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Sample records for efekta ot pyrvichna

  1. Superhump Period of MASTER OT

    Science.gov (United States)

    Garnavich, Peter; McClelland, Colin

    2013-02-01

    We observed the optical transient MASTER OT J065608.28+744455.2 (ATEL #4783) with the Vatican Advanced Technology Telescope (VATT) and VATT4K CCD camera. V-band imaging began at 2013 Feb. 5.15 (UT) and continued for 3.3 hours with a time resolution of 22 seconds.

  2. OT-Combiners Via Secure Computation

    DEFF Research Database (Denmark)

    Harnik, Danny; Ishai, Yuval; Kushilevitz, Eyal

    2008-01-01

    of faulty candidates (t = Ω(n)). Previous OT-combiners required either ω(n) or poly(k) calls to the n candidates, where k is a security parameter, and produced only a single secure OT. We demonstrate the usefulness of the latter result by presenting several applications that are of independent interest......An OT-combiner implements a secure oblivious transfer (OT) protocol using oracle access to n OT-candidates of which at most t may be faulty. We introduce a new general approach for combining OTs by making a simple and modular use of protocols for secure computation. Specifically, we obtain an OT......, strengthen the security, and improve the efficiency of previous OT-combiners. In particular, we obtain the first constant-rate OT-combiners in which the number of secure OTs being produced is a constant fraction of the total number of calls to the OT-candidates, while still tolerating a constant fraction...

  3. 75 FR 51169 - OTS Minority Depository Institutions Advisory Committee

    Science.gov (United States)

    2010-08-18

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision [Docket ID: OTS-2010-0026] OTS Minority... (OTS). ACTION: Notice. SUMMARY: The Charter for the OTS Minority Depository Institutions Advisory... of the Treasury to announce the renewal of the OTS Minority Depository Institutions Advisory...

  4. LATERAL SURVIVAL: AN OT ACCOUNT

    Directory of Open Access Journals (Sweden)

    Moira Yip

    2004-12-01

    Full Text Available When laterals are the targets of phonological processes, laterality may or may not survive. In a fixed feature geometry, [lateral] should be lost if its superordinate node is eliminated by either the spreading of a neighbouring node, or by coda neutralization. So if [lateral] is under Coronal (Blevins 1994, it should be lost under Place assimilation, and if [lateral] is under Sonorant Voicing (Rice & Avery 1991 it should be lost by rules that spread voicing. Yet in some languages lateral survives such spreading intact. Facts like these argue against a universal attachment of [lateral] under either Coronal or Sonorant Voicing, and in favour of an account in terms of markedness constraints on feature-co-occurrence (Padgett 2000. The core of an OT account is that IFIDENTLAT is ranked above whatever causes neutralization, such as SHARE-F or *CODAF. laterality will survive. If these rankings are reversed, we derive languages in which laterality is lost. The other significant factor is markedness. High-ranked feature co-occurrence constraints like *LATDORSAL can block spreading from affecting laterals at all.

  5. Fabrication of PEDOT-OTS-patterned ITO substrates

    NARCIS (Netherlands)

    Herzer, N.; Wienk, M.M.; Schmit, P.; Spoelstra, A.B.; Hendriks, C.E.; Oosterhout, S.D.; Höppener, S.; Schubert, U.S.

    2010-01-01

    The fabrication of a poly(3,4-ethylenedioxythiophene) (PEDOT) pattern is demonstrated. As template, an n-octadecyltrichlorosilane (OTS) monolayer self-assembled on indium tin oxide (ITO) was structured by UV–ozone photolithography, resulting in an ITO–OTS patterned surface. The conducting properties

  6. 12 CFR 510.5 - Release of unpublished OTS information.

    Science.gov (United States)

    2010-01-01

    ... ORGANIZATIONAL REGULATIONS § 510.5 Release of unpublished OTS information. (a) Scope. (1) This section applies to... their official capacities. Examples of unpublished information include: (i) Information in the memory of...

  7. Changeover Inference: Estimating the Relationship Between DT and OT Data

    National Research Council Canada - National Science Library

    Dippery, Kevin

    1997-01-01

    ... which has undergone developmental testing. Using a re-sampling method called the Bootstrap, the sampling variance and standard error of the changeover factor are calculated, as are confidence intervals for the OT failure rate of a new system...

  8. 12 CFR 500.10 - The OTS or The Office.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false The OTS or The Office. 500.10 Section 500.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY AGENCY ORGANIZATION AND FUNCTIONS General Organization § 500.10 The OTS or The Office. The Office of Thrift Supervision (referred to as “OTS” or “Office”) is an office of the...

  9. 12 CFR 502.50 - What fees does OTS charge?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What fees does OTS charge? 502.50 Section 502.50 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES... consolidated with a savings association on the Consolidated Statement of Condition of the Thrift Financial...

  10. Recent optical activity of the blazar OT 355

    Science.gov (United States)

    Bachev, R.; Kurtenkov, A.; Nikolov, Y.; Spassov, B.; Boeva, S.; Latev, G.; Dimitrova, R. V. Munoz

    2017-06-01

    The Flat Spectrum Radio Quasar OT 355 (also known as 7C 173240.70+385949.00, z=0.975) was typically observed to be in the optical between 16th and 21th magnitude (CRTS, http://nesssi.cacr.caltech.edu/catalina/20011332/113321380764100137p.html).

  11. 12 CFR 563b.115 - How will OTS review my business plan?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How will OTS review my business plan? 563b.115... business plan? (a) OTS will review your business plan to determine that it demonstrates a safe and sound... will be determinative. OTS will review every case on its merits. (b) You must file your business plan...

  12. A categorization of customer concerns for an OT front-end of innovation process in an IT/OT convergence context

    OpenAIRE

    Bonnetto , Emilie; YANNOU , Bernard; Bertoluci , Gwenola; Boly , Vincent; Alvarez , Jorge

    2016-01-01

    International audience; Operational Technologies (OT) are designed to monitor and control plants. OT are increasingly mixed with Information Technologies (IT) in global solutions. A conventional customer inquiry is no more sufficient to get enough data about Customer Concerns (CC). Indeed, an IT OT solution is the nervous system of a company; it intertwines people processes and functions. For specification step, one must now capture negative perceptions in the interrelationships with other ac...

  13. OT - Education for the health services of the future

    DEFF Research Database (Denmark)

    Hansen, Bodil Winther; Sørensen, Annette; Hove, Anne

    OT - Education for the health services of the future This presentation offers knowledge about which qualifications the health services and OT practice in general demand from Occupational Therapists. The study was developed in a wider context of the constant reflection within higher education...... as a result of the rapid pace of change in society. The Faculty of Occupational Therapy in Copenhagen wanted to enable the graduates in the best possible way to meet the employers’ demands as to qualifications. Furthermore, the aim was to develop and guarantee the quality of the educations offered...... by University College Oeresund. To express the level of education to be achieved in terms of competences and learning outcome, the study was inspired by the tuning process of educational structures in Europe, which is part of the Bologna process to integrate higher education area in Europe. The study is based...

  14. Optimization of OT-MACH Filter Generation for Target Recognition

    Science.gov (United States)

    Johnson, Oliver C.; Edens, Weston; Lu, Thomas T.; Chao, Tien-Hsin

    2009-01-01

    An automatic Optimum Trade-off Maximum Average Correlation Height (OT-MACH) filter generator for use in a gray-scale optical correlator (GOC) has been developed for improved target detection at JPL. While the OT-MACH filter has been shown to be an optimal filter for target detection, actually solving for the optimum is too computationally intensive for multiple targets. Instead, an adaptive step gradient descent method was tested to iteratively optimize the three OT-MACH parameters, alpha, beta, and gamma. The feedback for the gradient descent method was a composite of the performance measures, correlation peak height and peak to side lobe ratio. The automated method generated and tested multiple filters in order to approach the optimal filter quicker and more reliably than the current manual method. Initial usage and testing has shown preliminary success at finding an approximation of the optimal filter, in terms of alpha, beta, gamma values. This corresponded to a substantial improvement in detection performance where the true positive rate increased for the same average false positives per image.

  15. MASTER-SAAO: contradictory SN and flaring OT

    Science.gov (United States)

    Balanutsa, P.; Lipunov, V.; Buckley, D.; Gorbovskoy, E.; Tiurina, N.; Kuznetsov, A.; Kornilov, V.; Gress, O.; Pogrosheva, T.; Shumkov, V.; Vladimirov, V.; Vlasenko, D.; Kuvshinov, D.; Gabovich, A.

    2017-07-01

    MASTER-SAAO auto-detection system ( Lipunov et al., "MASTER Global Robotic Net", Advances in Astronomy, 2010, 30L ) discovered OT source at (RA, Dec) = 03h 42m 50.70s , -01d 52m 28s.7 on 2017-07-01.1753UT with unfiltered (6 images), that contradicts to Ia type detected in ATEL #10240 , ATEL #10225 for ATLAS17dcl ( http://www.supernova.thistlethwaites.com/sn2017/sndate.html ). It is in 8.4"W,20"S of PGC135685 with Btc=15.13, Vgsr=2773 http://leda.univ-lyon1.fr/ledacat.cgi?PGC135685 Spectral observations are required.

  16. Evaluation and selection of CASE tool for SMART OTS development

    International Nuclear Information System (INIS)

    Park, K. O; Seo, S. M.; Seo, Y. S.; Koo, I. S.; Jang, M. H.

    1999-01-01

    CASE(Computer-Aided Software Engineering) tool is a software that aids in software engineering activities such as requirement analysis, design, testing, configuration management, and project management. The evaluation and selection of commercial CASE tools for the specific software development project is not a easy work because the technical ability of an evaluator and the maturity of a software development organization are required. In this paper, we discuss selection strategies, characteristic survey, evaluation criteria, and the result of CASE tool selection for the development of SMART(System-integrated Modular Advanced ReacTor) OTS(Operator Training Simulator)

  17. 12 CFR 502.55 - Where can I find OTS's fee schedule?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Where can I find OTS's fee schedule? 502.55 Section 502.55 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND... fees in a Thrift Bulletin. OTS will publish these fees at least 30 days before they are effective. ...

  18. 12 CFR 502.60 - When will OTS adjust, add, waive, or eliminate a fee?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false When will OTS adjust, add, waive, or eliminate a fee? 502.60 Section 502.60 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Fees § 502.60 When will OTS adjust, add, waive, or eliminate a fee? Under...

  19. 12 CFR 516.10 - How does OTS compute time periods under this part?

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false How does OTS compute time periods under this part? 516.10 Section 516.10 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY APPLICATION PROCESSING PROCEDURES § 516.10 How does OTS compute time periods under this part? In computing...

  20. 12 CFR 516.170 - When will OTS conduct a meeting on an application?

    Science.gov (United States)

    2010-01-01

    ... application, or otherwise determines that a meeting will benefit the decision-making process. OTS may limit... inform the applicant and all commenters requesting a meeting of its decision to grant or deny a meeting request, or of its decision to conduct a meeting on its own initiative. (c) If OTS decides to conduct a...

  1. 12 CFR 563.146 - Will the OTS permit my capital distribution?

    Science.gov (United States)

    2010-01-01

    ... under 12 U.S.C. 1831o(d)(1)(B). (b) Your proposed capital distribution raises safety or soundness... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Will the OTS permit my capital distribution... SAVINGS ASSOCIATIONS-OPERATIONS Capital Distributions § 563.146 Will the OTS permit my capital...

  2. Consonant harmony in Nilotic: contrastive specifications and Stratal OT

    Directory of Open Access Journals (Sweden)

    Sara Mackenzie

    2016-07-01

    Full Text Available Through analyses of dental harmony in four Nilotic languages, this paper argues both for contrastive representations and for a stratal version of Optimality Theory. Dholuo, Päri, Shilluk and Anywa all have dental harmony patterns which bar the co-occurrence of dental and alveolar segments. Details of the dental harmony patterning vary between languages and are tied to contrasts in the inventory. In Anywa, harmony is non-structure-preserving and an allophonic dental nasal surfaces in harmonic forms. This pattern can be analyzed in a stratal model of OT but leads to a ranking paradox if only a single level of evaluation is used. Further support for a stratal analysis can be found in the interaction between harmony and consonant mutation processes in the four languages. In Dholuo, harmony applies at the stem level and consonant mutation results in disharmonic surface forms in morphologically complex words. In Anywa, harmony applies later, at the word level, and words formed through consonant mutation must obey the dental harmony restrictions.

  3. 78 FR 76768 - Removal of Transferred OTS Regulations Regarding Disclosure and Reporting of CRA-Related...

    Science.gov (United States)

    2013-12-19

    ... of competent jurisdiction, or by operation of law. \\1\\ Dodd-Frank Wall Street Reform and Consumer... the OTS was abolished by Title III of the Dodd-Frank Act. Part 390, subpart H is largely redundant of...

  4. Inflatable capsule recovery raft using OTS pontoons and other components, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of the proposed innovation is to research and study the feasibility of using pontoons (based on Off the Shelf (OTS) equipment) to make an inflatable...

  5. OT2_smalhotr_3: Herschel Extreme Lensing Line Observations (HELLO)

    Science.gov (United States)

    Malhotra, S.

    2011-09-01

    We request 59.8 hours of Herschel time to observe 20 normal star-forming galaxies in the [CII] 158 micron and [OI] 63 micron lines. These galaxies lie at high redshift (1OT1, 49 high redshift IR luminous galaxies were approved for spectroscopy, but only two so-called normal galaxies were included. This is an imbalance that should be corrected, to balance Herschel's legacy.

  6. Oxytocin (OT) and arginine-vasopressin (AVP) act on OT receptors and not AVP V1a receptors to enhance social recognition in adult Syrian hamsters (Mesocricetus auratus).

    Science.gov (United States)

    Song, Zhimin; Larkin, Tony E; Malley, Maureen O'; Albers, H Elliott

    2016-05-01

    Social recognition is a fundamental requirement for all forms of social relationships. A majority of studies investigating the neural mechanisms underlying social recognition in rodents have investigated relatively neutral social stimuli such as juveniles or ovariectomized females over short time intervals (e.g., 2h). The present study developed a new testing model to study social recognition among adult males using a potent social stimulus. Flank gland odors are used extensively in social communication in Syrian hamsters and convey important information such as dominance status. We found that the recognition of flank gland odors after a 3min exposure lasted for at least 24h, substantially longer than the recognition of other social cues in rats and mice. Intracerebroventricular injections of OT and AVP prolonged the recognition of flank gland odor for up to 48h. Selective OTR but not V1aR agonists, mimicked these enhancing effects of OT and AVP. Similarly, selective OTR but not V1aR antagonists blocked recognition of the odors after 20min. In contrast, the recognition of non-social stimuli was not blocked by either the OTR or the V1aR antagonists. Our findings suggest both OT and AVP enhance social recognition via acting on OTRs and not V1aRs and that the recognition enhancing effects of OT and AVP are limited to social stimuli. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. The potential for oxytocin (OT) to prevent breast cancer: a hypothesis.

    Science.gov (United States)

    Murrell, T G

    1995-08-01

    This hypothesis proposes that carcinogens in the breast are generated by the action of superoxide free radicals released when acinal gland distension, under the influence of unopposed prolactin, causes microvessel ischaemia. Inadequate nipple care in the at-risk years leads to ductal obstruction preventing the elimination of carcinogens from the breast. The regular production of oxytocin (OT) from nipple stimulation would cause contraction of the myoepithelial cells, relieving acinal gland distension and aiding the active elimination of carcinogenic fluid from the breast. Mechanical breast pump stimulation causes an increase in plasma OT levels in the luteal but not in the follicular phase of the menstrual cycle. OT production upon nipple stimulation in the luteal phase of premenopausal, non-lactating women may be protective against the high rates of mitotic breast cell division noted at this time via the potential to block the effect of oestrogen. The epidemiology of breast cancer suggests that lengthy lactation time is beneficial. Sexual activity in nulliparous women also protects and OT levels have been shown to rise with orgasm in women and in men. OT systems in the brain are intricately linked to oestrogen and progesterone levels, and it is possible that these hormones may modify the OT secretory response both centrally and through an effect on the sensitivity of the breast. OT production with nipple care and in sex and lactation, and the reduction in cycling ovarian hormones that occurs with pregnancy, may all be important preventative factors in the development of breast cancer both pre- and post-menopausally.

  8. Performance of non-ideal OT-MRC with co-channel interference

    KAUST Repository

    Radaydeh, Redha Mahmoud Mesleh

    2010-12-01

    This paper studies the effect of non-ideal estimation of channel state information (CSI) on the performance of output-threshold maximal-ratio combining (OT-MRC) diversity scheme in the presence of co-channel interference as well as white noise. The channel fading envelopes are assumed to follow slowly varying flat Rayleigh model. New closed-form expressions for the combined signal-to-interference-plus-noise ratio (SINR) distribution and outage probability performance are presented. Performance comparisons between the conventional MRC and OT-MRC for the system model described above are provided. © 2010 IEEE.

  9. MASTER OT J072007.30+451611.6: Cataclysmic Variable with an Extreme Hot Spot

    Science.gov (United States)

    Denisenko, D.

    2018-05-01

    MASTER team has reported an unusual object MASTER OT J072007.30+451611.6 in ATel #11620 (T. Pogrosheva et al.). The object was observed at 17.0-17.2m during 9 minutes from 22:15:26 to 22:24:30 UT on 2018-04-26, but was below the detection limit (18.8m) 45 minutes before the first positive observation and 43 minutes after the last one. As noted by S. Otero in AAVSO VSX entry, MASTER OT J072007.30+451611.6 has an X-ray counterpart XMMSL2 J072007.4+451615.

  10. 12 CFR 502.28 - How does OTS determine the organizational form component for a savings and loan holding company?

    Science.gov (United States)

    2010-01-01

    ... component for a savings and loan holding company? 502.28 Section 502.28 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies... savings and loan holding company that OTS regulates under section 10(l) of the HOLA. OTS will compute your...

  11. Optimal Diphthongs: An OT Analysis of the Acquisition of Spanish Diphthongs

    Science.gov (United States)

    Krause, Alice

    2013-01-01

    This dissertation investigates the acquisition of Spanish diphthongs by adult native speakers of English. The following research questions will be addressed: 1) How do adult native speakers of English pronounce sequences of two vowels in their L2 Spanish at different levels of acquisition? 2) Can OT learnability models, specifically the GLA,…

  12. 12 CFR 563b.200 - What actions may OTS take on my application?

    Science.gov (United States)

    2010-01-01

    ... appraiser may serve as an underwriter or selling agent, if you ensure that the appraiser is separate from the underwriter or selling agent affiliate and the underwriter or selling agent affiliate does not... convenience and needs of your communities after the conversion. (1) Based on this review, OTS may approve your...

  13. Use of thermal cycling to reduce adhesion of OTS coated coated MEMS cantilevers

    Science.gov (United States)

    Ali, Shaikh M.; Phinney, Leslie M.

    2003-01-01

    °Microelectromechanical systems (MEMS) have enormous potential to contribute in diverse fields such as automotive, health care, aerospace, consumer products, and biotechnology, but successful commercial applications of MEMS are still small in number. Reliability of MEMS is a major impediment to the commercialization of laboratory prototypes. Due to the multitude of MEMS applications and the numerous processing and packaging steps, MEMS are exposed to a variety of environmental conditions, making the prediction of operational reliability difficult. In this paper, we investigate the effects of operating temperature on the in-use adhesive failure of electrostatically actuated MEMS microcantilevers coated with octadecyltrichlorosilane (OTS) films. The cantilevers are subjected to repeated temperature cycles and electrostatically actuated at temperatures between 25°C and 300°C in ambient air. The experimental results indicate that temperature cycling of the OTS coated cantilevers in air reduces the sticking probability of the microcantilevers. The sticking probability of OTS coated cantilevers was highest during heating, which decreased during cooling, and was lowest during reheating. Modifications to the OTS release method to increase its yield are also discussed.

  14. Spectroscopic Classification of MASTER OT J110707.62-052244.0 as a Type Ia Supernova

    Science.gov (United States)

    Zheng, W.; Kim, M.; Shivvers, I.; Yuk, H.; Filippenko, A. V.

    2015-11-01

    We report that inspection of a CCD spectrum (range 350-1050 nm) of MASTER OT J110707.62-052244.0 (ATel #8236), obtained on Nov. 11.57 UT with the Shane 3-m reflector (+ Kast spectrograph) at Lick Observatory, shows that the object is a normal Type Ia supernova roughly 1 week past maximum brightness.

  15. Spectroscopic Classification of MASTER OT J044212.20+230616.7

    Science.gov (United States)

    Shivvers, I.; Kelly, P. L.; Clubb, K. I.; Filippenko, A. V.

    2014-09-01

    We report that inspection of a CCD spectrum (range 330-1000 nm), obtained on September 22 UT with the 3-m Shane reflector (+ Kast) at Lick Observatory, shows that MASTER OT J044212.20+230616.7 (ATel #6484) is a Type IIn supernova.

  16. 78 FR 54401 - Removal of Transferred OTS Regulations Regarding Post-Employment Activities of Senior Examiners

    Science.gov (United States)

    2013-09-04

    ... F Street) on business days between 7 a.m. and 5 p.m. Please include your name, affiliation, address... section 6303(b) of the Intelligence Reform and Terrorism Prevention Act of 2004.\\4\\ This Act added a new... showing of good cause. After comparing the FDIC's rules with the transferred OTS rule relating to post...

  17. Nedožité devadesátiny Milana Otáhala

    Czech Academy of Sciences Publication Activity Database

    Tůma, Oldřich

    2017-01-01

    Roč. 24, 1/2 (2017), s. 247-251 ISSN 1210-7050 Institutional support: RVO:68378114 Keywords : Milan Otáhal * obituary * historiography Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  18. Doktoritööd : [2007, Janis Ešots, Signe Dobelniece

    Index Scriptorium Estoniae

    2007-01-01

    29. mail kaitseb Janis Ešots doktoritööd "Mullā Sadrā wujūd õpetus: müstitsismi ja filosoofia süntees"; 11. juunil kaitseb Signe Dobelniece doktoritööd "Kodutus Lätis: põhjused ja lahendused"

  19. "Merging Yoga and Occupational Therapy (MY-OT): A feasibility and pilot study".

    Science.gov (United States)

    Schmid, Arlene A; Puymbroeck, Marieke Van; Portz, Jennifer D; Atler, Karen E; Fruhauf, Christine A

    2016-10-01

    To examine the feasibility and benefits of the Merging Yoga and Occupational Therapy (MY-OT) intervention. This is the primary analysis of a non-controlled pretest-posttest pilot study to understand the feasibility and impact of MY-OT on balance, balance self-efficacy, and fall risk factor management in people with chronic stroke. University research laboratory. People with chronic stroke were included in the study if they: had sustained a fall or had fear of falling, were able to stand, and hand impaired balance and were at risk for falls (≤46 on the Berg Balance Scale (BBS)). Individuals completed an 8 week intervention that included 16 sessions of both yoga and group occupational therapy (OT). Yoga included physical postures, breathing exercises, and meditation. OT focused on post-stroke fall risk factor management. The BBS was used to assess balance, the Activities-specific Balance Confidence Scale (ABC) was used to measure balance self-efficacy. Five fall risk factor management scales were used. Overall, the intervention was considered feasible, as individuals were able to safely complete the intervention with little attrition and high attendance. Balance improved by 30% (p=0.002). Balance self-efficacy improved by 15% (p=0.034). Each of the five fall risk factor management scales improved, but only two significantly improved (Fall Prevention and Management Questionnaire, 29%, p=0.004 and Fall Prevention Strategy Survey, 42%, p=0.032). The results demonstrate that MY-OT is a potential intervention to improve multiple fall related outcomes for people with stroke. Therapists may consider these interventions for people with stroke, but additional research is warranted. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. PREDICTING PROGNOSTIC VALUE OF OCULAR TRAUMA SCORE (OTS IN AN OPEN GLOBE INJURY IN TERTIARY EYE CARE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Rahul

    2015-10-01

    Full Text Available AIM : To evaluate the prognostic value of OTS in open globe injuries. MATERIAL METHOD : Retrospective analysis of 77 eyes with open globe injuries was done from 01/07/2013 to 31/12/2014. Patients were assigned raw score sum based on initial V/A, and ocular findings then classified into 5 categories for predicting final visual outcome based on ocular Trauma score (OTS. RESULT : We estimated final V/A in 77 cases of open globe injuries (64.93% had raw sc ore between 65.91 (category 3, 4 Six months after the injury, 42.85% patients of categories 1 (raw score 0 - 44 achieved V/A of PL/HM as compared to 17% in OTS study. 16 patients with raw compared to OTS study. We reported comparable visual outcome with OT S study except in category 1 & 2. CONCLUSION: OTS score is valuable in triage, patient counseling and decision making for the management of ocular trauma. We recommend that OTS should be used routinely for open globe injuries as it is a simple guide

  1. MASTER OT J014638.27+041324.4 is a Young Type IIP Supernova

    Science.gov (United States)

    Zheng, W.; Kelly, P. L.; Clubb, K. I.; Filippenko, A. V.

    2013-12-01

    We report that a CCD spectrum (range 350-1000 nm) of MASTER OT J014638.27+041324.4 (Shurpakov et al., ATel #5630) was obtained on Dec 6.5 UT with the Shane 3-m reflector (+Kast spectrograph) at Lick Observatory. The spectrum shows a blue continuum and weak, broad hydrogen Balmer lines having P-Cyg profiles, indicating that the object is a young Type IIP supernova. Weak He I 587.6 nm is also present.

  2. Mis mõtteid tekitab õpetaja kutsestandardi projekt? / Kerli Prass, Kalle Kalda, Loone Ots, Külli Arand

    Index Scriptorium Estoniae

    2013-01-01

    Vastasid SA Noored Kooli tuutor ja õpetajakoolituse koordinaator Kerli Prass, lastekaitse liidu president Loone Ots, Tartu haridustöötajate liidu esimees Kalle Kalda, Tallinna Saksa Gümnaasiumi klassiõpetaja Külli Arand

  3. Computer software design description for the Treated Effluent Disposal Facility (TEDF), Project L-045H, Operator Training Station (OTS)

    International Nuclear Information System (INIS)

    Carter, R.L. Jr.

    1994-01-01

    The Treated Effluent Disposal Facility (TEDF) Operator Training Station (OTS) is a computer-based training tool designed to aid plant operations and engineering staff in familiarizing themselves with the TEDF Central Control System (CCS)

  4. Placental Expressions of CDKN1C and KCNQ1OT1 in Monozygotic Twins with Selective Intrauterine Growth Restriction.

    Science.gov (United States)

    Gou, Chenyu; Liu, Xiangzhen; Shi, Xiaomei; Chai, Hanjing; He, Zhi-Ming; Huang, Xuan; Fang, Qun

    2017-10-01

    CDKN1C and KCNQ1OT1 are imprinted genes that might be potential regulators of placental development. This study investigated placental expressions of CDKN1C and KCNQ1OT1 in monozygotic twins with and without selective intrauterine growth restriction (sIUGR). Seventeen sIUGR and fifteen normal monozygotic(MZ) twin pairs were examined. Placental mRNA expressions of CDKN1C and KCNQ1OT1 were detected by real-time fluorescent quantitative PCR. CDKN1C protein expression was detected by immunohistochemical assay and Western-blotting. In the sIUGR group, smaller fetuses had a smaller share of the placenta, and CDKN1C protein expression was significantly increased while KCNQ1OT1 mRNA expression was significantly decreased. The CDKN1C/KCNQ1OT1 mRNA ratio was lower in the larger fetus than in the smaller fetus (p < .05). In the control group, CDKN1C protein expression showed no difference between larger and smaller fetuses, while KCNQ1OT1 mRNA expression was significantly lower in the larger fetus, and the CDKN1C/KCNQ1OT1 mRNA ratio was higher in the larger fetus than in the smaller fetus (p < .05). Our findings showed that pathogenesis of sIUGR may be related to the co-effect of the up-regulated protein expression of CDKN1C and down-regulated mRNA expression of KCNQ1OT1 in the placenta.

  5. Gene expression profiles of prohibitin in testes of Octopus tankahkeei (ot-phb) revealing its possible role during spermiogenesis.

    Science.gov (United States)

    Mao, Hai-Tao; Wang, Da-Hui; Lan, Zhou; Zhou, Hong; Yang, Wan-Xi

    2012-05-01

    Prohibitin is essential for intracellular homeostasis and stabilization of mitochondrial respiratory chain complexes. To explore its functions during spermiogenesis of Octopus tankahkeei (O. tankahkeei), we have cloned and sequenced the cDNA of this mammalian PHB homologue (termed ot-PHB) from the testes of O. tankahkeei. The 1165 bp ot-phb cDNA contains a 100 bp 5' UTR, a 882 bp open reading frame and a 183 bp 3' UTR. The putative ot-PHB protein owns a transmembrane domain from 6 to 31 amino acid (aa) and a putative PHB domain from 26 to 178 aa. Protein alignment demonstrated that ot-PHB had 73.3, 73.6, 74.0, 75.1, and 45.4% identity with its homologues in Homo sapiens, Mus muculus, Danio rerio, Xenopus tropicalis and Trypanosoma brucei, respectively. Tissue distribution profile analysis revealed its presence in all the tissues examined. In situ hybridization in spermiogenic cells demonstrated that ot-phb was expressed moderately at the beginning of the spermiogenesis. The abundance of transcripts increased in intermediate spermatids and in drastically remodeling final spermatids. In mature spermatozoa, the residuary transcripts concentrated around the chondriosomal mantle where mitochondria assemble around. In summary, the expression of ot-phb during spermiogenesis implicates a potential function of this protein during mitochondrial ubiquitination. It is the first time to implicate the role of prohibitin in cephalopod spermiogenesis.

  6. The reactivity of anion-exchange resins by applying OT-for-OH exchange reaction in the equilibrium state

    International Nuclear Information System (INIS)

    Kano, Naoki; Nihei, Makoto; Imaizumi, Hiroshi

    1996-01-01

    In order to reveal the behavior of hydroxyl group in isotope exchange reaction, OT-for-OH exchange reaction between each anion-exchange resin (OH - form) and tritiated water (abbreviated as HTO water below) was observed at 80degC under the equilibrium. Anion-exchange resins used were Amberlite IRA-400, IRA-410 (both strongly basic), and IRA-94S (weakly basic). It can be thought that an HTO molecule dissociates into H + +OT - (or T + +OH - ). The activity of each resin based on OT-for-OH exchange reaction was measured with a liquid scintillation counter. From the above-mentioned, the following five were found. Isotope exchange reaction as 'atomic group' occurred between the OH group in each anion-exchange resin and the OT group in HTO water. The reactivity of strongly basic anion-exchange resin is larger than that of weakly basic one. The ratio of the reactivity of these resins can roughly be expressed as follows: (IRA-410): (IRA-400): (IRA-94S)=42: 7: 1. The degree of OT-for-OH exchange reaction may be smaller than that of T-for-H exchange reaction. The method used and results obtained in this work may be helpful to obtain the data for the prevention of T-contamination, especially to obtain the data from certain atomic groups including T. (author)

  7. Solar-energy-system performance evaluation: Honeywell OTS 44, Ocmulgee, Georgia

    Science.gov (United States)

    Mathur, A. K.; Pederson, S.

    1982-01-01

    The operation and technical performance of the solar operational test site (OTS 44) are described, based on data collected between April, 1981 and August, 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 44 is a hydronic heating and cooling system consisting of 5040 square feet of liquid cooled flat plate collectors; a 4000 gallon thermal storage tank; one 25 ton capacity organic Rankine cycle engine assisted water chillers; a forced draft cooling tower; and associated piping, pumps, valves, controls and heat rejection equipment. The solar system has eight basic modes of operation and several combination modes for providing space conditioning and hot water to the building. Data monitored during the 4 months of the operational test period found that the solar system collected 285 MMBtu of thermal energy of the total incident solar energy of 1040 MMBtu and provided 210 MMBtu for cooling and 10 MMBtu for heating and hot water. The net electrical energy saving due to the solar system was approximately 2600 kWh(e), and fossil energy saving was about 20 million Btu (MMBtu).

  8. Solar energy system performance evaluation: Honeywell OTS 41, Shenandoah (Newman), Georgia

    Science.gov (United States)

    Mathur, A. K.; Pederson, S.

    1982-08-01

    The operation and technical performance of the Solar Operational Test Site (OTS 41) located at Shenandoah, Georgia, are described, based on the analysis of the data collected between January and August 1981. The following topics are discussed: system description, performance assessment, operating energy, energy savings, system maintenance, and conclusions. The solar energy system at OTS 41 is a hydronic heating and cooling system consisting of 702 square feet of liquid-cooled flat-plate collectors; a 1000-gallon thermal storage tank; a 3-ton capacity organic Rankine-cycle-engine-assisted air conditioner; a water-to-are heat exchanger for solar space heating; a finned-tube coil immersed in the storage tank to preheat water for a gas-fired hot water heater; and associated piping, pumps, valves, and controls. The solar system has six basic modes of operation and several combination modes. The system operation is controlled automatically by a Honeywell-designed microprocessor-based control system, which also provides diagnostics.

  9. In a changing society which elements and competencies is needed and demanded in the future OT education?

    DEFF Research Database (Denmark)

    Hansen, Bodil Winther; Sørensen, Annette

    to plan a curriculum, in order to enable OT graduates to meet employers’ demands in a rapidly changing society •The future OT profession. After 12 years of practising Problem Based Learning (PBL), the Faculty of Occupational Therapy wanted to develop the quality of the OT education offered by Metropolitan...... University College, Copenhagen. The object was to evaluate and develop the pedagogical practice, and to examine if the pedagogical concept prepares the students for the future in the best way possible. To describe the level of education to be achieved in terms of competences and learning outcome, the study...... was inspired by the Tuning Process of educational structures in Europe, which is part of the Bologna process to integrate higher education in Europe. The study is based on literature studies, quantitative and qualitative methods. All of these methods are suitable for uncovering competences demanded by practice...

  10. High-Amplitude, Rapid Photometric Variation of the New Polar Master OT J132104.0+560957.8

    Science.gov (United States)

    2015-02-05

    HIGH-AMPLITUDE, RAPID PHOTOMETRIC VARIATION OF THE NEW POLAR MASTER OT J132104.04+560957.8 LITTLEFIELD, COLIN;1,2 GARNAVICH, PETER;1 MAGNO, KATRINA;1...18.5 during each photometric cycle, becoming so faint that we could no longer detect it. The data showed a period of roughly 91 minutes with each...TYPE 3. DATES COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE High-Amplitude, Rapid Photometric Variation Of The New Polar Master OT

  11. Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice.

    Directory of Open Access Journals (Sweden)

    Jan Korte

    2016-12-01

    Full Text Available Trehalose biosynthesis is considered an attractive target for the development of antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium tuberculosis. The most common biosynthetic route involves trehalose-6-phosphate (T6P synthase OtsA and T6P phosphatase OtsB that generate trehalose from ADP/UDP-glucose and glucose-6-phosphate. In order to assess the drug target potential of T6P phosphatase, we generated a conditional mutant of M. tuberculosis allowing the regulated gene silencing of the T6P phosphatase gene otsB2. We found that otsB2 is essential for growth of M. tuberculosis in vitro as well as for the acute infection phase in mice following aerosol infection. By contrast, otsB2 is not essential for the chronic infection phase in mice, highlighting the substantial remodelling of trehalose metabolism during infection by M. tuberculosis. Blocking OtsB2 resulted in the accumulation of its substrate T6P, which appears to be toxic, leading to the self-poisoning of cells. Accordingly, blocking T6P production in a ΔotsA mutant abrogated otsB2 essentiality. T6P accumulation elicited a global upregulation of more than 800 genes, which might result from an increase in RNA stability implied by the enhanced neutralization of toxins exhibiting ribonuclease activity. Surprisingly, overlap with the stress response caused by the accumulation of another toxic sugar phosphate molecule, maltose-1-phosphate, was minimal. A genome-wide screen for synthetic lethal interactions with otsA identified numerous genes, revealing additional potential drug targets synergistic with OtsB2 suitable for combination therapies that would minimize the emergence of resistance to OtsB2 inhibitors.

  12. Characterization of an immunodominant cancer-specific O-glycopeptide epitope in murine podoplanin (OTS8)

    DEFF Research Database (Denmark)

    Steentoft, Catharina; Schjoldager, Katrine T; Cló, Emiliano

    2010-01-01

    antibody 237, developed to a spontaneous murine fibrosarcoma, was shown to be directed to murine podoplanin (OTS8) with truncated Tn O-glycans. Our understanding of such cancer-specific auto-antibodies to truncated glycoforms of glycoproteins is limited. Here we have investigated immunogenicity...... of a chemoenzymatically produced Tn-glycopeptide derived from the putative murine podoplanin O-glycopeptide epitope. We found that the Tn O-glycopeptide was highly immunogenic in mice and produced a Tn-glycoform specific response with no reactivity against unglycosylated peptides or the O-glycopeptide with extended O......-glycan (STn and T glycoforms). The immunodominant epitope was strictly dependent on the peptide sequence, required Tn at a specific single Thr residue (Thr(77)), and antibodies to the epitope were not found in naive mice. We further tested a Tn O-glycopeptide library derived from human podoplanin...

  13. Entraining IDyOT: timing in the information dynamics of thinking

    Directory of Open Access Journals (Sweden)

    Jamie Forth

    2016-10-01

    Full Text Available We present a novel hypothetical account of entrainment in music and language, in context of the Information Dynamics of Thinking model, IDyOT. The extended model affords an alternative view of entrainment, and its companion term, pulse, from earlier accounts. The model is based on hiearchical, statistical prediction, modeling expectations of both what an event will be and when it will happen. As such,it constitutes a kind of predictive coding, with a particular novel hypothetical implementation. Here, we focus on the model’s mechanism for predicting when a perceptual event will happen, given an existing sequence of past events, which maybe musical or linguistic. We propose a range of tests to validate or falsify the model, at various different levels of abstraction, and argue that computational modelling in particular, and this model in particular, can offer a means of providing limited but useful evidence for evolutionary hypotheses.

  14. 75 FR 181 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    Science.gov (United States)

    2010-01-04

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Application for Conversion From: (a) OTS-Regulated, State- Chartered Savings Association to Federal Savings Association; (b) National Bank, Commercial Bank, State Savings Bank, or Credit Union to Federal Savings Association; (c) State Mutual Holding...

  15. 75 FR 10560 - Application for Conversion From: (a) OTS-Regulated, State-Chartered Savings Association to...

    Science.gov (United States)

    2010-03-08

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision Application for Conversion From: (a) OTS-Regulated, State- Chartered Savings Association to Federal Savings Association; (b) National Bank, Commercial Bank, State Savings Bank, or Credit Union to Federal Savings Association; (c) State Mutual Holding...

  16. 12 CFR 502.29 - How does OTS determine the condition component for a savings and loan holding company?

    Science.gov (United States)

    2010-01-01

    ... for a savings and loan holding company? 502.29 Section 502.29 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies-Calculation of Assessments § 502.29 How does OTS determine the condition component for a savings and loan...

  17. 12 CFR 502.26 - How does OTS calculate the semi-annual assessment for savings and loan holding companies?

    Science.gov (United States)

    2010-01-01

    ... assessment for savings and loan holding companies? 502.26 Section 502.26 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE TREASURY ASSESSMENTS AND FEES Assessments Savings and Loan Holding Companies-Calculation of Assessments § 502.26 How does OTS calculate the semi-annual assessment for savings and loan...

  18. Effect of Ozone Therapy (OT on Healing of Colonic Anastomosis in a Rat Model of Peritonitis

    Directory of Open Access Journals (Sweden)

    Başak Erginel

    2014-09-01

    Full Text Available Background: Ozone is a three-oxygen molecule (O3. Ozone therapy (OT is systematically effective when pathological inflammatory and immunologic processes are activated. Among of these conditions are wound healing, macular degeneration related to aging, and conditions that are ischemic or infectious. Aims: The aim of this study was to determine the effects of OT on wound healing of intestinal anastomosis in the presence of peritonitis in a rat model. Study Design: Animal experimentation. Methods: A total of 40 Wistar albino rats were randomized into four groups (n=10 including: sham (S, peritonitis (P, ozone 0 (O0, and ozone 24 (O24. In group S, only cecal dissection was carried out. The S group had only a cecal dissection and intestinal anastomosis performed, but no peritonitis. In all other groups, cecal ligation and puncture (CLP followed the cecal dissection to induce bacterial peritonitis. 24 h after puncture, a cecal resection and ileocolic anastomosis were performed. In group P, 24 h after CLP, a cecal resection and ileocolic anastomosis were performed and no ozone was administered. In group O0, immediately after the anastomosis, and in group O24, starting 24 hours after the anastomosis, an intraperitoneal 1 mg/kg/day ozone administration was applied for seven days. On the seventh day the animals were sacrificed, the anastomotic bursting pressures (BP and the hydroxyproline values of the anastomotic tissues were measured, and histopathologic examination of the anastomotic segment was carried out. Results: The highest BP was in group S, with 211±23.13 mmHg. The mean BP of group P was 141±56.25 mmHg, which was significantly lower than in the other two peritonitis groups that received ozone therapy, group O0 and O24, where it was 192±22 and 166±45 mmHg, respectively (p0.05. Histopathologic analyses of the anastomotic segments determined there was significantly more oedema and necrosis in the control group rats, and collagen deposition in

  19. Over-expression of the mycobacterial trehalose-phosphate phosphatase OtsB2 results in a defect in macrophage phagocytosis associated with increased mycobacterial-macrophage adhesion

    Directory of Open Access Journals (Sweden)

    Hao Li

    2016-11-01

    Full Text Available Trehalose-6-phosphate phosphatase (OtsB2 is involved in the OtsAB trehalose synthesis pathway to produce free trehalose and is strictly essential for mycobacterial growth. We wished to determine the effects of OtsB2 expression on mycobacterial phenotypes such as growth, phagocytosis and survival in macrophages. Mycobacterium bovis-BCG (BCG over-expressing OtsB2 were able to better survive in stationary phase. Over-expression of OtsB2 led to a decrease in phagocytosis but not survival in THP-1 macrophage-like cells, and this was not due to a decrease in general macrophage phagocytic activity. Surprisingly, when we investigated macrophage-mycobacterial interactions by flow cytometry and atomic force microscopy, we discovered that BCG over-expressing OtsB2 have stronger binding to THP-1 cells than wild-type BCG. These results suggest that altering OtsB2 expression has implications for mycobacterial host-pathogen interactions. Macrophage-mycobacteria phagocytic interactions are complex and merit further study.

  20. Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

    Directory of Open Access Journals (Sweden)

    Carmel M. Barber

    2016-02-01

    Full Text Available Taipans (Oxyuranus spp. are elapids with highly potent venoms containing presynaptic (β and postsynaptic (α neurotoxins. O. temporalis (Western Desert taipan, a newly discovered member of this genus, has been shown to possess venom which displays marked in vitro neurotoxicity. No components have been isolated from this venom. We describe the characterization of α-elapitoxin-Ot1a (α-EPTX-Ot1a; 6712 Da, a short-chain postsynaptic neurotoxin, which accounts for approximately 30% of O. temporalis venom. α-Elapitoxin-Ot1a (0.1–1 µM produced concentration-dependent inhibition of indirect-twitches, and abolished contractile responses to exogenous acetylcholine and carbachol, in the chick biventer cervicis nerve-muscle preparation. The inhibition of indirect twitches by α-elapitoxin-Ot1a (1 µM was not reversed by washing the tissue. Prior addition of taipan antivenom (10 U/mL delayed the neurotoxic effects of α-elapitoxin-Ot1a (1 µM and markedly attenuated the neurotoxic effects of α-elapitoxin-Ot1a (0.1 µM. α-Elapitoxin-Ot1a displayed pseudo-irreversible antagonism of concentration-response curves to carbachol with a pA2 value of 8.02 ± 0.05. De novo sequencing revealed the main sequence of the short-chain postsynaptic neurotoxin (i.e., α-elapitoxin-Ot1a as well as three other isoforms found in O. temporalis venom. α-Elapitoxin-Ot1a shows high sequence similarity (i.e., >87% with other taipan short-chain postsynaptic neurotoxins.

  1. A global outer-rise/outer-trench-slope (OR/OTS) earthquake study

    Science.gov (United States)

    Wartman, J. M.; Kita, S.; Kirby, S. H.; Choy, G. L.

    2009-12-01

    Using improved seismic, bathymetric, satellite gravity and other geophysical data, we investigated the seismicity patterns and focal mechanisms of earthquakes in oceanic lithosphere off the trenches of the world that are large enough to be well recorded at teleseismic distances. A number of prominent trends are apparent, some of which have been previously recognized based on more limited data [1], and some of which are largely new [2-5]: (1) The largest events and the highest seismicity rates tend to occur where Mesozoic incoming plates are subducting at high rates (e.g., those in the western Pacific and the Banda segment of Indonesia). The largest events are predominantly shallow normal faulting (SNF) earthquakes. Less common are reverse-faulting (RF) events that tend to be deeper and to be present along with SNF events where nearby seamounts, seamount chains and other volcanic features are subducting [Seno and Yamanaka, 1996]. Blooms of SNF OR/OTS events usually occur just after and seaward of great interplate thrust (IPT) earthquakes but are far less common after smaller IPT events. (2) Plates subducting at slow rates (Chile, the Ninety East Ridge in Sumatra, and the D’Entrecastaux Ridge in Vanuatu).

  2. Evaluation of a Coaching Experiential Learning Project on OT Student Abilities and Perceptions

    Directory of Open Access Journals (Sweden)

    Erin A. Phillips

    2017-01-01

    Full Text Available Innovative teaching methods to address emerging practice needs are critical components of effective occupational therapy education. Experiential learning strategies can enhance skill development and translation of knowledge into OT clinical practice. In addition, skills such as coaching may provide important links to health promotion practices. Thirty-two occupational therapy students took part in an experiential project to connect occupational engagement and health for a community of older adults. A pretest/posttest design was used to evaluate program outcomes in student perceived abilities, and narrative reflection papers provided postexperience qualitative information. The students improved in all 10 areas of abilities selfassessment with mean total scores from pretest (M = 42 improving significantly at posttest (M = 58. Themes from reflection papers indicated a positive response to experiential learning and a desire for more opportunities to prepare for clinical practice, including the use of interprofessional training. The students improved in their abilities to use coaching and health promotion strategies through the use of experiential learning methods. Outcomes suggest that experiential learning opportunities are an effective way to enhance student competencies in coaching, improve readiness for wellness programming, and increase student confidence in application of skills in future clinical practice.

  3. Secondary Metabolite Profiling of Species of the Genus Usnea by UHPLC-ESI-OT-MS-MS

    Directory of Open Access Journals (Sweden)

    Francisco Salgado

    2017-12-01

    Full Text Available Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria, which are considered among the slowest growing organisms, with strong tolerance to adverse environmental conditions. There are about 400 genera and 1600 species of lichens and those belonging to the Usnea genus comprise about 360 of these species. Usnea lichens have been used since ancient times as dyes, cosmetics, preservatives, deodorants and folk medicines. The phytochemistry of the Usnea genus includes more than 60 compounds which belong to the following classes: depsides, depsidones, depsones, lactones, quinones, phenolics, polysaccharides, fatty acids and dibenzofurans. Due to scarce knowledge of metabolomic profiles of Usnea species (U. barbata, U. antarctica, U. rubicunda and U. subfloridana, a study based on UHPLC-ESI-OT-MS-MS was performed for a comprehensive characterization of their secondary metabolites. From the methanolic extracts of these species a total of 73 metabolites were identified for the first time using this hyphenated technique, including 34 compounds in U. barbata, 21 in U. antarctica, 38 in U. rubicunda and 37 in U. subfloridana. Besides, a total of 13 metabolites were not identified and reported so far, and could be new according to our data analysis. This study showed that this hyphenated technique is rapid, effective and accurate for phytochemical identification of lichen metabolites and the data collected could be useful for chemotaxonomic studies.

  4. {sigma}{sup t}ot{sub e}eyy at e{sup +}e{sup -} colliders

    Energy Technology Data Exchange (ETDEWEB)

    Godbole, R.M. [Indian Institute of Science, Centre for Theoretical Studies, Bangalore (India); Pancheri, G. [Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Frascati, Rome (Italy)

    2001-02-01

    In this talk are briefly summarized different models for {sigma}{sup t}ot{sub 2}y (e{sup +}e{sup -} {yields}yy{yields} hadrons) and contrast model predictions with the data. It will be then discussed the capability of the future e{sup +}e{sup -} and yy colliders to distinguish between various models and end with an outlook for future work.

  5. Treatment of geographic atrophy by the topical administration of OT-551: results of a phase II clinical trial.

    Science.gov (United States)

    Wong, Wai T; Kam, Waynekid; Cunningham, Denise; Harrington, Molly; Hammel, Keri; Meyerle, Catherine B; Cukras, Catherine; Chew, Emily Y; Sadda, Srinivas R; Ferris, Frederick L

    2010-12-01

    To investigate the safety and preliminary efficacy of OT-551, a disubstituted hydroxylamine with antioxidant properties, for the treatment of geographic atrophy (GA), the advanced atrophic form of age-related macular degeneration (AMD). The study was a single-center, open-label phase II trial, enrolling 10 participants with bilateral GA. Topical 0.45% OT-551 was administered in one randomly assigned eye three times daily for 2 years. Safety measures were assessed by complete ophthalmic examination, fundus photography, and review of symptoms. The primary efficacy outcome measure was the change in best corrected visual acuity at 24 months. Secondary efficacy measures included changes in area of GA, contrast sensitivity, microperimetry measurements, and total drusen area from baseline. Study drug was well tolerated and was associated with few adverse events. The mean change in BCVA at 2 years was +0.2 ± 13.3 letters in the study eyes and -11.3 ± 7.6 letters in fellow eyes (P = 0.0259). However, no statistically significant differences were found between the study and fellow eyes for all other secondary outcome measures. OT-551 was well tolerated by study participants and was not associated with any serious adverse effects. Efficacy measurements in this small study indicate a possible effect in maintaining visual acuity. However, the absence of significant effects on other outcomes measures in this study suggests that OT-551, in the current concentration and mode of delivery, may have limited or no benefit as a treatment for GA (ClinicalTrials.gov number, NCT00306488).

  6. The R package otu2ot for implementing the entropy decomposition of nucleotide variation in sequence data

    Directory of Open Access Journals (Sweden)

    Alban eRamette

    2014-11-01

    Full Text Available Oligotyping is a novel, supervised computational method that classifies closely related sequences into oligotypes (OTs based on subtle nucleotide variations (Eren et al. 2013. Its application to microbial datasets has helped reveal ecological patterns which are often hidden by the way sequence data are currently clustered to define operational taxonomic units (OTUs. Here, we implemented the OT entropy decomposition procedure and its unsupervised version, Minimal Entropy Decomposition (MED; Eren et al. 2014, in the statistical programming language and environment, R. The aims are to facilitate the integration of computational routines, interactive statistical analyses, and visualization into a single framework. In addition, two complementary approaches are implemented: 1 An analytical method (the broken stick model is proposed to help identify oligotypes of low abundance that could be generated by chance alone and 2 a one-pass profiling (OP method, to efficiently identify those OTUs whose subsequent oligotyping would be most promising. These enhancements are especially useful for large datasets, where a manual screening of entropy analysis results and the creation of a full set of OTs may not be feasible. The package and procedures are illustrated by several tutorials and examples.

  7. Transcriptional role of androgen receptor in the expression of long non-coding RNA Sox2OT in neurogenesis.

    Directory of Open Access Journals (Sweden)

    Valentina Tosetti

    Full Text Available The complex architecture of adult brain derives from tightly regulated migration and differentiation of precursor cells generated during embryonic neurogenesis. Changes at transcriptional level of genes that regulate migration and differentiation may lead to neurodevelopmental disorders. Androgen receptor (AR is a transcription factor that is already expressed during early embryonic days. However, AR role in the regulation of gene expression at early embryonic stage is yet to be determinate. Long non-coding RNA (lncRNA Sox2 overlapping transcript (Sox2OT plays a crucial role in gene expression control during development but its transcriptional regulation is still to be clearly defined. Here, using Bicalutamide in order to pharmacologically inactivated AR, we investigated whether AR participates in the regulation of the transcription of the lncRNASox2OTat early embryonic stage. We identified a new DNA binding region upstream of Sox2 locus containing three androgen response elements (ARE, and found that AR binds such a sequence in embryonic neural stem cells and in mouse embryonic brain. Our data suggest that through this binding, AR can promote the RNA polymerase II dependent transcription of Sox2OT. Our findings also suggest that AR participates in embryonic neurogenesis through transcriptional control of the long non-coding RNA Sox2OT.

  8. VizieR Online Data Catalog: Follow-up photometry of M101 OT2015-1 (Blagorodnova+, 2017)

    Science.gov (United States)

    Blagorodnova, N.; Kotak, R.; Polshaw, J.; Kasliwal, M. M.; Cao, Y.; Cody, A. M.; Doran, G. B.; Elias-Rosa, N.; Fraser, M.; Fremling, C.; Gonzalez-Fernandez, C.; Harmanen, J.; Jencson, J.; Kankare, E.; Kudritzki, R.-P.; Kulkarni, S. R.; Magnier, E.; Manulis, I.; Masci, F. J.; Mattila, S.; Nugent, P.; Ochner, P.; Pastorello, A.; Reynolds, T.; Smith, K.; Sollerman, J.; Taddia, F.; Terreran, G.; Tomasella, L.; Turatto, M.; Vreeswijk, P. M.; Wozniak, P.; Zaggia, S.

    2017-07-01

    The location of M101-OT2015-1 has been serendipitously imaged by numerous telescopes and instruments over the last 15 years (from 2000 to 2015). Our best quality pre-discovery image (seeing of 0.55") is an r-band exposure at -3625 days pre-peak from the Canada-France-Hawaii Telescope (CFHT). The historical optical data for M101-OT was retrieved from the CFHT MegaPrime and CFHT12K/Mosaic, using single and combined exposures, Pan-STARRS-1/GPC1 (PS1), Isaac Newton Telescope/Wide Field Camera (INT/WFC), and Sloan Digital Sky Survey (SDSS) DR 10 (Ahn+ 2014, see V/147). Unfortunately, there are no HST images covering the location of the source. Post-discovery optical magnitudes were obtained from the reported followup astronomer's telegrams (ATels), Liverpool Telescope (LT), the Nordic Optical Telescope (NOT), and the Palomar P48 and P60 telescopes. The infrared data were retrieved from CFHT/WIRCam, UKIRT/WFCAM, and the Spitzer Infrared Array Camera in 3.6 and 4.5um as part of the SPitzer InfraRed Intensive Transients Survey (SPIRITS) (Kasliwal+, 2017ApJ...839...88K). Details of pre-discovery photometry and post-discovery optical photometry may be found in the Appendices Tables 1 and 2, respectively. We obtained spectra of M101-OT using a range of facilities in 2015 Feb-Jul. (3 data files).

  9. Transcriptional analysis and molecular dynamics simulations reveal the mechanism of toxic metals removal and efflux pumps in Lysinibacillus sphaericus OT4b.31

    KAUST Repository

    Shaw, Dario Rangel; Dussan, Jenny

    2017-01-01

    Lysinibacillus sphaericus strain OT4b.31 is a bacterium widely applied in bioremediation processes of hydrocarbon and metal polluted environments. In this study, we identified the molecular mechanism underlying the Pb2+ and Cr6+ resistance. Metal

  10. Multiseasonal Tree Crown Structure Mapping with Point Clouds from OTS Quadrocopter Systems

    Science.gov (United States)

    Hese, S.; Behrendt, F.

    2017-08-01

    OTF (Off The Shelf) quadro copter systems provide a cost effective (below 2000 Euro), flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI) mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on), one in March 2017 (leaf-off) and one in May 2017 (leaf-on) to derive point clouds from different crown structure and phenological situations - covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion) algorithms clearly identified the central stem and also secondary branch systems. While the penetration into the crown

  11. MULTISEASONAL TREE CROWN STRUCTURE MAPPING WITH POINT CLOUDS FROM OTS QUADROCOPTER SYSTEMS

    Directory of Open Access Journals (Sweden)

    S. Hese

    2017-08-01

    Full Text Available OTF (Off The Shelf quadro copter systems provide a cost effective (below 2000 Euro, flexible and mobile platform for high resolution point cloud mapping. Various studies showed the full potential of these small and flexible platforms. Especially in very tight and complex 3D environments the automatic obstacle avoidance, low copter weight, long flight times and precise maneuvering are important advantages of these small OTS systems in comparison with larger octocopter systems. This study examines the potential of the DJI Phantom 4 pro series and the Phantom 3A series for within-stand and forest tree crown 3D point cloud mapping using both within stand oblique imaging in different altitude levels and data captured from a nadir perspective. On a test site in Brandenburg/Germany a beach crown was selected and measured with 3 different altitude levels in Point Of Interest (POI mode with oblique data capturing and deriving one nadir mosaic created with 85/85 % overlap using Drone Deploy automatic mapping software. Three different flight campaigns were performed, one in September 2016 (leaf-on, one in March 2017 (leaf-off and one in May 2017 (leaf-on to derive point clouds from different crown structure and phenological situations – covering the leaf-on and leafoff status of the tree crown. After height correction, the point clouds where used with GPS geo referencing to calculate voxel based densities on 50 × 10 × 10 cm voxel definitions using a topological network of chessboard image objects in 0,5 m height steps in an object based image processing environment. Comparison between leaf-off and leaf-on status was done on volume pixel definitions comparing the attributed point densities per volume and plotting the resulting values as a function of distance to the crown center. In the leaf-off status SFM (structure from motion algorithms clearly identified the central stem and also secondary branch systems. While the penetration into the

  12. Farmakoterapia zaburzeń behawioralnych towarzyszących otępieniu

    Directory of Open Access Journals (Sweden)

    Tomasz Sobów

    2013-12-01

    Full Text Available Farmakoterapia zaburzeń zachowania i objawów neuropsychiatrycznych u chorych otępiałych (behavioural and psychological symptoms of dementia, BPSD była przedmiotem wielu badań klinicznych. Ich wyniki nie pozwalają niestety na sformułowanie prostych zaleceń. Leki przeciwpsychotyczne (zwłaszcza II generacji okazały się względnie skuteczne w zwalczaniu pobudzenia i agresji, ale ich działanie na objawy psychotyczne jest wątpliwe. Poważne obawy dotyczące bezpieczeństwa stosowania leków przeciwpsychotycznych (zwłaszcza ryzyko ostrych zdarzeń sercowo-mózgowych i związanej z nimi śmiertelności w znaczący sposób ograniczają ich wykorzystanie. Leki przeciwdepresyjne, szczególnie z grupy selektywnych inhibitorów zwrotnego wychwytu serotoniny (selective serotonin reuptake inhibitor, SSRI, wykazują podobną skuteczność w zwalczaniu pobudzenia i objawów psychotycznych jak leki przeciwpsychotyczne, co wobec lepszej tolerancji zachęca do ich szerszego stosowania. Inne grupy leków (w tym przeciwdrgawkowe i benzodiazepiny, pomimo teoretycznych przesłanek sugerujących możliwą skuteczność, w randomizowanych badaniach nie zostały ocenione jako wystarczająco efektywne (i bezpieczne, aby rekomendować ich szersze wykorzystanie. Rutynowe stosowanie zasady hierarchicznego postępowania w BPSD (najpierw staranna diagnostyka, w tym wykluczenie majaczenia, następnie interwencje niefarmakologiczne i optymalizacja leczenia inhibitorami cholinesterazy i/lub memantyną, a dopiero w trzeciej kolejności zastosowanie leków psychotropowych pozwala na ograniczenie farmakoterapii w tej szczególnie wrażliwej grupie pacjentów.

  13. Marketingo išlaidų mažinimo efektas post-recesiniu laikotarpiu

    OpenAIRE

    Černikovaitė, Miglė Eleonora; Jucaitytė, Indrė

    2011-01-01

    This article presents the important changes of the post-recession marketing and summarise the scientific research results in Lithuania and foreign countries, demonstrating the effect of reallocating marketing costs. Many of the ongoing studies show that companies that maintain their marketing budgets or increase them during a recession do far better than companies that reduce spending. Despite the fact, the reductions in marketing budget are among the most popular decision of solving short-te...

  14. Characterization of the archaeal ribonuclease P proteins from Pyrococcus horikoshii OT3.

    Science.gov (United States)

    Terada, Atsushi; Honda, Takashi; Fukuhara, Hideo; Hada, Kazumasa; Kimura, Makoto

    2006-08-01

    Ribonuclease P (RNase P) is a ribonucleoprotein complex involved in the processing of the 5'-leader sequence of precursor tRNA (pre-tRNA). Our earlier study revealed that RNase P RNA (pRNA) and five proteins (PhoPop5, PhoRpp38, PhoRpp21, PhoRpp29, and PhoRpp30) in the hyperthermophilic archaeon Pyrococcus horikoshii OT3 reconstituted RNase P activity that exhibits enzymatic properties like those of the authentic enzyme. In present study, we investigated involvement of the individual proteins in RNase P activity. Two particles (R-3Ps), in which pRNA was mixed with three proteins, PhoPop5, PhoRpp30, and PhoRpp38 or PhoPop5, PhoRpp30, and PhoRpp21 showed a detectable RNase P activity, and five reconstituted particles (R-4Ps) composed of pRNA and four proteins exhibited RNase P activity, albeit at reduced level compared to that of the reconstituted particle (R-5P) composed of pRNA and five proteins. Time-course analysis of the RNase P activities of R-4Ps indicated that the R-4Ps lacking PhoPop5, PhoRpp21, or PhoRpp30 had virtually reduced activity, while omission of PhoRpp29 or PhoRpp38 had a slight effect on the activity. The results indicate that the proteins contribute to RNase P activity in order of PhoPop5 > PhoRpp30 > PhoRpp21 > PhoRpp29 > PhoRpp38. It was further found that R-4Ps showed a characteristic Mg2+ ion dependency approximately identical to that of R-5P. However, R-4Ps had optimum temperature of around at 55 degrees C which is lower than 70 degrees C for R-5P. Together, it is suggested that the P. horikoshii RNase P proteins are predominantly involved in optimization of the pRNA conformation, though they are individually dispensable for RNase P activity in vitro.

  15. Leczenie otępienia przy współistniejących schorzeniach internistycznych – wybrane zagadnienia

    Directory of Open Access Journals (Sweden)

    Alicja Klich-Rączka

    2012-12-01

    Full Text Available Celem poniższej pracy było przedstawienie dylematów związanych ze stosowaniem leków poprawiających funkcje poznawcze przy obecności innych schorzeń u ludzi starszych. Ze względu na powszechną w starości polipatologię otępienie, będące jednym z najistotniejszych problemów medycznych w tym okresie życia, rzadko występuje jako pojedyncze schorzenie – zwykle współistnieje z innymi chorobami. Leczenie otępienia jest zwykle połączone z terapią innych jednostek chorobowych, co wiąże się ze zwiększonym ryzykiem interakcji lekowych oraz działań niepożądanych. Dodatkowo ryzyko tych działań wzrasta z powodu zmian w farmakokinetyce wynikających z gorszej dystrybucji leków w organizmie oraz pogarszającej się z wiekiem wydolności wielonarządowej, czego konsekwencją może być upośledzony metabolizm i wydalanie leków. Spośród stosowanych w leczeniu otępienia inhibitorów acetylocholinesterazy interakcje najczęściej dotyczą donepezilu, co spowodowane jest jego metabolizmem w wątrobie przy udziale cytochromu P450, który równocześnie uczestniczy w metabolizmie wielu innych leków wykorzystywanych w terapii różnych schorzeń wieku starczego. Przeciwwskazaniami do stosowania inhibitorów acetylocholinesterazy są przede wszystkim: ciężka niewydolność wątroby, zespół chorego węzła zatokowego, zaburzenia rytmu i przewodnictwa, czynna choroba wrzodowa żołądka lub dwunastnicy, choroby powodujące utrudnienie odpływu moczu, napady drgawkowe, astma oskrzelowa/przewlekła obturacyjna choroba płuc. Działania niepożądane leków występują u kilku do kilkudziesięciu procent pacjentów, a u części z nich stanowią przeciwwskazania do kontynuowania terapii. Problem interakcji lekowych i działań niepożądanych jest często marginalizowany w leczeniu starszych pacjentów z otępieniem.

  16. Návrh systému regulace vrtule stálých otáček

    OpenAIRE

    Líška, Lukáš

    2014-01-01

    Diplomová práca sa zaoberá problematikou návrhu elektrickej regulácie vrtule konštantných otáčok. Cieľom práce je ukázať postup návrhu regulátora na príklade vrtule DMP-3 pracujúcej s motorom Rotax 912 ULS, využitím vedomostí z mechaniky letu, elektrotechniky a automatizácie. V rámci práce bude poukázané na problematiku riadenia uhla nastavenia vrtule za použitia elektricky riadeného lineárneho aktuátora. Záver práce tvorí porovnanie výhod vrtule konštantných otáčok DMP-3 uvážením jej použiti...

  17. Overexpression, purification, crystallization and preliminary crystallographic studies of a hyperthermophilic adenylosuccinate synthetase from Pyrococcus horikoshii OT3

    International Nuclear Information System (INIS)

    Wang, Xiaoying; Akasaka, Ryogo; Takemoto, Chie; Morita, Satoshi; Yamaguchi, Machiko; Terada, Takaho; Shirozu, Mikako; Yokoyama, Shigeyuki; Chen, Shilin; Si, Shuyi; Xie, Yong

    2011-01-01

    A hyperthermophilic adenylosuccinate synthetase from P. horikoshii OT3, which is 90–120 amino acids shorter than those from the vast majority of organisms, was expressed, purified and crystallized and X-ray diffraction data were collected to 2.5 Å resolution. Adenylosuccinate synthetase (AdSS) is a ubiquitous enzyme that catalyzes the first committed step in the conversion of inosine monophosphate (IMP) to adenosine monophosphate (AMP) in the purine-biosynthetic pathway. Although AdSS from the vast majority of organisms is 430–457 amino acids in length, AdSS sequences isolated from thermophilic archaea are 90–120 amino acids shorter. In this study, crystallographic studies of a short AdSS sequence from Pyrococcus horikoshii OT3 (PhAdSS) were performed in order to reveal the unusual structure of AdSS from thermophilic archaea. Crystals of PhAdSS were obtained by the microbatch-under-oil method and X-ray diffraction data were collected to 2.50 Å resolution. The crystal belonged to the trigonal space group P3 2 12, with unit-cell parameters a = b = 57.2, c = 107.9 Å. There was one molecule per asymmetric unit, giving a Matthews coefficient of 2.17 Å 3 Da −1 and an approximate solvent content of 43%. In contrast, the results of native polyacrylamide gel electrophoresis and analytical ultracentrifugation showed that the recombinant PhAdSS formed a dimer in solution

  18. Caracterización de la comunidad de macroinvertebrados de la Quebrada Paloblanco de la Cuenca del Río Otún (Risaralda, Colombia)

    OpenAIRE

    Eleonora Bernal Pinilla; Duberney García García; Miguel Adriano Novoa Bravo; Atticus Pinzón Rodríguez

    2006-01-01

    Se realizó un estudio de las comunidades de macroinvertebrados presentes en la quebrada Paloblanco, ubicada en la cuenca del río Otún (Risaralda, Colombia). Los puntos de muestreo seleccionados corresponden a la cabecera y la zona cercana a la desembocadura en el río Otún, ambos con características geomorfológicas de corrientes de primer orden. En cada punto se colectaron los macroinvertebrados de las unidades funcionales hojarasca, epiliton, musgo y grava, junto con una muestra de deriva y f...

  19. Conservation of Repeats at the Mammalian KCNQ1OT1-CDKN1C Region Suggests a Role in Genomic Imprinting

    Directory of Open Access Journals (Sweden)

    Marcos De Donato

    2017-06-01

    Full Text Available KCNQ1OT1 is located in the region with the highest number of genes showing genomic imprinting, but the mechanisms controlling the genes under its influence have not been fully elucidated. Therefore, we conducted a comparative analysis of the KCNQ1/KCNQ1OT1-CDKN1C region to study its conservation across the best assembled eutherian mammalian genomes sequenced to date and analyzed potential elements that may be implicated in the control of genomic imprinting in this region. The genomic features in these regions from human, mouse, cattle, and dog show a higher number of genes and CpG islands (detected using cpgplot from EMBOSS, but lower number of repetitive elements (including short interspersed nuclear elements and long interspersed nuclear elements, compared with their whole chromosomes (detected by RepeatMasker. The KCNQ1OT1-CDKN1C region contains the highest number of conserved noncoding sequences (CNS among mammals, where we found 16 regions containing about 38 different highly conserved repetitive elements (using mVista, such as LINE1 elements: L1M4, L1MB7, HAL1, L1M4a, L1Med, and an LTR element: MLT1H. From these elements, we found 74 CNS showing high sequence identity (>70% between human, cattle, and mouse, from which we identified 13 motifs (using Multiple Em for Motif Elicitation/Motif Alignment and Search Tool with a significant probability of occurrence, 3 of which were the most frequent and were used to find transcription factor–binding sites. We detected several transcription factors (using JASPAR suite from the families SOX, FOX, and GATA. A phylogenetic analysis of these CNS from human, marmoset, mouse, rat, cattle, dog, horse, and elephant shows branches with high levels of support and very similar phylogenetic relationships among these groups, confirming previous reports. Our results suggest that functional DNA elements identified by comparative genomics in a region densely populated with imprinted mammalian genes may be

  20. Pressure effects on enzyme reactions in mainly organic media: alpha-chymotrypsin in reversed micelles of Aerosol OT in octane.

    Science.gov (United States)

    Mozhaev, V V; Bec, N; Balny, C

    1994-08-01

    Biocatalytic transformations in reversed micelles formed by anionic surfactant Aerosol OT in octane have been studied at high pressures by an example of alpha-chymotrypsin-catalyzed hydrolysis of N-carbobenzoxy-L-tyrosine p-nitrophenyl ester and N-succinyl-L-phenylalanine p-nitroanilide. For the first time it has been found that the enzyme retains high activity in these water-in-oil microemulsions up to a pressure of 2 kbar. The value of the activation volume (delta V*) for the enzyme reactions shows a dependence on the water content in the system. When the size of the micellar aqueous inner cavity (as evaluated at 1 atm) approaches the molecular size of alpha-chymotrypsin, delta V* becomes significantly different from the value in aqueous solution and in the micelles with a larger size. Possibilities of regulating the enzyme activity by pressure in systems with a low content of water are discussed.

  1. A genome-wide association study of bipolar disorder with comorbid eating disorder replicates the SOX2-OT region.

    Science.gov (United States)

    Liu, Xiaohua; Kelsoe, John R; Greenwood, Tiffany A

    2016-01-01

    Bipolar disorder is a heterogeneous mood disorder associated with several important clinical comorbidities, such as eating disorders. This clinical heterogeneity complicates the identification of genetic variants contributing to bipolar susceptibility. Here we investigate comorbidity of eating disorders as a subphenotype of bipolar disorder to identify genetic variation that is common and unique to both disorders. We performed a genome-wide association analysis contrasting 184 bipolar subjects with eating disorder comorbidity against both 1370 controls and 2006 subjects with bipolar disorder only from the Bipolar Genome Study (BiGS). The most significant genome-wide finding was observed bipolar with comorbid eating disorder vs. controls within SOX2-OT (p=8.9×10(-8) for rs4854912) with a secondary peak in the adjacent FXR1 gene (p=1.2×10(-6) for rs1805576) on chromosome 3q26.33. This region was also the most prominent finding in the case-only analysis (p=3.5×10(-7) and 4.3×10(-6), respectively). Several regions of interest containing genes involved in neurodevelopment and neuroprotection processes were also identified. While our primary finding did not quite reach genome-wide significance, likely due to the relatively limited sample size, these results can be viewed as a replication of a recent study of eating disorders in a large cohort. These findings replicate the prior association of SOX2-OT with eating disorders and broadly support the involvement of neurodevelopmental/neuroprotective mechanisms in the pathophysiology of both disorders. They further suggest that different clinical manifestations of bipolar disorder may reflect differential genetic contributions and argue for the utility of clinical subphenotypes in identifying additional molecular pathways leading to illness. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Kas ülikoolis õppimine on õige aeg lapse sünnitamiseks? / Ilona Opaal, Liis-Erliken Vinne, Tõnu Ots ... [jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad TLÜ anglistikaüliõpilane Ilona Opaal, TLÜ bioloogiaüliõpilane Liis-Erliken Vimme, psühholoog Tõnu Ots, filosoof Valdar Parve, Soome Instituudi direktor Jaana Vasama, psühholoog Tiia Lister, Treffneri Gümnaasiumi usu- ja filosoofiaõpetaja Toomas Jürgenstein

  3. Databáze a generování testovacích otázek

    OpenAIRE

    Rejko, Peter

    2008-01-01

    Cílem bakalářské práce je vytvoření databáze testovacích otázek a jejich generování. Je rozdělená na teoretickou a praktickou část. V teoretické jsou popsané nástroje se zaměřením na tvorbu databází jazyku HTML, PHP a databázový server MySQL. Praktická část obsahuje vytvořenou aplikaci a zpracování. Jazyk PHP podporuje programování na základě modulárního paradigmatu - to znamená, že každý vytvořený modul má svoji úlohu. Aplikace obsahuje modul zabezpečující přihlášení a výběr dalšího modulu n...

  4. Crystallization and preliminary X-ray analysis of PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins

    International Nuclear Information System (INIS)

    Shirokane, Michio; Sawano, Yoriko; Miyazono, Ken-ichi; Nagata, Koji; Tanokura, Masaru

    2007-01-01

    PH1010, a DUF54-family protein from the hyperthermophilic archaeon P. horikoshii OT3, was crystallized and X-ray diffraction data were collected to 1.90 Å resolution. PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins, was expressed, purified and crystallized. Crystallization was performed by the sitting-drop vapour-diffusion method using PEG 3350 as the precipitant. The crystal diffracted X-rays to 1.90 Å resolution using a synchrotron-radiation source. The space group of the crystal was determined to be P2 1 2 1 2 1 , with unit-cell parameters a = 46.9, b = 49.5, c = 132.7 Å. The crystal contained two PH1010 molecules in the asymmetric unit (V M = 2.4 Å 3 Da −1 ) and had a solvent content of 48%

  5. Crystallization and preliminary X-ray analysis of PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins

    Energy Technology Data Exchange (ETDEWEB)

    Shirokane, Michio; Sawano, Yoriko; Miyazono, Ken-ichi; Nagata, Koji; Tanokura, Masaru, E-mail: amtanok@mail.ecc.u-tokyo.ac.jp [Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657 (Japan)

    2007-06-01

    PH1010, a DUF54-family protein from the hyperthermophilic archaeon P. horikoshii OT3, was crystallized and X-ray diffraction data were collected to 1.90 Å resolution. PH1010 from Pyrococcus horikoshii OT3, a member of the archaeal DUF54 family of proteins, was expressed, purified and crystallized. Crystallization was performed by the sitting-drop vapour-diffusion method using PEG 3350 as the precipitant. The crystal diffracted X-rays to 1.90 Å resolution using a synchrotron-radiation source. The space group of the crystal was determined to be P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 46.9, b = 49.5, c = 132.7 Å. The crystal contained two PH1010 molecules in the asymmetric unit (V{sub M} = 2.4 Å{sup 3} Da{sup −1}) and had a solvent content of 48%.

  6. DNA methylation patterns of imprinting centers for H19, SNRPN, and KCNQ1OT1 in single-cell clones of human amniotic fluid mesenchymal stem cell

    Directory of Open Access Journals (Sweden)

    Hsiu-Huei Peng

    2012-09-01

    Conclusion: In conclusion, human amniotic fluid mesenchymal stem cells contain a unique epigenetic signature during in vitro cell culture. H19 and KCNQ1OT1 possessed a substantial degree of hypermethylation status, and variable DNA methylation patterns of SNRPN was observed during in vitro cell culture of human amniotic fluid mesenchymal stem cells. Our results urge further understanding of epigenetic status of human amniotic fluid mesenchymal stem cells before it is applied in cell replacement therapy.

  7. Geología de la zona de influencia de la falla otú en el distrito minero segovia-remedios

    Directory of Open Access Journals (Sweden)

    MILTON ÁLVAREZ GALINDEZ

    2007-01-01

    Full Text Available Se presenta la caracterización geológica y estructural de la zona de influencia de la falla Otú en jurisdicción del distrito minero Segovia-Remedios. Además, se proponen controles mecánicos para las mineralizaciones auríferas, que si bien son compatibles, en parte, con un modelo de depósitos de oro orogénico, dejan abiertas otras posibles interpretaciones

  8. Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri.

    Directory of Open Access Journals (Sweden)

    Evelyne Derelle

    Full Text Available Large DNA viruses are ubiquitous, infecting diverse organisms ranging from algae to man, and have probably evolved from an ancient common ancestor. In aquatic environments, such algal viruses control blooms and shape the evolution of biodiversity in phytoplankton, but little is known about their biological functions. We show that Ostreococcus tauri, the smallest known marine photosynthetic eukaryote, whose genome is completely characterized, is a host for large DNA viruses, and present an analysis of the life-cycle and 186,234 bp long linear genome of OtV5. OtV5 is a lytic phycodnavirus which unexpectedly does not degrade its host chromosomes before the host cell bursts. Analysis of its complete genome sequence confirmed that it lacks expected site-specific endonucleases, and revealed the presence of 16 genes whose predicted functions are novel to this group of viruses. OtV5 carries at least one predicted gene whose protein closely resembles its host counterpart and several other host-like sequences, suggesting that horizontal gene transfers between host and viral genomes may occur frequently on an evolutionary scale. Fifty seven percent of the 268 predicted proteins present no similarities with any known protein in Genbank, underlining the wealth of undiscovered biological diversity present in oceanic viruses, which are estimated to harbour 200Mt of carbon.

  9. Matrjoshki ot kutjur

    Index Scriptorium Estoniae

    2008-01-01

    Vene moeajakirja Vogue kümnendaks juubeliks joonistasid tuntud moekunstnikud kogu maailmast matrjoshkade eskiise. Eskiiside järgi maalisid vene meistrid poolemeetrised nukud. Nii sai ajakiri kingituseks Yves Saint Laurent'i, Versace, Prada, Dolce&Gabbana, Oscar de la Renta, Judashkini, Simatshovi ja paljude teiste matrjoshkad

  10. Contribution to study of Dancoff effect in cylindrical systems; Prilog proucavanju Dancoffovog efekta u sistemima sa cilindricnom geometrijom

    Energy Technology Data Exchange (ETDEWEB)

    Remsak, S [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Yugoslavia)

    1969-09-15

    This paper deals with the affect od spatial interference between fuel elements and its influence on the resonance integral. General relation for correction of shielding dependent on the first collision portability was derived. Usual assumption about totally black resonance absorber was not taken into account and spatial distribution of elements was random. Shielding effect for two rods and self-shielding effect of tube was studied in detail. Analysis of standard Dancoff problem shows that the shielding correction function is dependent on all resonance parameters, temperature, size of rods and their mutual distance and properties of the moderator. Proposed method is based on the assumption of flat fluxes which enable analytical determination of first collision probability. Influence of interference scattering was taken into account afterwards and was not treated directly. System of balance equations was solved by applying IR approximation. In order to enable easier numerical calculation of shielding correction significant simplification of obtained results was done by applying P-L approximation of Bonaloumi. Obtained numerical results show good agreement with values obtained by applying Hellstrand empirical relation for resonance integral. A simple procedure is proposed for redefining some parameters and Asiu equations which enable more precise determination of transparency coefficient of tube element.

  11. Purification, crystallization and preliminary X-ray crystallographic analysis of the archaeal phosphoglycerate mutase PH0037 from Pyrococcus horikoshii OT3

    Energy Technology Data Exchange (ETDEWEB)

    Lokanath, Neratur K.; Kunishima, Naoki, E-mail: kunisima@spring8.or.jp [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan)

    2006-08-01

    The archaeal phosphoglycerate mutase PH0037 from P. horikoshii OT3 has been crystallized in space group R32, with unit-cell parameters a = 155.62, c = 230.35 Å. A 2.2 Å resolution data was collected at SPring-8 beamline BL26B1. Phosphoglycerate mutases catalyze the interconversion of 2-phosphoglycerate and 3-phosphoglycerate in glycolysis and gluconeogenesis pathways. The archaeal phosphoglycerate mutase PH0037 from Pyrococcus horikoshii OT3 has been overexpressed in Escherichia coli and purified. Crystals were obtained using the oil-microbatch method at 291 K. A native data set extending to a resolution of 2.2 Å has been collected and processed in space group R32. Assuming the presence of a dimer in the asymmetric unit, the V{sub M} value is calculated to be 3.0 Å{sup 3} Da{sup −1}, consistent with the dynamic light-scattering experiment result, which shows a dimeric state of the protein in solution. Molecular-replacement trials using the crystal structure of Bacilllus stearothermophilus phosphoglycerate mutase as a search model did not provide a satisfactory solution, indicating substantially different structures of these two phophoglycerate mutases.

  12. Purification, crystallization and preliminary X-ray diffraction studies of a putative UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

    Energy Technology Data Exchange (ETDEWEB)

    Lokanath, Neratur K.; Pampa, Kudigana J.; Kamiya, Toshimi; Kunishima, Naoki, E-mail: kunisima@spring8.or.jp [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan)

    2007-05-01

    A putative UDP-N-acetyl-d-mannosamine dehydrogenase from P. horikoshii OT3 has been crystallized in space group P2{sub 1}, with unit-cell parameters a = 80.28, b = 69.24, c = 83.10 Å, β = 114.4°. X-ray diffraction data have been collected to 1.80 Å resolution. A putative UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3, an essential enzyme for polysaccharide biosynthesis, has been overexpressed in Escherichia coli and purified. Crystals were obtained using the oil-microbatch method at 291 K. A native data set extending to 1.8 Å resolution has been collected and processed in space group P2{sub 1}. Assuming the presence of a dimer in the asymmetric unit, the V{sub M} value is calculated to be 2.3 Å{sup 3} Da{sup −1}, which is consistent with the result of a dynamic light-scattering experiment that shows a dimeric state of the protein in solution.

  13. Transcriptional analysis and molecular dynamics simulations reveal the mechanism of toxic metals removal and efflux pumps in Lysinibacillus sphaericus OT4b.31

    KAUST Repository

    Shaw, Dario Rangel

    2017-11-23

    Lysinibacillus sphaericus strain OT4b.31 is a bacterium widely applied in bioremediation processes of hydrocarbon and metal polluted environments. In this study, we identified the molecular mechanism underlying the Pb2+ and Cr6+ resistance. Metal uptake and temporal transcription patterns of metal resistance operons were evaluated using reverse-transcribed quantitative PCR amplification. The function of the resistance determinants was studied applying docking and in silico mutagenesis methods. The results revealed that the adaptation of Lysinibacillus sphaericus OT4b.31 to elevated levels of lead and chromium involves the pbr and chr operons which comprise a transcriptional regulatory component (pbrR and chrB) and efflux ATPases (pbrA and chrA) to expel ions from the cytoplasm. Expression of metal resistance genes was constitutive and specifically inducible to the exposure of Pb2+ and Cr6+. The simultaneous presence of cations didn\\'t affect the bioaccumulation of metals, evidencing the multimetal resistance of L. sphaericus. Docking analysis revealed the key metal-protein interactions and the conformational changes after metal or ATP binding. Results showed that residues with aromatic rings or imidazole in the catalytic domain are crucial for metal binding and achievement of the function. To our knowledge, this is the first report of a specific mechanism for lead and chromium resistance in Lysinibacillus genus. From the findings of this study, it is possible to suggest the bacterium as a suitable candidate for rapid toxic metals bioremediation processes.

  14. A Otávia do Pseudo-Sêneca: tradução, estudo introdutório e notas

    OpenAIRE

    Fernanda Vieira Gôzo

    2016-01-01

    Esta pesquisa de mestrado objetivou o estudo da peça latina Otávia do Pseudo-Sêneca, que inclui uma tradução para o português, acompanhada de notas e de um estudo introdutório. Este trabalho centrou-se em apontar o que se têm discutido entre os estudiosos de literatura clássica em relação à peça. Foi pertinente para esse expediente uma análise do gênero praetexta, do qual faz parte esta peça, considerando as divergências entre praetexta republicana e imperial, bem como a observação de como a ...

  15. Caracterización de la comunidad de macroinvertebrados de la Quebrada Paloblanco de la Cuenca del Río Otún (Risaralda, Colombia

    Directory of Open Access Journals (Sweden)

    Eleonora Bernal Pinilla

    2006-07-01

    Full Text Available Se realizó un estudio de las comunidades de macroinvertebrados presentes en la quebrada Paloblanco, ubicada en la cuenca del río Otún (Risaralda, Colombia. Los puntos de muestreo seleccionados corresponden a la cabecera y la zona cercana a la desembocadura en el río Otún, ambos con características geomorfológicas de corrientes de primer orden. En cada punto se colectaron los macroinvertebrados de las unidades funcionales hojarasca, epiliton, musgo y grava, junto con una muestra de deriva y fauna general (sin discriminar unidad funcional. Se encontraron 42 familias de Insecta, además de Acari, Annelida, Crustacea e Hirudinea. Igualmente se encontraron familias de presencia exclusiva en cada punto, mostrando diferencias en la composición de las comunidades. Los índices ecológicos empleados mostraron una mayor diversidad en punto bajo y diferencias entre algunas de las unidades funcionales, relacionados con el medio y los hábitos presentes. Para el análisis se tuvieron en cuenta los conceptos de continuo y zonación de los ríos. A pesar de tener condiciones de primer orden, existen variaciones a pequeña escala entre los puntos de muestreo, que están relacionadas con la intervención antrópica en la zona aledaña a punto bajo.

  16. Evaluación de la diversidad de bacterias degradadoras de hidrocarburos aisladas de suelos de las cuencas de los ríos Otún y La Vieja / Evaluation of hydrocarbon degrading bacteria diversity isolated from soils of Otún and La Vieja river basins

    OpenAIRE

    Yanine Suárez, Habib Fernando

    2010-01-01

    Se evaluó el efecto del uso del suelo, sobre la densidad y diversidad de bacterias degradadoras de hidrocarburos (HC). Se seleccionaron los usos: bosque, pastizal y cafetal en la cuenca del río La Vieja (Valle del Cauca y Quindío), y bosque, cebollar y plantación forestal en la cuenca del río Otún (Risaralda) y se realizaron dos eventos de muestreo. La densidad se evaluó mediante la técnica de NMP en medio Bushnell-Hass, suplementado con diesel y usando XTT como indicador de actividad. Las ba...

  17. Resenha de 1976: Movimento Black Rio, de Luiz Felipe de Lima Peixoto e Zé Otávio Sabadelhe (Rio de Janeiro: José Olympio, 2016

    Directory of Open Access Journals (Sweden)

    Carlos Palombini

    2017-08-01

    Full Text Available Lançado em 10 de novembro de 2016, o livro 1976: Movimento Black Rio, dos jornalistas Luiz Felipe de Lima Peixoto e Zé Otávio Sabadelhe, celebra os quarenta anos da manchete de Lena Frias, Black Rio: o orgulho (importado de ser negro no Brasil, publicada em 17 de julho de 1976 no Caderno B do Jornal do Brasil. Em 28 reportagens, os autores recorrem a entrevistas e material previamente publicado para contar a história da cultura de bailes que, alimentados por soul, funk e disco afro-norte-americanos, espalharam-se pela Zona Norte carioca nos anos 1970, bem como a história do conjunto das apropriações desses gêneros por Tim Maia, Toni Tornado, Hyldon, Carlos Dafé, Cassiano, Gerson King Combo, Dom Salvador e Abolição, União Black, e Banda Black Rio. O livro tenciona constituir “uma contribuição à construção discursiva de uma memória social positiva da população negra brasileira” e oferece elementos para um trabalho necessário de revisão historiográfica que transcende o âmbito do tema tratado, apesar de erros fatuais que poderiam ter sido corrigidos por cruzamento de dados.

  18. Reversal of hepatorenal syndrome type 1 with terlipressin plus albumin vs. placebo plus albumin in a pooled analysis of the OT-0401 and REVERSE randomised clinical studies.

    Science.gov (United States)

    Sanyal, A J; Boyer, T D; Frederick, R T; Wong, F; Rossaro, L; Araya, V; Vargas, H E; Reddy, K R; Pappas, S C; Teuber, P; Escalante, S; Jamil, K

    2017-06-01

    The goal of hepatorenal syndrome type 1 (HRS-1) treatment is to improve renal function. Terlipressin, a synthetic vasopressin analogue, is a systemic vasoconstrictor used for the treatment of HRS-1, where it is available. To compare the efficacy of terlipressin plus albumin vs. placebo plus albumin in patients with HRS-1. Pooled patient-level data from two large phase 3, randomised, placebo-controlled studies were analysed for HRS reversal [serum creatinine (SCr) value ≤133 μmol/L], 90-day survival, need for renal replacement therapy and predictors of HRS reversal. Patients received intravenous terlipressin 1-2 mg every 6 hours plus albumin or placebo plus albumin up to 14 days. The pooled analysis comprised 308 patients (terlipressin: n = 153; placebo: n = 155). HRS reversal was significantly more frequent with terlipressin vs. placebo (27% vs. 14%; P = 0.004). Terlipressin was associated with a more significant improvement in renal function from baseline until end of treatment, with a mean between-group difference in SCr concentration of -53.0 μmol/L (P albumin resulted in a significantly higher rate of HRS reversal vs. albumin alone in patients with HRS-1. Terlipressin treatment is associated with improved renal function. (ClinicalTrials.gov identifier: OT-0401, NCT00089570; REVERSE, NCT01143246). © 2017 The Authors. Alimentary Pharmacology and Therapeutics published by John Wiley & Sons Ltd.

  19. Hıyarda (Cucumis sativus L. yabancı ot çıkış zamanın tahminine yönelik araştırmalar

    Directory of Open Access Journals (Sweden)

    Nihat Tursun

    2015-01-01

    Full Text Available İstatistiki modellerin geliştirilmesi için hıyar bitkisinde on bir önemli yabancı otun çıkış zamanın belirlenmesinde modellemeler yapılmıştır. Hıyar deneme arazisinde bulunan önemli yabancı otlar çıkış zamanlarına göre gruplara ayrılmıştır. Bu yabancı otlardan; Amaranthus retroflexus, Chenopodium album, Heliotropium europaeum, Polygonum aviculare ve Solanum nigrum erken, Convolvulus arvensis, Cyperus rotundus, Cynodon dactylon, Portulaca oleracea ve Sorghum halepense bütün vejetasyon boyunca ve Tribulus terrestris ise geç çimlenen yabancı ot türü olarak belirlenmiştir. Farklı doğrusal olmayan büyüme eğrileri (Chapman-Richard, Weibull, logistic, Gompertz ve cubic spline farklı yabancı ot türleri ve yıllar için çıkış yüzdeleri verileri esas alınarak uyarlanmıştır. Cubic splin model birçok yabancı ot türü için en iyi model olarak saptanmıştır.

  20. Identification of a novel amino acid racemase from a hyperthermophilic archaeon Pyrococcus horikoshii OT-3 induced by D-amino acids.

    Science.gov (United States)

    Kawakami, Ryushi; Ohmori, Taketo; Sakuraba, Haruhiko; Ohshima, Toshihisa

    2015-08-01

    To date, there have been few reports analyzing the amino acid requirement for growth of hyperthermophilic archaea. We here found that the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 requires Thr, Leu, Val, Phe, Tyr, Trp, His and Arg in the medium for growth, and shows slow growth in medium lacking Met or Ile. This largely corresponds to the presence, or absence, of genes related to amino acid biosynthesis in its genome, though there are exceptions. The amino acid requirements were dramatically lost by addition of D-isomers of Met, Leu, Val, allo-Ile, Phe, Tyr, Trp and Arg. Tracer analysis using (14)C-labeled D-Trp showed that D-Trp in the medium was used as a protein component in the cells, suggesting the presence of D-amino acid metabolic enzymes. Pyridoxal 5'-phosphate (PLP)-dependent racemase activity toward Met, Leu and Phe was detected in crude extract of P. horikoshii and was enhanced in cells grown in the medium supplemented with D-amino acids, especially D-allo-Ile. The gene encoding the racemase was narrowed down to one open reading frame on the basis of enzyme purification from P. horikoshii cells, and the recombinant enzyme exhibited PLP-dependent racemase activity toward several amino acids, including Met, Leu and Phe, but not Pro, Asp or Glu. This is the first report showing the presence in a hyperthermophilic archaeon of a PLP-dependent amino acid racemase with broad substrate specificity that is likely responsible for utilization of D-amino acids for growth.

  1. Crystallization and preliminary X-ray crystallographic studies of the biotin carboxyl carrier protein and biotin protein ligase complex from Pyrococcus horikoshii OT3

    International Nuclear Information System (INIS)

    Bagautdinov, Bagautdin; Matsuura, Yoshinori; Bagautdinova, Svetlana; Kunishima, Naoki

    2007-01-01

    A truncated form of biotin carboxyl carrier protein containing the C-terminal half fragment (BCCPΔN76) and the biotin protein ligase (BPL) with the mutation R48A (BPL*) or the double mutation R48A K111A (BPL**) were successfully cocrystallized in the presence of ATP and biotin. The BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals belong to space group P2 1 and diffract X-rays to 2.7 and 2.0 Å resolution, respectively. Biotin protein ligase (BPL) catalyses the biotinylation of the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase. To elucidate the exact details of the protein–protein interactions in the biotinylation function, the C-terminal half fragment of BCCP (BCCPΔN76), the R48A mutant of BPL (BPL*) and the R48A K111A double mutant of BPL (BPL**), all of which are from Pyrococcus horikoshii OT3, have been expressed, purified and successfully cocrystallized. Cocrystals of the BPL*–BCCPΔN76 and BPL**–BCCPΔN76 complexes as well as crystals of BPL*, BPL** and BCCPΔN76 were obtained by the oil-microbatch method using PEG 20 000 as a precipitant at 295 K. Complete X-ray diffraction data sets for BPL*–BCCPΔN76 and BPL**–BCCPΔN76 crystals were collected at 100 K to 2.7 and 2.0 Å resolution, respectively, using synchrotron radiation. They belong to the monoclinic space group P2 1 , with similar unit-cell parameters a = 69.85, b = 63.12, c = 75.64 Å, β = 95.9°. Assuming two subunits of the complex per asymmetric unit gives a V M value of 2.45 Å 3 Da −1 and a solvent content of 50%

  2. Samozashtshita ot oruzhija / Ljubov Semjonova

    Index Scriptorium Estoniae

    Semjonova, Ljubov

    2002-01-01

    Andrei Dikarev, Föderatsiooni Aikido president Eestis, leiab, et Eestis on vaja rohkem teadvustada inimestele, mida tähendab isiklik julgeolek. Vt. samas interv. Politseiameti korrakaitseinspektori Vambo Olbergiga eraisikute valduses olevate relvade teemal

  3. Dokazatelstvo ot obratnogo / Lev Livshits

    Index Scriptorium Estoniae

    Лившиц, Лев, 1924-2013

    2008-01-01

    UNESCO maailmapärandi nimekirja kuuluva Tallinna vanalinna kaitsetsooni loomisest ja kõrghoonete ehitamisest vanalinna läheduses. UNESCO komitee nõuab vanalinna puhvertsooni loomise kava ja ülevaadet Tallinna kõrghoonete teemaplaneeringust

  4. 59 Cyg and OT Gem

    Indian Academy of Sciences (India)

    2009-07-23

    Jul 23, 2009 ... of the circumstellar disk using the Hα line and also ... the time interval 1978–1987 and saw the V /R variabil- ..... Time series of 59 Cyg Hα line observed in July 2009; (Spectra are offset and labelled with the observation date,.

  5. Zastosowanie jakościowej analizy profilu wykonania skali ACE-III w diagnostyce różnicowej chorób otępiennych

    Directory of Open Access Journals (Sweden)

    Emilia J. Sitek

    2017-03-01

    Full Text Available Skala Addenbrooke’s Cognitive Examination III (ACE-III jest poszerzonym narzędziem przesiewowej oceny funkcji poznawczych, użytecznym we wczesnym wykrywaniu zaburzeń poznawczych, wstępnej diagnostyce różnicowej zespołów otępiennych oraz monitorowaniu postępu choroby. ACE-III ocenia uwagę i orientację, pamięć, fluencję słowną, funkcje językowe i wzrokowo-przestrzenne. Skala może być używana przez lekarzy i psychologów, zarówno jako narzędzie przesiewowe, jak i jako wstęp do kompleksowej oceny neuropsychologicznej. ACE-III zawiera również krótsze narzędzie, Mini-ACE, które w razie potrzeby może być stosowane niezależnie. W niniejszej pracy ACE-III porównano z innymi najbardziej popularnymi skalami przesiewowej oceny funkcji poznawczych: Mini-Mental State Examination (MMSE oraz Montrealską Skalą Oceny Funkcji Poznawczych (Montreal Cognitive Assessment, MoCA. Następnie omówiono przydatność kliniczną analizy profilu wykonania ACE-III w  diagnostyce różnicowej wybranych chorób neurozwyrodnieniowych. Zaprezentowano profile wykonania ACE-III typowe dla choroby Alzheimera (zarówno o wczesnym, jak i o późnym początku, zwyrodnienia czołowo-skroniowego, choroby Parkinsona, atypowych zespołów parkinsonowskich oraz otępienia naczyniopochodnego. Spośród atypowych wariantów choroby Alzheimera uwzględniono zanik korowy tylny, wariant logopeniczny afazji pierwotnej postępującej i wariant czołowy. Spośród podstawowych wariantów zwyrodnienia czołowo-skroniowego przedstawiono wariant behawioralny otępienia czołowo- -skroniowego oraz niepłynny i semantyczny wariant afazji pierwotnej postępującej. Wreszcie spośród zespołów parkinsonizm plus omówiono otępienie z ciałami Lewy’ego, zanik wieloukładowy, postępujące porażenie ponadjądrowe i zwyrodnienie korowo-podstawne.

  6. Muusika : Hortus Musicus Moskvas. Eesti Rahvusmeeskoor Toulouse'is. Joaquín Rodrigo 100. Georg Ots kuuel plaadil. "Kiriku laulu- ja palveraamat" ئ 10. "Vikerraadio" heategevuskontsert. Artur Kapi ühingu esimees on Andres Uibo / Vello Mäeots

    Index Scriptorium Estoniae

    Mäeots, Vello, 1940-2015

    2001-01-01

    20. XI esines Hortus Musicus Moskvas Eesti saatkonnas. Eesti Rahvusmeeskoor kandis 15.XI Toulouse'is koos Toulouse'i Rahvusliku Linnaorkestriga ette Jean Sibeliuse "Kullervo". 22.XI tähistatakse hispaania helilooja Joaquín Rodrigo 100. sünniaastapäeva. Estonia teatri Valges saalis esitleti kogumik-CD-d "Georg Ots ئ Anthology". "Kiriku laulu- ja palveraamat" sai 30.XI 10. aastaseks. 3.XII toimub Tallinnas Kaarli kirikus "Vikerraadio" heategevuskontsert "Aita alustada elu". 26.X asutati Suure-Jaanis Rahvusvaheline Artur Kapi Ühing, mille esimeheks valiti organist Andres Uibo

  7. Dinámica de construcción territorial en los asentamientos del río Otún en Pereira (1950- 2000: fenomenología a la territorialidad del sujeto habitante

    Directory of Open Access Journals (Sweden)

    Julio César Murillo García

    2016-06-01

    Full Text Available El presente artículo surge como resultado del análisis- interpretación a la dinámica territorial en los asentamientos informales ubicados sobre las márgenes del río Otún a su paso por la comuna Otún en la ciudad de Pereira, desde dos momentos nodales de su construcción: momento fundacional (1950 y momento de toma y apropiación de predios (2000. Como metodología se asume la fenomenología a la territorialidad cotidiana del habitante, explícitamente desde dos variables: contexto socioeconómico y vínculos territoriales. A partir de allí se consolidaron universos de análisis e interpretación sobre la territorialidad del sujeto que dan cuenta de fricciones y/o conflictos espaciales con respecto a la política pública territorial del municipio de Pereira, en medio de la ejecución de programas y proyectos de gestión y planificación territorial con un denotado carácter hegemónico. Con ello se despeja un panorama crítico reflexivo alrededor de la implementación de estas políticas y al desarrollo sostenible territorial.

  8. CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4+ T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice

    Directory of Open Access Journals (Sweden)

    Tomasz Maj

    2014-01-01

    Full Text Available Immune phenomena during the preimplantation period of pregnancy are poorly understood. The aim of our study was to assess the capacity for antigen presentation of splenic antigen-presenting cells (APCs derived from pregnant and pseudopregnant mice in in vitro conditions. Therefore, sorted CD11c+ dendritic cells and macrophages F4/80+ and CD11b+ presenting ovalbumin (OVA were cocultured with CD4+ T cells derived from OT-II mice’s (C57BL6/J-Tg(TcraTcrb1100Mjb/J spleen. After 132 hours of cell culture, proliferation of lymphocytes (ELISA-BrdU, activation of these cells (flow cytometry, cytokine profile (ELISA, and influence of costimulatory molecules blocking on these parameters were measured. We did not detect any differences in regulation of Th1/Th2 cytokine balance. CD86 seems to be the main costimulatory molecule involved in the proliferation response but CD80 is the main costimulatory molecule influencing cytokine secretion in pregnant mice. In conclusion, this study showed that CD80 and CD86 costimulatory molecules regulate OT-II CD4+ T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice. The implications of these changes still remain unclear.

  9. Erodabilidad y erosión hídrica potencial en un sector de la cuenca del rio Otún - Colombia

    Directory of Open Access Journals (Sweden)

    Madero Morales Edgar Enrique

    1996-12-01

    Full Text Available

    The present research seeks to determine the applicability of simple, rapid and economic methods tor comparing the soil erodability under twelve cultivation systems, and besides to record the features of rill erosion under ale crops in the watershed area of the Otún river. Here the denudation processes are common and affect a large portion of the area. The erodability tests considered (crumb, pinhole, manipulation, rain acceptance, soil loss, shear strenght are related to soil toss with reference to erodable material and the volume of surface flow. These do not seek to quantify the actual or potential soil loss of a place, but can help in the estimation of the variability of soil erodability with the content of surface gravel, the state soil moisture content and time. To predict the advance of rill and interril erosion in bare soil, Bergsma (1989 developed a semicuantitative system with this purpose, and what is related to the presence and frequency of six microtopography soil surface features after each rain and at the end of tillage: original clods, eroding clods, depressional areas, linear flow pattern of shallow channels and deeper rills, and coverage (vegetation, gravel, etc.; each feature has a length less than 25 cm. The erodability tests demonstrate their practical value with no more than three repetitions per unit of management. There was more soils (8/12 with low erodability. The evolution of microtopograhy soil surface features showed that corn, bean and grass increased depressional areas and shallow channels; the tendency in onion was similar but with a relatibility increase in deeper rills. Bean and grass crops were the less erosion hazard uses because they let a few loss of soil at the more inestable terrains. Contrary, corn and onion are not the most recomendable uses because they allowed the biggest advance of erosion in the most stable soils.

    Las pruebas de erodabilidad consideradas (terrón, agujero, manipulación o

  10. Investigación y práctica urbanística desde la Escuela de Arquitectura de Madrid : 20 años de actividad del Instituto Juan de Herrera (SPyOT, 1977-1997

    Directory of Open Access Journals (Sweden)

    Ramón López de Lucio

    1997-11-01

    For two decades now, research and urban practice at Escuela Técnica Superior de Arquitectura de Madrid has notably come apart from dominant planning ideology, in which "urban project" has been considered from a quite reductionist approach, so embedded in the paradigmatic tautology of "urban urbanism", as the only way of working and teaching. In 1977 a group of professors of what latter became the Departamento de Urbanística y Ordenación del Territorio de la E.T.S. de Arquitectura de Madrid decided to organize themselves as a working group with the objective of developing research projects and eventually professional work of particular interest in the fields of city and regional planning. Under the name of Seminario de Planeamiento y Ordenación del Territorio (SPyOT this group started a series of research projects focusing initially in Madrid -as central object of study and laboratory of new planning initiatives- and in the comprehensive plans of the main Spanish cities. After 20 years of uninterrupted activity the initial group has grown and consolidated, and its fields of activity have expanded. More than one hundred projects coordinated by two dozens of professors have been completed in which about 200 hundred students have cooperated. A permanent platform for research within the university has developed and an alternative for professional work for full-time professors has been created, following the guidelines of the University Reform Law (LRU. A considerable number of outstanding students have started careers in the planning field, both in the public and private sectors. After 20 years it can be said that the always difficult relationship between academia and the professional world, both for students and professors, has been facilitated by the existence of the SPyOT. Today the SPyOT has become the Sección de Urbanismo del Instituto Juan de Herrera. This publication includes, after some introductory remarks by the Directors of the Planning Department of the

  11. Modifications to the restriction method of Gentry and Casanas for otariid pups Modificaciones al método de restricción de Gentry y Casanas para crías de otáridos

    Directory of Open Access Journals (Sweden)

    Janitzio Égido-Villarreal

    2007-06-01

    Full Text Available To avoid risky and expensive chemical immobilization of otariid pups, physical restriction is a better option. For this reason we constructed a stretcher that permits wide liberty to interact with the pup and take a variety of samples in a safe, comfortable and easy way, for both the pup and the researcher.Para evitar el uso de la riesgosa y cara restricción química en crías de otáridos la mejor opción es la restricción física. Por lo anterior construimos una camilla que permite amplia libertad para la toma de diferentes tipos de muestras de manera segura, cómoda y fácil tanto para la cría como para el investigador.

  12. Patrones de relación entre información biológica e información física y socioeconómica : cuenca alta del Río Otún, Risaralda Colombia

    OpenAIRE

    Coronel Picón, Yulieth Rossio

    2009-01-01

    En este trabajo se realizó un análisis de información física, socioeconómica y biológica de la cuenca del río Otún. Se presenta la metodología utilizada para la identificación de patrones de relación entre la información física y socioeconómica de la cuenca y la presencia de algunos mamíferos identificados en esta zona, y los resultados obtenidos. La identificación de patrones se llevó a cabo mediante la aplicación de árboles de decisión, utilizando el algoritmo j-48 desarrollado en el entorn...

  13. Investigations of the 0.020-scale 88-OTS Integrated Space Shuttle Vehicle Jet-Plume Model in the NASA/Ames Research Center 11 by11-Foot Unitary Plan Wind Tunnel (IA80). Volume 1

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    The results are documented of jet plume effects wind tunnel test of the 0.020-scale 88-OTS launch configuration space shuttle vehicle model in the 11 x 11 foot leg of the NASA/Ames Research Center Unitary Plan Wind Tunnel. This test involved cold gas main propulsion system (MPS) and solid rocket motor (SRB) plume simulations at Mach numbers from 0.6 to 1.4. Integrated vehicle surface pressure distributions, elevon and rudder hinge moments, and wing and vertical tail root bending and torsional moments due to MPS and SRB plume interactions were determined. Nozzle power conditions were controlled per pretest nozzle calibrations. Model angle of attack was varied from -4 deg to +4 deg; model angle of sideslip was varied from -4 deg to +4 deg. Reynolds number was varied for certain test conditions and configurations, with the nominal freestream total pressure being 14.69 psia. Plotted force and pressure data are presented.

  14. Results of investigations conducted in the LaRC 4-foot unitary plan wind tunnel leg no. 1 using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA94A)

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    Aero-loads investigations were conducted on the updated configuration-5 space shuttle launch vehicle at Mach numbers 2.50, 3.50, and 4.50. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested, with two different forward orbiter-to-external-tank attach-strut configurations. The entire vehicle model 72-OTS was supported by means of a balance mounted in the orbiter through its base and suspended from an appropriate sting for the specific tunnel.

  15. Testimonios arqueológicos del Oriente Próximo reflejados en el Séfer–Masa`ot de Benjamín de Tudela (Siria-Palestina, Mesopotamia y Egipto

    Directory of Open Access Journals (Sweden)

    Magdalena Nom de Déu, José Ramón

    2005-04-01

    Full Text Available Benjamín de Tudela (en hebreo Biniamín ben rabbí Yonah mi- Tudela es, sin duda, un navarro universal. Judío de la aljama tudelana, se ignora la fecha de su nacimiento (acaso hacia 1130. Hijo de rabino y viajero infatigable, sólo sabemos de este personaje lo poco que de él se menciona en su famoso Libro de Viajes o Séfer-masa`ot, fruto de sus vivas experiencias —las más de las veces directas— exquisitamente plasmadas en su relación de viaje, redactadas en hebreo. Conocedor del romance navarro vernáculo de la época, sabía hebreo - su lengua de instrucción y cultivo literario- y árabe, entendiendo acaso el griego y el latín.…

  16. Vy jste mi z té otázky utekl (analýza jednoho způsobu vymáhání odpovědi s využitím korpusových dokladů)

    Czech Academy of Sciences Publication Activity Database

    Jílková, Lucie

    2015-01-01

    Roč. 97, č. 1 (2015), s. 31-11 ISSN 0008-7386 R&D Projects: GA ČR GAP406/12/1829 Institutional support: RVO:68378092 Keywords : the expression vy mi utíkáte z otázky * the SYN2013PUB corpus * the DIALOG corpus, metaphor Subject RIV: AI - Linguistics

  17. Bērnu mārketinga attīstība Latvijas lielāko pārtikas produktu ražotāju tirgus darbībās

    OpenAIRE

    Lūse, Ieva

    2010-01-01

    Uzņēmumi visā pasaulē arvien vairāk sāka apzināties bērnu potenciālu tirgū un aktivizē savu komunikāciju ar bērnu auditoriju. Bērni vienlaicīgi tirgū pilda vairākas lomas kā patērētāji, iniciatori, ietekmētāji un lēmēji par pirkumu un pircēji šodien un nākotnē, kļūstot par daudzu uzņēmumu produkcijas pamata patērētājiem. Ņemot vērā tēmas aktualitāti autore par maģistra darba mērķi izvirza apzināt un analizēt lielāko Latvijas pārtikas produktu ražotāju aktivitāti bērnu mārketing...

  18. Opryszczkowe zapalenie mózgu przebiegające w postaci szybko narastającego zespołu otępiennego u chorej na reumatoidalne zapalenie stawów, leczonej infliksymabem

    Directory of Open Access Journals (Sweden)

    Justyna Swarowska-Knap

    2011-06-01

    Full Text Available Przedstawiono przypadek 53-letniej chorej na reumatoidalnezapalenie stawów (RZS o ciężkim, opornym na standardoweleczenie przebiegu, leczonej wieloma lekami modyfikującymi przebiegchoroby (LMPCh oraz glikokortykosteroidami, u którejw trakcie leczenia antycytokinowego (infliksymabem wystąpiłyobjawy szybko narastającego zespołu otępiennego. Ze względu nacoraz powszechniejsze zastosowanie leków antycytokinowych nietylko w dziedzinie reumatologii, coraz częściej w literaturze światowejpojawiają się doniesienia o związanych z ich stosowaniemdziałaniach niepożądanych, w tym powikłaniach infekcyjnychi zaburzeniach ze strony ośrodkowego układu nerwowego. Zaburzenianeurologiczne obserwowano w trakcie leczenia wszystkimiinhibitorami czynnika martwicy nowotworów α (tumour necrosisfactor α – TNF-α. Wśród nich występowały: parestezje (65% chorych,zaburzenia widzenia związane z zapaleniem nerwu wzrokowego(40% chorych i splątanie (25% chorych. Ponadto, wgdanych literaturowych, u chorych na RZS leczonych immunosupresyjnieistnieje większe niż w populacji ogólnej ryzyko poważnychinfekcji oraz reaktywacji latentnych infekcji wirusowych,w tym infekcji wirusami z rodziny Herpesviridae i wirusem JC. Ze względu na możliwy związek szybko ujawniających się zaburzeńneurologicznych z leczeniem infliksymabem wysunięto u pacjentkipodejrzenie postępującej wieloogniskowej leukoencefalopatii(progressive multifocal leukoencephalopathy – PML, będącej wynikiemaktywacji utajonej infekcji wirusem JC. W wykonanym badaniuMRI mózgowia stwierdzono obecność hiperintensywnychzmian zlokalizowanych w istocie białej oraz szarej płatów czołowychi skroniowych, które nie dawały efektu masy (ryc. 1. Lokalizacjazmian w płatach skroniowych była typowa dla opryszczkowegozapalenia mózgu (herpes simplex encephalitis – HSE, aleobecnie wiadomo, że podobne zmiany mogą także występowaćw PML. Obie neuroinfekcje mogą przebiega

  19. Crystal structure of the regulatory subunit of archaeal initiation factor 2B (aIF2B) from hyperthermophilic archaeon Pyrococcus horikoshii OT3: a proposed structure of the regulatory subcomplex of eukaryotic IF2B

    International Nuclear Information System (INIS)

    Kakuta, Yoshimitsu; Tahara, Maino; Maetani, Shigehiro; Yao, Min; Tanaka, Isao; Kimura, Makoto

    2004-01-01

    Eukaryotic translation initiation factor 2B (eIF2B) is the guanine-nucleotide exchange factor for eukaryotic initiation factor 2 (eIF2). eIF2B is a heteropentameric protein composed of α-ε subunits. The α, β, and δ subunits form a regulatory subcomplex, while the γ and ε form a catalytic subcomplex. Archaea possess homologues of α, β, and δ subunits of eIF2B. Here, we report the three-dimensional structure of an archaeal regulatory subunit (aIF2Bα) from the hyperthermophilic archaeon Pyrococcus horikoshii OT3 determined by X-ray crystallography at 2.2 A resolution. aIF2Bα consists of two subdomains, an N-domain (residues 1-95) and a C-domain (residues 96-276), connected by a long α-helix (α5: 78-106). The N-domain contains a five helix bundle structure, while the C-domain folds into the α/β structure, thus showing similarity to D-ribose-5-phosphate isomerase structure. The presence of two molecules in the crystallographic asymmetric unit and the gel filtration analysis suggest a dimeric structure of aIF2Bα in solution, interacting with each other by C-domains. Furthermore, the crystallographic 3-fold symmetry generates a homohexameric structure of aIF2Bα; the interaction is primarily mediated by the long α-helix at the N-domains. This structure suggests an architecture of the three subunits, α, β, and δ, in the regulatory subcomplex within eIF2B

  20. Ot porolona k iskusstvu / Kristiina Verbitskaja

    Index Scriptorium Estoniae

    Verbitskaja, Kristiina

    2004-01-01

    Tallinna endise tehase "Polümeer" ruumides tegutsevad juba kaks aastat muusikud, kunstnikud ja teised kultuuriinimesed. 10. -20. augustini toimuvad kultuuritehase Polymer avamisüritused: teatrietendused, kunstinäitused, kontserdid, filmiseansid. Korraldab Madis Mikkor

  1. Poslanije ot propavshih ekspeditsi / Aleksandra Manukjan

    Index Scriptorium Estoniae

    Manukjan, Aleksandra

    2001-01-01

    Kadunud ekspeditsioonidele pühendatud näitusest (mereteemalised pildid ja paberist jäämäed peidetud proviandiga) Tallinna Meremuuseumis, autoriteks Roman Matkiewicz ja Aleksandr Belanov (Moskva, rühmitus MEKVA). Lühidalt rühmitusest Mekva.

  2. Loomakujukesed Valma keskneoliitilises kaksikmatuses / Mirja Ots

    Index Scriptorium Estoniae

    Ots, Mirja

    2010-01-01

    Artiklis käsitletakse Valma keskneoliitilisest asulakohast avastatud mehe ja naise ühishauast leitud sarvest ja merevaigust loomakujukesi. Ülevaade haua avastamisest, hauapanuste leiust, kujukeste võimalikust päritolust, funktsioonist ja tähendusest

  3. God ot goda populjarneje / Aadu Kana

    Index Scriptorium Estoniae

    Kana, Aadu

    2005-01-01

    Parima betoonehitise konkursist. Aasta betoonehitis 2004 - Ülemiste hotell, arhitekt Martin Aunin, projekteerija AS EA Reng, konstruktsioonid: IB Pike, ehitaja AS FKSM, betoon: AS HC Betoon. Eeriauhinnad: Rakvere spordihalli ja Veskimöldre lasteaia betoonelementide tootja E-Betoonelement, IB Pike ja Tiit Masso City Plaza konstruktsioonide eest, Kakumäel asuva eramu tellija ja sisekujundaja Raina Lillepõld

  4. Sedamoodi 2005 : moda ot shkolnikov / Marina Poltavtseva

    Index Scriptorium Estoniae

    Poltavtseva, Marina

    2005-01-01

    Tallinna koolide õpilaste moekonkursist "Sedamoodi" räägib konkursi organisaator Tallinna Kanutiaia Noortemaja direktor Mari Velleste. Sedamoodi 2005 eri vanusegruppide võitjad. Rändauhinnaks on Tauno Kangro skulptuur

  5. Ot rokoko do romantizma / Jevgeni Ashihmin

    Index Scriptorium Estoniae

    Ashihmin, Jevgeni

    2006-01-01

    Suveekskursioonide tsüklist "Eesti kunsti ajaloost" Kumus. Ekskursioonid teemadel "Rokokoost romantismini","Modernism. II Maailmasõja eelne eesti kunst" ja "Eesti kunst nõukogude perioodil". Ekskursioone juhivad kunstiteadlased Helena Risthein ja Karin Taidre

  6. Ot Kannskogo festivalja kruzhitsja golova / Jaak Lõhmus

    Index Scriptorium Estoniae

    Lõhmus, Jaak

    2008-01-01

    Cannes'i 61. filmifestivalist, lähemalt Woody Alleni filmist "Vicky, Cristina, barcelona ja võistlusprogrammi avafilmist "Pimedus" (režissöör Fernando Meirelles). Ka Veiko Õunpuust, kes on saabunud Euroopa talendi auhinda vastu võtma

  7. Ofitserski mundir ot Hugo Boss / Mark Ostanin

    Index Scriptorium Estoniae

    Ostanin, Mark

    2003-01-01

    Antikvaarsete esemete laat Kurtnas. Müügil olevatest ajaloolistest rekonstruktsioonidest. Saksa armee ohvitserimundri taastamise keerulisusest rohkete vigur-detailide tõttu. Mundri disainerina mainitakse Hugo Bossi

  8. Exploring Cultural Competence amongst OT Students.

    Science.gov (United States)

    Govender, Pragashnie; Mpanza, December M; Carey, Tarryn; Jiyane, Kwenzile; Andrews, Bicolé; Mashele, Sam

    2017-01-01

    Occupational therapy relies primarily on communication between the therapist and client for effective intervention. Adequate communication may be influenced by language and cultural differences between the therapist and client. Cultural competence in relation to language and culture is thus a vital part in practice. Limited research exists on cultural competence in occupational therapy students. This study thus aimed to explore the cultural competence of final year students and their perceptions of their own cultural competence, with respect to language and culture in their practice as students. An explorative qualitative study design was utilised with a nonprobability purposeful sample of 21 final year undergraduate students at a tertiary institute in South Africa. Three focus groups were conducted, comprising between 6 and 8 students in each group. Thematic analysis using inductive reasoning was undertaken in order to analyse the students' experiences and understanding of cultural competence. Findings of the study suggest that cultural competence, in relation to language and culture, influences the occupational therapy intervention process. It was shown to both positively and negatively influence intervention through supporting or hindering rapport building, client centeredness, and effective intervention.

  9. Tõsielust midagi jaburamat ei ole / Kristjan Ots

    Index Scriptorium Estoniae

    Ots, Kristjan

    2004-01-01

    PÖFFi filme - mängufilmid "Kadudega tuleb arvestada" ("Mit Verlust ist zu Rechnen") : režissöör Ulrich Seidl : Austria 1992 ja "Tş̌ehhi unelm" ("Česky sen") : režissöörid Vit Klusak ja Filip Remunda : Tšehhi 2004

  10. Exploring Cultural Competence amongst OT Students

    Directory of Open Access Journals (Sweden)

    Pragashnie Govender

    2017-01-01

    Full Text Available Occupational therapy relies primarily on communication between the therapist and client for effective intervention. Adequate communication may be influenced by language and cultural differences between the therapist and client. Cultural competence in relation to language and culture is thus a vital part in practice. Limited research exists on cultural competence in occupational therapy students. This study thus aimed to explore the cultural competence of final year students and their perceptions of their own cultural competence, with respect to language and culture in their practice as students. An explorative qualitative study design was utilised with a nonprobability purposeful sample of 21 final year undergraduate students at a tertiary institute in South Africa. Three focus groups were conducted, comprising between 6 and 8 students in each group. Thematic analysis using inductive reasoning was undertaken in order to analyse the students’ experiences and understanding of cultural competence. Findings of the study suggest that cultural competence, in relation to language and culture, influences the occupational therapy intervention process. It was shown to both positively and negatively influence intervention through supporting or hindering rapport building, client centeredness, and effective intervention.

  11. Results of a M = 5.3 heat transfer test of the integrated vehicle using phase-change paint techniques on the 0.0175-scale model 56-OTS in the NASA/Ames Research Center 3.5-foot hypersonic wind tunnel

    Science.gov (United States)

    Marroquin, J.

    1985-01-01

    An experimental investigation was performed in the NASA/Ames Research Center 3.5-foot Hypersonic Wind Tunnel to obtain supersonic heat-distribution data in areas between the orbiter and external tank using phase-change paint techniques. The tests used Novamide SSV Model 56-OTS in the first and second-stage ascent configurations. Data were obtained at a nominal Mach number of 5.3 and a Reynolds number per foot of 5 x 10 to the 6th power with angles of attack of 0 deg, +/- 5 deg, and sideslip angles of 0 deg and +/- 5 deg.

  12. Identity of Innovative Multifunctional Material Manufacturing Business in Latvia / Inovatīvu Daudzfunkcionālo Materiālu Ražotāju Identitāte Latvijā

    Science.gov (United States)

    Geipele, I.; Staube, T.; Ciemleja, G.; Zeltins, N.; Ekmanis, Yu.

    2015-08-01

    The publication comprises the results from the practical scientific investigation to define the profile and distinctions of the Latvian innovative multifunctional material manufacturing industry. The research is carried out by a holistic approach, including expert interviews, qualitative analysis of the official register data, practical survey, and financial data analysis. The paper seeks to give the detailed data on a technological profile of the mentioned representative companies, if there is a synergy or tough competition in the Latvian market. The current research is topical, because it is unique and does not have analogues in Latvia, and the research is timely due to correspondence with recently stated Research and Innovation Strategies for Smart Specialisation in Latvia. The main findings are associated with recognition of the factors that make impact on commercialisation of the finished goods, obtained financial results and planned directions of development of the respondent companies. Publikācija sniedz veiktā zinātniski praktiskā pētījuma rezultātus, kura ietvaros tika noteikts Latvijas inovatīvu daudzfunkcionālo materiālu ražotāju darbības profils un identitāte. Pētījumā tika izmantota kompleksās analīzes metode, kas ietvēra ekspertu intervijas, uzņēmumu oficiāli reģistrēto datu kvalitatīvo analīzi, zinātniski praktisko aptauju, kā arī pētāmo uzņēmumu finanšu darbības rezultātu analīzi. Zinātniskais darbs sniedz izsmeļošu informāciju par mērķa uzņēmumu tehnoloģisko profilu un pēta, vai Latvijas mērķa ražošanas nozarē ir sinerģijas vai sīvās konkurences pazīmes. Šim zinātniskajam pētījumam ir noteikta aktualitāte saskaņā ar tā unikalitāti Latvijas valsts mērogā un atbilstība Viedās specializācijas stratēģijai. Pētījuma galvenie secinājumi ir saistīti ar uzņēmumu produkcijas komercializācijas ietekmējošo faktoru apzināšanu, sasniegtajiem finansiālajiem rezultātiem un pl

  13. Excretion of radium in relation to dietary intake; Excretion de radium en fonction de l'ingestion alimentaire; Vydelenie radiya v zavisimosti ot priema ego s pishchej; Excrecion de radio en relacion con su absorcion con los alimentos y el agua

    Energy Technology Data Exchange (ETDEWEB)

    Turner, R. C. [Institute of Cancer Research, Royal Cancer Hospital, London (United Kingdom)

    1963-02-15

    srednej velichiny potrebleniya radiya odnim chelovekom iz ehtikh istochnikov sredi ryada professional'nykh grupp, ravno kak sredi grupp naseleniya razlichnykh rajonov strany. Nesmotrya na shirokij interval velichin aktivnosti produktov pitaniya, srednie velichiny priema malo otlichayutsya drug ot druga u raznykh grupp, pri ehtom oni koleblyutsya mezhdu 2 i 3 mmkkyuri na cheloveka v den'. Soderkhanie radiya v pit'evoj vode v Anglii menyaetsya v diapazone koehffitsientov ot 250 do 1, no v bol'shinstve sluchaev absolyutnye urovni nastol'ko nizki po sravneniyu s urovnem v osnovnykh produktakh pitaniya, chto srednie velichiny potrebleniya radiya s vodoj sostavlyayut lish' 5 - 6% ot srednikh obshchikh kolichestv radiya, pogloshchaemogo kazhdym individuumom. Lish' v odnom rajone strany, v kotorom -prozhivaet men'she odnogo protsenta vsego naseleniya, dnevnoe potreblenie radiya s vodoj prevyshaet potreblenie ego s pishchej. Izmereniya vydelenij s isprazhneniyami v rezul'tate normal'nogo priema pishchi pokazyvaet, chto u vzroslykh molodykh lyudej srednee kolichestvo radiya-226, vydelyaemogo takim putem, sostavlyaet 2-2,5 mmkkyuri v den'. Ehta tsifra soglasuetsya s vychislennymi dannymi srednego dnevnogo priema. Issledovaniya metabolizma u lyudej pokazyvayut, chto bol'shaya chast' sutochnogo kolichestva radiya, prinyatogo s pishchej, vydelyaetsya v techenie 24 - 48 chasov, no popytki opredelit' fraktsionnoe uderzhanie radiya u vzroslykh privodyat k neodinakovym rezul'tatam. Izmereniya velichin dnevnogo priema i vydeleniya s isprazhneniyami u malen'kikh detej v techenie 33 dnej ukazyvayut na to, chto uderzhanie radiya v periody aktivnogo rosta kostej mozhet sostavlyat' do 10% ili bolee ot obshchego kolichestva radiya, prinyatogo vnutr'. (author)

  14. Fluktuacja dynamiki i dymorfizm płciowy cech somatycznych, typu budowy i otłuszczenia ciała dzieci i młodzieży w wieku od 4 do 18 lat środowiska wiejskiego regionu warmińsko-mazurskiego

    Directory of Open Access Journals (Sweden)

    Mirosław Mrozkowiak

    2015-07-01

    Mirosław Mrozkowiak   Mirosław Mrozkowiak Bioergonsport, Nowa Biała. Polska e-mail: magmar54@interia.pl strona: http://wadypostawy.republika.pl   Słowa kluczowe: wysokość i masa ciała, wskaźnik BMI, IR.   Streszczenie Wstęp. Mimo sekularnego zwiększenia wysokości ciała we wszystkich grupach i płciach, dystanse międzyśrodowiskowe nie wykazywały tendencji malejących, jednak wszystkie populacje dążą do pewnej stabilizacji. Powszechnie stosowany wskaźnik wagowo-wzrostowym BMI umożliwił diagnostykę otyłości i nadwagi, a wskaźnik IR określenie typu budowy ciała. Celem badań jest określenie dynamiki zmian i dymorfizmu płciowego cech somatycznych, typu budowy i otłuszczenia ciała dzieci i młodzieży w wieku od 4 do 18 lat środowiska wiejskiego, regionu warmińsko-mazurskiego Polski. Metoda i materiał. Z badań uzyskano 8270 obserwacji w tym 3384 wśród dziewcząt i 3786 chłopców. Pomiarów dokonano na wadze lekarskiej z dokładnością do 0,5 cm i 100 g. Wyniki. Statystykę opisową wskaźnika BMI przedstawiono w tab. 2 oraz ryc. 1. Dynamikę zmian i istotność różnic między płciami w kategoriach wiekowych w tab. 3 i 4 oraz ryc. 2. Statystykę opisową wskaźnika IR przedstawiono w tab. 5 i ryc. 3. Dynamikę zmian i istotność różnic między płciami w kategoriach wiekowych w tab. 6 i 7 oraz ryc. 4. W tab. 8 przedstawiono przyjętą interpretację wskaźnika IR, w 9 wskaźnika BMI, w tab. 10, 11 i 12 oraz ryc. od 5 do 9 przedstawiony jest odsetek typów budowy i otłuszczenia występujący w badanej kohorcie. Wnioski. 1. Średnia wysokość i masa ciała chłopców w wieku od 4 do 18 r.ż. jest większa niż dziewcząt w tym samym wieku. 2. Wśród dziewcząt i chłopców dominuje smukły typ budowy ciała. Wśród chłopców w wieku 17 lat występuje tylko typ smukły, a w 18 r.ż. średni. 3. Odsetek z niedowagą utrzymuje się na wysokim poziomie wśród dziewcząt i chłopców do 8 r.ż., później sukcesywnie obni

  15. Surface potential domains on lamellar P3OT structures

    Energy Technology Data Exchange (ETDEWEB)

    Perez-GarcIa, B [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Abad, J [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Urbina, A [Departamento Electronica, TecnologIa de Computadoras y Proyectos, Universidad Politecnica de Cartagena, E-30202 Cartagena (Spain); Colchero, J [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain); Palacios-Lidon, E [Departamento Fisica, Facultad de Quimica (Campus Espinardo), Universidad de Murcia, E-30100 Murcia (Spain)

    2008-02-13

    In this work the electrostatic properties of poly(3-octylthiophene) thin films have been studied on a nanometer scale by means of electrostatic force microscopy and Kelvin probe microscopy (KPM). The KPM images reveal that different surface contact potential domains coexist on the polymer surface. This result, together with additional capacitance measurements, indicates that the potential domains are related to the existence of dipoles due to different molecular arrangements. Finally, capacitance measurements as a function of the tip-sample bias voltage show that in all regions large band bending effects take place.

  16. ater hy ater uota Systems In hina are ot orkin

    International Development Research Centre (IDRC) Digital Library (Canada)

    commerce and urban communities compete for ... China's Heihe River Basin by Junlian Zhang, College of Resource and Environment,. China Agricultural ... Adherence to water quotas in five irrigation areas in Zhangye City. Hongshuihe. 4.1.

  17. Treatability study Number PDC-1-O-T. Final report

    International Nuclear Information System (INIS)

    1998-01-01

    Los Alamos National Laboratory provided treatability study samples from four waste streams, designated Stream number-sign 1, Stream number-sign 3, Stream number-sign 6, and Stream number-sign 7. Stream number-sign 1 consisted of one 55-gallon drum of personal protective equipment (PPE), rags, and neutralizing agent (bicarbonate) generated during the cleanup of a sodium dichromate solution spill. Stream number-sign 3 was one 55-gallon drum of paper, rags, lab utensils, tools, and tape from the decontamination of a glovebox. The sample of Stream number-sign 6 was packaged in three 30-gallon drums and a 100 ft 3 wooden box. It consisted of plastic sheeting, PPE, and paper generated from the cleanup of mock explosive (barium nitrate) from depleted uranium parts. Stream number-sign 7 was scrap metal (copper, stainless and carbon steel joined with silver solder) from the disassembly of gas manifolds. The objective of the treatability study is to determine: (1) whether the Perma-Fix stabilization/solidification process can treat the waste sample to meet Land Disposal Restrictions and the Waste Acceptance Criteria for LANL Technical Area 54, Area G, and (2) optimum loading and resulting weight and volume of finished waste form. The stabilized waste was mixed into grout that had been poured into a lined drum. After each original container of waste was processed, the liner was closed and a new liner was placed in the same drum on top of the previous closed liner. This allowed an overall reduction in waste volume but kept waste segregated to minimize the amount of rework in case analytical results indicated any batch did not meet treatment standards. Samples of treated waste from each waste stream were analyzed by Perma-Fix Analytical Services to get a preliminary approximation of TCLP metals. Splits of these samples were sent to American Environmental Network's mixed waste analytical lab in Cary, NC for confirmation analysis. Results were all below applicable limits

  18. Kontrastõ ot Baltika Grupp / Jana Kuvaitseva

    Index Scriptorium Estoniae

    Kuvaitseva, Jana

    2007-01-01

    Eesti rõivatootja Baltika Grupp uutest sügis-talvistest kollektsioonidest räägivad Montoni kaubamärgi disainerid Jaanika Sootna ja Evelin Lill ning Ivo Nikkolo kaubamärgi disainer Eve Hanson. Baltika kaubamärgid on Monton, Mosaic, Baltman ja Ivo Nikkolo

  19. Surface potential domains on lamellar P3OT structures

    International Nuclear Information System (INIS)

    Perez-GarcIa, B; Abad, J; Urbina, A; Colchero, J; Palacios-Lidon, E

    2008-01-01

    In this work the electrostatic properties of poly(3-octylthiophene) thin films have been studied on a nanometer scale by means of electrostatic force microscopy and Kelvin probe microscopy (KPM). The KPM images reveal that different surface contact potential domains coexist on the polymer surface. This result, together with additional capacitance measurements, indicates that the potential domains are related to the existence of dipoles due to different molecular arrangements. Finally, capacitance measurements as a function of the tip-sample bias voltage show that in all regions large band bending effects take place

  20. Polnõi shabash ot Emira Kusturitsõ

    Index Scriptorium Estoniae

    2001-01-01

    Emir Kusturica esines orkestri No Smoking Orchestra koosseisus Moskvas ja Peterburis. Sellest juba 1980. aastal Sarajevos loodud orkestrist on ta teinud dokumentaalfilmi "Super 8 Stories by Emir Kusturica"

  1. Elaboration d'entrep\\^ots de donn\\'ees complexes

    OpenAIRE

    Teste, Olivier

    2010-01-01

    In this paper, we study the data warehouse modelling used in decision support systems. We provide an object-oriented data warehouse model allowing data warehouse description as a central repository of relevant, complex and temporal data. Our model integrates three concepts such as warehouse object, environment and warehouse class. Each warehouse object is composed of one current state, several past states (modelling its detailed evolutions) and several archive states (modelling its evolutions...

  2. Film o katastrofje "Estonii" budjet javno daljok ot deistvitelnosti

    Index Scriptorium Estoniae

    2001-01-01

    Kavandatavast katastrooffilmist "Baltic Storm", mis on ajendatud väidetest, et parvlaev "Estonia" uputati. Stsenaristiks on saksa teleajakirjanik Jutta Rabe, kes koos advokaat Kaj Holmbergiga lõi selleks puhuks stuudio Top Story. Peaosalisi mängivad Greta Scacchi (41) ja Jürgen Prochnow (60)

  3. Intercomparison ot the PTB and LMRI standards in beta dosimetry

    International Nuclear Information System (INIS)

    Hillion, P.; Simoen, J.P.; Boehm, J.

    1976-12-01

    To set up national standard measuring devices for verifying the unit of the quantity 'absorbed dose rate in soft tissue' at different depths for β-radiation, extrapolation chambers have been developed at the PTB and LMRI. They are constructed of nearly tissue equivalent materials and connected to measuring devices of highest metrological quality. A comparison of these standards has been carried out using two β-ray sources of 90 Sr + 90 Y, one from each laboratory. Absorbed dose rates between 0,5 Gy h -1 and 1.3 Gy -1 have been determined. The overall uncertainties of the absorbed dose rates in tissue are 1.8%. The part of the uncertainty due to systematic uncertainties of corrections unique for each laboratory amounts to 0.8% for the LMRI and 0.7% for the PTB. The ratios of the corresponding absorbed dose rates measured at the PTB and at the LMRI differ by 0.2% to 0.7%. On the average, the LMRI values are 0.4% samller than the PTB values. The agreement is felt to be very satisfactory. (orig.) [de

  4. Pirozhki s izjuminkoi ot Suini i Ko / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2008-01-01

    Õudusmuusikal "Sweeney Todd : Fleet Streeti deemonlik habemeajaja" Stephen Sondheimi muusikali alusel : režissöör Tim Burton : peaosades Johnny Depp, Helena Bonham Carter : Ameerika Ühendriigid - Suurbritannia 2007

  5. JeS zhdjot ot Rossii podtverzhdenija / Marko Saaret

    Index Scriptorium Estoniae

    Saaret, Marko

    2004-01-01

    Euroopa Komisjoni president Romano Prodi, välisasjade komissar Chris Patten ja kaubandusvolinik Pascal Lamy alustavad visiiti Moskvasse. Venemaalt oodatakse lõplikku kinnitust kirjutamaks alla partnerluse ja koostöö lepingu laienemisele uute EL-i riikidega enne 1. maid

  6. "Kalev" izbavilsja ot pishtshevõhh "dobavok" / Hilda Vall

    Index Scriptorium Estoniae

    Vall, Hilda

    2007-01-01

    Ärimees Oliver Kruuda teatas oma piimatööstuse Tere ja kondiitritööstuse Kalev müügist Eesti investeerimisfirmale Alta Capital Partners, põhjendades oma otsust sooviga edaspidi tegutseda kinnisvara ja meedia vallas

  7. 12 CFR 574.7 - Determination by the OTS.

    Science.gov (United States)

    2010-01-01

    ... days of such request on the competitive factors involved. Acquisitions involving mergers (including...) [Reserved] (g) Presumptive disqualifiers—(1) Integrity factors. The following factors shall give rise to a...) Violation of the rules, regulations, codes of conduct or ethics of a self-regulatory trade or professional...

  8. Tshto nuzhno amerikantsam ot rossiskoi zhivopisi / Natalia Kolodzei

    Index Scriptorium Estoniae

    Kolodzei, Natalia

    2004-01-01

    Intervjuu Washington ProFile'ilt vene- ja nõukogude kunsti erakogu baasil loodud fondi "Kolodzei Art Foundation" (1991) ühe rajaja, tegevdirektori ja kuraatoriga nõukogude ja vene kunsti propageerimisest ja näituste korraldamisest USA-s

  9. Kunstniku nimi paanidena seinal / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Luksuslikest disaintapeetidest, mis kannavad kunstniku nime. Inglise kunstniku William Morrise (1834-1896) kujundatud tapeete müüakse Morris&Co nime all. Huvitavaid disaintapeete pakub firma Disain Digest, kust leiab Sahco Hessleini, Ulf Moritza jt. kujundatud tapeete

  10. Mozhet li natsija zashtshitit ot natsionaliszma? / Sergei Ivanov

    Index Scriptorium Estoniae

    Ivanov, Sergei, 1958-

    2006-01-01

    Euroopa Nõukogu Parlamentaarne Assamblee (ENPA) käsitleb küsimust, kas rahvuse mõiste täpsustamine võib aidata tagada rahvusvähemuste õigusi 21. sajandi Euroopas. Rahvuse mõiste muutumisest läbi ajaloo, ENPA seisukohtadest, mis puudutavad rahvusvähemusi

  11. Letni sezon : ot avangardista do "Sjurrealistov" / Boris Tuch

    Index Scriptorium Estoniae

    Tuch, Boris, 1946-

    2006-01-01

    Suvelavastustest: Andrus Kivirähk "Sürrealistid" Viinistus (lavastaja Hendrik Toompere jun), Mart Kivastik "Kits viiuli ja õngega" Viinistus (lavastaja Raimo Pass), Alfred Jarry "Kuningas Ubu" Teater NO99 Haapsalu Kiltsi lennuvälja angaarides (lavastajad Ene-Liis Semper ja Tiit Ojasoo), Jaan Tätte "Kaev" Tallinna Linnateatri siseõues (lavastaja Indrek Sammul)

  12. JUNESKO v uzhase ot tsentra "Viru" / Jekaterina Rodina

    Index Scriptorium Estoniae

    Rodina, Jekaterina

    2005-01-01

    UNESCO maailmapärandi komitee ekspert arutas Tallinna linnavõimudega bastionide ja linnamüüri kasutamise ning linna merele avamise küsimusi. Ekspert kritiseeris Tallinna linnaplaneerimist, näitena tõi Viru Keskuse vanalinna läheduses

  13. An OT Account of Laryngealization in Cuzco Quechua.

    Science.gov (United States)

    Parker, Steve

    Classical phonemic accounts of Cuzco (Peru) Quechua posit three distinct types of stops: plain, aspirated, and glottalized. A later analysis argued instead for a root-level feature of laryngealization governed by a small number of formal mechanisms. This latter analysis is taken one step further, showing that even greater explanatory power may be…

  14. Speed ot travelling waves in reaction-diffusion equations

    International Nuclear Information System (INIS)

    Benguria, R.D.; Depassier, M.C.; Mendez, V.

    2002-01-01

    Reaction diffusion equations arise in several problems of population dynamics, flame propagation and others. In one dimensional cases the systems may evolve into travelling fronts. Here we concentrate on a reaction diffusion equation which arises as a simple model for chemotaxis and present results for the speed of the travelling fronts. (Author)

  15. Analysis of the On the Spot (OTS) Road Accident Database

    NARCIS (Netherlands)

    Mansfield, H.; Bunting, A.; Martens, M.; Horst, A.R.A. van der

    2008-01-01

    The UK Government is seeking to substantially reduce the number of road traffic accidents (RTAs) leading to injury or loss of life. Specifically, relative to the average figures for 1994–98, the Government would like to meet the following road casualty reduction targets by 2010: • a 40% reduction in

  16. EFFECT OT KUNNU-ZAKI ON CLINICAL BACTERIAL ISOLATES

    African Journals Online (AJOL)

    omidiji

    2012-03-08

    Mar 8, 2012 ... S. aureus. 14. -. -. -. 12.5 ... S. paratyphi. 13.5. 11.5 ... Wells were then cut with flame-sterilized size 3 cork-borer, followed .... Prevalence of S. aureus in meat samples ... drink (Kunnu-zaki): Effect of spices pH and temperature.

  17. Physical environment at school : treatments and perspectives / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone

    2008-01-01

    Artiklis vaadeldakse füüsilise keskkonna määratlust nüüdisaja hariduse paradigmas. 20. sajandi mõtlejate seisukohti ja rakendusuuringute tulemusi füüsilise keskkonna üksikute elementide mõju kohta õpitulemustele. Kas virtuaalne õpikeskkond võib välja vahetada füüsilise

  18. Mozarti mõõtmed ehk lavastajate kool / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone, 1965-

    2010-01-01

    17. oktoobril Rahvusooperis Estonia esietendunud Mozarti koomilisest ooperist "Cosi fan tutte ossia La scuola degli amanti", lavastaja Walter Sutcliffe, etenduse muusikaline juht ja dirigent Arvo Volmer

  19. Ot Gannibala do "Russkogo bunta" / Tatjana Mühlbeier

    Index Scriptorium Estoniae

    Mühlbeier, Tatjana

    2000-01-01

    Eestis elanud legendaarsest A. Pushkini vaarisast Abram Hannibalist ja temaga seoses ka sama ajastut kujutavast vene režissööri Aleksandr Proshkini uuest ajaloolisest mängufilmist "Vene mäss" ("Russki bunt")

  20. Ot Tallsinki do Hellinna 80 km / Aleksandr Kulakov

    Index Scriptorium Estoniae

    Kulakov, Aleksandr

    2005-01-01

    23. kuni 25. septembrini toimus Helsingis Soome noorteühenduse TOK poolt korraldatud meediaseminar, kus osalesid vene keelt kõnelevad noored Eestist ja Soomest, ajakirjanikud ja noortega töötavad spetsialistid. Seminari eesmärgiks oli luua kontakte noorte ja vanemate loomeinimeste vahel ning leida võimalusi informatsiooni vahetamiseks ja koostöö arendamiseks erinevates riikides elavate venekeelsete noorte vahel

  1. COGORT METHOD AND OTS APPLICATIONS TO INSURANCE STATICTICS

    Directory of Open Access Journals (Sweden)

    Yu. F. Kasimov

    2014-01-01

    Full Text Available The paper considers the so-called cohort method of accounting aggregates insurance portfolios. In insurance statistics systematization and processing of aggregate data on the issued policies, premiums and insurance payments are often made with gross errors, because ones don't set the criteria written policies and related payments to the analyzed statistical universe. Besides, it is often not clearly specify the scheme of calculation of aggregate statistical associated with these policies. The study gives a detailed and rigorous presentation as a method of formation of different cohorts data for a specified period of assessment the aggregated characteristics and methods of calculation of interest to insurance of indicators (absolute and relative for these cohorts. The knowledge of these methods is necessary for a correct assessment of insurance premiums and reserves.

  2. Veiko Õunpuu polutshit premiju ot ES

    Index Scriptorium Estoniae

    2008-01-01

    Cannes'i filmifestivali raames toimuval Euroopa päeval antakse filmirežissöör Veiko Õunpuule üle Euroopa Talendi auhind (European Talent Prize) mängufilmiprojekti "Püha Tõnu Kiusamine" eest (produtsent Katrin Kissa)

  3. Report: Ozone Transport Commission Incurred Costs Under EPA Assistance Agreements XA98379901, OT83098301, XA97318101, and OT83264901

    Science.gov (United States)

    Report #2007-4-00068, July 31, 2007. We questioned $2,723,706 of the $9,042,706 in reported outlays because the recipient claimed unallowable outlays for contractual services, indirect costs, and in-kind costs.

  4. Regularities in the Changes of Absorber Material Properties as a Function of Absorber Concentration; Regularite des Variations des Proprietes des Substances Absorbantes en Fonction de la Concentration de l'Absorbant; Zakonomernosti izmeneniya svojstv poglashchayushchikh materialov v zavisimosti ot kontsentratsii poglotitelya; Leyes de Variacion de las Propiedades de los Materiales Absorbentes en Funcion de la Concentracion del Absorbente

    Energy Technology Data Exchange (ETDEWEB)

    Portnoj, K. I.

    1964-06-15

    pouvoir absorbant, en tant que fonction de la concentration de l'absorbant, varie d'apres une courbe caracteristique d'un phenomene de saturation et depend du spectre de neutrons. L'auteur formule une hypothese sur l'obtention du pouvoir absorbant maximum grace a la combinaison de plusieurs absorbants. Cette hypothese a ete largement confirmee par des experiences effectuees, dans des reacteurs a neutrons thermiques et intermediaires, sur de nombreuses combinaisons d'absorbants metalliques ou non. (author) [Spanish] En esta memoria se exponen las leyes que rigen las variaciones de las propiedades mecanicas y termofisicas y del poder de absorcion, en funcion de la concentracion del absorbente, en aleaciones destinadas a los reactores de neutrones termicos e intermedios. La conductividad y el coeficiente de dilatacion termica de las aleaciones absorbentes a base de boro y oxidos de las tierras raras se reducen al aumentar dicha concentracion. En el caso de las aleaciones con oxidos de las tierras raras, la variacion del coeficiente de dilatacion es lineal, mientras que para las alea,- ciones de boro esa caracteristica aditiva se altera. Ello se debe a que a temperaturas elevadas se forman fases de boruro con distintas redes cristalinas. En cuanto al poder absorbente, varia segun una curva de saturacion y depende tambien del espectro neutronico. El autor propone una hipotesis para explicar la aparicion de un maximo en la curva del poder absorbente, que atribuye a un fenomeno de interaleacion de los absorbentes. Esta hipotesis ha sido confirmada ampliamente por los resultados de experimentos efectuados con muchos sistemas absorbentes metalicos y no metalicos, de variada composicion, en reactores de neutrones termicos e intermedios. (author) [Russian] Doklad stavit cel'ju izlozhit' poluchennye zakonomernosti izmenenija mehanicheskih i teplofizicheskih svojstv, a takzhe pogloshhajushhej sposobnosti v zavisimosti ot koncentracii poglotitelej v sp lav a h , prednaznachennyh dlja

  5. Geographic Information Systems in Developing Countries – What are the Ethical Issues we need to be aware of ? / Geografické Informační Systémy A Jejich Využití V Rozvojových Zemích - Jakým Etickým Otázkám Musíme Čelit?

    Directory of Open Access Journals (Sweden)

    Pánek Jiří

    2013-06-01

    Full Text Available Využití geografických informačních systémů (GIS v rozvojových zemích se musí potýkat s historickou skepsí, kterou mapy, jako nástroj moci, mají mezi původními obyvateli. Participativní přístupy v mapování a GIS se snaží přistupovat k místním prostorovým znalostem s větší mírou společenské a etické zodpovědnosti. Článek se soustředí na popis vybraných důvodů, které vedly ke skeptickému postoji vůči GIS, a na identifikaci základních etických otázek sběru a interpretace prostorových informací v rozvojových zemích na příkladu mapování vodních zdrojů ve vesnici Koffiekraal v Jihoafrické republice.

  6. Strain Dependence of the Frequencies and the Thermal Expansion of the Hexagonal Close-Packed Lattice; Variations, en Fonction de la Deformation, des Frequences et de la Dilatation Thermique du Reseau a Structure Hexagonale Compacte; Zavisimost' chastot i teplovogo rasshireniya geksagonal'noj reshetki s plotnoj upakovkoj ot napryazheniya; Variacion de las Frecuencias y de la Dilatacion Termica de la Red Hexagonal Compacta en Funcion de la Deformacion

    Energy Technology Data Exchange (ETDEWEB)

    Srinivasan, R.; Ramji Rao, R. [Physics Department, Indian Institute of Technology, Madras (India)

    1965-04-15

    {gamma}'' Para tres pares de valores de m y n. Se ha comprobado que {gamma}' = {gamma}'' y que el limite superior de temperatura {gamma}{sub {infinity}} mayor en 0,3, aproximadamente, que el limite inferior de temperatura{sup .} Esta diferencia cuya magnitud parece ser independiente de los valores de m y n, disminuira probablemente al tener en cuenta la interaccion de atomos vecinos mas alejados. Los datos teoricos se comparan con los resultados experimentales obtenidos en el caso del magnesio. (author) [Russian] Nedavno bylo izmereno anizotropnoe teplo voe rasshirenie nekotoryh geksagonal'nyh metallov. Dlja razrabotki teorii anizotropnogo teplovogo rasshirenija geksagonal'noj reshetki s plotnoj upakovkoj neobhodimo issledovat' zavisimost' chastot geksagonal'noj reshetki s plotnoj upakovkoj ot naprjazhenija. Rassmatrivalas' geksagonal'naja reshetka s plotnoj upakovkoj s central'nym vzaimodejstviem s bli- a b zhajshim sosednim atomom v vide Empty-Set = -a/{gamma}{sup m} + b/{gamma}{sup n} Ispol'zuemymi naprjazhenijami javljajutsja 1) prodol'noe rasshirenie #Greek Lunate Epsilon Symbol#' vdol' osi z; i 2) ravnomernoe vozdushnoe rasshirenie {zeta} vdol' osnovnoj ploskosti. Oni javljajutsja sootvetstvujushhimi naprjazhenijami v teorii teplovogo rasshirenija,i ih preimushhestvom javljaetsja to, chto oni ne vyzyvajut smeshhenij mezhdu reshetkami. Byli razrabotany parametry Grjunajzena {gamma}'{sub i} = - Partial-Differential log{omega}{sub i}/ Partial-Differential #Greek Lunate Epsilon Symbol#' and {gamma}'{sub i}' = - Partial-Differential log{omega}{sub i}/ Partial-Differential {zeta} Dlja volnovyh vekto- J rov, idushhih vdol' opredelennyh simmetrichnyh napravlenij. Bylo ustanovleno, chto jeti parametry dlja akusticheskih vetvej sil'no zavisjat ot napravlenija i sil'no kolebljutsja. Odna iz poperechnyh akusticheskih vetvej v osnovnoj ploskosti imeet otricatel'noe znachenie {gamma}' dlja ljubyh znachenij ship. Byla opredelena zavisimost' momentov {mu}{sub 2}, {mu}{sub 4} i {mu

  7. Zodpovídání otázek dotazníkového průzkumu: interpretace otázky

    Czech Academy of Sciences Publication Activity Database

    Vinopal, Jiří

    2007-01-01

    Roč. 5, č. 1 (2007), s. 10-14 ISSN 1214-438X R&D Projects: GA AV ČR IAA700280702 Institutional research plan: CEZ:AV0Z70280505 Keywords : Public Opinion * Question Interpretation * Poll Survey Methodology Subject RIV: AO - Sociology, Demography

  8. Ot ritualnite žertvi kăm răčenicata v minižupi (Etnomuzikovedski impresii ot Bălgarija)

    Czech Academy of Sciences Publication Activity Database

    Tyllner, Lubomír

    2015-01-01

    Roč. 41, č. 4 (2015), s. 523-536 ISSN 0323-9861 Institutional support: RVO:68378076 Keywords : ethnomusicology * bulgarian folklore tradition * folk dance * traditional music * music al instruments Subject RIV: AC - Archeology, Anthropology, Ethnology

  9. Investigations of the chemical states of carrier-free phosphorus-32 as extracted into water from pile-irradiated sulphur; Recherches sur les etats chimiques du phosphore-32 sans entraineur obtenu par extraction aqueuse a partir de soufre irradie dans un reacteur; Issledovanie khimicheskogo sostoyaniya svobodnogo ot nositelya fosfora-32 pri izvlechenii ego v vodu iz obluchennoj v yadernom reaktore sery; Estudio de los estados quimicos del fosforo-32 libre de portador que se obtiene por extraccion acuosa del azufre irradiado en un reactor

    Energy Technology Data Exchange (ETDEWEB)

    Dahl, J B; Birkelund, O R [Institutt for Atomenergi, Kjeller, Lillestrom (Norway)

    1962-01-15

    {>=} 5). Aucun metaphosphate (cyclique) n'a ete decele dans la solution lors de la production et du stockage. Les resultats indiquent que les composes de polyphosphore ont ete formes dans le materiau de cible au cours de l'irradiation. On a etudie plus particulierement l'adsorption des composes du phosphore-32 sans entraineur par le verre dans les conditions de l'experience. (author) [Spanish] Uno de los metodos que se emplean para obtener fosforo-32 libre de portador consiste en irradiar azufre en un reactor y extraer con agua el fosforo formado. La presente memoria informa sobre los estados quimicos del fosforo-32 en soluciones acuosas durante las diversas fases del proceso normal de obtencion. Los autores han estudiado tambien las modificaciones que el estado quimico de los compuestos de fosforo-32 experimenta en el producto final, en funcion del tiempo de almacenamiento. Han encontrado que el fosforo-32 aparece principalmente en forma de orto-fosfato. La proporcion de ortofosfato aumenta durante el tratamiento quimico; al comenzar la extraccion, es del orden del 70 por ciento, en tanto que alrededor del 98 por ciento del fosforo-32 libre de portador obtenido como producto final se encuentra bajo forma de ortofosfato. Los componentes restantes de la mezcla consisten en piro-, tri-, tetra- y polifosfatos de cadena larga (con un numero de atomos de fosforo {>=} 5). Durante la elaboracion y almacenamiento los autores no han encontrado metafosfatos (ciclicos) en ninguna de las soluciones. Los resultados obtenidos indican que los compuestos polifosforicos se formaron en el material del blanco durante la irradiacion. Los autores han prestado especial atencion al estudio de la adsorcion de compuestos de fosforo-32 libre de portador por el material de vidrio en las condiciones experimentales. (author) [Russian] Odnim iz sovremennykh metodov polucheniya svobodnogo ot nositelya fosfora-32 yavlyaetsya izvlechenie ego v vodu iz obluchennoj v yader- nom reaktore sery. V

  10. Inglihääled vaiksel ööl / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone, 1965-

    2015-01-01

    Jõululaulust "Püha öö" ("Vaikne öö"), sõnade autor Joseph Franz Mohr, viisi autor Franz Xaver Gruber. Jõulukoraalist "Hõisake, taevad", autor Joachim Neander. Jõulukoraalist "Ma tulen taevast ülevalt", autor Martin Luther

  11. Ajakirja Siluett kasvatuslikust rollist ilmumise esimesel viisaastakul (1958-1963) / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone, 1965-

    2003-01-01

    Analüüsitakse kasvatuslikku rolli pealtnäha moeajakirjas, kuid väljaanne võttis ette moe kõrval ka naiseliku naise taasloomise, vahepeal põluall olnud käitumisnormide, hügieeniharjumuste, maitseka riietumisstiili jt. juba unustatud tarkuste õpetamise, mille abil naine kujuneb harmooniliseks isiksuseks

  12. Tants ei küsi vanust / Ille Grün-Ots, Siiri Rebane

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2007-01-01

    Kanal 2 menusaate "Tantsud tähtedega" järellainetuses vesteldakse artiklis seltskonnatantsust Revalia tantsukooli juhataja Merle Klandorfiga, bailatinost Dance Act direktori Georg Kodusaarega, kõhutantsust tantsuõpetaja Diana Otsinguga ja flamenkost Claudia Shevsthenkoga

  13. OT2_tvelusam_4: Probing Galactic Spiral Arm Tangencies with [CII

    Science.gov (United States)

    Velusamy, T.

    2011-09-01

    We propose to use the unique viewing geometry of the Galactic spiral arm tangents , which provide an ideal environment for studying the effects of density waves on spiral structure. We propose a well-sampled map of the[C II] 1.9 THz line emission along a 15-degree longitude region across the Norma-3kpc arm tangential, which includes the edge of the Perseus Arm. The COBE-FIRAS instrument observed the strongest [C II] and [N II] emission along these spiral arm tangencies.. The Herschel Open Time Key Project Galactic Observations of Terahertz C+ (GOT C+), also detects the strongest [CII] emission near these spiral arm tangential directions in its sparsely sampled HIFI survey of [CII] in the Galactic plane survey. The [C II] 158-micron line is the strongest infrared line emitted by the ISM and is an excellent tracer and probe of both the diffuse gases in the cold neutral medium (CNM) and the warm ionized medium (WIM). Furthermore, as demonstrated in the GOTC+ results, [C II] is an efficient tracer of the dark H2 gas in the ISM that is not traced by CO or HI observations. Thus, taking advantage of the long path lengths through the spiral arm across the tangencies, we can use the [C II] emission to trace and characterize the diffuse atomic and ionized gas as well as the diffuse H2 molecular gas in cloud transitions from HI to H2 and C+ to C and CO, throughout the ISM. The main goal of our proposal is to use the well sampled (at arcmin scale) [C II] to study these gas components of the ISM in the spiral-arm, and inter-arm regions, to constrain models of the spiral structure and to understand the influence of spiral density waves on the Galactic gas and the dynamical interaction between the different components. The proposed HIFI observations will consist of OTF 15 degree longitude scans and one 2-degree latitude scan sampled every 40arcsec across the Norma- 3kpc Perseus Spiral tangency.

  14. Kolmas Nobeli füüsikapreemia elektronõrga vastastikmõju uurijatele / Ilmar Ots

    Index Scriptorium Estoniae

    Ots, Ilmar

    2001-01-01

    1999. a. füüsikapreemia pälvisid hollandi teadlased Gerardus 't Hooft ja Martinus J. G. Veltman tööde eest elektronõrga vastastikmõju valdkonnas. Ettekanne 30. Eesti füüsikapäevadel : Tartu, 2000

  15. Füüsiline keskkond koolis : käsitlusi ja perspektiive / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone

    2007-01-01

    Artiklis vaadeldakse füüsilise keskkonna määratlust nüüdisaja hariduse paradigmas. 20. sajandi mõtlejate seisukohti ja rakendusuuringute tulemusi füüsilise keskkonna üksikute elementide mõju kohta õpitulemustele. Kas virtuaalne õpikeskkond võib välja vahetada füüsilise

  16. Ot "Printsessõ Alissii" k "Hrabromu Rikki-Tikki-Tavi" / Eteri Kekelidze

    Index Scriptorium Estoniae

    Kekelidze, Eteri, 1944-

    2000-01-01

    Tallinna muusikateater Väike Ooper jõudis tagasi Moskva külalisetendustelt, kus Eesti Saatkonnas esitati Boriss Kisseljovi lasteooper ""Printsess Alicia". Sügisel valmistub lasteteater lavale tooma helilooja uut ooperit "Julge Rikki-Tikki- Taavi"

  17. Husserl a otázka tělesnosti jako jádra subjektivity

    Czech Academy of Sciences Publication Activity Database

    Novotný, Karel

    2015-01-01

    Roč. 63, mimořádné číslo 1 (2015), s. 51-60 ISSN 0015-1831 R&D Projects: GA ČR(CZ) GAP401/10/1164 Institutional support: RVO:67985955 Keywords : Inner Consciousness * Kinesthesis * Pure I * Self * Body * Lived Experience Subject RIV: AA - Philosophy ; Religion

  18. Hanna-Liina ja Dave Benton laulavad koos armastuslaule / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2005-01-01

    Vanemuises L. Bernsteini muusikalis "West Side Story" laulvast Hanna-Liina Võsast, heliplaadist "Premi'ere", kontsertidest koos Dave Bentoniga 4. märtsil Saku mõisas, 6. märtsil Sangaste lossis ja 25. veebr. Ammende villas Pärnus

  19. Dave Bentoni jõulud lauluga / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2004-01-01

    Poplaulja Dave Bentoni arvamusi jõulutraditsioonidest. Jõulutuurist Tallinnas Viimsi kultuurimajas 10. dets.ja Kaarli kirikus 11. dets., Pärnu Eliisabeti kirikus 15. dets., Kuressaare Laurentiuse kirikus 16. dets, Rapla Maarja-Magdaleena kirikus 19. dets., Tartu Peetri kirikus 20. dets., Oleviste kirikus Tallinnas 21. dets., Haapsalu Toomkirikus 22. dets., Jõelähtme kirikus 23. detsembril

  20. 3ot;kbt;sp•.t;kings , Eook Rt;~it;ws

    African Journals Online (AJOL)

    As 'n oud-militere het 'Noggs.' in 1879 die. Anglo-Zoeloeoorlog as 'n spesiale korespon- dent van die Londense Standard beskryf, ter- wyl hy in 1880-1881 iets dergeliks beoog het. Aan sy oorspronklike gedagte om die verloop van die eerste Anglo-Boereoorlog aan Boere- kant waar te neem en te beskryf, kon hy as.

  1. Increased radiosensitivity of a subpopulation ot T-lymphocyte progenitors from patients with Fanconi's anemia

    International Nuclear Information System (INIS)

    Knox, S.J.; Wilson, F.D.; Greenberg, B.R.; Shifrine, M.; Rosenblatt, L.S.; Reeves, J.D.; Misra, H.

    1981-01-01

    In vitro radiation survival of peripheral blood T lymphocytes was studied in 15 clinically normal adults and 4 patients with Fanconi's anemia. Tritiated thymidine incorporation in a whole blood lymphocyte stimulation test (LST) and a newly developed whole blood T-lymphocyte colony assay were used to measure lymphocyte blastogenesis and colony formation in response to phytohemagglutinin (PHA) or concanavalin-A (Con-A) stimulation. Lymphocyte colony formation was found to be consistently more sensitive than the LST for detection of low-level radiation effects using both normal cells and lymphocytes from Fanconi's anemia patients. Lymphocytes from patients with Fanconi's anemia were significantly more sensitive to in vitro x-irradiation than lymphocytes from clinically normal individuals as measured by their ability to divide when stimulated by PHA in the LST (patients, D37 . 198 R; normals, D37 . 309 R, p . 0.057) and colony formation assay (patients, D37 . 53 R; normals, D37 . 109 R, p . 0.016). No significant difference in the radiosensitivity of the Con-A response was observed between the two groups. The PHA-responsive T-lymphocyte subpopulation in Fanconi's anemia patients appears to be intrinsically defective. The nature of this defect, significance in the disease process, and relevancy of these findings to the establishment of radiation protection standards are discussed

  2. Lateral sellar compartment O.T. (cavernous sinus): history, anatomy, terminology.

    Science.gov (United States)

    Parkinson, D

    1998-08-01

    Claudios Galen (119-199 a.d.) dissected lower animals with parasellar carotid retia bathed in venous blood and transposed his findings to human anatomy. Andreas Vesalius (1514-1564) corrected most of Galen's errors but apparently never looked into this small, extradural compartment, nor, apparently, did Winslow (Exposition Anatomique de la Structure du Corps Humain. London: N. Prevast, 1734), who christened it the "cavernous sinus," (CS) presumably thinking that it would resemble the corpora cavernosa of the penis. Multiple surgical explorations, gross dissections, microscopic views, and vascular casts from early fetuses to an 81 year old have been examined and reviewed. The CS is not a dural sinus nor is it cavernous. The compartment is extradural, and the venous structures contained within consist of a greatly variable plexus of extremely thin-walled veins. The name, CS, is a barrier to the understanding of the structure and function of this extradural anatomical jewel box, which contains fat, myelinated and nonmyelinated nerves, arteries, and a plexus of veins. It is proposed that this name be changed, because it is inaccurate and misleading. The replacement should leave no doubt about its meaning. The lateral sellar compartment is descriptive and accurate. The veins within are a parasellar plexus.

  3. The occurrence of pesticides in groundwater under consideration of diffuse inputs ot total herbicides

    International Nuclear Information System (INIS)

    Skark, C.; Zullei-Seibert, N.

    1994-01-01

    In a research project supported by the Environmental protection Agency (Umweltbundesamt) of the FRG we studied the connection between pesticide utilization and pesticide occurrence in groundwater in 58 examples of waterworks. Two thirds of all water sampling points considered were dominated by groundwater and most of these wells were built in porous aquifers. In other sampling points surface water or water which was dominated by artificial recharge of surfacewater of bankfiltration was analysed for pesticides. Independent of the sampling point character 5% of all single substance tests showed the occurrence of pesticides. Atrazine, desethylatrazine and simazine were detected with a frequency exceeding the average occurrence. The herbicides diuron and bromacil could be measured at least with an average frequency, indicating that the application of both substances in water protection areas may cause water quality problems. (orig.) [de

  4. Start-up ettevõtja kapitali kaasamist lihtsustavad äriseadustiku muudatused / Maivi Ots

    Index Scriptorium Estoniae

    Ots, Maivi, 1974-

    2015-01-01

    20. novembril 2014 Vabariigi Valitsuse poolt Riigikogule menetlemiseks saadetud äriseadustiku muutmise seaduse eelnõust, mille kavandatavad muudatused võimaldavad osaühingutel kapitali lihtsamalt kaasata

  5. Royal Policy and the Transfer ot the Consulado under the Old Regime

    Directory of Open Access Journals (Sweden)

    Allan J. KUETHE

    2017-11-01

    Full Text Available The abrupt transfer of the Casa de la Contratación and the Consulado de Cargadores a Indias from Seville to Cádiz in 1717 opened a political struggle between the two cities that would not be completely resolved until the enlightened absolutism of the Marqués de la Ensenada imposed its will. This struggle witnessed old regime politics at both their best and their worst. The present work seeks to analyze the several manifestations of this competition as well as the broader settings in which they occurred. While the new absolutism first appeared through the abad Alberoni in the original transfer and again through its affirmation by the duque de Ripperdá, with the hand of Queen Isabel not far beneath the surface, the traditional culture of consultation and compromise would eventually emerge and permit Seville to retain important powers until much later. Then, in a new era with much different priorities, which were heavily influenced by the coming of the War of the Asiento, royal absolutism as personified by Ensenada and his immediate predecessors would strip Sevilla of its remaining rights and at long last complete the transfer that had begun over twenty-six years before. 

  6. WHY DO THE ACUTE BEHAVIORAL EFFECTS OT TOLUENE IN RATS DEPEND ON THE ROUTE OF EXPOSURE?

    Science.gov (United States)

    Despite evidence suggesting that the acute effects of organic solvents are related to their concentration in the brain, we have observed route-dependent differences in the acute behavioral effects of toluene. Whereas inhaled toluene disrupts the performance of rats on a visual si...

  7. 12 CFR 585.120 - What factors will OTS consider in reviewing my application?

    Science.gov (United States)

    2010-01-01

    ... TREASURY PROHIBITED SERVICE AT SAVINGS AND LOAN HOLDING COMPANIES Exemptions § 585.120 What factors will... the savings and loan holding company; or (ii) Threaten the safety and soundness of any insured depository institution that is controlled by the savings and loan holding company, the interests of its...

  8. 3-Loop massive O(T2F) contributions to the DIS operator matrix element Agg

    International Nuclear Information System (INIS)

    Ablinger, J.; Schneider, C.; Bluemlein, J.; Freitas, A. de; Hasselhuhn, A.; Round, M.; Manteuffel, A. von

    2014-09-01

    Contributions to heavy flavour transition matrix elements in the variable flavour number scheme are considered at 3-loop order. In particular a calculation of the diagrams with two equal masses that contribute to the massive operator matrix element A (3) gg,Q is performed. In the Mellin space result one finds finite nested binomial sums. In x-space these sums correspond to iterated integrals over an alphabet containing also square-root valued letters.

  9. Logický čtverec a otázka existence

    Czech Academy of Sciences Publication Activity Database

    Vlasáková, Marta

    2015-01-01

    Roč. 63, č. 1 (2015), s. 77-93 ISSN 0015-1831 R&D Projects: GA ČR(CZ) GA13-21076S Institutional support: RVO:67985955 Keywords : Aristotelian logic * square of opposition * existential import * existence as a second-order property Subject RIV: AA - Philosophy ; Religion

  10. 78 FR 76721 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    Science.gov (United States)

    2013-12-19

    ... in the preamble, the Board of Directors of the Federal Deposit Insurance Corporation revises part 344...; and (2) If the FDIC-supervised institution is to receive remuneration from the customer or any other source in connection with the transaction, a statement of the source and amount of any remuneration to be...

  11. Portrait of an OT artist: Using Mindfulness to find Life Balance

    Directory of Open Access Journals (Sweden)

    Lydia Royeen

    2016-01-01

    Full Text Available Lynn Davies, a Canadian-based occupational therapist, understands the skill set and practice required to employ a balanced work/play/leisure routine, even for an occupational therapist. Occupational therapists can easily foster this balanced routine for clients; however, they may fall short of adopting this balanced routine in their own lives. Lynn uses art and mindfulness strategies to strive for a meaningful routine. Balancing her work as a therapist and her engagement in art is an ever-evolving orchestra, as she has a passion for both.

  12. Maaelu Eestis 1940.-1950. aastatel ajakirja Pilt ja Sõna materjalide põhjal / Loone Ots

    Index Scriptorium Estoniae

    Ots, Loone, 1965-

    2007-01-01

    Maaelu kujutamisest ajakirja Pilt ja Sõna 1946., 1950. ja 1956. aasta numbrites. Erinevustest varanõukoguliku, tippstalinistliku ja poststalinistliku põllumajanduse käsitluste vahel, propaganda lõimumisest ajakirjas ilmunud materjalidega

  13. Development of a curriculum for OT students Learning about Intervention for Patients with COPD

    DEFF Research Database (Denmark)

    Larsen, Stina Meyer; Petersen, Anne Karin

    Et projekt med kobling af teori og praksis i perioden 2007-2009 med udvikling af konkret undervisningsforløb til ergoterapeutstuderende. Faserne i projektperioden var søgning af litteratur om kroniske lidelser, KOL og ergoterapi, dialog med ergoterapeuter i lokalmiljøet, udarbejdelse af studiefor...

  14. Zhenihh Balzaminov, skrõvajas ot svahh, zanimalsja jogoi / Oleg Peranov

    Index Scriptorium Estoniae

    Peranov, Oleg

    2004-01-01

    Mängufilm Aleksandr Ostrovski teoste alusel "Balsaminovi abiellumine" ("Zhenitba Balzaminova") : stsenarist ja režissöör Konstantin Voinov : Nõukogude Liit 1964. Osavõtjate mälestusi filmi võtetelt

  15. Myths and the evolution ot science | Otu | Sophia: An African Journal ...

    African Journals Online (AJOL)

    The paper used the hermeneutic and analytical methods to x-ray the views of Claude Levi-Straus, Karl Popper, including the extremely complex knowledge of astronomy of the Dogon people of Mali to arrive at the conclusion that myths remain pivotal categories for the development of science especially for developing ...

  16. Ants Paju - philosopher in action / llle Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Ants Paju on olnud Eesti Ülemnõukogu ja Riigikogu liige, Jõgeva linnapea ning aktiivne sportlane. Tema eestvõtmisel on Tallinn-Tartu maantee äärde rajatud Sõpruse park. Lisa: Park of Friendship

  17. Brand positioning strategies : an expiremental test ot two types of benefit differentiation

    OpenAIRE

    Hem, Alexander Farestvedt; Teslo, Per Christian Strand

    2012-01-01

    The purpose of this study is to examine associative- and instrumental benefit differentiation based on secondary associations as part of brand positioning. The field of brand positioning has been subject to extensive research, however, differentiation based on secondary associations and differences between instrumental- and associative benefit differentiation has received less attention. Instrumental benefit differentiation relates to benefits that are linked directly to product performance, ...

  18. A re-examination of symmetry/Group relationships as applied ot the elementary particles

    International Nuclear Information System (INIS)

    Byrd, K.; Cole R.

    1993-01-01

    The purpose of this investigation is to apply Group Theory to the elementary particles. Group Theory is a mathematical discipline used to predict the existence of elementary particles by physicists. Perhaps, the most famous application of Group Theory to the elementary particles was by Murray Gell-Mann in 1964. Gell-Mann used the theory to predict the existence and characteristics of the then undiscovered Omega Minus Particle. Group Theory relies heavily on symmetry relationships and expresses them in terms of geometry. Existence and the characteristics of a logical intuitable, but unobserved member of a group are given by extrapolation of the geometric relationships and characteristics of the known members of the group. In this study, the Delta, Sigma, Chi and Omega baryons are used to illustrate how physicists apply geometry and symmetrical relationships to predict new particles. The author's hypothesis is that by using the D3 crystal symmetry group and Gell-Mann's baryons, three new particles will be predicted. The results of my new symmetry predicts the Omega 2, Omega 3, and Chi 3. However, the Chi 3 does not have characteristics consistent with those of the other known group members

  19. 78 FR 54403 - Removal of Transferred OTS Regulations Regarding Recordkeeping and Confirmation Requirements for...

    Science.gov (United States)

    2013-09-04

    ...\\ The purpose of part 344 was two-fold: (1) To ensure that bank customers purchasing securities received... deposit account to purchase a security or securities, or any prearranged, automatic redemption or sale of..., administrator, guardian, or custodian under the Uniform Gifts to Minors Act; or (2) In a fund consisting solely...

  20. Deniel Kreig : Polutshiv rol Dzheimsa Bonda, ja napilsja ot stshastja! / Daniel Craig ; interv. Stass Tõrkin

    Index Scriptorium Estoniae

    Craig, Daniel

    2006-01-01

    Ajakirjanikud Londonis uue Bondi-filmi "007: Casino Royale" esilinastusel ja pressikonverentsil. Näitleja Daniel Craig räägib endast, oma Bondi karakterist. Lisaks kõigi Bondi osatäitjate lühiandmed "Vse sekretnõje agentõ", kuulsaimad Bondi tüdrukud "7 samõh seksualnõh devushek agenta 007"

  1. Induction o.t labour with intravaginal misoprostol in the second and ...

    African Journals Online (AJOL)

    the discretion of the labour ward staff, oxytocin was used to augment labour. Otherwise, an intravenous drip was not routinely inserted. If the patient was not in labour within 12 hours of receiving the last dose of misoprostol, the treatment was considered a failure. Objective. To confirm the effectiveness of misoprostol as a.

  2. Routine evaluation ot arteriopathies of the lower extremities by digital subtraction angiography

    Energy Technology Data Exchange (ETDEWEB)

    Stacul, F; Pozzi-Mucelli, R; Predonzan, F; Magnaldi, S; Abbona, M; Pozzi-Mucelli, R S; Dalla Palma, L

    1985-11-01

    Intravenous digital subtraction angiography (DSA) was performed in 119 patients with lower extremity ischemia using a 14'' amplifier. Four injections of contrast medium were usually necessary for a complete evaluation of this vascular region. Images of good quality were obtained in most cases; movement artifacts and a faint opacification accounted for any poor results, which occured mainly under the knee. The technique of pixel shifting turned out to be very useful to remove movement artifacts. The 'measuring field' allowed us to minimize the problem of the inhomogeneous saturation of the amplifier. In 8% of the cases an intra-arterial DSA has been performed after an unsatisfactory intravenous examination. Conventional angiography appears to be no longer necessary.

  3. Ursa Major: ot losya do medvedya %t Ursa Major: from elk to bear

    Science.gov (United States)

    Lushnikova, A. V.

    In the article material from various cultural and linguistic sources (Indo-European - Slavic, Indo-Iranian; Uralo-Altaic, Tungus, Ancient Egyptian, Babylonian) is used in order to trace up the chronology of the designation of Ursa Majopr, a constellation which has been playing an important role for people different regions since ancient times. It was used for observing of the visible yearly motion of the Sun, for working out seasonal changes; being a circumpolar and non-hiding behind the horizon it has been perceived as a symbol of immortality, its peculiar positional change during a year lay down in plot of the Uralo-Siberian myths about a cosmic hunt for the Elk, myths about deluge. Data from Uralo-Siberian mythology are analyzed. Designations of Ursa Major in the form of a horned hoofed animal such as elk, deer, cow (Uralo-Altaic, Tungus, Slavic, Indo-Iranian languages; Ancient Greece, Crete, Ancient Egypt) and connected with it (or derived from it) denominations and images of "enclosed space" - "vehicle for travelling and carrying goods" (a wagon, a boat) - "instrument for hunting-fishing, a ritual thing" - "household construction" are taken in consideration. The conclusion is made that the transition of the Ursa Major designation from elk to bear could follow the general tendency to shift from so-called matriarchy to patriarchy, to substitute female deities with male ones, which was reflected "in the rise" of the predatory animal cults (not earlier than II mil. B.C.). To prove this, lexical examples of resemblance and coincidences in designation of homed hoofed (elk, deer) and predatory (bear, wolf) animals should be analyzed. Such a goal-directed investigation of the chronology of Ursa Major designations has never been carried out.

  4. Mõistetüübi ja informatsiooni organiseerimise viisi seotus probleemlahenduse edukusega / Aivar Ots

    Index Scriptorium Estoniae

    Ots, Aivar

    2003-01-01

    Võimalike seoste analüüs erinevate mõistetüüpide kasutamise eelistamise ja informatsiooni organiseerimise viisi vahel. KVÜÕA-s välja töötatud õpikatse ja selle tulemuste tutvustamine. Graafikud

  5. OT2_amoor_4: A census of debris disks in nearby young moving groups with Herschel.

    Science.gov (United States)

    Moór, A.

    2011-09-01

    Nearly all young stars harbour circumstellar disks, that serve as the reservoir for mass accretion onto the star, and later become the birthplace of planetary systems. After the disappearance of the gas component from the disk a dusty debris disk is formed that is believed to mark the location of the planetesimal belt as well. For outlining the evolution of such debris disks traditionally open clusters and field stars were studied, however we argue that the recently discovered young moving groups are more suitable objects for such analyses, due to their proximity and good coverage of the first 50 Myr period of the planetary system evolution. In this proposal we request 70/160 um Herschel/PACS photometric observations for so-far unobserved moving group members. These observations will provide a complete coverage of all known members within 80 pc of five nearby young moving groups (beta Pic Moving Group, Tucana-Horologium, Carina, Columba, and Argus), in the A to K spectral range. Based on the new observations we will identify new debris disks, characterize the disk population within individual moving groups, and study disk evolution by comparing the groups of different ages. The results will be used to verify predictions of the self-stirring model of the evolution of planetesimal disks. We will also compare the properties of debris disks in groups of the same age, looking for additional 'environmental' parameters that affect disk structure over a whole moving group. Our study will be a significant contribution to the census of debris disks in young moving groups, increasing the number of observed sources by a factor of 1.5. Since Spitzer could perform only a limited census and the so-far approved Herschel programs added very few additional moving group obervations, our programme is expected to have a high legacy value.

  6. Report on the Audit ot the Acquisition of the Tacit Rainbow Anti-Radiation Missile System

    Science.gov (United States)

    1991-06-24

    This is our final report on the audit of the Tacit Rainbow Anti-Radiation Missile System (Tacit Rainbow) for your information and use. We performed... the audit from March through December 1990. The audit objective was to evaluate the acquisition management of the air-launched Tacit Rainbow system to...contains no recommendations because DoD took action to cancel the Tacit Rainbow system in FY 1992. We are bringing the issues identified during the audit to

  7. High-power extended cavity laser optimized for optical pumping ot Rb

    Czech Academy of Sciences Publication Activity Database

    Buchta, Zdeněk; Číp, Ondřej; Lazar, Josef

    2007-01-01

    Roč. 18, č. 9 (2007), N77-N80 ISSN 0957-0233 R&D Pro jects: GA ČR GA102/04/2109; GA MŠk(CZ) LC06007; GA AV ČR IAA200650504; GA AV ČR IAA1065303 Institutional research plan: CEZ:AV0Z20650511 Keywords : laser diode * emission linewidth * diffraction grating * optical pumping * spectroscopy Subject RIV: BH - Optics, Masers, Lasers Impact factor: 1.297, year: 2007

  8. Kas Eesti muusikaõpetus vaevleb rahapuuduses? / Elin Ots ; interv. Kristel Kossar

    Index Scriptorium Estoniae

    Ots, Elin

    2006-01-01

    Vestlusringis arutavad muusikaõpetajad ja haridusametnikud millised probleemid musikaharidust kimbutavad ja milliseid reforme see vajab. 17. novembril toimunud Eesti Muusikaõpetajate Liidu koolimuusika-alase konverentsi kaks väliskülalist prof. Franz Niermann ja Soili Perkiö avaldavad oma arvamust

  9. Portrait of an OT artist: Using Mindfulness to find Life Balance

    OpenAIRE

    Lydia Royeen

    2016-01-01

    Lynn Davies, a Canadian-based occupational therapist, understands the skill set and practice required to employ a balanced work/play/leisure routine, even for an occupational therapist. Occupational therapists can easily foster this balanced routine for clients; however, they may fall short of adopting this balanced routine in their own lives. Lynn uses art and mindfulness strategies to strive for a meaningful routine. Balancing her work as a therapist and her engagement in art is an ever-evo...

  10. ICT and OTs: a model of information and communication technology acceptance and utilisation by occupational therapists.

    Science.gov (United States)

    Schaper, Louise K; Pervan, Graham P

    2007-06-01

    There is evidence to suggest that health professionals are reluctant to accept and utilise information and communication technologies (ICT) and concern is growing within health informatics research that this is contributing to the lag in adoption and utilisation of ICT across the health sector. Technology acceptance research within the field of information systems has been limited in its application to health and there is a concurrent need to develop and gain empirical support for models of technology acceptance within health and to examine acceptance and utilisation issues amongst health professionals to improve the success of information system implementation in this arena. This paper outlines a project that examines ICT acceptance and utilisation by Australian occupational therapists. It describes the theoretical basis behind the development of a research model and the methodology being employed to empirically validate the model using substantial quantitative, qualitative and longitudinal data. Preliminary results from Phase II of the study are presented. The theoretical significance of this work is that it uses a thoroughly constructed research model, with potentially the largest sample size ever tested, to extend technology acceptance research into the health sector.

  11. Baltijskaja Evropa: ot idei k strategii [From the idea to the strategy of Baltic Europe

    Directory of Open Access Journals (Sweden)

    Palmowski Tadeusz

    2009-01-01

    Full Text Available This article focuses on the historic prerequisites and forms of international cooperation in the Baltic region (“Baltic cooperation”. According to the author, Baltic Europe is being formed as a single administrative, economic, cultural and infrastructural area, which could become a new economic and cultural center of Europe. Special emphasis is given to policies and strategies of the EU in the Baltic Sea region.

  12. Scho d chara ots of ott) infe acteriz cocoy ected w zation yam

    African Journals Online (AJOL)

    SAM

    defen eins extracted fr. 1054 (Wi) and blotted on PVD specific for PR-3 extracted from th ose of their res s following SDS ased resistan. ,3-glucanase activity was ction. Я-1,3- essed in RO1 w accumulati. The low leve e tolerant c me may not h defense agai itinase in the yam at 8 dp nse-related in. Nyoche rom the roots of.

  13. OT1_ipascucc_1: Understanding the Origin of Transition Disks via Disk Mass Measurements

    Science.gov (United States)

    Pascucci, I.

    2010-07-01

    Transition disks are a distinguished group of few Myr-old systems caught in the phase of dispersing their inner dust disk. Three different processes have been proposed to explain this inside-out clearing: grain growth, photoevaporation driven by the central star, and dynamical clearing by a forming giant planet. Which of these processes lead to a transition disk? Distinguishing between them requires the combined knowledge of stellar accretion rates and disk masses. We propose here to use 43.8 hours of PACS spectroscopy to detect the [OI] 63 micron emission line from a sample of 21 well-known transition disks with measured mass accretion rates. We will use this line, in combination with ancillary CO millimeter lines, to measure their gas disk mass. Because gas dominates the mass of protoplanetary disks our approach and choice of lines will enable us to trace the bulk of the disk mass that resides beyond tens of AU from young stars. Our program will quadruple the number of transition disks currently observed with Herschel in this setting and for which disk masses can be measured. We will then place the transition and the ~100 classical/non-transition disks of similar age (from the Herschel KP "Gas in Protoplanetary Systems") in the mass accretion rate-disk mass diagram with two main goals: 1) reveal which gaps have been created by grain growth, photoevaporation, or giant planet formation and 2) from the statistics, determine the main disk dispersal mechanism leading to a transition disk.

  14. The Transition from Spacecraft Development Ot Flight Operation: Human Factor Considerations

    Science.gov (United States)

    Basilio, Ralph R.

    2000-01-01

    In the field of aeronautics and astronautics, a paradigm shift has been witnessed by those in academia, research and development, and private industry. Long development life cycles and the budgets to support such programs and projects has given way to aggressive task schedules and leaner resources to draw from all the while challenging assigned individuals to create and produce improved products of processes. however, this "faster, better, cheaper" concept cannot merely be applied to the design, development, and test of complex systems such as earth-orbiting of interplanetary robotic spacecraft. Full advantage is not possible without due consideration and application to mission operations planning and flight operations, Equally as important as the flight system, the mission operations system consisting of qualified personnel, ground hardware and software tools, and verified and validated operational processes, should also be regarded as a complex system requiring personnel to draw upon formal education, training, related experiences, and heuristic reasoning in engineering an effective and efficient system. Unquestionably, qualified personnel are the most important elements of a mission operations system. This paper examines the experiences of the Deep Space I Project, the first in a series of new technology in-flight validation missions sponsored by the United States National Aeronautics and Space Administration (NASA), specifically, in developing a subsystems analysis and technology validation team comprised of former spacecraft development personnel. Human factor considerations are investigated from initial concept/vision formulation; through operational process development; personnel test and training; to initial uplink product development and test support. Emphasis has been placed on challenges and applied or recommended solutions, so as to provide opportunities for future programs and projects to address and disposition potential issues and concerns as early as possible to reap the benefits associated with learning from other's past experiences.

  15. A parametric study ot protease production in batch and fed-batch cultures of Bacillus firmus.

    Science.gov (United States)

    Moon, S H; Parulekar, S J

    1991-03-05

    Proteolytic enzymes produced by Bacillus species find a wide variety of applications in brewing, detergent, food, and leather industries. Owing to significant differences normally observed in culture conditions promoting cell growth and those promoting production of metabolites such as enzymes, for increased efficacy of bioreactor operations it is essential to identify these sets of conditions (including medium formulation). This study is focused on formulation of a semidefined medium that substantially enhances synthesis and secretion of an alkaline protease in batch cultures of Bacillus firmus NRS 783, a known superior producer of this enzyme. The series of experiments conducted to identify culture conditions that lead to improved protease production also enables investigation of the regulatory effects of important culture parameters including pH, dissolved oxygen, and concentrations of nitrogen and phosphorous sources and yeast extract in the medium on cell growth, synthesis and secretion of protease, and production of two major nonbiomass products, viz., acetic acid and ethanol. Cell growth and formation of the three nonbiomass products are hampered significantly under nitrogen, phosphorous, or oxygen limitation, with the cells being unable to grow in an oxygen-free environment. Improvement in protease production is achieved with respect to each culture parameter, leading in the process to 80% enhancement in protease activity over that attained using media reported in the literature. Results of a few fed-batch experiments with constant feed rate, conducted to examine possible enhancement in protease production and to further investigate repression of protease synthesis by excess of the principal carbon and nitrogen sources, are also discussed. The detailed investigation of stimulatory and repressory effects of simple and complex nutrients on protease production and metabolism of Bacillus firmus conducted in this study will provide useful guidelines for design of bioreactors for production of protease and bulk chemicals by this bacterium.

  16. Ot Karla Poppera do Karla Rouva i obratno / George Soros ; tõlk. Nikolai Zhdanovitsh

    Index Scriptorium Estoniae

    Soros, George, 1930-

    2007-01-01

    USA on endiselt demokraatlik riik, kus juhindutakse põhiseadusest ja seaduse ülimuslikkuse printsiibist ning kus valitseb massiteabevahendite pluralism. Samas on ka ärevaid märke, mis viitavad totalitaalse režiimi propagandameetoditele

  17. Theoretical analysis of nuclear reactors (Phase I), I-V, Part III, Reactor poisoning; Razrada metoda teorijske analize nuklearnih reaktora (I faza) I-V, III Deo, Zatrovanje reaktora, I faza

    Energy Technology Data Exchange (ETDEWEB)

    Pop-Jordanov, J [Institute of Nuclear Sciences Boris Kidric, Vinca, Beograd (Serbia and Montenegro)

    1962-07-15

    Method was developed for calculation of Xe{sup 135} static effect and kinetic effects of Xe{sup 135} and Sm{sup 149} with separate treatment of iodine effect and influence of reactor poisoning during power increase. Mentioned effects are treated first for uranium fuel and then the basic formulae were generalized for a mixture of fissile material. The annex contains a table with data needed for calculations and the Xe{sup 135} microscopic capture cross section dependent on temperature. Razradjen je metod proracuna statickog efekta Xe{sup 135} zatim kinetickog efekta Xe{sup 135} i Sm{sup 149} sa posebnim tretiranjem jodne jame i promene zatrovanja pri prelazu sa jedne snage na drugu. Navedeni efekti su tretirani prvo za uransko gorivo, a zatim su glavni obrasci uopsteni za smesu fisibilnih materijala. U prilogu su dati u vidu tabele, podaci potrebni za proracun i grafik zavisnosti mikroskopskog preseka zahvata Xe{sup 135} od temperature.

  18. A radiation condition in some regions with more pronounced effect of the Chernobyl accident. Otnosno radiatsionnoto systoyanie v nyakoi rajoni s po-izrazeno vliyanie ot avariyata v Chernobil i ot AETS 'Kozloduj'

    Energy Technology Data Exchange (ETDEWEB)

    Ivanov, I V; Ivanov, I M

    1993-01-01

    The radioecological condition of the Devin region situated in the Rodopes mountain (Bulgaria) has been investigated for the period October 1992 - March 1993. It is believed that the Rodopes were more significantly affected by the Chernobyl accident in comparison with other regions of Bulgaria. Some regions near Kozloduy NPP have been chosen for comparing, for which there are more detailed investigations of the anthropogenic radiation effects. Analysis of the background radiation is made, specific soil and water samples are tested. The alterations in the radiation conditions of the Devin region are analysed. Some conclusions and predictions for the trends in further alterations of the background radiation are made. As a result a draft regional program for environment protection reclamation is prepared. (V.K.).

  19. Kuppelkasvuhoonete disainer üllatab omapärase kunstnikukäega / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2015-01-01

    Kanadas sündinud ja Pärnumaal Lindil elav eestlane Robert Mart Sermat ehitab erilisi kuppelkasvuhooneid ja teeb veel originaalsemat kunsti, mida sai näha näitusel „Heavy Metal” Endla teatri Sammassaalis 27. märtsist kuni 19. aprillini

  20. The first N-terminal unprotected (Gly-Aib)n peptide: H-Gly-Aib-Gly-Aib-OtBu.

    Science.gov (United States)

    Gessmann, Renate; Brückner, Hans; Petratos, Kyriacos

    2015-12-01

    Glycine (Gly) is incorporated in roughly half of all known peptaibiotic (nonribosomally biosynthesized antibiotic peptides of fungal origin) sequences and is the residue with the greatest conformational flexibility. The conformational space of Aib (α-aminoisobutyric acid) is severely restricted by the second methyl group attached to the Cα atom. Most of the crystal structures containing Aib are N-terminal protected. Deprotection of the N- or C-terminus of peptides may alter the hydrogen-bonding scheme and/or the structure and may facilitate crystallization. The structure reported here for glycyl-α-aminoisobutyrylglycyl-α-aminoisobutyric acid tert-butyl ester, C16H30N4O5, describes the first N-terminal-unprotected (Gly-Aib)n peptide. The achiral peptide could form an intramolecular hydrogen bond between the C=O group of Gly1 and the N-H group of Aib4. This hydrogen bond is found in all tetrapeptides and N-terminal-protected tripeptides containing Aib, apart from one exception. In the present work, this hydrogen bond is not observed (N...O = 5.88 Å). Instead, every molecule is hydrogen bonded to six other symmetry-related molecules with a total of eight hydrogen bonds per molecule. The backbone conformation starts in the right-handed helical region (and the left-handed helical region for the inverted molecule) and reverses the screw sense in the last two residues.

  1. OT1_ebergin_5: A Systematic Survery of the Water D to H Ratio in Hot Molecular Cores

    Science.gov (United States)

    Bergin, E.

    2010-07-01

    The D/H ratio of water and the enrichment of HDO relative to H2O in comets, oceans, and interstellar water vapor, has been posited as one of the primary links between chemistry in the cold (T = 10-20 K) dense interstellar medium (ISM) and chemistry in the Solar Nebula. However, there are only ~10 measurements of HDO/H2O, even in hot (T > 100 K) molecular cores, which have the most favorable chemistry (due to fossil evaporation of D-enriched ices) and excitation. In addition the existing measurements have a wide range of uncertainty, making it impossible to discern the presence of source-to-source variations, which could hint at the origin of deuterium enrichments in the dense ISM. We propose here to change this statistic with a systematic survey of HDO and H2O in a sample of 20 hot molecular cores spanning a two order of magnitude range in mass and luminosity. This will increase the number of known water D/H ratios by ~200%. This program is unique in scope for Herschel and requires the uniformity in calibration and high spectral resolution offered by the HIFI instrument. With the stability of HIFI we will be able to derive D/H ratios with significantly less uncertainty. Our observations will be combined with theoretical chemical models to explore the statistics offered by this sample. By looking at a large number of objects with a range of conditions we aim to unlock the secrets of water deuteration in the interstellar space.

  2. The jubilee year of the Estonian protocol was filled with extraordinary events / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2006-01-01

    Eesti välisministeeriumi protokolliosakonna peadirektor Tiia Miller räägib organisatsioonilisest tööst tseremooniate ja riiklike visiitide korraldamisel, sealhulgas USA presidendi George W. Bushi ja Suurbritannia kuninganna Elizabeth II vastuvõtmisest. Juuresolevatel fotodel president Toomas Hendrik Ilves kõrgeid külalisi vastu võtmas

  3. Alkylation of gold surface by treatment with C18H37HgOTs and anodic Hg stripping

    Czech Academy of Sciences Publication Activity Database

    Mucha, Malgorzata; Kaletová, Eva; Kohutová, Anna; Scholz, F.; Stensrud, Elizabeth; Stibor, Ivan; Pospíšil, Lubomír; Wrochem von, F.; Michl, Josef

    2013-01-01

    Roč. 135, č. 15 (2013), s. 5669-5677 ISSN 0002-7863 R&D Projects: GA ČR GA203/07/1619; GA ČR GA203/09/0705 EU Projects: European Commission(XE) 213382 - FUNMOL; European Commission(XE) 227756 - DIPOLAR ROTOR ARRAY Institutional support: RVO:61388963 ; RVO:61388955 Keywords : self-assembled monolayers * altitudinal molecular rotors * AU(111) * mercury Subject RIV: CC - Organic Chemistry Impact factor: 11.444, year: 2013

  4. Modeling the Operation of a Platoon of Amphibious Vehicles for Support of Operational Test and Evaluation (OT&E)

    National Research Council Canada - National Science Library

    Gaver, Donald

    2001-01-01

    ...) of the Marine Corps' prospective Advanced Amphibious Assault Vehicle (AAAV). The model's emphasis is on suitability issues such as Operational Availability in an on-land (after ocean transit) mission region...

  5. 75 FR 63107 - Alternatives to the Use of External Credit Ratings in the Regulations of the OTS

    Science.gov (United States)

    2010-10-14

    ..., savings associations must consider the interest rate, credit, liquidity, price and other risks presented... subject only to moderate credit risk, and for whom expectations of default risk over the term of the... securities activities based on the levels and types of risks in its portfolio. As with the credit quality...

  6. Solar and artificial radiation: health effects and protective measures -- position statement and overview. (RSU 118/OT0799)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-08-16

    Sunburn is the skin's visible reaction to acute overexposure to ultraviolet radiation (UVR). It is estimated that in any given year there are about 3,150 new cases of malignant melanoma, the deadliest kind of skin cancer, and 64,000 new cases of non-melanoma skin cancers in Canada. Between 1986 and 1995 the age-standardized mortality of malignant melanoma increased by an annual average of 2.7 per cent among men and 1.7 per cent among women, the largest increase in mortality of all cancers in men and the second largest among women. This report provides a brief overview of the main characteristics, sources and health effects of ultraviolet radiation, along with a description of general protective measures and recommendations for specific settings. The expectation is that the document will help to promote sound UVR exposure reduction practices, and by so doing, help to reduce the negative health effects of overexposure to UVR among Canadians. The recommended protective measures include minimizing sun exposure (including exposure to sunlamps which are not considered a safe way to get a tan); seeking shade, especially from 11.00 AM to 4.00 PM; covering up; using a sunscreen with SPF 15 or higher that has both UV and UVB protection; and using lip and eye protection. Practising regular skin self-examination is also recommended.

  7. Crystal structure of product-bound complex of UDP-N-acetyl-D-mannosamine dehydrogenase from Pyrococcus horikoshii OT3

    Energy Technology Data Exchange (ETDEWEB)

    Pampa, K.J., E-mail: sagarikakj@gmail.com [Department of Studies in Microbiology, University of Mysore, Mysore 570 006 (India); Lokanath, N.K. [Department of Studies in Physics, University of Mysore, Mysore 570 006 (India); Girish, T.U. [Department of General Surgery, JSS Medical College and Hospital, JSS University, Mysore 570 015 (India); Kunishima, N. [Advanced Protein Crystallography Research Group, RIKEN SPring-8 Center, Harima Institute, Hyogo 679-5148 (Japan); Rai, V.R. [Department of Studies in Microbiology, University of Mysore, Mysore 570 006 (India)

    2014-10-24

    Highlights: • Determined the structure of UDP-D-ManNAcADH to a resolution of 1.55 Å. • First complex structure of PhUDP-D-ManNAcADH with UDP-D-ManMAcA. • The monomeric structure consists of three distinct domains. • Cys258 acting as catalytic nucleophilic and Lys204 acts as acid/base catalyst. • Oligomeric state plays an important role for the catalytic function. - Abstract: UDP-N-acetyl-D-mannosamine dehydrogenase (UDP-D-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-D-mannosamine (UDP-D-ManNAc) to Uridine-diphospho-N-acetyl-D-mannosaminuronic acid (UDP-D-ManNAcA) through twofold oxidation of NAD{sup +}. In order to reveal the structural features of the Pyrococcus horikoshii UDP-D-ManNAcADH, we have determined the crystal structure of the product-bound enzyme by X-ray diffraction to resolution of 1.55 Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-D-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed.

  8. Quality of life of nursing-home residents with dementia subject ot surveillance technology versus physical restraints: an explorative study

    NARCIS (Netherlands)

    te Boekhorst, S.; Depla, M.F.I.A.; Francke, A.L.; Twisk, J.W.R.; Zwijsen, S.A.; Hertogh, C.M.P.M.

    2013-01-01

    Objective As physical restraints should only be used in exceptional cases, there is an urgent need for alternatives to restraint use. Surveillance technology could be such an alternative. This study explored whether nursing-home residents with dementia subjected to surveillance technology had better

  9. Multilocus phylogenetic analysis of true morels (Morchella) reveals high levels of endemics in Turkey relative ot other regions of Europe

    Science.gov (United States)

    The present study was conducted to better understand how the phylogenetic diversity of true morels (Morchella) in Turkey compares with species found in other regions of the world. The current research builds on our recently published survey of 10 Turkish provinces and another of the world in which D...

  10. Od lovců k pastevcům: otázka neolitizace severovýchodní Afriky

    Czech Academy of Sciences Publication Activity Database

    Suková, L.; Varadzin, Ladislav

    2013-01-01

    Roč. 15, č. 1 (2013), s. 25-31 ISSN 1213-1628 Institutional support: RVO:67985912 Keywords : Sudan * archaeology * Mesolithic * Neolithic * transition Subject RIV: AC - Archeology, Anthropology, Ethnology

  11. ICT & OTs: a model of information and communications technology acceptance and utilisation by occupational therapists (part 2).

    Science.gov (United States)

    Schaper, Louise; Pervan, Graham

    2007-01-01

    The research reported in this paper describes the development, empirical validation and analysis of a model of technology acceptance by Australian occupational therapists. The study described involved the collection of quantitative data through a national survey. The theoretical significance of this work is that it uses a thoroughly constructed research model, with one of the largest sample sizes ever tested (n=1605), to extend technology acceptance research into the health sector. Results provide strong support for the model. This work reveals the complexity of the constructs and relationships that influence technology acceptance and highlights the need to include sociotechnical and system issues in studies of technology acceptance in healthcare to improve information system implementation success in this arena. The results of this study have practical and theoretical implications for health informaticians and researchers in the field of health informatics and information systems, tertiary educators, Commonwealth and State Governments and the allied health professions.

  12. A inesperada descoberta de Otávio Ianni sobre preconceito contra descendentes de imigrantes poloneses em Curitiba

    Directory of Open Access Journals (Sweden)

    Márcio de Oliveira

    2015-12-01

    Full Text Available Resumo Após a pesquisa da Unesco sobre relações raciais no Brasil, Florestan Fernandes organizou e liderou uma jovem equipe para tratar do mesmo tema. A preferência recaiu então sobre os estados da Região Sul do Brasil, que não tinham feito parte da pesquisa original. Escolhidos por Florestan Fernandes, Fernando Henrique Cardoso, Roberto Jardim Moreira e Octávio Ianni fizeram parte dessa equipe. Na distribuição dos estados, coube a Ianni o Paraná e Santa Catarina, esse último conjuntamente com Fernando Henrique. Embora o objetivo da pesquisa fosse demonstrar a existência de preconceito nas relações raciais naqueles estados, Ianni ficou surpreso em descobrir também um novo preconceito, dessa feita contra imigrantes poloneses e seus descendentes, na cidade de Curitiba, capital do Paraná. Ianni investigou inicialmente a questão e publicou alguns artigos a respeito, nos quais tentou explicar o inesperado preconceito. No intuito de dar continuidade e investigar mais a fundo o fenômeno, elaborou e publicou um projeto de pesquisa sobre o tema que, contudo, nunca veio à luz.

  13. Informovanost dospívajících v otázce HIV/AIDS

    OpenAIRE

    SOMPEKOVÁ, Zuzana

    2008-01-01

    Summary My bachelor work "The Knowing of Adolescents about HIV/AIDS" wants to find out how our adolescents are informed about HIV/AIDS and protection against sexual diseases, how they behave sexually, if they observe rules of safe sex and what they know about handling with potentially contaminated hypos. The theoretical part considers the role of family in sexual education and the role of parents in relation to sexual education. The next question is when and how to start with such education w...

  14. Projekt nastolující otázky : Dolf Seilacher a výstava Fossil Art. [Rozhovor

    Czech Academy of Sciences Publication Activity Database

    Mikuláš, Radek; Seilacher, D. (A.)

    2008-01-01

    Roč. 4, č. 39 (2008), s. 8-8 ISSN 1801-4542. [Fossil Art. Krakow, 01.09.2008-01.11.2008] Institutional research plan: CEZ:AV0Z30130516 Keywords : fossils exhibition * Fossil Art, Krakow * science and art Subject RIV: DB - Geology ; Mineralogy

  15. K otázce etnické identity Rusínů v České republice

    Czech Academy of Sciences Publication Activity Database

    Sulitka, Andrej

    2016-01-01

    Roč. 103, č. 3 (2016), s. 451-471 ISSN 0009-0794 Institutional support: RVO:68378076 Keywords : Ruthenian national minority in the Czech Republic * minoritarian associations in Prague * Ruthenian associations * minoritarian activities of the Ruthenians * self-identification of Ruthenians against Ukrainians * sources of Ruthenian identity Subject RIV: AC - Archeology, Anthropology, Ethnology

  16. Avtograf na Teodor Hagiopetrit ot C''rkovnija istoriko-arheologičeski Institut v Sofija, CIAI 949

    Directory of Open Access Journals (Sweden)

    Džurova Aksinija

    2013-01-01

    Full Text Available Subject of this article is the copy of Four Gospels preserved at the Church Institute in Sofia (gr. 949, which was displayed in the Brilliance of Byzantium Exhibition organized during the 22nd International Congress of Byzantine Studies (August 22 - 27, 2011 and which we assumed to have been produced by the hand of one of the most famous scribes at the end of the 13th and the beginning of the 14th century, i.e. Theodore Hagiopetrites. The type of the script employed in the Four Gospels at the Church Institute (CHAI gr. 949 is in the so-called by L. Politis unique ‘Hagiopetrites Style’. Although the manuscript does not contain a colophon, comparison to the manuscripts of Theodore Hagiopetrites known to us and especially to Cod. D. gr. 29 (Olim. Kos. 35 at the Ivan Dujčev Centre - an autograph of the scribe of 1307, as well as to another manuscript from Saint Petersburg, Cod. gr. of ASUSSR, No 10/667 of the 14th century, provides good reasons to assume that the Four Gospels manuscript (CHAI gr. 949 was also produced by Theodore Hagiopetrites. Our certainty was further substantiated after we had studied in situ the Four Gospels from Academician N. P. Likhachev’s archive published by Igor Medvedev in the collection ‘ In Memoriam Ivan Dujčev’ of 1988 which is currently kept under No 10/667 in the Archive of the Leningrad Section of the Institute of History at the Russian Academy of Science. Having compared the illumination and the specifics of motif stylization, as well as the specific colouring, we could assert that the two manuscripts manifest pronounced similarities. Thereby, the 27 manuscripts by T. Hagiopetrites published by R. Nelson should also be supplemented by the Four Gospels at the Church Institute (CHAI gr. 949 in addition to the Apostle Lectionary of 1307, autograph of Theodore Hagiopetrites at the Dujčev Centre, Cod. D. gr. 29 (Olim. Kos. 35, which R. Nelson briefly mentioned in his preface, and the Saint Petersburg Four Gospels, published by I. Medvedev.

  17. Crystal structure of product-bound complex of UDP-N-acetyl-d-mannosamine dehydrogenase from Pyrococcus horikoshii OT3.

    Science.gov (United States)

    Pampa, K J; Lokanath, N K; Girish, T U; Kunishima, N; Rai, V R

    2014-10-24

    UDP-N-acetyl-d-mannosamine dehydrogenase (UDP-d-ManNAcDH) belongs to UDP-glucose/GDP-mannose dehydrogenase family and catalyzes Uridine-diphospho-N-acetyl-d-mannosamine (UDP-d-ManNAc) to Uridine-diphospho-N-acetyl-d-mannosaminuronic acid (UDP-d-ManNAcA) through twofold oxidation of NAD(+). In order to reveal the structural features of the Pyrococcus horikoshii UDP-d-ManNAcADH, we have determined the crystal structure of the product-bound enzyme by X-ray diffraction to resolution of 1.55Å. The protomer folds into three distinct domains; nucleotide binding domain (NBD), substrate binding domain (SBD) and oligomerization domain (OD, involved in the dimerization). The clear electron density of the UDP-d-ManNAcA is observed and the residues binding are identified for the first time. Crystal structures reveal a tight dimeric polymer chains with product-bound in all the structures. The catalytic residues Cys258 and Lys204 are conserved. The Cys258 acts as catalytic nucleophile and Lys204 as acid/base catalyst. The product is directly interacts with residues Arg211, Thr249, Arg244, Gly255, Arg289, Lys319 and Arg398. In addition, the structural parameters responsible for thermostability and oligomerization of the three dimensional structure are analyzed. Copyright © 2014 Elsevier Inc. All rights reserved.

  18. Descartova ontologie mentální representace a otázka Suárezova vlivu

    Czech Academy of Sciences Publication Activity Database

    Palkoska, Jan

    2010-01-01

    Roč. 7, č. 1 (2010), s. 28-48 ISSN 1214-8407 Institutional research plan: CEZ:AV0Z90090514 Keywords : Descartes * Suárez * mental representation * ontology * idea Subject RIV: AA - Philosophy ; Religion

  19. Learning in a Simulation-OT in Heart Surgery and the Challenges of the Scientification of Work

    Science.gov (United States)

    Langemeyer, Ines

    2014-01-01

    Enhancing competency and collaboration has become a salient topic of the professional debate on medical safety issues. The advantages of simulation-based training scenarios for team communication, routines and critical work procedures especially in operation theatres have been vigorously discussed. However, the literature on simulation-based…

  20. Difference in Injury Mode, Dose-Rate Dependence and RBE of 730-Mev Protons, 100-KVp X-Rays and 250-KVp X-Rays; Differences dans le Type de Lesion, l'Importance du Debit de Dose et l'EBR entre les Protons de 730 Mev, les Rayons X de 100 Kv-Crete et les Rayons X de 250 Kv-Crete; Razlichiya kharaktera porazheniya, zavisimosti ot moshchnosti dozy i obeh protonov s ehnergiej 730 mehv i rentgenovskikh luchej s pikovym napryazheniem 100 i 250 kv; Diferencias en la Modalidad de La Lesion, la Relacion con la Intensidad de Dosis y la EBR de los Protones de 730 Mev, y los Rayos X de 100 Kvp Y de 250 Kvp

    Energy Technology Data Exchange (ETDEWEB)

    Sondhaus, C. A.; Wallace, R. W.; Lyman, J. T.; Kase, K. W.; Steward, P. G. [University of California Lawrence Radiation Laboratory Berkeley (United States)

    1964-03-15

    pogibali na 12 -14-j den' v rezul'tate gemopojeticheskih narushenij, prichem obnaruzhena takaja zhe zavisimost' ot moshhnosti dozy. OBJe protonov po sravneniju s rentgenovskimi luchami s pikovym naprjazheniem 250 kv dlja LD{sub 50} k 30-mu dnju ravnjalas' 0,8; OBJe dlja LD{sub 50} k shestomu dnju ravnjalas' 1,2 pri toj zhe moshhnosti dozy 100 rad/min. Predpolagaetsja, chto razlichija v haraktere porazhenija mogu t byt' svjazany s neodinakovym raspredeleniem tkanevoj dozy. Bolee vysokaja, no izmenjajushhajasja OBJe protonov v otnoshenii kishechnoj smerti na shestoj den', ochevidno, javljaetsja projavleniem jeffekta moshhnosti dozy. Obsuzhdaetsja prakticheskoe znachenie faktorov raspredelenija dozy i ee moshhnosti. (author)

  1. VRIJEDNOST KARBOKSITERAPIJE PRI LIJEČENJU KRONIČNE RANE POTKOLJENICE

    OpenAIRE

    KOVAČEVIĆ, JADRANKA; SINOŽIĆ, TAMARA

    2015-01-01

    Karboksiterapija je potporna metoda liječenja kroničnih rana koja se provodi kutanim ili subkutanim ubrizgavanjem medicinskog ugljičnog dioksida (Co2). osnovni princip djelovanja ubrizganog plina Co2 je korekcija tkivne hipoksije temeljem Bohrovog efekta. Djelujući na endotelne faktore rasta potiče neoangiogenezu te stimuliraju ibroblaste na sintezu kolagena što sve zajedno dovodi do boljeg zacjeljivanja rana. Brojna su područja primjene karboksiterapije: od liječenja kroničnih rana, bolesti ...

  2. KARBOKSITERAPIJA – POTPORNA TERAPIJA U LIJEČENJU KRONIČNIH RANA

    OpenAIRE

    SINOŽIĆ, TAMARA; KOVAČEVIĆ, JADRANKA

    2014-01-01

    Karboksiterapija je potporna metoda liječenja kroničnih rana koja se provodi kutanim ili supkutanim ubrizgavanjem medicinskog ugljičnog dioksida (Co2). osnovni princip djelovanja ubrizganog plina Co2 je korekcija tkivne hipoksije temeljem bohrovog efekta. Djelujući na endotelne faktore rasta potiče neoangiogenezu te stimulirajući fibroblaste na sintezu kolagena što sve zajedno dovodi do boljeg zacjeljivanja rana. brojna su područja primjene karboksiterapije - od liječenja kroničnih rana, bole...

  3. ŽENE U ZNANOSTI: STAKLENI STROP

    OpenAIRE

    PRIJIĆ-SAMARŽIJA, Snježana; AVELINI HOLJEVAC, Ivanka; TURK, Marko

    2009-01-01

    Temeljni cilj članka jest propitivanje postojanja "staklenoga stropa" ili podzastupljenosti žena na rukovodećim položajima u ustanovama znanosti i visokog obrazovanja kakvo je Sveučilište u Rijeci, uključivo i mehanizama koji ga uzrokuju. Prvi dio članka sadrži kratak pregled i analizu empirijskih rezultata istraživanja provedenog na Sveučilištu u Rijeci, koji nedvojbeno upućuju na prisutnost efekta "staklenoga stropa" i, shodno tome, na postojanje prikrivene primarne i s...

  4. Diplomatický protokol a praktické otázky obchodní etikety v USA

    OpenAIRE

    Vojtíšková, Aneta

    2010-01-01

    This thesis focuses on issues of business etiquette and diplomatic protocol of the United States of America. The aim is to provide deeper information in the field of business protocol and social contact. The first chapter describes specific characteristics of American culture and its influences on business negotiation. The second chapter defines selected issues of social and business etiquette. The third chapter is devoted to diplomatic protocol and diplomatic practice of the United States of...

  5. Raně scholastické univerzálie formulace a transformace otázky v 11. století (tzv. vokalismus a Anselm z Canterbury)

    Czech Academy of Sciences Publication Activity Database

    Otisk, Marek

    2012-01-01

    Roč. 9, Supp.1 (2012), s. 32-47 ISSN 1214-8407 Institutional support: RVO:67985955 Keywords : vocalismus * John Roscellinus of Compiègne * Anselm of Canterbury Subject RIV: AA - Philosophy ; Religion

  6. K některým otázkám etnochoreologického studia: tanec, gender a politika

    Czech Academy of Sciences Publication Activity Database

    Stavělová, Daniela

    2010-01-01

    Roč. 20, č. 4 (2010), s. 239-243 ISSN 0862-8351 Institutional research plan: CEZ:AV0Z90580513 Keywords : dance * gender * politics * national movement * identity Subject RIV: AC - Archeology, Anthropology, Ethnology

  7. Regeneración de palmas en plantaciones y bosques nativos en el santuario de fauna y flora Otún, Quimbaya (Risaralda, Colombia

    Directory of Open Access Journals (Sweden)

    Diego Felipe Correa Gómez

    2006-01-01

    undata, Ch. pinnatifron y P. acuminata. En general, las clases plántulas y juveniles 1 contuvieron la mayor cantidad de individuos, con un máximo del 92% de total de individuos de G. undata encontrados en las urapaneras.

  8. Etika vědy a otázky národa v kontextu působení H. G. Schauera

    Czech Academy of Sciences Publication Activity Database

    Drozenová, Wendy; Kučírek, Jiří

    2009-01-01

    Roč. 80, 3-4 (2009), s. 435-450 ISSN 1211-7617 R&D Projects: GA AV ČR(CZ) IAA900090803 Institutional research plan: CEZ:AV0Z90090514 Keywords : Czech traditions of ethics of science * H. G. Schauer * T. G. Masaryk Subject RIV: AA - Philosophy ; Religion

  9. Biblické citáty v apokryfních Otázkách Bartolomějových

    Czech Academy of Sciences Publication Activity Database

    Chromá, Martina

    2016-01-01

    Roč. 85, 3-4 (2016), s. 287-302 ISSN 0037-6736 R&D Projects: GA MK DG16P02H024 Keywords : Questions of Bartholomew * Apocrypha * Old Church Slavonic Subject RIV: AI - Linguistics OBOR OECD: Specific languages

  10. A new determination of cross sections in methane and silane by using an exact method of solution ot the Boltzmann equation

    International Nuclear Information System (INIS)

    Segur, P.; Balaguer, J.P.

    1984-01-01

    We use a modified form of the SN method to solve the Boltzmann equation. We are then able to take into account the strong anisotropy of the distribution function which is known to occur in methane and silane. For a given set of cross-sections, the swarm parameters calculated with this method are very different from these published by previous authors (obtained with the standard two term Legendre expansion of the distribution function). The cross sections which we deduce by comparing experimental and calculated values for drift velocity and transversal diffusion coefficient are very different from these of Pollock or Duncan and Walker. With these two new sets of cross sections we make some calculations in mixtures of methane and silane, methane and argon, silane and argon. We note that our results for swarm parameters (at low E/N) are in good agreement with experimental values when they are available

  11. The marine cyanobacterium Crocosphaera watsonii WH8501 synthesizes the compatible solute trehalose by a laterally acquired OtsAB fusion protein

    NARCIS (Netherlands)

    Pade, N.; Compaoré, J.; Klähn, S.; Stal, L.J.; Hagemann, M.

    2012-01-01

    Compatible solutes are small organic molecules that are involved in the acclimation to various stresses such as temperature and salinity. Marine or moderate halotolerant cyanobacteria accumulate glucosylglycerol, while cyanobacteria with low salt tolerance (freshwater strains) usually accumulate

  12. Dependence of ferrocyanide preparation Bifezh efficiency on age peculiarities of cattle.; Zavisimost` ehffektivnosti ferrotsianidnogo preparata Bifezh ot vozrastnykh osobennostej krupnogo rogatogo skota.

    Energy Technology Data Exchange (ETDEWEB)

    Gashchak, S P; Burov, N I; Arkhipov, N P [Nauchno-Proizvodstvennoe Ob` ` edinenie Pripyat` , Chernobyl (Ukraine)

    1994-12-31

    The aim of the experiment on cattle feeding a ration with high contents of {sup 137} Cs was to estimate an influence of age peculiarities on efficiency of ferrocyanide preparation Bifezh (a food additive). Data testifying to a decrease of the preparation efficiency with the age of calves are obtained. A sum of factors determining this regularity is analyzed.

  13. EPL-i ümarlaud : kõige olulisem on vähi varajane avastamine / Ille Grün-Ots

    Index Scriptorium Estoniae

    Grün-Ots, Ille, 1960-2016

    2007-01-01

    Ümarlaual osalesid TÜ kliinikumi hematoloogia-onkoloogiakliiniku professor Hele Everaus, ravimifirma Roche Eesti OÜ tegevjuht Kadri Mägi, ravifirma GlaxoSmithKline Eesti filiaali juhataja Akshay Mody ja PERH-i keemiaravispetsialist Helis Pokker

  14. Tancova muzika v răkopisite na učitelja Irži Chartăl (1781–1849) ot Stara Paka

    Czech Academy of Sciences Publication Activity Database

    Vejvoda, Zdeněk

    2015-01-01

    Roč. 41, č. 4 (2015), s. 491-512 ISSN 0323-9861 Institutional support: RVO:68378076 Keywords : folk dance * ethnomusicology * ethnochoreology * Jiří Hartl * music collections Subject RIV: AC - Archeology, Anthropology, Ethnology

  15. Subject and authorship of records related to the Organization for Tropical Studies (OTS) in BINABITROP, a comprehensive database about Costa Rican biology.

    Science.gov (United States)

    Monge-Nájera, Julián; Nielsen-Muñoz, Vanessa; Azofeifa-Mora, Ana Beatriz

    2013-06-01

    BINABITROP is a bibliographical database of more than 38000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces) and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011). Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.

  16. Subject and authorship of records related to the Organization for Tropical Studies (OTS in BINABITROP, a comprehensive database about Costa Rican biology

    Directory of Open Access Journals (Sweden)

    Julián Monge-Nájera

    2013-06-01

    Full Text Available BINABITROP is a bibliographical database of more than 38 000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011. Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.

  17. Subject and authorship of records related to the Organization for Tropical Studies (OTS in BINABITROP, a comprehensive database about Costa Rican biology

    Directory of Open Access Journals (Sweden)

    Julián Monge-Nájera

    2013-06-01

    Full Text Available BINABITROP is a bibliographical database of more than 38 000 records about the ecosystems and organisms of Costa Rica. In contrast with commercial databases, such as Web of Knowledge and Scopus, which exclude most of the scientific journals published in tropical countries, BINABITROP is a comprehensive record of knowledge on the tropical ecosystems and organisms of Costa Rica. We analyzed its contents in three sites (La Selva, Palo Verde and Las Cruces and recorded scientific field, taxonomic group and authorship. We found that most records dealt with ecology and systematics, and that most authors published only one article in the study period (1963-2011. Most research was published in four journals: Biotropica, Revista de Biología Tropical/ International Journal of Tropical Biology and Conservation, Zootaxa and Brenesia. This may be the first study of a such a comprehensive database for any case of tropical biology literature.BINABITROP es una base de datos bibliográfica con más de 38 000 registros sobre los ecosistemas y organismos de Costa Rica. En contraste con bases de datos comerciales como Web of Knowledge y Scopus, que excluyen a la mayoría de las revistas científicas publicadas en los países tropicales, BINABITROP registra casi por completo la literatura biológica sobre Costa Rica. Analizamos los registros de La Selva, Palo Verde y Las Cruces. Hallamos que la mayoría de los registros corresponden a estudios sobre ecología y sistemática; que la mayoría de los autores sólo registraron un artículo en el período de estudio (1963-2011 y que la mayoría de la investigación formalmente publicada apareció en cuatro revistas: Biotropica, Revista de Biología Tropical/International Journal of Tropical Biology, Zootaxa y Brenesia. Este parece ser el primer estudio de una base de datos integral sobre literatura de biología tropical.

  18. THOMAS STEARNS ELIOT AND OTTOMAN POETS IDEA UNION OTTOMAN POEM / THOMAS STEARNS ELİOT VE DİVAN SAİRİNİN ORTAK DÜNYASI

    Directory of Open Access Journals (Sweden)

    Dr. Metin HAKVERDİOĞLU

    2009-04-01

    Full Text Available There is an idea and a method union betweenOttoman Poets and Thomas Stearn Eliot. Two differentworld man who contemplating unite a point for humanitythat is genostic human. Ottoman poets support Eliot’sspeech, Eliot says the world that Ottoman poets intimate before century. Our nation who has E. U. idealswill interest us to know these similar points. Becausethere are many thinker people there as us and ancetor.For these people, Eliot is a model both idea father andalso acknowledged man. The writer who was given Nobelreward is saying similar words as Ottoman poets’philosophy. In our duty, we know the past and researchseriously Eliot. It isnt’t possible astonish paralel opinionsabout culture, tradition, religion, philophy, literature.Having been pagan modern world against, it is a supportto Eliot from Ottoman poets before century.

  19. Otázky rukopisu Máchova Máje: K chystané kritické edici básně

    Czech Academy of Sciences Publication Activity Database

    Charypar, Michal

    2017-01-01

    Roč. 65, č. 4 (2017), s. 540-564 ISSN 0009-0468 R&D Projects: GA ČR(CZ) GA16-02328S Institutional support: RVO:68378068 Keywords : textual criticism * Czech romantic poetry * 19th century * Mácha, Karel Hynek * critical hybrid edition * manuscript Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  20. Na jaké otázky odpovídali sociologičtí klasikové? - 1. část

    Czech Academy of Sciences Publication Activity Database

    Simonová, Natalie

    2003-01-01

    Roč. 1, č. 4 (2003), s. 1 ISSN 1214-1720 Institutional research plan: CEZ:AV0Z7028912 Keywords : August Comte * Max Weber * beginning of sociology Subject RIV: AO - Sociology, Demography http://www.socioweb.cz

  1. Dependence of radiation effects in organic materials on absorbed dose rate; Zavisimost` radiatsionnykh ehffektov v organicheskikh materialakh ot moshchn osti pogloshchennoj dozy

    Energy Technology Data Exchange (ETDEWEB)

    B` riksman, B A; Kras` ko, L B; Milinchuk, V K; Sichkar` , V P

    1994-12-31

    Analysis of experimental data on the dose rate effect on the operational properties of organic polymers is conducted. Methods of radiation effects forecasting under utilization of these materials are compared according to the results of the accelerated testing.

  2. [Characteristics of floor litter and soil arthropod community in different types ot subtropical forest in Ailao Mountain of Yunnan, Southwest China].

    Science.gov (United States)

    Yang, Zhao; Yang, Xiao-Dong

    2011-11-01

    By using line transect method, an investigation was conducted on the floor litter and soil arthropod community in a mid mountain wet evergreen broad-leaved forest, a mossy dwarf forest, and a Populus bonatii forest in Ailao Mountain of Yunnan in April (dry and hot season), June (rainy season), and December (dry and cold season), 2005. In both dry and rainy seasons, the existing floor litter mass, C storage, and C/N ratio in the three forests all increased in the order of mossy dwarf forest > P. bonatii forest > evergreen broad-leaved forest, but the N storage had less difference. In the floor litter layer of the forests, Acari and Collembola were the dominant groups of soil arthropod community, while Diptera larvae, Coleoptera, ants, and Homoptera were the common groups. The Sorenson coefficients of soil arthropod community in the three forests were extremely great. No significant differences were observed in the soil arthropod density (ind x m(-2)) in the floor litter layer among the three forests, but the relative density (ind x g(-1)) of soil arthropods was higher in the evergreen broad-leaved forest and P. bonatii forest than in the mossy dwarf forest. In the three forests, the density of soil arthropods was significantly higher in dry season than in rainy season, but the Shannon diversity index had less difference. There were significant positive correlations between the existing floor litter mass and the individual density (ind x m(-2)) and dominant groups of soil arthropod communities in dry and hot season (April), but negative correlations between the existing floor litter mass and the relative density (ind x g(-1)) of soil arthropod communities and Acari in dry and cold season (December). The individual densities of Collembola and Coleoptera also had positive correlations with the N storage of the existing floor litter mass in the three forests. It was considered that the floor litter and the development of soil arthropod community in the litter layer of the subtropical forests in Ailao Mountain had a close relation with the vegetation structure of the forests, and the individual density and the diversity of the soil arthropod community were controlled by the floor litter, whereas the environmental factors such as temperature and moisture in the forests also had obvious effects on the seasonal dynamics of the individual density of the soil arthropods.

  3. Nová metoda kvantifikace otěrových částic UHMWPE v okolí kloubních náhrad

    Czech Academy of Sciences Publication Activity Database

    Pokorný, D.; Šlouf, Miroslav; Dybal, Jiří; Zolotarevova, E.; Veselý, F.; Jahoda, D.; Vavřík, P.; Landor, I.; Entlicher, G.; Sosna, A.

    2009-01-01

    Roč. 76, č. 5 (2009), s. 374-381 ISSN 0001-5415 R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : ultra high-molecular weight polyethylene * total hip arthroplasty * wear Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.628, year: 2009

  4. Metabolomic Analysis of Two Parmotrema Lichens: P. robustum (Degel. Hale and P. andinum (Mull. Arg. Hale Using UHPLC-ESI-OT-MS-MS

    Directory of Open Access Journals (Sweden)

    Alfredo Torres-Benítez

    2017-10-01

    Full Text Available Lichens are symbiotic associations of fungi with microalgae and/or cyanobacteria. Lichens belonging to the Parmeliaceae family comprise 2700 species of lichens, including the Parmotrema genus which is composed of 300 species. The metabolites of this genus include depsides, depsidones, phenolics, polysaccharides, lipids, diphenylethers and dibenzofurans, which are responsible for the biological activities reported including antidiabetic, antihelmintic, anticancer, antioxidant, antibacterial, anti-inflammatory, antimitotic, antitumoral, antifungal, and antioxidant enzyme inhibitory. Due to scarce knowledge of metabolomic profiles of Parmotrema species (P. andinum and P. robustum, a full metabolome study based on ultra-high performance liquid chromatography- diode array detector-electrospray ionization-quadrupole-orbitrap-mass-spectrometry (UHPLC-DAD-ESI-Q-orbitrap MS was performed for a comprehensive characterization of their substances. From the methanolic extracts of these species, a total of 54 metabolites were identified for the first time using this hyphenated technique, including thirty compounds in P. andinum, and thirty-seven in P. robustum. Moreover, two compounds were not identified as known compounds, and could be new structures, according to our data. This report shows that this technique is effective and accurate for rapid chemical identification of lichen substances and the compounds identified could serve as chemotaxonomic markers to differentiate these ruffle lichens.

  5. Vanemliku hoolitsuseta jäänud laste perehoolde korraldamise õiguslikke probleeme : [bakalaureusetöö] / Ingrid Ots-Vaik ; Tartu Ülikool, õigusteaduskond ; juhendaja: Edgar Salumaa

    Index Scriptorium Estoniae

    Ots-Vaik, Ingrid

    2000-01-01

    Lapse õigused ja lastekaitse süsteem Eestis, vanemliku hoolitsuseta jäänud lapse hoolekande korraldamise põhimõtted ja vormid, hoolduspere mõiste, leping lapse hooldamiseks ja kasvatamiseks, Eesti, Venemaa ja Soome hoolduslepingute võrdlev analüüs

  6. Cineradiography of the liquid bolus swallow. A study of the speed ot the bolus and peristaltic wave and of movement of the hyoid bone, larynx, and epiglottis

    International Nuclear Information System (INIS)

    Sundgren, P.

    1991-01-01

    In the evaluation of the dysphagic patient, radiology is crucial as a technique for monitoring morphology and function. In particular, high-speed cineradiography can reveal a variety of pharyngeal dysfunctions. However, in the literature and in practice the difference between normal and abnormal function is not always clear. This monography is based on high-speed cineradiographies of swallowing in 75 non-dysphagic volunteers and in 189 dysphagic patients. The purpose was to study whether differences in bolus volumes, patient position, age and gender had any effects on the following parameters: the speed of the peristaltic wave and apex of the liquid barium bolus, the length of movement and the movement pattern of the hyoid bone and larynx, and epiglottic function. The study disclosed that the speed of the bolus, the anterior-superior movement and net movement of the hyoid bone increased significantly with larger bolus volumes. The position of the individual in relation to gravity significantly influenced the speed of peristalsis. In most of the measured parameters there were no differences between non-dysphagic and dysphagic individuals expect for differences in the intrapersonal variations and in the anterior-superior movement of the hyoid bone. In patients with pharyngeal dysfunction the initial stage of the elevation of the larynx was significantly lower than in patients without dysfunction. The approximation of the thyroid cartilage to the hyoid bone was significantly greater in individuals with normal epiglottic function than in those with epiglottic dysmobility. It is suggested that abnormal speed of peristalsis may be a mild form of dysfunction. Measurements of the aforementioned speed and movements can be done if bolus volume, age and position of the patient, film speed and magnifications factors are known. Hypotheses concerning epiglottic function and central control of swallowing are proposed. (au)

  7. Meediavabaduse reguleerimine - allikakaitse ja vastulause õigus : [teadusmagistritöö] / Kristjan Ots ; Tartu Ülikool, sotsiaalteaduskond ; juhendaja: Halliki Harro-Loit

    Index Scriptorium Estoniae

    Ots, Kristjan, 1976-

    2009-01-01

    Sisaldab ka varem ilmunud artikleid: Ajakirjandusvabadus ja allikakaitse. Juridica, 2005, nr. 8, lk. 571-583 ; Üksikisiku seisund meedia suhtes ning vastulause esitamise õigus. Juridica, 2008, nr. 2, lk. 102-118

  8. Otěr minerálních katalyzátorů ve fluidním zplyňovacím reaktoru

    Czech Academy of Sciences Publication Activity Database

    Hartman, Miloslav; Svoboda, Karel; Pohořelý, Michael; Šyc, Michal

    2012-01-01

    Roč. 106, č. 9 (2012), s. 844-846 ISSN 0009-2770 R&D Projects: GA AV ČR IAA400720701 Grant - others:RFCR(XE) CT2010-00009 Institutional support: RVO:67985858 Keywords : gasification of biomass * catalyst attrition * dolomites and limestones Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 0.453, year: 2012

  9. Õpetaja professionaalse rolli internaliseerimise hindamine õpetajakoolituse esmaõppe üliõpilaste hulgas / Äli Leijen, Katrin Kullasepp, Aivar Ots

    Index Scriptorium Estoniae

    Leijen, Äli, 1979-

    2013-01-01

    Aineõpetaja magistriõppe üliõpilaste seas läbi viidud uurimusest, milles vaadeldakse, kuidas üliõpilased koordineerivad personaalset ja professionaalset mina-positsiooni erialaste ambivalentsete olukordade kontekstis

  10. [Comparison of the cleansing effect of two micromotor-driven endodontic hand pieces. I. Comparison ot the cleansing effect of the two handpieces].

    Science.gov (United States)

    Bartha, K; Rocca, J P

    1993-11-01

    The aim of the study was to assess the cleansing-effect of two endodontic handpieces (Excalibur, W & H; MM 1400 Micro Méga) in root canals that were previously manually prepared, and treated with chlor-(Neomagnol) and citric acid containing solutions. The analyses were performed by scanning electron microscope (SEM). The elimination of the Smear Layer (SL) with Neomagnol was not successful with either of the two handpieces. The cleansing of the Superficial Debris (SD) with Neomagnol activated by MM 1400 was significantly more effective in the apical (p < 0.05) and in the middle (p < 0.01) third of the root-canal, than by Excalibur. In contrast, SL was better eliminated by Excalibur using citric acid, significant differences--when compared with MM 1400--could be seen in the middle third (p < 0.05) of the root-canal. The handpieces seem to have their own specific characteristics: thus MM 1400 was better in eliminating the SD (used with Neomagnol), while Excalibur was superior in eliminating the SL (used with citric acid).

  11. ATTRIBUTION OF CONDUCT TO A STATE-THE SUBJECTIVE ELEMENT OF THE INTERNATIONAL RESPONSIBILITY OT THE STATE FOR INTERNATIONALLY WRONGFUL ACTS

    Directory of Open Access Journals (Sweden)

    FELICIA MAXIM

    2012-05-01

    Full Text Available In order to establish responsibility of states for internationally wrongful act, two elements are identified. First, the conduct in question must be attributable to the State under international law. Secondly, for responsibility to attach to the act of the State, the conduct must constitute a breach of an international legal obligation in force for that State at that time. For particular conduct to be characterized as an internationally wrongful act, it must first be attributable to the State. The State is a real organized entity, a legal person with full authority to act under international law. But to recognize this is not to deny the elementary fact that the State cannot act of itself. States can act only by and through their agents and representatives. In determining what constitutes an organ of a State for the purposes of responsibility, the internal law and practice of each State are of prime importance. The structure of the State and the functions of its organs are not, in general, governed by international law. It is a matter for each State to decide how its administration is to be structured and which functions are to be assumed by government. But while the State remains free to determine its internal structure and functions through its own law and practice, international law has a distinct role. Conduct is thereby attributed to the State as a subject of international law and not as a subject of internal law. The State as a subject of international law is held responsible for the conduct of all the organs, instrumentalities and officials which form part of its organization and act in that capacity, whether or not they have separate legal personality under its internal law.

  12. K otázce tzv. akuzativního se v češtině: pohled (nejen) diachronní

    Czech Academy of Sciences Publication Activity Database

    Pergler, Jiří

    2016-01-01

    Roč. 77, č. 2 (2016), s. 102-122 ISSN 0037-7031 R&D Projects: GA ČR(CZ) GA15-00987S Institutional support: RVO:68378092 Keywords : reflexive form * pronoun * morpheme * particle * categorization * diachrony * grammaticalization * Old Czech Subject RIV: AI - Linguistics Impact factor: 0.625, year: 2016

  13. A contribution ot the continued development of dry magnetic powder method for surface transverse crack testing of continuously casted semi-finished products

    International Nuclear Information System (INIS)

    Jaschke, D.H.

    1982-01-01

    The manifold of complex quality parameters is represented for the further development of a testing system. Selections and criteria for the industrial application and final testing are given and the process conditions are compared with plant possibilities by means of some examples. (orig.) [de

  14. 12 CFR 502.27 - How does OTS determine the risk/complexity component for a savings and loan holding company?

    Science.gov (United States)

    2010-01-01

    ... holding company's financial condition, financial independence of the savings association and other affiliates that are regulated financial entities, operational independence of the savings association and other affiliates that are regulated financial entities, reputational risks raised by affiliation with...

  15. On the nature of anomalies in temperature dependence of the OKh18N1OT steel yield strength after thermal cycling in the low temperature range

    International Nuclear Information System (INIS)

    Medvedev, E.M.; Lavrent'ev, F.F.; Kurmanova, T.N.

    1978-01-01

    Investigated were structural transformations in 0Kh18N10T steel as a result of heating and cooling and of deformation within the range of temperatures between 300 and 77 K, the quantity relationships between the said transformations and the variation of the yield limit with the temperature. The studies were conducted by metallography and mechanical test methods. It was shown that an increase in the number of heating and cooling cycles correlates with a loss in strength of the steel while deformation at 77 K. This anomaly in the temperature relationship of the yield limit is related to the appearance in the course of deformation of α-martensite with a BCC lattice. Deformation at 300 K increases the amount ea of epsilon-martensite, a decrses the effectve size of grain and, in consequence, increases the yield limit. The relationship between the yield limit and the grain size at the temperature of 300 K is described adequately by the Hall-Petch equation

  16. György Lukács, otázky marxistické ortodoxie a český marxismus

    Czech Academy of Sciences Publication Activity Database

    Landa, Ivan

    2017-01-01

    Roč. 1, č. 1 (2017), s. 39-48 ISSN 2570-7485 Institutional support: RVO:67985955 Keywords : Lukács * Dialetical Method * Totality * Kosík * Sochor * Dubský Subject RIV: AA - Philosophy ; Religion OBOR OECD: Philosophy, History and Philosophy of science and technology

  17. Joseph Knabenbauer SJ (1839–1911 a otázka evolučního vzniku člověka

    Directory of Open Access Journals (Sweden)

    Ctirad V. Pospíšil

    2017-08-01

    Full Text Available The paper is a part of the research that focuses on the Catholic theologians and biologists between 1871 and 1910 who accepted Mivart’s thesis of the evolutionary origin of the human body, or who, on the contrary, tended to reject it. The paper presents J. Knabenbauer SJ (1839–1911. In the 1930s, Czech theologian J. Miklik asserted that Knabenauer accepted Mivart’s position. Knabenbauer’s study on evolution is analysed. Already in 1877, Knabenbauer shows, in the first two parts of his work, an openness to the reality of evolutionary origin of species in the fauna and flora. In the third part, he deals with Mivart’s thesis. From the philosophical point of view, Knabenbauer admits the possibility of the creation of human body by way of evolution. From the exegetical point of view, he refuses the reading of Gen 2:7 that considered this verse to be an allusion of the origin of the human body from the animal base. Because of this later view, Miklik’s information is to be considered imprecise. Knnabenbauer’s study contains, though, much relevant information that testifies to the Catholic theology and exegesis of his era.

  18. Právní otázky direct marketingových sdělení v České republice

    OpenAIRE

    Demuthová, Martina

    2014-01-01

    The thesis deals with the issue of direct marketing, its instruments and related legislation. Direct marketing is a form of marketing communication which allows businesses to communicate directly with their customers. Its value in marketing is increasing, as well as spam, which is also defined in this thesis. First explained is the term direct marketing, its advantages and disadvantages, its tools and current role in the industry. Furthermore, a summary of the present legal and ethical regula...

  19. Zaniklé Otěchleby u Velké Bíteše (okr. Žďár nad Sázavou)

    Czech Academy of Sciences Publication Activity Database

    Burešová, M.; Kirchner, Karel; Unger, J.; Roštínský, Pavel; Šedo, Ondrej; Velek, J.

    2013-01-01

    Roč. 65, č. 3 (2013), s. 301-305 ISSN 0323-2581 Institutional support: RVO:68145535 ; RVO:68081758 Keywords : defunct village * Middle Ages * Velká Bíteš Subject RIV: AC - Archeology, Anthropology, Ethnology

  20. K aktuálním otázkám správní vědy

    Czech Academy of Sciences Publication Activity Database

    Grospič, Jiří

    -, č. 1 (2010), s. 23-35 ISSN 0323-0619 Institutional research plan: CEZ:AV0Z70680506 Keywords : public private partnership * administrative law * eGovernment * eGovernance Subject RIV: AG - Legal Sciences

  1. Õpilaste heaolu resilientsus ja mõistestruktuuri areng: erinevused kooliga rahulolu säilitamisel ebameeldivate koolikogemuste ja klassiõpetaja kasvatusstiili taustal / Aivar Ots

    Index Scriptorium Estoniae

    Ots, Aivar

    2014-01-01

    Üle-eestilisest põhikooli õpilaste heaolu uuringust, mille eesmärgiks oli selgitada, kuidas erineb õpilaste võime säilitada koolis kogetavat heaolu, võttes arvesse nende kooliga seotud ebameeldivaid kogemusi ja kognitiivset arengut

  2. K otázce (ne)existence akuzativního se v současné češtině

    Czech Academy of Sciences Publication Activity Database

    Veselý, Luboš

    2013-01-01

    Roč. 5, č. 4 (2013), s. 308-317 ISSN 1803-876X R&D Projects: GA ČR GA13-07138S Institutional support: RVO:68378092 Keywords : reflexive * word form se * accusative case * enclitics * pronoun Subject RIV: AI - Linguistics

  3. O vidu slovesa soustředit se (Příspěvek k otázce jazykové správnosti)

    Czech Academy of Sciences Publication Activity Database

    Veselý, Luboš

    2011-01-01

    Roč. 94, č. 3 (2011), s. 134-141 ISSN 0027-8203 R&D Pro jects: GA ČR GAP406/11/2021 Institutional research plan: CEZ:AV0Z90610518 Keywords : linguistic correctness * prefixation * verbs * verbal aspect Subject RIV: AI - Linguistics

  4. „Čelakovský - ausserordentlich ruhig“. Otázka generací a loajalit v české politice

    Czech Academy of Sciences Publication Activity Database

    Pavlíček, Tomáš W.

    2015-01-01

    Roč. 45, č. 1 (2015), s. 127-137 ISSN 0079-4929. [Formování vědního oboru národních právních dějin ve střední Evropě. Pocta prof. Jaromíru Čelakovskému (1846–1914). Praha, 04.11.2014-06.11.2014] Institutional support: RVO:67985921 Keywords : Čelakovský, Jaromír * political culture Subject RIV: AB - History

  5. Molitva o izbavlenii ot bluda v církevněslovanských rukopisech Trojicko-sergijevské lávry

    Czech Academy of Sciences Publication Activity Database

    Čajka, František

    2013-01-01

    Roč. 82, 1-2 (2013), s. 43-52 ISSN 0037-6736 R&D Projects: GA ČR(CZ) GAP406/12/1790 Institutional support: RVO:68378017 Keywords : Old Church Slavonic * Church Slavonic * prayer * the Trinity Lavra of St. Sergius * manuscripts * Forty Gospel Homilies by Pope Gregory the Great Subject RIV: AI - Linguistics

  6. Uudised : Georg Ots 80. "Pärt in Profile" Londonis. Kaljuste taas esile tõstetud. Paavo Järvi eesti muusikaga La Scalas / Priit Kuusk

    Index Scriptorium Estoniae

    Kuusk, Priit, 1938-

    2000-01-01

    G. Otsa 80. sünniaastapäeva tähistamisest G. Otsa nim. Tallinna Muusikakoolis ئ avati G. Otsa muuseum. 28.-31. märtsini Londonis toimuvast muusikafestivalist "Pärt in Profile", kus tutvustatakse A. Pärdi jt. eesti heliloojate loomingut. T. Kaljuste on Edison Classical Music Awards 2000 nominentide seas koorimuusika kategoorias kahel korral. P. Järvi juhatas 28. veebr. Milano La Scala orkestrit, kavas A. Pärdi "Cantus in memoriam Benjamin Britten", dirigendi tegemistest märtsis

  7. Provencance of the late Proterozoic to early Cambrian metaclastic sediments ot the Sierra de San Luis (Eastern Sierras Pampeanas) and Cordillera Oriental, Argentina

    DEFF Research Database (Denmark)

    Drobe, M.; López de Luchi, M.; Steenken, A.

    2009-01-01

    Provenance studies have been performed utilising major and trace elements, Nd systematics, whole rock Pb-Pb isotopes and zircon U/Pb SHRIMP data on metasedimentary rocks of the Sierra de San Luis (Nogolí Metamorphic Complex, Pringles Metamorphic Complex, Conlara Metamorphic Complex and San Luis...... is depicted for all the complexes using major and trace elements. The Pringles Metamorphic Complex shows indications for crustal recycling, pointing to a bimodal provenance. Major volcanic input has to be rejected due to Th/Sc, Y/Ni and Cr/V ratios for all units. The eNd(540 Ma) data is lower for the San Luis...... Formation and higher for the Conlara Metamorphic Complex, as compared to the other units, in which a good consistency is given. This is similar to the TDM ages, where the metapsammitic samples of the San Luis Formation are slightly older. The spread of data is largest for the Pringles Metamorphic Complex...

  8. Njakoi ot po-novite publikacii na Instituta za Češki nacionalen korpus za perioda 2010-2011 godina

    Czech Academy of Sciences Publication Activity Database

    Uhlířová, L.; Nisheva, Bozhana

    2013-01-01

    Roč. 38, č. 1 (2013), s. 42-51 ISSN 0204-8701 Institutional support: RVO:68378017 Keywords : Institute of the Czech National Corpus * Czech and Bulgarian language of propaganda * totalitarian age Subject RIV: AI - Linguistics

  9. Design, synthesis and biological activity of new neurohypophyseal hormones analogues conformationally restricted in the N-terminal part of the molecule. Highly potent OT receptor antagonists

    Czech Academy of Sciences Publication Activity Database

    Kwiatkowska, A.; Ptach, M.; Borovičková, Lenka; Slaninová, Jiřina; Lammek, B.; Prahl, A.

    2012-01-01

    Roč. 43, č. 2 (2012), s. 617-627 ISSN 0939-4451 Institutional research plan: CEZ:AV0Z40550506 Keywords : oxitocin antagonists * Atosiban * neurohypophyseal hormones analogues * arginine vasopressin (AVP) * antidiuretic hormone * binding affinity Subject RIV: CE - Biochemistry Impact factor: 3.914, year: 2012

  10. Horké vlny v měnícím se klimatu: otázky zůstávají

    Czech Academy of Sciences Publication Activity Database

    Kyselý, Jan; Pecho, Jozef

    2012-01-01

    Roč. 91, - (2012), s. 28-34 ISSN 0042-4544 Institutional support: RVO:68378289 Keywords : heat waves * climate change * global warming * European heat waves 2003 * Czech Republic. Subject RIV: DG - Athmosphere Sciences, Meteorology http://www.vesmir.cz/obor/klimatologie

  11. Maret Maripuu : HIV-haigete raviks jätkub raha ka järgmisel aastal / Maret Maripuu ; interv. Ille Grün-Ots

    Index Scriptorium Estoniae

    Maripuu, Maret, 1974-

    2008-01-01

    Sotsiaalministri Maret Maripuu sõnul leiab HIV-i vältimise vajalikkus üha rohkem kõlapinda kogu ühiskonnas ja poolele teele seisma jääda ei tohi. Kommenteerib Lääne-Tallinna Keskhaigla nakkuskeskuse juhataja Kai Zilmer

  12. NVGClient - Programový systém pro vizualizaci taktických dat ve 3D pro OTS VŘ PozS

    OpenAIRE

    Přenosil Václav; Františ Petr; Hodický Jan; Havelka Ladislav

    2012-01-01

    Program NVGClient je určený k přenosu taktických průsvitek z webové služby dle standardu NATO NVG do použitého vizualizačního programu. Při přenosu taktických průsvitek dochází k rozdělení jednotlivých grafických elementů (taktických značek) do určených kategorií a rovněž dochází k převodu symbolů (taktických značek) v přenášených průsvitkách dle kódu APP6B do jeho grafické podoby. Zároveň jsou taktické značky jednotek doplněny informacemi z příslušné databáze o jejich stavu (množství pohonný...

  13. Sociální dimenze optimálního vývoje: Otázky a výzvy

    Czech Academy of Sciences Publication Activity Database

    Millová, Katarína

    2016-01-01

    Roč. 60, Supplement 1 (2016), s. 76-85 ISSN 0009-062X R&D Projects: GA ČR GA15-22474S Institutional support: RVO:68081740 Keywords : optimal development * adaptive social functioning * longitudinal research Subject RIV: AN - Psychology Impact factor: 0.242, year: 2016

  14. Kulturismus a revoluce: K otázce sociálních dějin tělesnosti v Československu

    OpenAIRE

    Šabek, Jiří

    2016-01-01

    The thesis tries to process a topic of bodybuilding phenomenon in the wider context of the ideal body formation in modern age. Bodybuilding is understood as a specific socio-cultural phenomenon closely tied to a modern society and its historical development. Beyond the bodybuilding the work also deals with an analysis of the contemporary social body theory with focus on the domestic discourse and subsequently also with an analysis of discursive formation modern physicality from the Enlightenm...

  15. K otázce provenience svrchnokarbonských slepenců v severovýchodních Čechách

    Czech Academy of Sciences Publication Activity Database

    Mikuláš, Radek; Prouza, V.

    2008-01-01

    Roč. 2007, - (2008), s. 27-29 ISSN 0514-8057 R&D Projects: GA AV ČR IAA304130601 Institutional research plan: CEZ:AV0Z30130516 Keywords : Krkonoše Piedmont Basin * Intrasudetic Basin * Upper Carboniferous * Ordovician * Skolithos ichnofabric * conglomerates Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2007/2007-8.pdf

  16. Serbest Gezinmeli Sistemde Yem Formu ve Ot Varlığının Etlik Piliçlerde Performans Üzerine Etkileri

    Directory of Open Access Journals (Sweden)

    Bahattin Koçer

    2017-09-01

    Full Text Available This study was designed to investigate the effect of feed form (mesh or pellet and vegetation cover (available or unavailable on the growth performance, some organ weights and carcass characteristics of slow growing broiler chickens reared in the free range system in a 2x2 factorial design. A total of 800, day-old slow-growing broiler chickens (Hubbard Isa Red-JA 87 were randomly allotted into 4 dietary treatments, and 4 replicates of 50 birds. The effect of feed form was much more pronounced than forage intake in terms of body weight gain and feed conversion ratio with significant improvements in favour of pellet feed form. Throughout the experimental periods of 25 to 48 and 49 to 72, chicks fed on pellet feed gained more body weight which accompanied to lower feed conversion ratio compared to those receiving mesh feed. Pellet feed decreased feed consumption of birds from 25 to 48 days as compared to birds fed with mesh feed. However, this tendency disappeared thereafter and no significant difference was found between treatments throughout the experimental periods. Carcass yield of broiler chicks slaughtered at 72 days of age was not significantly affected by either feed form or green grass intake during the outdoor access.

  17. Ludický princip v kontextu otázky po zdařilém životě

    Czech Academy of Sciences Publication Activity Database

    Koubová, Alice

    2016-01-01

    Roč. 60, Suppl. 1 (2016), s. 31-40 ISSN 0009-062X R&D Projects: GA ČR(CZ) GJ16-00994Y Institutional support: RVO:67985955 Keywords : well-being * eudaimonia * ludic principle * play * game * ethics of virtues Subject RIV: AA - Philosophy ; Religion Impact factor: 0.242, year: 2016

  18. Measurement ot the switching over-voltages at the disconnection of the high voltage shunt reactors in the Romanian power system

    Energy Technology Data Exchange (ETDEWEB)

    Stroica, Paul Constantin; Merfu, Ion; Stroica, Mihail; Merfu, Marius; Cojocaru, Florian; Stefan, Dinu; Cojocaru, Mihai

    2010-09-15

    The paper presents the measurements of the switching over-voltages made in the Romanian Power System, at the 400/220/110 kV Urechesti substation at the disconnection of a 400 kV, 100 MVAr shunt reactor type DFAL, Siemens, Germany, in 3 consecutive versions. The first one is for shunt reactor controlled by live-tank oil circuit breaker, the second one is for shunt reactor controlled by SF6 circuit breaker, and the third one is for shunt reactor controlled by SF6 circuit breaker and synchronize device.

  19. Herxheim - odpověď na otázku krizového vývoje na konci kultury s lineární keramikou?

    Czech Academy of Sciences Publication Activity Database

    Končelová, Markéta

    Roč. 8, - ( 2007 ), s. 11-13 ISSN 1213-1628 Institutional research plan: CEZ:AV0Z80020508 Keywords : Herxheim * Linear Pottery culture * elliptical system of elongated pits * ritual practices Subject RIV: AC - Archeology, Anthropology, Ethnology

  20. 75 FR 42833 - Prohibited Service at Savings and Loan Holding Companies

    Science.gov (United States)

    2010-07-22

    ....treas.gov . OTS will post comments and the related index on the OTS Internet Site at http://www.ots... regulations applicable to savings associations under Regulation DD. Regulation DD implements the Truth in...

  1. A New Population of Parvocellular Oxytocin Neurons Controlling Magnocellular Neuron Activity and Inflammatory Pain Processing.

    Science.gov (United States)

    Eliava, Marina; Melchior, Meggane; Knobloch-Bollmann, H Sophie; Wahis, Jérôme; da Silva Gouveia, Miriam; Tang, Yan; Ciobanu, Alexandru Cristian; Triana Del Rio, Rodrigo; Roth, Lena C; Althammer, Ferdinand; Chavant, Virginie; Goumon, Yannick; Gruber, Tim; Petit-Demoulière, Nathalie; Busnelli, Marta; Chini, Bice; Tan, Linette L; Mitre, Mariela; Froemke, Robert C; Chao, Moses V; Giese, Günter; Sprengel, Rolf; Kuner, Rohini; Poisbeau, Pierrick; Seeburg, Peter H; Stoop, Ron; Charlet, Alexandre; Grinevich, Valery

    2016-03-16

    Oxytocin (OT) is a neuropeptide elaborated by the hypothalamic paraventricular (PVN) and supraoptic (SON) nuclei. Magnocellular OT neurons of these nuclei innervate numerous forebrain regions and release OT into the blood from the posterior pituitary. The PVN also harbors parvocellular OT cells that project to the brainstem and spinal cord, but their function has not been directly assessed. Here, we identified a subset of approximately 30 parvocellular OT neurons, with collateral projections onto magnocellular OT neurons and neurons of deep layers of the spinal cord. Evoked OT release from these OT neurons suppresses nociception and promotes analgesia in an animal model of inflammatory pain. Our findings identify a new population of OT neurons that modulates nociception in a two tier process: (1) directly by release of OT from axons onto sensory spinal cord neurons and inhibiting their activity and (2) indirectly by stimulating OT release from SON neurons into the periphery. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Etické otázky vědy v reflexi Církve československé (husitské) od jejího vzniku v r.1920 do současnosti

    Czech Academy of Sciences Publication Activity Database

    Lášek, Jan Blahoslav; Hrdlička, J.

    2008-01-01

    Roč. 79, 3-4 (2008), s. 440-478 ISSN 1211-7617 R&D Projects: GA AV ČR(CZ) IAA900090803 Institutional research plan: CEZ:AV0Z90090514 Keywords : Czechoslovak church * ethics Subject RIV: AA - Philosophy ; Religion

  3. Aktuální otázky adopce a výchovy dětí v homoparentálních rodinách

    OpenAIRE

    Lásková, Hana

    2012-01-01

    Bachelor thesis, "Current issues of adoption and education of children in homoparenting families" deals with the issue of homosexuality, a registered partnership, the possibilities of parenthood homosexual couples and the education of children in homoparenting families. In the beginning of my work I deal with the definition of homosexuality, causes of its origin, history and contemporary perspective on homosexuality and gay live opinions. Next there is a chapter about registered partnership, ...

  4. Turkey's Struggle with Internet in its 3rd year: Don Quixote, Ostrich, Harakiri 3. Yılında Türkiye'nin İnternetle Savaşı: Donkişot, Devekuşu, Harakiri

    Directory of Open Access Journals (Sweden)

    Mustafa Akgül

    2010-06-01

    Full Text Available The Code 5651 which sets Internet censhorship in Turkey has been active for 3 years. With this lawr, our country twanted to be a leader among democratic countries and challenged giant companies like Youtube and Google and fined them with tax penalty. Our country t is trying to set İnternational Law on Internet via code 5651 and decisions of its courts. But it doesn't do this by defending or negotiating the issue on international forums or United Nations. It considers Internet as media and it punishes and bans similar to printing press.. A serious number of people, including the Prime Minister, break the ban. The President of the Republic, State Minister for EU, Minister of Transportation and chairman of Information and Communication Technologies Authority give statements against these bans. In the meantime, rule of law, separation of powers, fair trial, and basic human rights such as freedom of expression are ignored. In other words, a Legal Tradegy occurs in front of lawyers and intellectuals. And our country commits hara-kiri by not understanding Internet, just like the situation in printing machine. In this article, various dimensions of the 3-year struggle of Turkey with Internet are discussed. Türkiye'de İnternet yasaklarını düzenleyen 5651 numaralı kanun çıkalı 3 yılı aştı. Bu kanunun çıkış sürecinde ve bugüne kadar uygulamasında, ülkemiz bir yandan dünyaya önderlik etmeye çalıştı, bir yandan Youtube/ Google gibi devlere meydan okudu; onlara büyük vergi cezaları kesti. Ülkemiz, kendi internet algılaması ve değerlendirmesini dünyaya empoze etmeye çalışıyor. Böylece, bu konuda, uluslararası hukuku tesis etmeye çalışıyor. Bunu, uluslararası forumlarda, Birleşmiş Milletlerde önererek, savunarak, müzakere ederek yapmıyor. İnterneti, basın gibi algılayarak, basına uygulanan yasaklama alışkanlıkları ile yasaklıyor. Başbakan dahil internet yasaklarını önemli bir çoğunluk deliyor. Bu yasaklara Cumhurbaşkanı, Avrupa Birliği’nden sorumlu Devlet Bakanı, hatta Ulaştırma Bakanı ve BTK (Bilgi Teknolojileri ve İletişim Kurumu Başkanı da karşı beyanlar veriyor. Bu arada Hukuk'un temel ilkeleri, kuvvetler ayrılığı, adil yargılama, özgürlüklerin özüne dokunulmaz ilkesi gözardı ediliyor. Bir başka deyişle, ülkenin hukukçuları ve düşünen insanların gözü önünde bir Hukuk Faciası yaşanıyor. Ve ülkemiz, matbaada olduğu gibi, interneti anlamayarak, harakiri yapıyor Bu yazıda, Türkiye'nin internetle savaşının 3 yıllık macerasının boyutları değerlendirecektir

  5. JETCAL 2000R Analyzer H337PA-603 Operational Test and Evaluation (OT&E) on H-53 E/J Aircraft and H46 D/E Aircraft

    Science.gov (United States)

    2003-01-28

    Proposal Title PORTABLE TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer NAVY/MARINE H53...B-4 Proposal Title PORTABLE TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer...TEST CELL - JETCAL 2000(R) Lead Proposer HOWELL INSTRUMENTS Military Customer NAVY/MARINE H53 AIRCRAFT Baseline Costs -- DoD’s Costs When COSSI is NOT

  6. "Slušný" Bursík a "neslušný" Železný v Otázkách Václava Moravce

    Czech Academy of Sciences Publication Activity Database

    Havlík, Martin

    -, 43/44 (2007), s. 33-68 ISSN 1211-5770 R&D Projects: GA ČR GA405/06/1468; GA AV ČR KJB900610701 Institutional research plan: CEZ:AV0Z90610518 Keywords : conversation analysis * turn-taking * sociolinguistics * language of politics Subject RIV: AI - Linguistics

  7. Příběh tří Mikulášů od Věže. Příspěvek k otázce jejich totožnosti

    Czech Academy of Sciences Publication Activity Database

    Musílek, Martin

    2013-01-01

    Roč. 29, č. 1 (2013), s. 2-15 ISSN 0231-6056 R&D Projects: GA ČR(CZ) GAP405/11/1982 Institutional support: RVO:67985955 Keywords : Prague * Prague’s Old Town * Brno * Tišnov * town elite * town seals * town genealogy Subject RIV: AB - History

  8. Aktuální právní otázky odpovědnosti dopravce při námořní přepravě zboží

    OpenAIRE

    Blahutová, Lenka

    2010-01-01

    in English The transport sector represents about 7% of European GDP. It should be also noted that European companies own 41% of the total world fleet capacity. As it can be seen, transport itself is an important industry and a major contributor to the functioning of not only the European economy but also the international economy. The maritime transport covers 80% of all trade exchange and has become the major transport sector in international business. The Hague, Hague-Visby (together so cal...

  9. K otázkám rétorické a empirické evidence v myšlení raného novověku

    Czech Academy of Sciences Publication Activity Database

    Řezníková, Lenka

    2016-01-01

    Roč. 13, č. 2 (2016), s. 195-210 ISSN 1214-7249 R&D Projects: GA ČR GB14-37038G Institutional support: RVO:67985955 Keywords : Rhetorical Evidence * Early Modern Thought * J. A. Comenius Subject RIV: AB - History

  10. La toxoplasmose oculaire : immunopathologie et Virulence : l'influence de la virulence du parasite sur les caractéristiques cliniques, biologiques et immunologiques de la toxoplasmose oculaire (OT) de l'Ancien et du Nouveau monde

    OpenAIRE

    De la Torre Cifuentes , Ligia Alejandra

    2013-01-01

    Ocular involvement, mainly retinochoroiditis, is one of the most severe sequelae of Toxoplasma gondii infection. However, the pathophysiological mechanisms of retinal destruction are poorly understood. Several studies suggested a more frequent and more severe ocular involvement in South American infections compared with European infections, probably due to different T. gondii strains (Type I/III, and atypical vs. Type II). To compare the clinical characteristics and biological and immunologic...

  11. Otázka slobodnej vôle v helenistickej filozofii (na pozadí Ciceronovho spisu De fato (Die Frage des freien Willens in der hellenistischen Philosophie (In Anbetracht der Ciceros Schrift De fato

    Directory of Open Access Journals (Sweden)

    Peter Fraňo

    2010-06-01

    Full Text Available In diesem Beitrag ich beschäftige mich mit der Frage: Ist das menschliche handeln vorbestimmt, oder kann der Einzelne frei entscheiden? Diese problematik wurde in der hellenistischen Philosophie sehr verbreitet. Das erste mal hat diese Frage Aristoteles in seinen Werken: Die Nikomachische Etik und vor allem De Interpretatione erforscht, wo hat sich die logische Problematik des sogenannten περὶ δυνατῶν berührt. Die megarischen Philosophen Diodoros Kronos und Philon von Megara hat auf die Lösung des Aristoteles reagiert. Außer der Logik ist die Problematik des freien Willes der Bestandteil der stoischen Physik (Astrologie, Sympathie uns stoische Ursachen gewesen. In meinem Beitrag ich habe auf diese Gesichtspunkte in Anbetracht der Ciceros Schrift De fato hingewiesen.

  12. Distribuce otěrových částic UHMWPE v periprotetických tkáních u TEP kyčelního kloubu

    Czech Academy of Sciences Publication Activity Database

    Pokorný, D.; Šlouf, Miroslav; Veselý, F.; Fulín, P.; Jahoda, D.; Sosna, A.; Běláček, J.; Landor, I.; Zolotarevova, E.; Popelka, S.

    2010-01-01

    Roč. 77, č. 2 (2010), s. 87-92 ISSN 0001-5415 R&D Projects: GA MŠk 2B06096 Institutional research plan: CEZ:AV0Z40500505 Keywords : total hip replacement * polyethylene wear * aseptic loosening Subject RIV: CD - Macromolecular Chemistry Impact factor: 1.628, year: 2009 http://www.achot.cz/detail.php?stat=346

  13. Dva dokumenty k otázce prodloužení dvouleté lhůty dodatkového protokolu československo-polské smlouvy z roku 1947

    Czech Academy of Sciences Publication Activity Database

    Friedl, Jiří

    2009-01-01

    Roč. 95, č. 4 (2009), s. 483-489 ISSN 0037-6922 R&D Projects: GA ČR GA409/09/0951 Institutional research plan: CEZ:AV0Z80150510 Keywords : Czechoslovakia * Poland * relations * treaty of alliance Subject RIV: AB - History

  14. Results of investigations of an 0.010-scale 140A/B configuration (model 72-OTS) of the Rockwell International space shuttle orbiter in the NASA/Langley Research Center unitary plan wind tunnel

    Science.gov (United States)

    Petrozzi, M. T.; Milam, M. D.

    1975-01-01

    Experimental aerodynamic investigations were conducted in the NASA/Langley unitary plan wind tunnel on a sting mounted 0.010-scale outer mold line model of the 140A/B configuration of the Rockwell International Space Shuttle Vehicle. The primary test objectives were to obtain: (1) six component force and moment data for the mated vehicle at subsonic and transonic conditions, (2) effects of configuration build-up, (3) effects of protuberances, ET/orbiter fairings and attach structures, and (4) elevon deflection effects on wing bending moment. Six component aerodynamic force and moment data and base and balance cavity pressures were recorded over Mach numbers of 1.6, 2.0, 2.5, 2.86, 3.9, and 4.63 at a nominal Reynolds number of 20 to the 6th power per foot. Selected configurations were tested at angles of attack and sideslip from -10 deg to +10 deg. For all configurations involving the orbiter, wing bending, and torsion coefficients were measured on the right wing.

  15. Otázka předlokačního a lokačního Brna v konfrontaci písemných a archeologických pramenů

    Czech Academy of Sciences Publication Activity Database

    Procházka, Rudolf

    2009-01-01

    Roč. 12, - (2009), s. 103-112. ISBN 978-80-89175-34-5. ISSN N R&D Projects: GA ČR GA404/09/1966 Institutional research plan: CEZ:AV0Z80010507 Keywords : Moravia * Town Brno * Late Middle age * foundations of the Town Subject RIV: AC - Archeology, Anthropology, Ethnology

  16. Šlechtické kapely v českých zemích doby baroka: staré a nové otázky jejich zkoumání

    Czech Academy of Sciences Publication Activity Database

    Kapsa, Václav

    2014-01-01

    Roč. 3, č. 1 (2014), s. 177-182 ISSN 1803-7747 Institutional support: RVO:68378076 Keywords : history of music * Bohemian lands * music ensembles * Kapellen * aristocracy Subject RIV: AL - Art, Architecture, Cultural Heritage http://www.acecs.cz/ media /cu_2014_03.pdf

  17. Ajakirjandusliku väljendusvabaduse erisused : ajakirjandusvabaduse aspekt sõnavabaduse piiramisel, arvestades Euroopa Inimõiguste Kohtu praktikat : [bakalaureusetöö] / Kristjan Ots ; Tartu Ülikool, õigusteaduskond ; juhendaja: Kalle Merusk

    Index Scriptorium Estoniae

    Ots, Kristjan, 1976-

    2001-01-01

    Sõnavabaduse mõiste, koht konstitutsioonis, sõnavabaduse piiramise piirid, tsensuur, ajakirjandusvabaduse eristamine sõnavabadusest, ajakirjandusliku väljendusvabaduse põhimõtted, ajakirjanduse funktsioonid, sõnavabaduse aspekt, teabevabaduse aspekt, teotamine e. difamatsioon, ajakirjandusvabaduse piiramine õigusemõistmise huvides

  18. Sociálně pedagogické otázky integrace romských dětí a mládeže

    OpenAIRE

    Čadová, Markéta

    2010-01-01

    This work is of a theoretical-empirical nature. The goal of this work is to identify causes with lead to the social exclusion of the Romany ethnic group, to chart trends in this region, and to focus attention on institutions engaged in integrating Roma into society. Additional goals are to determine how the integration of this minority is secured by the government, through self-government and non-profit organizations, and subsequently to attempt to determine how the Roma people and the majori...

  19. Identificación de escenarios de calidad de hábitat para fauna silvestre : caso de estudio| cuenca media y alta del río Otún (Risaralda)

    OpenAIRE

    García Gómez, Martha Patricia

    2009-01-01

    Este trabajo contiene eje clave de investigación las dinámicas espaciales de cambio en la calidad del hábitat para fauna silvestre, a partir de la transformación de coberturas dentro de las áreas protegidas (sistemas naturales) y los sistemas reproductivos. Se presenta la estructura de un modelo basado en la utilización de software SIG. Lógica difusa y Agentes Inteligentes a partir del cual se logra la simulación de escenarios de calidad de hábitat para la especie ?zorros? en la cuenca media ...

  20. Svědectví písemných pramenů k otázce vyměřování velkých návsí na Rakovnicku

    Czech Academy of Sciences Publication Activity Database

    Dohnal, Martin

    2013-01-01

    Roč. 39, č. 2 (2013), s. 213-235 ISSN 0323-0988 R&D Projects: GA ČR(CZ) GAP410/11/1287 Keywords : urbanism * medieval settlement * Early Modern settlement * 1200-1900 * Bratronice (district of Rakovník) Subject RIV: AC - Archeology, Anthropology, Ethnology

  1. Estructura funcional y composición de la comunidad de pequeños mamíferos terrestres en el bosque andino del santuario de flora y fauna Otún Quimbaya, Risaralda

    Directory of Open Access Journals (Sweden)

    Swanni Alvarado R.

    2005-07-01

    que el BNM tiene los valores más altos de diversidad y la mayor riqueza, mientras que la menor diversidad y riqueza fue encontrada en el BR. El BNM y el BR son más similares según el índice de Morisita y un análisis de Cluster. Para ordenar las especies por las variables morfológicas externas se realizó un Análisis de Componentes Principales, el cual mostró una agrupación de especies pequeñas y otra de especies intermedias, que podría estar indicando que no hay una competencia marcada por un mismo recurso.

  2. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot Transonic wind tunnel (IA613A), volume 1

    Science.gov (United States)

    Marroquin, J.; Lemoine, P.

    1992-01-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e. top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  3. Base pressure and heat transfer tests of the 0.0225-scale space shuttle plume simulation model (19-OTS) in yawed flight conditions in the NASA-Lewis 10x10-foot supersonic wind tunnel (test IH83)

    Science.gov (United States)

    Foust, J. W.

    1979-01-01

    Wind tunnel tests were performed to determine pressures, heat transfer rates, and gas recovery temperatures in the base region of a rocket firing model of the space shuttle integrated vehicle during simulated yawed flight conditions. First and second stage flight of the space shuttle were simulated by firing the main engines in conjunction with the SRB rocket motors or only the SSME's into the continuous tunnel airstream. For the correct rocket plume environment, the simulated altitude pressures were halved to maintain the rocket chamber/altitude pressure ratio. Tunnel freestream Mach numbers from 2.2 to 3.5 were simulated over an altitude range of 60 to 130 thousand feet with varying angle of attack, yaw angle, nozzle gimbal angle and SRB chamber pressure. Gas recovery temperature data derived from nine gas temperature probe runs are presented. The model configuration, instrumentation, test procedures, and data reduction are described.

  4. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93), volume 2

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and plotted coefficient data are presented for an aero-loads investigation on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed.

  5. Results of wind tunnel tests of an ASRM configured 0.03 scale Space Shuttle integrated vehicle model (47-OTS) in the AEDC 16-foot transonic wind tunnel, volume 2

    Science.gov (United States)

    Marroquin, J.; Lemoine, P.

    1992-01-01

    An experimental Aerodynamic and Aero-Acoustic loads data base was obtained at transonic Mach numbers for the Space Shuttle Launch Vehicle configured with the ASRM Solid Rocket Boosters as an increment to the current flight configuration (RSRB). These data were obtained during transonic wind tunnel tests (IA 613A) conducted in the Arnold Engineering Development Center 16-Foot transonic propulsion wind tunnel from March 27, 1991 through April 12, 1991. This test is the first of a series of two tests covering the Mach range from 0.6 to 3.5. Steady state surface static and fluctuating pressure distributions over the Orbiter, External Tank and Solid Rocket Boosters of the Shuttle Integrated Vehicle were measured. Total Orbiter forces, Wing forces and Elevon hinge moments were directly measured as well from force balances. Two configurations of Solid Rocket Boosters were tested, the Redesigned Solid Rocket Booster (RSRB) and the Advanced Solid Rocket Motor (ASRM). The effects of the position (i.e., top, bottom, top and bottom) of the Integrated Electronics Assembly (IEA) box, mounted on the SRB attach ring, were obtained on the ASRM configured model. These data were obtained with and without Solid Plume Simulators which, when used, matched as close as possible the flight derived pressures on the Orbiter and External Tank base. Data were obtained at Mach numbers ranging from 0.6 to 1.55 at a Unit Reynolds Number of 2.5 million per foot through model angles of attack from -8 to +4 degrees at sideslip angles of 0, +4 and -4 degrees.

  6. Results of investigations conducted in the LaRC 8-foot transonic pressure tunnel using the 0.010-scale 72-OTS model of the space shuttle integrated vehicle (IA93)

    Science.gov (United States)

    Nichols, M. E.

    1976-01-01

    Test procedures, history, and data from the wind tunnel test are presented. Aero-loads were investigated on the updated configuration-5 space shuttle launch vehicle at Mach numbers from 0.600 to 1.205. Six-component vehicle forces and moments, base and sting-cavity pressures, elevon hinge moments, wing-root bending and torsion moments, and normal shear force data were obtained. Full simulation of updated vehicle protuberances and attach hardware was employed. Various elevon deflection angles were tested with two different forward orbiter-to-external-tank attach-strut configurations. The entire model was supported by means of a balance mounted in the orbiter through its base and suspended from a sting.

  7. K otázce lidských práv tzv. druhé generace a jejich reflex do ústavního práva na lidskou důstojnost

    Czech Academy of Sciences Publication Activity Database

    Güttler, Vojen

    2014-01-01

    Roč. 153, č. 6 (2014), s. 501-511 ISSN 0231-6625 Institutional support: RVO:68378122 Keywords : human rights * social rights * Charter of Fundamental Rights and Freedoms Subject RIV: AG - Legal Sciences

  8. Slovarnõi zapass; Utrennjaja muzõka; Mõsl; Absoljutnõi jumor : tshitaja Jannisa Ritsosa; Ne prihhodi; Ne pomnju; Svet vdohnovenja; 'Kogda ot imeni tehh...'; 'Kto szhalitsja kto pozhalejet tehh...'; 'Na povorote skrezheshtshet tramvai...'; Prosto

    Index Scriptorium Estoniae

    Traat, Mats, 1936-

    1996-01-01

    Orig.: Sõnavara; Hommikumuusika; Mõte; Absoluutne huumor : Jannis Ritsost lugedes; Ära tule; Ei mäleta; "Kui nende nimel..."; "Kes heidab armu neile..."; "Pöörakul krigiseb tramm..."; Lihtsa naise elu

  9. Bydlení, bytová otázka a bytové poměry v Baťově Zlíně v letech 1918- 1938

    Czech Academy of Sciences Publication Activity Database

    Ševeček, Ondřej

    2006-01-01

    Roč. 104, č. 1 (2006), s. 18-48 ISSN 0037-6833 Institutional research plan: CEZ:AV0Z90090514 Keywords : Urbanization * industrial housing * company town Zlin * Bata company Subject RIV: AA - Philosophy ; Religion

  10. Nové poznatky a otázky nad hrádkem Rohy u Skřinářova, okr. Zďár n. S.

    Czech Academy of Sciences Publication Activity Database

    Unger, J.; Velek, J.; Kirchner, Karel; Zduba, J.

    2017-01-01

    Roč. 69, č. 3 (2017), s. 252-258 ISSN 0323-2581 Institutional support: RVO:68145535 Keywords : Moravia * middle ages * castle * colonization * mining Subject RIV: AC - Archeology, Anthropology, Ethnology OBOR OECD: Antropology, ethnology

  11. Kiril Christov - pevec neudovletvoren, no neizpadašt v otčajanie... Kăm văprosa za rannata recepcija na tvorčestvoto mu v Čechija (do 1918 g.)

    Czech Academy of Sciences Publication Activity Database

    Černý, Marcel

    2017-01-01

    Roč. 5, č. 10 (2017) ISSN 1314-9067 Institutional support: RVO:68378017 Keywords : Khristov, Kiril * Prague * artistic translation * literary reception * Czech-Bulgarian cultural relations * Bulgarian opera * literary adaptation of folklore * eroticism * Šak, Vladislav * Tichý, František Rut Tichý = Broman, Zdeněk * Macháň, Karel * Páta, Josef Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures http://www.abcdar.com/magazine/X/%C4%8Cern%C3%BD_1314-9067_X.pdf

  12. Česká počítačově generovaná literatura a otázka autorství literárního textu

    Czech Academy of Sciences Publication Activity Database

    Piorecký, Karel

    2017-01-01

    Roč. 9, č. 3 (2017), s. 66-78 ISSN 1337-9275 R&D Projects: GA MŠk(CZ) EF16_013/0001743 Institutional support: RVO:68378068 Keywords : generative literature * glitch art * google poetry * artificial intelligence * authorship * network theory of actors Subject RIV: AJ - Letters, Mass-media, Audiovision OBOR OECD: Specific literatures

  13. Experimental study of isospin mixing in 12C + n → 13C(T = 3/2) and 16O + n → 17O(T = 3/2) resonances

    International Nuclear Information System (INIS)

    Cierjacks, S.; Schmalz, G.; Hinterberger, F.; Rossen, P. v.

    1981-12-01

    Narrow resonances of 13 C and 17 O have been studied by a measurement of the total neutron cross sections of carbon and oxygen between 3 and 30 MeV. Employing the improved time-of-flight spectrometer at the Karlsruhe Isochronous Cyclotron and precise calibration methods, resonance cross sections were measured with an energy resolution of 1:2100 at 10 MeV and energy accuracies between 10 -4 and 10 -5 . Resonance analysis of the measured data provided parameters for numerous narrow states of both isospins, T = 1/2 and T = 3/2. These data in conjunction with information from broad T = 1/2 resonances provided a good means to experimentally determine isospin mixing matrix elements. Results were obtained for the first five T = 3/2 resonances in 17 O and the first T = 3/2 resonance in 13 C. The obtained mixing matrix elements are compared with previous experimental results and shell-modell predictions of this quantity. (orig.) [de

  14. Non-orthogonally transitive G2 spike solution

    International Nuclear Information System (INIS)

    Lim, Woei Chet

    2015-01-01

    We generalize the orthogonally transitive (OT) G 2 spike solution to the non-OT G 2 case. This is achieved by applying Geroch’s transformation on a Kasner seed. The new solution contains two more parameters than the OT G 2 spike solution. Unlike the OT G 2 spike solution, the new solution always resolves its spike. (fast track communication)

  15. Urinary and plasma oxytocin changes in response to MDMA or intranasal oxytocin administration.

    Science.gov (United States)

    Francis, Sunday M; Kirkpatrick, Matthew G; de Wit, Harriet; Jacob, Suma

    2016-12-01

    The neuropeptide oxytocin (OT) has received increased experimental attention for its putative role in both normal social functioning and several psychiatric disorders that are partially characterized by social dysfunction (e.g., autism spectrum disorders: ASD). Many human experimental studies measure circulating plasma levels of OT in order to examine the relationship between the hormone and behavior. Urinary OT (uOT) assays offer a simple, easy, and non-invasive method to measure peripheral hormone levels, but the correspondence between uOT and plasma OT (pOT) levels is unclear. Here, we conducted two within-subjects, double-blind studies exploring changes in uOT and pOT levels following administration of two drugs: MDMA, an oxytocin-releasing drug (Study 1), and intranasal oxytocin (INOT: Study 1 and 2). In Study 1, 14 adult participants (2 females) were each administered either oral 1.5mg/kg MDMA or 40IU INOT across two different study sessions. In Study 2, 10 male participants (adolescents and young adults) diagnosed with ASD received either 40IU INOT or placebo across two different sessions. In both studies, blood and urine samples were collected before and after drug administration at each study session. For Study 1, 10 participants provided valid plasma and urine samples for the MDMA session, and 8 provided valid samples for the INOT session. For Study 2, all 10 participants provided valid samples for both INOT and placebo sessions. Pre- and post-administration levels of pOT and uOT were compared. Additionally, correlations between percent change from baseline uOT and pOT levels were examined. Study 1: Plasma OT and uOT levels significantly increased after administration of MDMA and INOT. Furthermore, uOT levels were positively correlated with pOT levels following administration of MDMA (r=0.57, p=0.042) but not INOT (r=0.51, p=0.097). Study 2: There was a significant increase in uOT levels after administration of INOT, but not after administration of

  16. Effect of oxytocin injection to milching buffaloes on its content & stability in milk

    Directory of Open Access Journals (Sweden)

    Raghu Pullakhandam

    2014-01-01

    Full Text Available Background & objectives: Oxytocin (OT injections to milch cattle for milk letdown have become a common practice amongst dairy farmers in India. Although there is no reported evidence, it is widely presumed that long term consumption of such milk leads to adverse health consequences. However, there is no information on the effect of exogenous OT injections on milk OT content and its stability during heating and gastrointestinal digestion. This study was carried out to determine the OT content in milk samples given by buffaloes with and without OT injections and to assess the stability of OT in the milk. Methods: Milk samples from milch buffaloes (Murrah buffalo were collected from local farmers with (n=121 or without (n=120 exogenous OT injections during 3 to 5 months of lactation period. The OT content of milk samples was estimated by competitive enzyme immunoassay (EIA. The thermal and digestive stability of OT was assessed by in silico and in vitro digestion methods. Results: The OT content of the milk samples was similar regardless of OT injections used. Further, OT was found to be stable to heat treatment and gastric pepsin digestion while it was rapidly digested during the simulated intestinal digestion. r0 educed OT was digested by pepsin, implying that internal disulphide bridge of OT rendered the peptide resistant to peptic digestion. On the other hand, phenylmethylsulphonyl fluoride (PMSF, a serine protease inhibitor, abrogated the pancreatin induced digestion of OT. Interpretation & conclusions: These findings suggest that exogenous OT injections do not influence its content in milk. Further, OT present in milk is rapidly degraded during intestinal digestion, ruling out its intestinal absorption and associated adverse health consequences, if any.

  17. 75 FR 35686 - Community Reinvestment Act Regulation Hearings

    Science.gov (United States)

    2010-06-23

    ... will post comments on the OTS Internet Site at http://www.ots.treas.gov/?p=LawsRegulations . Viewing... consider violations of additional consumer laws, such as the Truth in Savings Act, the Electronic Fund...

  18. Body composition, metabolism, sleep, psychological and eating patterns of overtraining syndrome: Results of the EROS study (EROS-PROFILE).

    Science.gov (United States)

    Cadegiani, Flavio A; Kater, Claudio E

    2018-08-01

    Overtraining syndrome (OTS) is caused by an imbalance between training, nutrition and resting, and leads to decreased performance and fatigue; however, the precise underlying triggers of OTS remain unclear. This study investigated the body composition, metabolism, eating, sleeping patterns and mood states among participants with OTS. Selected participants were divided into OTS-affected athletes (OTS, n = 14), healthy athletes (ATL, n = 25), and healthy non-physically active controls (NCS, n = 12). Compared to ATL, OTS showed decreased sleep quality (p = 0.004); increased duration of work or study (p sleep, and increased cognitive activity are likely OTS triggers. OTS appears to induce dehydration, increase body fat, decrease libido, and worsen mood.

  19. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... a spinal cord injury important? play_arrow What role does “compression” play in a spinal cord injury? ...

  20. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... L Sarah Harrison, OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury ... do to prevent pressure sores? play_arrow What role does diet and hydration play in preventing pressure ...

  1. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW Marguerite ... play_arrow What are the latest developments in the use of electrical stimulation for spinal ...

  2. Awareness and Use of Electronic Health Records in Entry-Level Occupational Therapy and Occupational Therapy Assistant Curricula

    Directory of Open Access Journals (Sweden)

    Louis F. Dmytryk

    2017-03-01

    Full Text Available The Accreditation Council for Occupational Therapy Education (ACOTE requires programs to instruct entrylevel occupational therapy (OT and occupational therapy assistant (OTA students in technology that may include electronic documentation systems, distance communication, virtual environments, and telehealth (standard B1.8. At this time, there are no publications describing if and how electronic health record (EHR instruction is implemented in entry-level OT and OTA programs. The purpose of this study is to investigate awareness and use of EHRs in entry-level OT and OTA curricula. Respondents from 76 nationally accredited entry-level programs (two OT doctoral, 24 OT masters, two OT combined bachelors/masters, and 48 OTA completed a survey. The findings showed inconsistent and incomplete EHR instruction in entry-level OT and OTA education. This study provides a baseline for investigating best practices in EHR education for entrylevel OT and OTA students

  3. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  4. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  5. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  6. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ... Experiences By Topic Resources Blog Peer Counseling About Media Donate Contact Us Terms of Use Site Map ...

  7. Spinal Cord Injury 101

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  8. Basics of SCI Rehabilitation

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  9. Sex and Fertility After SCI

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  10. Preventing Pressure Sores

    Medline Plus

    Full Text Available ... SCI Rehabilitation Donald Peck Leslie, MD Adjusting to Social Life in a Wheelchair Lisa Rosen, MS Spasticity, ... OT Anne Bryden, OT The Role of the Social Worker after Spinal Cord Injury Patti Rogers, SW ...

  11. Occupational Therapy intervention for patiens with COPD, Rehabilitation at home

    DEFF Research Database (Denmark)

    Larsen, Stina Meyer; Petersen, Anne Karin

    Describe and demonstrate Occupational Therapy (OT) intervention for patients with Chronic Obstructive Pulmonary Disease (COPD).......Describe and demonstrate Occupational Therapy (OT) intervention for patients with Chronic Obstructive Pulmonary Disease (COPD)....

  12. Low dose intranasal oxytocin delivered with Breath Powered device dampens amygdala response to emotional stimuli: A peripheral effect-controlled within- subjects randomized dose-response fMRI trial

    OpenAIRE

    Quintana, Daniel; Westlye, Lars Tjelta; Alnæs, Dag; Rustan, Øyvind; Kaufmann, Tobias; Smerud, Knut Terje; Mahmoud, Ramy; Djupesland, Per G.; Andreassen, Ole Andreas

    2016-01-01

    It is unclear if and how exogenous oxytocin (OT) reaches the brain to improve social behavior and cognition and what is the optimal dose for OT response. To better understand the delivery routes of intranasal OT administration to the brain and the dose-response, we compared amygdala response to facial stimuli by means of functional magnetic resonance imaging (fMRI) in four treatment conditions, including two different doses of intranasal OT using a novel Breath Powered device, intravenous (IV...

  13. The role of oxytocin in cardiovascular regulation

    Directory of Open Access Journals (Sweden)

    J. Gutkowska

    2014-03-01

    Full Text Available Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i lowering blood pressure, ii negative inotropic and chronotropic effects, iii parasympathetic neuromodulation, iv vasodilatation, v anti-inflammatory activity, vi antioxidant activity, and vii metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions.

  14. Entry-Level Doctorate for Occupational Therapists: An Assessment of Attitudes of Occupational Therapists and Occupational Therapy Assistants

    Science.gov (United States)

    McCombie, Randy P.

    2016-01-01

    Purpose: The purpose of this study was to survey occupational therapists (OTs) and occupational therapy assistants (OTAs) on their attitudes toward a possible move to the entry-level doctorate as the mandated singular point of entry into the profession for OTs. Method: The study surveyed a random sample of 600 OTs and 600 OTAs from two…

  15. REGULATION OF THE RAT OXYTOCIN GENE BY ESTRADIOL - EXAMINATION OF PROMOTER ACTIVITY IN TRANSFECTED CELLS AND OF MESSENGER-RIBONUCLEIC-ACID AND PEPTIDE LEVELS IN THE HYPOTHALAMONEUROHYPOPHYSEAL SYSTEM

    NARCIS (Netherlands)

    BURBACH, JPH; ADAN, RAH; VANTOL, HHM; VERBEECK, MAE; AXELSON, JF; VANLEEUWEN, FW; BEEKMAN, JM; AB, G

    1990-01-01

    Oxytocin (OT) plays a role in reproduction at the level of the pituitary and mammary glands and uterus. This OT is synthesized in the hypothalamo-neurohypophyseal system (HNS). A number of observations have suggested that estrogens regulate the production of OT in the HNS. In this study the effect

  16. Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders

    Directory of Open Access Journals (Sweden)

    Valery eGrinevich

    2015-01-01

    Full Text Available Oxytocin (OT, the main neuropeptide of sociality, is expressed in neurons exclusively localized in the hypothalamus. During the last decade, a plethora of neuroendocrine, metabolic, autonomic and behavioral effects of OT has been reported. In the urgency to find treatments to syndromes as invalidating as autism, many clinical trials have been launched in which OT is administered to patients, including adolescents and children. However, the impact of OT on the developing brain and in particular on the embryonic and early postnatal maturation of OT neurons, has been only poorly investigated. In the present review we summarize available (although limited literature on general features of ontogenetic transformation of the OT system, including determination, migration and differentiation of OT neurons. Next, we discuss trajectories of OT receptors (OTR in perinatal period. Furthermore, we provide evidence that early alterations, from birth, in the central OT system lead to severe neurodevelopmental diseases such as feeding deficit in infancy and severe defects in social behavior in adulthood, as described in Prader-Willi syndrome. Our review intends to propose a hypothesis about developmental dynamics of central OT pathways, which are essential for survival right after birth and for the acquisition of social skills later on. A better understanding of the embryonic and early postnatal maturation of the OT system may lead to better OT-based treatments in Prader-Willi syndrome and autism.

  17. Anatomy in Occupational Therapy Program Curriculum: Practitioners' Perspectives

    Science.gov (United States)

    Schofield, Katherine Anne

    2014-01-01

    Anatomy education is undergoing significant transformation. It is unknown whether changes are in accordance with occupational therapy (OT) practice needs. The purpose of this pilot study was to survey OT clinicians to determine their perspectives on the value of anatomy in OT curricula, and anatomical knowledge required for practice. In addition…

  18. 32 CFR 3.4 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... responsible for approving the OTs acquisition strategy and resulting OT agreement. This official must be at least one level above the Agreements Officer and at no lower level than existing agency thresholds associated with procurement contracts. Awardee. Any business unit that is the direct recipient of an OT...

  19. The Profile of Mood State (POMS) questionnaire as an indicator of ...

    African Journals Online (AJOL)

    The overtraining syndrome (OTS) is largely a diagnosis of exclusion. The aim of this study was to investigate the compact Profile of Mood State (POMS) questionnaire as an early and accurate indicator for the diagnosis of OTS and the reliability of such findings in a group of athletes diagnosed with OTS, in comparison with a ...

  20. The role of oxytocin in cardiovascular regulation

    International Nuclear Information System (INIS)

    Gutkowska, J.; Jankowski, M.; Antunes-Rodrigues, J.

    2014-01-01

    Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs) has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i) lowering blood pressure, ii) negative inotropic and chronotropic effects, iii) parasympathetic neuromodulation, iv) vasodilatation, v) anti-inflammatory activity, vi) antioxidant activity, and vii) metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions

  1. Planets Move in Circles !

    Indian Academy of Sciences (India)

    calculus can be done by geometry' and our problem is no exception. The geometrical derivation is quite simple: In a small time interval ot, the magnitude of the velocity changes by ~V= f (GM/r2) ot according to Newton's law. The angle changes by. ~e = (h/r2) ot from the conservation of angular momentum. Dividing the two ...

  2. The role of oxytocin in cardiovascular regulation

    Energy Technology Data Exchange (ETDEWEB)

    Gutkowska, J.; Jankowski, M. [University of Montreal, CHUM Research Centre, Faculty of Medicine, Department of Medicine, Laboratory of Cardiovascular Biochemistry, Montreal, Quebec, Canada, Laboratory of Cardiovascular Biochemistry, Department of Medicine, Faculty of Medicine, University of Montreal, CHUM Research Centre, Montreal, Quebec (Canada); Antunes-Rodrigues, J. [Universidade de São Paulo, Faculdade de Medicina de Ribeirão Preto, Departamento de Fisiologia, Ribeirão Preto, SP, Brasil, Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP (Brazil)

    2014-03-03

    Studies of body volume expansion have indicated that lesions of the anteroventral third ventricle and median eminence block the release of atrial natriuretic peptide (ANP) into the circulation. Detailed analysis of the lesions showed that activation of oxytocin (OT)-ergic neurons is responsible for ANP release, and it has become clear that activation of neuronal circuitry elicits OT secretion into the circulation, activating atrial OT receptors and ANP release from the heart. Subsequently, we have uncovered the entire functional OT system in the rat and the human heart. An abundance of OT has been observed in the early development of the fetal heart, and the capacity of OT to generate cardiomyocytes (CMs) has been demonstrated in various types of stem cells. OT treatment of mesenchymal stem cells stimulates paracrine factors beneficial for cardioprotection. Cardiovascular actions of OT include: i) lowering blood pressure, ii) negative inotropic and chronotropic effects, iii) parasympathetic neuromodulation, iv) vasodilatation, v) anti-inflammatory activity, vi) antioxidant activity, and vii) metabolic effects. OT actions are mediated by nitric oxide and ANP. The beneficial actions of OT may include the increase in glucose uptake by CMs and stem cells, reduction in CM hypertrophy, oxidative stress, and mitochondrial protection of several cell types. In experimentally induced myocardial infarction in rats, continuous in vivo OT delivery improves cardiac healing and cardiac work, reduces inflammation, and stimulates angiogenesis. Because OT plays anti-inflammatory and cardioprotective roles and improves vascular and metabolic functions, it demonstrates potential for therapeutic use in various pathologic conditions.

  3. 77 FR 20104 - Privacy Act of 1974, as Amended; System of Records

    Science.gov (United States)

    2012-04-03

    ... Locator File OTS .012--Payroll/Personnel Systems & Payroll Records OTS .013--Mass Communication System OTS... examination or investigation; (3) The news media in accordance with guidelines contained in 28 CFR 50.2; (4... Information Act Officer, Communications Division, Mailstop 2-3, Office of the Comptroller of the Currency, 250...

  4. Maternal and Paternal Plasma, Salivary, and Urinary Oxytocin and Parent-Infant Synchrony: Considering Stress and Affiliation Components of Human Bonding

    Science.gov (United States)

    Feldman, Ruth; Gordon, Ilanit; Zagoory-Sharon, Orna

    2011-01-01

    Studies in mammals have implicated the neuropeptide oxytocin (OT) in processes of bond formation and stress modulation, yet the involvement of OT in human bonding throughout life remains poorly understood. We assessed OT in the plasma, saliva, and urine of 112 mothers and fathers interacting with their 4-6-month-old infants. Parent-infant…

  5. Comparison of Oral, Tympanic and Fresh Urine Temperature in ...

    African Journals Online (AJOL)

    Background: Core body temperature (CBT) is commonly evaluated by measuring oral (OT) and tympanic membrane (TT) temperatures; however, there are considerable debates on which of these methods is the most appropriate. Objective: To evaluate concordance of OT and TT with CBT. Material and Methods: OT, TT and ...

  6. Oxytocin in the prelimbic medial prefrontal cortex reduces anxiety-like behavior in female and male rats.

    Science.gov (United States)

    Sabihi, Sara; Durosko, Nicole E; Dong, Shirley M; Leuner, Benedetta

    2014-07-01

    The neuropeptide oxytocin (OT) is anxiolytic in rodents and humans. However, the specific brain regions where OT acts to regulate anxiety requires further investigation. The medial prefrontal cortex (mPFC) has been shown to play a role in the modulation of anxiety-related behavior. In addition, the mPFC contains OT-sensitive neurons, expresses OT receptors, and receives long range axonal projections from OT-producing neurons in the hypothalamus, suggesting that the mPFC may be a target where OT acts to diminish anxiety. To investigate this possibility, female rats were administered OT bilaterally into the prelimbic (PL) region of the mPFC and anxiety-like behavior assessed. In addition, to determine if the effects of OT on anxiety-like behavior are sex dependent and to evaluate the specificity of OT, male and female anxiety-like behavior was tested following delivery of either OT or the closely related neuropeptide arginine vasopressin (AVP) into the PL mPFC. Finally, the importance of endogenous OT in the regulation of anxiety-like behavior was examined in male and female rats that received PL infusions of an OT receptor antagonist (OTR-A). Overall, even though males and females showed some differences in their baseline levels of anxiety-like behavior, OT in the PL region of the mPFC decreased anxiety regardless of sex. In contrast, neither AVP nor an OTR-A affected anxiety-like behavior in males or females. Together, these findings suggest that although endogenous OT in the PL region of the mPFC does not influence anxiety, the PL mPFC is a site where exogenous OT may act to attenuate anxiety-related behavior independent of sex. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Sex-Specific Effects of Stress on Oxytocin Neurons Correspond With Responses to Intranasal Oxytocin.

    Science.gov (United States)

    Steinman, Michael Q; Duque-Wilckens, Natalia; Greenberg, Gian D; Hao, Rebecca; Campi, Katharine L; Laredo, Sarah A; Laman-Maharg, Abigail; Manning, Claire E; Doig, Ian E; Lopez, Eduardo M; Walch, Keenan; Bales, Karen L; Trainor, Brian C

    2016-09-01

    Oxytocin (OT) is considered to be a stress-buffering hormone, dampening the physiologic effects of stress. However, OT can also be anxiogenic. We examined acute and long-lasting effects of social defeat on OT neurons in male and female California mice. We used immunohistochemistry for OT and c-fos cells to examine OT neuron activity immediately after defeat (n = 6-9) and 2 weeks (n = 6-9) and 10 weeks (n = 4-5) later. We quantified Oxt messenger RNA with quantitative polymerase chain reaction (n = 5-9). Intranasal OT was administered to naïve and stressed mice tested in social interaction and resident-intruder tests (n = 8-14). Acute exposure to a third episode of defeat increased OT/c-fos colocalizations in the paraventricular nucleus of both sexes. In the medioventral bed nucleus of the stria terminalis, defeat increased Oxt messenger RNA, total OT neurons, and OT/c-fos colocalizations in female mice but not male mice. Intranasal OT failed to reverse stress-induced social withdrawal in female mice and reduced social interaction behavior in female mice naïve to defeat. In contrast, intranasal OT increased social interaction in stressed male mice and reduced freezing in the resident-intruder test. Social defeat induces long-lasting increases in OT production and OT/c-fos cells in the medioventral bed nucleus of the stria terminalis of female mice but not male mice. Intranasal OT largely reversed the effects of stress on behavior in male mice, but effects were mixed in female mice. These results suggest that changes in OT-sensitive networks contribute to sex differences in behavioral responses to stress. Copyright © 2015 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  8. Cigarette smoke inhalation increases the alveolar bone loss caused by primary occlusal trauma in a rat model.

    Science.gov (United States)

    Campos, M L G; Corrêa, M G; Júnior, F H N; Casati, M Z; Sallum, E A; Sallum, A W

    2014-04-01

    Occlusal trauma (OT) and smoking are both factors that alter alveolar bone metabolism and therefore could synergistically act on alveolar bone loss. The aim of this experimental study was to evaluate the influence of short-term cigarette smoke inhalation (CSI) on inter-radicular alveolar bone loss promoted by primary OT in a rat model. Forty-eight animals were randomly assigned to one of three groups based on treatment type: OT + CSI (n = 16), animals were exposed to CSI three times per day, for 8 min per exposure, and they concomitantly received unilateral vertical augmentation creating an occlusal interference inducing experimental OT; OT (n = 16), animals received only unilateral vertical augmentation; negative control (NC; n = 16), animals maintained for equal periods to achieve periodontal baseline values of periodontal ligament dimension. Each group was divided into two subgroups (n = 8) based on treatment length: 7 or 14 d. After 7 d, the OT + CSI group exhibited significantly higher bone loss compared to the NC group (p = 0.0022). After 14 d, the OT (p < 0.0001) and OT + CSI (p < 0.0001) groups presented significantly higher bone loss compared to the NC group, and OT + CSI resulted in significantly higher bone loss than OT alone (p = 0.0241). The number of tartrate-resistant acid phosphatase-positive cells on the linear surface of the bone crest after 7 d was significantly higher in the OT + CSI group as compared to the NC and OT groups (p < 0.0001 and p = 0.0045, respectively) and remained significantly higher in the OT + CSI group after 14 d, compared to the OT group (p < 0.0001). Short-term CSI increases early bone loss in association with OT after 7 d, and this worsens in severity after 14 d of exposure. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Association of Oxytocin and Parental Prefrontal Activation during Reunion with Infant: A Functional Near-Infrared Spectroscopy Study

    Directory of Open Access Journals (Sweden)

    Jun Ito

    2017-12-01

    Full Text Available Although previous studies have revealed the role of oxytocin (OT in parental behavior, the role of OT has not been investigated through the direct assessment of prefrontal brain activation during parenting. By using functional near-infrared spectroscopy, we aimed to show the relationship between parental [maternal (N = 15 and paternal (N = 21] OT levels and the activation of the prefrontal cortex (PFC, while holding their infants after separation. Baseline OT levels were measured in the subjects’ saliva samples before the experiment. Prefrontal brain activation was assessed in participants sitting alone on a chair (i.e., separation from their infant for 120 s and during the target period (i.e., holding their infant for 45 s, which was done in triplicate. The oxygen hemoglobin (oxy-Hb dissociation curve significantly increased in 9 out of 22 channels on the PFC when maternal and paternal samples were combined. However, only the fathers showed a correlation between salivary OT and oxy-Hb signal. Furthermore, while holding their infants, high-OT fathers showed left hemispheric dominance compared to low-OT fathers, while high-OT mothers showed right hemispheric dominance compared to low-OT mothers. This study showed that fathers with high-OT levels showed neural activation with left hemispheric dominance, while holding their infants, suggesting that increase of OT level might activate paternal PFC related to parenting behavior, although the same is not true for mothers.

  10. Effect of different doses of oxytocin on cardiac electrophysiology and arrhythmias induced by ischemia.

    Science.gov (United States)

    Houshmand, Fariba; Faghihi, Mahdieh; Imani, Alireza; Kheiri, Soleiman

    2017-01-01

    The onset of acute myocardial ischemia (MI) is accompanied by a rapid increase in electrical instability and often fatal ventricular arrhythmias. This study investigated that whether oxytocin (OT) can modulate ischemia-induced arrhythmias and considered relationships between the severity of arrhythmia and the electrocardiogram parameters during ischemia. OT (0.0001-1 μg) was administrated intraperitoneally 30 min before ischemia. To examine receptor involved, a selective OT-receptor antagonist, atosiban (ATO), was infused 10 min before OT. OT caused a significant and biphasic dose-dependent reduction in ectopic heart activity and arrhythmia score. OT doses that reduced ventricular arrhythmia elicited significant increase in QT interval. OT attenuated the electrophysiological changes associated with MI and there was significant direct relationship between QRS duration and arrhythmia score. ATO treatment reduced beneficial effects of OT on arrhythmogenesis. Nevertheless, ATO failed to alter OT effects on premature ventricular contractions. We assume that the ability of OT to modulate the electrical activity of the heart may play an important role in the antiarrhythmic actions of OT.

  11. Effect of different doses of oxytocin on cardiac electrophysiology and arrhythmias induced by ischemia

    Directory of Open Access Journals (Sweden)

    Fariba Houshmand

    2017-01-01

    Full Text Available The onset of acute myocardial ischemia (MI is accompanied by a rapid increase in electrical instability and often fatal ventricular arrhythmias. This study investigated that whether oxytocin (OT can modulate ischemia-induced arrhythmias and considered relationships between the severity of arrhythmia and the electrocardiogram parameters during ischemia. OT (0.0001–1 μg was administrated intraperitoneally 30 min before ischemia. To examine receptor involved, a selective OT-receptor antagonist, atosiban (ATO, was infused 10 min before OT. OT caused a significant and biphasic dose-dependent reduction in ectopic heart activity and arrhythmia score. OT doses that reduced ventricular arrhythmia elicited significant increase in QT interval. OT attenuated the electrophysiological changes associated with MI and there was significant direct relationship between QRS duration and arrhythmia score. ATO treatment reduced beneficial effects of OT on arrhythmogenesis. Nevertheless, ATO failed to alter OT effects on premature ventricular contractions. We assume that the ability of OT to modulate the electrical activity of the heart may play an important role in the antiarrhythmic actions of OT.

  12. Oxytocin as a novel therapeutic option for type I diabetes and diabetic osteopathy.

    Science.gov (United States)

    Elabd, S K; Sabry, I; Mohasseb, M; Algendy, A

    2014-04-01

    The aim of the present study was to highlight the newly discovered metabolic role of oxytocin (OT) in the type I diabetic rats. Previous studies have demonstrated that OT has a beneficial role on bone physiology and therefore, the OT effect on the diabetic osteopathy will be assessed as well. Induction of the type I diabetes was carried out by an intraperitoneal injection of 60 mg/kg body weight of streptozotocin. The metabolic role of OT on diabetic rats after OT treatment with intramuscular injection of 40 µIU/kg body weight for 6 weeks was assessed. Histological and ultrastructural studies of rat pancreas samples, before and after the OT injection, were performed and compared with the obtained physiological results. Oxytocin treatment had positive metabolic effects in diabetic rats. This is based on the change in glucose metabolism, lipid profile, and insulin sensitivity in experimental animals. In addition, OT treatment showed histological regenerative changes of pancreatic islet cells of diabetic rats. Moreover, OT administration showed that it has an anabolic effect on the bone biology. The results suggest that activation of the oxytocin receptor (OTR) pathway by infusion of OT, OT analogs, or OT agonists may represent a promising approach for the treatment of diabetes and some of its complications, including diabetic osteopathy.

  13. CSF and blood oxytocin concentration changes following intranasal delivery in macaque.

    Directory of Open Access Journals (Sweden)

    Olga Dal Monte

    Full Text Available Oxytocin (OT in the central nervous system (CNS influences social cognition and behavior, making it a candidate for treating clinical disorders such as schizophrenia and autism. Intranasal administration has been proposed as a possible route of delivery to the CNS for molecules like OT. While intranasal administration of OT influences social cognition and behavior, it is not well established whether this is an effective means for delivering OT to CNS targets. We administered OT or its vehicle (saline to 15 primates (Macaca mulatta, using either intranasal spray or a nebulizer, and measured OT concentration changes in the cerebral spinal fluid (CSF and in blood. All subjects received both delivery methods and both drug conditions. Baseline samples of blood and CSF were taken immediately before drug administration. Blood was collected every 10 minutes after administration for 40 minutes and CSF was collected once post-delivery, at the 40 minutes time point. We found that intranasal administration of exogenous OT increased concentrations in both CSF and plasma compared to saline. Both delivery methods resulted in similar elevations of OT concentration in CSF, while the changes in plasma OT concentration were greater after nasal spray compared to nebulizer. In conclusion our study provides evidence that both nebulizer and nasal spray OT administration can elevate CSF OT levels.

  14. Oxytocin and vasopressin flatten dominance hierarchy and enhance behavioral synchrony in part via anterior cingulate cortex.

    Science.gov (United States)

    Jiang, Yaoguang; Platt, Michael L

    2018-05-29

    The neuropeptides oxytocin (OT) and arginine vasopressin (AVP) influence social functions in many mammals. In humans and rhesus macaques, OT delivered intranasally can promote prosocial behavior in certain contexts. Yet the precise neural mechanisms mediating these behavioral effects remain unclear. Here we show that treating a group of male macaque monkeys intranasally with aerosolized OT relaxes their spontaneous social interactions with other monkeys. OT reduces differences in social behavior between dominant and subordinate monkeys, thereby flattening the status hierarchy. OT also increases behavioral synchrony within a pair. Intranasal delivery of aerosolized AVP reproduces the effects of OT with greater efficacy. Remarkably, all behavioral effects are replicated when OT or AVP is injected focally into the anterior cingulate gyrus (ACCg), a brain area linked to empathy and other-regarding behavior. ACCg lacks OT receptors but is rich in AVP receptors, suggesting exogenous OT may shape social behavior, in part, via nonspecific binding. Notably, OT and AVP alter behaviors of both the treated monkey and his untreated partner, consistent with enhanced feedback through reciprocal social interactions. These findings bear important implications for use of OT in both basic research and as a therapy for social impairments in neurodevelopmental disorders.

  15. Detection of Tropical Overshooting Cloud Tops Using Himawari-8 Imagery

    Directory of Open Access Journals (Sweden)

    Miae Kim

    2017-07-01

    Full Text Available Abstract: Overshooting convective cloud Top (OT-accompanied clouds can cause severe weather conditions, such as lightning, strong winds, and heavy rainfall. The distribution and behavior of OTs can affect regional and global climate systems. In this paper, we propose a new approach for OT detection by using machine learning methods with multiple infrared images and their derived features. Himawari-8 satellite images were used as the main input data, and binary detection (OT or nonOT with class probability was the output of the machine learning models. Three machine learning techniques—random forest (RF, extremely randomized trees (ERT, and logistic regression (LR—were used to develop OT classification models to distinguish OT from non-OT. The hindcast validation over the Southeast Asia and West Pacific regions showed that RF performed best, resulting in a mean probabilities of detection (POD of 77.06% and a mean false alarm ratio (FAR of 36.13%. Brightness temperature at 11.2 μm (Tb11 and its standard deviation (STD in a 3 × 3 window size were identified as the most contributing variables for discriminating OT and nonOT classes. The proposed machine learning-based OT detection algorithms produced promising results comparable to or even better than the existing approaches, which are the infrared window (IRW-texture and water vapor (WV minus IRW brightness temperature difference (BTD methods.

  16. Salivary Oxytocin Concentrations in Males following Intranasal Administration of Oxytocin: A Double-Blind, Cross-Over Study.

    Science.gov (United States)

    Daughters, Katie; Manstead, Antony S R; Hubble, Kelly; Rees, Aled; Thapar, Anita; van Goozen, Stephanie H M

    2015-01-01

    The use of intranasal oxytocin (OT) in research has become increasingly important over the past decade. Although researchers have acknowledged a need for further investigation of the physiological effects of intranasal administration, few studies have actually done so. In the present double-blind cross-over study we investigated the longevity of a single 24 IU dose of intranasal OT measured in saliva in 40 healthy adult males. Salivary OT concentrations were significantly higher in the OT condition, compared to placebo. This significant difference lasted until the end of testing, approximately 108 minutes after administration, and peaked at 30 minutes. Results showed significant individual differences in response to intranasal OT administration. To our knowledge this is the largest and first all-male within-subjects design study to demonstrate the impact of intranasal OT on salivary OT concentrations. The results are consistent with previous research in suggesting that salivary OT is a valid matrix for OT measurement. The results also suggest that the post-administration 'wait-time' prior to starting experimental tasks could be reduced to 30 minutes, from the 45 minutes typically used, thereby enabling testing during peak OT concentrations. Further research is needed to ascertain whether OT concentrations after intranasal administration follow similar patterns in females, and different age groups.

  17. Salivary Oxytocin Concentrations in Males following Intranasal Administration of Oxytocin: A Double-Blind, Cross-Over Study.

    Directory of Open Access Journals (Sweden)

    Katie Daughters

    Full Text Available The use of intranasal oxytocin (OT in research has become increasingly important over the past decade. Although researchers have acknowledged a need for further investigation of the physiological effects of intranasal administration, few studies have actually done so. In the present double-blind cross-over study we investigated the longevity of a single 24 IU dose of intranasal OT measured in saliva in 40 healthy adult males. Salivary OT concentrations were significantly higher in the OT condition, compared to placebo. This significant difference lasted until the end of testing, approximately 108 minutes after administration, and peaked at 30 minutes. Results showed significant individual differences in response to intranasal OT administration. To our knowledge this is the largest and first all-male within-subjects design study to demonstrate the impact of intranasal OT on salivary OT concentrations. The results are consistent with previous research in suggesting that salivary OT is a valid matrix for OT measurement. The results also suggest that the post-administration 'wait-time' prior to starting experimental tasks could be reduced to 30 minutes, from the 45 minutes typically used, thereby enabling testing during peak OT concentrations. Further research is needed to ascertain whether OT concentrations after intranasal administration follow similar patterns in females, and different age groups.

  18. Oxytocin--its role in male reproduction and new potential therapeutic uses.

    Science.gov (United States)

    Thackare, Hemlata; Nicholson, Helen D; Whittington, Kate

    2006-01-01

    Oxytocin (OT) is traditionally thought of as a "female" neurohypophysis hormone due to its role in parturition and milk ejection. However, OT is recognized as having endocrine and paracrine roles in male reproduction. At ejaculation, a burst of OT is released from the neurohypophysis into the systemic circulation and stimulates contractions of the reproductive tract aiding sperm release. There is conclusive evidence that OT is synthesized within the mammalian testis, epididymis and prostate and the presence of OT receptors (OTRs) through the reproductive tract supports a local action for this peptide. OT has a paracrine role in stimulating contractility of the seminiferous tubules, epididymis and the prostate gland. Interestingly, OT has also been shown to modulate androgen levels in these tissues via stimulation of the conversion of testosterone to dihydrotestostone (DHT) by 5alpha-reductase. The elucidation of OT's role in male reproduction has suggested a number of potential therapeutic uses for this hormone. Exogenous administration of OT has, in some cases, been shown to increase the numbers of ejaculated sperm, possibly by stimulating contractions of the reproductive tract and thus aiding sperm passage. Within the prostate, OT has been shown to affect gland growth both directly and via its interaction with androgen metabolism. Prostate pathologies due to unregulated cell proliferation/growth, such as benign prostatic hyperplasia and cancer, are unfortunately very common and few effective treatments are available. Greater understanding of paracrine growth mediators, such as OT, is likely to provide new mechanisms for treating such pathologies.

  19. Role of oxytocin in improving the welfare of farm animals - A review.

    Science.gov (United States)

    Chen, Siyu; Sato, Shusuke

    2017-04-01

    Recently, increasing attention has been paid to the welfare of farm animals, which have been evaluated using behavioral and physiological measures. However, so far, the measures have almost always been used to estimate poor welfare. In this review, firstly we focus on how oxytocin (OT) relates to positive social behavior, pleasure, and stress tolerance, and second on which management factors stimulate OT release. OT induces maternal and affiliative behaviors and has an anti-stress effect. Further, OT is produced during enjoyable events, and has positive feedback on its own release as well. Therefore, to some extent, the relationship of OT to positive normal behavior was mutually beneficial-heightened OT concentration owing to comfortable rearing conditions induces positive social behavior, which in turn may increase OT concentration. Hence, studies on animal welfare should pay more attention to increasing comfort and the stress tolerance, rather than only focusing on when stress occurs in farm animals.

  20. Vasopressin and Oxytocin Reduce Food Sharing Behavior in Male, but Not Female Marmosets in Family Groups

    Directory of Open Access Journals (Sweden)

    Jack H. Taylor

    2017-07-01

    Full Text Available Oxytocin (OT is critical for lactation and maternal care, but OT and the related nonapeptide vasopressin are important for caregiving behaviors in fathers and alloparents as well. This experiment tested the effects of vasopressin and OT on food sharing in marmoset families. We treated caregivers (parents, siblings with intranasal vasopressin, OT, or saline, and then paired them with the youngest marmoset in the family. Caregivers were given preferred food, and then observed for food sharing and aggressive behavior with young marmosets. OT reduced food sharing from male alloparents to youngest siblings, and fathers that received vasopressin refused to share food with their youngest offspring more often than when treated with OT. Vasopressin increased aggressive vocalizations directed toward potential food recipients in all classes of caregivers. These results indicate that vasopressin and OT do not always enhance prosocial behavior: modulation of food sharing depends on both sex and parental status.

  1. Dissociating frontal regions that co-lateralize with different ventral occipitotemporal regions during word processing☆

    Science.gov (United States)

    Seghier, Mohamed L.; Price, Cathy J.

    2013-01-01

    The ventral occipitotemporal sulcus (vOT) sustains strong interactions with the inferior frontal cortex during word processing. Consequently, activation in both regions co-lateralize towards the same hemisphere in healthy subjects. Because the determinants of lateralisation differ across posterior, middle and anterior vOT subregions, we investigated whether lateralisation in different inferior frontal regions would co-vary with lateralisation in the three different vOT subregions. A whole brain analysis found that, during semantic decisions on written words, laterality covaried in (1) posterior vOT and the precentral gyrus; (2) middle vOT and the pars opercularis, pars triangularis, and supramarginal gyrus; and (3) anterior vOT and the pars orbitalis, middle frontal gyrus and thalamus. These findings increase the spatial resolution of our understanding of how vOT interacts with other brain areas during semantic categorisation on words. PMID:23728081

  2. Central oxytocin and food intake: focus on macronutrient-driven reward

    Directory of Open Access Journals (Sweden)

    Anica eKlockars

    2015-04-01

    Full Text Available Centrally acting oxytocin (OT is known to terminate food consumption in response to excessive stomach distension, increase in salt loading and presence of toxins. Hypothalamic-hindbrain OT pathways facilitate these aspects of OT-induced hypophagia. However, recent discoveries have implicated OT in modifications of feeding via reward circuits: OT has been found to differentially affect consumption of individual macronutrients in choice and no-choice paradigms. In this mini-review, we focus on presenting and interpreting evidence that defines OT as a key component of mechanisms that reduce eating for pleasure and shape macronutrient preferences. We also provide remarks on challenges in integrating the knowledge on physiological and pathophysiological states in which both OT activity and macronutrient preferences are affected.

  3. Developmental toxicity of organotin compounds in animals

    Directory of Open Access Journals (Sweden)

    Lijiao eWu

    2014-09-01

    Full Text Available Organotin compounds (OTs have been used as biocides in antifouling paints and agriculture. The IMO introduced a global ban on the use of OTs in antifouling systems in 2001 due to their high toxicity. However, OTs have still been detected in the environment and pose a threat to the ecosystem. Several research groups have summarized the analytical methods, environmental fate, biochemistry, reproductive toxicity and mechanisms of actions of OTs. Here, we reviewed the developmental toxicity of OTs in various organisms such as sea urchin, ascidian, mussel and fish. The differences in sensitivity to OT exposure exist not only in different species but also at different stages in the same species. Though some hypotheses have been proposed to explain the developmental toxicity of OTs, the solid evidences are greatly in need.

  4. Neuropeptide diversity and the regulation of social behavior in New World primates

    Science.gov (United States)

    French, Jeffrey A.; Taylor, Jack H.; Mustoe, Aaryn C.; Cavanaugh, Jon

    2016-01-01

    Oxytocin (OT) and vasopressin (AVP) are important hypothalamic neuropeptides that regulate peripheral physiology, and have emerged as important modulators of brain function, particularly in the social realm. OT structure and the genes that ultimately determine structure are highly conserved among diverse eutherian mammals, but recent discoveries have identified surprising variability in OT and peptide structure in New World monkeys (NWM), with five new OT variants identified to date. This review explores these new findings in light of comparative OT/AVP ligand evolution, documents coevolutionary changes in the oxytocin and vasopressin receptors (OTR and V1aR), and highlights the distribution of neuropeptidergic neurons and receptors in the primate brain. Finally, the behavioral consequences of OT and AVP in regulating NWM sociality are summarized, demonstrating important neuromodulatory effects of these compounds and OT ligand-specific influences in certain social domains. PMID:27020799

  5. The acute effects of intranasal oxytocin administration on endocrine and sexual function in males.

    Science.gov (United States)

    Burri, Andrea; Heinrichs, Markus; Schedlowski, Manfred; Kruger, Tillmann H C

    2008-06-01

    The role of the neuropeptide oxytocin (OT) ranges from the modulation of neuroendocrine physiological effects to the establishment of complex social and bonding behaviours. Experimental studies in animals, as well as case reports in humans, suggest that OT affects different aspects of sexual behaviour and has predominantly facilitating properties for sexual appetence and performance. Using a previously established experimental paradigm of sexual arousal and masturbation-induced orgasm, this study investigated the acute effects of intranasal OT application (24I.U.) on endocrine parameters and measures of sexual appetence and function in healthy men (n=10). In a double-blind, placebo-controlled, balanced cross-over design, sexual arousal, and orgasm were induced by an erotic film and masturbation. In addition to the continuous recording of endocrine (OT, cortisol, prolactin, epinephrine, norepinephrine) and cardiovascular data (heart rate), parameters of appetitive, consummatory, and refractory sexual behaviour were assessed using the acute sexual experience scale (ASES). OT plasma levels were significantly elevated after intranasal OT throughout the whole experiment (>60 min). In addition, OT treatment induced significantly higher increases in epinephrine plasma levels during sexual activity without affecting cortisol levels, prolactin levels or heart rate. OT treatment did not alter appetitive, consummatory, and refractory sexual behaviour according to the ASES. However, when subjects were asked about their subjective perception of whether OT or placebo had been applied, eight out of 10 subjects in the OT group answered correctly, thus pointing to an altered perception of arousal. In conclusion, intranasally administered OT leads to a marked increase in OT plasma levels together with increased secretion of catecholamines when subjects are engaged in sexual activity in a laboratory setting. As the effects of OT on sexual behaviour were equivocal, future studies

  6. Distinct BOLD activation profiles following central and peripheral oxytocin administration in awake rats

    Directory of Open Access Journals (Sweden)

    Craig F Ferris

    2015-09-01

    Full Text Available A growing body of literature has suggested that intranasal oxytocin (OT or other systemic routes of administration can alter prosocial behavior, presumably by directly activating OT sensitive neural circuits in the brain. Yet there is no clear evidence that OT given peripherally can cross the blood-brain-barrier at levels sufficient to engage the OT receptor. To address this issue we examined changes in blood oxygen level dependent (BOLD signal intensity in response to peripheral OT injections (0.1, 0.5 or 2.5 mg/kg during functional magnetic resonance (fMRI in awake rats imaged at 7.0 tesla. These data were compared to OT (1ug/5 µl given directly to the brain via the lateral cerebroventricle. Using a 3D annotated MRI atlas of the rat brain segmented into 171 brain areas and computational analysis we reconstructed the distributed integrated neural circuits identified with BOLD fMRI following central and peripheral OT. Both routes of administration caused significant changes in BOLD signal within the first 10 min of administration. As expected, central OT activated a majority of brain areas known to express a high density of OT receptors e.g., lateral septum, subiculum, shell of the accumbens, bed nucleus of the stria terminalis. This profile of activation was not matched by peripheral OT. The change in BOLD signal to peripheral OT did not show any discernible dose-response. Interestingly, peripheral OT affected all subdivisions of the olfactory bulb, in addition to the cerebellum and several brainstem areas relevant to the autonomic nervous system, including the solitary tract nucleus. The results from this imaging study do not support a direct central action of peripheral OT on the brain. Instead, the patterns of brain activity suggest that peripheral OT may interact at the level of the olfactory bulb and through sensory afferents from the autonomic nervous system to influence brain activity.

  7. Operating theatre ventilation systems and microbial air contamination in total joint replacement surgery: results of the GISIO-ISChIA study.

    Science.gov (United States)

    Agodi, A; Auxilia, F; Barchitta, M; Cristina, M L; D'Alessandro, D; Mura, I; Nobile, M; Pasquarella, C

    2015-07-01

    Recent studies have shown a higher rate of surgical site infections in hip prosthesis implantation using unidirectional airflow ventilation compared with turbulent ventilation. However, these studies did not measure the air microbial quality of operating theatres (OTs), and assumed it to be compliant with the recommended standards for this ventilation technique. To evaluate airborne microbial contamination in OTs during hip and knee replacement surgery, and compare the findings with values recommended for joint replacement surgery. Air samplings were performed in 28 OTs supplied with unidirectional, turbulent and mixed airflow ventilation. Samples were collected using passive sampling to determine the index of microbial air contamination (IMA). Active sampling was also performed in some of the OTs. The average number of people in the OT and the number of door openings during the sampling period were recorded. In total, 1228 elective prosthesis procedures (60.1% hip and 39.9% knee) were included in this study. Of passive samplings performed during surgical activity in unidirectional airflow ventilation OTs (U-OTs) and mixed airflow OTs (M-OTs), 58.9% and 87.6% had IMA values >2, respectively. Of samplings performed during surgical activity in turbulent airflow OTs (T-OTs) and in turbulent airflow OTs with the surgical team wearing Steri-Shield Turbo Helmets (TH-OTs), 8.6% and 60% had IMA values ≤ 2, respectively. Positive correlation was found between IMA values and the number of people in the OT and the number of door openings (P systems always provide acceptable airborne bacterial counts. Copyright © 2015 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.

  8. Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats

    Science.gov (United States)

    Hicks, C; Ramos, L; Reekie, T; Misagh, G H; Narlawar, R; Kassiou, M; McGregor, I S

    2014-01-01

    Background and Purpose There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be constrained by peripheral autonomic effects, which may involve an action at both OT and vasopressin V1A receptors. Here, we characterized the cardiovascular and thermoregulatory effects of OT, vasopressin (AVP) and the non-peptide OT receptor agonist WAY 267,464 in rats, and assessed the relative involvement of the OT and V1A receptors in these effects. Experimental Approach Biotelemetry in freely moving male Wistar rats was used to examine body temperature and heart rate after OT (0.01 – 1 mg kg−1; i.p.), AVP (0.001 – 0.1 mg kg−1; i.p.) or WAY 267,464 (10 and 100 mg kg−1; i.p.). The actions of the OT receptor antagonist Compound 25 (C25, 5 and 10 mg kg−1) and V1A receptor antagonist SR49059 (1 and 10 mg kg−1) were studied, as well as possible V1A receptor antagonist effects of WAY 267,464. Key Results OT and AVP dose-dependently reduced body temperature and heart rate. WAY 267,464 had similar, but more modest, effects. SR49059, but not C25, prevented the hypothermia and bradycardia induced by OT and AVP. WAY 267,464 (100 mg·kg−1) prevented the effects of OT, and to some extent AVP. Conclusions and Implications Peripherally administered OT and AVP have profound cardiovascular and thermoregulatory effects that appear to principally involve the V1A receptor rather than the OT receptor. Additionally, WAY 267,464 is not a simple OT receptor agonist, as it has functionally relevant V1A antagonist actions. PMID:24641248

  9. Body temperature and cardiac changes induced by peripherally administered oxytocin, vasopressin and the non-peptide oxytocin receptor agonist WAY 267,464: a biotelemetry study in rats.

    Science.gov (United States)

    Hicks, C; Ramos, L; Reekie, T; Misagh, G H; Narlawar, R; Kassiou, M; McGregor, I S

    2014-06-01

    There is current interest in oxytocin (OT) as a possible therapeutic in psychiatric disorders. However, the usefulness of OT may be constrained by peripheral autonomic effects, which may involve an action at both OT and vasopressin V1A receptors. Here, we characterized the cardiovascular and thermoregulatory effects of OT, vasopressin (AVP) and the non-peptide OT receptor agonist WAY 267,464 in rats, and assessed the relative involvement of the OT and V1A receptors in these effects. Biotelemetry in freely moving male Wistar rats was used to examine body temperature and heart rate after OT (0.01 - 1 mg kg(-1); i.p.), AVP (0.001 - 0.1 mg kg(-1); i.p.) or WAY 267,464 (10 and 100 mg kg(-1); i.p.). The actions of the OT receptor antagonist Compound 25 (C25, 5 and 10 mg kg(-1)) and V1A receptor antagonist SR49059 (1 and 10 mg kg(-1)) were studied, as well as possible V1A receptor antagonist effects of WAY 267,464. OT and AVP dose-dependently reduced body temperature and heart rate. WAY 267,464 had similar, but more modest, effects. SR49059, but not C25, prevented the hypothermia and bradycardia induced by OT and AVP. WAY 267,464 (100 mg·kg(-1)) prevented the effects of OT, and to some extent AVP. Peripherally administered OT and AVP have profound cardiovascular and thermoregulatory effects that appear to principally involve the V1A receptor rather than the OT receptor. Additionally, WAY 267,464 is not a simple OT receptor agonist, as it has functionally relevant V1A antagonist actions. © 2014 The British Pharmacological Society.

  10. Aktuální otázky používání zahraničního práva v soudním a rozhodčím řízení

    Czech Academy of Sciences Publication Activity Database

    Pauknerová, Monika

    2012-01-01

    Roč. 151, č. 12 (2012), s. 1265-1290 ISSN 0231-6625 Institutional support: RVO:68378122 Keywords : private international law * treatment of foreign law * arbitral proceedings Subject RIV: AG - Legal Sciences

  11. Přehled kulturních, literárních a školních otázek aneb Svědectví o vkladu české menšiny v Chorvatsku do české a chorvatské vědy

    Czech Academy of Sciences Publication Activity Database

    Pánek, Jaroslav

    2017-01-01

    Roč. 35, č. 1 (2017), s. 97-109 ISSN 1330-3880 Institutional support: RVO:67985963 Keywords : Czech Minorities * Croatia * Sciences Subject RIV: AB - History OBOR OECD: History (history of science and technology to be 6.3, history of specific sciences to be under the respective headings)

  12. Conolly, R.B., Ankley, G.T., Cheng, WY., Mayo, M.L., Miller, D.H., Perkins, E.J., Villeneuve, D.L., and Watanable, K.H. (2017). Quantitative adverse outcome pathways and their application ot predictive toxicology. Environ. Sci. Technol. 51, 4661–4672

    Data.gov (United States)

    U.S. Environmental Protection Agency — A publised mansucript describing a quantitative adverse outcome pathway (qAOP) and its relevance to risk assessment. This dataset is not publicly accessible because:...

  13. Nezájem pověřených. Přístup českých politiků a političek, úředníků a úřednic k otázkám genderové rovnosti

    Czech Academy of Sciences Publication Activity Database

    Křížková, Alena

    2006-01-01

    Roč. 7, č. 2 (2006), s. 37-41 ISSN 1213-0028 R&D Projects: GA AV ČR 1QS700280503 Institutional research plan: CEZ:AV0Z70280505 Keywords : gender equality legislation * EU Eastern enlargement * attitudes of officals and politicians to gender issues Subject RIV: AO - Sociology, Demography http://www. gender online.cz

  14. Středoevropské bezlesí v čase a prostoru. V. Otázka přirozeného bezlesí v českých zemích a na Slovensku

    Czech Academy of Sciences Publication Activity Database

    Ložek, Vojen

    2004-01-01

    Roč. 59, č. 6 (2004), s. 169-175 ISSN 1210-258X Institutional research plan: CEZ:AV0Z3013912 Keywords : Woodland * Open Country * Human Impact Subject RIV: DB - Geology ; Mineralogy http://www.casopis.ochranaprirody.cz/res/data/003/000467.pdf

  15. Organization of measures on protection of population and territories against weapons of mass destruction: brief analysis of laboratory control and conditions of personnel protective means of respiratory organs in the Republic of Tajikistan; Organizatsiya meropriyatiy po zashite naseleniya i territoriy ot oruzhiya massovogo unichtozheniya; kratkiy analiz laborotornogo kotrolya i sostoyaniya sredstv individual'noy zashiti organov dikhaniya v Respublike Tadzhikistan

    Energy Technology Data Exchange (ETDEWEB)

    Kamalov, D. D.; Makhmadov, T. F.; Stotskiy, D. F. [Committee of Emergency Situations and Civil Defence under the Government of the Republic of Tajikistan, Dushanbe (Tajikistan)

    2010-07-01

    Full text: Changing of character of acts of terrorism in the end of 20 and the beginning of 21 centuries specifies the increased interest of the terrorist organizations to the weapons of mass destruction. The most accessible are the biological and chemical weapons, as well as the self-made {sup d}irty{sup e}xplosive devices filled with a radioactive material. Application by terrorists of the nuclear weapon at the present is not actual. A nuclear ammunition is under the intensive control not only of the state-possessor of the nuclear weapon, but also all world community. Benefit of use of mass destruction weapons by the terrorist organizations is depended of accessibility of combat chemical or biological substances, easiness of their manufacture, a small amount of poisoning and biological substances necessary for use in the closed space, availability of influence on the big areas, psychological pressure upon the world community. The most known incidents related with use of chemical or biological substances were: - 1992 (chemical) - neo nazis attacked synagogue using cyanide, Germany - 1993 (chemical) - cyanide inside the bomb exploded in the World Trade Center, USA - 1994 (chemical) - use of sarin in Matsumoto, Japan led to the death of 8 and hospitalization of 200 people - 1995 (chemical) - again sarin used in Tokyo metro, 12 people died and 5 500 injured - 1995 (chemical) - FBI agents prevented the attack with the use of sarin of Disney land - 1995 (chemical) - attack in Japan with use of cyanide, phosgene and pepper gas - 1995 (biological) - a member of 'Aryan nation' was arrested for ordering a pestilence virus. - 1995 (radiological) - a terrorist organization of Chechnya republic placed a 14 kilo pack filled with a radioactive cesium-137 and explosives in a Moscow park - 1997 (chemical) - 2 attacks of the trading centers with a use of chlor bombs in Japan. The facts mentioned above put before the Republic of Tajikistan objectives of organization of actions for population and territory protection from mass-destruction weapon. Organization of actions on population and territory protection is caused on geographical location of Tajikistan. There is a number of some states near Tajikistan that have nuclear weapon: India, China, Pakistan. The basic actions for protection of the population and territories from weapons of mass destruction are: maintenance and accumulation of means of an individual defense, creation of stocks; creation and restoration of protective constructions of a civil defense; evacuation actions planning; restoration of system of monitoring and the laboratory control of a civil defense of Republic Tajikistan; according to the Government Regulation N 527 and dated on 31{sup st} of October, 2008 the 'Emergency situations and civil defense system development 2009-2014' Program was adopted. According to the Plan of the events within this Programme Committee of emergency situations and civil defense under the Government of Republic of Tajikistan provides a stage-by-stage realization of the actions for protection of population and territories from mass-destruction weapon. One of the important actions is provision and accumulation of the means of personal protection, keeping of this means. The means of personal protections are laboratory tested by the specialists of the Committee of emergency situations and civil defense. Analytical data of the Committee of emergency situations and civil defense allows making some conclusions concerning experienced storage of the means of personal protection. A general analysis of laboratory test indicates that: laboratory tests of filtering boxes indicate the preservation of air flow resistance and waterproof due to the adherence to the rules of keeping; laboratory tests of the front parts of the gas masks and their hardness and waterproof, and the waterproof of the valves show that the front part is dependent on meteorological character of the region of storage at long-term keeping. Conclusions: According to the experience, personal protection equipment kept due to the rules of storage can keep its technical characteristics.

  16. Riigivõimu ülesannete üleandmine eraõiguslikele isikutele vabakutseliste kohtutäiturite näitel : [bakalaureusetöö] / Elin Palts ; Tartu Ülikooli Õigusinstituut ; juhendajad: Jaanus Ots, Kaire Pikamäe

    Index Scriptorium Estoniae

    Palts, Elin

    2003-01-01

    Avaliku halduse reformi mõiste, avalike ülesannete eraõiguslikele isikutele üleandmise erinevad mudelid, täitevsüsteemi reform, avalik-õiguslike nõuete jaotamine kohtutäiturite vahel, lisateenuste osutamine kohtutäiturite poolt

  17. Copolymerization of Ethylene Induced by Cobalt-60 Gamma Radiation; Copolymerisation de l'ethylene induite par des rayons gamma du cobalt-60; Sopolimerizatsiya ehtilena pod dejstviem gamma-izlucheniya ot istochnika ks'yali-60; Copolimerizacion del etileno inducida por las radiaciones gamma del cobalto-60

    Energy Technology Data Exchange (ETDEWEB)

    Steinberg, M.; Colombo, P. [Brookhaven National Laboratory, Long Island, NY (United States)

    1963-11-15

    The gamma radiation initiated copolymerization of ethylene with a number of different monomers was studied at 20{sup o}C and initial pressures up to 680 atm. The experiments were conducted statically in two-phase systems with the exception of the ethylene-carbon monoxide system. Isolation of the copolymers was effected by solvent extraction and fractional precipitation techniques. Infra-red spectroscopy was used for identification. The composition was determined by elemental analysis. A partial evaluation of some of the reaction products including crystalline melting points, densities, solubility characteristics, and molecular weights are given. Evidence of ethylene copolymerization was established with each of the following monomers: styrene, methyl methacrylate, vinyl acetate, acrylonitrile, allyl acetate, isobutylene, chlorotrifluoroethylene, trans 2-butene, methyl acrylate, isoprene, propylene, vinyl chloride, 1-butene, cis 2-butene, carbon monoxide, vinyl pyrrolidone, methyl vinyl ketone, and divinyl benzene. The experimental data obtained in the study of the ethylene-carbon monoxide system were found to obey a linear form of the copolymer composition equation. The ratio of specific rate constants for carbon monoxide and ethylene ({alpha}) was found to have a value of 22.0, indicating that carbon monoxide as a monomer, is activated to the extent that it adds 22 times as fast as an ethylene monomer to an ethylene free-radical chain end. Explosive decomposition was observed to occur during irradiation of ethylene arid chlorotrifluoroethylene under certain irradiation conditions. There is an indication that a threshold radiation intensity exists which induces this violent reaction. The unique advantage of cobalt-60 gamma radiation is that it can be used to induce and control ethylene copolymerization reactions at low temperatures. (author) [French] La copolymerisation de l'ethylene avec divers monomeres provoquee avec des rayons gamma a ete etudiee a 20{sup o}C et a des pressions initiales allant jusqu'a 680 atm. On a procede aux experiences, en milieu statique, dans des systemes a deux phases, a l'exception du systeme ethylene-oxyde de carbone. La separation des copolymeres a ete obtenue par des methodes d'extraction par solvant et de precipitation fractionnee. L'identification a ete faite au moyen de la spectroscopic aux infrarouges. La composition a ete determinee par analyse elementaire. Les auteurs donnent une evaluation partielle de certains produits de la reaction, y compris les points de fusion cristalline, les densites, les caracteristiques de solubilite et les poids moleculaires. La copolymerisation de l'ethylene a ete etablie avec chacun des monomeres suivants : styrene, methacrylate de methyle, acetate de vinyle, acrylonitrile, acetate d'allyle, isobutylene, chlorotiifluoroethylene, transbutene-2, acrylate de methyle, isoprene, propylene, chlorure de vinyle, butene-1, cis-butene-2, oxyde de carbone, pyrrolidone de vinyle, methyle- vinyle-cetone et divinyle-benzene. Les auteurs ont trouve que les donnees experimentales obtenues dans l'etude du systeme ethylene-oxyde de carbone suivaient une forme lineaire de l'equation de composition du copolymere. Pour le rapport {alpha} des constantes de vitesse specifiques de l'oxyde de carbone et de l'ethylene, ils ont determine la valeur 22,0, ce qui montre que l'oxyde de carbone en tant que monomere est active a tel point qu'il se fixe a l'extremite d'une chaftie de radicaux libres d'ethylene 22 fois plus vite que ne le fait un monomere d'ethylene. (author) [Spanish] Los autores estudiaron la copolimerizacion del etileno, inducida por las radiaciones gamma, con una serie de diversos monometos, a 20{sup o}C y presiones iniciales de hasta 680 atm. Los experimentos se llevaron a cabo estaticamente en sistemas bifasicos, salvo en el caso del etileno-oxido de carbono. La separacion de los copolimeros se llevo a cabo por extraccion mediante disolventes y por precipitacion fraccionada. La identificacion se efectuo por espectroscopia infrarroja y la composicion se determino por analisis elemental. Para algunos de los productos de reaccion, los autores indican los puntos de fusion cristalinos, las densidades, las caracteristicas de solubilidad y los pesos moleculares. Obtuvieron pruebas de la copolimerizacion del etileno con cada uno de los siguientes monomeros: estireno, metacrilato de metilo, acetato de vinilo, acrilonitrilo, acetato de alilo, isobuteno, clorotrifluoretileno, trans 2-buteno, acrilato de metilo, isopreno, propeno, cloruro de vinilo, 1-buteno, cis 2-buteno, oxido de carbono, vinilpirrolidona, metilvinilcetona y divinilbenceno. Comprobaron que los datos experimentales obtenidos en el estudio del sistema etileno-oxido de carbono responden a una forma lineal de la ecuacion de composicion del copolimero. Encontraron el valor 22,0 para la razon ({alpha}) de las constantes de velocidad especificas correspondientes al oxido de carbono y al etileno, respectivamente, lo que indica que en calidad de monomero el oxido de carbono se activa en tal medida que se fija al extremo de una cadena de radical etilenico libre con una velocidad 22 veces mayor que un monomero etilenico. (author) [Russian] Byla izuchen vyzvannaya gamma-izlucheniem sopolimerizatsiya ehtilena s ryadom razlichnykh monomerov pri temperature 20{sup o}C i pri nachal'nykh davleniyakh do 680 atm. Ehksperimenty provodilis' staticheski v dvukhfaznykh sistemakh, za isklyucheniem sistemy ehtilen-okis' ugleroda. Razdelenie sopolimerov proizvodilos' metodami ehkstraktsii rastvoritelem i fraktsionirovannogo osazhdeniya. Dlya identifikatsii ispol'zovali infrakrasnuyu spektroskopiyu, a dlya opredeleniya sostava - ehlementarnyj analiz. Privedeny kharakte- ristiki nekotorykh produktov reaktsii, vklyuchayushchie ikh temperaturu plavleniya, plotnost', rastvorimost' i molekulyarnyj ves. Ustanovlena sopolimerizatsiya ehtilena s kazhdym iz sleduyushchikh monomerov: stirolom, metilmetakrilatom, venilatsetatom, akrilonitrilom, allilatsetatom, izobutilenom, khlorotriftoroehtilenom, trans-2-butenom, metilakrilatom, izoprenom, propilenom, khloristym vinilom, 1-butenom, tsis-2-butenom, okis'yu ugleroda, vinilpirrolidonom, metilvinilketonom i divinilbenzolom. Ustanovleno, chto dannye,-poluchennye ehksperimental'nym putem pri izuchenii, sistemy ehtilen-okis' ugleroda, udovletvoryayut linejnoj forme uravneniya sostava sopolimera. Ustanovleno, chto otnoshenie konstant udel'nykh skorostej dlya okisi ugleroda i ehtilena ({alpha}) sostavlyaet 22,0, chto oznachaet, chto okis' uglerode kak monomer aktivirovana v takop stepeni, chto ona prisoedinyaetsya k kontsu tsepochki svobodnykh radikalov ehtilena v 22 raza bystree chem ehtilenovyj monomer. (author)

  18. Results of a jet plume effects test on Rockwell International integrated space shuttle vehicle using a vehicle 5 configuration 0.02-scale model (88-OTS) in the 11 by 11 foot leg of the NASA/Ames Research Center unitary plan wind tunnel (IA19), volume 1

    Science.gov (United States)

    Nichols, M. E.

    1975-01-01

    Results are presented of jet plume effects test IA19 using a vehicle 5 configuration integrated space shuttle vehicle 0.02-scale model in the NASA/Ames Research Center 11 x 11-foot leg of the unitary plan wind tunnel. The jet plume power effects on the integrated vehicle static pressure distribution were determined along with elevon, main propulsion system nozzle, and solid rocket booster nozzle effectiveness and elevon hinge moments.

  19. Otázka stáří nejvyšší části líňského souvrství (mšensko-roudnická pánev, Český masiv) – nové indicie z vrtu Be-1 Bechlín

    Czech Academy of Sciences Publication Activity Database

    Zajíc, Jaroslav

    2012-01-01

    Roč. 2011, podzim (2012), s. 59-62 ISSN 0514-8057 R&D Projects: GA AV ČR IAA300130703 Institutional research plan: CEZ:AV0Z30130516 Keywords : Mšeno-Roudnice Basin * Carboniferous/ Permian boundary * Líně Formation * zoopalaeontology * biostratigraphy Subject RIV: DB - Geology ; Mineralogy http://www.geology.cz/zpravy/obsah/2011/zpravy_2011-13.pdf

  20. K otázkám některých základních lidských práv a svobod v souvislosti s právní ochranou biometrických údajů

    Czech Academy of Sciences Publication Activity Database

    Güttler, Vojen; Matejka, Ján

    2016-01-01

    Roč. 155, č. 12 (2016), s. 1033-1056 ISSN 0231-6625 R&D Projects: GA ČR(CZ) GA16-26910S Institutional support: RVO:68378122 Keywords : biometric data * sensitive personal data * private life Subject RIV: AG - Legal Sciences OBOR OECD: Law

  1. K otázce datování počátků kultury s keramikou pražského typu na Moravě. Příspěvek pro 15. mezinárodní sjezd slavistů v Minsku

    Czech Academy of Sciences Publication Activity Database

    Jelínková, Dagmar

    2012-01-01

    Roč. 53, č. 2 (2012), s. 7-21 ISSN 1211-7250 R&D Projects: GA ČR GA404/07/1629 Institutional support: RVO:68081758 Keywords : Prague-type-pottery culture * Southern Moravia * inhumation grave * sax * settlement * dating C14 Subject RIV: AC - Archeology, Anthropology, Ethnology http://dino.iabrno.cz/dokumenty/pv/PV53_2_studie/PV53_2_studie_1.pdf

  2. Thermodynamic properties of britholites CaxLay(SiO4)6-u(PO4)uOt, study of the properties of diffusion and fixation of lanthanide and trans-uranian ions in britholites: application in the field of luminescent materials and of storage of nuclear wastes

    International Nuclear Information System (INIS)

    El Ouenzerfi, R.

    2003-02-01

    This work deals in particular with the synthesis and the characterization of the apatitic oxy-silico-phosphates. In a first part is studied the quaternary system: CaO-La 2 O 3 -SiO 2 P 2 O 5 in order to determine the range in which the pure phospho-silicated apatites exist. Then, the obtained phases have been identified and characterized by chemical analysis methods, electron microprobe analysis, X-ray diffraction, infrared and Raman spectroscopies. The study of the uranium solubilization and diffusion in apatitic matrices has been carried out from the determination of the substitution limit, of the oxidation degree and of the diffusion coefficient of uranium in a phospho-silicated apatite. In a second part, the luminescence properties of the Eu 3+ and Ce 3+ ions in phospho-silicated apatites have been studied. This work allows to have a wider vision of the oxy-silico-phosphated apatites and of their synthesis conditions. The study of the physical and chemical properties of britholites doped with actinides or lanthanides ions will be useful to the study of the optical properties of these matrices. (O.M.)

  3. Možnosti využití jednoduché sebehodnoticí otázky pro měření úrovně pracovního stresu v průřezových dotazníkových šetřeních kvality pracovního života

    Czech Academy of Sciences Publication Activity Database

    Vinopal, Jiří

    2011-01-01

    Roč. 5, č. 2 (2011), s. 35-57 ISSN 1802-8152 Institutional research plan: CEZ:AV0Z70280505 Keywords : working stress measurement * quality of working life * SQWL Subject RIV: AO - Sociology, Demography

  4. Právní otázky související s problematikou translidí pod zorným úhlem rozhodnutí Velkého senátu ESLP ve věci Hämäläinen vs Finsko

    Czech Academy of Sciences Publication Activity Database

    Doležal, Adam

    2014-01-01

    Roč. 4, č. 3 (2014), s. 44-60 ISSN 1804-8137 R&D Projects: GA ČR(CZ) GA14-35646S Institutional support: RVO:68378122 Keywords : transgender * marriage * registered partnership Subject RIV: AG - Legal Sciences http://www.ilaw.cas.cz/medlawjournal/index.php/medlawjournal/article/view/82/80

  5. Identification and estimation ot carbohydrates using radioisotopic methods; Identification et dosage des hydrates de carbone a l'aide des radioisotopes; Identifikatsiya i opredelenie karbogidratov s pomoshch'yu radioizotopnykh metodov; Identificacion u valoracion de hidratos de carbono con ayuda de radioisotopos

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, G O; Criddle, W J [Department of Chemistry, University College, Cardiff (United Kingdom)

    1962-01-15

    Isotope-dilution methods have been developed to identify and estimate the small amount of products formed when carbohydrates are irradiated in aqueous solution with Co{sup 60} gamma-radiation. Conventional analytical methods proved inadequate. After irradiation of C{sup 14}-sugar solutions, the autoradiographs prepared after paper chromatography indicated extensive degradation. Using a reverse isotope-dilution procedure involving the addition of known carriers, and conversion of the fragments into crystalline derivatives, various constituents were quantitatively determined. It is possible to distinguish between d- and Z-isomers, and estimate each isomer independently. The method is applicable to other analytical problems in carbohydrate chemistry. A new method for scanning and recording the radioactivity along paper-chromatogram strips, which involves an inexpensive modification to conventional counting equipment, is described. (author) [French] On a mis au point des methodes de dilution isotopique destinees a identifier et a doser les menues quantites de produits qui se forment lorsque des hydrates de carbone en solution aqueuse sont irradies par les rayons gamma du cobalt-60. A cet egard, les methodes d'analyse classiques se sont revelees inadequates. Apres irradiation de solutions de sucre marque au carbone-14, les autoradiogrammes etablis a la suite d'une chromatographic sur papier indiquaient une forte degradation. En recourant a une methode de dilution isotopique inverse, avec adjonction d'entraineurs connus, et en operant une conversion des fragments en derives cristallins, on a pu determiner quantitativement plusieurs elements constitutifs. Il est possible de distinguer les isomeres dextrogyres des isomeres levogyres et de doser chaque isomere independamment. La methode peut etre appliquee a d'autres problemes d'analyse dans la chimie des hydrates de carbone. Le memoire decrit une nouvelle methode permettant d'explorer et d'enregistrer la radioactivite de chromatogrammes sur bandes de papier; elle n'exige qu'une modification peu couteuse du materiel de comptage traditionnel. (author) [Spanish] Dado que los metodos analiticos clasicos no permiten obtener resultados satisfactorios, los autores han perfeccionado unos metodos de dilucion isotopica para identificar y valorar los productos que se forman en pequenas cantidades al exponer hidratos de carbono en solucion acuosa a las radiaciones gamma del {sup 60}Co. Las autorradiografias de cromatogramas sobre papel, obtenidos despues de irradiar soluciones de azucares marcados con {sup 14}C, revelan una considerable degradacion molecular. Gracias a un metodo de dilucion isotopica inverso basado en la adicion de portadores conocidos, y en la obtencion de derivados cristalizados de los fragmentos, los autores han podido determinar cuantitativamente los siguientes constituyentes. El metodo descrito por los autores permite distinguir entre estereoisomeros y valorar cada lino de ellos por separado. Asimismo puede utilizarse para resolver otros problemas de orden analitico que plantea la quimica de los hidratos de carbono. Los autores describen un nuevo metodo de exploracion y registro de la radiactividad a lo largo de las tiras de papel en las que se ha desarrollado el cromatograma. Este metodo solo requiere una modificacion poco onerosa del equipo de recuento corriente. (author) [Russian] Dlya identifikatsii i otsenki nebol'shikh kolichestv obrazovavshikhsya produktov pri obluchenii karbogidratov v vodnom rastvore gamma-aktivnym kobal'tom-60 byli razrabotany metody razbavleniya izotopov. Obychnye zhe analiticheskie metody okazalis' nedostatochnymi. Po obluchenii rastvorov S14-sakhar podgotovlennye avtoradiografii posle khromatografii na bumage ukazyvayut na znachitel'noe snizhenie. Ispol'zovanie protsedury obratnogo izotopnogo rastvora, svyazannoj s dobavkoj izvestnykh nositelej i preobrazovaniem oskolkov v derivaty kristallov, byli opredeleny kolichestvennye razmery sleduyushchikh sostavnykh chastej : Mozhno razlichit' d- i i-izomery i proizvesti individual'nuyu otsenku kazhdogo iz nikh. EHtot metod primenyaetsya pri reshenii drugikh analiticheskikh problem v khimii karbogidratov. V doklade daetsya opisanie novogo metoda graficheskogo izobrazheniya i zapisi radio- aktivnosti po liniyam khromogrammy na bumage, chto vozmozhno osushchestvit' pri neznachitel'nykh zatratakh na modifikatsiyu obychnogo schetnogo oborudovaniya. (author)

  6. Urban Everyday Life in the Mirror of Unofficial Oikonymy. Review of the book: Akhmetova, M. V. (2015. Ot A-Ata do Iarska: slovar’ neofitsial’nykh nazvanii naselennykh punktov [From A-At to Yarsk: A Dictionary of Unofficial Settlement Names]. Moscow: FORUM

    Directory of Open Access Journals (Sweden)

    Marina V. Golomidova

    2016-11-01

    Full Text Available The paper provides a review of the content and structure of the dictionary of Russian unofficial oikonymy published by Maria Akhmetova. The reviewer points out the author’s ability to make a high-quality presentation of a large number of lexical units: more than 2 200 names and non-standard abbreviations for more than 800 settlements of Russia and neighbouring countries. The material was retrieved from a wide array of sources which include both traditional written texts (toponymic and regional dictionaries, dictionaries of slang, scholarly, journalistic and literary texts and relatively new practices of contemporary Internet communications (blogs, Internet forums, social networks, etc. The reviewer emphasizes the correct and adequate manner of lexicographic processing of unofficial settlement names, as well as the author’s theoretical reasoning on their functional specificity. A particular attention is paid to the ideas articulated in the introduction to the dictionary in which the author attempts to define the status of unofficial oikonyms within the toponymic system of a language, qualifying such names as a particular case of toponymic variability, the latter being the basis of a systemicfunctional approach to the interpretation of unofficial names. The reviewer concludes that Maria Akhmetova’s dictionary enlarges our view of sociolinguistic parameters of the functioning of unofficial oikonyms, which is reflected in an extremely detailed system of labels referring to hitchhikers’ slang, military and naval jargon, obsolete vocabulary, journalistic discourse, nonce words, and others. The dictionary contains rich data that can be used in lexicological, morphological, onomastic, sociolinguistic, anthropological research, but also in studies of urban folklore and urban everyday life.

  7. Obecně závazné vyhlášky obcí v nové judikatuře Ústavního soudu: pohyb zvířat v obci a související otázky

    Czech Academy of Sciences Publication Activity Database

    Müllerová, Hana

    2011-01-01

    Roč. 44, č. 7 (2011), s. 385-403 ISSN 0139-6005 R&D Projects: GA ČR GA407/08/1053 Institutional research plan: CEZ:AV0Z70680506 Keywords : animal regulation * municipal legislation * Animal Welfare Act Subject RIV: AG - Legal Sciences

  8. Aktuální vývoj v otázce definice zločinu agrese ve smyslu čl. 5 Ŕímského statutu Mezinárodní trestního soudu

    Czech Academy of Sciences Publication Activity Database

    Popenková, Monika

    2008-01-01

    Roč. 147, č. 5 (2008), s. 555-585 ISSN 0231-6625 R&D Projects: GA AV ČR KJB700680601 Institutional research plan: CEZ:AV0Z70680506 Keywords : crime of aggression * International Criminal Court * international law Subject RIV: AG - Legal Sciences

  9. Matematické modely chování ocelové obloukové výztuže chodeb při dynamickém zatížení následkem důlních otřesů

    Czech Academy of Sciences Publication Activity Database

    Šňupárek, Richard; Zeman, Vladislav; Horyl, P.; Schellong, L.

    2007-01-01

    Roč. 55, č. 1 (2007), s. 16-20 ISSN 1210-7697 R&D Projects: GA ČBÚ AACBU34-03 Institutional research plan: CEZ:AV0Z30860518 Keywords : rock bursts * dynamic loading * behavior of arched steel support s Subject RIV: DH - Mining , incl. Coal Mining

  10. Oxytocin and Estrogen Receptor β in the Brain: An Overview.

    Science.gov (United States)

    Acevedo-Rodriguez, Alexandra; Mani, Shaila K; Handa, Robert J

    2015-01-01

    Oxytocin (OT) is a neuropeptide synthesized primarily by neurons of the paraventricular and supraoptic nuclei of the hypothalamus. These neurons have axons that project into the posterior pituitary and release OT into the bloodstream to promote labor and lactation; however, OT neurons also project to other brain areas where it plays a role in numerous brain functions. OT binds to the widely expressed OT receptor (OTR), and, in doing so, it regulates homeostatic processes, social recognition, and fear conditioning. In addition to these functions, OT decreases neuroendocrine stress signaling and anxiety-related and depression-like behaviors. Steroid hormones differentially modulate stress responses and alter OTR expression. In particular, estrogen receptor β activation has been found to both reduce anxiety-related behaviors and increase OT peptide transcription, suggesting a role for OT in this estrogen receptor β-mediated anxiolytic effect. Further research is needed to identify modulators of OT signaling and the pathways utilized and to elucidate molecular mechanisms controlling OT expression to allow better therapeutic manipulations of this system in patient populations.

  11. Organotin Exposure and Vertebrate Reproduction: A Review

    Directory of Open Access Journals (Sweden)

    Julia Fernandez Puñal de Araújo

    2018-03-01

    Full Text Available Organotin (OTs compounds are organometallic compounds that are widely used in industry, such as in the manufacture of plastics, pesticides, paints, and others. OTs are released into the environment by anthropogenic actions, leading to contact with aquatic and terrestrial organisms that occur in animal feeding. Although OTs are degraded environmentally, reports have shown the effects of this contamination over the years because it can affect organisms of different trophic levels. OTs act as endocrine-disrupting chemicals (EDCs, which can lead to several abnormalities in organisms. In male animals, OTs decrease the weights of the testis and epididymis and reduce the spermatid count, among other dysfunctions. In female animals, OTs alter the weights of the ovaries and uteri and induce damage to the ovaries. In addition, OTs prevent fetal implantation and reduce mammalian pregnancy rates. OTs cross the placental barrier and accumulate in the placental and fetal tissues. Exposure to OTs in utero leads to the accumulation of lipid droplets in the Sertoli cells and gonocytes of male offspring in addition to inducing early puberty in females. In both genders, this damage is associated with the imbalance of sex hormones and the modulation of the hypothalamic–pituitary–gonadal axis. Here, we report that OTs act as reproductive disruptors in vertebrate studies; among the compounds are tetrabutyltin, tributyltin chloride, tributyltin acetate, triphenyltin chloride, triphenyltin hydroxide, dibutyltin chloride, dibutyltin dichloride, diphenyltin dichloride, monobutyltin, and azocyclotin.

  12. Human ovolution and plasma oxytocin

    International Nuclear Information System (INIS)

    Kumaresan, Perianna; Kumaresan, Malathi; Hossini, Mahmood; Arellano, Carolina; Vasicka, Alois

    1983-01-01

    Plasma oxytocin (OT) concentrations were measured by radioimmunoassay (RIA) method without extracting plasma in 11 normal menstruating women. Mean plasma OT level began to increase steadily from the 7th day of the menstrual cycle and this level rose up to 20+-5 μU/ml (Mean+-S.E.) on the 10th day of the cycle. OT level declined to 13+-6 μU/ml on the day of the LH peak and continuously declined for another 2 days - then rose. The OT level was higher during the follicular phase than during the luteal phase. In 1 individual OT measured in 2 cycles a year apart showed the highest level of OT coincided with LH and FSH peak and abruptly declined. When there was the highest level of progesterone, the OT level was measurable 1 out of 11 cycles. From this study, we conclude that OT may have a role in human ovulation either synergistically or alone with other ovulatory mechanisms and ovarian estradiol and progesterone control the secretion of OT and also suggests that OT may play some role in the regulation of the luteolysis and the menstrual cycle in women. (author)

  13. Orthodontic treatment for disabled children: a survey of parents' attitudes and overall satisfaction.

    Science.gov (United States)

    Abeleira, María Teresa; Pazos, Elisabeth; Ramos, Isabel; Outumuro, Mercedes; Limeres, Jacobo; Seoane-Romero, Juan; Diniz, Marcio; Diz, Pedro

    2014-08-05

    Many patients with disability require orthodontic treatment (OT) to achieve adequate oral function and aesthetic appearance. The cooperation of disabled patients and of their parents is central to the success of OT, as treatment can involve ethical dilemmas. The aim of this study was to analyze the motivation, expectations and overall satisfaction with OT among parents of patients with disabilities. The parents of 60 disabled Spanish children with physical, mental and/or sensory impairment undergoing OT were surveyed on attitudes to OT and level of satisfaction with the outcomes. The survey consisted of 23 questions in 4 sections: attitude and adaptation, benefits, adverse effects, and level of satisfaction after completion of OT. A control group formed of the parents of 60 healthy children undergoing OT at the same institution were also surveyed. Parents of disabled children undergoing OT showed a high level of motivation and they are willing to collaborate in oral hygiene procedures. Adaptation to the removable appliances was poorer in disabled children but adaptation to fixed appliances was excellent. OT can provide a marked improvement in quality of life, social relationships and oral functionality in disabled children. Among parents of disabled children undergoing OT, the perceived level of overall satisfaction was very high and expectations were often exceeded.

  14. Conditioned same-sex partner preference in male rats is facilitated by oxytocin and dopamine: effect on sexually dimorphic brain nuclei.

    Science.gov (United States)

    Triana-Del Rio, Rodrigo; Tecamachaltzi-Silvarán, Miriam B; Díaz-Estrada, Victor X; Herrera-Covarrubias, Deissy; Corona-Morales, Aleph A; Pfaus, James G; Coria-Avila, Genaro A

    2015-04-15

    Conditioned same-sex partner preference can develop in male rats that undergo cohabitation under the effects of quinpirole (QNP, D2 agonist). Herein, we assessed the development of conditioned same-sex social/sexual preference in males that received either nothing, saline, QNP, oxytocin (OT), or QNP+OT during cohabitation with another male (+) or single-caged (-). This resulted in the following groups: (1) Intact-, (2) Saline+, (3) QNP-, (4) OT-, (5) QNP+, (6) OT+ and (7) QNP/OT+. Cohabitation occurred during 24h in a clean cage with a male partner that bore almond scent on the back as conditioned stimulus. This was repeated every 4 days for a total of three trials. Social and sexual preference were assessed four days after the last conditioning trial in a drug-free test in which experimental males chose between the scented familiar male and a novel sexually receptive female. Results showed that males from groups Intact-, Saline+, QNP- and OT- displayed a clear preference for the female (opposite-sex), whereas groups QNP+, OT+ and QNP/OT+ displayed socio/sexual preference for the male partner (same-sex). In Experiment 2, the brains were processed for Nissl dye and the area size of two sexually dimorphic nuclei (SDN-POA and SON) was compared between groups. Males from groups OT-, OT+ and QNP/OT+ expressed a smaller SDN-POA and groups QNP+ and QNP/OT+ expressed a larger SON. Accordingly, conditioned same-sex social/sexual partner preference can develop during cohabitation under enhanced D2 or OT activity but such preference does not depend on the area size of those sexually dimorphic nuclei. Copyright © 2015 Elsevier B.V. All rights reserved.

  15. Comprehensive, blinded assessment of balance in orthostatic tremor.

    Science.gov (United States)

    Bhatti, Danish; Thompson, Rebecca; Xia, Yiwen; Hellman, Amy; Schmaderer, Lorene; Suing, Katie; McKune, Jennifer; Penke, Cynthia; Iske, Regan; Roeder, Bobbi Jo; Siu, Ka-Chun; Bertoni, John M; Torres-Russotto, Diego

    2018-02-01

    Orthostatic Tremor (OT) is a movement disorder characterized by a sensation of unsteadiness and tremors in the 13-18 Hz range present upon standing. The pathophysiology of OT is not well understood but there is a relationship between the sensation of instability and leg tremors. Despite the sensation of unsteadiness, OT patients do not fall often and balance in OT has not been formally assessed. We present a prospective blinded study comparing balance assessment in patients with OT versus healthy controls. We prospectively enrolled 34 surface Electromyography (EMG)-confirmed primary OT subjects and 21 healthy controls. Participants underwent evaluations of balance by blinded physical therapists (PT) with standardized, validated, commonly used balance scales and tasks. OT subjects were mostly female (30/34, 88%) and controls were majority males (13/20, 65%). The average age of OT subjects was 68.5 years (range 54-87) and for controls was 69.4 (range 32-86). The average duration of OT symptoms was 18 years. OT subjects did significantly worse on all the balance scales and on most balance tasks including Berg Balance Scale, Functional Gait Assessment, Dynamic Gait Index, Unipedal Stance Test, Functional Reach Test and pull test. Gait speed and five times sit to stand were normal in OT. Common validated balance scales are significantly abnormal in primary OT. Despite the objective finding of impaired balance, OT patients do not commonly have falls. The reported sensation of unsteadiness in this patient population seems to be out of proportion to the number of actual falls. Further studies are needed to determine which components of commonly used balance scales are affected by a sensation of unsteadiness and fear of falling. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. The organizational effects of oxytocin on the central expression of estrogen receptor α and oxytocin in adulthood

    Directory of Open Access Journals (Sweden)

    Papademetriou Eros

    2007-09-01

    Full Text Available Abstract Background Previous studies have demonstrated that neonatal manipulation of oxytocin (OT has effects on the expression of estrogen receptor α (ERα and the central production of oxytocin observed in juveniles (at weaning, 21 days of age. The goal of this study was to determine whether the effects of neonatal manipulation of OT last into adulthood, and if the effects differ from those observed during the early postnatal period. On the first day of life, prairie voles (Microtus ochrogaster received one of three doses of OT (High, 3 μg; Med, 0.3 μg; Low, 0.03 μg, an OT antagonist, or isotonic saline. Another group was handled, but not injected. Then as adults, brains were collected, sectioned, and stained for ERα or OT using immunocytochemistry. Results In females, treatment with OT increased the expression of ERα immunoreactivity in the ventral lateral septum (0.03 μg and the ventromedial nucleus of the hypothalamus and central amygdala (0.3 μg. In males, OT antagonist increased ERα expression in the bed nucleus of the stria terminalis. There was no apparent effect of OT on the number of cells producing OT in the paraventricular nucleus of the hypothalamus. Conclusion The current results suggest that neonatal manipulation of OT has long-term organizational effects on the expression of ERα in both males and females. The lack of effect on OT neurons in the paraventricular nucleus suggests that some developmental effects of OT previously observed in weanlings do not persist into adulthood. Developmental effects of OT on ERα patterns were sexually dimorphic, dose-dependent, and site-specific.

  17. AFM investigation of effect of absorbed water layer structure on growth mechanism of octadecyltrichlorosilane self-assembled monolayer on oxidized silicon

    International Nuclear Information System (INIS)

    Li, Shaowei; Zheng, Yanjun; Chen, Changfeng

    2016-01-01

    The growth mechanism of an octadecyltrichlorosilane (OTS) self-assembled monolayer on a silicon oxide surface at various relative humidities has been investigated. Atomic force microscopy images show that excess water may actually hinder the nucleation and growth of OTS islands. A moderate amount of water is favorable for the nucleation and growth of OTS islands in the initial stage; however, the completion of the monolayer is very slow in the final stage. The growth of OTS islands on a low-water-content surface maintains a relatively constant speed and requires the least amount of time. The mobility of water molecules is thought to play an important role in the OTS monolayers, and a low-mobility water layer provides a steady condition for OTS monolayer growth.

  18. Emotional suppression explains the link between early life stress and plasma oxytocin.

    Science.gov (United States)

    Mohiyeddini, Changiz; Opacka-Juffry, Jolanta; Gross, James J

    2014-01-01

    Early life stress (ELS) has been found to be associated with lower concentrations of plasma oxytocin (OT) in adulthood. It is not yet clear, however, what mechanisms underlie this association. The goal of the present study was to test the role of emotional suppression as an intervening variable between ELS in childhood and plasma OT. In a nonclinical sample of 90 men, ELS, emotional suppression, and plasma OT were assessed. Emotional suppression was positively associated with ELS (r = 0.37, p emotion regulation strategy - was not correlated with ELS or plasma OT concentrations. Cross-sectional regression analyses revealed that the ELS explained variance in plasma OT via emotional suppression. Moderation analyses revealed that the combination of high ELS and high emotional suppression was associated with the lowest concentrations of plasma oxytocin. These findings are consistent with the view that emotional suppression may be one pathway linking ELS and OT.

  19. Sex, Receptors and Attachment: A Review of Individual Factors Influencing Response to Oxytocin

    Directory of Open Access Journals (Sweden)

    Kai S Macdonald

    2013-01-01

    Full Text Available As discussed in the larger review in this special issue (MacDonald and Feifel, intranasal oxytocin (IN OT is demonstrating a growing potential as a therapeutic agent in psychiatry. Importantly, research suggests that a variety of individual factors may influence a person’s response to OT. In this mini-review, I provides a review of three: (1 sex and hormonal status; (2 genetic variation in aspects of the OT system (i.e. OT receptors; and (3 attachment history. Each of these factors will be important to monitor as we strive to develop a richer understanding of OT's role in human development, brain-based disease, and the potential for individualized, OT-targeted treatments.

  20. Radioimmunoassay of urine oxytocin in man

    International Nuclear Information System (INIS)

    Zebidi, A.; Geelen, G.; Allevard, A.M.; Sempore, B.; Jarsaillon, E.; Meunier, C.; Gharib, C.

    1978-01-01

    A radioimmunoassay (RIA) for oxytocin (OT) in urine is described. 125 I-OT was prepared, and antibodies were raised in rabbits against OT coupled to bovine serumalbumine. This allowed us to set up a RIA for OT which limit of detection is 1.25 pg/tube (0.6 μU). The use of an extraction procedure using CG 50 Amberlite is essential. The recovery after extraction reaches 70.5 %. pH 5 is the optimum pH were urine samples must be stored. The superposition of the elution peak of endogenous OT on that of exogenous hormone is an argument in favour of the validity of such an extraction procedure. Daily urinary excretion of OT reaches 9.58 mU +- 3.48 in 18 healthy young men [fr

  1. An Early Postnatal Oxytocin Treatment Prevents Social and Learning Deficits in Adult Mice Deficient for Magel2, a Gene Involved in Prader-Willi Syndrome and Autism.

    Science.gov (United States)

    Meziane, Hamid; Schaller, Fabienne; Bauer, Sylvian; Villard, Claude; Matarazzo, Valery; Riet, Fabrice; Guillon, Gilles; Lafitte, Daniel; Desarmenien, Michel G; Tauber, Maithé; Muscatelli, Françoise

    2015-07-15

    Mutations of MAGEL2 have been reported in patients presenting with autism, and loss of MAGEL2 is also associated with Prader-Willi syndrome, a neurodevelopmental genetic disorder. This study aimed to determine the behavioral phenotype of Magel2-deficient adult mice, to characterize the central oxytocin (OT) system of these mutant mice, and to test the curative effect of a peripheral OT treatment just after birth. We assessed the social and cognitive behavior of Magel2-deficient mice, analyzed the OT system of mutant mice treated or not by a postnatal administration of OT, and determined the effect of this treatment on the brain. Magel2 inactivation induces a deficit in social recognition and social interaction and a reduced learning ability in adult male mice. In these mice, we reveal anatomical and functional modifications of the OT system and show that these defects change from birth to adulthood. Daily administration of OT in the first postnatal week was sufficient to prevent deficits in social behavior and learning abilities in adult mutant male mice. We show that this OT treatment partly restores a normal OT system. Thus, we report that an alteration of the OT system around birth has long-term consequences on behavior and on cognition. Importantly, an acute OT treatment of Magel2-deficient pups has a curative effect. Our study reveals that OT plays a crucial role in setting social behaviors during a period just after birth. An early OT treatment in this critical period could be a novel therapeutic approach for the treatment of neurodevelopmental disorders such as Prader-Willi syndrome and autism. Copyright © 2015 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  2. A New Approach to Practical Active-Secure Two-Party Computation

    DEFF Research Database (Denmark)

    Nielsen, Jesper Buus; Nordholt, Peter Sebastian; Orlandi, Claudio

    2012-01-01

    We propose a new approach to practical two-party computation secure against an active adversary. All prior practical protocols were based on Yao’s garbled circuits. We use an OT-based approach and get efficiency via OT extension in the random oracle model. To get a practical protocol we introduce...... a number of novel techniques for relating the outputs and inputs of OTs in a larger construction....

  3. Manipulation of the oxytocin system alters social behavior and attraction in pair-bonding primates, Callithrix penicillata.

    Science.gov (United States)

    Smith, Adam S; Agmo, Anders; Birnie, Andrew K; French, Jeffrey A

    2010-02-01

    The establishment and maintenance of stable, long-term male-female relationships, or pair-bonds, are marked by high levels of mutual attraction, selective preference for the partner, and high rates of sociosexual behavior. Central oxytocin (OT) affects social preference and partner-directed social behavior in rodents, but the role of this neuropeptide has yet to be studied in heterosexual primate relationships. The present study evaluated whether the OT system plays a role in the dynamics of social behavior and partner preference during the first 3 weeks of cohabitation in male and female marmosets, Callithrix penicillata. OT activity was stimulated by intranasal administration of OT, and inhibited by oral administration of a non-peptide OT-receptor antagonist (L-368,899; Merck). Social behavior throughout the pairing varied as a function of OT treatment. Compared to controls, marmosets initiated huddling with their social partner more often after OT treatments but reduced proximity and huddling after OT antagonist treatments. OT antagonist treatment also eliminated food sharing between partners. During the 24-h preference test, all marmosets interacted more with an opposite-sex stranger than with the partner. By the third-week preference test, marmosets interacted with the partner and stranger equally with the exception that intranasal-OT treatments facilitated initial partner-seeking behavior over initial contact with the stranger. Our findings demonstrate that pharmacological manipulations of OT activity alter partner-directed social behavior during pair interactions, suggesting that central OT may facilitate the process of pair-bond formation and social relationships in marmoset monkeys. Published by Elsevier Inc.

  4. Can the Short-Term Toxicity of Water-Soluble Jet Fuel Hydrocarbons Produce Long-Lasting Effects in Lake Plankton Communities?

    Science.gov (United States)

    1983-09-01

    Hutchinson. 1975. The effects of water soluble petroleum components on the growth ot Chlorella vulgaris Beijerinck. Environ. Pollut. 9:157-1/4. Karydis, M. and...Richard Starr Algal collection or Ankistrodesmus sp. or Chlorella sp. from the Carolina Biological collection. The cultures were unialgal but not... Chlorella were grown in BBM medium. After five days ot growth, half ot the flasks (3) for each species were spiked with 0.1 ml of toluene. The , .. flasks

  5. Plasma oxytocin concentrations are lower in depressed vs. healthy control women and are independent of cortisol.

    Science.gov (United States)

    Yuen, Kaeli W; Garner, Joseph P; Carson, Dean S; Keller, Jennifer; Lembke, Anna; Hyde, Shellie A; Kenna, Heather A; Tennakoon, Lakshika; Schatzberg, Alan F; Parker, Karen J

    2014-04-01

    The neuropeptide oxytocin (OT) promotes social behavior and attenuates stress responsivity in mammals. Recent clinical evidence suggests OT concentrations may be dysregulated in major depression. This study extends previous research by testing whether: 1) OT concentrations vary systematically in depressive disorders with and without hypercortisolemia, 2) gender differences in OT concentrations are observed in depressed vs. healthy control participants, and 3) OT concentrations are predictive of clinical phenotypes. Plasma OT concentrations of psychotic major depressive (PMD; n = 14: 10 female, 4 male), non-psychotic major depressive (NPMD; n = 17: 12 female, 5 male), and non-depressed, healthy control (n = 19: 11 female, 8 male) participants were assayed at 2000, 2400, 0400, and 0800 h. Plasma cortisol concentrations were quantified at 2300 h, and clinical phenotypes were determined. As expected, PMD participants, compared to NPMD and healthy control participants, showed higher plasma cortisol concentrations. Although both depressed groups showed similar OT concentrations, a significant interaction effect between group and gender was observed. Specifically, depressed females exhibited lower mean OT concentrations than depressed males. Further, depressed vs. healthy control female participants exhibited lower mean OT concentrations, whereas depressed vs. healthy control male participants showed a trend in the opposite direction. OT concentrations were also predictive of desirability, drug dependence, and compulsivity scores as measured by the Million Clinical Multiaxial Inventory-III. All findings were independent of cortisol. These data suggest that OT signaling may provide a mechanism by which to better understand female-biased risk to develop depressive disorders and that plasma OT concentrations may be a useful biomarker of certain clinical phenotypes. Copyright © 2013. Published by Elsevier Ltd.

  6. Oxytocin mechanisms of stress response and aggression in a territorial finch.

    Science.gov (United States)

    Goodson, James L; Schrock, Sara E; Kingsbury, Marcy A

    2015-03-15

    All jawed vertebrates produce a form of oxytocin (OT), and in birds, mammals and fish, OT is strongly associated with affiliation. However, remarkably few data are available on the roles of OT and OT receptors (OTRs) in aggression. Because OT and OTRs exert anxiolytic effects in mammals (although context-specific) and modulate stress coping, we hypothesized that OTR activation is at least permissive for territorial aggression. Indeed, we find that peripheral injections of an OTR antagonist significantly reduce male-male and female-female aggression in a highly territorial finch. This finding suggests the hypothesis that aggression is accompanied by an increase in transcriptional (Fos) activity of OT neurons, but contrary to this hypothesis, we find that dominant male residents do not elevate OT-Fos colocalization following an aggressive encounter and that OT-Fos colocalization in the preoptic area and hypothalamus correlates negatively with aggression. Furthermore, OT-Fos colocalization increases dramatically in males that were aggressively subjugated or pursued by a human hand, likely reflecting OT modulation of stress response. Because OT inhibits the hypothalamo-pituitary-adrenal axis, the antagonist effects may reflect the fact that aggressive birds and mammals tend to be hyporesponsive to stress. If this is correct, then 1) the observed effects of OTR antagonism may reflect alterations in corticosterone feedback to the brain rather than centrally mediated OTR effects, and 2) the negative correlation between OT-Fos colocalization and aggression may reflect the fact that more aggressive, stress hyporesponsive males require less inhibition of the hypothalamo-pituitary-adrenal axis than do less aggressive males, despite the requirement of that inhibition for the normal display of aggression. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Low dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized 4-way crossover trial with nasal cavity dimension assessment

    OpenAIRE

    Quintana, Daniel; Westlye, Lars Tjelta; Rustan, Øyvind; Tesli, Natalia; Poppy, Claire; Smevik, Hanne; Tesli, Martin Steen; Røine, Marianne; Mahmoud, Ramy; Smerud, Knut Terje; Djupesland, Per G.; Andreassen, Ole Andreas

    2015-01-01

    Despite the promise of intranasal oxytocin (OT) for modulating social behavior, recent work has provided mixed results. This may relate to suboptimal drug deposition achieved with conventional nasal sprays, inter-individual differences in nasal physiology and a poor understanding of how intranasal OT is delivered to the brain in humans. Delivering OT using a novel ?Breath Powered' nasal device previously shown to enhance deposition in intranasal sites targeted for nose-to-brain transport, we ...

  8. Low-dose oxytocin delivered intranasally with Breath Powered device affects social-cognitive behavior: a randomized four-way crossover trial with nasal cavity dimension assessment.

    Science.gov (United States)

    Quintana, D S; Westlye, L T; Rustan, Ø G; Tesli, N; Poppy, C L; Smevik, H; Tesli, M; Røine, M; Mahmoud, R A; Smerud, K T; Djupesland, P G; Andreassen, O A

    2015-07-14

    Despite the promise of intranasal oxytocin (OT) for modulating social behavior, recent work has provided mixed results. This may relate to suboptimal drug deposition achieved with conventional nasal sprays, inter-individual differences in nasal physiology and a poor understanding of how intranasal OT is delivered to the brain in humans. Delivering OT using a novel 'Breath Powered' nasal device previously shown to enhance deposition in intranasal sites targeted for nose-to-brain transport, we evaluated dose-dependent effects on social cognition, compared response with intravenous (IV) administration of OT, and assessed nasal cavity dimensions using acoustic rhinometry. We adopted a randomized, double-blind, double-dummy, crossover design, with 16 healthy male adults completing four single-dose treatments (intranasal 8 IU (international units) or 24 IU OT, 1 IU OT IV and placebo). The primary outcome was social cognition measured by emotional ratings of facial images. Secondary outcomes included the pharmacokinetics of OT, vasopressin and cortisol in blood and the association between nasal cavity dimensions and emotional ratings. Despite the fact that all the treatments produced similar plasma OT increases compared with placebo, there was a main effect of treatment on anger ratings of emotionally ambiguous faces. Pairwise comparisons revealed decreased ratings after 8 IU OT in comparison to both placebo and 24 IU OT. In addition, there was an inverse relationship between nasal valve dimensions and anger ratings of ambiguous faces after 8-IU OT treatment. These findings provide support for a direct nose-to-brain effect, independent of blood absorption, of low-dose OT delivered from a Breath Powered device.

  9. Uterine and placental expression of canine oxytocin receptor during pregnancy and normal and induced parturition.

    OpenAIRE

    Gram A Boos A Kowalewski MP.

    2014-01-01

    Abstract Oxytocin (OT) plays an important role as an inducer of uterine contractility acting together with its receptor (OTR) to increase synthesis of prostaglandins. Although OT is commonly used in the treatment for dystocia and uterine inertia in the bitch little attention has been paid to the role of OT in mechanisms regulating parturition in the dog so that knowledge about the expression of OTR in the canine uterus and placenta is sparse. Consequently the expression and cellular localizat...

  10. Influence of oxytocin on emotion recognition from body language: A randomized placebo-controlled trial.

    Science.gov (United States)

    Bernaerts, Sylvie; Berra, Emmely; Wenderoth, Nicole; Alaerts, Kaat

    2016-10-01

    The neuropeptide 'oxytocin' (OT) is known to play a pivotal role in a variety of complex social behaviors by promoting a prosocial attitude and interpersonal bonding. One mechanism by which OT is hypothesized to promote prosocial behavior is by enhancing the processing of socially relevant information from the environment. With the present study, we explored to what extent OT can alter the 'reading' of emotional body language as presented by impoverished biological motion point light displays (PLDs). To do so, a double-blind between-subjects randomized placebo-controlled trial was conducted, assessing performance on a bodily emotion recognition task in healthy adult males before and after a single-dose of intranasal OT (24 IU). Overall, a single-dose of OT administration had a significant effect of medium size on emotion recognition from body language. OT-induced improvements in emotion recognition were not differentially modulated by the emotional valence of the presented stimuli (positive versus negative) and also, the overall tendency to label an observed emotional state as 'happy' (positive) or 'angry' (negative) was not modified by the administration of OT. Albeit moderate, the present findings of OT-induced improvements in bodily emotion recognition from whole-body PLD provide further support for a link between OT and the processing of socio-communicative cues originating from the body of others. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Involvement of the oxytocin system in the bed nucleus of the stria terminalis in the sex-specific regulation of social recognition

    Science.gov (United States)

    Dumais, Kelly M.; Alonso, Andrea G.; Immormino, Marisa A.; Bredewold, Remco; Veenema, Alexa H.

    2015-01-01

    Sex differences in the oxytocin (OT) system in the brain may explain why OT often regulates social behaviors in sex-specific ways. However, a link between sex differences in the OT system and sex-specific regulation of social behavior has not been tested. Here, we determined whether sex differences in the OT receptor (OTR) or in OT release in the posterior bed nucleus of the stria terminalis (pBNST) mediates sex-specific regulation of social recognition in rats. We recently showed that, compared to female rats, male rats have a three-fold higher OTR binding density in the pBNST, a sexually dimorphic area implicated in the regulation of social behaviors. We now demonstrate that OTR antagonist (5 ng/0.5 μl/side) administration into the pBNST impairs social recognition in both sexes, while OT (100 pg/0.5 μl/side) administration into the pBNST prolongs the duration of social recognition in males only. These effects seem specific to social recognition, as neither treatment altered total social investigation time in either sex. Moreover, baseline OT release in the pBNST, as measured with in vivo microdialysis, did not differ between the sexes. However, males showed higher OT release in the pBNST during social recognition compared to females. These findings suggest a sex-specific role of the OT system in the pBNST in the regulation of social recognition. PMID:26630388

  12. Oxytocin and prolactin release after hypertonic saline administration in melatonin-treated male Syrian hamsters

    Energy Technology Data Exchange (ETDEWEB)

    Juszczak, M.; Steger, R.W.; Fadden, C.; Bartke, A. [Southern Illinois Univ., Carbondale, IL (United States)

    1996-12-31

    The aim of the present investigations was to examine the effects of melatonin (Mel) on oxytocin (OT) release under conditions of osmotic stimulation, brought about by hypertonic saline administration, as well as to determine whether osmotically stimulated OT release in Mel-treated Syrian hamster is associated with alterations in the release of prolactin (PRL) and in norepinephrine (NE) and dopamine (DA) content in the hypothalamus. In both Mel- and vehicle-treated hamsters, injection of hypertonic saline was followed by a significant decrease in OT content in the pituitary neurointermediate lobe (NIL) and elevation of plasma OT and PRL levels. Melatonin injections had no significant affect on NIL OT content in either isotonic- or hypertonic-saline treated animals. Pretreatment with Mel did not alter plasma OT or PRL levels in isotonic saline-injected animals. However, Mel facilitated the release of OT, but prevented the release of PRL after hypertonic saline administration. Melatonin treatment reduced hypothalamic NE content (but not that of DA) in isotonic-saline treated animals. After osmotic stimulation, hypothalamic content of NE and DA was significantly lower in Mel-treated than in vehicle-treated animals. Data from the present study suggest that the osmotically-stimulated release of OT and PRL seems to be related to the activation of noradrenergic rather than dopaminergic transmission. Both dopaminergic and noradrenergic transmission may be, however, involved in mediating the effects of Mel on the osmotically-activated OT and PRL release. (author). 48 refs, 3 figs.

  13. Olfactory tubercle stimulation alters odor preference behavior and recruits forebrain reward and motivational centers

    Directory of Open Access Journals (Sweden)

    Brynn J FitzGerald

    2014-03-01

    Full Text Available Rodents show robust behavioral responses to odors, including strong preferences or aversions for certain odors. The neural mechanisms underlying the effects of odors on these behaviors in animals are not well understood. Here, we provide an initial proof-of-concept study into the role of the olfactory tubercle (OT, a structure with known anatomical connectivity with both brain reward and olfactory structures, in regulating odor-motivated behaviors. We implanted c57bl/6 male mice with an ipsilateral bipolar electrode into the OT to administer electric current and thereby yield gross activation of the OT. We confirmed that electrical stimulation of the OT was rewarding, with mice frequently self-administering stimulation on a fixed ratio schedule. In a separate experiment, mice were presented with either fox urine or peanut odors in a three-chamber preference test. In absence of OT stimulation, significant preference for the peanut odor chamber was observed which was abolished in the presence of OT stimulation. Perhaps providing a foundation for this modulation in behavior, we found that OT stimulation significantly increased the number of c-Fos positive neurons in not only the OT, but also in forebrain structures essential to motivated behaviors, including the nucleus accumbens and lateral septum. The present results support the notion that the OT is integral to the display of motivated behavior and possesses the capacity to modulate odor hedonics either by directly altering odor processing or perhaps by indirect actions on brain reward and motivation structures.

  14. OSD’s Obligation & Expenditure Rate Goals: An Examination of the Factors Contributing to the Interference

    Science.gov (United States)

    2015-04-30

    Prepamg OAE leYd t-end dec$01𔃻 ~ 4 15 218 F 15 lack ot dec$01𔃻 ~at expected~ ~ 4 22 252 f 18 ot new OSO /SeMce poky 4~ 4 20 2 59 F17 directed POM 4...tacwed ~ 357 223 F35 Wehhold 35, 358 234 I F3S oa.IA edmnsVlltNe ktoons 35, 3 42 236 F37 RedorecbOt’t ot contr.cw efforts 35, 3 47 223 F38 OSO

  15. Statistical and Methodological Considerations for the Interpretation of Intranasal Oxytocin Studies.

    Science.gov (United States)

    Walum, Hasse; Waldman, Irwin D; Young, Larry J

    2016-02-01

    Over the last decade, oxytocin (OT) has received focus in numerous studies associating intranasal administration of this peptide with various aspects of human social behavior. These studies in humans are inspired by animal research, especially in rodents, showing that central manipulations of the OT system affect behavioral phenotypes related to social cognition, including parental behavior, social bonding, and individual recognition. Taken together, these studies in humans appear to provide compelling, but sometimes bewildering, evidence for the role of OT in influencing a vast array of complex social cognitive processes in humans. In this article, we investigate to what extent the human intranasal OT literature lends support to the hypothesis that intranasal OT consistently influences a wide spectrum of social behavior in humans. We do this by considering statistical features of studies within this field, including factors like statistical power, prestudy odds, and bias. Our conclusion is that intranasal OT studies are generally underpowered and that there is a high probability that most of the published intranasal OT findings do not represent true effects. Thus, the remarkable reports that intranasal OT influences a large number of human social behaviors should be viewed with healthy skepticism, and we make recommendations to improve the reliability of human OT studies in the future. Copyright © 2016 Society of Biological Psychiatry. Published by Elsevier Inc. All rights reserved.

  16. Melanocortin Receptor Agonists Facilitate Oxytocin-Dependent Partner Preference Formation in the Prairie Vole.

    Science.gov (United States)

    Modi, Meera E; Inoue, Kiyoshi; Barrett, Catherine E; Kittelberger, Kara A; Smith, Daniel G; Landgraf, Rainer; Young, Larry J

    2015-07-01

    The central melanocortin (MC) system has been widely studied for its effects on food intake and sexual behavior. However, the MC system, and more specifically the MC4 receptor (MC4R), also interacts with neurochemical systems that regulate socioemotional behaviors, including oxytocin (OT) and dopamine. In monogamous prairie voles, OT and dopamine interact to promote partner preference formation, a laboratory measure of an enduring social bond between mates. Here we investigated the effects of MC receptor activation on partner preference formation in prairie voles, as well as the interaction between the MC and OT systems during this process. Peripheral administration of the brain penetrant MC3/4R receptor peptide agonist, Melanotan II (MTII), and the highly selective, small-molecule MC4R agonist, Pf-446687, enhanced partner preference formation in the prairie vole, but not in the non-monogamous meadow vole. MTII-induced partner preferences were enduring, as they were present 1 week after drug manipulation. The prosocial effects of MCR agonists may be mediated, in part, through modulation of OT, as coadministration of an OT receptor antagonist prevented MTII-induced partner preferences. MTII also selectively activated hypothalamic OT neurons and potentiated central OT release. As OT has been shown to enhance some aspects of social cognition in humans, our data suggest that the MC4R may be a viable therapeutic target for enhancing social function in psychiatric disorders, including autism spectrum disorders and schizophrenia, potentially through activation of the OT system.

  17. The relationship between demand and need for orthodontic treatment in high school students in Bangkok.

    Science.gov (United States)

    Atisook, Pitraporn; Chuacharoen, Rattiya

    2014-07-01

    Orthodontic service is limited in Thailand and cannot meet the demand of the population. (1) To assess the need for orthodontic treatment (OT) using the Index of Orthodontic Treatment Need (IOTN) to analyze the relationship between demand and need for OT and (2) to compare the demand and need for OT between genders. A cross-sectional study was conducted on 450 students aged 12- to 14-years-old in three government high schools in Bangkok. A constructed questionnaire was used to assess demand for OT Clinical examination was done by two orthodontists to determine the needfor OT using the IOTN RESULTS: Most of the students (74.0%) wished to have OT while only one-third (37.5%) had severe need, and one-third (34.4%) had moderate need for OT as judge by the DHC of the IOTN. The AC of the IOTN indicated that most students (55.8%) had mild or no need for OT Females (79%) demanded OT more than males (66% p-value = 0.033) but the need was similar in both sexes. Most functional factors had strong relationships with the demand for OTexcept lower teeth bite on palate, but none was found to be associated with need for OT All of the aesthetic factors had strong relationships with demand for OT There were significant relationships with needs in five categories, 1) crooked, crowded, or spacing teeth, 2) worried when speaking or smiling, 3) had suggestedfor OT 4) breath smell and halitosis, and 5) wanted to put on braces to be like other people or for fashionable reasons. Most of the students requested OT but females had significantly higher demand for OT than males. Most of the samples needed to have OT The aesthetic factors that had strong relationships with the need for OT were 1) crooked, crowded, or spacing teeth, 2) worried when speaking or smiling, 3) had suggested for T07 4) breath smell and halitosis, and 5) wanted to put on braces to be like otherpeople orfor fashionable reasons.

  18. Oxytocin and prolactin release after hypertonic saline administration in melatonin-treated male Syrian hamsters

    International Nuclear Information System (INIS)

    Juszczak, M.; Steger, R.W.; Fadden, C.; Bartke, A.

    1996-01-01

    The aim of the present investigations was to examine the effects of melatonin (Mel) on oxytocin (OT) release under conditions of osmotic stimulation, brought about by hypertonic saline administration, as well as to determine whether osmotically stimulated OT release in Mel-treated Syrian hamster is associated with alterations in the release of prolactin (PRL) and in norepinephrine (NE) and dopamine (DA) content in the hypothalamus. In both Mel- and vehicle-treated hamsters, injection of hypertonic saline was followed by a significant decrease in OT content in the pituitary neurointermediate lobe (NIL) and elevation of plasma OT and PRL levels. Melatonin injections had no significant affect on NIL OT content in either isotonic- or hypertonic-saline treated animals. Pretreatment with Mel did not alter plasma OT or PRL levels in isotonic saline-injected animals. However, Mel facilitated the release of OT, but prevented the release of PRL after hypertonic saline administration. Melatonin treatment reduced hypothalamic NE content (but not that of DA) in isotonic-saline treated animals. After osmotic stimulation, hypothalamic content of NE and DA was significantly lower in Mel-treated than in vehicle-treated animals. Data from the present study suggest that the osmotically-stimulated release of OT and PRL seems to be related to the activation of noradrenergic rather than dopaminergic transmission. Both dopaminergic and noradrenergic transmission may be, however, involved in mediating the effects of Mel on the osmotically-activated OT and PRL release. (author). 48 refs, 3 figs

  19. Oxytocin increases amygdala reactivity to threatening scenes in females.

    Science.gov (United States)

    Lischke, Alexander; Gamer, Matthias; Berger, Christoph; Grossmann, Annette; Hauenstein, Karlheinz; Heinrichs, Markus; Herpertz, Sabine C; Domes, Gregor

    2012-09-01

    The neuropeptide oxytocin (OT) is well known for its profound effects on social behavior, which appear to be mediated by an OT-dependent modulation of amygdala activity in the context of social stimuli. In humans, OT decreases amygdala reactivity to threatening faces in males, but enhances amygdala reactivity to similar faces in females, suggesting sex-specific differences in OT-dependent threat-processing. To further explore whether OT generally enhances amygdala-dependent threat-processing in females, we used functional magnetic resonance imaging (fMRI) in a randomized within-subject crossover design to measure amygdala activity in response to threatening and non-threatening scenes in 14 females following intranasal administration of OT or placebo. Participants' eye movements were recorded to investigate whether an OT-dependent modulation of amygdala activity is accompanied by enhanced exploration of salient scene features. Although OT had no effect on participants' gazing behavior, it increased amygdala reactivity to scenes depicting social and non-social threat. In females, OT may, thus, enhance the detection of threatening stimuli in the environment, potentially by interacting with gonadal steroids, such as progesterone and estrogen. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. A common oxytocin receptor gene (OXTR) polymorphism modulates intranasal oxytocin effects on the neural response to social cooperation in humans.

    Science.gov (United States)

    Feng, C; Lori, A; Waldman, I D; Binder, E B; Haroon, E; Rilling, J K

    2015-09-01

    Intranasal oxytocin (OT) can modulate social-emotional functioning and related brain activity in humans. Consequently, OT has been discussed as a potential treatment for psychiatric disorders involving social behavioral deficits. However, OT effects are often heterogeneous across individuals. Here we explore individual differences in OT effects on the neural response to social cooperation as a function of the rs53576 polymorphism of the oxytocin receptor gene (OXTR). Previously, we conducted a double-blind, placebo-controlled study in which healthy men and women were randomized to treatment with intranasal OT or placebo. Afterwards, they were imaged with functional magnetic resonance imaging while playing an iterated Prisoner's Dilemma Game with same-sex partners. Within the left ventral caudate nucleus, intranasal OT treatment increased activation to reciprocated cooperation in men, but tended to decrease activation in women. Here, we show that these sex differences in OT effects are specific to individuals with the rs53576 GG genotype, and are not found for other genotypes (rs53576 AA/AG). Thus, OT may increase the reward or salience of positive social interactions for male GG homozygotes, while decreasing those processes for female GG homozygotes. These results suggest that rs53576 genotype is an important variable to consider in future investigations of the clinical efficacy of intranasal OT treatment. © 2015 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  1. Oxytocin Removes Estrous Female vs. Male Preference of Virgin Male Rats: Mediation of the Supraoptic Nucleus Via Olfactory Bulbs

    Directory of Open Access Journals (Sweden)

    Xiao-Yu Liu

    2017-10-01

    Full Text Available Social functions of oxytocin (OT have been explored extensively; however, relationship between the effect of intranasally applied OT (nasal OT on the social preference (SP and intracerebral actions of endogenous OT remains unclear. To resolve this question, we first observed effects of nasal OT on the SP of virgin young adult male rats toward unfamiliar virgin estrous female (EF vs. virgin male rats. The results showed that the test male rats exhibited significantly more times and longer duration accessing the female than the male, which were acutely eliminated by nasal OT. Then, we examined the approaches mediating nasal OT effects on the activity of potential brain targets in Western blots and found that nasal OT activated the olfactory bulbs (OBs and the supraoptic nucleus (SON, but not the piriform cortex, amygdala and hippocampus as shown by significant changes in the expression of c-Fos and/or phosphorylated extracellular signal-regulated protein kinase (pERK 1/2. Moreover, microinjection of TTX into the OBs blocked nasal OT-evoked increases in pERK1/2 levels as well as the molecular association between ERK1/2 and OT-neurophysin in the SON. Electrolytic lesions of the lateral olfactory tract did not significantly change the basal levels of pERK 1/2 in the SON; however, upon nasal OT, pERK 1/2 levels in the SON reduced significantly. Lastly, microinjection of L-aminoadipic acid (gliotoxin into the SON to reduce OT levels reduced the duration of the test male’s accessing the EF and blocked the nasal OT-evoked increase in the duration of test male’s accessing the male while significantly increasing pERK1/2 levels in the amygdala. These findings reveal for the first time that nasal OT acutely eliminates virgin males’ SP to EFs via the OB-SON route and that OT neurons could mediate the social effects of nasal OT by suppressing social phobia generated in the amygdala.

  2. Oxytocin and Aggression.

    Science.gov (United States)

    de Jong, Trynke R; Neumann, Inga D

    2017-09-02

    The neuropeptide oxytocin (OT) has a solid reputation as a facilitator of social interactions such as parental and pair bonding, trust, and empathy. The many results supporting a pro-social role of OT have generated the hypothesis that impairments in the endogenous OT system may lead to antisocial behavior, most notably social withdrawal or pathological aggression. If this is indeed the case, administration of exogenous OT could be the "serenic" treatment that psychiatrists have for decades been searching for.In the present review, we list and discuss the evidence for an endogenous "hypo-oxytocinergic state" underlying aggressive and antisocial behavior, derived from both animal and human studies. We furthermore examine the reported effects of synthetic OT administration on aggression in rodents and humans.Although the scientific findings listed in this review support, in broad lines, the link between a down-regulated or impaired OT system activity and increased aggression, the anti-aggressive effects of synthetic OT are less straightforward and require further research. The rather complex picture that emerges adds to the ongoing debate questioning the unidirectional pro-social role of OT, as well as the strength of the effects of intranasal OT administration in humans.

  3. The Mediating Role of Organizational Trust on The Effects of Servant Leader ship and Organizational Justice on Organizational Identification

    Directory of Open Access Journals (Sweden)

    Fikret Ateş

    2015-09-01

    Full Text Available The aim of this study determined to research whether was affected Organizational Identification (OI by Servant Leadership (SL, Organizational Justice (OJ, Organizational Trust (OT and, how was affected OI by SL and OJ and, whether there is an indirecteffect of OT on the relations of OI-SL and OI-OJ. For these aims, the questionnaire was developed with Dennis and Bocerne (2006's SL scale, Colquitt (2001's OJ scale, Mael and Ashforth (1992's OI scale, Bromiley and Cummings (1996’s OT scale. The validity of scales authenticated with multi-factor structure for SL, OJ, and OT, with one factor structure for OI. The reliability of scales were calculated as Cronbach's alpha (α values (SL=0.95; OJ=0.93, OT=0.76, OI=0.87. According to the hypothesis tests which done by Structural Equation Models; has that there are direct positive effects between SL, OJ, OT and OI or between SL, OJ and OT; finally has determined that there are positive and partial indirect effects between OT and SL-OI or between OT andOJ-OI.

  4. Scope of practice and supervision of orthodontic therapists in the United Kingdom: Part 2: a national cross-sectional survey of orthodontic therapists.

    Science.gov (United States)

    Ahmed, Farooq; Dugdale, Charlotte; Malik, Ovais; Waring, David

    2018-03-01

    Orthodontic therapists (OTs) are the most recent addition to the orthodontic clinical team. The General Dental Council (GDC) and the British Orthodontic Society have formulated guidance and guidelines relating to their scope of practice and level of supervision, however there has been no contemporary UK-based research investigating practice and supervision of OTs. The aim of this study was to investigate the scope of practice and level of supervision of OTs working in the UK. Ethical approval was received from the University of Manchester Research Ethics Committee. An anonymous postal questionnaire was dispatched using postal details acquired through the British Orthodontic Societies mailing list. Three mailings of the questionnaire were conducted. A 74% response rate was achieved. OTs routinely conducted 16 of the 20 procedures from their scope of practice. Uncommon procedures included fitting headgear (24%), lingual appliances (27%), inserting or removing temporary anchorage devices (20%), and taking facebow record (18%). A total of 62% of OTs took patient consent for treatment. 59% were supervised through a written prescription with no direct supervision. OTs were directly supervised for only a quarter of their clinical practice. Orthodontists viewing frequency for OTs varied significantly, and was found to be the following: every 2-4 visits (36%), every other visit (35%), and every visit (26%). OTs mostly carried out the scope of practice as permitted by the GDC. Procedures uncommon to routine orthodontic practice were also uncommon to Orthodontic therapist clinical practice. OTs work mostly through written prescription with no direct supervision.

  5. The knowledge and attitudes of orthodontic trainees towards orthodontic therapists: a national survey.

    Science.gov (United States)

    Patel, Sameer; Mack, Gavin

    2017-09-01

    To assess the knowledge and attitudes of orthodontic trainees towards orthodontic therapists (OTs) in the UK. Cross-sectional survey. UK-based orthodontic trainees. An electronic survey was sent to all members of the Training Grades Group of the British Orthodontic Society assessing exposure to OTs and their knowledge regarding current supervision guidelines and scope of practice. Attitudes towards OTs were also explored. Seventy-six responses (response rate 57%) were returned. Nearly 90% of trainees had no formal training regarding OTs. A total of 15.5% were aware of the correct current supervision guidelines and there was large variation in the knowledge of OTs' scope of practice. The majority of trainees were happy to supervise OTs, but only 22.4% felt prepared for this during training. In total, 63% of trainees felt that OTs could impact their own future job prospects. Currently, there is minimal formal training provided to trainees regarding the role of OTs. This is reflected in the lack of knowledge regarding supervision guidelines and scope of practice. Overall, trainees felt OTs were positive for the workforce but were concerned regarding the impact of their own future employment.

  6. Oxytocin facilitates fidelity in well-established marmoset pairs by reducing sociosexual behavior toward opposite-sex strangers.

    Science.gov (United States)

    Cavanaugh, Jon; Mustoe, Aaryn C; Taylor, Jack H; French, Jeffrey A

    2014-11-01

    Behavioral strategies that facilitate the maintenance of social bonds are critical for the preservation of high-quality social relationships. Central oxytocin (OT) activity modulates the behavioral features of socially monogamous relationships in a number of mammalian species (including marmoset monkeys), and plays a vital role in the behavioral maintenance of long-term social relationships. Two distinct variants of OT have been identified in some New World primates (including marmosets; Lee et al., 2011). The marmoset variant of the oxytocin ligand (Pro(8)-OT) is structurally distinct from the consensus mammalian variant of the oxytocin ligand (Leu(8)-OT), due to a proline substitution at the 8th amino-acid position. The goal of the present study was to determine if treating marmosets with Pro(8)-OT, relative to treatments with Leu(8)-OT, control saline, or an OT antagonist, had modulatory effects on the behavioral maintenance of long-term social relationships in marmosets. Treatment with the Pro(8) variant, but not the Leu(8) variant, of OT facilitated fidelity with a long-term partner by reducing time spent in close proximity with an opposite-sex stranger. However, this facilitative effect of Pro(8)-OT on proximity behavior manifested itself differently in male and female marmosets, such that females preferred to interact socially with their partner rather than a stranger when treated with Pro(8)-OT, while males spent less time in close proximity with both their partner and a stranger when treated with Pro(8)-OT. Furthermore, treatment with Pro(8)-OT, but not Leu(8)-OT, significantly delayed the expression of sexual solicitation behavior toward an opposite-sex stranger in both male and female marmosets, but had no effect on sociosexual behavior directed toward a long-term partner. These results suggest that the OT system is highly involved in reducing fidelity-threatening behaviors in well-established marmoset pairs, and that the effects were only produced by

  7. Corticotropin-Releasing Factor Receptors Modulate Oxytocin Release in the Dorsolateral Bed Nucleus of the Stria Terminalis (BNST in Male Rats

    Directory of Open Access Journals (Sweden)

    Daisy Martinon

    2018-03-01

    Full Text Available The neuropeptide oxytocin (OT plays an important role in the regulation of social and anxiety-like behavior. Our previous studies have shown that OT neurons send projections from the hypothalamus to the dorsolateral bed nucleus of the stria terminalis (BNSTdl, a forebrain region critically involved in the modulation of anxiety-like behavior. Importantly, these OT terminals in the BNSTdl express presynaptic corticotropin releasing factor (CRF receptor type 2 (CRFR2. This suggests that CRFR2 might be involved in the modulation of OT release. To test this hypothesis, we measured OT content in microdialysates collected from the BNSTdl of freely-moving male Sprague-Dawley rats following the administration of a selective CRFR2 agonist (Urocortin 3 or antagonist (Astressin 2B, As2B. To determine if type 1 CRF receptors (CRFR1 are also involved, we used selective CRFR1 antagonist (NBI35965 as well as CRF, a putative ligand of both CRFR1 and CRFR2. All compounds were delivered directly into the BNSTdl via reverse dialysis. OT content in the microdialysates was measured with highly sensitive and selective radioimmunoassay. Blocking CRFR2 with As2B caused an increase in OT content in BNSTdl microdialysates, whereas CRFR2 activation by Urocortin 3 did not have an effect. The As2B-induced increase in OT release was blocked by application of the CRFR1 antagonist demonstrating that the effect was dependent on CRFR1 transmission. Interestingly, CRF alone caused a delayed increase in OT content in BNSTdl microdialysates, which was dependent on CRF2 but not CRF1 receptors. Our results suggest that members of the CRF peptide family modulate OT release in the BNSTdl via a fine-tuned mechanism that involves both CRFR1 and CRFR2. Further exploration of mechanisms by which endogenous OT system is modulated by CRF peptide family is needed to better understand the role of these neuropeptides in the regulation of anxiety and the stress response.

  8. Orthostatic Tremor and Orthostatic Myoclonus: Weight-bearing Hyperkinetic Disorders: A Systematic Review, New Insights, and Unresolved Questions

    Directory of Open Access Journals (Sweden)

    Anhar Hassan

    2016-11-01

    Full Text Available Background: Orthostatic tremor (OT and orthostatic myoclonus (OM are weight-bearing hyperkinetic movement disorders most commonly affecting older people that induce “shaky legs” upon standing. OT is divided into “classical” and “slow” forms based on tremor frequency. In this paper, the first joint review of OT and OM, we review the literature and compare and contrast their demographic, clinical, electrophysiological, neuroimaging, pathophysiological, and treatment characteristics. Methods: A PubMed search up to July 2016 using the phrases “orthostatic tremor,” “orthostatic myoclonus,” “shaky legs,” and “shaky legs syndrome” was performed. Results: OT and OM should be suspected in older patients reporting unsteadiness with prolonged standing and/or who exhibit cautious, wide-based gaits. Surface electromyography (SEMG is necessary to verify the diagnoses. Functional neuroimaging and electrophysiology suggest the generator of classical OT lies within the cerebellothalamocortical network. For OM, and possibly slow OT, the frontal, subcortical cerebrum is the most likely origin. Clonazepam is the most useful medication for classical OT, and levetiracetam for OM, although results are often disappointing. Deep brain stimulation appears promising for classical OT. Rolling walkers reliably improve gait affected by these disorders, as both OT and OM attenuate when weight is transferred from the legs to the arms. Discussion: Orthostatic hyperkinesias are likely underdiagnosed, as SEMG is often unavailable in clinical practice, and thus may be more frequent than currently recognized. The shared weight-bearing induction of OT and OM may indicate a common pathophysiology. Further research, including use of animal models, is necessary to better define the prevalence and pathophysiology of OT and OM, in order to improve their treatment, and provide additional insights into basic balance and gait mechanisms.

  9. Conditioned social preference, but not place preference, produced by intranasal oxytocin in female mice.

    Science.gov (United States)

    Kosaki, Yutaka; Watanabe, Shigeru

    2016-04-01

    Oxytocin (OT) has been implicated in a variety of mammalian reproductive and social behaviors, and the use of intranasal OT for clinical purposes is on the rise. However, basic actions of OT, including the rewarding or reinforcing properties of the drug, are currently not fully understood. In this study, the authors investigated whether intranasally administered OT has different reinforcing properties for social and nonsocial stimuli and whether such effects are variable between male and female subjects. Conditioned social preference (CSP) and conditioned place preference (CPP) paradigms were used to examine social and nonsocial reinforcing properties of OT. In CSP, the presence of a same-sex unfamiliar conspecific was repeatedly paired with intranasal OT, while a different conspecific was associated with saline. The reinforcing effect of OT was assessed in a postconditioning choice test under a drug-free condition. In CPP, the 2 conspecifics were replaced with nonsocial black and white compartments. The authors found that intranasal OT (12 μg) in females supported the formation of CSP (Experiment 1) but not CPP (Experiment 3). Neither CSP (Experiment 2) nor CPP (Experiment 4) was formed in males. Extended conditioning with higher dose OT (36 μg), however, abolished the initial CSP in females and produced an aversion to the OT-paired stimulus mouse. Experiment 5 indicated that it was the repeated administrations rather than the higher dose that produced the abolition of the original preference. Overall, the current results demonstrate for the first time a sex- and stimulus-dependent reinforcing property of intranasal OT in mice. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  10. Long-term exposure to intranasal oxytocin in a mouse autism model.

    Science.gov (United States)

    Bales, K L; Solomon, M; Jacob, S; Crawley, J N; Silverman, J L; Larke, R H; Sahagun, E; Puhger, K R; Pride, M C; Mendoza, S P

    2014-11-11

    Oxytocin (OT) is a neuropeptide involved in mammalian social behavior. It is currently in clinical trials for the treatment of autism spectrum disorder (ASD). Previous studies in healthy rodents (prairie voles and C57BL/6J mice) have shown that there may be detrimental effects of long-term intranasal administration, raising the questions about safety and efficacy. To investigate the effects of OT on the aspects of ASD phenotype, we conducted the first study of chronic intranasal OT in a well-validated mouse model of autism, the BTBR T+ Itpr3tf/J inbred strain (BTBR), which displays low sociability and high repetitive behaviors. BTBR and C57BL/6J (B6) mice (N=94) were administered 0.8  IU/kg of OT intranasally, daily for 30 days, starting on day 21. We ran a well-characterized set of behavioral tasks relevant to diagnostic and associated symptoms of autism, including juvenile reciprocal social interactions, three-chambered social approach, open-field exploratory activity, repetitive self-grooming and fear-conditioned learning and memory, some during and some post treatment. Intranasal OT did not improve autism-relevant behaviors in BTBR, except for female sniffing in the three-chambered social interaction test. Male saline-treated BTBR mice showed increased interest in a novel mouse, both in chamber time and sniffing time, whereas OT-treated male BTBR mice showed a preference for the novel mouse in sniffing time only. No deleterious effects of OT were detected in either B6 or BTBR mice, except possibly for the lack of a preference for the novel mouse's chamber in OT-treated male BTBR mice. These results highlight the complexity inherent in understanding the effects of OT on behavior. Future investigations of chronic intranasal OT should include a wider dose range and early developmental time points in both healthy rodents and ASD models to affirm the efficacy and safety of OT.

  11. Antinociceptive action of oxytocin involves inhibition of potassium channel currents in lamina II neurons of the rat spinal cord

    Directory of Open Access Journals (Sweden)

    Darbon Pascal

    2009-11-01

    Full Text Available Abstract Background Growing evidence in the literature shows that oxytocin (OT has a strong spinal anti-nociceptive action. Oxytocinergic axons originating from a subpopulation of paraventricular hypothalamic neurons establish synaptic contacts with lamina II interneurons but little is known about the functional role of OT with respect to neuronal firing and excitability. Results Using the patch-clamp technique, we have recorded lamina II interneurons in acute transverse lumbar spinal cord slices of rats (15 to 30 days old and analyzed the OT effects on action potential firing ability. In the current clamp mode, we found that bath application of a selective OT-receptor agonist (TGOT reduced firing in the majority of lamina II interneurons exhibiting a bursting firing profile, but never in those exhibiting a single spike discharge upon depolarization. Interestingly, OT-induced reduction in spike frequency and increase of firing threshold were often observed, leading to a conversion of the firing profile from repetitive and delayed profiles into phasic ones and sometimes further into single spike profile. The observed effects following OT-receptor activation were completely abolished when the OT-receptor agonist was co-applied with a selective OT-receptor antagonist. In current and voltage clamp modes, we show that these changes in firing are strongly controlled by voltage-gated potassium currents. More precisely, transient IA currents and delayed-rectifier currents were reduced in amplitude and transient IA current was predominantly inactivated after OT bath application. Conclusion This effect of OT on the firing profile of lamina II neurons is in good agreement with the antinociceptive and analgesic properties of OT described in vivo.

  12. Cuban Ocular Toxoplasmosis Epidemiology Study (COTES): incidence and prevalence of ocular toxoplasmosis in Central Cuba.

    Science.gov (United States)

    Bustillo, Jorge L; Diaz, Jose D; Pacheco, Idarmes C; Gritz, David C

    2015-03-01

    Serological studies indicate that rates of ocular toxoplasmosis (OT) vary geographically, with higher rates in tropical regions. Little is known about population-based rates of active OT. We aimed to describe the epidemiology of OT in Central Cuba. This large-population, cross-sectional cohort study used a prospective database at a large regional referral centre in Central Cuba. The patient database was searched for all patients who presented with OT during the 12-month study period from 1 April 2011 to 31 March 2012. Inclusion criteria were the clinical diagnosis of OT, characterised by focal retinochoroidal inflammation and a response to therapy as expected. Gender-stratified and age-stratified study population data from the 2012 Cuban Census were used to calculate incidence rates and prevalence ratios. Among 279 identified patients with OT, 158 presented with active OT. Of these, 122 new-onset and 36 prior-onset cases were confirmed. Based on the total population in the Sancti Spiritus province (466,106 persons), the overall incidence of active OT was 26.2 per 100,000 person-years (95% CI 21.7 to 31.3) with an annual prevalence ratio of 33.9 per 100,000 persons (95% CI 28.8 to 39.6). The incidence of active OT was lowest in the oldest age group and highest in patients aged 25-44 years (4.5 and 42.1 per 100,000 person-years, respectively). This first report describing population-based rates of OT in the Cuban population highlights the importance of patient age as a likely risk factor for OT. Disease rates were found to be highest in females and young to middle-aged adults. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  13. Termiškai aktyvių membraninių tekstilės medžiagų plazminis apdorojimas siekiant superhidrofobiškumo

    Directory of Open Access Journals (Sweden)

    Adam TWARDOWSKI

    2012-06-01

    Full Text Available Specialios paskirties lauko drabužiai turi atitikti aukštus patvarumo, šiluminės ištaigos ir drėgmės pernašos reikalavimus. Šiems tikslams dažnai naudojamos membraninės termiškai aktyvios tekstilės medžiagos. Siekiant pagerinti šių tekstilės medžiagų išvaizda, gali būti naudojami įvairūs poveikiai, užtikrinantys superhidrofobinį savaime besivalantį paviršių (žinomą kaip lotoso efektas. Įgyvendinant šią idėją, buvo atlikti žėrinčiojo išlydžio radijo dažnio inertinių dujų bei angliavandenilių dujų plazmos poveikio pramoninėms medžiagoms tyrimai. Gauti geri rezultatai tiriant savaiminio valymosi savybes empiriškai, tam naudojant dulkes ir kietąsias daleles. Skirtingos poveikio sąlygos buvo lyginamos matuojant kontaktinį vandens drėkinimo kampą. Daugeliu atvejų paveiktų medžiagų kontaktinis kampas buvo gerokai didesnis nei pradinių medžiagų. Didžiausia kampo vertė siekė 155°. Paviršiaus ištirtas naudojant skenuojamąjį elektroninį mikroskopą (SEM bei SEM-EDX spektroskopiją. Silikoorganinių dujų plazma apdoroto pluošto paviršiuje aptiktas plonas būdingos sferinės struktūros sluoksnis.DOI: http://dx.doi.org/10.5755/j01.ms.18.2.1920

  14. MATERNAL MENTAL HEALTH MODERATES THE RELATIONSHIP BETWEEN OXYTOCIN AND INTERACTIVE BEHAVIOR.

    Science.gov (United States)

    Samuel, Simcha; Hayton, Barbara; Gold, Ian; Feeley, Nancy; Carter, C Sue; Zelkowitz, Phyllis

    2015-01-01

    Mothers with mood or anxiety disorders exhibit less optimal interactive behavior. The neuropeptide oxytocin (OT) has been linked to more optimal interactive behaviors in mothers without mental illness, and it may play a particularly beneficial role in mothers with mood or anxiety disorders given its antidepressant and anxiolytic functions. We compared the relationship between OT and interactive behavior in mothers with and without mental health problems. Participants included 20 women diagnosed with postpartum mood or anxiety disorders (clinical sample) and 90 women with low levels of depression and anxiety during pregnancy and postpartum (community sample). At 2 months' postpartum, blood was drawn to assess maternal OT levels, and mother-infant interaction was coded for maternal sensitivity, intrusiveness, remoteness, and depressiveness. Clinical mothers exhibited less sensitive, more intrusive, and more depressive interactive behaviors than did community mothers. The groups did not differ in OT levels. Mothers with higher OT levels were less intrusive with their infants. Higher OT levels were associated with less depressive interactive behavior only in clinical mothers. OT was associated with positive interactive behaviors in both groups. In clinical mothers, the calming and soothing effects of OT may promote more relaxed, energetic, and infant-focused interactive behaviors. © 2015 Michigan Association for Infant Mental Health.

  15. 4-Oxalocrotonate tautomerase, its homologue YwhB, and active vinylpyruvate hydratase : Synthesis and evaluation of 2-fluoro substrate analogues

    NARCIS (Netherlands)

    Johnson, William H; Wang, Susan C; Stanley, Thanuja M; Czerwinski, Robert M; Almrud, Jeffrey J; Poelarends, Gerrit J; Murzin, Alexey G; Whitman, Christian P

    2004-01-01

    A series of 2-fluoro-4-alkene and 2-fluoro-4-alkyne substrate analogues were synthesized and examined as potential inhibitors of three enzymes: 4-oxalocrotonate tautomerase (4-OT) and vinylpyruvate hydratase (VPH) from the catechol meta-fission pathway and a closely related 4-OT homologue found in

  16. Instructional Strategies Used to Improve Students' Comfort and Skill in Addressing the Occupational Therapy Process

    Science.gov (United States)

    Knecht-Sabres, Lisa Jean; Egan, Brad E.; Wallingford, Minetta S.; Kovic, Mark

    2015-01-01

    The purpose of this study was to investigate the effectiveness of an intentional blending of instructional strategies in an occupational therapy (OT) entry-level master's course. The OT Adult Practice course uses case-based instructional strategies, clinical skills labs, and standardized patient experiences in a dovetailed approach across three…

  17. Patient compliance with a health care provider referral for an occupational therapy lymphedema consult.

    Science.gov (United States)

    Dominick, Sally A; Natarajan, Loki; Pierce, John P; Madanat, Hala; Madlensky, Lisa

    2014-07-01

    Limited information exists on breast cancer patients' compliance to attend outpatient appointments with an occupational therapy (OT) lymphedema specialist. The objectives of this study were (1) to examine patient compliance with a health care provider referral for an OT lymphedema consult and (2) to identify potential barriers to compliance. A retrospective chart review of female breast cancer patients at the UC San Diego Health System was conducted. Electronic medical records were queried for breast cancer patients, who received a health care provider referral for an OT lymphedema consult between June 1, 2010 and December 31, 2011. Descriptive statistics and Fisher's exact chi-square tests were used to examine how specific participant characteristics were associated with attending an OT appointment. A total of 210 female patients received an OT referral from a health care provider related to their breast cancer diagnosis. Forty-three (20.5%) patients did not attend an OT appointment. Non-attenders were more likely to have had fewer lymph nodes removed (Pcancer patients attended recommended OT lymphedema consults, a substantial number of women might benefit from further education about OT for lymphedema prevention following breast cancer treatment. Further research to understand barriers to attendance is recommended, particularly among women with only sentinel nodes removed.

  18. 76 FR 7243 - Privacy Act of 1974, as Amended; System of Records

    Science.gov (United States)

    2011-02-09

    ... Security and Governmental Affairs of the Senate, and the Office of Management and Budget, pursuant to... employees who retire from OTS and have the OTS sponsored life insurance. The system is used by Payroll... with the Financial Management Services (FMS), which is another bureau of the Treasury Department, so...

  19. 32 CFR 3.9 - Follow-on production contracts.

    Science.gov (United States)

    2010-07-01

    ...) Use competition to select parties for participation in the OT prototype agreement and evaluate the... THAN CONTRACTS, GRANTS, OR COOPERATIVE AGREEMENTS FOR PROTOTYPE PROJECTS § 3.9 Follow-on production contracts. (a) Authority. A competitively awarded OT agreement for a prototype project that satisfies the...

  20. Nanolithography and nanochemistry utilizing scanning probe techniques: directed self-assembly of sub-micrometer-sized structures by scanning probe lithography defined templates

    NARCIS (Netherlands)

    Wouters, D.; Sturms, J.P.E.; Schubert, U.S.

    2004-01-01

    The octadecyl trichlorosilane (OTS) monolayer was formed on Si carrier, and the template regulated by a local probe oxidation method from this was produced using a scanning probe lithography. The local probe oxidation was done by moving an AFM tip along an axle line. When the chip contacts a OTS

  1. 75 FR 7925 - Unfair or Deceptive Acts or Practices

    Science.gov (United States)

    2010-02-22

    ... rules issued by the Office of Thrift Supervision (OTS) and the National Credit Union Administration... Rule jointly with a rule issued by the Office of Thrift Supervision (OTS) amending 12 CFR Part 535 and... Part 227 Banks, Banking, Credit, Intergovernmental relations, Trade practices. Board of Governors of...

  2. A. D. DE APOSTOLISCHE KERK. Theologische Bijdragen ter ...

    African Journals Online (AJOL)

    Test

    Dr. J. Ridderbos open die ry van artikels met 'n beskouing oor Oud en Nieuui Verbond. Vanuit die voor-apostoliese O.T. gee die skrywer 'n uiteensetting van die verbondenheid tussen O.T. en N.T. en wil daarop wys dat die apostoliese openbaring steeds nou verbind was aan die ou bedeling (blz. 7). Hierdie artikel is een ...

  3. Occupational therapy for stroke patients - A systematic review

    NARCIS (Netherlands)

    Steultjens, E.M.J.; Dekker, J.; Bouter, L.M.; van de Nes, J.C.M.; Cup, E.H.C.; van den Ende, C.H.M.

    2003-01-01

    Background and Purpose - Occupational therapy (OT) is an important aspect of stroke rehabilitation. The objective of this study was to determine from the available literature whether OT interventions improve outcome for stroke patients. Methods - An extensive search in MEDLINE, CINAHL, EMBASE, AMED,

  4. A New Observing Tool for the James Clerk Maxwell Telescope

    Science.gov (United States)

    Folger, Martin; Bridger, Alan; Dent, Bill; Kelly, Dennis; Adamson, Andy; Economou, Frossie; Hirst, Paul; Jenness, Tim

    A new Observing Tool (OT) has been developed at the UK Astronomy Technology Centre, Edinburgh, UK and the Joint Astronomy Centre, Hilo, Hawaii, USA. It is based on the Gemini Observing Tool and provides the first graphical observation preparation tool for the James Clerk Maxwell Telescope (JCMT) as well as being the first use of the OT for a non-optical/IR telescope. The OT allows the observer to assemble high level Science Programs using graphical representations of observation components such as instrument, target, and filter. This is later translated into low level control sequences for telescope and instruments. The new OT is designed to work on multiple telescopes: currently the UK Infrared Telescope (UKIRT) and JCMT. Object-oriented design makes the inclusion of telescope and instrument specific packages easy. The OT is written in Java using GUI packages such as Swing and JSky. A new component for the JCMT OT is the graphical Frequency Editor for Heterodyne instruments. It can be used to specify parameters such as frequencies, bandwidths, and sidebands of multiple subsystems, while graphically displaying the front-end frequency, emission lines and atmospheric transmission. In addition, Flexible Scheduling support has been added to the OT. The observer can define scheduling constraints by arranging observations graphically. Science Programs can be saved as XML or sent directly from the OT to a database (via SOAP).

  5. Concentration of Antifouling Biocides and Metals in Sediment Core Samples in the Northern Part of Hiroshima Bay

    Directory of Open Access Journals (Sweden)

    Noritaka Tsunemasa

    2014-06-01

    Full Text Available Accumulation of Ot alternative antifoulants in sediment is the focus of this research. Much research had been done on surface sediment, but in this report, the accumulation in the sediment core was studied. The Ot alternative antifoulants, Diuron, Sea-Nine211, and Irgarol 1051, and the latter’s degradation product, M1, were investigated in five samples from the northern part of Hiroshima Bay. Ot compounds (tributyltin (TBT and triphenyltin (TPT were also investigated for comparison. In addition, metal (Pb, Cu, Zn, Fe and Mn levels and chronology were measured to better understand what happens after accumulation on the sea floor. It was discovered that Ot alternative antifoulant accumulation characteristics in sediment were like Ot compounds, with the concentration in the sediment core being much higher than surface sediment. The concentration in sediment seems to have been affected by the regulation of Ot compounds in 1990, due to the concentration of Ot alternative antifoulants and Ot compounds at the survey point in front of the dock, showing an increase from almost the same layer after the regulation.

  6. Organotins in Neuronal Damage, Brain Function, and Behavior: A Short Review

    Directory of Open Access Journals (Sweden)

    Igor Ferraz da Silva

    2018-01-01

    Full Text Available The consequences of exposure to environmental contaminants have shown significant effects on brain function and behavior in different experimental models. The endocrine-disrupting chemicals (EDC present various classes of pollutants with potential neurotoxic actions, such as organotins (OTs. OTs have received special attention due to their toxic effects on the central nervous system, leading to abnormal mammalian neuroendocrine axis function. OTs are organometallic pollutants with a tin atom bound to one or more carbon atoms. OT exposure may occur through the food chain and/or contaminated water, since they have multiple applications in industry and agriculture. In addition, OTs have been used with few legal restrictions in the last decades, despite being highly toxic. In addition to their action as EDC, OTs can also cross the blood–brain barrier and show relevant neurotoxic effects, as observed in several animal model studies specifically involving the development of neurodegenerative processes, neuroinflammation, and oxidative stress. Thus, the aim of this short review is to summarize the toxic effects of the most common OT compounds, such as trimethyltin, tributyltin, triethyltin, and triphenyltin, on the brain with a focus on neuronal damage as a result of oxidative stress and neuroinflammation. We also aim to present evidence for the disruption of behavioral functions, neurotransmitters, and neuroendocrine pathways caused by OTs.

  7. The Effect of Online Translators on L2 Writing in French

    Science.gov (United States)

    O'Neill, Errol Marinus

    2012-01-01

    Online translation (OT) sites such as Free Translation and Babel Fish are freely available to the general public and purport to convert inputted text, from single words to entire paragraphs, instantly from one language to another. Discussion in the literature about OT for second-language (L2) acquisition has generally focused either on the…

  8. Intranasal oxytocin modulates neural functional connectivity during human social interaction.

    Science.gov (United States)

    Rilling, James K; Chen, Xiangchuan; Chen, Xu; Haroon, Ebrahim

    2018-02-10

    Oxytocin (OT) modulates social behavior in primates and many other vertebrate species. Studies in non-primate animals have demonstrated that, in addition to influencing activity within individual brain areas, OT influences functional connectivity across networks of areas involved in social behavior. Previously, we used fMRI to image brain function in human subjects during a dyadic social interaction task following administration of either intranasal oxytocin (INOT) or placebo, and analyzed the data with a standard general linear model. Here, we conduct an extensive re-analysis of these data to explore how OT modulates functional connectivity across a neural network that animal studies implicate in social behavior. OT induced widespread increases in functional connectivity in response to positive social interactions among men and widespread decreases in functional connectivity in response to negative social interactions among women. Nucleus basalis of Meynert, an important regulator of selective attention and motivation with a particularly high density of OT receptors, had the largest number of OT-modulated connections. Regions known to receive mesolimbic dopamine projections such as the nucleus accumbens and lateral septum were also hubs for OT effects on functional connectivity. Our results suggest that the neural mechanism by which OT influences primate social cognition may include changes in patterns of activity across neural networks that regulate social behavior in other animals. © 2018 Wiley Periodicals, Inc.

  9. Adjuvant occupational therapy for work-related major depression works: randomized trial including economic evaluation

    NARCIS (Netherlands)

    Schene, Aart H.; Koeter, Maarten W. J.; Kikkert, Martijn J.; Swinkels, Jan A.; McCrone, Paul

    2007-01-01

    BACKGROUND: Major depression has far-reaching consequences for work functioning and absenteeism. In most cases depression is treated by medication and clinical management. The addition of occupational therapy (OT) might improve outcome. We determined the cost-effectiveness of the addition of OT to

  10. Akadeemilised osakonnad : klaveriosakond / Ivari Ilja

    Index Scriptorium Estoniae

    Ilja, Ivari, 1959-

    2009-01-01

    2008. a. valmistati ette VII Eesti pianistide konkurss. I preemia saavutas Maksim Štšura, finalistidiplomi Jaan Ots. Helmi Valtmani stipendiumi sai Jaan Kapp, Lord Carlisle'i stipendiumi Mihkel Poll. Yamaha stipendiumikonkursi võitis Maksim Štšura. Holland Music Sessions 2008 stipendiaadid olid: Maksim Štšura ja Jaan Ots.

  11. 12 CFR 563e.27 - Strategic plan.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 5 2010-01-01 2010-01-01 false Strategic plan. 563e.27 Section 563e.27 Banks... for Assessing Performance § 563e.27 Strategic plan. (a) Alternative election. The OTS will assess a... strategic plan if: (1) The savings association has submitted the plan to the OTS as provided for in this...

  12. Selective activation around the left occipito-temporal sulcus for words relative to pictures: Individual variability or false positives?

    NARCIS (Netherlands)

    Wright, Nicholas D.; Mechelli, Andrea; Noppeney, Uta; Veltman, Dick J.; Rombouts, Serge A. R. B.; Glensman, Janice; Haynes, John-Dylan; Price, Cathy J.

    2008-01-01

    We used high-resolution fMRI to investigate claims that learning to read r !sults in greater left occipito-temporal (OT) activation for written words relative to pictures of objects. In tl e first experiment, 9/16 subjects performing a one-back task showed activation in >= 1 left OT voxel for word:

  13. 76 FR 43549 - Office of Thrift Supervision Integration; Dodd-Frank Act Implementation

    Science.gov (United States)

    2011-07-21

    ..., Manager, Disclosure Services and Administrative Operations, Communications Division, (202) 874-5378... abolishes the OTS ninety days after the transfer date. Specifically, the Dodd-Frank Act transfers to the OCC... operation of law.\\3\\ Title III also transfers OTS employees to either the OCC or FDIC, allocated as...

  14. Prenatal stress puzzle, the oxytocin piece: Prenatal stress alters the behaviour and autonomic regulation in piglets, insights from oxytocin

    Science.gov (United States)

    Developmental changes in response to prenatal stressors (PNS) may represent an adaptive strategy to enhance survival traits in the offspring. Yet, PNS could be maladaptive for captive animals, causing anxiety and abnormal social development. Oxytocin (OT) reduces anxiety, whereas OT deficiencies are...

  15. 12 CFR 543.9 - Application for conversion to Federal mutual charter.

    Science.gov (United States)

    2010-01-01

    ..., including the present value of any preference to which such holders are entitled. (c) Action on application... of directors, file an application on forms obtained from OTS. The applicant must submit any financial statements or other information OTS may require. (2) Procedures. An application for conversion filed under...

  16. Non-linear learning in online tutorial to enhance students’ knowledge on normal distribution application topic

    Science.gov (United States)

    Kartono; Suryadi, D.; Herman, T.

    2018-01-01

    This study aimed to analyze the enhancement of non-linear learning (NLL) in the online tutorial (OT) content to students’ knowledge of normal distribution application (KONDA). KONDA is a competence expected to be achieved after students studied the topic of normal distribution application in the course named Education Statistics. The analysis was performed by quasi-experiment study design. The subject of the study was divided into an experimental class that was given OT content in NLL model and a control class which was given OT content in conventional learning (CL) model. Data used in this study were the results of online objective tests to measure students’ statistical prior knowledge (SPK) and students’ pre- and post-test of KONDA. The statistical analysis test of a gain score of KONDA of students who had low and moderate SPK’s scores showed students’ KONDA who learn OT content with NLL model was better than students’ KONDA who learn OT content with CL model. Meanwhile, for students who had high SPK’s scores, the gain score of students who learn OT content with NLL model had relatively similar with the gain score of students who learn OT content with CL model. Based on those findings it could be concluded that the NLL model applied to OT content could enhance KONDA of students in low and moderate SPK’s levels. Extra and more challenging didactical situation was needed for students in high SPK’s level to achieve the significant gain score.

  17. Odontogenic Tumors: A Review of 675 Cases in Eastern Libya

    African Journals Online (AJOL)

    Aims: The aim of this study was to determine the relative frequency of odontogenic tumors (OTs) in an Eastern Libyan population based on the 2005 World Health Organization (WHO) classification, and also to compare the actual data with previous studies. Materials and Methods: We retrieved and analyzed 85 OTs from a ...

  18. The Impact of Acquisition Issues and Training on Test and Evaluation

    Science.gov (United States)

    2000-01-01

    feedback on the OT results before a milestone review and then delivering the OT report, with surprises, virtually at the review. Test Realism There...of the R3D/100 Chip Set and Simulation Heritage. MLRS WE’RE IN THE ARMY NOW TE 14(1 Video, 15 Mins) Cinematics - LTV Aerospace & Defense

  19. [Interdisciplinary teamwork in the OR: Identification and measurement of teamwork in the operating room].

    Science.gov (United States)

    Passauer-Baierl, Stefanie; Baschnegger, Heiko; Bruns, Christiane; Weigl, Matthias

    2014-01-01

    Effective teamwork is one of the essentials in conducting successful and safe surgical procedures in the operating theatre (OT). The present paper aims to provide a selective review of various approaches describing effective interdisciplinary teamwork in the OT. Furthermore, it covers observational methods to assess OT teamwork with particular focus on Germany. Our definition of successful surgical teamwork is based on an already established classification system considering five criteria for effective and safe OT teams: coordination, communication, cooperation, leadership, and team monitoring. Well-defined and reliable measures are necessary to examine the quality of OT teamwork. Those methods should entail the special characteristics of the OT team. They should include all phases of the surgical procedure and incorporate all the professions involved (surgeons, surgical nurses, and anaesthetic staff). We conclude that research into methods for the assessment of OTs in Germany needs to be undertaken as a prerequisite to investigating the relationship between OT teamwork and its effects on patient safety and surgical quality. Copyright © 2013. Published by Elsevier GmbH.

  20. The Role of Occupational Therapists and Physical Therapists in Elementary School System Early Intervening Services and Response to Intervention: A Case Report

    Science.gov (United States)

    Reeder, Deborah L.; Arnold, Sandra H.; Jeffries, Lynn M.; McEwen, Irene R.

    2011-01-01

    The Individuals with Disabilities Improvement Act and No Child Left Behind Act broadened the roles of occupational therapists (OTs) and physical therapists (PTs) to include therapist participation in early intervening services including response to intervention (RTI). This case report describes one school district's inclusion of OT and PT in the…

  1. Occupational Therapy ’s Role in an Interprofessional Student-Run Free Clinic: Challenges and Opportunities Identified

    Directory of Open Access Journals (Sweden)

    Oaklee Rogers

    2017-07-01

    Full Text Available Student-run free clinics (SRFCs provide services to underserved populations while enhancing student education. Occupational therapy (OT participation in integrated care SRFCs is an emerging area of practice and enhances the interprofessional model necessary for holistic patient care. The Student Health Outreach for Wellness (SHOW organization, located in Phoenix, Arizona, is a SRFC comprised of three state universities that incorporates nine different health professional programs to deliver interprofessional care, including OT. The SHOW clinic provides direct care services where student volunteers practice clinical and interprofessional skills under the guidance of licensed health care providers. OT preceptors and students participate in team-based assessment and care delivery to practice their discipline-specific treatment knowledge of upper-extremity impairments, musculoskeletal pain, medication management, fall prevention, and behavioral health issues, among many others. OT integration into the clinic provides students and preceptors an opportunity to build a unique skill set in interprofessional care, educate other disciplines about OT, and become emerging leaders in the field. Challenges for OT involvement in this SRFC include recruitment and sustainability of volunteers and lack of knowledge and understanding about the role of OT on an interprofessional team. Further research is needed to identify additional benefits of OT services in SFRCs.

  2. 12 CFR 557.13 - What State laws affecting deposits are not preempted?

    Science.gov (United States)

    2010-01-01

    ... purposes of § 557.11: (1) Contract and commercial law; (2) Tort law; and (3) Criminal law. (b) The OTS will not preempt any other state law if the OTS, upon review, finds that the law: (1) Furthers a vital... 12 Banks and Banking 5 2010-01-01 2010-01-01 false What State laws affecting deposits are not...

  3. Minimalism and Optimality Theory

    NARCIS (Netherlands)

    Broekhuis, H.; Woolford, E.; den Dikken, M.

    2013-01-01

    This article discusses the relation between the minimalist program (MP) and optimality theory (OT) and will show that, contrary to popular belief, MP and OT are not inherently incompatible or competing frameworks/theories. Instead, we will show (i) that the two can well be seen as complementary

  4. Intranasal Oxytocin Normalizes Amygdala Functional Connectivity in Posttraumatic Stress Disorder.

    Science.gov (United States)

    Koch, Saskia B J; van Zuiden, Mirjam; Nawijn, Laura; Frijling, Jessie L; Veltman, Dick J; Olff, Miranda

    2016-07-01

    The neuropeptide oxytocin (OT) has been suggested as a promising pharmacological agent for medication-enhanced psychotherapy in posttraumatic stress disorder (PTSD) because of its anxiolytic and prosocial properties. We therefore investigated the behavioral and neurobiological effects of a single intranasal OT administration (40 IU) in PTSD patients. We conducted a randomized, placebo-controlled, cross-over resting-state fMRI study in male and female police officers with (n=37, 21 males) and without PTSD (n=40, 20 males). We investigated OT administration effects on subjective anxiety and functional connectivity of basolateral (BLA) and centromedial (CeM) amygdala subregions with prefrontal and salience processing areas. In PTSD patients, OT administration resulted in decreased subjective anxiety and nervousness. Under placebo, male PTSD patients showed diminished right CeM to left ventromedial prefrontal cortex (vmPFC) connectivity compared with male trauma-exposed controls, which was reinstated after OT administration. Additionally, female PTSD patients showed enhanced right BLA to bilateral dorsal anterior cingulate cortex (dACC) connectivity compared with female trauma-exposed controls, which was dampened after OT administration. Although caution is warranted, our findings tentatively suggest that OT has the potential to diminish anxiety and fear expression of the amygdala in PTSD, either via increased control of the vmPFC over the CeM (males) or via decreased salience processing of the dACC and BLA (females). Our findings add to accumulating evidence that OT administration could potentially enhance treatment response in PTSD.

  5. Neonatal oxytocin manipulations have long-lasting, sexually dimorphic effects on vasopressin receptors

    OpenAIRE

    Bales, KL; Plotsky, PM; Young, LJ; Lim, MM; Grotte, N; Ferrer, E; Carter, CS

    2007-01-01

    Developmental exposure to oxytocin (OT) or oxytocin antagonists (OTAs) has been shown to cause long-lasting and often sexually dimorphic effects on social behaviors in prairie voles (Microtus ochrogaster). Because regulation of social behavior in monogamous mammals involves central receptors for OT, arginine vasopressin (AVP), and dopamine, we examined the hypothesis that the lon...

  6. The effect of operating lamps on the protected area of a unidirectional down flow (UDF) system

    NARCIS (Netherlands)

    Traversari, A.A.L.; Bottenheft, C.; Louman, R.; Heumen, S.P.M. van; Böggeman, J.

    2016-01-01

    Background: Operating lamps are often seen as the most disruptive factors within the protective area in the operating theater (OT). The effect of the operation lamps (with different shapes) should be demonstrated in an OT by trial, since research on the effects of the lamps is still limited.

  7. Community stakeholders’ perspectives on the role of occupational therapy in primary healthcare: Implications for practice

    Directory of Open Access Journals (Sweden)

    Deshini Naidoo

    2017-02-01

    Conclusion: The understanding of the intervention required by OT in PHC was enhanced through obtaining the views of various stakeholders’ on the role. This study highlighted the gaps in community-based services that OTs should offer in this context.

  8. Endolaryngeal Surgery of Bilateral Vocal Cord Abductor Paralysis

    African Journals Online (AJOL)

    1971-12-04

    Dec 4, 1971 ... S. L. SELLARS, M.A., F.R.C.S., Senior Lecturer, Department ot Otolaryngology, Medical School,. University ot Cape Town. SUMMARY. The treatment of bilateral recurrent laryngeal nerve palsy is discussed and the method of endolaryngeal arytenoidectomy and cordopexy is described in detail. Two.

  9. System Architecture for Anti-Ship Ballistic Missile Defense (ASBMD)

    Science.gov (United States)

    2009-12-01

    Execute Search Search Function Link/SATCOM Info Operator Input Output Search Results D etect Function O rganic R esources Avail Receive Remote...Queue O rganic R esources N ot Avail Track Function D etect Function O rganic R esources Avail O rganic R esources N ot Avail Appendix C 153 4.1.2

  10. Molecular evolution of the neurohypophysial hormone precursors in mammals: Comparative genomics reveals novel mammalian oxytocin and vasopressin analogues.

    Science.gov (United States)

    Wallis, Michael

    2012-11-01

    Among vertebrates the neurohypophysial hormones show considerable variation. However, in eutherian mammals they have been considered rather conserved, with arginine vasopressin (AVP) and oxytocin (OT) in all species except pig and some relatives, where lysine vasopressin replaces AVP. The availability of genomic data for a wide range of mammals makes it possible to assess whether these peptides and their precursors may be more variable in Eutheria than previously suspected. A survey of these data confirms that AVP and OT occur in most eutherians, but with exceptions. In a New-World monkey (marmoset, Callithrix jacchus) and in tree shrew (Tupaia belangeri), Pro(8)OT replaces OT, confirming a recent report for these species. In armadillo (Dasypus novemcinctus) Leu(3)OT replaces OT, while in tenrec (Echinops telfairi) Thr(4)AVP replaces AVP. In these two species there is also evidence for additional genes/pseudogenes, encoding much-modified forms of AVP, but in most other eutherian species there is no evidence for additional neurohypophysial hormone genes. Evolutionary analysis shows that sequences of eutherian neurohypophysial hormone precursors are generally strongly conserved, particularly those regions encoding active peptide and neurophysin. The close association between OT and VP genes has led to frequent gene conversion of sequences encoding neurophysins. A monotreme, platypus (Ornithorhynchus anatinus) has genes for OT and AVP, organized tail-to-tail as in eutherians, but in marsupials 3-4 genes are present for neurohypophysial hormones, organized tail-to-head as in lower vertebrates. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Advancing Ergonomic Expertise in Occupational Therapists: Using an Online Course to Facilitate Knowledge Acquisition and Application of Ergonomics in Daily Practice

    Science.gov (United States)

    Finch, Denise E.

    2012-01-01

    Health promotion, prevention of disease and disability, and enhancing participation in meaningful life activities are areas that occupational therapists (OT) can contribute to at the individual, organizational and population levels (AOTA, 2008; Scaffa, Van Slyke & Brownson, 2008). OTs that are skilled in ergonomic assessment and evidence-based…

  12. Orthoptic Treatment of Convergence Insufficiency in Parkinson's Disease: A Case Series.

    Science.gov (United States)

    Kergoat, Hélène; Law, Caroline; Chriqui, Estefania; Kergoat, Marie-Jeanne; Leclerc, Bernard-Simon; Panisset, Michel; Postuma, Ronald; Irving, Elizabeth L

    2017-01-01

    Introduction: This study reports a case series of orthoptic treatment (OT) for convergence insufficiency (CI) in individuals with Parkinson's disease (PD). Method: We are reporting two cases of individuals with PD who completed OT for CI. Both had a confirmed diagnosis of CI, accompanied by CI-type symptomatology. They each underwent an OT program consisting of three office-based visits and 8 weeks of home-based exercises. Treatment outcome was based on the changes measured pre- versus post-OT on the near point of convergence, positive fusional vergences, and symptomatology score. Results: The two participants successfully completed therapy, gained ability to converge, had fewer symptoms, and were satisfied with the OT-induced changes they felt in their day-to-day lives. Conclusion: This case series show that OT for CI in PD is possible. Further research is required as these results demonstrate that OT has the potential to improve symptomatic CI in these patients. In the meantime, the positive results obtained in these two cases should encourage clinicians to consider OT (a therapy with no/minimal risk) for CI in patients with PD whose quality of life is affected by this binocular dysfunction.

  13. Evaluation and Opportunities in Overtraining Approaches

    Science.gov (United States)

    Roose, Jolanda; de Vries, Wouter R.; Schmikli, Sandor L.; Backx, Frank J. G.; van Doornen, Lorenz J. P.

    2009-01-01

    Overtraining (OT) as a sports phenomenon can be caused by stressors on various levels (physical, emotional, psychological, and social) and evokes responses on these levels. This study evaluated research and new opportunities in the field of OT by introducing an integrated multidisciplinary approach, based on the single and multistressors approach.…

  14. Determination of ocular torsion by means of automatic pattern recognition

    NARCIS (Netherlands)

    Groen, E.L.; Bos, J.E.; Nacken, P.F.M.; Graaf, B. de

    1996-01-01

    A new, automatic method for determination of human ocular torsion (OT) was devel-oped based on the tracking of iris patterns in digitized video images. Instead of quanti-fying OT by means of cross-correlation of circular iris samples, a procedure commonly applied, this new method automatically

  15. Determination of ocular torsion by means of automatic pattern recognition

    NARCIS (Netherlands)

    Groen, Eric; Bos, Jelte E.; Nacken, Peter F M; De Graaf, Bernd

    A new, automatic method for determination of human ocular torsion (OT) was developed based on the tracking of iris patterns in digitized video images. Instead of quantifying OT by means of cross-correlation of circular iris samples, a procedure commonly applied, this new method automatically selects

  16. Working in the Methodological "Outfield": The Case of Bourdieu and Occupational Therapy

    Science.gov (United States)

    Watson, Jo; Grenfell, Michael

    2016-01-01

    The article reports on a study of methodological innovation involving occupational therapy (OT) students in higher education (HE). It is based on an original project which examined the experiences and outcomes of non-traditional entrants to pre-registration OT education. A feature of the original project was the application of the epistemological…

  17. Oxytocin Signaling in Basolateral and Central Amygdala Nuclei Differentially Regulates the Acquisition, Expression, and Extinction of Context-Conditioned Fear in Rats

    Science.gov (United States)

    Campbell-Smith, Emma J.; Holmes, Nathan M.; Lingawi, Nura W.; Panayi, Marios C.; Westbrook, R. Frederick

    2015-01-01

    The present study investigated how oxytocin (OT) signaling in the central (CeA) and basolateral (BLA) amygdala affects acquisition, expression, and extinction of context-conditioned fear (freezing) in rats. In the first set of experiments, acquisition of fear to a shocked context was impaired by a preconditioning infusion of synthetic OT into the…

  18. Discrepant perceptions of communication, teamwork and situation awareness among surgical team members

    NARCIS (Netherlands)

    Wauben, L.S.G.L.; Dekker-van Doorn, C.M.; Van Wijngaarden, J.H.D.; Goossens, R.H.M.; Huijsman, R.; Klein, J.; Lange, J.F.

    2011-01-01

    Objective To assess surgical team members’ differences in perception of non-technical skills. Design Questionnaire design. Setting Operating theatres (OTs) at one university hospital, three teaching hospitals and one general hospital in the Netherlands. Participants Sixty-six surgeons, 97 OT nurses,

  19. Preparation of open tubular capillary columns by in situ ring-opening polymerization and their applications in cLC-MS/MS analysis of tryptic digest.

    Science.gov (United States)

    Wang, Hongwei; Yao, Yating; Li, Ya; Ma, Shujuan; Peng, Xiaojun; Ou, Junjie; Ye, Mingliang

    2017-08-01

    An open tubular (OT) column (25 μm i.d.) was prepared by in situ ring-opening polymerization of octaglycidyldimethylsilyl polyhedral oligomeric silsesquioxanes (POSS-epoxy) with 4-aminophenyl disulfide (APDS) in a binary porogenic system of ethanol/H 2 O. It was found that porogenic composition played an important role in the formation of OT stationary phases. The ratio of ethanol/H 2 O at 6/1 (v/v) would lead to the fabrication of hybrid monoliths, while the ratio of ethanol/H 2 O at 13/1 (v/v) would result in the synthesis of OT phases. In addition, the effects of precursor content and reaction duration on the thickness of OT stationary phases were investigated. Either lower precursor content or shorter reaction duration would produce thinner layer of OT column. The repeatability of OT columns was evaluated through relative standard deviation (RSD%) with benzene as the analyte. The run-to-run, column-to-column and batch-to-batch repeatabilities were 1.7%, 4.8% and 5.6%, respectively, exhibiting satisfactory repeatability of the OT column. Then tryptic digest of mouse liver proteins was used to evaluate the performance of the resulting OT columns (25 μm i.d. × 2.5 m in length) by cLC-MS/MS analysis, demonstrating their potential in proteome analysis. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. 76 FR 6191 - Proposed Agency Information Collection Activities; Comment Request-Thrift Financial Report

    Science.gov (United States)

    2011-02-03

    ...' association concerning the definition of core deposits, which was not an element of the OTS's October 5, 2010.... generally accepted accounting principles (GAAP). The OTS received comments from a bankers' association on... breakdowns by loan category, until the FASB finalizes proposed clarifications to its standards for accounting...