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Sample records for edwards md mba

  1. MD/MBA programs in the United States: evidence of a change in health care leadership.

    Science.gov (United States)

    Larson, David B; Chandler, Maria; Forman, Howard P

    2003-03-01

    Managerial sciences are playing an increasingly prominent role in the organization and delivery of health care. Despite popular media reports that a rising number of physicians are acquiring a background in this discipline through MD/MBA (medical and master of business administration) programs, no recent study has verified this. This study measured changes in the number and nature of the affiliations between management and medicine in the form of MD/MBA programs in the United States. Surveys of admission officers of 125 U.S. allopathic medical schools and of the overseers of each joint MD/MBA degree program were administered in May-October 2001. Main outcome measures included program growth, curriculum and degree requirements, application and admission requirements, and program leadership and organization. The number of MD/MBA programs grew from six to 33 between 1993 and 2001, and 17 more medical schools were considering establishing the joint-degree program. Ten, 15, and 20 programs produced 27, 42, and 61 graduates in 1999, 2000, and 2001, respectively, and over 100 students were expected to graduate per year when all 33 programs matured. Program structures and oversight indicate a spectrum of philosophies regarding the appropriate level of integration of the two degrees. MD/MBA programs apparently attempt to complement medical education with management education rather than the converse. The growth in the numbers of MD/MBA programs and participants indicates rising cooperation between medical and business schools and increasing interest in management education early in the careers of graduating physicians.

  2. The Convergence of Business and Medicine: A Study of MD/MBA Programs in the United States

    Science.gov (United States)

    Keogh, Timothy J.; Martin, William Marty

    2011-01-01

    The purpose of this paper is to identify the convergence of business and medical education and describe the curricula of MD/MBA (Medical Doctor/Master of Business Administration) programs in the US. The focus of this study is to provide a guide to dual MD/MBA programs for physicians, aspiring physicians, policy makers and healthcare organizations.…

  3. Medical Students Who Pursue a Joint MD/MBA Degree: Who Are They and Where Are They Heading?

    Science.gov (United States)

    Krupat, Edward; Dienstag, Jules L; Kester, W Carl; Finkelstein, Stan N

    2016-01-21

    Increasingly, health care is being delivered in large, complex organizations, and physicians must learn to function effectively in them. As a result, several medical and business schools have developed joint programs to train physician leaders who receive both medical degree (MD) and master of business administration (MBA) degrees. We examined several themes in relation to these programs, revolving around concerns about who is attracted to them and whether exposure to the differing cultures of medicine and business have an impact on the professional identities of their graduates as manifested in their motivations, aspirations, and careers. We addressed these issues by studying students in the joint MD/MBA program at Harvard Medical School (HMS) and Harvard Business School (HBS). Our data came from several internal sources and a survey of all students enrolled in the joint program in spring 2013. We found relatively few differences between joint program students and equivalent cohorts of HMS students in terms of personal characteristics, preadmission performance, and performance at HMS and HBS. Contrary to the concerns that such programs may draw students away from medicine, the vast majority embraced careers involving extensive postgraduate medical training, with long-term plans that leveraged their new perspectives and skills to improve health care delivery. © The Author(s) 2016.

  4. MD-11 PCA - First Landing at Edwards

    Science.gov (United States)

    1995-01-01

    This McDonnell Douglas MD-11 approaches the first landing ever of a transport aircraft under engine power only on Aug. 29, 1995, at NASA's Dryden Flight Research Center, Edwards, California. The milestone flight, flown by NASA research pilot and former astronaut Gordon Fullerton, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when it normal control surfaces are disabled. The Propulsion-Controlled Aircraft (PCA) system uses standard autopilot controls already present in the cockpit, together with the new programming in the aircraft's flight control computers. The PCA concept is simple--for pitch control, the program increases thrust to climb and reduces thrust to descend. To turn right, the autopilot increases the left engine thrust while decreasing the right engine thrust. The initial Propulsion-Controlled Aircraft studies by NASA were carried out at Dryden with a modified twin-engine F-15 research aircraft.

  5. MD/MBA Students: An Analysis of Medical Student Career Choice

    Directory of Open Access Journals (Sweden)

    Windsor Westbrook Sherrill, Ph.D., MBA

    2004-01-01

    Full Text Available Background: An increasing number of medical schools are offering dual degree MD/MBA programs. Career choices and factors influencing students to enter these programs provide an indicator of the roles in which dual degree students will serve in health care as well as the future of dual degree programs. Purpose: Using career choice theory as a conceptual framework, career goals and factors influencing decisions to enter dual degree programs were assessed among dual degree medical students. Methods: Students enrolled at dual degree programs at six medical schools were surveyed and interviewed. A control group of traditional medical students was also surveyed. Results: Factors influencing students to seek both medical and business training are varied but are often related to a desire for leadership opportunities, concerns about change in medicine and job security and personal career goals. Most students expect to combine clinical and administrative roles. Conclusions: Students entering these programs do so for a variety of reasons and plan diverse careers. These findings can provide guidance for program development and recruitment for dual degree medical education programs

  6. MD/MBA Students: An Analysis of Medical Student Career Choice

    Directory of Open Access Journals (Sweden)

    Windsor Westbrook Sherrill, Ph.D., MBA

    2004-01-01

    Full Text Available Background: An increasing number of medical schools are offering dual degree MD/MBA programs. Career choices and factors influencing students to enter these programs provide an indicator of the roles in which dual degree students will serve in health care as well as the future of dual degree programs. Purpose: Using career choice theory as a conceptual framework, career goals and factors influencing decisions to enter dual degree programs were assessed among dual degree medical students. Methods: Students enrolled at dual degree programs at six medical schools were surveyed and interviewed. A control group of traditional medical students was also surveyed. Results: Factors influencing students to seek both medical and business training are varied but are often related to a desire for leadership opportunities, concerns about change in medicine and job security and personal career goals. Most students expect to combine clinical and administrative roles. Conclusions: Students entering these programs do so for a variety of reasons and plan diverse careers. These findings can provide guidance for program development and recruitment for dual degree medical education program

  7. MD/MBA Students: An Analysis of Medical Student Career Choice.

    Science.gov (United States)

    Sherrill, Windsor Westbrook

    2004-12-01

    An increasing number of medical schools are offering dual degree MD/MBA programs. Career choices and factors influencing students to enter these programs provide an indicator of the roles in which dual degree students will serve in health care as well as the future of dual degree programs. Using career choice theory as a conceptual framework, career goals and factors influencing decisions to enter dual degree programs were assessed among dual degree medical students. Students enrolled at dual degree programs at six medical schools were surveyed and interviewed. A control group of traditional medical students was also surveyed. Factors influencing students to seek both medical and business training are varied but are often related to a desire for leadership opportunities, concerns about change in medicine and job security and personal career goals. Most students expect to combine clinical and administrative roles. Students entering these programs do so for a variety of reasons and plan diverse careers. These findings can provide guidance for program development and recruitment for dual degree medical education programs.

  8. Payer Perspectives on PCSK9 Inhibitors: A Conversation with Stephen Gorshow, MD, and James T. Kenney, RPh, MBA.

    Science.gov (United States)

    Mehr, Stanton R

    2016-02-01

    The new proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors can have significant budget effects, depending on the breadth of the US Food and Drug Administration (FDA)'s approved labeling. American Health & Drug Benefits asked Stephen Gorshow, MD, Regional Medical Director, UnitedHealthcare, and James T. Kenney, RPh, MBA, Manager, Specialty and Pharmacy Contracts, Harvard Pilgrim Health Care, to participate in a teleconference to better understand how payers are approaching the management of these agents.

  9. Physicians with MBA degrees: change agents for healthcare improvement.

    Science.gov (United States)

    Lazarus, Arthur

    2010-01-01

    Increasingly, physicians gravitating toward the fields of quality improvement and healthcare management are seeking MBA degrees to supplement their medical training. Approximately half of all U.S. medical schools offer combined MD-MBA degrees, and numerous executive MBA programs exist for physicians in practice. Physicians who enter management are considered change agents for healthcare improvement, yet they receive little support and encouragement from their medical teachers and practicing colleagues. This situation can be rectified by placing greater value on the role of business-trained physicians and subsidizing their tuition for business school.

  10. Leadership training for radiologists: a survey of opportunities and participants in MBA and MPH programs by medical students, residents, and current chairpersons.

    Science.gov (United States)

    Baker, Stephen; Daginawala, Naznin

    2011-08-01

    The aim of this study was to determine opportunities for students and trainees to obtain an MPH or MBA degree during either medical school or radiology residency and to determine the prevalence of such degree possession by chairpersons in radiology. All allopathic medical schools in the United States were surveyed to chart the number of MD/MPH and MD/MBA degree programs available to students. Program directors were contacted to assess the number of MPH or MBA courses of study administratively related to their residencies. Also, an e-mail survey was sent to all members of the Society of Chairs of Academic Radiology Departments inquiring whether each chairperson had earned an additional degree. Currently, 81 allopathic medical schools in the United States offer MD/MPH degrees, and 52 offer MD/MBA degrees. Six residencies provide access to MPH programs, and 3 residencies provide the opportunity to pursue an MBA in conjunction with residency. Of these, only 1 MPH program and no MBA programs had trainees enrolled at present. Twenty-six percent of the chairpersons surveyed possessed advanced degrees other than MDs. There has been rapid growth in the number of MD/MPH and MD/MBA programs available to medical students. However, there is a scarcity of similar programs accessible to trainees during or just after residency training. To assist motivated radiologists interested in leading our profession, opportunities should expand both in formal degree-granting programs and through certificate-sanctioned course series to address relevant issues of leadership and management pertinent to our specialty. Copyright © 2011 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  11. The role of MD and MBA training in the professional development of a physician: a survey of 30 years of graduates from the Wharton Health Care Management Program.

    Science.gov (United States)

    Patel, Mitesh S; Arora, Vishal; Patel, Mamta S; Kinney, June M; Pauly, Mark V; Asch, David A

    2014-09-01

    The number of medical schools offering MD and MBA training has increased fivefold in the last two decades. The authors evaluated graduates' perceptions of the role of such training on their career and professional development. In 2011, the authors surveyed physician graduates from the Wharton School MBA Program in Heath Care Management at the University of Pennsylvania from 1981 to 2010. Survey responses were analyzed and evaluated using grounded theory. Among 247 eligible graduates, 59.9% (148/247) completed the questionnaire and 89.9% (133/148) of them provided free-text responses. Approximately 85.1% (126/148) of respondents were male and 79.7% (118/148) entered residency training; however, both rates declined slightly over time. Among respondents within their first decade after graduation, 46.2% (24/52) reported clinical practice as their primary work sector compared with 39.5% (15/38) among respondents 11 to 20 years after graduation and 19.2% (5/26) of respondents 21 to 30 years after graduation. Overall, graduates reported mostly positive attitudes and often noted the benefits of career acceleration, professional flexibility, and credibility in multidisciplinary domains. The few negative remarks were focused on the opportunity cost of time and how peers in one discipline may negatively perceive the role of the other discipline's degree. Graduates with an MD and MBA report mostly positive attitudes towards their training, and many are pursuing leadership and primarily nonclinical roles later in their careers. These findings reveal new insights for policies affecting physician workforce. Further study is necessary to evaluate whether similar trends exist more broadly.

  12. The rudiments of an Internet-based health plan for consumers: an interview with John Danaher, MD, MBA. Interview by Richard L. Reece.

    Science.gov (United States)

    Danaher, J

    2000-01-01

    Richard L. Reece, MD, interviewed John Danaher, MD, MBA, on August 16, 2000, to discuss how his new company is preparing for the perfect storm--the looming convergence of demanding consumers, defined contributions, and Internet-based health plans. He describes how his firm is putting financial and clinical tools in the hands of consumers and physicians, so consumers can be more enlightened in their health care choices. Danaher says, "We're not about buying goods and services online. We are transforming the way consumers buy health care and seek insurance. We're trying to be a 401 k where people get on, knowing their risk profile and return horizons. We aim to motivate consumers to be proactive in making health care choices. How do we make consumers responsible and motivated enough to take control of managing their health care costs? How well we articulate this call to consumer action will be the key to our success."

  13. Mary Edwards Walker, M.D.: a feminist physician a century ahead of her time.

    Science.gov (United States)

    Spiegel, A D; Suskind, P B

    1996-06-01

    In her teens, Mary Edwards Walker already wore the "bloomer" outfit began to campaign for reforming the "unhygienic" clothing of women. Assertively, she attended medical school and earned her M.D. degree. Due to prejudice, her practice did not flourish and she moved to Washington to offer her medical services to the Union as the Civil War began. Rebuffed by the male medical bureaucrats, she volunteered her services anyway. Eventually, she was awarded the Congressional Medal of Honor, the only women to ever gain such distinction. After the war, Walker became a journalist, an author of two sensational books, a political lobbyist, a suffrage campaigner, a professional and public lecturer, an ardent dress reformer, a peace activist, a Utopianist and a women's right advocate. Light-years ahead of her times, Dr. Walker was an intelligent, independent, irrepressible and indefatigable proponent for a host of worthy causes.

  14. The Impact of MBA Programme Attributes on Post-MBA Salaries

    OpenAIRE

    Elliott, Caroline; Soo, Kwok Tong

    2016-01-01

    This paper explores the impact of various MBA programme attributes on the average post-MBA salary of graduates, contributing to the literature on the returns to an MBA degree, which to date has instead focused predominantly on the impact of individual student traits. The analysis uses a new panel dataset, comprising MBA programmes from across the world. Results indicate that pre-MBA salary and quality rank of programme are key determinants of post-MBA salary.

  15. To MBA or Not to MBA

    Science.gov (United States)

    Baruch, Yehuda

    2009-01-01

    Purpose: The purpose of this paper is to critically reflect on the value of the MBA--a Master in Business Administration, considered the flagship of business and management education. The author aims to bridge the gap in the understanding of the possible added value of the MBA. Design/methodology/approach: This conceptual paper is enriched by…

  16. The Impact of MBA Programme Attributes on Post-MBA Salaries

    Science.gov (United States)

    Elliott, Caroline; Soo, Kwok Tong

    2016-01-01

    This paper explores the impact of various Master of Business Administration (MBA) programme attributes on the average post-MBA salary of graduates, contributing to the literature on the returns to an MBA degree, which to date has instead focused predominantly on the impact of individual student traits. The analysis uses a new panel dataset,…

  17. Graduates: Perceptions of MBA Value

    Science.gov (United States)

    Bledsoe, Maynard T.; Oatsvall, Rebecca

    2009-01-01

    MBA worth--who decides? Much of the current assessment comes from market driven and/or institutional perspectives. This research examines responses from Meredith College MBA graduates to determine their perceptions of the worth and value of their MBA experience.

  18. Important Characteristics in an MBA Program: The Perceptions of Online MBA Students

    Science.gov (United States)

    Rydzewski, Danielle N.; Eastman, Jacqueline K.; Bocchi, Joseph

    2010-01-01

    This study examines characteristics important to online MBA students and alumni. The study looks at what characteristics are important in an online MBA Program and if the level of importance of these characteristics varies by demographic variables. The study focuses on availability, program quality, program length, cost, and courses in the…

  19. Covalently linked multimers of gold nanoclusters Au102(p-MBA)44 and Au∼250(p-MBA)n.

    Science.gov (United States)

    Lahtinen, Tanja; Hulkko, Eero; Sokołowska, Karolina; Tero, Tiia-Riikka; Saarnio, Ville; Lindgren, Johan; Pettersson, Mika; Häkkinen, Hannu; Lehtovaara, Lauri

    2016-11-10

    We present the synthesis, separation, and characterization of covalently-bound multimers of para-mercaptobenzoic acid (p-MBA) protected gold nanoclusters. The multimers were synthesized by performing a ligand-exchange reaction of a pre-characterized Au 102 (p-MBA) 44 nanocluster with biphenyl-4,4'-dithiol (BPDT). The reaction products were separated using gel electrophoresis yielding several distinct bands. The bands were analyzed by transmission electron microscopy (TEM) revealing monomer, dimer, and trimer fractions of the nanocluster. TEM analysis of dimers in combination with molecular dynamics simulations suggest that the nanoclusters are covalently bound via a disulfide bridge between BPDT molecules. The linking chemistry is not specific to Au 102 (p-MBA) 44 . The same approach yields multimers also for a larger monodisperse p-MBA-protected cluster of approximately 250 gold atoms, Au ∼250 (p-MBA) n . While the Au 102 (p-MBA) 44 is not plasmonic, the Au ∼250 (p-MBA) n nanocluster supports localized surface plasmon resonance (LSPR) at 530 nm. Multimers of the Au ∼250 (p-MBA) n exhibit additional transitions in their UV-vis spectrum at 630 nm and 810 nm, indicating the presence of hybridized LSPR modes. Well-defined structures and relatively small sizes make these systems excellent candidates for connecting ab initio theoretical studies and experimental quantum plasmonics. Moreover, our work opens new possibilities in the controlled synthesis of advanced monodisperse nanocluster superstructures.

  20. Traditional Master of Business Administration (MBA) versus the MBA with Specialization: A Disconnection between What Business Schools Offer and What Employers Seek

    Science.gov (United States)

    Gupta, Pola B.; Saunders, Paula M.; Smith, Jeremy

    2007-01-01

    A trend in master of business administration (MBA) programs has been to offer more specializations beyond the traditional broad MBA. In this article, the authors explore the recruitment practices of business and the curricula of MBA programs comparing general MBA degrees with MBA degrees with specialization. The authors empirically examine whether…

  1. Effects of MBA Training in Managerial Success.

    Science.gov (United States)

    Orpen, Christopher

    1982-01-01

    This study compares the effects of MBA versus non-MBA training on job success. Results were determined by answers to a questionnaire concerning salary, position in the company hierarchy, and job satisfaction. Results show that having an MBA helped with salary and position, but not necessarily with job satisfaction. (CT)

  2. The Purpose of the MBA Degree: The Opportunity for a Confucian MBA to Overcome Neoliberalism

    Science.gov (United States)

    Shaw, Robert Keith

    2017-01-01

    This paper is a prolegomena to discussions about a differentiated Confucian MBA curriculum. We draw upon Kant's notion of individual autonomy and our observations of practice to argue that there are three models extant for the MBA degree. One of these, that which emphasizes leadership, holds considerable potential if it develops in the context of…

  3. Delivering an MBA Management Consulting Experience

    Science.gov (United States)

    LeMaire, Ryan; Fisher, Kirk; Watson, Edward F., III

    2017-01-01

    This article reports on an innovative MBA elective consulting course that attempts to address how to better prepare inexperienced MBA students for a competitive job market. This article is a best practice paper designed to provide insights and encouragement to educators.

  4. Today's MBA: A Lot to Learn.

    Science.gov (United States)

    Roth, William F., Jr.

    1989-01-01

    Cultural skills and a systems perspective are critical to the success of Masters of Business Administration (MBA) graduates. Many employers recommend that students take a job before continuing graduate study; they also advocate the teaching of cultural skills and the development ethic in MBA programs. (SK)

  5. Assessing Emphasis Gaps among MBA Alumni: A Model Framework

    Science.gov (United States)

    Van Auken, Stuart; Chrysler, Earl; Wells, Ludmilla Gricenko

    2016-01-01

    Purpose: This paper aims to focus on Master of Business Administration (MBA) alumni and their ability to provide institution-specific insights into MBA program delivery. Given desired MBA positioning dimensions, a case exemplar is used to reveal gaps between "should have" program emphases and "actual" emphases. Departures from…

  6. Exploring the Value of MBA Degrees: Students' Experiences in Full-Time, Part-Time, and Executive MBA Programs

    Science.gov (United States)

    Bruce, Grady D.

    2010-01-01

    Critics of the overall value of the MBA have not systematically considered the attitudes of MBA students about the value of their degree. The author used data from a large sample of graduates (N = 16,268) to do so, and to explore predictors of overall degree value. The author developed separate regression models for full-time, part-time, and…

  7. Measuring the Economic Value of Pre-MBA Work Experience

    Science.gov (United States)

    Yeaple, Ronald N.; Johnston, Mark W.; Whittingham, Keith L.

    2010-01-01

    Pre-MBA work experience is required for admission to many graduate schools of business. In the present study, MBA graduates with a wide range of pre-MBA work experience were surveyed to assess the economic value of such work experience. No evidence was found of a systematic financial advantage to students from working for several years before…

  8. Technology and optical characterization of luminophore coordination compounds Eu(o-MBA)3Phen and NC PEPC/Eu(o-MBA)3Phen

    Science.gov (United States)

    Bordian, Olga; Verlan, Victor; Culeac, Ion; Iovu, Mihail; Zubareva, Vera

    2016-12-01

    Were obtained a new nanocomposite (NC) based on poly N-epoxy prolyl carbazol (PEPC) and the coordination compound luminophore Eu(o-MBA)3Phen, where o-MBA is o- methylbenzoic acid and Phen - phenanthroline. Nanocrystals of Eu(o-MBA)3Phen with the dimensions 50 nm were uniformly incorporated into the PEPC polymer matrix with various concentrations. The absorption spectra of coordination compounds and thin layers of NC PEPC/Eu(o-MBA)3Phen revealed 1 intensive absorption bands at 2.02 eV. Photoluminescence (PL) spectra showed an intense red luminescence at 578 - 699 nm, which is assigned to the transitions 4D0->7Fi (i= 0,1,2 3 4) in the 4f-shell of the Eu3+ ion.

  9. Exploring the branding and marketing communications strategies of Nottingham MBA in China

    OpenAIRE

    Jiang, Baitao

    2011-01-01

    Background The MBA education becomes more popular nowadays. The competition amongst MBA programmes in different countries is being increasingly fierce. In order to diversifies the source of students and expend the market, MBA programmes pursue to entry overseas markets. As a result, the competition of the MBA market is changing from nationally to internationally. MBA programme managers start to apply marketing knowledge to competing for the students globally. As a high level and expensive,...

  10. Internationalization of China's MBA Education: Failing to Walk the Talk?

    Science.gov (United States)

    Ma, Shaozhuang; Trigo, Virginia

    2011-01-01

    This article presents an overview of the internationalization of MBA education in Mainland China, exposes the main challenges this education is facing and proposes strategies to overcome them. Results reveal two main findings: 1) Chinese MBA educators show a growing interest and awareness in the internationalization of their MBA education, but…

  11. Human Capital Augmentation versus the Signaling Value of MBA Education

    Science.gov (United States)

    Hussey, Andrew

    2012-01-01

    Panel data on MBA graduates is used in an attempt to empirically distinguish between human capital and signaling models of education. The existence of employment observations prior to MBA enrollment allows for the control of unobserved ability or selection into MBA programs (through the use of individual fixed effects). In addition, variation in…

  12. Empirical Investigation of Predictors of Success in an MBA Programme

    Science.gov (United States)

    Gupta, Atul; Turek, Joseph

    2015-01-01

    Purpose: The twofold purpose of this study was to determine if selected variables were predictors of: student performance in the MBA programme; and student performance on the MBA MFT exam. Design/methodology/approach: This study focuses on MBA graduates at a US university who have successfully completed the entire programme requirements. Real…

  13. Attitudes and Perceptions of Dual PharmD/MBA Degree Program Students.

    Science.gov (United States)

    Jacobs, David M; Daly, Christopher J; Tierney, Sarah-Elizabeth L; O'Brien, Erin; Fiebelkorn, Karl D

    2017-05-01

    Objectives. To understand pharmacy students' reasons for pursuing a dual PharmD/MBA degree and their perceptions of the impact a dual degree will have on their careers. Methods. This was a cross-sectional survey of registered students in the University at Buffalo PharmD/MBA program. An electronic survey was developed through collaboration with the UB School of Management and administered in January 2015. Results. A total of 23/24 (96% response rate) students who were enrolled in the PharmD/MBA curriculum responded to the survey. Respondents identified employment opportunities following graduation and career advancement as the most influential determinants in deciding to pursue an MBA degree. All respondents (100%) felt the job marketplace for pharmacy graduates is becoming increasingly difficult, 96% believe they will earn a higher midpoint salary with a PharmD/MBA, and 82% would recommend a PharmD/MBA to first year pharmacy students. Conclusion. Students are increasingly perceptive of the challenges in the current job marketplace and are taking advantage of a dual PharmD/MBA degree.

  14. Edward Settle | NREL

    Science.gov (United States)

    Settle Photo of Edward Settle Edward Settle Senior Project Leader - Financing Edward.Settle energy microgrid project. He has more than 25 years of experience providing leadership and advisory projects. Research Interests Energy project finance Energy project tax matters Microgrids Resiliency

  15. Cross-Disciplinary Ethics Education in MBA Programs

    DEFF Research Database (Denmark)

    Rasche, Andreas; Gilbert, Dirk Ulrich; Schedel, Ingo

    2013-01-01

    This research-based essay offers a cross-disciplinary examination of ethics education in MBA programs. Based on data underlying the Beyond Grey Pinstripes (BGP) survey we find: that business schools doubled the number of ethics-related courses in different disciplines between 2005 and 2009......: business schools increasingly risk creating a gap between their upbeat rhetoric around ethics education and their actual MBA curriculum. Such decoupling is likely to emerge because schools face a tension between increasing institutional pressures to legitimize their MBA programs and internal impediments...... to fully integrate ethics into the curriculum. We suggest that more effective ethics education requires structural changes to the curriculum, in particular more mandatory ethics courses and a stronger integration of ethics-related debates into disciplines like finance and accounting....

  16. Cross-Disciplinary Ethics Education in MBA Programs

    DEFF Research Database (Denmark)

    Rasche, Andreas; Gilbert, Dirk Ulrich; Schedel, Ingo

    This research-based essay offers a cross-disciplinary examination of ethics education in MBA programs. Based on data underlying the Beyond Grey Pinstripes (BGP) survey we find: that business schools doubled the number of ethics-related courses in different disciplines between 2005 and 2009......: business schools increasingly risk creating a gap between their upbeat rhetoric around ethics education and their actual MBA curriculum. Such decoupling is likely to emerge because schools face a tension between increasing institutional pressures to legitimize their MBA programs and internal impediments...... to fully integrate ethics into the curriculum. We suggest that more effective ethics education requires structural changes to the curriculum, in particular more mandatory ethics courses and a stronger integration of ethics-related debates into disciplines like finance and accounting....

  17. What Do Online MBA Professors Have to Say about Online Teaching

    Science.gov (United States)

    Liu, Shijuan; Kim, Kyong-Jee; Bonk, Curtis J.; Magjuka, Richard

    2007-01-01

    Online MBA programs have grown exponentially in recent years. Yet, the prevailing literature indicates that research on online MBA education remains extremely limited. This article summarizes 28 instructor interviews from those teaching online courses in an online MBA program at a Midwestern public university. Instructors were interviewed…

  18. Designing a Holistic Experiential MBA Course for 21st Century Leaders

    Science.gov (United States)

    Dixon, Deirdre

    2014-01-01

    With the plethora of MBA leadership courses, schools are examining ways to differentiate their programs and to provide tangible learning outcomes. MBA graduates want the knowledge skills and ability to make them successful in their chosen fields of endeavor. This paper outlines one holistic experiential MBA leadership course that challenges the…

  19. The Regional MBA: Distinct Segments, Wants, and Needs

    Science.gov (United States)

    Passyn, Kirsten; Diriker, Memo

    2011-01-01

    MBA Programs in top-tier school differ greatly from those in regional schools. A survey that aimed at assessing segmentation, pedagogy, and satisfaction in regional MBA programs was developed and administered in three universities of the Mid Atlantic, Midwest, and Southern regions. The results show four clearly distinguished segments that…

  20. Knowledge and Skills Transfer between MBA and Workplace

    Science.gov (United States)

    Prince, Melvin; Burns, David; Lu, Xinyi; Winsor, Robert

    2015-01-01

    Purpose: This paper aims to use goal-setting theory to explain the transfer of knowledge and skills between master of business administration (MBA) and the workplace. Design/methodology/approach: Data were obtained by an online survey of MBA students enrolled in at four US graduate business schools. These were a public and private institution in…

  1. Adding Value: Open Online Learning and the MBA

    Science.gov (United States)

    Fitzgerald, Rachel; Anderson, Maggie; Thompson, Ross

    2015-01-01

    Evidence suggests that MOOCs are being used as a strategic tool to explore alternative models of course delivery (Allen & Seaman, 2013) and this paper shares insight into an example of such innovation for Business School Education. Gateway MBA draws on examples of open learning worldwide to create a MOOC to extend the MBA distance learning…

  2. Academic Performance in MBA Programs: Do Prerequisites Really Matter?

    Science.gov (United States)

    Christensen, Donald Gene; Nance, William R.; White, Darin W.

    2012-01-01

    Many researchers have examined criteria used in Master of Business Administration (MBA) admissions decisions. However, prior research has not examined predictive ability of undergraduate prerequisite courses in core business disciplines. The authors investigated whether undergraduate prerequisite courses predicted MBA success by analyzing the…

  3. The Gender Difference: Validity of Standardized Admission Tests in Predicting MBA Performance.

    Science.gov (United States)

    Hancock, Terence

    1999-01-01

    Of 120 female and 149 male master of business administration (MBA) students, women performed significantly less well on the Graduate Management Admission Test (GMAT). There were no differences in overall MBA grade point average, indicating no strong correlation between the GMAT and MBA performance. (SK)

  4. Do Specialized MBA Programs Cultivate Alumni Relationships and Donations?

    Science.gov (United States)

    Johnson, Jennifer Wiggins; Thomas, Veronica; Peck, Joann

    2010-01-01

    A recent trend among universities shifts from traditional MBA programs to specialized MBA offerings. Specialized programs are believed to cultivate stronger relationships with students, which lead to stronger alumni relationships and increased donations. This research tests this empirically by examining relationship perceptions and donation…

  5. Post-MBA Industry Shifts: An Investigation of Career, Educational and Demographic Factors

    Science.gov (United States)

    Hwang, Alvin; Bento, Regina; Arbaugh, J. B.

    2011-01-01

    Purpose: The purpose of this study is to examine factors that predict industry-level career change among MBA graduates. Design/methodology/approach: The study analyzed longitudinal data from the Management Education Research Institute (MERI)'s Global MBA Graduate Survey Dataset and MBA Alumni Perspectives Survey Datasets, using principal component…

  6. MBA Curriculum: The Role of an Introductory "Toolkit" Course

    Science.gov (United States)

    Carson, Charles M.; Jones, Steven T.; Dance, Jeffrey W.; Finch, James H.; Holloway, Betsy B.; Reburn, James P.; Belski, William H.

    2013-01-01

    Graduate business students enter MBA programs intent on completing their degrees to open new professional opportunities and enhance their prospective career earnings potential. Because of the diversity of backgrounds new students bring into their MBA programs, large variations exist among their academic and professional backgrounds. Curriculums…

  7. Attitudial Belief on Adoption of E-MBA Program in Malaysia

    Directory of Open Access Journals (Sweden)

    Muhammad Hasmi Abu Hassan ASAARI

    2005-04-01

    Full Text Available Attitudial Belief on Adoption of E-MBA Program in Malaysia Noornina DAHLANT. RAMAYAHRamzah MAHMODNoorliza KARIAMuhammad Hasmi Abu Hassan ASAARIUniversiti Sains Malaysia PENANG , MALAYSIA ABSTRACT E-learning describes the use of information communications technology for learning beyond the boundaries of the conventional classroom. The objective of this paper is to determine what are the factors that are significant in explaining intention towards e-learning, particularly e-MBA adoption in Malaysia . Results indicated that trialability and image were significant influencing behavior intention towards e-MBA adoption.

  8. MD-11 PCA - Research flight team photo

    Science.gov (United States)

    1995-01-01

    On Aug. 30, 1995, a the McDonnell Douglas MD-11 transport aircraft landed equipped with a computer-assisted engine control system that has the potential to increase flight safety. In landings at NASA Dryden Flight Research Center, Edwards, California, on August 29 and 30, the aircraft demonstrated software used in the aircraft's flight control computer that essentially landed the MD-11 without a need for the pilot to manipulate the flight controls significantly. In partnership with McDonnell Douglas Aerospace (MDA), with Pratt & Whitney and Honeywell helping to design the software, NASA developed this propulsion-controlled aircraft (PCA) system following a series of incidents in which hydraulic failures resulted in the loss of flight controls. This new system enables a pilot to operate and land the aircraft safely when its normal, hydraulically-activated control surfaces are disabled. This August 29, 1995, photo shows the MD-11 team. Back row, left to right: Tim Dingen, MDA pilot; John Miller, MD-11 Chief pilot (MDA); Wayne Anselmo, MD-11 Flight Test Engineer (MDA); Gordon Fullerton, PCA Project pilot; Bill Burcham, PCA Chief Engineer; Rudey Duran, PCA Controls Engineer (MDA); John Feather, PCA Controls Engineer (MDA); Daryl Townsend, Crew Chief; Henry Hernandez, aircraft mechanic; Bob Baron, PCA Project Manager; Don Hermann, aircraft mechanic; Jerry Cousins, aircraft mechanic; Eric Petersen, PCA Manager (Honeywell); Trindel Maine, PCA Data Engineer; Jeff Kahler, PCA Software Engineer (Honeywell); Steve Goldthorpe, PCA Controls Engineer (MDA). Front row, left to right: Teresa Hass, Senior Project Management Analyst; Hollie Allingham (Aguilera), Senior Project Management Analyst; Taher Zeglum, PCA Data Engineer (MDA); Drew Pappas, PCA Project Manager (MDA); John Burken, PCA Control Engineer.

  9. A Conjoint Analysis to Determine the Preferences for Some Selected MBA Programs

    Directory of Open Access Journals (Sweden)

    İlknur Özmen

    2006-05-01

    Full Text Available This paper reviews the Conjoint Analysis Method (CAM, which is a multivariate marketing research technique used to determine consumer behaviours and preferences for products or services. One aim of this study is to demonstrate that the CAM can be used in “Service Sector” as well as in “Product Sector” and the other aim is to utilize CBC Sawtooth Software Program, which is a special program for CAM. A usage of CBC Sawtooth Software Program is demonstrated in the analysis of Management Business Administration (MBA program preferences of Başkent University students. This study includes those MBA programs that require substantial tuition and fee payments. According to the results of the study, “University Name” plays the most important role in MBA preferences. The Conjoint Analysis found that, most preferred university is the Boğaziçi University and the most preferred type of MBA program is the “Executive MBA Program”. Another important finding is that “Higher Tuition and Fees” makes the MBA less attractive.. Este trabajo examina el método de análisis conjunto (CAM, que es una técnica multivariante de investigación de mercados utilizada para determinar los comportamientos y preferencias del consumidor por productos o servicios. Un objetivo de este estudio es demostrar que el CAM puede ser aplicado en el "sector servicios" al igual que en el "sector de producción". El otro objetivo principal es utilizar programa informático CBC de Sawtooth, que es un programa especial para CAM. El CBC de Sawtooth se aplica a las preferencias de estudiantes por los programas de Administración y Dirección de Empresas de (MBA de la universidad de Baskent. Este estudio incluye sólo los programas de MBA que requieren una cuota de matrícula cuantiosa y pago de honorarios. Los resultados del estudio muestran que la variable "nombre de la universidad" es la más importante en las preferencias que los alumnos tienen por los MBA. El An

  10. Research on the Internationalization and the Localization of China's MBA Education

    Science.gov (United States)

    Lin, Jie; Ma, Haiyong

    2012-01-01

    This article started with a brief review of the history and current situation of Chinese MBA education and its internationalization and localization. Then, the author presented the opportunities faced of China's MBA education. Furthermore, the challenges faced by Chinese MBA education in the globalization process together with their implications…

  11. A Case Study of the MBA Market in Western Australia.

    Science.gov (United States)

    Everett, James E.; Armstrong, Robert W.

    1993-01-01

    The Western Australia market for master's-level business administration education (MBA) is examined, particularly relating to the University of Western Australia. An overview of current Australian MBA market conditions is given; and the history, competitive environment, structure, admission policy, tuition, and student financial aid of the…

  12. A preliminary model to identify low-risk MBA applicants

    Directory of Open Access Journals (Sweden)

    CA Bisschoff

    2014-08-01

    The reliability of the discriminant function rates favourably with 71% (MBA in 3 years, 62% (MBA in 4 years and 83% (dropping out of the programme being categorised correctly by the respective discriminant functions. Being a preliminary model, its predictive capabilities need to be verified in practice before it can  be implemented as tool to render assistance in MBA admissions.  The value of this research lies  in the fact that it constitutes a model that could be employed and improved as a predictive tool in an environment where very limited predictive tools exist.  Therefore, although it is by no means a tried and tested model, it sets the scene by supplying a scientific base from which incremental improvements could result.

  13. Minimum emittance in TBA and MBA lattices

    Science.gov (United States)

    Xu, Gang; Peng, Yue-Mei

    2015-03-01

    For reaching a small emittance in a modern light source, triple bend achromats (TBA), theoretical minimum emittance (TME) and even multiple bend achromats (MBA) have been considered. This paper derived the necessary condition for achieving minimum emittance in TBA and MBA theoretically, where the bending angle of inner dipoles has a factor of 31/3 bigger than that of the outer dipoles. Here, we also calculated the conditions attaining the minimum emittance of TBA related to phase advance in some special cases with a pure mathematics method. These results may give some directions on lattice design.

  14. Minimum emittance in TBA and MBA lattices

    International Nuclear Information System (INIS)

    Xu Gang; Peng Yuemei

    2015-01-01

    For reaching a small emittance in a modern light source, triple bend achromats (TBA), theoretical minimum emittance (TME) and even multiple bend achromats (MBA) have been considered. This paper derived the necessary condition for achieving minimum emittance in TBA and MBA theoretically, where the bending angle of inner dipoles has a factor of 3 1/3 bigger than that of the outer dipoles. Here, we also calculated the conditions attaining the minimum emittance of TBA related to phase advance in some special cases with a pure mathematics method. These results may give some directions on lattice design. (authors)

  15. Homophobia in Marlowe’s Edward II Homophobia in Marlowe’s Edward II

    Directory of Open Access Journals (Sweden)

    Gelson Peres de Silva

    2008-04-01

    Full Text Available Drawing on queer theory, this essay demonstrates how homophobia motivates the plot of usurpation in Edward II, by Chistopher Marlowe (1564-1593, a play in which complex power relations can be verified. The main characters, King Edward II, Pierce of Gaveston, Mortimer Junior, Mortimer Senior and Queen Isabella, together with the nobles and the clerics, interact in a world of fierce political dispute. Power relations are at the core of the play and involve, on the one hand, the characters who envy and dispute Edward II’s royal power. On the other hand, the king suffers the effects of the power of his own homosexual drive and affective ties with Gaveston. Drawing on queer theory, this essay demonstrates how homophobia motivates the plot of usurpation in Edward II, by Chistopher Marlowe (1564-1593, a play in which complex power relations can be verified. The main characters, King Edward II, Pierce of Gaveston, Mortimer Junior, Mortimer Senior and Queen Isabella, together with the nobles and the clerics, interact in a world of fierce political dispute. Power relations are at the core of the play and involve, on the one hand, the characters who envy and dispute Edward II’s royal power. On the other hand, the king suffers the effects of the power of his own homosexual drive and affective ties with Gaveston.

  16. Examining the Perceptions of Brand Images Regarding Competing MBA Programs

    Science.gov (United States)

    Hinds, Timothee; Falgoust, Dexter; Thomas, Kerry, Jr.; Budden, Michael C.

    2010-01-01

    In today's economic environment, it is crucial to create a strong, consistent brand image within a graduate business program. This study examines the perceptions that students at Southeastern Louisiana University hold about its MBA program and the MBA programs of its main competitors. A focus group was conducted to identify competitors and factors…

  17. Library Services Online: Introducing Library Services for Online MBA Classes

    Science.gov (United States)

    Slavin, Laura C.

    2015-01-01

    In this article, a librarian at Lincoln Memorial University creates library services for an MBA program offered entirely online that is in the early stages of development. The library services include a subject guide and 4 tutorials that will be added to the MBA online orientation. Other services include offering online office hours and…

  18. Investigating MBA Degrees Earned by Women: A Decade of Change

    Science.gov (United States)

    McConnell, Cheryl; Rush, Douglas; Gartland, Myles

    2016-01-01

    The authors examined master of business administration (MBA) degrees earned by women at U.S. higher education institutions at three specific years spanning a decade: 2003, 2008, and 2013 to determine whether there was a significant difference in the percentage of MBA degrees earned by women based on the independent variables of institutional type,…

  19. MBA acceptance test procedures, software Version 1.4

    International Nuclear Information System (INIS)

    Mullaney, J.E.; Russell, V.K.

    1994-01-01

    The Mass Balance Program (MBA) is an adjunct to the Materials Accounting database system, Version 3.4. MBA was written to equip the personnel performing K-Basin encapsulation tasks with a conservative estimate of accumulated sludge during the processing of canisters into and out of the chute. The K Basins Materials Balance programs had some minor improvements made to it to feedback the chute processing status to the operator better. This ATP describes how the code was to be tested to verify its correctness

  20. Should I get a Master of Business Administration? The anesthesiologist with education training: training options and professional opportunities.

    Science.gov (United States)

    Desai, Arjun M; Trillo, Raul A; Macario, Alex

    2009-04-01

    Many physicians want to know whether they should get a Master of Business Administration (MBA), what type of program is best, and what career paths exist. It is commonly (incorrectly) assumed that a physician successful in clinical practice can easily transfer to managing/leading an organization. To be effective, the MD/MBA must bridge the cultures of the business world and medicine. Often just a single management course is sufficient to give the physician the knowledge they seek. MBA programs come in many forms and require choosing from a range of time commitments. Leaving a good clinical job in favor of the less-defined course of an MD/MBA can be daunting. Although a wide spectrum of opportunities are available, the MD/MBA may have to start over professionally, most likely with a pay cut, and will have to 'work their way up' again. A stigma exists for MD/MBAs because they are often perceived as caring more about business than about patients. Many MD/MBAs eventually choose to stay in full-time medical practice because financial and geographic stability may be more easily attained. The MBA is a good idea for the physicians who enjoy the intellectual challenges of business administration and proactively plan their own career.

  1. A Value-Added Approach to Selecting the Best Master of Business Administration (MBA) Program

    Science.gov (United States)

    Fisher, Dorothy M.; Kiang, Melody; Fisher, Steven A.

    2007-01-01

    Although numerous studies rank master of business administration (MBA) programs, prospective students' selection of the best MBA program is a formidable task. In this study, the authors used a linear-programming-based model called data envelopment analysis (DEA) to evaluate MBA programs. The DEA model connects costs to benefits to evaluate the…

  2. MAC Version 3.2, MBA Version 1.3 acceptance test summary report

    International Nuclear Information System (INIS)

    Russell, V.K.

    1994-01-01

    The K Basins Materials Accounting (MAC) and Materials Balance (MBA) programs had the Paradox Conversion to 4.0 ATP run to check out the systems. This report describes the results of the test and provides the signoff sheets associated with the testing. The test primarily concentrated on verifying that MAC and MBA software would run properly in the Paradox 4.0 environment. Changes in the MAC and MBA programs were basically limited to superficial items needed to accommodate the enhanced method of execution

  3. Edward U Lorenz

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education. Edward U Lorenz. Articles written in Resonance – Journal of Science Education. Volume 20 Issue 3 March 2015 pp 260-263 Classics. Predictability: Does the Flap of a Butterfly's Wings in Brazil Set off a Tornado in Texas? Edward U Lorenz · More Details Fulltext ...

  4. Attitudial Belief on Adoption of E-MBA Program in Malaysia

    Directory of Open Access Journals (Sweden)

    Razmah MAHMOD

    2005-04-01

    Full Text Available E-learning describes the use of information communications technology for learning beyond the boundaries of the conventional classroom. The objective of this paper is to determine what are the factors that are significant in explaining intention towards e-learning, particularly e-MBA adoption in Malaysia . Results indicated that trialability and image were significant influencing behavior intention towards e-MBA adoption.

  5. Admission Criteria for MBA Programs

    Directory of Open Access Journals (Sweden)

    Silvana Dakduk

    2016-11-01

    Full Text Available This paper reports a review of studies on admission criteria for MBA programs. The method consisted in a literary review based on a systematic search in international databases (Emerald, ABI/INFORM Global, ProQuest Education Journals, ProQuest European Business, ProQuest Science Journal, ProQuest Research Library, ProQuest Psychology Journals, ProQuest Social Science Journals and Business Source Complete of studies published from January 1990 to December 2013, which explore the academic performance of students or graduates of MBA programs. A quantitative review was performed. Results show that most researchers studied relations between GMAT (Graduate Management Admission Test and UGPA (Undergraduate Grade Point Average as predictors of GGPA (Graduate Grade Point Average. On the other hand, work experience and personal traits (such as personality, motivation, learning strategies, self-efficacy beliefs and achievement expectations and their relation with GGPA had been less studied, and results are not consistent enough to consider them valid predictors of student performance at this time.

  6. Delivering MBA Programs in Emerging Markets: The Challenge of National Culture

    Science.gov (United States)

    Jones, Stephanie

    2013-01-01

    Increasingly, Western-style MBA programs are being delivered in emerging markets, as the developed countries become more and more saturated with MBAs and related offerings. This article, based on the global experience of the author in teaching and assessing MBA modules including thesis and dissertation research and writing, suggests approaches to…

  7. BPM STABILTIY STUDIES FOR THE APS MBA UPGRADE

    Energy Technology Data Exchange (ETDEWEB)

    Lill, R.; Sereno, N.; Yang, B.

    2017-03-25

    The Advanced Photon Source (APS) is currently in the preliminary design phase for the multi-bend achromat (MBA) lattice upgrade. Beam stability is critical for the MBA and will require long term drift defined as beam mo-tion over a seven-day timescale to be no more than 1 mi-cron at the insertion device locations and beam angle change no more than 0.25 micro-radian. Mechanical stabil-ity of beam position monitor (BPM) pickup electrodes mounted on insertion device vacuum chambers place a fun-damental limitation on long-term beam stability for inser-tion device beamlines. We present the design and imple-mentation of prototype mechanical motion system (MMS) instrumentation for quantifying this type of motion specif-ically in the APS accelerator tunnel and experiment hall floor under normal operating conditions. The MMS pres-ently provides critical position information on the vacuum chamber and BPM support systems. Initial results of the R&D prototype systems have demonstrated that the cham-ber movements far exceed the long-term drift tolerance specified for the APS Upgrade MBA storage ring.

  8. Fødevareindustrien får sin egen MBA

    DEFF Research Database (Denmark)

    Stacey, Julia

    2004-01-01

    To internationale universiteter? Handelshøjskolen i Århus og Wageningen Business School udbyder til årsskiftet en unik international MBA, konkret målrettet fødevareindustrien. 'International MBA for the Food Business' skal sætte gang i kompetenceudviklingen i internationale fødevarevirksomheder og...... engelsk. Deltagerne i uddannelsen forventes at være fast tilknyttet en virksomhed under uddannelsesforløbet, idet en væsentlig del af uddannelsen er løsning af konkrete opgaver i egen virksomhed. Deltagerne skal i alt løse fire opgaver i egen virksomhed. Der igangsættes herved en udviklingsproces i...

  9. An Examination of Program Selection Criteria for Part-Time MBA Students

    Science.gov (United States)

    Colburn, Michael; Fox, Daniel E.; Westerfelt, Debra Kay

    2011-01-01

    Prospective graduate students select a graduate program as a result of a multifaceted decision-making process. This study examines the selection criteria that part-time MBA students used in selecting a program at a private university. Further, it analyzes the methods by which the students first learned of the MBA program. The authors posed the…

  10. Does the MBA Experience Support Diversity? Demographic Effects on Program Satisfaction

    Science.gov (United States)

    Arbaugh, J. B.; Bento, Regina; Hwang, Alvin

    2010-01-01

    Using data provided by graduates from 128 MBA programs, we examined the extent to which age, gender, and ethnicity predicted student perceptions of the MBA experience. We found that women and minorities were more likely to see program costs and the availability of financial support as significant factors in their program enrollment decisions than…

  11. Leadership Training in an MBA Program Using Peer-Led Team Learning

    Science.gov (United States)

    Dobson, Gregory; Frye, Robin; Mantena, Ravi

    2013-01-01

    Leadership training is an important part of any MBA program, but is often difficult to provide in an effective way. Over the last three years, we implemented a program of Peer-Led Team Learning in two core courses of our MBA curriculum, which we believe provides a good solution. The program combines leadership training with practical hands-on…

  12. Transports of acetate and haloacetate in Burkholderia species MBA4 are operated by distinct systems

    Directory of Open Access Journals (Sweden)

    Su Xianbin

    2012-11-01

    Full Text Available Abstract Background Acetate is a commonly used substrate for biosynthesis while monochloroacetate is a structurally similar compound but toxic and inhibits cell metabolism by blocking the citric acid cycle. In Burkholderia species MBA4 haloacetate was utilized as a carbon and energy source for growth. The degradation of haloacid was mediated by the production of an inducible dehalogenase. Recent studies have identified the presence of a concomitantly induced haloacetate-uptake activity in MBA4. This uptake activity has also been found to transport acetate. Since acetate transporters are commonly found in bacteria it is likely that haloacetate was transported by such a system in MBA4. Results The haloacetate-uptake activity of MBA4 was found to be induced by monochloroacetate (MCA and monobromoacetate (MBA. While the acetate-uptake activity was also induced by MCA and MBA, other alkanoates: acetate, propionate and 2-monochloropropionate (2MCPA were also inducers. Competing solute analysis showed that acetate and propionate interrupted the acetate- and MCA- induced acetate-uptake activities. While MCA, MBA, 2MCPA, and butyrate have no effect on acetate uptake they could significantly quenched the MCA-induced MCA-uptake activity. Transmembrane electrochemical potential was shown to be a driving force for both acetate- and MCA- transport systems. Conclusions Here we showed that acetate- and MCA- uptake in Burkholderia species MBA4 are two transport systems that have different induction patterns and substrate specificities. It is envisaged that the shapes and the three dimensional structures of the solutes determine their recognition or exclusion by the two transport systems.

  13. MD-11 PCA - Research flight team egress

    Science.gov (United States)

    1995-01-01

    This McDonnell Douglas MD-11 has parked on the flightline at NASA's Dryden Flight Research Center, Edwards, California, following its completion of the first and second landings ever performed by a transport aircraft under engine power only (on Aug. 29, 1995). The milestone flight, with NASA research pilot and former astronaut Gordon Fullerton at the controls, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when its normal control surfaces are disabled. Coming down the steps from the aircraft are Gordon Fullerton (in front), followed by Bill Burcham, Propulsion Controlled Aircraft (PCA) project engineer at Dryden; NASA Dryden controls engineer John Burken; John Feather of McDonnell Douglas; and Drew Pappas, McDonnell Douglas' project manager for PCA.

  14. MBA: a literature mining system for extracting biomedical abbreviations.

    Science.gov (United States)

    Xu, Yun; Wang, ZhiHao; Lei, YiMing; Zhao, YuZhong; Xue, Yu

    2009-01-09

    The exploding growth of the biomedical literature presents many challenges for biological researchers. One such challenge is from the use of a great deal of abbreviations. Extracting abbreviations and their definitions accurately is very helpful to biologists and also facilitates biomedical text analysis. Existing approaches fall into four broad categories: rule based, machine learning based, text alignment based and statistically based. State of the art methods either focus exclusively on acronym-type abbreviations, or could not recognize rare abbreviations. We propose a systematic method to extract abbreviations effectively. At first a scoring method is used to classify the abbreviations into acronym-type and non-acronym-type abbreviations, and then their corresponding definitions are identified by two different methods: text alignment algorithm for the former, statistical method for the latter. A literature mining system MBA was constructed to extract both acronym-type and non-acronym-type abbreviations. An abbreviation-tagged literature corpus, called Medstract gold standard corpus, was used to evaluate the system. MBA achieved a recall of 88% at the precision of 91% on the Medstract gold-standard EVALUATION Corpus. We present a new literature mining system MBA for extracting biomedical abbreviations. Our evaluation demonstrates that the MBA system performs better than the others. It can identify the definition of not only acronym-type abbreviations including a little irregular acronym-type abbreviations (e.g., ), but also non-acronym-type abbreviations (e.g., ).

  15. ECM using Edwards curves

    DEFF Research Database (Denmark)

    Bernstein, Daniel J.; Birkner, Peter; Lange, Tanja

    2013-01-01

    -arithmetic level are as follows: (1) use Edwards curves instead of Montgomery curves; (2) use extended Edwards coordinates; (3) use signed-sliding-window addition-subtraction chains; (4) batch primes to increase the window size; (5) choose curves with small parameters and base points; (6) choose curves with large...

  16. Faculty Salary as a Predictor of Student Outgoing Salaries from MBA Programs

    Science.gov (United States)

    Hamlen, Karla R.; Hamlen, William A.

    2016-01-01

    The authors' purpose was to investigate the predictive value of faculty salaries on outgoing salaries of master of business administration (MBA) students when controlling for other student and program variables. Data were collected on 976 MBA programs using Barron's "Guide to Graduate Business Schools" over the years 1988-2005 and the…

  17. An Industry Analysis of the MBA Market and the Competitive Positioning of the GSBPP

    National Research Council Canada - National Science Library

    Hager, Garrett W; King, Thomas T

    2007-01-01

    The purpose of this Master of Eusiness Administration (MBA) project is to perform an industry analysis of the MBA market utilizing the principles of industry analysis noted in Michael Porter's "Five Forces Analysis" model...

  18. Reinventing the MBA as a Rite of Passage for a Boundaryless Era

    Science.gov (United States)

    Kelan, Elisabeth; Jones, Rachel Dunkley

    2009-01-01

    Purpose: This paper aims to explore whether the rite of passage is still a useful model with which to conceptualise the MBA in the era of the boundaryless career. Design/methodology/approach: The paper examines the formative experiences of full-time MBA students at an elite business school, using in-depth qualitative interviews. Through a…

  19. Efficacy of MBA: On the Role of Network Effects in Influencing the Selection of Elective Courses

    Science.gov (United States)

    Roy, Vivek; Parsad, Chandan

    2018-01-01

    Purpose: The purpose of this paper is to outline the importance of social network effects in influencing the elective (courses) selection among masters of business administration (MBA) students and its role in influencing the efficacy of MBA. As such, given the enormous time and investment required for students to pursue an MBA and the role of…

  20. An Efficiency Comparison of MBA Programs: Top 10 versus Non-Top 10

    Science.gov (United States)

    Hsu, Maxwell K.; James, Marcia L.; Chao, Gary H.

    2009-01-01

    The authors compared the cohort group of the top-10 MBA programs in the United States with their lower-ranking counterparts on their value-added efficiency. The findings reveal that the top-10 MBA programs in the United States are associated with statistically higher average "technical and scale efficiency" and "scale efficiency", but not with a…

  1. An Industry Analysis of the MBA Market and the Competitive Positioning of the GSBPP

    National Research Council Canada - National Science Library

    Hager, Garrett W; King, Thomas T

    2007-01-01

    .... The intent of this project is to create an awareness of how these competitive forces: shape the MBA market, define the relationships hetween stakeholders within the market, and affect the overall attractiveness of the MBA market...

  2. Career Progression of the Pharmacy/MBA Professional: Characterization and Perceptions of the Combined Degree.

    Science.gov (United States)

    Daly, Christopher J; Tierney, Sarah-Elizabeth L; O'Brien, Erin; Fiebelkorn, Karl D; Jacobs, David M

    2017-05-01

    Objectives. To characterize pharmacy/MBA professionals during their entry-level and current positions and to describe their attitudes and perceptions toward their combined degree. Methods. A cross-sectional survey of University at Buffalo (UB) alumni who obtained both pharmacy and MBA degrees was used. An electronic survey was developed through collaboration with the UB School of Management and administered in winter 2015. Results. A total of 68/115 (59% response rate) pharmacy/MBA professionals responded to the survey. Post-graduate training was completed by 24% of respondents, and most commonly it was a residency program. After adjusting for inflation to 2014 dollars, the median entry-level salary for pharmacy/MBA professionals was $140,123 (mean = $144,327) and this increased to $179,947 (mean = $205,623) for those in their current position. Practice settings for entry-level professionals included pharmaceutical industry (25%) and chain pharmacies (18%). Most respondents believed that a combined degree helped in career advancement (85%) and made them more competitive in the job market (90%). Conclusion. Pharmacy/MBA professionals are well-compensated, work in a wide-range of professional settings, and have a high-level of satisfaction with their combined degree.

  3. Web-Based vs. Face-to-Face MBA Classes: A Comparative Assessment Study

    Science.gov (United States)

    Brownstein, Barry; Brownstein, Deborah; Gerlowski, Daniel A.

    2008-01-01

    The challenges of online learning include ensuring that the learning outcomes are at least as robust as in the face-to-face sections of the same course. At the University of Baltimore, both online sections and face-to-face sections of core MBA courses are offered. Once admitted to the MBA, students are free to enroll in any combination of…

  4. Cultural Intelligence (CQ) in MBA Curricula

    Science.gov (United States)

    Ahn, Mark J.; Ettner, Larry

    2013-01-01

    Purpose: The purpose of this paper is to investigate the role of cultural intelligence in MBA curricula. Shaping global corporate culture that manifests itself in powerful-shared values, group behavior, and persists despite changes in-group membership is decisive to organizational performance. In turn, cultural intelligence (CQ), defined, as an…

  5. Fuelwood production in Prince Edward Island

    International Nuclear Information System (INIS)

    McCallum, B.

    1992-01-01

    The most recent Prince Edward Island Fuelwood Survey occurred in 1990-91. Consumption of fuelwood rose again to 49% of Prince Edward Island's 43,170 households. Total residential fuelwood consumption was estimated to be 242,000 m 3 . The fuelwood industry makes an important contribution to the economy of Prince Edward Island. In the 1990-91 heating season, fuelwood valued at USD 9 million displaced approximately 43 million litres of domestic heating oil valued at USD 16.4 million. In addition, it is estimated that 70 cents of every dollar spent on fuelwood remains in the province and contributes spin-off benefits, whereas 90 cents of every dollar spent on heating oil is lost to the economy of Prince Edward Island. The percentage of people cutting their own fuelwood decreased from 52 in 1984-85 to only 23.4 in 1990-91. The governments of Canada and Prince Edward Island have implemented a series of Forest Resource Development Agreements (FRDAs) starting in 1983. The current 1988-1993 FRDA provides USD 24 million for research and incentives for reforestation and management of Prince Edward Island woodlots. It is expected that 3,800 Prince Edward Island woodlot owners will be participating in a woodlot management program by 1993. Silviculture treatments of hardwood stands include thinning, stand conversion (removal of lowgrade softwoods such as balsam fir in mainly hardwood stands), and shelterwood (strip) cutting, particularly in marginal stands. (9 refs.)

  6. MBA - WHAT STUDENTS AND ALUMNI THINK ABOUT THE ACCOMPLISHED COURSE, THEIR LEARNING, AND THE IMPACT ON THEIR CAREERS

    Directory of Open Access Journals (Sweden)

    Patrícia Teixeira Maggi da Silva

    2016-11-01

    Full Text Available The MBA is one of the most popular programs in management education today. Research conducted by accreditors organizations and specialized and internationally recognized journals regularly publish rankings of courses and schools to evaluate objective aspects related to MBA, including: salary increases, promotions, career and employability. The MBA also has been criticized, especially the lack of aligning of its curriculum to the needs of the business world and the real contribution to the development of managers able to deal with the challenges and the complexity of the contemporary business environment. In an effort to increase the understanding of the MBA, this article aims to describe, analyze and synthesize what students think about the MBA, highlighting how they evaluate the course, their learning and the impact on their careers. Empirically, we carried out a qualitative study with semi-structured interviews with 13 students of MBA with specialization of an institution of higher education in the city of São Paulo. The results indicate positive reviews about the course and the learning and the MBA alone does not guarantee rise of career and employability.

  7. MBA Internships: More Important than Ever

    Science.gov (United States)

    Dillon, Michael; McCaskey, Pat; Blazer, Eric

    2011-01-01

    Twenty years ago, in response to an existing vacuum in the literature, a national study of MBA internships at programs accredited by the Association to Advance Collegiate Schools of Business International (AACSB) was published (P. H. McCaskey, 1988). The descriptive article was written to aid educators and administrators in their decision making…

  8. Competitive Advantage of MBA for Physician Executives: A Systematic Literature Review.

    Science.gov (United States)

    Turner, Anthony D; Stawicki, Stanislaw P; Guo, Weidun Alan

    2018-06-01

    In response to systemic challenges facing the US healthcare system, many medical students, residents and practicing physicians are pursuing a Master in Business Administration (MBA) degree. The value of such proposition remains poorly defined. The aim of this review is to analyze current literature pertaining to the added value of MBA training for physician executives (PEs). We hypothesized that physicians who supplement their clinical expertise with business education gain a significant competitive advantage. A detailed literature search of four electronic databases (PubMed, SCOPUS, Embase and ERIC) was performed. Included were studies published between Jan 2000 and June 2017, focusing specifically on PEs. Among 1580 non-duplicative titles, we identified 23 relevant articles. Attributes which were found to add value to one's competitiveness as PE were recorded. A quality index score was assigned to each article in order to minimize bias. Results were tabulated by attributes and by publication. We found that competitive domains deemed to be most important for PEs in the context of MBA training were leadership (n = 17), career advancement opportunities (n = 12), understanding of financial aspects of medicine (n = 9) and team-building skills (n = 10). Among other prominent factors associated with the desire to engage in an MBA were higher compensation, awareness of public health issues/strategy, increased negotiation skills and enhanced work-life balance. Of interest, the learning of strategies for reducing malpractice litigation was less important than the other drivers. This comprehensive systemic review supports our hypothesis that a business degree confers a competitive advantage for PEs. Physician executives equipped with an MBA degree appear to be better equipped to face the challenge of the dynamically evolving healthcare landscape. This information may be beneficial to medical schools designing or implementing combined dual-degree curricula.

  9. The International Research Experience: Executive MBA Distinctiveness.

    Science.gov (United States)

    Ambrose, David M.; Pol, Louis G.

    1995-01-01

    The University of Nebraska's Executive Master's in Business Administration (MBA) program has integrated international research activities into the curriculum. The university contracted with domestic corporations to conduct studies on prospects for international business. Research assignments include assessment of competitors, economic evaluations,…

  10. FIRST BEAM TESTS OF THE APS MBA UPGRADE ORBIT FEEDBACK CONTROLLER

    Energy Technology Data Exchange (ETDEWEB)

    Sereno, N. S.; Arnold, N.; Brill, A.; Bui, H.; Carwardine, J.; Decker, G.; Deriy, B.; Emery, L.; Farnsworth, R.; Fors, T.; Keane, R.; Lenkszus, F.; Lill, R.; Paskvan, D.; Pietryla, A.; Shang, H.; Shoaf, S.; Veseli, S.; Wang, J.; Xu, S.; Yang, B.X.

    2017-03-25

    The new orbit feedback system required for the APS multi-bend acromat (MBA) ring must meet challenging beam stability requirements. The AC stability requirement is to correct rms beam motion to 10 % the rms beam size at the insertion device source points from 0.01 to 1000 Hz. The vertical plane represents the biggest challenge for AC stability which is required to be 400 nm rms for a 4 micron vertical beam size. In addition long term drift over a period of 7 days is required to be 1 micron or less at insertion de- vice BPMs and 2 microns for arc bpms. We present test re- sults of theMBA prototype orbit feedback controller (FBC) in the APS storage ring. In this test, four insertion device BPMs were configured to send data to the FBC for process- ing into four fast corrector setpoints. The configuration of four bpms and four fast correctors creates a 4-bump and the configuration of fast correctors is similar to what will be implemented in the MBA ring. We report on performance benefits of increasing the sampling rate by a factor of 15 to 22.6 kHz over the existing APS orbit feedback system, lim- itations due to existing storage ring hardware and extrapo- lation to theMBA orbit feedback design. FBC architecture, signal flow and processing design will also be discussed.

  11. Branding MBA Programs: The Use of Target Market Desired Outcomes for Effective Brand Positioning

    Science.gov (United States)

    Heslop, Louise A.; Nadeau, John

    2010-01-01

    Branding is about delivering on desired outcomes. The importance of positioning program offerings on the basis of outcomes sought in the education market is illustrated in this study of choice of an MBA program by prospective students. MBA fair attendees were surveyed and multiple methods were employed to determine the importance of desired…

  12. Group Work in the MBA Classroom: Improving Pedagogical Practice and Maximizing Positive Outcomes with Part-Time MBA Students

    Science.gov (United States)

    Rafferty, Patricia D.

    2013-01-01

    This article forms part of an exploration into how graduate students experience group work. A single case, embedded study was completed in 2011, which reveals insight and understanding into the manner in which part-time MBA students experience group work assignments and how these experiences contribute to their perception of positive group work…

  13. REVISITING SCHEIN (1965 STUDY ON THE MANAGERIAL VALUES AND ATTITUDES OF MBA STUDENTS

    Directory of Open Access Journals (Sweden)

    A. Gonul Demirel

    2015-04-01

    Full Text Available As schools are organized networks of socializing experiences which prepare individuals to act in society, MBA programs are the socializing media to prepare the future managers. Our study is “a partial replication” of the study done by Schein (1965. The same constructs are used in the questionnaire of the present study. Assuming that what is valued by managers influences how those individuals make business decisions, we aim to find out the managerial values and attitudes of MBA students. We also aim to draw the attention of the faculty members to think about what attitudes, beliefs, and values MBA students are learning and what might the faculty contributions be to the transfer of managerial values. Therefore, the main question of our study is “What are the major managerial values and attitudes of our MBA students?” A second intended contribution of this study is the validation of the scales. The goal of science is empirical generalization, or knowledge development. Systematically conducted replications with extensions facilitate this goal. Keeping this in mind our reconsidering the original constructs of the Schein (1965 study contributes to the validation of at least some of these original constructs.

  14. A Study on the Application of STP Marketing Strategy in the MBA Education Program of Universities in China

    Science.gov (United States)

    Zhang, Hongyi

    2008-01-01

    The MBA education has begun in America and now it has become mature after nearly one hundred years' development. Although China's MBA merely has a history of 17 years, it has already gained great achievements. In 1991, 9 universities in China had MBA program and 86 students enrolled in. In 2007, the two numbers were 127 and 59,776 respectively.…

  15. GPS-MBA: computational analysis of MHC class II epitopes in type 1 diabetes.

    Science.gov (United States)

    Cai, Ruikun; Liu, Zexian; Ren, Jian; Ma, Chuang; Gao, Tianshun; Zhou, Yanhong; Yang, Qing; Xue, Yu

    2012-01-01

    As a severe chronic metabolic disease and autoimmune disorder, type 1 diabetes (T1D) affects millions of people world-wide. Recent advances in antigen-based immunotherapy have provided a great opportunity for further treating T1D with a high degree of selectivity. It is reported that MHC class II I-A(g7) in the non-obese diabetic (NOD) mouse and human HLA-DQ8 are strongly linked to susceptibility to T1D. Thus, the identification of new I-A(g7) and HLA-DQ8 epitopes would be of great help to further experimental and biomedical manipulation efforts. In this study, a novel GPS-MBA (MHC Binding Analyzer) software package was developed for the prediction of I-A(g7) and HLA-DQ8 epitopes. Using experimentally identified epitopes as the training data sets, a previously developed GPS (Group-based Prediction System) algorithm was adopted and improved. By extensive evaluation and comparison, the GPS-MBA performance was found to be much better than other tools of this type. With this powerful tool, we predicted a number of potentially new I-A(g7) and HLA-DQ8 epitopes. Furthermore, we designed a T1D epitope database (TEDB) for all of the experimentally identified and predicted T1D-associated epitopes. Taken together, this computational prediction result and analysis provides a starting point for further experimental considerations, and GPS-MBA is demonstrated to be a useful tool for generating starting information for experimentalists. The GPS-MBA is freely accessible for academic researchers at: http://mba.biocuckoo.org.

  16. MAC Version 3.3, MBA Version 1.3 acceptance test summary report

    International Nuclear Information System (INIS)

    Russell, V.K.

    1994-01-01

    The K Basins Materials Accounting (MAC) and Materials Balance (MBA) programs had the Paradox Code Cleanup ATP run to check out the systems. This report describes the results of the test and provides the signoff sheets associated with the testing. The Acceptance Test results indicate that the MAC and MBA systems are ready for operation using the cleaned up code. The final codes were removed to the production space on the customer server on April 15th

  17. Factors Affecting Career Progress of MBA Students

    Directory of Open Access Journals (Sweden)

    Vivien T. Supangco

    2001-06-01

    Full Text Available This paper explored the factors that affect career progress of students in the MBA program of the University of the Philippines.To understand career progression, four measures of career progress were used in this study, namely: number of promotions, number of years in between promotions, total cash compensation, and number of administrative levels from the company president. On the other hand, the factors used to explain career progess included human capital, organizational, interpersonal and demographic variables.The results showed that the different measures of career progress had distinct determinants implying different dynamics. It appeared that measures of career progress that are sensitive to the value employers attach to the individual (Whitely, Dougherty, & Dreher, 1991 such as total compensation, total number of promotion and years per promotion were related with human capital factors such as work experience and number of companies worked for. On the other hand, measures that relate to centrality if the position, in which market forces have less impact, were associated with organizational variables such as organization size and the demographic variable gender.While gender did not explain variation in total compensation, number of promotions and number of uears between promotions, these null results are important for two reasons. First, it implies that the female MBA students were at par with their male counterparts as fas as these measures of career progress are concerned. Second, it challenges the generalizability of the finding of gender segregation at the organizational level-where men receive significantly higher wages that women-which is a common finding among studies done in the United States. The results using the MBA students as sample show that income and promotion parity may indeed be achievable and this brings hope to women in general.However, the statistical significance of gender in explaining career progress as centrality

  18. MBA1 encodes a mitochondrial membrane-associated protein required for biogenesis of the respiratory chain.

    Science.gov (United States)

    Rep, M; Grivell, L A

    1996-06-17

    The yeast MBA 1 gene (Multi-copy Bypass of AFG3) is one of three genes whose overexpression suppresses afg3-null and rca1-null mutations. Bypass of AFG3 and RCA1, whose products are essential for assembly of mitochondrial inner membrane enzyme complexes, suggests a related role for MBA1. The predicted translation product is a 30 kDa hydrophilic protein with a putative mitochondrial targeting sequence and no homology to any sequence in protein or EST databases. Gene disruption leads to a partial respiratory growth defect, which is more pronounced at temperatures above 30 degrees C. Concomitantly, amounts of cytochromes b and aa3 are reduced. A C-terminal c-myc-tagged MBA1 gene product is functional and is found associated with the mitochondrial inner membrane, from which it can he extracted by carbonate, but not by high salt. These observations give further support to a role of MBA1 in assembly of the respiratory chain.

  19. Ureaplasma Species Multiple Banded Antigen (MBA) Variation Is Associated with the Severity of Inflammation In vivo and In vitro in Human Placentae.

    Science.gov (United States)

    Sweeney, Emma L; Kallapur, Suhas G; Meawad, Simone; Gisslen, Tate; Stephenson, Sally-Anne; Jobe, Alan H; Knox, Christine L

    2017-01-01

    Background: The multiple banded antigen (MBA), a surface-exposed lipoprotein, is a proposed virulence factor of Ureaplasma spp. We previously demonstrated that the number of Ureaplasma parvum MBA size variants in amniotic fluid was inversely proportional to the severity of chorioamnionitis in experimentally infected pregnant sheep. However, the effect of ureaplasma MBA size variation on inflammation in human pregnancies has not been reported. Methods: Ureaplasmas isolated from the chorioamnion of pregnant women from a previous study ( n = 42) were speciated/serotyped and MBA size variation was demonstrated by PCR and western blot. Results were correlated with the severity of chorioamnionitis and cord blood cytokines. In vitro , THP-1-derived macrophages were exposed to recombinant-MBA proteins of differing sizes and NF-κB activation and cytokine responses were determined. Results: MBA size variation was identified in 21/32 (65.6%) clinical isolates (in 10 clinical isolates MBA size variation was unable to be determined). Any size variation (increase/decrease) of the MBA (regardless of Ureaplasma species or serovar) was associated with mild or absent chorioamnionitis ( P = 0.023) and lower concentrations of cord blood cytokines IL-8 ( P = 0.04) and G-CSF ( P = 0.008). In vitro , recombinant-MBA variants elicited different cytokine responses and altered expression of NF-κB p65. Conclusion: This study demonstrates that size variation of the ureaplasma MBA protein modulates the host immune response in vivo and in vitro .

  20. Ureaplasma antigenic variation beyond MBA phase variation: DNA inversions generating chimeric structures and switching in expression of the MBA N-terminal paralogue UU172.

    Science.gov (United States)

    Zimmerman, Carl-Ulrich R; Rosengarten, Renate; Spergser, Joachim

    2011-02-01

    Phase variation of the major ureaplasma surface membrane protein, the multiple-banded antigen (MBA), with its counterpart, the UU376 protein, was recently discussed as a result of DNA inversion occurring at specific inverted repeats. Two similar inverted repeats to the ones within the mba locus were found in the genome of Ureaplasma parvum serovar 3; one within the MBA N-terminal paralogue UU172 and another in the adjacent intergenic spacer region. In this report, we demonstrate on both genomic and protein level that DNA inversion at these inverted repeats leads to alternating expression between UU172 and the neighbouring conserved hypothetical ORF UU171. Sequence analysis of this phase-variable 'UU172 element' from both U. parvum and U. urealyticum strains revealed that it is highly conserved among both species and that it also includes the orthologue of UU144. A third inverted repeat region in UU144 is proposed to serve as an additional potential inversion site from which chimeric genes can evolve. Our results indicate that site-specific recombination events in the genome of U. parvum serovar 3 are dynamic and frequent, leading to a broad spectrum of antigenic variation by which the organism may evade host immune responses. © 2010 Blackwell Publishing Ltd.

  1. Ureaplasma antigenic variation beyond MBA phase variation: DNA inversions generating chimeric structures and switching in expression of the MBA N-terminal paralogue UU172

    Science.gov (United States)

    Zimmerman, Carl-Ulrich R; Rosengarten, Renate; Spergser, Joachim

    2011-01-01

    Phase variation of the major ureaplasma surface membrane protein, the multiple-banded antigen (MBA), with its counterpart, the UU376 protein, was recently discussed as a result of DNA inversion occurring at specific inverted repeats. Two similar inverted repeats to the ones within the mba locus were found in the genome of Ureaplasma parvum serovar 3; one within the MBA N-terminal paralogue UU172 and another in the adjacent intergenic spacer region. In this report, we demonstrate on both genomic and protein level that DNA inversion at these inverted repeats leads to alternating expression between UU172 and the neighbouring conserved hypothetical ORF UU171. Sequence analysis of this phase-variable ‘UU172 element’ from both U. parvum and U. urealyticum strains revealed that it is highly conserved among both species and that it also includes the orthologue of UU144. A third inverted repeat region in UU144 is proposed to serve as an additional potential inversion site from which chimeric genes can evolve. Our results indicate that site-specific recombination events in the genome of U. parvum serovar 3 are dynamic and frequent, leading to a broad spectrum of antigenic variation by which the organism may evade host immune responses. PMID:21255110

  2. Tissue inhibitor of matrix metalloproteinase-1 suppresses apoptosis of mouse bone marrow stromal cell line MBA-1.

    Science.gov (United States)

    Guo, L-J; Luo, X-H; Xie, H; Zhou, H-D; Yuan, L-Q; Wang, M; Liao, E-Y

    2006-05-01

    We investigated the action of tissue inhibitor of metalloproteinase-1 (TIMP-1) on apoptosis and differentiation of mouse bone marrow stromal cell line MBA-1. TIMP-1 did not affect alkaline phosphatase (ALP) activity, suggesting that it is not involved in osteoblastic differentiation in MBA-1 cells. However, TIMP-1 inhibited MBA-1 apoptosis induced by serum deprivation in a dose-dependent manner. Our study also showed increased Bcl-2 protein expression and decreased Bax protein expression with TIMP-1 treatment. TIMP-1 decreased cytochrome c release and caspase-3 activation in MBA-1 cells. TIMP-1 activated phosphatidylinositol 3-kinase (PI3-kinase) and c-Jun N-terminal kinase (JNK), and the PI3-kinase inhibitor LY294002 or the JNK inhibitor SP600125 abolished its antiapoptotic activity. To investigate whether antiapoptotic action of TIMP-1 was mediated through its inhibition on MMP activities, we constructed mutant TIMP-1 by side-directed mutagenesis, which abolished the inhibitory activity of MMPs by deletion of Cys1 to Ala4. Wild-type TIMP-1 and mutant TIMP-1 expression plasmids were transfected in MBA-1 cells, and results showed that mutant TIMP-1 still protected the induced MBA-1 cell against apoptosis. These data suggest that TIMP-1 antiapoptotic actions are mediated via the PI3-kinase and JNK signaling pathways and independent of TIMP-1 inhibition of MMP activities.

  3. Edward Said

    DEFF Research Database (Denmark)

    Botofte, John; Jensen, Lars

    En gennemgang af Edward Saids forfatterskab. Skønt gennemgangen er relativt kronologisk, er det en hovedpointe med bogen at vise samspillet mellem Saids mangefacetterede interesser og publikationer. Endelig indeholder bogen et bibliografiessay og et essay om arven efter Said inden for det postkol...

  4. EDWARD SUESS AND RUSSIAN GEOLOGISTS

    Directory of Open Access Journals (Sweden)

    Boris A. Natal’in

    2011-01-01

    Full Text Available The publication is devoted to the history of one of the greatest concepts of tectonics of Asia, that has been widely accepted and yet obliterated with time, while the splendors of this concept are doubtful. Numerous citations in the Russian papers to «The Face of the Earth» by Edward Suess and the fact that he was elected a Corresponding Member of the Imperial Saint Petersburg Academy of Sciences clearly demonstrate how highly Suess’s contribution to studies of the structure and geological evolution of Asia was valued by the Russian geological community. Suess’s letters to Vladimir A. Obruchev give evidence how close and productive the relationship between Edward Suess and the Russian researchers was in the late 19th and the early 20th centuries and also illustrate how the great tectonic concept of Asia [Suess, 1908] was born and developed. The idea of centrifugal propagation of tectonic waves of the Altaids from a continental node located somewhere in Siberia was mainly inspired by Suess’s profound scientific intuition. The idea matured after Edward Suess got acquainted with Ivan D. Chersky’s paper [Черский, 1886] that greatly facilitated in shaping and improving this idea. It was mailed to Suess by Vladimir A. Obruchev who translated the paper, attached his own map and provided explanations to Chersky’s ideas. The available historical documents suggest that Vladimir A. Obruchev facilitated communication between the Russian geologists, on the one side, and Edward Suess and other Austrian geologists who conducted geological studies in Asia, on the other side. Being actively involved in exchange of publications and cooperation in field data processing, Edward Suess was aware of all the details of the Russian geological studies.In addition to the concept of tectonic arcs of the Altaids and descriptions of main geological structures located in Northern Asia and China, Edward Suess adopted a concept of disjunctive dislocations

  5. Competitive Intelligence for MBA Students: Credit Courses

    OpenAIRE

    Kirkwood, Hal P, Jr

    2016-01-01

    Poster was presented at the Business & Finance Division Poster Session at the Special Libraries Association Annual Conference in Philadelphia, PA, 2016. Focus of the poster is on the credit-level courses taught by Prof Hal Kirkwood to MBA students in the Krannert Graduate School of Management on the topics of international business research and an introduction to competitive intelligence.

  6. The Effects of Part-Time MBA Programs on Students: The Relationships between Students and Their Employers

    Science.gov (United States)

    Prince, Melvin; Burns, David J.; Manolis, Chris

    2014-01-01

    The authors explore how the relationship between part-time master of business administration (MBA) students and their employers changes as students proceed through their MBA program by examining the degree to which students are integrated into their employer organizations. Significant positive relationships observed between students' progress…

  7. mba.com Prospective Students Survey. 2015 Survey Report

    Science.gov (United States)

    Schoenfeld, Gregg

    2015-01-01

    This 2015 "mba.com Prospective Students Survey Report" explores the motivations, career goals, preferred program types, financial choices, decision time lines, and intended study destinations of individuals interested in pursuing a graduate management education. Findings analyzed in the report represent responses from nearly 12,000…

  8. Improving the sensitivity of immunoassay based on MBA-embedded Au@SiO2 nanoparticles and surface enhanced Raman spectroscopy

    Science.gov (United States)

    Wei, Chao; Xu, Min-Min; Fang, Cong-Wei; Jin, Qi; Yuan, Ya-Xian; Yao, Jian-Lin

    2017-03-01

    Traditional "sandwich" structure immunoassay is mainly based on the self-assembly of "antibody on solid substrate-antigen-antibody with nanotags" architectures, and the sensitivity of this strategy is critically depended on the surface enhanced Raman scattering (SERS) activities and stability of nanotags. Therefore, the rational design and fabrication on the SERS nanotags attracts the common interests to the bio-related detecting and imaging. Herein, silica encapsulated Au with mercaptobenzoic acid (MBA) core-shell nanoparticles (Au-MBA@SiO2) are fabricated instead of the traditional naked Au or Ag nanoparticles for the SERS-based immunoassay on human and mouse IgG antigens. The MBA molecules facilitate the formation of continuous pinhole-free silica shell and are also used as SERS labels. The silica shell is employed to protect MBA labels and to isolate Au core from the ambient solution for blocking the aggregation. This shell also played the similar role to BSA in inhibiting the nonspecific bindings, which allowed the procedures for constructing "sandwich" structures to be simplified. All of these merits of the Au-MBA@SiO2 brought the high performance in the related immunoassay. Benefiting from the introduction of silica shell to encapsulate MBA labels, the detection sensitivity was improved by about 1- 2 orders of magnitude by comparing with the traditional approach based on naked Au-MBA nanoparticles. This kind of label-embedded core-shell nanoparticles could be developed as the versatile nanotags for the bioanalysis and bioimaging.

  9. Empirical angle-dependent Biot and MBA models for acoustic anisotropy in cancellous bone

    International Nuclear Information System (INIS)

    Lee, Kang ll; Hughes, E R; Humphrey, V F; Leighton, T G; Choi, Min Joo

    2007-01-01

    The Biot and the modified Biot-Attenborough (MBA) models have been found useful to understand ultrasonic wave propagation in cancellous bone. However, neither of the models, as previously applied to cancellous bone, allows for the angular dependence of acoustic properties with direction. The present study aims to account for the acoustic anisotropy in cancellous bone, by introducing empirical angle-dependent input parameters, as defined for a highly oriented structure, into the Biot and the MBA models. The anisotropy of the angle-dependent Biot model is attributed to the variation in the elastic moduli of the skeletal frame with respect to the trabecular alignment. The angle-dependent MBA model employs a simple empirical way of using the parametric fit for the fast and the slow wave speeds. The angle-dependent models were used to predict both the fast and slow wave velocities as a function of propagation angle with respect to the trabecular alignment of cancellous bone. The predictions were compared with those of the Schoenberg model for anisotropy in cancellous bone and in vitro experimental measurements from the literature. The angle-dependent models successfully predicted the angular dependence of phase velocity of the fast wave with direction. The root-mean-square errors of the measured versus predicted fast wave velocities were 79.2 m s -1 (angle-dependent Biot model) and 36.1 m s -1 (angle-dependent MBA model). They also predicted the fact that the slow wave is nearly independent of propagation angle for angles about 50 0 , but consistently underestimated the slow wave velocity with the root-mean-square errors of 187.2 m s -1 (angle-dependent Biot model) and 240.8 m s -1 (angle-dependent MBA model). The study indicates that the angle-dependent models reasonably replicate the acoustic anisotropy in cancellous bone

  10. MBA Attitudes toward Business: What We Don't Know Can Hurt Us or Help Us

    Science.gov (United States)

    Lundstrom, William J.

    2011-01-01

    MBA students are often treated as a blank sheet of paper on which the MBA program and its faculty etch and imprint the knowledge and philosophy of business success. Implicit in this thinking is that students are willing neophytes in this ritualistic process without a perceptual screen shaping and molding the content being espoused by legions of…

  11. Evaluating Market Orientation of an Executive MBA Program.

    Science.gov (United States)

    Dubas, Khalid M.; Ghani, Waqar I.; Davis, Stanley; Strong, James T.

    1998-01-01

    A study assessed the market orientation of the executive Master's in Business Administration (MBA) program at Saint Joseph's University (Pennsylvania) in terms of 12 skills and knowledge areas that reflect effective managerial performance and the student-executives' perceptions of program strengths and weaknesses in delivering these skills.…

  12. Fürchtet China Edward Snowden?

    OpenAIRE

    Rühlig, Tim

    2013-01-01

    Vielfach ist argumentiert worden, China sei einer der Hauptprofiteure von den Enthüllungen des ehemaligen amerikanischen Geheimdienstmitarbeiters Edward Snowden. Amerikas früherer Vizepräsident Dick Cheney sieht in ihm gar einen Spion der Volksrepublik China. Peking wies das sofort zurück. Ein Blick auf die chinesische Diskussion um Edward Snowden zeigt: Nicht nur Cheneys Vermutung schießt deutlich über das Ziel hinaus. Denn die chinesische Führung beobachtet die Entwicklung gleichsam aufmerk...

  13. Factors Affecting Perceived Learning, Satisfaction, and Quality in the Online MBA: A Structural Equation Modeling Approach

    Science.gov (United States)

    Sebastianelli, Rose; Swift, Caroline; Tamimi, Nabil

    2015-01-01

    The authors examined how six factors related to content and interaction affect students' perceptions of learning, satisfaction, and quality in online master of business administration (MBA) courses. They developed three scale items to measure each factor. Using survey data from MBA students at a private university, the authors estimated structural…

  14. Developing Content for an M.B.A. Communications Class.

    Science.gov (United States)

    Shelby, Annette N.

    1983-01-01

    Outlines an M.B.A. communications course which includes source materials and content development frameworks for four different topic areas: (1) company, industry, and organization data; (2) management theory and organizational design; (3) crisis communication; and (4) issues management. (RAE)

  15. The liquid scintillation counting efficiency for 137mCs+137mBa and ''129 I; 'Eficiencias de recuento por centelleo liquido para el Cs+13 mBa y ''129 I

    Energy Technology Data Exchange (ETDEWEB)

    Grau CarLes, A.; Grau Malonda, A.

    1995-07-01

    We compute the liquid scintillation counting efficiency for 137Cs+137mBa and ''129 I taking into account the scintillator chemical composition. We consider the beta transition shape factors for the for bidden beta transitions of these nuclides, and the effects of 137mBa and 129mXe half-lives on the total counting efficiency. (Author) 8 refs.

  16. Electronic and vibrational signatures of the Au102(p-MBA)44 cluster.

    Science.gov (United States)

    Hulkko, Eero; Lopez-Acevedo, Olga; Koivisto, Jaakko; Levi-Kalisman, Yael; Kornberg, Roger D; Pettersson, Mika; Häkkinen, Hannu

    2011-03-23

    Optical absorption of a gold nanocluster of 102 Au atoms protected by 44 para-mercaptobenzoic acid (p-MBA) ligands is measured in the range of 0.05-6.2 eV (mid-IR to UV) by a combination of several techniques for purified samples in solid and solution phases. The results are compared to calculations for a model cluster Au(102)(SMe)(44) based on the time-dependent density functional theory in the linear-response regime and using the known structure of Au(102)(p-MBA)(44). The measured and calculated molar absorption coefficients in the NIR-vis region are comparable, within a factor of 2, in the absolute scale. Several characteristic features are observed in the absorption in the range of 1.5-3.5 eV. The onset of the electronic transitions in the mid-IR region is experimentally observed at 0.45 ± 0.05 eV which compares well with the lowest calculated transition at 0.55 eV. Vibrations in the ligand layer give rise to fingerprint IR features below the onset of low-energy metal-to-metal electronic transitions. Partial exchange of the p-MBA ligand to glutathione does not affect the onset of the electronic transitions, which indicates that the metal core of the cluster is not affected by the ligand exchange. The full spectroscopic characterization of the Au(102)(p-MBA)(44) reported here for the first time gives benchmarks for further studies of manipulation and functionalization of this nanocluster to various applications.

  17. Historical sites at the Prince Edward islands

    CSIR Research Space (South Africa)

    Cooper, J

    1986-07-01

    Full Text Available This report gives the results of a workshop held on historical sites at the sub-Antarctic Prince Edward islands, southern Indian Ocean. All known visits and sojourns on the Prince Edward islands up to 1948 are tabulated. All known historical sites...

  18. American Society for Dermatologic Surgery

    Science.gov (United States)

    ... medical attendees. Your input is critical to future programming as we plan the 2018 ASDS Annual Meeting, ... 2017 recipients were Murad Alam, MD, MBA; Seemal R. Desai, MD; Jeffrey S. Dover, MD; George J. Hruza, ...

  19. Electronic structure of thiolate-covered gold nanoparticles: Au102(MBA)44.

    Science.gov (United States)

    Li, Yan; Galli, Giulia; Gygi, François

    2008-09-23

    We present first principles, density functional theory (DFT) calculations of the structural and electronic properties of thiolate-protected gold nanoparticles [Au(102)(MBA)(44) ] that have been recently crystallized and measured by X-ray diffraction. Our calculations yield structural properties in very good agreement with experiment and reveal the impact of thiolate adsorption on both the surface geometry and the electronic structure of the gold core; in particular, within DFT we observe the emergence of an energy gap of about 0.5 eV, upon MBA adsorption. Using a localized orbital analysis, we characterize the electron distribution in the nanoparticle and provide insight into the bonding of thiolates on curved gold surfaces.

  20. An Analysis of Multinational Corporations' Perception of Their Requirements for International M.B.A. Degree Holders.

    Science.gov (United States)

    Colquitt, J.; And Others

    This study was undertaken to assess: (1) the U.S. corporate demand for Americans holding an MBA degree with a concentration in International Management, (2) the U.S. corporate demand for foreign nationals holding a similar American MBA degree, and (3) the corporate perception of the value of foreign languages in such an international curriculum. A…

  1. An Industry Analysis of the MBA Market and the Competitive Positioning of the GSBPP

    Science.gov (United States)

    2007-03-01

    appropriations and make up the rest through philanthropy .” (MBA.com, 2005a) GMAC’s Selections recently studied the naming gifts that business schools 23...ranked programs. Although the Top 20 are considered the elite , making the Top 50 is still an accomplishment. Below the ranked schools are the non...control to ever gain access into the upper echelon 141 of the MBA elite , at least in terms of rankings. The accreditation serves more to validate its

  2. Kinetic investigation and lifetime prediction of Cs-NIPAM-MBA-based thermo-responsive hydrogels.

    Science.gov (United States)

    Othman, Muhammad Bisyrul Hafi; Khan, Abbas; Ahmad, Zulkifli; Zakaria, Muhammad Razlan; Ullah, Faheem; Akil, Hazizan Md

    2016-01-20

    This study attempted to clarify the influence of a cross-linker, N,N-methylenebisacrylamide (MBA), and N-isopropylacrylamide (NIPAM) on the non-isothermal kinetic degradation, solid state and lifetime of hydrogels using the Flynn-Wall-Ozawa (F-W-O), Kissinger, and Coats-Redfern (C-Red) methods. The series of dual-responsive Cs-PNIPAM-MBA microgels were synthesized by soapless-emulsion free radical copolymerization in an aqueous medium at 70 °C. The thermal properties were investigated using thermogravimetric analysis (TG) and differential scanning calorimetry (DSC) under nitrogen atmosphere. The apparent activation energy using the chosen Flynn-Wall-Ozawa and Kissinger methods showed that they fitted each other. Meanwhile, the type of solid state mechanism was determined using the Coats-Redfern method proposed for F1 (pure Cs) and F2 (Cs-PNIPAM-MBA hydrogel series) types, which comprise random nucleation with one nucleus reacting on individual particles, and random nucleation with two nuclei reacting on individual particles, respectively. On average, a higher Ea was attributed to the greater cross-linking density of the Cs hydrogel. Copyright © 2015 Elsevier Ltd. All rights reserved.

  3. TEACHING METHODS IN MBA AND LIFELONG LEARNING PROGRAMMES FOR MANAGERS

    Directory of Open Access Journals (Sweden)

    Jarošová, Eva

    2017-09-01

    Full Text Available Teaching methods in MBA and Lifelong Learning Programmes (LLP for managers should be topically relevant in terms of content as well as the teaching methods used. In terms of the content, the integral part of MBA and Lifelong Learning Programmes for managers should be the development of participants’ leadership competencies and their understanding of current leadership concepts. The teaching methods in educational programmes for managers as adult learners should correspond to the strategy of learner-centred teaching that focuses on the participants’ learning process and their active involvement in class. The focus on the participants’ learning process also raises questions about whether the programme’s participants perceive the teaching methods used as useful and relevant for their development as leaders. The paper presents the results of the analysis of the responses to these questions in a sample of 54 Czech participants in the MBA programme and of lifelong learning programmes at the University of Economics, Prague. The data was acquired based on written or electronically submitted questionnaires. The data was analysed in relation to the usefulness of the teaching methods for understanding the concepts of leadership, leadership skills development as well as respondents’ personal growth. The results show that the respondents most valued the methods that enabled them to get feedback, activated them throughout the programme and got them involved in discussions with others in class. Implications for managerial education practices are discussed.

  4. Alternate phase variation in expression of two major surface membrane proteins (MBA and UU376) of Ureaplasma parvum serovar 3.

    Science.gov (United States)

    Zimmerman, Carl-Ulrich R; Stiedl, Thomas; Rosengarten, Renate; Spergser, Joachim

    2009-03-01

    Ureaplasma urealyticum and Ureaplasma parvum are commensals and pathogens of the human urogenital tract and of newborn infants. There are four distinct U. parvum serovars and 10 distinct U. urealyticum serovars. Both species possess a distinct immunodominant variable surface protein, the multiple banded antigen (MBA), which shows size variability among isolates as a result of changes in the number of C-terminal repeating units. Adjacent to the MBA gene (UU375) lies UU376, which was annotated as 'Ureaplasma-specific conserved hypothetical gene'. In four different strains of U. parvum serovar 3, we demonstrated expression of UU376 by Western blot analysis and phase variation between UU376, here designated Upvmp376 (Ureaplasma phase-variable membrane protein 376), and MBA after application of selective pressure with hyperimmune antisera directed against either protein. By Southern blot analysis, we found that the switch between MBA and Upvmp376 expression is associated with a DNA inversion event in which the nonrepetitive region of the MBA gene and its putative promoter region are opposed to either the repetitive region of MBA or UU376. We propose that in U. parvum serovar 3, and presumably in all U. parvum and U. urealyticum, an inversion event at specific sites effects an alternate ON/OFF switching of the genes UU375 and UU376.

  5. Meeting the specifications for mechanical-biological waste treament and dumping; Umsetzung der Ablagerungsanforderungen im MBA- und Deponiebetrieb

    Energy Technology Data Exchange (ETDEWEB)

    Ketelsen, K. [IBA Ingenieurbuero fuer Abfallwirtschaft und Entsorgung GmbH, Hannover (Germany)

    2001-07-01

    The new German ordinances will have a dramatic influence on the waste treatment processes and air/exhaust management in mechanical-biological waste treatment plants. The potentials of process control and optimization should be fully utilized. The extensive in-service inspections and specifications will change the requirements on the process and staff qualification. The additional cost must be balanced by technically and economically feasible projecting and solutions. The need to keep up with thermal processes will lead to the construction of plants with a size of 50,000 Mg/a and more as these have higher economic efficiency, i.e. small regional utilities will have to co-operate. In mechanical-biological waste treatment plants, about 40-50% of the total cost is accounted for by the waste treatment process, i.e. economic efficiency will depend on the cost of dumping of the stabilized fine-grained fraction(about 20%) and the cost of utilization of the high-calorific waste (about 30%). In view of the high fixed cost, mechanical-biological waste treatment concepts will be economically efficient only if the plant capacity is fully utilized. [German] Mit Verabschiedung der Verordnungen ist die MBA 'gesellschaftsfaehiger' geworden. Die Verordnungen werden einen nachhaltigen Einfluss auf die Verfahrenstechnik und das gesamte Luft-/Abgasmanagement haben. Die Entwicklungspotentiale in der Prozesssteuerung und -optimierung muessen verstaerkt ausgeschoepft werden. Durch die geforderten umfangreichen Untersuchungs- und Nachweispflichten werden sich die Anforderungen an die Betriebsfuehrung und Personalqualifikation veraendern. Die aus den hoeheren Anforderungen resultierenden Mehrkosten muessen durch technisch und wirtschftlich sinnvolle Planungen und Loesungen in vertretbaren Grenzen gehalten werden. Die Notwendigkeit zur Wirtschaftlichkeit im Wettbewerb mit rein thermischen Verfahren wird auch bei den MBA zur Realisierung wirtschaftlicher Anlagengroessen von groesser

  6. Career Expectations and Perceptions of Part-Time MBA Students

    Science.gov (United States)

    Fish, Lynn A.; Fish, Lauren A.

    2010-01-01

    In the U.S., part-time MBA students regard work/life balance as the critical factor that drives career expectations and perceptions. Job aspects and benefits/compensation closely follow in importance, while employee relations are valued less. Within work/life balance, students value job location, travel time, and telecommuting. Promotional…

  7. Síndrome de Edwards asociado a inmunodeficiencia combinada Edwards' syndrome associated to combined immunodeficiency

    Directory of Open Access Journals (Sweden)

    Vianed Marsán Suárez

    2011-09-01

    Full Text Available El síndrome de Edwards es originado por un desbalance cromosómico representado por una trisomía 18. Alrededor de 95 % de los pacientes corresponden a trisomía completa, donde están presentes múltiples malformaciones en órganos y sistemas. El 5 % restante pertenece a trisomía parcial o mosaicismo, con un fenotipo incompleto por la ausencia de algunas anomalías típicas del síndrome. La inmunodeficiencia es una manifestación poco frecuente del síndrome Edwards. Se presenta el caso de una paciente de 9 meses de edad con trisomía 18 parcial e infecciones severas recurrentes desde la etapa neonatal, asociadas a anemia, linfopenia, trombocitopenia y neutrofilia. La ecografía mostró una hipoplasia del timo. Se encontraron cifras disminuidas de linfocitos TCD4+, CD8+ y de células asesinas naturales. La cuantificación de linfocitos B fue normal. Se hallaron concentraciones normales de inmunoglobulinas séricas IgM e IgG y disminuidas de IgA. Se encontró una disminución de la actividad hemolítica total de la vía clásica del complemento. No se encontraron alteraciones en la función opsonofagocítica. Se diagnosticó una inmunodeficiencia combinada asociada, hecho que demostró la heterogeneidad de la expresión clínica del síndrome Edwards y la relación entre el defecto cromosómico y la formación del sistema inmune en el período intrauterino.Edwards' syndrome is caused by a chromosomal imbalance represented by trisomy 18. Complete trisomy accounts for 95% of patients who present multiple malformations in organs and systems. The remaining 5% presents partial trisomy or mosaicism, with incomplete phenotype due to lack of some typical anomalies of this syndrome. Immunodeficiency is a rare manifestation of Edwards' syndrome. The case of a 9-months old female patient with partial trisomy 18 and recurrent severe infections since the neonatal phase, all associated to anemia, lymphopenia, thrombocytopenia and neutrophilia, was

  8. Edward Banka Gariba

    African Journals Online (AJOL)

    Edward Banka Gariba. World Bank 1989. Sub-Saharan Africa: From crisis to sustainable growth, A long term perspective study. Washington, D.C., The World Bank. Zartman, I. William 1997. Introduction. In: Zartman, I. William ed. Governance as conflict management: Politics and violence in West Africa. Washington, D.C. ...

  9. Ethics Training and Workplace Ethical Decisions of MBA Professionals

    Science.gov (United States)

    Romious, Tamar S.; Thompson, Randall; Thompson, Elizabeth

    2016-01-01

    We recruited 15 MBA professionals in the St. Louis, Missouri metropolitan area to explore experiences and perceptions of classroom ethics training and ethical experiences in the workplace. Telephone interviews were conducted using open-ended questions to collect data that were uploaded to NVivo 10 for qualitative analysis. As a result of the data…

  10. MD-11 PCA - View of aircraft on ramp

    Science.gov (United States)

    1995-01-01

    This McDonnell Douglas MD-11 is taxiing to a position on the flightline at NASA's Dryden Flight Research Center, Edwards, California, following its completion of the first and second landings ever performed by a transport aircraft under engine power only (on Aug. 29, 1995). The milestone flight, with NASA research pilot and former astronaut Gordon Fullerton at the controls, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when its normal control surfaces are disabled. The Propulsion-Controlled Aircraft (PCA) system uses standard autopilot controls already present in the cockpit, together with the new programming in the aircraft's flight control computers. The PCA concept is simple. For pitch control, the program increases thrust to climb and reduces thrust to descend. To turn right, the autopilot increases the left engine thrust while decreasing the right engine thrust. The initial Propulsion-Controlled Aircraft studies by NASA were carried out at Dryden with a modified twin-engine F-15 research aircraft.

  11. The Challenges of Globalisation: Delivering an MBA Programme in Eritrea.

    Science.gov (United States)

    Dence, Roger; O'Toole, John

    1999-01-01

    Describes the experiences of delivering an MBA (Master in Business Administration) program in Eritrea (North East Africa) through the United Kingdom's Open University. Discusses tutoring teams that travel to Eritrea, localizing case examples and assignments, sensitivity to local cultural contexts, writing assignments, student assessment, and…

  12. Preparation and characterization of nanosized P(NIPAM-MBA) hydrogel particles and adsorption of bovine serum albumin on their surface.

    Science.gov (United States)

    Zhu, Xiaoli; Gu, Xiangling; Zhang, Lina; Kong, Xiang-Zheng

    2012-09-24

    Thermosensitive polymer hydrogel particles with size varying from 480 to 620 nm were prepared through precipitation copolymerization of N-isopropylacrylamide with N,N'-methylenebisacrylamide (MBA) in water with ammonium persulfate as the initiator. Only polymer hydrogels without any coagula were obtained when MBA concentration in the monomer mixture was kept between 2.5 and 10.0 wt%; with increased MBA concentration, the monomer conversion was enhanced, the size of the hydrogels was increased, and their shrinking was lessened when heated from 25°C to 40°C. Bovine serum albumin adsorption on the surface of the hydrogels of different MBA content was measured at different pH levels and under different temperatures. The results demonstrated that the adsorption of the protein on the hydrogels could be controlled by adjusting the pH, the temperature of adsorption, and the crosslinking in the hydrogels. The results were interpreted, and the mechanisms of the polymerization were proposed.

  13. Studies on preparing and adsorption property of grafting terpolymer microbeads of PEI-GMA/AM/MBA for bilirubin.

    Science.gov (United States)

    Gao, Baojiao; Lei, Haibo; Jiang, Liding; Zhu, Yong

    2007-06-15

    Crosslinking copolymer microbeads with a diameter range of 100-150 microm were synthesized by suspension copolymerization of glycidyl methacrylate (GMA), acrylamide (AM) and N,N'-methylene bisacrylamide (MBA). Subsequently, polyethyleneimine (PEI) was grafted on the surfaces of the terpolymer microbeads GMA/AM/MBA via the ring-opening reaction of the epoxy groups, and the grafting microbeads PEI-GMA/AM/MBA were prepared. In this paper, the adsorption property of the grafting microbeads for bilirubin was mainly investigated, and the effects of various factors, such as pH value, ionic strength and grafting degree of PEI on the surface of grafting microbeads and the adsorption capacity of the grafting microbeads for bilirubin were examined. The batch adsorption experiment results show that by right of the action of grafted polyamine macromolecules PEI, the grafting microbeads PEI-GMA/AM/MBA have quite strong adsorption ability for bilirubin; the isotherm adsorption conforms to Freundlich equation. The pH value of the medium affects the adsorption capacity greatly, As in the nearly neutral solutions with pH 6, the grafting microbeads have the strongest adsorption ability for bilirubin, whereas in acidic and basic solutions their adsorption ability is weak. The ionic strength hardly affects the adsorption ability of the grafting microbeads. The grafting degree of PEI on the surfaces of the grafting microbeads also has a great effect on the adsorption capacity, and higher the grafting degree of PEI on the surface of the microbead PEI-GMA/AM/MBA, the stronger is the adsorption ability of the microbeads.

  14. Histologic and histomorphometric evaluation of two grafting materials Cenobone and ITB-MBA in open sinus lift surgery.

    Science.gov (United States)

    Amoian, Babak; Seyedmajidi, Maryam; Safipor, Hamidreza; Ebrahimipour, Sediqe

    2016-01-01

    Alveolar ridge reduction caused after tooth extraction can be minimized through ridge preservation and application of graft materials. The aim of this study was to compare the histologic and histomorphometric aspects of bone particulated allografts, Cenobone and ITB-MBA, in the reconstruction of vertical alveolar ridge after maxillary sinus augmentation. This clinical trial was performed among 20 patients. The participants were randomly divided into two groups of 10 participants. The first group received Cenobone and the second group received ITB-MBA. Tissue samples were prepared 6 months later at the time of implant installation and after successful maxillary sinus floor augmentation. Tissue sections were examined under a light microscope. The data were analyzed by Chi-square and t -test. The mean trabecular thickness of the samples in the Cenobone group was 13.61 ± 7.47 μm compared to 13.73 ± 7.37 μm in the ITB-MBA group ( P = 0.93). A mild inflammation process (Grade 1) was detected in both the groups. The amount of remaining biomaterial in the Cenobone group was estimated to be 8 ± 19% vs. 7 ± 12% in the ITB-MBA group ( P = 0.30). Bone formation was reported 49.71% in the Cenobone group vs. 40.76% in the ITB-MBA group ( P = 0.68). The mean newly formed vessel in the Cenobone group was 0.64 ± 0.7 vs. 1.5 ± 2.3 in the ITB-MBA group ( P = 0.14). There was no significant difference between the two groups of patients regarding trabecular thickness, remaining biomaterial allograft, and the density of blood vessels after sinus floor elevation; hence, there was no difference between the two groups regarding implant outcome. More designed studies as randomized controlled trials and controlled clinical trials, which evaluate the long-term implant outcome; comparing the different bone graft materials is also required to improve evidence on survival and success rate.

  15. Lessons Jesuit Business Programs Can Learn from Chinese MBA Programs

    Directory of Open Access Journals (Sweden)

    Mary Ann Pauline McGrath

    2016-04-01

    Full Text Available North American Schools of Business have been “going global” by transplanting pedagogy and content to Asia and Africa for several centuries. From a teaching perspective, our western schools look to these regions as contexts to provide richness to our students’ educational experience, to prepare Americans for dealings in the global business marketplace, and often to increase our own enrollments and revenues. To date we have served as “exporters” of our own Western brand of MBA education. Using an ethnographic approach of participant observation gained through two years of teaching and living in China supplemented with interviews with Chinese students studying in the U.S., this paper suggests an alternative view. China in particular and Asia in general present a different viewpoint of leadership, motivation, team-work and MBA education in general. The paper suggests an alternative viewpoint to higher education and a series of concepts and ideas that can be “imported” into western business education from the Middle Kingdom.

  16. Estudo do impacto de um curso MBA Gestão em Saúde na modernidade organizacional de clínicas oftalmológicas Study of the impact of a MBA Administration in Health course on the organizational modernity of ophthalmologic clinics

    Directory of Open Access Journals (Sweden)

    Manuel Meireles

    2005-12-01

    Full Text Available OBJETIVO: Pesquisa no campo da aprendizagem de competências que busca investigar o impacto da aquisição de novas competências individuais dos responsáveis de clínicas oftalmológicas, por meio de um curso MBA Gestão em Saúde, na modernidade organizacional de clínicas oftalmológicas. MÉTODOS: Levantamento utilizando questionários aplicados a alunos e ex-alunos do curso e a gestores de clínicas oftalmológicas não vinculados ao curso (n=30 cada um. A análise foi feita por meio de métodos estatísticos: r de Pearson e Q de Yule; testes t de Student, da soma de séries, da mediana e teste U de Mann-Whitney. RESULTADOS: Observou-se correlação linear e positiva entre a excelência do MBA Gestão em Saúde e o desenvolvimento de capacidades dos alunos veteranos (correlação rho de Spearman em nível de 0,01; há diferença significativa (0,0364, pelo teste de Mann-Whitney, entre alunos veteranos e alunos calouros, quanto à necessidade de se ampliar as capacidades individuais que o curso MBA Gestão em Saúde fornece, aos demais funcionários operacionais das clínica oftalmológicas; e há diferença significativa (0,0057, pelo teste de Mann-Whitney, entre alunos veteranos do curso MBA Gestão em Saúde e alunos calouros quanto à importância da modernidade organizacional para as clínicas oftalmológicas. CONCLUSÕES: Os resultados obtidos são consistentes, de forma geral, com o modelo proposto: a excelência do MBA Gestão em Saúde contribui significativamente para a modernidade organizacional, para o desenvolvimento de competências dos alunos egressos e ainda de forma substancial para a percepção de hiatos organizacionais.PURPOSE: Investigations in the field of the learning competence that investigate the impact of the acquisition of new individual competence of those responsible for ophthalmologic clinics, by means of a MBA Administration in Health course, on the organizational modernity of ophthalmologic clinics. METHODS

  17. MBA theory and application of business and management principles

    CERN Document Server

    Davim, J

    2016-01-01

    This book focuses on the relevant subjects in the curriculum of an MBA program. Covering many different fields within business, this book is ideal for readers who want to prepare for a Master of Business Administration degree. It provides discussions and exchanges of information on principles, strategies, models, techniques, methodologies and applications in the business area.

  18. A Portrait of the Early 21st Century MBA

    Science.gov (United States)

    Matthews, Robert J.

    2012-01-01

    Students invest a great deal of time, effort, and capital to obtain the MBA credential that they believe will provide them with the skills necessary to succeed in business. They expect such skills to position them for better job opportunities, salary increases, and a faster track to promotion up the corporate ladder. It is an investment that…

  19. „Knowledge is power“: Studium MBA v perspektivě Bourdieuho teorie kapitálů/ “Knowledge is power”: MBA study program in Bourdieu’s perspective of capitals

    Directory of Open Access Journals (Sweden)

    Jana Dvořáčková

    2015-01-01

    Full Text Available Cílem této empirické studie, která vychází z ročního etnografického výzkumu na soukromé vysoké škole, je analyzovat, jaký význam má studijní program MBA v reprodukci sociálních diferencí. V první části je představeno teoretické pozadí studie, jímž jsou Bourdieuho koncepty kulturního, ekonomického, symbolického a sociálního kapitálu a jeho pojetí mechanismu sociální reprodukce skrze školské instituce. Druhá část příspěvku přibližuje klíčové rysy soukromé vysoké školy, kde se výzkum realizoval. Třetí část je věnována analýze manifestních cílů MBA programu, jímž je posílit kulturní a ekonomický kapitál studujících – rozvíjet jejich znalosti, kariérní perspektivy i úspěchy v podnikání. Vedle toho se zabývá MBA studiem coby zdrojem symbolického i sociálního kapitálu. Jak text ukazuje, MBA program je vedle prostředku získávání znalostí a dovedností současně prostorem konverze ekonomického kapitálu do kapitálu symbolického a sociálního. Ty následně zvyšují objem ekonomického kapitálu studujících, čímž dále upevňují jejich sociální pozici.

  20. Integration and Exchange: How Executive MBA Students Envision Ethics Education

    Science.gov (United States)

    Gruber, Verena; Schlegelmilch, Bodo B.

    2013-01-01

    Ethics education provided by universities in general, and MBA programs aimed at future business leaders in particular, has come under intense public scrutiny because of corporate scandals and ethical dilemmas. To date, academic research has been mainly devoted to the characteristics of instruction formats and their effectiveness, characteristics…

  1. Operations Management in the Design and Execution of MBA Programs

    Science.gov (United States)

    Busing, Michael E.; Palocsay, Susan W.

    2016-01-01

    Master of business administration (MBA) programs are under intense pressure to improve efficiencies, lower tuition, and offer refreshed curriculum that is of high quality and regarded as relevant by the marketplace. In light of this environment, the authors propose a conceptual framework for effectively employing operations management (OM)…

  2. Standardization of 137mCs+137mBa by Liquid Scintillation; Calibracion de 137Cs+137mBa por Centelleo Liquido

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, L.; Los Arcos, J.M.; Grau, A.

    1995-07-01

    A procedure for the preparation of a stable, homogeneous solution of 137Cs+''137mBa, for use in liquid scintillation measurements, is described. Its count rate stability and spectral time evolution has been followed for several weeks. The solution has been standardised by the CIEMAT/NIST method in both Ultima-Gold and Insta-Gel, to a combined uncertainty lower than 0,51 % (k=l). (Author) 5 refs.

  3. The discovery of 260Md and the decay properties of 258Fm, 258m,gMd and 259Md

    International Nuclear Information System (INIS)

    Lougheed, R.W.; Hulet, E.K.; Dougan, R.J.; Wild, J.F.; Dupzyk, R.J.; Henderson, C.M.; Moody, K.J.; Hahn, R.L.; Suemmerer, K.; Bethune, G.

    1986-01-01

    We have discovered a new neutron-rich isotope, 260 Md, from 18 O and 22 Ne bombardments of 254 Es. We observed a spontaneous-fission (SF) activity with a half-life of 32 days in electromagnetically separated fractions with mass number 260 from these bombardments and we measured the mass and kinetic energy distributions of this SF activity. The mass distribution was symmetric with the principal energy peak at a total kinetic energy (TKE) of 234 MeV, similar to previous observations for heavy fermium isotopes. Surprisingly, we also observed a smaller symmetric component with a TKE of 195 MeV. We interpret these two peaks in the TKE distribution as arising from two types of fission in the same nucleus, or bimodal fission. The observed fission activity may be either from the SF decay of 260 Md or from 260 Fm which would arise from electron-capture (EC) decay of 260 Md. We have eliminated the possible β - decay of 260 Md by measuring β - -SF time correlations for the decay of 260 Md and we plan to determine whether 260 Md decays by EC by measuring time correlations between fermium X-rays and SF events. We also measured various properties of the heavy fermium and mendelevium isotopes and obtained 1. more accurate cross-sections for the neutron-rich mendelevium isotopes which we use to predict the production rates of yet undiscovered nuclides, 2. improved half-life measurements for 258m,g Md and 259 Md, 3. confirmation of the EC decay of 258m Md by measurement of the fermium X-rays preceding the SF decay of 258 Fm and 4. very substantially improved mass and TKE distributions for the SF decay of 258 Fm and 259 Md. (orig.)

  4. Attitudinal Belief on Adoption of e-MBA Program in Malaysia

    Science.gov (United States)

    Mahmod, Razmah; Dahlan, Noornina; Ramayah, T.; Karia, Noorliza; Asaari, Muhammad Hasmi Abu Hassan

    2005-01-01

    E-learning describes the use of information communications technology for learning beyond the boundaries of the conventional classroom. The objective of this paper is to determine what are the factors that are significant in explaining intention towards e-learning, particularly e-MBA adoption in Malaysia. Results indicated that trialability and…

  5. Understanding MBA Consumer Needs and the Development of Marketing Strategy

    Science.gov (United States)

    Dailey, Lynn; Anderson, Murphy; Ingenito, Cristina; Duffy, David; Krimm, Paul; Thomson, Scott

    2006-01-01

    The need to develop marketing strategies in higher education is evident. In order to develop effective strategies, marketers must understand the basic needs that their product fulfills. Exploratory research was utilized to identify and better understand the needs that motivate consumers to pursue an MBA degree. This paper emphasizes the importance…

  6. [Study of the impact of a MBA Administration in Health course on the organizational modernity of ophthalmologic clinics].

    Science.gov (United States)

    Meireles, Manuel; Scarpi, Marinho Jorge

    2005-01-01

    Investigations in the field of the learning competence that investigate the impact of the acquisition of new individual competence of those responsible for ophthalmologic clinics, by means of a MBA Administration in Health course, on the organizational modernity of ophthalmologic clinics. Survey using questionnaires applied to students and former students of the course and to managers of ophthalmologic clinics not linked to the course (n=30 each one). The analysis was made by means of statistical methods: r of Pearson and Q of Yule; Student's t test, sum of series test, median test and U test of Mann-Whitney. Linear and positive correlation was observed between excellency of MBA Administration in Health and the development of the veteran students' capacities (rho correlation of Spearman at the level of 0.01); there is a significant difference (0.0364, by the Mann-Whitney test), between veteran students and freshmen regarding the need to extend the individual capacities provided by the MBA Administration in Health course, to the other operational employees of the ophthalmologic clinics; and there is a significant difference (0.0057, for the Mann-Whitney test), among veteran students of the MBA Administration in Health course and freshmen regarding the importance of the organizational modernity for the ophthalmologic clinics. The obtained results are consistent, in a general way, with the proposed model: MBA Administration's excellence in Health contributes significantly to the organizational modernity, to the development of competence of the veteran students, and, also in substantial way to the perception of organizational hiatuses.

  7. MD-11 PCA - Closeup view of aircraft on ramp

    Science.gov (United States)

    1995-01-01

    This McDonnell Douglas MD-11 has taxied to a position on the flightline at NASA's Dryden Flight Research Center, Edwards, California, following its completion of the first and second landings ever performed by a transport aircraft under engine power only (on Aug. 29, 1995). The milestone flight, with NASA research pilot and former astronaut Gordon Fullerton at the controls, was part of a NASA project to develop a computer-assisted engine control system that enables a pilot to land a plane safely when its normal control surfaces are disabled. The Propulsion-Controlled Aircraft (PCA) system uses standard autopilot controls already present in the cockpit, together with the new programming in the aircraft's flight control computers. The PCA concept is simple. For pitch control, the program increases thrust to climb and reduces thrust to descend. To turn right, the autopilot increases the left engine thrust while decreasing the right engine thrust. The initial Propulsion-Controlled Aircraft studies by NASA were carried out at Dryden with a modified twin-engine F-15 research aircraft.

  8. Edward Hopper: The Watercolors.

    Science.gov (United States)

    Johnson, Mark M.

    2000-01-01

    Provides information on Edward Hopper, focusing on his use of watercolors. Explores five of his watercolor paintings: (1) "The Mansard Roof"; (2) "House on Pamet River"; (3) "Light at Two Lights"; (4) "Saltillo Mansion"; and (5) "Roofs of Washington Square." Addresses the exhibition "Edward…

  9. Proposal for Supply Chain Concentration in the Traditional MBA Program

    Science.gov (United States)

    Ramaswamy, K. V.

    2012-01-01

    The purpose of this proposal is to develop and implement a concentration in Supply Chain Management in the existing traditional MBA program effective fall 2012. Houston is the hub for many multinational oil and energy companies, large healthcare systems, wholesale/retail businesses, engineering and construction companies, and is a major city along…

  10. Self-Reporting MBA Key Experience Assessment: Evidence from Lincoln University

    Science.gov (United States)

    Tailab, Mohamed; Guerra, Michael

    2017-01-01

    This paper empirically provides an innovative way of thinking about the MBA program at Lincoln University (hereafter LU) by giving students an opportunity to rate their work experience based on how they currently see themselves. This manuscript develops the instrument prepared by McMillan & Hearn (2004) by creating a questionnaire including 21…

  11. Biological survey of the Prince Edward Islands, December 2008

    Directory of Open Access Journals (Sweden)

    P.G. Ryan

    2010-01-01

    Full Text Available A biological survey of the Prince Edward Islands took place in December 2008. The survey repeated an earlier survey of the populations of surface-nesting seabirds on both islands and of fur seals (Arctocephalus spp. and alien plants on Prince Edward Island in December 2001. Observations on burrowing seabirds, macro-invertebrates and plant communities on Prince Edward Island and an oceanographic survey of surrounding waters were also included. The survey confirmed many of the observations made on the earlier survey and permitted an assessment of trends in the abundance and distribution of biota since 2001.

  12. The Fast Forward MBA in Project Management

    CERN Document Server

    Verzuh, Eric

    2011-01-01

    An updated and revised edition of the bestselling guide to managing projects For any professional responsible for coordinating projects among different departments, across executive levels, or with technical complexity, The Fast Forward MBA in Project Management offers comprehensive instruction on how to deliver on time and on budget. Get the step-by-step advice you need to find the right sponsor, clarify objectives, and set realistic schedules and budget projections. This Fourth Edition of the 200,000-copy bestseller now covers critical new topics including: software and IT projects, agile te

  13. Deep Learning through Reusable Learning Objects in an MBA Program

    Science.gov (United States)

    Rufer, Rosalyn; Adams, Ruifang Hope

    2013-01-01

    It has well been established that it is important to be able to leverage any organization's processes and core competencies to sustain its competitive advantage. Thus, one learning objective of an online MBA is to teach students how to apply the VRIO (value, rarity, inimitable, operationalized) model, developed by Barney and Hesterly (2006), in…

  14. An Exploratory Study on the Application of Multiple Intelligences to MBA Andragogy with Particular Reference to ERP-Controlling Configuration Course

    Science.gov (United States)

    Gaikwad, Sophia S.; Bharathi, S. Vijayakumar

    2018-01-01

    The purpose of this study is to elicit the application of Multiple Intelligences (MI) theory to a course taught in the MBA Andragogy. Administered to a sample of 47 students of the first year MBA Information Technology Business Management (ITBM) program at a private university in India the study brought out certain interesting implications.…

  15. Md Naimuddin

    Indian Academy of Sciences (India)

    Home; Journals; Pramana – Journal of Physics. Md Naimuddin. Articles written in Pramana – Journal of Physics. Volume 79 Issue 5 November 2012 pp 1255-1258 Poster Presentations. Model unspecific search for new physics in collision at s = 7 TeV · Shivali Malhotra Md Naimuddin Thomas Hebbeker Arnd Meyer ...

  16. Üleilmastumisel on linna nägu / Edward W. Soja ; interv. Karin Paulus

    Index Scriptorium Estoniae

    Soja, Edward W.

    2008-01-01

    Ameerika linnageograaf Edward W. Soja räägib globaliseerumisest, linnastumisest, rikkuse ebaühtlasest jaotumisest, subkultuuridest, inimese identiteedi muutumisest, raamatust "Thirdspace". Lühidalt Edward W. Soja tegevusest, foto. Lisa: Kes on Edward W. Soja?

  17. Poly(AAc-co-MBA) hydrogel films: adhesive and mechanical properties in aqueous medium.

    Science.gov (United States)

    Arunbabu, Dhamodaran; Shahsavan, Hamed; Zhang, Wei; Zhao, Boxin

    2013-01-10

    Poly(acrylic acid-co-N,N'-methylenebisacrylamide) hydrogel films were synthesized by copolymerizing acrylic acid (AAc) with N,N'-methylenebisacrylamide (MBA) as a cross-linker via photo polymerization in the spacing confined between two glass plates. NMR spectroscopy was utilized to determine the cross-linking density. We found that the cross-linking density determined by NMR is higher than that expected from the feed concentrations of cross-linkers, suggesting that MBA is more reactive than AAc and the heterogeneous nature of the cross-linking. In addition to the swelling tests, indentation tests were performed on the hydrogel films under water to investigate effects of the cross-linking density on the adhesion and mechanical properties of the hydrogel films in terms of adhesive pull-off force and Hertz-type elastic modulus. As the cross-linker concentration increased, the effective elastic modulus of the hydrogel films increased dramatically at low cross-linking densities and reached a high steady-state value at higher cross-linking densities. The pull-off force decreased with increasing cross-linker concentration and reached a lower force plateau at high cross-linking densities. An optimal "trade-off" cross-linking density was determined to be 0.02 mol fraction of MBA in the hydrogel, where balanced elastic modulus and adhesive pull-off force can be obtained.

  18. Interpersonal Skills in MBA Admissions: How Are They Conceptualized and Assessed?

    Science.gov (United States)

    Beenen, Gerard; Pichler, Shaun; Davoudpour, Shahin

    2018-01-01

    Employers and students concur that soft skills or interpersonal skills are critical to managerial success, yet we know little about how MBA program admissions professionals conceptualize and assess these skills in the context of global management education. Such practices have key implications for interpersonal skills curriculum and training in…

  19. MicroED Structure of Au146(p-MBA)57 at Subatomic Resolution Reveals a Twinned FCC Cluster.

    Science.gov (United States)

    Vergara, Sandra; Lukes, Dylan A; Martynowycz, Michael W; Santiago, Ulises; Plascencia-Villa, Germán; Weiss, Simon C; de la Cruz, M Jason; Black, David M; Alvarez, Marcos M; López-Lozano, Xochitl; Barnes, Christopher O; Lin, Guowu; Weissker, Hans-Christian; Whetten, Robert L; Gonen, Tamir; Yacaman, Miguel Jose; Calero, Guillermo

    2017-11-16

    Solving the atomic structure of metallic clusters is fundamental to understanding their optical, electronic, and chemical properties. Herein we present the structure of the largest aqueous gold cluster, Au 146 (p-MBA) 57 (p-MBA: para-mercaptobenzoic acid), solved by electron micro-diffraction (MicroED) to subatomic resolution (0.85 Å) and by X-ray diffraction at atomic resolution (1.3 Å). The 146 gold atoms may be decomposed into two constituent sets consisting of 119 core and 27 peripheral atoms. The core atoms are organized in a twinned FCC structure, whereas the surface gold atoms follow a C 2 rotational symmetry about an axis bisecting the twinning plane. The protective layer of 57 p-MBAs fully encloses the cluster and comprises bridging, monomeric, and dimeric staple motifs. Au 146 (p-MBA) 57 is the largest cluster observed exhibiting a bulk-like FCC structure as well as the smallest gold particle exhibiting a stacking fault.

  20. Apple fruit acidity is genetically diversified by natural variations in three hierarchical epistatic genes MdSAUR37, MdPP2CH and MdALMTII.

    Science.gov (United States)

    Jia, Dongjie; Shen, Fei; Wang, Yi; Wu, Ting; Xu, Xuefeng; Zhang, Xinzhong; Han, Zhenhai

    2018-05-11

    Many efforts have been made to map quantitative trait loci (QTLs) to facilitate practical marker-assisted selection (MAS) in plants. In the present study, we identified four genome-wide major QTLs responsible for apple fruit acidity by MapQTL and BSA-seq analyses using two independent pedigree-based populations. Candidate genes were screened in major QTL regions, and three functional gene markers, including a non-synonymous A/G single nucleotide polymorphism (SNP) in the coding region of MdPP2CH, a 36-bp insertion in the promoter of MdSAUR37, and a previously reported SNP in MdALMTII, were validated to influence the malate content of apple fruits. In addition, MdPP2CH inactivated three vacuolar H + -ATPases (MdVHA-A3, MdVHA-B2 and MdVHA-D2) and one aluminium-activated malate transporter (MdALMTII) via dephosphorylation and negatively influenced fruit malate accumulation. The dephosphotase activity of MdPP2CH was suppressed by MdSAUR37, which implied a higher hierarchy of genetic interaction. Therefore, the MdSAUR37/MdPP2CH/MdALMTII chain cascaded hierarchical epistatic genetic effects to precisely determine apple fruit malate content. An A/G SNP (-1010) on MdMYB44 promoter region from a major QTL (qtl08.1) was closely associated with fruit malate content. The predicted phenotype values (PPVs) were estimated using the tentative genotype values of the gene markers, and the PPVs were significantly correlated with the observed phenotype values. Our findings provide an insight into plant genome-based selection in apples and will aid in conducting research to understand the physiological fundamentals of quantitative genetics. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  1. Evaluation of inventory change report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B

    International Nuclear Information System (INIS)

    Agustinus Suprijanto; Suratno; Sigit Pramana

    2013-01-01

    Evaluation has been performed for Inventory Change Report (ICR) in 2008/2009 - 2012/2013 in MBA.RI-B (MBA = Material Balance Area) (RI-B = Center for Accelerator and Material Process Technology). The evaluation performed on the inventory change report of nuclear material document. Changes in inventories occur when there is acceptance or shipment of nuclear materials outside nuclear facilities. Successive reports changes in inventory of nuclear material in 2008/2009 comprised 3 sheets ICR document numbers (153, 154 and 155), in 2009/2010 comprised 1 sheet ICR document number (159), in 2010/2011 comprised 3 sheets ICR document numbers (164, 165 and 166), and in 2012/2013 comprised 2 sheets ICR document numbers (175 and 176). From these data report changes in inventory of nuclear material can be concluded that in MBA.RI-B has been the displacement of nuclear material activities includes receipt of nuclear material from other nuclear facilities and shipments of nuclear materials out of facilities for research and development includes receipt 4 times from RI-E and 1 times from RI-A and 3 times shipment to RI-E. (author)

  2. Designing and Using Projects with Real World Application in a MBA Managerial Accounting Class: The Case of The Balanced Scorecard

    Science.gov (United States)

    Houke, Charlotte

    2017-01-01

    This paper explores the purpose of designing and using projects with real world application in a M.B.A. managerial accounting class. Included is a discussion of how and why the Balanced Scorecard (BSC) Project has been used in classes to link theory with practice by providing real world application of the BSC framework. M.B.A. students represent a…

  3. Injector MD Days 2017

    CERN Document Server

    Rumolo, G

    2017-01-01

    The Injector Machine Development (MD) days 2017 were held on 23-24 March, 2017, at CERN with thefollowing main goals:Give a chance to the MD users to present their results and show the relevant progress made in 2016 onseveral fronts.Provide the MD users and the Operation (OP) crews with a general overview on the outcome and theimpact of all ongoing MD activities.Identify the open questions and consequently define - with priorities - a list of machine studies in theinjectors for 2017 (covering the operational beams, LHC Injectors Upgrade, High Luminosity LHC,Physics Beyond Colliders, other projects).Create the opportunity to collect and document the highlights of the 2016 MDs and define the perspectivesfor 2017.Discuss how to make best use of the MD time, in particular let the main MD user express their wishesand see whether/how OP teams can contribute to their fulfilment.

  4. Edward Said and "Orientalism"

    Science.gov (United States)

    Chronicle of Higher Education, 2007

    2007-01-01

    In the nearly 30 years since Edward Said published the hugely influential Orientalism, his indictment of racism and imperialism in Western scholarship on the Orient has had its share of plaudits and condemnations. Now Robert Irwin, the Middle East editor of The Times Literary Supplement, has reignited the controversy with his broadside against the…

  5. 'Food for thought': New MBA with focus on the food sector at Aarhus School of Business

    DEFF Research Database (Denmark)

    Stacey, Julia; Brunsø, Karen; Andersen, Lone Schreiber

    2002-01-01

    During the autumn of 2002, Aarhus School of Business decided to launch a new international MBA - with focus on the food sector. Prior to this decision lay thorough groundwork in the shape of a positive demand study among the largest food companies in Denmark, Sweden, Norway and Finland. The concl......During the autumn of 2002, Aarhus School of Business decided to launch a new international MBA - with focus on the food sector. Prior to this decision lay thorough groundwork in the shape of a positive demand study among the largest food companies in Denmark, Sweden, Norway and Finland...

  6. Concrete Steps for Assessing the "Soft Skills" in an MBA Program

    Science.gov (United States)

    Ingols, Cynthia; Shapiro, Mary

    2014-01-01

    In 2006, our School of Management began the serious path of assessing both the "hard skills" (such as accounting, finance, and strategy) and the "soft skills" (such as leadership, team work, and ethics) of our MBA Program. The data generated from examining the "soft skills" that we want students to learn within our…

  7. Exploring intentions of physician-scientist trainees: factors influencing MD and MD/PhD interest in research careers.

    Science.gov (United States)

    Kwan, Jennifer M; Daye, Dania; Schmidt, Mary Lou; Conlon, Claudia Morrissey; Kim, Hajwa; Gaonkar, Bilwaj; Payne, Aimee S; Riddle, Megan; Madera, Sharline; Adami, Alexander J; Winter, Kate Quinn

    2017-07-11

    Prior studies have described the career paths of physician-scientist candidates after graduation, but the factors that influence career choices at the candidate stage remain unclear. Additionally, previous work has focused on MD/PhDs, despite many physician-scientists being MDs. This study sought to identify career sector intentions, important factors in career selection, and experienced and predicted obstacles to career success that influence the career choices of MD candidates, MD candidates with research-intense career intentions (MD-RI), and MD/PhD candidates. A 70-question survey was administered to students at 5 academic medical centers with Medical Scientist Training Programs (MSTPs) and Clinical and Translational Science Awards (CTSA) from the NIH. Data were analyzed using bivariate or multivariate analyses. More MD/PhD and MD-RI candidates anticipated or had experienced obstacles related to balancing academic and family responsibilities and to balancing clinical, research, and education responsibilities, whereas more MD candidates indicated experienced and predicted obstacles related to loan repayment. MD/PhD candidates expressed higher interest in basic and translational research compared to MD-RI candidates, who indicated more interest in clinical research. Overall, MD-RI candidates displayed a profile distinct from both MD/PhD and MD candidates. MD/PhD and MD-RI candidates experience obstacles that influence their intentions to pursue academic medical careers from the earliest training stage, obstacles which differ from those of their MD peers. The differences between the aspirations of and challenges facing MD, MD-RI and MD/PhD candidates present opportunities for training programs to target curricula and support services to ensure the career development of successful physician-scientists.

  8. Impact of a dual PharmD/MBA degree on graduates' academic performance, career opportunities, and earning potential.

    Science.gov (United States)

    Chumney, Elinor C G; Ragucci, Kelly R; Jones, Kathy J

    2008-04-15

    To evaluate the academic experience and satisfaction of students who completed a dual PharmD/MBA degree program and the program's long-term impact on the students' career choice and earning potential. GPAs, job placement, and starting job salaries were compared between graduates who completed the dual PharmD/MBA program and those who completed only the PharmD program. A satisfaction survey instrument was administered to 17 students who completed the dual PharmD/MBA degree program in May 2007. Data from a standardized job placement and starting salary survey instrument completed by all PharmD graduates were also obtained, as well as all students' final grade point averages (GPAs). GPAs, job placement, and starting job salaries were compared between graduates who had completed the dual PharmD/MBA program and those who had completed only the PharmD program. The graduating GPAs of dual-degree students were higher than those of both pharmacy (3.52 vs 3.41, p > 0.10) and business (3.82 vs. 3.68, p = 0.018) students not enrolled in the dual-degree program. Dual-degree students were slightly less likely to enter a residency (17% vs. 27%, p = 0.44) than other pharmacy graduates. Among those who elected not to pursue a residency, both mean starting salaries ($111,090 vs. $101,965) and mean total first-year compensation ($127,290 vs. $110,388) were significantly higher for dual-degree graduates compared to the PharmD graduates. Students enrolled in the dual-degree program did slightly better academically than students who completed only the MBA or PharmD programs and indicated a high level of satisfaction with the program. Dual-degree graduates reported increased career opportunities and were slated to earn significantly more during their first year in the workforce. These results affirm continuation of our program and make the case for support of similar programs across the nation.

  9. Cryptanalysis of MD2

    DEFF Research Database (Denmark)

    Knudsen, Lars Ramkilde; Mathiassen, John Erik; Muller, Frédéric

    2010-01-01

    This paper considers the hash function MD2 which was developed by Ron Rivest in 1989. Despite its age, MD2 has withstood cryptanalytic attacks until recently. This paper contains the state-of-the-art cryptanalytic results on MD2, in particular collision and preimage attacks on the full hash...

  10. MBA Students' Workplace Writing: Implications for Business Writing Pedagogy and Workplace Practice

    Science.gov (United States)

    Lentz, Paula

    2013-01-01

    Employers frequently complain about the state of their employees' writing skills. Much of the current research on this subject explores workplace writing skills from the employer's perspective. However, this article examines workplace writing from the employees' perspective. Specifically, it analyzes MBA students' responses to a course assignment…

  11. Identification of 253Md

    International Nuclear Information System (INIS)

    Kadkhodayan, B.; Czerwinski, K.R.; Kreek, S.A.; Hannink, N.J.; Gregorich, K.E.; Lee, D.M.; Nurmia, M.J.; Hoffman, D.C.; Hall, H.L.

    1992-01-01

    We have measured the half-life and production cross section of the new isotope 253 Md, produced via the 243 Am( 13 C,3n) reaction. Isolation of Md from other activities was accomplished using elution with ammonium α-hydroxyisobutyrate from a cation exchange resin column. Experiments were performed with different irradiation time intervals, but the chemical separation always began and ended at exactly the same length of time after the end of irradiation. All separations with the same irradation lengths were combined and analyzed for growth and decay of the 3.0-d 253 Fm daughter and 20.47-d 253 Es, granddaugther of 253 Md. The amount of 253 Es in each fraction depends on the length of each irradiation and the 253 Md half-life. An increase in the length of irradiation will cause a corresponding increase in the amount of the new isotope 253 Md and hence, in the amount of 253 Es produced, provided the length of irradiations are not very long compared to the half-life of 253 Md. In this way, the Md half-life was estimated to be about 6 minutes with a production cross section of the order of 50 nb. (orig.)

  12. Aspects of Intercultural Awareness through an MBA Study Abroad Program: Going "Backstage"

    Science.gov (United States)

    Tuleja, Elizabeth A.

    2008-01-01

    Understanding the globalization of business practices is an important area of learning for students studying in master of business administration (MBA) programs today, and many graduate business programs offer study tour programs for experiential learning. This article examines the instructional design of one program and makes recommendations for…

  13. The Use of a Well-Designed Instructional Guideline in Online MBA Teaching

    Science.gov (United States)

    Duesing, Robert J.; Ling, Juan; Yang, Jiaqin

    2016-01-01

    This study investigated the positive impact of a teaching practice on student learning outcomes in an online MBA program. An instructional project guideline was developed to help online students enhance their achieving required learning objectives corresponding to five categories of Bloom's Taxonomy. The course learning objectives are based on…

  14. The labour ward analgesic service at King Edward VIII Hospital ...

    African Journals Online (AJOL)

    The labour ward analgesic service at King Edward VIII. Hospital, Durban. D. A. ROCKE, C. C. ROUT, H. D. RUSSELL, S. SINGH. Abstract The provision of analgesic services to the labour ward at King Edward VIII Hospital was studied during a I-week period. Of249 patients, 113 (45%) received no analgesia whatsoever.

  15. Edward Said on Popular Music

    NARCIS (Netherlands)

    Capitain, W.H.P.

    2017-01-01

    Although Edward Said, generally known as one of the founders of postcolonial studies, has written extensively on music, he almost completely ignores popular music. However, the few moments in which he does reflect on popular music are highly revealing. In this article I provide a comprehensive

  16. Reading Edward Said in Myanmar

    DEFF Research Database (Denmark)

    Jensen, Lars

    2014-01-01

    Twenty years after its publication, Culture and Imperialism continues to be seen as part of the defining moment of postcolonial readings of our contemporary world. The anniversary marks an opportunity to revisit the landscape of culture and imperialism as envisaged by Edward Said, but also to dis...

  17. What Do We Teach in Organizational Behavior? An Analysis of MBA Syllabi

    Science.gov (United States)

    Brown, Kenneth G.; Charlier, Steven D.; Rynes, Sara L.; Hosmanek, Andrew

    2013-01-01

    This study examines the syllabi of 241 required organizational behavior (OB) related classes in full-time U.S. MBA programs. Syllabi were coded for information about course title, topics, readings, cases, teaching methods, and learning assessment methods. Results revealed that the most frequent topics listed across courses are leadership and…

  18. MBA Program Trends and Best Practices in Teaching Sustainability: Live Project Courses

    Science.gov (United States)

    Sroufe, Robert; Ramos, Diane

    2011-01-01

    This study offers a model for incorporating live sustainability consulting projects in an MBA curriculum to nurture cross-functional faculty collaboration while offering students proving ground for solving contemporary challenges related to ethical management of all forms of capital. We attempt to first lay a foundation for the recent evolution of…

  19. MBA Effectiveness in Non-OECD Countries: Perceptions of Leadership and Managerial Skills

    Science.gov (United States)

    Gilbert, Douglas J.

    2010-01-01

    The purpose of this quantitative comparative methods research was to compare the perceptions relative to 12 Master of Business Administration (MBA) skill sets of respondents situated in non-member countries of the Organisation for Economic Cooperation and Development (OECD) with the findings of a prior study of United States situated respondents.…

  20. Experiential, Collaborative and Team Projects: Communication Audits in the MBA Communication Course

    Science.gov (United States)

    Hart, Claudia; Vroman, Margo; Stulz, Karin

    2015-01-01

    In this paper the authors discuss the challenges and rewards of building a graduate level Managerial Communication course around an experiential communication audit project. The purpose of the project was to provide MBA (Master of Business Administration) students with exposure to the real world responsibilities and demands of working in a complex…

  1. New records of Acari from the sub-Antarctic Prince Edward Islands

    NARCIS (Netherlands)

    Marshall, D.J.; Gremmen, N.J.M.; Coetzee, L.; Oconnor, B.M.; Pugh, P.J.A.; Theron, P.D.; Ueckermann, E.A.

    1999-01-01

    Sixty species of Acari are recorded from the sub-Antarctic Marion and Prince Edward Islands (the Prince Edward archipelago). Twenty of the 45 species collected on recent expeditions are new and currently undescribed. Other new taxa include a family of Mesostigmata, four new genera, and the first

  2. "One-Size-Does-Not-Fit-All": Teaching MBA Students Different ERP Implementation Strategies

    Science.gov (United States)

    Venkatesh, Viswanath

    2008-01-01

    This teaching tip discusses an approach to educating MBA students regarding strategies to select, design, and implement enterprise resource planning (ERP) systems. The teaching approach presented here discusses how to teach students about different strategies based success stories from three different organizations, namely Cisco, Tektronix, and…

  3. Auditing Communication Effectiveness in Higher Education: A Team-Based Study by MBA Students

    Science.gov (United States)

    Hart, Claudia; Plemmons, Tony; Stulz, Karin; Vroman, Margo

    2017-01-01

    A regional University in the United States implemented an AQIP (Academic Quality Improvement Program) Action Project with a goal of developing processes for effective leadership communication. An MBA (Masters of Business Administration) class conducted a university-wide communication audit to assist with the AQIP project. Quantitative and…

  4. Reflective Learning in a Chinese MBA Programme: Scale Assessment and Future Recommendations

    Science.gov (United States)

    Xiao, Qian; Zhu, Pinghui; Hsu, Maxwell K.; Zhuang, Weiling; Peltier, James

    2016-01-01

    The purpose of this study was twofold: (1) to use Chinese MBA students to validate the expanded reflective learning continuum and address the concerns raised in this regard in business education; (2) to determine whether the continuum concept holds true in a non-western culture and whether the reflective learning continuum remains a powerful force…

  5. A New Higher Education Marketing Mix: The 7Ps for MBA Marketing

    Science.gov (United States)

    Ivy, Jonathan

    2008-01-01

    Purpose: The purpose of this paper is to present a new marketing mix based on MBA students' attitudes and opinions towards the marketing initiatives of business schools in South Africa. The post-graduate business education market is, and increasingly, getting more aggressive in their efforts to attract students on to their flagship degree, the…

  6. A Romanian Jew in Hollywood: Edward G. Robinson

    Directory of Open Access Journals (Sweden)

    Moldovan Raluca

    2014-08-01

    Full Text Available The present study aims to investigate the contribution that actor Edward G. Robinson brought to the American film industry, beginning with his iconic role as gangster Little Caesar in Mervyn Le Roy’s 1931 production, and continuing with widely-acclaimed parts in classic film noirs such as Double Indemnity, The Woman in the Window and Scarlet Street. Edward G. Robinson was actually a Romanian Jew, born Emmanuel Goldenberg in Bucharest, in 1893, a relatively little known fact nowadays. By examining his biography, filmography and his best-known, most successful films (mentioned above, I show that Edward G. Robinson was one of classical Hollywood’s most influential actors; for instance, traits of his portrayal of Little Caesar (one of the very first American gangster films can be found in almost all subsequent cinematic gangster figures, from Scarface to Vito Corleone. In the same vein, the doomed noir characters he played in Fritz Lang’s The Woman in the Window and Scarlet Street are still considered by film critics today to be some of the finest, most nuanced examples of noir heroes. Therefore, the main body of my article will be dedicated to a more detailed analysis of these films, while the introductory section will trace his biography and discuss some of his better-known films, such as Confessions of a Nazi Spy and Key Largo. The present study highlights Edward G. Robinson’s merits and impact on the cinema industry, proving that this diminutive Romanian Jew of humble origins was indeed something of a giant during Hollywood’s classical era.

  7. A Test of the Teaching-Learning Style Mesh Hypothesis in a Chinese MBA

    Science.gov (United States)

    Andres, Hayward P.; Akan, Obasi H.

    2015-01-01

    Purpose: The purpose of this paper is to determine if "fit" and "non-fit" between authoritarian versus demonstrator teaching and visual versus verbal learning preferences differ in impact on Chinese MBA student academic performance in a large local urban Chinese university setting. In addition, the role of Chinese cultural…

  8. MBA in Education Leadership: A Model for Developing an Interdisciplinary Principal Preparation Program

    Science.gov (United States)

    Smith, Rachel A.; Somers, John

    2016-01-01

    This paper presents a model for developing an interdisciplinary principal preparation program, an MBA in Education Leadership, which integrates best practices in both education and business within an educational context. The paper addresses gaps that exist in many traditional principal preparation programs and provides an alternative model, which…

  9. Using Media Articles about Company Strategies to Teach Economics to MBA Students

    Science.gov (United States)

    Ghosh, Indranil K.

    2012-01-01

    In this paper, the author expands on the idea of using up-to-date examples to teach applications of economic concepts. In the MBA Managerial Economics class, the author use profiles of two companies' decision-making strategies and their successes to show the applications of economic concepts used by the companies. This provides an even clearer…

  10. Management Communication in Non-U.S. MBA Programs: Current Trends and Practices

    Science.gov (United States)

    Knight, Melinda

    2005-01-01

    A study of top-ranked, full-time, global MBA programs suggests that management communication is indeed both an important focus and component in the curriculum. The methods of delivery, however, do not seem to follow any particular model, such as the common U.S. practice of a separate program or department. Required courses are found at 10 of the…

  11. A Process for Assessing and Improving Business Writing at the MBA Level

    Science.gov (United States)

    May, Gary L.; Thompson, Margaret A.; Hebblethwaite, Jennifer

    2012-01-01

    Assurance of learning continues to be a hot topic in higher education. Both accreditation agencies and employers are asking a key question: Are we graduating students who actually have the knowledge and skills that we promise? This case study focuses on business writing in an MBA program and presents a prescriptive, five-step program to improve…

  12. A Study of Distress, Wellness and Organisational Role Stress among MBA Professionals

    Science.gov (United States)

    Kumar, Rajender

    2011-01-01

    The purpose of this research was to study Distress, Wellness and Organisational role stress of MBA professionals in the area of various companies and industries of Haryana. The effect of sex and age on the above variables were examined. Total 101 professionals (60 men and 41 women) were administered for the study. General Health Questionnaire-28…

  13. Apple (Malus domestica) MdERF2 negatively affects ethylene biosynthesis during fruit ripening by suppressing MdACS1 transcription.

    Science.gov (United States)

    Li, Tong; Jiang, Zhongyu; Zhang, Lichao; Tan, Dongmei; Wei, Yun; Yuan, Hui; Li, Tianlai; Wang, Aide

    2016-12-01

    Ripening in climacteric fruit requires the gaseous phytohormone ethylene. Although ethylene signaling has been well studied, knowledge of the transcriptional regulation of ethylene biosynthesis is still limited. Here we show that an apple (Malus domestica) ethylene response factor, MdERF2, negatively affects ethylene biosynthesis and fruit ripening by suppressing the transcription of MdACS1, a gene that is critical for biosynthesis of ripening-related ethylene. Expression of MdERF2 was suppressed by ethylene during ripening of apple fruit, and we observed that MdERF2 bound to the promoter of MdACS1 and directly suppressed its transcription. Moreover, MdERF2 suppressed the activity of the promoter of MdERF3, a transcription factor that we found to bind to the MdACS1 promoter, thereby increasing MdACS1 transcription. We determined that the MdERF2 and MdERF3 proteins directly interact, and this interaction suppresses the binding of MdERF3 to the MdACS1 promoter. Moreover, apple fruit with transiently downregulated MdERF2 expression showed higher ethylene production and faster ripening. Our results indicate that MdERF2 negatively affects ethylene biosynthesis and fruit ripening in apple by suppressing the transcription of MdACS1 via multiple mechanisms, thereby acting as an antagonist of positive ripening regulators. Our findings offer a deep understanding of the transcriptional regulation of ethylene biosynthesis during climacteric fruit ripening. © 2016 The Authors The Plant Journal © 2016 John Wiley & Sons Ltd.

  14. The International Market for MBA Qualifications: The Relationship between Tuition Fees and Applications

    Science.gov (United States)

    Elliott, Caroline; Soo, Kwok Tong

    2013-01-01

    This paper explores the relationship between tuition fees charged by MBA programmes and the number of applications to these programmes, using a panel dataset comprising universities from countries across the world. Using Three-Stage-Least-Squares methods for simultaneous equations, we find a two-way relationship between tuition fees and…

  15. Standardization of 137mCs+137mBa by Liquid Scintillation

    International Nuclear Information System (INIS)

    Rodriguez, L.; Los Arcos, J.M.; Grau, A.

    1995-01-01

    A procedure for the preparation of a stable, homogeneous solution of 137Cs+''137mBa, for use in liquid scintillation measurements, is described. Its count rate stability and spectral time evolution has been followed for several weeks. The solution has been standardised by the CIEMAT/NIST method in both Ultima-Gold and Insta-Gel, to a combined uncertainty lower than 0,51 % (k=l). (Author) 5 refs

  16. Innovating in health care management education: development of an accelerated MBA and MPH degree program at Yale.

    Science.gov (United States)

    Pettigrew, Melinda M; Forman, Howard P; Pistell, Anne F; Nembhard, Ingrid M

    2015-03-01

    Increasingly, there is recognition of the need for individuals with expertise in both management and public health to help health care organizations deliver high-quality and cost-effective care. The Yale School of Public Health and Yale School of Management began offering an accelerated Master of Business Administration (MBA) and Master of Public Health (MPH) joint degree program in the summer of 2014. This new program enables students to earn MBA and MPH degrees simultaneously from 2 fully accredited schools in 22 months. Students will graduate with the knowledge and skills needed to become innovative leaders of health care organizations. We discuss the rationale for the program, the developmental process, the curriculum, benefits of the program, and potential challenges.

  17. A Business Communication Module for an MBA "Managerial Accounting" Course: A Teaching Note

    Science.gov (United States)

    Stout, David E.

    2014-01-01

    This Teaching Note describes a two-hour-and-40-minute "Business Communication" module developed and used by the author over the past six years in an MBA "Managerial Accounting" course at a university in the USA. The module has two modest but important goals: to sensitize graduate accounting students to the importance of…

  18. An Alternative Approach for MBA Mentor Programs: Empower the Protégé

    Science.gov (United States)

    Artis, Andrew B.

    2013-01-01

    A new approach is proposed to maximize the benefits of mentor relationships between master of business administration (MBA) students and executives by empowering students to select and recruit their own mentors, and then be responsible for managing those relationships. This mentor program is designed to be short but intensive. First-year MBA…

  19. Challenges Faced by Graduate Business Education in Southern Africa: Perceptions of MBA Participants

    Science.gov (United States)

    Temtime, Zelealem T.; Mmereki, Rebana N.

    2011-01-01

    Purpose: The purpose of this paper is to examine the degree of satisfaction and perceived relevance of the Graduate Business Education (GBE) programme at the University of Botswana. Design/methodology/approach: A self-administered questionnaire and face to face interviews were used to collect data from Master of Business Administration (MBA)…

  20. Using Student Input to Develop a Marketing Strategy for an Executive MBA Program

    Science.gov (United States)

    Geissler, Gary L.

    2011-01-01

    Despite continued growth in the number of Executive MBA (EMBA) Programs in the U. S. and worldwide, previous research concerning the marketing of EMBA Programs has been very limited. Here, the author investigates ways to successfully market an EMBA Program at a southern U. S. university. Extensive exploratory research was conducted among current…

  1. Prince Edward Island's School Psychology Report

    Science.gov (United States)

    Matters, Rhonda

    2016-01-01

    The Prince Edward Island (PEI) school system has been struggling with issues of recruitment and particularly retention for psychologists. Reasons include concerns about professional autonomy; having more limited roles, which are heavily assessment focused; reduced job satisfaction; and restrictions on additional private practice work. The waiting…

  2. van den Heuvel, Prof. Edward P J

    Indian Academy of Sciences (India)

    van den Heuvel, Prof. Edward P J . Date of birth: 2 November 1940. Address: Professor of Astrophysics, Astronomical Inst. Anton Pannekoek, Postbus 94249, 1090 GE Amsterdam, The Netherlands Contact: Office: (+31-20) 525 ...

  3. The GMAT as a Predictor of MBA Performance: Less Success than Meets the Eye

    Science.gov (United States)

    Kass, Darrin; Grandzol, Christian; Bommer, William

    2012-01-01

    Consistent with previous research, the authors found that the combined use of undergraduate grade point average and the Graduate Management Admission Test (GMAT) verbal and quantitative sections successfully predicted performance in a master of business administration (MBA) program. However, these measures did not successfully predict the…

  4. An Assessment of Demand for a Combined PharmD-MBA Program at the University of Saskatchewan.

    Science.gov (United States)

    Mansell, Kerry; Bruneau-Bouchard, Antoine; Bruni-Bossio, Vincent

    2016-05-13

    (1) Background: Combined MBA programs are becoming increasingly popular, and it is anticipated that there will be 60 combined pharmacy-MBA programs across North America in 2015. We aimed to see if there would be support for a combined PharmD-MBA program at the University of Saskatchewan. (2) Methods: A questionnaire was distributed to 1st, 2nd, and 3rd year pharmacy students at the University of Saskatchewan. A separate questionnaire was developed and all practicing pharmacists in Saskatchewan were emailed a link to SurveyMonkey ® (Palo Alto, CA, USA) to fill it out online. In-person and phone interviews were conducted with pharmacy stakeholders in Saskatchewan and across the country. (3) Results: Of the 265 students, 193 (72.8%) were present on the days the questionnaires were distributed, and they all completed the questionnaires. When asked if they would have pursued a combined degree if the U of S had offered it when they entered the pharmacy program, 16.6% (32/193) and 37.3% (72/193) either strongly agreed or agreed and 29.0% (56/193) were unsure. When pharmacists were asked if an MBA would be valuable or applicable in their current job, 42.2% (128/303) agreed and 13.9% (42/303) strongly agreed. When asked if they felt students graduating with a combined degree would be at an advantage for certain job opportunities upon graduation, 33.6% (100/298) strongly agreed and 55.4% (165/298) agreed. A total of 8 interviews were conducted with key stakeholders from across Canada. Of these 8 stakeholders, only 2 were aware that other combined programs were offered. All of the stakeholders were in favour of the idea of a combined degree. Some felt it was important for the program to have a clear value proposition and healthcare related content would be desirable. (4) Conclusions: Overall, pharmacist, pharmacy student, and stakeholder input indicate that a combined program could be supported at the University of Saskatchewan.

  5. An Assessment of Demand for a Combined PharmD–MBA Program at the University of Saskatchewan

    Science.gov (United States)

    Mansell, Kerry; Bruneau-Bouchard, Antoine; Bruni-Bossio, Vincent

    2016-01-01

    (1) Background: Combined MBA programs are becoming increasingly popular, and it is anticipated that there will be 60 combined pharmacy–MBA programs across North America in 2015. We aimed to see if there would be support for a combined PharmD–MBA program at the University of Saskatchewan. (2) Methods: A questionnaire was distributed to 1st, 2nd, and 3rd year pharmacy students at the University of Saskatchewan. A separate questionnaire was developed and all practicing pharmacists in Saskatchewan were emailed a link to SurveyMonkey® (Palo Alto, CA, USA) to fill it out online. In-person and phone interviews were conducted with pharmacy stakeholders in Saskatchewan and across the country. (3) Results: Of the 265 students, 193 (72.8%) were present on the days the questionnaires were distributed, and they all completed the questionnaires. When asked if they would have pursued a combined degree if the U of S had offered it when they entered the pharmacy program, 16.6% (32/193) and 37.3% (72/193) either strongly agreed or agreed and 29.0% (56/193) were unsure. When pharmacists were asked if an MBA would be valuable or applicable in their current job, 42.2% (128/303) agreed and 13.9% (42/303) strongly agreed. When asked if they felt students graduating with a combined degree would be at an advantage for certain job opportunities upon graduation, 33.6% (100/298) strongly agreed and 55.4% (165/298) agreed. A total of 8 interviews were conducted with key stakeholders from across Canada. Of these 8 stakeholders, only 2 were aware that other combined programs were offered. All of the stakeholders were in favour of the idea of a combined degree. Some felt it was important for the program to have a clear value proposition and healthcare related content would be desirable. (4) Conclusions: Overall, pharmacist, pharmacy student, and stakeholder input indicate that a combined program could be supported at the University of Saskatchewan. PMID:28970393

  6. Strategic Communication and Social Media: An MBA Course from a Business Communication Perspective

    Science.gov (United States)

    Meredith, Michael J.

    2012-01-01

    Social media offers an exciting new area for our discipline to produce research and pedagogy that is in high demand by students, industry constituents, and other disciplines. This article discusses why business communication scholars should focus on social media as an important stream of study and outlines an MBA course in social media strategy…

  7. Introducing a Writing Coach into an MBA Course: Perspectives of Students and Coaches

    Science.gov (United States)

    Rice-Bailey, Tammy; Baker, Kimberly S.

    2017-01-01

    This article describes an interdisciplinary partnership that resulted in the introduction of a writing coach into an MBA class on critical and analytical thinking. By examining the response to this role by the writing coaches themselves and by the students enrolled in three sections of this new course, this exploratory study endeavors to answer…

  8. Student satisfaction and academic performance in a dual PharmD/MBA degree program.

    Science.gov (United States)

    Chumney, Elinor C G; Ragucci, Kelly R

    2006-04-15

    Evaluate the academic experience and satisfaction of students enrolled in the dual PharmD/MBA degree program between the South Carolina College of Pharmacy and The Citadel's School of Business Administration. Compare grade point averages of students enrolled in the dual degree program with those of traditional student colleagues. A standardized satisfaction survey instrument was administered to 32 students currently enrolled in the dual PharmD/MBA degree program. Grade point averages (GPAs) in both pharmacy and business coursework were also collected for analysis. There were slightly higher percentages of both female and minority students in the dual degree program compared to the pharmacy class as a whole. Eighteen (56%) of students completed the survey, and responses were generally positive. The mean GPA of students in the dual degree program was higher than that of both pharmacy (3.37 vs 3.08, p vs 3.64, not statistically significant) students not enrolled in the dual degree program. Students enrolled in the dual degree program did better academically than their counterparts and indicated an overall high level of satisfaction with the program.

  9. Synthesis and characterization of Au102(p-MBA)44 nanoparticles.

    Science.gov (United States)

    Levi-Kalisman, Yael; Jadzinsky, Pablo D; Kalisman, Nir; Tsunoyama, Hironori; Tsukuda, Tatsuya; Bushnell, David A; Kornberg, Roger D

    2011-03-09

    The synthesis of Au(102)(p-MBA)(44) nanoparticles on a preparative scale in high yield is described. Various analytical methods are shown to give results consistent with the composition and known structure of the particles, showing the preparation is essentially homogeneous, and attesting to the validity of the methods as well. Derivatization of the particles with proteins and DNA is demonstrated, and conditions are described for imaging individual particles by cryo-EM at low electron dose, close to focus, conditions optimal for recording high-resolution details.

  10. Concrescent Conversation as a Group Communication Tool in a Chinese University MBA Course

    Science.gov (United States)

    Akan, Obasi Haki; Andres, Hayward; Medley, Barbara C.

    2014-01-01

    In order to be more competitive in the global marketplace, China has adopted a long-term plan to reform their higher education system. One specific aim of this plan is to facilitate the achievement of China's goal of building a world-class market-driven economy through the development of an adequate supply of MBA-trained professional managers to…

  11. Why MBA Education...? An Examination of the Reasons for Pursuing a Management Course

    Science.gov (United States)

    Dhar, Rajib Lochan

    2011-01-01

    This study tries to examine the causes which have led to the rise in the number of students pursuing an MBA in India. Qualitative methods have been used to collect the data. Data were collected via six focused group discussions with 60 postgraduate students associated with different management institutes in western India. In addition, data were…

  12. Innovating in Health Care Management Education: Development of an Accelerated MBA and MPH Degree Program at Yale

    Science.gov (United States)

    Forman, Howard P.; Pistell, Anne F.; Nembhard, Ingrid M.

    2015-01-01

    Increasingly, there is recognition of the need for individuals with expertise in both management and public health to help health care organizations deliver high-quality and cost-effective care. The Yale School of Public Health and Yale School of Management began offering an accelerated Master of Business Administration (MBA) and Master of Public Health (MPH) joint degree program in the summer of 2014. This new program enables students to earn MBA and MPH degrees simultaneously from 2 fully accredited schools in 22 months. Students will graduate with the knowledge and skills needed to become innovative leaders of health care organizations. We discuss the rationale for the program, the developmental process, the curriculum, benefits of the program, and potential challenges. PMID:25706023

  13. 75 FR 47203 - Airworthiness Directives; McDonnell Douglas Corporation Model MD-11 and MD-11F Airplanes Equipped...

    Science.gov (United States)

    2010-08-05

    ... Airworthiness Directives; McDonnell Douglas Corporation Model MD- 11 and MD-11F Airplanes Equipped With General... Sec. 39.13 by adding the following new AD: 2010-16-03 McDonnell Douglas Corporation: Amendment 39... applies to McDonnell Douglas Corporation Model MD-11 and MD-11F airplanes, certified in any category...

  14. Conversion of a MBA to the treatment of biological wastes; Umnutzung einer MBA zur Bioabfallbehandlung

    Energy Technology Data Exchange (ETDEWEB)

    Deubig, Jan B. [Zentrale Abfallwirtschaft Kaiserslautern (ZAK) AoeR Kapiteltal, Kaiserslautern (Germany); Stadtmueller, Gregor [Zentrale Abfallwirtschaft Kaiserslautern (ZAK) AoeR Kapiteltal, Kaiserslautern (Germany). Abt. Technik; Greuel, Michael [Schirmer Umwelttechnik GmbH, Mainz (Germany); Deubig, Isabel [Zentrale Abfallwirtschaft Kaiserslautern (ZAK) AoeR Kapiteltal, Kaiserslautern (Germany). Abt. Stoffstrommanagement

    2013-03-01

    The Zentrale Abfallwirtschaft Kaiserslautern (ZAK) - gemeinsame kommunale Anstalt der Stadt und des Landkreises Kaiserslautern (Kaiserslautern, Federal Republic of Germany) is a public waste management authority being responsible for 250,000 inhabitants with respect to the utilization of municipal waste and with respect to the collection of problematic waste materials and electric appliances. Due to the changing framework conditions in the waste management, ZAK looks for solutions which facilitate the handling with increasing specific costs at simultaneously preservation of created values and compliance with social and ecologic standards. The change of the utilization of the cluster of plants to a mechanical-biological biowaste treatment plant within a regional cooperation project with formation of clusters in the waste management is an alternative to the unchanged continuation of the status quo or to a shutdown. Within the project transformation, existing power plants have been partly subject to a utilization conversion for the second time. ZAK increases its profile as a biomass competence centre. The MBA technology demonstrates its process-technical determined enhanced flexibility of mass flow.

  15. Md-miR156ab and Md-miR395 Target WRKY Transcription Factors to Influence Apple Resistance to Leaf Spot Disease.

    Science.gov (United States)

    Zhang, Qiulei; Li, Yang; Zhang, Yi; Wu, Chuanbao; Wang, Shengnan; Hao, Li; Wang, Shengyuan; Li, Tianzhong

    2017-01-01

    MicroRNAs (miRNAs) are key regulators of gene expression that post-transcriptionally regulate transcription factors involved in plant physiological activities. Little is known about the effects of miRNAs in disease resistance in apple ( Malus × domestica ). We globally profiled miRNAs in the apple cultivar Golden Delicious (GD) infected or not with the apple leaf spot fungus Alternaria alternaria f. sp. mali (ALT1), and identified 58 miRNAs that exhibited more than a 2-fold upregulation upon ALT1 infection. We identified a pair of miRNAs that target protein-coding genes involved in the defense response against fungal pathogens; Md-miR156ab targets a novel WRKY transcription factor, MdWRKYN1, which harbors a TIR and a WRKY domain. Md-miR395 targets another transcription factor, MdWRKY26, which contains two WRKY domains. Real-time PCR analysis showed that Md-miR156ab and Md-miR395 levels increased, while MdWRKYN1 and MdWRKY26 expression decreased in ALT1-inoculated GD leaves; furthermore, the overexpression of Md-miR156ab and Md-miR395 resulted in a significant reduction in MdWRKYN1 and MdWRKY26 expression. To investigate whether these miRNAs and their targets play a crucial role in plant defense, we overexpressed MdWRKYN1 or knocked down Md-miR156ab activity, which in both cases enhanced the disease resistance of the plants by upregulating the expression of the WRKY-regulated pathogenesis-related (PR) protein-encoding genes MdPR3-1, MdPR3-2, MdPR4, MdPR5, MdPR10-1 , and MdPR10-2 . In a similar analysis, we overexpressed MdWRKY26 or suppressed Md-miR395 activity, and found that many PR protein-encoding genes were also regulated by MdWRKY26 . In GD, ALT-induced Md-miR156ab and Md-miR395 suppress MdWRKYN1 and MdWRKY26 expression, thereby decreasing the expression of some PR genes, and resulting in susceptibility to ALT1.

  16. Constitutive equations for the Doi-Edwards model without independent alignment

    DEFF Research Database (Denmark)

    Hassager, Ole; Hansen, Rasmus

    2010-01-01

    We present two representations of the Doi-Edwards model without Independent Alignment explicitly expressed in terms of the Finger strain tensor, its inverse and its invariants. The two representations provide explicit expressions for the stress prior to and after Rouse relaxation of chain stretch......, respectively. The maximum deviations from the exact representations in simple shear, biaxial extension and uniaxial extension are of order 2%. Based on these two representations, we propose a framework for Doi-Edwards models including chain stretch in the memory integral form....

  17. Lessons from the Sea: A Case Study of an Experiential MBA International Management Course

    Science.gov (United States)

    Chaves, Wanda V.; Yacovelli, Steven R.

    2008-01-01

    This article describes the design and implementation of a unique course developed to deeply engage MBA students in the complexities of the field of international management. This experiential course was designed around an integrative project based on the cruise industry. The professor worked with the leadership team of a major cruise line to…

  18. 75 FR 80744 - Airworthiness Directives; McDonnell Douglas Corporation Model DC-9-81 (MD-81), DC-9-82 (MD-82...

    Science.gov (United States)

    2010-12-23

    ...-1203; Directorate Identifier 2010-NM-168-AD] RIN 2120-AA64 Airworthiness Directives; McDonnell Douglas... amends Sec. 39.13 by adding the following new airworthiness directive (AD): McDonnell Douglas Corporation... Douglas Corporation Model DC-9-81 (MD-81), DC-9-82 (MD-82), DC-9-83 (MD-83), DC-9-87 (MD-87) and MD-88...

  19. MBA sudents' satisfaction and loyality: state vs. private universities in Turkey

    Directory of Open Access Journals (Sweden)

    Nihat Kamil Anil

    2013-12-01

    Full Text Available The purpose of this paper is to explore the construct of student satisfaction and analyze its relationship with student loyalty in the context of state and private universities. A 45-item Turkish questionnaire adapted from literature, to which the authors added several items, was administered to MBA students of state- and private, foundation-owned universities located in Istanbul, as the largest city of Turkey. In this study, a two-step confirmative modeling strategy was chosen to test the hypotheses of the theoretical model by using LISREL 8. As the first step of the mentioned approach, a congruent and congeneric measurement model was established for each type of universities; then, in the second stage, hypotheses were tested by analyzing structural models. Research findings show a positive correlation between satisfaction and loyalty. The most important factors of satisfaction for the students attending state-owned universities are academic quality, teaching quality, and appropriateness of career opportunities; however, at private universities teaching quality and supportive services and appropriateness of career opportunities are the most significant factors. Administrative and the quality of library services turned out to be unimportant factors for MBA students both at state and private universities in this study. The distinguishing point of this study, which enhances its originality, was examining the difference between state and private universities separately.

  20. Simulation of groundwater flow in the Edwards-Trinity and related aquifers in the Pecos County region, Texas

    Science.gov (United States)

    Clark, Brian R.; Bumgarner, Johnathan R.; Houston, Natalie A.; Foster, Adam L.

    2014-01-01

    The Edwards-Trinity aquifer is a vital groundwater resource for agricultural, industrial, and public supply uses in the Pecos County region of western Texas. The U.S. Geological Survey completed a comprehensive, integrated analysis of available hydrogeologic data to develop a numerical groundwater-flow model of the Edwards-Trinity and related aquifers in the study area in parts of Brewster, Jeff Davis, Pecos, and Reeves Counties. The active model area covers about 3,400 square miles of the Pecos County region of Texas west of the Pecos River, and its boundaries were defined to include the saturated areas of the Edwards-Trinity aquifer. The model is a five-layer representation of the Pecos Valley, Edwards-Trinity, Dockum, and Rustler aquifers. The Pecos Valley aquifer is referred to as the alluvial layer, and the Edwards-Trinity aquifer is divided into layers representing the Edwards part of the Edwards-Trinity aquifer and the Trinity part of the Edwards-Trinity aquifer, respectively. The calibration period of the simulation extends from 1940 to 2010. Simulated hydraulic heads generally were in good agreement with observed values; 1,684 out of 2,860 (59 percent) of the simulated values were within 25 feet of the observed value. The average root mean square error value of hydraulic head for the Edwards-Trinity aquifer was 34.2 feet, which was approximately 4 percent of the average total observed change in groundwater-level altitude (groundwater level). Simulated spring flow representing Comanche Springs exhibits a pattern similar to observed spring flow. Independent geochemical modeling corroborates results of simulated groundwater flow that indicates groundwater in the Edwards-Trinity aquifer in the Leon-Belding and Fort Stockton areas is a mixture of recharge from the Barilla and Davis Mountains and groundwater that has upwelled from the Rustler aquifer.

  1. Does a plant for mechanical-biological waste treatment require a sanitary landfill?; Braucht die MBA eine Deponie?

    Energy Technology Data Exchange (ETDEWEB)

    Schulte, Burkart [GVoA mbH und Co. KG, Hille (Germany)

    2012-11-01

    In mechanical-biological waste treatment, an interesting recyclable fraction is dumped in landfill together with other treatment residues. This may be 10-20% depending on the energy content of the initial material. Some operators of mechanical-biological waste treatment plants are currently working on modifying their waste treatment processes. Results so far have shown that this may also reduce the cost. (orig.) [German] Bei der bisherigen Abfallentsorgung mittels einer MBA (mechanisch-biologische Abfallbehandlung) wird immer noch ein interessanter Wertstoffanteil mit dem Deponat auf der Deponie abgelagert. Je nach Qualitaet der Vorbehandlung sind dies alleine vom Energieinhalt des Eingangsmaterials ca. 10-20%. Um auch diesen Anteil zu verwerten, sind aktuell einige MBA-Betreiber dabei, ihre Verfahren entsprechend umzustellen. Erste Ergebnisse zeigen, dass dies auch noch zu Kosteneinsparungen fuehren kann. (orig.)

  2. How Are Task Reflexivity and Intercultural Sensitivity Related to the Academic Performance of MBA Students?

    Science.gov (United States)

    Lyubovnikova, Joanne; Napiersky, Uwe; Vlachopoulos, Panos

    2015-01-01

    Higher education in business school environments is increasingly focused on how to best equip students with the skills necessary for leadership in the global workplace. This paper examines the impact of two particularly important cognitive capabilities--task reflexivity and intercultural sensitivity, on academic performance in an MBA programme. It…

  3. mdFoam+: Advanced molecular dynamics in OpenFOAM

    Science.gov (United States)

    Longshaw, S. M.; Borg, M. K.; Ramisetti, S. B.; Zhang, J.; Lockerby, D. A.; Emerson, D. R.; Reese, J. M.

    2018-03-01

    This paper introduces mdFoam+, which is an MPI parallelised molecular dynamics (MD) solver implemented entirely within the OpenFOAM software framework. It is open-source and released under the same GNU General Public License (GPL) as OpenFOAM. The source code is released as a publicly open software repository that includes detailed documentation and tutorial cases. Since mdFoam+ is designed entirely within the OpenFOAM C++ object-oriented framework, it inherits a number of key features. The code is designed for extensibility and flexibility, so it is aimed first and foremost as an MD research tool, in which new models and test cases can be developed and tested rapidly. Implementing mdFoam+ in OpenFOAM also enables easier development of hybrid methods that couple MD with continuum-based solvers. Setting up MD cases follows the standard OpenFOAM format, as mdFoam+ also relies upon the OpenFOAM dictionary-based directory structure. This ensures that useful pre- and post-processing capabilities provided by OpenFOAM remain available even though the fully Lagrangian nature of an MD simulation is not typical of most OpenFOAM applications. Results show that mdFoam+ compares well to another well-known MD code (e.g. LAMMPS) in terms of benchmark problems, although it also has additional functionality that does not exist in other open-source MD codes.

  4. Additions and corrections to the lichen mycobiota of the subantarctic Prince Edward Islands

    NARCIS (Netherlands)

    Øvstedal, D.O.; Gremmen, N.J.M.

    2007-01-01

    Fifteen species are reported as new to the subantarctic Prince Edward Islands (47 degrees S, 38 degrees E). Of these 12 are added to the known lichens of Prince Edward Island, and four are added to the Marion Island species list. Two species are new to science, viz. Gyalecta azorellae Ovstedal, with

  5. Preparing MD-PhD students for clinical rotations: navigating the interface between PhD and MD training.

    Science.gov (United States)

    Goldberg, Charles; Insel, Paul A

    2013-06-01

    Many aspects of MD-PhD training are not optimally designed to prepare students for their future roles as translational clinician-scientists. The transition between PhD research efforts and clinical rotations is one hurdle that must be overcome. MD-PhD students have deficits in clinical skills compared with those of their MD-only colleagues at the time of this transition. Reimmersion programs (RPs) targeted to MD-PhD students have the potential to help them navigate this transition.The authors draw on their experience creating and implementing an RP that incorporates multiple types of activities (clinical exam review, objective structured clinical examination, and supervised practice in patient care settings) designed to enhance the participants' skills and readiness for clinical efforts. On the basis of this experience, they note that MD-PhD students' time away from the clinical environment negatively affects their clinical skills, causing them to feel underprepared for clinical rotations. The authors argue that participation in an RP can help students feel more comfortable speaking with and examining patients and decrease their anxiety regarding clinical encounters. The authors propose that RPs can have positive outcomes for improving the transition from PhD to clinical MD training in dual-degree programs. Identifying and addressing this and other transitions need to be considered to improve the educational experience of MD-PhD students.

  6. MARKET BASKET ANALYSIS (MBA PADA SITUS WEB E-COMMERCE ZAKIYAH COLLECTION

    Directory of Open Access Journals (Sweden)

    Ari Muzakir

    2016-11-01

    Full Text Available E-commerce menghubungkan antara produsen dengan produsen, produsen dengan konsumen, konsumen dengan produsen, konsumen dengan konsumen. Untuk mengimplementasi e-commerce dalam mendukung bisnis organisasi perlu di perhatikan 5 komponen utama yaitu ; pengembangan produk, promosi, transaksi online, product delivery dan after sales support. Hal ini yang tengah diterapkan pada Zakiyah Collection. Zakiyah Collection bergerak dibidang penjualan aneka macam kain khas Palembang seperti songket, blongket,tanjung, dan lain sebagainya. Untuk melakukan analisis terhadap pangsa pasar yang ada agar dapat bersaing dengan toko online lainnya dilakukan dengan strategi pemasaran dengan menggunakan pendekatan market basket analysis (MBA. MBA merupakan salah satu teknik dari data mining yang digunakan untuk menentukan produk-produk manakah yang akan dibeli oleh pelanggan secara bersamaan dengan melakukan analisa terhadap daftar transaksi pelanggan. Dengan mengetahui produk-produk tersebut, maka sebuah sistem e-commerce dapat membuat maupun mengembangkan sebuah sistem customer profiles dan dapat menentukan layout katalog pelanggannya sendiri. Model pengembangan sistem yang dilakukan menggunakan prototype dimana pelanggan dan pengguna akan dilibatkan secara langsung dalam proses ini. Hasil akhir dalam penelitian ini adalah berupa analisis data transaksi menggunakan market basket analysis dengan dilakukan 4 kali kombinasi produk yang berdasarkan nilai support x confidence terbesar dengan hasil berupa angka-angka kemungkinan transasksi yang berkaitan dengan produk yang dijual. Jika dengan menggunakan 1 kali kombinasi, maka didapatkan blongket dengan nilai support sebesar 0.5625. Jika dilakukan 2 kali kombinasi diperoleh kombinasi blongket dan songket dengan nilai support 0.375. Kata kunci: e-commerce, market basket analysis, association rules.

  7. The subantarctic Prince Edward Islands are globally important ...

    African Journals Online (AJOL)

    spamer

    (Vulnerable) has increased significantly, making Prince Edward Island equal with Marion Island as supporting ... 3 Marine & Coastal Management, Department of Environmental Affairs and Tourism, ... breeding on inaccessible cliff areas were estimated by ...... Penguin Conservation Assessment and Management Plan.

  8. An MBA Cohort's Use of an Enterprise Social Network for Collaborative Learning

    Science.gov (United States)

    Murphy, Glen D.

    2016-01-01

    The rapid pace of social media means that our understanding of the way in which it facilitates the learning process continues to lag. The findings of a longitudinal study of an executive MBA cohort over a period of eight months in their use of the social media application Yammer is presented. Student interaction data was analysed using a form of…

  9. The aquatic Coleoptera of Prince Edward Island, Canada: new records and faunal composition

    Directory of Open Access Journals (Sweden)

    Christopher Majka

    2008-09-01

    Full Text Available The aquatic Coleoptera (Gyrinidae, Haliplidae, Dytiscidae, Hydrophilidae, Elmidae, Dryopidae, Heteroceridae of Prince Edward Island, Canada is surveyed. Seventy-two species are now known to occur on Prince Edward Island, 26 of which are added to the island's faunal list. Three species, Gyrinus aquiris LeConte, Oulimnius latiusculus (LeConte, and Helichus striatus LeConte, are removed since there are no voucher specimens or published records to substantiate their presence. The name Dineutus horni is designated as an incorrect subsequent spelling of Dineutus hornii Roberts, 1895. The composition of the fauna is briefly discussed, both from regional and zoogeographic perspectives. There is only one introduced species, Helophorus grandis Illiger. Only one third of the aquatic fauna recorded on the neighbouring mainland has been found on Prince Edward Island, perhaps reflecting an island-associated diminution, the paucity of collecting, an area effect, or a combination of all these factors. The island faunas of Prince Edward Island, Cape Breton Island, and insular Newfoundland are compared. Prince Edward Island's is 36% smaller than the others, in contrast with the island's carabid fauna which is almost identical in magnitude with that of Cape Breton. This might reflect dispersal obstacles, the relative paucity of aquatic habitats on the island, or an insufficient collecting effort. Further research would be desirable, both to better discern the composition of the province's fauna, as well as to monitor the health of aquatic ecosystems in relation to anthropogenic activities.

  10. Estudo do impacto de um curso MBA em controladoria na evolução de seus egressos

    Directory of Open Access Journals (Sweden)

    Fábio Frezatti

    2003-10-01

    Full Text Available O ensino de pós-graduação tem evoluído de maneira muito acentuada a partir da premissa que traz conseqüências práticas em termos de benefícios aos participantes e às empresas. A grande busca tem se concentrado nos Master of Business Administration, criação norte-americana do início do século passado, que se expandiu para praticamente todas as partes do mundo. O estudo dos impactos dos cursos tem sido feito nos ambientes profissional e acadêmico. Abordando a evolução dos salários pré e pós MBA, o alcance de novos níveis na carreira e até mesmo a postura e aquisição de competências, os estudos buscam detectar os fatores que determinam o sucesso dos egressos dos cursos. A presente pesquisa examina a população de um programa brasileiro que foi implantado em 1994 e conta hoje com 17 turmas já formadas. Através de um questionário foram examinados o impacto do curso conforme percebido pelos egressos e sua evolução na carreira pós-MBA. Essas informações foram cruzadas com o perfil dos alunos e com seu desempenho acadêmico, buscando determinar os fatores que implicam no sucesso dos alunos após o curso. Para tanto, a pesquisa valeu-se da estatística descritiva e da Análise por Tabela de Contingência. Ao final, são apresentadas algumas conclusões iniciais e questões para aprofundamento.Post-graduate education has evolved in a very accentuated way on the basis of the premise that brings about practical consequences in terms of benefits to participants and companies. Demand has paramountly been concentrated in Master of Business Administration programs, a North-American creation from the beginning of the last century that has practically expanded all over the world.The impact of these courses has been studied in the professional and academic spheres. Dealing with salary evolution before and after the MBA, the achievement of new career levels and even the acquisition and attitude towards competencies, studies try to

  11. First thoughts on MD priorities for 2012

    CERN Document Server

    Zimmermann, F; Assmann, R

    2012-01-01

    In 2012, 22 days of beam time will be allocated for LHC MDs. In this paper, after recalling the 2011 LHC MD experience, the MD rrequests for 2012 are reviewed. Three primary MD themes for 2012 can be identified: 1)pushing performance in 2012, 2)preparing for 2014/15, and 3)towards maximum luminosity. Example topics include emittance growth in collision or enhanced satellites for theme 1), 25 ns operation for 2), and ATS optics for 3). Structures lists of MD requests and topics for each theme as well as some initial thoughts on the MD priorities are presented. For certain topics, "start-of-fill MDs" are proposed in order to most efficiently use of the available beam time.

  12. Online Academic Integrity: An Examination of MBA Students' Behavioral Intent of Engaging in Plagiarism

    Science.gov (United States)

    Bennett, Rashad A.

    2017-01-01

    With the proliferation of online graduate enrollment by 35.7% from 2003 to 2014, the literature indicates the number of reported academic integrity cases is on the rise. A quantitative correlational study was used to determine which determinants, if any, had a relationship to the behavioral intent to engage in plagiarism among MBA students…

  13. Synthesis, in vitro pharmacologic characterization, and preclinical evaluation of N-[2-(1'-piperidinyl)ethyl]-3-[125I]iodo-4-methoxybenzamide (P[125I]MBA) for imaging breast cancer

    International Nuclear Information System (INIS)

    John, Christy S.; Bowen, Wayne D.; Fisher, Susan J.; Lim, Benjamin B.; Geyer, Brian C.; Vilner, Bertold J.; Wahl, Richard L.

    1999-01-01

    The goal of this study was to investigate the potential use of a radioiodinated benzamide, N-[2-(1'-piperidinyl)ethyl]-3-iodo[ 125 I]-4-methoxybenzamide (P[ 125 I]MBA), a sigma receptor binding radioligand for imaging breast cancer. The chemical and radiochemical syntheses of PIMBA are described. The pharmacological evaluation of PIMBA was carried out for sigma-1 and sigma-2 receptor sites. The in vivo pharmacokinetics of the radioiodinated benzamide were determined in rats and comparison of P[ 125 I]MBA with Tc-99m sestamibi were made in a rat mammary tumor model. Sigma-1 affinity (K i ) for PIMBA in guinea pig brain membranes using [ 3 H](+)pentazocine was found to be 11.82±0.68 nM, whereas sigma-2 affinity in rat liver using [ 3 H]DTG (1,3-o-di-tolylguanidine) was 206±11 nM. Sites in guinea pig brain membranes labeled by P[ 125 I]MBA showed high affinity for haloperidol, (+)-pentazocine, BD1008, and PIMBA ( K i =4.87±1.49,8.81±1.97,0.057±0.005,46.9±1.8 nM, respectively). Competition binding studies were carried out in human ductal breast carcinoma cells (T47D). A dose-dependent inhibition of specific binding was observed with several sigma ligands. K i values for the inhibition of P[ 125 I]MBA binding in T47D cells for haloperidol, N-[2-(1'-piperidinyl)]ethyl]4-iodobenzamide (IPAB), N-(N-benzylpiperidin-4-yl)-4-iodobenzamide (4-IBP), and PIMBA were found to be 1.30±0.07, 13±1.5, 5.19±2.3, 1.06±0.5 nM, respectively. The in vitro binding data in guinea pig brain membranes and breast cancer cells confirmed binding to sigma sites. The saturation binding of P[ 125 I]MBA in T47D cells as studied by Scatchard analysis showed saturable binding, with a K d =94±7 nM and a B max =2035±305 fmol/mg of proteins. Biodistribution studies in Sprague-Dawley rats showed a rapid clearance of P[ 125 I]MBA from the normal organs. The potential of PIMBA in imaging breast cancer was evaluated in Lewis rats bearing syngeneic RMT breast cancers, a cancer that closely mimics

  14. Evaluating the Value-Added Impact of Outdoor Management Training for Leadership Development in an MBA Program

    Science.gov (United States)

    Kass, Darrin; Grandzol, Christian

    2012-01-01

    This study examined the benefits of Outdoor Management Training for the leadership development of students enrolled in an MBA-level Organizational Behavior course. Students enrolled in one of two experiential courses. Both were identical, except one included an intensive outdoor training component called Leadership on the Edge. The…

  15. Teaching MBA Students Teamwork and Team Leadership Skills: An Empirical Evaluation of a Classroom Educational Program

    Science.gov (United States)

    Hobson, Charles J.; Strupeck, David; Griffin, Andrea; Szostek, Jana; Rominger, Anna S.

    2014-01-01

    A comprehensive educational program for teaching behavioral teamwork and team leadership skills was rigorously evaluated with 148 MBA students enrolled at an urban regional campus of a Midwestern public university. Major program components included (1) videotaped student teams in leaderless group discussion (LGD) exercises at the course beginning…

  16. Cultural Values and Communication Online: Chinese and Southeast Asian Students in a Taiwan International MBA Class

    Science.gov (United States)

    Warden, Clyde A.; Chen, Judy F.; Caskey, D'Arcy

    2005-01-01

    Whereas many researchers have examined differences in values and behavior between Westerners and Asians, fewer have investigated differences within Asian cultural groups. A recent government initiative in Taiwan to encourage international education has led to the development of an international MBA program at the National Cheng Kung University in…

  17. The Coming Right-Brain Economy: Daniel H. Pink Says the MFA Is the New MBA

    Science.gov (United States)

    Connection: The Journal of the New England Board of Higher Education, 2005

    2005-01-01

    According to a recent "Harvard Business Review" piece by author Daniel H. Pink, MBA graduates are, in many ways, becoming this century's blue-collar workers--people who entered a workforce that was full of promise only to see their jobs move overseas. At the same time, businesses are realizing that the only way to differentiate their goods and…

  18. A comparative study for PSP toxins quantification by using MBA and HPLC official methods in shellfish.

    Science.gov (United States)

    Ben-Gigirey, B; Rodríguez-Velasco, M L; Otero, A; Vieites, J M; Cabado, A G

    2012-10-01

    Commission Regulation (EC) N° 2074/2005 recognises the biological method as the reference method for Paralytic Shellfish Poisoning (PSP) toxins detection in molluscs. It was amended by Commission Regulation (EC) N° 1664/2006 that accepted the so-called Lawrence method as an alternative to the reference method. The goal of this study was to compare AOAC Official Methods of Analysis 959.08 (Biological method) and 2005.06 (Prechromatographic Oxidation and Liquid Chromatography with fluorescence detection) in samples with different toxin profiles. The influence of extraction solvent in the total samples toxicity was also evaluated. A total of 40 samples including mussels, clams, scallops, razor-clams, cockles, oysters and barnacles were analysed by both official methods. Samples were selected with Alexandrium and Gymnodinium toxic profiles, from different origin and including several presentations: fresh, frozen, canned and boiled. Acetic and hydrochloric acid extractions were performed in all samples and the extracts were simultaneously analysed by both methods. Most samples were naturally contaminated and two samples were spiked. Comparison of both official methods, mouse bioassay (MBA) with HCl extraction and Liquid Chromatography with fluorescence detection (HPLC-FLD) with acetic acid extraction, led to an 85% of consistent results regarding compliance with legal limit, including samples below and above it. The linear correlation coefficient was r² = 0.69 and the paired t test (two tails, α = 0.05) indicated that there were not significant differences among both sets of data. Nevertheless, toxicity differences were found in several samples. In 15 out of 18 shellfish with a Gymnodinium toxic profile, higher toxicity levels were obtained by MBA. This fact was more evident in 7 samples, partially related to the lack of standards and the impossibility of analysing dc-NEO, C1, 2 and GTX6 at the beginning of the study. However, other factors concerning the extraction

  19. Explaining the Relationship between the Identification of Academics with Self-Leadership: A Study of MBA Graduates

    Science.gov (United States)

    Baxter, Matthew Jack

    2016-01-01

    How master of business administration (MBA) graduates influence themselves to achieve their objectives in their careers can be linked to how well they identified with academics throughout their education. It is important that scholars understand this relationship between academic and career performance. The ability to self-regulate, self-motivate,…

  20. Master of Business Administration (MBA) Student Outcomes in Vietnam: Graduate Student Insights from a Qualitative Study

    Science.gov (United States)

    Ly, Chau Thi Minh; Vickers, Margaret H.; Fernandez, Santha

    2015-01-01

    Purpose: Exploratory insights into the graduate student experiences of offshore MBA programmes in Vietnam are presented. Students are considered key stakeholders in the higher education (HE) debate, and their views were sought in light of recent shifts in HE worldwide, associated business education changes, nagging questions around the quality of…

  1. Spontaneous fission of 259Md

    International Nuclear Information System (INIS)

    Hulet, E.K.; Wild, J.F.; Lougheed, R.W.; Baisden, P.A.; Landrum, J.H.; Dougan, R.J.; Mustafa, M.; Ghiorso, A.; Nitschke, J.M.

    1979-01-01

    The mass and kinetic energy distributions of fission fragments from the spontaneous fission of th newly discovered nuclide 259 Md were obtained. 259 Md was identified as the E. C. daughter of 259 No, and was found to decay entirely (> 95%) by spontaneous fission with a 95-min half-life. From the kinetic energies measured for 397 pairs of coincident fragments, a mass distribution was derived that is symmetric with sigma = 13 amu. 259 Md, together with 258 Fm and 259 Fm, form a select group of three nuclides whose mass division in spontaneous fission is highly symmetric. Unlike the total-kinetic-energy (TKE) distributions of 258 Fm and 259 Fm, which peak at approx. = to 240 MeV, this distribution for 259 Md is broad and is 50 MeV lower in energy. Analysis of the mass and energy distributions shows that events near mass symmetry also exhibit a broad TKE distribution, with one-third of the symmetric events having TKEs less than 200 MeV. The associated of low TKEs with symmetric mass division in the fission of very heavy actinides is anomalous and inconsistent with theories based upon the emergence of fragment shells near the scission point. Either three-body fragmentation or peculiar fragment shapes are assumed as the cause for the large consumption of Coulomb energy observed for a significant fraction of symmetric fissions in 259 Md. 6 figures

  2. Edward Bond El teatro de compromiso social

    Directory of Open Access Journals (Sweden)

    Rosa López de D’Amico

    2015-10-01

    Full Text Available Este trabajo muestra un estudio de la obra del dramaturgo contemporáneo británico Edward Bond. El análisis está basado en la crítica literaria social a través del cual se estudia la violencia presente en la obra de Edward Bond. La investigación se presenta en secciones. En primera instancia, se propone una biografía del autor y la función que este le asigna al teatro. Seguidamente, se expone brevemente el desarrollo del teatro británico en el siglo XX. Luego se plantea un resumen de la obra objeto de estudio, Saved, y a continuación su correspondiente análisis, señalando las acciones violentas y su respectivo estudio. Además, se incluye un subcapítulo en donde se plantea la interrogante acerca de los aspectos positivos o negativos de la obra. En la última parte, se hace una breve revisión de otras obras escritas por el autor en donde se evidencia constantemente la violencia. En las conclusiones se exponen algunas ideas del autor, se plantea la validez del trabajo del escritor y se señala la importancia de este estudio en el proceso de enseñanza del inglés. AbstractThis paper presents a study of the works of the contemporary British playwright Edward Bond. The analysis is based on literary social criticism through which the violence present in the work of Edward Bond is studied. The research is presented in sections. In the first instance, there is a biography of the author and how this was refl ected in his work. Then the study describes briefl y the development of British theater in the twentieth century. Then the study presents a summary of the work under consideration and its corresponding analysis indicating the violent actions and their respective study. Also included is a subchapter where the question arises about the positive or negative aspects of the work. In the last part, there is a brief review of other works written by the author where violence is demonstrated consistently. The

  3. Cleveland's Multicultural Librarian: Eleanor (Edwards) Ledbetter, 1870-1954

    Science.gov (United States)

    Jones, Plummer Alston, Jr.

    2013-01-01

    Eleanor (Edwards) Ledbetter, who served immigrant populations in Cleveland throughout most of the Progressive Era and the Great Depression, was one of the first librarians to advocate for multiculturalism (then called cultural pluralism) as opposed to Americanism. In providing multicultural and multilingual library services for immigrants,…

  4. MdMYB9 and MdMYB11 are involved in the regulation of the JA-induced biosynthesis of anthocyanin and proanthocyanidin in apples.

    Science.gov (United States)

    An, Xiu-Hong; Tian, Yi; Chen, Ke-Qin; Liu, Xiao-Juan; Liu, Dan-Dan; Xie, Xing-Bin; Cheng, Cun-Gang; Cong, Pei-Hua; Hao, Yu-Jin

    2015-04-01

    Anthocyanin and proanthocyanidin (PA) are important secondary metabolites and beneficial to human health. Their biosynthesis is induced by jasmonate (JA) treatment and regulated by MYB transcription factors (TFs). However, which and how MYB TFs regulate this process is largely unknown in apple. In this study, MdMYB9 and MdMYB11 which were induced by methyl jasmonate (MeJA) were functionally characterized. Overexpression of MdMYB9 or MdMYB11 promoted not only anthocyanin but also PA accumulation in apple calluses, and the accumulation was further enhanced by MeJA. Subsequently, yeast two-hybrid, pull-down and bimolecular fluorescence complementation assays showed that both MYB proteins interact with MdbHLH3. Moreover, Jasmonate ZIM-domain (MdJAZ) proteins interact with MdbHLH3. Furthermore, chromatin immunoprecipitation-quantitative PCR and yeast one-hybrid assays demonstrated that both MdMYB9 and MdMYB11 bind to the promoters of ANS, ANR and LAR, whereas MdbHLH3 is recruited to the promoters of MdMYB9 and MdMYB11 and regulates their transcription. In addition, transient expression assays indicated that overexpression of MdJAZ2 inhibits the recruitment of MdbHLH3 to the promoters of MdMYB9 and MdMYB11. Our findings provide new insight into the mechanism of how MeJA regulates anthocyanin and PA accumulation in apple. © The Author 2014. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  5. COLLECTIVE EFFECTS AT INJECTION FOR THE APS-U MBA LATTICE

    Energy Technology Data Exchange (ETDEWEB)

    Lindberg, R.; Borland, M.; Blednykh, A.

    2017-06-25

    The Advanced Photon Source has proposed an upgrade to a multi-bend achromat (MBA) with a proposed timing mode calls for 48 bunches of 15 nC each. In this mode of operation we find that phase space mismatch from the booster can drive large wakefields that in turn may limit the current below that of the nominal collective instability threshold. We show that collective effects at injection lead to emittance growth that makes usual off-axis accumulation very challenging. On-axis injection ameliorates many of these issues, but we find that transverse feedback is still required. We explore the role of impedance, feedback, and phase-space mismatch on transverse instabilities at injection.

  6. Muscular Dystrophy (MD)

    Science.gov (United States)

    ... patients may need assisted ventilation to treat respiratory muscle weakness and a pacemaker for cardiac abnormalities. View Full Treatment Information Definition The muscular dystrophies (MD) are a group of more than 30 ...

  7. Enzyme-free colorimetric determination of EV71 virus using a 3D-MnO2-PEG nanoflower and 4-MBA-MA-AgNPs.

    Science.gov (United States)

    Chu, Chengchao; Ge, Shengxiang; Zhang, Jing; Lin, Huirong; Liu, Gang; Chen, Xiaoyuan

    2016-09-15

    We present a simple colorimetric assay for EV71 virus detection based on the aggregation of 4-mercaptobenzoic acid (4-MBA) and melamine (MA) modified silver nanoparticles (4-MBA-MA-AgNPs) in the presence of Mn 2+ . The EV71-Ab 1 was incubated on a 96-well plate and the EV71-Ab 2 was labeled on the surface of three-dimensional nanoflower-like MnO 2 -PEG (3D-MnO 2 -PEG). After layer-by-layer immunoreactions, the EV71 virus and the corresponding 3D-MnO 2 -PEG-Ab 2 were captured on the plate. With the addition of Vitamin C (Vc), Mn 2+ was released from the 3D-MnO 2 -PEG and then the aggregation of the 4-MBA-MA-AgNPs was induced, allowing a naked-eye detection limit of EV71 virus to be as low as 5 × 10 4 particles per mL, which is about three orders of magnitude lower than the conventional enzyme-linked immunosorbent assay (ELISA). This enzyme-free immunoassay based on a hybrid 3D-MnO 2 features signal amplification strategies via a simple reduction reaction.

  8. ProtoMD: A prototyping toolkit for multiscale molecular dynamics

    Science.gov (United States)

    Somogyi, Endre; Mansour, Andrew Abi; Ortoleva, Peter J.

    2016-05-01

    ProtoMD is a toolkit that facilitates the development of algorithms for multiscale molecular dynamics (MD) simulations. It is designed for multiscale methods which capture the dynamic transfer of information across multiple spatial scales, such as the atomic to the mesoscopic scale, via coevolving microscopic and coarse-grained (CG) variables. ProtoMD can be also be used to calibrate parameters needed in traditional CG-MD methods. The toolkit integrates 'GROMACS wrapper' to initiate MD simulations, and 'MDAnalysis' to analyze and manipulate trajectory files. It facilitates experimentation with a spectrum of coarse-grained variables, prototyping rare events (such as chemical reactions), or simulating nanocharacterization experiments such as terahertz spectroscopy, AFM, nanopore, and time-of-flight mass spectroscopy. ProtoMD is written in python and is freely available under the GNU General Public License from github.com/CTCNano/proto_md.

  9. Synthesis, in vitro pharmacologic characterization, and preclinical evaluation of N-[2-(1'-piperidinyl)ethyl]-3-[{sup 125}I]iodo-4-methoxybenzamide (P[{sup 125}I]MBA) for imaging breast cancer

    Energy Technology Data Exchange (ETDEWEB)

    John, Christy S. E-mail: radcsj@gwumc.edu; Bowen, Wayne D.; Fisher, Susan J.; Lim, Benjamin B.; Geyer, Brian C.; Vilner, Bertold J.; Wahl, Richard L

    1999-05-01

    The goal of this study was to investigate the potential use of a radioiodinated benzamide, N-[2-(1'-piperidinyl)ethyl]-3-iodo[{sup 125}I]-4-methoxybenzamide (P[{sup 125}I]MBA), a sigma receptor binding radioligand for imaging breast cancer. The chemical and radiochemical syntheses of PIMBA are described. The pharmacological evaluation of PIMBA was carried out for sigma-1 and sigma-2 receptor sites. The in vivo pharmacokinetics of the radioiodinated benzamide were determined in rats and comparison of P[{sup 125}I]MBA with Tc-99m sestamibi were made in a rat mammary tumor model. Sigma-1 affinity (K{sub i}) for PIMBA in guinea pig brain membranes using [{sup 3}H](+)pentazocine was found to be 11.82{+-}0.68 nM, whereas sigma-2 affinity in rat liver using [{sup 3}H]DTG (1,3-o-di-tolylguanidine) was 206{+-}11 nM. Sites in guinea pig brain membranes labeled by P[{sup 125}I]MBA showed high affinity for haloperidol, (+)-pentazocine, BD1008, and PIMBA (K{sub i}=4.87{+-}1.49,8.81{+-}1.97,0.057{+-}0.005,46.9{+-}1.8 nM), respectively). Competition binding studies were carried out in human ductal breast carcinoma cells (T47D). A dose-dependent inhibition of specific binding was observed with several sigma ligands. K{sub i} values for the inhibition of P[{sup 125}I]MBA binding in T47D cells for haloperidol, N-[2-(1'-piperidinyl)]ethyl]4-iodobenzamide (IPAB), N-(N-benzylpiperidin-4-yl)-4-iodobenzamide (4-IBP), and PIMBA were found to be 1.30{+-}0.07, 13{+-}1.5, 5.19{+-}2.3, 1.06{+-}0.5 nM, respectively. The in vitro binding data in guinea pig brain membranes and breast cancer cells confirmed binding to sigma sites. The saturation binding of P[{sup 125}I]MBA in T47D cells as studied by Scatchard analysis showed saturable binding, with a K{sub d}=94{+-}7 nM and a B{sub max}=2035{+-}305 fmol/mg of proteins. Biodistribution studies in Sprague-Dawley rats showed a rapid clearance of P[{sup 125}I]MBA from the normal organs. The potential of PIMBA in imaging breast cancer was

  10. Food for thought: New international MBA focusing on the food sector at Aarhus School of Business in Denmark

    DEFF Research Database (Denmark)

    Stacey, Julia

    2003-01-01

    The Aarhus School of Business in Denmark now launches a new international MBA Programme focussing on the food sector. The programme is designed to provide managers in the food sector with knowledge and managerial skills enabling them to rise to challenges that will face tomorrow's food sector....

  11. Harvesting graphics power for MD simulations

    NARCIS (Netherlands)

    van Meel, J.A.; Arnold, A.; Frenkel, D.; Portegies Zwart, S.F.; Belleman, R.G.

    2008-01-01

    We discuss an implementation of molecular dynamics (MD) simulations on a graphic processing unit (GPU) in the NVIDIA CUDA language. We tested our code on a modern GPU, the NVIDIA GeForce 8800 GTX. Results for two MD algorithms suitable for short-ranged and long-ranged interactions, and a

  12. Harvesting graphics power for MD simulations

    NARCIS (Netherlands)

    Meel, J.A. van; Arnold, A.; Frenkel, D.; Portegies Zwart, S.F.; Belleman, R.G.

    We discuss an implementation of molecular dynamics (MD) simulations on a graphic processing unit (GPU) in the NVIDIA CUDA language. We tested our code on a modern GPU, the NVIDIA GeForce 8800 GTX. Results for two MD algorithms suitable for short-ranged and long-ranged interactions, and a

  13. Understanding the MBA Gender Gap: Women Respond to Gender Norms by Reducing Public Assertiveness but Not Private Effort.

    Science.gov (United States)

    Wallen, Aaron S; Morris, Michael W; Devine, Beth A; Lu, Jackson G

    2017-08-01

    Women's underperformance in MBA programs has been the subject of recent debate and policy interventions, despite a lack of rigorous evidence documenting when and why it occurs. The current studies document a performance gap, specifying its contours and contributing factors. Two behaviors by female students that may factor into the gap are public conformity and private internalization. We predicted that women conform to the norm associating maleness with technical prowess by minimizing their public assertiveness in class discussions and meetings, but that they do not internalize the norm by reducing private effort. Data from multiple cohorts of a top-ranked MBA program reveal female underperformance occurred in technical subjects (e.g., accounting), but not social subjects (e.g., marketing). As predicted, the gender effect ran not through private effort but through public assertiveness, even controlling for gender differences in interests and aptitudes. These findings support some current policy interventions while casting doubt on others.

  14. Introducing Edward L. Bernays, the "Father of Public Relations."

    Science.gov (United States)

    Yeager, Robert J.

    1985-01-01

    Relates some of the public relations achievements and techniques of Edward L. Bernays. Sees modern public relations proceeding from an understanding of individuals, institutions and social groups, and their interrelationships. Considers the information dissemination, persuasion, and attitude integration functions of public relations. Lists…

  15. A new species of Trichopeltarion A. Milne-Edwards, 1880, from the Southwestern Atlantic (Crustacea: Brachyura: Atelecyclidae

    Directory of Open Access Journals (Sweden)

    Marcos Tavares

    2005-01-01

    Full Text Available A new species of Trichopeltarion A. Milne-Edwards, 1880, is described from off coast of Brazil, namely Trichopeltarion pezzutoi n. sp. The new species is compared to its Atlantic congeners, Trichopeltarion nobile A. Milne-Edwards, 1880, and Trichopeltarion intesi (Crosnier, 1981. The record of T. nobile from Brazil should actually be attributed to T. pezzutoi n. sp. The differences between the genera Trichopeltarion and Peltarion Jacquinot, 1847 are discussed.Uma nova espécie do gênero Trichopeltarion A. Milne-Edwards, 1880 coligida no talude continental brasileiro é descrita e ilustrada, nomeadamente Trichopeltarion pezzutoi n. sp. A nova espécie é comparada às suas congêneres do oceano Atlântico, Trichopeltarion nobile A. Milne-Edwards, 1880 e Trichopeltarion intesi (Crosnier, 1981. O registro de T. nobile para o Brasil deve ser atribuído à T. pezzutoi n. sp. São discutidas as diferenças entre os gêneros Trichopeltarion e Peltarion Jacquinot, 1847.

  16. Edward Christopher Williams and His Impact on Librarianship.

    Science.gov (United States)

    Latimer, Carlos

    Edward Christopher Williams had a major impact on librarianship, not only as the first documented African American to graduate from a library school, but also as a developer of education for librarians and as an active member of the American Library Association (ALA) and the Ohio Library Association. This study used the historical methodology…

  17. Combining Rosetta with molecular dynamics (MD): A benchmark of the MD-based ensemble protein design.

    Science.gov (United States)

    Ludwiczak, Jan; Jarmula, Adam; Dunin-Horkawicz, Stanislaw

    2018-07-01

    Computational protein design is a set of procedures for computing amino acid sequences that will fold into a specified structure. Rosetta Design, a commonly used software for protein design, allows for the effective identification of sequences compatible with a given backbone structure, while molecular dynamics (MD) simulations can thoroughly sample near-native conformations. We benchmarked a procedure in which Rosetta design is started on MD-derived structural ensembles and showed that such a combined approach generates 20-30% more diverse sequences than currently available methods with only a slight increase in computation time. Importantly, the increase in diversity is achieved without a loss in the quality of the designed sequences assessed by their resemblance to natural sequences. We demonstrate that the MD-based procedure is also applicable to de novo design tasks started from backbone structures without any sequence information. In addition, we implemented a protocol that can be used to assess the stability of designed models and to select the best candidates for experimental validation. In sum our results demonstrate that the MD ensemble-based flexible backbone design can be a viable method for protein design, especially for tasks that require a large pool of diverse sequences. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Feyz Kashani and Jonathan Edwards on the Place of Heart in Religious Knowledge

    Directory of Open Access Journals (Sweden)

    Saham Asadinia

    2014-08-01

    Full Text Available This essay seeks to summarize and compare the theological ideas of Jonathan Edwards, a western philosopher, with those of Feyz Kashani, an eastern philosopher. The reason for this study is the numerous conjunctions that are seen in their ideas. These include the harmony of heart and reason in respect to belief, the priority of the heart in the reflection of truth, the belief in centrality of the religion of heart, the necessity of divine grace in the flow of religious knowledge, the emphasis on the esoteric side of religion as opposed to the exoteric side, and the importance of a practical approach to religion. Significant differences also exist between their ideas. For instance, Edwards believes that human nature is sinful and corrupted while Feyz does not believe this is true. Furthermore, Feyz interprets the path of heart to be based on reason, while Edwards has a different point of view.

  19. Social Perspective and Educational Knowledge: Edward L. Thorndike Reexamined.

    Science.gov (United States)

    Franklin, Barry M.

    This paper examines the relationship between educational theorist Edward L. Thorndike's psychology and his social viewpoint. Many of the revisionists in educational history have oversimplified Thorndike's thought by not examining his views from this perspective. Thorndike's educational ideas and practices are reflections of certain fundamental…

  20. Tumor microvascular changes in antiangiogenic treatment : Assessment by magnetic resonance contrast media of different molecular weights

    NARCIS (Netherlands)

    Turetschek, K; Preda, A; Novikov, [No Value; Brasch, RC; Weinmann, HJ; Wunderbaldinger, P; Roberts, TPL

    Purpose: To test magnetic resonance (MR) contrast media of different molecular weights (MWs) for their potential to characterize noninvasively microvascular changes in an experimental tumor treatment model. Materials and Methods: MD-MBA-435, a poorly differentiated human breast cancer cell line, was

  1. MD2190: Q" Stabilization during injection

    CERN Document Server

    Schenk, Michael; Li, Kevin Shing Bruce; Malina, Lukas; Metral, Elias; Tomas Garcia, Rogelio; CERN. Geneva. ATS Department

    2018-01-01

    This MD is a follow-up study of MD1831, where single bunches were stabilized against impedance-driven instabilities at 6.5 TeV in the LHC with Q''. The goals are (i) to explore whether an amplitude detuning free Q'' knob can be implemented at injection energy, and (ii) whether Q'' can provide beam stability at injection, where the beams suffer mostly from electron cloud effects. Ideally, this would relax the use of the Landau octupoles and may help in preserving the beam quality by reducing dynamic aperture limitations originating from the octupoles. The MD has been split into two parts: First, optics corrections were put in place to minimize beta-beating and linear coupling introduced by the knobs. The corrections were achieved by means of orbit bumps and skew quadrupole knobs. Machine safety was then validated with loss maps. While the betatron loss maps were approved, the off-momentum maps showed a priori unexpected losses in several arcs and the MD was stopped at this point for reasons of machine protecti...

  2. Freies Geleit für Edward Snowden? / Matthias Friehe, Christopher Lipp

    Index Scriptorium Estoniae

    Friehe, Matthias

    2014-01-01

    Parlamendi uurimiskomisjoni ette kutsutavate tunnistajate julgeoleku tagamisest Edward Snowdeni juhtumi põhjal; kurjategija väljaandmiskohustusest ja tema karistuse käsitlusest Saksa karistusseadustiku järgi

  3. Optimization of Edwards vacuum coating unit model E12E for the production of thin films.; Optimizacion de la evaporadora Edwards modelo E12E para la fabricacion de peliculas delgadas.

    Energy Technology Data Exchange (ETDEWEB)

    Ruiz P, H S

    1995-10-01

    This work is about an Edwards vacuum coating unit model E12E, it shows the principle of vacuum thermal evaporation, some observations in the operation of vacuum diffusion pumps, mechanical pumps, vacuum gauge, Penning and Pirani, and some equations of leak vacuum, after the modifications and additions of Edwards vacuum coating unit for optimization, the last part contains a concise introduction about thin films and one specific application, it also contains the recommendations and requirements to keep the system in good conditions. (Author).

  4. Struggles for Educational Equity in Prince Edward County, VA: Resistance, Southern Manifesto Ideologies, and School Choice

    Science.gov (United States)

    Tillerson-Brown, Amy

    2016-01-01

    In light of contemporary school choice proposals and the 60th anniversary of the Southern Manifesto, the Prince Edward County, Virginia public schools crisis provides interesting historical discussion. Prince Edward County (PEC), a rural community in central Virginia, was one of five school districts represented in the 1954 "Brown v. Board of…

  5. Edward Teller Biographical Memoir

    Energy Technology Data Exchange (ETDEWEB)

    Libby, S B; Sessler, A M

    2009-07-27

    Edward Teller died on September 9, 2003 in Stanford, California at the age of 95. He was both one of the great theoretical physicists of the twentieth century and a leading figure in the development of nuclear weapons and broader defense advocacy. Teller's work in physics, spanning many decades of the twentieth century, includes some of the most fundamental insights in the quantum behaviors of molecules and their spectra, nuclei, surfaces, solid state and spin systems, and plasmas. In the defense arena, Teller is best known for his key insight that made thermonuclear weapons possible. Teller was both a great scientific collaborator and physics teacher at all levels, known for his openness, generosity, personal warmth, and powerful physical intuition. Many of his graduate students went on to illustrious careers.

  6. Geologic framework and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Texas

    Science.gov (United States)

    Clark, Allan K.; Golab, James A.; Morris, Robert R.

    2016-11-28

    During 2014–16, the U.S. Geological Survey, in cooperation with the Edwards Aquifer Authority, documented the geologic framework and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Texas. The Edwards and Trinity aquifers are major sources of water for agriculture, industry, and urban and rural communities in south-central Texas. Both the Edwards and Trinity are classified as major aquifers by the State of Texas.The purpose of this report is to present the geologic framework and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Tex. The report includes a detailed 1:24,000-scale hydrostratigraphic map, names, and descriptions of the geology and hydrostratigraphic units (HSUs) in the study area.The scope of the report is focused on geologic framework and hydrostratigraphy of the outcrops and hydrostratigraphy of the Edwards and Trinity aquifers within northern Bexar and Comal Counties, Tex. In addition, parts of the adjacent upper confining unit to the Edwards aquifer are included.The study area, approximately 866 square miles, is within the outcrops of the Edwards and Trinity aquifers and overlying confining units (Washita, Eagle Ford, Austin, and Taylor Groups) in northern Bexar and Comal Counties, Tex. The rocks within the study area are sedimentary and range in age from Early to Late Cretaceous. The Miocene-age Balcones fault zone is the primary structural feature within the study area. The fault zone is an extensional system of faults that generally trends southwest to northeast in south-central Texas. The faults have normal throw, are en echelon, and are mostly downthrown to the southeast.The Early Cretaceous Edwards Group rocks were deposited in an open marine to supratidal flats environment during two marine transgressions. The Edwards Group is composed of the Kainer and Person Formations. Following tectonic uplift, subaerial exposure, and erosion near the end of

  7. conserving surface-nesting seabirds at the prince edward islands

    African Journals Online (AJOL)

    South Africa's subantarctic Prince Edward Islands support substantial proportions of the global populations of a number of surface-nesting seabirds. Populations of most of these have decreased at the islands since the 1980s and 12 of 16 species are regarded as Threatened or Near Threatened regionally or internationally.

  8. The small ubiquitin-like modifier E3 ligase MdSIZ1 promotes anthocyanin accumulation by sumoylating MdMYB1 under low-temperature conditions in apple.

    Science.gov (United States)

    Zhou, Li-Jie; Li, Yuan-Yuan; Zhang, Rui-Fen; Zhang, Chun-Ling; Xie, Xing-Bin; Zhao, Cheng; Hao, Yu-Jin

    2017-10-01

    MdMYB1 acts as a crucial component of the MYB-bHLH-WD40 complex to regulate anthocyanin biosynthesis in red-skinned apples (Malus domestica), but little is known about its post-translational regulation. Here, a small ubiquitin-like modifier E3 ligase MdSIZ1 was screened out as an MdMYB1-interacting protein with a yeast two-hybridization approach. The interaction between MdSIZ1 and MdMYB1 was further verified with pull-down and CoIP assays. Furthermore, it was found that MdSIZ1 directly sumoylated MdMYB1 proteins in vivo and in vitro, especially under moderately low temperature (17 °C) conditions, and that this sumoylation was required for MdMYB1 protein stability. Moreover, the transcription level of MdSIZ1 gene was remarkably induced by low temperature and phosphorus deficiency, and MdSIZ1 overexpression exerted a large positive influence on anthocyanin accumulation and red fruit coloration, suggesting its important role in the regulation of anthocyanin biosynthesis under stress conditions. Our findings reveal an important role for a small ubiquitin-like modifier modification of MYB transcription factors in regulation of anthocyanin biosynthesis in plants. © 2017 John Wiley & Sons Ltd.

  9. MdCOP1 Ubiquitin E3 Ligases Interact with MdMYB1 to Regulate Light-Induced Anthocyanin Biosynthesis and Red Fruit Coloration in Apple1[W][OA

    Science.gov (United States)

    Li, Yuan-Yuan; Mao, Ke; Zhao, Cheng; Zhao, Xian-Yan; Zhang, Hua-Lei; Shu, Huai-Rui; Hao, Yu-Jin

    2012-01-01

    MdMYB1 is a crucial regulator of light-induced anthocyanin biosynthesis and fruit coloration in apple (Malus domestica). In this study, it was found that MdMYB1 protein accumulated in the light but degraded via a ubiquitin-dependent pathway in the dark. Subsequently, the MdCOP1-1 and MdCOP1-2 genes were isolated from apple fruit peel and were functionally characterized in the Arabidopsis (Arabidopsis thaliana) cop1-4 mutant. Yeast (Saccharomyces cerevisiae) two-hybrid, bimolecular fluorescence complementation, and coimmunoprecipitation assays showed that MdMYB1 interacts with the MdCOP1 proteins. Furthermore, in vitro and in vivo experiments indicated that MdCOP1s are necessary for the ubiquitination and degradation of MdMYB1 protein in the dark and are therefore involved in the light-controlled stability of the MdMYB1 protein. Finally, a viral vector-based transformation approach demonstrated that MdCOP1s negatively regulate the peel coloration of apple fruits by modulating the degradation of the MdMYB1 protein. Our findings provide new insight into the mechanism by which light controls anthocyanin accumulation and red fruit coloration in apple and even other plant species. PMID:22855936

  10. Environmental Assessment of Lead at Camp Edwards, Massachusetts, Small Arms Ranges

    National Research Council Canada - National Science Library

    Clausen, Jay L; Korte, Nic; Bostick, Benjamin; Rice, Benjamin; Walsh, Matthew; Nelson, Andrew

    2007-01-01

    Environmental issues for small arms training with lead projectiles are examined in this report for Camp Edwards, Massachusetts, in order to evaluate whether past or future use of lead in small arms...

  11. President Edwards and the Sage of Highgate: Determinism, Depravity, and the Supernatural Will.

    Science.gov (United States)

    Bannon, Brad

    2016-01-01

    Scarce attention has been given to Samuel Taylor Coleridge's engagement with the philosophical theology of Jonathan Edwards, and yet a clear understanding of each thinker's position on determinism and Original Sin is of vital importance if we are understand the lasting significance of their disagreements. There have been a number of studies to take up Coleridge's influence on the American Romantics, but there is no scholarship that has taken into account how the reception of this influence was inflected both by the legacy of Edwards and by the critical response that his theology elicited from Coleridge.

  12. Granular statistical mechanics - Building on the legacy of Sir Sam Edwards

    Science.gov (United States)

    Blumenfeld, Raphael

    When Sir Sam Edwards laid down the foundations for the statistical mechanics of jammed granular materials he opened a new field in soft condensed matter and many followed. In this presentation we review briefly the Edwards formalism and some of its less discussed consequences. We point out that the formalism is useful for other classes of systems - cellular and porous materials. A certain shortcoming of the original formalism is then discussed and a modification to overcome it is proposed. Finally, a derivation of an equation of state with the new formalism is presented; the equation of state is analogous to the PVT relation for thermal gases, relating the volume, the boundary stress and measures of the structural and stress fluctuations. NUDT, Changsha, China, Imperial College London, UK, Cambridge University, UK.

  13. Norforce: Major General Edward Northey and the Nyasaland and ...

    African Journals Online (AJOL)

    The campaign in East and Central Africa during the First World War has received relatively little attention despite the remarkable exploits of Major General Edward Northey and Norforce. In field command for two and a half years, he successfully led a multi-ethnic and polyglot force across some of the most difficult terrain of ...

  14. Edward Jenner and the small pox vaccine

    OpenAIRE

    Kendall A Smith

    2011-01-01

    Edward Jenner, who discovered that it is possible to vaccinate against Small Pox using material from Cow Pox, is rightly the man who started the science of immunology. However, over the passage of time many of the details surrounding his astounding discovery have been lost or forgotten. Also, the environment within which Jenner worked as a physician in the countryside, and the state of the art of medicine and society are difficult to appreciate today. It is important to recall that people wer...

  15. Edward C. Little Water Recycling Plant, El Segundo, CA: CA0063401

    Science.gov (United States)

    Joint EPA and Los Angeles Regional Water Quality Control Board NPDES Permit and Waiver from Secondary Treatment for the West Basin Municipal Water District Edward C. Little Water Recycling Plant, El Segundo, CA: CA0063401

  16. Prison Field Trips: Can White-Collar Criminals Positively Affect the Ethical and Legal Behavior of Marketing and MBA Students?

    Science.gov (United States)

    Castleberry, Stephen B.

    2007-01-01

    Marketing educators bear some responsibility for teaching ethics and legal issues to their students. Visits to white-collar criminals in a federal prison camp are one method of achieving this task. This article develops and empirically assesses ten objectives for such a visit by MBA and undergraduate marketing classes. Undergraduates rated the…

  17. Long-term results of heart valve replacement with the Edwards Duromedics bileaflet prosthesis: a prospective ten-year clinical follow-up.

    Science.gov (United States)

    Podesser, B K; Khuenl-Brady, G; Eigenbauer, E; Roedler, S; Schmiedberger, A; Wolner, E; Moritz, A

    1998-05-01

    The Edwards Duromedics valve (Baxter Healthcare Corp., Edwards Division, Santa Ana, Calif.) was designed with a self-irrigating hinge mechanism to reduce thromboembolic complications. After good initial clinical results, distribution was suspended in 1988 after reports of valve fracture after 20,000 valves had been implanted. The manufacturer conducted extensive studies to improve the Edwards Duromedics and reintroduced a modified version, which is available as Edwards Tekna. The purpose of the study was the evaluation of long-term results of the original Edwards Duromedics that might be important for the current version, the Edwards Tekna valve. A prospective clinical 10-year follow-up was performed of 508 patients who underwent valve replacement with the Edwards Duromedics valve in the aortic (n = 268), mitral (n = 183), and aortic and mitral (n = 56) position. The perioperative mortality rate was 6.9%; follow-up was 98% complete, comprising 3648 patient-years for a mean follow-up of 86 months (range: 33 to 144 months). The actuarial freedom from complications at the 10-year follow-up and the incidence rate (percent per patient-year) were as follows: late mortality rate, 69.2% +/- 2.4% (3.5% per patient-year); thromboembolism, 90.7% +/- 1.6% (0.96% per patient-year); anticoagulation-related hemorrhage, 87.7% +/- 1.7% (1.34% per patient-year); prosthetic valve endocarditis, 96.7% +/- 0.09% (0.38% per patient-year); valve-related mortality rate, 89.3% +/- 1.6% (1.21% per patient-year); valve failure, 86.2% +/- 1.85% (1.54% per patient-year); and valve-related morbidity and mortality rate, 71.1% +/- 2.3% (3.2% per patient-year). Three leaflet escapes were observed (one lethal, two successful reoperations; 99.1% +/- 0.05% freedom, 0.08% per patient-year). All patients functionally improved (86% in New York Heart Association classes I and II), and incidence of anemia was insignificant. These results confirm that the Edwards Duromedics valve shows excellent performance

  18. Bibliography of the Edwards Aquifer, Texas, through 1993

    Science.gov (United States)

    Menard, J.A.

    1995-01-01

    The bibliography comprises 1,022 multidisciplinary references to technical and general literature for the three regions of the Edwards aquifer, Texas-San Antonio area; Barton Springs segment, Austin area; and northern segment, Austin area. The references in the bibliography were compiled from computerized data bases and from published bibliographies and reports. Dates of references range from the late 1800's through 1993. Subject and author indexes are included.

  19. Reception of Edward Bernays' Doctrine of "Manipulating Public Opinion."

    Science.gov (United States)

    Olasky, Marvin N.

    Ivy Lee and Edward Bernays are generally regarded as the founding fathers of modern public relations. While Lee has been the subject of a full biography that included contemporary reaction to his ideas, there has been no similar work on how Bernays' ideas were received, though his ideas were in some ways more radical. He believed that propaganda…

  20. The AINTEGUMENTA genes, MdANT1 and MdANT2, are associated with the regulation of cell production during fruit growth in apple (Malus × domestica Borkh.).

    Science.gov (United States)

    Dash, Madhumita; Malladi, Anish

    2012-06-25

    Fruit growth in apple (Malus × domestica Borkh.) is mediated by cell production and expansion. Genes involved in regulating these processes and thereby fruit growth, are not well characterized. We hypothesized that the apple homolog(s) of AINTEGUMENTA (ANT), an APETALA2-repeat containing transcription factor, regulates cell production during fruit growth in apple. Two ANT genes, MdANT1 and MdANT2, were isolated from apple and their expression was studied during multiple stages of fruit development. MdANT1 and MdANT2 expression was high during early fruit growth coincident with the period of cell production, rapidly declined during exit from cell production, and remained low during the rest of fruit development. The effects of increase in carbohydrate availability during fruit growth were characterized. Increase in carbohydrate availability enhanced fruit growth largely through an increase in cell production. Expression of MdANT1 and MdANT2 increased sharply by up to around 5-fold in response to an increase in carbohydrate availability. Expression of the ANT genes was compared across two apple genotypes, 'Gala' and 'Golden Delicious Smoothee' (GS), which differ in the extent of fruit growth, largely due to differences in cell production. In comparison to 'Gala', the larger fruit-size genotype, GS, displayed higher levels and a longer duration of MdANT1 and MdANT2 expression. Expression of the ANTs and cell cycle genes in the fruit core and cortex tissues isolated using laser capture microdissection was studied. During early fruit growth, expression of the MdANTs was higher within the cortex, the tissue that constitutes the majority of the fruit. Additionally, MdANT1 and MdANT2 expression was positively correlated with that of A- and B-type CYCLINS, B-type CYCLIN-DEPENDENT-KINASES (CDKBs) and MdDEL1. Multiple lines of evidence from this study suggest that MdANT1 and MdANT2 regulate cell production during fruit growth in apple. ANTs may coordinate the expression of

  1. The Marine Mammal Programme at the Prince Edward Islands: 38 ...

    African Journals Online (AJOL)

    The Marine Mammal Programme (MMP) conducts research on pinnipeds and killer whales Orcinus orca at Marion Island, Prince Edward Islands, under the auspices of the Mammal Research Institute, Department of Zoology and Entomology, University of Pretoria. The history of the MMP, which has benefited from ...

  2. A comparative study on the magnetic and electrical properties of MFe12O19 (M=Ba and Sr)/BiFeO3 nanocomposites

    Science.gov (United States)

    Ahmed, M. A.; Mansour, S. F.; Ismael, H.

    2015-03-01

    M-type hexaferrite (MFe12O19), M=Ba or Sr nanoparticles with hexagonal crystal structure have been successfully synthesized by a citrate auto-combustion method. BiFeO3 (BFO) was prepared by the flash auto-combustion technique. Different nanocomposites were prepared according to the formula [(1-X) MFe12O19+XBiFeO3; M=Ba or Sr, X=0.3, 0.4, 0.5 and 0.6]. The structure and morphology of the obtained nanocomposites have been determined by X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM). From the results, it is observed that the value of saturation magnetization decreases with increasing BFO content, which was mainly due to the contribution of the volume of the weak-magnetic BFO to the total sample volume.

  3. Julgeolekuekspert : unustage jutud Eesti palgaarmeest / Edward N. Luttwak ; interv. Peeter Kuimet

    Index Scriptorium Estoniae

    Luttwak, Edward N.

    2006-01-01

    USA julgeolekuanalüütik soovitab Venemaa naabruses oleval Eestil oma riigikaitse üles ehitada Soome eeskujul, ajateenistus peab olema kohustuslik, et vajaduse korral end ise kaitsta, sest NATO abi ei saabu automaatselt. Lisa: Edward Nicolae Luttwak

  4. "Let's get down to business: a validation study of the Psychopathic Personality Inventory among a sample of MBA students.".

    Science.gov (United States)

    Heinze, Peter; Allen, Rhianon; Magai, Carol; Ritzler, Barry

    2010-08-01

    While the Psychopathic Personality Inventory (PPI) has gained increasing attention as a measure of noncriminal psychopathy, absent has been research involving samples including business people. This study investigated the validity of the PPI with such a population by examining the association between psychopathic traits and moral decision-making among MBA students. Sixty-six MBA students were assessed using the PPI, the MACH-IV (a measure of Machiavellianism), the Ethical Position Questionnaire (EPQ), and the Defining Issues Test (DIT-2). Only PPI Machiavellian Egocentricity was associated with level of post-conventional moral reasoning. MACH-IV Machiavellianism was a stronger predictor of the Subjectivist ethical position than were PPI subscales. However, a combination of MACH-IV Machiavellianism and four PPI scales accounted for 46% of the variance in Subjectivism. Results suggested that Machiavellian Egocentricity and Machiavellianism are distinct constructs. Benning, Patrick, Hicks, Blonigen, & Krueger (2003)'s two factor model of the PPI was also supported. In general, the findings provided further validation for the PPI as a tool for assessing psychopathic traits among "mainstream" individuals, including business people.

  5. Invited commentary on 'Robert G Edwards and the Roman Catholic Church'.

    Science.gov (United States)

    Head, Ivan Francis

    2011-06-01

    In this issue of Reproductive BioMedicine Online, Benagiano, Carrara and Filippi have produced a clearly written and comprehensive account of why the Roman Catholic Church has not welcomed the award of the 2010 Nobel Prize in Physiology and Medicine to Dr Robert G Edwards for the development of human IVF. I commend the article for its clarity and lucidity but attempt to point out some areas where disagreement even with its nuanced opposition to IVF may be legitimate. I try to make some simple comments that explain why this is so and I suggest some areas to which contemporary theology and philosophy can commit itself. But it is good to see even a nuanced response to the work of Robert G Edwards rather than a blanket condemnation. Copyright © 2011 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.

  6. Burrowing Owl and Other Migratory Bird Mitigation for a Runway Construction Project at Edwards AFB

    OpenAIRE

    Hoehn, Amber L.; Hagan, Mark; Bratton, Mark

    2009-01-01

    Edwards Air Force Base (AFB) scheduled the construction of a runway in the spring of 2007. The runway would be in an area that contained migratory birds and their habitat. The construction project would be near Edwards AFB main runway and had the potential not only to impact species protected under the Migratory Bird Treaty Act (MBTA), including the burrowing owl (Athene cunicularia), but also to increase bird and wildlife–aircraft strike hazards in the active flightline areas. To discourage ...

  7. Apple MdACS6 Regulates Ethylene Biosynthesis During Fruit Development Involving Ethylene-Responsive Factor.

    Science.gov (United States)

    Li, Tong; Tan, Dongmei; Liu, Zhi; Jiang, Zhongyu; Wei, Yun; Zhang, Lichao; Li, Xinyue; Yuan, Hui; Wang, Aide

    2015-10-01

    Ethylene biosynthesis in plants involves different 1-aminocyclopropane-1-carboxylic acid synthase (ACS) genes. The regulation of each ACS gene during fruit development is unclear. Here, we characterized another apple (Malus×domestica) ACS gene, MdACS6. The transcript of MdACS6 was observed not only in fruits but also in other tissues. During fruit development, MdACS6 was initiated at a much earlier stage, whereas MdACS3a and MdACS1 began to be expressed at 35 d before harvest and immediateley after harvest, respectively. Moreover, the enzyme activity of MdACS6 was significantly lower than that of MdACS3a and MdACS1, accounting for the low ethylene biosynthesis in young fruits. Overexpression of MdACS6 (MdACS6-OE) by transient assay in apple showed enhanced ethylene production, and MdACS3a was induced in MdACS6-OE fruits but not in control fruits. In MdACS6 apple fruits silenced by the virus-induced gene silencing (VIGS) system (MdACS6-AN), neither ethylene production nor MdACS3a transcript was detectable. In order to explore the mechanism through which MdACS3a was induced in MdACS6-OE fruits, we investigated the expression of apple ethylene-responsive factor (ERF) genes. The results showed that the expression of MdERF2 was induced in MdACS6-OE fruits and inhibited in MdACS6-AN fruits. Yeast one-hybrid assay showed that MdERF2 protein could bind to the promoter of MdACS3a. Moreover, down-regulation of MdERF2 in apple flesh callus led to a decrease of MdACS3a expression, demonstrating the regulation of MdERF2 on MdACS3a. The mechanism through which MdACS6 regulates the action of MdACS3a was discussed. © The Author 2015. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  8. Using Existing Teams to Teach about Teams: How an MBA Course in Managing Teams Helps Students and the Program

    Science.gov (United States)

    Isabella, Lynn A.

    2005-01-01

    This article chronicles the unique manner in which a second-year MBA elective course in managing teams has been crafted using existing first-year learning teams as its core. The design and orchestration of this course are detailed, as are the challenges posed, in delivering a course that not only teaches about teams and team dynamics but does so…

  9. Translational mini-review series on vaccines: The Edward Jenner Museum and the history of vaccination.

    Science.gov (United States)

    Morgan, A J; Parker, S

    2007-03-01

    Edward Jenner's discovery of vaccination must rank as one of the most important medical advances of all time and is a prominent example of the power of rational enquiry being brought to bear during the Age of Enlightenment in 18th century Europe. In the modern era many millions of lives are saved each year by vaccines that work essentially on the same principles that were established by Edward Jenner more than 200 years ago. His country home in Berkeley, Gloucestershire, is where he carried out his work and where he spent most of his life. The building is now a museum in which the life and times of Jenner are commemorated including not only the discovery of smallpox vaccination but also his other important scientific contributions to natural history and medicine. The trustees of the Edward Jenner museum are committed to promoting the museum as a real and "virtual" educational centre that is both entertaining and informative.

  10. Bed-material entrainment and associated transportation infrastructure problems in streams of the Edwards Plateau, central Texas

    Science.gov (United States)

    Heitmuller, Franklin T.; Asquith, William H.

    2008-01-01

    The Texas Department of Transportation commonly builds and maintains low-water crossings (LWCs) over streams in the Edwards Plateau in Central Texas. LWCs are low-height structures, typically constructed of concrete and asphalt, that provide acceptable passage over seasonal rivers or streams with relatively low normal-depth flow. They are designed to accommodate flow by roadway overtopping during high-flow events. The streams of the Edwards Plateau are characterized by cobble- and gravel-sized bed material and highly variable flow regimes. Low base flows that occur most of the time occasionally are interrupted by severe floods. The floods entrain and transport substantial loads of bed material in the stream channels. As a result, LWCs over streams in the Edwards Plateau are bombarded and abraded by bed material during floods and periodically must be maintained or even replaced.

  11. 77 FR 17530 - Order Granting an Application of Edward Jones & Co. LLP Exemption From Exchange Act Section 11(d...

    Science.gov (United States)

    2012-03-26

    ...'') requested that the Securities and Exchange Commission (``Commission'') issue to Edward Jones an exemption... subject to the conditions contained in this order, is exempt from the new issue lending restriction of... SECURITIES AND EXCHANGE COMMISSION [Release No. 34-66624] Order Granting an Application of Edward...

  12. Teacher Education in Prince Edward Island. Occasional Papers No. 13.

    Science.gov (United States)

    Brehaut, Willard

    This booklet evaluates teacher education in Prince Edward Island and recommends some immediate changes. The evaluation was occasioned by the changing role of the teacher in the world today from being "the prime source," a position that causes inadequacies and insecurity, to being the guide of individual children through appropriate…

  13. Map Showing Geology and Hydrostratigraphy of the Edwards Aquifer Catchment Area, Northern Bexar County, South-Central Texas

    Science.gov (United States)

    Clark, Amy R.; Blome, Charles D.; Faith, Jason R.

    2009-01-01

    Rock units forming the Edwards and Trinity aquifers in northern Bexar County, Texas, are exposed within all or parts of seven 7.5-minute quadrangles: Bulverde, Camp Bullis, Castle Hills, Helotes, Jack Mountain, San Geronimo, and Van Raub. The Edwards aquifer is the most prolific ground-water source in Bexar County, whereas the Trinity aquifer supplies water for residential, commercial, and industrial uses for areas north of the San Antonio. The geologic map of northern Bexar County shows the distribution of informal hydrostratigraphic members of the Edwards Group and the underlying upper member of the Glen Rose Limestone. Exposures of the Glen Rose Limestone, which forms the Trinity aquifer alone, cover approximately 467 km2 in the county. This study also describes and names five informal hydrostratigraphic members that constitute the upper member of the Glen Rose Limestone; these include, in descending order, the Caverness, Camp Bullis, Upper evaporite, Fossiliferous, and Lower evaporite members. This study improves our understanding of the hydrogeologic connection between the two aquifers as it describes the geology that controls the infiltration of surface water and subsurface flow of ground water from the catchment area (outcropping Trinity aquifer rocks) to the Edwards water-bearing exposures.

  14. Creating and Implementing an Offshore Graduate Program: A Case Study of Leadership and Development of the Global Executive MBA Program

    Science.gov (United States)

    Herrera, Marisa L.

    2013-01-01

    This study applies the literature on leadership framing to the globalization of higher education to understand the development of the Global Executive MBA program at a large university. The purpose of the study was to provide administrators, educators and university leaders an understanding as to how to respond to globalization and, secondly, to…

  15. Enhancing Undergraduates' Capabilities through Team-Based Competitions: The Edward Jones Challenge

    Science.gov (United States)

    Umble, Elisabeth J.; Umble, Michael; Artz, Kendall

    2008-01-01

    The Edward Jones Company recently initiated financial sponsorship of team-based competitions in six undergraduate business core classes at Baylor University. The challenges were chosen to take place in an introductory freshman business class, Managerial Accounting, Principles of Marketing, Corporate Finance, Operations Management, and Strategic…

  16. MD290: Q4 IP6 Quench Level

    CERN Document Server

    Bednarek, Mateusz Jakub; Lechner, Anton; CERN. Geneva. ATS Department

    2016-01-01

    The detailed program proposed for the LHC Machine Development concerning a quench induced by fast losses on the MQY.4L6 quadrupole is presented. The merit of the MD, the necessary modifications of the machine protection systems are presented together with a preliminary analysis of the MD results.

  17. Chosen-Prefix Collisions for MD5 and Applications

    NARCIS (Netherlands)

    M.M.J. Stevens (Marc); A.K. Lenstra (Arjen); B. de Weger (Benne)

    2012-01-01

    textabstractWe present a novel, automated way to find differential paths for MD5. Its main application is in the construction of \\emph{chosen-prefix collisions}. We have shown how, at an approximate expected cost of $2^{39}$ calls to the MD5 compression function, for any two chosen

  18. Dynamic data analysis of climate and recharge conditions over time in the Edwards Aquifer, Texas

    Science.gov (United States)

    Pierce, S. A.; Collins, J.; Banner, J.

    2017-12-01

    Understanding the temporal patterns in datasets related to climate, recharge, and water resource conditions is important for informing water management and policy decisions. Data analysis and pipelines for evaluating these disparate sources of information are challenging to set up and rely on emerging informatics tools to complete. This project gathers data from both historical and recent sources for the Edwards Aquifer of central Texas. The Edwards faces a unique array of challenges, as it is composed of karst limestone, is susceptible to contaminants and climate change, and is expected to supply water for a rapidly growing population. Given these challenges, new approaches to integrating data will be particularly important. Case study data from the Edwards is used to evaluate aquifer and hydrologic system conditions over time as well as to discover patterns and possible relationships across the information sources. Prior research that evaluated trends in discharge and recharge of the aquifer is revisited by considering new data from 1992-2015, and the sustainability of the Edwards as a water resource within the more recent time period is addressed. Reusable and shareable analytical data pipelines are constructed using Jupyter Notebooks and Python libraries, and an interactive visualization is implemented with the information. In addition to the data sources that are utilized for the water balance analyses, the Global Surface Water Monitoring System from the University of Minnesota, a tool that integrates a wide number of satellite datasets with known surface water dynamics and machine learning, is used to evaluate water body persistence and change over time at regional scales. Preliminary results indicate that surface water body over the Edwards with differing aerial extents are declining, excepting some dam-controlled lakes in the region. Other existing tools and machine learning applications are also considered. Results are useful to the Texas Water Research

  19. Oral Communication Skills Assessment in a Synchronous Hybrid MBA Programme: Does Attending Face-to-Face Matter for US and International Students?

    Science.gov (United States)

    Butz, Nikolaus T.; Askim-Lovseth, Mary K.

    2015-01-01

    The ability to communicate effectively is an essential skill for graduates of Masters of Business Administration (MBA) programmes; however, as synchronous hybrid learning becomes more common, business schools may find it challenging to assess students' proficiency in this core area. An additional layer of complexity is added by the burgeoning…

  20. Assessing the allelotypic effect of two aminocyclopropane carboxylic acid synthase-encoding genes MdACS1 and MdACS3a on fruit ethylene production and softening in Malus

    Science.gov (United States)

    Dougherty, Laura; Zhu, Yuandi; Xu, Kenong

    2016-01-01

    Phytohormone ethylene largely determines apple fruit shelf life and storability. Previous studies demonstrated that MdACS1 and MdACS3a, which encode 1-aminocyclopropane-1-carboxylic acid synthases (ACS), are crucial in apple fruit ethylene production. MdACS1 is well-known to be intimately involved in the climacteric ethylene burst in fruit ripening, while MdACS3a has been regarded a main regulator for ethylene production transition from system 1 (during fruit development) to system 2 (during fruit ripening). However, MdACS3a was also shown to have limited roles in initiating the ripening process lately. To better assess their roles, fruit ethylene production and softening were evaluated at five time points during a 20-day post-harvest period in 97 Malus accessions and in 34 progeny from 2 controlled crosses. Allelotyping was accomplished using an existing marker (ACS1) for MdACS1 and two markers (CAPS866 and CAPS870) developed here to specifically detect the two null alleles (ACS3a-G289V and Mdacs3a) of MdACS3a. In total, 952 Malus accessions were allelotyped with the three markers. The major findings included: The effect of MdACS1 was significant on fruit ethylene production and softening while that of MdACS3a was less detectable; allele MdACS1–2 was significantly associated with low ethylene and slow softening; under the same background of the MdACS1 allelotypes, null allele Mdacs3a (not ACS3a-G289V) could confer a significant delay of ethylene peak; alleles MdACS1–2 and Mdacs3a (excluding ACS3a-G289V) were highly enriched in M. domestica and M. hybrid when compared with those in M. sieversii. These findings are of practical implications in developing apples of low and delayed ethylene profiles by utilizing the beneficial alleles MdACS1-2 and Mdacs3a. PMID:27231553

  1. Swiss national MD-PhD-program: an outcome analysis.

    Science.gov (United States)

    Kuehnle, Katrin; Winkler, David T; Meier-Abt, Peter J

    2009-09-19

    This study aims at a first evaluation of the outcome of the Swiss national MD-PhD program during the last 16 years. One hundred and twenty six former and current students in the Swiss national MD-PhD program were surveyed via a Web-based questionnaire in September 2007. Twenty-four questions assessed information regarding participant demographics, information on the PhD thesis and publication activity, current positions and research activity, as well as participant's opinions, attitudes and career goals. Eighty questionnaires were received from 126 MD-PhD students and graduates (63.5% response rate). The responders consisted of present students (36%), former graduates (56%), and dropouts (8%). The percentage of women in the program was 23%, and the average duration of the program was 4.2 +/- 1.4 years. Research interests were predominantly in the fields of neuroscience, immunology, molecular biology and cancer research. A considerable portion of the MD-PhD graduates had an excellent publication record stemming from their PhD research work, and 89% were planning to continue a research-orientated career. Over 50% of those MD-PhD graduates completing their thesis before 2002 had already reached an assistant or full professor position at the time of the survey. Nearly all participants considered the MD-PhD training helpful to their career and high quality standards were assigned to the acquired practical and intellectual skills. However, criticism was expressed concerning the general mentoring and the career related mentoring. Moreover, general mentoring and career related mentoring were significantly less well perceived in research groups employing more than seven PhD students at the same time. The MD-PhD students and graduates surveyed were satisfied with their education and most of them continued a research-orientated career. Regarding the overall positive evaluation, this study supports the view that MD-PhD graduates are well qualified for a successful career in

  2. 1995 Edward teller lecture. Patience and optimism

    International Nuclear Information System (INIS)

    Miley, G.H.

    1996-01-01

    Remarks made in the author close-quote s acceptance lecture for the 1995 Edward Teller Medal are presented and expanded. Topics covered include research on nuclear-pumped lasers, the first direct e-beam-pumped laser, direct energy conversion and advanced fuel fusion, plus recent work on inertial electrostatic confinement. open-quote open-quote Patience close-quote close-quote and open-quote open-quote optimism close-quote close-quote are viewed as essential elements needed by scientists following the open-quote open-quote zig-zag close-quote close-quote path to fusion energy production. copyright 1996 American Institute of Physics

  3. Edward Cullen: el nuevo concepto de vampiro

    OpenAIRE

    Graillet Carrasco, Yolanda de

    2010-01-01

    El vampiro, como esa parte de sombra del inconsciente, evoluciona de diablo a ángel como se manifiesta en Crepúsculo de Stephenie Meyer. Para analizar este proceso, se traza el paso del vampiro moderno al post-moderno a través de tres figuras básicas: Drácula, Lestat y Edward Cullen, con la ayuda de los conceptos de Jung de sombra y héroe, y la teoría del cerebro triuno de McLean. Sangre, alma y sexo se desarrollan con este nuevo concepto de vampiro que comienza a revelar su reflejo para deja...

  4. Edward Cullen : el nuevo concepto de vampiro

    OpenAIRE

    Graillet Carrasco, Yolanda de

    2010-01-01

    El vampiro, como esa parte de sombra del inconsciente, evoluciona de diablo a ángel como se manifiesta en Crepúsculo de Stephenie Meyer. Para analizar este proceso, se traza el paso del vampiro moderno al post-moderno a través de tres figuras básicas: Drácula, Lestat y Edward Cullen, con la ayuda de los conceptos de Jung de sombra y héroe, y la teoría del cerebro triuno de McLean. Sangre, alma y sexo se desarrollan con este nuevo concepto de vampiro que comienza a revelar su reflejo para deja...

  5. Optimization of Edwards vacuum coating unit model E12E for the production of thin films

    International Nuclear Information System (INIS)

    Ruiz P, H.S.

    1995-01-01

    This work is about an Edwards vacuum coating unit model E12E, it shows the principle of vacuum thermal evaporation, some observations in the operation of vacuum diffusion pumps, mechanical pumps, vacuum gauge, Penning and Pirani, and some equations of leak vacuum, after the modifications and additions of Edwards vacuum coating unit for optimization, the last part contains a concise introduction about thin films and one specific application, it also contains the recommendations and requirements to keep the system in good conditions. (Author)

  6. Edward A. Bouchet

    Science.gov (United States)

    Mickens, R. E.

    2002-04-01

    Edward A. Bouchet was the first African American to receive the doctorate in any field of knowledge in the United States and that area was physics. He was granted the degree in 1876 from Yale University making him at that time one of the few persons to hold the physics doctorate from an American university. His prior education included the Hopkins Grammar School and Yale College (BA in 1874). After Yale, Bouchet taught mathematics, physics, and chemistry for over twenty-five years at the Institute for Colored Youth in Philadelphia. During the following two decades, he was employed in positions ranging from high school principal to employment by the federal government. Bouchet played a significant role in the education of African Americans through his teaching and mentoring activities. He was one among a small group of African Americans who achieved advanced training and education within decades of the American civil war. These individuals provided direction, leadership, and role models for what eventually became the civil/human rights movements. The year 2001 marks the 125th celebration of his receiving the doctorate. We present details of his life and career with an emphasis on the influence of the political and social forces exerted on him by society.

  7. A comparative study on the magnetic and electrical properties of MFe{sub 12}O{sub 19} (M=Ba and Sr)/BiFeO{sub 3} nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Ahmed, M.A., E-mail: moala47@hotmail.com [Materials Science Lab (1), Physics Department, Faculty of Science, Cairo University, Giza (Egypt); Mansour, S.F. [Physics Department, Faculty of Science, Zagazig University (Egypt); Ismael, H. [Materials Science Lab (1), Physics Department, Faculty of Science, Cairo University, Giza (Egypt)

    2015-03-15

    M-type hexaferrite (MFe{sub 12}O{sub 19}), M=Ba or Sr nanoparticles with hexagonal crystal structure have been successfully synthesized by a citrate auto-combustion method. BiFeO{sub 3} (BFO) was prepared by the flash auto-combustion technique. Different nanocomposites were prepared according to the formula [(1−X) MFe{sub 12}O{sub 19}+XBiFeO{sub 3}; M=Ba or Sr, X=0.3, 0.4, 0.5 and 0.6]. The structure and morphology of the obtained nanocomposites have been determined by X-ray diffraction (XRD) and field emission scanning electron microscopy (FESEM). From the results, it is observed that the value of saturation magnetization decreases with increasing BFO content, which was mainly due to the contribution of the volume of the weak-magnetic BFO to the total sample volume. - Highlights: • M-type nanohexaferrite (MFe{sub 12}O{sub 19}) as M=Ba and Sr powders were synthesized by the citrate autocombustion method. • The lattice parameters of composite were negligibly smaller than those of M-type. • FESEM showed that the samples were hexagonal plate-like shape. • M{sub s}, M{sub r}, μ{sub eff.} and H{sub C} were improved to be suitable for perpendicular high density recording media. • ε′ increased with BFO ratio which is useful in microwave devices.

  8. Réexaminer le modèle des «cinq forces de Porter»: La fusion des écoles et la formation de MBA jointe en tant que contrepartie du modèle d’avantage concurrentiel

    OpenAIRE

    Thi Thu Tra Nguyen

    2015-01-01

    In the scope of our doctoral research, business education is considered as an industry where business schools act as firms. Our thesis focuses on the strategic management field, with aims to explore how schools revisit their MBA curricula. Within this framework, joint and merged MBA programmes have been analysed as a counter point of Porter’s five forces (1980): rivalry among competitors, entry barriers, substitutions’ threats, buyers’ and suppliers’ bargaining power. The objective of this co...

  9. "I Understood the Words but I Didn't Know What They Meant": Japanese Online MBA Students' Experiences of British Assessment Practices

    Science.gov (United States)

    Fenton-O'Creevy, Mark; van Mourik, Carien

    2016-01-01

    We report on a case study of high Japanese student failure rates in an online MBA programme. Drawing on interviews, and reviews of exam and assignment scripts we frame the problems faced by these students in terms of a "language as social practice" approach and highlight the students' failure to understand the specific language games…

  10. MBA Students' Quality Improvement: The Correlation Analysis of Students' Personal Traits and Attitudes towards Teaching Methods at a Chinese University

    Science.gov (United States)

    Kong, Rui; Gao, Xiaowei; Zhong, Wanxing; Zhou, Xiaoling

    2015-01-01

    MBA education has become the fastest growing segment of education in China in recent years and a segment that can now be considered indispensable. However, how best to teach it has long been a source of debate. One of the key issues is how to match student traits with teaching methods. While engaged as teachers of marketing management, the authors…

  11. Bedrock geology and hydrostratigraphy of the Edwards and Trinity aquifers within the Driftwood and Wimberley 7.5-minute quadrangles, Hays and Comal Counties, Texas

    Science.gov (United States)

    Clark, Allan K.; Morris, Robert R.

    2017-11-16

    The Edwards and Trinity aquifers are major sources of water in south-central Texas and are both classified as major aquifers by the State of Texas. The population in Hays and Comal Counties is rapidly growing, increasing demands on the area’s water resources. To help effectively manage the water resources in the area, refined maps and descriptions of the geologic structures and hydrostratigraphic units of the aquifers are needed. This report presents the detailed 1:24,000-scale bedrock hydrostratigraphic map as well as names and descriptions of the geologic and hydrostratigraphic units of the Driftwood and Wimberley 7.5-minute quadrangles in Hays and Comal Counties, Tex.Hydrostratigraphically, the rocks exposed in the study area represent a section of the upper confining unit to the Edwards aquifer, the Edwards aquifer, the upper zone of the Trinity aquifer, and the middle zone of the Trinity aquifer. In the study area, the Edwards aquifer is composed of the Georgetown Formation and the rocks forming the Edwards Group. The Trinity aquifer is composed of the rocks forming the Trinity Group. The Edwards and Trinity aquifers are karstic with high secondary porosity along bedding and fractures. The Del Rio Clay is a confining unit above the Edwards aquifer and does not supply appreciable amounts of water to wells in the study area.The hydrologic connection between the Edwards and Trinity aquifers and the various hydrostratigraphic units is complex because the aquifer system is a combination of the original Cretaceous depositional environment, bioturbation, primary and secondary porosity, diagenesis, and fracturing of the area from Miocene faulting. All of these factors have resulted in development of modified porosity, permeability, and transmissivity within and between the aquifers. Faulting produced highly fractured areas which allowed for rapid infiltration of water and subsequently formed solutionally enhanced fractures, bedding planes, channels, and caves that

  12. 76 FR 5686 - Drawbridge Operation Regulation; Pocomoke River, Pocomoke City, MD

    Science.gov (United States)

    2011-02-02

    ... Operation Regulation; Pocomoke River, Pocomoke City, MD AGENCY: Coast Guard, DHS. ACTION: Notice of... River, mile 15.6, at Pocomoke City, MD. The deviation restricts the operation of the draw span to.... The Route 675 Bridge across Pocomoke River, mile 15.6 at Pocomoke City MD, has a vertical clearance in...

  13. 76 FR 48898 - Robert Leigh Kale, M.D., Decision and Order

    Science.gov (United States)

    2011-08-09

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Robert Leigh Kale, M.D., Decision and Order... Enforcement Administration, issued an Order to Show Cause to Robert Leigh Kale, M.D. (Registrant), of Fort... Certificate of Registration, BK9514375, issued to Robert Leigh Kale, M.D., be, and it hereby is, revoked. I...

  14. Transfemoral implantation of an Edwards SAPIEN valve in a tricuspid bioprosthesis without fluoroscopic landmarks.

    Science.gov (United States)

    Calvert, Patrick A; Himbert, Dominique; Brochet, Eric; Radu, Costin; Iung, Bernard; Hvass, Ulrik; Darondel, Jean-Marc; Depoix, Jean-Pol; Nataf, Patrick; Vahanian, Alec

    2012-03-01

    We describe the first report of an Edwards SAPIEN valve implanted in a tricuspid bioprosthesis from the femoral vein. We highlight the feasibility of this previously avoided approach and the techniques involved. A 61-year-old woman with multiple valve replacements for rheumatic heart disease presented with NHYA IV dyspnoea secondary to a severely stenosed tricuspid bioprosthesis. After failed aggressive medical therapy and surgical turn down, an Edwards SAPIEN XT valve was deployed in the tricuspid bioprosthesis via the right femoral vein. Adaptations to the standard transfemoral transcatheter aortic valve implantation (TAVI) technique included: (1) crossing the tricuspid bioprosthesis with a balloon floatation catheter; (2) temporary pacing wire in the coronary sinus rather than the right ventricle; (3) mounting of the SAPIEN XT valve in the reverse orientation to transfemoral TAVI; and (4) fine positioning of the final valve position pre-deployment by 3D transoesophageal echocardiography (3D TOE) alone due to complete radiolucency of the tricuspid bioprosthesis. The procedure was completed without complication and resulted in significant symptomatic improvement. Deployment of an Edwards SAPIEN valve in a tricuspid bioprosthesis via the femoral vein is feasible and, with careful adaptations to established TAVI techniques, can be performed without complications and with good clinical response.

  15. A Psychometric Assessment of the "Businessweek," "U.S. News & World Report," and "Financial Times" Rankings of Business Schools' MBA Programs

    Science.gov (United States)

    Iacobucci, Dawn

    2013-01-01

    This research investigates the reliability and validity of three major publications' rankings of MBA programs. Each set of rankings showed reasonable consistency over time, both at the level of the overall rankings and for most of the facets from which the rankings are derived. Each set of rankings also showed some levels of convergent and…

  16. 76 FR 20032 - Thomas E. Mitchell, M.D.; Dismissal of Proceeding

    Science.gov (United States)

    2011-04-11

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 10-7] Thomas E. Mitchell, M.D... Control, Drug Enforcement Administration, issued an Order to Show Cause to Thomas E. Mitchell, M.D....100(b) and 0.104, I hereby order that the Order to Show Cause issued to Thomas E. Mitchell, M.D., be...

  17. Edward Lee Thorndike and John Dewey on the Science of Education.

    Science.gov (United States)

    Tomlinson, Stephen

    1997-01-01

    Reviews the contributions of Edward Thorndike and John Dewey to U.S. educational theory. Notes that both believed teaching could be transformed into a science, but disagreed in their views of human nature. Discusses the failings of Thorndike's program in U.S. schools and the implications of Dewey's arguments for educational practice. (DSK)

  18. MBA 教育项目的营销策略组合研究——以华侨大学为例%Study on the Marketing Strategy Combination of the MBA Education Project——Taking the Huaqiao University as an Example

    Institute of Scientific and Technical Information of China (English)

    戴敏敏

    2012-01-01

      Marketing strategy of Chinese MBA education project at the University of studies mainly includes part 3 of the combination of content, that is submitted by market segmentation, market positioning and marketing strategies. This three-part time with a close logical relationship among the most prominent is that marketing mix strategy based on market segmentation and market position that contains basic marketing strategies and strengthening of the class based on the 4P class 4C-based marketing strategies.%  华侨大学 MBA 教育项目的营销策略组合的研究主要包括三部分内容,即市场细分、市场定位和提出营销策略组合。这三部分内容具有紧密的时间逻辑关系,其中最为突出之处在于营销组合策略基于市场细分和市场定位包含基础类基于4P 的营销策略组合和加强类基于4C 营销策略组合。

  19. 77 FR 7182 - Scott W. Houghton, M.D.; Decision and Order

    Science.gov (United States)

    2012-02-10

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 12-09] Scott W. Houghton, M.D... CFR 0.100(b), I order that DEA Certificate of Registration BH8796077, issued to Scott W. Houghton, M.D., be, and it hereby is, revoked. I further order that any pending application of Scott W. Houghton, M.D...

  20. Do, but Don't Tell: The Search for Social Responsibility and Sustainability in the Websites of the Top-100 US MBA Programs

    Science.gov (United States)

    Hart, Timothy A.; Fox, Corey J.; Ede, Kenneth F.; Korstad, John

    2015-01-01

    Purpose: The purpose of this study is to investigate the degree to which business schools, in particular MBA programs, have developed academic programs and centers specifically focused on corporate social responsibility and sustainability (CSRS) and, for those that have, promote them on their Web sites. The instruction of CSRS in institutions of…

  1. Relationships Between the Vocational Preference Inventory and the Edwards Personal Preference Schedule

    Science.gov (United States)

    Wakefield, James A., Jr.; Cunningham, Claude H.

    1975-01-01

    The Vocational Preference Inventory and the Edwards Personal Preference Schedule were administered to 372 undergraduates. The two instruments were compared using canonical analysis. The analysis revealed three significant relationships between components of the two instruments. The relationships were viewed as supportive of Holland's theory of…

  2. Stealing the gold a celebration of the pioneering physics of Sam Edwards

    CERN Document Server

    Goldenfeld, Nigel; Sherrington, D C; Edwards, S F

    2004-01-01

    This title presents a survey of some of the most exciting topics in condensed matter physics today, from the perspective of the pioneering work of Sam Edwards. Original articles from leaders in the field highlight the historical development as well as new and emerging areas.

  3. Developing improved MD codes for understanding processive cellulases

    International Nuclear Information System (INIS)

    Crowley, M F; Nimlos, M R; Himmel, M E; Uberbacher, E C; Iii, C L Brooks; Walker, R C

    2008-01-01

    The mechanism of action of cellulose-degrading enzymes is illuminated through a multidisciplinary collaboration that uses molecular dynamics (MD) simulations and expands the capabilities of MD codes to allow simulations of enzymes and substrates on petascale computational facilities. There is a class of glycoside hydrolase enzymes called cellulases that are thought to decrystallize and processively depolymerize cellulose using biochemical processes that are largely not understood. Understanding the mechanisms involved and improving the efficiency of this hydrolysis process through computational models and protein engineering presents a compelling grand challenge. A detailed understanding of cellulose structure, dynamics and enzyme function at the molecular level is required to direct protein engineers to the right modifications or to understand if natural thermodynamic or kinetic limits are in play. Much can be learned about processivity by conducting carefully designed molecular dynamics (MD) simulations of the binding and catalytic domains of cellulases with various substrate configurations, solvation models and thermodynamic protocols. Most of these numerical experiments, however, will require significant modification of existing code and algorithms in order to efficiently use current (terascale) and future (petascale) hardware to the degree of parallelism necessary to simulate a system of the size proposed here. This work will develop MD codes that can efficiently use terascale and petascale systems, not just for simple classical MD simulations, but also for more advanced methods, including umbrella sampling with complex restraints and reaction coordinates, transition path sampling, steered molecular dynamics, and quantum mechanical/molecular mechanical simulations of systems the size of cellulose degrading enzymes acting on cellulose

  4. Trends in MD/PhD Graduates Entering Psychiatry: Assessing the Physician-Scientist Pipeline.

    Science.gov (United States)

    Arbuckle, Melissa R; Luo, Sean X; Pincus, Harold Alan; Gordon, Joshua A; Chung, Joyce Y; Chavez, Mark; Oquendo, Maria A

    2018-06-01

    The goal of this study was to identify trends in MD/PhD graduates entering psychiatry, to compare these trends with other specialties, and to review strategies for enhancing the physician-scientist pipeline. Data on 226,588 medical students graduating from Liaison Committee on Medical Education accredited programs between 1999 and 2012 (6626 MD/PhDs) were used to evaluate the number, percentage, and proportion of MD/PhDs entering psychiatry in comparison with other specialties (neurology, neurosurgery, internal medicine, family medicine, and radiation oncology). Linear regression and multiple linear regression determined whether these values increased over time and varied by sex. Over 14 years, an average of 18 MD/PhDs (range 13-29) enrolled in psychiatry each year. The number of MD/PhDs going into psychiatry significantly increased, although these gains were modest (less than one additional MD/PhD per year). The proportion of students entering psychiatry who were MD/PhDs varied between 2.9 and 5.9 per 100 residents, with no significant change over time. There was also no change in the percentage of MD/PhDs entering psychiatry from among all MD/PhD graduates. The rate of increase in the number of MD/PhDs going into psychiatry did not differ significantly from other specialties except for family medicine, which is decreasing. The rate of MD/PhDs going into psychiatry was higher for women, suggesting closure of the sex gap in 17 years. Despite the increase in the number of MD/PhDs entering psychiatry, these numbers remain low. Expanding the cohort of physician-scientists dedicated to translational research in psychiatry will require a multipronged approach.

  5. Characterization of an Autophagy-related Gene MdATG8i from apple

    Directory of Open Access Journals (Sweden)

    Ping eWang

    2016-05-01

    Full Text Available Nutrient deficiencies restrict apple (Malus sp. tree growth and productivity in Northwest China. The process of autophagy, a conserved degradation pathway in eukaryotic cells, has important roles in nutrient-recycling and helps improve plant performance during periods of nutrient-starvation. Little is known about the functioning of autophagy-related genes (ATGs in apple. In this study, one of the ATG8 gene family members MdATG8i was isolated from M. domestica. MdATG8i has conserved putative tubulin binding sites and ATG7 interaction domains. A 1865-bp promoter region cloned from apple genome DNA was predicated to have cis-regulatory elements responsive to light, environmental stresses and hormones. MdATG8i transcriptions were induced in response to leaf senescence, nitrogen depletion, and oxidative stress. At cellular level, MdATG8i protein was expressed in the nucleus and cytoplasm of onion epidermal cells. Yeast two-hybrid tests showed that MdATG8i could interact with MdATG7a and MdATG7b. In Arabidopsis, its heterologous expression was associated with enhanced vegetative growth, leaf senescence, and tolerance to nitrogen- and carbon-starvation. MdATG8i-overexpressing ‘Orin’ apple callus lines also displayed improved tolerance to nutrient-limited conditions. Our results demonstrate that MdATG8i protein could function in autophagy in a conserved way, as a positive regulator in the response to nutrient-starvation.

  6. [MD PhD programs: Providing basic science education for ophthalmologists].

    Science.gov (United States)

    Spaniol, K; Geerling, G

    2015-06-01

    Enrollment in MD PhD programs offers the opportunity of a basic science education for medical students and doctors. These programs originated in the USA where structured programs have been offered for many years, but now German universities also run MD PhD programs. The MD PhD programs provided by German universities were investigated regarding entrance requirements, structure and financing modalities. An internet and telephone-based search was carried out. Out of 34 German universities 22 offered MD PhD programs. At 15 of the 22 universities a successfully completed course of studies in medicine was required for enrollment, 7 programs admitted medical students in training and 7 programs required a medical doctoral thesis, which had to be completed with at least a grade of magna cum laude in 3 cases. Financing required scholarships in many cases. Several German universities currently offer MD PhD programs; however, these differ considerably regarding entrance requirements, structure and financing. A detailed analysis investigating the success rates of these programs (e.g. successful completion and career paths of graduates) would be of benefit.

  7. Porter’s five forces reconsideration: Model of joint MBA programmes and schools’ fusion in the industry of Management Education as a counter point of competitive environment model : COMMUNICATION POUR LA BIENNALE 2015 « COOPERER » Identifiant : N° 448

    OpenAIRE

    NGUYEN , Thi Thu Tra

    2015-01-01

    International audience; In the scope of our doctoral research, business education is considered as an industry where business schools act as firms. Our thesis focuses on the strategic management field, with aims to explore how schools revisit their MBA curricula. Within this framework, joint and merged MBA programmes have been analysed as a counter point of Porter’s five forces (1980): rivalry among competitors, entry barriers, substitutions’ threats, buyers’ and suppliers’ bargaining power. ...

  8. De eerste 'European Day Without A Road Death' : maak kennis met EDWARD.

    NARCIS (Netherlands)

    Preusting, G.

    2016-01-01

    Op 21 september 2016 vond de eerste European Day Without A Road Death plaats. Het project - naar goed Europees gebruik met een acronym 'EDWARD' gedoopt - is een initiatief van TISPOL, het European Traffic Police Network. TISPOL, waarbij dertig landen zijn aangesloten, vraagt nu aan elke Europese

  9. MaMBA - a functional Moon and Mars Base Analog

    Science.gov (United States)

    Heinicke, C.; Foing, B.

    2017-09-01

    Despite impressive progress in robotic exploration of celestial bodies, robots are believed to never reach the effectiveness and efficiency of a trained human. Consequently, ESA proposes to build an international Moon Village in roughly 15 years and NASA plans for the first manned mission to Mars shortly after. One of the challenges still remaining is the need for a shelter, a habitat which allows human spacefarers to safely live and work on the surface of a celestial body. Although a number of prototype habitats has been built during the last decades and inhabited for various durations (e.g. MDRS, FMARS, HI-SEAS, M.A.R.S.), these habitats are typically equipped for studies on human factors and would not function in an extraterrestrial environment. Project MaMBA (Moon and Mars Base Analog) aims to build the first functional habitat based on the lessons learned from intermediate and long duration missions at the mentioned habitats. The habitat will serve for testing technologies like life support, power systems, and interplanetary communi­cation. Special attention will be given to the develop­ment of the geoscience laboratory module. Crews will live and work inside the habitat to ensure its functionality.

  10. The distribution and spread of alien vascular plants on Prince Edward Island

    NARCIS (Netherlands)

    Ryan, P.G.; Smith, V.; Gremmen, N.J.M.

    2003-01-01

    Surveys of alien plants at subantarctic Prince Edward Island in 2001 show that the ranges of all three introduced species have increased since the last survey in 1998. Poa annua, the longest-established species, increased its range substantially after 1987, prior to which it was confined to a single

  11. 3MdB: the Mexican Million Models database

    Science.gov (United States)

    Morisset, C.; Delgado-Inglada, G.

    2014-10-01

    The 3MdB is an original effort to construct a large multipurpose database of photoionization models. This is a more modern version of a previous attempt based on Cloudy3D and IDL tools. It is accessed by MySQL requests. The models are obtained using the well known and widely used Cloudy photoionization code (Ferland et al, 2013). The database is aimed to host grids of models with different references to identify each project and to facilitate the extraction of the desired data. We present here a description of the way the database is managed and some of the projects that use 3MdB. Anybody can ask for a grid to be run and stored in 3MdB, to increase the visibility of the grid and the potential side applications of it.

  12. Numerical analysis of the in-well vapor-stripping system demonstration at Edwards Air Force Base

    International Nuclear Information System (INIS)

    White, M.D.; Gilmore, T.J.

    1996-10-01

    Numerical simulations, with the Subsurface Transport Over Multiple Phases (STOMP) simulator, were applied to the field demonstration of an in-well vapor-stripping system at Edwards Air Force Base (AFB), near Mojave, California. The demonstration field site on the Edwards AFB was previously contaminated from traversing groundwater that was contained a varied composition of volatile organic compounds (VOCs), which primarily includes trichloroethylene (TCE). Contaminant TCE originated from surface basin that had been used to collect runoff during the cleaning of experimental rocket powered planes in the 1960s and 1970s. This report documents those simulations and associated numerical analyses. A companion report documents the in- well vapor-stripping demonstration from a field perspective

  13. Multi-Device to Multi-Device (MD2MD Content-Centric Networking Based on Multi-RAT Device

    Directory of Open Access Journals (Sweden)

    Cheolhoon Kim

    2017-11-01

    Full Text Available This paper proposes a method whereby a device can transmit and receive information using a beacon, and also describes application scenarios for the proposed method. In a multi-device to multi-device (MD2MD content-centric networking (CCN environment, the main issue involves searching for and connecting to nearby devices. However, if a device can’t find another device that satisfies its requirements, the connection is delayed due to the repetition of processes. It is possible to rapidly connect to a device without repetition through the selection of the optimal device using the proposed method. Consequently, the proposed method and scenarios are advantageous in that they enable efficient content identification and delivery in a content-centric Internet of Things (IoT environment, in which multiple mobile devices coexist.

  14. Apple F-box Protein MdMAX2 Regulates Plant Photomorphogenesis and Stress Response

    Directory of Open Access Journals (Sweden)

    Jian-Ping An

    2016-11-01

    Full Text Available MAX2 (MORE AXILLARY GROWTH2 is involved in diverse physiological processes, including photomorphogenesis, the abiotic stress response, as well as karrikin and strigolactone signaling-mediated shoot branching. In this study, MdMAX2, an F-box protein that is a homolog of Arabidopsis MAX2, was identified and characterized. Overexpression of MdMAX2 in apple calli enhanced the accumulation of anthocyanin. Ectopic expression of MdMAX2 in Arabidopsis exhibited photomorphogenesis phenotypes, including increased anthocyanin content and decreased hypocotyl length. Further study indicated that MdMAX2 might promote plant photomorphogenesis by affecting the auxin signaling as well as other plant hormones. Transcripts of MdMAX2 were noticeably up-regulated in response to NaCl and Mannitol treatments. Moreover, compared with the wild type, the MdMAX2-overexpressing apple calli and Arabidopsis exhibited increased tolerance to salt and drought stresses. Taken together, these results suggest that MdMAX2 plays a positive regulatory role in plant photomorphogenesis and stress response.

  15. A Recently Discovered Photograph of Edward Joshua Cooper of Markree (1797-1863)

    Science.gov (United States)

    Coffey, P.

    1998-01-01

    A photograph of Edward Joshua Cooper, as well as a collection of letters to his brother-in-law, George Burdett L'Estrange, have been found in papers belonging to the author's family. One letter mentions the Markree telescope. It is thought that this is the only extant photograph of Cooper.

  16. Waiting time distribution in M/D/1 queueing systems

    DEFF Research Database (Denmark)

    Iversen, Villy Bæk; Staalhagen, Lars

    1999-01-01

    The well-known formula for the waiting time distribution of M/D/1 queueing systems is numerically unsuitable when the load is close to 1.0 and/or the results for a large waiting time are required. An algorithm for any load and waiting time is presented, based on the state probabilities of M/D/1...

  17. 75 FR 49992 - Peter W.S. Grigg, M.D.; Revocation of Registration

    Science.gov (United States)

    2010-08-16

    ... DEPARTMENT OF JUSTICE Drug Enforcement Administration Peter W.S. Grigg, M.D.; Revocation of... Order to Show Cause and Immediate Suspension of Registration to Peter W.S. Grigg, M.D. (Respondent), of... Registration, BG2107856, issued to Peter W.S. Grigg, M.D., be, and it hereby is, revoked. This Order is...

  18. Kepentingan Rusia Dalam Memberikan Suaka Politik Kepada Edward Joseph Snowden

    OpenAIRE

    ", Ibrahim; Iskandar, Irwan

    2017-01-01

    This research to explain interest of Russia with Snowden. Edward Joseph Snowden is a former Central Intelligence Agency (CIA) employee and a former contractor for National Security Agency (NSA) who leaked classified information to The Guardian and The Washington Post. Snowden who leaked classified information have Surveillance program doing by United State of America. The Surveillance Program is a cooperate between 9 big companies from United States, which: Yahoo!, Facebook, Google, Apple, Sk...

  19. O humanismo crítico de Edward W. Said Edward W. Said's critical humanism

    Directory of Open Access Journals (Sweden)

    Marcos Costa Lima

    2008-01-01

    Full Text Available Este trabalho pretende fazer uma abordagem da obra de Edward Said capaz de aportar contribuições teóricas para o campo da Política Internacional. Para além de uma atualização do conceito de imperialismo, central em sua obra, quatro outros temas tratados por ele nos interessam aqui diretamente: o primeiro é o presente poder hegemônico exercido pelo governo dos Estados Unidos desde o fim da Segunda Guerra Mundial e que nos interpela sobre os desafios de uma interdependência transnacional, sobre a construção de uma ordem mundial efetivamente democrática. O segundo tema é a questão nacional, quando o autor aponta os riscos de uma consciência nacional despreparada ou ainda desvirtuada após as lutas de independência e libertação. O terceiro é a sua revolta com os estereótipos e preconceitos contra a civilização árabe-muçulmana, também vinculada à ignorância ocidental sobre esta cultura, sobre suas contribuições. Em quarto lugar, a visibilidade que dá à contribuição intelectual periférica de autores como Eqbal Ahmad (paquistanês, Ngugi Wa Thongo (queniano, Ali Shariat (iraniano, Wole Soyinka (nigeriano, C. L. R. James (de Trinidad-Tobago, Faiz Ahmada Faiz (paquistanês, José Martí (cubano, Ranajit Guha (indiano, Aimé Césaire (martiniquenho, entre outros.This paper intends to present an approach to Edward Said's work and to give some light to his unexpected theoretical contributions for International Politics. Beyond the effort of updating the concept of imperialism, central in his premises, five others themes among his books interest us directly. The first one is the present hegemonic power exerted by the USA government since the Second World War, that interrogates us about the possibilities to build an effectively democratic world order. The second is about the national question, where the author points out the risks of an unprepared national conscience or still depreciated after the fights for independence and

  20. Southern Stalemate: Five Years without Public Education in Prince Edward County, Virginia

    Science.gov (United States)

    Bonastia, Christopher

    2012-01-01

    In 1959, Virginia's Prince Edward County closed its public schools rather than obey a court order to desegregate. For five years, black children were left to fend for themselves while the courts decided if the county could continue to deny its citizens public education. Investigating this remarkable and nearly forgotten story of local, state, and…

  1. Developing the MD Explorer

    Science.gov (United States)

    Howie, Philip V.

    1993-04-01

    The MD Explorer is an eight-seat twin-turbine engine helicopter which is being developed using integrated product definition (IPD) team methodology. New techniques include NOTAR antitorque system for directional control, a composite fuselage, an all-composite bearingless main rotor, and digital cockpit displays. Three-dimensional CAD models are the basis of the entire Explorer design. Solid models provide vendor with design clarification, removing much of the normal drawing interpretation errors.

  2. MD Anderson's Population Health Approaches to Cancer Prevention.

    Science.gov (United States)

    Foxhall, Lewis; Moreno, Mark; Hawk, Ernest

    2018-02-01

    Texas's size and unique population demographics present challenges to addressing the state's cancer burden. The University of Texas MD Anderson Cancer Center is one of 69 National Cancer Institute-designated cancer centers across the United States. While these centers traditionally have focused on research, education and training, and providing research-driven patient care, they are in a unique position to collaboratively advance population health through cancer control. Unlike the traditional academic model of a three-legged stool representing research, education, and patient care, MD Anderson's mission includes a fourth leg that incorporates population health approaches. MD Anderson has leveraged state- and national-level data and freely available resources to develop population-health priorities and a set of evidence-based actions across policy, public and professional education, and community-based clinical service domains to address these priorities. Population health approaches complement dissemination and implementation research and treatment, and will be increasingly needed to address the growing cancer burden in Texas and the nation.

  3. A case study of contaminants on military ranges: Camp Edwards, Massachusetts, USA

    International Nuclear Information System (INIS)

    Clausen, Jay; Robb, Joe; Curry, Diane; Korte, Nic

    2004-01-01

    An extensive investigation at the Camp Edwards, Massachusetts Military Reservation (MMR) demonstrates that assessment of groundwater and soil contamination at military ranges can be limited primarily to explosive-related compounds such as RDX, HMX, perchlorate, TNT and their transformation products. A modified analytical method is recommended to expand the list of explosives and to improve the detection limits. Analyses of metals, VOCs, SVOCs, and TICs are unnecessary. Soil samples may require the analyses of PAHs and PCNs for burn areas. Camp Edwards, as one of the few military ranges that have been exhaustively investigated for contaminants, is an ideal point of departure for evaluating other ranges. The permeable site soils promote leaching of contaminants and inhibit biotic and abiotic transformations. Moreover, the site has experienced an unusual extent of activities in its more than ninety years of active use. The recommendations in this report are based on data obtained for more than 200 analytes from more than 15,000 environmental samples. - Assessment of groundwater and soil contamination at US military ranges can be limited primarily to explosive-related compounds

  4. “Sex and the Island”: Lives of Single Women in Prince Edward Island

    Directory of Open Access Journals (Sweden)

    Kristie Collins

    2011-05-01

    Full Text Available This article considers the significance attributed to Prince Edward Island in managing a marginalized single female identity, as presented by accounts of thirty never-married and previously-married Island women, aged twenty-seven through sixty-five. As popular media and social narratives overwhelmingly position contemporary single women against an urban backdrop, the question arises as to whether unmarried Island women feel “marooned” in ways their urban counterparts may not. In accordance with feminist aims to produce research for, rather than about, women’s lives, the paper focuses on two themes from fieldwork interviews that were of particular interest to participants. The first theme relates to negotiating female singleness within the Island’s family-centered culture, and the second theme presents participants’ talk around advantages and disadvantages of living in Prince Edward Island, Canada, as single women. The paper concludes with a summary of other findings from the study and suggestions for future research on female singleness and island locales.

  5. 76 FR 17673 - Bienvenido Tan, M.D.; Denial of Application

    Science.gov (United States)

    2011-03-30

    ... (alprazolam) to help him sleep. Id. at 64. R.E. opted to buy the drugs from Respondent's dispensary and... DEPARTMENT OF JUSTICE Drug Enforcement Administration [Docket No. 09-12] Bienvenido Tan, M.D... Control, Drug Enforcement Administration, issued an Order to Show Cause to Bienvenido Tan, M.D...

  6. Evaluation of hydroacid complex in the forward osmosis–membrane distillation (FO–MD) system for desalination

    KAUST Repository

    Wang, Peng; Cui, Yue; Ge, Qingchun; Fern Tew, Tjin; Chung, Neal Tai-Shung

    2015-01-01

    The incorporation of membrane distillation (MD) into forward osmosis (FO) provides process sustainability to regenerate the draw solution and to produce clean water simultaneously. However, the reverse salt flux is the major hurdle in the FO-MD system because it not only reduces the effective osmotic driving force across the membrane but also increases the replenishment cost and scaling issue. For the first time, a hydroacid complex with abundant hydrophilic groups and ionic species is evaluated as the draw solutes in the hybrid FO-MD system consisting of multi-bore PVDF MD membranes for seawater/brackish desalination. In order to evaluate the practicality of the hydroacid complex in the FO-MD system, FO and MD experiments were conducted at elevated temperatures and concentrations. The hydroacid complex has displayed desired properties such as high solubility, low viscosity, excellent thermal stability and minimal reverse salt flux suitable for FO and MD operations. FO-MD desalination process was demonstrated with a highest seawater desalination flux of 6/32 LMH (FO/MD). This study may open up the prospective of employing the hydroacid complex as the draw solute in FO-MD hybrid systems for seawater /brackish desalination. © 2015 Elsevier B.V.

  7. Evaluation of hydroacid complex in the forward osmosis–membrane distillation (FO–MD) system for desalination

    KAUST Repository

    Wang, Peng

    2015-11-01

    The incorporation of membrane distillation (MD) into forward osmosis (FO) provides process sustainability to regenerate the draw solution and to produce clean water simultaneously. However, the reverse salt flux is the major hurdle in the FO-MD system because it not only reduces the effective osmotic driving force across the membrane but also increases the replenishment cost and scaling issue. For the first time, a hydroacid complex with abundant hydrophilic groups and ionic species is evaluated as the draw solutes in the hybrid FO-MD system consisting of multi-bore PVDF MD membranes for seawater/brackish desalination. In order to evaluate the practicality of the hydroacid complex in the FO-MD system, FO and MD experiments were conducted at elevated temperatures and concentrations. The hydroacid complex has displayed desired properties such as high solubility, low viscosity, excellent thermal stability and minimal reverse salt flux suitable for FO and MD operations. FO-MD desalination process was demonstrated with a highest seawater desalination flux of 6/32 LMH (FO/MD). This study may open up the prospective of employing the hydroacid complex as the draw solute in FO-MD hybrid systems for seawater /brackish desalination. © 2015 Elsevier B.V.

  8. Burkhardt : dividendi võimaldab välja võtta maksude optimeerimine / Edward Burkhardt ; interv. Andres Reimer

    Index Scriptorium Estoniae

    Burkhardt, Edward

    2002-01-01

    Eesti Raudtee nõukogu esimees Edward Burkhardt õigustab ettevõttest suuremahuliste dividendide väljavõtmist ja põhjendab seda maksude optimeerimisega. Kommenteerib majandusminister Liina Tõnisson

  9. Representation and Imperialism in Edward Said

    Directory of Open Access Journals (Sweden)

    Bruno Sciberras de Carvalho

    2010-12-01

    Full Text Available Based on the idea that culture and identities involve a politically built process, the importance of the concepts of representation and imperialism in the work of Edward Said is discussed. The article analyses two of the author’s general proposals. Firstly, the thesis of the centrality of cultural dimension in political relations, which leads to the review of postulates that consider culture as a mere reflection of a phenomena seen as essential or as a sphere isolated from the power practices. Secondly, the study examines how the author’s conception of imperialism is used as a means of identification that keep structures of authority and hegemony, which, in turn, may be defied by processes of resistance. Finally, the validity of the open character of Said’s political theory is debated, which encompasses both the power of representations and an action of political questioning.

  10. 77 FR 5201 - Drawbridge Operation Regulation; Bear Creek, Dundalk, MD

    Science.gov (United States)

    2012-02-02

    ...-AA09 Drawbridge Operation Regulation; Bear Creek, Dundalk, MD AGENCY: Coast Guard, DHS. ACTION: Notice... operation of the Baltimore County highway bridge at Wise Avenue across Bear Creek, mile 3.4, between Dundalk... Avenue across Bear Creek, mile 3.4 between Dundalk and Sparrows Point, MD. This change would require the...

  11. Analysis of MD5 authentication in various routing protocols using simulation tools

    Science.gov (United States)

    Dinakaran, M.; Darshan, K. N.; Patel, Harsh

    2017-11-01

    Authentication being an important paradigm of security and Computer Networks require secure paths to make the flow of the data even more secure through some security protocols. So MD-5(Message Digest 5) helps in providing data integrity to the data being sent through it and authentication to the network devices. This paper gives a brief introduction to the MD-5, simulation of the networks by including MD-5 authentication using various routing protocols like OSPF, EIGRP and RIPv2. GNS3 is being used to simulate the scenarios. Analysis of the MD-5 authentication is done in the later sections of the paper.

  12. Inversion Therapy: Can It Relieve Back Pain?

    Science.gov (United States)

    Inversion therapy: Can it relieve back pain? Does inversion therapy relieve back pain? Is it safe? Answers from Edward R. Laskowski, M.D. Inversion therapy doesn't provide lasting relief from back ...

  13. Alternative Education on Prince Edward Island: A Hybrid of "Mainstream" and Special Education

    Science.gov (United States)

    Thorne, Carolyn M.

    2017-01-01

    Alternative education programmes have acted as a disciplinary practice used by schools in Prince Edward Island (PEI), Canada, as a response to providing students, especially those identified with challenging behaviours, who do not fit into "mainstream" schools. This article highlights the emergence of alternative education in PEI and…

  14. Osmotically and thermally isolated forward osmosis-membrane distillation (fo-md) integrated module for water treatment applications

    KAUST Repository

    Ghaffour, Noreddine

    2016-09-01

    An integrated forward osmosis-membrane distillation (FO-MD) module and systems and methods incorporating the module is disclosed providing higher efficiencies and using less energy. The FO-MD module is osmotically and thermally isolated. The isolation can prevent mixing of FO draw solution/FO permeate and MD feed, and minimize dilution of FO draw solution and cooling of MD feed. The module provides MD feed solution and FO draw solution streams that flow in the same module but are separated by an isolation barrier. The osmotically and thermally isolated FO-MD integrated module, systems and methods offer higher driving forces of both FO and MD processes, higher recovery, and wider application than previously proposed hybrid FO- MD systems.

  15. Osmotically and thermally isolated forward osmosis-membrane distillation (fo-md) integrated module for water treatment applications

    KAUST Repository

    Ghaffour, NorEddine; Francis, Lijo; Li, Zhenyu; Valladares, Rodrigo; Alsaadi, Ahmad S.; Ghdaib, Muhannad Abu; Amy, Gary L.

    2016-01-01

    An integrated forward osmosis-membrane distillation (FO-MD) module and systems and methods incorporating the module is disclosed providing higher efficiencies and using less energy. The FO-MD module is osmotically and thermally isolated. The isolation can prevent mixing of FO draw solution/FO permeate and MD feed, and minimize dilution of FO draw solution and cooling of MD feed. The module provides MD feed solution and FO draw solution streams that flow in the same module but are separated by an isolation barrier. The osmotically and thermally isolated FO-MD integrated module, systems and methods offer higher driving forces of both FO and MD processes, higher recovery, and wider application than previously proposed hybrid FO- MD systems.

  16. Further contributions to the Hydradephaga (Coleoptera, Haliplidae, Gyrinidae and Dytiscidae) fauna of Prince Edward Island, Canada: new records, distributions and faunal composition.

    Science.gov (United States)

    Alarie, Yves

    2016-01-01

    The Haliplidae, Gyrinidae and Dytiscidae (Coleoptera) of Prince Edward Island, Canada were surveyed during the years 2004-2005. A total of 2450 individuals from 79 species were collected from 98 different localities, among which 30 species are newly recorded from that region. Among these, Acilius sylvanus Hilsenhoff, Rhantus consimilis Motschulsky and Neoporus sulcipennis (Fall) stand out as representing the easternmost reports of these species in Canada. Once removed, Gyrinus aquiris LeConte (Gyrinidae) is reinstated in the faunal list of Prince Edward Island. According to this study and literature 84 species of Hydradephaga are currently known from Prince Edward Island. The Nearctic component of the fauna is made up of 68 species (80.9%) and the Holarctic component of 16 species (19.1%). Most species are characteristic of the Boreal and Atlantic Maritime Ecozones and have a transcontinental distribution. In an examination of the Hydradephaga of insular portions of Atlantic Canada, we found that despite significantly different land areas and different distances to the neighbouring continental mainland the island faunas of Prince Edward Island and insular Newfoundland are very similar in the number of species (84 and 94 species respectively) despite differences in composition. With a land area significantly larger than that of Prince Edward Island, however, the fauna of Cape Breton Island was 39% smaller consisting of 53 species. This difference could be due to the comparative lack of collecting efforts on Cape Breton Island.

  17. 33 CFR 110.70a - Northeast River, North East, Md.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Northeast River, North East, Md. 110.70a Section 110.70a Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.70a Northeast River, North East, Md. The water...

  18. Pengaruh Brand Ambassador Terhadap Minat Beli Konsumen MD Clinic By Lazeta

    Directory of Open Access Journals (Sweden)

    Nurvita Septya Ningrum

    2016-10-01

    Full Text Available This research at MD Clinic by Lazeta which is in the beauty services that offer health care and facial, under of PT. Medina Global Care. MD Cilinic by Lazeta use the brand ambassador of introducing their products. The selection of brand ambassador motivated by positive image brought by the celebrities. Brand ambassadors chosen by the company as a symbol or a marker to represent the wishes and needs of prospective customers. MD Clinic by Lazeta choose Syahnaz as a brand ambassador for their products which is expected to to represent the product of MD Clinic by Lazeta, so the message can be understood by the consumer, who eventually would to lead the purchase intention. The purpose of this research was to investigate the influence of brand ambassadors on consumer purchase intention MD Clinic by Lazeta, Study on Business Administration Students year in 2103 Telkom University. Researchers used quantitative research methods. This research is population research, because all population is being respondent in this research. Populations of this research are 137 respondents. Collecting data in this research is conducted by using questionnaire distributed to all respondents, which all Students on Business Administration Telkom University who knows the MD Clinic by Lazeta. Data were analyzed using simple regression analysis and descriptive analysis.The results showed that the Brand Ambassador impact of consumer purchase intention on MD Clinic by Lazeta at the Students on Business Administration Telkom University years in 2013. Based on the calculation of the coefficient of determination (R2 can be seen the influence of brand ambassador variable (X on purchase intention (Y is 42.9%. While the remaining 57.1% is influenced by other factors which not examined in this research such as, pricing, marketing strategy and others.

  19. 77 FR 29692 - Segun M. Rasaki, M.D.; Decision and Order

    Science.gov (United States)

    2012-05-18

    ... CFR 1316.67. Dated: May 4, 2012. Michele M. Leonhart, Administrator. Paul E. Soeffing, Esq., for the... reinstatement.'' Stuart A. Bergman, M.D., 70 Fed. Reg. 33,193 (DEA 2005); Roger A. Rodriguez, M.D., 70 Fed. Reg...

  20. 77 FR 35021 - Kwan Bo Jin, M.D.; Decision and Order

    Science.gov (United States)

    2012-06-12

    ...] DEA registration is not appropriate.'' Anibal P. Herrera, M.D., 61 FR 65,075, 65,078 (DEA 1996); see... ``there were serious questions as to the integrity of the registrant.'' Anibal P. Herrera, M.D., 61 FR 65...

  1. Molecular Cloning and Expression Analysis of a Hexokinase Gene, MdHXK1 in Apple

    Directory of Open Access Journals (Sweden)

    Jin Zhao

    2016-03-01

    Full Text Available A hexokinase gene named MdHXK1 (MDP0000309677 was cloned from ‘Gala’ apple (Malus × domestica Borkh.. Sequence analysis showed that the MdHXK1 gene was 1 497 bp long and encoded 499 amino acids. The predicted molecular mass of this protein was 54.05 kD, and the pI was 5.76. A phylogenetic tree indicated apple MdHXK1 exhibited the highest sequence similarity to Pyrus bretschneideri PbHXK1. Analysis of the functional domain showed that the MdHXK1 protein included two conserved kinase domains. The prediction of subcellular localization suggested that the MdHXK1 protein was mainly localized in the cytoplasm. There was an indication that MdHXK1 existed as one copy in the apple genome by Southern blotting. Silico analysis suggested that the promoter sequence contained several typical cis-acting elements, including defense, sugar signaling and phytohormone responsive elements. Quantitative real-time PCR analysis demonstrated that the MdHXK1 gene was mainly expressed in stem and flower tissues. During the development of apple fruits, the expression of the MdHXK1 gene initially increased and then decreased. The changes on Glc phosphorylation relative activity and glucose concentration showed the same trend. In addition, the expression of this gene was induced by salt stress, low temperature, and abscisic acid (ABA. Finally, we obtained and purified the fused MdHXK1 protein by recombinant prokaryotic expression. Studies have demonstrated that MdHXK1 may participate in sugar metabolism in apple fruits. Enzyme encoded by MdHXK1 is a key factor in the mediation of sugar accumulation. Recently, researchers on hexokinase at home and abroad mainly focused on model plants, such as Arabidopsis, tobacco and rice, but orchard fruit like apple were underresearched. Our research established the foundation for the further study of the functions of MdHXK1.

  2. A pilot study of MD (psychiatry) theses-based research.

    Science.gov (United States)

    Srivastava, Shrikant; Agarwal, Vivek; Subramanyam, Alka; Srivastava, Mona; Sathyanarayana Rao, T S; Rao, G Prasad; Khurana, Hitesh; Singh, Archana

    2018-01-01

    Undertaking a research project is mandatory for MD Psychiatry trainees. The present study was undertaken to assess the type of research activity being undertaken as part of MD Psychiatry dissertation, and its contribution to national and international literature. Three medical colleges supplied the data about the topic, names of the supervisor and the candidate, collaboration, funding accrued, and publication details of MD-based research carried out between years 2000 and 2010 inclusive; 95 records were collected for the final analysis. The details of the publications provided were cross-checked on the internet, which would have taken care of missed publications as well. Most studies were single-point assessment clinical studies. Only 2 studies had been funded, 11 had collaboration with other departments within the same institute, and 5 had inter-institute collaborations. Majority of the studies were not published. Only 30 were published as full paper and 9 as abstracts. Of these 30 full publications, only 3 were published in journals having JCI impact factor values (1.4, 1.3, and 1.4, respectively). The main finding of this pilot study was that MD-based research has low contribution to the national and international literature, and those articles which are published are in low impact journals. Suggestions for modifying this state of affairs are discussed.

  3. MD 2485: Active halo control using narrowband and colored noise excitations

    CERN Document Server

    Garcia Morales, Hector; Kotzian, Gerd; Maclean, Ewen Hamish; Redaelli, Stefano; Valuch, Daniel; Wagner, Joschka; CERN. Geneva. ATS Department

    2018-01-01

    This MD note summarizes the actions carried out during the MD 2485 on Active halo control using narrowband and colored noise excitations. The goal of the MD was to repeat some promising cases already tested in the past and introduce a new excitation type based on applying a colored noise. Although we were able to repeat some cases using a narrowband excitation, due to a problem with the waveform generator, the colored noise excitation could not be accomplished as expected. In any case, we provide some results that may be useful for future MDs.

  4. GENDER AND THE MBA: Differences in Career Trajectories, Institutional Support, and Outcomes.

    Science.gov (United States)

    Patterson, Sarah E; Damaske, Sarah; Sheroff, Christen

    2017-06-01

    This study asks how men's and women's careers diverge following MBA graduation from an elite university, using qualitative interview data from 74 respondents. We discover men and women follow three career pathways post-graduation: lockstep (stable employment), transitory (3 or more employers), and exit (left workforce). While similar proportions of men and women followed the lockstep pathways and launched accelerated careers, sizable gender differences emerged on the transitory pathway; men's careers soared as women's faltered on this path-the modal category for both. On the transitory path, men fared much better than women when moving to new organizations, suggesting that gender may become more salient when people have a shorter work history with a company. Our findings suggest that clear building blocks to promotions reduce gender bias and ambiguity in the promotion process, but multiple external moves hamper women, putting them at a clear disadvantage to men whose forward progress is less likely to be stalled by such moves.

  5. Experiencia inicial con la prótesis de despliegue rápido en posición aórtica Edwards Intuity

    Directory of Open Access Journals (Sweden)

    José M. Arribas

    2016-03-01

    Conclusiones: El implante de la válvula Edwards Intuity para el tratamiento de la estenosis aórtica ha sido factible, seguro y eficaz. Los tiempos de isquemia miocárdica y de circulación extracorpórea parecen reducirse en comparación con la cirugía valvular aórtica habitual. El comportamiento hemodinámico inicial de la prótesis Edwards Intuity es excelente.

  6. Rhodotorula taiwanensis MD1149 produces hypoacetylated PEFA compounds with increased surface activity compared to Rhodotorula babjevae MD1169

    Science.gov (United States)

    Rubinfeld, Bonnee; Leif, Roald; Mulcahy, Heather; Dugan, Lawrence; Souza, Brian

    2018-01-01

    Biosurfactants have several desirable characteristics in the industrial sector: detergency, antimicrobial effects, skin hydration, and emulsibility. Several yeast glycolipids are currently being utilized in these capacities: sophorolipids, ustilagic acid, and mannosylerythritol lipids (MELs). An emerging class of glycolipids, termed polyol esters of fatty acids (PEFA), have recently been reported for Rhodotorula babjevae, a basidiomycetous yeast species that secretes hyperacetylated congeners of PEFA (typically with 3–6 acetylation modifications). While screening Rhodotorula species for surfactant production, we identified a new environmental isolate identified as Rhodotorula taiwanensis MD1149 that dropped the surface tension of the liquid medium, indicating that it produced a potent biosurfactant. Acid depolymerization of the purified biosurfactants, followed by gas chromatography-mass spectrometry (GC-MS) analysis revealed that the biosurfactants were composed of PEFA compounds composed mainly of mannitol and arabitol esters of 3-hydroxy fatty acid, 3-methoxy fatty acid, and fatty acids with a single double bond; chain lengths were mainly C16 and C18. Liquid chromatography-mass spectrometry (LC-MS) confirmed the predicted accurate mass of these compounds. Interestingly, PEFA compounds produced by Rhodotorula taiwanensis MD1149 were more surface active due to their hypoacetylation profile (0–4 acetylation modifications) compared to Rhodotorula babjevae MD1169. These disparate surface active properties, based on acetylation, change the hydrophilic-lipophilic balance (HLB) of these compounds, and their potential utility within industrial applications. PMID:29293588

  7. Rhodotorula taiwanensis MD1149 produces hypoacetylated PEFA compounds with increased surface activity compared to Rhodotorula babjevae MD1169.

    Science.gov (United States)

    Lyman, Mathew; Rubinfeld, Bonnee; Leif, Roald; Mulcahy, Heather; Dugan, Lawrence; Souza, Brian

    2018-01-01

    Biosurfactants have several desirable characteristics in the industrial sector: detergency, antimicrobial effects, skin hydration, and emulsibility. Several yeast glycolipids are currently being utilized in these capacities: sophorolipids, ustilagic acid, and mannosylerythritol lipids (MELs). An emerging class of glycolipids, termed polyol esters of fatty acids (PEFA), have recently been reported for Rhodotorula babjevae, a basidiomycetous yeast species that secretes hyperacetylated congeners of PEFA (typically with 3-6 acetylation modifications). While screening Rhodotorula species for surfactant production, we identified a new environmental isolate identified as Rhodotorula taiwanensis MD1149 that dropped the surface tension of the liquid medium, indicating that it produced a potent biosurfactant. Acid depolymerization of the purified biosurfactants, followed by gas chromatography-mass spectrometry (GC-MS) analysis revealed that the biosurfactants were composed of PEFA compounds composed mainly of mannitol and arabitol esters of 3-hydroxy fatty acid, 3-methoxy fatty acid, and fatty acids with a single double bond; chain lengths were mainly C16 and C18. Liquid chromatography-mass spectrometry (LC-MS) confirmed the predicted accurate mass of these compounds. Interestingly, PEFA compounds produced by Rhodotorula taiwanensis MD1149 were more surface active due to their hypoacetylation profile (0-4 acetylation modifications) compared to Rhodotorula babjevae MD1169. These disparate surface active properties, based on acetylation, change the hydrophilic-lipophilic balance (HLB) of these compounds, and their potential utility within industrial applications.

  8. Fundraising Strategies Developed by MBA students in Project-Based Learning Courses

    Directory of Open Access Journals (Sweden)

    Joao Alberto Arantes do Amaral

    2016-12-01

    Full Text Available The ability to raise funds is a skill that most modern project managers need. While a good deal of literature exists on the strategies NGOs employ to raise funds for their operations, less attention has been paid to the strategies used by students involved in Project-Based Learning courses that often partner with NGOs. Fundraising is an important skill that not only provides students with opportunities for creativity, but also helps them develop the communication skills they will need in the work they do after they graduate.In this paper, we discuss the fundraising strategies developed by MBA students in 204 social projects completed between 2002 and 2014. The projects were done in partnership with 39 community partners in Sao Paulo, Brazil (NGOs and Public Institutions. In our study, we followed quantitative and qualitative research methods, analyzing data and documents from the projects’ databases. We identified six different fundraising strategies: organizing raffles, soliciting donations from private corporations, organizing paying events, utilizing online social networks developing crowdfunding, and soliciting individual donations.

  9. Characterization of A Am/MBA hydrogels prepared by radiation induced polymerization

    International Nuclear Information System (INIS)

    Mahmudi, N.; Rendevski, S.

    2012-01-01

    In this research the network structure of polyacrylamide hydrogels prepared by gamma radiation-induced polymerization has been investigated. The average molecular weight between cross-link junctions ‾M c and effective cross-link density of hydrogels were calculated from swelling data as well as shear modulus data. The mechanical tests showed that by increasing the amount of the cross linker methylenebisacrylamide (MBA) into hydrogels, the value of shear modulus G and cross-link density ν e increased, but the average molecular weight between cross-link junctions ‾M c , decreased. The ‾M c and the effective cross-link density ν e obtained from the mechanical characterization were significantly different than the values obtained from swelling experiments. These differences were attributed to the uncertainty on the value of the χ parameter used in the Flory-Rehner equations. The results have shown that simple compression analyses can be used for the determination of ν e without any need of polymer-solvent interaction parameter for its calculations from the swelling analysis. (Author)

  10. Transapical aortic valve implantation in Rouen: four years' experience with the Edwards transcatheter prosthesis.

    Science.gov (United States)

    Litzler, Pierre-Yves; Borz, Bogdan; Smail, Hassiba; Baste, Jean-Marc; Nafeh-Bizet, Catherine; Gay, Arnaud; Tron, Christophe; Godin, Matthieu; Caudron, Jerome; Hauville, Camille; Dacher, Jean-Nicolas; Cribier, Alain; Eltchaninoff, Hélène; Bessou, Jean-Paul

    2012-03-01

    The first French transapical transcatheter aortic valve implantation (TAVI) was performed in July 2007 in our department. To report 4-year outcomes of transapical implantation with the Edwards transcatheter bioprosthesis. We prospectively evaluated consecutive patients who underwent transapical implantation with an Edwards transcatheter bioprosthesis between July 2007 and October 2011. Patients were not suitable for conventional surgery (due to severe comorbidities) or transfemoral implantation (due to poor femoral access). Among 61 patients (59.0% men), mean logistic EuroSCORE was 27.5 ± 14.9% and mean age was 81.0 ± 6.8 years. Successful valve implantation was achieved in 59/61 patients (96.7%) of patients. The other two patients required conversion to conventional surgery due to prosthesis embolization and died. Six additional patients died in the postoperative period. Causes of perioperative death were two septic shocks (one of peritonitis), two multi-organ failure, one ventricular fibrillation and one respiratory insufficiency. Intraprocedural stroke was not observed in any patient. The actuarial survival rates at 1, 2 and 4 years were 73.8%, 67.2% and 41.0%. During this 4-year period, four patients died of cardiovascular events, but no impairment of transprosthesis gradient was observed. Our series of 61 patients who underwent transapical implantation of the Edwards transcatheter bioprosthesis shows satisfactory results, similar to other reports, considering the high level of severity of patients referred for this method. Transapical access is a reliable alternative method for patients that cannot benefit from a transfemoral approach. Copyright © 2012. Published by Elsevier Masson SAS.

  11. Edward Henry Sieveking and the demise of essential epilepsy.

    Science.gov (United States)

    Bladin, Peter F

    2008-04-01

    Edward Henry Sieveking, eminent London physician of Victorian times, is best known as the speaker at the historic meeting at which the chairman, Sir Charles Locock, seem to overshadow him in announcing the introduction of bromide--the first effective anti-convulsant. But in fact Sieveking had announced a most important conceptual advance in epileptology--the demise of "essential epilepsy". In addition his book, published soon after and based upon his lecture, is an important historical resumé of Victorian era concepts and management of epilepsy. His important contributions to the understanding and management of this condition are discussed herein.

  12. 78 FR 47412 - Tyson D. Quy, M.D.; Decision and Order

    Science.gov (United States)

    2013-08-05

    ... Green, Jr., M.D., 59 FR 51,453 (DEA 1994); David E. Trawick, D.D.S., 53 FR 5,326 (DEA 1988). Here, the...) (ten years); Norman Alpert, M.D., 58 FR 67,420, 67,421 (DEA 1993) (seven years). Here, the conditions...

  13. Diatom communities from the sub-Antarctic Prince Edward Islands: diversity and distribution patterns

    NARCIS (Netherlands)

    Van de Vijver, B.; Gremmen, N.J.M.; Smith, V.

    2008-01-01

    During an extensive survey of the freshwater and moss-inhabiting diatoms of the Prince Edward Islands, a total of 214 taxa belonging to 60 genera were found. Three main communities can be found on the two islands. A large part of the samples was grouped into an aquatic group, bringing together all

  14. Avulsion Fracture: How Is It Treated?

    Science.gov (United States)

    ... way to treat an avulsion fracture in a young athlete? Answers from Edward R. Laskowski, M.D. ... Clinic does not endorse any of the third party products and services advertised. Advertising and sponsorship policy ...

  15. Edward A. Delgado-Romero: Award for Distinguished Early Career Contributions to Psychology in the Public Interest.

    Science.gov (United States)

    2011-11-01

    Presents Edward A. Delgado-Romero, the 2011 winner of the American Psychological Association Award for Distinguished Early Career Contributions to Psychology in the Public Interest. "Societies, professions, and individual citizens are enriched by the contributions of those who care. Edward A. Delgado-Romero has demonstrated through his scholarship, leadership in psychological associations such as the National Latina/Latino Psychological Association, and collaborations with universities and school districts in Georgia that he cares and is committed to addressing challenges in the provision of culturally sensitive psychological services to benefit the public interest. His example of servant leadership leaves a legacy to other early career professionals and graduate students alike. Es un hijo honorado." (PsycINFO Database Record (c) 2011 APA, all rights reserved). 2011 APA, all rights reserved

  16. Functional Characterization of the Apple RING E3 Ligase MdMIEL1 in Transgenic Arabidopsis

    Directory of Open Access Journals (Sweden)

    Jianping AN

    2017-03-01

    Full Text Available E3 ubiquitin ligases are involved in various physiological processes, and they play pivotal roles in growth and development. In this study, we identified a previously unknown gene in the apple fruit (Malus × domestica and named it MdMIEL1. The MdMIEL1 gene encoded a protein that contained a zinc-finger domain at its N-terminus and a RING-finger motif at its C-terminus. To investigate MdMIEL1 functions, we generated transgenic Arabidopsis lines expressing the MdMIEL1 gene under the control of the Cauliflower mosaic virus 35S promoter. Interestingly, ectopic expression of MdMIEL1 in Arabidopsis produced multiple phenotypes, including early germination, early flowering and a lateral root number increase relative to wild-type plants. Further analysis indicated that MdMIEL1 regulated lateral root initiation by increasing auxin accumulation in the roots. In a word, these results suggest that, MdMIEL1 as a novel RING-finger ubiquitin ligase influences plant growth and development, and highlight that MdMIEL1 regulates lateral root growth.

  17. BayesMD: flexible biological modeling for motif discovery

    DEFF Research Database (Denmark)

    Tang, Man-Hung Eric; Krogh, Anders; Winther, Ole

    2008-01-01

    We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fashion. A mixture of Dirichlets is used as prior over nucleotide probabilities in binding sites. It is trained on trans......We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fashion. A mixture of Dirichlets is used as prior over nucleotide probabilities in binding sites. It is trained...

  18. Cultural Imperialism of the West in the Work of Edward W. Said

    Directory of Open Access Journals (Sweden)

    Ranka Jeknić

    2006-09-01

    Full Text Available This article presents the main ideas and views of Edward W. Said on the relationship between culture and imperialism, and also on the link between Western culture and the formation of imperialism. Hence, special attention is given to Said’s interpretation of novels as constructions of the geopolitical reality: i.e. the characteristics of “imperialism” are examined as found in such English and French writers as Jane Austen, Rudyard Kipling, Joseph Conrad and Albert Camus, illustrating the way how novels as an aesthetic form participated in the “cultural construction” of colonialism. In the next part of the discussion, the paper presents another main topic of Edward Said that reveals how “cultural imperialism”, “orientalism” and “covering Islam” are still, unfortunately, current topics. Special attention is given to Said's demystification of the opposition between “us” and “them”, or “the West” and “Others”, through the example of the relationship between “the West” and “Islam”. Behind this issue, unequal power relations exist, as well as unequal relations of power and knowledge; “anti-systemic movements”, especially, and the “post-colonial discourse”, in general, warns us of this.

  19. Edward Albee’s The Zoo Story: Echo/es of Contemporary Subversive Culture

    Directory of Open Access Journals (Sweden)

    Naqibun Nabi

    2016-02-01

    Full Text Available The post-world war II American social and cultural setting was ambiguously featured with enforced conformity in the name of prosperity and Americanization of the nation. Despite of this fact, American writers, especially, dramatists conveyed their message against this fixation through variety and intellectuality. Edward Albee’s The Zoo Story is one of those literary assets which dedicatedly cut through the illusions of contemporary American social and cultural ethos. Here, his characters are seen struggling constantly with their insecurities and existential angst in the society. He presents America, the so-called ‘Land of Free and Home of Braves’ (note 1, in such a portrayal that unveils the traps of cages and confinement underneath. The target of this paper is to trace Edward Albee’s heightened awareness about the post-war American socio-cultural reality evident in The Zoo Story. It also looks for the voice in which the text echoes out the anti-communist, materialistic, gender-coded boundaries, coupled with paradoxical media representations, religious bordering and how Albee challenges these issues with an anti-establishment tone. Keywords: subversive culture, anti-communism, media, religion and homosexuality

  20. Crystal twinning of human MD-2 recognizing endotoxin cores of lipopolysaccharide

    International Nuclear Information System (INIS)

    Ohto, Umeharu; Satow, Yoshinori

    2008-01-01

    Twinned crystals of humaan MD-2 are transformed into single crystals with cryoprotectant optimization. Twinning of crystals causes overlapping of two or more reciprocal lattice points, and hence structure amplitudes for a single crystalline domain are hardly obtained from X-ray diffraction intensities. MD-2 protein forms a stable complex with Toll-like receptor 4 and recognizes bacterial lipopolysaccharide (LPS). Excessive immune responses activated by LPS cause septic shocks. Saccharide-trimmed human MD-2 crystallizes in the tetragonal form with apparent Laue symmetry of 4/mmm, and diffraction intensities from these crystals indicate crystal twinning. The crystal consists of two different domains, A and B. The c A axis of domain A coincides with the c B axis of domain B with a smaller lattice, and the a A axis corresponds to the (a B + b B ) axis. This twinning severely imposes difficulty in structure determination. Through optimization of cryoprotectant, domain A was thoroughly transformed into domain B. The crystal containing only domain B is in space group P4 1 2 1 2 with one MD-2 molecule in the asymmetric unit. The structure of this form of MD-2 as well as its complex with antiendotoxic lipid IVa was successfully determined using the multiple isomorphous replacement method

  1. MD on UFOs at MKIs and MKQs

    CERN Document Server

    Baer, T; Bartmann, W; Bracco, C; Carlier, E; Dehning, B; Garrel, N; Goddard, B; Jackson, S; Jimenez, M; Kain, V; Mertens, V; Misiowiec, M; Nordt, A; Papotti, G; Uythoven, J; Wenninger, J; Zerlauth, M; Zamantzas, C; Zimmermann, F

    2012-01-01

    UFOs ("Unidentified Falling Objects") are expected to be one of the major known performance limitation of the LHC. In this MD, the production mechanism and the dynamics of UFOs at the injection kicker magnets (MKIs) and the tune kicker magnets (MKQs) were studied. This was done by pulsing the MKIs and MKQs on a gap in the partly filled machine. During the MD, in total 58 UFO-type beam loss patterns were observed directly after pulsing the MKIs. None were observed after pulsing the MKQs, which provides important input for possible mitigation strategies. The temporal and spatial distribution of the UFO events could be determined by using a dedicated BLM Study Buffer, the implications for the UFO dynamics are discussed.

  2. Sustainable water recovery from oily wastewater via forward osmosis-membrane distillation (FO-MD).

    Science.gov (United States)

    Zhang, Sui; Wang, Peng; Fu, Xiuzhu; Chung, Tai-Shung

    2014-04-01

    This study proposed and investigated a hybrid forward osmosis - membrane distillation (FO-MD) system for sustainable water recovery from oily wastewater by employing lab-fabricated FO and MD hollow fiber membranes. Stable oil-in-water emulsions of different concentrations with small droplet sizes (oil droplets and partial permeation of acetic acid could be achieved. Finally, an integrated FO-MD system was developed to treat the oily wastewater containing petroleum, surfactant, NaCl and acetic acid at 60 °C in the batch mode. The water flux in FO undergoes three-stage decline due to fouling and reduction in osmotic driving force, but is quite stable in MD regardless of salt concentration. Oily wastewater with relatively high salinity could be effectively recovered by the FO-MD hybrid system while maintaining large water flux, at least 90% feed water recovery could be readily attained with only trace amounts of oil and salts, and the draw solution was re-generated for the next rounds of FO-MD run. Interestingly, significant amount of acetic acid was also retained in the permeate for further reuse as a chemical additive during the production of crude oil. The work has demonstrated that not only water but also organic additives in the wastewater could be effectively recovered by FO-MD systems for reuse or other utilizations. Copyright © 2014 Elsevier Ltd. All rights reserved.

  3. Center of excellence for mobile sensor data-to-knowledge (MD2K).

    Science.gov (United States)

    Kumar, Santosh; Abowd, Gregory D; Abraham, William T; al'Absi, Mustafa; Beck, J Gayle; Chau, Duen Horng; Condie, Tyson; Conroy, David E; Ertin, Emre; Estrin, Deborah; Ganesan, Deepak; Lam, Cho; Marlin, Benjamin; Marsh, Clay B; Murphy, Susan A; Nahum-Shani, Inbal; Patrick, Kevin; Rehg, James M; Sharmin, Moushumi; Shetty, Vivek; Sim, Ida; Spring, Bonnie; Srivastava, Mani; Wetter, David W

    2015-11-01

    Mobile sensor data-to-knowledge (MD2K) was chosen as one of 11 Big Data Centers of Excellence by the National Institutes of Health, as part of its Big Data-to-Knowledge initiative. MD2K is developing innovative tools to streamline the collection, integration, management, visualization, analysis, and interpretation of health data generated by mobile and wearable sensors. The goal of the big data solutions being developed by MD2K is to reliably quantify physical, biological, behavioral, social, and environmental factors that contribute to health and disease risk. The research conducted by MD2K is targeted at improving health through early detection of adverse health events and by facilitating prevention. MD2K will make its tools, software, and training materials widely available and will also organize workshops and seminars to encourage their use by researchers and clinicians. © The Author 2015. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  4. MdHB1 down-regulation activates anthocyanin biosynthesis in the white-fleshed apple cultivar 'Granny Smith'.

    Science.gov (United States)

    Jiang, Yonghua; Liu, Cuihua; Yan, Dan; Wen, Xiaohong; Liu, Yanli; Wang, Haojie; Dai, Jieyu; Zhang, Yujie; Liu, Yanfei; Zhou, Bin; Ren, Xiaolin

    2017-02-01

    Coloration in apple (Malus×domestica) flesh is mainly caused by the accumulation of anthocyanin. Anthocyanin is biosynthesized through the flavonoid pathway and regulated by MYB, bHLH, and WD40 transcription factors (TFs). Here, we report that the HD-Zip I TF MdHB1 was also involved in the regulation of anthocyanin accumulation. MdHB1 silencing caused the accumulation of anthocyanin in 'Granny Smith' flesh, whereas its overexpression reduced the flesh content of anthocyanin in 'Ballerina' (red-fleshed apple). Moreover, flowers of transgenic tobacco (Nicotiana tabacum 'NC89') overexpressing MdHB1 showed a remarkable reduction in pigmentation. Transient promoter activation assays and yeast one-hybrid results indicated that MdHB1 indirectly inhibited expression of the anthocyanin biosynthetic genes encoding dihydroflavonol-4-reductase (DFR) and UDP-glucose:flavonoid 3-O-glycosyltransferase (UFGT). Yeast two-hybrid and bimolecular fluorescence complementation determined that MdHB1 acted as a homodimer and could interact with MYB, bHLH, and WD40 in the cytoplasm, consistent with its cytoplasmic localization by green fluorescent protein fluorescence observations. Together, these results suggest that MdHB1 constrains MdMYB10, MdbHLH3, and MdTTG1 to the cytoplasm, and then represses the transcription of MdDFR and MdUFGT indirectly. When MdHB1 is silenced, these TFs are released to activate the expression of MdDFR and MdUFGT and also anthocyanin biosynthesis, resulting in red flesh in 'Granny Smith'. © The Author 2017. Published by Oxford University Press on behalf of the Society for Experimental Biology. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  5. Edward Y. Hartshorne and the Reopening of German Universities, 1945-1946: His Personal Account.

    Science.gov (United States)

    Tent, James F.

    1997-01-01

    Characterizes U.S. Edward Y. Hartshorne as a "manager of German social recovery." An instructor at Harvard University and protege of sociologist Talcott Parsons, Hartshorne was instrumental in the post-war reopening of German universities. Discusses Hartshorne's activities in military intelligence and psychological warfare, as well as…

  6. The relationship of uranium isotopes to oxidation/reduction in the Edwards carbonate aquifer of Texas

    International Nuclear Information System (INIS)

    Cowart, J.B.

    1980-01-01

    The concentration of dissolved uranium and 234 U/ 238 U alpha activity ratio ( A.R. ) were determined in water samples from 23 locations in the Edwards carbonate aquifer of south central Texas by isotope dilution methods and alpha spectrometry. (orig./ME)

  7. The hydration enthalpies of Md3+ and Lr3+

    International Nuclear Information System (INIS)

    Bruechle, W.; Schaedel, M.; Scherer, U.W.; Kratz, J.V.

    1987-10-01

    Lawrencium (3-min 260 Lr) and lighter actinides were produced in the bombardement of a 249 Bk target with 18 O ions and loaded onto a cation exchange column in 0.05 M α-hydroxy-isobutyrate solution at pH = 4.85 together with the radioactive lanthanide tracers 166 Ho, 171 Er, and 171 Tm. In elutions with 0.12 M α-hydroxy-isobutyrate solution (pH = 4.85) trivalent Lr was eluted exactly together with the Er tracer and Md close to Ho. Lr elutes much later than expected based on the known elution positions of the lighter actinides and the expected analogy to the elution positions of the homologous lanthanides. From the measured elution positions, ionic radii were calculated for Lr 3+ and Md 3+ . Semiempirical models allow the calculation of the heat of hydration from the ionic radii, resulting in ΔH hyd ≅ - 3654 kJ/mol for Md 3+ and ΔH hyd ≅ - 3689 kJ/mol for Lr 3+ . (orig.)

  8. New records of alien vascular plants from Marion and Prince Edward Islands, sub-Antarctic

    NARCIS (Netherlands)

    Gremmen, N.J.M.; Smith, V.

    1999-01-01

    A survey was made of the distribution of introduced vascular plants on Marion and Prince Edward Islands. The results of this survey were compared to results of previous surveys (1965/66, 1975, 1981, 1989). Four new introductions to Marion Island have taken place, three of which involved species that

  9. Obituary: Edward W. Burke, Jr. (1924-2011)

    Science.gov (United States)

    Bloomer, Raymond, Jr.

    2011-12-01

    Dr. Edward W. Burke Jr. passed away on June 15, 2011, after suffering a heart attack. Dr. Burke devoted his professional life to the research and teaching of physics and astronomy at King College in Bristol, Tennessee. Edward W. Burke, Jr., was born in Macon, Georgia, on September 16, 1924. He was a Navy veteran, having been commissioned as an ensign in 1944. He served in the Pacific near the end of World War II. He proceeded to complete his undergraduate degree in mathematics from Presbyterian College in 1947 and pursued the M.S. and Ph.D. in physics (1949 and 1954, respectively) at the University of Wisconsin. Under the direction of Professor Julian Mack, his thesis was titled "Isotope Shift in the Spectra of Boron." Although he did research in atomic spectra in the early part of his career, his interest in astronomy and variable stars in particular were his primary interests during his long academic career. Dr. Burke began his illustrious career at King College in 1949. He initiated the astronomy program there in 1950, included constructing a 12.5 inch Newtonian telescope, homemade as was most everything in those days. Many of his students learned about photometry at the Burke Observatory on the college campus. Burke was known for his trips to the Kitt Peak and Lowell observatories accompanied by undergraduate students on his trips, all of which were made by automobile which he preferred over flying. His initial interest in Ap stars later broadened into variable and especially eclipsing binary stars. His motivation was maintained by his desire to have his students experience basic research and to spark their interest in advanced degrees. Numerous students achieved advanced science and medical degrees because of Burke's encouragement and mentoring. In 1959, Dr. Burke was awarded a Fulbright professorship and traveled to Chile where he taught physics for a year in the Engineering School at the University of Chile in Santiago. He worked to establish a physics

  10. 76 FR 81826 - Drawbridge Operation Regulation; Pocomoke River, Pocomoke City, MD

    Science.gov (United States)

    2011-12-29

    ... Operation Regulation; Pocomoke River, Pocomoke City, MD AGENCY: Coast Guard, DHS. ACTION: Notice of... River, mile 15.6, at Pocomoke City, MD. The deviation restricts the operation of the draw span to... five hours advance notice is given. The Route 675 Bridge across Pocomoke River, mile 15.6 at Pocomoke...

  11. The molecular mechanism underlying anthocyanin metabolism in apple using the MdMYB16 and MdbHLH33 genes.

    Science.gov (United States)

    Xu, Haifeng; Wang, Nan; Liu, Jingxuan; Qu, Changzhi; Wang, Yicheng; Jiang, Shenghui; Lu, Ninglin; Wang, Deyun; Zhang, Zongying; Chen, Xuesen

    2017-05-01

    MdMYB16 forms homodimers and directly inhibits anthocyanin synthesis via its C-terminal EAR repressor. It weakened the inhibitory effect of MdMYB16 on anthocyanin synthesis when overexpressing MdbHLH33 in callus overexpressing MdMYB16. MdMYB16 could interact with MdbHLH33. Anthocyanins are strong antioxidants that play a key role in the prevention of cardiovascular disease, cancer, and diabetes. The germplasm of Malus sieversii f. neidzwetzkyana is important for the study of anthocyanin metabolism. To date, only limited studies have examined the negative regulatory mechanisms underlying anthocyanin synthesis in apple. Here, we analyzed the relationship between anthocyanin levels and MdMYB16 expression in mature Red Crisp 1-5 apple (M. domestica) fruit, generated an evolutionary tree, and identified an EAR suppression sequence and a bHLH binding motif of the MdMYB16 protein using protein sequence analyses. Overexpression of MdMYB16 or MdMYB16 without bHLH binding sequence (LBSMdMYB16) in red-fleshed callus inhibited MdUFGT and MdANS expression and anthocyanin synthesis. However, overexpression of MdMYB16 without the EAR sequence (LESMdMYB16) in red-fleshed callus had no inhibitory effect on anthocyanin. The yeast one-hybrid assay showed that MdMYB16 and LESMdMYB16 interacted the promoters of MdANS and MdUFGT, respectively. Yeast two-hybrid, pull-down, and bimolecular fluorescence complementation assays showed that MdMYB16 formed homodimers and interacted with MdbHLH33, however, the LBSMdMYB16 could not interact with MdbHLH33. We overexpressed MdbHLH33 in callus overexpressing MdMYB16 and found that it weakened the inhibitory effect of MdMYB16 on anthocyanin synthesis. Together, these results suggested that MdMYB16 and MdbHLH33 may be important part of the regulatory network controlling the anthocyanin biosynthetic pathway.

  12. Cultural Pragmatics in Edward Albee’s The Zoo Story

    Directory of Open Access Journals (Sweden)

    Dodhy S.

    2016-01-01

    Full Text Available This article engages debates on how changing cultural values impinge on the behavioral patterns of an individual by considering social actions as distinctly mobile engagement with the environment. Cultural Pragmatics is essential for a close examination of Edward Albee’s The Zoo Story. This article attempts to investigate how intentions of interactants are culture driven and culture related. People are led to a state of disorientation due to collapse of cultural values and discontinuity of conventional view points and beliefs. The speaker’s discourse highlights the character’s inability to communicate to suggest the emptiness of hackneyed social intercourse resulting in psychopathological diseases among individuals.

  13. PuReMD-GPU: A reactive molecular dynamics simulation package for GPUs

    International Nuclear Information System (INIS)

    Kylasa, S.B.; Aktulga, H.M.; Grama, A.Y.

    2014-01-01

    We present an efficient and highly accurate GP-GPU implementation of our community code, PuReMD, for reactive molecular dynamics simulations using the ReaxFF force field. PuReMD and its incorporation into LAMMPS (Reax/C) is used by a large number of research groups worldwide for simulating diverse systems ranging from biomembranes to explosives (RDX) at atomistic level of detail. The sub-femtosecond time-steps associated with ReaxFF strongly motivate significant improvements to per-timestep simulation time through effective use of GPUs. This paper presents, in detail, the design and implementation of PuReMD-GPU, which enables ReaxFF simulations on GPUs, as well as various performance optimization techniques we developed to obtain high performance on state-of-the-art hardware. Comprehensive experiments on model systems (bulk water and amorphous silica) are presented to quantify the performance improvements achieved by PuReMD-GPU and to verify its accuracy. In particular, our experiments show up to 16× improvement in runtime compared to our highly optimized CPU-only single-core ReaxFF implementation. PuReMD-GPU is a unique production code, and is currently available on request from the authors

  14. PuReMD-GPU: A reactive molecular dynamics simulation package for GPUs

    Energy Technology Data Exchange (ETDEWEB)

    Kylasa, S.B., E-mail: skylasa@purdue.edu [Department of Elec. and Comp. Eng., Purdue University, West Lafayette, IN 47907 (United States); Aktulga, H.M., E-mail: hmaktulga@lbl.gov [Lawrence Berkeley National Laboratory, 1 Cyclotron Rd, MS 50F-1650, Berkeley, CA 94720 (United States); Grama, A.Y., E-mail: ayg@cs.purdue.edu [Department of Computer Science, Purdue University, West Lafayette, IN 47907 (United States)

    2014-09-01

    We present an efficient and highly accurate GP-GPU implementation of our community code, PuReMD, for reactive molecular dynamics simulations using the ReaxFF force field. PuReMD and its incorporation into LAMMPS (Reax/C) is used by a large number of research groups worldwide for simulating diverse systems ranging from biomembranes to explosives (RDX) at atomistic level of detail. The sub-femtosecond time-steps associated with ReaxFF strongly motivate significant improvements to per-timestep simulation time through effective use of GPUs. This paper presents, in detail, the design and implementation of PuReMD-GPU, which enables ReaxFF simulations on GPUs, as well as various performance optimization techniques we developed to obtain high performance on state-of-the-art hardware. Comprehensive experiments on model systems (bulk water and amorphous silica) are presented to quantify the performance improvements achieved by PuReMD-GPU and to verify its accuracy. In particular, our experiments show up to 16× improvement in runtime compared to our highly optimized CPU-only single-core ReaxFF implementation. PuReMD-GPU is a unique production code, and is currently available on request from the authors.

  15. Biometria de una población de Homalaspis plana (Milne Edwards, 1834 en Punta Maule (Coronel, Chile

    Directory of Open Access Journals (Sweden)

    Marco A Retamal

    1980-12-01

    Full Text Available This work deals with the bionomy of the population of Homalaspis plana (Milne Edwards, 1834 sampled in Coronel, Chile. Homalaspis plana share his biotope with: Paraxanthus barbiger (Poeppig, 1836 and Gaudichaudia gaudichaudi (Milne Edwards, 1834. A marked sexual dimorphism is apparent, the males are larger and heavier than the females; moreover, the volumes of the chelae of the first are also larger. The percentaje of the female population was significantly larger than the males population. The spawning extends from June to December. Each class of the ovigerous females, gives a different contribution, the maxima is done by the 5,74 cm class with 29,21%. The minimum size of ovigerous females is 49,3 mm L.C

  16. A social desirability scale for the MMPI-2. Which of the two: Wiggins (WSD or Edwards (ESD?

    Directory of Open Access Journals (Sweden)

    Cristina Tobon

    2009-07-01

    Full Text Available The objective of this research aims to comparatively analyze the diagnostic accuracy of two social desirability detection scales that have been obtained from the 567 items that comprise the Minnesota Multiphasic Personality Inventory-2 (MMPI-2: Wiggins Wsd Scale and Edwards ESD Scale. The 583 participants (232 men and 351 women were differentiated into two groups according to their way of answering: Honest response group (N = 310 who replied truthfully following the guidelines of MMPI-2, and simulated response group (N = 273 who were instructed to intentionally and consistently show a positive image of themselves. The results have shown a higher diagnostic accuracy and predictive power, although less reliability (Cronbach's α for the Wiggins (Wsd Scale than for Edwards (ESD.

  17. MD#2183: Calibration of the IR6 B2 diamond BLMs

    CERN Document Server

    Valette, Matthieu; Lindstrom, Bjorn Hans Filip

    2018-01-01

    In case of an asynchronous beam dump with a fully filled LHC machine, causing ~40 bunches to impact on the movable dump protection absorber (TCDQ), it is expected that all standard ionisation chamber Beam Loss Monitors (IC BLM) around the LHC dumping region in IR6 will be saturated. Diamond Beam Loss Monitors (dBLM) were therefore installed next to the TCDQ downstream of the extraction kickers. These detectors allow resolving losses at a nanosecond timescale and with a dynamic range of several orders of magnitude; thus, allowing to derive the number of nominal bunches impacting the TCDQ. After a first series of calibrations using asynchronous beam dump tests, an experiment was conducted during MD#1182 to demonstrate the possibility of resolving a nominal bunch hitting the TCDQ. During this first MD only the Beam 1 dBLM was calibrated appropriately, a second calibration MD was therefore performed in 2017 for the B2 system. Results from this MD and conclusions regarding dBLM saturation with a top energy nominal...

  18. Bibliography of seabirds in the waters of Southern Africa, the Prince Edward and Tristan groups

    CSIR Research Space (South Africa)

    Cooper, J

    1981-12-01

    Full Text Available The titles of 2 088 publications are given which refer to seabirds in the waters of southern Africa, the Prince Edward Islands, the Tristan da Cunha group and Gough Island. An index lists the relevant publications by number for 117 species...

  19. Neue Taxa von Lunatipula Edwards aus der mediterranen Subregion der Palaearktis (Diptera, Tipulidae, Tipula Linnaeus)

    NARCIS (Netherlands)

    Theischinger, Günther

    1979-01-01

    Eight new species and three new subspecies of Lunatipula Edwards are described and their affinities are discussed. The new taxa are: Tipula (Lunatipula) rocina from Spain, T. (L.) antichasia, T. (L.) hera, T. (L.) klytaimnestra, T. (L.) pythia. T. (L.) caudispina parnonensis, T. (L.) penelope

  20. Tendinitis Pain: Should I Apply Ice or Heat?

    Science.gov (United States)

    ... is better for relieving tendinitis pain — ice or heat? Answers from Edward R. Laskowski, M.D. When you're first injured, ice is a better choice than heat — especially for about the first three days or ...

  1. "Affection in Education": Edward Carpenter, John Addington Symonds and the Politics of Greek Love

    Science.gov (United States)

    Quinn, Josephine Crawley; Brooke, Christopher

    2011-01-01

    The paper examines Edward Carpenter's 1899 essay on education that defended the value of powerful same-sex attachments, either between older and younger boys or between teachers and pupils, in the context of Victorian ideologies of same-sex affection. Linda Dowling has described how "a homosexual counterdiscourse able to justify male love in…

  2. An Appreciation and Analysis of "Edward Burtynsky--Manufactured Landscapes": A Film by Jennifer Baichwal

    Science.gov (United States)

    Donar, Ann

    2010-01-01

    This article begins with a synopsis of the film "Edward Burtynsky: Manufactured Landscapes", directed by Jennifer Baichwal. While the author can relate to the statements made in this synopsis, her experience and understanding of this 90-minute journey is much more intense and complex. In this essay, she attempts to dissect and examine…

  3. 76 FR 53961 - Harold Edward Smith, M.D.; Revocation Of Registration

    Science.gov (United States)

    2011-08-30

    ... evidence must be ``clear, unequivocal, and convincing,'' the ``ultimate finding of materiality turns on a... instances manifests a shocking level of dishonesty on his part. 21 U.S.C. 824(a)(1). Accordingly, Respondent...

  4. Edward jenner and the small pox vaccine.

    Science.gov (United States)

    Smith, Kendall A

    2011-01-01

    Edward Jenner, who discovered that it is possible to vaccinate against Small Pox using material from Cow Pox, is rightly the man who started the science of immunology. However, over the passage of time many of the details surrounding his astounding discovery have been lost or forgotten. Also, the environment within which Jenner worked as a physician in the countryside, and the state of the art of medicine and society are difficult to appreciate today. It is important to recall that people were still being bled at the time, to relieve the presence of evil humors. Accordingly, this review details Jenner's discovery and attempts to place it in historical context. Also, the vaccine that Jenner used, which decreased the prevalence of Small Pox worldwide in his own time, and later was used to eradicate Small Pox altogether, is discussed in light of recent data.

  5. Edward Jenner and the small pox vaccine

    Directory of Open Access Journals (Sweden)

    Kendall A Smith

    2011-06-01

    Full Text Available Edward Jenner, who discovered that it is possible to vaccinate against Small Pox using material from Cow Pox, is rightly the man who started the science of immunology. However, over the passage of time many of the details surrounding his astounding discovery have been lost or forgotten. Also, the environment within which Jenner worked as a physician in the countryside, and the state of the art of medicine and society are difficult to appreciate today. It is important to recall that people were still being bled at the time, to relieve the presence of evil humors. Accordingly, this review details Jenner’s discovery and attempts to place it in historical context. Also, the vaccine that Jenner used, which decreased the prevelance of Small Pox worldwide in his own time, and later was used to eradicate Small Pox altogether, is discussed in light of recent data.

  6. Edward B. Aveling: the people's Darwin.

    Science.gov (United States)

    Paylor, Suzanne

    2005-06-01

    By the late-19th century, evolutionary theory, known by most people as Darwinism, had earned a reputation as an atheistic theory that challenged religious orthodoxy. From recent historical work we now know a great deal about how those with religious convictions received Darwinian ideas, and the role that professional scientists played in styling and communicating 'Darwinism' to the wider public and between themselves. However, relatively little is known about how Darwinian ideas were received and used by avowedly irreligious groups, and how these groups set about communicating their own version of Darwinism to a public hungry for cheap and accessible science. The activities of the Secularist Edward Bibbins Aveling, a prolific popularizer of Darwinian ideas in the late-19th century, offer a unique insight into this relatively uncharted territory. His work helped to develop the polemic of popular irreligious groups and imbue Darwinism with overtly atheistic connotations; it also engendered unprecedented support for atheism from the general public, and challenged the monopoly that some professional scientists enjoyed over imparting serious scientific knowledge to them.

  7. Neotectonic investigations in Southern Ontario. Prince Edward County - Phase 2

    International Nuclear Information System (INIS)

    McFall, G.H.; Allam, A.

    1991-06-01

    This report summarizes the preliminary results of geological and geophysical investigations and offshore side scan sonar surveys of the bedrock and unconsolidated sediments in Prince Edward County, Southern Ontario, by the Ontario Geological Survey in 1989. Investigations were focused on deformations in the bedrock and the surficial deposits. Some of these deformations may be neotectonic in origin. Low magnitude seismicity in the Prince Edward County region appears to be spatially related to a major regional fault system that crosses Lake Ontario and consists of the seismically active Clarendon-Linden Fault System in New York State, the Picton-Napanee and Rideau Faults, the Frontenac-Sharbot Lake Terrane Boundary and the assumed Salmon River Fault in Ontario. Detailed observations were made in the Long Point study area and the Mountain View and Picton Quarries. Bedrock structural features were documented, including: joints; normal, reverse and strike strip faults; brittle folds; and Jurassic age ultramafic dyke. Detailed refraction seismic surveys were conducted across a local fault and possible fold structures. Magnetic surveys, conducted in conjunction with the offshore side scan sonar surveys, documented large magnetic anomalies southeast of Point Petre and at the northeast end of Long Reach. Side scan sonar surveys of the lake bottom to the east of Point Petre confirm the presence of pop-ups in that area of the lake bottom which is immediately adjacent to where pop-ups are observed on land. The pop-ups present in the lake bottom have similar orientations to those mapped in the study area

  8. Geologic framework and hydrogeologic characteristics of the outcrops of the Edwards and Trinity aquifers, Medina Lake area, Texas

    Science.gov (United States)

    Small, Ted A.; Lambert, Rebecca B.

    1998-01-01

    The hydrogeologic subdivisions of the Edwards aquifer outcrop in the Medina Lake area in Medina and Bandera Counties generally are porous and permeable. The most porous and permeable appear to be hydrogeologic subdivision VI, the Kirschberg evaporite member of the Kainer Formation; and hydrogeologic subdivision III, the leached and collapsed members, undivided, of the Person Formation. The porosity of the rocks in the Edwards aquifer outcrop is related to depositional or diagenetic elements along specific stratigraphic horizons (fabric selective) and to dissolution and structural elements that can occur in any lithostratigraphic horizon (not fabric selective). Permeability depends on the physical properties of the rock such as size, shape, and distribution of pores.

  9. MD2036: UFO Dynamics Studies and UFO Fast Detection

    CERN Document Server

    Belanger, Philippe; Valette, Matthieu; Lindstrom, Bjorn Hans Filip; Grob, Laura Katharina; Schmidt, Rudiger; Wollmann, Daniel

    2017-01-01

    UFOs are one of the remaining unknown related to LHC operation. Therefore, improving the understanding of UFO dynamics and validating the developed models against direct beam measurements is of fundamental importance in view of LHC operation at 7 TeV and with HL-LHC beam intensities. If not understood, UFOs could also be a showstopper for future machines such as FCC. This MD demonstrates new methods to study the dynamic behaviour of a calibrated UFO, simulated by the interaction of wire scanners with the beam. The events created during the MD were monitored using diamond BLMs in IR7, providing bunch-by-bunch resolution measurements. The analysis presented herein shows that blown-up bunches can be used to identify the plane of movement of UFOs, that bunch profiles and bunch sizes can be measured with dBLMs with good precision, that simulation of expected losses are in good agreement with measurements for oscillating bunches and that the space resolution of the acquisition system used during the MD is about 10 ...

  10. The prosthetic implant of MBA Optetrak in the treatment of knee osteoarthritis: 5 years of experience.

    Science.gov (United States)

    Pedrazzini, A; Pogliacomi, F; Scaravella, E; Pompili, M; Ceccarelli, F

    2014-09-24

    In this study the authors report their experience in treating knee osteoarthritis with MBA Optetrak prosthetic implant, designed to minimize the stress of high density polyethylene. In all patients, we implanted two different Optetrak prosthesis according to the validity or not of the posterior cruciate ligament. At follow-up visit, which was performed after an average follow-up of 3.6 years, we analyzed 53 patients radiographically and clinically using the Knee Society Score (KSS). Depending on our experience, we consider mandatory to have a precise selection of the patients as well as to perform an accurate capsular and ligamentous balance during operation. Furthermore, the use of prosthesis models which are similar to the normal knee allows to obtain good and durable results.

  11. Neue Taxa von Lunatipula Edwards aus der mediterranen Subregion der Palaearktis (Diptera, Tipulidae, Tipula Linnaeus)

    NARCIS (Netherlands)

    Theischinger, Günther

    1987-01-01

    12 new species and 3 new subspecies of Lunatipula Edwards from Greece and Turkey are described or defined. The new taxa are: T. (L.) montifer tasucuensis, T. (L.) musensis, T. (L.) vermooleni, T. (L.) lyrion, Tipula (Lunatipula) paravelox, T. (L.) soosi izmirensis, T. (L.) brinki, T. (L.)

  12. The Italian Job: Giambattista Vico at the Origin of Edward Said’s Humanism

    Directory of Open Access Journals (Sweden)

    Mauro Scalercio

    2016-08-01

    Full Text Available The aim of this paper is twofold. First, it will try to clarify the importance of the Italian philosopher Giambattista Vico (1668-1744 in shaping Edward Said’s categories. Second, it will shed light on the theoretical importance of such genealogy. From the philological point of view, it is important to show how profound Said’s knowledge of Vico’s work is. Therefore, this paper will follow references to Vico within the whole of Said’s work, from late the sixties ones to the posthumous Humanism and Democratic Criticism. As far as theory is concerned, understanding Said’s use of Vico’s concepts explains why Said refers to his own work with the controversial term “humanism.” Vico, critiquing modernity from the onset, is the basis on which Said built a new critical humanism. In particular, Said uses the very essential elements of the philosophy of Vico: the importance of body as the source of humanity, the critique of modern abstractions, the idea that man knows what he makes, and the idea of the historicity of every human invention and construction.   Keywords: Edward Said; Vico; Humanism; Modernity; Historicity; Facticity.

  13. Short- and long-term need for permanent pacemaker after transcatheter implantation of the Edwards Sapien aortic valve prosthesis.

    Science.gov (United States)

    Moreno, Raúl; Calvo, Luis; Sánchez-Recalde, Angel; Galeote, Guillermo; Jiménez-Valero, Santiago; López, Teresa; Plaza, Ignacio; González-Davia, Rosa; Ramírez, Ulises; Mesa, Jose Maria; Moreno-Gomez, Isidro; López-Sendón, José-Luis

    2015-11-01

    A permanent pacemaker is frequently needed after transcatheter aortic valve implantation, but the available data are mainly on the CoreValve system. To evaluate the need for new permanent pacemaker after implantation of the Edwards Sapien device, as well as related factors. We included the first 100 patients treated with the Edwards Sapien device at our institution. Of these, 12 had a permanent pacemaker before the procedure, and thus our study population was the remaining 88 patients. A permanent pacemaker was indicated in eight patients (9.1%) during hospitalization or at 30 days. After discharge, another four patients needed a pacemaker (at 42 days and three, 18, and 30 months). Two variables were associated with the need for pacemaker during hospitalization: previous dialysis (13% vs. 1%, p=0.042) and complete right bundle branch block before the procedure (25% vs. 5%, p=0.032). More than one month after the procedure, the characteristics associated with the need for pacemaker were plasma creatinine level (2.5±1.7 vs. 1.3±0.6 mg/dl, p=0.001) and previous myocardial infarction (50% vs. 10%, p=0.013). The rate of pacemaker implantation with the Edwards Sapien device was 9.1%. Right bundle branch block and dialysis were associated with this complication.

  14. MdATG18a overexpression improves tolerance to nitrogen deficiency and regulates anthocyanin accumulation through increased autophagy in transgenic apple.

    Science.gov (United States)

    Sun, Xun; Jia, Xin; Huo, Liuqing; Che, Runmin; Gong, Xiaoqing; Wang, Ping; Ma, Fengwang

    2018-02-01

    Nitrogen (N) availability is an essential factor for plant growth. Recycling and remobilization of N have strong impacts on crop yield and quality under N deficiency. Autophagy is a critical nutrient-recycling process that facilitates remobilization under starvation. We previously showed that an important AuTophaGy (ATG) protein from apple, MdATG18a, has a positive role in drought tolerance. In this study, we explored its biological role in response to low-N. Overexpression of MdATG18a in both Arabidopsis and apple improved tolerance to N-depletion and caused a greater accumulation of anthocyanin. The increased anthocyanin concentration in transgenic apple was possibly due to up-regulating flavonoid biosynthetic and regulatory genes (MdCHI, MdCHS, MdANS, MdPAL, MdUFGT, and MdMYB1) and higher soluble sugars concentration. MdATG18a overexpression enhanced starch degradation with up-regulating amylase gene (MdAM1) and up-regulated sugar metabolism related genes (MdSS1, MdHXKs, MdFK1, and MdNINVs). Furthermore, MdATG18a functioned in nitrate uptake and assimilation by up-regulating nitrate reductase MdNIA2 and 3 high-affinity nitrate transporters MdNRT2.1/2.4/2.5. MdATG18a overexpression also elevated other important MdATG genes expression and autophagosomes formation under N-depletion, which play key contributions to above changes. Together, these results demonstrate that overexpression of MdATG18a enhances tolerance to N-deficiencies and plays positive roles in anthocyanin biosynthesis through greater autophagic activity. © 2017 John Wiley & Sons Ltd.

  15. STRATEGI PEMASARAN PUBLIC RELATIONS MD ENTERTAINMENT PADA PEMASARAN FILM HABIBIE & AINUN

    OpenAIRE

    Trisna Adi Permana; Lilis Puspitasari

    2015-01-01

    Tujuan penelitian ini adalah untuk mengetahui perencanaan, implementasi serta evaluasi dari strategi Marketing Public Relations yang ditetapkan PR MD Entertainment pada film Habibie & Ainun pada tahun 2012-2013. Metode yang dilakukan adalah metode deskriptif yang bertujuan melukiskan secara sistematis fakta atau karakteristik populasi tertentu atau bidang tertentu secara faktual dan cermat. Hasil penelitian menunjukan PR MD Entertainment telah melakukan tahapan-tahapan atau Teknik...

  16. Chemical bond properties and Mossbauer spectroscopy in (La1-xMx)2CuO4 (M=Ba, Sr)

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    By using the average band-gap model, the chemical bond properties of (La1-x Mx)2CuO4(M=Ba, Sr) were calculated . The calculated covalencies for Cu(O and La(O bond in the compounds are 0.3 and 0.03 respectively. M?ssbauer isomer shifts of 57Fe doped in La2CuO4 and 119Sn doped in La2CuO4 were calculated by using the chemical surrounding factor defined by covalency and electronic polarizability. Four valence state tin and three valence iron sites were identified in 57Fe and 119Sn doped La2CuO4.

  17. MD 2179: Scraping of off-momentum halo after injection

    CERN Document Server

    Garcia Morales, Hector; Patecki, Marcin; Wretborn, Sven Joel; CERN. Geneva. ATS Department

    2018-01-01

    In this MD, a beam scraping was performed using the momentum primary collimator in IR3 where dispersion is high. A second scraping was performed using a TCSG in IR7 where dispersion is almost negligible. In such a way, we aim to disentangle the contribution of off-momentum particles to halo population. These scrapings will provide useful information to better understand the usual off-momentum losses we see at the start of the ramp. The MD results would also be used to benchmark simulations of off-momentum beam losses in order to gain confidence in simulation models.

  18. The botanical activities of George Edward Post (1838-1909).

    Science.gov (United States)

    Musselman, Lytton John

    2006-01-01

    George Edward Post wrote the first flora of the Middle East in English. His other botanical activities are less familiar. In addition to the flora, this paper discusses his teaching, fieldwork, contribution to Bible dictionaries, relations with the Boissier Herbarium in Geneva, establishment of the herbarium, and letters. Those letters are used here for the first time. Post corresponded with botanical luminaries of his day including Autran, Baker, Balfour, Barbey, Boissier, Bornmüller, Carruthers, Denslow, Haussknecht, Hooker, Schweinfurth, Thistleton-Dyer, Torrey, and Winkler. His long-term relationship with the herbarium at Geneva is highlighted. In addition, some of the lesser understood aspects of his life including chaplaincy during the American Civil War, and missionary to Syria are discussed.

  19. InforMD: a new initiative to raise public awareness about breast density.

    Science.gov (United States)

    Hugo, Honor J; Zysk, Aneta; Dasari, Pallave; Britt, Kara; Hopper, John L; Stone, Jennifer; Thompson, Erik W; Ingman, Wendy V

    2018-01-01

    On a mammogram, breast density (also known as mammographic density) is shown as white and bright regions and is associated with reduced sensitivity in cancer detection and increased breast cancer risk. However, many Australian women are unaware of the significance of breast density as it is not routinely reported or discussed. In order to address this lack of knowledge, Australian breast cancer researchers with expertise in mammographic density formed the InforMD alliance (INformation FORum on Mammographic Density) in 2016. The alliance is working to raise awareness of breast density with the goal of improving breast cancer diagnosis and health outcomes for women. The InforMD website (www.InforMD.org.au) was launched in October 2016, coinciding with a major nationwide public awareness campaign by the alliance during breast cancer awareness month. The website contains unbiased, accurate, updated information on breast density. The website also provides summaries of major research articles in layperson language, recent news items related to breast density, links to relevant information for health professionals, events, and feature articles. Members of the public and health professionals can also subscribe for news updates. The interactive online Forum section facilitates discussion between health professionals, scientists and members of the public. To increase online traffic to the website, Facebook (www.facebook.com/BeInforMD) and Twitter (https://twitter.com/BeInforMD_) pages were launched in December 2016. Since its launch, InforMD has generated considerable interest. The public awareness campaign reached over 7 million Australians through a combination of newspaper, TV, radio, and online news. The website has attracted 13,058 unique visitors and 30,353 page views (data as of 19/12/2017). Breast cancer researchers have a significant role to play in disseminating information to the public on breast density. A combination of mainstream and social media, together with

  20. Novel Biophysical Marker of Aggressive Prostate Cancer Cells

    Science.gov (United States)

    2013-06-01

    756 30.33 PrEC LHSR 8.60 687 19.71 PC-3 9.31 744 48.42 TEM 4–18 8.55 683 45.00 22Rv1 7.27 581 41.00 MD.MBA.231 8.16 652 32.43 B16.f0 9.11 728 37.37 Panc ...established human cancer cell lines evaluated, PANC -1 pancreatic cancer cells and Jurkat leukemia cells, were considerably more sensitive to the FSS

  1. An apple B-box protein, MdCOL11, is involved in UV-B- and temperature-induced anthocyanin biosynthesis.

    Science.gov (United States)

    Bai, Songling; Saito, Takanori; Honda, Chikako; Hatsuyama, Yoshimichi; Ito, Akiko; Moriguchi, Takaya

    2014-11-01

    Our studies showed that an apple B-box protein, MdCOL11, the homolog of AtBBX22, is involved in UV-B- and temperature-induced anthocyanin biosynthesis in apple peel. Anthocyanin is responsible for the red pigmentation in apple peel and a R2R3 MYB gene, MdMYBA/1/10, a homolog of MdMYBA, controls its accumulation. Arabidopsis PAP1 is under the control of a series of upstream factors involved in light signal transduction and photomorphogenesis, such as ELONGATED HYPOCOTYL 5 (HY5) and B-box family (BBX) proteins. In this study, we identified and characterized the homolog of Arabidopsis BBX22 in apple, designated as MdCOL11. Overexpression of MdCOL11 in Arabidopsis enhanced the accumulation of anthocyanin. In apples, MdCOL11 was differentially expressed in all tissues, with the highest expression in petals and the lowest expression in the xylem. Transcripts of MdCOL11 noticeably accumulated at the ripening stage, concomitant with increases in the expressions of anthocyanin biosynthesis-related genes. In an in vitro treatment experiment, MdCOL11 was upregulated in an ultra-violet (UV)-B- and temperature-dependent manner, together with the inductions of anthocyanin biosynthesis-related genes and anthocyanin accumulation in apple peel. Furthermore, a dual-luciferase assay indicated that (1) MdCOL11 regulated the expression of MdMYBA and (2) MdCOL11 was a target of MdHY5. Taken together, our results suggest that MdCOL11 is involved in MdHY5-mediated signal transduction and regulates anthocyanin accumulation in apple peel, which sheds new light on anthocyanin accumulation in apples.

  2. The Use of Technology in Prince Edward Island (Canada) High Schools: Perceptions of School Leaders

    Science.gov (United States)

    Preston, Jane P; Moffatt, Lyndsay; Wiebe, Sean; McAuley, Alexander; Campbell, Barbara; Gabriel, Martha

    2015-01-01

    The purpose of this paper is to document the perceptions of school leaders regarding the technological use, skills, and attitudes of high school teachers. Using a qualitative research approach, 11 educational leaders from Prince Edward Island (Canada) were individually interviewed. Participants represented the Department of Education, principals,…

  3. Strategi Pemasaran Public Relations Md Entertainment Pada Pemasaran Film Habibie & Ainun

    OpenAIRE

    Permana, Trisna Adi; Puspitasari, Lilis

    2015-01-01

    Tujuan penelitian ini adalah untuk mengetahui perencanaan, implementasi serta evaluasi dari strategiMarketing Public Relations yang ditetapkan PR MD Entertainment pada film Habibie & Ainun pada tahun2012-2013. Metode yang dilakukan adalah metode deskriptif yang bertujuan melukiskan secara sistematisfakta atau karakteristik populasi tertentu atau bidang tertentu secara faktual dan cermat. Hasil penelitianmenunjukan PR MD Entertainment telah melakukan tahapan-tahapan atau Teknik PR pada film Ha...

  4. Cultural Imperialism of the West in the Work of Edward W. Said

    OpenAIRE

    Ranka Jeknić

    2006-01-01

    This article presents the main ideas and views of Edward W. Said on the relationship between culture and imperialism, and also on the link between Western culture and the formation of imperialism. Hence, special attention is given to Said’s interpretation of novels as constructions of the geopolitical reality: i.e. the characteristics of “imperialism” are examined as found in such English and French writers as Jane Austen, Rudyard Kipling, Joseph Conrad and Albert Camus, illustrating the way ...

  5. IMPLEMENTING EDWARD DE BONO’S APPROACHES OF STRATEGIC THINKING IN THE FIELD OF PROFESSIONAL EDUCATION

    Directory of Open Access Journals (Sweden)

    Olena Lykholat

    2017-04-01

    Full Text Available Education is always regarded as a necessary factor of social development. One of the positive means to solve urgent problems in the field of professional education is not only systematization of the information, but also the creative accumulation and assimilation of the cultural experience and, as a result, of the scientific, artistic-design, project-constructive and/or technological principles of activities. The high standards to the future teachers’ professional education are caused by the binary character of the future activities: the teacher should be both a professional and a pedagogue. The transformation of the professional education, while there are lots of global challenges in the world, leads to the activation of the creative potential of the future pedagogue at a professional educational institution. The goal of this article is to analyze systems of thinking suggested by Edward de Bono, and to attempt implementing partially these approaches into strategic thinking in the field of professional education, i.e. in the future teachers’ sewing specialization at a professional educational institution. According to the goal of the article, the whole complex of scientific approaches and methods has been used at the different theoretical and empirical levels. The systemic approach is in the core of the research, following the idea of the integrity of thinking expressed by Edward de Bono and of mechanisms which facilitate it. At the moment in our volatile world there is a clear need in new type of thinking – creative and constructive, which allows to form new ideas and ways for development. The system of such a kind of thinking was developed by Edward de Bono. According to him, the main method for the process of problem solving should be: refusal from cliché and established patters of thinking; perception of the problem with humor; continuous questioning of permissiveness; change in the way of seeking for information; creation of integral

  6. Assessing the vulnerability of public-supply wells to contamination—Edwards aquifer near San Antonio, Texas

    Science.gov (United States)

    Jagucki, Martha L.; Musgrove, MaryLynn; Lindgren, Richard J.; Fahlquist, Lynne; Eberts, Sandra M.

    2011-01-01

    This fact sheet highlights findings from the vulnerability study of a public-supply well field in San Antonio, Texas. The well field consists of six production wells that tap the Edwards aquifer. Typically, one or two wells are pumped at a time, yielding an average total of 20-21 million gallons per day. Water samples were collected from public-supply wells in the well field and from monitoring wells installed along general directions of flow to the well field. Samples from the well field contained some constituents of concern for drinking-water quality, including nitrate; the pesticide compounds atrazine, deethylatrazine, and simazine; and the volatile organic compounds tetrachloroethene (also called perchloroethene, or PCE), chloroform, bromoform, and dibromochloromethane. These constituents were detected in untreated water at concentrations much less than established drinking-water standards, where such standards exist. Overall, the study findings point to four primary factors that affect the movement and fate of contaminants and the vulnerability of the public-supply well field in San Antonio, Texas: (1) groundwater age (how long ago water entered, or recharged, the aquifer), (2) fast pathways for flow of groundwater through features formed or enlarged by dissolution of bedrock, (3) recharge characteristics of the aquifer, and (4) natural geochemical processes within the aquifer. A computer-model simulation of groundwater flow and transport was used to estimate the traveltime (or age) of water particles entering public-supply well W4 in the well field. Modeled findings show that almost half of the water reaching the public-supply well is less than 2 years old. Such a large percentage of very young water indicates that (1) contaminants entering the aquifer may be transported rapidly to the well, (2) there is limited time for chemical reactions to occur in the aquifer that may attenuate contaminants, and (3) should recharge water become contaminated with

  7. Angiotensin II induces kidney inflammatory injury and fibrosis through binding to myeloid differentiation protein-2 (MD2).

    Science.gov (United States)

    Xu, Zheng; Li, Weixin; Han, Jibo; Zou, Chunpeng; Huang, Weijian; Yu, Weihui; Shan, Xiaoou; Lum, Hazel; Li, Xiaokun; Liang, Guang

    2017-03-21

    Growing evidence indicates that angiotensin II (Ang II), a potent biologically active product of RAS, is a key regulator of renal inflammation and fibrosis. In this study, we tested the hypothesis that Ang II induces renal inflammatory injury and fibrosis through interaction with myeloid differentiation protein-2 (MD2), the accessory protein of toll-like receptor 4 (TLR4) of the immune system. Results indicated that in MD2 -/- mice, the Ang II-induced renal fibrosis, inflammation and kidney dysfunction were significantly reduced compared to control Ang II-infused wild-type mice. Similarly, in the presence of small molecule MD2 specific inhibitor L6H21 or siRNA-MD2, the Ang II-induced increases of pro-fibrotic and pro-inflammatory molecules were prevented in tubular NRK-52E cells. MD2 blockade also inhibited activation of NF-κB and ERK. Moreover, MD2 blockade prevented the Ang II-stimulated formation of the MD2/TLR4/MyD88 signaling complex, as well as the increased surface binding of Ang II in NRK-52E cells. In addition, Ang II directly bound recombinant MD2 protein, rather than TLR4 protein. We conclude that MD2 is a significant contributor in the Ang II-induced kidney inflammatory injury in chronic renal diseases. Furthermore, MD2 inhibition could be a new and important therapeutic strategy for preventing progression of chronic renal diseases.

  8. Image fusion in craniofacial virtual reality modeling based on CT and 3dMD photogrammetry.

    Science.gov (United States)

    Xin, Pengfei; Yu, Hongbo; Cheng, Huanchong; Shen, Shunyao; Shen, Steve G F

    2013-09-01

    The aim of this study was to demonstrate the feasibility of building a craniofacial virtual reality model by image fusion of 3-dimensional (3D) CT models and 3 dMD stereophotogrammetric facial surface. A CT scan and stereophotography were performed. The 3D CT models were reconstructed by Materialise Mimics software, and the stereophotogrammetric facial surface was reconstructed by 3 dMD patient software. All 3D CT models were exported as Stereo Lithography file format, and the 3 dMD model was exported as Virtual Reality Modeling Language file format. Image registration and fusion were performed in Mimics software. Genetic algorithm was used for precise image fusion alignment with minimum error. The 3D CT models and the 3 dMD stereophotogrammetric facial surface were finally merged into a single file and displayed using Deep Exploration software. Errors between the CT soft tissue model and 3 dMD facial surface were also analyzed. Virtual model based on CT-3 dMD image fusion clearly showed the photorealistic face and bone structures. Image registration errors in virtual face are mainly located in bilateral cheeks and eyeballs, and the errors are more than 1.5 mm. However, the image fusion of whole point cloud sets of CT and 3 dMD is acceptable with a minimum error that is less than 1 mm. The ease of use and high reliability of CT-3 dMD image fusion allows the 3D virtual head to be an accurate, realistic, and widespread tool, and has a great benefit to virtual face model.

  9. New species of Pseudosmittia Edwards, 1932 and new records of Allocladius Kieffer, 1913 (Diptera: Chironomidae, Orthocladiinae) from South America.

    Science.gov (United States)

    Mauad, Melina; Siri, Augusto; Donato, Mariano

    2013-01-01

    Three new species of Pseudosmittia Edwards from the Neotropical region, P. satheri, P. larga and P. trapezoidea, are described and figured as males. Allocladiusfortispinatus (Edwards), A. globosus Andersen et al. and A. quadrus Andersen et al. are redescribed on the basis of new material and their geographical distribution updated. A phylogenetic analysis was performed in order to assess the phylogenetic relationships of the new species. As a result, the species P. sœtheri and P. larga are found to be sister species belonging to the angusta group. The species P. trapezoidea is the sister group of the clade ((P. propetropis (P. tropis--P. lamellata)) and belongs to the brevifurcata group sensu lato.

  10. StandsSIM-MD: a Management Driven forest SIMulator

    Directory of Open Access Journals (Sweden)

    Susana Barreiro

    2016-07-01

    Full Text Available Aim of the study: The existing stand level forest simulators available in Portugal were not developed with the aim of including up-to-date model versions and were limited in terms of accounting for forest management. The simulators’ platform, sIMfLOR was recently created to implement different growth models with a common philosophy. The objective was developing one easily-updatable, user-friendly, forest management and climate change sensitive simulator capable of projecting growth for the main tree species in Portugal. Area of the study: Portugal. Material and methods: The new simulator was programmed in a modular form consisting of several modules. The growth module integrates different forest growth and yield models (empirical and process-based for the main wood production tree species in Portugal (eucalypt, umbrella and maritime pines; whereas the management module drives the growth projections along the planning horizon according to a range of forest management approaches and climate (at present only available for eucalypt. Main results: The main result is the StandsSIM-MD Management Driven simulator that overcomes the limitations of the existing stand level simulators. It is a step forward when compared to the models currently available in the sIMfLOR platform covering more tree species, stand structures and stand compositions. It is focused on end-users and it is based on similar concepts regarding the generation of required inputs and generated outputs. Research highlights: -          Forest Management Driven simulations approach -          Multiple Prescriptions-Per-Stand functionality -          StandsSIM-MD can be used to support landowners decisions on stand forest management -          StandsSIM-MD simulations at regional level can be combined with optimization routines Keywords: Forest simulator, Forest Management Approaches; StandsSIM-MD; forest management.

  11. High-heat-load monochromator options for the RIXS beamline at the APS with the MBA lattice

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Zunping, E-mail: zpliu@anl.gov; Gog, Thomas, E-mail: gog@aps.anl.gov; Stoupin, Stanislav A.; Upton, Mary H.; Ding, Yang; Kim, Jung-Ho; Casa, Diego M.; Said, Ayman H.; Carter, Jason A.; Navrotski, Gary [Advanced Photon Source, Argonne National Laboratory, 9700 S. Cass Ave, Lemont, IL 60439 (United States)

    2016-07-27

    With the MBA lattice for APS-Upgrade, tuning curves of 2.6 cm period undulators meet the source requirements for the RIXS beamline. The high-heat-load monochromator (HHLM) is the first optical white beam component. There are four options for the HHLM such as diamond monochromators with refrigerant of either water or liquid nitrogen (LN{sub 2}), and silicon monochromators of either direct or indirect cooling system. Their performances are evaluated at energy 11.215 keV (Ir L-III edge). The cryo-cooled diamond monochromator has similar performance as the water-cooled diamond monochromator because GaIn of the Cu-GaIn-diamond interface becomes solid. The cryo-cooled silicon monochromators perform better, not only in terms of surface slope error due to thermal deformation, but also in terms of thermal capacity.

  12. The exotic crab Percnon gibbesi (H. Milne Edwards, 1853 (Decapoda, Grapsidae in the Central Mediterranean

    Directory of Open Access Journals (Sweden)

    M. Relini

    2000-09-01

    Full Text Available The grapsid crab Percnon gibbesi (H. Milne Edwards, 1853, not previously recorded in the Mediterranean, has been found by underwater observations in several localities of Linosa, Pelagie Islands, (Italy. This presence increases the list of alien Decapods in the Mediterranean, with a form which can be considered a western migrant.

  13. An unusual dimeric structure and assembly for TLR4 regulator RP105-MD-1

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sung-il; Hong, Minsun; Wilson, Ian A [Scripps

    2011-11-16

    RP105-MD-1 modulates the TLR4-MD-2-mediated, innate immune response against bacterial lipopolysaccharide (LPS). The crystal structure of the bovine 1:1 RP105-MD-1 complex bound to a putative endogenous lipid at 2.9 Å resolution shares a similar overall architecture to its homolog TLR4-MD-2 but assembles into an unusual 2:2 homodimer that differs from any other known TLR-ligand assembly. The homodimer is assembled in a head-to-head orientation that juxtaposes the N-terminal leucine-rich repeats (LRRs) of the two RP105 chains, rather than the usual tail-to-tail configuration of C-terminal LRRs in ligand-activated TLR dimers, such as TLR1-TRL2, TLR2-TLR6, TLR3-TLR3 and TLR4-TLR4. Another unusual interaction is mediated by an RP105-specific asparagine-linked glycan, which wedges MD-1 into the co-receptor binding concavity on RP105. This unique mode of assembly represents a new paradigm for TLR complexes and suggests a molecular mechanism for regulating LPS responses.

  14. Zooplankton around Marion and Prince Edward Islands; 24 March 1976 to 25 November 1976 (NODC Accession 0000940)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Samples of zooplankton taken at 12 stations around Marion and Prince Edward Islands (47oS - 35oE) in March 1976 from the 'Marion-Dufresne' and at 2 stations in the...

  15. Department of Neurosurgery, Seth Gordhandas Sunderdas Medical College and King Edward VII Memorial (K.E.M.) Hospital, Mumbai.

    Science.gov (United States)

    Pandya, Sunil; Goel, Atul

    2017-01-01

    Seth Gordhandas Sunderdas Medical College and King Edward VII Memorial (K.E.M.) Hospital, Mumbai were inaugurated in 1925. This article traces its illustrious history and of the eminent neurosurgeons who shaped its destiny.

  16. Graduate Management Project. The Pursuit of Quality in Military Health Care: Are We Held to a Higher Standard?

    Science.gov (United States)

    2006-06-20

    end in itself, a final cause of seeking the good in other pursuits (Abelson & Nielsen, 1967). Immanuel Kant’s ideas also have a significant influence...on ethics. Kant defined ethics as the philosophical science that "... deals with the laws of free moral action" ( Kant , 1964, p. 13). Kant’s ethical...Organization, (n.d.). Biography of the Honorable William Winkenwerder, Jr., M.D., MB.A., Assistant Secretary of Defense for Health Affairs. Retrieved

  17. Branding Prince Edward County as a Gastronomic Niche Tourism Destination: A Case Study

    OpenAIRE

    Geneviève Brisson; Rocci Luppicini

    2015-01-01

    Increasingly, gastronomy is playing a role in people's motivation for travel, and destinations are making food and beverages their main attraction. This study explored the growing field of gastronomic tourism, a type of niche tourism, through the theoretical framework of destination branding theory. Using a qualitative case study research design, this research examined the branding of the emergent region of Prince Edward County, Ontario, Canada as a gastronomic niche tourism destination from ...

  18. Find an Orthopaedic Foot and Ankle MD/DO

    Science.gov (United States)

    ... All Site Content AOFAS / FootCareMD / Find a Surgeon Find a Foot & Ankle Orthopaedic Surgeon Page Content Who ... your prescribed treatment (surgical and/or non-surgical) ​ Find a Surgeon ​ Click here to find a foot ...

  19. Is the largest aqueous gold cluster a superatom complex? Electronic structure & optical response of the structurally determined Au146(p-MBA)57.

    Science.gov (United States)

    López-Lozano, Xóchitl; Plascencia-Villa, G; Calero, G; Whetten, R L; Weissker, Hans-Christian

    2017-12-07

    The new water-soluble gold cluster Au 146 (p-MBA) 57 , the structure of which has been recently determined at sub-atomic resolution by Vergara et al., is the largest aqueous gold cluster ever structurally determined and likewise the smallest cluster with a stacking fault. The core presents a twinned truncated octahedron, while additional peripheral gold atoms follow a C 2 rotational symmetry. According to the usual counting rules of the superatom complex (SAC) model, the compound attains a number of 92 SAC electrons if the overall net charge is 3- (three additional electrons). As this is the number of electrons required for a major shell closing, the question arises of whether Au 146 (p-MBA) 57 should be regarded as a superatom complex. Starting from the experimental coordinates we have analyzed the structure using density-functional theory. The optimized (relaxed) structure retains all the connectivity of the experimental coordinates, while removing much of its irregularities in interatomic distances, thereby enhancing the C 2 -symmetry feature. On analyzing the angular-momentum-projected states, we show that, despite a small gap, the electronic structure does not exhibit SAC model character. In addition, optical absorption spectra are found to be relatively smooth compared to the example of the Au 144 (SR) 60 cluster. The Au 146 (SR) 57 does not derive its stability from SAC character; it cannot be considered as a superatom complex.

  20. Molecular cloning and functional analysis of a blue light receptor gene MdCRY2 from apple (Malus domestica).

    Science.gov (United States)

    Li, Yuan-Yuan; Mao, Ke; Zhao, Cheng; Zhao, Xian-Yan; Zhang, Rui-Fen; Zhang, Hua-Lei; Shu, Huai-Rui; Hao, Yu-Jin

    2013-04-01

    MdCRY2 was isolated from apple fruit skin, and its function was analyzed in MdCRY2 transgenic Arabidopsis. The interaction between MdCRY2 and AtCOP1 was found by yeast two-hybrid and BiFC assays. Cryptochromes are blue/ultraviolet-A (UV-A) light receptors involved in regulating various aspects of plant growth and development. Investigations of the structure and functions of cryptochromes in plants have largely focused on Arabidopsis (Arabidopsis thaliana), tomato (Solanum lycopersicum), pea (Pisum sativum), and rice (Oryza sativa). However, no data on the function of CRY2 are available in woody plants. In this study, we isolated a cryptochrome gene, MdCRY2, from apple (Malus domestica). The deduced amino acid sequences of MdCRY2 contain the conserved N-terminal photolyase-related domain and the flavin adenine dinucleotide (FAD) binding domain, as well as the C-terminal DQXVP-acidic-STAES (DAS) domain. Relationship analysis indicates that MdCRY2 shows the highest similarity to the strawberry FvCRY protein. The expression of MdCRY2 is induced by blue/UV-A light, which represents a 48-h circadian rhythm. To investigate the function of MdCRY2, we overexpressed the MdCRY2 gene in a cry2 mutant and wild type (WT) Arabidopsis, assessed the phenotypes of the resulting transgenic plants, and found that MdCRY2 functions to regulate hypocotyl elongation, root growth, flower initiation, and anthocyanin accumulation. Furthermore, we examined the interaction between MdCRY2 and AtCOP1 using a yeast two-hybrid assay and a bimolecular fluorescence complementation assay. These data provide functional evidence for a role of blue/UV-A light-induced MdCRY2 in controlling photomorphogenesis in apple.

  1. James Edward Scott: The Leadership Journey of a Senior-Level African American Student Affairs Officer

    Science.gov (United States)

    Willis, Salatha T.

    2013-01-01

    The purpose of this study was to examine, understand, and describe the life, leadership, and influence of Dr. James Edward Scott on higher education and more specifically student affairs; as one of the most well-known and respected African American male chief student affairs officers in the late 20th and early 21st centuries. Using a qualitative…

  2. Fermilab's Helen Edwards receives prestigious 2003 Robert R. Wilson prize from the American Physical Society

    CERN Multimedia

    2002-01-01

    Helen Edwards has been awarded the 2003 Robert R. Wilson prize. She was cited for "her pivotal achievement and critical contribution as the leader in the design, construction, commissioning and operation of the Tevatron, and for her continued contributions to the development of high gradient superconducting linear accelerators as well as bright and intense electron sources." (1/2 page).

  3. Neue taxa von Lunatipula Edwards aus der mediterranen Subregion der Palaearktis (Diptera, Tipulidae, Tipula Linnaeus). III. Fortsetzung

    NARCIS (Netherlands)

    Theischinger, Günther

    1980-01-01

    Six new species and three new subspecies of Lunatipula Edwards are described respectively characterized. The geographical variation of some species is illustrated. The new taxa are: Tipula (Lunatipula) iberica spimila from Morocco, T. (L.) capra from Italy, T. (L.) profdrassi and T. (L.)

  4. Science and Technology Review, July-August 1998: Celebrating Edward Teller at 90

    Science.gov (United States)

    Smart, J.

    1998-07-01

    On the occasion of Edward Teller's 90th birthday, Science and Technology Review (S&TR) has the pleasure of honoring Lawrence Livermore's co-founder and most influential scientist. Teller is known for his inventive work in physics, his concepts leading to thermonuclear explosions, and his strong stands on such issues as science education, the nation's strategic defense, the needs for science in the future, and sharing scientific information. The articles in this issue also show him, as always, tirelessly moving forward with his new and changing interests.

  5. MD2725: 16L2 aperture measurement

    CERN Document Server

    Mirarchi, Daniele; Rossi, Roberto; CERN. Geneva. ATS Department

    2018-01-01

    Dumps induced by sudden increase of losses in the half-cell 16L2 have been a serious machine limitation during the 2017 run. The aim of this MD was to perform local aperture measurements in order to assess differences after the beam screen regeneration, compared to first measurements in 2017.

  6. Possibilities of production of neutron-rich Md isotopes in multi-nucleon transfer reactions

    Energy Technology Data Exchange (ETDEWEB)

    Mun, Myeong-Hwan; Lee, Young-Ouk [Korea Atomic Energy Research Institue, Daejeon (Korea, Republic of); Adamian, G.G.; Antonenko, N.V. [Joint Institute for Nuclear Research, Dubna (Russian Federation)

    2016-12-15

    The possibilities of production of yet unknown neutron-rich isotopes of Md are explored in several multi-nucleon transfer reactions with actinide targets and stable and radioactive beams. The projectile-target combinations and bombarding energies are suggested to produce new neutron-rich isotopes of Md in future experiments. (orig.)

  7. Lungworm (Crenosoma vulpis) infection in dogs on Prince Edward Island.

    Science.gov (United States)

    Bihr, T; Conboy, G A

    1999-01-01

    Crenosoma vulpis is a nematode lungworm that is highly prevalent in the red fox population of Atlantic Canada. Dogs are susceptible to infection with clinical signs consisting primarily of a chronic cough. A recent report of C. vulpis infection in 3 dogs on Prince Edward Island prompted an investigation into the importance of this parasite as a cause of chronic respiratory disease in Island dogs. A general prevalence was determined through the necropsy of dogs euthanized at the local humane society. Lungs were removed and examined for parasites using a lung flush technique. Rectal feces was collected and examined for first-stage larvae using the Baermann technique and zinc sulfate centrifugal flotation. Ten of 310 dogs (3.2%) were positive with 0-35 worms (mean = 11.0 +/- 13.4) recovered. First-stage larvae of C. vulpis were recovered in the rectal feces of the one animal in which no worms were recovered on lung flush. A second survey was conducted examining fecal samples with the Baermann technique from afebrile dogs with presenting signs of chronic cough that had no history of recent anthelmintic treatment and showed no signs of cardiac disease, based on physical examination. Fifteen of 55 dogs examined (27.3%) were definitively diagnosed as C. vulpis-positive. All of the infected dogs were treated with fenbendazole (50 mg/kg body weight, p.o. q24 h for 3-7 days). Clinical signs resolved in all of the dogs and fecal samples were negative 2-4 weeks posttreatment. It was concluded that C. vulpis infection was a significant cause of upper respiratory disease in dogs on Prince Edward Island and should be considered in all dogs with presenting signs of chronic cough. Images Figure 1. Figure 2. PMID:12001335

  8. Water at silica/liquid water interfaces investigated by DFT-MD simulations

    Science.gov (United States)

    Gaigeot, Marie-Pierre

    This talk is dedicated to probing the microscopic structural organization of water at silica/liquid water interfaces including electrolytes by first principles DFT-based molecular dynamics simulations (DFT-MD). We will present our very recent DFT-MD simulations of electrolytic (KCl, NaCl, NaI) silica/liquid water interfaces in order to unravel the intertwined structural properties of water and electrolytes at the crystalline quartz/liquid water and amorphous silica/liquid water interfaces. DFT-MD simulations provide direct knowledge of the structural organization of water and the H-Bond network formed between the water molecules within the different water layers above the silica surface. One can furthermore extract vibrational signatures of the water molecules within the interfacial layers from the DFT-MD simulations, especially non-linear SFG (Sum Frequency generation) signatures that are active at solid/liquid interfaces. The strength of the simulated spectra is that a detailed analysis of the signatures in terms of the water/water H-Bond networks formed within the interfacial water layers and in terms of the water/silica or water/electrolytes H-Bond networks can be given. Comparisons of SFG spectra between quartz/water/electrolytes and amorphous silica/water/electrolytes interfaces allow us to definitely conclude on how the structural arrangements of liquid water at these electrolytic interfaces modulate the final spectroscopic signatures. Invited speaker.

  9. The Reconciliation of W. Edwards Deming and John Dewey: An Exploration of Similarities in Motivation Theory.

    Science.gov (United States)

    Towns, William C.

    1996-01-01

    Interrogates similarities and misconceptions common to W. Edwards Deming and John Dewey, examining a reconciliation of the two within the context of motivation theory and concluding that Deming and Dewey are very similar in general outlook and the shared belief in the integrity of the individual within the social system. (SM)

  10. Oslo model, hyperuniformity, and the quenched Edwards-Wilkinson model

    Science.gov (United States)

    Grassberger, Peter; Dhar, Deepak; Mohanty, P. K.

    2016-10-01

    We present simulations of the one-dimensional Oslo rice pile model in which the critical height at each site is randomly reset after each toppling. We use the fact that the stationary state of this sand-pile model is hyperuniform to reach system of sizes >107 . Most previous simulations were seriously flawed by important finite-size corrections. We find that all critical exponents have values consistent with simple rationals: ν =4/3 for the correlation length exponent, D =9/4 for the fractal dimension of avalanche clusters, and z =10/7 for the dynamical exponent. In addition, we relate the hyperuniformity exponent to the correlation length exponent ν . Finally, we discuss the relationship with the quenched Edwards-Wilkinson model, where we find in particular that the local roughness exponent is αloc=1 .

  11. Filming Critical Female Perspectives: Edward Yang’s The Terrorizers

    Directory of Open Access Journals (Sweden)

    Kai-man Chang

    2017-04-01

    Full Text Available From his first film—a twenty-minute short, “Expectations” (1982—to his last—a three-hour masterpiece, 'Yi Yi' (2000—Edward Yang, one of the leading figures of the Taiwan New Cinema movement, devoted his career to portraying the impact of neoliberal capitalism on the lives of the citizens of Taipei. Interestingly, Yang’s films often employ female perspectives to criticize Taiwan’s education system and transnational corporations for perpetuating neoliberal capitalism’s ideology of self-fulfillment and upward mobility. This paper draws upon feminist film theory to investigate the ways in which Yang’s third feature, 'The Terrorizers' (1986, utilizes various innovative cinematic languages to engender a multitude of women’s perspectives to expose male voyeurism and ultimately criticize the impact of neoliberal capitalism in Taipei.

  12. Usefulness of multidetector-row computed tomography (MD-CT) for diagnosis and evaluation of cardiovascular anomalies in infants

    International Nuclear Information System (INIS)

    Kani, Hiroyuki; Narabayashi, Isamu; Tanikake, Masato; Matsuki, Mitsuru; Uesugi, Yasuo

    2005-01-01

    We examined the effectiveness of multidetector-row CT (MD-CT) in the diagnosis and evaluation of cardiovascular anomalies in infants. MD-CT was performed 34 times on 21 patients with cardiovascular anomalies. We performed three evaluations: 1) The assessment of the specificity of MD-CT in detecting the morphological features of cardiovascular anomalies. 2) The diameters of aortae with coronary artery (CoA), and the diameters of pulmonary artery, measured by using MD-CT were compared with those by angiography. 3) The amount of exposure to radiation was measured. 1) MD-CT can detect CoA, pulmonary arteriovenous anomalies among extracardiac anomalies in all the patients. The diagnostic accuracy for intracardiac anomalies was poor as only six of the 15 anomalies could be accurately diagnosed. 2) The diameters of aortae and pulmonary artery obtained using MD-CT showed a good correlation with those obtained using arteriography (r=0.97, 0.95). 3) The average dose-length product was 269.2 mGy·cm. And the average effective dose was 5.1 mSv. MD-CT is not suitable for the evaluation of intracardiac anomalies, but is extremely effective in the evaluation of extracardiac major vascular anomalies. On the basis of the amount of information and noninvasive nature, MD-CT should be used first before angiography. (author)

  13. An assessment of communication skills of the MD/MS students of institute of medicine in Nepal

    Directory of Open Access Journals (Sweden)

    Jagdish Prasad Agrawal

    2013-09-01

    Full Text Available Introduction The main objective of this study was to assess the level of interpersonal communication skills of MD/MS resident doctors and to provide recommendations for the future. Methods Descriptive, cross sectional, qualitative and quantitative research design was used. 7- point Likert scale (0 to 6 MAAS-Global scoring instrument was used. The subjects of the research were the MD/MS residents from various departments of Maharajgunj Medical Campus (MMC of Institute of Medicine, Maharajgunj, Kathmandu. Out of 162 MD/MS residents, only 30 (18.5% MD/MS residents were selected for the sample size for the study from 1st, 2nd and 3rd year. One MD/MS resident was required four video recording to conduct four interviews with patients coming to the outpatient department. Results There was high degree of positive correlation between Information sharing and Management (r=0.746 whereas weak negative correlation on clarification and diagnosis (r=-0.011. Inter-rater correlation was established before hand and was satisfactory (p < 0.05. Conclusions This base line study of MD/MS residents shows that over all MD/MS residents are deficient in almost all the components of interpersonal communication skills. A communication skills training course in postgraduate medical education could improve the existing communication skills of the doctors in Nepal.

  14. Hybrid Pressure Retarded Osmosis−Membrane Distillation (PRO−MD) Process for Osmotic Power and Clean Water Generation

    KAUST Repository

    Han, Gang

    2015-05-20

    A novel pressure retarded osmosis−membrane distillation (PRO−MD) hybrid process has been experimentally conceived for sustainable production of renewable osmotic power and clean water from various waters. The proposed PRO−MD system may possess unique advantages of high water recovery rate, huge osmotic power generation, well controlled membrane fouling, and minimal environmental impacts. Experimental results show that the PRO−MD hybrid process is promising that not only can harvest osmotic energy from freshwater but also from wastewater. When employing a 2 M NaCl MD concentrate as the draw solution, ultrahigh power densities of 31.0 W/m2 and 9.3 W/m2 have been demonstrated by the PRO subsystem using deionized water and real wastewater brine as the feeds, respectively. Simultaneously, high purity potable water with a flux of 32.5−63.1 L/(m2.h) can be produced by the MD subsystem at 40−60 °C without any detrimental effects of fouling. The energy consumption in the MD subsystem might be further reduced by applying a heat exchanger in the hybrid system and using low-grade heat or solar energy to heat up the feed solution. The newly developed PRO−MD hybrid process would provide insightful guidelines for the exploration of alternative green technologies for renewable osmotic energy and clean water production.

  15. Overexpression of a repressor MdMYB15L negatively regulates anthocyanin and cold tolerance in red-fleshed callus.

    Science.gov (United States)

    Xu, Haifeng; Yang, Guanxian; Zhang, Jing; Wang, Yicheng; Zhang, Tianliang; Wang, Nan; Jiang, Shenghui; Zhang, Zongying; Chen, Xuesen

    2018-04-14

    The cold-induced metabolic pathway and anthocyanin biosynthesis play important roles in plant growth. In this study, we identified a bHLH binding motif in the MdMYB15L protein using protein sequence analyses. Yeast two-hybrid and pull-down assays showed that MdMYB15L could interact with MdbHLH33. Overexpressing MdMYB15L in red-fleshed callus inhibited the expression of MdCBF2 and resulted in reduced cold tolerance but did not affect anthocyanin levels. Chip-PCR and EMSA analysis showed that MdMYB15L could bind the type II cis-acting element found in the MdCBF2 promoter. Overexpressing MdMYB15L in red-fleshed callus overexpressing MdbHLH33 also reduced cold tolerance and reduced MdbHLH33-induced anthocyanin biosynthesis. Knocking out the bHLH binding sequence of MdMYB15L (LBSMdMYB15L) prevented LBSMdMYB15L from interacting with MdbHLH33. Overexpressing LBSMdMYB15L in red-fleshed callus overexpressing MdbHLH33 also reduced cold tolerance and reduced MdbHLH33-induced anthocyanin biosynthesis. Together, these results suggested that an apple repressor MdMYB15L might play a key role in the cold signaling and anthocyanin metabolic pathways. Copyright © 2018 Elsevier Inc. All rights reserved.

  16. Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth.

    Science.gov (United States)

    Dulay, Antonette T; Buhimschi, Catalin S; Zhao, Guomao; Oliver, Emily A; Abdel-Razeq, Sonya S; Shook, Lydia L; Bahtiyar, Mert O; Buhimschi, Irina A

    2015-06-01

    TLR4 mediates host responses to pathogens through a mechanism that involves protein myeloid differentiation-2 (MD-2) and its soluble form sMD-2. The role of sMD2 in intra-amniotic inflammation-induced preterm birth has not been previously explored. Human amniotic fluid (AF) sMD-2 was studied by Western blotting in 152 AF samples of patients who had an amniocentesis to rule-out infection (yes infection, n = 50; no infection, n = 50) or women with normal pregnancy outcome (second trimester genetic karyotyping, n = 26; third trimester lung maturity testing, n = 26). Histological localization and mRNA expression of MD2 in fetal membranes were studied by immunohistochemistry and RT-PCR. The ability of fetal membrane to release sMD-2 and inflammatory cytokines was studied in vitro. Human AF contains three sMD-2 proteoforms whose levels of expression were lower at term. Intra-amniotic infection upregulated sMD-2. MD-2 mRNA and immunohistochemistry findings concurred. In vitro, LPS and monensin increased, while cycloheximide decreased sMD-2 production. Recombinant sMD-2 modulated TNF-α and IL-6 levels in a dose- and time-dependent fashion. sMD2 proteoforms are constitutively present in human AF. The intensity of the intra-amniotic inflammatory response to bacteria or perhaps to other TLR4 ligands may be facilitated through synthesis and release of sMD2 by the amniochorion. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Neue Taxa von Lunatipula Edwards aus der mediterranen Subregion der Paläearktis (Diptera, Tipulidae, Tipula Linnaeus)

    NARCIS (Netherlands)

    Theischinger, Günther

    1977-01-01

    21 new species and one new subspecies of Lunatipula Edwards are described and their affinities are discussed. The new taxa are: Tipula (Lunatipula) hermes from Marocco, T.(L.) parallela from the Iberian peninsula, T.(L.) xyrophora from Italy and France, T.(L.) lubenauorum and rauschorum from Italy,

  18. Neue taxa von Lunatipula Edwards aus der mediterranen Subregion der Palaearktis (Diptera, Tipulidae, Tipula Linnaeus). IV. Fortsetzung

    NARCIS (Netherlands)

    Theischinger, Günther

    1982-01-01

    13 new species and two new subspecies of Lunatipula Edwards are described. The new taxa are: Tipula (Lunatipula) mallorca from Mallorca, T. (L.) bimacula minos from Crete, T. (L.) simova from Thasos, T. (L.) artemis asiaeminoris, T. (L.) christophi, T. (L.) franzressli, T. (L.) horsti, T. (L.)

  19. Thomas Secker M.D.: Archbishop and man-midwife.

    Science.gov (United States)

    Morgan-Guy, John

    2018-05-01

    This paper provides a biographical outline of the career of Thomas Secker, MD, who from 1758-68 was Archbishop of Canterbury. Although much has been written on Secker, this study seeks to highlight his training in medicine, which has been largely overlooked hitherto by historians.

  20. Investigating mental fitness and school connectedness in Prince Edward Island and New Brunswick, Canada.

    Science.gov (United States)

    Murnaghan, Donna; Morrison, William; Laurence, Courtney; Bell, Brandi

    2014-07-01

    As youth struggle with anxiety and depression, promoting positive mental fitness is a primary concern. Canadian school-based mental health programs that focus on positive psychology and positive mental health initiatives emphasize safe and supportive environments, student engagement, resilience, and self-determination. This study examined predictors of mental fitness and its 3 components (autonomy, competence, and relatedness). School Health Action Planning and Evaluation System-Prince Edward Island (SHAPES-PEI) and the New Brunswick Student Wellness Survey (NB SWS) are data collection and feedback systems that survey youth about 4 health behaviors. Grade 7-12 students in Prince Edward Island (N = 3318) and New Brunswick (N = 7314) completed a mental fitness questionnaire in 2008-2009 (PEI) and 2006-2007 (NB). Four linear regression models were conducted to examine student characteristics associated with mental fitness, autonomy, competence, and relatedness. Positive associations were found between school connectedness (p fitness, as well as autonomy, competence, and relatedness. There were also significant relationships between affect, pro-social and antisocial behaviors, tried smoking, and mental fitness. A better understanding of adolescent health and its predictors is needed. By identifying core parameters for mental fitness, we can inform how to address students' needs through appropriate programs and policies supporting healthy school environments. © 2014, American School Health Association.

  1. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

    Directory of Open Access Journals (Sweden)

    Adeline M Hajjar

    Full Text Available Although lipopolysaccharide (LPS stimulation through the Toll-like receptor (TLR-4/MD-2 receptor complex activates host defense against Gram-negative bacterial pathogens, how species-specific differences in LPS recognition impact host defense remains undefined. Herein, we establish how temperature dependent shifts in the lipid A of Yersinia pestis LPS that differentially impact recognition by mouse versus human TLR4/MD-2 dictate infection susceptibility. When grown at 37°C, Y. pestis LPS is hypo-acylated and less stimulatory to human compared with murine TLR4/MD-2. By contrast, when grown at reduced temperatures, Y. pestis LPS is more acylated, and stimulates cells equally via human and mouse TLR4/MD-2. To investigate how these temperature dependent shifts in LPS impact infection susceptibility, transgenic mice expressing human rather than mouse TLR4/MD-2 were generated. We found the increased susceptibility to Y. pestis for "humanized" TLR4/MD-2 mice directly paralleled blunted inflammatory cytokine production in response to stimulation with purified LPS. By contrast, for other Gram-negative pathogens with highly acylated lipid A including Salmonella enterica or Escherichia coli, infection susceptibility and the response after stimulation with LPS were indistinguishable between mice expressing human or mouse TLR4/MD-2. Thus, Y. pestis exploits temperature-dependent shifts in LPS acylation to selectively evade recognition by human TLR4/MD-2 uncovered with "humanized" TLR4/MD-2 transgenic mice.

  2. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica.

    Science.gov (United States)

    Hajjar, Adeline M; Ernst, Robert K; Fortuno, Edgardo S; Brasfield, Alicia S; Yam, Cathy S; Newlon, Lindsay A; Kollmann, Tobias R; Miller, Samuel I; Wilson, Christopher B

    2012-01-01

    Although lipopolysaccharide (LPS) stimulation through the Toll-like receptor (TLR)-4/MD-2 receptor complex activates host defense against Gram-negative bacterial pathogens, how species-specific differences in LPS recognition impact host defense remains undefined. Herein, we establish how temperature dependent shifts in the lipid A of Yersinia pestis LPS that differentially impact recognition by mouse versus human TLR4/MD-2 dictate infection susceptibility. When grown at 37°C, Y. pestis LPS is hypo-acylated and less stimulatory to human compared with murine TLR4/MD-2. By contrast, when grown at reduced temperatures, Y. pestis LPS is more acylated, and stimulates cells equally via human and mouse TLR4/MD-2. To investigate how these temperature dependent shifts in LPS impact infection susceptibility, transgenic mice expressing human rather than mouse TLR4/MD-2 were generated. We found the increased susceptibility to Y. pestis for "humanized" TLR4/MD-2 mice directly paralleled blunted inflammatory cytokine production in response to stimulation with purified LPS. By contrast, for other Gram-negative pathogens with highly acylated lipid A including Salmonella enterica or Escherichia coli, infection susceptibility and the response after stimulation with LPS were indistinguishable between mice expressing human or mouse TLR4/MD-2. Thus, Y. pestis exploits temperature-dependent shifts in LPS acylation to selectively evade recognition by human TLR4/MD-2 uncovered with "humanized" TLR4/MD-2 transgenic mice.

  3. Louise Edwards, Gender, Politics, and Democracy: Women’s Suffrage in China

    OpenAIRE

    Dirlik, Arif

    2009-01-01

    Gender, Politics, and Democracy retrace les luttes des femmes chinoises pour obtenir le droit de vote, depuis le tournant du XXe siècle jusqu’à la veille de la victoire des communistes en 1949. Edwards soutient que le terme « canzheng », suggérant la participation politique en général, était compris par les femmes activistes politiques de la première moitié du XXe siècle dans le sens plus concret de « participation au vote», « centré sur le double droit de voter et de se présenter aux électio...

  4. Final Environmental Assessment (EA), Long-Term Integrated Management of Mission-Generated Solid Waste, Edwards Air Force Base, California

    Science.gov (United States)

    2016-11-28

    surrounding communities within the Antelope Valley. Major industries in the area include agriculture, mining, and tourism , in addition to aerospace...festivals, sports , and other leisure pursuits, plus the attractions of the nearby Los Angeles metropolitan area make Edwards AFB a great jumping-off

  5. Dyadic Power Theory, Touch, and Counseling Psychology: A Response to Smith, Vogel, Madon, and Edwards (2011)

    Science.gov (United States)

    Dunbar, Norah E.; Abra, Gordon

    2012-01-01

    Smith, Vogel, Madon, and Edwards' (2011) recent article tested dyadic power theory (DPT) by examining the use of touch as a compliance-gaining tactic in the conflicts of married couples. In this response, we raise a methodological issue about the touch behaviors examined by Smith et al. and also pose a theoretical critique that their test of DPT…

  6. Sexual portraits: Edward Melcarth and homoeroticism in modern American art.

    Science.gov (United States)

    Griffey, Erin; Reay, Barry

    2012-01-01

    Although one will not find Edward Melcarth (1914-73) in the best recent histories of male homosexuality and American art, he was not always so spectral. Named in Life magazine in 1950 as one of the best young American artists, he exhibited as a painter, draftsman and sculptor and also practised as an illustrator, photographer and designer. His work survives in the Forbes Collection, in the Smithsonian Institution and in the art archives at the Kinsey Institute. We argue that Melcarth’s vision of the erotic was far broader than the traditional categories of sexuality that are perpetuated in art histories of homoeroticism in modern America – and that such a revisioning enables a reinterpretation of some of the better known images of homosexual art.

  7. 76 FR 15214 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

    Science.gov (United States)

    2011-03-21

    ...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... for Marine Events; Potomac River, Charles County, MD'' in the Federal Register (76 FR 1381). We... follows: Sec. 100.35-T05-1113 Special Local Regulations for Marine Events; Potomac River, Charles County...

  8. 76 FR 1381 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

    Science.gov (United States)

    2011-01-10

    ...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... Regulations for Marine Events; Potomac River, Charles County, MD. (a) Regulated area. The following location... local regulations during the ``Potomac River Sharkfest Swim'' amateur swim, a marine event to be held on...

  9. Learning the Way: Teaching and Learning with and for Youth from Refugee Backgrounds on Prince Edward Island

    Science.gov (United States)

    MacNevin, Joanne

    2012-01-01

    This article presents one component of a qualitative study that explored teaching and learning with and for youth from refugee backgrounds in Prince Edward Island (PEI) intermediate and high schools. Specifically, this article presents data and discussion regarding some of the challenges and professional development needs of teachers working with…

  10. Summary of LHC MD 369: DOROS vs WBTN in IR Stripline BPMs

    CERN Document Server

    Draskovic, Drasko; Calvo Giraldo, Eva; Olexa, Jakub; Gasior, Marek; CERN. Geneva. ATS Department

    2015-01-01

    The aim of this MD is to quantify the impact of the stripline beam position monitor (BPM) directivity with two acquisition chain electronics systems, WBTN (Wide Band Time Normalizer) and DOROS (Diode ORbit and Oscillation System). This impact depends on the relative position and intensity of the two beams at the location of the monitor. This note explains all the procedures of the LHC MD 369, which took place on 20/07/2015 and presents the obtained results.

  11. StandsSIM-MD: a Management Driven forest SIMulator

    Energy Technology Data Exchange (ETDEWEB)

    Barreiro, S.; Rua, J.; Tomé, M.

    2016-07-01

    Aim of the study. The existing stand level forest simulators available in Portugal were not developed with the aim of including up-to-date model versions and were limited in terms of accounting for forest management. The simulators’ platform, sIMfLOR was recently created to implement different growth models with a common philosophy. The objective was developing one easily-updatable, user-friendly, forest management and climate change sensitive simulator capable of projecting growth for the main tree species in Portugal. Area of the study: Portugal. Material and methods: The new simulator was programmed in a modular form consisting of several modules. The growth module integrates different forest growth and yield models (empirical and process-based) for the main wood production tree species in Portugal (eucalypt, umbrella and maritime pines); whereas the management module drives the growth projections along the planning horizon according to a range of forest management approaches and climate (at present only available for eucalypt). Main results: The main result is the StandsSIM-MD Management Driven simulator that overcomes the limitations of the existing stand level simulators. It is a step forward when compared to the models currently available in the sIMfLOR platform covering more tree species, stand structures and stand compositions. It is focused on end-users and it is based on similar concepts regarding the generation of required inputs and generated outputs. Research highlights: Forest Management Driven simulations approach. Multiple Prescriptions-Per-Stand functionality. StandsSIM-MD can be used to support landowners decisions on stand forest management. StandsSIM-MD simulations at regional level can be combined with optimization routines. (Author)

  12. Effect of salinity and temperature on treatment of concentrated wastewater from RO by FO-MD

    Science.gov (United States)

    Zhou, Yingru; Huang, Manhong; Deng, Qian

    2018-02-01

    In this study the appropriate temperature of the membrane distillation (MD) hot side (the permeation flux of MD was controlled by adjusting the hot side temperature) was selected according to the water flux of FO process so that the water transfer rate on both sides of FO and MD was consistent and the FO-MD process could be stable operation. When the salt concentration of feed solution was 30, 55, 80 and 100 g/L, the desalination rates changed little, which were 99.1%, 98.4%, 98.9% and 98.7%, respectively. The removal rate of COD was 93.8%, 94.2%, 91.6% and 92.7% which also changed little like the desalination rates. The removal rate of chromaticity increased with the increase of salinity, which attained 96.6%, 97.0%, 97.2% and 97.9%, respectively. This study proved that salinity of the feed solution affected little on the removal rate of contaminants but great on the water flux, with the increase of salinity from 30 to 100 g/L, the water flux was 6.05, 4.81, 4.33 and 3.87 LMH with the appropriate temperature (67.5±0.5, 64.5±0.5, 62.5±0.5 and 60.5±0.5 °C) of MD hot side. In a word, FO-MD was first used to treat the high salinity RO water with over 30 g/L total dissolved solids (TDS), FO-MD was a promising new process for high salinity wastewater treatment, and the hybrid system can solve the problem of lower draw solution concentration, and the high-quality production water will be obtained directly by this hybrid system with low membrane fouling tendency.

  13. A trap, neuter, and release program for feral cats on Prince Edward Island

    OpenAIRE

    Gibson, Karen L.; Keizer, Karen; Golding, Christine

    2002-01-01

    A new program to address the feral cat population on Prince Edward Island was undertaken during the spring and summer of 2001. Feral cats from specific geographic areas were trapped, sedated, and tested for feline leukemia virus and feline immunodeficiency virus. Healthy cats were neutered, dewormed, vaccinated, tattooed, and released to their area of origin. A total of 185 cats and kittens were trapped and tested during a 14-week period; 158 cats and kittens as young as 6 weeks of age were n...

  14. 77 FR 6708 - Special Local Regulations for Marine Events; Potomac River, Charles County, MD

    Science.gov (United States)

    2012-02-09

    ...-AA08 Special Local Regulations for Marine Events; Potomac River, Charles County, MD AGENCY: Coast Guard... River, Charles County, MD. (a) Regulated area. The following location is a regulated area: All waters of... local regulations during the ``Potomac River Sharkfest Swim'' amateur swim, a marine event to be held on...

  15. AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2018 POSITION STATEMENT ON INTEGRATION OF INSULIN PUMPS AND CONTINUOUS GLUCOSE MONITORING IN PATIENTS WITH DIABETES MELLITUS.

    Science.gov (United States)

    Grunberger, George; Handelsman, Yehuda; Bloomgarden, Zachary T; Fonseca, Vivian A; Garber, Alan J; Haas, Richard A; Roberts, Victor L; Umpierrez, Guillermo E

    2018-03-01

    This document represents the official position of the American Association of Clinical Endocrinologists and American College of Endocrinology. Where there are no randomized controlled trials or specific U.S. FDA labeling for issues in clinical practice, the participating clinical experts utilized their judgment and experience. Every effort was made to achieve consensus among the committee members. Position statements are meant to provide guidance, but they are not to be considered prescriptive for any individual patient and cannot replace the judgment of a clinician. AACE/ACE Task Force on Integration of Insulin Pumps and Continuous Glucose Monitoring in the Management of Patients With Diabetes Mellitus Chair George Grunberger, MD, FACP, FACE Task Force Members Yehuda Handelsman, MD, FACP, FNLA, MACE Zachary T. Bloomgarden, MD, MACE Vivian A. Fonseca, MD, FACE Alan J. Garber, MD, PhD, FACE Richard A. Haas, MD, FACE Victor L. Roberts, MD, MBA, FACP, FACE Guillermo E. Umpierrez, MD, CDE, FACP, FACE Abbreviations: AACE = American Association of Clinical Endocrinologists ACE = American College of Endocrinology A1C = glycated hemoglobin BGM = blood glucose monitoring CGM = continuous glucose monitoring CSII = continuous subcutaneous insulin infusion DM = diabetes mellitus FDA = Food & Drug Administration MDI = multiple daily injections T1DM = type 1 diabetes mellitus T2DM = type 2 diabetes mellitus SAP = sensor-augmented pump SMBG = self-monitoring of blood glucose STAR 3 = Sensor-Augmented Pump Therapy for A1C Reduction phase 3 trial.

  16. Opinion of stakeholders on existing curriculum for postgraduate (MD) course in Pharmacology: A survey.

    Science.gov (United States)

    Badyal, Dinesh K; Daniel, Sujit R

    2016-10-01

    To survey the opinion about various curricular components of Doctor of Medicine (MD) pharmacology curriculum in India by stakeholders, including faculty and students. An online survey was done to evaluate the various curricular components of MD pharmacology curriculum being used in India. A total of 393 respondents including faculty, MD students, and other stakeholders completed the survey. The survey was developed using SurveyMonkey platform and link to survey was E-mailed to stakeholders. The results were expressed as percentages. There was a balanced representation of respondents from various designations, teaching experience, regions, and age groups. Most of the respondents (83%) were aware of the MD pharmacology curriculum. However, they reported that it is more inclined to knowledge domain. About half of respondents (53%) said that animal experiments are being used. The most common teaching methods mentioned are seminars (98.5%), journal clubs (95%), and practical exercises by postgraduates (73%), but there is less use of newer methods (25%) in theory and less of clinical pharmacology exercise (39%) in practical classes. The log books are maintained but not assessed regularly. Internal assessment is sparingly used. The MD pharmacology curriculum needs to be made uniform at the national level and updated to include the newer methods in teaching-learning and assessment. There should be sharing of newer methods at a common platform implemented at the national level.

  17. Review of 40-year MD theses in Medical Oncology

    International Nuclear Information System (INIS)

    Zeeneldin, A.; Diyaa, A.; Elgammal, M.; Buhoush, W.; Manar Moneer, M.

    2014-01-01

    Background and objective: It is almost 40 years since the foundation of the Medical Oncology (MO) Department. We aimed to appraise the clinical research to fulfill the Medical Doctorate (MD) degree in MO at the National Cancer Institute, Cairo University (NCI, CU). Methods: This review included 62 MD theses containing 66 studies. They were reviewed regarding aims, type of study, clinical trial phase, design and methodology, statistical tests, results, limitations, consent and IRB approval. Theses were grouped into 3 periods: 1970-1989, 1990-1999 and 2000- 2008. Results: Almost 76% of the studies were interventional and 24% were observational. Informed consent and Institutional Review Board approval were mentioned in 18 and 2 studies, respectively. While all studies mentioned the aims, none, clearly mentioned the research question. Outcomes were mainly efficacy followed by safety. Study design was inadequately considered, especially in 70’s–80’s period (p = 0.038). Median sample size and study duration were almost stable through the three periods (p = 0.441, 0.354, respectively). Most of the studies used both descriptive and analytical statistical methods. In a descending order, researched cancers were lymphoma, breast, leukemia, liver, urinary bladder, lung and colorectal. The commonest stages researched were IV and III. The number of studies focused on assessing biomarkers, biomarkers plus drugs/procedures, drugs and procedures are 20, 20, 16 and 6, respectively. Conclusion: With time, research within MD theses in MO increased quantitatively and qualitatively. Improvements were noticeable in documentation of study design.

  18. 75 FR 76688 - Drawbridge Operation Regulation; Isle of Wight (Sinepuxent) Bay, Ocean City, MD

    Science.gov (United States)

    2010-12-09

    ..., mile 0.5, at Ocean City, with a vertical clearance of 13 feet above mean high tide in the closed...-AA09 Drawbridge Operation Regulation; Isle of Wight (Sinepuxent) Bay, Ocean City, MD AGENCY: Coast... Ocean City, MD. This proposed rule will require any mariner requesting an opening in the evening hours...

  19. Electric conductivity of solid solutions the Cs3-2xMxPO4 (M=Ba, Sr, Ca, Mg) systems

    International Nuclear Information System (INIS)

    Burmakin, E.I.; Stroev, S.S.; Shekhtman, G.Sh.; Antonov, B.D.

    2003-01-01

    The solid solutions in the Cs 3-2x M x PO 4 (M=Ba, Sr, Ca, Mg) system are synthesized and their thermal behavior and electric conductivity are studied. The introduction of the alkaline earth metal cations into cesium orthophosphates is accompanied by the shift of the phase transition occurring in the pure Cs 3 PO 4 at 450-620 Deg C into the low-temperature area as well as by increase in the cesium-cation conductivity at low temperatures. The electric conductivity in the area of existence of the Cs 3 PO 4 high-temperature modification slightly depends on the availability and concentration of the modifying additions, which make it possible to suppose the calcium sublattice structural disordering [ru

  20. 76 FR 44942 - Center for Scientific Review; Notice of Closed Meetings

    Science.gov (United States)

    2011-07-27

    ...: Sensation and Perception. Date: August 17-18, 2011. Time: 8 a.m. to 5 p.m. Agenda: To review and evaluate... (Virtual Meeting). Contact Person: John Bishop, PhD, Scientific Review Officer, Center for Scientific..., MD 20892 (Telephone Conference Call) Contact Person: Samuel C. Edwards, PhD, Chief, Center for...

  1. Illustration of the thermodynamical method of research into a critical state through the Rainford-Edwards model

    International Nuclear Information System (INIS)

    Soldatova, Je.D.; Snegyir'ov, M.G.

    2001-01-01

    The thermodynamical method for studing a critical state is illustrated by the example of critical behavior of metallic cerium in the frameworks of the improved Rainford-Edwards model. Thermodynamical stability of the model is investigated, and behavior of the whole complex of thermodynamical characteristics of the system is analyzed. It is concluded that the model has the first type of critical behaviour

  2. MD Test of a Ballistic Optics

    CERN Document Server

    Garcia-Tabares Valdivieso, Ana; Salvachua Ferrando, Belen Maria; Skowronski, Piotr Krzysztof; Solfaroli Camillocci, Matteo; Tomas Garcia, Rogelio; Wenninger, Jorg; Coello De Portugal - Martinez Vazquez, Jaime Maria; CERN. Geneva. ATS Department

    2016-01-01

    The ballistic optics is designed to improve the understanding of optical errors and BPM systematic effects in the critical triplet region. The particularity of that optics is that the triplet is switched off, effectively transforming the triplets on both sides of IR1 and IR5 into drift spaces. Advantage can be taken from that fact to localize better errors in the Q4-Q5-triplet region. During this MD this new optics was tested for the first time at injection with beam 2.

  3. Productions of Edward Albee's plays in Slovenia and the critics' response

    Directory of Open Access Journals (Sweden)

    Polonca Zalokar

    2009-12-01

    Full Text Available The article focuses on Edward Albee's four plays belonging to the theatre of the absurd which have been performed in Slovene theatres so far. The author analyses Albee's The 'Zoo Story, which has been produced four times, his American Dream and A Delicate Balance, which have been performed only once, and Albee's most known work in Slovenia, Who's Afraid of Virginia Woolf?, which has been produced six times in Slovene theatres. The continuation of this article focuses on  each of Albees above mentioned four plays including their production details, directors, actors, the comparison of critics' opinions and an estimation of how SIovene audiences accepted them according to the number of spectators and critics' responses.

  4. Gamma Ray Sterilization of Starr-Edwards Heart Valve Prostheses

    Energy Technology Data Exchange (ETDEWEB)

    Gibbons, J. R. P.; Alladine, M. F. [London Chest Hospital, London (United Kingdom)

    1967-09-15

    Starr-Edwards valves have normally been sterilized by exposure to ethylene oxide or by autoclaving. Patients having a prosthetic valve replacement are known to have a higher incidence of endocarditis in comparison with patients in which no prosthesis has been used. Ethylene oxide will only sterilize the surface of the valve and autoclaving has caused distortion of the polytetrafluorethylene ring. Work has been done on the effect of gamma radiation on the components of these valve prostheses and is given in detail. The bacteriological efficiency, at a total absorbed dose of 2. 5 Mrad, has been established. Thirty valves treated by this method have now been inserted and twelve patients have been examined post-operatively for a period of one to two years. All valves are working normally and there has been no evidence of blood-borne infection or malfunction of the valve. (author)

  5. Magnetic anomaly patterns over crustal blocks of the King Edward VII Peninsula, Marie Byrd Land, West Antarctica

    Directory of Open Access Journals (Sweden)

    M. Spano

    2000-06-01

    Full Text Available Within the framework of the GITARA II project an aeromagnetic survey was performed during the GANOVEXVII expedition (1992/1993 over the King Edward VII Peninsula in northwestern Marie Byrd Land (West Antarctica. This region which may represent the eastern flank of the Ross Sea rift system had previously been explored only at reconnaissance level. New total field and upward continued (10 km magnetic anomaly maps are produced and interpreted here to map and discuss the crustal structure of the Edward VII Peninsula. Tworound-shaped, high-amplitude magnetic anomalies are recognised over the Alexandra Mountains block. The anomalies are difficult to interpret since susceptibility data indicate the prevalence of non-magnetic rocks at the surface. A possible interpretation is that the anomalies are due to Cretaceous mafic intrusives distinct from weakly magnetic Byrd Coast Granite of the adjacent Rockefeller Mountains block. Alternatively the anomalies could be related to buried pluton-sized Devonian Ford Granodiorite intruded by dikes. If Cretaceous in age, the former intrusives revealed from the magnetics could also be responsible for contact metamorphism of the adjacent Alexandra Mountains migmatites. Lower amplitude circular anomalies over the Central Plateau and Prestrud Inlet are likely to be caused by unexposed Devonian Ford Granodiorite which crops out in the Ford Ranges. Elongated high-frequency anomalies of the Sulzberger Bay are similar to those recognised over seismically constrained Cenozoic rift-related volcanics of the Ross Sea. A broad magnetic low over the Sulzberger Ice Shelf may be indicative of a fault bounded graben-like basin with sedimentary infill. Overall recognition of magnetic anomaly patterns and trends reveals segmentation of the Edward VII Peninsula and of the adjacent marine areas in distinct crustal blocks. Faults may separate these blocks and they are interpreted to reflect multiple Cretaceous and maybe Cenozoic crustal

  6. Edward D. Churchill as a combat consultant: lessons for the senior visiting surgeons and today's military medical corps.

    Science.gov (United States)

    Cannon, Jeremy W; Fischer, Josef E

    2010-03-01

    In World War II, Edward D. Churchill volunteered as a combat consultant. In this role, he mentored many junior surgeons and challenged the Army leadership to treat hemorrhagic shock with blood rather than plasma. These lessons have continued relevance for today's Senior Visiting Surgeons and our military medical corps.

  7. Naphthalene induced activities on growth, respiratory metabolism and biochemical composition in juveniles of Metapenaeus affinis (H.Milne Edward, 1837)

    Digital Repository Service at National Institute of Oceanography (India)

    Ansari, Z.A.; Farshchi, P.; Faniband, M.

    Toxicity of naphthalene was carried out on Metapenaeus affinis (H. Milne Edward, 1837) to investigate its effects on growth, metabolic index and biochemical constituents. Growth rate in terms of weight gain was 32.13% in control, 12.12% in 0.125 ppm...

  8. MD210 Note: Creation of Hollow Bunches in the PSB

    CERN Document Server

    Oeftiger, Adrian; Findlay, Alan James; Hancock, Steven; Rumolo, Giovanni; CERN. Geneva. ATS Department

    2016-01-01

    MD210 aims for the creation of longitudinally hollow bunches in the CERN PS Booster. The first three sessions have been carried out using the radial loop feedback system in order to drive the beam on a dipolar parametric resonance (instead of the phase loop). It has been found that the damping by the phase loop inhibits the excitation of the resonance to a major extent. The hollow distributions generated under these circumstances fail to reach a satisfying bunching factor. Nonetheless, proving the principally successful application of this technique to the PS Booster promises good results once the phase loop system supports trim functions. The approach, actions and detailed results of the first three MD sessions are presented in this paper.

  9. Apresentações clínicas não usuais de pacientes portadores de síndrome de Patau e Edwards: um desafio diagnóstico? Unusual clinical presentations of patients with Patau and Edwards syndromes: a diagnostic challenge?

    Directory of Open Access Journals (Sweden)

    Paulo Ricardo G. Zen

    2008-09-01

    Full Text Available OBJETIVO: Relatar dois pacientes, um acometido por trissomia do cromossomo 13 em mosaico e outro por trissomia do cromossomo 18, ambos com apresentações clínicas não usuais. DESCRIÇÃO DO CASO: Paciente do sexo feminino de dois meses de idade, que apresentava deficiência de crescimento, dismorfias menores de face e de membros, paresia facial unilateral, cardiopatia congênita, hipotonia e evolução com o surgimento de manchas hipocrômicas e atraso do desenvolvimento neuropsicomotor. O segundo caso é de um paciente do sexo masculino, com 19 dias de vida, que também mostrava deficiência de crescimento, anomalias faciais menores, defeito radial, cardiopatia congênita e hipertonia. Os cariótipos por bandas GTG confirmaram o diagnóstico, respectivamente, de síndromes de Patau e de Edwards. COMENTÁRIOS: Os presentes relatos têm por objetivo alertar os pediatras sobre manifestações não usuais nas trissomias dos cromossomos 13 e 18, as quais podem dificultar a suspeita diagnóstica.OBJECTIVE: Report two patients, one with trisomy 13 mosaicism and the other with trisomy 18, both with unusual clinical presentations. CASE DESCRIPTION: The first case was a female patient with two months of age who presented growth deficiency, minor dysmorphia of face and limbs, unilateral facial paresis, congenital heart defect and hypotonia, who developed hypochromic spots and neuropsychomotor delay. The second case was a male patient with 19 days of age who also had growth deficiency, minor facial anomalies, radial defect, congenital heart defect and hypertonia. GTG-Banding karyotypes confirmed the diagnosis of Patau and Edwards syndromes respectively. COMMENTS: The aim of these reports is to call attention to the fact that Patau and Edwards syndromes may present an unusual pattern of abnormalities, making the diagnostic hypothesis difficult.

  10. A conceptual model of the hydrogeologic framework, geochemistry, and groundwater-flow system of the Edwards-Trinity and related aquifers in the Pecos County region, Texas

    Science.gov (United States)

    Bumgarner, Johnathan R.; Stanton, Gregory P.; Teeple, Andrew; Thomas, Jonathan V.; Houston, Natalie A.; Payne, Jason; Musgrove, MaryLynn

    2012-01-01

    A conceptual model of the hydrogeologic framework, geochemistry, and groundwater-flow system of the Edwards-Trinity and related aquifers, which include the Pecos Valley, Igneous, Dockum, Rustler, and Capitan Reef aquifers, was developed as the second phase of a groundwater availability study in the Pecos County region in west Texas. The first phase of the study was to collect and compile groundwater, surface-water, water-quality, geophysical, and geologic data in the area. The third phase of the study involves a numerical groundwater-flow model of the Edwards-Trinity aquifer in order to simulate groundwater conditions based on various groundwater-withdrawal scenarios. Resource managers plan to use the results of the study to establish management strategies for the groundwater system. The hydrogeologic framework is composed of the hydrostratigraphy, structural features, and hydraulic properties of the groundwater system. Well and geophysical logs were interpreted to define the top and base surfaces of the Edwards-Trinity aquifer units. Elevations of the top and base of the Edwards-Trinity aquifer generally decrease from the southwestern part of the study area to the northeast. The thicknesses of the Edwards-Trinity aquifer units were calculated using the interpolated top and base surfaces of the hydrostratigraphic units. Some of the thinnest sections of the aquifer were in the eastern part of the study area and some of the thickest sections were in the Pecos, Monument Draw, and Belding-Coyanosa trough areas. Normal-fault zones, which formed as growth and collapse features as sediments were deposited along the margins of more resistant rocks and as overlying sediments collapsed into the voids created by the dissolution of Permian-age evaporite deposits, were delineated based on the interpretation of hydrostratigraphic cross sections. The lowest aquifer transmissivity values were measured in the eastern part of the study area; the highest transmissivity values were

  11. JST Thesaurus Headwords and Synonyms: Md [MeCab user dictionary for science technology term[Archive

    Lifescience Database Archive (English)

    Full Text Available MeCab user dictionary for science technology term Md 名詞 一般 * * * * メンデレビウム メンデレビウム メンデレビューム Thesaurus2015 200906022783221535 C CA03 UNKNOWN_1 Md

  12. Review of 40-year MD theses in medical oncology.

    Science.gov (United States)

    Zeeneldin, Ahmed; Diyaa, Amira; Moneer, Manar; Elgammal, Mosaad; Buhoush, Wafa

    2014-09-01

    It is almost 40 years since the foundation of the Medical Oncology (MO) Department. We aimed to appraise the clinical research to fulfill the Medical Doctorate (MD) degree in MO at the National Cancer Institute, Cairo University (NCI, CU). This review included 62 MD theses containing 66 studies. They were reviewed regarding aims, type of study, clinical trial phase, design and methodology, statistical tests, results, limitations, consent and IRB approval. Theses were grouped into 3 periods: 1970-1989, 1990-1999 and 2000-2008. Almost 76% of the studies were interventional and 24% were observational. Informed consent and Institutional Review Board approval were mentioned in 18 and 2 studies, respectively. While all studies mentioned the aims, none, clearly mentioned the research question. Outcomes were mainly efficacy followed by safety. Study design was inadequately considered, especially in 70's-80's period (p=0.038). Median sample size and study duration were almost stable through the three periods (p=0.441, 0.354, respectively). Most of the studies used both descriptive and analytical statistical methods. In a descending order, researched cancers were lymphoma, breast, leukemia, liver, urinary bladder, lung and colorectal. The commonest stages researched were IV and III. The number of studies focused on assessing biomarkers, biomarkers plus drugs/procedures, drugs and procedures are 20, 20, 16 and 6, respectively. With time, research within MD theses in MO increased quantitatively and qualitatively. Improvements were noticeable in documentation of study design. Copyright © 2014. Production and hosting by Elsevier B.V.

  13. Síndrome de Edwards de larga supervivencia: Efecto del tratamiento rehabilitador integral

    Directory of Open Access Journals (Sweden)

    Katia Bustillos-Villalta

    2014-04-01

    Full Text Available Se reporta el caso de una adolescente de 15 años de edad con diagnóstico de Síndrome de Edwards referida a nuestro servicio de rehabilitación desde el primer año de vida. La paciente presenta rasgos dismórficos múltiples y desde el año de edad ha recibido tratamiento rehabilitador integral en: terapia física, terapia ocupacional, terapia de lenguaje, terapia de modificación de conducta y terapia de psicomotricidad. Actualmente asiste a terapia ocupacional y terapia de modificación de conducta, con controles médicos periódicos.

  14. El modelo de servicio de un MBA con enfoque humanístico

    Directory of Open Access Journals (Sweden)

    Ernesto Barrera Duque

    2011-06-01

    Full Text Available Este artículo de investigación tiene como objetivo establecer los elementos fundamentales de la experiencia del estudiante MBA en el programa de una institución educativa colombiana. Mediante la combinación del análisis narrativo y la teoría fundamentada, ambos dentro de la modalidad de metodología cualitativa, se hallaron categorías fundamentales en la experiencia de servicio. La interacción con los profesores, la interacción con los directores de estudio, el contexto organizacional de la institución educativa, la interacción con otros participantes y el diseño del programa centrado en el participante, fueron los inductores de la experiencia. Además, se encontró que el método del caso era un mediador importante para verter una experiencia de carácter práctico. Finalmente, los elementos de impacto en el estudiante fueron el desarrollo de habilidades directivas y la transformación personal integral. El enfoque humanístico, imbuido en todas las categorías, sirvió de pliegue entre ellas, indicando que este elemento es consistente y potencia la formación orientada a mejorar el desempeño laboral y personal de los participantes. Además, este enfoque, que es evidente en la experiencia, es valorado por los estudiantes.

  15. 75 FR 8193 - Jeri Hassman, M.D.; Denial of Application

    Science.gov (United States)

    2010-02-23

    ... is buying drugs on the street. Id. at 1006. With respect to requests for early refills, Dr. Hare... Part II Department of Justice Drug Enforcement Administration Jeri Hassman, M.D.; Denial of...; [[Page 8194

  16. W. Edwards Deming, quality analysis, and total behavior management.

    Science.gov (United States)

    Saunders, R R; Saunders, J L

    1994-01-01

    During the past 10 years, the inclusion of the word "quality" in descriptions of production methods, management approaches, educational systems, service system changes, and so forth, has grown exponentially. It appears that no new approach to any problem is likely to be given much consideration today without overt acknowledgment that some improvement in quality must be the outcome. The origins of the importance of quality are primarily rooted in the awakening recognition of the influence of W. Edwards Deming in the post-World War II restoration of Japanese industry. We provide a brief overview of Deming's approach to modernizing management methods and discuss recent criticisms from the field of organizational behavior management that his approach lacks emphasis on the role of reinforcement. We offer a different analysis of Deming's approach and relate its evolution to the contingencies of reinforcement for the behavior of consulting. We also provide an example of problem solving with Deming's approach in a social service setting familiar to many behavior analysts.

  17. MD-portal: Highly Effective Website for Nuclear Materials Information Management

    International Nuclear Information System (INIS)

    Kil, Soyeon; Lee, Gyeonggeun; Kwon, Junhyun

    2014-01-01

    A web-based system is widespread in not only everyday activities but also business fields. In past years, the systematic information of various properties of materials usually has been provided as tabulated documents; however it recently has been provided as web-based DB. There are many websites providing material properties information, representative examples include MatWeb from the United States, Granta MI from England and MatNavi from Japan. In 2003, the nuclear materials division in KAERI established a website about nuclear materials property DB, called MatDB. To inherit it, a website called MD-portal has been recently set up to release degradation information and various properties of nuclear materials. In this presentation, the structure and characteristics of MD-portal will be mentioned, and comments on its application will be given

  18. El sutil regodeo de la decadencia. Dinámicas urbanas, fronteras permeables y tiempo suspendido en El museo de cera de Jorge Edwards

    Directory of Open Access Journals (Sweden)

    Giuseppe Gatti

    2012-06-01

    Full Text Available El objetivo del presente artículo consiste en proponer una relectura de la novela El museo de cera, que el escritor chileno Jorge Edwards publicó en 1981, concentrando la atención no sólo en la habitual interpretación crítica que evidencia la lúcida condena satírica del pensamiento reaccionario chileno, sino abordando la trama desde una perspectiva que ilumina la relación entre tiempo individual y colectivo. En paralelo, se examina la representación de la decadencia de una arquitectura sociopolítica, poniendo en relación las imágenes ficcionales de Edwards con las representaciones del declive presentes en la narrativa austrohúngara de comienzos del siglo xx. Se analizan, finalmente, las dinámicas de ósmosis entre los dos espacios geosociales descritos en la ficción evidenciando la permeabilidad de sectores en apariencia opuestos.The purpose of the present article consists of proposing a different interprtetation of the novel El museo de cera, which the Chilean writer Jorge Edwards published in 1981: we will concentrate not only in the habitual critical interpretation that confirms the lucid satirical sentence of the reactionary Chilean thought, but we will approach the plot from a perspective that demonstrates the relation between individual and collective time. At the same time, we analyze the representation of the decadence of a social and political structure, by connecting the fictional images from Edwards with the representations of the decline presented in the Austro-Hungarian narrative of the beginning of the 20th century. Finally, we examine the dynamics of osmosis between the two geosocial contexts described in the fiction demonstrating the permeability of sectors by all appearances opposite.

  19. The Structural Basis for Lipid and Endotoxin Binding in RP105-MD-1, and Consequences for Regulation of Host Lipopolysaccharide Sensitivity.

    Science.gov (United States)

    Ortiz-Suarez, Maite L; Bond, Peter J

    2016-01-05

    MD-1 is a member of the MD-2-related lipid-recognition (ML) family, and associates with RP105, a cell-surface protein that resembles Toll-like receptor 4 (TLR4). The RP105⋅MD-1 complex has been proposed to play a role in fine-tuning the innate immune response to endotoxin such as bacterial lipopolysaccharide (LPS) via TLR4⋅MD-2, but controversy surrounds its mechanism. We have used atomically detailed simulations to reveal the structural basis for ligand binding and consequent functional dynamics of MD-1 and the RP105 complex. We rationalize reports of endogenous phospholipid binding, by showing that they prevent collapse of the malleable MD-1 fold, before refining crystallographic models and uncovering likely binding modes for LPS analogs. Subsequent binding affinity calculations reveal that endotoxin specificity arises from the entropic cost of expanding the MD-1 cavity to accommodate bulky lipid tails, and support the role of MD-1 as a "sink" that sequesters endotoxin from TLR4 and stabilizes RP105/TLR4 interactions. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Percutaneous closure of paravalvular leaks after transcatheter aortic valve implantation with Edwards SAPIEN prosthesis: a report of two cases.

    Science.gov (United States)

    Estévez-Loureiro, Rodrigo; Salgado-Fernández, Jorge; Vázquez-González, Nicolás

    2013-02-01

    Significant periprosthetic aortic regurgitation after transcatheter aortic valve implantation with Edwards SAPIEN prosthesis has become a major concern of this technique given its association with impaired survival. We report the successful closure of such defects using vascular occlusion devices with significant improvement in clinical status of patients.