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Sample records for edyta sienkiewicz grzegorz

  1. A diagnosis of strangeness. Brzozowski’s Anti-Sienkiewicz campaign as a dispute about Polish identity

    Directory of Open Access Journals (Sweden)

    Krzysztof Fiołek

    2016-03-01

    Full Text Available This essay discusses the Anti-Sienkiewicz campaign briefly. The affair happened in 1903 in the Warsaw weekly magazine “Głos”, but was written up in many Polish newspapers. Stanisław Brzozowski (1878-1911, the beginning publicist, literary critic and novelist spoke against Sienkiewicz’s famous works. Sienkiewicz’s main novels have been criticised for their conservatism and lack of social progressiveness, although they display great narrative power and contain vivid characterisations in a style full of imagery. The lack of national independence created greater reverence towards national history in 19th century Polish literature. Sienkiewicz felt a close bond with the Polish nobility. Brzozowski tried to put his own philosophy of culture and his concept of the “philosophy of labour” into practice. He spoke as am exponent of Polish modernism and socialism.

  2. Professor Andrzej Budzanowski, Director General, Henryk Niewodniczanski Institute of Nuclear Physics (HNINP) Poland. Dr. Grzegorz Polok, Deputy Director

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Andrzej Budzanowski, Director-General of the Cracow Institute of Nuclear Physics (HNINP) and Lyn Evans, LHC Project Leader, signing the collaboration agreement. In the background, from leftto right : Grzegorz Polok, Deputy Director-General of the Cracow Institute of Nuclear Physics, Blazej Skoczen, in charge of the LHC cryomagnet interconnections, Claude Détraz, Director for Fixed Target and Future Programmes, Alain Poncet, AT/CRI Group Leader.

  3. Signature of a Collaboration Agreement between The Andrzej Soltan Institute for Nuclear Studies (IPJ) and CERN, by Prof. Grzegorz Wrochna, Director and CERN Director-General, concerning Collaboration in the LHC upgrade.

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    Maximilien Brice

    2011-01-01

    Signature of a Collaboration Agreement between The Andrzej Soltan Institute for Nuclear Studies (IPJ) and CERN, by Prof. Grzegorz Wrochna, Director and CERN Director-General, concerning Collaboration in the LHC upgrade.

  4. Book Review: Górny, Grzegorz, Janusz Rosikoń and Stan Kacsprzak, Guadalupe Mysteries: Deciphering the Code, San Francisco: Ignatius Press, 2016

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    Daniel Ymbong

    2017-11-01

    Full Text Available Author-photographer duo Grzegorz Górny and Rosikoń Janusz in Guadalupe Mysteries: Deciphering the Code, thoroughly examine the Guadalupe tilma (cloak in terms of its chronology, and political relevance in national identity, and religion. The book also examines the complex iconographies present in image and name, recently discovered scientific and mathematical phenomena relating to the tilma and the cultural fashion aspect of tilmas in general.

  5. After Pasolini’s Teorema: Notes on the Theatre of Grzegorz Jarzyna and Mikołaj Mikołajczyk

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    Armando Rotondi

    2014-06-01

    Full Text Available The following contribution aims to analyse two adaptations of Pier Paolo Pasolini’s Teorema, written and directed by, respectively, Grzegorz Jarzyna and Mikołaj Mikołajczyk. In the first, T.E.O.R.E.M.A.T., Jarzyna works both on Pasolini’s novel and film, creating a performance composed of the distorted use of the voice, silent dialogues and proximity games, producing a highly conceptual effect. In his Wszystko jutro, czyli lalki wybawione, Mikołajczyk, on the other hand, recreates Pasolini’s story as a choreographed drama, which examines the dilemmas posed by the Italian author.

  6. “The Many Languages of the Avant-Garde”: In conversation with Grzegorz Bral of Teatr Pieśń Kozła (Song of the Goat Theatre

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    Sakowska Aleksandra

    2014-12-01

    Full Text Available How to theorise and review avant-garde Shakespeare? Which theoretical paradigms should be applied when Shakespearean productions are multicultural and yet come from a specific locale? These and other many questions interrogating the language of performance in global avant-garde Shakespeare productions are put forward to Grzegorz Bral, the director of the Song of the Goat ensemble in the context of their evolving performance of Macbeth (2006/2008 and their Songs of Lear (2012.

  7. Playing with Gombrowicz / Grzegorz Janikowski

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    Janikowski, Grzegorz

    2004-01-01

    Ka E. Nüganeni lavastatud W. Gombrowiczi "Laulatusest" Toruni teatri Teatr im. Horzycy esituses 9. rahvusvahelisel festivalil "Theatre Confrontations" Lublinis (6.-10. okt. 2004). Paralleeltekst prantsuse keeles

  8. Profile of infliximab in the treatment of pediatric Crohn’s disease

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    Kierus J

    2015-06-01

    Full Text Available Jaroslaw Kierkus,1 Edyta Szymanska,2 Grzegorz Oracz,1 Anna Wiernicka,1 Maciej Dadalski1 1Department of Gastroenterology, Hepatology, Feeding Disorders and Pediatrics, 2Department of Pediatrics, Nutrition and Metabolic Disorders, The Children’s Memorial Health Institute, Warsaw, Poland Abstract: In recent years, a novel biologic therapy with monoclonal antibodies against tumor necrosis factor-alpha has revolutionized the treatment of Crohn’s disease. Infliximab, the first biologic agent, has been demonstrated to considerably improve both clinical and endoscopic outcomes. In view of the growing popularity of infliximab in the management of Crohn’s disease, we review the profile of the agent in the treatment of this disease in a pediatric setting. Keywords: infliximab, Crohn’s disease, children, biologic therapy, anti-TNF-agents

  9. The Spanish mysticism in paintings by artists from the Fine Arts Academy in Krakow at the turn of the 21st century

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    Adam Organisty

    2016-12-01

    Full Text Available During the last two decades the works of teachers from the Painting Department of the Academy of Fine Arts in Krakow: Grzegorz Bednarski, Katarzyna Makieła-Organisty, Janusz Matuszewski, Mirosław Sikorski, Edyta Sobieraj, Zbigniew Sprycha or Wojciech Szybist reveal traces of inspiration by the Spanish Golden Age. In this respect, paintings by Krakow artists stand out against other works of contemporary art both in Poland and globally. Their art should be discussed in the context of early modern meditatio mortis and tenebristic „baroqueism”, to which the artists themselves readily admit. The point of departure (frequently referred to as homage are mystic visions, portraits by El Greco, Francisco de Zurbarán’s bodegóns or eschatological „death hieroglyphics” by Juan de Valdés Léal. References to works by the Iberian masters are accompanied by links to Carmelite writings or Jesuit mystics. Formal and ideological analysis also allows us to ask a question of the possibility of presenting the „mystic theology” described by St. Theresa of the Infant Jesus, St. John of the Cross or St. Ignatius of Loyola in contemporary religious paintings.

  10. Samobójstwo estetyczne. Na marginesie Quo vadis Henryka Sienkiewicza (ESTHETICAL SUICIDE. ON THE MARGIN OF 'QUO VADIS?' BY H. SIENKIEWICZ

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    Ireneusz Ziemiński

    2006-12-01

    Full Text Available The article presents the Petronius' suicide (as a character of 'Quo vadis?' in the context of ancient and Christian concept of death and dying. Petronius' death arranged as a piece of art (to realize the idea of beauty is an icon of the ancient Rome's passing culture. It is a theatre of death and that is why it can not be the pattern to follow or any resolving of human existential mortality problem. Better attitude to death is Eunice's suicide committed for love as absolute value. Petronius' conduct and way of living was dependent on philosophy of Stoics, Epicureans, and first of all Skeptics. In this context we can see weakness of ancient philosophy as 'meditatio mortis'. Esthetical suicide as a final act of life is only human and it does not point to any eternal value. On the contrary, the death of the Christian martyrs reduced to bloody performance on the arena, points to transcendent aspect of human life and dying. According to Petronius, the way of dying is the best value criterion of any religious or philosophical doctrine and you can die with dignity even if you do not believe in Christ or eternal life. He tried to demonstrate the best values of Rome but his theatric death was rather empty gesture than the evidence of death's majesty. Christians' martyr death for faith seems more authentic than Petronius' esthetical suicide.

  11. Recognition and enforcement of foreign court judgments in Poland / Jacek Gołaczyński, Grzegorz Karaś

    Index Scriptorium Estoniae

    Gołaczyński, Jacek

    2010-01-01

    Euroopa Liidu Nõukogu (EÜ) määrusest nr. 44/2001 (22. detsember 2000, kohtualluvuse ja kohtuotsuste täitmise kohta tsiviil- ja kaubandusasjades) ja selle täitmisest Poolas, keeldumise õiguslikest alustest

  12. Välisriigi kohtulahendite tunnustamine ja täitmine Poolas / Jacek Gołaczyński, Grzegorz Karaś

    Index Scriptorium Estoniae

    Gołaczyński, Jacek

    2010-01-01

    Euroopa Liidu Nõukogu (EÜ) määrusest nr. 44/2001 (22. detsember 2000, kohtualluvuse ja kohtuotsuste täitmise kohta tsiviil- ja kaubandusasjades) ja selle täitmisest Poolas, keeldumise õiguslikest alustest

  13. Ojczyzna czy rodzina? Dylemat księcia Bogusława Radziwiłła (1620–1669)

    OpenAIRE

    Wijaczka, Jacek

    2013-01-01

    Thanks to the novel ‘The Deluge’ written by Henryk Sienkiewicz, first published as a book in 1886, the Master of the Horse – Lithuanian Duke Bogusław Radziwiłł was perceived as a traitor during the Swedish invasion of Poland in the years 1655–1660. The writer presented him in a manner which differed significantly from the image of a typical nobleman – szlachcic – of the Polish-Lithuanian Commonwealth. Moreover, according to Sienkiewicz, Bogusław preferred speaking French or German instead of ...

  14. Grzegorz Dąbrowski, "Prosta etnografia Wileńszczyzny", Wydział Nauk Historycznych i Pedagogicznych Uniwersytetu Wrocławskiego. Katedra Etnologii i Antropologii Kulturowej, Wrocław 2013, ss. 313. „Wileńszczyzna. Przedmioty – opowieści – refleksje” red. Piotr Oleksy, Mateusz Sikora, Epigram, Bydgoszcz 2012, ss. 185

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    Michał Głuszkowski

    2014-12-01

    Full Text Available The review concerns two books devoed to the sociocultural, historical and lingusitic situation of Vilnius region (Lithuania. The author compares G. Dąbrowski's 'simple' ethnography and the practical application of his theories in the volume "Wileńszczyzna. Przedmioty – opowieści – refleksje".

  15. Tavatu kriis / Vlady Kellik

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    Kellik, Vlady

    2010-01-01

    Autor tutvustab Varssavi Transformatsiooni, Integratsiooni ja Globaliseerumise Uurimiskeskuse (TIGER) direktori Grzegorz Kolodko poolt Moskvas Rahandusakadeemia audoktoriks promoveerimise puhul peetud loengut. Teadlase hinnangul osutus majandusbuum neoliberalismi nurisünnitiseks

  16. Quo Vadis on Film (1912, 1925, 1951, 1985, 2001, The many Faces of Antiquity

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    Ewa Skwara

    2013-12-01

    Full Text Available The Polish novel Quo vadis by Henryk Sienkiewicz was adapted into film five times. Every adaptation was filmed in special circumstances, accompanied by different political situations and each time for a different, specific audience. The comparison and detailed analysis of all versions will bring to light, how and for what purpose has antiquity been translated onto the silver screen. The paper will focus especially on the three adaptations – the American (1951, the Italian (1985 and the Polish one (2001.

  17. Gregory in Constantinople as a Responsaus of Pope Pelagius II

    OpenAIRE

    Wolińska, Teresa

    1996-01-01

    Niniejszy artykuł prezentuje działalność Grzegorza, późniejszego papieża, jako nuncjusza papieskiego w Konstantynopolu. Czas jego misji przypada na lata ok. 579-584/5. Grzegorz reprezentował na dworze cesarskim interesy papieża Pelagiusza II (579-590). Wybrany na tak wysokie stanowisko z racji swego doświadczenia w służbie publicznej i walorów duchowych Grzegorz dobrze spełniał powierzone sobie obowiązki. Utrzymywał szerokie kontakty nie tylko z cesarzami i członkami ich rodzin...

  18. [leksikon-artikler : 51 stk. cf. abstract

    DEFF Research Database (Denmark)

    Walczak-Andersen, Ewa

    2007-01-01

    . Jarzyna, Grzegorz . Jaunimo teatras . Jugoslavien . Juliusza Slowackigo, Teatr im. . Kantor, Tadeusz . Katona, József . Kott, Jan . Krasinski, Zygmunt . Krétakör Színház . Kroatien . Letland . Litauen . Lupa, Krystian . Madách, Imre . Mickiewicz, Adam . Montenegro . Národní divadlo . Narodowy, Teatr...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 40; Issue 3. A rapidly progressing, deadly disease of Actias selene (Indianmoonmoth) larvae associated with a mixed bacterial and baculoviral infection. Marta A Skowron Beata Guzow-Krzemińska Sylwia Barańska Paulina Jędrak Grzegorz Węgrzyn. Articles Volume 40 ...

  20. A rapidly progressing, deadly disease ofActias selene (Indian moon ...

    Indian Academy of Sciences (India)

    Marta A Skowron1 2 Beata Guzow-Krzemińska1 Sylwia Barańska1 Paulina Jędrak1 Grzegorz Węgrzyn1. Department of Molecular Biology, Division of Biology, University of Gdansk, Wita Stwosza 59, 80-308, Gdansk, Poland; Department of Molecular Biotechnology, Institute for Environmental and Human Health Protection, ...

  1. Annual Report 2008

    International Nuclear Information System (INIS)

    Keeley, N.; Skalski, J.

    2009-01-01

    The ''Annual Report 2008'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2008. Report consists of two parts. First one consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given

  2. Response to “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review” paper

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    Muc-Wierzgoń M

    2015-05-01

    Full Text Available Malgorzata Muc-Wierzgoń, Teresa Kokot, Ewa Nowakowska-Zajdel, Adam Błażelonis, Edyta Fatyga Department of Internal Medicine, Silesian Medical University, Bytom, PolandDear editorGil-Montoya et al has recently published an interesting article in Clinical Interventions in Aging entitled: “Oral health in the elderly patient and its impact on general well-being: a nonsystematic review”.1 Authors presented a non-systematic review of the published data regarding the oral health status of the elderly and its main repercussions, including its impact on general health and nutrition.View original paper by Gil-Montoya and colleagues.

  3. Assess the knowledge level of POZ patients on the diagnosis and treatment of type 2 diabetes

    OpenAIRE

    Żebrowska, Małgorzata; Medak, Edyta; Pachuta, Małgorzata; Brodowicz-Król, Magdalena

    2017-01-01

    Żebrowska Małgorzata, Medak Edyta, Pachuta Małgorzata, Brodowicz-Król Magdalena. Assess the knowledge level of POZ patients on the diagnosis and treatment of type 2 diabetes. Journal of Education, Health and Sport. 2017;7(7):338-356. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.831845 http://ojs.ukw.edu.pl/index.php/johs/article/view/4632 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B ...

  4. Long-term administration of high doses of transdermal buprenorphine in cancer patients with severe neuropathic pain

    OpenAIRE

    Leppert, Wojciech; Kowalski,Grzegorz

    2015-01-01

    Wojciech Leppert, Grzegorz Kowalski Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland Background: Buprenorphine is often administered by the transdermal route (transdermal buprenorphine [TB]) in cancer patients with severe neuropathic pain. However, high doses of TB of 140 µg/h are rarely used.Patients and methods: Three cancer patients with severe neuropathic Numeric Rating Scale (NRS) pain scores of 8–10 who were success...

  5. Long-term administration of high doses of transdermal buprenorphine in cancer patients with severe neuropathic pain

    OpenAIRE

    Leppert W; Kowalski G

    2015-01-01

    Wojciech Leppert, Grzegorz Kowalski Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland Background: Buprenorphine is often administered by the transdermal route (transdermal buprenorphine [TB]) in cancer patients with severe neuropathic pain. However, high doses of TB of 140 µg/h are rarely used.Patients and methods: Three cancer patients with severe neuropathic Numeric Rating Scale (NRS) pain scores of 8–10 who were successfully tr...

  6. Annual Report 2007

    International Nuclear Information System (INIS)

    Chmielewska, D.; Infeld, E.; Zupranski, P.

    2008-01-01

    The ''Annual Report 2007'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2007. Report consists of two parts. First one consist of of general information about location, management, scientific council, personnel, financial support and conferences while the second one describes the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to all report written by Director of the Institute prof. Grzegorz Wrochna is also given

  7. Annual Report 2006

    International Nuclear Information System (INIS)

    Chmielewska, D.; Infeld, E.; Zupranski, P.

    2007-06-01

    The ''Annual Report 2006'' describes activities of Andrzej Soltan Institute for Nuclear Studies in 2006. Report consists in general two parts. First consists of general information about location, management, scientific council, personnel, financial support and conferences while the second one the scientific activity of Institute. This part is divided into subsections which present progress in research of the Institut Departments and Establishments. A Foreword to report written by Director of the Institute Grzegorz Wrochna is also given

  8. Historia de un mito ultramontano: Quo Vadis? y la cuestión romana

    OpenAIRE

    Fernández-Mayoralas Palomeque, Juan

    2016-01-01

    El objetivo de esta tesis es explicar la génesis y el desarrollo de un mito historiográfico que hemos llamado mito ultramontano de la Roma de Nerón, y que cristalizó en un libro publicado a finales del siglo XIX, Quo vadis?, de Henryk Sienkiewicz. Gracias al éxito del libro y de las adaptaciones cinematográficas, esta obra contribuyó decisivamente a cambiar la percepción de la Antigüedad (y en especial de las relaciones entre el Imperio romano y el primitivo cristianismo) más allá de su ámb...

  9. “Wildness” as a metaphor for self-definition of the colonised subject in the Positivist period in Poland

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    Anna Kołos

    2011-06-01

    Full Text Available This article discusses the question of the Polish nation's self-definition in the Positivist period both in belles-lettres and in journalism, which were dependent to a great extent on the colonial discourse. It is argued that crucial metaphors of “wildness,” “savageness” or “backwardness” stem from orientalising labels created by the colonisers. Examination of this issue requires some basic introduction to historical and anthropological ideas which date back to the Age of Enlightenment. The aim of this paper is to shed light – by analysing literature examples such as Ludwik Powidaj, Cyprian Kamil Norwid, Maria Konopnicka, Eliza Orzeszkowa and Henryk Sienkiewicz – on the so called “colonial trauma” that has condemned the Polish image to resentful ideology. Furthermore, the paper will provide arguments in favour of subscribing to the postcolonial studies in Central and Eastern Europe.

  10. Response to vitamin D and depression in geriatric primary care patients

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    Muc-Wierzgoń M

    2013-07-01

    Full Text Available Malgorzata Muc-Wierzgon, Ewa Nowakowska-Zajdel, Katarzyna Klakla, Sylwia Dziegielewska-Gesiak, Edyta Fatyga, Teresa Kokot Department of Internal Medicine, Silesian Medical University, Katowice, PolandLapid et al recently published an interesting article in Clinical Interventions in Aging entitled: "Vitamin D and depression in geriatric primary care patients".1 Their conclusion that "lower vitamin D levels were associated with depression" was based on a study that analyzed the patients in primary care internal medicine "who had at least one total serum 25-hydroxyvitamin D [25(OHD] level from 2004–2008. For those with multiple serum 25(OHD measurements, authors used the index of first measurements".1View original paper by Lapid and colleagues.

  11. Frakcja lipidowa i białkowa nasion konopi siewnych (C. sativa L.) oraz jej korzystny wpływ na zdrowie człowieka = Lipid and protein fraction of hemp seed (C. sativa L.) and its beneficial influence on human health

    OpenAIRE

    Dąbrowski, Grzegorz; Skrajda, Marta

    2016-01-01

    Dąbrowski Grzegorz, Skrajda Marta. Frakcja lipidowa i białkowa nasion konopi siewnych (C. sativa L.) oraz jej korzystny wpływ na zdrowie człowieka = Lipid and protein fraction of hemp seed (C. sativa L.) and its beneficial influence on human health. Journal of Education, Health and Sport. 2016;6(9):357-366. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.62002 http://ojs.ukw.edu.pl/index.php/johs/article/view/3839 The journal has had 7 points in Ministry of Sci...

  12. Atomic and Molecular Data and their Applications★

    Science.gov (United States)

    Drake, Gordon W. F.; Yoon, Jung-Sik; Kato, Daiji; Karwasz, Grzegorz

    2018-03-01

    This topical issue on Atomic and molecular data and their applications was motivated by the 10th International Conference on Atomic and Molecular Data (ICAMDATA 2016), which was held from September 26 to 29, 2016 in Gunsan, Republic of Korea. The topics of this issue reflect those of the conference program. The scientific papers in the topical issue cover the fields of atomic and molecular structure, radiative transitions, scattering processes, data base development, and the applications of atomic and molecular data to plasma modeling. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, and Grzegorz Karwasz.

  13. The real Fatou conjecture (AM-144)

    CERN Document Server

    Graczyk, Jacek

    2014-01-01

    In 1920, Pierre Fatou expressed the conjecture that--except for special cases--all critical points of a rational map of the Riemann sphere tend to periodic orbits under iteration. This conjecture remains the main open problem in the dynamics of iterated maps. For the logistic family x- ax(1-x), it can be interpreted to mean that for a dense set of parameters ""a,"" an attracting periodic orbit exists. The same question appears naturally in science, where the logistic family is used to construct models in physics, ecology, and economics. In this book, Jacek Graczyk and Grzegorz Swiatek provi

  14. Software Switching for Data Acquisition

    CERN Multimedia

    CERN. Geneva; Malone, David

    2016-01-01

    In this talk we discuss the feasibility of replacing telecom-class routers with a topology of commodity servers acting as software switches in data acquisition. We extend the popular software switch, Open vSwitch, with a dedicated, throughput-oriented buffering mechanism. We compare the performance under heavy many-to-one congestion to typical Ethernet switches and evaluate the scalability when building larger topologies, exploiting the integration with software-defined networking technologies. Please note that David Malone will speak on behalf of Grzegorz Jereczek.

  15. Cannabinoids from Cannabis sp.: mechanism of their activity and potential health benefits in human body

    OpenAIRE

    Dąbrowski, Grzegorz; Skrajda, Marta

    2017-01-01

    Dąbrowski Grzegorz, Skrajda Marta, Cannabinoids from Cannabis sp.: mechanism of their activity and potential health benefits in human body. Journal of Education, Health and Sport. 2017;7(8):936-945. eISSN 2391-8306. DOI http://dx.doi.org/10.5281/zenodo.995625 http://ojs.ukw.edu.pl/index.php/johs/article/view/4876 The journal has had 7 points in Ministry of Science and Higher Education parametric evaluation. Part B item 1223 (26.01.2017). 1223 Jo...

  16. The influence of intrauterine exposure to immunosuppressive treatment on changes in the immune system in juvenile Wistar rats

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    Kabat-Koperska J

    2016-07-01

    Full Text Available Joanna Kabat-Koperska,1 Agnieszka Kolasa-Wołosiuk,2 Bartosz Wojciuk,3 Iwona Wojciechowska-Koszko,3 Paulina Roszkowska,3 Barbara Krasnodębska-Szponder,3 Edyta Paczkowska,4 Krzysztof Safranow,5 Edyta Gołembiewska,1 Bogusław Machaliński,4 Kazimierz Ciechanowski1 1Department of Nephrology, Transplantology and Internal Medicine, 2Department of Histology and Embryology, 3Department of Microbiology and Immunological Diagnostics, 4Department of General Pathology, 5Department of Biochemistry and Medical Chemistry, Pomeranian Medical University, Szczecin, Poland Background: In our study, we assessed the impact of immunosuppressive drug combinations on changes in the immune system of juvenile Wistar rats exposed to these drugs during pregnancy. We primarily concentrated on changes in two organs of the immune system – the thymus and the spleen. Methods: The study was conducted on 40 (32+8 female Wistar rats administered full and half dose of drugs, respectively, subjected to regimens commonly used in therapy of human kidney transplant recipients ([1] cyclosporine A, mycophenolate mofetil, and prednisone; [2] tacrolimus, mycophenolate mofetil, and prednisone; [3] cyclosporine A, everolimus, and prednisone. The animals received drugs by oral gavage 2 weeks before pregnancy and during 3 weeks of pregnancy. Results: There were no statistically significant differences in the weight of the thymus and spleen, but changes were found in the results of blood hematology, cytometry from the spleen, and a histologic examination of the examined immune organs of juvenile Wistar rats. In the cytokine assay, changes in the level of interleukine 17 (IL-17 after increasing amounts of concanavaline A were dose-dependent; the increase of IL-17 was blocked after administration of higher doses of immunosuppressive drugs. However, after a reduction of doses, its increase resumed. Conclusion: Qualitative, quantitative, and morphological changes in the immune system of infant

  17. An advanced EPR stopped-flow apparatus based on a dielectric ring resonator

    Science.gov (United States)

    Lassmann, Günter; Schmidt, Peter Paul; Lubitz, Wolfgang

    2005-02-01

    A novel EPR stopped-flow accessory is described which allows time-dependent cw-EPR measurements of rate constants of reactions involving paramagnetic species after rapid mixing of two liquid reagents. The EPR stopped-flow design represents a state-of-the-art, computer controlled fluid driving system, a miniresonant EPR structure with an integrated small ball mixer, and a stopping valve. The X-band EPR detection system is an improved version of that reported by Sienkiewicz et al. [Rev. Sci. Instr. 65 (1994) 68], and utilizes a resonator with two stacked ceramic dielectric rings separated by a variable spacer. The resonator with the mode TE( H) 011 is tailored particularly for conditions of fast flowing and rapidly stopped aqueous solutions, and for a high time resolution. The short distance between the ball mixer and the small EPR active volume (1.8 μl) yields a measured dead time of 330 μs. A compact assembly of all parts results in minimization of disturbing microphonics. The computer controlled driving system from BioLogic with two independent stepping motors was optimized for EPR stopped-flow with a hard-stop valve. Performance tests on the EPR spectrometer ESP 300E from BRUKER using redox reactions of nitroxide radicals revealed the EPR stopped-flow accessory as an advanced, versatile, and reliable instrument with high reproducibility.

  18. Long-range dispersion interactions between Li and rare-gas atoms

    Science.gov (United States)

    Zhang, Deng-Hong; Xu, Ya-Bin; Jiang, Jun; Jiang, Li; Xie, Lu-You; Dong, Chen-Zhong

    2017-06-01

    The energy levels, oscillator strength and dipole scalar polarizabilities of Li atoms are calculated by using the relativistic semiempirical-core-potential method (RCICP). The dispersion coefficients C6 between ground 2s1/2 2p1/2,2p3/2 states of Li atom and the ground state of rare gas atoms (Ne, Ar, Kr, Xe) are calculated in JJ coupled states, in which the spin-orbital interactions are included. Present results are in good agreement with other available results. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  19. Optical oscillator strengths of the valence-shell excitations of atoms and molecules determined by the dipole ( γ,γ) method

    Science.gov (United States)

    Xu, Long-Quan; Liu, Ya-Wei; Xu, Xin; Ni, Dong-Dong; Yang, Ke; Zhu, Lin-Fan

    2017-07-01

    The dipole (γ,γ) method, which is the inelastic X-ray scattering operated at a negligibly small momentum transfer, has been developed to determine the absolute optical oscillator strengths of the valence-shell excitations of atoms and molecules. This new method is free from the line saturation effect, and its Bethe-Born conversion factor varies much more slowly with the excitation energy than that of the dipole (e, e) method. Thus the dipole (γ,γ) method provides a reliable approach to obtain the benchmark optical oscillator strengths of the valence-shell excitations for gaseous atoms and molecules. In this paper, we give a review of the dipole (γ,γ) method and some recent measurements of absolute optical oscillator strengths of gaseous atoms and molecules. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  20. Influence of residual ion polarization on the coplanar symmetric (e, 2e) cross sections for calcium and argon

    Science.gov (United States)

    Hu, Xiao-Qing; Chen, Zhan-Bin; Wang, Yang; Wang, Kai

    2017-03-01

    Detailed calculations using a modified distorted wave Born approximation (DWBA) are carried out for the triple differential cross section (TDCS) in the coplanar symmetric single ionization of calcium and argon atoms. The effects of residual ion polarization on the TDCS are investigated systematically. Our results show that the residual ion polarization, arising from the interaction between the target ion and the two outgoing electrons in the final state, may lead to a considerable change in the TDCS with a more pronounced effect in the large scattering angle region at intermediate energies. The present attempt significantly improves the agreement between theoretical and experimental results. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  1. Influence of semiclassical plasma on the energy levels and radiative transitions in highly charged ions★

    Science.gov (United States)

    Hu, Hong-Wei; Chen, Zhan-Bin; Chen, Wen-Cong; Liu, Xiao-Bin; Fu, Nian; Wang, Kai

    2017-11-01

    Considering the quantum effects of diffraction and the collective screening effects, the potential of test charge in semiclassical plasmas is derived. It is generalized exponential screened Coulomb potential. Using the Ritz variational method incorporating this potential, the effects of semiclassical plasma on the energy levels and radiative transitions are investigated systematically, taking highly charged H-like ion as an example. The Debye plasma model is also employed for comparison purposes. Comparisons and analysis are made between these two sets of results and the differences are discussed. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  2. Q and A. Poland's progress on the road to new nuclear

    International Nuclear Information System (INIS)

    Kraev, Kamen

    2017-01-01

    Conflicting reports have emerged from Poland about plans for its first reactors. Professor Grzegorz Wrochna of the Polish National Centre for Nuclear Research says the programme is on track and a business model is expected soon. The previous government's programme calls for 6 GW in two locations. The government recently published a strategy for responsible development which calls for the nuclear programme to be sped up. However, no capacity figures were included. The industry should not be bound by a rigid number. In time, maybe we will speak of 4 GW or 12 GW, but it will depend on market needs and financial possibilities. The biggest risks do not come from cancellation or public opinion. They come from delays.

  3. Q and A. Poland's progress on the road to new nuclear

    Energy Technology Data Exchange (ETDEWEB)

    Kraev, Kamen [NucNet, Brussels (Belgium)

    2017-06-15

    Conflicting reports have emerged from Poland about plans for its first reactors. Professor Grzegorz Wrochna of the Polish National Centre for Nuclear Research says the programme is on track and a business model is expected soon. The previous government's programme calls for 6 GW in two locations. The government recently published a strategy for responsible development which calls for the nuclear programme to be sped up. However, no capacity figures were included. The industry should not be bound by a rigid number. In time, maybe we will speak of 4 GW or 12 GW, but it will depend on market needs and financial possibilities. The biggest risks do not come from cancellation or public opinion. They come from delays.

  4. Pamięć o Zagładzie w perspektywie historyka teatru

    Directory of Open Access Journals (Sweden)

    Jacek Popiel

    2015-11-01

    Full Text Available In his Polski teatr Zagłady [The Polish Theater of the Holocaust], Grzegorz Niziołek, who starts with theater and specific theatrical performances and who focuses on artistic phenomena, presents problems that go far beyond art. This is a book that should be read by historians, literary scholars, political scientists and cultural experts. Sociologists and psychologists who study social behavior will also find some of its sections interesting. This Cracow theatrologist presents the extermination of Jews during the occupation of Poland as well as Polish-Jewish relations, i.e. one of the most difficult Polish problems, permeated with silence and resentment, in the form of a monograph and in relation to the history of post-war theater, of which it is an important part.

  5. See Also:physica status solidi (a)physica status solidi (c)Copyright © 2004 WILEY-VCH Verlag GmbH & Co. KGaA, WeinheimGet Sample CopyFree Online Trial -->Recommend to Your LibrarianSave Title to My ProfileSet E-Mail Alert language="javascript">var homepagelinks = new Array(new Array("Journal Home","/cgi-bin/jhome/40001185",""),new Array("Issues","/cgi-bin/jtoc/40001185/",""),new Array("Early View","/cgi-bin/jeview/40001185/",""),new Array("News","/cgi-bin/jabout/40001185/news/index.html",""),new Array("Reviews","/cgi-bin/jabout/40001185/reviews.html",""),new Array("Read Cover Story","/cgi-bin/jabout/40001185/cover/2232/current.html","e"),new Array("","","s"),new Array("Product Information","/cgi-bin/jabout/40001185/2232_info.html",""),new Array("Editorial Board","/cgi-bin/jabout/40001185/edbd.html",""),new Array("For Authors","/cgi-bin/jabout/40001185/authors.html",""),new Array("For Referees","/cgi-bin/jabout/40001185/refserv.html",""),new Array("Subscribe","http://jws-edcv.wiley.com/jcatalog/JournalsCatalogOrder/JournalOrder?PRINT_ISSN=0370-1972",""),new Array("Contact","/cgi-bin/jabout/40001185/contact.html",""),new Array("","","x"));writeJournalLinks("", "40001185");Volume 241, Issue5 (April 2004)Articles in the Current Issue:Cover PictureHorizontal line nodes in superconducting Sr2RuO4

    Science.gov (United States)

    Litak, G.; Annett, J. F.; Györffy, B. L.; Wysokiski, K. I.

    2004-04-01

    Superconductivity in Sr2RuO4 is one of the most interesting phenomena in current condensed matter physics, since it is revealed to be a triplet-pairing state. Our Editor's Choice [1] considers an important problem related to the type of order parameter in this material.The position of line nodes on the Fermi surface, as evident from recent measurements, has been determined for various scenarios shown in the cover picture. Using these models, the temperature dependence of heat capacity and penetration depth has been calculated for easy comparison with experiments.The first author, Grzegorz Litak, is assistant professor at Technical University of Lublin and visiting scientist at the Max Planck Institute in Dresden. He is working on the effect of disorder on correlated and exotic superconductors, nonlinear dynamics, and superconductivity in strontium ruthenate.

  6. Influence of caffeine and hyaluronic acid on collagen biosynthesis in human skin fibroblasts

    Directory of Open Access Journals (Sweden)

    Donejko M

    2014-10-01

    Full Text Available Magdalena Donejko,1 Andrzej Przylipiak,1 Edyta Rysiak,2 Katarzyna Głuszuk,2 Arkadiusz Surażyński2 1Department of Esthetic Medicine, 2Department of Medicinal Chemistry, Faculty of Pharmacy, Medical University of Białystok, Białystok, Poland Aim: The aim of this study was to evaluate the effect of caffeine on collagen biosynthesis in human skin fibroblasts and the influence of hyaluronic acid (HA on this process. Materials and methods: Collagen, [3H]-thymidine incorporation, and prolidase activity were measured in confluent human skin fibroblast cultures that had been treated with 1, 2, and 5 mM caffeine and with caffeine and 500 µg/mL HA. Western immunoblot analysis was performed to evaluate expression of ß1-integrin receptor, insulin-like growth factor receptor phospho-Akt protein and mitogen-activated protein kinase (phospho-extracellular signal-regulated kinase. Results: Caffeine inhibited collagen biosynthesis in a dose-dependent manner. The mechanism of this process was found at the level of prolidase activity. Caffeine significantly inhibited the enzyme activity. The addition of HA had no effect on collagen biosynthesis or prolidase activity in fibroblasts incubated with caffeine. Caffeine also had an inhibitory effect on DNA biosynthesis. HA, however, did not have any significant effect on this process. The inhibition of the expression of ß1-integrin and insulin-like growth factor receptor in fibroblasts incubated with the caffeine indicates a possible mechanism of inhibition of collagen biosynthesis. Conclusion: Caffeine reduces collagen synthesis in human cultured skin fibroblasts. HA did not have any significant protective effect on this process. This is the first study to our knowledge that reports caffeine-induced inhibition of collagen synthesis in human skin fibroblasts. Keywords: collagen, caffeine, hyaluronic acid, fibroblast

  7. Therapy of psoriasis with narrowband ultraviolet-B light influences plasma concentrations of MMP-2 and TIMP-2 in patients

    Directory of Open Access Journals (Sweden)

    Głażewska EK

    2016-10-01

    Full Text Available Edyta Katarzyna Głażewska,1 Marek Niczyporuk,1 Sławomir Ławicki,2 Maciej Szmitkowski,2 Monika Zajkowska,2 Grażyna Ewa Będkowska,3 Andrzej Przylipiak1 1Department of Esthetic Medicine, 2Department of Biochemical Diagnostics, 3Department of Haematological Diagnostics, Medical University, Białystok, Poland Background: Matrix metalloproteinases (MMPs, which show a significant ability to cleave the components of extracellular matrix, and tissue inhibitors of metalloproteinases (TIMPs, which slow down the activity of those enzymes, may be implicated in the pathogenesis and spread of psoriatic disease. This study aims to analyze plasma levels of MMP-2 and TIMP-2 in plaque psoriasis patients before and after the course of narrowband ultraviolet-B (NBUVB therapy with respect to disease advancement. Patients and methods: A total of 49 patients suffering from plaque psoriasis and 40 healthy volunteers were enrolled into the study. Plasma levels of MMP-2 and TIMP-2 were determined using enzyme-linked immunosorbent assay, while Psoriasis Area and Severity Index (PASI was used to define the disease advancement. Results: The results showed increased plasma levels of MMP-2 and TIMP-2, but this change was significant only in case of MMP-2 in total psoriatic group compared to healthy subjects. Moreover, there was an increase in the concentrations of chosen factors with an increase in the severity of the disease. The NBUVB therapy causes a decline in the concentration of the analyzed enzyme and its inhibitor, although this change was statistically significant in the total psoriatic group only in case of MMP-2. There was also a positive correlation between MMP-2, TIMP-2, and PASI score value. Conclusion: Our study highlights a possible important role of MMP-2 in the activity of psoriasis and clearance of disease symptoms. Moreover, plasma MMP-2 seems to be a valuable psoriasis biomarker. Keywords: gelatinase A, matrix metalloproteinases, tissue inhibitor of

  8. Collisional-radiative model including recombination processes for W27+ ion★

    Science.gov (United States)

    Murakami, Izumi; Sasaki, Akira; Kato, Daiji; Koike, Fumihiro

    2017-10-01

    We have constructed a collisional-radiative (CR) model for W27+ ions including 226 configurations with n ≤ 9 and ł ≤ 5 for spectroscopic diagnostics. We newly include recombination processes in the model and this is the first result of extreme ultraviolet spectrum calculated for recombining plasma component. Calculated spectra in 40-70 Å range in ionizing and recombining plasma components show similar 3 strong lines and 1 line weak in recombining plasma component at 45-50 Å and many weak lines at 50-65 Å for both components. Recombination processes do not contribute much to the spectrum at around 60 Å for W27+ ion. Dielectronic satellite lines are also minor contribution to the spectrum of recombining plasma component. Dielectronic recombination (DR) rate coefficient from W28+ to W27+ ions is also calculated with the same atomic data in the CR model. We found that larger set of energy levels including many autoionizing states gave larger DR rate coefficients but our rate agree within factor 6 with other works at electron temperature around 1 keV in which W27+ and W28+ ions are usually observed in plasmas. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, and Grzegorz Karwasz.

  9. Correlation, Breit and Quantum Electrodynamics effects on energy level and transition properties of W54+ ion

    Science.gov (United States)

    Ding, Xiaobin; Sun, Rui; Koike, Fumihiro; Kato, Daiji; Murakami, Izumi; Sakaue, Hiroyuki A.; Dong, Chenzhong

    2017-03-01

    The electron correlation effects and Breit interaction as well as Quantum Electro-Dynamics (QED) effects were expected to have important contribution to the energy level and transition properties of heavy highly charged ions. The ground states [Ne]3s23p63d2 and first excited states [Ne]3s23p53d3 of W54+ ion have been studied by using Multi-Configuration Dirac-Fock method with the implementation of Grasp2K package. A restricted active space method was employed to investigate the correlation contribution from different models. The Breit interaction and QED effects were taken into account in the relativistic configuration interaction calculation with the converged wavefunction. It is found that the correlation contribution from 3s and 3p orbital have important contribution to the energy level, transition wavelength and probability of the ground and the first excited state of W54+ ion. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  10. Theoretical study of the dielectronic recombination process of Li-like Xe51+ ions

    Science.gov (United States)

    Dou, Lijun; Xie, Luyou; Zhang, Denghong; Dong, Chenzhong; Wen, Weiqiang; Huang, Zhongkui; Ma, Xinwen

    2017-05-01

    The dielectronic recombination of Li-like Xe51+ (2s) ions was studied using the flexible atomic code based on the relativistic configuration interaction method. The resonance energies, radiative and autoionization rates, and resonance strengths were calculated systematically for the doubly excited states (2p1/2nlj)J(n = 18-32) and (2p3/2n'lj)J(n' = 9-27) of Be-like Xe50+ ions. For the higher Rydberg resonance states with n ≥ 33 and n' ≥ 28, the resonance energies and strengths were obtained by extrapolation based on quantum defect theory. The theoretical rate coefficients, covering the center-of-mass energy range 0-505 eV, are in a better agreement with the experimental results measured at the heavy-ion storage ring ESR than the Multi-Configuration Dirac-Fock calculations, especially at the resonance energy range close to the series limits. Contribution to the Topical Issue: "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  11. Low-energy and very-low energy total cross sections for electron collisions with N2

    Science.gov (United States)

    Kitajima, Masashi; Kishino, Takaya; Okumura, Takuma; Kobayashi, Naomasa; Sayama, Atsushi; Mori, Yuma; Hosaka, Kouichi; Odagiri, Takeshi; Hoshino, Masamitsu; Tanaka, Hiroshi

    2017-06-01

    Absolute grand total cross sections for electron scattering from N2 are obtained in the energy range from 20 eV down to 5 meV with very narrow electron energy width of 9 meV using the threshold-photoelectron source. Total cross sections obtained in the present study are compared with the previous experimentally obtained results. At the very-low energy region below 50 meV, the present total cross sections are somewhat smaller than those reported by the Aarhus group [S.V. Hoffmann et al., Rev. Sci. Instrum. 73, 4157 (2002)], which has been the only experimental work that provided the total cross sections in the very-low energy region. The energy positions of the peaks in the total cross sections due to the 2Πg shape resonance are obtained with higher accuracy, due to the improved uncertainty of the energy position in the present measurement compared to the previous works. The resonance structure in the total cross sections due to the Feshbach resonances of N2 at around 11.5 eV are also observed. Analysis of the resonant structure was carried out in order to determine the values of resonance width of Feshbach resonances of N2. Contribution to the Topical Issue: "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  12. Electron scattering on molecules: search for semi-empirical indications

    Science.gov (United States)

    Fedus, Kamil; Karwasz, Grzegorz P.

    2017-06-01

    Reliable cross-sections for electron-molecule collisions are urgently needed for numerical modeling of various processes important from technological point of view. Unfortunately, a significant progress in theory and experiment over the last decade is not usually accompanied by the convergence of cross-sections measured at different laboratories and calculated with different methods. Moreover the most advanced contemporary theories involve such large basis sets and complicated equations that they are not easily applied to each specific molecule for which data are needed. For these reasons the search for semi-empirical indications in angular and energy dependencies of scattering cross-section becomes important. In this paper we make a brief review of the applicability of the Born-dipole approximation for elastic, rotational, vibrational and ionization processes that can occur during electron-molecule collisions. We take into account the most recent experimental findings as the reference points. Contribution to the Topical Issue "Atomic and Molecular Data and Their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, and Grzegorz Karwasz.

  13. MCDF calculations of Auger cascade processes

    Science.gov (United States)

    Beerwerth, Randolf; Fritzsche, Stephan

    2017-10-01

    We model the multiple ionization of near-neutral core-excited atoms where a cascade of Auger processes leads to the emission of several electrons. We utilize the multiconfiguration Dirac-Fock (MCDF) method to generate approximate wave functions for all fine-structure levels and to account for all decays between them. This approach allows to compute electron spectra, the population of final-states and ion yields, that are accessible in many experiments. Furthermore, our approach is based on the configuration interaction method. A careful treatment of correlation between electronic configurations enables one to model three-electron processes such as an Auger decay that is accompanied by an additional shake-up transition. Here, this model is applied to the triple ionization of atomic cadmium, where we show that the decay of inner-shell 4p holes to triply-charged final states is purely due to the shake-up transition of valence 5s electrons. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  14. LINAC4 takes a tour of Europe

    CERN Multimedia

    Katarina Anthony

    2011-01-01

    Along the German Autobahnen, a truck carrying 20 tonnes of copper is on its way to Poland. The metal has already made a short tour of Europe, yet the drive across the high-speed highway is only the beginning of its transformation into CERN’s next linear accelerator, LINAC4.   Grzegorz Wrochna (left), director of the Andrzej Soltan Institute for Nuclear Studies (IPJ), and Rolf Heuer (right), CERN DG, sign the framework agreement between the two institutes. By the summer of 2012, the PI-Mode Structures (PIMS) will be constructed and completely installed in the LINAC4 tunnel. The PIMS cavities are the final accelerating structures needed for LINAC4, and have been designed to accelerate protons from 100 to 160MeV. While the first cavity was built entirely at CERN, construction of the remaining cavities has become a larger, multi-national operation. In a 1 million euro framework agreement signed on 11 February by the Director-General, the Andrzej Soltan Institute for Nuclear Studies in Swie...

  15. Patients’ knowledge of heart failure and their perception of the disease

    Directory of Open Access Journals (Sweden)

    Płotka A

    2017-08-01

    Full Text Available Anna Płotka,1 Edyta Prokop,2 Jacek Migaj,2 Ewa Straburzyńska–Migaj,2 Stefan Grajek2 1Medical Faculty I, Poznań University of Medical Sciences, Poznań, Poland, 21st Department of Cardiology, University Hospital of Lord’s Transfiguration, Poznań University of Medical Sciences, Poznań, Poland Purpose: The aim of this study was to gain a deeper insight into patients’ perception of chronic heart failure (CHF symptoms by analyzing their compliance with nonpharmacological recommendations. Patients and methods: This was a prospective, single-center survey-based registry. Patients included in this study were hospitalized between December 2014 and January 2016 at the 1st Department of Cardiology, University Hospital of Lord’s Transfiguration, Poznan´ University of Medical Sciences, and had been diagnosed with CHF at least 3 months prior to inclusion. Participants were divided according to New York Heart Association (NYHA functional class into mild CHF (NYHA I and II and severe CHF (NYHA III and IV, and according to age into young (<50 years, middle-aged (50–70 years and old (>70 years. The survey included information about the patients’ sex, age, education, length of the illness and 12 questions about their perception of CHF. This study included 201 patients. The mean age was 58±15 years. Results: The younger the patients, the more often they thought that CHF is curable. The patients presenting with severe CHF tended to think that CHF is incurable significantly more often than those with mild CHF. Most of the patients considered loss of appetite, cough and vomiting the least alarming symptoms. Significantly more patients with severe CHF exercised less and reported reduced sexual activity more often in comparison to the mild CHF patients. Most of the young patients reported no changes to their sexual activity, body mass index (BMI or exercise after diagnosis of CHF. Most of the old patients exercised less than before diagnosis of CHF

  16. Design of ITER divertor VUV spectrometer and prototype test at KSTAR tokamak

    Science.gov (United States)

    Seon, Changrae; Hong, Joohwan; Song, Inwoo; Jang, Juhyeok; Lee, Hyeonyong; An, Younghwa; Kim, Bosung; Jeon, Taemin; Park, Jaesun; Choe, Wonho; Lee, Hyeongon; Pak, Sunil; Cheon, MunSeong; Choi, Jihyeon; Kim, Hyeonseok; Biel, Wolfgang; Bernascolle, Philippe; Barnsley, Robin; O'Mullane, Martin

    2017-12-01

    Design and development of the ITER divertor VUV spectrometer have been performed from the year 1998, and it is planned to be installed in the year 2027. Currently, the design of the ITER divertor VUV spectrometer is in the phase of detail design. It is optimized for monitoring of chord-integrated VUV signals from divertor plasmas, chosen to contain representative lines emission from the tungsten as the divertor material, and other impurities. Impurity emission from overall divertor plasmas is collimated through the relay optics onto the entrance slit of a VUV spectrometer with working wavelength range of 14.6-32 nm. To validate the design of the ITER divertor VUV spectrometer, two sets of VUV spectrometers have been developed and tested at KSTAR tokamak. One set of spectrometer without the field mirror employs a survey spectrometer with the wavelength ranging from 14.6 nm to 32 nm, and it provides the same optical specification as the spectrometer part of the ITER divertor VUV spectrometer system. The other spectrometer with the wavelength range of 5-25 nm consists of a commercial spectrometer with a concave grating, and the relay mirrors with the same geometry as the relay mirrors of the ITER divertor VUV spectrometer. From test of these prototypes, alignment method using backward laser illumination could be verified. To validate the feasibility of tungsten emission measurement, furthermore, the tungsten powder was injected in KSTAR plasmas, and the preliminary result could be obtained successfully with regard to the evaluation of photon throughput. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  17. Dupuytren Disease: Is There Enough Comprehensive Patient Information on the Internet?

    Science.gov (United States)

    Zuk, Grzegorz; Reinisch, Katharina B; Raptis, Dimitri A; Fertsch, Sonia; Guggenheim, Merlin; Palma, Adrian F

    2017-06-22

    Dupuytren disease is a chronic nonmalign fibroproliferative disorder that causes finger contractures via proliferation of new tissue under the glabrous skin of the hand, resulting in multiple functional limitations for the patient. As many surgical therapy options exist, patients suffering from this condition actively search for information in their environment before consulting a health professional. As little is known about the quality of Web-based patient information, the aim of this study was to conduct its systematic evaluation using a validated tool. A total of 118 websites were included, and qualitative and quantitative assessment was performed using the modified Ensuring Quality Information for Patients (EQIP) tool. This standardized and reproducible tool consists of 36 items to assess available information in three categories: contents, identification, and structure data. Scientific data with restricted access, duplicates, and irrelevant websites were not included. Only 32 websites addressed more than 19 items, and the scores did not significantly differ among the website developers. The median number of items from the EQIP tool was 16, with the top websites addressing 28 out of 36 items. The quality of the newly developed websites did not increase with passing time. This study revealed several shortcomings in the quality of Web-based information available for patients suffering from Dupuytren disease. In the world of continuously growing and instantly available Web-based information, it is the health providers' negligence of the last two decades that there are very few good quality, informative, and educative websites that could be recommended to patients. ©Grzegorz Zuk, Katharina B Reinisch, Dimitri A Raptis, Sonia Fertsch, Merlin Guggenheim, Adrian F Palma. Originally published in the Interactive Journal of Medical Research (http://www.i-jmr.org/), 22.06.2017.

  18. Long-term administration of high doses of transdermal buprenorphine in cancer patients with severe neuropathic pain

    Directory of Open Access Journals (Sweden)

    Leppert W

    2015-12-01

    Full Text Available Wojciech Leppert, Grzegorz Kowalski Chair and Department of Palliative Medicine, Poznan University of Medical Sciences, Poznan, Poland Background: Buprenorphine is often administered by the transdermal route (transdermal buprenorphine [TB] in cancer patients with severe neuropathic pain. However, high doses of TB of 140 µg/h are rarely used.Patients and methods: Three cancer patients with severe neuropathic Numeric Rating Scale (NRS pain scores of 8–10 who were successfully treated with high doses of TB up to 140 µg/h along with other opioids and adjuvant analgesics.Results: TB was administered for a long period of follow-up (9 months to 4 years, including 34–261 days of treatment with the dose of 140 µg/h, which allowed achievement of satisfactory analgesia (NRS 3–5 and good treatment tolerance. In all three patients, TB dose was gradually titrated from 35 to 140 µg/h, and all patients used morphine at least for some time for breakthrough and background pain management along with adjuvant analgesics. Two patients continued the treatment with TB until the end of life, and one patient is still receiving the treatment.Conclusion: TB at doses of up to 140 µg/h in cancer patients with severe neuropathic pain seems to be effective and safe in combination with other opioids and with adjuvant analgesics, and may significantly improve patients’ quality of life. Clinical studies may explore higher than maximal 140 µg/h TB doses recommended by a manufacturer, and also in combination with other opioids and adjuvant analgesics. Keywords: adverse effects, analgesia, cancer, neuropathic pain, transdermal buprenorphine, treatment

  19. Lidii Zamkow: Pamięć – niepamięć – re/mistyfikacja

    Directory of Open Access Journals (Sweden)

    Ewa Łubieniewska

    2015-05-01

    scared the opportunists. ”The Lower Depths staged in Krakow (1960 almost clinically reveals the weaknesses of our critical work”, stated openly Marian Sienkiewicz in his article on the Russian current (his favourite in Zamkow’s work (especially memorable creations are Dostoevsky’s Uncle’s Dream, Tolstoy’s Resurrection, and Sholokhov’s Quietly Flows the Don. The director continually evoked controversy by breaking up with the traditional rules of staging Brecht and Dürenmatt (she showed The Visit in the convention of a cruel fairy-tale. She interpreted Shakespeare’s tragedies and comedies from the perspective of Jan Kott’s thought, giving the staging a modern theatrical shape. In Kafka’s Amerika (1968 she demystified two utopias of the promised land: the American prosperity and the “community of the dispossessed” (Ameryka, in ”Tygodnik Powszechny” 1968, no. 39, effectively applying the poetics of silent movies to the organization of stage movement in some scenes. True to her concept of the theatre, she did not yield to the dictate of the elites. The fierce attacks on her creation of the Apparitions in The Wedding were in fact voices in a debate on the new language of the theatre, in which an unpredictable, multifaceted metaphor replaces stage stereotypes. The fact that this artist’s phenomenon has not been examined yet does not prove her “mediocrity” (which was unjustly and wrongly suggested by the RE//MIX deconstructors, but rather implies that the critics are not yet ready to accept the challenge to comprehend the productivity and complexity of Zamkow’s artistic personality.

  20. Electron impact ionization cross section studies of C2Fx (x = 1 - 6) and C3Fx (x = 1 - 8) fluorocarbon species

    Science.gov (United States)

    Gupta, Dhanoj; Choi, Heechol; Song, Mi-Young; Karwasz, Grzegorz P.; Yoon, Jung-Sik

    2017-05-01

    The total ionization cross section for C2Fx (x = 1 - 6) and C3Fx (x = 1 - 8) fluorocarbon species are studied with the Binary-Encounter Bethe (BEB) model using various orbital parameters calculated from restricted/unrestricted Hartree-Fock (RHF/UHF) and Density Functional Theory (DFT). All the targets were optimized for their minimal structures and energies with several ab-initio methods with the aug-cc-pVTZ basis set. Among them, the present results with RHF/UHF orbital energies showed good agreement with the experimental results for stable targets C2F6, C2F4, C3F6 and C3F8. The results with the DFT (ωB97X/ωB97X-D) showed a reasonable agreement with the recent calculation of Bull et al. [J.N. Bull, M. Bart, C. Vallance, P.W. Harland, Phys. Rev. A 88, 062710 (2013)] for C2F6, C3F6 and C3F8 targets. The ionization cross section for C2F, C2F2, C2F3, C3F, C3F2, C3F3, C3F4, C3F5 and C3F7 were computed for the first time in the present study. We have also computed the vertical ionization potentials and polarizability for all the targets and compared them with other experimental and theoretical values. A good agreement is found between the present and the previous results. The calculated polarizability in turn is used to study the correlation with maximum ionization cross section and in general a good correlation is found among them, confirming the consistency and reliability of the present data. The cross section data reported in this article are very important for plasma modeling especially related to fluorocarbon plasmas. Contribution to the Topical Issue "Atomic and Molecular Data and their Applications", edited by Gordon W.F. Drake, Jung-Sik Yoon, Daiji Kato, Grzegorz Karwasz.

  1. Incidence and mortality rates in breast, corpus uteri, and ovarian cancers in Poland (1980–2013: an analysis of population-based data in relation to socio-economic changes

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    Banas T

    2016-09-01

    Full Text Available Tomasz Banas,1 Grzegorz Juszczyk,2 Kazimierz Pitynski,1 Dorota Nieweglowska,1 Artur Ludwin,1 Aleksandra Czerw2 1Department of Gynecology and Oncology, Jagiellonian University Medical College, Krakow, 2Faculty of Health Science, Medical University of Warsaw, Warsaw, Poland Objectives: This study aimed to analyze incidence and mortality trends in breast cancer (BC, corpus uteri cancer (CUC, and ovarian cancer (OC in Poland in the context of sociodemographic changes.Materials and methods: Incidence and mortality data (1980–2013 were retrieved from the Polish National Cancer Registry, while socioeconomic data (1960–2013 were obtained from the World Bank. Age-standardized incidence and mortality rates were calculated by direct standardization, and join-point regression was performed to describe trends using the average annual percentage change (AAPC.Results: A significant decrease in birth and fertility rates and a large increase in gross domestic product were observed together with a decrease in the total mortality rate among women, as well as an increase in life expectancy for women. A large, significant increase in BC incidence was observed (AAPC1980–1990 2.14, AAPC1990–1996 4.71, AAPC1996–2013 2.21, with a small but significant decrease in mortality after a slight increase (AAPC1980–1994 0.52, AAPC1994–2013 −0.66. During the period 1980–2013, a significant increase in CUC incidence (AAPC1980–1994 3.7, AAPC1994–2013 1.93 was observed, with an initial mortality-rate reduction followed by a significant increase (AAPC1980–2006 −1.12, AAPC2006–2013 3.74. After the initial increase of both OC incidence and mortality from 1994, the incidence rate decreased significantly (AAPC1980–1994 2.98, AAPC1994–2013 −0.49, as did the mortality rate (AAPC1980–1994 0.52, AAPC1994–2013 −0.66.Conclusion: After 1994, a decrease in OC incidence was found, while the incidence of BC and CUC continued to increase. A reduction in

  2. Efficacy and safety of a vaginal medicinal product containing three strains of probiotic bacteria: a multicenter, randomized, double-blind, and placebo-controlled trial

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    Tomusiak A

    2015-09-01

    Full Text Available Anna Tomusiak,1 Magdalena Strus,1 Piotr B Heczko,1 Paweł Adamski,2 Grzegorz Stefański,3 Aleksandra Mikołajczyk-Cichońska,3 Magdalena Suda-Szczurek3 1Department of Microbiology, Jagiellonian University Medical College, 2Institute of Nature Conservation, Polish Academy of Sciences, 3IBSS BIOMED SA, Kraków, Poland Objective: The main objective of this study was to evaluate whether vaginal administration of probiotic Lactobacillus results in their colonization and persistence in the vagina and whether Lactobacillus colonization promotes normalization and maintenance of pH and Nugent score. Patients and methods: The study was a multicenter, randomized, double-blind, and placebo-controlled trial. Altogether, 376 women were assessed for eligibility, and signed informed consent. One hundred and sixty eligible women with abnormal, also called intermediate, vaginal microflora, as indicated by a Nugent score of 4–6 and pH >4.5 and zero or low Lactobacillus count, were randomized. Each participant was examined four times during the study. Women were randomly allocated to receive either the probiotic preparation inVag®, or a placebo (one capsule for seven consecutive days vaginally. The product inVag includes the probiotic strains Lactobacillus fermentum 57A, Lactobacillus plantarum 57B, and Lactobacillus gasseri 57C. We took vaginal swabs during visits I, III, and IV to determine the presence and abundance of bacteria from the Lactobacillus genus, measure the pH, and estimate the Nugent score. Drug safety evaluation was based on analysis of the types and occurrence of adverse events. Results: Administration of inVag contributed to a significant decrease (between visits in both vaginal pH (P<0.05 and Nugent score (P<0.05, and a significant increase in the abundance of Lactobacillus between visit I and visits III and IV (P<0.05. Molecular typing revealed the presence of Lactobacillus strains originating from inVag in 82% of women taking the drug at

  3. Analysis concerning nutritional behaviors in the context of the risk of orthorexia

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    Olejniczak D

    2017-02-01

    Full Text Available Dominik Olejniczak,1 Dorota Bugajec,1 Mariusz Panczyk,2 Anna Brytek-Matera,3 Urszula Religioni,4 Aleksandra Czerw,1 Aleksandra Grąbczewska,1 Grzegorz Juszczyk,1 Karolina Jabłkowska-Górecka,1 Anna Staniszewska5 1Department of Public Health, Faculty of Health Science, Medical University of Warsaw, 2Division of Teaching and Outcomes of Education, Faculty of Health Science, Warsaw Medical University, 3Faculty of Psychology, SWPS University of Social Sciences and Humanities, Katowice, 4Collegium of Socio-Economics, Warsaw School of Economics, 5Department of Experimental and Clinical Pharmacology, Medical University of Warsaw, Warsaw, Poland Abstract: Orthorexia is recognized as an eating disorder, an obsessive–compulsive spectrum disorder, or a somatoform disorder. The aim of our research was to analyze nutritional behaviors for the assessment of the risk of orthorexia. The authors developed a questionnaire in which 981 respondents participated and used it as a research method. Both men and women ate mostly 4–5 meals per day (46.30% women versus 34.74% men; however, more men than women ate 1–2 meals daily (18.95% men versus 7.9% women. Both place of birth and field of study did not differ in terms of the number of meals. Moreover, it was observed that the number of meals per day was correlated with the declared time spent on planning a diet. People who ate over 3 meals per day more often indicates that they spent >3 h per day on planning their diet in comparison with people who ate only 1–2 meals. Only 17.6% of the respondents declared that they most often ate meals in a company of someone, whereas 45.3% indicated that there was no rule. The remaining 37.1% of the respondents most often consumed their meals alone. Almost twice as many men as women never paid attention to the qualitative composition of nutrition. Women followed a slimming diet more often than men (20.3% versus 5.8% and this indicated >4 attempts of losing weight

  4. Lumbar paravertebral blockade as intractable pain management method in palliative care

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    Zaporowska-Stachowiak I

    2013-09-01

    Full Text Available Iwona Zaporowska-Stachowiak,1,2 Aleksandra Kotlinska-Lemieszek,3 Grzegorz Kowalski,3 Katarzyna Kosicka,4 Karolina Hoffmann,5 Franciszek Główka,4 Jacek Łuczak2 1Department of Pharmacology, 2Palliative Medicine In-patient Unit, University Hospital of Lord’s Transfiguration, 3Department of Palliative Care, 4Department of Physical Pharmacy and Pharmacokinetics, 5Department of Internal Medicine, Metabolic Disorders and Arterial Hypertension, Poznan University of Medical Sciences, Poznan, Poland Abstract: Optimal symptoms control in advanced cancer disease, with refractory to conventional pain treatment, needs an interventional procedure. This paper presents coadministration of local anesthetic (LA via paravertebral blockade (PVB as the alternative to an unsuccessful subcutaneous fentanyl pain control in a 71-year old cancer patient with pathological fracture of femoral neck, bone metastases, and contraindications to morphine. Bupivacaine in continuous infusion (0.25%, 5 mL · hour-1 or in boluses (10 mL of 0.125%–0.5% solution, used for lumbar PVB, resulted in pain relief, decreased demand for opioids, and led to better social interactions. The factors contributing to an increased risk of systemic toxicity from LA in the patient were: renal impairment; heart failure; hypoalbuminemia; hypocalcemia; and a complex therapy with possible drug–drug interactions. These factors were taken into consideration during treatment. Bupivacaine’s side effects were absent. Coadministered drugs could mask LA’s toxicity. Elevated plasma α1-acid glycoprotein levels were a protective factor. To evaluate the benefit-risk ratio of the PVB treatment in boluses and in constant infusion, bupivacaine serum levels were determined and the drug plasma half-lives were calculated. Bupivacaine’s elimination was slower when administered in constant infusion than in boluses (t½ = 7.80 hours versus 2.64 hours. Total drug serum concentrations remained within the safe

  5. Analgesic efficacy, adverse effects, and safety of oxycodone administered as continuous intravenous infusion in patients after total hip arthroplasty

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    Olczak B

    2017-05-01

    Full Text Available Bogumił Olczak,1 Grzegorz Kowalski,1,2 Wojciech Leppert,2 Iwona Zaporowska-Stachowiak,3 Katarzyna Wieczorowska-Tobis2 1Department of Anesthesiology, Józef Struś Multiprofile Municipal Hospital, 2Department of Palliative Medicine, Poznan University of Medical Sciences, 3Department of Pharmacology, Poznan University of Medical Sciences, Poland Background: Total hip arthroplasty (THA causes extensive tissue damage and severe pain. This study aimed to assess the analgesic efficacy, adverse effects (AEs, and safety of continuous intravenous (iv oxycodone infusion with ketoprofen (injected into the iv line in patients after THA, and to assay serum oxycodone levels.Patients and methods: Fourteen patients, aged 59‒82 years with American Society of Anesthesiologists (ASA classification I or III, underwent THA with intrathecal analgesia and sedation induced by iv propofol. After the surgery, oxycodone (continuous iv infusion at a dose of 1 mg/h (five patients or 2 mg/h (nine patients with 100 mg ketoprofen (injected into the iv line was administered to each patient every 12 h. Pain was assessed using a numerical rating scale (NRS: 0 – no pain, 10 – the most severe pain at rest and during movement. AEs, including hemodynamic unsteadiness, nausea, vomiting, pruritus, cognitive impairment, and respiratory depression, were registered during the first 24 h after surgery.Results: Oxycodone (continuous iv infusion at a dose of 2 mg/h with ketoprofen (100 mg administered every 12 h provided satisfactory analgesia in all nine patients without the need of rescue analgesics within the first 24 h after THA. In three out of five patients, oxycodone at 1 mg/h was effective. Oxycodone did not induce drowsiness, vomiting, pruritus, respiratory depression, or changes in blood pressure. Bradycardia appeared in two patients, and nausea was observed in one patient.Conclusion: Oxycodone infusion with ketoprofen administered by iv is effective in patients after THA

  6. Polish Literature of the Holocaust. The First Instalment: 1939-1968

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    Katarzyna Kuczyńska-Koschany

    2015-01-01

    Full Text Available The text is a critical attempt discussing the compendium Literatura polska wobec Zagłady, (“Polish Literature in the Face of the Holocaust” edited and published by three prominent scholarly experts on the subject: Sławomir Buryła, Dorota Krawczyńska and Jacek Leociak. This is the first of the three volumes of the series Reprezentacje Zagłady w kulturze polskiej (“Representations of the Holocaust in Polish Culture” – an endeavour which is imposing already in its first instalment concerning the years 1939-1968. The time frame of the abovementioned volume is marked by the date of the beginning of World War II (1939, resulting in the Holocaust of the Jews of Europe, and a “dry pogrom”, that is was the anti-Semitic campaign in Poland in 1968 (the campaign itself and its writings shall be examined in the following volume. A comprehensive and very carefully prepared monograph has been divided into two fundamental parts: concerning the literature reacting to the Holocaust conducted by Nazi Germany during the war (1939-1945 and discussing the literary echoes of that genocide in the years 1945-1968. The study and invaluable interpretational effort have been focused on personal document literature (Marta Janczewska, Jacek Leociak, the prose (Sławomir Buryła, Dorota Krawczyńska, the poetry (Piotr Matywiecki and the press (Ewa Koźmińska-Frejlak. A separate chapter has been devoted to a the “global text”, i.e., Archiwum Ringelbluma (“Ringelblum’s Archives”. Highly appreciating the entire volume as well as its individual fragments, recalling fundamental considerations and the ones concerning details, finally, proposing small corrections and pointing to minor shortcomings, the author of the critical review suggests the use of the formula “Polish literature of the Holocaust” (analogous to the formula coined by Grzegorz Niziołek “Polish theatre of the Holocaust” as the one principally necessary to be contrasted with the

  7. Identifying Bright X-Ray Beasts

    Science.gov (United States)

    Kohler, Susanna

    2017-10-01

    accreting object. This provided strong support for the second model of ULXs as X-ray binaries with super-Eddington luminosity.But could this model in fact account for all ULXs? A team of authors led by Grzegorz Wiktorowicz (Kavli Institute for Theoretical Physics, UC Santa Barbara and Warsaw University, Poland) says yes.Time evolution of the number of ULXs since the beginning of star formation, for a star formation burst (left panels) and continuous star formation (right panels), and for solar-metallicity (top panels) and low-metallicity (bottom panels) environments. The heavy solid line shows ULXs with black-hole accretors, the dashed line ULXs with neutron-star accretors, and the solid line the total. [Wiktorowicz et al. 2017]No Exotic Objects NeededWiktorowicz and collaborators performed a massive suite of simulations made possible by donated computer time from the Universe@Home project to examine how 20 million binary systems evolve into X-ray binaries. They then determined the number and nature of the ones that could appear as ULXs to us. The authors results show that the vast majority of the observed population of ULXs can be accounted for with super-Eddington compact binaries, without needing to invoke intermediate-mass black holes.Wiktorowicz and collaborators demonstrate that in environments with short star-formation bursts, black-hole accretors are the most common ULX source in the early periods after the burst, but neutron-star accretors dominate the ULX population after a few 100 Myr. In the case of prolonged and continuous star formation, neutron-star accretors dominate ULXs if the environment is solar metallicity, whereas black-hole accretors dominate in low-metallicity environments.The authors results present very clear and testable relations between the companion and donor star evolutionary stage and the age of the system, which we will hopefully be able to use to test this model with future observations of ULXs.CitationGrzegorz Wiktorowicz et al 2017 Ap

  8. Bupivacaine administered intrathecally versus rectally in the management of intractable rectal cancer pain in palliative care

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    Zaporowska-Stachowiak I

    2014-10-01

    Full Text Available Iwona Zaporowska-Stachowiak,1,2 Grzegorz Kowalski,3 Jacek Łuczak,2 Katarzyna Kosicka,4 Aleksandra Kotlinska-Lemieszek,3 Maciej Sopata,3 Franciszek Główka4 1Chair and Department of Pharmacology, Poznan University of Medical Sciences, Poznan, Poland; 2Palliative Medicine In-patient Unit, University Hospital of Lord's Transfiguration, Poznan University of Medical Sciences, Poznan, Poland; 3Palliative Medicine Chair and Department, Poznan University of Medical Sciences, Poznan, Poland; 4Department of Physical Pharmacy and Pharmacokinetics, Poznan University of Medical Sciences, Poznan, Poland Background: Unacceptable adverse effects, contraindications to and/or ineffectiveness of World Health Organization step III "pain ladder" drugs causes needless suffering among a population of cancer patients. Successful management of severe cancer pain may require invasive treatment. However, a patient's refusal of an invasive procedure necessitates that clinicians consider alternative options. Objective: Intrathecal bupivacaine delivery as a viable treatment of intractable pain is well documented. There are no data on rectal bupivacaine use in cancer patients or in the treatment of cancer tenesmoid pain. This study aims to demonstrate that bupivacaine administered rectally could be a step in between the current treatment options for intractable cancer pain (conventional/conservative analgesia or invasive procedures, and to evaluate the effect of the mode of administration (intrathecal versus rectal on the bupivacaine plasma concentration.Cases: We present two Caucasian, elderly inpatients admitted to hospice due to intractable rectal/tenesmoid pain. The first case is a female with vulvar cancer, and malignant infiltration of the rectum/vagina. Bupivacaine was used intrathecally (0.25–0.5%, 1–2 mL every 6 hours. The second case is a female with ovarian cancer and malignant rectal infiltration. Bupivacaine was adminstered rectally (0.05–0.1%, 100 m

  9. Pulsating Star Mystery Solved

    Science.gov (United States)

    2010-11-01

    By discovering the first double star where a pulsating Cepheid variable and another star pass in front of one another, an international team of astronomers has solved a decades-old mystery. The rare alignment of the orbits of the two stars in the double star system has allowed a measurement of the Cepheid mass with unprecedented accuracy. Up to now astronomers had two incompatible theoretical predictions of Cepheid masses. The new result shows that the prediction from stellar pulsation theory is spot on, while the prediction from stellar evolution theory is at odds with the new observations. The new results, from a team led by Grzegorz Pietrzyński (Universidad de Concepción, Chile, Obserwatorium Astronomiczne Uniwersytetu Warszawskiego, Poland), appear in the 25 November 2010 edition of the journal Nature. Grzegorz Pietrzyński introduces this remarkable result: "By using the HARPS instrument on the 3.6-metre telescope at ESO's La Silla Observatory in Chile, along with other telescopes, we have measured the mass of a Cepheid with an accuracy far greater than any earlier estimates. This new result allows us to immediately see which of the two competing theories predicting the masses of Cepheids is correct." Classical Cepheid Variables, usually called just Cepheids, are unstable stars that are larger and much brighter than the Sun [1]. They expand and contract in a regular way, taking anything from a few days to months to complete the cycle. The time taken to brighten and grow fainter again is longer for stars that are more luminous and shorter for the dimmer ones. This remarkably precise relationship makes the study of Cepheids one of the most effective ways to measure the distances to nearby galaxies and from there to map out the scale of the whole Universe [2]. Unfortunately, despite their importance, Cepheids are not fully understood. Predictions of their masses derived from the theory of pulsating stars are 20-30% less than predictions from the theory of the