, Fabrizio; Kaiser, David I.; Maartens, Roy

    1999-01-01

    During the preheating era after inflation, resonant amplification of quantum field fluctuations takes place. Recently it has become clear that this must be accompanied by resonant amplification of scalar metric fluctuations, since the two are united by Einstein's equations. Furthermore, this 'metric preheating' enhances particle production, and leads to gravitational rescattering effects even at linear order. In multi-field models with strong preheating (q>>1), metric perturbations are driven non-linear, with the strongest amplification typically on super-Hubble scales (k→0). This amplification is causal, being due to the super-Hubble coherence of the inflaton condensate, and is accompanied by resonant growth of entropy perturbations. The amplification invalidates the use of the linearized Einstein field equations, irrespective of the amount of fine-tuning of the initial conditions. This has serious implications on all scales - from large-angle cosmic microwave background (CMB) anisotropies to primordial black holes. We investigate the (q,k) parameter space in a two-field model, and introduce the time to non-linearity, t nl , as the timescale for the breakdown of the linearized Einstein equations. t nl is a robust indicator of resonance behavior, showing the fine structure in q and k that one expects from a quasi-Floquet system, and we argue that t nl is a suitable generalization of the static Floquet index in an expanding universe. Backreaction effects are expected to shut down the linear resonances, but cannot remove the existing amplification, which threatens the viability of strong preheating when confronted with the CMB. Mode-mode coupling and turbulence tend to re-establish scale invariance, but this process is limited by causality and for small k the primordial scale invariance of the spectrum may be destroyed. We discuss ways to escape the above conclusions, including secondary phases of inflation and preheating solely to fermions. The exclusion principle

  8. On characterizations of quasi-metric completeness

    Energy Technology Data Exchange (ETDEWEB)

    Dag, H.; Romaguera, S.; Tirado, P.

    2017-07-01

    Hu proved in [4] that a metric space (X, d) is complete if and only if for any closed subspace C of (X, d), every Banach contraction on C has fixed point. Since then several authors have investigated the problem of characterizing the metric completeness by means of fixed point theorems. Recently this problem has been studied in the more general context of quasi-metric spaces for different notions of completeness. Here we present a characterization of a kind of completeness for quasi-metric spaces by means of a quasi-metric versions of Hu’s theorem. (Author)

  9. Sheet resistance effects in mercury cadmium telluride implanted photodiodes

    International Nuclear Information System (INIS)

    Fiorito, G.; Gasparrini, G.; Svelto, F.

    1977-01-01

    The frequency response of Hg + implanted Hgsub(1-x)Cdsub(x)Te photodiodes is discussed. This analysis, evaluating both the response to fast laser pulses and the 3 dB rolloff of the diode shot-noise spectrum, showed the necessity of adopting a distributed equivalent circuit model taking into account the implanted layer sheet resistance. Frequency behaviour, in fact, proved not to match a simple p-n junction model based on a lumped standard equivalent circuit. On this basis apparent anomalies previously reported can be explained, and useful suggestions can be obtained for design and fabrication of fast detectors. (author)

  10. Alternative Evolutionary Paths to Bacterial Antibiotic Resistance Cause Distinct Collateral Effects.

    Science.gov (United States)

    Barbosa, Camilo; Trebosc, Vincent; Kemmer, Christian; Rosenstiel, Philip; Beardmore, Robert; Schulenburg, Hinrich; Jansen, Gunther

    2017-09-01

    When bacteria evolve resistance against a particular antibiotic, they may simultaneously gain increased sensitivity against a second one. Such collateral sensitivity may be exploited to develop novel, sustainable antibiotic treatment strategies aimed at containing the current, dramatic spread of drug resistance. To date, the presence and molecular basis of collateral sensitivity has only been studied in few bacterial species and is unknown for opportunistic human pathogens such as Pseudomonas aeruginosa. In the present study, we assessed patterns of collateral effects by experimentally evolving 160 independent populations of P. aeruginosa to high levels of resistance against eight commonly used antibiotics. The bacteria evolved resistance rapidly and expressed both collateral sensitivity and cross-resistance. The pattern of such collateral effects differed to those previously reported for other bacterial species, suggesting interspecific differences in the underlying evolutionary trade-offs. Intriguingly, we also identified contrasting patterns of collateral sensitivity and cross-resistance among the replicate populations adapted to the same drug. Whole-genome sequencing of 81 independently evolved populations revealed distinct evolutionary paths of resistance to the selective drug, which determined whether bacteria became cross-resistant or collaterally sensitive towards others. Based on genomic and functional genetic analysis, we demonstrate that collateral sensitivity can result from resistance mutations in regulatory genes such as nalC or mexZ, which mediate aminoglycoside sensitivity in β-lactam-adapted populations, or the two-component regulatory system gene pmrB, which enhances penicillin sensitivity in gentamicin-resistant populations. Our findings highlight substantial variation in the evolved collateral effects among replicates, which in turn determine their potential in antibiotic therapy. © The Author 2017. Published by Oxford University Press on

  11. Circumferential or sectored beam arrangements for stereotactic body radiation therapy (SBRT) of primary lung tumors: Effect on target and normal-structure dose-volume metrics

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, Mara W. [Broad Institute of MIT and Harvard, Cambridge, MA (United States); Department of Physics, Brandeis University, Waltham, MA (United States); Kato, Catherine M. [Macalester College, St. Paul, MN (United States); Carson, Kelly M.P. [The University of North Carolina, Chapel Hill, NC (United States); Matsunaga, Nathan M. [Santa Clara University, Santa Clara, CA (United States); Arao, Robert F. [Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR (United States); Doss, Emily J. [Department of Internal Medicine, Providence St. Vincent Medical Center, Portland, OR (United States); McCracken, Charles L. [Department of Radiation Medicine, Oregon Health and Science University, Portland, OR (United States); Meng, Lu Z. [Department of Radiation Oncology, University of California Davis Comprehensive Cancer Center, Sacramento, CA (United States); Chen, Yiyi [Department of Public Health and Preventive Medicine, Oregon Health and Science University, Portland, OR (United States); Laub, Wolfram U.; Fuss, Martin [Department of Radiation Medicine, Oregon Health and Science University, Portland, OR (United States); Department of Nuclear Engineering and Radiation Health Physics, Oregon State University, Corvallis, OR (United States); Tanyi, James A., E-mail: tanyij@ohsu.edu [Department of Radiation Medicine, Oregon Health and Science University, Portland, OR (United States); Department of Nuclear Engineering and Radiation Health Physics, Oregon State University, Corvallis, OR (United States)

    2013-01-01

    To compare 2 beam arrangements, sectored (beam entry over ipsilateral hemithorax) vs circumferential (beam entry over both ipsilateral and contralateral lungs), for static-gantry intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) delivery techniques with respect to target and organs-at-risk (OAR) dose-volume metrics, as well as treatment delivery efficiency. Data from 60 consecutive patients treated using stereotactic body radiation therapy (SBRT) for primary non–small-cell lung cancer (NSCLC) formed the basis of this study. Four treatment plans were generated per data set: IMRT/VMAT plans using sectored (-s) and circumferential (-c) configurations. The prescribed dose (PD) was 60 Gy in 5 fractions to 95% of the planning target volume (PTV) (maximum PTV dose ∼ 150% PD) for a 6-MV photon beam. Plan conformality, R{sub 50} (ratio of volume circumscribed by the 50% isodose line and the PTV), and D{sub 2} {sub cm} (D{sub max} at a distance ≥2 cm beyond the PTV) were evaluated. For lungs, mean doses (mean lung dose [MLD]) and percent V{sub 30}/V{sub 20}/V{sub 10}/V{sub 5} Gy were assessed. Spinal cord and esophagus D{sub max} and D{sub 5}/D{sub 50} were computed. Chest wall (CW) D{sub max} and absolute V{sub 30}/V{sub 20}/V{sub 10}/V{sub 5} {sub Gy} were reported. Sectored SBRT planning resulted in significant decrease in contralateral MLD and V{sub 10}/V{sub 5} {sub Gy}, as well as contralateral CW D{sub max} and V{sub 10}/V{sub 5} {sub Gy} (all p < 0.001). Nominal reductions of D{sub max} and D{sub 5}/D{sub 50} for the spinal cord with sectored planning did not reach statistical significance for static-gantry IMRT, although VMAT metrics did show a statistically significant decrease (all p < 0.001). The respective measures for esophageal doses were significantly lower with sectored planning (p < 0.001). Despite comparable dose conformality, irrespective of planning configuration, R{sub 50} significantly improved with IMRT

  12. The Metric of Colour Space

    DEFF Research Database (Denmark)

    Gravesen, Jens

    2015-01-01

    and found the MacAdam ellipses which are often interpreted as defining the metric tensor at their centres. An important question is whether it is possible to define colour coordinates such that the Euclidean distance in these coordinates correspond to human perception. Using cubic splines to represent......The space of colours is a fascinating space. It is a real vector space, but no matter what inner product you put on the space the resulting Euclidean distance does not correspond to human perception of difference between colours. In 1942 MacAdam performed the first experiments on colour matching...

  13. Product Operations Status Summary Metrics

    Science.gov (United States)

    Takagi, Atsuya; Toole, Nicholas

    2010-01-01

    The Product Operations Status Summary Metrics (POSSUM) computer program provides a readable view into the state of the Phoenix Operations Product Generation Subsystem (OPGS) data pipeline. POSSUM provides a user interface that can search the data store, collect product metadata, and display the results in an easily-readable layout. It was designed with flexibility in mind for support in future missions. Flexibility over various data store hierarchies is provided through the disk-searching facilities of Marsviewer. This is a proven program that has been in operational use since the first day of the Phoenix mission.

  14. Web metrics for library and information professionals

    CERN Document Server

    Stuart, David

    2014-01-01

    This is a practical guide to using web metrics to measure impact and demonstrate value. The web provides an opportunity to collect a host of different metrics, from those associated with social media accounts and websites to more traditional research outputs. This book is a clear guide for library and information professionals as to what web metrics are available and how to assess and use them to make informed decisions and demonstrate value. As individuals and organizations increasingly use the web in addition to traditional publishing avenues and formats, this book provides the tools to unlock web metrics and evaluate the impact of this content. The key topics covered include: bibliometrics, webometrics and web metrics; data collection tools; evaluating impact on the web; evaluating social media impact; investigating relationships between actors; exploring traditional publications in a new environment; web metrics and the web of data; the future of web metrics and the library and information professional.Th...

  15. A reanalysis of resistive size effects in tungsten

    International Nuclear Information System (INIS)

    Sambles, J.R.; Mundy, J.N.

    1983-01-01

    A reanalysis of available data on the influence of surface scattering upon the resistivity of high-purity tungsten is presented. It is shown that some of the data appear to fit quite well to Soffer's model of surface scattering. From this new analysis values for the product rhosub(infinity)lambdasub(infinity) (bulk resistivity times bulk mean free path) may be obtained lying in the range 1.0-1.7 fΩ m 2 . Early data, which could not be interpreted using Fuchs' theory of surface scattering, may now be explained and yield surface roughness ratios (ratio of root mean square height of deviations from the mean surface to the Fermi wavelength) of the order of 0.2-2.5, typical of the value expected for atomically smooth to atomically rough surfaces. However, more recent data violate Soffer's theory in a convincing fashion. They illustrate fully the severe dangers of using a theory to interpret data for which it is not at all applicable. The Fermi surface of tungsten by no means approximates a simple sphere (one of the basic assumptions of the Soffer model). Hence such a naive treatment as Fuchs' leads to meaningless parameters such as quoted above. This paper is presented as a warning to all experimentalists who attempt to interpret data from metals with complex Fermi surfaces in a simple-minded fashion (e.g. using Fuchs' model). (author)

  16. Effect of displacement on resistance and capacitance of polyaniline film

    International Nuclear Information System (INIS)

    Karimov, Khasan Sanginovich; Saeed, Muhammad Tariq; Khalid, Fazal Ahmad; Moiz, Syed Abdul

    2011-01-01

    This paper investigates the properties of displacement sensors based on polyaniline (PANI) films. About 1 wt% of PANI micropowder is mixed and stirred in a solution of 90 wt% water and 10 wt% alcohol at room temperature. The films of PANI are deposited from solution by drop-casting on Ag electrodes, which are preliminary deposited on glass substrates. The thicknesses of the PANI films are in the range of 20 μm–80 μm. A displacement sensor with polyaniline film as an active material is designed and fabricated. The investigations showed that, on average, the AC resistance of the sensor decreases by 2 times and the capacitance accordingly increases by 1.6 times as the displacement changes in the range of 0 mm–0.5 mm. The polyaniline is the only active material of the displacement sensor. The resistance and capacitance of the PANI changes under the pressure of spring and elastic rubber, and this pressure is created by the downward movement of the micrometer. (general)

  17. Fanpage metrics analysis. "Study on content engagement"

    Science.gov (United States)

    Rahman, Zoha; Suberamanian, Kumaran; Zanuddin, Hasmah Binti; Moghavvemi, Sedigheh; Nasir, Mohd Hairul Nizam Bin Md

    2016-08-01

    Social Media is now determined as an excellent communicative tool to connect directly with consumers. One of the most significant ways to connect with the consumers through these Social Networking Sites (SNS) is to create a facebook fanpage with brand contents and to place different posts periodically on these fanpages. In measuring social networking sites' effectiveness, corporate houses are now analyzing metrics in terms of calculating engagement rate, number of comments/share and likings in fanpages. So now, it is very important for the marketers to know the effectiveness of different contents or posts of fanpages in order to increase the fan responsiveness and engagement rate in the fan pages. In the study the authors have analyzed total 1834 brand posts from 17 international brands of Electronics companies. Data of 9 months (From December 2014 to August 2015) have been collected for analyses, which were available online in the Brand' fan pages. An econometrics analysis is conducted using Eviews 9, to determine the impact of different contents on fanpage engagement. The study picked the four most frequently posted content to determine their impact on PTA (people Talking About) metrics and Fanpage engagement activities.

  18. The annealing effects on irradiated SiC piezo resistive pressure sensor

    International Nuclear Information System (INIS)

    Almaz, E.; Blue, T. E.; Zhang, P.

    2009-01-01

    The effects of temperature on annealing of Silicon Carbide (SiC) piezo resistive pressure sensor which was broken after high fluence neutron irradiation, were investigated. Previously, SiC piezo resistive sensor irradiated with gamma ray and fast neutron in the Co-60 gamma-ray irradiator and Beam Port 1 (BP1) and Auxiliary Irradiation Facility (AIF) at the Ohio State University Nuclear Reactor Laboratory (OSUNRL) respectively. The Annealing temperatures were tested up to 400 C. The Pressure-Output voltage results showed recovery after annealing process on SiC piezo resistive pressure sensor. The bridge resistances of the SiC pressure sensor stayed at the same level up to 300 C. After 400 C annealing, the resistance values changed dramatically.

  19. Resistance training among young athletes: safety, efficacy and injury prevention effects.

    Science.gov (United States)

    Faigenbaum, A D; Myer, G D

    2010-01-01

    A literature review was employed to evaluate the current epidemiology of injury related to the safety and efficacy of youth resistance training. Several case study reports and retrospective questionnaires regarding resistance exercise and the competitive sports of weightlifting and powerlifting reveal that injuries have occurred in young lifters, although a majority can be classified as accidental. Lack of qualified instruction that underlies poor exercise technique and inappropriate training loads could explain, at least partly, some of the reported injuries. Current research indicates that resistance training can be a safe, effective and worthwhile activity for children and adolescents provided that qualified professionals supervise all training sessions and provide age-appropriate instruction on proper lifting procedures and safe training guidelines. Regular participation in a multifaceted resistance training programme that begins during the preseason and includes instruction on movement biomechanics may reduce the risk of sports-related injuries in young athletes. Strategies for enhancing the safety of youth resistance training are discussed.

  20. Investigation into the effect of common factors on rolling resistance of belt conveyor

    Directory of Open Access Journals (Sweden)

    Lu Yan

    2015-08-01

    Full Text Available Since indentation rolling resistance accounts for the major part of total resistance of belt conveyor, it is important to compute it using a proper method during the design and application study of the belt conveyor. First, an approximate formula for computing the indentation rolling resistance is offered. In this formula, a one-dimensional Winkler foundation and a three-parameter viscoelastic Maxwell solid model of the belt backing material are used to determine the resistance to motion of a conveyor belt over idlers. With the help of this formula, the authors analyze the effect of common factors on the rolling resistance. Finally, experiments are carried out under certain condition compared with theoretical analysis. A reasonable correlation exists between the experimental results and the theoretical formulae.

  1. Strain-Modulated Bandgap and Piezo-Resistive Effect in Black Phosphorus Field-Effect Transistors.

    Science.gov (United States)

    Zhang, Zuocheng; Li, Likai; Horng, Jason; Wang, Nai Zhou; Yang, Fangyuan; Yu, Yijun; Zhang, Yu; Chen, Guorui; Watanabe, Kenji; Taniguchi, Takashi; Chen, Xian Hui; Wang, Feng; Zhang, Yuanbo

    2017-10-11

    Energy bandgap largely determines the optical and electronic properties of a semiconductor. Variable bandgap therefore makes versatile functionality possible in a single material. In layered material black phosphorus, the bandgap can be modulated by the number of layers; as a result, few-layer black phosphorus has discrete bandgap values that are relevant for optoelectronic applications in the spectral range from red, in monolayer, to mid-infrared in the bulk limit. Here, we further demonstrate continuous bandgap modulation by mechanical strain applied through flexible substrates. The strain-modulated bandgap significantly alters the density of thermally activated carriers; we for the first time observe a large piezo-resistive effect in black phosphorus field-effect transistors (FETs) at room temperature. The effect opens up opportunities for future development of electromechanical transducers based on black phosphorus, and we demonstrate an ultrasensitive strain gauge constructed from black phosphorus thin crystals.

  2. Effects of Floor Covering Resistance of a Radiant Floor on System Energy and Exergy Performances

    DEFF Research Database (Denmark)

    Kazanci, Ongun Berk; Shukuya, Masanori; Olesen, Bjarne W.

    2016-01-01

    Floor covering resistance (material and thickness) can be influenced by subjective choices (architectural design, interior design, texture, etc.) with significant effects on the performance of a radiant heating and cooling system. To study the effects of floor covering resistance on system...... performance, a water-based radiant floor heating and cooling system (dry, wooden construction) was considered to be coupled to an air-to-water heat pump, and the effects of varying floor covering resistances (0.05 m2K/W, 0.09 m2K/W and 0.15 m2K/W) on system performance were analyzed in terms of energy...... and exergy. In order to achieve the same heating and cooling outputs, higher average water temperatures are required in the heating mode (and lower temperatures in the cooling mode) with increasing floor covering resistance. These temperature requirements decrease the heat pump’s performance (lower...

  3. Effect of ship hull form on the resistance penalty from biofouling.

    Science.gov (United States)

    Oliveira, Dinis; Larsson, Ann I; Granhag, Lena

    2018-03-01

    Hull biofouling is a well-known problem for the shipping industry, leading to increased resistance and fuel consumption. Considering that the effects of hull form on resistance are known to be higher for a less slender hull, it is hypothesised in this paper that the effect of biofouling roughness on resistance is also dependent on the hull form. To test this hypothesis, previously reported full-scale numerical results on a containership are re-analysed. Form effects on roughness penalties, corresponding to K ΔCT  = 0.058 ± 0.025, are observed at a low speed (19 knots, Re s  = 2.29 × 10 9 ), which are however cancelled out by traditionally neglected roughness effects on wave-making resistance at a higher speed (24 knots, Re s  = 2.89 × 10 9 ). It is concluded that hull form effects on biofouling penalties can be significant at low speeds, though not generalisable for higher speeds, namely when wave-making resistance corresponds to ≥ 29% of total resistance.

  4. Contrasting effects of specialist and generalist herbivores on resistance evolution in invasive plants.

    Science.gov (United States)

    Zhang, Zhijie; Pan, Xiaoyun; Blumenthal, Dana; van Kleunen, Mark; Liu, Mu; Li, Bo

    2018-04-01

    Invasive alien plants are likely to be released from specialist herbivores and at the same time encounter biotic resistance from resident generalist herbivores in their new ranges. The Shifting Defense hypothesis predicts that this will result in evolution of decreased defense against specialist herbivores and increased defense against generalist herbivores. To test this, we performed a comprehensive meta-analysis of 61 common garden studies that provide data on resistance and/or tolerance for both introduced and native populations of 32 invasive plant species. We demonstrate that introduced populations, relative to native populations, decreased their resistance against specialists, and increased their resistance against generalists. These differences were significant when resistance was measured in terms of damage caused by the herbivore, but not in terms of performance of the herbivore. Furthermore, we found the first evidence that the magnitude of resistance differences between introduced and native populations depended significantly on herbivore origin (i.e., whether the test herbivore was collected from the native or non-native range of the invasive plant). Finally, tolerance to generalists was found to be higher in introduced populations, while neither tolerance to specialists nor that to simulated herbivory differed between introduced and native plant populations. We conclude that enemy release from specialist herbivores and biotic resistance from generalist herbivores have contrasting effects on resistance evolution in invasive plants. Our results thus provide strong support for the Shifting Defense hypothesis. © 2018 by the Ecological Society of America.

  5. Metrics for building performance assurance

    Energy Technology Data Exchange (ETDEWEB)

    Koles, G.; Hitchcock, R.; Sherman, M.

    1996-07-01

    This report documents part of the work performed in phase I of a Laboratory Directors Research and Development (LDRD) funded project entitled Building Performance Assurances (BPA). The focus of the BPA effort is to transform the way buildings are built and operated in order to improve building performance by facilitating or providing tools, infrastructure, and information. The efforts described herein focus on the development of metrics with which to evaluate building performance and for which information and optimization tools need to be developed. The classes of building performance metrics reviewed are (1) Building Services (2) First Costs, (3) Operating Costs, (4) Maintenance Costs, and (5) Energy and Environmental Factors. The first category defines the direct benefits associated with buildings; the next three are different kinds of costs associated with providing those benefits; the last category includes concerns that are broader than direct costs and benefits to the building owner and building occupants. The level of detail of the various issues reflect the current state of knowledge in those scientific areas and the ability of the to determine that state of knowledge, rather than directly reflecting the importance of these issues; it intentionally does not specifically focus on energy issues. The report describes work in progress and is intended as a resource and can be used to indicate the areas needing more investigation. Other reports on BPA activities are also available.

  6. Prioritizing Urban Habitats for Connectivity Conservation: Integrating Centrality and Ecological Metrics.

    Science.gov (United States)

    Poodat, Fatemeh; Arrowsmith, Colin; Fraser, David; Gordon, Ascelin

    2015-09-01

    Connectivity among fragmented areas of habitat has long been acknowledged as important for the viability of biological conservation, especially within highly modified landscapes. Identifying important habitat patches in ecological connectivity is a priority for many conservation strategies, and the application of 'graph theory' has been shown to provide useful information on connectivity. Despite the large number of metrics for connectivity derived from graph theory, only a small number have been compared in terms of the importance they assign to nodes in a network. This paper presents a study that aims to define a new set of metrics and compares these with traditional graph-based metrics, used in the prioritization of habitat patches for ecological connectivity. The metrics measured consist of "topological" metrics, "ecological metrics," and "integrated metrics," Integrated metrics are a combination of topological and ecological metrics. Eight metrics were applied to the habitat network for the fat-tailed dunnart within Greater Melbourne, Australia. A non-directional network was developed in which nodes were linked to adjacent nodes. These links were then weighted by the effective distance between patches. By applying each of the eight metrics for the study network, nodes were ranked according to their contribution to the overall network connectivity. The structured comparison revealed the similarity and differences in the way the habitat for the fat-tailed dunnart was ranked based on different classes of metrics. Due to the differences in the way the metrics operate, a suitable metric should be chosen that best meets the objectives established by the decision maker.

  7. Human Performance Optimization Metrics: Consensus Findings, Gaps, and Recommendations for Future Research.

    Science.gov (United States)

    Nindl, Bradley C; Jaffin, Dianna P; Dretsch, Michael N; Cheuvront, Samuel N; Wesensten, Nancy J; Kent, Michael L; Grunberg, Neil E; Pierce, Joseph R; Barry, Erin S; Scott, Jonathan M; Young, Andrew J; OʼConnor, Francis G; Deuster, Patricia A

    2015-11-01

    Human performance optimization (HPO) is defined as "the process of applying knowledge, skills and emerging technologies to improve and preserve the capabilities of military members, and organizations to execute essential tasks." The lack of consensus for operationally relevant and standardized metrics that meet joint military requirements has been identified as the single most important gap for research and application of HPO. In 2013, the Consortium for Health and Military Performance hosted a meeting to develop a toolkit of standardized HPO metrics for use in military and civilian research, and potentially for field applications by commanders, units, and organizations. Performance was considered from a holistic perspective as being influenced by various behaviors and barriers. To accomplish the goal of developing a standardized toolkit, key metrics were identified and evaluated across a spectrum of domains that contribute to HPO: physical performance, nutritional status, psychological status, cognitive performance, environmental challenges, sleep, and pain. These domains were chosen based on relevant data with regard to performance enhancers and degraders. The specific objectives at this meeting were to (a) identify and evaluate current metrics for assessing human performance within selected domains; (b) prioritize metrics within each domain to establish a human performance assessment toolkit; and (c) identify scientific gaps and the needed research to more effectively assess human performance across domains. This article provides of a summary of 150 total HPO metrics across multiple domains that can be used as a starting point-the beginning of an HPO toolkit: physical fitness (29 metrics), nutrition (24 metrics), psychological status (36 metrics), cognitive performance (35 metrics), environment (12 metrics), sleep (9 metrics), and pain (5 metrics). These metrics can be particularly valuable as the military emphasizes a renewed interest in Human Dimension efforts

  8. Inter-filament resistance, effective transverse resistivity and coupling loss in superconducting multifilamentary NbTi and Nb3Sn strands

    NARCIS (Netherlands)

    Zhou, Chao; Dhalle, Marc M.J.; Nijhuis, Arend

    2012-01-01

    The effective transverse resistivity of a range of multi-filamentary Nb3Sn and NbTi strands is measured with a direct four-probe method and the data are compared to the transverse resistivity values obtained from AC coupling loss experiments. Correspondence between both is satisfactory provided that

  9. The multi-year effects of repeatedly growing cotton with moderate resistance to Meloidogyne incognita

    Science.gov (United States)

    Kemerait, Robert C.

    2009-01-01

    Meloidogyne incognita causes more damage to cotton in the US than any other pathogen. The objective of this study was to document the cumulative effect of moderate resistance on M. incognita population density, root galling, and yield suppression in the southern United States on a moderately resistant cotton genotype grown continuously for three years. Cotton genotypes were Phytogen PH98-3196 (77% suppression of M. incognita), Acala NemX (85% suppression of M. incognita), and Delta and Pine Land DP458 B/R (susceptible standard, 0% suppression). Cotton was grown in fumigated and non-fumigated plots to measure yield loss. Each genotype and nematicide combination was planted in the same place for three years at two sites to document cumulative effects. In 2006, following three years of the different genotypes, all plots at one site were planted with susceptible cotton to document residual effects of planting resistant genotypes. Root galling and nematode population densities in the soil were significantly lower, and percentage yield suppression was numerically lower, when moderately resistant cotton was grown compared to the susceptible standard in both fields in all three years. Differences between susceptible and moderately resistant genotypes are established quickly (after only one season) and then either maintained at similar levels or slightly increased in subsequent years depending on initial nematode levels. However, when susceptible cotton was grown following three years of the moderately resistant genotypes, the nematode suppression provided by moderate resistance was undetectable by the end of the first season. Moderately resistant cotton genotypes are more beneficial than previously reported and should be pursued for nematode management. Rotation of moderately resistant and susceptible cotton could be used along with nematicides to manage root-knot nematodes in a continuous cotton cropping system and reduce selection pressure on the nematodes. PMID:22661787

  10. Effect of thiazolidinedione treatment on resistin levels in insulin resistant sprague dawley rats

    International Nuclear Information System (INIS)

    Yousaf, I.; Hameed, W.; Rajput, T.A.

    2015-01-01

    Insulin resistance is manifested by decreased effect of fixed quantity of insulin on glucose metabolism leading to type 2 diabetes mellitus. Visceral obesity has been positively correlated with insulin resistance but its mechanism is not fully defined. Insulin resistance may be the consequence of adipocytokines including visfatin and resistin. This study was designed to see the effect of thiazolidinediones on levels of resistin in insulin resistant rats. Methods: Ninety Sprague Dawley rats were randomly divided into three groups. Group I served as control. Rats in Group II and III were made insulin resistant diabetics. Group III was treated with rosiglitazone after development of diabetes. Plasma glucose, serum triglycerides, HDL, TG:HDL ratio and serum resistin levels were analysed. Results: Body weight and plasma glucose were significantly increased (p<0.05) along with TG:HDL ratio (p<0.05) in group II and group III at the end of 4th week. Serum resistin levels also increased significantly (p<0.05) in group II and III at the end of 4th week. Treatment of group III with rosiglitazone led to improvement in insulin resistance with decrease in serum resistin levels (p<0.05). Conclusion: Increased serum resistin level indicates insulin resistance and impending hyperglycaemia. Thiazolidinediones augment sensitivity of insulin to restore normoglycaemia by decreasing serum resistin level. (author)

  11. [Physiological and biochemical effects of intermittent fasting combined with hunger-resistant food on mice].

    Science.gov (United States)

    Shen, Xiao-Dong; Hua, Wei-Guo; Chu, Wei-Zhong; Xu, Feng; Wang, Yu-Ying; Chen, Hui-Ju

    2006-11-01

    To observe the physiological and biochemical effects of intermittent fasting combined with hunger-resistant food on mice, and to evaluate the safety and beneficial effects of this regimen. One hundred and forty-four adult ICR mice were divided into 4 groups: standard feed AL group (ad libitum intake of standard feed), hunger-resistant food AL group (ad libitum intake of hunger-resistant food), standard feed IF group (feeding standard feed and fasting on alternate days), and hunger-resistant food IF group (feeding hunger-resistant food and fasting on alternate days). The experiment lasted for 4-8 weeks and all mice drank water freely. The quality of life, body weight, fasting blood glucose, serum lipid, blood routine test, liver and kidney functions as well as the viscera indexes were examined. Compared to the standard feed AL group, the caloric taking and the increment of body-weight were reduced (Pfasting blood glucose were reduced in standard feed IF group and hunger-resistant food IF group (Pintermittent fasting combined with hunger-resistant food is safe and beneficial to metabolic regulation, such as controlling body-weight and adjusting blood glucose and serum lipid. It is expected that development of this regimen will be helpful to the control of obesity and diabetes, etc.

  12. Bias voltage induced resistance switching effect in single-molecule magnets' tunneling junction.

    Science.gov (United States)

    Zhang, Zhengzhong; Jiang, Liang

    2014-09-12

    An electric-pulse-induced reversible resistance change effect in a molecular magnetic tunneling junction, consisting of a single-molecule magnet (SMM) sandwiched in one nonmagnetic and one ferromagnetic electrode, is theoretically investigated. By applying a time-varying bias voltage, the SMM's spin orientation can be manipulated with large bias voltage pulses. Moreover, the different magnetic configuration at high-resistance/low-resistance states can be 'read out' by utilizing relative low bias voltage. This device scheme can be implemented with current technologies (Khajetoorians et al 2013 Science 339 55) and has potential application in molecular spintronics and high-density nonvolatile memory devices.

  13. Bias voltage induced resistance switching effect in single-molecule magnets’ tunneling junction

    Science.gov (United States)

    Zhang, Zhengzhong; Jiang, Liang

    2014-09-01

    An electric-pulse-induced reversible resistance change effect in a molecular magnetic tunneling junction, consisting of a single-molecule magnet (SMM) sandwiched in one nonmagnetic and one ferromagnetic electrode, is theoretically investigated. By applying a time-varying bias voltage, the SMM's spin orientation can be manipulated with large bias voltage pulses. Moreover, the different magnetic configuration at high-resistance/low-resistance states can be ‘read out’ by utilizing relative low bias voltage. This device scheme can be implemented with current technologies (Khajetoorians et al 2013 Science 339 55) and has potential application in molecular spintronics and high-density nonvolatile memory devices.

  14. [Effects and mechanisms of plant roots on slope reinforcement and soil erosion resistance: a research review].

    Science.gov (United States)

    Xiong, Yan-Mei; Xia, Han-Ping; Li, Zhi-An; Cai, Xi-An

    2007-04-01

    Plant roots play an important role in resisting the shallow landslip and topsoil erosion of slopes by raising soil shear strength. Among the models in interpreting the mechanisms of slope reinforcement by plant roots, Wu-Waldron model is a widely accepted one. In this model, the reinforced soil strength by plant roots is positively proportional to average root tensile strength and root area ratio, the two most important factors in evaluating slope reinforcement effect of plant roots. It was found that soil erosion resistance increased with the number of plant roots, though no consistent quantitative functional relationship was observed between them. The increase of soil erosion resistance by plant roots was mainly through the actions of fiber roots less than 1 mm in diameter, while fiber roots enhanced the soil stability to resist water dispersion via increasing the number and diameter of soil water-stable aggregates. Fine roots could also improve soil permeability effectively to decrease runoff and weaken soil erosion.

  15. Effect of Resistance Training on Hematological Blood Markers in Older Men and Women: A Pilot Study

    Directory of Open Access Journals (Sweden)

    Florian Bobeuf

    2009-01-01

    Full Text Available The aim of this study was to examine the effects of resistance training on hematological blood markers in older individuals. Twenty-nine men and women participated to this study. Subjects were randomized in 2 groups: (1 control (n=13 and (2 resistance training (n=16. At baseline and after the intervention, subjects were submitted to a blood sample to determine their hematological profile (red blood cells, hemoglobin, hematocrit, platelets, leukocytes, neutrophils, lymphocytes, monocytes, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, red cell distribution width. At baseline, no difference was observed between groups. Moreover, we found no significant difference after the intervention on any of these markers. A 6-month resistance program in healthy older individuals seems to have no beneficial nor deleterious effects on hematological blood parameters. However, resistance training was well tolerated and should be recommended for other health purposes. Further studies are needed to confirm these results in a large population.

  16. Effect of Isothermal Bainitic Quenching on Rail Steel Impact Strength and Wear Resistance

    Science.gov (United States)

    Çakir, Fatih Hayati; Çelik, Osman Nuri

    2017-09-01

    The effect of heat treatment regimes on hardness, impact strength, and wear resistance of rail steel for high-speed tracks (rail quality category R350HT) is studied. Analysis of steel properties with a different structure is compared: pearlitic, and upper and lower bainite. It is shown that the steel with bainitic structure has the best impact strength, but wear resistance is better for steel with a lower bainite structure.

  17. Effect of Environmental Variables on the Flammability of Fire Resistant Materials

    OpenAIRE

    Osorio, Andres Felipe

    2014-01-01

    This work investigates the effects of external radiation, ambient pressure and microgravity on the flammability limits of fire-resistant (FR) materials. Future space missions may require spacecraft cabin environments different than those used in the International Space Station, 21%O2, 101.3kPa. Environmental variables include flow velocity, oxygen concentration, ambient pressure, micro or partial-gravity, orientation, presence of an external radiant flux, etc. Fire-resistant materials are use...

  18. Effects of N+ implantation on polysaccharide and osmosis stress resistance of liquorice

    International Nuclear Information System (INIS)

    Wei Shenglin; Wu Lijun; Yu Zengliang

    2007-01-01

    In order to study the effects of N + implantation on osmosis stress resistance of plant, the experiment was taken with liquorice as plant model and 15% PEG as the osmosis stress agent. The results showed that the stem height growth of liquorice increased by 40.2% compared with controls (p + implantation parameters may be useful to increase osmosis stress resistance cultivation of liquorice and to make it mutated with ions beam implantation. (authors)

  19. The effects of whey protein with or without carbohydrates on resistance training adaptations

    OpenAIRE

    Hulmi, Juha; Laakso, Mia; Mero, Antti; Häkkinen, Keijo; Ahtiainen, Juha; Peltonen, Heikki

    2015-01-01

    Background: Nutrition intake in the context of a resistance training (RT) bout may affect body composition and muscle strength. However, the individual and combined effects of whey protein and carbohydrates on long-term resistance training adaptations are poorly understood. Methods: A four-week preparatory RT period was conducted in previously untrained males to standardize the training background of the subjects. Thereafter, the subjects were randomized into three groups: 30 g of...

  20. Effect of Ultrasonic Waves on the Heat Resistance of Bacillus cereus and Bacillus licheniformis Spores

    Science.gov (United States)

    Burgos, J.; Ordóñez, J. A.; Sala, F.

    1972-01-01

    Heat resistance of Bacillus cereus and Bacillus licheniformis spores in quarter-strength Ringer solution decreases markedly after ultrasonic treatments which are unable to kill a significant proportion of the spore population. This effect does not seem to be caused by a loss of Ca2+ or dipicolinic acid. The use of ultrasonics to eliminate vegetative cells or to break aggregates in Bacillus spore suspensions to be used subsequently in heat resistance experiments appears to be unadvisable. PMID:4627969

  1. Effect of Omega-3 Fatty Acids Treatment on Insulin Resistance

    Directory of Open Access Journals (Sweden)

    Mogoş Tiberius

    2014-12-01

    Full Text Available Background and aims: Insulin resistance (IR is a common pathogenic factor of several diseases: diabetes mellitus, the metabolic syndrome, arterial hypertension, atherosclerosis, dyslipidemia, etc. There are many therapeutic factors involved in decreasing IR. Among them we mention metformin, pioglitazone, physical activity, weight loss, diet, etc. In the last decade, there are more observations of the influence of polyunsaturated fatty acids on IR. The most powerful seem to be omega-3 fatty acids. In our study, we wanted to asses if the administration of omega-3 fatty acids is involved in modifying IR. Materials and methods: We evaluated 126 diabetic patients with IR from January 2011 until July 2014. The study was open-label and non-randomized. For the determination of IR we used the HOMA-IR method. Results: For both males and females there was a regression of HOMA-IR during the 4 weeks of treatment with omega-3 and also after 2 weeks after stopping the administration of these fatty acids. The decrease of HOMA-IR was statistically significant (p<0.05. The statistic result observed in the next 2 weeks after stopping administration of omega-3 was also significant (p<0.05.

  2. Innocence and resisting confession during interrogation: effects on physiologic activity.

    Science.gov (United States)

    Guyll, Max; Madon, Stephanie; Yang, Yueran; Lannin, Daniel G; Scherr, Kyle; Greathouse, Sarah

    2013-10-01

    Innocent suspects may not adequately protect themselves during interrogation because they fail to fully appreciate the danger of the situation. This experiment tested whether innocent suspects experience less stress during interrogation than guilty suspects, and whether refusing to confess expends physiologic resources. After experimentally manipulating innocence and guilt, 132 participants were accused and interrogated for misconduct, and then pressured to confess. Systolic and diastolic blood pressure (SBP, DBP), heart rate (HR), respiratory sinus arrhythmia (RSA), and preejection period (PEP) responses quantified stress reactions. As hypothesized, the innocent evidenced smaller stress responses to interrogation for SBP, DBP, HR, and RSA than did the guilty. Furthermore, innocents who refused to confess exhibited greater sympathetic nervous system activation, as evidenced by shorter PEPs, than did innocent or guilty confessors. These findings suggest that innocent suspects underestimate the threat of interrogation and that resisting pressures to confess can diminish suspects' physiologic resources and lead to false confessions. PsycINFO Database Record (c) 2013 APA, all rights reserved

  3. Identification of parental line specific effects of MLF2 on resistance to coccidiosis in chickens

    Science.gov (United States)

    2011-01-01

    Background MLF2 was the candidate gene associated with coccidiosis resistance in chickens. Although single marker analysis supported the association between MLF2 and coccidiosis resistance, causative mutation relevant to coccidiosis was not identified yet. Thus, this study suggested segregation analysis of MLF2 haplotype and the association test of the other candidate genes using improved data transformation. Results A haplotype probably originated from one parental line was found out of 4 major haplotypes of MLF2. Frequency of this haplotype was 0.2 in parental chickens and its offspring in 12 families. Allele substitution effect of the MLF2 haplotype originated from a specific line was associated with increased body weight and fecal egg count explaining coccidiosis resistance. Nevertheless Box-Cox transformation was able to improve normality; association test did not produce obvious different results compared with analysis with log transformed phenotype. Conclusion Allele substitution effect analysis and classification of MLF2 haplotype identified the segregation of haplotype associated with coccidiosis resistance. The haplotype originated from a specific parental line was associated with improving disease resistance. Estimating effect of MLF2 haplotype on coccidiosis resistance will provide useful information for selecting animals or lines for future study. PMID:21645301

  4. Effects of creatine supplementation along with resistance training on urinary formaldehyde and serum enzymes in wrestlers.

    Science.gov (United States)

    Nasseri, Azadeh; Jafari, Afshar

    2016-04-01

    Formaldehyde is a cytotoxic agent produced from creatine through a metabolic pathway, and in this regard, it has been claimed that creatine supplementation could be cytotoxic. Even though the cytotoxic effects of creatine supplementation have been widely studied, yet little is known about how resistance training can alter these toxic effects. This study aimed to determine the effects of short-term creatine supplementation plus resistance training on the level of urinary formaldehyde and concentrations of serum enzymes in young male wrestlers. In a double-blind design twenty-one subjects were randomized into creatine supplementation (Cr), creatine supplementation plus resistance training (Cr + T) and placebo plus resistance training (Pl + T) groups. Participants ingested creatine (0.3 g/kg/day) or placebo for 7 days. The training protocol consisted of 3 sessions in one week, each session including three sets of 6-9 repetitions at 80-85% of one-repetition maximum for whole-body exercise. Urine and blood samples were collected at baseline and at the end of the supplementation. Creatine supplementation significantly increased the excretion rate of urinary formaldehyde in the Cr and Cr + T groups by 63.4% and 30.4%, respectively (P0.05). These findings indicate that resistance training may lower the increase of urinary formaldehyde excretion induced by creatine supplementation, suggesting that creatine consumption could be relatively less toxic when combined with resistance training.

  5. Metric approach to quantum constraints

    International Nuclear Information System (INIS)

    Brody, Dorje C; Hughston, Lane P; Gustavsson, Anna C T

    2009-01-01

    A framework for deriving equations of motion for constrained quantum systems is introduced and a procedure for its implementation is outlined. In special cases, the proposed new method, which takes advantage of the fact that the space of pure states in quantum mechanics has both a symplectic structure and a metric structure, reduces to a quantum analogue of the Dirac theory of constraints in classical mechanics. Explicit examples involving spin-1/2 particles are worked out in detail: in the first example, our approach coincides with a quantum version of the Dirac formalism, while the second example illustrates how a situation that cannot be treated by Dirac's approach can nevertheless be dealt with in the present scheme.

  6. Metrics for Business Process Models

    Science.gov (United States)

    Mendling, Jan

    Up until now, there has been little research on why people introduce errors in real-world business process models. In a more general context, Simon [404] points to the limitations of cognitive capabilities and concludes that humans act rationally only to a certain extent. Concerning modeling errors, this argument would imply that human modelers lose track of the interrelations of large and complex models due to their limited cognitive capabilities and introduce errors that they would not insert in a small model. A recent study by Mendling et al. [275] explores in how far certain complexity metrics of business process models have the potential to serve as error determinants. The authors conclude that complexity indeed appears to have an impact on error probability. Before we can test such a hypothesis in a more general setting, we have to establish an understanding of how we can define determinants that drive error probability and how we can measure them.

  7. The effect of inlet conditions on the air side hydraulic resistance and flow maldistribution in industrial air heaters

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann-Vocke, Jonas, E-mail: jh63@waikato.ac.nz [University of Waikato, Energy Research Group, School of Science and Engineering, Private Bag 3105, Hamilton 3240 (New Zealand); Neale, James, E-mail: jamesn@waikato.ac.nz [University of Waikato, Energy Research Group, School of Science and Engineering, Private Bag 3105, Hamilton 3240 (New Zealand); Walmsley, Michael, E-mail: walmsley@waikato.ac.nz [University of Waikato, Department of Engineering, School of Science and Engineering, Private Bag 3105, Hamilton 3240 (New Zealand)

    2011-08-15

    Highlights: > Measured the effects of air heater inlet header geometry on hydraulic performance. > Measured the effects of inlet header flow maldistribution on hydraulic performance. > Inlet header flow maldistribution increases air heater system hydraulic resistance. - Abstract: Experimental system hydraulic resistance measurements on a scale air heater unit have highlighted the excessive hydraulic resistance of typical industry configurations. Both poor header inlet conditions and large header expansion angles are shown to contribute to system hydraulic resistance magnitudes 20-100% higher than suitable benchmark cases. Typical centrifugal fan system efficiencies well under 80% multiply the system resistance effects resulting in larger fan power penalties. Velocity profile measurements taken upstream and downstream of the test heat exchanger under flow maldistribution conditions provide insight into the flow maldistribution spreading caused by the heat exchanger resistance. The anisotropic resistance of the plate fin-and-tube heat exchanger is shown to result in resistance induced flow dispersion being concentrated in the axis parallel to the plate fins.

  8. Active Metric Learning for Supervised Classification

    OpenAIRE

    Kumaran, Krishnan; Papageorgiou, Dimitri; Chang, Yutong; Li, Minhan; Takáč, Martin

    2018-01-01

    Clustering and classification critically rely on distance metrics that provide meaningful comparisons between data points. We present mixed-integer optimization approaches to find optimal distance metrics that generalize the Mahalanobis metric extensively studied in the literature. Additionally, we generalize and improve upon leading methods by removing reliance on pre-designated "target neighbors," "triplets," and "similarity pairs." Another salient feature of our method is its ability to en...

  9. On Nakhleh's metric for reduced phylogenetic networks

    OpenAIRE

    Cardona, Gabriel; Llabrés, Mercè; Rosselló, Francesc; Valiente Feruglio, Gabriel Alejandro

    2009-01-01

    We prove that Nakhleh’s metric for reduced phylogenetic networks is also a metric on the classes of tree-child phylogenetic networks, semibinary tree-sibling time consistent phylogenetic networks, and multilabeled phylogenetic trees. We also prove that it separates distinguishable phylogenetic networks. In this way, it becomes the strongest dissimilarity measure for phylogenetic networks available so far. Furthermore, we propose a generalization of that metric that separates arbitrary phyl...

  10. Generalized tolerance sensitivity and DEA metric sensitivity

    OpenAIRE

    Neralić, Luka; E. Wendell, Richard

    2015-01-01

    This paper considers the relationship between Tolerance sensitivity analysis in optimization and metric sensitivity analysis in Data Envelopment Analysis (DEA). Herein, we extend the results on the generalized Tolerance framework proposed by Wendell and Chen and show how this framework includes DEA metric sensitivity as a special case. Further, we note how recent results in Tolerance sensitivity suggest some possible extensions of the results in DEA metric sensitivity.

  11. The definitive guide to IT service metrics

    CERN Document Server

    McWhirter, Kurt

    2012-01-01

    Used just as they are, the metrics in this book will bring many benefits to both the IT department and the business as a whole. Details of the attributes of each metric are given, enabling you to make the right choices for your business. You may prefer and are encouraged to design and create your own metrics to bring even more value to your business - this book will show you how to do this, too.

  12. Generalized tolerance sensitivity and DEA metric sensitivity

    Directory of Open Access Journals (Sweden)

    Luka Neralić

    2015-03-01

    Full Text Available This paper considers the relationship between Tolerance sensitivity analysis in optimization and metric sensitivity analysis in Data Envelopment Analysis (DEA. Herein, we extend the results on the generalized Tolerance framework proposed by Wendell and Chen and show how this framework includes DEA metric sensitivity as a special case. Further, we note how recent results in Tolerance sensitivity suggest some possible extensions of the results in DEA metric sensitivity.

  13. Common Metrics for Human-Robot Interaction

    Science.gov (United States)

    Steinfeld, Aaron; Lewis, Michael; Fong, Terrence; Scholtz, Jean; Schultz, Alan; Kaber, David; Goodrich, Michael

    2006-01-01

    This paper describes an effort to identify common metrics for task-oriented human-robot interaction (HRI). We begin by discussing the need for a toolkit of HRI metrics. We then describe the framework of our work and identify important biasing factors that must be taken into consideration. Finally, we present suggested common metrics for standardization and a case study. Preparation of a larger, more detailed toolkit is in progress.

  14. Chaotic inflation with metric and matter perturbations

    International Nuclear Information System (INIS)

    Feldman, H.A.; Brandenberger, R.H.

    1989-01-01

    A perturbative scheme to analyze the evolution of both metric and scalar field perturbations in an expanding universe is developed. The scheme is applied to study chaotic inflation with initial metric and scalar field perturbations present. It is shown that initial gravitational perturbations with wavelength smaller than the Hubble radius rapidly decay. The metric simultaneously picks up small perturbations determined by the matter inhomogeneities. Both are frozen in once the wavelength exceeds the Hubble radius. (orig.)

  15. Gravitational lensing in metric theories of gravity

    International Nuclear Information System (INIS)

    Sereno, Mauro

    2003-01-01

    Gravitational lensing in metric theories of gravity is discussed. I introduce a generalized approximate metric element, inclusive of both post-post-Newtonian contributions and a gravitomagnetic field. Following Fermat's principle and standard hypotheses, I derive the time delay function and deflection angle caused by an isolated mass distribution. Several astrophysical systems are considered. In most of the cases, the gravitomagnetic correction offers the best perspectives for an observational detection. Actual measurements distinguish only marginally different metric theories from each other

  16. The effects of nonlinear resistance and aerobic interval training on serum levels of apelin and insulin resistance in middle-aged obese men

    Directory of Open Access Journals (Sweden)

    Mahmoud Nikseresht

    2015-08-01

    Conclusion: The practical applications indicate that obese men can use both AIT and NRT exercise programs to reduce insulin resistance. However, the AIT may have better beneficial effects (as indicated by apelin-13 compared to NRT.

  17. Effect of resistance training on headache symptoms in adults

    DEFF Research Database (Denmark)

    Andersen, C. H.; Jensen, R. H.; Dalager, T.

    2017-01-01

    BACKGROUND: While strength training for the neck and shoulder muscles may be effective in reducing headache, the optimal combination of exercise frequency and duration is unknown. This study investigates the effect of different time-wise combinations of one weekly hour of strength training for th...

  18. Effects of electron irradiation on the resistive behaviour of YBCO-type ceramics

    International Nuclear Information System (INIS)

    Galatanu, A.; Novac, A.; Mosteanu, T.; Magureanu, M.

    1998-01-01

    YBCO-123 ceramic samples were irradiated with electron beams (E=0.5 MeV), the particle fluxes ranging between 10 15 and 10 19 e - /cm 2 . The induced structure modifications are analyzed through X-ray diffraction and their effects on the resistive behaviour are estimated. It is shown that a direct correlation can be established between the irradiation effects, oxygen disorder and hence the modification of the sample resistivity. A particular attention is given to the effects on the fluctuation mechanism arising near the transition temperature. (authors)

  19. Antimicrobial Effects of β-Lactams on Imipenem-Resistant Ceftazidime-Susceptible Pseudomonas aeruginosa.

    Science.gov (United States)

    Wi, Yu Mi; Choi, Ji-Young; Lee, Ji-Young; Kang, Cheol-In; Chung, Doo Ryeon; Peck, Kyong Ran; Song, Jae-Hoon; Ko, Kwan Soo

    2017-06-01

    We studied the resistance mechanism and antimicrobial effects of β-lactams on imipenem-resistant Pseudomonas aeruginosa isolates that were susceptible to ceftazidime as detected by time-kill curve methods. Among 215 P. aeruginosa isolates from hospitalized patients in eight hospitals in the Republic of Korea, 18 isolates (23.4% of 77 imipenem-resistant isolates) were imipenem resistant and ceftazidime susceptible. Multilocus sequence typing revealed diverse genotypes, which indicated independent emergence. These 18 isolates were negative for carbapenemase genes. All 18 imipenem-resistant ceftazidime-susceptible isolates showed decreased mRNA expression of oprD , and overexpression of mexB was observed in 13 isolates. In contrast, overexpression of ampC , mexD , mexF , or mexY was rarely found. Time-kill curve methods were applied to three selected imipenem-resistant ceftazidime-susceptible isolates at a standard inoculum (5 × 10 5 CFU/ml) or at a high inoculum (5 × 10 7 CFU/ml) to evaluate the antimicrobial effects of β-lactams. Inoculum effects were detected for all three β-lactam antibiotics, ceftazidime, cefepime, and piperacillin-tazobactam, against all three isolates. The antibiotics had significant killing effects in the standard inoculum, but no effects in the high inoculum were observed. Our results suggest that β-lactam antibiotics should be used with caution in patients with imipenem-resistant ceftazidime-susceptible P. aeruginosa infection, especially in high-inoculum infections such as endocarditis and osteomyelitis. Copyright © 2017 American Society for Microbiology.

  20. About the possibility of a generalized metric

    International Nuclear Information System (INIS)

    Lukacs, B.; Ladik, J.

    1991-10-01

    The metric (the structure of the space-time) may be dependent on the properties of the object measuring it. The case of size dependence of the metric was examined. For this dependence the simplest possible form of the metric tensor has been constructed which fulfils the following requirements: there be two extremal characteristic scales; the metric be unique and the usual between them; the change be sudden in the neighbourhood of these scales; the size of the human body appear as a parameter (postulated on the basis of some philosophical arguments). Estimates have been made for the two extremal length scales according to existing observations. (author) 19 refs

  1. Effect of Microstructure and Environment on Static Crack Growth Resistance in Alloy 706

    Science.gov (United States)

    Yang, Ling; Hawk, Jeffrey A.; Duquette, David J.; Schwant, Robin C.

    2009-06-01

    The relationship between thermo-mechanical processing, resultant microstructure, and mechanical properties has been of interest in the field of metallurgy for centuries. In this work, the effect of heat treatment on microstructure and key mechanical properties important for turbine rotor design has been investigated. Specifically, the tensile yield strength and crack growth resistance for a nickel-iron based superalloy 706 has been examined. Through a systematic study, a correlation was found between the processing parameters and the microstructure. Specifically, differences in grain boundary and grain interior precipitates were identified and correlated with processing conditions. Further, a strong relationship between microstructure and mechanical properties was identified. The type and orientation of grain boundary precipitates affect time-dependent crack propagation resistance, and the size and volume fraction of grain interior precipitates were correlated with tensile yield strength. It was also found that there is a strong environmental effect on time-dependent crack propagation resistance, and the sensitivity to environmental damage is microstructure dependent. Microstructures with η decorated grain boundaries were more resistant to environmental damage through oxygen embrittlement than microstructures with no η phase on the grain boundaries. An effort was made to explore the mechanisms of improving the time-dependent crack propagation resistance through thermo-mechanical processing, and several mechanisms were identified in both the environment-dependent and the environment-independent category. These mechanisms were ranked based on their contributions to crack propagation resistance.

  2. Effect of psychological capital and resistance to change on organisational citizenship behaviour

    Directory of Open Access Journals (Sweden)

    Loyd Beal III

    2013-09-01

    Research purpose: This study examined the possible role of resistance to change as a moderator of the predictive relationship between PsyCap and organisational citizenship behaviour (OCB, in which OCB served as an index for measuring positive organisational change. Motivation for the study: Little empirical research has investigated the application of positive organisational behaviour to government organisations undergoing organisational change. Organisations can use the study results to increase positive outcomes and reduce resistance in government organisations experiencing a holistic change intervention. Research design, approach and method: The data comprised a cross-sectional survey of 97 employees from a government organisation that provides life-cycle career management support. Employees completed the 24-item psychological capital questionnaire, the 16-item organisational citizenship behaviour scale and the 17-item resistance to change scale. Data analyses used a mixed methods approach to merge quantitative inferential statistics with qualitative thematic analysis. Main findings: The quantitative analysis yielded high levels of resistance to change that moderated the positive effect of PsyCap on organisational citizenship behaviour. The thematic analysis revealed that affective, behavioural and cognitive forms of resistance to change were prevalent. Practical/managerial implications: Organisational leaders should seek to reduce resistance and increase the resources that organisations need to effect positive organisational change. Contribution/value-add: This study adds to the growing body of knowledge about positive organisational behaviour in government organisations.

  3. Mechanism and degree of chemical elements effect on atmosphere corrosion resistance of steels

    International Nuclear Information System (INIS)

    Vu Din' Vuj

    1991-01-01

    It follows from the proposed regression equations that falourable effect of chemical elements on steel resistance to atmospheric corrosion is determined by their ability to increase interatom bond stability in iron crystal lattice and form corrosion products with high protection properties. Element positive influence on steel corrosion resistance decreases in the following order: S, P, Si, Mn, Cu, Cr, Ni, C in semiurban tropical atmosphere and S, Mn, Sr, Cu, Ni, Cr in coastal atmosphere. In the latter case C increases corrosion in a greater degree as compared to P. Small ammounts of Mo decrease steel resistance in semiurban atmosphere and almost do not influence it in the coastal one. Possible mechanisms of individual element influence on steel corrosion resistance are considered

  4. Effect of methylxanthines derived from pentoxifylline on P-glycoprotein mediated multidrug resistance

    International Nuclear Information System (INIS)

    Kupsakova, I.; Drobna, Z.; Breier, A.

    2001-01-01

    In this paper study of multidrug resistance (MDR) antitumor agents - P-glycoprotein (PGP) is presented. The ability of pentoxifylline (PTX) to depress resistance mediated by overexpression of PGP in mouse leukemic cell line L 121 ONCR resistant to vincristine (VCR) was described earlier. PTX depressed the resistance of these cells in a dose and time dependent manner. This effect was accompanied by increased level of [ 3 H]-vincristine accumulation by these cells. The methylxanthines with different length of this aliphatic side chain were synthesized and their capability to depress MDR was tested. The results indicated that the position of carbonyl group plays a crucial role for the ability of the derivative to depress MDR of L 121 ONCR cells. (authors)

  5. Effect of cold working on the stress corrosion cracking resistance of nickel-chromium-iron alloys

    International Nuclear Information System (INIS)

    Yonezawa, T.; Onimura, K.

    1987-01-01

    In order to grasp the stress corrosion cracking resistance of cold worked nickel base alloys in PWR primary water, the effect of cold working on the stress corrosion cracking resistance of alloys 600, X-750 and 690, in high temperature water, have been studied. Stress corrosion cracking tests were conducted at 360 0 C (633K) in a simulated PWR primary water for about 12,000 hours (43.2Ms). From the test results, it is concluded that the stress corrosion cracking resistance in the cold worked Alloy 600 at the same applied stress level increases with an increase in cold working ratio, and the cold worked alloys of thermally treated 690 and X-750 have excellent stress corrosion cracking resistance. (Author)

  6. Designing Base and Subbase to Resist Environmental Effects on Pavements

    Science.gov (United States)

    2018-02-02

    MnDOTs current pavement thickness design procedures do not characterize the effects of subgrade soil frost susceptibility. Previous research indicates frost action is the most severe environmental factor on pavement performance. The most accepted ...

  7. Effect of Vibration on Bacterial Growth and Antibiotic Resistance

    Science.gov (United States)

    Juergensmeyer, Elizabeth A.; Juergensmeyer, Margaret A.

    2004-01-01

    The purpose of this research grant was to provide a fundamental, systematic investigation of the effects of oscillatory acceleration on bacterial proliferation and their responses to antibiotics in a liquid medium.

  8. Investigation of Resistance to Mechanical Effect of Braille Formed on Different Materials

    Directory of Open Access Journals (Sweden)

    Ingrida VENYTĖ

    2014-06-01

    Full Text Available Qualitative analysis of stresses emerged in paperboard during Braille embossing, using specialized polarimetric equipment, was carried out. Resistance to mechanical effect of Braille dot surfaces, formed with different printing types on different materials (paper, paperboard, polymer, textile, Al foil was investigated. It was determined that Braille dot height change after period mechanical effect is different.

  9. Pleotropic effects of leptin to reverse insulin resistance and diabetic ketoacidosis

    DEFF Research Database (Denmark)

    Perry, Rachel J; Petersen, Kitt Falk; Shulman, Gerald I.

    2016-01-01

    In this review we discuss the mechanisms for the pleotropic effects of leptin replacement therapy to reverse liver and muscle insulin resistance in lipodystrophic individuals, as well as insulin-independent effects of leptin replacement therapy to suppress white adipose tissue lipolysis, hepatic...

  10. Cost-effectiveness of renal denervation therapy for the treatment of resistant hypertension in the Netherlands

    NARCIS (Netherlands)

    Henry, Thea L.; De Brouwer, Bonnie F E; Van Keep, Marjolijn M L; Blankestijn, Peter J.; Bots, Michiel L.; Koffijberg, Hendrik

    2015-01-01

    Objectives: Safety and efficacy data for catheter-based renal denervation (RDN) in the treatment of resistant hypertension have been used to estimate the cost-effectiveness of this approach. However, there are no Dutch-specific analyses. This study examined the cost-effectiveness of RDN from the

  11. Effect of the ferrule on fracture resistance of teeth restored with ...

    African Journals Online (AJOL)

    However few studies have considered the effect of different ferrule designs on prefabricated post and composite core systems. Aim: This study investigated the effect of different ferrule designs on the fracture resistance of teeth incorporating prefabricated posts and composite cores. It also assessed the necessity of a post in ...

  12. Metrics for measuring net-centric data strategy implementation

    Science.gov (United States)

    Kroculick, Joseph B.

    2010-04-01

    An enterprise data strategy outlines an organization's vision and objectives for improved collection and use of data. We propose generic metrics and quantifiable measures for each of the DoD Net-Centric Data Strategy (NCDS) data goals. Data strategy metrics can be adapted to the business processes of an enterprise and the needs of stakeholders in leveraging the organization's data assets to provide for more effective decision making. Generic metrics are applied to a specific application where logistics supply and transportation data is integrated across multiple functional groups. A dashboard presents a multidimensional view of the current progress to a state where logistics data shared in a timely and seamless manner among users, applications, and systems.

  13. Eye Tracking Metrics for Workload Estimation in Flight Deck Operation

    Science.gov (United States)

    Ellis, Kyle; Schnell, Thomas

    2010-01-01

    Flight decks of the future are being enhanced through improved avionics that adapt to both aircraft and operator state. Eye tracking allows for non-invasive analysis of pilot eye movements, from which a set of metrics can be derived to effectively and reliably characterize workload. This research identifies eye tracking metrics that correlate to aircraft automation conditions, and identifies the correlation of pilot workload to the same automation conditions. Saccade length was used as an indirect index of pilot workload: Pilots in the fully automated condition were observed to have on average, larger saccadic movements in contrast to the guidance and manual flight conditions. The data set itself also provides a general model of human eye movement behavior and so ostensibly visual attention distribution in the cockpit for approach to land tasks with various levels of automation, by means of the same metrics used for workload algorithm development.

  14. Value-based metrics and Internet-based enterprises

    Science.gov (United States)

    Gupta, Krishan M.

    2001-10-01

    Within the last few years, a host of value-based metrics like EVA, MVA, TBR, CFORI, and TSR have evolved. This paper attempts to analyze the validity and applicability of EVA and Balanced Scorecard for Internet based organizations. Despite the collapse of the dot-com model, the firms engaged in e- commerce continue to struggle to find new ways to account for customer-base, technology, employees, knowledge, etc, as part of the value of the firm. While some metrics, like the Balance Scorecard are geared towards internal use, others like EVA are for external use. Value-based metrics are used for performing internal audits as well as comparing firms against one another; and can also be effectively utilized by individuals outside the firm looking to determine if the firm is creating value for its stakeholders.

  15. Method Points: towards a metric for method complexity

    Directory of Open Access Journals (Sweden)

    Graham McLeod

    1998-11-01

    Full Text Available A metric for method complexity is proposed as an aid to choosing between competing methods, as well as in validating the effects of method integration or the products of method engineering work. It is based upon a generic method representation model previously developed by the author and adaptation of concepts used in the popular Function Point metric for system size. The proposed technique is illustrated by comparing two popular I.E. deliverables with counterparts in the object oriented Unified Modeling Language (UML. The paper recommends ways to improve the practical adoption of new methods.

  16. Direct and Pollinator-Mediated Effects of Herbivory on Strawberry and the Potential for Improved Resistance

    Directory of Open Access Journals (Sweden)

    Anne Muola

    2017-05-01

    Full Text Available The global decline in pollinators has partly been blamed on pesticides, leading some to propose pesticide-free farming as an option to improve pollination. However, herbivores are likely to be more prevalent in pesticide-free environments, requiring knowledge of their effects on pollinators, and alternative crop protection strategies to mitigate any potential pollination reduction. Strawberry leaf beetles (SLB Galerucella spp. are important strawberry pests in Northern Europe and Russia. Given that SLB attack both leaf and flower tissue, we hypothesized pollinators would discriminate against SLB-damaged strawberry plants (Fragaria vesca, cultivar ‘Rügen’, leading to lower pollination success and yield. In addition we screened the most common commercial cultivar ‘Rügen’ and wild Swedish F. vesca genotypes for SLB resistance to assess the potential for inverse breeding to restore high SLB resistance in cultivated strawberry. Behavioral observations in a controlled experiment revealed that the local pollinator fauna avoided strawberry flowers with SLB-damaged petals. Low pollination, in turn, resulted in smaller more deformed fruits. Furthermore, SLB-damaged flowers produced smaller fruits even when they were hand pollinated, showing herbivore damage also had direct effects on yield, independent of indirect effects on pollination. We found variable resistance in wild woodland strawberry to SLB and more resistant plant genotypes than the cultivar ‘Rügen’ were identified. Efficient integrated pest management strategies should be employed to mitigate both direct and indirect effects of herbivory for cultivated strawberry, including high intrinsic plant resistance.

  17. Nonlinear Semi-Supervised Metric Learning Via Multiple Kernels and Local Topology.

    Science.gov (United States)

    Li, Xin; Bai, Yanqin; Peng, Yaxin; Du, Shaoyi; Ying, Shihui

    2018-03-01

    Changing the metric on the data may change the data distribution, hence a good distance metric can promote the performance of learning algorithm. In this paper, we address the semi-supervised distance metric learning (ML) problem to obtain the best nonlinear metric for the data. First, we describe the nonlinear metric by the multiple kernel representation. By this approach, we project the data into a high dimensional space, where the data can be well represented by linear ML. Then, we reformulate the linear ML by a minimization problem on the positive definite matrix group. Finally, we develop a two-step algorithm for solving this model and design an intrinsic steepest descent algorithm to learn the positive definite metric matrix. Experimental results validate that our proposed method is effective and outperforms several state-of-the-art ML methods.

  18. Is electroconvulsive therapy effective as augmentation in clozapine-resistant schizophrenia?

    Science.gov (United States)

    Kittsteiner Manubens, Lucas; Lobos Urbina, Diego; Aceituno, David

    2016-10-14

    Clozapine is considered to be the most effective antipsychotic drug for patients with treatment resistant schizophrenia, but up to a third of the patients do not respond to this treatment. Various strategies have been tried to augment the effect of clozapine in non-responders, one of these strategies being electroconvulsive therapy. However, its efficacy and safety are not yet clear. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified six systematic reviews including 55 studies, among them six randomized controlled trials addressing clozapine-resistant schizophrenia. We combined the evidence using meta-analysis and generated a summary of findings following the GRADE approach. We concluded electroconvulsive therapy probably augments response to clozapine in patients with treatment resistant schizophrenia, but it is not possible to determine if it leads to cognitive adverse effects because the certainty of the evidence is very low.

  19. Effect of Circuit Breaker Shunt Resistance on Chaotic Ferroresonance in Voltage Transformer

    Directory of Open Access Journals (Sweden)

    RADMANESH, H.

    2010-08-01

    Full Text Available Ferroresonance or nonlinear resonance is a complex electrical phenomenon, which may cause over voltages and over currents in the electrical power system which endangers the system reliability and continuous safe operating. This paper studies the effect of circuit breaker shunt resistance on the control of chaotic ferroresonance in a voltage transformer. It is expected that this resistance generally can cause ferroresonance dropout. For confirmation this aspect Simulation has been done on a one phase voltage transformer rated 100VA, 275kV. The magnetization characteristic of the transformer is modeled by a single-value two-term polynomial with q=7. The simulation results reveal that considering the shunt resistance on the circuit breaker, exhibits a great mitigating effect on ferroresonance over voltages. Significant effect on the onset of chaos, the range of parameter values that may lead to chaos along with ferroresonance voltages has been obtained and presented.

  20. effect of biocides on biofilms of some multidrug resistant clinical ...

    African Journals Online (AJOL)

    userpc

    They are used on medical devices to limit contamination. This study investigated the effects of some ... The antibiotic sensitivity test of the isolates was done following the Kirby-Bauer disc .... Table 1: Antimicrobial susceptibility profile of bacterial isolates from various clinicalspecimens in. Yola, Nigeria. Bacterial Isolates. CPX.

  1. The Articulatory In-Out Effect Resists Oral Motor Interference

    Science.gov (United States)

    Lindau, Berit; Topolinski, Sascha

    2018-01-01

    People prefer words with inward directed consonantal patterns (e.g., MENIKA) compared to outward patterns (KENIMA), because inward (outward) articulation movements resemble positive (negative) mouth actions such as swallowing (spitting). This effect might rely on covert articulation simulations, or subvocalizations, since it occurs also under…

  2. Peak effect in surface resistance at microwave frequencies in Dy ...

    Indian Academy of Sciences (India)

    In the measurements at both frequencies the induced microwave current was always less than the critical current of the films. The reason for observation of this peak effect in these films has been explained in our earlier publication [5]. Comparing figures 1 and 2, it is observed that the peaks in sample S1 are broader and.

  3. The Effect of Tensile Hysteresis and Contact Resistance on the Performance of Strain-Resistant Elastic-Conductive Webbing

    Directory of Open Access Journals (Sweden)

    Tien-Wei Shyr

    2011-01-01

    Full Text Available To use e-textiles as a strain-resistance sensor they need to be both elastic and conductive. Three kinds of elastic-conductive webbings, including flat, tubular, and belt webbings, made of Lycra fiber and carbon coated polyamide fiber, were used in this study. The strain-resistance properties of the webbings were evaluated in stretch-recovery tests and measured within 30% strain. It was found that tensile hysteresis and contact resistance significantly influence the tensile elasticity and the resistance sensitivity of the webbings. The results showed that the webbing structure definitely contributes to the tensile hysteresis and contact resistance. The smaller the friction is among the yarns in the belt webbing, the smaller the tensile hysteresis loss. However the close proximity of the conductive yarns in flat and tubular webbings results in a lower contact resistance.

  4. Metabolic effects of resistance or high-intensity interval training among glycemic control-nonresponsive children with insulin resistance.

    Science.gov (United States)

    Álvarez, C; Ramírez-Campillo, R; Ramírez-Vélez, R; Martínez, C; Castro-Sepúlveda, M; Alonso-Martínez, A; Izquierdo, M

    2018-01-01

    Little evidence exists on which variables of body composition or muscular strength mediates more glucose control improvements taking into account inter-individual metabolic variability to different modes of exercise training. We examined 'mediators' to the effects of 6-weeks of resistance training (RT) or high-intensity interval training (HIT) on glucose control parameters in physically inactive schoolchildren with insulin resistance (IR). Second, we also determined both training-induce changes and the prevalence of responders (R) and non-responders (NR) to decrease the IR level. Fifty-six physically inactive children diagnosed with IR followed a RT or supervised HIT program for 6 weeks. Participants were classified based on ΔHOMA-IR into glycemic control R (decrease in homeostasis model assessment-IR (HOMA-IR) training-induced changes to glucose control parameters; and third the report of R and NR to improve body composition, cardiovascular, metabolic and performance variables. Mediation analysis revealed that improvements (decreases) in abdominal fat by the waist circumference can explain more the effects (decreases) of HOMA-IR in physically inactive schoolchildren under RT or HIT regimes. The same analysis showed that increased one-maximum repetition leg-extension was correlated with the change in HOMA-IR (β=-0.058; P=0.049). Furthermore, a change in the waist circumference fully mediated the dose-response relationship between changes in the leg-extension strength and HOMA-IR (β'=-0.004; P=0.178). RT or HIT were associated with significant improvements in body composition, muscular strength, blood pressure and cardiometabolic parameters irrespective of improvement in glycemic control response. Both glucose control RT-R and HIT-R (respectively), had significant improvements in mean HOMA-IR, mean muscular strength leg-extension and mean measures of adiposity. The improvements in the lower body strength and the decreases in waist circumference can explain more

  5. Influence of Musical Enculturation on Brain Responses to Metric Deviants

    Directory of Open Access Journals (Sweden)

    Niels T. Haumann

    2018-04-01

    Full Text Available The ability to recognize metric accents is fundamental in both music and language perception. It has been suggested that music listeners prefer rhythms that follow simple binary meters, which are common in Western music. This means that listeners expect odd-numbered beats to be strong and even-numbered beats to be weak. In support of this, studies have shown that listeners exposed to Western music show stronger novelty and incongruity related P3 and irregularity detection related mismatch negativity (MMN brain responses to attenuated odd- than attenuated even-numbered metric positions. Furthermore, behavioral evidence suggests that music listeners' preferences can be changed by long-term exposure to non-Western rhythms and meters, e.g., by listening to African or Balkan music. In our study, we investigated whether it might be possible to measure effects of music enculturation on neural responses to attenuated tones on specific metric positions. We compared the magnetic mismatch negativity (MMNm to attenuated beats in a “Western group” of listeners (n = 12 mainly exposed to Western music and a “Bicultural group” of listeners (n = 13 exposed for at least 1 year to both Sub-Saharan African music in addition to Western music. We found that in the “Western group” the MMNm was higher in amplitude to deviant tones on odd compared to even metric positions, but not in the “Bicultural group.” In support of this finding, there was also a trend of the “Western group” to rate omitted beats as more surprising on odd than even metric positions, whereas the “Bicultural group” seemed to discriminate less between metric positions in terms of surprise ratings. Also, we observed that the overall latency of the MMNm was significantly shorter in the Bicultural group compared to the Western group. These effects were not biased by possible differences in rhythm perception ability or music training, measured with the Musical Ear Test (MET

  6. Influence of Musical Enculturation on Brain Responses to Metric Deviants.

    Science.gov (United States)

    Haumann, Niels T; Vuust, Peter; Bertelsen, Freja; Garza-Villarreal, Eduardo A

    2018-01-01

    The ability to recognize metric accents is fundamental in both music and language perception. It has been suggested that music listeners prefer rhythms that follow simple binary meters, which are common in Western music. This means that listeners expect odd-numbered beats to be strong and even-numbered beats to be weak. In support of this, studies have shown that listeners exposed to Western music show stronger novelty and incongruity related P3 and irregularity detection related mismatch negativity (MMN) brain responses to attenuated odd- than attenuated even-numbered metric positions. Furthermore, behavioral evidence suggests that music listeners' preferences can be changed by long-term exposure to non-Western rhythms and meters, e.g., by listening to African or Balkan music. In our study, we investigated whether it might be possible to measure effects of music enculturation on neural responses to attenuated tones on specific metric positions. We compared the magnetic mismatch negativity (MMNm) to attenuated beats in a "Western group" of listeners ( n = 12) mainly exposed to Western music and a "Bicultural group" of listeners ( n = 13) exposed for at least 1 year to both Sub-Saharan African music in addition to Western music. We found that in the "Western group" the MMNm was higher in amplitude to deviant tones on odd compared to even metric positions, but not in the "Bicultural group." In support of this finding, there was also a trend of the "Western group" to rate omitted beats as more surprising on odd than even metric positions, whereas the "Bicultural group" seemed to discriminate less between metric positions in terms of surprise ratings. Also, we observed that the overall latency of the MMNm was significantly shorter in the Bicultural group compared to the Western group. These effects were not biased by possible differences in rhythm perception ability or music training, measured with the Musical Ear Test (MET). Furthermore, source localization analyses

  7. A weighted coupling metric for business process models

    NARCIS (Netherlands)

    Vanderfeesten, I.T.P.; Cardoso, J.; Reijers, H.A.; Eder, J.; Tomassen, S.L.; Opdahl, A.; Sindre, G.

    2007-01-01

    Various efforts recently aimed at the development of quality metrics for process models. In this paper, we propose a new notion of coupling, which has been used successfully in software engineering for many years. It extends other work by specifically incorporating the effects of different types of

  8. Metric approach for sound propagation in nematic liquid crystals

    Science.gov (United States)

    Pereira, E.; Fumeron, S.; Moraes, F.

    2013-02-01

    In the eikonal approach, we describe sound propagation near topological defects of nematic liquid crystals as geodesics of a non-Euclidian manifold endowed with an effective metric tensor. The relation between the acoustics of the medium and this geometrical description is given by Fermat's principle. We calculate the ray trajectories and propose a diffraction experiment to retrieve information about the elastic constants.

  9. Effect of MTA and Portland Cement on Fracture Resistance of Dentin

    Directory of Open Access Journals (Sweden)

    Maryam Forghani

    2013-06-01

    Full Text Available Background and aims. It is important to evaluate the effects of endodontic materials on tooth structures to avoid endodontic treatment failure. The aim of the present study was to investigate the effect of mineral trioxide aggregates (MTA and Portland cement (PC on fracture resistance of dentin. Materials and methods. Thirty-six freshly extracted human single-rooted premolar teeth were selected. The crowns were removed and the roots were randomly divided into two experimental groups and one control group. The root samples were longitudinally divided into two halves and a dentin bar (2×2×10 mm was cut from each root section for short-term (2 weeks and long-term (12 weeks evaluations. The root sections in the experimental groups were exposed to MTA or PC, while keeping the control group specimens in physiologic saline. The fracture resistance of each specimen was measured using an Instron testing machine. The results were statistically analyzed using ANOVA, a post hoc Tukey test and paired ttest at 5% significance level. Results. The fracture resistance of MTA-treated specimens significantly increased between 2 and 12 weeks (P0.05. Conclusion. The results showed that MTA increased the fracture resistance of root dentin, while PC had no significant effect on dentin fracture resistance.

  10. Insulin Sensitivity Determines Effects of Insulin and Meal Ingestion on Systemic Vascular Resistance in Healthy Subjects.

    Science.gov (United States)

    Woerdeman, Jorn; Meijer, Rick I; Eringa, Etto C; Hoekstra, Trynke; Smulders, Yvo M; Serné, Erik H

    2016-01-01

    In addition to insulin's metabolic actions, insulin can dilate arterioles which increase blood flow to metabolically active tissues. This effect is blunted in insulin-resistant subjects. Insulin's effect on SVR, determined by resistance arterioles, has, however, rarely been examined directly. We determined the effects of both hyperinsulinemia and a mixed meal on SVR and its relationship with insulin sensitivity. Thirty-seven lean and obese women underwent a hyperinsulinemic-euglycemic clamp, and 24 obese volunteers underwent a mixed-meal test. SVR was assessed using CPP before and during hyperinsulinemia as well as before and 60 and 120 minutes after a meal. SVR decreased significantly during hyperinsulinemia (-13%; p Insulin decreased SVR more strongly in insulin-sensitive individuals (standardized β: -0.44; p = 0.01). In addition, SVR at 60 minutes after meal ingestion was inversely related to the Matsuda index (β: -0.39; p = 0.04) and the change in postprandial SVR was directly related to postprandial glycemia (β: 0.53; p insulin resistance. This suggests that resistance to insulin-induced vasodilatation contributes to regulation of vascular resistance. © 2015 John Wiley & Sons Ltd.

  11. Effect of swift heavy ion irradiation on surface resistance of ...

    Indian Academy of Sciences (India)

    ... Larkin–Ovchinnikov scenario [5] where the effective pinning force on the FLL is given by BJc(H)=(np〈 f 2〉/Vc)1/2 where np is the density of pinning centers, f the ele- mentary pinning force parameter and Vc the Larkin volume over which the FLL maintains its spatial order. We have shown in an earlier communication [6] ...

  12. Recommendations for Methicillin-Resistant Staphylococcus aureus Prevention in Adult ICUs: A Cost-Effectiveness Analysis.

    Science.gov (United States)

    Whittington, Melanie D; Atherly, Adam J; Curtis, Donna J; Lindrooth, Richard C; Bradley, Cathy J; Campbell, Jonathan D

    2017-08-01

    Patients in the ICU are at the greatest risk of contracting healthcare-associated infections like methicillin-resistant Staphylococcus aureus. This study calculates the cost-effectiveness of methicillin-resistant S aureus prevention strategies and recommends specific strategies based on screening test implementation. A cost-effectiveness analysis using a Markov model from the hospital perspective was conducted to determine if the implementation costs of methicillin-resistant S aureus prevention strategies are justified by associated reductions in methicillin-resistant S aureus infections and improvements in quality-adjusted life years. Univariate and probabilistic sensitivity analyses determined the influence of input variation on the cost-effectiveness. ICU. Hypothetical cohort of adults admitted to the ICU. Three prevention strategies were evaluated, including universal decolonization, targeted decolonization, and screening and isolation. Because prevention strategies have a screening component, the screening test in the model was varied to reflect commonly used screening test categories, including conventional culture, chromogenic agar, and polymerase chain reaction. Universal and targeted decolonization are less costly and more effective than screening and isolation. This is consistent for all screening tests. When compared with targeted decolonization, universal decolonization is cost-saving to cost-effective, with maximum cost savings occurring when a hospital uses more expensive screening tests like polymerase chain reaction. Results were robust to sensitivity analyses. As compared with screening and isolation, the current standard practice in ICUs, targeted decolonization, and universal decolonization are less costly and more effective. This supports updating the standard practice to a decolonization approach.

  13. Gravitational Metric Tensor Exterior to Rotating Homogeneous ...

    African Journals Online (AJOL)

    The covariant and contravariant metric tensors exterior to a homogeneous spherical body rotating uniformly about a common φ axis with constant angular velocity ω is constructed. The constructed metric tensors in this gravitational field have seven non-zero distinct components.The Lagrangian for this gravitational field is ...

  14. Invariant metric for nonlinear symplectic maps

    Indian Academy of Sciences (India)

    In this paper, we construct an invariant metric in the space of homogeneous polynomials of a given degree (≥ 3). The homogeneous polynomials specify a nonlinear symplectic map which in turn represents a Hamiltonian system. By minimizing the norm constructed out of this metric as a function of system parameters, we ...

  15. Finite Metric Spaces of Strictly negative Type

    DEFF Research Database (Denmark)

    Hjorth, Poul G.

    If a finite metric space is of strictly negative type then its transfinite diameter is uniquely realized by an infinite extent (“load vector''). Finite metric spaces that have this property include all trees, and all finite subspaces of Euclidean and Hyperbolic spaces. We prove that if the distance...

  16. Fixed point theory in metric type spaces

    CERN Document Server

    Agarwal, Ravi P; O’Regan, Donal; Roldán-López-de-Hierro, Antonio Francisco

    2015-01-01

    Written by a team of leading experts in the field, this volume presents a self-contained account of the theory, techniques and results in metric type spaces (in particular in G-metric spaces); that is, the text approaches this important area of fixed point analysis beginning from the basic ideas of metric space topology. The text is structured so that it leads the reader from preliminaries and historical notes on metric spaces (in particular G-metric spaces) and on mappings, to Banach type contraction theorems in metric type spaces, fixed point theory in partially ordered G-metric spaces, fixed point theory for expansive mappings in metric type spaces, generalizations, present results and techniques in a very general abstract setting and framework. Fixed point theory is one of the major research areas in nonlinear analysis. This is partly due to the fact that in many real world problems fixed point theory is the basic mathematical tool used to establish the existence of solutions to problems which arise natur...

  17. Metric solution of a spinning mass

    International Nuclear Information System (INIS)

    Sato, H.

    1982-01-01

    Studies on a particular class of asymptotically flat and stationary metric solutions called the Kerr-Tomimatsu-Sato class are reviewed about its derivation and properties. For a further study, an almost complete list of the papers worked on the Tomimatsu-Sato metrics is given. (Auth.)

  18. On Information Metrics for Spatial Coding.

    Science.gov (United States)

    Souza, Bryan C; Pavão, Rodrigo; Belchior, Hindiael; Tort, Adriano B L

    2018-04-01

    The hippocampal formation is involved in navigation, and its neuronal activity exhibits a variety of spatial correlates (e.g., place cells, grid cells). The quantification of the information encoded by spikes has been standard procedure to identify which cells have spatial correlates. For place cells, most of the established metrics derive from Shannon's mutual information (Shannon, 1948), and convey information rate in bits/s or bits/spike (Skaggs et al., 1993, 1996). Despite their widespread use, the performance of these metrics in relation to the original mutual information metric has never been investigated. In this work, using simulated and real data, we find that the current information metrics correlate less with the accuracy of spatial decoding than the original mutual information metric. We also find that the top informative cells may differ among metrics, and show a surrogate-based normalization that yields comparable spatial information estimates. Since different information metrics may identify different neuronal populations, we discuss current and alternative definitions of spatially informative cells, which affect the metric choice. Copyright © 2018 IBRO. Published by Elsevier Ltd. All rights reserved.

  19. Validation of Metrics for Collaborative Systems

    Directory of Open Access Journals (Sweden)

    Ion IVAN

    2008-01-01

    Full Text Available This paper describe the new concepts of collaborative systems metrics validation. The paper define the quality characteristics of collaborative systems. There are proposed a metric to estimate the quality level of collaborative systems. There are performed measurements of collaborative systems quality using a specially designed software.

  20. Validation of Metrics for Collaborative Systems

    OpenAIRE

    Ion IVAN; Cristian CIUREA

    2008-01-01

    This paper describe the new concepts of collaborative systems metrics validation. The paper define the quality characteristics of collaborative systems. There are proposed a metric to estimate the quality level of collaborative systems. There are performed measurements of collaborative systems quality using a specially designed software.

  1. Software Power Metric Model: An Implementation | Akwukwuma ...

    African Journals Online (AJOL)

    ... and the execution time (TIME) in each case was recorded. We then obtain the application functions point count. Our result shows that the proposed metric is computable, consistent in its use of unit, and is programming language independent. Keywords: Software attributes, Software power, measurement, Software metric, ...

  2. Effect of Contact Pressure on the Resistance Contact Value and Temperature Changes in Copper Busbar Connection

    Directory of Open Access Journals (Sweden)

    Agus Risdiyanto

    2012-12-01

    Full Text Available This paper discussed the influence of tightness or contacts pressure on copper busbar joints to determine changes in the value of the initial contact resistance and the maximum temperature at the joint due to high current load. The test sample was copper busbar 3 x 30 mm with configuration of bolted overlapping joint. Increasing contact pressure at the joint was measured to find out its effect on the value of contact resistance. The applied pressure was 6 to 36 MPa. Procedure of contact resistance measurement refer to the ASTM B539 standard using four-wire method. The sample subsequently loaded with the current of 350 A for 60 minutes and the maximum temperature at the joint was measured. The result showed that increasing contact pressure at the busbar joint will reduce the contact resistance and maximum temperature. The increase of contact pressure from 6 to 30 MPa causes decreasing contact resistance from 16 μΩ to 11 μΩ. Further increasing of contact pressure more than 30 MPa did not affect the contact resistance significantly. The lowest temperatur of busbar joint of 54°C was reached at a contact pressure of 36 Mpa.

  3. Study of prevalence and effects of insulin resistance in patients with chronic hepatitis C genotype 4.

    Science.gov (United States)

    Amer, A F; Baddour, M M; Elshazly, M A; Fadally, G; Hanafi, N F; Assar, S L

    2016-02-01

    There is strong epidemiological evidence linking hepatitis C virus (HCV) infection and diabetes. Our aim was to evaluate the prevalence of insulin resistance in Egyptian patients with chronic HCV genotype 4 infection, to assess factors associated with insulin resistance and to test the impact of insulin resistance on outcomes of treatment with pegylated interferon/ribavirin. Insulin resistance [homeostasis model assessmentinsulin resistance (HOMA-IR) score > 3.0] was detected in 31 of 100 nondiabetic patients. The relationship between elevated HOMA-IR and baseline viral load and degree of fibrosis was statistically significant (r = 0.218 and r = 0.223). Follow-up of patients with complete early virological response until the end of treatment showed a statistically significant decrease in HOMA-IR score. Out of 29 liver tissue sections examined, 14 had a low level of expression of insulin receptor type 1 by immunohistochemical studies. This study confirms that insulin resistance affects treatment outcome, and thus HOMA-IR testing before initiation of therapy may be a cost-effective tool.

  4. The role of contact resistance in graphene field-effect devices

    Science.gov (United States)

    Giubileo, Filippo; Di Bartolomeo, Antonio

    2017-08-01

    The extremely high carrier mobility and the unique band structure, make graphene very useful for field-effect transistor applications. According to several works, the primary limitation to graphene based transistor performance is not related to the material quality, but to extrinsic factors that affect the electronic transport properties. One of the most important parasitic element is the contact resistance appearing between graphene and the metal electrodes functioning as the source and the drain. Ohmic contacts to graphene, with low contact resistances, are necessary for injection and extraction of majority charge carriers to prevent transistor parameter fluctuations caused by variations of the contact resistance. The International Technology Roadmap for Semiconductors, toward integration and down-scaling of graphene electronic devices, identifies as a challenge the development of a CMOS compatible process that enables reproducible formation of low contact resistance. However, the contact resistance is still not well understood despite it is a crucial barrier towards further improvements. In this paper, we review the experimental and theoretical activity that in the last decade has been focusing on the reduction of the contact resistance in graphene transistors. We will summarize the specific properties of graphene-metal contacts with particular attention to the nature of metals, impact of fabrication process, Fermi level pinning, interface modifications induced through surface processes, charge transport mechanism, and edge contact formation.

  5. Resistive effects on line-tied magnetohydrodynamic modes in cylindrical geometry

    International Nuclear Information System (INIS)

    Delzanno, Gian Luca; Evstatiev, E. G.; Finn, John M.

    2007-01-01

    An investigation of the effect of resistivity on the linear stability of line-tied magnetohydrodynamic (MHD) modes is presented in cylindrical geometry, based on the method recently developed in the paper by Evstatiev et al. [Phys. Plasmas 13, 072902 (2006)]. The method uses an expansion of the full solution of the problem in one-dimensional radial eigenfunctions. This method is applied to study sausage modes (m=0, m being the poloidal wavenumber), kink modes (m=1), and m=2 modes. All these modes can be resistively unstable. It is found that m≠0 modes can be unstable below the ideal MHD threshold due to resistive diffusion of the field lines, with growth rates proportional to resistivity. For these resistive modes, there is no indication of tearing, i.e., current sheets or boundary layers due to ideal MHD singularities. That is, resistivity acts globally on the whole plasma column and not in layers. Modes with m=0, on the other hand, can exist as tearing modes if the equilibrium axial magnetic field reverses sign within the plasma

  6. EFFECTS OF EXTRACTIVES AND DENSITY ON NATURAL RESISTANCE OF WOODS TO TERMITE Nasutitermes corniger

    Directory of Open Access Journals (Sweden)

    Juarez Benigno Paes

    2015-12-01

    Full Text Available The evaluation of the natural resistance of wood to wood-destroying organisms is of fundamental importance in the choice of species to be used in buildings and furniture industry. Thus, the effects of extractives and wood density on biological resistance of Acacia mangium, Casuarina equisetifolia, Corymbia torelliana, Eucalyptus cloeziana, Tectona grandis and Caesalpinia echinata woods to the xylophagous termite Nasutitermes corniger was evaluated under laboratory conditions. Test samples, with dimensions of 2.00 x 2.54 x 0.64 cm (radial x tangential x longitudinal in four positions in pith-bark direction (internal heart, intermediate heart, outer heart and sapwood were taken. The woods were exposed to termite action for 28 days in no-choice feeding test. The samples not selected for the termite test were turned into sawdust and the extractive contents were obtained using the shavings that passed through the sieve of 40 and were retained in the sieve of 60 mesh. The wood natural resistance, within the pith-bark positions, for the studied species, is not correlated with the density and extractive content. However, among the woods, those with higher density and extractive content are more resistant. The woods with greater biological resistance to the termite Nasutitermes corniger (smaller mass loss, waste and survival time of insects are Corymbia torelliana and Caesalpinia echinata and of less resistance is Casuarina equisetifolia.

  7. Effect of vibration during fatiguing resistance exercise on subsequent muscle activity during maximal voluntary isometric contractions.

    Science.gov (United States)

    McBride, Jeffrey M; Porcari, John P; Scheunke, Mark D

    2004-11-01

    This investigation was designed to determine if vibration during fatiguing resistance exercise would alter associated patterns of muscle activity. A cross-over design was employed with 8 subjects completing a resistance exercise bout once with a vibrating dumbbell (V) (44 Hz, 3 mm displacement) and once without vibration (NV). For both exercise bouts, 10 sets were performed with a load that induced concentric muscle failure during the 10th repetition. The appropriate load for each set was determined during a pretest. Each testing session was separated by 1 week. Electromyography (EMG) was obtained from the biceps brachii muscle at 12 different time points during a maximum voluntary contraction (MVC) at a 170 degrees elbow angle after each set of the dumbbell exercise. The time points were as follows: pre (5 minutes before the resistance exercise bout), T1-T10 (immediately following each set of resistance exercise), and post (15 minutes after the resistance exercise bout). EMG was analyzed for median power frequency (MPF) and maximum (mEMG). NV resulted in a significant decrease in MPF at T1-T4 (p recruitment of high threshold motor units during fatiguing contractions. This may indicate the usage of vibration with resistance exercise as an effective tool for strength training athletes.

  8. Metrics for border management systems.

    Energy Technology Data Exchange (ETDEWEB)

    Duggan, Ruth Ann

    2009-07-01

    There are as many unique and disparate manifestations of border systems as there are borders to protect. Border Security is a highly complex system analysis problem with global, regional, national, sector, and border element dimensions for land, water, and air domains. The complexity increases with the multiple, and sometimes conflicting, missions for regulating the flow of people and goods across borders, while securing them for national security. These systems include frontier border surveillance, immigration management and customs functions that must operate in a variety of weather, terrain, operational conditions, cultural constraints, and geopolitical contexts. As part of a Laboratory Directed Research and Development Project 08-684 (Year 1), the team developed a reference framework to decompose this complex system into international/regional, national, and border elements levels covering customs, immigration, and border policing functions. This generalized architecture is relevant to both domestic and international borders. As part of year two of this project (09-1204), the team determined relevant relative measures to better understand border management performance. This paper describes those relative metrics and how they can be used to improve border management systems.

  9. Effects of Disclosing Sponsored Content in Blogs: How the Use of Resistance Strategies Mediates Effects on Persuasion

    NARCIS (Netherlands)

    E.A. van Reijmersdal (Eva); M.L. Fransen (Marieke); G. van Noort (Guda); S.J. Opree (Suzanna); L. Vandeberg (Lisa); Reusch, S. (Sanne); van Lieshout, F. (Floor); Boerman, S.C. (Sophie C.)

    2016-01-01

    textabstractThis article presents two studies examining the effects of disclosing online native advertising (i.e., sponsored content in blogs) on people’s brand attitude and purchase intentions. To investigate the mechanisms underlying these effects, we integrated resistance theories with the

  10. Effects of disclosing sponsored content in blogs : how the use of resistance strategies mediates effects on persuasion

    NARCIS (Netherlands)

    van Reijmersdal, E.A.; Fransen, M.L.; van Noort, G.; Opree, S.J.; Vandeberg, L.; Reusch, S.; van Lieshout, F.; Boerman, S.C.

    2016-01-01

    This article presents two studies examining the effects of disclosing online native advertising (i.e., sponsored content in blogs) on people’s brand attitude and purchase intentions. To investigate the mechanisms underlying these effects, we integrated resistance theories with the persuasion

  11. The metrics of science and technology

    CERN Document Server

    Geisler, Eliezer

    2000-01-01

    Dr. Geisler's far-reaching, unique book provides an encyclopedic compilation of the key metrics to measure and evaluate the impact of science and technology on academia, industry, and government. Focusing on such items as economic measures, patents, peer review, and other criteria, and supported by an extensive review of the literature, Dr. Geisler gives a thorough analysis of the strengths and weaknesses inherent in metric design, and in the use of the specific metrics he cites. His book has already received prepublication attention, and will prove especially valuable for academics in technology management, engineering, and science policy; industrial R&D executives and policymakers; government science and technology policymakers; and scientists and managers in government research and technology institutions. Geisler maintains that the application of metrics to evaluate science and technology at all levels illustrates the variety of tools we currently possess. Each metric has its own unique strengths and...

  12. Smart Grid Status and Metrics Report Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Balducci, Patrick J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Antonopoulos, Chrissi A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Clements, Samuel L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gorrissen, Willy J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kirkham, Harold [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Ruiz, Kathleen A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, David L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Weimar, Mark R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gardner, Chris [APQC, Houston, TX (United States); Varney, Jeff [APQC, Houston, TX (United States)

    2014-07-01

    A smart grid uses digital power control and communication technology to improve the reliability, security, flexibility, and efficiency of the electric system, from large generation through the delivery systems to electricity consumers and a growing number of distributed generation and storage resources. To convey progress made in achieving the vision of a smart grid, this report uses a set of six characteristics derived from the National Energy Technology Laboratory Modern Grid Strategy. The Smart Grid Status and Metrics Report defines and examines 21 metrics that collectively provide insight into the grid’s capacity to embody these characteristics. This appendix presents papers covering each of the 21 metrics identified in Section 2.1 of the Smart Grid Status and Metrics Report. These metric papers were prepared in advance of the main body of the report and collectively form its informational backbone.

  13. Metrics for Polyphonic Sound Event Detection

    Directory of Open Access Journals (Sweden)

    Annamaria Mesaros

    2016-05-01

    Full Text Available This paper presents and discusses various metrics proposed for evaluation of polyphonic sound event detection systems used in realistic situations where there are typically multiple sound sources active simultaneously. The system output in this case contains overlapping events, marked as multiple sounds detected as being active at the same time. The polyphonic system output requires a suitable procedure for evaluation against a reference. Metrics from neighboring fields such as speech recognition and speaker diarization can be used, but they need to be partially redefined to deal with the overlapping events. We present a review of the most common metrics in the field and the way they are adapted and interpreted in the polyphonic case. We discuss segment-based and event-based definitions of each metric and explain the consequences of instance-based and class-based averaging using a case study. In parallel, we provide a toolbox containing implementations of presented metrics.

  14. Polypropylene and polycarbonate radiosterilization: effects on the stress resistance

    International Nuclear Information System (INIS)

    Musico Filho, W.; Terence, M.C.; Guedes, S.M.L.; Araujo, E.S. de

    1994-01-01

    The gamma radiation effect on polymer sterilization used in the fabrication of medical supplies, national polycarbonate and polypropylene, was studied in function of the tensile strength. During the polycarbonate irradiation occur the scission of polymer chain and the crosslinking/scission of the polypropylene, but in the sterilization dose, 25 kGy, does not occur expressive changes in the tensile strength. After the polypropylene sterilization the tensile strength continues increasing as consequence of the crosslinking. Since the sixth day the oxidation reaction predominates as consequence of the radical migration to the amorphous region. (author). 7 refs, 6 figs

  15. Scale effect in fatigue resistance under complex stressed state

    International Nuclear Information System (INIS)

    Sosnovskij, L.A.

    1979-01-01

    On the basis the of the fatigue failure statistic theory obtained is the formula for calculated estimation of probabillity of failure under complex stressed state according to partial probabilities of failure under linear stressed state with provision for the scale effect. Also the formula for calculation of equivalent stress is obtained. The verification of both formulae using literary experimental data for plane stressed state torsion has shown that the error of estimations does not exceed 10% for materials with the ultimate strength changing from 61 to 124 kg/mm 2

  16. Effect of season on peripheral resistance to localised cold stress

    Science.gov (United States)

    Tanaka, M.; Harimura, Y.; Tochihara, Y.; Yamazaki, S.; Ohnaka, T.; Matsui, J.; Yoshida, K.

    1984-03-01

    This study was carried out to determine the effect that seasonal changes have on the effect of localised cold stress on peripheral temperatures using the foot immersion method with a cold water bath. The subjects were six males and four females. The data were obtained in April, July, October and January. Skin temperature of the right index finger, the forehead, the arm, the cheek, the second toe and the instep were measured before, during and after the immersion of the feet in water at 15°C for 10 mins, as well as oxygen consumption before immersion of the feet. The average finger temperature was highest during foot immersion in the summer, next highest in the winter, then spring, and the lowest during foot immersion in the autumn. The finger temperatures during the pre-immersion period in the autumn tended to be lower than in other seasons. The finger temperatures during the pre-immersion period affected the temperature change of the finger during the immersion period. The rate of increase of the toe temperature and the foot temperature during post-immersion in the summer and the spring were greater than those in the autumn and winter. Oxygen consumption during the pre-immersion period in the autumn was significantly lower than in the other seasons (pCooling the feet caused no significant changes in the temperatures the cheek, forehead or forearm. The cheek temperature in the summer and autumn was cooler than corresponding temperatures taken in the winter and spring.

  17. Effects of heat input on the pitting resistance of Inconel 625 welds by overlay welding

    Science.gov (United States)

    Kim, Jun Seok; Park, Young IL; Lee, Hae Woo

    2015-03-01

    The objective of this study was to establish the relationship between the dilution ratio of the weld zone and pitting resistance depending on the heat input to welding of the Inconel alloy. Each specimen was produced by electroslag welding using Inconel 625 as the filler metal. In the weld zone of each specimen, dendrite grains were observed near the fusion line and equiaxed grains were observed on the surface. It was also observed that a melted zone with a high Fe content was formed around the fusion line, which became wider as the welding heat input increased. In order to evaluate the pitting resistance, potentiodynamic polarization tests and CPT tests were conducted. The results of these tests confirmed that there is no difference between the pitting resistances of each specimen, as the structures of the surfaces were identical despite the effect of the differences in the welding heat input for each specimen and the minor dilution effect on the surface.

  18. An Innovative Metric to Evaluate Satellite Precipitation's Spatial Distribution

    Science.gov (United States)

    Liu, H.; Chu, W.; Gao, X.; Sorooshian, S.

    2011-12-01

    Thanks to its capability to cover the mountains, where ground measurement instruments cannot reach, satellites provide a good means of estimating precipitation over mountainous regions. In regions with complex terrains, accurate information on high-resolution spatial distribution of precipitation is critical for many important issues, such as flood/landslide warning, reservoir operation, water system planning, etc. Therefore, in order to be useful in many practical applications, satellite precipitation products should possess high quality in characterizing spatial distribution. However, most existing validation metrics, which are based on point/grid comparison using simple statistics, cannot effectively measure satellite's skill of capturing the spatial patterns of precipitation fields. This deficiency results from the fact that point/grid-wised comparison does not take into account of the spatial coherence of precipitation fields. Furth more, another weakness of many metrics is that they can barely provide information on why satellite products perform well or poor. Motivated by our recent findings of the consistent spatial patterns of the precipitation field over the western U.S., we developed a new metric utilizing EOF analysis and Shannon entropy. The metric can be derived through two steps: 1) capture the dominant spatial patterns of precipitation fields from both satellite products and reference data through EOF analysis, and 2) compute the similarities between the corresponding dominant patterns using mutual information measurement defined with Shannon entropy. Instead of individual point/grid, the new metric treat the entire precipitation field simultaneously, naturally taking advantage of spatial dependence. Since the dominant spatial patterns are shaped by physical processes, the new metric can shed light on why satellite product can or cannot capture the spatial patterns. For demonstration, a experiment was carried out to evaluate a satellite

  19. Effects of chlortetracycline and copper supplementation on antimicrobial resistance of fecal Escherichia coli from weaned pigs.

    Science.gov (United States)

    Agga, G E; Scott, H M; Amachawadi, R G; Nagaraja, T G; Vinasco, J; Bai, J; Norby, B; Renter, D G; Dritz, S S; Nelssen, J L; Tokach, M D

    2014-06-01

    Feed-grade chlortetracycline (CTC) and copper are both widely utilized in U.S. pig production. Cluster randomized experiment was conducted to evaluate the effects of CTC and copper supplementation in weaned pigs on antimicrobial resistance (AMR) among fecal Escherichia coli. Four treatment groups: control, copper, CTC, or copper plus CTC were randomly allocated to 32 pens with five pigs per pen. Fecal samples were collected weekly from three pigs per pen for six weeks. Two E. coli isolates per fecal sample were tested for phenotypic and genotypic resistance against antibiotics and copper. Data were analyzed with multilevel mixed effects logistic regression, multivariate probit analysis and discrete time survival analysis. CTC-supplementation was significantly (99% [95% CI=98-100%]) associated with increased tetracycline resistance compared to the control group (95% [95% CI=94-97%]). Copper supplementation was associated with decreased resistance to most of the antibiotics tested, including cephalosporins, over the treatment period. Overall, 91% of the E. coli isolates were multidrug resistant (MDR) (resistant to ≥3 antimicrobial classes). tetA and blaCMY-2 genes were positively associated (PpcoD were negatively associated with MDR. tetA and blaCMY-2 were positively associated with each other and in turn, these were negatively associated with both tetB and pcoD genes; which were also positively associated with one another. Copper minimum inhibitory concentration was not affected by copper supplementation or by pcoD gene carriage. CTC supplementation was significantly associated with increased susceptibilities of E. coli to copper (HR=7 [95% CI=2.5-19.5]) during treatment period. In conclusion, E. coli isolates from the nursery pigs exhibited high levels of antibiotic resistance, with diverse multi-resistant phenotypic profiles. The roles of copper supplementation in pig production, and pco-mediated copper resistance among E. coli in particular, need to be further

  20. MRP- and BCL-2-mediated drug resistance in human SCLC: effects of apoptotic sphingolipids in vitro.

    Science.gov (United States)

    Khodadadian, M; Leroux, M E; Auzenne, E; Ghosh, S C; Farquhar, D; Evans, R; Spohn, W; Zou, Y; Klostergaard, J

    2009-10-01

    Multidrug-resistance-associated protein (MRP) and BCL-2 contribute to drug resistance expressed in SCLC. To establish whether MRP-mediated drug resistance affects sphingolipid (SL)-induced apoptosis in SCLC, we first examined the human SCLC cell line, UMCC-1, and its MRP over-expressing, drug-resistant subline, UMCC-1/VP. Despite significantly decreased sensitivity to doxorubicin (Dox) and to the etoposide, VP-16, the drug-selected line was essentially equally as sensitive to treatment with exogenous ceramide (Cer), sphingosine (Sp) or dimethyl-sphingosine (DMSP) as the parental line. Next, we observed that high BCL-2-expressing human H69 SCLC cells, that were approximately 160-fold more sensitive to Dox than their combined BCL-2 and MRP-over-expressing (H69AR) counterparts, were only approximately 5-fold more resistant to DMSP. Time-lapse fluorescence microscopy of either UMCC cell line treated with DMSP-Coumarin revealed comparable extents and kinetics of SL uptake, further ruling out MRP-mediated effects on drug uptake. DMSP potentiated the cytotoxic activity of VP-16 and Taxol, but not Dox, in drug-resistant UMCC-1/VP cells. However, this sensitization did not appear to involve DMSP-mediated effects on the function of MRP in drug export; nor did DMSP strongly shift the balance of pro-apoptotic Sps and anti-apoptotic Sp-1-Ps in these cells. We conclude that SL-induced apoptosis markedly overcomes or bypasses MRP-mediated drug resistance relevant to SCLC and may suggest a novel therapeutic approach to chemotherapy for these tumors.

  1. Postactivation Potentation Effects From Accommodating Resistance Combined With Heavy Back Squats on Short Sprint Performance.

    Science.gov (United States)

    Wyland, Timothy P; Van Dorin, Joshua D; Reyes, G Francis Cisco

    2015-11-01

    Applying accommodating resistance combined with isoinertial resistance has been demonstrated to be effective in improving neuromuscular attributes important for sport performance. The main purpose of this study was to determine whether short sprints can be acutely enhanced after several sets of back squats with or without accommodating resistance. Twenty recreationally resistance-trained males (age: 23.3 ± 4.4 years; height: 178.9 ± 6.5 cm; weight: 88.3 ± 10.8 kg) performed pre-post testing on 9.1-m sprint time. Three different interventions were implemented in randomized order between pre-post 9.1-m sprints. On 3 separate days, subjects either sat for 5 minutes (CTRL), performed 5 sets of 3 repetitions at 85% of their 1 repetition maximum (1RM) with isoinertial load (STND), or performed 5 sets of 3 repetitions at 85% of their 1RM, with 30% of the total resistance coming from elastic band tension (BAND) between pre-post 9.1-m sprint testing. Posttesting for 9.1-m sprint time occurred immediately after the last set of squats (Post-Immediate) and on every minute for 4 minutes after the last set of squats (Post-1min, Post-2min, Post-3min, and Post-4min). Repeated-measures analysis of variance statistical analyses revealed no significant changes in sprint time across posttesting times during the CTRL and STND condition. During the BAND condition, sprint time significantly decreased from Post-Immediate to Post-4min (p = 0.002). The uniqueness of accommodating resistance could create an optimal postactivation potentiation effect to increase neuromuscular performance. Coaches and athletes can implement heavy accommodating resistance exercises to their warm-up when improving acute sprint time is desired.

  2. Effect of creatine supplementation and drop-set resistance training in untrained aging adults.

    Science.gov (United States)

    Johannsmeyer, Sarah; Candow, Darren G; Brahms, C Markus; Michel, Deborah; Zello, Gordon A

    2016-10-01

    To investigate the effects of creatine supplementation and drop-set resistance training in untrained aging adults. Participants were randomized to one of two groups: Creatine (CR: n=14, 7 females, 7 males; 58.0±3.0yrs, 0.1g/kg/day of creatine+0.1g/kg/day of maltodextrin) or Placebo (PLA: n=17, 7 females, 10 males; age: 57.6±5.0yrs, 0.2g/kg/day of maltodextrin) during 12weeks of drop-set resistance training (3days/week; 2 sets of leg press, chest press, hack squat and lat pull-down exercises performed to muscle fatigue at 80% baseline 1-repetition maximum [1-RM] immediately followed by repetitions to muscle fatigue at 30% baseline 1-RM). Prior to and following training and supplementation, assessments were made for body composition, muscle strength, muscle endurance, tasks of functionality, muscle protein catabolism and diet. Drop-set resistance training improved muscle mass, muscle strength, muscle endurance and tasks of functionality (pcreatine to drop-set resistance training significantly increased body mass (p=0.002) and muscle mass (p=0.007) compared to placebo. Males on creatine increased muscle strength (lat pull-down only) to a greater extent than females on creatine (p=0.005). Creatine enabled males to resistance train at a greater capacity over time compared to males on placebo (p=0.049) and females on creatine (p=0.012). Males on creatine (p=0.019) and females on placebo (p=0.014) decreased 3-MH compared to females on creatine. The addition of creatine to drop-set resistance training augments the gains in muscle mass from resistance training alone. Creatine is more effective in untrained aging males compared to untrained aging females. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Complex long-distance effects of mutations that confer linezolid resistance in the large ribosomal subunit

    Science.gov (United States)

    Fulle, Simone; Saini, Jagmohan S.; Homeyer, Nadine; Gohlke, Holger

    2015-01-01

    The emergence of multidrug-resistant pathogens will make current antibiotics ineffective. For linezolid, a member of the novel oxazolidinone class of antibiotics, 10 nucleotide mutations in the ribosome have been described conferring resistance. Hypotheses for how these mutations affect antibiotics binding have been derived based on comparative crystallographic studies. However, a detailed description at the atomistic level of how remote mutations exert long-distance effects has remained elusive. Here, we show that the G2032A-C2499A double mutation, located > 10 Å away from the antibiotic, confers linezolid resistance by a complex set of effects that percolate to the binding site. By molecular dynamics simulations and free energy calculations, we identify U2504 and C2452 as spearheads among binding site nucleotides that exert the most immediate effect on linezolid binding. Structural reorganizations within the ribosomal subunit due to the mutations are likely associated with mutually compensating changes in the effective energy. Furthermore, we suggest two main routes of information transfer from the mutation sites to U2504 and C2452. Between these, we observe cross-talk, which suggests that synergistic effects observed for the two mutations arise in an indirect manner. These results should be relevant for the development of oxazolidinone derivatives that are active against linezolid-resistant strains. PMID:26202966

  4. Effects of Hall current and electrical resistivity on the stability of gravitating anisotropic quantum plasma

    Science.gov (United States)

    Bhakta, S.; Prajapati, R. P.

    2018-02-01

    The effects of Hall current and finite electrical resistivity are studied on the stability of uniformly rotating and self-gravitating anisotropic quantum plasma. The generalized Ohm's law modified by Hall current and electrical resistivity is used along with the quantum magnetohydrodynamic fluid equations. The general dispersion relation is derived using normal mode analysis and discussed in the parallel and perpendicular propagations. In the parallel propagation, the Jeans instability criterion, expression of critical Jeans wavenumber, and Jeans length are found to be independent of non-ideal effects and uniform rotation but in perpendicular propagation only rotation affects the Jeans instability criterion. The unstable gravitating mode modified by Bohm potential and the stable Alfven mode modified by non-ideal effects are obtained separately. The criterion of firehose instability remains unaffected due to the presence of non-ideal effects. In the perpendicular propagation, finite electrical resistivity and quantum pressure anisotropy modify the dispersion relation, whereas no effect of Hall current was observed in the dispersion characteristics. The Hall current, finite electrical resistivity, rotation, and quantum corrections stabilize the growth rate. The stability of the dynamical system is analyzed using the Routh-Hurwitz criterion.

  5. Environmental Maternal Effects Mediate the Resistance of Maritime Pine to Biotic Stress

    Science.gov (United States)

    Vivas, María; Zas, Rafael; Sampedro, Luis; Solla, Alejandro

    2013-01-01

    The resistance to abiotic stress is increasingly recognised as being impacted by maternal effects, given that environmental conditions experienced by parent (mother) trees affect stress tolerance in offspring. We hypothesised that abiotic environmental maternal effects may also mediate the resistance of trees to biotic stress. The influence of maternal environment and maternal genotype and the interaction of these two factors on early resistance of Pinus pinaster half-sibs to the Fusarium circinatum pathogen was studied using 10 mother genotypes clonally replicated in two contrasting environments. Necrosis length of infected seedlings was 16% shorter in seedlings grown from favourable maternal environment seeds than in seedlings grown from unfavourable maternal environment seeds. Damage caused by F. circinatum was mediated by maternal environment and maternal genotype, but not by seed mass. Mechanisms unrelated to seed provisioning, perhaps of epigenetic nature, were probably involved in the transgenerational plasticity of P. pinaster, mediating its resistance to biotic stress. Our findings suggest that the transgenerational resistance of pines due to an abiotic stress may interact with the defensive response of pines to a biotic stress. PMID:23922944

  6. Environmental maternal effects mediate the resistance of maritime pine to biotic stress.

    Directory of Open Access Journals (Sweden)

    María Vivas

    Full Text Available The resistance to abiotic stress is increasingly recognised as being impacted by maternal effects, given that environmental conditions experienced by parent (mother trees affect stress tolerance in offspring. We hypothesised that abiotic environmental maternal effects may also mediate the resistance of trees to biotic stress. The influence of maternal environment and maternal genotype and the interaction of these two factors on early resistance of Pinus pinaster half-sibs to the Fusarium circinatum pathogen was studied using 10 mother genotypes clonally replicated in two contrasting environments. Necrosis length of infected seedlings was 16% shorter in seedlings grown from favourable maternal environment seeds than in seedlings grown from unfavourable maternal environment seeds. Damage caused by F. circinatum was mediated by maternal environment and maternal genotype, but not by seed mass. Mechanisms unrelated to seed provisioning, perhaps of epigenetic nature, were probably involved in the transgenerational plasticity of P. pinaster, mediating its resistance to biotic stress. Our findings suggest that the transgenerational resistance of pines due to an abiotic stress may interact with the defensive response of pines to a biotic stress.

  7. Effect of composition on corrosion resistance of high-alloy austenitic stainless steel weld metals

    International Nuclear Information System (INIS)

    Marshall, P.I.; Gooch, T.G.

    1993-01-01

    The corrosion resistance of stainless steel weld metal in the ranges of 17 to 28% chromium (Cr), 6 to 60% nickel (Ni), 0 to 9% molybdenum (Mo), and 0.0 to 0.37% nitrogen (N) was examined. Critical pitting temperatures were determined in ferric chloride (FeCl 3 ). Passive film breakdown potentials were assessed from potentiodynamic scans in 3% sodium chloride (NaCl) at 50 C. Potentiodynamic and potentiostatic tests were carried out in 30% sulfuric acid (H 2 SO 4 ) ar 25 C, which was representative of chloride-free acid media of low redox potential. Metallographic examination and microanalysis were conducted on the test welds. Because of segregation of alloying elements, weld metal pitting resistance always was lower than that of matching composition base steel. The difference increased with higher Cr, Mo, and N contents. Segregation also reduced resistance to general corrosion in H 2 SO 4 , but the effect relative to the base steel was less marked than with chloride pitting. Segregation of Cr, Mo, and N in fully austenitic deposits decreased as the Ni' eq- Cr' eq ratio increased. Over the compositional range studied, weld metal pitting resistance was dependent mainly on Mo content and segregation. N had less effect than in wrought alloys. Both Mo and N enhanced weld metal corrosion resistance in H 2 SO 4

  8. Effect of non-uniform surface resistance on the quality factor of superconducting niobium cavity

    Science.gov (United States)

    Tan, Weiwei; Lu, Xiangyang; Yang, Ziqin; Zhao, Jifei; Yang, Deyu; Yang, Yujia

    2016-08-01

    The formula Rs = G /Q0 is commonly used in the calculation of the surface resistance of radio frequency niobium superconducting cavities. The applying of such equation is under the assumption that surface resistance is consistent over the cavity. However, the distribution of the magnetic field varies over the cavity. The magnetic field in the equator is much higher than that in the iris. According to Thermal Feedback Theory, it leads non-uniform distribution of the density of heat flux, which results in a different temperature distribution along the cavity inter surface. The BCS surface resistance, which depends largely on the temperature, is different in each local inner surface. In this paper, the effect of surface non-uniform resistance on the quality factor has been studied, through the calculation of Q0 in the original definition of it. The results show that it is necessary to consider the non-uniform distribution of magnetic field when the accelerating field is above 20 MV/m for TESLA cavities. Also, the effect of inhomogeneity of residual resistance on the quality factor is discussed. Its distribution barely affects the quality factor.

  9. The effects of argon ion bombardment on the corrosion resistance of tantalum

    Science.gov (United States)

    Ramezani, A. H.; Sari, A. H.; Shokouhy, A.

    2017-02-01

    Application of ion beam has been widely used as a surface modification method to improve surface properties. This paper investigates the effect of argon ion implantation on surface structure as well as resistance against tantalum corrosion. In this experiment, argon ions with energy of 30 keV and in doses of 1 × 1017-10 × 1017 ions/cm2 were used. The surface bombardment with inert gases mainly produces modified topography and morphology of the surface. Atomic Force Microscopy was also used to patterned the roughness variations prior to and after the implantation phase. Additionally, the corrosion investigation apparatus wear was applied to compare resistance against tantalum corrosion both before and after ion implantation. The results show that argon ion implantation has a substantial impact on increasing resistance against tantalum corrosion. After the corrosion test, scanning electron microscopy (SEM) analyzed the samples' surface morphologies. In addition, the elemental composition is characterized by energy-dispersive X-ray (EDX) analysis. The purpose of this paper was to obtain the perfect condition for the formation of tantalum corrosion resistance. In order to evaluate the effect of the ion implantation on the corrosion behavior, potentiodynamic tests were performed. The results show that the corrosion resistance of the samples strongly depends on the implantation doses.

  10. Symmetric Kullback-Leibler Metric Based Tracking Behaviors for Bioinspired Robotic Eyes.

    Science.gov (United States)

    Liu, Hengli; Luo, Jun; Wu, Peng; Xie, Shaorong; Li, Hengyu

    2015-01-01

    A symmetric Kullback-Leibler metric based tracking system, capable of tracking moving targets, is presented for a bionic spherical parallel mechanism to minimize a tracking error function to simulate smooth pursuit of human eyes. More specifically, we propose a real-time moving target tracking algorithm which utilizes spatial histograms taking into account symmetric Kullback-Leibler metric. In the proposed algorithm, the key spatial histograms are extracted and taken into particle filtering framework. Once the target is identified, an image-based control scheme is implemented to drive bionic spherical parallel mechanism such that the identified target is to be tracked at the center of the captured images. Meanwhile, the robot motion information is fed forward to develop an adaptive smooth tracking controller inspired by the Vestibuloocular Reflex mechanism. The proposed tracking system is designed to make the robot track dynamic objects when the robot travels through transmittable terrains, especially bumpy environment. To perform bumpy-resist capability under the condition of violent attitude variation when the robot works in the bumpy environment mentioned, experimental results demonstrate the effectiveness and robustness of our bioinspired tracking system using bionic spherical parallel mechanism inspired by head-eye coordination.

  11. Symmetric Kullback-Leibler Metric Based Tracking Behaviors for Bioinspired Robotic Eyes

    Directory of Open Access Journals (Sweden)

    Hengli Liu

    2015-01-01

    Full Text Available A symmetric Kullback-Leibler metric based tracking system, capable of tracking moving targets, is presented for a bionic spherical parallel mechanism to minimize a tracking error function to simulate smooth pursuit of human eyes. More specifically, we propose a real-time moving target tracking algorithm which utilizes spatial histograms taking into account symmetric Kullback-Leibler metric. In the proposed algorithm, the key spatial histograms are extracted and taken into particle filtering framework. Once the target is identified, an image-based control scheme is implemented to drive bionic spherical parallel mechanism such that the identified target is to be tracked at the center of the captured images. Meanwhile, the robot motion information is fed forward to develop an adaptive smooth tracking controller inspired by the Vestibuloocular Reflex mechanism. The proposed tracking system is designed to make the robot track dynamic objects when the robot travels through transmittable terrains, especially bumpy environment. To perform bumpy-resist capability under the condition of violent attitude variation when the robot works in the bumpy environment mentioned, experimental results demonstrate the effectiveness and robustness of our bioinspired tracking system using bionic spherical parallel mechanism inspired by head-eye coordination.

  12. Global Phenotypic Characterization of Effects of Fluoroquinolone Resistance Selection on the Metabolic Activities and Drug Susceptibilities of Clostridium perfringens Strains

    Directory of Open Access Journals (Sweden)

    Miseon Park

    2014-01-01

    Full Text Available Fluoroquinolone resistance affects toxin production of Clostridium perfringens strains differently. To investigate the effect of fluoroquinolone resistance selection on global changes in metabolic activities and drug susceptibilities, four C. perfringens strains and their norfloxacin-, ciprofloxacin-, and gatifloxacin-resistant mutants were compared in nearly 2000 assays, using phenotype microarray plates. Variations among mutant strains resulting from resistance selection were observed in all aspects of metabolism. Carbon utilization, pH range, osmotic tolerance, and chemical sensitivity of resistant strains were affected differently in the resistant mutants depending on both the bacterial genotype and the fluoroquinolone to which the bacterium was resistant. The susceptibilities to gentamicin and erythromycin of all resistant mutants except one increased, but some resistant strains were less susceptible to amoxicillin, cefoxitin, ceftriaxone, chloramphenicol, and metronidazole than their wild types. Sensitivity to ethidium bromide decreased in some resistant mutants and increased in others. Microarray analysis of two gatifloxacin-resistant mutants showed changes in metabolic activities that were correlated with altered expression of various genes. Both the chemical structures of fluoroquinolones and the genomic makeup of the wild types influenced the changes found in resistant mutants, which may explain some inconsistent reports of the effects of therapeutic use of fluoroquinolones on clinical isolates of bacteria.

  13. Heavy irradiation effects in radiation-resistant optical fibers

    Energy Technology Data Exchange (ETDEWEB)

    Shikama, Tatsuo [Tohoku Univ., Oarai, Ibaraki (Japan). Oarai Branch, Inst. for Materials Research

    1998-07-01

    Development of a system for optical measurements in a nuclear reactor has been progressing to investigate dynamic changes in a material caused by heavy irradiation. In such system, transfer of optical signals to out-pile measuring systems is being attempted by the use of optical fibers. In this report, the characteristics of optical fibers in the heavy irradiation field were summarized. It has been known that amorphous silica might produce radiolysis and structural defects by the exposure to ionizing radiation. The effects of heavy irradiation on molten silica were extremely complicated. A large intensity of visible light absorption occurred from an early time during start-up of the reactor. The absorption range was limited below 700 nm for the radiation associating fast neutron and the absorption was mostly attributed to non-bridging oxygen hole center. The depletion of optical transferring capacity under the radiation might be related to the internal stress. Therefore, it seems desirable to use optical fibers in the conditions without leading too much stress. (M.N.)

  14. Effects of response preference on resistance to change.

    Science.gov (United States)

    Ringdahl, Joel E; Berg, Wendy K; Wacker, David P; Crook, Kayla; Molony, Maggie A; Vargo, Kristina K; Neurnberger, Jodi E; Zabala, Karla; Taylor, Christopher J

    2018-01-01

    Treatments based on differential reinforcement of alternative behavior, such as functional communication training, are widely used. Research regarding the maintenance of related treatment effects is limited. Nevin and Wacker (2013) provided a conceptual framework, rooted in behavioral momentum theory, for the study of treatment maintenance that addressed two components: (a) reemergence of problem behavior, and (b) continued expression of appropriate behavior. In the few studies on this topic, focus has been on variables impacting the reemergence of problem behavior, with fewer studies evaluating the persistence of appropriate behavior. Given the findings from applied research related to functional communication training, variables related to response topography, such as response preference, may impact this aspect of maintenance. In the current study, the impact of response preference on persistence was evaluated in the context of functional communication training for individuals who did not exhibit problem behavior (Experiment 1) and for individuals with a history of reinforcement for problem behavior (Experiment 2). High-preferred mands were more persistent than low-preferred mands. These findings suggest that response related variables, such as response preference, impact response persistence and further suggest that response related variables should be considered when developing interventions such as functional communication training. © 2018 Society for the Experimental Analysis of Behavior.

  15. Developing a Metric for the Cost of Green House Gas Abatement

    Science.gov (United States)

    2017-02-28

    The authors introduce the levelized cost of carbon (LCC), a metric that can be used to evaluate MassDOT CO2 abatement projects in terms of their cost-effectiveness. The study presents ways in which the metric can be used to rank projects. The data ar...

  16. 75 FR 51272 - Proposed Collection; Comment Request; STAR METRICS-Science and Technology in America's...

    Science.gov (United States)

    2010-08-19

    ... on Innovation, Competitiveness and Science SUMMARY: In compliance with the requirement of Section... Technology for America's Reinvestment: Measuring the Effects of Research on Innovation, Competitiveness and... aim of STAR METRICS is twofold. The initial goal of STAR METRICS is to provide mechanisms that will...

  17. Effects of a Commercial Chitosan Formulation on Bark Beetle (Coleoptera: Curculionidae) Resistance Parameters in Loblolly Pine

    Science.gov (United States)

    K. D. Klepzig; B. L. Strom

    2011-01-01

    A commercially available chitosan product, Beyond™, was evaluated for its effects on loblolly pine, Pinus taeda L., responses believed related to bark beetle resistance. Treatments were applied 4 times at approx. 6-wk intervals between May and November 2008. Five treatments were evaluated: ground application (soil drench), foliar application, ground...

  18. Effects of fish oil on oxidation resistance of VLDL in hypertriglyceridemic patients

    NARCIS (Netherlands)

    Hau, M.-F.; Smelt, A.H.M.; Bindels, A.J.G.H.; Sijbrands, E.J.G.; Laarse, A. van der; Onkenhout, W.; Duyvenvoorde, W. van; Princen, H.M.G.

    1996-01-01

    In hypertriglyceridemic (HTG) patients the addition of fish oil to the diet causes a marked reduction in the concentration of triglyceride-rich lipoproteins in the serum. To investigate the effects of fish oil on the oxidation resistance of VLDL and LDL in HTG patients, nine male patients received 1

  19. Effect of magnesium aluminum silicate glass on the thermal shock resistance of BN matrix composite ceramics

    NARCIS (Netherlands)

    Cai, Delong; Jia, Dechang; Yang, Zhihua; Zhu, Qishuai; Ocelik, Vaclav; Vainchtein, Ilia D.; De Hosson, Jeff Th M.; Zhou, Yu

    The effects of magnesium aluminum silicate (MAS) glass on the thermal shock resistance and the oxidation behavior of h-BN matrix composites were systematically investigated at temperature differences from 600 degrees C up to 1400 degrees C. The retained strength rate of the composites rose with the

  20. Debris filtering effectiveness and pressure drop tests of debris resistance-bottom end piece

    International Nuclear Information System (INIS)

    Chung, Moon Ki; Song, Chul Hwa; Chung, Heung June; Won, Soon Yeun; Cho, Young Ro; Kim, Bok Deuk

    1992-03-01

    In this final report, described are the test conditions and test procedures for the debris filtering effectiveness and pressure drop tests for developing the Debris Resistance-Bottom End Piece (DR-BEP). And the test results are tabulated for later evaluation. (Author)

  1. Effects of β-Glucans and resistant starch on fermentation of recalcitrant fibers in growing pigs

    NARCIS (Netherlands)

    Vries, de S.; Gerrits, W.J.J.; Kabel, M.A.; Zijlstra, Ruurd; Vasanthan, Thava

    2017-01-01

    Effects of the presence of β-glucans and resistant starch in diets on nutrient and fiber degradability of rapeseed meal [RSM] (Brassica napus) and Distillers Dried Grain with Solubles (DDGS) were tested in a 2 × 3 factorial arrangement. Two basal diets, containing either 500 g/kg RSM or DDGS and

  2. Flow resistance interactions on hillslopes with heterogeneous attributes: Effects on runoff hydrograph characteristics

    Science.gov (United States)

    An improved modeling framework for capturing the effects of dynamic resistance to overland flow is developed for intensively managed landscapes. The framework builds on the WEPP model but it removes the limitations of the “equivalent” plane and static roughness assumption. The enhanced model therefo...

  3. Effects of bed-load movement on flow resistance over bed forms

    Indian Academy of Sciences (India)

    Abstract. The effect of bed-load transport on flow resistance of alluvial channels with undulated bed was experimentally investigated. The experiments were carried out in a tilting flume 250mm wide and 12·5m long with glass-sides of rectan- gular cross-section and artificial dune shaped floor that was made from Plexi-glass.

  4. Effect of annealing treatments on normal state resistivity of YBa 2 ...

    African Journals Online (AJOL)

    Samples of YBa2(Cu1-xTix)3Oy superconductor with x=0.00 , 0.01, 0.03 have been prepared by solide state reaction method. The effect of annealing treatments on normal electrical resistivity has been done using the bipolaron model. The results of this study show the increase of localized charge when the dopant content ...

  5. Effectiveness of small daily amounts of progressive resistance training for frequent neck/shoulder pain

    DEFF Research Database (Denmark)

    Andersen, Lars; Saervoll, Charlotte A; Mortensen, Ole S

    2011-01-01

    Regular physical exercise is a cornerstone in rehabilitation programs, but adherence to comprehensive exercise remains low. This study determined the effectiveness of small daily amounts of progressive resistance training for relieving neck/shoulder pain in healthy adults with frequent symptoms...

  6. Effect of iron on pancreatic beta cell function and insulin resistance ...

    African Journals Online (AJOL)

    Background: Increase in total body iron store has been reported in the aetiology and development of diabetes mellitus. The effect of iron supplementation in female with respect to the incidence of diabetes mellitus was investigated on the pancreatic beta cell function and insulin resistance in normal female rats. Methods: ...

  7. Approaches to studying environmental effects on resistance of Pinus taeda L. to Dendroctonus frontalis Zimmermann

    Science.gov (United States)

    Peter L. Lorio

    1996-01-01

    There are a number of ways to approach the problem of assessing the effects of environmental conditions, such as water regime, on tree physiological responses and resistance to bark beetle attack.It helps to keep in mind that environmental factors operate throught physiological processes (Fig. 1, and Kramer 1986), and that there are concepts, such as plant growth-...

  8. Probiotics cultures in animal feed: Effects on ruminal fermentation, immune responses, and resistance to infectious diseases

    Science.gov (United States)

    We evaluated the effects of probiotics included in dairy cattle and mice feed on ruminal fermentation, immune responses, and resistance to Johne’s disease. To unveil the underlying mechanisms, dairy cattle were either fed Bovamine (1.04 x 10**9 cfu of Lactobacillus acidophilus NP51 plus 2.04 x 10**...

  9. Effects of processing method and moisture history on laboratory fungal resistance of wood-HDPE composites.

    Science.gov (United States)

    Craig M. Clemons; Rebecca E. Ibach

    2004-01-01

    The purpose of this study was to clarify the effects of composite processing and moisture sorption on laboratory fungal resistance of wood-plastic composites. A 2-week water soaking or cyclic boiling-drying procedure was used to infuse moisture into composites made from high-density polyethylene filled with 50 percent wood flour and processed by extrusion, compression...

  10. Explaining the Effects of Narrative in an Entertainment Television Program: Overcoming Resistance to Persuasion

    Science.gov (United States)

    Moyer-Guse, Emily; Nabi, Robin L.

    2010-01-01

    Research has examined the ability of entertainment-education (E-E) programs to influence behavior across a variety of health and social issues. However, less is known about the underlying mechanisms that account for these effects. In keeping with the extended elaboration likelihood model (E-ELM) and the entertainment overcoming resistance model…

  11. Contribution of current carrier mobility variation to piezo-resistive effect in SmS

    International Nuclear Information System (INIS)

    Vasil'ev, L.N.; Kaminskij, V.V.

    1999-01-01

    The value of the contribution from the change in the current carriers mobility and pressure to the piezo-resistive effect value in the materials on the basis of the samarium, monosulfide is studied. The conclusion, that the value of the piezoresistance of comprehensive compression should not exceed 7x10 -3 MPa -1 at T=300 K, experimental data [ru

  12. The Effects of Constant versus Varied Reinforcers on Preference and Resistance to Change

    Science.gov (United States)

    Milo, Jessie-Sue; Mace, F. Charles; Nevin, John A.

    2010-01-01

    Previous research has demonstrated that factors such as reinforcer frequency, amount, and delay have similar effects on resistance to change and preference. In the present study, 4 boys with autism made choices between a constant reinforcer (one that was the same food item every trial) and a varied food reinforcer (one that varied randomly between…

  13. Effect of high-intensity interval and resistance training on cardiovascular risk factors in MS patients

    OpenAIRE

    Severijns, Tobias; Wijckmans, Ferdy

    2017-01-01

    In this paper, the effect of high-intensity interval plus resistance training (HIITR) on cardiovascular risk factors was studied through a quasi-experimental study. Outcome measures are: endurance capacity, body composition, physical activity level, isometric muscle strength, oral glucose tolerance, blood lipids and lipoprotein - cholesterol.

  14. Fracture resistance of direct inlay-retained adhesive bridges : Effect of pontic material and occlusal morphology

    NARCIS (Netherlands)

    Breuklander, Marijn; Salihoglu-Yener, Esra; Ozcan, Mutlu

    This study evaluated the effect of a) pontic materials and b) occlusal morphologies on the fracture resistance of fiber-reinforced composite (FRC) inlay-retained fixed dental prostheses (FDP). Inlay-retained FRC FPDs (N=45, n=9) were constructed using a) resin composite (deep anatomy), b) natural

  15. Host-plant-mediated effects of Nadefensin on herbivore and pathogen resistance in Nicotiana attenuata

    Directory of Open Access Journals (Sweden)

    Baldwin Ian T

    2008-10-01

    Full Text Available Abstract Background The adage from Shakespeare, "troubles, not as single spies, but in battalions come," holds true for Nicotiana attenuata, which is commonly attacked by both pathogens (Pseudomonas spp. and herbivores (Manduca sexta in its native habitats. Defense responses targeted against the pathogens can directly or indirectly influence the responses against the herbivores. Nadefensin is an effective induced defense gene against the bacterial pathogen Pseudomonas syringae pv tomato (PST DC3000, which is also elicited by attack from M. sexta larvae, but whether this defense protein influences M. sexta's growth and whether M. sexta-induced Nadefensin directly or indirectly influences PST DC3000 resistance are unknown. Results M. sexta larvae consumed less on WT and on Nadefensin-silenced N. attenuata plants that had previously been infected with PST DC3000 than on uninfected plants. WT plants infected with PST DC3000 showed enhanced resistance to PST DC3000 and decreased leaf consumption by M. sexta larvae, but larval mass gain was unaffected. PST DC3000-infected Nadefensin-silenced plants were less resistant to subsequent PST DC3000 challenge, and on these plants, M. sexta larvae consumed less and gained less mass. WT and Nadefensin-silenced plants previously damaged by M. sexta larvae were better able to resist subsequent PST DC3000 challenges than were undamaged plants. Conclusion These results demonstrate that Na-defensin directly mediates defense against PST DC3000 and indirectly against M. sexta in N. attenuata. In plants that were previously infected with PST DC3000, the altered leaf chemistry in PST DC3000-resistant WT plants and PST DC3000-susceptible Nadefensin-silenced plants differentially reduced M. sexta's leaf consumption and mass gain. In plants that were previously damaged by M. sexta, the combined effect of the altered host plant chemistry and a broad spectrum of anti-herbivore induced metabolomic responses was more

  16. Pyridostigmine Improves the Effects of Resistance Exercise Training after Myocardial Infarction in Rats

    Science.gov (United States)

    Feriani, Daniele J.; Coelho-Júnior, Hélio J.; de Oliveira, Juliana C. M. F.; Delbin, Maria A.; Mostarda, Cristiano T.; Dourado, Paulo M. M.; Caperuto, Érico C.; Irigoyen, Maria C. C.; Rodrigues, Bruno

    2018-01-01

    Myocardial infarction (MI) remains the leading cause of morbidity and mortality worldwide. Exercise training and pharmacological treatments are important strategies to minimize the deleterious effects of MI. However, little is known about the effects of resistance training combined with pyridostigmine bromide (PYR) treatment on cardiac and autonomic function, as well as on the inflammatory profile after MI. Thus, in the present study, male Wistar rats were randomly assigned into: control (Cont); sedentary infarcted (Inf); PYR – treated sedentary infarcted rats (Inf+P); infarcted rats undergoing resistance exercise training (Inf+RT); and infarcted rats undergoing PYR treatment plus resistance training (Inf+RT+P). After 12 weeks of resistance training (15–20 climbs per session, with a 1-min rest between each climb, at a low to moderate intensity, 5 days a week) and/or PYR treatment (0.14 mg/mL of drink water), hemodynamic function, autonomic modulation, and cytokine expressions were evaluated. We observed that 3 months of PYR treatment, either alone or in combination with exercise, can improve the deleterious effects of MI on left ventricle dimensions and function, baroreflex sensitivity, and autonomic parameters, as well as systemic and tissue inflammatory profile. Furthermore, additional benefits in a maximal load test and anti-inflammatory state of skeletal muscle were found when resistance training was combined with PYR treatment. Thus, our findings suggest that the combination of resistance training and PYR may be a good therapeutic strategy since they promote additional benefits on skeletal muscle anti-inflammatory profile after MI. PMID:29483876

  17. Effect of Tetracycline Dose and Treatment Mode on Selection of Resistant Coliform Bacteria in Nursery Pigs.

    Science.gov (United States)

    Græsbøll, Kaare; Damborg, Peter; Mellerup, Anders; Herrero-Fresno, Ana; Larsen, Inge; Holm, Anders; Nielsen, Jens Peter; Christiansen, Lasse Engbo; Angen, Øystein; Ahmed, Shahana; Folkesson, Anders; Olsen, John Elmerdahl

    2017-06-15

    This study describes the results of a randomized clinical trial investigating the effect of oxytetracycline treatment dose and mode of administration on the selection of antibiotic-resistant coliform bacteria in fecal samples from nursery pigs. Nursery pigs (pigs of 4 to 7 weeks of age) in five pig herds were treated with oxytetracycline for Lawsonia intracellularis -induced diarrhea. Each group was randomly allocated to one of five treatment groups: oral flock treatment with a (i) high (20 mg/kg of body weight), (ii) medium (10 mg/kg), or (iii) low (5 mg/kg) dose, (iv) oral pen-wise (small-group) treatment (10 mg/kg), and (v) individual intramuscular injection treatment (10 mg/kg). All groups were treated once a day for 5 days. In all groups, treatment caused a rise in the numbers and proportions of tetracycline-resistant coliform bacteria right after treatment, followed by a significant drop by the time that the pigs left the nursery unit. The counts and proportions of tetracycline-resistant coliforms did not vary significantly between treatment groups, except immediately after treatment, when the highest treatment dose resulted in the highest number of resistant coliforms. A control group treated with tiamulin did not show significant changes in the numbers or proportions of tetracycline-resistant coliforms. Selection for tetracycline-resistant coliforms was significantly correlated to selection for ampicillin- and sulfonamide-resistant strains but not to selection for cefotaxime-resistant strains. In conclusion, the difference in the dose of oxytetracycline and the way in which the drug was applied did not cause significantly different levels of selection of tetracycline-resistant coliform bacteria under the conditions tested. IMPORTANCE Antimicrobial resistance is a global threat to human health. Treatment of livestock with antimicrobials has a direct impact on this problem, and there is a need to improve the ways that we use antimicrobials in livestock

  18. Effect of Tetracycline Dose and Treatment Mode on Selection of Resistant Coliform Bacteria in Nursery Pigs

    Science.gov (United States)

    Græsbøll, Kaare; Damborg, Peter; Mellerup, Anders; Herrero-Fresno, Ana; Larsen, Inge; Holm, Anders; Nielsen, Jens Peter; Christiansen, Lasse Engbo; Angen, Øystein; Ahmed, Shahana

    2017-01-01

    ABSTRACT This study describes the results of a randomized clinical trial investigating the effect of oxytetracycline treatment dose and mode of administration on the selection of antibiotic-resistant coliform bacteria in fecal samples from nursery pigs. Nursery pigs (pigs of 4 to 7 weeks of age) in five pig herds were treated with oxytetracycline for Lawsonia intracellularis-induced diarrhea. Each group was randomly allocated to one of five treatment groups: oral flock treatment with a (i) high (20 mg/kg of body weight), (ii) medium (10 mg/kg), or (iii) low (5 mg/kg) dose, (iv) oral pen-wise (small-group) treatment (10 mg/kg), and (v) individual intramuscular injection treatment (10 mg/kg). All groups were treated once a day for 5 days. In all groups, treatment caused a rise in the numbers and proportions of tetracycline-resistant coliform bacteria right after treatment, followed by a significant drop by the time that the pigs left the nursery unit. The counts and proportions of tetracycline-resistant coliforms did not vary significantly between treatment groups, except immediately after treatment, when the highest treatment dose resulted in the highest number of resistant coliforms. A control group treated with tiamulin did not show significant changes in the numbers or proportions of tetracycline-resistant coliforms. Selection for tetracycline-resistant coliforms was significantly correlated to selection for ampicillin- and sulfonamide-resistant strains but not to selection for cefotaxime-resistant strains. In conclusion, the difference in the dose of oxytetracycline and the way in which the drug was applied did not cause significantly different levels of selection of tetracycline-resistant coliform bacteria under the conditions tested. IMPORTANCE Antimicrobial resistance is a global threat to human health. Treatment of livestock with antimicrobials has a direct impact on this problem, and there is a need to improve the ways that we use antimicrobials in

  19. Robustness Metrics: Consolidating the multiple approaches to quantify Robustness

    DEFF Research Database (Denmark)

    Göhler, Simon Moritz; Eifler, Tobias; Howard, Thomas J.

    2016-01-01

    robustness metrics; 3) Functional expectancy and dispersion robustness metrics; and 4) Probability of conformance robustness metrics. The goal was to give a comprehensive overview of robustness metrics and guidance to scholars and practitioners to understand the different types of robustness metrics...

  20. Partial rectangular metric spaces and fixed point theorems.

    Science.gov (United States)

    Shukla, Satish

    2014-01-01

    The purpose of this paper is to introduce the concept of partial rectangular metric spaces as a generalization of rectangular metric and partial metric spaces. Some properties of partial rectangular metric spaces and some fixed point results for quasitype contraction in partial rectangular metric spaces are proved. Some examples are given to illustrate the observed results.

  1. Measuring Information Security: Guidelines to Build Metrics

    Science.gov (United States)

    von Faber, Eberhard

    Measuring information security is a genuine interest of security managers. With metrics they can develop their security organization's visibility and standing within the enterprise or public authority as a whole. Organizations using information technology need to use security metrics. Despite the clear demands and advantages, security metrics are often poorly developed or ineffective parameters are collected and analysed. This paper describes best practices for the development of security metrics. First attention is drawn to motivation showing both requirements and benefits. The main body of this paper lists things which need to be observed (characteristic of metrics), things which can be measured (how measurements can be conducted) and steps for the development and implementation of metrics (procedures and planning). Analysis and communication is also key when using security metrics. Examples are also given in order to develop a better understanding. The author wants to resume, continue and develop the discussion about a topic which is or increasingly will be a critical factor of success for any security managers in larger organizations.

  2. Energy functionals for Calabi-Yau metrics

    International Nuclear Information System (INIS)

    Headrick, M; Nassar, A

    2013-01-01

    We identify a set of ''energy'' functionals on the space of metrics in a given Kähler class on a Calabi-Yau manifold, which are bounded below and minimized uniquely on the Ricci-flat metric in that class. Using these functionals, we recast the problem of numerically solving the Einstein equation as an optimization problem. We apply this strategy, using the ''algebraic'' metrics (metrics for which the Kähler potential is given in terms of a polynomial in the projective coordinates), to the Fermat quartic and to a one-parameter family of quintics that includes the Fermat and conifold quintics. We show that this method yields approximations to the Ricci-flat metric that are exponentially accurate in the degree of the polynomial (except at the conifold point, where the convergence is polynomial), and therefore orders of magnitude more accurate than the balanced metrics, previously studied as approximations to the Ricci-flat metric. The method is relatively fast and easy to implement. On the theoretical side, we also show that the functionals can be used to give a heuristic proof of Yau's theorem

  3. Effects of Synchronous Rolling on Microstructure, Hardness, and Wear Resistance of Laser Multilayer Cladding

    Science.gov (United States)

    Zhao, W.; Zha, G. C.; Xi, M. Z.; Gao, S. Y.

    2018-03-01

    A synchronous rolling method was proposed to assist laser multilayer cladding, and the effects of this method on microstructure, microhardness, and wear resistance were studied. Results show that the microstructure and mechanical properties of the traditional cladding layer exhibit periodic inhomogeneity. Synchronous rolling breaks the columnar dendrite crystals to improve the uniformity of the organization, and the residual plastic energy promotes the precipitation of strengthening phases, as CrB, M7C3, etc. The hardness and wear resistance of the extruded cladding layer increase significantly because of the grain refinement, formation of dislocations, and dispersion strengthening. These positive significances of synchronous rolling provide a new direction for laser cladding technology.

  4. The effect of ion implantation on the resistance of 316L stainless steel to crevice corrosion

    International Nuclear Information System (INIS)

    Bombara, G.; Cavallini, M.

    1983-01-01

    The results of an investigation of the influence of aluminium, titanium and scandium implantation on the electrochemical and chemical crevice corrosion behaviour of 316L stainless steel are presented and discussed. Ion implantation, in addition to improving markedly the protective quality of the passive film at the free corrosion potential, greatly increases the resistance of 316L stainless steel to crevice corrosion in both neutral NaCl and acidic FeCl 3 solutions. A moderate decrease in pitting resistance is possibly due to coverage effect of implanted species on the surface molybdenum constituent. (Auth.)

  5. Effect of tetracycline dose and treatment mode on selection of resistant coliform bacteria in nursery pigs

    DEFF Research Database (Denmark)

    Græsbøll, Kaare; Damborg, Peter; Mellerup, Anders

    2017-01-01

    This study describes the results of a randomized clinical trial investigating the effect of oxytetracycline treatment dose and mode of administration on the selection of antibiotic-resistant coliform bacteria in fecal samples from nursery pigs. Nursery pigs (pigs of 4 to 7 weeks of age) in five pig...... by the time that the pigs left the nursery unit. The counts and proportions of tetracyclineresistant coliforms did not vary significantly between treatment groups, except immediately after treatment, when the highest treatment dose resulted in the highest number of resistant coliforms. A control group treated...

  6. Effect of temperature on the crack resistance of a molybdenum alloy with 30% tungsten

    International Nuclear Information System (INIS)

    Uskov, E.I.; Babak, A.V.; D'yachkov, A.P.; Platonov, V.A.

    1986-01-01

    Results are presented for a study of the effect of temperature on the crack resistance of molybdenum alloy with 30% tungsten (Mo - 30% W), and data are presented for the crack resistance of commercial-purity molybdenum and tungsten obtained by power metallurgy in the temperature range 20-1800 C. It was found that the nature of failure for Mo-30% W alloy depends on test temperature; in the temperature range 20 C-T /SUP d/ /SUB br/ (upper boundary for the temperature range of the ductile to brittle transition), failure is unstable in nature, and at temperatures exceeding this transition, it occurs by steady main crack development

  7. Effects of Copper and Sulfur Additions on Corrosion Resistance and Machinability of Austenitic Stainless Steel

    International Nuclear Information System (INIS)

    Kim, Soon Tae; Park, Yong Soo; Kim, Hyung Joon

    1999-01-01

    Effects of Cu and S on corrosion resistance and machinability of austenitic stainless steel were investigated using immersion test, metallographic examination, Auger surface analysis and tool life test with single point turning tools. Corrosion resistance of the experimental Cu containing alloys in 18.4N H 2 SO 4 at 80 ∼ 120 .deg. C and 3N HCl at 40 .deg. C decreased as S content increased. However, one of the experimental alloys (Fe- 18%Cr- 21%Ni-3.2%Mo- 1.6%W- 0.2%N- 3.1%Cu- 0.091%S) showed general and pitting corrosion resistance equivalent to that of CW12MW in highly concentrated SO 4 2- environment. The alloy also showed pitting corrosion resistance superior to super stainless steel such as 654SMO in Cl - environment. The reasons why the increase in S content deteriorated the corrosion resistance were first, that the number and size of (Mn, Cr)S sulfides having corrosion resistance lower than that of matrix increased, leading to pitting corrosion and second, that rapid dissolution of the matrix around the pits was caused by adsorbed S. However, the alloy containing 3.1 %Cu and 0.091 % S maintained high general and pitting corrosion resistance due to heavily enriched noble Cu through selective dissolution of active Fe and Ni. The tool life for 3.1 % Cu + 0.091 % S added alloy was about four times that of 0.06%Cu + 0.005% S added alloy due to high shear strain rate generated by Cu addition giving easy cross slip of dislocation, lubrication of ductile (Mn, Cr)S sulfides adhering to tool crater surface and low cutting force resulting from thin continuous sulfides formed in chips during machining

  8. Effect of resistance training regimens on treadmill running and neuromuscular performance in recreational endurance runners.

    Science.gov (United States)

    Mikkola, Jussi; Vesterinen, Ville; Taipale, Ritva; Capostagno, Benoit; Häkkinen, Keijo; Nummela, Ari

    2011-10-01

    The purpose of this study was to assess the effects of heavy resistance, explosive resistance, and muscle endurance training on neuromuscular, endurance, and high-intensity running performance in recreational endurance runners. Twenty-seven male runners were divided into one of three groups: heavy resistance, explosive resistance or muscle endurance training. After 6 weeks of preparatory training, the groups underwent an 8-week resistance training programme as a supplement to endurance training. Before and after the 8-week training period, maximal strength (one-repetition maximum), electromyographic activity of the leg extensors, countermovement jump height, maximal speed in the maximal anaerobic running test, maximal endurance performance, maximal oxygen uptake ([V·]O(₂max)), and running economy were assessed. Maximal strength improved in the heavy (P = 0.034, effect size ES = 0.38) and explosive resistance training groups (P = 0.003, ES = 0.67) with increases in leg muscle activation (heavy: P = 0.032, ES = 0.38; explosive: P = 0.002, ES = 0.77). Only the heavy resistance training group improved maximal running speed in the maximal anaerobic running test (P = 0.012, ES = 0.52) and jump height (P = 0.006, ES = 0.59). Maximal endurance running performance was improved in all groups (heavy: P = 0.005, ES = 0.56; explosive: P = 0.034, ES = 0.39; muscle endurance: P = 0.001, ES = 0.94), with small though not statistically significant improvements in [V·]O(₂max) (heavy: ES = 0.08; explosive: ES = 0.29; muscle endurance: ES = 0.65) and running economy (ES in all groups running endurance performance. However, both heavy and explosive strength training were beneficial in improving neuromuscular characteristics, and heavy resistance training in particular contributed to improvements in high-intensity running characteristics. Thus, endurance runners should include heavy resistance training in their training programmes to enhance endurance performance, such as

  9. Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis

    Directory of Open Access Journals (Sweden)

    Liping Wang

    2009-12-01

    Full Text Available The postantibiotic effects (PAEs and postantibiotic sub-MIC effects (PA SMEs of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05 regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

  10. Postantibiotic effects and postantibiotic sub-MIC effects of tilmicosin, erythromycin and tiamulin on erythromycin-resistant Streptococcus suis.

    Science.gov (United States)

    Wang, Liping; Zhang, Yuanshu

    2009-10-01

    The postantibiotic effects (PAEs) and postantibiotic sub-MIC effects (PA SMEs) of tilmicosin, erythromycin and tiamulin on erythromycin-susceptible and erythromycin-resistant strains of Streptococcus suis (M phenotype) were investigated in vitro. Tilmicosin and tiamulin induced significantly longer PAE and PA SME against both erythromycin-susceptible and erythromycin-resistant strains than did erythromycin. The durations of PAE and PA SMEs were proportional to the concentrations of drugs used for exposure. The PA SMEs were substantially longer than PAEs on S. suis (P<0.05) regardless of the antimicrobial used for exposure. The results indicated that the PAE and PA SME could help in the design of efficient control strategies for infection especially caused by erythromycin-resistant S. suis and that they may provide additional valuable information for the rational drug use in clinical practice.

  11. Effects of slag-based silicon fertilizer on rice growth and brown-spot resistance.

    Science.gov (United States)

    Ning, Dongfeng; Song, Alin; Fan, Fenliang; Li, Zhaojun; Liang, Yongchao

    2014-01-01

    It is well documented that slag-based silicon fertilizers have beneficial effects on the growth and disease resistance of rice. However, their effects vary greatly with sources of slag and are closely related to availability of silicon (Si) in these materials. To date, few researches have been done to compare the differences in plant performance and disease resistance between different slag-based silicon fertilizers applied at the same rate of plant-available Si. In the present study both steel and iron slags were chosen to investigate their effects on rice growth and disease resistance under greenhouse conditions. Both scanning electron microscopy (SEM) and transmission electron microscopy (TEM) were used to examine the effects of slags on ultrastructural changes in leaves of rice naturally infected by Bipolaris oryaze, the causal agent of brown spot. The results showed that both slag-based Si fertilizers tested significantly increased rice growth and yield, but decreased brown spot incidence, with steel slag showing a stronger effect than iron slag. The results of SEM analysis showed that application of slags led to more pronounced cell silicification in rice leaves, more silica cells, and more pronounced and larger papilla as well. The results of TEM analysis showed that mesophyll cells of slag-untreated rice leaf were disorganized, with colonization of the fungus (Bipolaris oryzae), including chloroplast degradation and cell wall alterations. The application of slag maintained mesophyll cells relatively intact and increased the thickness of silicon layer. It can be concluded that applying slag-based fertilizer to Si-deficient paddy soil is necessary for improving both rice productivity and brown spot resistance. The immobile silicon deposited in host cell walls and papillae sites is the first physical barrier for fungal penetration, while the soluble Si in the cytoplasm enhances physiological or induced resistance to fungal colonization.

  12. Effect of a Home-Based Virtual Reality Intervention for Children with Cerebral Palsy Using Super Pop VR Evaluation Metrics: A Feasibility Study

    Directory of Open Access Journals (Sweden)

    Yuping Chen

    2015-01-01

    Full Text Available Objective. The purpose of this pilot study was to determine whether Super Pop VR, a low-cost virtual reality (VR system, was a feasible system for documenting improvement in children with cerebral palsy (CP and whether a home-based VR intervention was effective. Methods. Three children with CP participated in this study and received an 8-week VR intervention (30 minutes × 5 sessions/week using the commercial EyeToy Play VR system. Reaching kinematics measured by Super Pop VR and two fine motor tools (Bruininks-Oseretsky Test of Motor Proficiency second edition, BOT-2, and Pediatric Motor Activity Log, PMAL were tested before, mid, and after intervention. Results. All children successfully completed the evaluations using the Super Pop VR system at home where 85% of the reaches collected were used to compute reaching kinematics, which is compatible with literature using expensive motion analysis systems. Only the child with hemiplegic CP and more impaired arm function improved the reaching kinematics and functional use of the affected hand after intervention. Conclusion. Super Pop VR proved to be a feasible evaluation tool in children with CP.

  13. Reversible Resistance Switching Effect in Amorphous Ge1Sb4Te7 Thin Films without Phase Transformation

    International Nuclear Information System (INIS)

    Hua-Jun, Sun; Li-Song, Hou; Yi-Qun, Wu; Xiao-Dong, Tang

    2009-01-01

    We demonstrate a reversible resistance switching effect that does not rely on amorphous-crystalline phase transformation in a nanoscale capacitor-like cell using Ge 1 Sb 4 Te 7 films as the working material. The polarity and amplitude of the applied electric voltage switches the cell resistance between low- and high-resistance states, as revealed in the current-voltage characteristics of the film by conductive atomic force microscopy (CAFM). This reversible SET/RESET switching effect is induced by voltage pulses and their polarity. The change of electrical resistance due to the switching effect is approximately two orders of magnitude

  14. Postulation of rust resistance genes in Nordic spring wheat genotypes and identification of widely effective sources of resistance against the Australian rust flora.

    Science.gov (United States)

    Randhawa, Mandeep; Bansal, Urmil; Lillemo, Morten; Miah, Hanif; Bariana, Harbans

    2016-11-01

    Wild relatives, landraces and cultivars from different geographical regions have been demonstrated as the sources of genetic variation for resistance to rust diseases. This study involved assessment of diversity for resistance to three rust diseases among a set of Nordic spring wheat cultivars. These cultivars were tested at the seedling stage against several pathotypes of three rust pathogens in the greenhouse. All stage stem rust resistance genes Sr7b, Sr8a, Sr12, Sr15, Sr17, Sr23 and Sr30, and leaf rust resistance genes Lr1, Lr3a, Lr13, Lr14a, Lr16 and Lr20 were postulated either singly or in different combinations among these cultivars. A high proportion of cultivars were identified to carry linked rust resistance genes Sr15 and Lr20. Although 51 cultivars showed variation against Puccinia striiformis f. sp. tritici (Pst) pathotypes used in this study, results were not clearly contrasting to enable postulation of stripe rust resistance genes in these genotypes. Stripe rust resistance gene Yr27 was postulated in four cultivars and Yr1 was present in cultivar Zebra. Cultivar Tjalve produced low stripe rust response against all Pst pathotypes indicating the presence either of a widely effective resistance gene or combination of genes with compensating pathogenic specificities. Several cultivars carried moderate to high level of APR to leaf rust and stripe rust. Seedling stem rust susceptible cultivar Aston exhibited moderately resistant to moderately susceptible response, whereas other cultivars belonging to this class were rated moderately susceptible or higher. Molecular markers linked with APR genes Yr48, Lr34/Yr18/Sr57, Lr68 and Sr2 detected the presence of these genes in some genotypes.

  15. Effect of the interface resistance in non-local Hanle measurements

    International Nuclear Information System (INIS)

    Villamor, Estitxu; Hueso, Luis E.; Casanova, Fèlix

    2015-01-01

    We use lateral spin valves with varying interface resistance to measure non-local Hanle effect in order to extract the spin-diffusion length of the non-magnetic channel. A general expression that describes spin injection and transport, taking into account the influence of the interface resistance, is used to fit our results. Whereas the fitted spin-diffusion length value is in agreement with the one obtained from standard non-local measurements in the case of a finite interface resistance, in the case of transparent contacts a clear disagreement is observed. The use of a corrected expression, recently proposed to account for the anisotropy of the spin absorption at the ferromagnetic electrodes, still yields a deviation of the fitted spin-diffusion length which increases for shorter channel distances. This deviation shows how sensitive the non-local Hanle fittings are, evidencing the complexity of obtaining spin transport information from such type of measurements

  16. Boron effect on fabrication properties and service behaviour of complex corrosion-resistant steels

    International Nuclear Information System (INIS)

    Gol'dshtejn, Ya.E.; Piskunova, A.I.; Shmatko, M.N.

    1978-01-01

    In order to determine the optimum boron admixtures for the improvement of the technological plasticity without the considerable reduction in the corrosion resistance of the complex alloy Cr-Ni-Mo steels, industrial heats of the 03KH16N15M3, 03KH17N14M3 and other steels, containing 0.0005-0.003% boron, have been researched. The plasticity, corrosion resistance and microstructure of certain steels have been determined. It is shown that small additions of boron enhance the technological plasticity during the ingot rolling. In order to prevent a sharp reduction in the corrosion resistance, the boron content should be confined to 0.0015% and the quenching temperature raised to 1,120-1,150 deg C. The positive effect of the quenching temperature increase is accounted for by the solution of the excess phases and by the reduction of the dislocation density in the near-the-boundary zones

  17. Investigation of surface resistance of copper in classical and anomalous skin-effect region

    International Nuclear Information System (INIS)

    Kutovoj, V.A.; Egorov, A.M.

    2008-01-01

    The surface resistance of copper in classical and anomalous skin-effect region has been investigated, and the surface resistance improvement factor equal to the ratio of the surface resistance of copper at room temperature to that of helium temperature, depending on the electromagnetic field frequency, has been determined. The improvement factor has been shown to have inverse power law dependence on frequency. The frequencies at which the improvement factor of copper equals 10 have been determined. It has been found that the quality factor of a resonance high-frequency system made of copper, operating at temperature T ≥ 4.2 K can be increased 10 times or more as against a quality factor of a resonance high-frequency system operating at room temperature

  18. Influence of glutamine on the effect of resistance exercise on cardiac ANP in rats

    Directory of Open Access Journals (Sweden)

    Romeu Rodrigues de Souza

    2015-03-01

    Full Text Available Various nutritional supplements (herbs, vitamins, and micronutrients improve responses and adaptations to resistance exercise. ANP is a heart hormone that contributes to fluid, electrolyte and blood pressure homeostasis through its natriuretic and vasodilative actions. In the present study, the adaptation of ANP in response to resistance exercise was investigated in rats supplemented with glutamine for five weeks. The results showed that supplementation with glutamine did not influence the number of ANP granules per atrial cardiocyte in sedentary animals. In exercised-trained rats, the number and diameter of the granules was significantly higher in comparison with the control group and in exercised animals supplemented with glutamine there was significant increase in the number and diameter of ANP granules compared with controls. Altogether, these data indicated that in resistance exercise rats, glutamine significantly enhances cardiac ANP thus implicating the beneficial effects of glutamine supplementation to the ANP system.

  19. Antimicrobial use in swine production and its effect on the swine gut microbiota and antimicrobial resistance.

    Science.gov (United States)

    Holman, Devin B; Chénier, Martin R

    2015-11-01

    Antimicrobials have been used in swine production at subtherapeutic levels since the early 1950s to increase feed efficiency and promote growth. In North America, a number of antimicrobials are available for use in swine. However, the continuous administration of subtherapeutic, low concentrations of antimicrobials to pigs also provides selective pressure for antimicrobial-resistant bacteria and resistance determinants. For this reason, subtherapeutic antimicrobial use in livestock remains a source of controversy and concern. The swine gut microbiota demonstrates a number of changes in response to antimicrobial administration depending on the dosage, duration of treatment, age of the pigs, and gut location that is sampled. Both culture-independent and -dependent studies have also shown that the swine gut microbiota contains a large number of antimicrobial resistance determinants even in the absence of antimicrobial exposure. Heavy metals, such as zinc and copper, which are often added at relatively high doses to swine feed, may also play a role in maintaining antimicrobial resistance and in the stability of the swine gut microbiota. This review focuses on the use of antimicrobials in swine production, with an emphasis on the North American regulatory context, and their effect on the swine gut microbiota and on antimicrobial resistance determinants in the gut microbiota.

  20. The Effect of Resistance Training on Cardio-Metabolic Factors in Males with Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    Ghalavand

    2014-10-01

    Full Text Available Background Diabetes is one of the most important metabolic diseases in the world and exercise is a common advice to manage diabetes and reduce its complications. Objectives The aim of this study was to investigate the effect of resistance training on blood glucose, blood pressure and resting heart rate in males with type 2 diabetes. Materials and Methods In this semi-experimental study, 20 males with type 2 diabetes with mean age of 46 ± 3.4 years old who met the inclusion criteria were selected. The participants were randomly assigned into resistance training (n = 10 and control (n = 10 groups. Resistance exercise training program was performed for eight weeks, three sessions per week. Cardiovascular and biochemical parameters were measured before and after the intervention. To analyze the measured parameters changes t-test was used at P ≤ 0.05 significance level. Results After eight weeks, a significant decrease in fasting blood sugar (P = 0.002, glycosylated hemoglobin (P = 0.025 and systolic blood pressure (P = 0.022 was observed in the resistance group. In addition, there was a significant difference in blood sugar (P = 0.003 and glycosylated hemoglobin (P = 0.031 between the two groups. Conclusions Findings of this study confirmed the positive influence of resistance training to control blood glucose and blood pressure in males with type 2 diabetes.